# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- FAD_binding_4 PF01565.18 EON95592.1 - 8.2e-22 77.1 7.8 1.1e-21 76.7 4.2 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EON95592.1 - 3.8e-09 36.2 0.2 9.8e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like DUF3292 PF11696.3 EON95593.1 - 2.6e-52 177.6 0.3 4e-52 176.9 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) GRAM PF02893.15 EON95593.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Med13_C PF06333.7 EON95593.1 - 0.12 10.8 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal SNF2_N PF00176.18 EON95594.1 - 3.7e-51 173.6 0.0 6.2e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EON95594.1 - 6e-26 90.1 4.3 6e-26 90.1 3.0 2.4 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EON95594.1 - 1.1e-14 54.0 0.0 6.3e-14 51.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EON95594.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SEC-C PF02810.10 EON95594.1 - 0.01 15.3 9.0 0.022 14.2 6.2 1.5 1 0 0 1 1 1 0 SEC-C motif Glyco_transf_28 PF03033.15 EON95595.1 - 5.2e-10 39.2 0.0 1.1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain p450 PF00067.17 EON95597.1 - 2.9e-48 164.5 0.0 1.3e-47 162.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Stathmin PF00836.14 EON95597.1 - 0.049 13.2 0.5 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Stathmin family G-alpha PF00503.15 EON95598.1 - 4e-116 387.9 0.4 4.8e-116 387.6 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EON95598.1 - 1.1e-13 50.7 1.0 1.6e-08 33.9 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EON95598.1 - 0.00047 19.3 1.2 0.053 12.6 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EON95598.1 - 0.0085 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EON95598.1 - 0.026 13.9 0.0 0.065 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EON95598.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EON95598.1 - 0.11 11.9 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CN_hydrolase PF00795.17 EON95600.1 - 7.5e-32 110.1 0.0 1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LCM PF04072.9 EON95600.1 - 0.055 13.0 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase CMAS PF02353.15 EON95601.1 - 2.1e-18 66.3 0.0 2.7e-15 56.2 0.0 2.1 1 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EON95601.1 - 2.9e-16 59.6 0.0 4.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON95601.1 - 8.2e-16 58.2 0.0 1.7e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95601.1 - 1.2e-15 57.4 0.3 4.1e-14 52.4 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95601.1 - 7e-13 49.1 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON95601.1 - 1.1e-12 48.2 0.0 2.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON95601.1 - 1.6e-07 31.6 0.1 5.5e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON95601.1 - 9.2e-07 28.9 0.0 2.8e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON95601.1 - 2.1e-05 23.9 0.1 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EON95601.1 - 0.00023 20.6 0.2 0.0013 18.1 0.1 2.0 1 1 1 2 2 2 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EON95601.1 - 0.00098 18.2 0.1 0.0074 15.4 0.1 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EON95601.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EON95601.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DOT1 PF08123.8 EON95601.1 - 0.0075 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 EON95601.1 - 0.018 14.7 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EON95601.1 - 0.019 14.9 0.1 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_PK PF05891.7 EON95601.1 - 0.03 13.6 0.3 0.091 12.0 0.2 1.7 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EON95601.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_M1 PF01433.15 EON95602.1 - 4.1e-72 243.4 0.0 5.6e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EON95602.1 - 8.7e-42 142.1 0.0 1.4e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EON95602.1 - 4.3e-17 62.3 0.7 7.3e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EON95602.1 - 0.28 11.1 1.8 1.7 8.6 1.2 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Glyco_hydro_3 PF00933.16 EON95603.1 - 4.7e-85 285.1 0.0 6.5e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON95603.1 - 2.2e-41 141.8 0.0 1.3e-40 139.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON95603.1 - 2.2e-22 78.7 0.1 3.7e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Kinesin PF00225.18 EON95604.1 - 1.9e-108 362.1 1.1 7e-108 360.2 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EON95604.1 - 6.3e-08 32.3 0.8 1.9e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 Kinesin protein KIF1B PF12423.3 EON95604.1 - 1.3e-05 25.0 0.5 4.8e-05 23.2 0.4 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EON95604.1 - 7.4e-05 22.7 0.0 0.00097 19.2 0.0 2.9 3 0 0 3 3 3 1 FHA domain PH PF00169.24 EON95604.1 - 9e-05 22.6 0.0 0.00044 20.3 0.0 2.3 1 1 0 1 1 1 1 PH domain AAA_22 PF13401.1 EON95604.1 - 0.3 11.2 2.3 0.56 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Uds1 PF15456.1 EON95605.1 - 5.5e-34 116.8 8.2 1.3e-33 115.6 5.7 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Spermine_synth PF01564.12 EON95606.1 - 1.6e-97 325.2 0.1 2.3e-97 324.7 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EON95606.1 - 5.5e-05 22.8 0.0 7.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95606.1 - 8.3e-05 23.1 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON95606.1 - 0.0022 18.4 0.2 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EON95606.1 - 0.0051 15.8 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 EON95606.1 - 0.019 14.1 0.2 0.11 11.6 0.1 2.0 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_23 PF13489.1 EON95606.1 - 0.029 14.0 0.0 0.069 12.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EON95606.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EON95606.1 - 0.051 14.4 0.0 0.099 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ECH PF00378.15 EON95607.1 - 1e-47 162.3 0.2 8.7e-45 152.7 0.1 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family FAD_binding_4 PF01565.18 EON95608.1 - 6e-16 58.1 0.9 1.1e-15 57.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON95608.1 - 2.5e-09 36.8 0.9 6.2e-09 35.6 0.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF1989 PF09347.5 EON95609.1 - 1e-32 112.8 0.0 1.2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HET PF06985.6 EON95610.1 - 5e-30 104.4 0.3 7.9e-30 103.8 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.19 EON95611.1 - 4.2e-40 137.7 0.1 5.8e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.20 EON95612.1 - 1.4e-13 51.0 0.1 2.2e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95612.1 - 1.3e-05 24.9 0.2 2.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 KR domain LamB_YcsF PF03746.11 EON95613.1 - 2.4e-68 229.8 0.0 2.9e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family RGS PF00615.14 EON95614.1 - 2.4e-05 24.4 0.0 0.00069 19.7 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain ADH_zinc_N PF00107.21 EON95616.1 - 2.7e-08 33.4 0.0 4.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95616.1 - 2.2e-06 27.3 0.1 3.4e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.3 EON95617.1 - 1.2e-05 24.1 0.0 1.3e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 EON95618.1 - 6.5e-78 262.1 34.4 8.1e-78 261.8 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON95618.1 - 2.3e-25 89.0 36.3 2.9e-25 88.7 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease PBCV_basic_adap PF08789.5 EON95618.1 - 0.16 11.6 0.1 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain Pyr_redox_3 PF13738.1 EON95619.1 - 4.4e-17 62.8 0.0 8.5e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON95619.1 - 3.6e-10 38.6 0.0 2.5e-09 35.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EON95619.1 - 5e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON95619.1 - 4.6e-05 23.2 0.1 0.003 17.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EON95619.1 - 0.00052 19.0 0.0 0.042 12.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EON95619.1 - 0.019 14.8 0.0 9.4 6.0 0.0 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EON95619.1 - 0.025 14.1 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Thi4 PF01946.12 EON95619.1 - 0.03 13.3 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family IlvN PF07991.7 EON95619.1 - 0.032 13.6 0.4 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 EON95619.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EON95619.1 - 0.15 10.4 0.5 4.4 5.6 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Acetyltransf_8 PF13523.1 EON95620.1 - 1.5e-24 86.6 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SGL PF08450.7 EON95621.1 - 0.00033 20.1 0.1 0.092 12.1 0.1 2.5 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Sugar_tr PF00083.19 EON95622.1 - 4.5e-21 74.9 17.7 1.2e-10 40.5 5.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON95622.1 - 1.1e-07 30.8 17.8 2e-06 26.8 12.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EON95622.1 - 0.0022 16.4 4.5 0.0022 16.4 3.1 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein DUF4492 PF14899.1 EON95622.1 - 2.4 7.7 5.3 5.9 6.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Aldose_epim PF01263.15 EON95623.1 - 1.5e-34 119.4 0.1 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.19 EON95624.1 - 6.7e-76 255.6 23.4 7.7e-76 255.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95624.1 - 3.5e-19 68.7 30.1 3.5e-19 68.7 20.9 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON95624.1 - 1.6e-08 33.3 22.2 7.3e-05 21.3 4.3 4.2 1 1 3 4 4 4 3 MFS/sugar transport protein SRPRB PF09439.5 EON95624.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1741 PF08427.5 EON95625.1 - 3.6e-86 288.4 0.6 1.1e-85 286.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) Orai-1 PF07856.7 EON95626.1 - 0.017 14.6 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity RskA PF10099.4 EON95626.1 - 0.034 13.9 0.3 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cmc1 PF08583.5 EON95626.1 - 0.94 9.2 11.1 1.3 8.8 1.9 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EON95626.1 - 2.9 7.8 6.7 7.8 6.5 0.2 2.7 3 0 0 3 3 3 0 CHCH domain DUF1074 PF06382.6 EON95627.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Sulfate_transp PF00916.15 EON95628.1 - 3.6e-69 232.8 7.9 5e-69 232.4 5.5 1.2 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EON95628.1 - 1.3e-08 34.2 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EON95628.1 - 0.039 13.9 0.9 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 STAS domain MFS_1 PF07690.11 EON95629.1 - 3.5e-30 104.9 56.4 2.5e-22 79.0 13.1 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95629.1 - 8e-10 37.8 7.8 8e-10 37.8 5.4 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter DUF500 PF04366.7 EON95630.1 - 2.6e-44 149.6 0.0 4.7e-44 148.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) MFS_1 PF07690.11 EON95631.1 - 4.5e-12 45.3 35.3 4.5e-12 45.3 24.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON95631.1 - 7.5e-12 45.0 1.9 7.5e-12 45.0 1.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 EON95631.1 - 8.3 5.7 15.8 0.57 9.5 0.1 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) MgsA_C PF12002.3 EON95632.1 - 3.2e-58 196.1 0.0 5.7e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EON95632.1 - 6.6e-14 52.2 0.1 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EON95632.1 - 4.2e-10 39.0 0.0 1.1e-09 37.6 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EON95632.1 - 7.1e-06 25.5 0.1 0.00019 20.9 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EON95632.1 - 1.9e-05 23.9 0.2 0.029 13.5 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EON95632.1 - 2.3e-05 24.1 0.0 0.00018 21.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EON95632.1 - 4.8e-05 23.0 0.1 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EON95632.1 - 0.00031 20.6 0.0 0.00063 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON95632.1 - 0.0004 20.4 0.9 0.015 15.2 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EON95632.1 - 0.0005 20.2 1.3 0.003 17.6 0.3 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EON95632.1 - 0.0033 16.4 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 EON95632.1 - 0.0035 17.1 0.2 0.38 10.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 EON95632.1 - 0.0066 15.2 0.0 0.019 13.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 EON95632.1 - 0.013 15.1 0.0 0.044 13.3 0.0 1.9 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EON95632.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EON95632.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_2 PF07724.9 EON95632.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) SKI PF01202.17 EON95632.1 - 0.057 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.1 EON95632.1 - 0.095 13.5 0.1 0.36 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EON95632.1 - 0.096 12.9 0.1 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EON95632.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EON95632.1 - 0.12 11.9 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sgf11 PF08209.6 EON95632.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) AAA_10 PF12846.2 EON95632.1 - 0.17 11.2 1.8 13 5.1 0.2 2.8 2 1 1 3 3 3 0 AAA-like domain AAA_28 PF13521.1 EON95632.1 - 0.31 10.9 1.5 1.1 9.2 1.0 1.9 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 EON95634.1 - 1.2e-11 44.7 1.3 2.2e-11 43.9 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON95634.1 - 9e-06 25.6 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON95634.1 - 0.0097 15.5 0.1 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON95634.1 - 0.013 14.9 0.1 0.044 13.2 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON95634.1 - 0.23 11.4 1.9 0.54 10.2 0.4 2.1 2 1 0 2 2 2 0 NADH(P)-binding MFS_1 PF07690.11 EON95635.1 - 5.4e-37 127.3 33.5 8.3e-37 126.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EON95635.1 - 0.01 16.2 1.4 0.035 14.4 0.6 2.2 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_23 PF13489.1 EON95636.1 - 2.9e-06 27.1 0.0 3.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AIG1 PF04548.11 EON95637.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 AIG1 family Mito_fiss_reg PF05308.6 EON95637.1 - 3.2 7.0 7.8 1.7 7.9 3.7 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.11 EON95639.1 - 4.2e-25 88.2 43.3 4.2e-25 88.2 30.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON95639.1 - 6e-12 44.5 14.4 1.3e-11 43.4 10.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HpcH_HpaI PF03328.9 EON95640.1 - 2.4e-35 121.4 0.0 3.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF4267 PF14087.1 EON95641.1 - 2.3e-24 85.1 3.7 2.9e-24 84.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) KR PF08659.5 EON95642.1 - 9.4e-39 132.9 0.0 2.3e-38 131.6 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EON95642.1 - 1.6e-31 109.4 0.0 1.2e-30 106.6 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EON95642.1 - 4.9e-19 68.6 0.0 1.5e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON95642.1 - 1.5e-14 54.0 0.0 2.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95642.1 - 7e-12 45.1 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON95642.1 - 5.2e-11 42.8 0.0 1.3e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95642.1 - 2.6e-10 40.8 0.0 9.5e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EON95642.1 - 1e-07 32.0 0.1 4e-07 30.1 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EON95642.1 - 1.1e-06 27.9 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EON95642.1 - 1.6e-06 28.3 0.0 1.7e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EON95642.1 - 7.8e-06 25.3 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EON95642.1 - 0.00068 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EON95642.1 - 0.00078 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EON95642.1 - 0.00092 19.2 0.0 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EON95642.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EON95642.1 - 0.095 12.1 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 EON95642.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Glyco_hydro_114 PF03537.8 EON95643.1 - 3.3e-13 49.2 0.0 6.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 AA_permease PF00324.16 EON95644.1 - 1.9e-110 369.4 46.2 2.4e-110 369.1 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON95644.1 - 2.9e-29 101.8 53.0 3.7e-29 101.5 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sod_Fe_C PF02777.13 EON95645.1 - 7.7e-41 138.2 0.1 1.3e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EON95645.1 - 2e-31 108.0 0.2 3.5e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ABC_tran PF00005.22 EON95646.1 - 5.1e-07 30.0 0.0 9.3e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter Aldedh PF00171.17 EON95647.1 - 1.3e-94 317.1 0.8 1.5e-94 316.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EON95647.1 - 7.2e-05 22.1 0.0 0.013 14.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) KMP11 PF03037.11 EON95647.1 - 0.087 13.4 0.2 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Gelsolin PF00626.17 EON95649.1 - 2e-36 123.4 0.1 1.2e-12 47.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat ADH_zinc_N PF00107.21 EON95650.1 - 1.5e-19 69.8 0.0 2.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON95650.1 - 5.6e-13 49.9 0.0 1.3e-12 48.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95650.1 - 7.5e-10 38.5 0.0 4.4e-09 36.0 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EON95651.1 - 1.6e-15 57.2 0.0 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON95651.1 - 1.5e-09 37.1 0.0 3.9e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EON95651.1 - 1.2e-08 34.0 0.0 2e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EON95651.1 - 2e-06 27.2 0.0 4.2e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EON95651.1 - 2.2e-06 27.7 1.6 7.9e-06 25.9 1.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EON95651.1 - 0.00043 20.2 1.8 0.00075 19.4 0.2 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON95651.1 - 0.024 14.2 0.4 0.081 12.5 0.3 1.8 1 1 0 1 1 1 0 KR domain DUF1456 PF07308.8 EON95651.1 - 0.039 13.9 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) RinB PF06116.7 EON95651.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator RinB Amidohydro_2 PF04909.9 EON95652.1 - 7.5e-40 137.2 0.2 9.9e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase AcetylCoA_hydro PF02550.10 EON95653.1 - 2.4e-47 161.2 0.0 3.9e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EON95653.1 - 6.8e-38 129.7 0.0 1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cellulase PF00150.13 EON95654.1 - 2.4e-32 112.2 0.0 3.4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.2 EON95655.1 - 4.6e-14 52.8 0.6 5.8e-14 52.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON95655.1 - 1.9e-05 24.3 0.1 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON95655.1 - 0.00049 19.8 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_lectin PF07938.7 EON95656.1 - 3.8e-06 26.4 4.2 0.025 13.8 0.2 3.2 1 1 1 2 2 2 2 Fungal fucose-specific lectin Lipase_GDSL_2 PF13472.1 EON95657.1 - 0.0003 20.9 0.0 0.00035 20.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EON95657.1 - 0.038 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.16 EON95658.1 - 5.9e-45 153.5 0.3 1.6e-44 152.1 0.2 1.7 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EON95658.1 - 0.096 11.8 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Epimerase PF01370.16 EON95660.1 - 8.1e-06 25.4 0.0 1.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON95660.1 - 0.018 13.9 0.0 0.67 8.8 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein NmrA PF05368.8 EON95661.1 - 3.9e-30 104.8 0.0 4.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON95661.1 - 2.9e-22 79.5 0.0 4.2e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON95661.1 - 1.4e-05 24.6 0.0 7.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EON95661.1 - 1.5e-05 25.0 0.3 2.8e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EON95661.1 - 0.0067 15.1 0.0 0.02 13.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.19 EON95661.1 - 0.0094 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TrkA_N PF02254.13 EON95661.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PLDc_2 PF13091.1 EON95661.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain Glycos_transf_1 PF00534.15 EON95662.1 - 1.1e-25 90.0 0.0 2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EON95662.1 - 2.2e-10 40.8 0.0 1.2e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EON95662.1 - 0.00084 19.5 0.0 0.0031 17.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Cellulase PF00150.13 EON95663.1 - 1.6e-28 99.7 0.5 2.3e-28 99.1 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.13 EON95663.1 - 0.088 12.1 0.1 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Alpha-amylase PF00128.19 EON95664.1 - 1e-83 281.3 0.9 1.4e-83 280.9 0.7 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain adh_short PF00106.20 EON95665.1 - 2e-21 76.6 0.0 2.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95665.1 - 1.4e-06 28.0 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON95665.1 - 7.6e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EON95665.1 - 2.3e-05 24.5 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EON95665.1 - 0.00015 21.2 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EON95665.1 - 0.00068 20.0 0.3 0.0016 18.8 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EON95665.1 - 0.00093 19.2 0.1 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EON95665.1 - 0.002 17.0 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EON95665.1 - 0.014 15.0 0.8 0.051 13.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EON95665.1 - 0.025 13.5 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EON95665.1 - 0.046 13.4 0.1 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 EON95665.1 - 0.082 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Sugar_tr PF00083.19 EON95666.1 - 3.7e-89 299.3 19.0 4.3e-89 299.1 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95666.1 - 1e-29 103.4 22.5 1.2e-28 99.8 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON95666.1 - 1.3e-06 27.0 23.6 0.00011 20.8 4.8 2.8 2 2 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EON95666.1 - 0.00014 20.2 4.2 0.00014 20.2 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.1 EON95666.1 - 4.1 6.7 9.8 21 4.4 3.2 2.7 2 1 0 2 2 2 0 Neurensin Sugar_tr PF00083.19 EON95667.1 - 2.7e-12 45.9 18.6 3.1e-12 45.8 12.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95667.1 - 3.5e-06 25.9 9.4 4.4e-06 25.6 6.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HD_4 PF13328.1 EON95667.1 - 0.043 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 HD domain UPF0220 PF05255.6 EON95667.1 - 2 7.6 6.7 0.58 9.3 2.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) Pec_lyase_C PF00544.14 EON95669.1 - 3e-40 137.8 2.4 4.2e-40 137.3 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EON95669.1 - 0.071 12.8 6.9 0.48 10.1 4.4 2.2 1 1 0 1 1 1 0 Right handed beta helix region AA_permease PF00324.16 EON95671.1 - 2.2e-145 484.7 35.4 2.5e-145 484.5 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON95671.1 - 2.4e-38 131.7 40.1 3.4e-38 131.2 27.8 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EON95672.1 - 8.1e-17 61.6 0.8 1.3e-16 60.9 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95672.1 - 1.5e-06 27.9 0.3 2.5e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EON95672.1 - 0.019 15.3 0.0 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Leu_leader PF08054.6 EON95672.1 - 1.9 8.1 3.8 27 4.4 0.0 2.6 2 0 0 2 2 2 0 Leucine operon leader peptide SDF PF00375.13 EON95673.1 - 9.8e-74 248.4 17.5 1.2e-73 248.2 12.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family adh_short PF00106.20 EON95674.1 - 1.5e-17 64.0 3.0 5e-17 62.3 1.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON95674.1 - 2.8e-11 43.4 0.7 3.7e-11 43.0 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON95674.1 - 3.4e-05 23.3 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON95674.1 - 0.0036 16.2 0.7 0.058 12.3 0.5 2.0 1 1 0 1 1 1 1 Male sterility protein PIN PF01850.16 EON95674.1 - 0.016 15.5 0.2 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 PIN domain NAD_binding_10 PF13460.1 EON95674.1 - 0.058 13.3 2.3 0.31 11.0 1.6 2.0 1 1 0 1 1 1 0 NADH(P)-binding DSPc PF00782.15 EON95675.1 - 2.6e-14 52.9 0.0 2e-05 24.1 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain adh_short PF00106.20 EON95676.1 - 2.4e-15 56.8 0.1 2.6e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95676.1 - 3.1e-08 33.5 0.1 3.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON95676.1 - 1.3e-05 25.0 0.0 1.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON95676.1 - 3.6e-05 23.3 0.1 4.3e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON95676.1 - 0.0049 16.8 0.2 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Hydrolase PF00702.21 EON95676.1 - 0.0083 16.5 0.0 0.0094 16.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NmrA PF05368.8 EON95676.1 - 0.011 14.9 0.2 0.013 14.7 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family CoA_binding_2 PF13380.1 EON95676.1 - 0.092 12.9 0.2 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 CoA binding domain SH3_9 PF14604.1 EON95677.1 - 1.1e-06 28.1 0.0 1.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EON95677.1 - 1.8e-05 24.0 0.0 3.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EON95677.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain CRA PF06589.6 EON95677.1 - 1.9 7.8 3.6 3.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Sugar_tr PF00083.19 EON95678.1 - 9.6e-87 291.4 23.8 1.1e-86 291.2 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95678.1 - 1.1e-25 90.1 36.8 3.5e-22 78.6 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON95678.1 - 1.4e-09 36.7 1.0 1.4e-09 36.7 0.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EON95678.1 - 0.06 13.1 4.1 0.061 13.1 0.3 2.8 3 0 0 3 3 3 0 MFS_1 like family Gate PF07670.9 EON95678.1 - 0.35 10.8 7.7 0.087 12.7 1.9 2.5 2 1 0 2 2 2 0 Nucleoside recognition HET PF06985.6 EON95679.1 - 0.023 14.8 0.4 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Med18 PF09637.5 EON95680.1 - 7.1e-29 101.0 0.0 8.2e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Vfa1 PF08432.5 EON95681.1 - 6.2e-32 111.0 23.9 7.2e-32 110.8 16.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 EON95681.1 - 0.19 11.5 16.8 0.25 11.2 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 EON95681.1 - 0.22 10.8 8.6 0.23 10.8 6.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDHD PF02862.12 EON95681.1 - 0.25 11.0 9.8 0.36 10.5 6.8 1.3 1 0 0 1 1 1 0 DDHD domain SET PF00856.23 EON95681.1 - 0.33 11.2 3.1 0.36 11.1 2.1 1.1 1 0 0 1 1 1 0 SET domain Raftlin PF15250.1 EON95681.1 - 0.39 9.2 9.5 0.44 9.0 6.6 1.0 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 EON95681.1 - 0.76 9.6 15.5 0.85 9.5 10.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cwf_Cwc_15 PF04889.7 EON95681.1 - 0.92 9.1 28.7 1.1 8.8 19.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2201_N PF13203.1 EON95681.1 - 0.97 8.5 8.4 1.1 8.4 5.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_11 PF13086.1 EON95681.1 - 1 8.8 6.8 1.1 8.7 4.7 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 EON95681.1 - 1.1 7.2 24.1 1.3 6.9 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.7 EON95681.1 - 1.3 8.4 36.1 1.7 8.1 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ycf1 PF05758.7 EON95681.1 - 1.5 6.4 18.8 1.5 6.4 13.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EON95681.1 - 1.5 8.1 33.4 1.9 7.7 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF262 PF03235.9 EON95681.1 - 1.6 8.6 9.3 1.7 8.5 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 Nop14 PF04147.7 EON95681.1 - 1.6 6.5 29.1 2 6.2 20.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3987 PF13148.1 EON95681.1 - 2.2 6.7 18.6 3.2 6.2 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) POX PF07526.6 EON95681.1 - 2.2 8.5 13.5 3.3 7.9 9.4 1.3 1 0 0 1 1 1 0 Associated with HOX Zip PF02535.17 EON95681.1 - 2.2 7.1 6.2 2.4 7.0 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 EON95681.1 - 2.2 7.7 24.6 3.1 7.2 17.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 EON95681.1 - 2.3 6.9 17.4 2.8 6.7 12.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Paf1 PF03985.8 EON95681.1 - 3.2 6.4 27.2 4 6.0 18.9 1.0 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.8 EON95681.1 - 3.3 6.1 17.3 3.9 5.8 12.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.7 EON95681.1 - 3.4 6.7 23.7 4.6 6.3 16.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BTV_NS2 PF04514.7 EON95681.1 - 3.6 6.3 20.5 4.4 6.0 14.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GCD14 PF08704.5 EON95681.1 - 3.7 6.9 9.4 4.7 6.6 6.5 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SAPS PF04499.10 EON95681.1 - 6.7 5.2 17.0 7.9 4.9 11.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Atg14 PF10186.4 EON95681.1 - 8.2 5.2 12.9 9.3 5.0 9.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2457 PF10446.4 EON95681.1 - 8.3 5.0 33.4 10 4.7 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-N PF05238.8 EON95681.1 - 8.4 5.3 14.3 9.4 5.1 9.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like NmrA PF05368.8 EON95682.1 - 9.9e-24 83.8 0.0 2.6e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON95682.1 - 2.6e-13 50.3 0.3 6.1e-13 49.1 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON95682.1 - 0.0051 16.2 0.0 0.0091 15.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EON95682.1 - 0.018 14.7 0.1 0.1 12.2 0.0 2.2 3 0 0 3 3 3 0 KR domain Semialdhyde_dh PF01118.19 EON95682.1 - 0.066 13.5 0.1 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LigB PF02900.13 EON95683.1 - 9.3e-41 139.6 0.1 1.1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PNK3P PF08645.6 EON95684.1 - 3.1e-55 185.9 0.0 6e-55 185.0 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EON95684.1 - 5e-31 107.5 0.0 9e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EON95684.1 - 0.00073 18.8 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EON95684.1 - 0.00081 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EON95684.1 - 0.0093 16.1 0.0 0.025 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain HAD_2 PF13419.1 EON95684.1 - 0.041 14.0 0.1 11 6.1 0.0 2.8 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EON95684.1 - 0.083 13.7 0.0 0.2 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 EON95685.1 - 6.8e-05 22.7 0.7 0.21 11.4 0.0 3.0 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EON95685.1 - 1.1 9.1 7.2 33 4.4 0.1 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Sugar_tr PF00083.19 EON95686.1 - 2.8e-25 88.8 16.3 3.1e-25 88.6 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95686.1 - 4.2e-09 35.5 11.6 4.8e-09 35.3 8.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3796 PF12676.2 EON95686.1 - 0.031 14.4 7.2 0.052 13.7 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2638 PF10937.3 EON95687.1 - 4e-37 127.6 3.3 6.5e-37 126.9 2.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Pectate_lyase_3 PF12708.2 EON95688.1 - 2.5e-52 178.2 17.8 1.8e-28 100.2 3.7 4.1 3 1 1 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 EON95688.1 - 5.7e-06 25.7 1.7 0.11 11.9 0.3 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.8 EON95688.1 - 0.0002 20.9 0.2 0.00061 19.4 0.2 1.8 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Peptidase_C14 PF00656.17 EON95689.1 - 3.2e-69 233.3 0.0 4.5e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain BCMA-Tall_bind PF09257.5 EON95689.1 - 0.038 13.9 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 BCMA, TALL-1 binding Cupin_1 PF00190.17 EON95690.1 - 4e-31 107.3 0.0 2.4e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EON95690.1 - 2.4e-26 91.0 1.6 2.3e-13 49.4 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EON95690.1 - 1.6e-09 36.9 0.0 0.00037 19.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EON95690.1 - 1.8e-07 30.9 0.2 0.00076 19.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EON95690.1 - 0.00035 20.1 0.0 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase FdtA PF05523.6 EON95690.1 - 0.0013 18.2 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 1 WxcM-like, C-terminal GPI PF06560.6 EON95690.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.9 EON95690.1 - 0.026 14.4 0.9 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 EON95690.1 - 0.032 13.6 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase 2OG-FeII_Oxy_5 PF13759.1 EON95690.1 - 0.074 13.3 0.1 7.6 6.8 0.0 3.1 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 EON95691.1 - 2e-22 79.4 32.7 7e-17 61.1 8.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95691.1 - 2.4e-10 39.6 15.0 4.3e-10 38.7 10.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MRI PF15325.1 EON95692.1 - 0.35 11.8 6.1 0.55 11.2 4.3 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection NAM-associated PF14303.1 EON95692.1 - 0.78 10.0 6.9 1 9.6 4.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Aldo_ket_red PF00248.16 EON95693.1 - 0.0018 17.1 0.0 0.0019 17.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EON95694.1 - 3.6e-28 98.2 18.3 4.5e-28 97.9 12.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95694.1 - 4e-08 32.2 19.3 1.3e-07 30.5 10.0 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EON95694.1 - 3.9e-07 28.6 5.1 3.9e-07 28.6 3.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GP41 PF00517.12 EON95694.1 - 0.014 15.0 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 Retroviral envelope protein Alpha_E2_glycop PF00943.14 EON95694.1 - 0.044 12.4 0.6 0.066 11.8 0.4 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein ArabFuran-catal PF09206.6 EON95695.1 - 1.6e-141 470.9 21.2 1.9e-141 470.7 14.7 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EON95695.1 - 3.7e-13 49.3 0.1 7.8e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) APH PF01636.18 EON95696.1 - 3.7e-14 53.0 0.0 5.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EON95696.1 - 0.038 13.1 0.0 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 EON95696.1 - 0.093 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EON95696.1 - 0.1 11.6 0.0 1 8.3 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Methyltransf_11 PF08241.7 EON95697.1 - 1.6e-21 76.5 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95697.1 - 2.6e-21 75.8 0.0 3.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON95697.1 - 1.4e-17 63.8 0.0 2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95697.1 - 1.2e-14 54.8 0.0 2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON95697.1 - 2.9e-14 53.3 0.0 4.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON95697.1 - 4.4e-12 46.2 0.0 7.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON95697.1 - 7.6e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON95697.1 - 4.2e-10 39.1 0.0 5.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EON95697.1 - 8.4e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EON95697.1 - 3.2e-06 26.3 0.0 7.9e-06 25.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EON95697.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 EON95697.1 - 0.00019 20.7 0.0 0.16 11.2 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.6 EON95697.1 - 0.0002 20.2 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EON95697.1 - 0.00083 18.5 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EON95697.1 - 0.0012 18.3 0.0 0.0039 16.5 0.0 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EON95697.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EON95697.1 - 0.0065 15.6 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EON95697.1 - 0.0097 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EON95697.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FmrO PF07091.6 EON95697.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) NodS PF05401.6 EON95697.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Nodulation protein S (NodS) PBP PF01161.15 EON95698.1 - 4.7e-20 71.9 0.0 5.6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran PF00005.22 EON95700.1 - 1.3e-30 106.4 0.1 1.9e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EON95700.1 - 3.5e-08 33.7 0.0 5.2e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EON95700.1 - 8.8e-06 25.0 1.6 0.005 16.1 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EON95700.1 - 0.003 17.4 1.0 0.0066 16.2 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_29 PF13555.1 EON95700.1 - 0.014 14.9 0.3 0.035 13.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EON95700.1 - 0.018 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EON95700.1 - 0.022 15.2 0.1 0.041 14.3 0.1 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 EON95700.1 - 0.097 12.5 0.9 0.77 9.6 0.6 2.1 1 1 0 1 1 1 0 AAA domain GHMP_kinases_N PF00288.21 EON95701.1 - 4.8e-12 45.7 2.7 8.3e-10 38.6 0.6 2.7 2 0 0 2 2 2 2 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EON95701.1 - 0.0035 17.5 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal DUF3248 PF11609.3 EON95701.1 - 0.0095 15.6 0.1 0.08 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3248) Fe-S_biosyn PF01521.15 EON95702.1 - 2.7e-16 59.4 0.0 3.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Calpain_inhib PF00748.14 EON95702.1 - 0.057 13.7 7.1 0.11 12.8 4.9 1.5 1 1 0 1 1 1 0 Calpain inhibitor Glyco_transf_54 PF04666.8 EON95703.1 - 5.9e-18 64.6 0.3 1.1e-09 37.5 0.0 3.0 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_tranf_2_3 PF13641.1 EON95703.1 - 0.079 12.7 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 FA_desaturase PF00487.19 EON95703.1 - 9.2 5.6 7.7 2.5 7.4 1.5 2.1 2 0 0 2 2 2 0 Fatty acid desaturase Abhydrolase_3 PF07859.8 EON95704.1 - 1.3e-30 106.5 0.1 1.9e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EON95704.1 - 0.00043 20.5 0.4 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain COesterase PF00135.23 EON95704.1 - 0.0021 16.8 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EON95704.1 - 0.0075 16.0 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3966 PF13110.1 EON95704.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Abhydrolase_6 PF12697.2 EON95704.1 - 0.17 11.7 3.9 0.34 10.7 2.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3445 PF11927.3 EON95706.1 - 2.6e-62 210.4 0.0 3e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Translin PF01997.11 EON95706.1 - 0.17 11.4 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Translin family Alk_phosphatase PF00245.15 EON95707.1 - 7.3e-85 285.1 0.0 8.8e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF647 PF04884.9 EON95711.1 - 4.6e-98 327.3 0.8 6.2e-98 326.9 0.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RepA_N PF06970.6 EON95711.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Rtt106 PF08512.7 EON95712.1 - 1e-24 86.2 0.0 2.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like bPH_2 PF03703.9 EON95712.1 - 0.0025 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial PH domain HhH-GPD PF00730.20 EON95713.1 - 1e-20 73.9 0.0 6.9e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EON95713.1 - 6.2e-11 41.7 0.0 1.7e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.19 EON95713.1 - 1.4e-07 30.8 0.0 2.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase HHH PF00633.18 EON95713.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif FMO-like PF00743.14 EON95714.1 - 3e-59 200.6 0.0 1.4e-51 175.3 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EON95714.1 - 5.7e-23 82.0 0.2 6e-17 62.3 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON95714.1 - 1.7e-09 37.8 0.0 5.8e-09 36.1 0.0 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON95714.1 - 3.5e-09 36.0 0.1 1.8e-07 30.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EON95714.1 - 1.8e-06 27.9 0.0 4.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON95714.1 - 4.1e-06 26.6 2.3 0.043 13.5 0.0 3.9 3 2 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EON95714.1 - 0.00012 22.3 1.8 0.05 14.0 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EON95714.1 - 0.0024 17.9 0.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EON95714.1 - 0.0087 15.1 0.6 0.028 13.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EON95714.1 - 0.013 15.7 0.0 2.4 8.4 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding IlvN PF07991.7 EON95714.1 - 0.026 13.8 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DAO PF01266.19 EON95714.1 - 0.027 13.4 0.2 0.54 9.1 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EON95714.1 - 0.042 12.9 0.0 0.042 12.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EON95714.1 - 0.046 12.8 0.1 7 5.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 EON95714.1 - 0.099 12.9 0.0 4.6 7.5 0.0 2.8 3 0 0 3 3 3 0 XdhC Rossmann domain ThiF PF00899.16 EON95714.1 - 0.53 10.1 2.6 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 ThiF family Spherulin4 PF12138.3 EON95716.1 - 2.9e-64 216.9 0.0 3.3e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Pyr_redox_2 PF07992.9 EON95717.1 - 2e-12 47.3 0.1 3.4e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON95717.1 - 5e-10 39.6 0.3 7.3e-07 29.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON95717.1 - 3e-06 27.4 0.1 0.00024 21.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON95717.1 - 0.0014 18.4 0.6 20 4.9 0.0 3.6 3 1 1 4 4 4 3 FAD-NAD(P)-binding DUF374 PF04028.8 EON95717.1 - 0.024 13.8 0.1 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) DAO PF01266.19 EON95717.1 - 0.15 10.9 0.6 8.9 5.0 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase WD40 PF00400.27 EON95719.1 - 6.7e-79 257.2 11.3 3.3e-12 45.7 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EON95719.1 - 1.2e-09 36.8 2.3 0.0003 19.0 0.1 4.0 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EON95719.1 - 1.8e-05 23.6 0.0 1.1 7.9 0.0 3.5 1 1 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EON95719.1 - 0.15 10.3 0.0 3.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain FAD_binding_6 PF00970.19 EON95720.1 - 6e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EON95720.1 - 4e-09 36.7 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EON95720.1 - 1.3e-07 32.1 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 EON95720.1 - 4.1e-05 23.2 0.1 9.1e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EON95720.1 - 0.00097 19.0 0.1 0.43 10.4 0.0 3.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain p450 PF00067.17 EON95721.1 - 2.1e-81 273.8 0.0 2.5e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EON95722.1 - 2.9e-32 111.8 5.5 1.4e-27 96.4 0.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON95722.1 - 0.00075 18.3 7.5 0.011 14.4 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EON95724.1 - 2e-20 72.6 0.4 4.2e-20 71.6 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON95724.1 - 0.0092 15.8 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like AftA_N PF12250.3 EON95724.1 - 0.05 12.3 0.1 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal PhyH PF05721.8 EON95725.1 - 2.4e-17 63.6 0.0 3.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 EON95725.1 - 0.00053 19.7 0.2 0.04 13.5 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family KdpD PF02702.12 EON95725.1 - 0.049 12.7 0.1 0.08 12.0 0.1 1.2 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Sugar_tr PF00083.19 EON95726.1 - 4.4e-103 345.2 16.5 5.3e-103 345.0 11.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95726.1 - 1.1e-25 90.1 43.6 4.8e-23 81.4 15.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EON95726.1 - 0.003 16.3 0.2 0.003 16.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) OPT PF03169.10 EON95727.1 - 4.5e-178 593.5 49.5 5.1e-178 593.3 34.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1049 PF06305.6 EON95727.1 - 0.52 9.8 8.7 0.69 9.4 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) RasGEF PF00617.14 EON95728.1 - 5e-54 182.8 0.0 7.4e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EON95728.1 - 0.027 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif PLU-1 PF08429.6 EON95728.1 - 0.056 12.3 0.5 0.099 11.5 0.3 1.3 1 0 0 1 1 1 0 PLU-1-like protein adh_short PF00106.20 EON95729.1 - 2e-19 70.1 0.0 2.5e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON95729.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON95729.1 - 8.7e-08 32.0 0.1 2.8e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON95729.1 - 0.00022 21.2 0.1 0.00041 20.4 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EON95729.1 - 0.0031 16.9 0.1 0.0089 15.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EON95729.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EON95729.1 - 0.021 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EON95729.1 - 0.032 13.2 0.1 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 EON95729.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EON95729.1 - 0.074 13.4 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AA_permease PF00324.16 EON95730.1 - 4.8e-76 256.0 27.0 5.7e-76 255.7 18.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON95730.1 - 1.3e-24 86.5 25.4 1.6e-24 86.2 17.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4077 PF13295.1 EON95730.1 - 0.0012 18.5 4.1 0.0025 17.5 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4077) Bacteriocin_IIc PF10439.4 EON95730.1 - 0.28 11.3 6.5 1.1 9.3 4.5 2.0 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide CLASP_N PF12348.3 EON95732.1 - 1.8e-07 30.7 0.0 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 EON95732.1 - 2.9e-07 30.0 2.1 0.47 10.6 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat APG6 PF04111.7 EON95732.1 - 0.0054 15.8 2.7 0.0054 15.8 1.9 1.7 2 0 0 2 2 2 1 Autophagy protein Apg6 Adaptin_N PF01602.15 EON95732.1 - 0.0058 15.0 0.3 2.9 6.0 0.0 2.7 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 EON95732.1 - 0.045 13.6 1.7 0.31 10.8 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EON95732.1 - 0.088 12.7 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation TAN PF11640.3 EON95732.1 - 0.094 12.4 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair HALZ PF02183.13 EON95732.1 - 0.61 9.8 7.8 1.8 8.3 2.3 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EON95732.1 - 0.66 9.7 15.2 0.037 13.7 2.7 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EON95732.1 - 0.94 9.4 12.0 0.48 10.4 0.8 3.8 4 0 0 4 4 4 0 bZIP transcription factor IncA PF04156.9 EON95732.1 - 1.4 8.4 7.7 0.05 13.1 0.8 1.9 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EON95732.1 - 1.8 8.9 3.7 29 5.0 2.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Dioxygenase_C PF00775.16 EON95734.1 - 3.9e-24 84.9 0.0 5.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EON95734.1 - 4.2e-12 45.8 0.1 6.4e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EON95734.1 - 0.00027 20.9 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1992 PF09350.5 EON95735.1 - 2.7e-25 87.9 0.1 7.9e-25 86.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) SAPS PF04499.10 EON95736.1 - 2e-191 636.7 0.3 9.1e-191 634.6 0.0 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Sld5 PF05916.6 EON95737.1 - 2.7e-13 50.1 0.0 3.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FAD_binding_4 PF01565.18 EON95738.1 - 5.5e-22 77.7 0.1 1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON95738.1 - 0.029 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Aldo_ket_red PF00248.16 EON95739.1 - 1.7e-50 171.4 0.0 1.9e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1286 PF06939.6 EON95740.1 - 0.0016 18.5 0.2 0.022 14.9 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1286) DUF4064 PF13273.1 EON95740.1 - 0.0029 17.6 3.1 0.5 10.5 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) HET PF06985.6 EON95741.1 - 8.7e-24 84.2 0.7 1.2e-23 83.8 0.5 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 EON95742.1 - 5.5e-26 91.8 0.0 7e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON95742.1 - 2.5e-25 89.3 0.9 3.3e-25 88.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95742.1 - 5.9e-08 32.5 0.2 8e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EON95742.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EON95742.1 - 0.045 13.3 0.5 0.075 12.6 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EON95742.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.16 EON95744.1 - 1.3e-29 102.9 0.0 1.4e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCFC PF07842.7 EON95745.1 - 1.5e-79 267.2 9.0 1.5e-79 267.2 6.2 1.8 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EON95745.1 - 1.9e-15 56.3 2.2 5.2e-15 54.9 1.5 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 EON95745.1 - 2.9e-15 56.2 15.5 2.9e-15 56.2 10.8 2.6 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 EON95745.1 - 1.8e-07 30.9 0.6 1.8e-07 30.9 0.4 2.6 2 1 1 3 3 3 1 DExH-box splicing factor binding site FUSC PF04632.7 EON95745.1 - 0.95 7.8 2.6 1.3 7.3 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATP-synt_E PF05680.7 EON95745.1 - 8.1 6.4 8.6 0.24 11.4 0.8 2.3 2 0 0 2 2 2 0 ATP synthase E chain Fungal_trans_2 PF11951.3 EON95746.1 - 1.2e-14 53.6 0.0 2.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON95746.1 - 7.1e-08 32.2 8.7 7.1e-08 32.2 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 EON95747.1 - 1.6e-20 73.6 0.0 2.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Candida_ALS_N PF11766.3 EON95747.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Dpy19 PF10034.4 EON95748.1 - 0.73 7.9 3.0 0.9 7.6 2.1 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Glycoprotein_B PF00606.13 EON95748.1 - 0.74 7.7 3.8 0.83 7.5 2.6 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Fungal_trans PF04082.13 EON95749.1 - 8.4e-05 21.5 0.0 0.00017 20.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 EON95750.1 - 2e-82 276.6 0.0 2.3e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase WW PF00397.21 EON95751.1 - 7.1e-05 22.5 3.5 0.00015 21.5 2.4 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EON95751.1 - 0.0043 17.1 10.1 0.0058 16.7 7.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TPR_2 PF07719.12 EON95751.1 - 1.7 8.7 6.4 3.5 7.7 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4404 PF14357.1 EON95751.1 - 4.1 7.8 5.2 7.5 7.0 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF2481 PF10654.4 EON95752.1 - 0.038 13.6 0.1 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) LisH PF08513.6 EON95752.1 - 0.059 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 LisH Herpes_UL82_83 PF05784.6 EON95753.1 - 0.025 13.3 0.0 0.047 12.4 0.0 1.3 2 0 0 2 2 2 0 Betaherpesvirus UL82/83 protein N terminus AntA PF08346.7 EON95753.1 - 0.093 12.9 0.7 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 AntA/AntB antirepressor FAD_binding_3 PF01494.14 EON95754.1 - 7e-21 74.6 0.4 3.8e-09 36.0 0.3 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON95754.1 - 8.3e-09 34.8 0.5 8.8e-06 24.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON95754.1 - 1e-07 31.8 0.2 2.2e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EON95754.1 - 2.9e-07 29.7 0.7 5e-07 28.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EON95754.1 - 1.1e-06 28.9 0.1 8.2e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON95754.1 - 1.2e-06 27.2 0.1 1.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EON95754.1 - 1.7e-06 27.3 0.2 2.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON95754.1 - 1.3e-05 25.2 0.2 3e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON95754.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EON95754.1 - 0.00019 20.1 0.9 0.00037 19.2 0.2 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 EON95754.1 - 0.00035 19.7 0.3 0.028 13.5 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EON95754.1 - 0.00066 19.2 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EON95754.1 - 0.00075 18.4 0.9 0.0011 17.8 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EON95754.1 - 0.0031 16.4 0.9 0.013 14.3 0.2 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EON95754.1 - 0.0037 17.4 0.1 0.0076 16.4 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EON95754.1 - 0.01 15.8 0.8 0.018 15.0 0.5 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EON95754.1 - 0.014 15.4 0.3 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.1 EON95754.1 - 0.015 15.4 1.0 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain ApbA PF02558.11 EON95754.1 - 0.035 13.5 0.3 0.06 12.7 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EON95754.1 - 0.063 13.0 1.1 0.35 10.6 0.6 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EON95754.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EON95754.1 - 0.081 12.5 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EON95755.1 - 3.9e-13 48.8 0.0 7.2e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Xan_ur_permease PF00860.15 EON95756.1 - 4.2e-24 84.7 28.2 5.1e-14 51.5 6.3 3.1 3 0 0 3 3 3 3 Permease family Sulfate_transp PF00916.15 EON95756.1 - 0.0016 17.4 2.5 0.0016 17.4 1.7 2.5 2 1 1 3 3 3 1 Sulfate transporter family Med26 PF08711.6 EON95757.1 - 1.2e-12 47.1 0.0 2.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3348 PF11828.3 EON95757.1 - 0.071 12.5 4.8 0.15 11.4 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Glyco_hydro_61 PF03443.9 EON95758.1 - 4.3e-50 170.5 1.7 5.9e-50 170.0 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sterol_MT_C PF08498.5 EON95760.1 - 1e-27 95.8 0.2 1.8e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EON95760.1 - 3.1e-20 72.4 0.0 6.7e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95760.1 - 3.8e-17 62.2 0.0 5.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON95760.1 - 5.2e-14 52.2 0.0 8.2e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON95760.1 - 2.3e-13 50.3 0.1 5.6e-13 49.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95760.1 - 1.2e-11 45.1 0.0 3.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON95760.1 - 2.5e-11 43.9 0.1 8.6e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EON95760.1 - 1.1e-10 41.0 0.0 1.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EON95760.1 - 1.7e-10 40.3 0.0 2.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EON95760.1 - 1.8e-08 34.4 0.0 4.9e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON95760.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EON95760.1 - 0.00034 20.2 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EON95760.1 - 0.00038 20.0 0.0 0.00069 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EON95760.1 - 0.00045 19.4 0.0 0.00099 18.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EON95760.1 - 0.0005 19.3 0.1 0.0015 17.7 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase RrnaAD PF00398.15 EON95760.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FAM177 PF14774.1 EON95760.1 - 0.014 15.2 0.5 0.064 13.1 0.1 2.0 2 0 0 2 2 2 0 FAM177 family NodS PF05401.6 EON95760.1 - 0.03 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.1 EON95760.1 - 0.05 14.4 0.0 0.21 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 EON95760.1 - 0.053 13.1 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.7 EON95760.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_1 PF00076.17 EON95761.1 - 1.9e-10 40.2 0.0 3.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON95761.1 - 4.4e-10 39.2 0.0 8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON95761.1 - 2.3e-07 30.6 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EON95761.1 - 0.0018 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EON95761.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Brr6_like_C_C PF10104.4 EON95762.1 - 1.4e-38 131.4 0.5 1.8e-38 131.1 0.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Transket_pyr PF02779.19 EON95764.1 - 6.4e-46 156.0 0.0 8.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EON95764.1 - 2.5e-34 117.8 0.1 7.8e-34 116.2 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 EON95764.1 - 0.022 13.4 0.1 0.059 12.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Y_phosphatase3 PF13350.1 EON95765.1 - 4.9e-48 163.4 0.0 7.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EON95765.1 - 4.7e-10 39.4 0.1 9.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EON95765.1 - 4.6e-05 22.8 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EON95765.1 - 0.00087 18.6 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EON95765.1 - 0.022 14.3 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EON95765.1 - 0.09 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Pex16 PF08610.5 EON95766.1 - 3.8e-102 341.7 0.0 4.7e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) bZIP_2 PF07716.10 EON95767.1 - 1e-07 31.6 12.4 1.8e-07 30.8 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EON95767.1 - 0.0028 17.5 15.4 0.0047 16.8 10.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EON95767.1 - 0.051 13.8 11.1 0.092 13.0 7.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Phytase-like PF13449.1 EON95768.1 - 5.6e-27 94.8 0.0 8.3e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EON95768.1 - 0.052 12.4 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated GST_N_3 PF13417.1 EON95769.1 - 1.8e-18 66.5 0.1 3.1e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EON95769.1 - 5e-15 55.2 0.0 1.1e-14 54.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EON95769.1 - 9.7e-12 44.8 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EON95769.1 - 0.00025 20.9 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 EON95769.1 - 0.0032 17.3 0.0 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SWIRM PF04433.12 EON95770.1 - 7.9e-15 54.7 0.0 9.3e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain DUF899 PF05988.7 EON95772.1 - 2.6e-70 236.1 0.0 3.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 EON95772.1 - 4.6e-06 26.3 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EON95772.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF1691 PF07950.6 EON95773.1 - 2.1e-37 127.3 9.2 1.7e-22 79.4 2.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) RskA PF10099.4 EON95773.1 - 0.091 12.4 1.5 0.23 11.1 1.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Herpes_US9 PF06072.6 EON95773.1 - 0.17 11.7 0.4 0.38 10.6 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Aldo_ket_red PF00248.16 EON95774.1 - 1.5e-62 210.9 0.0 1.7e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DAP PF15228.1 EON95774.1 - 0.12 13.1 0.0 0.2 12.4 0.0 1.3 1 0 0 1 1 1 0 Death-associated protein ADH_zinc_N PF00107.21 EON95775.1 - 5.3e-25 87.4 0.4 1.1e-24 86.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95775.1 - 7.7e-21 73.9 0.5 1.4e-20 73.0 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EON95775.1 - 0.00073 20.1 0.2 0.0015 19.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EON95775.1 - 0.0013 19.5 0.5 0.0027 18.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DnaJ PF00226.26 EON95776.1 - 4.2e-20 71.2 2.2 4.2e-20 71.2 1.6 2.6 2 1 0 2 2 2 1 DnaJ domain TraH PF06122.6 EON95776.1 - 0.097 11.4 3.8 0.16 10.7 2.7 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF4551 PF15087.1 EON95776.1 - 0.88 7.8 5.7 1.4 7.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PP-binding PF00550.20 EON95777.1 - 1.9e-06 28.0 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Complex1_LYR PF05347.10 EON95778.1 - 1e-06 28.4 0.1 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EON95778.1 - 1.4e-05 25.1 0.1 1.7e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DSHCT PF08148.7 EON95779.1 - 7.9e-63 210.9 0.4 1.4e-62 210.1 0.3 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EON95779.1 - 7.8e-21 74.2 0.0 2.1e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EON95779.1 - 1.5e-08 34.1 0.2 3.1e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EON95779.1 - 2.7e-06 27.1 0.0 9.9e-06 25.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain API5 PF05918.6 EON95779.1 - 5.1 5.4 8.3 8.2 4.7 5.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2_jaz PF12171.3 EON95780.1 - 1.2e-06 28.4 4.4 1.9e-06 27.8 3.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EON95780.1 - 0.00013 22.0 0.8 0.00021 21.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EON95780.1 - 0.0056 16.9 0.2 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EON95780.1 - 0.018 15.1 0.3 0.029 14.4 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EON95780.1 - 0.033 14.5 1.0 0.06 13.7 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF965 PF06135.7 EON95780.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) MFS_1 PF07690.11 EON95781.1 - 3.7e-30 104.8 8.8 4.2e-30 104.6 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95781.1 - 5e-10 38.5 8.6 9.8e-10 37.5 6.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EON95781.1 - 0.55 8.2 7.5 1.3 6.9 3.4 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_7 PF13508.1 EON95782.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON95782.1 - 1.2e-07 31.5 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EON95782.1 - 4.3e-06 26.3 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EON95782.1 - 2e-05 24.6 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EON95782.1 - 9.3e-05 22.2 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EON95782.1 - 0.0033 17.2 0.3 0.0056 16.5 0.0 1.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase IF3_N PF05198.11 EON95782.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain adh_short PF00106.20 EON95783.1 - 2.4e-14 53.6 0.5 1.1e-10 41.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EON95783.1 - 0.00014 21.7 0.3 0.002 17.9 0.0 2.5 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EON95783.1 - 0.0015 17.8 0.2 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EON95783.1 - 0.017 14.5 0.0 0.84 9.0 0.1 2.1 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON95783.1 - 0.04 13.9 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EON95783.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NADH-u_ox-rdase PF10785.4 EON95784.1 - 4.4e-35 119.7 0.2 7.5e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EON95784.1 - 3.6e-33 113.1 0.1 5.5e-33 112.5 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Snf7 PF03357.16 EON95785.1 - 1.9e-09 37.1 28.4 1.9e-09 37.1 19.7 1.6 2 0 0 2 2 2 1 Snf7 3-dmu-9_3-mt PF06983.8 EON95785.1 - 0.58 10.4 4.6 0.47 10.7 1.7 2.0 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Peptidase_S30 PF01577.11 EON95785.1 - 3.3 7.0 9.6 4.9 6.4 6.7 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease ASL_C PF08328.6 EON95785.1 - 4.2 7.2 10.4 1 9.1 2.8 2.3 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DUF1451 PF07295.6 EON95785.1 - 9 6.0 15.7 3.4 7.4 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) adh_short PF00106.20 EON95786.1 - 4.1e-22 78.8 1.7 3.8e-21 75.7 1.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON95786.1 - 6.2e-17 62.1 0.7 8.9e-17 61.6 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON95786.1 - 6e-08 32.5 2.3 1.4e-07 31.3 0.2 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EON95786.1 - 6.8e-05 22.9 0.2 0.00019 21.5 0.2 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 EON95786.1 - 0.023 14.2 0.1 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EON95786.1 - 0.058 13.3 2.7 0.31 11.0 0.3 2.7 2 2 0 2 2 2 0 NADH(P)-binding Tubulin_C PF03953.12 EON95787.1 - 0.0046 17.0 0.1 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Tropomyosin_1 PF12718.2 EON95787.1 - 0.11 12.3 3.3 6.8 6.5 0.3 2.5 1 1 0 2 2 2 0 Tropomyosin like OEP PF02321.13 EON95788.1 - 0.019 14.5 3.1 0.03 13.9 2.2 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein VacJ PF04333.8 EON95788.1 - 0.087 12.2 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 VacJ like lipoprotein YdfA_immunity PF12127.3 EON95788.1 - 0.18 10.6 6.1 0.22 10.3 4.3 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Bot1p PF12298.3 EON95789.1 - 3.4e-53 180.0 2.2 4.2e-53 179.8 1.2 1.3 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Kinesin-related PF06548.6 EON95789.1 - 0.031 12.8 0.2 0.041 12.4 0.1 1.1 1 0 0 1 1 1 0 Kinesin-related GXWXG PF14231.1 EON95790.1 - 9.3e-25 86.0 0.3 1.4e-24 85.4 0.2 1.3 1 0 0 1 1 1 1 GXWXG protein DUF4334 PF14232.1 EON95790.1 - 8.5e-24 82.9 0.5 8.5e-24 82.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) Myosin_tail_1 PF01576.14 EON95791.1 - 1.5e-20 72.6 69.0 2.6e-20 71.8 47.9 1.2 1 0 0 1 1 1 1 Myosin tail DUF869 PF05911.6 EON95791.1 - 1.9e-07 29.7 58.6 0.0061 14.8 8.0 4.8 1 1 5 6 6 6 6 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EON95791.1 - 2e-07 30.4 30.3 5.3e-05 22.5 5.5 3.4 1 1 2 3 3 3 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 EON95791.1 - 3e-05 22.7 49.9 0.0042 15.6 17.2 2.5 1 1 1 2 2 2 2 AAA domain Filament PF00038.16 EON95791.1 - 9.8e-05 21.9 55.4 0.0042 16.6 8.2 4.0 1 1 3 4 4 4 3 Intermediate filament protein Rootletin PF15035.1 EON95791.1 - 0.00071 19.6 53.8 0.11 12.4 10.8 5.4 1 1 2 3 3 3 2 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EON95791.1 - 0.00091 18.8 72.0 0.48 10.0 15.9 4.8 2 1 1 3 3 2 1 IncA protein Spc7 PF08317.6 EON95791.1 - 0.0013 17.4 58.2 0.045 12.4 8.0 3.9 1 1 5 6 6 6 6 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 EON95791.1 - 0.0014 18.4 32.8 0.016 15.0 7.6 4.8 2 1 5 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 EON95791.1 - 0.0015 18.4 63.5 0.023 14.5 10.8 5.1 1 1 3 5 5 5 3 Autophagy protein 16 (ATG16) WEMBL PF05701.6 EON95791.1 - 0.04 12.3 66.6 0.072 11.5 46.2 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 EON95791.1 - 0.12 12.6 31.9 0.1 12.8 1.0 5.9 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EON95791.1 - 0.29 8.4 55.1 0.12 9.6 27.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EON95791.1 - 0.3 9.9 48.7 0.22 10.4 8.3 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Sec8_exocyst PF04048.9 EON95791.1 - 0.55 9.8 30.5 0.42 10.2 4.3 5.3 1 1 2 4 4 4 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.2 EON95791.1 - 2.4 7.3 56.0 0.2 10.9 12.5 3.8 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain HrpB7 PF09486.5 EON95791.1 - 2.5 8.0 43.0 0.087 12.7 7.9 4.9 2 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.10 EON95791.1 - 2.9 7.8 57.5 0.77 9.7 6.2 4.6 2 1 3 5 5 5 0 Fez1 DUF641 PF04859.7 EON95791.1 - 3.5 7.3 35.9 0.21 11.3 2.1 4.9 2 2 2 5 5 5 0 Plant protein of unknown function (DUF641) CALCOCO1 PF07888.6 EON95791.1 - 3.5 5.7 53.5 1.4 7.0 22.7 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like COG5 PF10392.4 EON95791.1 - 4.2 7.3 29.0 0.42 10.5 4.2 4.1 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Phage_GP20 PF06810.6 EON95791.1 - 6.8 6.1 56.1 0.093 12.1 4.6 4.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 EON95791.1 - 7.2 5.5 61.0 0.88 8.5 13.7 3.9 1 1 3 4 4 4 0 Autophagy protein Apg6 Laminin_II PF06009.7 EON95791.1 - 7.6 6.2 40.9 0.32 10.7 6.8 4.4 1 1 2 4 4 4 0 Laminin Domain II DUF4200 PF13863.1 EON95791.1 - 9.6 6.1 61.3 0.17 11.7 4.4 5.4 1 1 5 6 6 6 0 Domain of unknown function (DUF4200) COG2 PF06148.6 EON95791.1 - 9.9 6.0 37.5 1.2 9.0 1.9 5.6 1 1 5 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 Glyoxalase PF00903.20 EON95793.1 - 1.2e-09 38.1 0.3 5.5e-07 29.6 0.2 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EON95793.1 - 9.1e-05 23.0 0.6 0.0043 17.6 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase-like domain adh_short PF00106.20 EON95794.1 - 1.8e-14 53.9 0.1 2.2e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95794.1 - 2e-09 37.3 0.1 2.6e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON95794.1 - 1.8e-05 24.6 0.0 2e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Med9 PF07544.8 EON95795.1 - 0.0036 17.0 2.0 0.0036 17.0 1.4 4.1 2 1 3 5 5 5 1 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 EON95795.1 - 0.0062 16.3 29.1 0.025 14.4 4.5 3.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) ADIP PF11559.3 EON95795.1 - 0.0065 16.3 10.5 0.0065 16.3 7.2 3.4 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 EON95795.1 - 0.019 14.5 31.4 0.34 10.4 0.4 3.0 1 1 2 3 3 3 0 IncA protein Striatin PF08232.7 EON95795.1 - 0.025 14.8 23.0 0.045 14.0 4.0 3.4 1 1 1 2 2 2 0 Striatin family HR1 PF02185.11 EON95795.1 - 0.034 13.8 0.2 0.034 13.8 0.1 5.0 2 1 3 5 5 5 0 Hr1 repeat Tropomyosin PF00261.15 EON95795.1 - 0.037 13.1 28.4 0.044 12.8 11.4 3.0 1 1 2 3 3 3 0 Tropomyosin DivIVA PF05103.8 EON95795.1 - 0.059 13.4 22.3 8.9 6.3 0.0 3.4 2 1 1 3 3 3 0 DivIVA protein Nsp1_C PF05064.8 EON95795.1 - 0.1 12.2 0.3 0.1 12.2 0.2 3.6 2 1 2 4 4 4 0 Nsp1-like C-terminal region CALCOCO1 PF07888.6 EON95795.1 - 0.22 9.7 25.6 0.036 12.3 13.7 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.3 EON95795.1 - 0.25 10.6 25.3 0.075 12.2 6.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 EON95795.1 - 0.92 9.3 32.2 1.4 8.7 9.7 2.9 1 1 2 3 3 3 0 Tropomyosin like Fib_alpha PF08702.5 EON95795.1 - 2 8.5 14.3 1.5 8.8 2.0 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EON95795.1 - 6.4 5.9 24.4 1.8 7.7 8.9 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding NBP1 PF08537.5 EON95795.1 - 9 5.3 15.1 0.11 11.7 1.3 2.2 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 adh_short PF00106.20 EON95796.1 - 1.3e-20 73.9 0.1 1.3e-19 70.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON95796.1 - 9.1e-17 61.6 0.0 1.5e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON95796.1 - 3e-11 43.3 0.2 1.7e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EON95796.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EON95796.1 - 0.049 13.1 1.2 0.099 12.1 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Glyco_tran_WecB PF03808.8 EON95796.1 - 0.12 11.8 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family WASH-7_C PF14746.1 EON95797.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal ComJ PF11033.3 EON95797.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Competence protein J (ComJ) Aldedh PF00171.17 EON95798.1 - 8.8e-45 152.8 0.0 9.9e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_2 PF07992.9 EON95799.1 - 2.7e-28 99.2 2.2 4.7e-28 98.4 1.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON95799.1 - 1.8e-14 53.9 0.1 1.8e-14 53.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EON95799.1 - 9.6e-14 50.7 0.0 2.9e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EON95799.1 - 5.1e-08 33.2 0.2 0.00033 20.7 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EON95799.1 - 1.3e-05 25.3 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EON95799.1 - 3.9e-05 22.7 0.1 0.072 12.0 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EON95799.1 - 3.9e-05 22.7 0.9 0.042 12.7 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EON95799.1 - 0.013 14.0 2.0 2.1 6.7 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 EON95799.1 - 0.016 15.0 3.2 3 7.6 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EON95799.1 - 0.053 13.7 0.7 7.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding hSH3 PF14603.1 EON95799.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain Glyco_hydro_28 PF00295.12 EON95800.1 - 1.8e-104 349.2 20.5 2.2e-104 348.9 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.4 EON95800.1 - 0.041 13.7 0.4 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) E1-E2_ATPase PF00122.15 EON95801.1 - 5.1e-49 166.3 0.0 7e-48 162.6 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EON95801.1 - 1.5e-39 136.6 0.0 2.5e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EON95801.1 - 2.1e-28 98.2 0.6 8.8e-12 45.0 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EON95801.1 - 5e-17 62.6 0.0 9.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON95801.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Caveolin PF01146.12 EON95801.1 - 0.67 9.5 5.5 0.67 9.5 0.4 2.3 2 0 0 2 2 2 0 Caveolin DAO PF01266.19 EON95802.1 - 2.2e-41 141.9 1.3 2.7e-41 141.6 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EON95802.1 - 1e-12 47.4 0.0 2.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EON95802.1 - 5.4e-09 35.9 0.3 1.2e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EON95802.1 - 1.6e-06 27.4 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EON95802.1 - 2.6e-06 26.5 0.2 3.7e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EON95802.1 - 9.4e-06 25.9 0.2 2.8e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON95802.1 - 4.5e-05 23.5 0.0 0.0032 17.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON95802.1 - 5.9e-05 22.2 0.8 8.4e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EON95802.1 - 6.9e-05 22.1 0.5 0.0031 16.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EON95802.1 - 0.00018 20.6 0.2 0.00059 19.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EON95802.1 - 0.00054 19.8 0.1 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON95802.1 - 0.016 14.1 0.1 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 EON95802.1 - 0.018 14.0 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EON95802.1 - 0.022 13.2 0.1 0.034 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EON95802.1 - 0.061 12.9 0.1 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EON95802.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EON95802.1 - 0.13 12.0 0.1 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding PHA_gran_rgn PF09650.5 EON95802.1 - 0.16 12.0 0.3 1.7 8.7 0.0 2.4 1 1 1 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) ADH_N PF08240.7 EON95803.1 - 9.7e-29 99.3 2.5 2e-28 98.3 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON95803.1 - 4.4e-20 71.5 0.0 6.9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EON95803.1 - 0.019 14.5 0.7 0.032 13.8 0.5 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase POR PF01558.13 EON95803.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Abhydrolase_1 PF00561.15 EON95804.1 - 8e-16 58.2 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EON95804.1 - 5.3e-09 36.3 0.0 1.7e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EON95804.1 - 2.7e-07 30.4 0.0 1.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.2 EON95804.1 - 0.0012 18.5 0.0 0.025 14.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.14 EON95805.1 - 8.6e-51 171.6 0.0 1.3e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EON95805.1 - 0.0013 19.0 0.1 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EON95805.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EON95805.1 - 0.056 12.8 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Ammonium_transp PF00909.16 EON95806.1 - 2.1e-80 270.1 11.0 2.5e-80 269.9 7.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SepZ PF06066.6 EON95806.1 - 0.076 13.0 0.3 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 SepZ Transgly_assoc PF04226.8 EON95806.1 - 3.8 7.6 12.4 0.085 12.9 0.9 3.3 2 1 1 3 3 3 0 Transglycosylase associated protein DUF4229 PF14012.1 EON95806.1 - 6.1 6.8 6.2 5.8 6.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF2589 PF11655.3 EON95807.1 - 0.38 10.8 7.1 0.73 9.9 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) CDC37_N PF03234.9 EON95807.1 - 7.1 6.9 14.4 1.5 9.0 7.0 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Peptidase_M14 PF00246.19 EON95809.1 - 1.5e-57 195.3 0.0 8.9e-32 110.7 0.0 2.2 2 0 0 2 2 2 2 Zinc carboxypeptidase Propep_M14 PF02244.11 EON95809.1 - 0.039 13.6 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Isochorismatase PF00857.15 EON95810.1 - 1.3e-10 41.4 0.0 8.7e-09 35.5 0.0 2.7 2 1 0 2 2 2 2 Isochorismatase family Arginase PF00491.16 EON95811.1 - 1.2e-68 231.3 0.1 1.3e-68 231.2 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EON95811.1 - 0.09 12.9 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 UPF0489 domain p450 PF00067.17 EON95812.1 - 1.1e-75 254.9 0.0 1.4e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EON95813.1 - 4.8e-25 88.1 0.0 5.5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON95813.1 - 0.027 14.4 0.0 0.088 12.8 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Pribosyltran PF00156.22 EON95814.1 - 6.1e-21 74.4 1.9 8.6e-21 73.9 1.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EON95814.1 - 0.033 13.3 0.1 0.093 11.9 0.0 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DUF1144 PF06610.8 EON95814.1 - 0.059 13.1 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1144) Acyl_transf_1 PF00698.16 EON95815.1 - 2.1e-64 217.8 0.0 3.1e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EON95815.1 - 1.1e-57 195.5 0.0 1.6e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EON95815.1 - 3.1e-56 189.9 0.2 2.5e-55 186.9 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EON95815.1 - 2e-45 154.7 0.2 3.3e-43 147.5 0.1 4.1 5 0 0 5 5 5 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EON95815.1 - 9.5e-36 122.2 0.1 2.3e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EON95815.1 - 4.3e-19 68.3 0.0 1.6e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EON95815.1 - 4.2e-15 56.0 0.0 1.3e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON95815.1 - 1e-12 48.0 0.0 2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EON95815.1 - 8.6e-10 39.5 0.0 4.6e-09 37.2 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95815.1 - 6.8e-08 32.2 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EON95815.1 - 1.7e-07 31.3 0.1 6.2e-07 29.5 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EON95815.1 - 3.2e-07 30.9 0.0 2.1e-06 28.3 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95815.1 - 3.3e-07 30.0 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 EON95815.1 - 4.2e-07 29.7 0.0 8.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_11 PF08241.7 EON95815.1 - 2.1e-06 28.1 0.0 9.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON95815.1 - 0.0035 17.6 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EON95815.1 - 0.031 13.6 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 EON95815.1 - 0.095 11.8 0.0 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Acyl_transf_3 PF01757.17 EON95818.1 - 5.8e-29 100.9 14.3 8.4e-29 100.4 9.9 1.3 1 0 0 1 1 1 1 Acyltransferase family DUF418 PF04235.7 EON95818.1 - 0.015 14.9 0.5 0.015 14.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF418) Aldo_ket_red PF00248.16 EON95819.1 - 7.6e-61 205.4 0.0 1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PsbQ PF05757.6 EON95819.1 - 0.044 13.2 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) WSC PF01822.14 EON95820.1 - 3.9e-12 45.9 6.4 2e-11 43.6 4.4 2.3 1 0 0 1 1 1 1 WSC domain Ribonuc_L-PSP PF01042.16 EON95821.1 - 1.4e-17 63.5 0.0 1.8e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 EON95821.1 - 0.091 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NOGCT (NUC087) domain ADH_N PF08240.7 EON95822.1 - 4.6e-16 58.5 0.1 2.2e-15 56.3 0.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON95822.1 - 2.8e-08 33.3 0.1 4.6e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 EON95822.1 - 0.07 11.9 0.1 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EON95822.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein CRAL_TRIO PF00650.15 EON95823.1 - 9.7e-06 25.1 0.1 4.2e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EON95823.1 - 0.0056 16.7 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Dioxygenase_C PF00775.16 EON95824.1 - 5.8e-12 45.2 0.1 9.2e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Pkinase PF00069.20 EON95825.1 - 1.8e-72 243.6 0.0 2.6e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON95825.1 - 7.1e-38 130.1 0.0 1.8e-37 128.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON95825.1 - 0.0001 21.3 0.6 0.39 9.6 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EON95825.1 - 0.01 15.6 0.1 0.15 11.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abi_2 PF07751.6 EON95825.1 - 0.09 12.9 1.1 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Abi-like protein Amidohydro_3 PF07969.6 EON95826.1 - 5.9e-45 154.1 0.8 6.6e-45 154.0 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family DUF844 PF05815.6 EON95826.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) adh_short PF00106.20 EON95827.1 - 4.5e-27 94.9 0.0 6.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95827.1 - 1.6e-14 53.9 0.0 2.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON95827.1 - 1e-05 25.1 0.1 3e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EON95827.1 - 8.8e-05 21.5 0.0 0.00012 21.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EON95827.1 - 0.00052 19.7 1.3 0.00073 19.2 0.3 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EON95827.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EON95827.1 - 0.12 12.4 0.6 0.21 11.6 0.4 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EON95827.1 - 0.16 11.7 1.3 0.67 9.7 0.4 2.0 1 1 1 2 2 2 0 ThiF family p450 PF00067.17 EON95828.1 - 4.4e-30 104.6 0.0 5.3e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.16 EON95829.1 - 1.2e-34 118.4 0.0 2.3e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EON95829.1 - 1.6e-26 92.6 1.6 1.6e-26 92.6 1.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EON95829.1 - 8.6e-09 34.9 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Sugar_tr PF00083.19 EON95830.1 - 4.2e-70 236.5 23.1 5.1e-70 236.3 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95830.1 - 6.5e-17 61.2 30.8 3.9e-15 55.4 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EON95830.1 - 0.53 10.1 7.1 1.7 8.4 0.0 4.3 4 2 1 6 6 6 0 MFS_1 like family RNase_PH PF01138.16 EON95831.1 - 3.6e-34 117.9 0.2 5.4e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EON95831.1 - 0.0063 16.4 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SDH_alpha PF03313.10 EON95831.1 - 0.019 14.0 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Hist_deacetyl PF00850.14 EON95833.1 - 1.7e-76 257.4 0.0 3e-76 256.6 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Fungal_trans PF04082.13 EON95834.1 - 2.3e-21 75.8 0.5 3e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF627 PF04781.7 EON95834.1 - 0.089 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) VCBS PF13517.1 EON95836.1 - 3.1e-26 91.5 38.1 3.5e-11 43.3 1.2 8.0 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EON95836.1 - 4.7e-15 54.7 18.6 0.003 17.1 0.0 6.5 5 0 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EON95836.1 - 6.6e-05 22.4 13.6 0.075 12.4 0.1 6.3 3 2 3 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region Chitin_bind_1 PF00187.14 EON95836.1 - 0.46 10.4 18.1 2 8.4 12.6 2.2 1 0 0 1 1 1 0 Chitin recognition protein COesterase PF00135.23 EON95837.1 - 2.7e-71 240.9 1.1 3.7e-71 240.4 0.8 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF423 PF04241.10 EON95837.1 - 1.6e-19 69.6 0.4 1.6e-19 69.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Abhydrolase_3 PF07859.8 EON95837.1 - 1.2e-13 51.1 0.1 2.4e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON95837.1 - 0.0037 16.5 1.0 0.0071 15.5 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EON95837.1 - 0.037 13.7 0.3 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioredoxin PF00085.15 EON95838.1 - 4.2e-31 106.6 0.1 1.2e-24 86.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EON95838.1 - 1.5e-08 34.8 0.9 4.7e-07 29.9 0.6 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EON95838.1 - 2.7e-07 30.5 0.0 3.9e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EON95838.1 - 9.3e-06 25.6 0.0 0.00095 19.2 0.0 3.3 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EON95838.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.8 EON95838.1 - 0.0069 16.3 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 ERp29, N-terminal domain AhpC-TSA PF00578.16 EON95838.1 - 0.0075 15.9 0.1 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EON95838.1 - 0.077 12.8 0.3 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain DUF2360 PF10152.4 EON95838.1 - 0.35 11.1 7.3 0.87 9.8 0.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) NAD_binding_10 PF13460.1 EON95839.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EON95839.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.11 EON95839.1 - 0.12 12.9 0.1 0.16 12.4 0.1 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 EON95839.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EON95840.1 - 1e-15 57.3 43.3 2.6e-15 56.0 29.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 EON95841.1 - 3.5e-30 104.9 5.7 4.1e-30 104.7 3.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CTV_P6 PF06706.6 EON95841.1 - 1 8.9 6.7 0.89 9.0 1.0 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF4095 PF13338.1 EON95842.1 - 0.029 14.5 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) DUF3970 PF13113.1 EON95842.1 - 0.037 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) WD40 PF00400.27 EON95843.1 - 9.3e-20 69.7 8.6 1.2e-09 37.6 0.2 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EON95843.1 - 0.011 15.4 0.2 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Big_2 PF02368.13 EON95843.1 - 0.05 13.4 0.6 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Me-amine-dh_H PF06433.6 EON95843.1 - 0.13 10.8 0.1 0.57 8.7 0.1 1.9 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) MFS_1 PF07690.11 EON95844.1 - 2.4e-05 23.2 21.2 0.00012 20.9 14.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily IncA PF04156.9 EON95844.1 - 0.088 12.3 0.2 0.088 12.3 0.1 2.3 2 0 0 2 2 2 0 IncA protein DUF3169 PF11368.3 EON95844.1 - 0.66 9.1 0.0 0.66 9.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4131 PF13567.1 EON95844.1 - 3 7.2 6.5 18 4.6 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF605 PF04652.11 EON95845.1 - 7.5e-66 223.0 1.0 8.9e-66 222.8 0.7 1.0 1 0 0 1 1 1 1 Vta1 like FKBP_N PF01346.13 EON95845.1 - 0.98 9.4 4.5 0.19 11.7 0.6 1.6 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase adh_short PF00106.20 EON95847.1 - 1.5e-22 80.2 0.3 2.1e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95847.1 - 8.8e-08 32.0 0.1 1.9e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON95847.1 - 5.1e-07 29.7 0.0 1.5e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Focal_AT PF03623.8 EON95847.1 - 0.12 11.8 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region DUF3236 PF11576.3 EON95847.1 - 0.13 11.6 0.3 0.24 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Pkinase PF00069.20 EON95849.1 - 4.4e-24 85.0 0.0 1.6e-19 70.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EON95849.1 - 7.9e-11 41.5 0.0 0.00016 20.8 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase adh_short PF00106.20 EON95851.1 - 2.5e-28 99.0 0.9 3.1e-28 98.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON95851.1 - 3e-23 82.8 0.0 3.7e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON95851.1 - 1.9e-15 56.9 0.4 3e-15 56.3 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF134 PF02001.11 EON95851.1 - 0.13 12.1 0.4 5.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF134 DIOX_N PF14226.1 EON95852.1 - 1.7e-27 96.2 0.0 2.5e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Epimerase PF01370.16 EON95853.1 - 1.2e-17 64.1 0.0 2.2e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON95853.1 - 9.7e-11 40.8 0.0 1.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EON95853.1 - 2.1e-10 40.9 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EON95853.1 - 2.1e-10 39.9 0.0 2.3e-08 33.3 0.1 2.8 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EON95853.1 - 2.4e-07 30.8 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95853.1 - 5.6e-05 22.8 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EON95853.1 - 0.00063 18.7 0.0 0.00086 18.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EON95853.1 - 0.0051 16.1 0.6 0.017 14.4 0.2 2.0 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EON95853.1 - 0.042 12.7 0.0 0.097 11.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain OPT PF03169.10 EON95854.1 - 2.5e-90 303.7 44.5 2.9e-90 303.4 30.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M14 PF00246.19 EON95855.1 - 4.2e-41 141.3 0.6 6.2e-41 140.8 0.4 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF4231 PF14015.1 EON95856.1 - 0.11 12.5 0.8 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 EON95857.1 - 1e-19 70.5 65.0 1e-13 50.7 27.8 3.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EON95858.1 - 9.1e-37 126.5 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON95858.1 - 1.3e-18 67.0 0.0 3.1e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON95858.1 - 5.2e-06 25.6 0.0 9.6e-06 24.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EON95858.1 - 0.04 13.6 0.1 0.18 11.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1399 PF07173.7 EON95860.1 - 1.5e-19 70.6 0.8 3.8e-15 56.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) zf-CSL PF05207.8 EON95860.1 - 0.11 12.0 0.2 16 5.1 0.0 2.4 2 0 0 2 2 2 0 CSL zinc finger FAD_binding_4 PF01565.18 EON95861.1 - 1.9e-22 79.2 1.0 3e-22 78.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON95861.1 - 0.07 13.0 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like GMC_oxred_C PF05199.8 EON95862.1 - 8.7e-26 90.9 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EON95862.1 - 9.2e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase PDR_CDR PF06422.7 EON95863.1 - 6.5e-32 109.2 0.0 1.1e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 EON95863.1 - 1.6e-17 64.0 0.0 2.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EON95863.1 - 3.3e-05 23.9 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EON95863.1 - 0.00014 21.3 0.4 0.00027 20.3 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON95863.1 - 0.00031 20.7 0.4 0.00057 19.9 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EON95863.1 - 0.00036 20.4 0.1 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EON95863.1 - 0.00045 19.4 0.0 0.00064 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 EON95863.1 - 0.00051 19.2 2.4 0.00051 19.2 0.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.14 EON95863.1 - 0.00092 18.5 0.0 0.052 12.7 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EON95863.1 - 0.0024 17.3 0.1 0.0049 16.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 EON95863.1 - 0.0027 17.1 0.1 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EON95863.1 - 0.0055 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON95863.1 - 0.011 16.5 0.0 0.026 15.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON95863.1 - 0.048 13.7 0.2 0.099 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EON95863.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Acetyltransf_3 PF13302.1 EON95864.1 - 1.3e-14 54.5 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON95864.1 - 9.8e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EON95864.1 - 6.8e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EON95864.1 - 0.00059 19.7 0.0 0.00073 19.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EON95864.1 - 0.00075 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FMN_red PF03358.10 EON95865.1 - 1.6e-32 112.1 0.0 2.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EON95865.1 - 6.7e-09 35.5 0.0 9.8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Adeno_E3B PF03376.9 EON95866.1 - 0.36 10.7 5.5 0.48 10.3 3.8 1.2 1 0 0 1 1 1 0 Adenovirus E3B protein Methyltransf_2 PF00891.13 EON95867.1 - 2e-30 105.8 0.0 3.4e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Fe-ADH_2 PF13685.1 EON95867.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase NIF PF03031.13 EON95868.1 - 1.2e-36 125.7 0.0 1.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PMSR PF01625.16 EON95870.1 - 3.8e-60 202.3 1.9 4.7e-60 202.0 1.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sugar_tr PF00083.19 EON95871.1 - 1.3e-81 274.5 16.9 1.5e-81 274.3 11.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95871.1 - 2e-32 112.3 43.0 1.7e-29 102.6 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EON95871.1 - 0.13 12.3 2.1 0.35 10.9 1.5 1.7 1 0 0 1 1 1 0 Phage holin family 2 Pro_dh PF01619.13 EON95872.1 - 3.4e-34 118.2 0.0 8.3e-34 116.9 0.0 1.6 1 1 0 1 1 1 1 Proline dehydrogenase SnoaL PF07366.7 EON95873.1 - 4.1e-12 45.7 0.0 8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Metallophos PF00149.23 EON95873.1 - 8.1e-09 35.1 1.2 3.3e-08 33.1 0.4 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase SnoaL_2 PF12680.2 EON95873.1 - 3e-06 27.5 0.1 9.6e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain Chromate_transp PF02417.10 EON95874.1 - 0.036 13.6 6.6 0.11 12.1 2.2 2.2 2 0 0 2 2 2 0 Chromate transporter Sugar_tr PF00083.19 EON95875.1 - 1.5e-92 310.5 27.3 1.7e-92 310.3 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95875.1 - 2.9e-18 65.7 27.2 2.9e-18 65.7 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EON95875.1 - 0.083 12.3 3.2 1.8 8.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 EON95876.1 - 8.8e-41 139.7 27.5 8.8e-41 139.7 19.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95876.1 - 4e-15 55.3 19.4 5.9e-15 54.7 13.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EON95876.1 - 0.00095 18.9 1.4 0.0033 17.1 1.0 2.0 1 0 0 1 1 1 1 MFS_1 like family UNC-93 PF05978.11 EON95876.1 - 0.0034 16.8 1.7 0.0034 16.8 1.2 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MatE PF01554.13 EON95877.1 - 1.4e-45 154.7 34.4 1.4e-31 109.3 6.7 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EON95877.1 - 7.7e-05 22.5 4.5 7.7e-05 22.5 3.1 4.2 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Bax1-I PF01027.15 EON95878.1 - 3.5e-30 105.1 11.1 3.5e-30 105.1 7.7 1.7 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 EON95881.1 - 1.5e-11 43.6 12.2 1.7e-11 43.4 8.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95881.1 - 3.6e-08 32.4 0.0 3.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cactin_mid PF10312.4 EON95882.1 - 2.1e-64 216.3 6.6 3e-64 215.8 4.6 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EON95882.1 - 2.2e-55 185.5 4.8 4.2e-55 184.6 3.3 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EON95882.1 - 0.00099 18.9 7.1 0.077 12.9 0.4 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1087) MFS_1 PF07690.11 EON95883.1 - 4e-09 35.6 6.3 2.9e-08 32.8 1.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 EON95884.1 - 1.2e-29 103.5 0.1 1.4e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.19 EON95885.1 - 6.3e-54 183.2 5.2 7.9e-54 182.9 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95885.1 - 1.4e-11 43.7 9.8 1.4e-11 43.7 6.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 EON95885.1 - 0.65 8.8 8.6 1.1 8.0 6.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Glyco_hydro_28 PF00295.12 EON95886.1 - 4.8e-49 167.0 4.6 9.1e-49 166.1 3.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 RPE65 PF03055.10 EON95887.1 - 5.1e-114 381.5 0.0 5.7e-114 381.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GFO_IDH_MocA PF01408.17 EON95888.1 - 7e-19 68.5 0.1 1.3e-18 67.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EON95888.1 - 0.0032 17.8 0.0 0.0099 16.2 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EON95888.1 - 0.026 14.9 0.0 0.074 13.4 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Aldo_ket_red PF00248.16 EON95889.1 - 8.9e-64 215.0 0.0 1e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EON95891.1 - 1e-14 54.0 0.1 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EON95892.1 - 1.1e-19 70.3 20.6 2.5e-13 49.4 9.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BSP PF04450.7 EON95892.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Peptidase of plants and bacteria DUF2371 PF10177.4 EON95892.1 - 0.098 12.5 0.3 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF1228 PF06779.9 EON95892.1 - 0.26 11.3 3.2 3.2 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) FtsH_ext PF06480.10 EON95892.1 - 0.39 10.9 2.1 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 FtsH Extracellular Phage_holin_5 PF06946.6 EON95892.1 - 3.9 7.7 8.6 1.9 8.6 0.5 2.4 2 0 0 2 2 2 0 Phage holin Bac_rhamnosid PF05592.6 EON95893.1 - 4e-98 328.8 0.0 4.6e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase LANC_like PF05147.8 EON95893.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein cNMP_binding PF00027.24 EON95894.1 - 2.7e-36 123.2 0.0 1.8e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_3 PF05899.7 EON95894.1 - 0.12 11.7 0.1 9.4 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sugar_tr PF00083.19 EON95895.1 - 1.7e-114 382.9 24.2 1.9e-114 382.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95895.1 - 2.8e-25 88.7 29.1 1.1e-16 60.5 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.1 EON95896.1 - 3.1e-59 200.6 56.6 3.8e-59 200.3 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON95896.1 - 2e-28 99.0 47.9 2.9e-28 98.4 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EON95897.1 - 2.5e-17 62.6 0.0 5.1e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON95897.1 - 6.6e-11 43.1 0.0 1.1e-10 42.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95897.1 - 0.00038 20.1 0.1 0.02 14.6 0.0 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CGI-121 PF08617.5 EON95898.1 - 2.8e-46 157.1 0.0 3.2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Zeta_toxin PF06414.7 EON95898.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Atg14 PF10186.4 EON95899.1 - 6.1e-19 68.0 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EON95899.1 - 0.00014 21.0 1.6 0.00091 18.3 1.1 2.1 1 1 0 1 1 1 1 Autophagy protein Apg6 DUF2630 PF10944.3 EON95899.1 - 0.08 13.0 4.6 0.17 12.0 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) IncA PF04156.9 EON95899.1 - 0.6 9.6 6.1 1.1 8.8 4.2 1.3 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 EON95900.1 - 6.7e-59 199.6 29.3 8.3e-59 199.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95900.1 - 2.1e-12 46.4 39.9 3.9e-12 45.5 24.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm15 PF15590.1 EON95900.1 - 0.15 11.1 0.1 0.69 9.0 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 15 FAD_binding_7 PF03441.9 EON95901.1 - 3.3e-103 344.6 0.2 5.9e-103 343.8 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EON95901.1 - 2.6e-39 134.6 0.0 4.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EON95901.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family Tim17 PF02466.14 EON95902.1 - 0.23 11.5 5.0 0.76 9.8 1.7 2.2 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EON95902.1 - 0.25 11.5 2.6 0.89 9.7 0.8 2.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TRI12 PF06609.8 EON95903.1 - 9e-22 77.0 4.6 1e-21 76.7 3.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON95904.1 - 1.9e-10 40.0 17.3 2.3e-10 39.7 12.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 EON95905.1 - 2.2e-09 37.0 11.2 3.4e-09 36.4 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EON95905.1 - 0.11 10.5 3.0 0.15 10.1 2.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aldedh PF00171.17 EON95906.1 - 2.1e-119 398.8 0.0 2.3e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EON95906.1 - 0.0055 15.4 0.0 0.14 10.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) MFS_1 PF07690.11 EON95907.1 - 4.5e-31 107.8 24.5 4.5e-31 107.8 17.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PhaG_MnhG_YufB PF03334.9 EON95907.1 - 0.016 15.2 4.4 4.8 7.2 0.0 3.6 2 1 1 3 3 3 0 Na+/H+ antiporter subunit Nucleopor_Nup85 PF07575.8 EON95907.1 - 0.1 10.7 0.5 0.16 10.1 0.4 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Ribosomal_S21e PF01249.13 EON95908.1 - 5.6e-42 141.5 0.1 6.2e-42 141.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e p450 PF00067.17 EON95909.1 - 1.9e-52 178.3 0.0 6.5e-46 156.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Med31 PF05669.7 EON95910.1 - 8.1e-38 128.3 1.1 9e-38 128.1 0.8 1.0 1 0 0 1 1 1 1 SOH1 DUF3166 PF11365.3 EON95911.1 - 5.8 7.4 14.3 0.71 10.3 0.7 4.3 2 1 2 5 5 5 0 Protein of unknown function (DUF3166) DUF501 PF04417.7 EON95911.1 - 7.3 6.4 10.4 1.1 9.0 0.5 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF501) DUF4201 PF13870.1 EON95912.1 - 0.0068 15.8 2.2 0.0068 15.8 1.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) Filament PF00038.16 EON95912.1 - 0.011 15.2 33.6 0.058 12.8 12.5 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.3 EON95912.1 - 0.1 9.8 33.8 0.12 9.6 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Vac_Fusion PF02346.11 EON95912.1 - 0.22 10.9 3.4 32 4.0 0.0 4.1 4 0 0 4 4 4 0 Chordopoxvirus fusion protein TPR_MLP1_2 PF07926.7 EON95912.1 - 0.31 10.7 40.9 0.35 10.6 11.5 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein KIAA1430 PF13879.1 EON95912.1 - 0.8 10.1 10.2 16 6.0 7.0 2.7 1 1 0 1 1 1 0 KIAA1430 homologue BEX PF04538.7 EON95912.1 - 1.2 9.4 9.8 0.1 12.8 1.0 2.6 1 1 1 2 2 2 0 Brain expressed X-linked like family Bacillus_HBL PF05791.6 EON95912.1 - 1.7 7.9 17.1 1.6 8.0 0.8 3.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 EON95912.1 - 2.4 8.0 19.1 1.6 8.5 4.1 3.8 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 EON95912.1 - 2.4 7.2 14.7 1.3 8.1 0.4 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TMPIT PF07851.8 EON95912.1 - 2.6 7.0 18.8 1.3 8.0 4.9 2.3 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.1 EON95912.1 - 2.8 7.0 30.6 0.35 10.0 10.4 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding IZUMO PF15005.1 EON95912.1 - 5.6 7.0 6.8 2.5 8.1 2.4 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion DUF972 PF06156.8 EON95912.1 - 6.2 7.2 22.7 0.75 10.1 2.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EON95912.1 - 6.7 6.6 33.4 1.8 8.4 8.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4148 PF13663.1 EON95912.1 - 9.2 6.2 9.3 8.1 6.3 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4148) DUF724 PF05266.9 EON95912.1 - 9.8 5.7 21.7 8 6.0 6.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) RTC PF01137.16 EON95913.1 - 2.2e-33 114.9 0.0 4.8e-32 110.5 0.0 2.1 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EON95913.1 - 0.044 13.7 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3778 PF12620.3 EON95913.1 - 0.061 12.8 0.0 0.43 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) DUF3754 PF12576.3 EON95913.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) adh_short PF00106.20 EON95914.1 - 2.9e-07 30.5 0.0 7.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 EON95914.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Myosin_head PF00063.16 EON95916.1 - 1.4e-248 826.5 0.3 5.4e-248 824.5 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EON95916.1 - 3.3e-28 97.9 267.9 9.1e-24 83.2 78.2 6.3 2 2 3 5 5 5 5 Myosin tail Myosin_N PF02736.14 EON95916.1 - 1.1e-05 24.9 0.0 3.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EON95916.1 - 0.068 12.9 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ComZ PF10815.3 EON95917.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 ComZ DUF619 PF04768.8 EON95918.1 - 9.3e-51 171.6 0.2 2e-50 170.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EON95918.1 - 1.3e-28 99.7 0.0 4.9e-28 97.8 0.0 2.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EON95918.1 - 1e-24 87.3 0.0 2.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Hexokinase_2 PF03727.11 EON95919.1 - 2.4e-62 210.3 0.0 3.9e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EON95919.1 - 5.1e-62 208.8 0.0 9.9e-62 207.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Metallophos_2 PF12850.2 EON95920.1 - 3.2e-11 43.2 0.0 3e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EON95920.1 - 2e-08 33.8 1.9 3.4e-07 29.8 1.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_A22B PF04258.8 EON95921.1 - 2.9e-49 168.1 10.6 1.2e-47 162.8 7.4 2.7 1 1 0 1 1 1 1 Signal peptide peptidase Arb2 PF09757.4 EON95924.1 - 4.3e-22 78.3 0.0 8.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Pro-kuma_activ PF09286.6 EON95925.1 - 2e-46 157.5 1.2 3.1e-46 156.9 0.4 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EON95925.1 - 1.7e-08 33.9 3.6 3.2e-08 33.0 2.5 1.4 1 0 0 1 1 1 1 Subtilase family QRPTase_C PF01729.14 EON95926.1 - 4.1e-54 182.6 0.1 5e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EON95926.1 - 1.3e-21 76.2 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 EON95926.1 - 0.0038 16.8 0.1 0.0054 16.3 0.1 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF1341 PF07071.6 EON95926.1 - 0.037 13.5 0.4 0.11 11.9 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1341) IGPS PF00218.16 EON95926.1 - 0.048 12.6 0.1 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase 4HBT_3 PF13622.1 EON95927.1 - 6.3e-33 114.5 1.5 8e-33 114.2 1.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EON95927.1 - 2.4e-11 43.3 0.0 7.8e-05 22.3 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Thaumatin PF00314.12 EON95928.1 - 4.6e-62 209.2 2.6 5.6e-62 208.9 1.8 1.1 1 0 0 1 1 1 1 Thaumatin family B_lectin PF01453.19 EON95929.1 - 7e-06 25.9 0.5 7.1e-05 22.6 0.1 2.3 1 1 0 2 2 2 1 D-mannose binding lectin adh_short PF00106.20 EON95930.1 - 2.9e-13 50.0 2.1 4.4e-13 49.4 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95930.1 - 1.2e-06 28.3 0.9 1.6e-06 27.9 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON95930.1 - 0.028 14.4 0.3 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding adh_short_C2 PF13561.1 EON95930.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Oxysterol_BP PF01237.13 EON95931.1 - 1.4e-128 428.3 0.0 5.1e-128 426.5 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank PF00023.25 EON95931.1 - 3.4e-19 67.6 0.1 2.7e-07 30.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EON95931.1 - 2.7e-18 66.1 0.0 2.1e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EON95931.1 - 2e-17 62.7 0.9 4.3e-10 39.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON95931.1 - 4.4e-17 62.1 0.3 7.6e-09 35.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON95931.1 - 1.4e-13 49.6 0.0 0.0012 18.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 EON95931.1 - 1.6e-12 47.5 0.5 4.3e-12 46.1 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EON95931.1 - 5e-08 32.9 0.6 1.2e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Annexin PF00191.15 EON95932.1 - 1.4e-20 72.9 0.0 1.5e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 Annexin Acetyltransf_1 PF00583.19 EON95933.1 - 2.3e-07 30.7 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EON95933.1 - 0.054 13.6 0.1 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Late_protein_L2 PF00513.13 EON95933.1 - 0.074 11.9 4.2 0.11 11.2 2.9 1.3 1 0 0 1 1 1 0 Late Protein L2 Nop14 PF04147.7 EON95934.1 - 0.0012 16.8 3.0 0.0016 16.4 2.1 1.1 1 0 0 1 1 1 1 Nop14-like family ORC6 PF05460.8 EON95934.1 - 0.58 9.1 13.9 0.86 8.6 9.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sgf11 PF08209.6 EON95934.1 - 1.5 8.1 7.5 0.19 11.0 2.2 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF791 PF05631.9 EON95935.1 - 5.2e-65 219.4 6.7 7.3e-65 218.9 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EON95935.1 - 1.7e-15 56.6 23.8 3.3e-15 55.6 16.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 EON95936.1 - 3.1e-11 43.4 0.0 6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EON95936.1 - 2.4e-09 36.5 0.0 0.01 15.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EON95936.1 - 3.6e-08 32.8 0.0 0.019 15.1 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EON95936.1 - 8.1e-08 32.5 0.2 0.00082 19.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON95936.1 - 3e-06 27.2 0.1 0.2 11.9 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Radical_SAM PF04055.16 EON95937.1 - 6.4e-13 49.2 0.0 9.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pro_isomerase PF00160.16 EON95938.1 - 1.2e-52 178.1 0.0 1.4e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.23 EON95939.1 - 2.5e-84 283.1 0.0 3.1e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON95939.1 - 5.1e-18 65.7 0.0 1.2e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EON95940.1 - 7.1e-17 60.5 4.6 5e-05 23.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EON95940.1 - 0.0041 17.3 0.6 1.2 9.5 0.0 4.0 3 1 1 4 4 4 1 PQQ-like domain ACPS PF01648.15 EON95941.1 - 5e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RRM_6 PF14259.1 EON95941.1 - 0.13 12.2 0.0 12 5.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Synaptobrevin PF00957.16 EON95943.1 - 9.5e-34 114.8 1.0 1.1e-33 114.7 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin ThiF PF00899.16 EON95944.1 - 1.4e-35 122.0 0.0 2.6e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EON95944.1 - 0.00025 20.1 0.2 0.0004 19.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 EON95944.1 - 0.0011 18.1 0.0 0.0021 17.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 ApbA PF02558.11 EON95944.1 - 0.025 14.0 0.3 0.1 12.0 0.2 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MAF_flag10 PF01973.13 EON95944.1 - 0.047 13.2 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF115 TrkA_N PF02254.13 EON95944.1 - 0.076 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EON95944.1 - 0.085 12.2 0.2 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EON95944.1 - 0.11 12.7 0.1 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1620 PF07774.8 EON95945.1 - 3e-70 235.8 0.0 5.8e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EON95945.1 - 1.2e-17 64.2 11.0 6.6e-15 55.2 2.5 2.9 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EON95945.1 - 2.9e-08 32.8 3.9 0.00012 21.4 0.0 5.3 6 0 0 6 6 6 2 PQQ enzyme repeat zf-C3H1 PF10650.4 EON95947.1 - 2.1e-05 23.8 4.1 3.7e-05 23.0 2.9 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain zf-CCCH PF00642.19 EON95947.1 - 0.017 14.7 0.2 0.028 14.0 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIS_C PF01096.13 EON95948.1 - 2.4e-21 75.0 2.7 2.4e-21 75.0 1.9 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EON95948.1 - 7.7e-09 35.0 0.4 7.7e-09 35.0 0.3 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EON95948.1 - 0.0061 16.3 6.0 0.44 10.4 0.2 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 EON95948.1 - 0.016 15.1 4.8 0.18 11.7 0.1 2.4 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) IBR PF01485.16 EON95948.1 - 0.029 14.2 9.2 0.61 10.0 0.2 2.8 2 1 0 2 2 2 0 IBR domain Elf1 PF05129.8 EON95948.1 - 0.042 13.5 2.3 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 EON95948.1 - 0.049 13.0 0.3 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain C1_4 PF07975.7 EON95948.1 - 0.13 12.3 5.4 3.1 7.8 0.1 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Desulfoferrod_N PF06397.7 EON95948.1 - 0.15 11.4 2.3 1.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_4 PF13717.1 EON95948.1 - 0.24 11.1 10.4 1.9 8.2 0.8 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EON95948.1 - 0.25 10.9 9.8 1.4 8.5 0.5 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EON95948.1 - 0.47 10.3 6.3 0.98 9.2 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 EON95948.1 - 0.86 9.9 3.4 3.6 7.9 0.4 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain PhnA_Zn_Ribbon PF08274.7 EON95948.1 - 1.3 8.8 4.6 14 5.5 0.2 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon C1_3 PF07649.7 EON95948.1 - 2.4 8.2 5.0 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 C1-like domain zf-H2C2_2 PF13465.1 EON95948.1 - 3.6 8.0 13.4 1.9 8.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Nudix_N_2 PF14803.1 EON95948.1 - 5.2 6.8 6.2 12 5.7 1.4 2.7 2 1 0 2 2 2 0 Nudix N-terminal DUF4379 PF14311.1 EON95948.1 - 8.9 6.2 8.0 0.41 10.4 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4379) Gly_transf_sug PF04488.10 EON95949.1 - 9.4e-14 51.6 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HSP70 PF00012.15 EON95950.1 - 1.5e-11 42.9 0.4 7.3e-10 37.3 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EON95950.1 - 0.0032 17.0 0.1 0.0073 15.9 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EON95950.1 - 0.019 13.5 0.1 0.12 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein CFEM PF05730.6 EON95951.1 - 7.7e-11 41.6 11.2 1.5e-10 40.7 7.8 1.5 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.6 EON95951.1 - 7.7 4.4 7.8 9.1 4.2 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_3 PF07859.8 EON95952.1 - 4e-58 196.4 0.3 5.1e-58 196.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EON95952.1 - 2.6e-13 49.3 0.0 4.4e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EON95952.1 - 4.4e-07 29.7 0.1 6.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EON95952.1 - 1.3e-06 27.7 0.0 3.1e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EON95952.1 - 3.3e-06 26.1 0.6 1.5e-05 23.9 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EON95952.1 - 0.00018 21.0 0.0 0.048 13.1 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EON95952.1 - 0.00071 19.8 0.1 0.0024 18.1 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S15 PF02129.13 EON95952.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3844 PF12955.2 EON95954.1 - 1.4e-32 111.8 1.0 2.1e-32 111.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_3 PF12947.2 EON95954.1 - 0.36 10.8 7.7 0.7 9.8 5.4 1.5 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.8 EON95954.1 - 2 8.6 7.9 8.4 6.6 5.5 2.0 1 1 0 1 1 1 0 EGF-like domain Zn_clus PF00172.13 EON95955.1 - 1.5e-10 40.8 12.2 2.9e-10 39.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EON95955.1 - 4.7e-07 28.9 0.2 6.8e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EON95956.1 - 9.8e-35 119.8 34.2 1.2e-34 119.5 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EON95956.1 - 0.0051 17.1 0.2 0.013 15.9 0.2 1.6 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.19 EON95956.1 - 0.13 10.7 28.8 0.54 8.7 19.9 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1228 PF06779.9 EON95956.1 - 0.71 9.9 6.8 0.27 11.2 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Vps8 PF12816.2 EON95957.1 - 3.6e-75 251.5 0.2 3.8e-74 248.2 0.0 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EON95957.1 - 8.5e-05 22.1 0.2 0.8 9.2 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF937 PF06078.6 EON95957.1 - 0.051 13.8 0.6 0.13 12.4 0.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Peptidase_M28 PF04389.12 EON95958.1 - 1.5e-33 116.0 0.0 2.3e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EON95958.1 - 4.1e-16 58.5 0.0 9.1e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 PA domain ENTH PF01417.15 EON95959.1 - 2.9e-47 159.6 0.2 4e-47 159.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EON95959.1 - 7e-05 21.6 0.1 9.5e-05 21.2 0.1 1.1 1 0 0 1 1 1 1 ANTH domain LSM PF01423.17 EON95960.1 - 9.2e-19 66.7 0.3 1.1e-18 66.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain Sugar_tr PF00083.19 EON95961.1 - 5.7e-93 311.9 21.6 1.6e-86 290.7 11.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter PrpF PF04303.8 EON95961.1 - 9.5e-42 143.0 0.0 2e-40 138.6 0.0 2.1 2 0 0 2 2 2 1 PrpF protein MFS_1 PF07690.11 EON95961.1 - 3e-27 95.2 25.3 7.3e-27 94.0 17.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SecE PF00584.15 EON95961.1 - 0.031 13.8 4.0 0.031 13.8 0.0 2.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex adh_short PF00106.20 EON95962.1 - 5.3e-20 71.9 3.6 6.9e-20 71.6 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95962.1 - 7.4e-10 38.7 3.3 1.7e-09 37.5 2.3 1.6 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.9 EON95962.1 - 0.045 12.2 0.5 0.077 11.4 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.14 EON95963.1 - 1.3e-63 215.0 0.0 5e-63 213.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EON95963.1 - 1.6e-24 87.0 0.0 4e-24 85.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON95963.1 - 6.8e-11 41.6 0.0 2.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EON95963.1 - 1.8e-10 41.0 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON95963.1 - 2e-07 30.2 0.2 0.078 11.8 0.0 4.0 3 1 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON95963.1 - 6.5e-05 23.2 0.0 0.22 11.9 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON95963.1 - 0.00016 21.4 0.1 0.032 13.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EON95963.1 - 0.00019 21.3 0.1 0.00067 19.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EON95963.1 - 0.00022 21.3 0.4 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EON95963.1 - 0.00043 19.4 0.1 0.28 10.1 0.1 3.0 2 1 1 3 3 3 1 FAD binding domain ThiF PF00899.16 EON95963.1 - 0.0013 18.5 1.1 0.33 10.7 0.2 2.8 3 0 0 3 3 2 1 ThiF family 2-Hacid_dh_C PF02826.14 EON95963.1 - 0.0031 16.7 0.2 0.54 9.3 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EON95963.1 - 0.0034 17.5 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding ApbA PF02558.11 EON95963.1 - 0.0059 16.0 0.0 0.41 10.0 0.0 2.6 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EON95963.1 - 0.0082 15.2 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 EON95963.1 - 0.056 13.0 0.1 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 EON95963.1 - 0.11 11.9 0.2 7.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain UNC-93 PF05978.11 EON95964.1 - 1.7e-15 56.8 9.5 4.7e-15 55.4 6.6 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EON95964.1 - 3.5e-15 55.5 31.6 3.5e-15 55.5 21.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EON95965.1 - 8.9e-17 60.8 14.3 8.9e-17 60.8 9.9 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON95965.1 - 8e-11 41.1 1.7 8e-11 41.1 1.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter ASCH PF04266.9 EON95966.1 - 2e-09 37.7 0.0 2.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 ASCH domain PTR2 PF00854.16 EON95967.1 - 1.2e-41 142.7 12.5 3.6e-40 137.9 8.7 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EON95967.1 - 9.5e-12 44.2 22.1 4.5e-10 38.7 13.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EON95968.1 - 2.9e-22 79.7 0.0 1.1e-21 77.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON95968.1 - 9.6e-16 57.0 0.1 9.2e-13 47.2 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EON95968.1 - 2.3e-09 36.6 0.0 6.5e-06 25.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3Beta_HSD PF01073.14 EON95968.1 - 2.9e-09 36.0 0.0 5.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.1 EON95968.1 - 3.8e-09 36.4 0.0 3.8e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.1 EON95968.1 - 4.2e-08 33.3 0.5 2.8e-07 30.7 0.1 2.6 3 1 0 3 3 3 1 NADH(P)-binding NAD_binding_4 PF07993.7 EON95968.1 - 1.9e-07 30.2 0.0 3.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Pyr_redox_2 PF07992.9 EON95968.1 - 4.1e-05 23.5 0.0 0.0003 20.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON95968.1 - 0.0014 17.6 1.4 0.011 14.6 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EON95968.1 - 0.062 13.0 0.1 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.20 EON95968.1 - 0.077 12.9 0.4 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.1 EON95969.1 - 5.5e-34 118.0 0.3 6.3e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON95969.1 - 1.4e-29 103.1 1.5 1.9e-29 102.7 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON95969.1 - 3.2e-14 53.0 0.2 5.6e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EON95969.1 - 0.0081 15.8 0.5 0.012 15.2 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EON95969.1 - 0.014 15.2 1.9 0.087 12.6 0.5 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YjeF_N PF03853.10 EON95969.1 - 0.024 14.2 0.3 0.043 13.4 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Cas_Cas02710 PF09670.5 EON95969.1 - 0.15 10.6 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) ADH_zinc_N PF00107.21 EON95970.1 - 2e-14 53.2 0.0 3.6e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON95970.1 - 7.6e-11 42.9 0.0 1.6e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON95970.1 - 1.9e-06 27.5 0.1 4.9e-05 23.0 0.0 2.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EON95970.1 - 0.1 12.4 2.2 0.24 11.2 1.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NTR2 PF15458.1 EON95972.1 - 5.2e-70 235.5 15.7 7.3e-70 235.1 10.9 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 CMAS PF02353.15 EON95973.1 - 1.6e-62 211.0 0.1 1.9e-62 210.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EON95973.1 - 9.4e-13 48.1 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON95973.1 - 2.3e-09 37.6 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON95973.1 - 1.5e-07 31.8 0.0 2.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON95973.1 - 3.3e-07 30.8 0.0 1.3e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON95973.1 - 3.5e-07 29.9 0.0 5.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON95973.1 - 2.2e-05 24.4 0.0 7.7e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON95973.1 - 3.5e-05 24.1 0.0 7.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EON95973.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EON95973.1 - 0.0028 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EON95973.1 - 0.042 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EON95973.1 - 0.05 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EON95973.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 EON95973.1 - 0.14 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MARVEL PF01284.18 EON95974.1 - 4.8e-05 23.2 13.6 0.0004 20.2 9.5 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.9 EON95974.1 - 0.32 10.8 6.7 0.2 11.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) CbiQ PF02361.11 EON95974.1 - 0.49 9.9 7.1 0.86 9.1 4.7 1.5 1 1 1 2 2 2 0 Cobalt transport protein DUF4231 PF14015.1 EON95974.1 - 4.3 7.3 6.6 2.8 7.9 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Beta-lactamase PF00144.19 EON95975.1 - 1.7e-30 106.1 0.6 2.6e-30 105.5 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.19 EON95976.1 - 7e-09 35.6 0.1 9.8e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON95976.1 - 8.1e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON95976.1 - 0.0011 19.1 0.1 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EON95976.1 - 0.0024 17.8 0.0 0.0029 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EON95979.1 - 2.3e-07 29.8 25.9 2.3e-07 29.8 18.0 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON95979.1 - 4.9e-06 26.1 2.0 4.9e-06 26.1 1.4 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EON95980.1 - 6.4e-89 298.5 17.4 7.2e-89 298.4 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95980.1 - 1.3e-29 103.0 13.1 1.3e-29 103.0 9.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DsbD PF02683.10 EON95980.1 - 1.5 8.3 8.8 0.093 12.3 0.2 2.7 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Pro_isomerase PF00160.16 EON95981.1 - 2.6e-41 141.3 0.2 3e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HMG-CoA_red PF00368.13 EON95982.1 - 4e-154 512.7 1.8 5.3e-154 512.3 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EON95982.1 - 8.8e-48 161.8 2.2 1.6e-47 161.0 1.5 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EON95982.1 - 1.9e-12 46.8 5.4 1.3e-11 44.1 3.8 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EON95982.1 - 2.2e-05 22.6 4.7 2.2e-05 22.6 3.3 1.5 2 0 0 2 2 2 1 Patched family DUF2198 PF09964.4 EON95982.1 - 0.055 13.2 2.8 0.063 13.0 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF1729 PF08354.5 EON95982.1 - 0.068 12.9 0.4 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) DUF1034 PF06280.7 EON95983.1 - 0.051 13.9 4.5 0.17 12.3 0.0 3.1 3 0 0 3 3 3 0 Fn3-like domain (DUF1034) Glyco_hydro_2_C PF02836.12 EON95984.1 - 1.6e-106 355.5 0.0 2.2e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EON95984.1 - 7.3e-50 168.7 0.3 1.2e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EON95984.1 - 9.7e-46 155.9 0.0 1.6e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EON95984.1 - 1.5e-15 57.5 0.1 3.1e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.10 EON95984.1 - 0.018 14.1 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase Sugar_tr PF00083.19 EON95985.1 - 1.4e-70 238.1 24.8 1.6e-70 237.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON95985.1 - 6.6e-22 77.6 29.0 5.8e-15 54.8 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON95985.1 - 0.0004 18.7 1.8 0.0004 18.7 1.2 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PEP_mutase PF13714.1 EON95986.1 - 1.1e-73 247.3 1.2 1.4e-73 247.0 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EON95986.1 - 1.4e-06 26.8 0.7 1.3e-05 23.6 0.1 2.3 1 1 1 3 3 3 1 Isocitrate lyase family Pantoate_transf PF02548.10 EON95986.1 - 0.059 12.4 0.5 2.6 7.1 0.1 2.6 1 1 1 2 2 2 0 Ketopantoate hydroxymethyltransferase Aldo_ket_red PF00248.16 EON95987.1 - 1.1e-72 244.2 0.0 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Meth_synt_2 PF01717.13 EON95988.1 - 1.8e-14 53.4 0.0 3.8e-10 39.2 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EON95988.1 - 0.00011 21.6 0.0 0.0065 15.7 0.0 2.9 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain zf-Mss51 PF13824.1 EON95988.1 - 0.053 13.3 0.0 2.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_11 PF13414.1 EON95989.1 - 2.6e-57 190.3 31.2 6e-18 64.2 0.7 6.5 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EON95989.1 - 2.8e-41 137.4 32.6 2.5e-06 26.8 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EON95989.1 - 2.3e-34 114.5 33.1 1.4e-05 24.6 0.1 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EON95989.1 - 9e-18 64.4 22.1 5.7e-05 23.6 0.0 7.0 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EON95989.1 - 4.2e-16 57.4 20.6 0.0012 18.4 0.2 7.8 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EON95989.1 - 6.2e-16 57.4 18.3 0.044 14.4 0.0 9.4 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EON95989.1 - 7e-16 57.9 17.3 1.5e-09 37.6 0.5 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EON95989.1 - 2.5e-15 55.3 10.3 0.018 15.1 0.1 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EON95989.1 - 9.7e-14 50.0 8.3 0.00089 18.8 0.0 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EON95989.1 - 2.3e-12 47.0 10.3 0.0041 17.4 0.0 6.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EON95989.1 - 8e-10 38.4 2.2 0.00085 19.1 0.1 4.9 5 1 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EON95989.1 - 1.5e-05 25.0 13.6 0.01 15.9 1.7 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EON95989.1 - 9.7e-05 22.1 0.3 0.27 11.2 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON95989.1 - 0.00013 22.1 21.1 0.19 12.2 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat PPR PF01535.15 EON95989.1 - 0.69 10.0 3.1 17 5.6 0.0 4.3 5 0 0 5 5 4 0 PPR repeat Sel1 PF08238.7 EON95989.1 - 1.7 9.3 7.3 68 4.3 0.1 4.3 4 0 0 4 4 3 0 Sel1 repeat MIT PF04212.13 EON95989.1 - 6.3 6.7 26.4 1.5 8.7 0.2 5.1 6 1 1 7 7 6 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.6 EON95989.1 - 6.6 6.2 8.1 3.2 7.3 0.6 3.3 2 1 1 3 3 3 0 XPC-binding domain Pectate_lyase PF03211.8 EON95990.1 - 4.1e-72 242.0 10.2 5e-72 241.8 7.1 1.0 1 0 0 1 1 1 1 Pectate lyase AA_permease PF00324.16 EON95991.1 - 1.1e-96 324.0 38.4 1.4e-96 323.7 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON95991.1 - 9.8e-33 113.3 42.3 1.3e-32 112.9 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EON95991.1 - 0.053 13.1 0.2 0.24 10.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) peroxidase PF00141.18 EON95992.1 - 2.9e-26 92.3 0.0 4.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF1830 PF08865.6 EON95992.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Hemerythrin PF01814.18 EON95993.1 - 9.7e-11 41.9 1.1 1.3e-10 41.5 0.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Methyltransf_23 PF13489.1 EON95994.1 - 3.2e-15 56.2 0.0 5.9e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Lactamase_B PF00753.22 EON95994.1 - 2.3e-10 40.4 0.5 1.7e-07 31.1 0.3 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EON95994.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_31 PF13847.1 EON95994.1 - 0.0011 18.5 0.0 1.6 8.3 0.0 3.0 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EON95994.1 - 0.0017 18.8 0.3 2.4 8.7 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EON95995.1 - 4.4e-46 156.2 0.0 1.3e-45 154.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON95995.1 - 1.3e-07 31.1 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF770 PF05591.7 EON95995.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF770) NAD_binding_2 PF03446.10 EON95995.1 - 0.042 13.6 0.1 0.092 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EON95995.1 - 0.076 12.3 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ras PF00071.17 EON95996.1 - 4.1e-43 146.5 0.0 6.4e-43 145.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EON95996.1 - 2.6e-15 56.9 0.0 3.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON95996.1 - 6.6e-12 45.0 0.0 1.9e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EON95996.1 - 4e-05 22.8 0.0 5.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EON95996.1 - 0.0036 17.2 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EON95996.1 - 0.0053 16.2 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EON95996.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON95996.1 - 0.026 14.6 0.0 0.048 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EON95996.1 - 0.029 13.8 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EON95996.1 - 0.032 13.4 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EON95996.1 - 0.049 13.3 0.1 0.25 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EON95996.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EON95996.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EON95996.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PIG-P PF08510.7 EON95997.1 - 1.9e-44 150.2 0.2 2.8e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 EON95997.1 - 3.2 8.1 10.1 5.3 7.4 7.0 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Glyco_hydro_3 PF00933.16 EON95998.1 - 2.6e-44 151.3 0.0 3.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON95998.1 - 2.9e-40 138.1 0.0 4.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON95998.1 - 4.5e-19 68.1 0.1 8e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain NAD_binding_10 PF13460.1 EON95998.1 - 0.063 13.2 0.1 8.3 6.3 0.0 2.4 1 1 0 2 2 2 0 NADH(P)-binding AXE1 PF05448.7 EON95999.1 - 0.075 11.5 0.0 0.29 9.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Aldo_ket_red PF00248.16 EON96000.1 - 5.3e-63 212.4 0.0 6.6e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mitofilin PF09731.4 EON96002.1 - 1.9e-152 508.9 3.9 3.2e-152 508.2 2.7 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Mur_ligase_M PF08245.7 EON96002.1 - 0.021 14.8 0.3 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 Mur ligase middle domain Mur_ligase_C PF02875.16 EON96002.1 - 0.04 13.9 0.4 0.4 10.7 0.0 2.9 4 0 0 4 4 4 0 Mur ligase family, glutamate ligase domain YlqD PF11068.3 EON96002.1 - 1.2 9.1 10.3 0.47 10.5 3.8 2.3 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 EON96002.1 - 2.7 5.7 6.0 4.1 5.1 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 EON96003.1 - 1.2e-44 152.5 56.3 2.8e-43 147.9 39.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON96003.1 - 6.6e-19 67.5 19.9 9e-19 67.0 13.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EON96003.1 - 1.4e-15 56.8 39.5 2.5e-15 56.0 7.3 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.3 EON96004.1 - 1.3e-53 182.0 0.9 2.4e-53 181.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON96004.1 - 5.4e-07 29.4 4.6 9.5e-07 28.6 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VSP PF03302.8 EON96005.1 - 0.00031 19.5 0.3 0.00035 19.3 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 EON96005.1 - 0.0023 17.4 0.1 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.1 EON96005.1 - 0.004 15.7 0.0 0.0053 15.2 0.0 1.1 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.5 EON96005.1 - 0.0083 15.4 0.8 0.016 14.5 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EON96005.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.2 EON96005.1 - 0.025 13.8 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1191 PF06697.7 EON96005.1 - 0.029 13.1 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) HemX PF04375.9 EON96005.1 - 0.035 12.7 0.1 0.048 12.2 0.1 1.1 1 0 0 1 1 1 0 HemX Mid2 PF04478.7 EON96005.1 - 0.038 13.4 0.2 0.079 12.3 0.0 1.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EON96005.1 - 0.057 11.6 0.0 0.067 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Nitrate_red_gam PF02665.9 EON96005.1 - 0.093 12.0 0.5 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit MGC-24 PF05283.6 EON96005.1 - 0.59 9.9 5.4 0.9 9.2 3.7 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Cerato-platanin PF07249.7 EON96006.1 - 1.5e-06 28.2 0.7 3e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Cerato-platanin DUF605 PF04652.11 EON96006.1 - 0.41 9.9 10.0 0.49 9.7 6.9 1.1 1 0 0 1 1 1 0 Vta1 like RGS PF00615.14 EON96007.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Aa_trans PF01490.13 EON96008.1 - 2.8e-79 266.5 27.2 3.3e-79 266.2 18.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.19 EON96009.1 - 1.1e-30 106.6 17.2 1.2e-30 106.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PrgI PF12666.2 EON96009.1 - 0.44 10.7 7.2 0.6 10.3 1.0 2.4 2 1 0 2 2 2 0 PrgI family protein SPC12 PF06645.8 EON96009.1 - 0.58 9.9 8.7 0.063 13.0 0.8 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TPR_12 PF13424.1 EON96010.1 - 1.2e-14 53.9 11.3 2.2e-08 33.9 0.4 4.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EON96010.1 - 3.3e-05 23.4 12.3 0.0007 19.3 0.2 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EON96010.1 - 0.00023 21.4 3.9 0.011 16.0 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 EON96010.1 - 0.00043 20.3 0.3 0.0037 17.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_8 PF13181.1 EON96010.1 - 0.0023 17.6 5.3 0.19 11.5 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_31 PF13614.1 EON96010.1 - 0.0041 17.0 0.1 0.12 12.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain TPR_11 PF13414.1 EON96010.1 - 0.0044 16.6 14.9 0.0064 16.1 2.8 4.3 4 1 2 6 6 6 3 TPR repeat TPR_7 PF13176.1 EON96010.1 - 0.0045 16.6 0.5 26 4.9 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EON96010.1 - 0.0077 16.3 1.5 4.7 7.3 0.1 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EON96010.1 - 0.016 15.7 0.0 21 6.0 0.0 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EON96010.1 - 0.022 14.6 7.0 2.8 7.9 0.6 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EON96010.1 - 0.028 15.1 2.4 10 6.9 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc5 PF12862.2 EON96010.1 - 0.047 13.5 1.3 2.6 7.9 0.2 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 EON96010.1 - 0.16 12.4 0.7 1e+02 3.6 0.0 4.3 6 0 0 6 6 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EON96010.1 - 0.2 11.9 5.2 23 5.4 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EON96010.1 - 0.37 10.9 7.3 0.16 12.1 0.5 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EON96010.1 - 2.1 8.0 12.4 1.2 8.9 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EON96011.1 - 6.3e-17 61.3 0.7 9.9e-17 60.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON96011.1 - 2.6e-06 27.2 0.0 5.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Bac_rhamnosid PF05592.6 EON96012.1 - 2.7e-111 372.2 0.2 3.4e-111 371.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EON96012.1 - 5.1e-39 133.5 5.6 1.3e-19 70.3 0.5 3.1 3 0 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain RNA_bind PF08675.6 EON96013.1 - 0.15 12.0 0.1 0.77 9.7 0.0 2.1 1 1 1 2 2 2 0 RNA binding domain Tape_meas_lam_C PF09718.5 EON96013.1 - 0.58 10.1 10.9 1.4 8.8 3.0 3.1 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ArsB PF02040.10 EON96014.1 - 5.4e-14 51.9 15.4 2.7e-10 39.8 5.9 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein Epimerase PF01370.16 EON96015.1 - 1.7e-08 34.1 0.0 0.00016 21.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EON96015.1 - 9.8e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EON96015.1 - 2.4e-05 24.6 0.0 6.2e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EON96015.1 - 0.00029 20.8 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EON96015.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EON96015.1 - 0.0032 16.2 0.0 0.0066 15.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EON96015.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EON96015.1 - 0.046 12.6 0.0 0.099 11.5 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein RNA_pol_Rpc34 PF05158.7 EON96016.1 - 2.5e-105 352.2 0.0 3.2e-105 351.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EON96016.1 - 0.00016 22.0 0.0 0.0025 18.1 0.0 2.7 3 1 1 4 4 4 1 Replication protein A C terminal HTH_34 PF13601.1 EON96016.1 - 0.012 15.6 0.7 0.033 14.2 0.0 2.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain Ribosomal_S25 PF03297.10 EON96016.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 S25 ribosomal protein ADH_N PF08240.7 EON96017.1 - 3.8e-32 110.2 0.1 3.8e-32 110.2 0.1 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON96017.1 - 4.1e-21 74.8 0.3 6.9e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON96017.1 - 3.2e-05 24.8 0.0 6.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EON96017.1 - 0.04 12.3 0.4 0.056 11.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EON96017.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EON96017.1 - 0.12 12.2 0.4 2.2 8.1 0.3 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldo_ket_red PF00248.16 EON96018.1 - 5.7e-52 176.2 0.0 6.4e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phosphoesterase PF04185.9 EON96019.1 - 8.4e-60 202.9 0.8 4.6e-59 200.4 0.6 2.2 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_2_N PF02837.13 EON96020.1 - 5.8e-13 48.7 0.0 2.2e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EON96020.1 - 2.4e-12 47.2 1.1 9.6e-12 45.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EON96020.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF3632 PF12311.3 EON96021.1 - 2e-37 128.8 3.4 6.5e-31 107.5 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3632) NmrA PF05368.8 EON96022.1 - 1.5e-23 83.2 0.1 2.3e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON96022.1 - 2.8e-12 47.0 0.3 4.2e-12 46.4 0.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON96022.1 - 0.0016 17.9 0.4 0.004 16.6 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON96022.1 - 0.0022 16.7 0.0 0.0043 15.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EON96022.1 - 0.092 12.6 0.1 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EON96022.1 - 0.1 11.5 0.8 0.15 11.0 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EON96022.1 - 0.11 11.3 0.7 0.97 8.2 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EON96023.1 - 2.4e-08 33.1 0.0 3.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syja_N PF02383.13 EON96024.1 - 1.7e-90 303.0 0.0 2.2e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 EON96025.1 - 0.00045 20.3 0.1 0.0079 16.2 0.1 2.6 1 1 0 1 1 1 1 Mur ligase middle domain His_Phos_2 PF00328.17 EON96026.1 - 6.2e-09 35.6 0.0 7.5e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Isochorismatase PF00857.15 EON96027.1 - 2.3e-24 86.2 0.4 2.7e-24 86.0 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family Pigment_DH PF06324.6 EON96027.1 - 0.024 13.8 0.6 0.044 13.0 0.4 1.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Actin PF00022.14 EON96028.1 - 1.3e-141 471.5 0.0 1.5e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EON96028.1 - 0.0002 20.0 0.0 0.097 11.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein MutL PF13941.1 EON96028.1 - 0.13 10.6 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 MutL protein DUF1583 PF07622.6 EON96029.1 - 0.15 10.5 0.1 0.23 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) Tannase PF07519.6 EON96030.1 - 1.3e-114 383.5 0.8 1.5e-114 383.3 0.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EON96030.1 - 0.0024 17.6 0.0 1.7 8.4 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96030.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Aldo_ket_red PF00248.16 EON96031.1 - 1e-62 211.5 0.0 1.2e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_15 PF09445.5 EON96031.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AA_permease_2 PF13520.1 EON96032.1 - 1.3e-38 132.6 42.4 1.9e-38 132.1 29.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON96032.1 - 1.8e-24 85.9 36.7 2.5e-24 85.4 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 EON96032.1 - 0.25 11.0 0.4 0.49 10.0 0.3 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Ras PF00071.17 EON96033.1 - 2.2e-58 196.2 0.1 2.5e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON96033.1 - 2e-19 70.2 0.1 3.3e-19 69.5 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EON96033.1 - 6.8e-15 54.7 0.0 8e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EON96033.1 - 7.6e-08 31.7 0.0 8.8e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EON96033.1 - 2.3e-07 30.4 0.0 3.2e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EON96033.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EON96033.1 - 0.045 13.8 0.1 1.9 8.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EON96033.1 - 0.048 12.8 0.2 0.18 11.0 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 Amidase02_C PF12123.3 EON96033.1 - 0.1 12.2 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_16 PF13191.1 EON96033.1 - 0.13 12.2 0.3 0.34 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EON96033.1 - 0.15 10.7 0.3 9.6 4.7 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Abhydrolase_3 PF07859.8 EON96034.1 - 2.3e-63 213.5 0.0 3e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON96034.1 - 2.6e-06 26.8 0.0 7.7e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EON96034.1 - 3.1e-06 26.2 0.5 1.9e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 EON96034.1 - 3.6e-06 25.8 0.0 7e-06 24.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EON96034.1 - 0.0015 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EON96034.1 - 0.0044 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PhzC-PhzF PF02567.11 EON96034.1 - 0.027 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Abhydrolase_6 PF12697.2 EON96034.1 - 0.12 12.2 0.2 0.3 10.9 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short_C2 PF13561.1 EON96035.1 - 3.4e-32 112.1 0.8 4.3e-32 111.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON96035.1 - 3.3e-28 98.6 4.0 4.3e-28 98.3 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96035.1 - 2e-12 47.1 1.9 2.9e-12 46.6 1.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON96035.1 - 9.2e-08 31.7 0.3 2.7e-07 30.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family End_tail_spike PF12219.3 EON96035.1 - 0.0036 17.1 0.1 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 Catalytic domain of bacteriophage endosialidase Polysacc_synt_2 PF02719.10 EON96035.1 - 0.0065 15.3 2.4 0.0087 14.9 1.7 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EON96035.1 - 0.027 14.2 1.1 0.027 14.2 0.8 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EON96035.1 - 0.24 11.3 5.3 1.3 8.9 3.7 2.4 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EON96035.1 - 0.63 9.0 4.6 0.23 10.5 0.9 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SET PF00856.23 EON96036.1 - 2.3e-18 67.0 0.0 1.9e-17 64.0 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EON96036.1 - 1.5e-11 43.7 10.0 7.8e-07 28.6 0.1 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EON96036.1 - 2.2e-06 27.1 13.3 0.0021 17.8 3.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EON96036.1 - 0.017 14.7 12.9 0.64 9.7 2.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EON96036.1 - 0.033 14.1 7.8 0.67 9.9 3.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SAF PF08666.7 EON96036.1 - 0.041 14.2 0.0 7.9 6.9 0.0 2.5 2 0 0 2 2 2 0 SAF domain TPR_8 PF13181.1 EON96036.1 - 1.2 9.0 7.0 7 6.6 1.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EON96036.1 - 3.7 8.4 9.3 4.1 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EON96036.1 - 5.1 7.8 15.2 3.2 8.5 0.5 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF500 PF04366.7 EON96037.1 - 7.8e-46 154.6 0.0 1.4e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Band_7 PF01145.20 EON96039.1 - 4e-11 43.1 1.0 4e-11 43.1 0.7 3.4 2 2 0 2 2 2 1 SPFH domain / Band 7 family Pox_Rap94 PF03294.9 EON96039.1 - 1.6 6.5 4.7 2.3 6.0 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 ABC_tran PF00005.22 EON96040.1 - 5e-08 33.3 0.2 4.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Fib_alpha PF08702.5 EON96040.1 - 0.041 14.0 1.2 0.17 12.0 0.9 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4440 PF14534.1 EON96041.1 - 1.9e-05 24.7 0.0 2.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) JmjC PF02373.17 EON96042.1 - 7.7e-37 126.0 0.4 2e-36 124.6 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EON96042.1 - 2.8e-21 75.5 5.1 6.5e-21 74.3 3.6 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EON96042.1 - 7.1e-21 74.1 5.7 7.1e-21 74.1 4.0 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EON96042.1 - 1.3e-15 56.6 0.3 2.4e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.5 EON96042.1 - 0.31 11.2 22.2 0.033 14.4 0.8 3.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Fringe PF02434.11 EON96043.1 - 9.4e-06 25.0 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EON96043.1 - 3.3e-05 23.2 0.0 0.00054 19.2 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Peptidase_M1 PF01433.15 EON96044.1 - 8.5e-132 439.9 0.8 1.1e-131 439.5 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EON96044.1 - 5.1e-72 242.8 0.0 1.9e-71 240.9 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EON96044.1 - 7.2e-20 71.3 1.7 5.3e-19 68.5 0.1 2.6 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EON96044.1 - 0.037 13.7 0.4 0.25 11.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF45 DUF1025 PF06262.6 EON96044.1 - 0.077 12.7 0.1 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Possibl zinc metallo-peptidase Ank_2 PF12796.2 EON96045.1 - 9e-34 115.6 8.0 6.3e-11 42.4 0.1 4.2 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EON96045.1 - 4.3e-32 109.4 9.5 3.5e-07 30.2 0.2 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EON96045.1 - 1e-27 94.5 10.6 2.2e-05 24.0 0.0 7.0 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EON96045.1 - 5.1e-26 90.5 9.8 9.1e-08 32.4 0.1 6.3 3 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON96045.1 - 4.7e-23 78.9 7.4 0.0017 18.4 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat ARGLU PF15346.1 EON96046.1 - 0.012 15.3 7.3 0.032 14.0 5.1 1.7 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF1690 PF07956.6 EON96046.1 - 0.024 14.5 13.9 0.046 13.7 9.6 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4404 PF14357.1 EON96046.1 - 0.52 10.7 13.4 0.095 13.1 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Med2 PF11214.3 EON96046.1 - 0.66 10.0 9.4 1.1 9.3 6.1 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 V_ATPase_I PF01496.14 EON96046.1 - 0.98 7.1 6.2 1.2 6.9 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3573 PF12097.3 EON96046.1 - 1.9 7.0 9.5 2 6.9 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) GRP PF07172.6 EON96046.1 - 2.4 8.7 19.6 0.65 10.5 10.4 2.4 2 0 0 2 2 2 0 Glycine rich protein family TMF_TATA_bd PF12325.3 EON96046.1 - 3.9 7.2 14.4 0.14 11.9 2.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding API5 PF05918.6 EON96046.1 - 6.8 5.0 14.2 2.4 6.5 5.6 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S8 PF00082.17 EON96047.1 - 3.3e-27 95.3 1.0 4.4e-26 91.6 0.7 2.1 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EON96047.1 - 9.5e-06 25.9 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) An_peroxidase PF03098.10 EON96048.1 - 4.3e-105 352.0 0.0 4.8e-103 345.3 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase Tcp11 PF05794.8 EON96049.1 - 1.3e-44 152.7 0.3 3.3e-44 151.3 0.0 1.8 2 0 0 2 2 2 1 T-complex protein 11 DUF607 PF04678.8 EON96049.1 - 7.7 6.3 7.9 27 4.6 5.5 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 3Beta_HSD PF01073.14 EON96050.1 - 2.6e-10 39.4 0.0 4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EON96050.1 - 5.5e-10 39.0 0.0 1.6e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON96050.1 - 1e-09 38.6 0.1 2.5e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EON96050.1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_61 PF03443.9 EON96051.1 - 5.1e-77 258.5 0.3 5.1e-77 258.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 FAD_binding_4 PF01565.18 EON96052.1 - 5.5e-22 77.7 1.0 2.2e-21 75.7 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EON96052.1 - 0.0011 18.8 0.7 0.0079 16.0 0.1 2.8 3 0 0 3 3 3 1 Berberine and berberine like DUF1643 PF07799.7 EON96052.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) GMC_oxred_C PF05199.8 EON96053.1 - 5.1e-32 111.1 0.0 6.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Phosphoesterase PF04185.9 EON96054.1 - 5.5e-26 91.6 0.3 1.3e-25 90.4 0.2 1.6 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_31 PF01055.21 EON96055.1 - 1.1e-67 228.7 4.1 5.9e-67 226.4 2.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 PhyH PF05721.8 EON96056.1 - 8.8e-12 45.5 0.0 1.6e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 EON96057.1 - 2.1e-12 46.5 2.8 2.3e-12 46.3 1.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON96057.1 - 6.3e-08 32.3 7.5 1.7e-07 31.0 5.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EON96058.1 - 2.5e-37 128.5 0.0 2.7e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EON96059.1 - 1.2e-59 202.0 21.6 8.8e-57 192.6 15.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96059.1 - 6.6e-11 41.5 8.0 6.6e-11 41.5 5.5 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EON96059.1 - 2.7e-05 22.5 10.1 0.00037 18.8 0.1 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPR_12 PF13424.1 EON96060.1 - 0.0015 18.4 0.9 0.027 14.4 0.1 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 EON96060.1 - 0.0049 16.7 0.1 1.6 8.8 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_10 PF13374.1 EON96060.1 - 0.057 13.3 0.1 20 5.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.1 EON96060.1 - 0.12 12.7 0.1 11 6.5 0.0 3.5 4 1 0 4 4 4 0 Pentatricopeptide repeat domain AdoMet_MTase PF07757.8 EON96060.1 - 0.14 12.3 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase TPR_19 PF14559.1 EON96060.1 - 0.15 12.4 1.2 1.6 9.1 0.4 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 EON96061.1 - 1.9e-25 88.6 6.9 2.5e-25 88.2 4.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Ecm29 PF13001.2 EON96061.1 - 0.013 14.0 0.2 0.014 13.9 0.1 1.0 1 0 0 1 1 1 0 Proteasome stabiliser DUF2019 PF09450.5 EON96061.1 - 0.085 12.7 1.2 0.93 9.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2019) DUF1319 PF07028.6 EON96061.1 - 0.11 12.6 8.7 0.11 12.6 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) PP_kinase_N PF13089.1 EON96061.1 - 0.12 12.4 1.4 0.27 11.3 0.0 1.9 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain Prefoldin PF02996.12 EON96061.1 - 0.12 11.9 5.2 0.09 12.4 0.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit AAA_23 PF13476.1 EON96061.1 - 0.14 12.4 5.6 0.2 11.9 3.9 1.3 1 0 0 1 1 1 0 AAA domain FTA4 PF13093.1 EON96061.1 - 0.17 11.2 4.1 0.25 10.7 2.8 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3496 PF12001.3 EON96061.1 - 0.21 11.8 3.9 0.26 11.5 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) MtrG PF04210.8 EON96061.1 - 0.33 10.6 0.1 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G XhlA PF10779.4 EON96061.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.4 2 1 0 2 2 2 0 Haemolysin XhlA Syntaxin PF00804.20 EON96061.1 - 1.2 9.3 7.2 14 5.8 0.1 2.2 2 0 0 2 2 2 0 Syntaxin Nsp1_C PF05064.8 EON96061.1 - 1.2 8.7 5.8 12 5.5 0.1 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region DivIC PF04977.10 EON96061.1 - 1.5 8.3 10.5 1.4 8.4 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EON96061.1 - 2 8.4 9.1 0.19 11.7 0.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EON96061.1 - 2.6 8.0 11.2 1.1 9.3 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.13 EON96061.1 - 7.4 6.6 10.6 1 9.3 0.5 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family BRO1 PF03097.13 EON96062.1 - 8.2e-115 383.5 0.0 1.4e-114 382.7 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EON96062.1 - 7.1e-83 277.9 0.0 1.8e-82 276.6 0.0 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MFS_1 PF07690.11 EON96063.1 - 3.4e-16 58.9 22.7 3.4e-16 58.9 15.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96063.1 - 3e-06 26.1 2.6 3e-06 26.1 1.8 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.1 EON96063.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) MFS_1 PF07690.11 EON96064.1 - 2.7e-37 128.2 25.4 2.7e-37 128.2 17.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.14 EON96065.1 - 9.1e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF1162 PF06650.7 EON96066.1 - 5e-96 321.1 0.0 3.1e-92 308.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EON96066.1 - 1.9e-42 143.5 0.1 7.1e-42 141.6 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EON96066.1 - 6.8e-07 29.3 0.1 2.6e-05 24.2 0.0 2.8 2 0 0 2 2 2 1 ATG C terminal domain OPT PF03169.10 EON96067.1 - 4.1e-132 441.7 44.2 5.7e-109 365.3 23.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Gal_mutarotas_2 PF13802.1 EON96067.1 - 0.045 13.6 0.3 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 Galactose mutarotase-like adh_short PF00106.20 EON96068.1 - 3.1e-30 105.2 0.4 4.2e-30 104.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96068.1 - 8.7e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96068.1 - 1.6e-12 47.5 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON96068.1 - 1.8e-09 37.8 0.1 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EON96068.1 - 4.3e-06 25.8 0.1 6.2e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EON96068.1 - 2.2e-05 24.0 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EON96068.1 - 0.003 16.8 0.1 0.0045 16.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 EON96068.1 - 0.011 15.2 0.1 0.035 13.6 0.1 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 EON96068.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 EON96068.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EON96068.1 - 0.11 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3429 PF11911.3 EON96069.1 - 2.7e-38 131.1 10.2 3.4e-38 130.8 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Iron_permease PF04120.7 EON96069.1 - 0.063 12.8 0.6 0.14 11.7 0.4 1.6 1 0 0 1 1 1 0 Low affinity iron permease WD40 PF00400.27 EON96070.1 - 1.8e-35 119.5 7.1 1.4e-05 24.8 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EON96070.1 - 5.8e-14 51.5 1.0 5.8e-14 51.5 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EON96070.1 - 7.2e-07 28.7 1.1 1.5e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EON96070.1 - 0.0007 17.8 0.1 0.036 12.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 EON96070.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Acetyltransf_10 PF13673.1 EON96071.1 - 2.9e-07 30.6 0.0 9.4e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON96071.1 - 1.7e-05 24.7 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON96071.1 - 0.0062 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EON96071.1 - 0.048 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_9 PF13527.1 EON96071.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON96071.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Mannosyl_trans3 PF11051.3 EON96072.1 - 2.3e-38 132.1 0.1 1.3e-37 129.6 0.1 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative Asp_Glu_race PF01177.17 EON96073.1 - 1e-27 97.4 0.9 1.2e-27 97.2 0.6 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.10 EON96073.1 - 0.016 14.3 0.5 0.069 12.2 0.1 2.1 2 1 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Actin PF00022.14 EON96074.1 - 6.2e-76 255.3 0.0 7e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Actin Peptidase_S10 PF00450.17 EON96075.1 - 1.6e-72 245.0 0.0 3.7e-72 243.7 0.0 1.5 1 1 1 2 2 2 1 Serine carboxypeptidase Synuclein PF01387.12 EON96076.1 - 0.064 13.1 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Synuclein TauD PF02668.11 EON96077.1 - 2.1e-12 47.2 0.0 3.1e-12 46.7 0.0 1.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF996 PF06195.8 EON96078.1 - 0.062 13.3 4.9 0.1 12.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF962 PF06127.6 EON96078.1 - 0.14 12.0 2.5 3.6 7.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) TRP PF06011.7 EON96078.1 - 7.1 5.0 9.3 1.4 7.4 3.4 1.8 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel FAD_binding_4 PF01565.18 EON96079.1 - 1.2e-24 86.3 0.4 2.2e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain RNF111_N PF15303.1 EON96080.1 - 0.0085 15.6 0.3 0.013 15.0 0.2 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus TauD PF02668.11 EON96081.1 - 8e-12 45.3 0.1 9.6e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EON96081.1 - 0.00031 19.7 0.1 0.00043 19.2 0.0 1.1 1 0 0 1 1 1 1 CsiD DUF4091 PF13320.1 EON96082.1 - 0.062 13.2 0.2 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Snf7 PF03357.16 EON96083.1 - 3e-44 150.4 9.4 3.4e-44 150.2 6.5 1.0 1 0 0 1 1 1 1 Snf7 MscS_porin PF12795.2 EON96083.1 - 0.00026 20.4 9.8 0.13 11.5 0.0 3.1 1 1 1 3 3 3 1 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 EON96083.1 - 0.0037 17.4 6.6 0.29 11.4 0.8 3.2 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EON96083.1 - 0.0062 15.7 3.6 0.029 13.5 0.4 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Sec34 PF04136.10 EON96083.1 - 0.0082 15.8 2.5 0.32 10.6 1.0 2.1 2 0 0 2 2 2 1 Sec34-like family CENP-F_leu_zip PF10473.4 EON96083.1 - 0.017 14.9 9.2 0.48 10.2 6.9 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Alpha-2-MRAP_C PF06401.6 EON96083.1 - 0.019 14.8 1.5 0.034 14.0 0.9 1.5 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain FlxA PF14282.1 EON96083.1 - 0.025 14.5 11.3 0.021 14.7 6.7 1.7 1 1 1 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.15 EON96083.1 - 0.029 14.1 9.5 0.5 10.1 0.0 3.9 2 1 0 2 2 1 0 Prefoldin subunit FliD_C PF07195.7 EON96083.1 - 0.042 13.1 7.1 0.25 10.5 0.0 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2312 PF10073.4 EON96083.1 - 0.086 12.2 2.4 0.23 10.8 0.2 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) NuA4 PF09340.5 EON96083.1 - 0.098 12.3 1.6 0.18 11.4 1.1 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 AAA_13 PF13166.1 EON96083.1 - 0.12 10.7 6.2 0.24 9.8 4.3 1.5 1 1 0 1 1 1 0 AAA domain DUF3508 PF12018.3 EON96083.1 - 0.15 11.0 3.9 0.21 10.5 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) EMP24_GP25L PF01105.19 EON96083.1 - 0.16 11.7 5.4 3.4 7.3 2.1 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 EON96083.1 - 0.16 11.5 5.4 0.33 10.5 0.5 2.4 1 1 1 2 2 2 0 IncA protein Peptidase_M13 PF01431.16 EON96083.1 - 0.2 10.7 2.6 0.28 10.3 1.8 1.1 1 0 0 1 1 1 0 Peptidase family M13 DUF2205 PF10224.4 EON96083.1 - 0.22 11.1 4.0 1.5 8.4 0.6 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) COG2 PF06148.6 EON96083.1 - 0.38 10.6 7.5 0.86 9.4 2.6 2.7 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EON96083.1 - 0.39 10.7 10.7 0.12 12.4 4.2 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF342 PF03961.8 EON96083.1 - 0.47 8.7 7.7 1.6 7.0 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) IFT46_B_C PF12317.3 EON96083.1 - 0.59 9.4 5.0 0.89 8.8 3.3 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal OmpH PF03938.9 EON96083.1 - 0.7 9.8 13.2 0.58 10.0 6.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EON96083.1 - 0.85 8.4 7.4 1.5 7.6 5.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 EON96083.1 - 0.9 9.4 9.9 0.44 10.4 4.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4337 PF14235.1 EON96083.1 - 1.6 8.5 6.6 0.38 10.5 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 EON96083.1 - 2.1 8.7 7.9 7.9 6.8 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tup_N PF08581.5 EON96083.1 - 3.1 8.0 9.8 9.4 6.5 6.3 2.2 1 1 1 2 2 2 0 Tup N-terminal FlaC_arch PF05377.6 EON96083.1 - 3.4 7.6 5.9 10 6.1 0.1 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EON96083.1 - 4.6 6.1 9.9 3.1 6.7 5.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Aldo_ket_red PF00248.16 EON96085.1 - 9.6e-67 224.7 0.0 1.2e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.15 EON96087.1 - 2.3e-26 93.2 0.2 3.3e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EON96087.1 - 1e-08 35.5 3.4 7.8e-05 22.8 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EON96087.1 - 1e-06 28.4 0.2 0.00013 21.7 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EON96087.1 - 2.9e-06 26.7 3.4 6.1e-06 25.7 0.4 2.5 2 1 0 2 2 2 1 Amidohydrolase family CrtC PF07143.6 EON96088.1 - 0.00018 20.9 3.7 0.0015 17.9 2.6 2.1 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Asparaginase_2 PF01112.13 EON96089.1 - 2.7e-82 276.0 5.7 8.1e-82 274.4 3.9 1.6 1 1 0 1 1 1 1 Asparaginase MatE PF01554.13 EON96090.1 - 2e-33 115.2 24.3 4.5e-22 78.3 8.4 2.8 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EON96090.1 - 0.0085 15.8 6.5 0.0085 15.8 4.5 3.1 1 1 2 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF2414 PF10309.4 EON96091.1 - 6.8e-16 57.6 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) ABC_membrane PF00664.18 EON96092.1 - 4.8e-47 160.6 11.9 6.4e-47 160.2 8.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EON96092.1 - 2.8e-33 115.0 0.0 8.4e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EON96092.1 - 1.7e-05 24.1 0.2 0.00062 19.0 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EON96092.1 - 8.2e-05 22.6 0.1 0.00025 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EON96092.1 - 0.00019 21.5 0.5 0.91 9.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EON96092.1 - 0.00087 20.0 0.1 0.0029 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EON96092.1 - 0.0025 17.3 0.1 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EON96092.1 - 0.0033 17.5 0.1 0.02 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EON96092.1 - 0.0088 16.2 0.1 0.11 12.6 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EON96092.1 - 0.0099 15.3 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 EON96092.1 - 0.022 14.4 0.1 0.086 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EON96092.1 - 0.025 13.9 0.7 0.22 10.9 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EON96092.1 - 0.033 13.6 0.3 0.28 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EON96092.1 - 0.036 13.9 1.1 0.31 10.9 0.8 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EON96092.1 - 0.037 12.6 0.5 0.086 11.4 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EON96092.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ribosomal_S3Ae PF01015.13 EON96093.1 - 1.1e-81 272.8 3.5 1.4e-81 272.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 EON96093.1 - 0.03 14.4 0.4 0.16 12.1 0.0 2.2 2 1 0 2 2 2 0 Syntaxin DNA_pol_B_palm PF14792.1 EON96094.1 - 3.1e-21 75.5 0.1 9.7e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EON96094.1 - 8.9e-21 73.1 0.8 2.1e-20 71.9 0.6 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EON96094.1 - 1.2e-18 66.5 0.0 2.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EON96094.1 - 3.4e-11 43.1 0.1 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EON96094.1 - 0.025 14.8 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DnaJ PF00226.26 EON96095.1 - 2.3e-22 78.4 0.7 6.9e-22 76.9 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain MIP-T3 PF10243.4 EON96095.1 - 4.8e-05 22.0 53.4 7.7e-05 21.3 37.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 eIF-3_zeta PF05091.7 EON96095.1 - 4 5.9 21.1 8 4.9 14.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Fibrillarin PF01269.12 EON96096.1 - 8.8e-107 355.2 0.0 1.1e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EON96096.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EON96096.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GFO_IDH_MocA PF01408.17 EON96097.1 - 2.2e-22 79.8 0.0 3.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EON96097.1 - 5.3e-06 26.2 0.0 8.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EON96097.1 - 0.00079 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 EON96097.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EON96098.1 - 7.7e-77 258.7 0.0 9.8e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON96098.1 - 9.9e-07 27.9 1.0 0.0033 16.3 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EON96098.1 - 0.0002 21.5 0.1 0.0011 19.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON96098.1 - 0.00056 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON96098.1 - 0.0019 18.0 0.1 0.014 15.2 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON96098.1 - 0.0034 15.9 0.0 0.35 9.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EON96098.1 - 0.026 13.3 0.2 0.57 8.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EON96098.1 - 0.039 12.8 0.1 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EON96098.1 - 0.075 13.4 0.4 0.28 11.5 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EON96098.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EON96098.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HNH_2 PF13391.1 EON96099.1 - 0.0018 18.0 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF1470 PF07336.6 EON96099.1 - 0.24 11.7 7.6 0.91 9.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) CLP_protease PF00574.18 EON96100.1 - 7.8e-51 172.3 0.1 9.6e-51 172.0 0.1 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_M22 PF00814.20 EON96101.1 - 3.6e-80 269.2 0.0 4.4e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family UPRTase PF14681.1 EON96102.1 - 4.8e-79 264.3 0.0 6.8e-79 263.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EON96102.1 - 0.00026 20.6 0.0 0.00061 19.5 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EON96102.1 - 0.15 11.8 0.2 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Glyco_hydro_3 PF00933.16 EON96103.1 - 1.6e-58 198.0 0.0 2.2e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON96103.1 - 2.4e-54 184.2 0.1 3.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON96103.1 - 1.5e-23 82.5 0.0 2.5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Vps39_2 PF10367.4 EON96104.1 - 4.9e-09 36.3 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EON96104.1 - 0.0083 16.1 0.0 0.074 13.0 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 NAP PF00956.13 EON96105.1 - 1.6e-88 295.9 11.8 1.6e-88 295.9 8.2 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.7 EON96105.1 - 2.2 6.0 34.3 0.38 8.6 16.1 2.1 2 0 0 2 2 2 0 Nop14-like family Sec23_trunk PF04811.10 EON96106.1 - 1.6e-80 270.0 0.0 2.2e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EON96106.1 - 1.8e-34 117.2 1.0 3.8e-34 116.2 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EON96106.1 - 3.2e-30 104.4 0.2 6.9e-30 103.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EON96106.1 - 3.2e-16 58.5 6.5 6.4e-16 57.6 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EON96106.1 - 1e-11 44.3 0.0 2.5e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Spt4 PF06093.8 EON96107.1 - 3.4e-32 110.1 0.0 4.2e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DNA_primase_lrg PF04104.9 EON96108.1 - 9.1e-80 267.6 0.0 1.3e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_23 PF13489.1 EON96109.1 - 3.9e-06 26.6 0.0 5.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96109.1 - 3.1e-05 23.5 0.0 0.056 13.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Kin17_mid PF10357.4 EON96110.1 - 1.7e-51 173.1 1.1 1.7e-51 173.1 0.7 2.3 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EON96110.1 - 3.1e-06 27.1 0.9 6.7e-06 26.0 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EON96110.1 - 0.00011 22.2 1.6 0.00031 20.8 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EON96110.1 - 0.0005 20.1 2.4 0.00082 19.4 0.2 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 EON96110.1 - 0.051 12.1 0.1 0.051 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF629) 2-Hacid_dh_C PF02826.14 EON96111.1 - 1.4e-52 177.3 0.0 2.2e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON96111.1 - 3.3e-35 120.4 0.0 4.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EON96111.1 - 0.00041 20.2 0.1 0.00078 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EON96111.1 - 0.0056 16.5 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EON96111.1 - 0.045 13.1 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EON96111.1 - 0.052 13.2 1.0 3 7.4 0.4 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.20 EON96111.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain AAA_18 PF13238.1 EON96112.1 - 6.7e-28 97.5 1.5 1.1e-27 96.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EON96112.1 - 1.6e-14 54.7 1.0 3.6e-14 53.6 0.7 1.7 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EON96112.1 - 7e-06 25.9 0.1 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA PF00004.24 EON96112.1 - 5e-05 23.5 0.0 0.0006 20.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EON96112.1 - 9.1e-05 22.3 0.2 0.00028 20.8 0.1 1.7 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EON96112.1 - 9.8e-05 22.2 0.2 0.003 17.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EON96112.1 - 0.00011 22.1 0.4 0.00068 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EON96112.1 - 0.0022 17.7 0.7 0.0049 16.5 0.1 1.9 2 0 0 2 2 2 1 NTPase Thymidylate_kin PF02223.12 EON96112.1 - 0.0045 16.3 0.1 2.7 7.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 EON96112.1 - 0.006 15.8 0.3 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EON96112.1 - 0.017 15.2 0.3 0.028 14.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EON96112.1 - 0.027 14.4 0.6 0.052 13.5 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EON96112.1 - 0.048 13.0 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EON96112.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.7 EON96112.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EON96112.1 - 0.085 12.7 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EON96112.1 - 0.086 12.4 0.2 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EON96112.1 - 0.087 12.5 0.6 0.16 11.7 0.4 1.4 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EON96112.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EON96112.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 EON96112.1 - 0.13 12.5 1.3 0.61 10.3 0.9 2.0 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EON96112.1 - 0.13 11.6 0.2 0.32 10.4 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family MAPEG PF01124.13 EON96113.1 - 7.2e-21 74.1 0.2 9.1e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 MAPEG family CTD_bind PF04818.8 EON96114.1 - 3.1e-16 59.3 0.1 6.7e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. EPL1 PF10513.4 EON96116.1 - 2.9e-30 105.6 3.2 2.9e-30 105.6 2.2 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like IF3_C PF00707.17 EON96116.1 - 1.3 8.8 4.8 2.6 7.8 0.2 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-3, C-terminal domain Beta-lactamase PF00144.19 EON96117.1 - 5.9e-09 35.3 0.2 1e-08 34.6 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase PMEI PF04043.10 EON96118.1 - 0.11 12.3 3.9 0.14 12.0 2.7 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FliT PF05400.8 EON96118.1 - 0.37 11.2 3.2 0.87 10.0 2.2 1.7 1 1 0 1 1 1 0 Flagellar protein FliT F-box PF00646.28 EON96119.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain Sugar_tr PF00083.19 EON96120.1 - 7e-40 136.9 1.0 8.2e-40 136.7 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96120.1 - 9.5e-18 64.0 1.7 1.2e-17 63.7 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 EON96120.1 - 0.0025 16.5 0.3 0.0036 16.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) EMP70 PF02990.11 EON96120.1 - 0.059 11.8 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Ribosomal_L11_N PF03946.9 EON96121.1 - 3.7e-18 64.7 0.1 6.2e-18 64.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EON96121.1 - 5.3e-11 42.4 0.2 9.8e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Met_asp_mut_E PF06368.6 EON96121.1 - 0.067 11.3 0.4 0.09 10.9 0.3 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) NIF PF03031.13 EON96122.1 - 3.6e-17 62.4 0.0 4.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Elf1 PF05129.8 EON96123.1 - 0.063 12.9 0.3 0.063 12.9 0.2 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ILVD_EDD PF00920.16 EON96124.1 - 7.4e-207 687.8 0.1 8.5e-207 687.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_L23eN PF03939.8 EON96126.1 - 7.8 6.6 8.8 25 5.0 5.5 2.1 2 1 1 3 3 3 0 Ribosomal protein L23, N-terminal domain Peptidase_C12 PF01088.16 EON96127.1 - 3.3e-71 238.8 0.0 4.8e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_47 PF01532.15 EON96128.1 - 5e-167 556.1 0.0 5.8e-167 555.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sugar_tr PF00083.19 EON96129.1 - 2.1e-05 23.2 0.7 2.3e-05 23.2 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PspC PF04024.7 EON96129.1 - 0.11 12.0 3.4 0.15 11.5 2.4 1.4 1 1 0 1 1 1 0 PspC domain Ribosomal_L39 PF00832.15 EON96129.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L39 protein MIP PF00230.15 EON96130.1 - 1e-33 116.6 11.9 1.2e-33 116.4 8.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4554 PF15091.1 EON96131.1 - 0.048 12.3 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Abhydrolase_6 PF12697.2 EON96132.1 - 8.6e-23 81.3 0.1 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96132.1 - 6.9e-17 61.7 0.0 1.4e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON96132.1 - 3.3e-06 26.9 0.0 6.6e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EON96132.1 - 0.00051 20.3 0.0 0.00069 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EON96132.1 - 0.00062 19.2 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EON96132.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.9 EON96132.1 - 0.015 13.8 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Lipase_3 PF01764.20 EON96132.1 - 0.036 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Clathrin_lg_ch PF01086.12 EON96133.1 - 1e-69 234.9 7.2 1.2e-69 234.7 5.0 1.0 1 0 0 1 1 1 1 Clathrin light chain RAM PF15320.1 EON96133.1 - 0.032 14.4 2.2 0.076 13.2 1.5 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein ATP-synt_B PF00430.13 EON96133.1 - 0.035 13.9 4.8 0.056 13.2 3.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SNARE PF05739.14 EON96134.1 - 5.7e-19 67.5 2.5 5.7e-19 67.5 1.8 2.9 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EON96134.1 - 7.5e-12 45.3 1.0 7.5e-12 45.3 0.7 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EON96134.1 - 0.051 13.1 9.5 0.12 11.8 0.5 2.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 EON96134.1 - 0.14 12.5 3.0 0.27 11.6 0.4 2.4 2 1 0 2 2 2 0 DNA repair REX1-B HAUS-augmin3 PF14932.1 EON96134.1 - 1.8 7.7 9.7 0.55 9.3 0.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FUSC PF04632.7 EON96134.1 - 2.9 6.1 4.9 0.55 8.5 0.7 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.11 EON96135.1 - 4.2e-18 65.1 10.5 5e-18 64.9 7.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0104 PF03706.8 EON96135.1 - 0.0012 18.1 2.4 0.0016 17.8 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) RRM_DME PF15628.1 EON96136.1 - 0.058 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 RRM in Demeter Caveolin PF01146.12 EON96136.1 - 7.5 6.1 7.1 14 5.2 5.0 1.4 1 0 0 1 1 1 0 Caveolin Xan_ur_permease PF00860.15 EON96137.1 - 1.1e-30 106.4 26.4 2.4e-16 59.2 6.3 3.2 3 0 0 3 3 3 3 Permease family CASP_C PF08172.7 EON96138.1 - 1.1e-89 299.7 0.2 1.1e-89 299.7 0.2 3.5 2 1 0 3 3 3 1 CASP C terminal bZIP_2 PF07716.10 EON96138.1 - 0.0066 16.2 4.0 0.0066 16.2 2.7 8.0 8 1 0 8 8 8 1 Basic region leucine zipper UPF0184 PF03670.8 EON96138.1 - 0.046 13.8 0.4 0.046 13.8 0.3 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) HNF_C PF09354.5 EON96138.1 - 0.11 13.6 1.2 0.45 11.6 0.8 2.1 1 0 0 1 1 1 0 HNF3 C-terminal domain ATG16 PF08614.6 EON96138.1 - 0.29 10.9 55.7 0.46 10.2 5.4 4.6 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Metal_resist PF13801.1 EON96138.1 - 0.39 10.7 0.0 0.39 10.7 0.0 4.2 4 1 0 4 4 4 0 Heavy-metal resistance Filament PF00038.16 EON96138.1 - 0.45 9.9 50.1 2 7.7 4.9 3.5 3 1 1 4 4 4 0 Intermediate filament protein ADIP PF11559.3 EON96138.1 - 3 7.7 70.8 0.093 12.6 5.1 7.1 4 1 3 7 7 7 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 EON96138.1 - 4.3 6.8 54.5 1.7 8.1 0.0 4.6 3 1 1 5 5 5 0 Ezrin/radixin/moesin family Ribosomal_L22 PF00237.14 EON96139.1 - 4.7e-34 116.4 0.1 6.9e-34 115.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HSP90 PF00183.13 EON96140.1 - 8e-256 849.5 33.0 9.4e-256 849.3 22.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EON96140.1 - 5.6e-12 45.3 0.1 1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EON96140.1 - 3.4e-11 42.9 0.5 3.4e-11 42.9 0.4 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 EON96140.1 - 0.066 13.5 0.6 0.066 13.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 EON96140.1 - 0.15 11.8 2.7 0.1 12.3 0.2 2.0 2 0 0 2 2 2 0 Tumour suppressor protein EF-hand_1 PF00036.27 EON96141.1 - 1.7e-36 120.7 14.3 1.3e-09 36.6 0.6 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EON96141.1 - 8.7e-35 118.1 7.5 8.4e-16 57.3 0.5 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EON96141.1 - 2.8e-33 113.8 5.4 8.1e-20 70.7 1.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EON96141.1 - 1.8e-24 83.3 12.7 8.7e-09 34.5 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EON96141.1 - 9.3e-23 78.5 8.4 5.1e-06 25.5 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EON96141.1 - 9.2e-13 47.9 0.6 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EON96141.1 - 2.3e-08 33.7 1.7 0.00073 19.2 0.1 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EON96141.1 - 4.8e-08 32.4 0.1 0.025 14.1 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 EON96141.1 - 2.6e-07 30.6 0.0 0.0049 16.8 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EON96141.1 - 4.9e-06 26.4 2.8 5.7e-06 26.2 0.2 2.3 3 0 0 3 3 3 1 Ca2+ insensitive EF hand TerB PF05099.8 EON96141.1 - 0.00015 21.4 0.8 0.26 11.0 0.1 2.5 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 EON96141.1 - 0.0033 17.4 0.7 1.6 8.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EON96141.1 - 0.0035 16.9 0.1 0.16 11.5 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Caleosin PF05042.8 EON96141.1 - 0.062 12.8 0.1 4.1 6.9 0.1 2.7 1 1 0 1 1 1 0 Caleosin related protein DUF3349 PF11829.3 EON96141.1 - 0.11 12.9 0.9 13 6.2 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EON96141.1 - 0.12 12.0 1.3 1 9.1 0.1 3.0 1 1 2 3 3 3 0 EF hand Toprim_2 PF13155.1 EON96141.1 - 0.22 11.8 1.8 9.9 6.5 0.2 2.5 1 1 1 2 2 2 0 Toprim-like PB1 PF00564.19 EON96141.1 - 0.56 9.9 2.5 37 4.0 0.0 3.2 2 1 1 3 3 3 0 PB1 domain Abhydrolase_6 PF12697.2 EON96142.1 - 9.9e-14 51.7 0.0 1.1e-13 51.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96142.1 - 1.5e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family EF1G PF00647.14 EON96143.1 - 5.3e-41 138.6 0.0 9.3e-41 137.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EON96143.1 - 7.2e-15 54.7 0.0 2.1e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EON96143.1 - 2.6e-11 43.2 0.1 9e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EON96143.1 - 7e-08 32.5 0.1 8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EON96143.1 - 2.9e-06 27.4 0.0 7.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EON96143.1 - 5.8e-06 26.7 0.0 1.5e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EON96143.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2276 PF10040.4 EON96143.1 - 0.13 12.5 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2276) Ank_2 PF12796.2 EON96144.1 - 1.9e-16 60.1 0.0 5.5e-08 33.0 0.0 4.0 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EON96144.1 - 2.6e-16 59.6 0.1 4.2e-07 30.2 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EON96144.1 - 2e-11 43.1 2.9 0.00038 20.1 0.0 4.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EON96144.1 - 2.7e-11 43.3 0.1 8.8e-06 25.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON96144.1 - 3.2e-09 36.1 0.1 0.086 13.1 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.7 EON96144.1 - 1.5e-05 24.6 0.0 3.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EON96144.1 - 0.00065 19.7 1.9 0.0097 15.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EON96144.1 - 0.0037 17.4 0.6 0.019 15.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF2730 PF10805.3 EON96144.1 - 0.047 13.4 5.6 0.54 10.0 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) AAA_10 PF12846.2 EON96144.1 - 0.071 12.5 0.4 0.5 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain Hom_end_hint PF05203.11 EON96144.1 - 0.12 12.1 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint AAA_18 PF13238.1 EON96144.1 - 0.12 12.7 1.1 4.4 7.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain SDH_alpha PF03313.10 EON96144.1 - 0.17 10.8 0.3 0.51 9.3 0.2 1.8 1 0 0 1 1 1 0 Serine dehydratase alpha chain VSG_B PF13206.1 EON96144.1 - 1.1 8.2 8.3 1.9 7.5 5.8 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Sec7 PF01369.15 EON96145.1 - 2.3e-26 92.6 0.5 3.8e-26 91.9 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EON96145.1 - 0.00013 22.1 0.0 0.00032 20.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EON96145.1 - 0.00097 19.2 0.1 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CENP-B_dimeris PF09026.5 EON96145.1 - 5.2 7.3 12.5 13 6.1 8.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myosin_head PF00063.16 EON96146.1 - 3.1e-242 805.5 0.3 3.1e-242 805.5 0.2 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EON96146.1 - 8.2e-35 118.8 3.4 2.9e-34 117.0 2.3 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EON96146.1 - 7.4e-15 53.1 36.8 0.00014 21.1 0.5 7.1 6 0 0 6 6 6 5 IQ calmodulin-binding motif Fez1 PF06818.10 EON96146.1 - 0.00076 19.5 20.9 0.015 15.3 7.4 2.6 1 1 1 2 2 2 2 Fez1 AAA_22 PF13401.1 EON96146.1 - 0.0012 19.0 0.0 0.0048 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 EON96146.1 - 0.0043 16.9 0.2 0.0043 16.9 0.1 3.2 4 0 0 4 4 3 1 Flagella accessory protein C (FlaC) GAS PF13851.1 EON96146.1 - 0.0084 15.3 22.0 0.095 11.8 15.2 2.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_16 PF13191.1 EON96146.1 - 0.0085 16.0 0.6 0.79 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain CENP-F_leu_zip PF10473.4 EON96146.1 - 0.013 15.3 21.6 0.25 11.2 2.5 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_19 PF13245.1 EON96146.1 - 0.021 14.5 0.0 0.084 12.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Myosin_N PF02736.14 EON96146.1 - 0.098 12.3 1.2 0.22 11.2 0.8 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 EON96146.1 - 0.13 11.3 4.7 0.34 10.0 1.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EON96146.1 - 1.3 8.8 12.0 1.5 8.6 5.9 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus M_domain PF12938.2 EON96146.1 - 4.6 6.9 10.1 7 6.3 2.9 2.6 2 0 0 2 2 2 0 M domain of GW182 APG6 PF04111.7 EON96146.1 - 5 6.0 25.3 3.4 6.6 11.0 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 AA_kinase PF00696.23 EON96147.1 - 4.2e-31 108.3 0.2 3.1e-30 105.4 0.1 2.3 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 EON96147.1 - 1.6e-16 59.3 0.3 3.7e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EON96147.1 - 6.9e-14 51.1 3.4 2.1e-10 39.9 0.2 2.6 2 0 0 2 2 2 2 ACT domain Kinesin PF00225.18 EON96148.1 - 2e-104 348.9 0.5 2e-104 348.9 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 EON96148.1 - 1.5e-05 23.7 37.4 1.5e-05 23.7 25.9 1.7 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EON96148.1 - 0.011 14.9 12.8 0.14 11.2 1.7 3.5 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DEAD PF00270.24 EON96148.1 - 0.04 13.3 1.7 3.3 7.1 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase Baculo_PEP_C PF04513.7 EON96148.1 - 3.8 7.3 8.9 15 5.3 1.2 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.1 EON96148.1 - 6.3 6.9 7.0 0.62 10.1 0.1 2.7 3 1 0 3 3 3 0 AAA domain GTP_CH_N PF12471.3 EON96149.1 - 4e-93 310.4 0.0 5.6e-93 309.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EON96149.1 - 2.3e-15 56.2 0.0 3.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II zf-C2H2 PF00096.21 EON96150.1 - 2.9e-05 24.1 20.3 0.5 10.8 0.8 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON96150.1 - 8.7e-05 22.5 16.5 0.12 12.7 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EON96150.1 - 0.0012 18.7 1.4 0.068 13.1 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger TT_ORF2 PF02957.10 EON96150.1 - 0.017 15.8 2.1 0.048 14.3 1.4 1.7 1 0 0 1 1 1 0 TT viral ORF2 DUF629 PF04780.7 EON96150.1 - 0.16 10.4 0.3 0.42 9.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Acyltransferase PF01553.16 EON96151.1 - 0.0026 17.2 0.0 0.0079 15.6 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase DUF3538 PF12057.3 EON96151.1 - 0.029 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Ham1p_like PF01725.11 EON96152.1 - 2.8e-51 173.6 0.0 3.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family p450 PF00067.17 EON96153.1 - 0.0025 16.4 0.0 0.023 13.2 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_16 PF10294.4 EON96154.1 - 1.5e-12 47.3 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EON96154.1 - 0.0035 17.8 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EON96154.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_C78 PF07910.8 EON96155.1 - 1.3e-66 223.9 0.0 2.4e-66 222.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family C78 Peptidase_C47 PF05543.8 EON96155.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Staphopain peptidase C47 zf-Di19 PF05605.7 EON96155.1 - 0.057 13.5 0.5 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MBOAT PF03062.14 EON96156.1 - 2.8e-35 121.9 19.3 4.7e-35 121.2 12.2 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family p53-inducible11 PF14936.1 EON96156.1 - 0.17 11.8 2.9 0.36 10.7 2.0 1.5 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Pkinase PF00069.20 EON96157.1 - 8.7e-47 159.4 0.0 2e-45 154.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96157.1 - 1.2e-25 90.1 0.0 4e-25 88.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EON96157.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EON96157.1 - 0.15 10.9 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like AMPKBI PF04739.10 EON96158.1 - 2.4e-29 101.1 2.1 3e-29 100.8 0.3 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Ras PF00071.17 EON96159.1 - 2.1e-29 102.0 0.5 8.4e-24 83.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EON96159.1 - 6.2e-05 23.4 0.1 0.00012 22.5 0.1 1.6 1 1 0 1 1 1 1 Miro-like protein HNOBA PF07701.9 EON96159.1 - 0.008 15.4 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding associated GTP_EFTU PF00009.22 EON96159.1 - 0.051 13.0 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EON96159.1 - 0.085 12.0 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family EF-hand_1 PF00036.27 EON96160.1 - 1.3e-26 89.8 12.7 4.5e-07 28.7 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EON96160.1 - 7.5e-24 83.6 3.1 1.1e-12 47.9 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EON96160.1 - 7.9e-20 68.9 7.4 4.3e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EON96160.1 - 2.9e-18 64.3 14.9 2e-06 26.8 0.2 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EON96160.1 - 2.9e-15 55.6 13.0 2.3e-05 23.9 0.9 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EON96160.1 - 4e-07 30.0 0.0 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EON96160.1 - 1.6e-06 27.7 6.8 0.0015 18.2 0.4 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EON96160.1 - 0.083 12.8 0.2 1.5 8.7 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain TFIIE_alpha PF02002.12 EON96161.1 - 4.1e-17 61.5 0.4 7.9e-17 60.6 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.9 EON96161.1 - 0.0085 15.7 0.6 2.7 7.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS zinc-ribbons_6 PF07191.7 EON96161.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons IER PF05760.7 EON96161.1 - 3.3 7.5 8.3 4.7 7.0 5.7 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Peptidase_S28 PF05577.7 EON96162.1 - 0.082 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Metallophos PF00149.23 EON96164.1 - 1.5e-39 135.5 0.1 2.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EON96164.1 - 1.1e-30 105.5 0.8 2.6e-30 104.2 0.2 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EON96164.1 - 6.4e-23 80.1 7.7 1.9e-17 62.6 1.6 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EON96164.1 - 2.8e-15 55.1 2.4 0.0014 18.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EON96164.1 - 1.6e-11 43.2 1.9 0.03 14.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EON96164.1 - 5.8e-05 22.9 4.0 0.0031 17.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EON96164.1 - 0.0029 18.1 0.1 8.4 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON96164.1 - 0.0033 18.0 2.8 0.48 11.1 1.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EON96164.1 - 0.018 15.3 1.4 20 5.6 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EON96164.1 - 0.024 14.4 0.1 1.5 8.6 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.16 EON96166.1 - 3.8e-49 167.7 0.0 8.1e-49 166.6 0.0 1.5 1 1 0 1 1 1 1 Amidase ABC1 PF03109.11 EON96167.1 - 1e-32 112.6 0.0 2.1e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EON96167.1 - 0.025 13.7 0.0 0.71 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain WaaY PF06176.6 EON96167.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF947 PF06102.7 EON96168.1 - 2.9e-52 176.8 30.7 3.2e-52 176.7 21.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF1848 PF08902.6 EON96168.1 - 0.15 11.5 1.0 0.37 10.2 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) DUF4613 PF15390.1 EON96168.1 - 2.7 6.0 6.9 3.1 5.8 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) tRNA-synt_1c PF00749.16 EON96168.1 - 9.1 4.8 12.3 0.64 8.6 4.7 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain 7tm_2 PF00002.19 EON96169.1 - 8.3e-05 21.7 6.9 8.3e-05 21.7 4.8 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) DUF3455 PF11937.3 EON96170.1 - 2.9e-47 160.8 0.2 3.8e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pkinase PF00069.20 EON96171.1 - 2.3e-51 174.4 0.0 2.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96171.1 - 1.3e-28 99.8 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON96171.1 - 0.11 11.4 0.0 0.48 9.3 0.0 2.0 2 1 0 2 2 2 0 Kinase-like FAD_binding_3 PF01494.14 EON96172.1 - 2.5e-28 99.1 0.0 1e-27 97.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON96172.1 - 5.1e-08 32.2 0.1 8.4e-05 21.6 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON96172.1 - 1.4e-06 27.4 0.1 1.7e-05 23.9 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EON96172.1 - 4.6e-05 23.3 0.1 0.00012 22.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON96172.1 - 8.8e-05 22.6 0.1 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON96172.1 - 0.00021 20.2 1.0 0.013 14.4 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EON96172.1 - 0.00075 19.4 0.1 0.0023 17.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON96172.1 - 0.0029 16.1 0.1 0.017 13.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EON96172.1 - 0.0058 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EON96172.1 - 0.0099 16.2 0.6 0.027 14.8 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EON96172.1 - 0.035 13.7 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EON96172.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EON96172.1 - 0.13 11.0 0.5 0.22 10.3 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EON96172.1 - 0.15 11.8 0.8 5.6 6.7 0.5 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_S9 PF00380.14 EON96173.1 - 4e-36 123.9 0.4 6.6e-36 123.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 QLQ PF08880.6 EON96173.1 - 0.3 10.5 3.9 0.72 9.3 2.7 1.7 1 0 0 1 1 1 0 QLQ Adaptin_N PF01602.15 EON96174.1 - 3.7e-142 474.3 0.5 4.4e-142 474.0 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EON96174.1 - 2e-16 60.2 0.1 5.1e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EON96174.1 - 2.4e-07 30.9 0.6 0.029 14.6 0.0 4.4 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EON96174.1 - 0.00081 19.2 3.2 0.07 12.9 0.9 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EON96174.1 - 0.0036 17.7 3.6 11 6.6 0.0 4.5 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EON96174.1 - 0.0078 16.2 2.1 13 6.1 0.0 4.9 4 1 1 5 5 5 1 HEAT repeat TIP120 PF08623.5 EON96174.1 - 0.017 14.7 0.2 0.094 12.2 0.0 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) RIX1 PF08167.7 EON96174.1 - 0.058 13.0 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis G-patch_2 PF12656.2 EON96174.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DExH-box splicing factor binding site Arm PF00514.18 EON96174.1 - 0.07 12.9 0.2 82 3.2 0.1 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat P5-ATPase PF12409.3 EON96175.1 - 7.1e-37 125.9 0.5 7.2e-36 122.6 0.0 2.5 2 0 0 2 2 2 1 P5-type ATPase cation transporter CMAS PF02353.15 EON96175.1 - 2.1e-35 122.1 0.6 4e-35 121.2 0.4 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase HAD PF12710.2 EON96175.1 - 7.7e-31 107.7 0.0 2.7e-30 105.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EON96175.1 - 9.6e-26 90.2 0.1 3.2e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Methyltransf_11 PF08241.7 EON96175.1 - 6.2e-16 58.6 0.0 1.5e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96175.1 - 1.8e-15 56.8 0.0 4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Hydrolase PF00702.21 EON96175.1 - 5.8e-14 53.0 0.0 6.6e-13 49.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 EON96175.1 - 5.6e-11 42.4 0.0 1.9e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96175.1 - 2.7e-10 40.8 0.0 6.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON96175.1 - 1.6e-08 34.8 0.0 4.2e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON96175.1 - 1.5e-07 31.7 0.0 5.1e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96175.1 - 1.4e-06 27.5 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EON96175.1 - 2.3e-06 27.1 0.0 5.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EON96175.1 - 0.0021 17.6 0.0 0.0064 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF938) PCMT PF01135.14 EON96175.1 - 0.0022 17.5 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cation_ATPase_N PF00690.21 EON96175.1 - 0.0028 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EON96175.1 - 0.0039 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Methyltransf_26 PF13659.1 EON96175.1 - 0.0059 16.6 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON96175.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 EON96175.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TehB PF03848.9 EON96175.1 - 0.18 10.9 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Hydrolase_3 PF08282.7 EON96175.1 - 0.34 10.4 0.0 1.8 8.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF604 PF04646.7 EON96176.1 - 1.2e-09 37.8 0.1 2.9e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 EON96176.1 - 1.6e-05 24.2 0.1 4.1e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Fringe-like RL11D PF11088.3 EON96176.1 - 0.16 11.8 0.3 0.45 10.3 0.2 1.7 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF3309 PF11752.3 EON96176.1 - 0.71 9.6 2.6 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Glyco_hydro_76 PF03663.9 EON96178.1 - 1e-42 146.8 30.2 1.5e-42 146.3 20.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 EON96179.1 - 3.2e-12 45.8 2.0 3.2e-12 45.8 1.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1211 PF06736.6 EON96179.1 - 0.95 9.6 5.5 13 5.9 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) HATPase_c_3 PF13589.1 EON96180.1 - 0.0018 17.9 1.7 0.003 17.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3821 PF12863.2 EON96180.1 - 0.011 15.4 0.3 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Utp11 PF03998.8 EON96180.1 - 0.035 13.9 0.7 0.053 13.3 0.5 1.2 1 0 0 1 1 1 0 Utp11 protein Tom22 PF04281.8 EON96181.1 - 3e-43 146.6 0.1 3.5e-43 146.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Methyltransf_23 PF13489.1 EON96182.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96182.1 - 5.7e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96182.1 - 0.006 17.1 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2422 PF10337.4 EON96183.1 - 6.4e-94 315.3 0.1 6.4e-94 315.3 0.1 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EON96183.1 - 1.2e-18 67.2 14.3 1.2e-18 67.2 9.9 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EON96183.1 - 1.6e-10 40.9 0.0 6.6e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EON96183.1 - 0.00045 18.9 11.3 0.013 14.1 4.9 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF4211 PF13926.1 EON96184.1 - 1e-37 128.9 0.0 9.4e-37 125.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CaM_bdg_C0 PF10562.4 EON96184.1 - 0.56 10.1 4.5 0.32 10.8 1.2 2.1 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Abhydrolase_5 PF12695.2 EON96185.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EON96185.1 - 0.0028 16.1 0.0 0.0085 14.6 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EON96185.1 - 0.0039 16.4 0.0 0.0071 15.6 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EON96185.1 - 0.085 12.0 0.1 0.2 10.8 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1943 PF09172.6 EON96186.1 - 0.004 16.0 1.8 0.0059 15.5 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) HrpB2 PF09487.5 EON96186.1 - 0.052 13.7 1.3 0.11 12.7 0.9 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) GvpL_GvpF PF06386.6 EON96186.1 - 0.053 13.0 9.1 0.084 12.4 6.3 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Oxysterol_BP PF01237.13 EON96186.1 - 4.4 5.7 7.3 6.5 5.1 5.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Aminotran_1_2 PF00155.16 EON96187.1 - 2.5e-60 204.3 0.0 3e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EON96187.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 EON96187.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EON96187.1 - 0.053 11.8 0.0 0.094 10.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EON96187.1 - 0.18 10.7 0.0 0.39 9.7 0.0 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 EON96188.1 - 2.4e-07 30.5 12.1 3.9e-07 29.8 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 EON96189.1 - 1.8e-14 53.4 0.0 2.6e-14 52.9 0.0 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4231 PF14015.1 EON96189.1 - 0.28 11.1 1.4 0.64 10.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ERM PF00769.14 EON96189.1 - 1.1 8.6 12.4 7.2 6.0 8.7 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SAM_2 PF07647.12 EON96191.1 - 4.3e-16 58.5 0.0 8.4e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EON96191.1 - 2e-15 56.6 0.0 3.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EON96191.1 - 7.4e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Dynamin_N PF00350.18 EON96192.1 - 1.4e-16 60.7 1.1 1.4e-15 57.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EON96192.1 - 3e-09 36.8 1.4 8.1e-09 35.4 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EON96192.1 - 2.3e-07 30.4 0.4 4e-06 26.3 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PMEI PF04043.10 EON96192.1 - 0.0049 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor AAA_18 PF13238.1 EON96192.1 - 0.0064 16.7 0.1 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EON96192.1 - 0.025 14.1 0.0 0.078 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MitMem_reg PF13012.1 EON96192.1 - 0.029 14.4 2.9 3.4 7.7 0.2 3.6 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function FH2 PF02181.18 EON96192.1 - 0.043 12.6 3.3 0.041 12.7 0.4 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain Miro PF08477.8 EON96192.1 - 0.082 13.4 0.1 0.85 10.1 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EON96192.1 - 0.39 11.0 4.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.16 EON96193.1 - 8.3e-38 129.4 19.1 1.3e-37 128.7 13.1 1.4 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EON96193.1 - 0.0051 14.7 2.8 0.006 14.5 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EON96193.1 - 0.019 14.3 6.8 0.036 13.4 4.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway HSCB_C PF07743.8 EON96193.1 - 0.019 15.3 2.2 0.019 15.3 1.5 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain CaMBD PF02888.11 EON96193.1 - 0.12 12.1 5.9 0.056 13.2 1.9 2.0 1 1 1 2 2 2 0 Calmodulin binding domain DUF3583 PF12126.3 EON96193.1 - 1 8.3 7.8 1.3 8.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) TMCO5 PF14992.1 EON96193.1 - 5.5 6.0 10.7 29 3.6 7.3 2.0 1 1 0 1 1 1 0 TMCO5 family TMF_DNA_bd PF12329.3 EON96193.1 - 8.1 6.3 10.6 0.67 9.7 3.7 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YlqD PF11068.3 EON96193.1 - 8.4 6.4 18.9 6.1 6.8 4.9 2.2 1 1 1 2 2 2 0 YlqD protein zf-C2H2 PF00096.21 EON96195.1 - 5.6e-06 26.3 3.3 0.023 15.0 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON96195.1 - 0.0016 18.6 4.3 0.054 13.8 0.0 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EON96195.1 - 0.0071 16.4 1.6 2.8 8.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EON96195.1 - 0.12 12.4 1.0 3.5 7.8 0.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EON96195.1 - 0.2 11.6 3.0 4.2 7.4 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger AAA_16 PF13191.1 EON96196.1 - 0.075 13.0 0.1 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DivIC PF04977.10 EON96197.1 - 0.06 12.8 0.3 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.11 EON96198.1 - 4.3e-44 150.6 43.4 4.3e-44 150.6 30.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON96198.1 - 7e-14 50.9 26.0 1e-13 50.4 18.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kinesin PF00225.18 EON96199.1 - 3.2e-115 384.4 0.0 4.3e-115 384.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EON96199.1 - 0.0089 15.8 2.4 0.023 14.5 1.6 1.7 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA PF00004.24 EON96199.1 - 0.033 14.3 2.0 0.43 10.7 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) p450 PF00067.17 EON96201.1 - 5.1e-42 143.9 0.0 1.4e-41 142.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EON96201.1 - 4.6e-19 68.7 0.0 9.1e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON96201.1 - 2.1e-08 34.5 0.0 6.4e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96201.1 - 4.5e-07 30.4 0.0 3e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96201.1 - 7.1e-07 28.9 0.0 7.1e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON96201.1 - 5.8e-05 23.4 0.0 0.00029 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON96201.1 - 7.2e-05 23.0 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96201.1 - 0.00091 18.4 0.0 0.024 13.7 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EON96201.1 - 0.0031 17.5 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NRDD PF13597.1 EON96203.1 - 3.9e-193 642.4 0.0 4.8e-193 642.1 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Radical_SAM PF04055.16 EON96203.1 - 3.1e-16 59.9 0.1 7.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EON96203.1 - 2.8e-09 37.0 0.0 1.3e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EON96203.1 - 1.4e-07 31.6 0.0 5.1e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Pentapeptide_4 PF13599.1 EON96204.1 - 7.3e-05 22.4 1.9 0.069 12.9 0.5 2.7 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EON96204.1 - 0.26 11.2 3.2 35 4.4 1.4 3.3 2 2 2 4 4 4 0 Pentapeptide repeats (9 copies) CfAFP PF05264.6 EON96204.1 - 1.4 8.6 9.5 2.1 8.1 3.4 2.5 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Acetyltransf_1 PF00583.19 EON96206.1 - 2.6e-10 40.1 0.0 1.4e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON96206.1 - 1.8e-07 31.2 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON96206.1 - 3.9e-07 30.1 0.0 1e-06 28.8 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 EON96207.1 - 1.7e-60 203.9 1.5 4.4e-60 202.5 1.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EON96207.1 - 2.4e-45 154.3 4.9 3.7e-45 153.6 1.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EON96207.1 - 2.5e-28 99.9 0.0 1.3e-27 97.6 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON96207.1 - 6.7e-19 67.6 0.0 1.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EON96207.1 - 4.3e-15 56.3 0.0 1.1e-14 55.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EON96207.1 - 2.4e-08 33.3 0.0 1.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EON96207.1 - 1.4e-06 28.1 0.5 5.6e-05 22.8 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EON96208.1 - 1.7e-18 66.5 34.7 1.7e-11 43.4 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AIRC PF00731.15 EON96210.1 - 2.7e-59 198.7 2.4 8e-59 197.2 1.7 1.9 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EON96210.1 - 2.4e-51 173.5 0.0 5.3e-51 172.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EON96210.1 - 3.2e-11 43.3 0.0 1.1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EON96210.1 - 3.1e-08 33.2 0.1 8.5e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 EON96210.1 - 0.00025 21.3 0.5 0.018 15.3 0.1 2.8 3 0 0 3 3 3 1 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 EON96210.1 - 0.00091 18.0 0.0 0.11 11.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 EON96210.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 EON96210.1 - 0.0075 15.6 1.0 0.088 12.2 0.1 2.4 2 0 0 2 2 2 1 Propionate catabolism activator Sugar_tr PF00083.19 EON96211.1 - 8.2e-21 74.0 4.9 9.4e-21 73.8 3.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96211.1 - 8.4e-17 60.9 5.3 1e-16 60.6 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EON96211.1 - 1.2e-06 27.0 0.3 1.3e-06 26.9 0.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EON96211.1 - 0.00019 19.9 4.2 0.00023 19.7 2.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Glyco_hydro_2_C PF02836.12 EON96212.1 - 8.3e-81 271.1 0.2 1.1e-80 270.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EON96212.1 - 1.6e-47 161.2 0.1 2.5e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EON96212.1 - 3.7e-11 43.4 0.0 9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 SKG6 PF08693.5 EON96213.1 - 4.5e-08 32.2 0.5 9.1e-08 31.2 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 EON96213.1 - 0.0044 15.7 4.3 0.0044 15.7 3.0 2.1 1 1 0 2 2 2 1 Giardia variant-specific surface protein MLANA PF14991.1 EON96213.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF4448 PF14610.1 EON96213.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glyco_hydro_12 PF01670.11 EON96214.1 - 2.1e-18 66.6 1.3 5.6e-17 61.9 0.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 SF-assemblin PF06705.6 EON96215.1 - 0.067 12.3 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin MFS_1 PF07690.11 EON96216.1 - 7.4e-07 28.1 36.9 4.7e-06 25.5 23.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON96216.1 - 6.4e-06 24.6 11.2 8.3e-06 24.2 7.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.11 EON96217.1 - 2.1e-27 96.4 0.0 2.6e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.7 EON96218.1 - 1e-124 416.2 0.0 1.2e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 EON96219.1 - 7.5e-13 47.8 0.3 8.4e-13 47.6 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.20 EON96220.1 - 3.3e-15 56.3 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EON96220.1 - 1.5e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON96220.1 - 6.4e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EON96220.1 - 1.7e-06 27.9 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96220.1 - 2.5e-05 24.0 0.3 4e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_9 PF01075.12 EON96220.1 - 0.021 14.0 0.3 0.029 13.5 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) TrkA_N PF02254.13 EON96220.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-Apc11 PF12861.2 EON96221.1 - 2.7 7.9 5.7 0.59 10.0 0.6 2.5 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L14 PF00238.14 EON96222.1 - 1e-32 112.4 0.0 1.2e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short PF00106.20 EON96223.1 - 3.7e-25 88.7 1.9 2.2e-24 86.2 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96223.1 - 6e-13 48.8 0.2 1.6e-12 47.4 0.1 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EON96223.1 - 3.2e-10 40.1 0.7 4.4e-10 39.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON96223.1 - 6e-09 35.6 0.0 8.1e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON96223.1 - 1e-05 25.6 0.5 2.5e-05 24.3 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EON96223.1 - 0.00096 18.2 0.1 0.0017 17.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EON96223.1 - 0.031 14.6 1.9 0.047 14.1 0.7 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 EON96224.1 - 8.8e-56 189.3 0.0 2.4e-54 184.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF2413 PF10310.4 EON96225.1 - 3e-143 477.8 0.0 3.6e-143 477.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EON96225.1 - 0.034 14.1 0.2 0.081 12.9 0.2 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF1313 PF07011.6 EON96225.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) Gly_rich PF12810.2 EON96225.1 - 0.67 9.5 7.4 0.031 13.8 1.2 1.7 2 0 0 2 2 2 0 Glycine rich protein MFS_1 PF07690.11 EON96226.1 - 5.2e-36 124.0 38.8 6.5e-36 123.7 26.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_10 PF13460.1 EON96227.1 - 1.4e-15 57.8 0.2 2e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON96227.1 - 8.2e-06 25.4 0.0 1.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EON96227.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3818 PF12825.2 EON96228.1 - 5.4e-42 143.6 0.2 3e-30 105.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EON96228.1 - 4.2e-30 104.1 0.0 2.6e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 PX-associated DUF3944 PF13099.1 EON96228.1 - 0.027 13.9 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Sugar_tr PF00083.19 EON96229.1 - 4e-75 253.1 22.7 4.6e-75 252.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96229.1 - 1.2e-28 99.8 26.6 1.7e-28 99.3 18.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EON96229.1 - 1.3e-07 30.2 5.1 1e-05 23.9 0.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EON96229.1 - 3.1e-05 22.5 25.7 0.00042 18.8 1.3 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EON96229.1 - 3.1e-05 23.6 4.4 0.13 12.0 1.6 2.7 2 0 0 2 2 2 2 MFS_1 like family HET PF06985.6 EON96230.1 - 4.8e-37 127.2 0.0 8.5e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_US9 PF06072.6 EON96231.1 - 0.026 14.3 1.2 0.045 13.5 0.2 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Aldolase_II PF00596.16 EON96233.1 - 1.2e-37 129.2 0.0 1.5e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Malic_M PF03949.10 EON96234.1 - 1.6e-79 267.0 0.0 2.3e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EON96234.1 - 1.6e-66 223.3 0.0 2.6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AAA PF00004.24 EON96235.1 - 4.7e-16 59.1 0.0 8.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EON96235.1 - 0.021 14.9 0.0 0.057 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EON96235.1 - 0.027 14.1 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EON96235.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glyco_tranf_2_3 PF13641.1 EON96236.1 - 2.7e-36 125.5 0.0 3.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EON96236.1 - 1.1e-19 70.9 0.2 1.1e-19 70.9 0.1 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EON96236.1 - 6e-13 48.4 0.0 9.6e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EON96236.1 - 7.4e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 EON96236.1 - 2.3e-12 46.0 2.6 2.2e-09 36.1 0.4 3.0 1 1 2 3 3 3 2 Cellulose synthase Chitin_synth_2 PF03142.10 EON96236.1 - 0.0086 14.5 0.0 0.073 11.4 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase CDP-OH_P_transf PF01066.16 EON96237.1 - 0.046 14.0 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase DUF1743 PF08489.6 EON96237.1 - 0.14 11.9 0.1 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) ATG27 PF09451.5 EON96239.1 - 4.7e-68 229.3 0.0 5.9e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EON96239.1 - 0.00022 21.0 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat adh_short PF00106.20 EON96240.1 - 4.5e-12 46.1 0.0 6.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96240.1 - 2e-05 24.5 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TAF4 PF05236.9 EON96241.1 - 2.6e-09 36.7 10.8 5e-07 29.2 4.7 3.7 3 1 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family DUF4544 PF15077.1 EON96241.1 - 1.2 8.6 5.7 0.61 9.5 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) CDP-OH_P_transf PF01066.16 EON96242.1 - 2.7e-17 62.9 5.2 2.7e-17 62.9 3.6 1.9 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribonuc_red_lgC PF02867.10 EON96243.1 - 4.3e-224 745.0 0.0 6e-224 744.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EON96243.1 - 2.4e-24 84.9 0.0 5.6e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EON96243.1 - 5.9e-14 52.2 0.1 2.2e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EON96243.1 - 0.049 11.7 0.0 0.082 10.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase VWA_2 PF13519.1 EON96245.1 - 2.4e-09 37.5 0.3 3.2e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EON96245.1 - 8.1e-09 35.4 0.0 2e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EON96245.1 - 7.3e-05 22.6 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Aminotran_3 PF00202.16 EON96246.1 - 5.6e-93 311.4 0.0 6.9e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III BPL_LplA_LipB PF03099.14 EON96247.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Aminotran_1_2 PF00155.16 EON96248.1 - 1.5e-31 109.7 0.0 4.7e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II CPSF73-100_C PF11718.3 EON96249.1 - 5.9e-76 254.6 0.0 1.4e-72 243.5 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EON96249.1 - 1.2e-32 112.4 0.0 4.2e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EON96249.1 - 3.6e-09 36.3 0.1 7.1e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EON96249.1 - 0.00012 21.6 0.0 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EON96249.1 - 0.0019 17.9 1.7 0.0027 17.4 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EON96249.1 - 0.0049 16.5 0.1 0.73 9.4 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Telomere_Sde2_2 PF13297.1 EON96249.1 - 0.095 11.9 0.6 0.4 9.9 0.0 2.3 2 0 0 2 2 2 0 Telomere stability C-terminal A_deaminase PF00962.17 EON96250.1 - 4e-70 236.3 0.0 4.5e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2937 PF11157.3 EON96251.1 - 0.85 8.9 4.6 0.69 9.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Pyridoxal_deC PF00282.14 EON96253.1 - 1.1e-68 231.4 0.0 2.4e-68 230.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Lyase_1 PF00206.15 EON96254.1 - 0.019 14.1 0.2 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 Lyase DUF2029 PF09594.5 EON96254.1 - 0.065 12.7 0.7 3 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) FixQ PF05545.6 EON96254.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LRR_4 PF12799.2 EON96255.1 - 6.4e-31 105.4 29.4 5.8e-07 28.9 1.7 8.6 4 3 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EON96255.1 - 1e-23 82.8 31.2 2.8e-08 33.3 3.5 5.9 4 1 3 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EON96255.1 - 7.1e-16 55.8 36.0 0.097 12.7 0.1 12.5 12 2 0 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 EON96255.1 - 3.2e-08 32.4 43.9 0.76 10.2 0.1 12.1 13 0 0 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 EON96255.1 - 4.7e-06 26.1 32.2 0.96 9.7 0.4 10.5 12 1 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 EON96255.1 - 1.2e-05 24.9 17.4 0.57 9.7 2.5 4.9 1 1 4 5 5 5 4 Leucine-rich repeat DCD PF06559.6 EON96255.1 - 0.015 13.7 0.0 0.047 12.0 0.0 1.7 2 0 0 2 2 2 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Adaptin_N PF01602.15 EON96256.1 - 6.5e-116 387.7 8.2 8e-116 387.4 5.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EON96256.1 - 5.3e-48 161.6 0.0 1.8e-47 159.9 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EON96256.1 - 4.4e-19 68.9 0.0 8.1e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Clathrin PF00637.15 EON96257.1 - 2e-24 85.8 5.3 8.7e-23 80.5 0.7 3.3 2 1 1 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EON96257.1 - 2.6e-21 75.2 0.1 9.9e-21 73.3 0.1 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EON96257.1 - 0.0039 16.9 5.2 0.0084 15.9 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EON96257.1 - 0.0063 16.2 4.9 0.012 15.2 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_14 PF13428.1 EON96257.1 - 0.013 16.0 0.1 17 6.3 0.0 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EON96257.1 - 0.018 14.6 1.4 0.06 13.0 0.0 2.6 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 EON96257.1 - 0.037 13.9 6.2 0.54 10.2 0.0 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EON96257.1 - 0.038 14.3 5.9 1.4 9.2 0.5 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EON96257.1 - 0.063 13.0 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_8 PF13181.1 EON96257.1 - 0.086 12.6 3.8 0.91 9.4 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EON96257.1 - 0.11 12.1 3.1 0.26 10.9 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EON96257.1 - 0.12 12.2 2.3 0.27 11.1 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 EON96257.1 - 0.2 11.6 3.6 0.55 10.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EON96257.1 - 0.21 11.6 8.1 0.12 12.4 2.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EON96257.1 - 0.53 10.4 2.5 1.2 9.3 1.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Het-C PF07217.6 EON96259.1 - 3.3e-288 956.9 0.0 3.8e-288 956.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C P16-Arc PF04699.9 EON96262.1 - 1.4e-38 132.2 0.0 1.6e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) TFIID-18kDa PF02269.11 EON96263.1 - 9.1e-18 63.8 0.0 1.3e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EON96263.1 - 0.00075 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EON96263.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EON96263.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EON96263.1 - 0.063 13.4 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PARP PF00644.15 EON96264.1 - 1.6e-13 50.5 0.0 3.3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EON96264.1 - 1.2e-07 31.2 0.0 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spt20 PF12090.3 EON96265.1 - 1.2e-05 24.6 0.3 1.2e-05 24.6 0.2 6.3 3 1 0 3 3 3 1 Spt20 family XPG_I PF00867.13 EON96266.1 - 6.9e-26 90.1 0.0 5.5e-25 87.2 0.0 2.6 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 EON96266.1 - 3.6e-08 33.6 0.0 8.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PP2C PF00481.16 EON96268.1 - 1.1e-37 129.7 0.1 1.5e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EON96268.1 - 0.00023 20.6 0.0 0.00051 19.5 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C RRM_1 PF00076.17 EON96269.1 - 5e-41 138.1 0.8 1.2e-19 69.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON96269.1 - 4.9e-32 109.7 0.2 9.2e-18 63.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EON96269.1 - 3.8e-30 103.9 0.2 9.4e-30 102.7 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EON96269.1 - 3.3e-19 68.4 0.1 1.3e-08 34.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EON96269.1 - 0.0025 17.6 0.6 0.12 12.2 0.0 3.2 3 1 0 3 3 3 1 RNA binding motif DUF4078 PF13300.1 EON96269.1 - 1.3 9.1 4.1 51 4.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4078) Ala_racemase_N PF01168.15 EON96270.1 - 7.5e-41 140.0 0.1 9.3e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA-synt_2b PF00587.20 EON96271.1 - 2.1e-23 82.8 0.0 2.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EON96271.1 - 2.8e-09 36.9 3.5 1.2e-08 34.9 2.4 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Methyltransf_11 PF08241.7 EON96272.1 - 3.3e-09 37.1 0.0 5.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON96272.1 - 1.2e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON96272.1 - 6.7e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96272.1 - 3.8e-05 23.3 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96272.1 - 0.004 16.2 0.0 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EON96272.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DLH PF01738.13 EON96273.1 - 2.9e-11 43.0 0.2 4.7e-11 42.3 0.1 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family SWIB PF02201.13 EON96274.1 - 3.1e-13 49.1 0.0 5.5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain Mito_carr PF00153.22 EON96275.1 - 3.7e-45 151.5 10.6 2.1e-17 62.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_24 PF13412.1 EON96276.1 - 6.3e-07 28.6 1.7 0.003 16.9 0.0 2.6 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_29 PF13551.1 EON96276.1 - 8.5e-07 29.1 3.2 4.7e-06 26.7 0.7 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EON96276.1 - 1.4e-06 27.7 0.7 0.0047 16.4 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EON96276.1 - 5.1e-06 25.9 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EON96276.1 - 7.3e-06 26.7 5.1 0.0024 18.6 0.9 2.4 1 1 2 3 3 2 2 Homeodomain-like domain HTH_5 PF01022.15 EON96276.1 - 0.00073 19.1 0.2 0.077 12.6 0.2 2.5 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family PAX PF00292.13 EON96276.1 - 0.00077 19.1 0.0 0.0066 16.1 0.0 1.9 1 1 1 2 2 2 1 'Paired box' domain MarR PF01047.17 EON96276.1 - 0.00085 18.9 1.6 2.2 8.0 0.3 3.2 2 1 0 2 2 2 2 MarR family Sigma70_r4 PF04545.11 EON96276.1 - 0.0012 18.1 2.4 0.03 13.6 0.3 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EON96276.1 - 0.0015 17.6 0.0 0.36 10.0 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.2 EON96276.1 - 0.0019 17.8 2.2 1.9 8.1 0.6 3.1 2 1 0 2 2 2 2 MarR family HTH_AsnC-type PF13404.1 EON96276.1 - 0.002 17.5 0.1 0.002 17.5 0.0 2.3 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain GerE PF00196.14 EON96276.1 - 0.0041 16.3 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EON96276.1 - 0.0043 16.4 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.1 EON96276.1 - 0.019 14.9 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Mg_chelatase_2 PF13335.1 EON96276.1 - 0.039 14.3 1.8 1.9 8.9 0.0 2.7 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI YhdB PF14148.1 EON96276.1 - 0.043 13.5 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 YhdB-like protein Herpes_UL6 PF01763.11 EON96276.1 - 0.056 11.6 1.1 0.062 11.4 0.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HTH_11 PF08279.7 EON96276.1 - 0.3 10.7 4.4 5.3 6.7 1.2 2.9 2 1 0 2 2 2 0 HTH domain Sfi1 PF08457.5 EON96277.1 - 9.3e-25 87.0 26.2 1.1e-24 86.7 18.2 1.0 1 0 0 1 1 1 1 Sfi1 spindle body protein V_ATPase_I PF01496.14 EON96278.1 - 2.7e-302 1004.3 0.5 3.1e-302 1004.1 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EON96278.1 - 0.19 11.4 2.0 2 8.0 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DivIC PF04977.10 EON96278.1 - 1.1 8.7 4.7 0.46 9.9 0.1 2.7 3 0 0 3 3 3 0 Septum formation initiator Filament PF00038.16 EON96278.1 - 1.9 7.8 6.3 11 5.3 0.2 2.5 2 1 0 2 2 2 0 Intermediate filament protein ATP-synt_Eps PF04627.8 EON96279.1 - 6.3e-21 73.6 2.6 6.4e-21 73.6 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Tcp11 PF05794.8 EON96280.1 - 4.4e-68 230.0 0.0 1.5e-63 215.0 0.1 2.0 2 0 0 2 2 2 2 T-complex protein 11 Alpha-amylase PF00128.19 EON96281.1 - 1.3e-27 97.0 3.2 2.6e-27 96.0 2.2 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EON96281.1 - 5e-08 31.2 1.1 0.069 10.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EON96281.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Hexapep PF00132.19 EON96283.1 - 5.2e-09 35.2 0.4 0.00011 21.4 0.1 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EON96283.1 - 0.005 16.3 4.1 0.89 9.1 0.1 3.0 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EON96283.1 - 0.12 10.9 0.5 0.2 10.1 0.4 1.3 1 0 0 1 1 1 0 L-fucokinase OMPdecase PF00215.19 EON96284.1 - 1.7e-97 325.2 0.0 2.2e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Uds1 PF15456.1 EON96285.1 - 2.1e-44 150.4 8.9 2.1e-44 150.4 6.2 6.8 3 1 5 8 8 8 2 Up-regulated During Septation IncA PF04156.9 EON96285.1 - 0.0014 18.2 12.6 0.0014 18.2 8.8 7.6 4 2 2 6 6 6 2 IncA protein TMF_DNA_bd PF12329.3 EON96285.1 - 0.0014 18.3 8.6 0.0014 18.3 6.0 8.8 7 2 2 10 10 10 3 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EON96285.1 - 0.0041 16.3 7.9 0.0041 16.3 5.4 4.2 3 1 2 5 5 5 1 Reovirus sigma C capsid protein Img2 PF05046.9 EON96285.1 - 0.044 14.0 2.0 0.39 10.9 0.1 3.2 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Dynactin PF12455.3 EON96286.1 - 1.2e-91 306.4 8.1 1.2e-91 306.4 5.6 3.5 3 0 0 3 3 3 1 Dynein associated protein Glucosaminidase PF01832.15 EON96286.1 - 0.039 14.0 0.8 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase TatD_DNase PF01026.16 EON96287.1 - 2.1e-49 168.0 0.2 5.7e-49 166.6 0.2 1.6 1 1 0 1 1 1 1 TatD related DNase tRNA-synt_1 PF00133.17 EON96288.1 - 6.4e-219 727.9 0.0 9.6e-219 727.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EON96288.1 - 5.7e-26 91.1 0.0 2.3e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EON96288.1 - 4.5e-17 61.7 0.1 5.4e-06 25.3 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EON96288.1 - 0.016 14.3 0.0 0.053 12.6 0.0 1.9 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EON96288.1 - 0.037 13.3 0.2 0.088 12.0 0.1 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CFEM PF05730.6 EON96291.1 - 4.2e-13 48.9 7.7 7.8e-13 48.0 5.4 1.4 1 0 0 1 1 1 1 CFEM domain KOW PF00467.24 EON96292.1 - 1.8e-07 30.5 1.3 5.7e-07 29.0 0.9 1.9 1 0 0 1 1 1 1 KOW motif DUF2120 PF09893.4 EON96292.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) bZIP_2 PF07716.10 EON96293.1 - 1.8e-11 43.7 12.1 3.1e-11 42.9 8.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EON96293.1 - 0.00013 21.8 10.8 0.00029 20.7 7.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EON96293.1 - 0.011 15.6 4.0 0.011 15.6 2.8 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF2968 PF11180.3 EON96293.1 - 0.011 15.0 4.4 0.021 14.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TSC22 PF01166.13 EON96293.1 - 0.12 12.3 1.3 0.27 11.2 0.9 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Syntaxin PF00804.20 EON96293.1 - 0.24 11.6 7.1 0.42 10.7 4.9 1.5 1 1 0 1 1 1 0 Syntaxin IncA PF04156.9 EON96293.1 - 3.3 7.2 4.8 4.9 6.7 3.3 1.2 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 EON96294.1 - 2.7e-10 40.0 8.0 6.1e-10 38.9 5.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EON96294.1 - 0.0003 20.5 8.3 0.0003 20.5 5.7 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 EON96294.1 - 2.5 7.6 10.4 1.2 8.6 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator ECH PF00378.15 EON96295.1 - 1.1e-20 73.8 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EON96295.1 - 0.001 18.8 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 PHD PF00628.24 EON96296.1 - 5.1e-10 38.8 8.3 8.4e-10 38.1 5.8 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EON96296.1 - 6e-08 32.9 3.5 1.2e-07 31.9 0.1 2.8 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EON96296.1 - 0.022 14.9 1.8 0.054 13.6 1.3 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain LPP20 PF02169.11 EON96296.1 - 0.93 9.6 8.3 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 LPP20 lipoprotein PBP1_TM PF14812.1 EON96296.1 - 1.1 9.6 7.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M16 PF00675.15 EON96297.1 - 2.4e-18 66.3 0.1 4.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EON96297.1 - 3.2e-16 59.5 0.0 6.9e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain BMC PF00936.14 EON96297.1 - 0.041 13.5 1.5 0.079 12.6 0.2 2.1 2 0 0 2 2 2 0 BMC domain DUF3568 PF12092.3 EON96297.1 - 0.068 12.8 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) MscS_porin PF12795.2 EON96298.1 - 0.0044 16.3 7.4 0.0078 15.5 5.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Replicase PF03090.12 EON96298.1 - 0.02 14.7 0.0 0.077 12.8 0.0 1.8 1 1 1 2 2 2 0 Replicase family DUF4407 PF14362.1 EON96298.1 - 0.068 12.1 2.5 0.095 11.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF869 PF05911.6 EON96298.1 - 0.27 9.4 9.0 0.46 8.6 6.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Nsp1_C PF05064.8 EON96298.1 - 4.8 6.8 10.7 0.13 11.8 2.8 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region IncA PF04156.9 EON96298.1 - 5.3 6.5 13.5 14 5.2 9.4 1.6 1 0 0 1 1 1 0 IncA protein FTR1 PF03239.9 EON96299.1 - 5.1e-79 265.3 10.3 6e-79 265.1 7.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 EON96299.1 - 0.02 14.8 0.3 0.02 14.8 0.2 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Mak10 PF04112.8 EON96300.1 - 7.4e-21 74.0 0.0 1.1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TIP49 PF06068.8 EON96301.1 - 7.9e-185 614.2 0.3 9.1e-185 614.0 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EON96301.1 - 3e-11 43.6 0.2 8.6e-07 29.2 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EON96301.1 - 4.5e-10 38.9 0.4 8.5e-07 28.2 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EON96301.1 - 2.4e-05 23.9 0.1 7.5e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EON96301.1 - 4.4e-05 23.6 0.3 0.16 12.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EON96301.1 - 0.00047 20.1 0.0 0.013 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EON96301.1 - 0.0007 19.5 0.1 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EON96301.1 - 0.0015 17.9 0.0 0.0074 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EON96301.1 - 0.0027 17.4 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EON96301.1 - 0.006 15.7 0.3 0.015 14.4 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EON96301.1 - 0.0075 15.4 0.2 0.31 10.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EON96301.1 - 0.011 15.1 0.2 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EON96301.1 - 0.013 15.0 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EON96301.1 - 0.018 15.3 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EON96301.1 - 0.023 13.5 0.0 0.056 12.3 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 EON96301.1 - 0.024 13.6 0.1 0.074 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EON96301.1 - 0.077 13.8 0.1 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cupin_2 PF07883.6 EON96302.1 - 2.3e-07 30.2 0.0 4.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EON96302.1 - 0.081 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CN_hydrolase PF00795.17 EON96303.1 - 1.3e-16 60.4 0.0 3.3e-12 46.1 0.0 2.6 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase RTA1 PF04479.8 EON96305.1 - 5.2e-05 22.8 3.7 0.00028 20.4 2.6 2.0 1 1 0 1 1 1 1 RTA1 like protein DUF4096 PF13340.1 EON96305.1 - 0.018 14.8 0.0 5 7.0 0.0 2.4 1 1 1 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) Cu-oxidase_2 PF07731.9 EON96306.1 - 5.8e-40 135.9 1.2 8.2e-36 122.5 0.2 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EON96306.1 - 1.4e-39 135.5 0.2 3.8e-36 124.3 0.1 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EON96306.1 - 2.8e-24 85.1 2.1 2.5e-20 72.3 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EON96306.1 - 0.00054 19.8 0.0 10 6.0 0.0 3.7 3 0 0 3 3 3 2 Cupredoxin-like domain Pkinase PF00069.20 EON96307.1 - 1.3e-52 178.4 0.1 5.9e-37 127.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EON96307.1 - 2e-21 76.2 0.0 3.4e-11 42.6 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EON96307.1 - 7.1e-06 25.1 0.0 1.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON96307.1 - 0.00015 21.5 1.2 0.0026 17.5 0.8 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mito_carr PF00153.22 EON96308.1 - 1.2e-29 101.8 0.6 4e-15 55.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EON96309.1 - 5e-10 38.6 0.0 9e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON96309.1 - 2.3e-07 30.5 12.6 3.8e-07 29.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.1 EON96310.1 - 0.01 15.8 0.0 9.2 6.6 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.2 EON96310.1 - 0.011 15.4 0.3 0.047 13.4 0.0 2.3 2 0 0 2 2 2 0 F-box-like LRR_7 PF13504.1 EON96310.1 - 0.062 13.5 0.9 99 3.8 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat Glycos_transf_1 PF00534.15 EON96311.1 - 3.4e-32 111.2 0.0 5.9e-31 107.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EON96311.1 - 2.4e-09 37.5 0.0 2.4e-09 37.5 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EON96311.1 - 1.1e-08 35.0 0.0 9.5e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EON96311.1 - 1.7e-08 34.7 0.3 6.3e-07 29.6 0.2 2.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EON96311.1 - 0.00025 21.2 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DOCK-C2 PF14429.1 EON96312.1 - 2.3e-21 76.2 0.0 4.2e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EON96312.1 - 5.6e-09 35.5 0.2 1.8e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EON96312.1 - 5.3e-06 25.7 0.0 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON96312.1 - 0.00019 20.9 0.1 0.00085 18.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EON96312.1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.8 1 1 0 1 1 1 0 Variant SH3 domain Mito_carr PF00153.22 EON96313.1 - 4.8e-52 173.6 2.5 1.3e-16 60.0 0.4 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EON96313.1 - 0.001 18.8 0.1 0.003 17.3 0.1 1.9 1 0 0 1 1 1 1 UcrQ family DUF2590 PF10761.4 EON96313.1 - 0.079 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Abhydrolase_3 PF07859.8 EON96314.1 - 7.1e-36 123.7 0.0 2e-25 89.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EON96314.1 - 0.019 14.6 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 EON96314.1 - 0.047 12.3 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) SRP19 PF01922.12 EON96315.1 - 1.6e-29 102.2 0.0 2.9e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Integrase_Zn PF02022.14 EON96315.1 - 0.024 14.0 0.1 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain RNA_pol_Rpc82 PF05645.8 EON96316.1 - 2.7e-46 158.2 0.0 1.2e-45 156.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EON96316.1 - 3.8e-19 68.3 0.1 2.7e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EON96316.1 - 2.2e-05 23.8 1.0 0.012 15.0 0.0 3.5 3 1 0 3 3 3 2 TFIIE alpha subunit zf-C2H2 PF00096.21 EON96317.1 - 1.3e-06 28.3 13.9 0.0031 17.7 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON96317.1 - 1.6e-05 24.8 11.3 0.0082 16.4 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EON96317.1 - 2.1 8.8 14.1 0.064 13.5 2.7 3.0 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.11 EON96318.1 - 7.4e-16 57.8 27.8 7.4e-16 57.8 19.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EON96318.1 - 0.00012 21.3 3.7 0.00012 21.3 2.6 2.8 2 1 0 2 2 2 1 Nodulin-like DUF4131 PF13567.1 EON96318.1 - 1.5 8.2 0.0 1.5 8.2 0.0 4.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4131) Mo25 PF08569.6 EON96319.1 - 3.5e-118 394.4 0.0 3.8e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Mo25-like BLOC1_2 PF10046.4 EON96320.1 - 0.19 11.8 0.2 0.9 9.7 0.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cyt-b5 PF00173.23 EON96321.1 - 2.2e-20 72.2 0.8 5.8e-20 70.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EON96321.1 - 1.2e-07 32.1 21.2 1.6e-07 31.6 14.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EON96321.1 - 0.029 14.3 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 EON96321.1 - 0.029 13.9 0.3 0.077 12.6 0.2 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly MS_channel PF00924.13 EON96322.1 - 1.1e-18 67.3 2.7 2.6e-18 66.1 1.9 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EON96322.1 - 0.015 14.5 0.2 0.015 14.5 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EON96322.1 - 0.019 14.7 0.0 0.089 12.7 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EON96322.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EON96322.1 - 0.06 12.7 0.1 0.06 12.7 0.1 2.0 2 0 0 2 2 2 0 EF hand VIT1 PF01988.14 EON96322.1 - 2 7.8 8.9 0.076 12.4 0.2 2.5 2 0 0 2 2 2 0 VIT family Chorismate_synt PF01264.16 EON96323.1 - 3.2e-128 427.0 0.0 4.6e-128 426.5 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase Glyco_hydro_12 PF01670.11 EON96324.1 - 1.2e-34 119.3 2.0 1.2e-34 119.3 1.4 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EON96324.1 - 1.6 8.9 7.0 0.28 11.3 0.8 2.4 1 1 1 2 2 2 0 Phage holin CTP_transf_2 PF01467.21 EON96325.1 - 0.016 15.2 0.8 0.023 14.7 0.5 1.2 1 0 0 1 1 1 0 Cytidylyltransferase HALZ PF02183.13 EON96325.1 - 0.029 14.0 0.6 0.029 14.0 0.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper G-gamma PF00631.17 EON96325.1 - 0.035 13.8 1.5 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 GGL domain Jnk-SapK_ap_N PF09744.4 EON96325.1 - 1.4 8.9 11.0 0.081 12.9 2.3 2.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-ribbon_3 PF13248.1 EON96327.1 - 0.0068 15.5 5.1 0.26 10.5 0.9 2.6 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 EON96327.1 - 0.013 15.3 2.8 3.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Double zinc ribbon RRN7 PF11781.3 EON96327.1 - 0.16 11.4 3.9 1.5 8.3 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glyco_hydro_28 PF00295.12 EON96328.1 - 2.6e-07 29.9 2.7 5e-07 28.9 1.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EON96328.1 - 2.1e-05 24.3 11.4 0.006 16.3 5.8 2.8 1 1 1 2 2 2 2 Right handed beta helix region OstA_2 PF13100.1 EON96328.1 - 0.069 12.4 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 OstA-like protein TFR_dimer PF04253.10 EON96329.1 - 2.1e-23 82.2 0.1 7.4e-23 80.4 0.0 2.0 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EON96329.1 - 1e-18 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EON96329.1 - 2.1e-05 24.1 0.1 4.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 PA domain Atu4866 PF11512.3 EON96329.1 - 0.012 15.3 0.0 0.67 9.7 0.0 2.6 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 Nicastrin PF05450.10 EON96329.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin PAT1 PF09770.4 EON96331.1 - 1.4e-238 794.2 9.8 1.7e-238 794.0 6.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GDH_N PF12466.3 EON96331.1 - 0.025 14.5 2.8 0.061 13.3 1.9 1.7 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal DUF3129 PF11327.3 EON96332.1 - 1.6e-71 239.8 13.3 2.1e-71 239.5 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) MFS_1 PF07690.11 EON96333.1 - 9.8e-25 86.9 50.4 5.6e-16 58.1 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EON96333.1 - 0.33 10.9 11.9 0.73 9.9 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) HAD PF12710.2 EON96334.1 - 4.1e-14 53.2 0.0 5.9e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EON96334.1 - 0.0073 16.5 0.0 0.025 14.8 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EON96334.1 - 0.017 14.3 0.1 0.17 11.0 0.1 2.1 1 1 0 1 1 1 0 Putative Phosphatase UMPH-1 PF05822.7 EON96334.1 - 0.055 12.7 0.0 0.12 11.7 0.0 1.6 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Sec62 PF03839.11 EON96335.1 - 1.9e-53 181.1 0.8 1.9e-53 181.1 0.6 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 HicB PF05534.7 EON96335.1 - 0.12 12.0 0.0 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 HicB family Adaptin_N PF01602.15 EON96336.1 - 2.6e-103 346.1 0.0 2.9e-103 345.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EON96336.1 - 6.4e-15 55.2 1.3 8.1e-06 26.0 0.0 4.7 3 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EON96336.1 - 4.6e-10 38.7 0.1 0.038 14.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EON96336.1 - 4.4e-07 30.1 5.6 0.0016 18.9 0.0 5.5 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EON96336.1 - 0.00011 22.0 0.1 0.071 13.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EON96336.1 - 0.028 14.2 0.0 1.6 8.5 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 EON96336.1 - 0.039 13.5 0.3 16 5.1 0.0 3.1 3 0 0 3 3 3 0 VHS domain CLASP_N PF12348.3 EON96336.1 - 0.069 12.4 0.2 6.8 5.9 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal PPP4R2 PF09184.6 EON96336.1 - 2.5 7.5 12.8 27 4.1 10.5 1.5 2 0 0 2 2 2 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.3 EON96336.1 - 6.2 6.6 18.0 11 5.9 12.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.7 EON96336.1 - 8.4 5.5 22.3 13 4.9 15.5 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EON96336.1 - 9.6 5.1 13.8 14 4.5 9.6 1.1 1 0 0 1 1 1 0 BUD22 TFIIB PF00382.14 EON96338.1 - 3.6e-26 90.7 0.7 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EON96338.1 - 8.5e-20 70.7 5.4 8.5e-20 70.7 3.8 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EON96338.1 - 2.3e-05 23.9 0.2 0.02 14.4 0.0 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cut8_N PF14482.1 EON96338.1 - 2.7 8.0 15.3 0.31 11.0 0.6 3.1 3 1 0 3 3 3 0 Cut8 proteasome-binding domain Ribosom_S12_S23 PF00164.20 EON96339.1 - 1.7e-39 134.0 0.7 1.9e-39 133.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Fungal_trans_2 PF11951.3 EON96340.1 - 5.8e-06 25.1 0.4 1e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase_2 PF07731.9 EON96341.1 - 2.3e-39 134.0 0.1 7.5e-38 129.1 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EON96341.1 - 2.8e-34 118.3 0.2 6.2e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase AA_permease_2 PF13520.1 EON96342.1 - 2.7e-09 36.1 10.9 3.3e-09 35.7 7.6 1.1 1 0 0 1 1 1 1 Amino acid permease Neurensin PF14927.1 EON96342.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Neurensin DUF805 PF05656.9 EON96342.1 - 2.9 7.7 8.9 0.49 10.2 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF1129 PF06570.6 EON96342.1 - 6.5 5.9 8.7 7.4 5.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MpPF26 PF07666.6 EON96342.1 - 8.9 6.2 11.1 2.8 7.8 2.6 2.0 1 1 1 2 2 2 0 M penetrans paralogue family 26 KilA-N PF04383.8 EON96343.1 - 0.035 13.7 0.0 0.31 10.6 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain DUF917 PF06032.7 EON96344.1 - 3.2e-94 315.3 1.8 5.3e-94 314.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EON96344.1 - 1.7e-09 37.1 0.8 8.4e-09 34.9 0.1 2.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase EBP PF05241.7 EON96345.1 - 9.5e-48 161.7 4.0 1.1e-47 161.6 2.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein YMF19 PF02326.10 EON96345.1 - 0.72 10.4 4.2 4.6 7.8 0.1 2.3 1 1 0 2 2 2 0 Plant ATP synthase F0 DUF924 PF06041.6 EON96346.1 - 2.6e-18 66.4 0.0 5.1e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Lipase_GDSL PF00657.17 EON96347.1 - 3.4e-16 59.7 1.3 4.5e-16 59.4 0.9 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lon_C PF05362.8 EON96348.1 - 4e-65 218.9 0.0 7.2e-65 218.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EON96348.1 - 5.7e-35 120.8 2.4 1.9e-34 119.1 1.7 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EON96348.1 - 4.2e-22 78.7 0.0 1.5e-21 76.9 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EON96348.1 - 6.8e-08 32.0 0.1 2.1e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EON96348.1 - 4.9e-07 29.8 0.0 2.8e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EON96348.1 - 5.1e-07 29.4 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EON96348.1 - 1.6e-05 25.0 0.0 0.00034 20.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EON96348.1 - 5.2e-05 22.1 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EON96348.1 - 9.6e-05 23.1 0.0 0.00041 21.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EON96348.1 - 0.00012 21.2 0.1 0.0012 17.9 0.0 2.5 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EON96348.1 - 0.00071 19.6 2.7 0.0054 16.7 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EON96348.1 - 0.0038 17.1 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EON96348.1 - 0.006 16.8 0.4 0.028 14.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EON96348.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EON96348.1 - 0.026 14.0 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EON96348.1 - 0.031 14.4 0.0 0.13 12.4 0.0 2.2 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EON96348.1 - 0.031 13.6 0.1 0.094 12.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EON96348.1 - 0.042 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EON96348.1 - 0.077 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EON96348.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EON96348.1 - 0.93 9.7 4.5 0.72 10.1 0.0 2.8 3 0 0 3 3 3 0 ABC transporter PI31_Prot_C PF08577.6 EON96349.1 - 2.8e-18 66.3 18.2 2.8e-18 66.3 12.6 3.1 3 1 1 4 4 4 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 EON96349.1 - 2.3e-10 40.2 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PLDc_2 PF13091.1 EON96350.1 - 4.3e-14 52.3 0.0 1.8e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EON96350.1 - 2.4e-12 46.2 1.0 1.3e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_76 PF03663.9 EON96352.1 - 1.4e-127 426.1 10.1 1.8e-127 425.8 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HAD_2 PF13419.1 EON96353.1 - 2.6e-26 92.8 0.1 3e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON96353.1 - 2.5e-06 28.0 0.0 2.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribonuclease_T2 PF00445.13 EON96354.1 - 7.3e-20 71.3 0.0 8.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family FA_hydroxylase PF04116.8 EON96355.1 - 7.2e-06 26.3 1.8 7.2e-06 26.3 1.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mpv17_PMP22 PF04117.7 EON96356.1 - 1.7e-24 85.2 1.5 2.3e-23 81.5 0.1 2.6 3 1 0 3 3 3 1 Mpv17 / PMP22 family Pkinase PF00069.20 EON96357.1 - 1.6e-14 53.7 1.3 1.5e-13 50.4 0.3 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96357.1 - 3.2e-14 52.6 0.0 4.6e-13 48.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PLAC8 PF04749.12 EON96358.1 - 3.4e-23 82.2 9.6 4.2e-23 81.9 6.6 1.1 1 0 0 1 1 1 1 PLAC8 family DSS1_SEM1 PF05160.8 EON96359.1 - 2e-24 85.1 17.7 2.9e-24 84.6 12.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Nuf2 PF03800.9 EON96360.1 - 4.8e-43 146.6 0.1 4.8e-43 146.6 0.0 2.4 3 1 0 3 3 3 1 Nuf2 family DUF3584 PF12128.3 EON96360.1 - 0.0032 14.8 38.2 0.006 13.9 26.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SPATA19 PF15212.1 EON96360.1 - 0.14 12.2 8.3 0.47 10.5 5.7 1.9 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Reo_sigmaC PF04582.7 EON96360.1 - 0.3 10.2 10.2 0.71 8.9 3.9 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein eIF-1a PF01176.14 EON96361.1 - 1.1e-17 63.1 0.0 1.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TTKRSYEDQ PF10212.4 EON96362.1 - 0.13 11.1 0.7 0.2 10.5 0.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Cytochrom_C PF00034.16 EON96362.1 - 8.6 7.2 11.2 0.79 10.5 1.7 3.5 3 1 0 3 3 3 0 Cytochrome c PGK PF00162.14 EON96363.1 - 3.6e-152 506.3 0.7 4.1e-152 506.2 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peripla_BP_4 PF13407.1 EON96363.1 - 0.0026 17.1 1.7 0.006 15.9 1.2 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain PA PF02225.17 EON96363.1 - 0.0075 15.9 0.3 0.2 11.3 0.0 2.7 2 0 0 2 2 2 1 PA domain FIVAR PF07554.8 EON96363.1 - 0.28 11.4 5.3 9.6 6.5 0.0 4.0 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Inositol_P PF00459.20 EON96364.1 - 1.1e-34 120.0 0.0 2.2e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Metallophos PF00149.23 EON96365.1 - 1.4e-41 142.1 0.9 1.7e-41 141.8 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB PF00651.26 EON96366.1 - 1.6e-07 31.2 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.17 EON96366.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Skp1_POZ PF03931.10 EON96366.1 - 0.089 12.9 0.0 5.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain Glyco_transf_15 PF01793.11 EON96367.1 - 8.2e-143 475.2 5.1 9.7e-143 475.0 3.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 EON96367.1 - 0.0091 15.7 0.6 0.0091 15.7 0.4 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Vps35 PF03635.12 EON96368.1 - 3.1e-293 974.6 0.3 1.4e-176 588.9 0.1 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 35 Cupin_1 PF00190.17 EON96369.1 - 7e-31 106.5 0.0 5e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EON96369.1 - 2.8e-24 84.4 2.4 7.1e-13 47.8 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EON96369.1 - 2.6e-07 29.9 0.1 0.0086 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EON96369.1 - 0.00011 21.9 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EON96369.1 - 0.0033 17.1 0.7 1 9.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Thioredoxin PF00085.15 EON96370.1 - 1.9e-41 139.9 0.0 2.8e-24 84.8 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EON96370.1 - 4.3e-13 49.4 0.0 6.1e-06 26.1 0.0 4.6 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EON96370.1 - 7.9e-08 32.3 0.4 0.0017 18.4 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EON96370.1 - 2.7e-07 30.7 5.0 0.0059 16.7 0.0 4.8 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EON96370.1 - 6.3e-06 26.1 0.1 0.0058 16.6 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EON96370.1 - 0.0075 16.1 0.0 8.4 6.3 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE 7TM_GPCR_Srh PF10318.4 EON96370.1 - 0.029 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh AhpC-TSA PF00578.16 EON96370.1 - 0.03 14.0 2.2 1.7 8.3 0.0 3.3 2 1 1 3 3 3 0 AhpC/TSA family Thioredoxin_3 PF13192.1 EON96370.1 - 0.041 13.6 0.0 6.1 6.7 0.0 3.9 4 1 0 4 4 4 0 Thioredoxin domain TraF PF13728.1 EON96370.1 - 0.06 12.8 0.1 0.6 9.5 0.0 2.4 3 0 0 3 3 3 0 F plasmid transfer operon protein TrbC_Ftype PF09673.5 EON96370.1 - 0.18 11.4 0.3 2 8.0 0.0 2.6 2 1 1 3 3 3 0 Type-F conjugative transfer system pilin assembly protein HsbA PF12296.3 EON96372.1 - 2.9e-25 88.5 6.5 2.9e-25 88.5 4.5 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Peptidase_S24 PF00717.18 EON96373.1 - 1.9e-07 30.6 0.0 2.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Ldh_2 PF02615.9 EON96374.1 - 1.5e-98 329.6 0.0 1.7e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF3808 PF10300.4 EON96375.1 - 1.3e-123 413.0 0.0 1.7e-123 412.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EON96375.1 - 0.00019 21.6 3.8 0.5 10.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON96375.1 - 0.0037 17.8 4.6 0.5 11.1 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1039 PF06287.6 EON96375.1 - 0.05 13.4 0.3 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) TPR_14 PF13428.1 EON96375.1 - 0.19 12.4 4.5 1.5 9.6 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Amidase PF01425.16 EON96376.1 - 2.3e-86 290.4 0.0 2.8e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Amidase IBN_N PF03810.14 EON96377.1 - 1.7e-12 47.0 0.0 7.7e-11 41.7 0.0 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EON96377.1 - 0.0034 17.3 0.9 0.41 10.5 0.0 4.2 5 0 0 5 5 5 1 Exportin 1-like protein Cse1 PF08506.5 EON96377.1 - 0.02 13.4 0.0 1 7.8 0.0 2.3 2 0 0 2 2 2 0 Cse1 DNA_topoisoIV PF00521.15 EON96378.1 - 1.6e-120 402.8 0.6 4.4e-120 401.4 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EON96378.1 - 4.2e-33 114.0 2.1 8.6e-33 112.9 1.5 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EON96378.1 - 8.7e-13 48.1 0.0 3.3e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EON96378.1 - 6.6e-11 41.9 0.1 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AT_hook PF02178.14 EON96378.1 - 4.2 7.3 14.4 9.6 6.2 3.3 3.3 2 0 0 2 2 2 0 AT hook motif RTA1 PF04479.8 EON96379.1 - 2.5e-41 141.6 2.0 3.2e-41 141.2 1.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3899 PF13038.1 EON96379.1 - 0.11 12.7 0.1 0.11 12.7 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) Abhydrolase_9_N PF15420.1 EON96379.1 - 1.2 8.7 4.8 0.32 10.6 0.4 2.0 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF4052 PF13261.1 EON96379.1 - 2.6 7.4 5.7 0.91 8.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4052) G_glu_transpept PF01019.16 EON96380.1 - 5e-77 259.5 0.1 5.5e-77 259.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HORMA PF02301.13 EON96383.1 - 3.7e-15 55.9 0.0 8.9e-09 35.1 0.0 2.6 2 1 0 2 2 2 2 HORMA domain Daxx PF03344.10 EON96383.1 - 0.048 12.1 7.5 0.06 11.8 5.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 EON96383.1 - 0.08 12.1 1.6 0.14 11.3 1.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 EON96383.1 - 0.46 8.3 11.0 0.57 8.0 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EON96383.1 - 1.1 8.8 11.4 1.6 8.3 7.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 EON96383.1 - 1.6 7.7 12.5 2.2 7.2 8.7 1.1 1 0 0 1 1 1 0 BUD22 Med17 PF10156.4 EON96383.1 - 6.3 4.9 5.4 9.1 4.4 3.8 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex KH_1 PF00013.24 EON96384.1 - 1.9e-23 81.8 2.4 1.6e-07 30.8 0.1 6.8 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EON96384.1 - 8.9e-17 60.3 9.1 9.2e-05 22.0 0.2 5.4 6 0 0 6 6 6 4 KH domain Abhydrolase_6 PF12697.2 EON96385.1 - 1.1e-05 25.4 0.1 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96385.1 - 0.00029 20.6 0.0 0.00047 19.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EON96385.1 - 0.0081 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EON96385.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF4661 PF15576.1 EON96385.1 - 0.019 14.6 3.0 0.028 14.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Host_attach PF10116.4 EON96385.1 - 0.44 10.7 6.5 0.1 12.8 0.6 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells PBP PF01161.15 EON96386.1 - 3.8e-16 59.2 0.0 4.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sugar_tr PF00083.19 EON96387.1 - 4.3e-100 335.4 23.0 4.9e-100 335.2 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96387.1 - 7.2e-25 87.4 30.0 7.7e-19 67.6 5.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON96387.1 - 0.0013 17.1 27.0 0.0042 15.5 4.3 3.0 2 2 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 EON96387.1 - 1.3 7.0 11.2 4.5 5.1 2.1 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Med21 PF11221.3 EON96388.1 - 5e-46 156.2 7.2 5.5e-46 156.1 5.0 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 EON96388.1 - 0.00054 19.2 5.8 0.1 11.7 1.9 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.8 EON96388.1 - 0.0038 16.9 1.2 0.0038 16.9 0.8 3.1 3 1 1 4 4 4 2 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.1 EON96388.1 - 0.007 16.4 5.3 0.007 16.4 3.6 1.7 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EON96388.1 - 0.011 15.4 8.4 0.011 15.4 5.8 1.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EON96388.1 - 0.047 13.8 4.1 0.065 13.3 1.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EON96388.1 - 0.12 12.0 4.8 0.12 12.0 2.1 1.8 2 1 0 2 2 2 0 Mnd1 family DUF3802 PF12290.3 EON96388.1 - 0.16 12.2 3.0 0.36 11.1 1.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) APG6 PF04111.7 EON96388.1 - 1.3 7.9 7.0 1.6 7.6 4.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 TRI12 PF06609.8 EON96390.1 - 3.5e-08 32.1 14.8 4.5e-08 31.7 10.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON96390.1 - 0.01 14.5 50.4 0.093 11.4 23.8 3.2 1 1 2 3 3 3 0 Major Facilitator Superfamily Pox_A14 PF05767.7 EON96390.1 - 0.025 14.5 1.6 0.025 14.5 1.1 2.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3959 PF13105.1 EON96390.1 - 0.27 10.5 9.9 0.018 14.3 2.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3959) DUF872 PF05915.7 EON96390.1 - 1.1 9.1 4.7 0.7 9.7 0.4 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Herpes_LMP1 PF05297.6 EON96390.1 - 7.7 5.3 10.5 12 4.6 7.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CcmD PF04995.9 EON96390.1 - 9.2 6.0 9.4 0.55 10.0 1.1 3.0 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) She9_MDM33 PF05546.6 EON96391.1 - 3.6e-77 258.6 4.6 5.2e-77 258.0 3.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family BCAS2 PF05700.6 EON96391.1 - 0.0083 15.6 1.5 0.0083 15.6 1.0 2.2 2 1 0 3 3 3 1 Breast carcinoma amplified sequence 2 (BCAS2) FliD_N PF02465.13 EON96391.1 - 0.019 15.2 1.2 0.77 10.1 0.8 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Serine_rich PF08824.5 EON96391.1 - 0.028 14.1 2.8 3.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain OmpH PF03938.9 EON96391.1 - 0.078 12.9 2.1 0.19 11.6 1.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Filament PF00038.16 EON96391.1 - 0.18 11.2 4.2 0.072 12.5 0.7 1.8 2 0 0 2 2 2 0 Intermediate filament protein LMP PF04778.7 EON96391.1 - 0.44 10.2 3.2 0.37 10.5 0.6 2.1 3 0 0 3 3 3 0 LMP repeated region TMF_TATA_bd PF12325.3 EON96391.1 - 0.58 9.8 3.8 1.4 8.6 0.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sugar_tr PF00083.19 EON96392.1 - 1.3e-68 231.5 16.3 1.5e-68 231.4 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96392.1 - 5.5e-20 71.3 12.9 7.9e-20 70.8 9.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tmemb_170 PF10190.4 EON96392.1 - 0.04 13.9 1.4 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 Thioredoxin PF00085.15 EON96393.1 - 5.3e-28 96.7 0.0 6.4e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EON96393.1 - 2.3e-06 27.7 0.1 6.1e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EON96393.1 - 1.1e-05 25.4 0.1 0.0029 17.6 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EON96393.1 - 1.2e-05 24.8 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EON96393.1 - 0.00044 19.0 0.0 0.00054 18.7 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 EON96393.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.5 EON96393.1 - 0.0034 16.9 0.4 0.55 9.7 0.2 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EON96393.1 - 0.0056 16.6 0.1 0.0087 16.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EON96393.1 - 0.028 14.0 0.1 0.11 12.1 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family Glutaredoxin PF00462.19 EON96393.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin DUF836 PF05768.9 EON96393.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PAP_central PF04928.12 EON96394.1 - 3.2e-24 85.1 0.0 5.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EON96394.1 - 1e-10 41.9 0.0 2.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EON96394.1 - 7.6e-10 38.8 0.2 1.5e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) 2_5_RNA_ligase2 PF13563.1 EON96394.1 - 0.00021 21.0 0.0 0.00047 19.8 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily NTP_transf_2 PF01909.18 EON96394.1 - 0.00034 20.8 0.0 0.00088 19.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 EON96394.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nop14 PF04147.7 EON96394.1 - 3 5.6 6.8 4.1 5.2 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1349 PF07081.6 EON96395.1 - 2.3e-19 69.4 0.0 3.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Asp PF00026.18 EON96397.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic aspartyl protease DUF3433 PF11915.3 EON96398.1 - 0.11 12.6 0.3 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) AA_permease PF00324.16 EON96399.1 - 5.4e-123 410.8 43.5 6.3e-123 410.6 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON96399.1 - 3e-28 98.5 48.5 3.6e-28 98.2 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease WW PF00397.21 EON96400.1 - 2.2e-10 40.2 0.4 4.6e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EON96400.1 - 4.5 7.2 19.8 3.1e+02 1.2 13.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Hydrolase PF00702.21 EON96401.1 - 1.8e-18 67.7 0.0 8.7e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EON96401.1 - 2.2e-15 56.3 0.0 3.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EON96401.1 - 2.1e-12 47.6 0.0 5.6e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON96401.1 - 0.00065 19.6 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EON96401.1 - 0.013 15.0 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EON96402.1 - 1.9e-35 122.2 23.5 1e-28 100.1 1.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96402.1 - 9e-12 44.3 3.2 9e-12 44.3 2.2 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EON96402.1 - 0.014 13.8 22.4 0.0051 15.2 3.2 2.8 2 1 0 2 2 2 0 MFS/sugar transport protein Pkinase PF00069.20 EON96403.1 - 1e-62 211.6 0.0 1.7e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96403.1 - 3e-36 124.8 0.0 5.3e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EON96403.1 - 7.1e-30 102.5 20.8 5.9e-17 61.1 4.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EON96403.1 - 9.8e-21 73.2 28.3 5.9e-12 45.1 6.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EON96403.1 - 5.4e-14 52.4 2.2 5.4e-14 52.4 1.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EON96403.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sin_N PF04801.8 EON96404.1 - 1.3e-07 30.8 0.4 3.8e-07 29.3 0.0 1.9 2 1 0 2 2 2 1 Sin-like protein conserved region TPR_11 PF13414.1 EON96405.1 - 1.7e-11 43.6 4.7 4.2e-10 39.1 0.1 2.8 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EON96405.1 - 6.9e-07 28.6 8.2 0.0027 17.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EON96405.1 - 3.4e-05 23.4 6.7 0.44 10.5 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EON96405.1 - 0.00013 22.2 2.3 0.00043 20.5 1.4 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EON96405.1 - 0.0063 16.6 1.4 0.019 15.1 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EON96405.1 - 0.0068 16.5 1.0 0.036 14.1 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EON96405.1 - 0.11 13.2 2.5 0.31 11.7 1.7 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EON96405.1 - 0.18 12.5 3.0 1.4 9.7 0.7 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat ACBP PF00887.14 EON96406.1 - 5.3e-26 90.0 1.2 6e-26 89.9 0.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1436 PF07262.6 EON96406.1 - 0.054 12.9 0.6 0.12 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Amidinotransf PF02274.12 EON96406.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase WHEP-TRS PF00458.15 EON96406.1 - 5.9 6.6 9.6 0.75 9.5 0.2 3.0 3 0 0 3 3 3 0 WHEP-TRS domain SUR7 PF06687.7 EON96407.1 - 1.2e-25 90.3 10.3 1.4e-25 90.0 7.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EON96407.1 - 0.0075 16.1 3.6 0.0075 16.1 2.5 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 TauD PF02668.11 EON96408.1 - 8.5e-34 117.3 0.0 1.5e-33 116.5 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sensor PF13796.1 EON96409.1 - 0.054 13.0 2.9 0.1 12.1 2.0 1.5 1 1 0 1 1 1 0 Putative sensor Tad PF13400.1 EON96409.1 - 0.11 12.5 4.0 0.18 11.8 2.8 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like TauD PF02668.11 EON96410.1 - 2.9e-15 56.6 0.0 4.2e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lipase_GDSL PF00657.17 EON96412.1 - 1.2e-13 51.4 0.4 1.5e-13 51.1 0.3 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EON96412.1 - 1.3e-11 44.9 0.3 1.7e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EON96412.1 - 2.5e-05 24.1 0.1 3.1e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ALG3 PF05208.8 EON96414.1 - 3.5e-133 444.3 15.9 4.7e-133 443.9 11.0 1.1 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.19 EON96414.1 - 3.1e-20 72.4 0.0 4.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EON96414.1 - 0.00036 19.5 0.0 0.0006 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EON96414.1 - 0.001 19.0 0.1 0.0029 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON96414.1 - 0.0029 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON96414.1 - 0.015 14.3 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EON96414.1 - 0.026 13.0 0.2 0.038 12.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EON96414.1 - 0.033 14.5 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON96414.1 - 0.089 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EON96414.1 - 0.14 11.5 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Transp_cyt_pur PF02133.10 EON96415.1 - 7.2e-55 186.2 20.1 8.7e-55 186.0 14.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Acetyltransf_1 PF00583.19 EON96416.1 - 3.8e-07 30.0 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EON96416.1 - 2.3e-06 27.2 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EON96416.1 - 0.0081 16.2 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EON96416.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_2 PF03446.10 EON96417.1 - 1.9e-38 131.8 0.1 2.9e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EON96417.1 - 2.7e-32 111.4 0.2 6e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EON96417.1 - 1.3e-06 28.6 0.1 3.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EON96417.1 - 3.5e-06 26.0 0.0 5.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EON96417.1 - 1.6e-05 25.3 0.1 5.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EON96417.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EON96417.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EON96417.1 - 0.021 14.4 0.3 0.07 12.7 0.2 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EON96417.1 - 0.03 14.6 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M20 PF01546.23 EON96418.1 - 2.8e-26 92.1 0.0 4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON96418.1 - 5.4e-12 45.4 0.0 1.8e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EON96418.1 - 0.0021 17.8 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Reticulon PF02453.12 EON96419.1 - 1.9e-39 134.9 3.1 2.9e-39 134.3 2.2 1.2 1 0 0 1 1 1 1 Reticulon Wzy_C PF04932.10 EON96419.1 - 4.4 7.0 6.1 4.3 7.0 0.0 2.5 2 1 1 3 3 3 0 O-Antigen ligase Rho_GDI PF02115.12 EON96420.1 - 1.6e-53 181.0 0.4 3.5e-53 180.0 0.0 1.6 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor Transp_cyt_pur PF02133.10 EON96421.1 - 7.5e-23 80.7 35.1 1.8e-22 79.5 24.3 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RabGAP-TBC PF00566.13 EON96422.1 - 4.6e-49 166.7 0.0 1.2e-48 165.4 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Inositol_P PF00459.20 EON96424.1 - 4.5e-63 213.0 0.0 5.3e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DIOX_N PF14226.1 EON96425.1 - 2.4e-18 66.7 0.0 6e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EON96425.1 - 8.1e-16 58.1 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EON96426.1 - 3.1e-89 299.5 35.6 4.3e-89 299.0 24.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aminotran_1_2 PF00155.16 EON96427.1 - 1.4e-62 211.8 0.0 1.7e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EON96427.1 - 0.099 10.9 0.0 0.16 10.1 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Acyl-CoA_dh_1 PF00441.19 EON96428.1 - 3.1e-38 131.2 3.9 4.8e-38 130.6 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EON96428.1 - 2.2e-28 99.1 0.4 6.1e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EON96428.1 - 2.5e-17 63.3 1.6 4e-17 62.7 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON96428.1 - 1.1e-16 60.0 0.0 2.2e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 EON96428.1 - 0.00063 19.2 0.4 0.003 16.9 0.3 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PD40 PF07676.7 EON96429.1 - 0.057 13.1 1.7 21 4.9 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.16 EON96429.1 - 0.063 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 NHL repeat Nup160 PF11715.3 EON96429.1 - 0.089 10.9 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Transp_cyt_pur PF02133.10 EON96430.1 - 1.5e-60 204.9 19.3 1.9e-60 204.7 13.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 EON96431.1 - 1.2e-26 93.2 23.2 1.9e-26 92.6 16.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96431.1 - 5e-05 22.0 21.1 0.00049 18.7 14.7 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter Peptidase_S8 PF00082.17 EON96432.1 - 1.1e-48 165.8 8.8 1.5e-48 165.3 6.1 1.2 1 0 0 1 1 1 1 Subtilase family GMC_oxred_N PF00732.14 EON96433.1 - 1.1e-29 103.5 0.1 1.1e-25 90.3 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EON96433.1 - 9.2e-29 100.5 0.0 1.6e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON96433.1 - 0.0015 17.4 0.1 0.012 14.4 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EON96433.1 - 0.0022 17.9 0.0 0.0087 16.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EON96433.1 - 0.015 14.1 2.1 1.9 7.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON96433.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EON96433.1 - 0.031 14.1 3.3 0.072 12.9 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON96433.1 - 0.037 14.0 0.1 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON96433.1 - 0.13 11.2 0.4 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DUF946 PF06101.6 EON96434.1 - 3.7e-08 31.8 1.3 0.00015 19.9 0.1 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) PC_rep PF01851.17 EON96435.1 - 5.2e-12 45.2 0.2 0.00087 19.3 0.0 4.7 4 0 0 4 4 4 3 Proteasome/cyclosome repeat CsiD PF08943.5 EON96435.1 - 0.0094 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 CsiD RGS PF00615.14 EON96436.1 - 1.8e-08 34.4 0.0 3.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain peroxidase PF00141.18 EON96437.1 - 1.5e-88 296.1 0.0 2.6e-49 167.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.11 EON96438.1 - 2e-32 112.2 25.3 2e-32 112.2 17.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 EON96438.1 - 0.0072 15.5 0.4 0.014 14.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) MFS_1_like PF12832.2 EON96438.1 - 0.027 14.2 0.0 0.027 14.2 0.0 2.8 3 0 0 3 3 3 0 MFS_1 like family Bax1-I PF01027.15 EON96438.1 - 3.2 7.3 18.3 0.14 11.7 2.0 2.9 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 EON96439.1 - 4.8e-22 78.1 31.6 8.6e-18 64.1 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.1 EON96439.1 - 0.015 14.9 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly NfeD PF01957.13 EON96439.1 - 4.7 7.3 8.0 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Bax1-I PF01027.15 EON96439.1 - 8.3 5.9 22.2 0.023 14.2 6.2 2.7 2 1 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 zf-HC2 PF13490.1 EON96440.1 - 0.043 13.7 0.3 0.043 13.7 0.2 2.1 2 0 0 2 2 2 0 Putative zinc-finger Amidohydro_4 PF13147.1 EON96441.1 - 3.2e-22 79.8 8.8 1e-21 78.2 6.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EON96441.1 - 2.7e-14 53.5 0.6 2.2e-10 40.7 0.3 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EON96441.1 - 2.4e-10 40.0 0.3 2.4e-10 40.0 0.2 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EON96441.1 - 1.5e-09 37.5 0.6 1.4e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 EON96442.1 - 2.5e-32 111.9 42.0 3.1e-31 108.3 26.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HemY_N PF07219.8 EON96442.1 - 1.3 8.6 3.8 0.52 9.8 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Clathrin PF00637.15 EON96443.1 - 3.8e-21 75.1 1.3 2.2e-19 69.4 0.4 3.3 3 2 1 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.27 EON96443.1 - 4.7e-06 26.2 0.1 0.018 14.9 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EON96443.1 - 0.0006 19.5 0.4 0.0014 18.4 0.3 1.7 1 0 0 1 1 1 1 Ring finger domain CENP-B_dimeris PF09026.5 EON96443.1 - 0.0025 18.0 5.3 0.0025 18.0 3.7 3.0 3 0 0 3 3 3 1 Centromere protein B dimerisation domain Vps39_1 PF10366.4 EON96443.1 - 0.0028 17.6 0.1 0.097 12.6 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 EON96443.1 - 0.059 13.1 1.7 0.15 11.8 1.2 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Coatomer_WDAD PF04053.9 EON96443.1 - 0.18 10.5 0.2 11 4.7 0.0 2.5 3 0 0 3 3 3 0 Coatomer WD associated region VID27 PF08553.5 EON96443.1 - 2.4 6.2 5.4 6.3 4.8 3.7 1.6 1 0 0 1 1 1 0 VID27 cytoplasmic protein XS PF03468.9 EON96444.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 XS domain BRO1 PF03097.13 EON96445.1 - 0.0016 17.2 0.0 0.0021 16.8 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain IDO PF01231.13 EON96446.1 - 2.4e-111 372.1 0.0 2.7e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DXPR_C PF13288.1 EON96446.1 - 0.099 12.6 0.0 8.8 6.3 0.0 2.2 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain Aminotran_5 PF00266.14 EON96447.1 - 1.9e-07 30.1 0.0 1.2e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EON96447.1 - 0.029 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AAA PF00004.24 EON96448.1 - 4.7e-45 153.0 0.0 1.6e-44 151.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EON96448.1 - 0.00037 20.5 3.9 0.029 14.3 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EON96448.1 - 0.0017 17.4 0.0 0.004 16.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EON96448.1 - 0.0035 16.7 0.2 0.76 9.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EON96448.1 - 0.0078 17.0 0.1 0.037 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EON96448.1 - 0.015 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EON96448.1 - 0.025 14.7 0.1 0.41 10.7 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EON96448.1 - 0.028 14.2 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EON96448.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EON96448.1 - 0.063 13.0 0.0 0.38 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EON96448.1 - 0.1 11.7 0.1 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EON96448.1 - 0.11 12.1 0.1 6.9 6.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain RRS1 PF04939.7 EON96449.1 - 5.6e-56 188.5 3.2 6.6e-56 188.3 2.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) IBR PF01485.16 EON96450.1 - 0.0027 17.5 11.9 0.0027 17.5 8.3 2.3 3 0 0 3 3 3 1 IBR domain RhoGAP PF00620.22 EON96451.1 - 3.7e-27 94.8 0.0 6.7e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Aminotran_1_2 PF00155.16 EON96452.1 - 2e-36 125.7 0.0 2.2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 EON96453.1 - 9.8e-84 281.5 14.3 1.1e-83 281.3 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96453.1 - 3.6e-30 104.8 40.9 2e-28 99.1 13.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON96453.1 - 2.8e-05 22.5 0.4 2.8e-05 22.5 0.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EON96453.1 - 0.00017 20.1 2.6 0.00017 20.1 1.8 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein MutS_V PF00488.16 EON96454.1 - 1.4e-78 263.5 0.0 4.2e-78 262.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EON96454.1 - 5.6e-38 130.7 1.1 9.7e-38 129.9 0.5 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EON96454.1 - 7e-28 96.9 0.0 1.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EON96454.1 - 4.9e-11 42.8 0.0 1.4e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EON96454.1 - 4e-07 30.1 0.0 1.9e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV MCM PF00493.18 EON96455.1 - 5.2e-134 446.2 0.9 6.9e-134 445.8 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EON96455.1 - 2.2e-25 89.4 0.2 7.3e-25 87.8 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EON96455.1 - 1.5e-07 30.7 0.0 1.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EON96455.1 - 1.5e-06 27.9 0.1 1.7e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EON96455.1 - 0.0031 17.8 1.4 0.014 15.8 0.3 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EON96455.1 - 0.019 14.5 0.0 0.066 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Alg6_Alg8 PF03155.10 EON96457.1 - 5.5e-93 312.3 15.9 9.7e-84 281.8 9.3 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MFS_1 PF07690.11 EON96458.1 - 5.8e-35 120.6 48.1 3e-27 95.2 15.1 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96459.1 - 1.2e-45 155.9 26.3 1.8e-32 112.5 8.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON96459.1 - 1.7e-16 59.9 27.1 1.4e-10 40.4 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2670 PF10875.3 EON96459.1 - 0.038 14.0 0.7 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Prenyltrans PF00432.16 EON96460.1 - 3.5e-59 195.9 3.8 9.1e-12 44.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EON96460.1 - 1.1e-37 128.9 0.0 2.3e-14 53.7 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EON96460.1 - 2.2e-12 46.9 0.0 0.00014 21.8 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like DAP3 PF10236.4 EON96461.1 - 4e-90 301.8 0.0 5.4e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EON96461.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAA_hydrolase PF01557.13 EON96462.1 - 3.8e-57 193.2 0.0 5.9e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GatB_N PF02934.10 EON96463.1 - 6.6e-99 330.4 0.0 1e-98 329.7 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EON96463.1 - 5.3e-10 39.1 0.0 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 GatB domain Lactamase_B PF00753.22 EON96465.1 - 1.5e-08 34.5 0.1 2e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EON96465.1 - 0.00026 20.5 0.1 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.2 EON96466.1 - 1.2e-22 80.9 0.0 1.4e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96466.1 - 7.8e-17 61.6 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON96466.1 - 1.1e-10 41.4 0.1 1.4e-09 37.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EON96466.1 - 8.9e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 EON96466.1 - 0.0056 16.1 0.0 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 EON96466.1 - 0.047 13.9 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EON96466.1 - 0.16 11.5 0.0 0.48 9.9 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein DUF716 PF04819.7 EON96468.1 - 0.011 15.2 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) MFS_1 PF07690.11 EON96469.1 - 2.9e-35 121.6 25.7 2.9e-35 121.6 17.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3139 PF11337.3 EON96469.1 - 1.4 9.2 6.6 11 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) CRPA PF05745.6 EON96469.1 - 3.6 7.3 7.4 0.27 11.0 0.9 2.2 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Aldedh PF00171.17 EON96470.1 - 5.4e-180 598.6 0.4 6.2e-180 598.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EON96470.1 - 0.024 13.8 0.1 2.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Peptidase_S8 PF00082.17 EON96471.1 - 2.2e-13 50.0 0.1 3.3e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EON96471.1 - 1.6e-06 27.7 0.0 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EON96471.1 - 1e-05 25.8 0.0 6.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Transp_cyt_pur PF02133.10 EON96472.1 - 4.4e-30 104.6 37.4 7e-30 103.9 25.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.17 EON96473.1 - 4.9e-39 134.1 0.5 1.7e-26 92.8 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_31 PF01055.21 EON96474.1 - 3e-82 276.8 0.1 3.7e-82 276.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EON96474.1 - 5.3e-14 51.8 0.0 1.8e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like ADH_zinc_N PF00107.21 EON96475.1 - 8.8e-14 51.1 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON96475.1 - 4.5e-11 42.4 4.9 9.3e-11 41.4 3.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EON96475.1 - 6.2e-05 22.2 0.0 9.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EON96475.1 - 0.016 15.0 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EON96475.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Terpene_synth_C PF03936.11 EON96476.1 - 7.6e-11 41.7 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank_2 PF12796.2 EON96479.1 - 4.8e-17 62.0 0.0 1.9e-10 40.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EON96479.1 - 5.9e-11 42.5 0.1 4.2e-07 30.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EON96479.1 - 5.5e-10 38.5 0.1 0.0015 18.2 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EON96479.1 - 3.2e-07 30.3 0.1 0.00014 21.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON96479.1 - 2.2e-05 24.2 0.0 0.43 10.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat MutS_III PF05192.13 EON96479.1 - 0.00096 18.9 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 MutS domain III zf-AD PF07776.10 EON96479.1 - 0.0015 18.4 0.1 0.0037 17.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) F-box PF00646.28 EON96480.1 - 2.1e-07 30.3 0.0 3.1e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EON96480.1 - 3.3e-05 23.5 0.2 3.3e-05 23.5 0.1 2.9 3 0 0 3 3 3 1 F-box-like PRANC PF09372.5 EON96480.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Sugar_tr PF00083.19 EON96481.1 - 2.1e-73 247.4 28.7 3.6e-73 246.6 19.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96481.1 - 2.8e-21 75.6 23.2 1.4e-20 73.2 13.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 EON96482.1 - 2.5e-30 105.5 2.5 2.5e-30 105.5 1.8 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EON96482.1 - 4.4e-16 59.4 0.3 9.3e-16 58.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EON96482.1 - 7.8e-15 54.1 0.1 2.2e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EON96482.1 - 2.3e-14 53.7 2.1 2.3e-14 53.7 1.5 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.1 EON96483.1 - 3.2e-31 108.9 0.1 3.7e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON96483.1 - 7.9e-29 100.7 0.1 9.8e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96483.1 - 1.1e-14 54.5 0.1 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 EON96483.1 - 0.013 15.3 0.3 0.033 14.0 0.2 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Hexapep PF00132.19 EON96484.1 - 3.9e-14 51.4 13.1 2.7e-10 39.2 3.6 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EON96484.1 - 1.9e-08 33.6 10.9 1.2e-06 27.9 3.0 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EON96484.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase Transp_cyt_pur PF02133.10 EON96485.1 - 1.2e-59 202.0 12.2 1.4e-59 201.7 8.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_3 PF07859.8 EON96486.1 - 1.5e-46 158.6 0.0 2.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EON96486.1 - 1.2e-07 30.8 0.0 4.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EON96486.1 - 3.4e-06 26.8 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EON96486.1 - 5.7e-06 25.7 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EON96486.1 - 3.9e-05 23.6 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EON96486.1 - 0.01 15.2 0.0 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EON96486.1 - 0.021 14.0 0.0 0.54 9.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family 3-alpha PF03475.9 EON96486.1 - 0.03 14.0 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 3-alpha domain Peptidase_S28 PF05577.7 EON96488.1 - 1.2e-44 152.5 0.9 2.7e-44 151.4 0.6 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 NMT1 PF09084.6 EON96489.1 - 3e-12 46.5 0.0 4.4e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EON96489.1 - 1.3e-05 24.6 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EON96489.1 - 0.00032 20.1 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.7 EON96489.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FMO-like PF00743.14 EON96491.1 - 4.8e-25 87.7 0.0 6.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EON96491.1 - 4.9e-14 52.8 0.0 6.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON96491.1 - 2.9e-10 39.5 0.0 1.4e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EON96491.1 - 6.1e-07 29.3 0.0 4.6e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EON96491.1 - 6.8e-06 26.1 0.0 1.8e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON96491.1 - 9.6e-06 25.5 0.0 3.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EON96491.1 - 0.059 13.4 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EON96491.1 - 0.059 12.4 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EON96491.1 - 0.12 11.4 0.1 2.8 6.8 0.1 2.2 2 1 0 2 2 2 0 FAD binding domain Laminin_II PF06009.7 EON96492.1 - 0.005 16.6 15.1 0.024 14.4 7.1 2.4 1 1 1 2 2 2 1 Laminin Domain II IncA PF04156.9 EON96492.1 - 0.011 15.3 21.2 0.024 14.2 14.7 1.6 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EON96492.1 - 0.041 12.3 14.3 0.063 11.7 9.9 1.3 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.11 EON96492.1 - 0.059 13.2 7.9 0.084 12.7 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apo-CIII PF05778.7 EON96492.1 - 0.063 12.6 0.7 0.87 9.0 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Ribosomal_S2 PF00318.15 EON96492.1 - 0.14 11.3 0.1 0.14 11.3 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S2 GvpL_GvpF PF06386.6 EON96492.1 - 0.15 11.6 17.3 0.23 11.0 12.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF LMBR1 PF04791.11 EON96492.1 - 0.41 9.1 4.2 0.48 8.9 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF972 PF06156.8 EON96492.1 - 0.51 10.6 17.5 3.2 8.1 6.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FH2 PF02181.18 EON96492.1 - 0.56 9.0 13.6 0.69 8.7 6.0 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain CALCOCO1 PF07888.6 EON96492.1 - 0.93 7.6 20.9 1.3 7.1 14.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 EON96492.1 - 1.6 8.5 30.5 0.11 12.2 9.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Birna_RdRp PF04197.7 EON96492.1 - 1.9 6.3 10.8 2.5 6.0 7.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF572 PF04502.8 EON96492.1 - 2.2 7.4 22.2 2.9 7.0 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cauli_AT PF03233.8 EON96492.1 - 2.2 7.9 12.7 1.7 8.3 4.5 2.5 2 1 0 2 2 2 0 Aphid transmission protein FUSC PF04632.7 EON96492.1 - 2.3 6.5 4.3 3.9 5.7 3.0 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 EON96492.1 - 9.5 3.9 13.2 16 3.1 9.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ToxN_toxin PF13958.1 EON96493.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system PCI PF01399.22 EON96494.1 - 1.9e-11 44.1 0.0 1.8e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EON96494.1 - 0.001 18.5 0.1 0.001 18.5 0.1 2.0 2 1 1 3 3 3 1 26S proteasome subunit RPN7 Laminin_G_2 PF02210.19 EON96494.1 - 0.15 12.1 0.1 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain TPR_12 PF13424.1 EON96495.1 - 8e-17 60.9 8.7 1.2e-06 28.3 1.3 7.1 5 1 2 7 7 7 4 Tetratricopeptide repeat AAA_16 PF13191.1 EON96495.1 - 4.3e-09 36.6 0.0 2.1e-08 34.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EON96495.1 - 1.1e-05 25.1 0.1 0.00012 21.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EON96495.1 - 4.2e-05 23.6 0.3 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.1 EON96495.1 - 0.00024 21.4 0.2 6.6 7.6 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EON96495.1 - 0.0012 18.7 8.5 0.054 13.4 0.2 6.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON96495.1 - 0.95 9.4 5.5 25 4.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat eIF-3_zeta PF05091.7 EON96496.1 - 1.6e-202 673.7 0.0 1.9e-202 673.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EON96496.1 - 0.013 14.9 0.1 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF569) Proteasome PF00227.21 EON96498.1 - 7.5e-26 90.5 0.0 1.2e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 Proteasome subunit MVIN PF03023.9 EON96498.1 - 0.13 10.6 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 MviN-like protein TRI12 PF06609.8 EON96499.1 - 1.4e-23 83.0 4.8 1.6e-23 82.7 3.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON96499.1 - 0.00017 20.4 15.9 0.00017 20.4 11.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.1 EON96499.1 - 1.1 8.9 4.7 1.2 8.8 0.1 2.8 2 1 1 3 3 3 0 Cytochrome oxidase c assembly adh_short PF00106.20 EON96500.1 - 1.4e-22 80.3 0.0 3.7e-22 79.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96500.1 - 2.2e-11 43.9 0.0 7e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96500.1 - 4.7e-08 32.9 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON96500.1 - 0.00051 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EON96500.1 - 0.015 14.9 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 EON96500.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 EON96500.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_26 PF13659.1 EON96500.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain YjeF_N PF03853.10 EON96500.1 - 0.047 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Methyltransf_11 PF08241.7 EON96500.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EON96500.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AAA_31 PF13614.1 EON96500.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain HSCB_C PF07743.8 EON96501.1 - 9.3e-18 64.4 6.8 9.3e-18 64.4 4.7 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EON96501.1 - 2e-07 30.6 0.0 4.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain FBPase PF00316.15 EON96501.1 - 0.057 12.2 0.1 0.078 11.7 0.1 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase NUDIX PF00293.23 EON96502.1 - 6.3e-16 58.2 0.2 3.3e-15 55.9 0.0 2.1 1 1 2 3 3 3 1 NUDIX domain DUF3129 PF11327.3 EON96503.1 - 1.2e-50 171.9 11.2 1.7e-50 171.3 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) HemeBinding_Shp PF11545.3 EON96503.1 - 0.038 13.8 1.1 0.042 13.6 0.1 1.7 2 0 0 2 2 2 0 Cell surface heme-binding protein Shp MFS_1 PF07690.11 EON96504.1 - 0.00013 20.7 0.2 0.00013 20.7 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96505.1 - 1e-23 83.6 31.2 8.1e-14 51.0 8.2 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Helicase_C PF00271.26 EON96506.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Apolipoprotein PF01442.13 EON96507.1 - 0.0008 18.9 11.6 1.2 8.6 5.6 3.7 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain FliJ PF02050.11 EON96507.1 - 0.0032 17.5 1.8 0.0032 17.5 1.3 4.2 3 1 0 4 4 4 1 Flagellar FliJ protein ING PF12998.2 EON96507.1 - 0.11 12.7 10.5 6.3 7.1 0.1 3.9 3 2 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF883 PF05957.8 EON96507.1 - 0.82 10.1 18.8 15 6.0 0.0 5.8 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) Acyl-CoA_dh_C PF12806.2 EON96507.1 - 3.7 7.4 9.4 12 5.8 0.8 3.8 3 1 1 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like ATC_hydrolase PF14196.1 EON96507.1 - 6.3 7.1 14.7 3.6 7.9 0.1 3.8 4 0 0 4 4 4 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF4404 PF14357.1 EON96507.1 - 8.6 6.8 11.8 32 5.0 0.0 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) DUF3712 PF12505.3 EON96508.1 - 1.5e-28 99.3 6.4 8.1e-28 96.9 2.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF805 PF05656.9 EON96508.1 - 0.01 15.6 0.7 0.019 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3328 PF11807.3 EON96508.1 - 0.02 14.5 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3753 PF12575.3 EON96508.1 - 0.037 13.8 1.4 0.078 12.7 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF2393 PF09624.5 EON96508.1 - 0.069 12.6 1.4 0.11 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) AAA PF00004.24 EON96509.1 - 5.2e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EON96509.1 - 5.3e-08 33.0 0.0 6.4e-06 26.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EON96509.1 - 1.4e-06 28.3 0.0 7.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EON96509.1 - 2e-06 27.5 0.1 3.7e-05 23.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EON96509.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EON96509.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EON96509.1 - 0.00023 20.2 0.0 0.00067 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EON96509.1 - 0.00032 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EON96509.1 - 0.00055 20.7 0.7 0.002 18.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EON96509.1 - 0.001 19.3 0.3 0.0081 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EON96509.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EON96509.1 - 0.0016 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EON96509.1 - 0.0018 18.1 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EON96509.1 - 0.0025 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EON96509.1 - 0.0036 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EON96509.1 - 0.0049 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EON96509.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EON96509.1 - 0.0075 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EON96509.1 - 0.0083 15.5 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EON96509.1 - 0.0098 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) eIF-1a PF01176.14 EON96509.1 - 0.015 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF4200 PF13863.1 EON96509.1 - 0.017 15.0 1.3 0.017 15.0 0.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.1 EON96509.1 - 0.02 14.4 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EON96509.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EON96509.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 EON96509.1 - 0.027 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EON96509.1 - 0.03 13.4 0.6 0.12 11.4 0.0 2.3 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 EON96509.1 - 0.03 14.0 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 EON96509.1 - 0.031 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EON96509.1 - 0.037 13.6 0.2 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EON96509.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EON96509.1 - 0.048 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EON96509.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EON96509.1 - 0.087 12.1 0.0 1.4 8.2 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase Parvo_NS1 PF01057.12 EON96509.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EON96509.1 - 0.15 12.3 3.4 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EON96510.1 - 5.7e-71 239.4 23.2 6.5e-71 239.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96510.1 - 1.1e-08 34.1 24.6 1.1e-08 34.1 17.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HATPase_c_2 PF13581.1 EON96510.1 - 0.017 14.9 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Dyp_perox PF04261.7 EON96511.1 - 6.8e-92 307.5 0.0 7.7e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family p450 PF00067.17 EON96512.1 - 2.5e-68 230.7 0.0 3.2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EON96513.1 - 7.3e-16 57.8 51.8 4.3e-08 32.2 13.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON96513.1 - 1.4e-08 33.4 22.4 2.2e-08 32.7 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4014 PF13198.1 EON96513.1 - 0.3 11.5 1.5 53 4.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) Sugar_tr PF00083.19 EON96513.1 - 0.42 9.1 29.6 0.014 13.9 7.7 3.3 2 1 1 3 3 3 0 Sugar (and other) transporter SIS PF01380.17 EON96514.1 - 4.2e-56 188.1 0.1 7e-30 103.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EON96514.1 - 2.7e-27 95.4 0.0 7.8e-19 67.5 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EON96514.1 - 1.8e-19 69.9 0.0 4.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EON96514.1 - 3.1e-11 43.1 0.0 6.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EON96514.1 - 9.8e-07 27.7 0.0 1.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EON96514.1 - 0.026 14.2 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 SIS domain Lipase_GDSL_2 PF13472.1 EON96515.1 - 1.1e-20 74.4 0.0 1.4e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EON96515.1 - 8.5e-08 32.3 0.2 4.9e-07 29.8 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_6 PF12697.2 EON96517.1 - 1.2e-29 103.8 0.1 1.7e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96517.1 - 5.2e-12 45.7 0.0 5.9e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96517.1 - 1.3e-08 34.6 0.2 3.1e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON96517.1 - 0.01 15.0 0.0 0.028 13.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.7 EON96517.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.3 EON96517.1 - 0.035 13.4 0.0 0.086 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EON96517.1 - 0.037 14.2 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 EON96517.1 - 0.073 12.7 0.1 0.76 9.4 0.0 2.4 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal FMN_dh PF01070.13 EON96518.1 - 6.7e-104 347.5 0.0 8.9e-104 347.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EON96518.1 - 6.7e-21 73.8 0.0 1.6e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EON96518.1 - 2.4e-06 26.7 0.1 3.6e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EON96518.1 - 3.2e-05 23.0 0.0 0.00018 20.4 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EON96518.1 - 0.011 15.0 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 EON96518.1 - 0.03 13.4 0.3 0.05 12.7 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ATP11 PF06644.6 EON96518.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein Ribul_P_3_epim PF00834.14 EON96518.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.16 EON96518.1 - 0.16 10.8 0.1 1.1 8.0 0.0 2.0 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase Bac_luciferase PF00296.15 EON96519.1 - 4.4e-30 104.8 0.0 1.2e-28 100.1 0.0 2.1 1 1 1 2 2 2 2 Luciferase-like monooxygenase FAD_binding_4 PF01565.18 EON96520.1 - 6.1e-18 64.6 7.8 2.2e-17 62.8 2.5 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 EON96520.1 - 5.9e-13 48.5 0.2 2.8e-12 46.3 0.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like DUF1993 PF09351.5 EON96522.1 - 1.4e-27 96.5 0.2 1.6e-27 96.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MecA PF05389.7 EON96522.1 - 0.034 13.6 0.2 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) SNF2_assoc PF08455.5 EON96522.1 - 0.053 12.0 0.1 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated MFS_1 PF07690.11 EON96523.1 - 2.3e-26 92.3 26.1 2.3e-26 92.3 18.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96523.1 - 0.00039 19.1 38.3 0.0071 14.9 25.4 3.3 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2985 PF11204.3 EON96525.1 - 2e-28 97.9 5.1 1e-27 95.6 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Neur_chan_memb PF02932.11 EON96525.1 - 0.0052 16.7 1.3 0.31 10.8 0.0 2.7 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DHDPS PF00701.17 EON96526.1 - 1.9e-42 144.8 0.0 2.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Transp_cyt_pur PF02133.10 EON96527.1 - 1.2e-11 43.8 22.1 3.8e-08 32.3 7.8 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SWIB PF02201.13 EON96528.1 - 1.3e-21 76.0 1.0 1.5e-20 72.6 0.3 2.5 2 1 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EON96528.1 - 5.2e-14 51.7 0.7 8.8e-14 51.0 0.2 1.7 2 0 0 2 2 2 1 DEK C terminal domain DUF4407 PF14362.1 EON96528.1 - 0.4 9.5 4.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Evr1_Alr PF04777.8 EON96529.1 - 1.1e-26 92.5 0.1 1.7e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EON96529.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Proteasome PF00227.21 EON96530.1 - 1.6e-48 164.5 0.2 1.8e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 EON96531.1 - 1.5e-45 155.4 0.0 2.5e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EON96531.1 - 1.6e-45 154.0 0.0 3.1e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EON96531.1 - 5.5e-22 78.0 0.0 8.1e-21 74.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EON96531.1 - 6.5e-06 25.7 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 EON96531.1 - 1.2e-05 24.6 0.2 0.029 13.9 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat APH PF01636.18 EON96531.1 - 0.0021 17.8 0.1 0.0068 16.1 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EON96531.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Neur_chan_memb PF02932.11 EON96531.1 - 0.029 14.2 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YrbL-PhoP_reg PF10707.4 EON96531.1 - 0.055 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FRG2 PF15315.1 EON96531.1 - 0.1 12.5 6.4 0.24 11.3 4.4 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 GMC_oxred_N PF00732.14 EON96532.1 - 5.5e-60 203.0 0.0 7.8e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON96532.1 - 1.6e-30 106.2 0.0 2.7e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EON96532.1 - 1.9e-06 27.0 0.4 0.0024 16.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON96532.1 - 7.5e-05 22.6 0.6 0.00024 21.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EON96532.1 - 0.00027 19.9 0.6 0.00059 18.8 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EON96532.1 - 0.00037 19.4 1.4 0.0018 17.2 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EON96532.1 - 0.0015 18.6 0.6 0.27 11.2 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON96532.1 - 0.048 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EON96532.1 - 0.075 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding C2 PF00168.25 EON96533.1 - 6e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain OPT PF03169.10 EON96534.1 - 3.3e-14 52.2 2.5 4.1e-14 51.9 1.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 EON96535.1 - 2.1e-13 49.7 30.9 1.1e-09 37.4 14.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 EON96536.1 - 1.4e-132 442.4 36.4 1.6e-132 442.2 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON96536.1 - 7.7e-35 120.2 38.6 1e-34 119.8 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EON96537.1 - 8.7e-12 45.2 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96537.1 - 1.2e-05 25.2 0.0 1.4e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EON96537.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.19 EON96538.1 - 5.1e-85 285.7 32.9 5.8e-85 285.5 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96538.1 - 2.3e-30 105.5 59.2 1.7e-28 99.3 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EON96538.1 - 0.037 13.5 1.5 0.5 9.8 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) SepZ PF06066.6 EON96538.1 - 1.6 8.7 8.3 2.3 8.2 3.1 2.8 2 1 1 3 3 3 0 SepZ UBN2 PF14223.1 EON96540.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cyt-b5 PF00173.23 EON96541.1 - 2e-16 59.5 0.0 5.3e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EON96541.1 - 6.3e-15 55.3 12.2 6.3e-15 55.3 8.4 1.8 1 1 1 2 2 2 1 Fatty acid desaturase TAP42 PF04177.7 EON96542.1 - 3e-107 358.5 0.0 3.4e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family HAT PF02184.11 EON96542.1 - 0.013 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat DUF1399 PF07173.7 EON96542.1 - 0.069 13.4 0.4 0.43 10.8 0.1 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 EON96543.1 - 1.6e-21 76.3 0.7 2.1e-21 76.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain T4_deiodinase PF00837.12 EON96543.1 - 0.051 12.5 0.1 0.16 10.9 0.0 1.8 1 1 0 1 1 1 0 Iodothyronine deiodinase GTP_EFTU PF00009.22 EON96544.1 - 8.2e-33 113.4 0.0 2.9e-32 111.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EON96544.1 - 2.4e-18 66.0 0.0 5.8e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EON96544.1 - 4.9e-09 36.1 8.6 5.7e-08 32.7 0.1 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EON96544.1 - 5.8e-06 26.2 0.0 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EON96544.1 - 0.0016 18.0 0.0 0.0046 16.5 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EON96544.1 - 0.0066 16.9 0.0 0.039 14.4 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein TrkA_C PF02080.16 EON96544.1 - 0.0081 15.7 1.1 5 6.7 0.0 3.3 3 0 0 3 3 3 1 TrkA-C domain AAA_16 PF13191.1 EON96544.1 - 0.098 12.6 0.0 0.098 12.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain EMP70 PF02990.11 EON96545.1 - 7.3e-165 549.3 1.6 1.9e-164 547.9 1.1 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 MecA_N PF05223.6 EON96545.1 - 0.015 15.3 0.1 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain GDI PF00996.13 EON96547.1 - 3e-180 599.2 0.0 3.7e-180 598.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor eIF-5a PF01287.15 EON96548.1 - 2.6e-26 91.3 2.0 3.7e-26 90.8 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EON96548.1 - 0.0044 16.8 0.5 0.014 15.1 0.0 2.0 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EON96548.1 - 0.0089 15.7 0.3 0.02 14.6 0.2 1.6 1 0 0 1 1 1 1 KOW motif Response_reg PF00072.19 EON96548.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain NCA2 PF08637.5 EON96549.1 - 5.4e-87 291.3 0.0 7e-87 290.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EON96549.1 - 0.15 10.8 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Ras PF00071.17 EON96550.1 - 1.5e-64 216.2 0.0 1.8e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON96550.1 - 1.3e-19 70.8 0.0 2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON96550.1 - 4.3e-13 48.8 0.0 5.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EON96550.1 - 2.5e-06 27.0 0.1 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EON96550.1 - 1e-05 24.7 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EON96550.1 - 0.0044 16.9 0.0 0.0066 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EON96550.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MCM PF00493.18 EON96550.1 - 0.046 12.5 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 EON96550.1 - 0.046 12.9 0.0 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EON96550.1 - 0.054 13.6 0.0 6.1 7.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EON96550.1 - 0.056 12.7 0.0 0.27 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EON96550.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EON96550.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain DASH_Dad4 PF08650.5 EON96551.1 - 2.8e-29 100.8 6.1 3.1e-29 100.6 4.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EON96551.1 - 0.11 12.1 3.8 0.14 11.8 2.7 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Eaf7 PF07904.8 EON96552.1 - 3.4e-26 91.0 0.0 3.4e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DASH_Ask1 PF08655.5 EON96552.1 - 1.7e-23 82.2 0.1 3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Nop14 PF04147.7 EON96552.1 - 0.16 9.8 17.6 0.25 9.2 12.2 1.3 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 EON96552.1 - 0.36 10.2 10.7 0.72 9.2 7.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 EON96552.1 - 0.76 7.7 11.7 1.2 7.1 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein AUX_IAA PF02309.11 EON96552.1 - 1.9 8.1 10.9 6.6 6.4 7.5 2.0 1 0 0 1 1 1 0 AUX/IAA family SAPS PF04499.10 EON96552.1 - 2.4 6.6 5.6 3.2 6.2 3.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EON96552.1 - 2.9 5.5 8.2 4.1 5.0 5.7 1.1 1 0 0 1 1 1 0 Ycf1 NOA36 PF06524.7 EON96552.1 - 5.5 6.1 10.4 19 4.3 7.0 2.0 2 0 0 2 2 2 0 NOA36 protein Paf1 PF03985.8 EON96552.1 - 9.6 4.8 18.4 16 4.0 12.8 1.3 1 0 0 1 1 1 0 Paf1 MIF4G PF02854.14 EON96553.1 - 5.4e-58 195.8 0.0 5.9e-27 94.4 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EON96553.1 - 4.2e-36 124.2 25.4 4.2e-36 124.2 17.6 3.3 2 1 0 2 2 2 1 Up-frameshift suppressor 2 MMR_HSR1 PF01926.18 EON96554.1 - 7.9e-08 32.2 0.0 9.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sec63 PF02889.11 EON96555.1 - 1.1e-154 514.3 0.0 3.3e-98 328.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EON96555.1 - 3e-40 137.4 0.4 1.8e-27 95.8 0.3 3.6 3 1 1 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EON96555.1 - 1.7e-17 62.9 0.0 5.5e-07 29.3 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EON96555.1 - 1.4e-11 44.6 0.1 3.6e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EON96555.1 - 2e-06 27.4 0.3 0.031 14.0 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_22 PF13401.1 EON96555.1 - 0.0012 18.9 0.3 0.096 12.8 0.1 3.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EON96555.1 - 0.0052 16.2 0.0 11 5.4 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein T2SE PF00437.15 EON96555.1 - 0.03 13.2 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EON96555.1 - 0.056 12.6 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Pribosyltran PF00156.22 EON96557.1 - 5.5e-17 61.6 0.6 9e-17 60.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EON96557.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TatD_DNase PF01026.16 EON96559.1 - 4.9e-30 104.5 0.0 8.2e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase BpuJI_N PF11564.3 EON96559.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Trehalose_PPase PF02358.11 EON96560.1 - 0.11 11.3 0.3 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase Bul1_N PF04425.7 EON96561.1 - 1e-05 24.3 0.2 0.00053 18.6 0.0 2.9 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 EON96561.1 - 2.1e-05 23.8 0.0 5.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EON96561.1 - 4.3e-05 23.3 0.0 0.00039 20.2 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EON96561.1 - 0.00032 20.8 0.5 0.35 10.9 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DUF3251 PF11622.3 EON96561.1 - 0.017 14.5 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Macoilin PF09726.4 EON96561.1 - 7.7 4.6 8.4 0.19 10.0 1.5 1.4 2 0 0 2 2 2 0 Transmembrane protein SNF2_N PF00176.18 EON96563.1 - 1.1e-54 185.2 0.0 1.7e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON96563.1 - 7.6e-12 44.9 0.1 2.1e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EON96563.1 - 2.7e-06 27.0 2.3 5.1e-06 26.1 1.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EON96563.1 - 0.0003 20.3 0.0 0.00073 19.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EON96563.1 - 0.14 12.0 1.9 0.3 10.9 1.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EON96563.1 - 0.48 10.1 4.8 2.2 8.0 3.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PI-PLC-X PF00388.14 EON96564.1 - 7.4e-07 28.6 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CPSF_A PF03178.10 EON96565.1 - 0.018 14.1 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region Yip1 PF04893.12 EON96566.1 - 2.2e-12 46.7 9.8 3.2e-12 46.3 6.8 1.4 1 0 0 1 1 1 1 Yip1 domain REJ PF02010.10 EON96567.1 - 0.2 9.9 0.0 0.27 9.5 0.0 1.1 1 0 0 1 1 1 0 REJ domain Peptidase_C12 PF01088.16 EON96568.1 - 1e-63 214.3 0.0 1.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 cNMP_binding PF00027.24 EON96569.1 - 5e-39 132.0 0.1 2.2e-18 65.8 0.0 5.0 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EON96569.1 - 1.5e-16 60.9 7.7 4.3e-16 59.4 3.3 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase p450 PF00067.17 EON96570.1 - 3.1e-51 174.3 0.0 6.1e-51 173.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.14 EON96571.1 - 3.3e-35 119.5 0.5 6.9e-35 118.4 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EON96571.1 - 9.1e-30 102.9 0.0 1.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EON96571.1 - 4.3e-05 23.2 0.1 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease SE PF08491.5 EON96573.1 - 1.4e-88 296.2 0.0 1.8e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EON96573.1 - 0.097 11.7 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Ribonuclease_3 PF00636.21 EON96574.1 - 6e-45 152.3 1.3 7.4e-22 77.9 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EON96574.1 - 6.7e-27 93.9 0.0 1.4e-11 44.4 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EON96574.1 - 3.1e-24 84.5 1.1 5.1e-22 77.4 0.1 3.5 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 EON96574.1 - 1.3e-12 47.4 0.1 4.1e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON96574.1 - 1.7e-09 37.7 0.2 9.3e-09 35.3 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EON96574.1 - 8.9e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EON96574.1 - 0.00044 20.7 0.7 0.51 10.9 0.0 3.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif AAA_22 PF13401.1 EON96574.1 - 0.0049 17.0 0.0 0.022 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Rhodanese PF00581.15 EON96575.1 - 6.5e-14 52.2 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.12 EON96576.1 - 1.9e-11 43.8 17.3 3.4e-11 42.9 12.0 1.5 1 1 0 1 1 1 1 Yip1 domain DDDD PF10161.4 EON96576.1 - 0.39 10.3 1.8 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Spc97_Spc98 PF04130.8 EON96577.1 - 2.1e-92 310.2 0.0 9.1e-81 271.7 0.0 2.4 1 1 1 2 2 2 2 Spc97 / Spc98 family AAA PF00004.24 EON96578.1 - 9.3e-55 184.4 0.0 5e-41 139.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EON96578.1 - 3.2e-06 27.0 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EON96578.1 - 3.7e-06 27.0 0.8 0.015 15.2 0.0 3.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EON96578.1 - 3.9e-06 27.0 3.9 1.4 9.0 0.1 4.9 3 2 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EON96578.1 - 7.9e-06 25.4 2.0 0.42 9.9 0.0 3.7 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EON96578.1 - 1.1e-05 24.5 0.2 4.3e-05 22.6 0.0 2.1 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EON96578.1 - 2.2e-05 24.4 0.0 0.022 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EON96578.1 - 5.4e-05 22.9 2.1 0.039 13.6 0.0 4.1 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EON96578.1 - 0.00018 21.2 4.6 0.11 12.1 0.6 3.9 3 1 1 4 4 4 1 NACHT domain RNA_helicase PF00910.17 EON96578.1 - 0.00061 19.9 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.1 EON96578.1 - 0.00092 20.0 0.0 2.3 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EON96578.1 - 0.002 18.0 0.0 10 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EON96578.1 - 0.0029 16.7 0.3 0.3 10.2 0.1 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EON96578.1 - 0.0032 17.3 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EON96578.1 - 0.004 16.8 3.4 0.16 11.7 0.1 3.4 3 1 0 3 3 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EON96578.1 - 0.005 16.8 0.0 0.21 11.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EON96578.1 - 0.019 14.5 0.0 8.2 5.8 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EON96578.1 - 0.035 13.6 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EON96578.1 - 0.057 13.0 0.0 2.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 EON96578.1 - 0.086 11.5 0.0 0.19 10.3 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EON96578.1 - 0.086 13.1 0.0 2.8 8.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zip PF02535.17 EON96579.1 - 1.8e-52 178.3 11.4 4e-52 177.1 7.9 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Gly-zipper_YMGG PF13441.1 EON96579.1 - 5.3 6.6 13.9 0.73 9.3 3.8 3.2 3 1 0 3 3 3 0 YMGG-like Gly-zipper PNPOx_C PF10590.4 EON96580.1 - 1e-21 76.1 2.4 3.7e-21 74.3 1.6 2.0 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EON96580.1 - 1.3e-17 63.6 0.0 2.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EON96580.1 - 0.0019 18.5 0.1 0.0037 17.5 0.1 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Asp_protease PF09668.5 EON96581.1 - 4.9e-59 197.3 0.1 7.1e-59 196.7 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EON96581.1 - 1.3e-12 48.0 0.2 5.7e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 EON96581.1 - 2.1e-09 36.9 0.1 4.9e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 EON96581.1 - 5.7e-09 35.2 0.2 1.2e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 EON96581.1 - 6.7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EON96581.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EON96581.1 - 4.3e-06 26.5 0.0 1.3e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EON96581.1 - 0.0062 16.0 0.2 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.3 EON96581.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Fungal_trans_2 PF11951.3 EON96582.1 - 0.0038 15.8 0.1 0.0051 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_2 PF00535.21 EON96583.1 - 2.1e-24 86.1 0.0 4.6e-24 85.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EON96583.1 - 6.5e-11 42.4 0.8 1.8e-08 34.4 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Vps52 PF04129.7 EON96584.1 - 4.5e-67 226.7 0.0 5e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family PI3_PI4_kinase PF00454.22 EON96585.1 - 4.3e-40 137.6 0.0 6.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3474 PF11960.3 EON96585.1 - 0.16 12.0 1.6 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) Synaptobrevin PF00957.16 EON96588.1 - 1.2e-31 108.1 0.3 1.6e-31 107.7 0.2 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EON96588.1 - 1.5e-22 78.9 0.0 2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain DEAD PF00270.24 EON96589.1 - 8.5e-26 90.4 0.0 1.5e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EON96589.1 - 4.5e-12 46.3 0.1 1.3e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EON96589.1 - 2e-09 37.1 0.0 6.5e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EON96589.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 DNA replication factor CDT1 like RSS_P20 PF11757.3 EON96589.1 - 0.14 12.3 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like MRP-L47 PF06984.8 EON96590.1 - 1.2e-20 73.1 0.3 1.2e-20 73.1 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) TEX19 PF15553.1 EON96590.1 - 0.15 11.9 4.6 0.12 12.2 2.0 1.7 2 0 0 2 2 2 0 Testis-expressed protein 19 Pyridox_oxase_2 PF12766.2 EON96591.1 - 2.1e-20 72.8 0.0 3.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RabGAP-TBC PF00566.13 EON96592.1 - 4.1e-14 52.5 0.0 5.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ETC_C1_NDUFA5 PF04716.9 EON96593.1 - 1.5e-23 82.0 1.0 5.5e-23 80.2 0.1 2.2 2 0 0 2 2 2 1 ETC complex I subunit conserved region Proteasome PF00227.21 EON96594.1 - 2.9e-57 193.0 0.1 3.6e-57 192.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EON96594.1 - 1e-13 50.2 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EON96594.1 - 0.004 16.8 0.1 0.099 12.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) YL1_C PF08265.6 EON96595.1 - 3.3e-17 61.7 0.1 5.2e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain ubiquitin PF00240.18 EON96596.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EON96596.1 - 3.1e-30 103.5 9.6 4.9e-30 102.8 6.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EON96596.1 - 4.7e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EON96596.1 - 7.3e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EON96596.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EON96596.1 - 0.0082 16.0 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EON96596.1 - 0.013 15.6 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EON96596.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) HSP70 PF00012.15 EON96597.1 - 4e-162 540.2 11.4 4e-162 540.2 7.9 2.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EON96597.1 - 2e-10 39.8 0.0 5.1e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EON96597.1 - 7.8e-05 22.5 0.5 1.5 8.6 0.0 3.7 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 EON96597.1 - 0.058 13.3 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Nol1_Nop2_Fmu PF01189.12 EON96598.1 - 3.3e-29 102.1 0.0 7.2e-19 68.2 0.0 4.2 4 1 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EON96598.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Profilin PF00235.14 EON96599.1 - 1.7e-34 118.4 0.4 2e-34 118.3 0.3 1.0 1 0 0 1 1 1 1 Profilin RD3 PF14473.1 EON96600.1 - 0.0014 18.1 0.4 0.002 17.5 0.3 1.3 1 0 0 1 1 1 1 RD3 protein CENP-N PF05238.8 EON96600.1 - 0.084 11.9 2.1 0.088 11.8 1.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like UPF0542 PF15086.1 EON96600.1 - 2.1 8.0 5.2 2.4 7.9 2.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 Amidohydro_1 PF01979.15 EON96602.1 - 3e-27 96.1 0.8 4.1e-27 95.7 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EON96602.1 - 9.5e-14 52.0 3.0 1.6e-06 28.3 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EON96602.1 - 2.7e-08 33.4 0.0 8.5e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EON96602.1 - 2.2e-06 27.1 2.6 8.5e-05 21.9 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family Pyridoxal_deC PF00282.14 EON96603.1 - 8.4e-71 238.3 0.0 1.1e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.6 EON96603.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Got1 PF04178.7 EON96604.1 - 3.7e-17 62.5 7.8 4.6e-17 62.2 5.4 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EON96604.1 - 1.7 8.3 9.0 1.3 8.7 1.8 2.4 2 0 0 2 2 2 0 YrhK-like protein Synaptobrevin PF00957.16 EON96605.1 - 3.5e-14 52.1 0.5 5.3e-14 51.5 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EON96605.1 - 1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 EON96605.1 - 0.064 13.0 1.2 0.12 12.1 0.5 1.7 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 G-patch PF01585.18 EON96606.1 - 3.3e-08 33.1 0.4 5.5e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 G-patch domain Guanylin PF02058.10 EON96606.1 - 0.005 16.8 0.3 0.005 16.8 0.2 2.0 2 0 0 2 2 2 1 Guanylin precursor SMK-1 PF04802.10 EON96607.1 - 1.5e-80 269.2 9.2 6.1e-80 267.3 1.6 2.3 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 EON96607.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D YqgF PF14639.1 EON96607.1 - 0.25 10.9 1.6 1.9 8.0 0.0 3.2 4 0 0 4 4 4 0 Holliday-junction resolvase-like of SPT6 Chitin_synth_2 PF03142.10 EON96608.1 - 2.5e-18 65.7 1.2 4e-18 65.1 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EON96608.1 - 2.9e-11 43.4 10.0 7.7e-10 38.8 7.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON96608.1 - 1.3e-06 28.3 0.7 7.2e-06 25.9 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_hydro_17 PF00332.13 EON96609.1 - 9.1e-06 24.9 0.4 1.6e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Ran_BP1 PF00638.13 EON96610.1 - 1.4e-12 47.7 5.3 2.4e-06 27.5 0.1 2.9 3 0 0 3 3 3 2 RanBP1 domain NOGCT PF08155.6 EON96611.1 - 1.4e-27 95.1 1.1 2.8e-27 94.1 0.7 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EON96611.1 - 1.1e-26 92.5 0.6 2.8e-26 91.1 0.4 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EON96611.1 - 1.8e-14 53.6 0.0 3.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EON96611.1 - 5.1e-09 35.6 0.0 1e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EON96611.1 - 0.00055 20.4 0.0 0.0035 17.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EON96611.1 - 0.0017 18.2 0.6 1.7 8.4 0.0 3.2 3 0 0 3 3 3 2 Dynamin family Gtr1_RagA PF04670.7 EON96611.1 - 0.0049 16.0 0.5 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EON96611.1 - 0.01 15.7 0.2 0.88 9.5 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 EON96611.1 - 0.11 12.2 0.2 1.6 8.4 0.0 3.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B SUV3_C PF12513.3 EON96612.1 - 1.7e-15 56.2 1.7 3e-15 55.3 1.2 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EON96612.1 - 1.1e-06 28.4 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mo-co_dimer PF03404.11 EON96613.1 - 2.7e-55 185.5 0.4 5.8e-55 184.4 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EON96613.1 - 1.3e-52 177.5 0.0 2.4e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EON96613.1 - 1.2e-28 99.1 0.0 2.1e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EON96613.1 - 5.2e-25 87.0 0.0 1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EON96613.1 - 8.1e-23 81.0 0.0 2e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EON96613.1 - 0.0084 16.0 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Acetyltransf_1 PF00583.19 EON96614.1 - 1.2e-08 34.8 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON96614.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON96614.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EON96614.1 - 0.0026 17.6 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EON96614.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MbtH PF03621.8 EON96614.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 MbtH-like protein YqeY PF09424.5 EON96615.1 - 1.2e-24 86.7 6.3 1.4e-24 86.5 4.4 1.1 1 0 0 1 1 1 1 Yqey-like protein Actin PF00022.14 EON96616.1 - 1.7e-54 184.8 0.0 1.9e-34 118.7 0.0 2.3 2 0 0 2 2 2 2 Actin adh_short PF00106.20 EON96617.1 - 1.8e-12 47.4 1.3 9.3e-12 45.1 0.0 2.5 3 1 1 4 4 4 1 short chain dehydrogenase KR PF08659.5 EON96617.1 - 5.5e-07 29.4 0.3 2.1e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EON96617.1 - 0.0011 18.8 0.0 0.0041 16.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON96617.1 - 0.0023 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ycf1 PF05758.7 EON96617.1 - 0.019 12.6 0.2 0.023 12.4 0.2 1.1 1 0 0 1 1 1 0 Ycf1 Ldh_1_N PF00056.18 EON96617.1 - 0.11 12.2 0.0 17 5.2 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Atg14 PF10186.4 EON96617.1 - 0.93 8.3 10.2 1.4 7.8 7.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GPO PF05929.6 EON96617.1 - 0.96 8.6 7.7 1.4 8.1 5.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SpoVR PF04293.8 EON96617.1 - 6.1 5.1 8.7 9.2 4.5 6.0 1.2 1 0 0 1 1 1 0 SpoVR like protein Spc24 PF08286.6 EON96618.1 - 5.5e-43 145.4 2.9 9.2e-41 138.2 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 IncA PF04156.9 EON96618.1 - 6.2e-05 22.6 4.1 9.6e-05 22.0 2.9 1.3 1 0 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 EON96618.1 - 0.0012 18.0 2.6 0.0015 17.7 1.8 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein MAP65_ASE1 PF03999.7 EON96618.1 - 0.008 14.8 1.8 0.01 14.4 1.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) BRE1 PF08647.6 EON96618.1 - 0.0093 15.9 5.2 0.015 15.2 3.6 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase AAA_27 PF13514.1 EON96618.1 - 0.019 12.6 7.5 0.024 12.3 5.2 1.0 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EON96618.1 - 0.022 12.6 0.6 0.022 12.6 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Streptin-Immun PF11083.3 EON96618.1 - 0.022 14.7 0.7 0.046 13.7 0.3 1.6 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein FlaC_arch PF05377.6 EON96618.1 - 0.024 14.5 1.3 0.34 10.8 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EON96618.1 - 0.031 14.1 3.5 0.13 12.1 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MAD PF05557.8 EON96618.1 - 0.042 11.9 8.5 0.077 11.0 1.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein EAP30 PF04157.11 EON96618.1 - 0.055 12.6 9.7 0.13 11.3 5.6 1.9 1 1 1 2 2 2 0 EAP30/Vps36 family DUF724 PF05266.9 EON96618.1 - 0.055 13.0 4.1 0.1 12.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Scaffolding_pro PF11418.3 EON96618.1 - 0.061 13.6 3.5 0.17 12.1 2.4 1.8 1 1 0 1 1 1 0 Phi29 scaffolding protein MAGSP PF03082.9 EON96618.1 - 0.07 12.5 2.4 0.1 11.9 1.7 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein Nsp1_C PF05064.8 EON96618.1 - 0.081 12.5 5.8 1.9 8.1 0.8 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region GOLGA2L5 PF15070.1 EON96618.1 - 0.088 11.2 7.6 1.5 7.2 3.3 2.0 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Prefoldin_2 PF01920.15 EON96618.1 - 0.095 12.4 6.6 0.4 10.4 0.9 2.3 2 0 0 2 2 2 0 Prefoldin subunit Vps5 PF09325.5 EON96618.1 - 0.18 11.0 7.5 0.38 9.9 5.2 1.6 1 1 0 1 1 1 0 Vps5 C terminal like APG6 PF04111.7 EON96618.1 - 0.18 10.8 5.5 0.27 10.2 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Viral_P18 PF04521.8 EON96618.1 - 0.7 9.3 7.1 0.21 11.0 2.0 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3571 PF12095.3 EON96618.1 - 0.71 10.1 3.7 1.4 9.2 1.3 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3571) XhlA PF10779.4 EON96618.1 - 1 9.2 6.4 4.5 7.2 0.5 2.4 1 1 1 2 2 2 0 Haemolysin XhlA KxDL PF10241.4 EON96618.1 - 1.2 9.1 6.2 0.78 9.6 1.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF4164 PF13747.1 EON96618.1 - 2.3 8.4 10.9 5.8 7.1 7.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.7 EON96618.1 - 2.4 7.9 7.7 1.8 8.4 3.3 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EON96618.1 - 2.5 8.5 7.7 16 5.9 0.1 2.5 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 EON96618.1 - 2.8 7.7 9.7 8.4 6.2 1.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 EON96618.1 - 5.2 7.5 11.6 2.3 8.7 2.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) MbeD_MobD PF04899.7 EON96618.1 - 5.7 6.9 8.9 93 3.0 6.2 2.1 1 1 0 1 1 1 0 MbeD/MobD like Syntaxin-6_N PF09177.6 EON96618.1 - 8.6 6.8 7.5 5.7 7.4 2.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FA_hydroxylase PF04116.8 EON96620.1 - 2.8e-16 59.9 17.4 2.8e-16 59.9 12.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fis1_TPR_C PF14853.1 EON96621.1 - 2.8e-25 87.9 1.8 4.7e-25 87.2 1.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EON96621.1 - 6.3e-17 60.5 0.0 1.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EON96621.1 - 0.0097 15.7 1.5 0.0097 15.7 1.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON96621.1 - 0.029 15.0 0.3 0.053 14.2 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Podoplanin PF05808.6 EON96621.1 - 0.52 9.8 2.0 0.74 9.3 1.4 1.2 1 0 0 1 1 1 0 Podoplanin zf-H2C2_2 PF13465.1 EON96622.1 - 4.2e-07 29.9 11.1 5.4e-06 26.4 0.8 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EON96622.1 - 7.7e-06 25.8 14.2 0.00065 19.8 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EON96622.1 - 0.001 19.1 4.7 0.0018 18.3 3.3 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EON96622.1 - 0.0044 17.2 16.8 0.022 15.0 4.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EON96622.1 - 0.33 10.7 1.7 0.59 9.9 1.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EON96622.1 - 0.76 9.5 8.0 0.6 9.9 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EON96622.1 - 1.4 9.1 7.0 3.5 7.8 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding EIF_2_alpha PF07541.7 EON96623.1 - 1.1e-39 134.6 0.0 2.4e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EON96623.1 - 1.2e-11 44.5 0.4 2.5e-11 43.4 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Stathmin PF00836.14 EON96623.1 - 0.011 15.4 1.2 0.048 13.2 0.2 2.1 2 0 0 2 2 2 0 Stathmin family Ribonuclease_T2 PF00445.13 EON96624.1 - 9.3e-29 100.3 0.2 1.3e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF538 PF04398.7 EON96624.1 - 0.0045 17.2 0.0 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF538 Na_Ca_ex PF01699.19 EON96626.1 - 5.6e-25 87.5 22.3 3.4e-14 52.6 3.0 2.7 2 2 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.7 EON96626.1 - 0.00037 19.6 0.0 0.00037 19.6 0.0 2.0 3 0 0 3 3 3 1 7tm Chemosensory receptor DUF3169 PF11368.3 EON96626.1 - 0.034 13.3 0.2 0.034 13.3 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4149 PF13664.1 EON96626.1 - 1.5 8.9 20.6 0.98 9.5 3.4 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4149) DUF4131 PF13567.1 EON96626.1 - 4.2 6.7 7.0 30 3.9 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_8 PF05148.10 EON96627.1 - 2.1e-58 197.5 0.2 8.3e-56 189.0 0.0 3.3 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EON96627.1 - 1.2e-06 28.9 0.0 5.6e-06 26.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON96627.1 - 0.02 15.2 0.1 0.54 10.6 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EON96627.1 - 0.041 13.4 0.0 3 7.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_1g PF09334.6 EON96627.1 - 0.042 12.5 0.0 0.042 12.5 0.0 1.9 2 0 0 2 2 1 0 tRNA synthetases class I (M) PqqD PF05402.7 EON96627.1 - 0.056 13.4 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Mem_trans PF03547.13 EON96627.1 - 0.062 11.5 0.1 0.064 11.5 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_32 PF13679.1 EON96627.1 - 0.29 10.8 0.0 0.29 10.8 0.0 2.4 2 1 0 2 2 1 0 Methyltransferase domain SAPS PF04499.10 EON96627.1 - 0.38 9.3 8.7 0.67 8.5 6.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 EON96627.1 - 7.9 4.7 13.8 11 4.2 9.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.12 EON96627.1 - 8 5.1 9.3 13 4.5 6.4 1.4 1 0 0 1 1 1 0 Presenilin CPSase_L_D2 PF02786.12 EON96628.1 - 1.3e-112 374.2 0.2 1.7e-83 279.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EON96628.1 - 1.7e-45 154.8 0.0 3.6e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EON96628.1 - 1.3e-44 150.8 0.0 2.8e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_chain PF00289.17 EON96628.1 - 1.4e-41 141.0 0.0 1e-20 73.8 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EON96628.1 - 2.2e-41 140.4 0.0 5.2e-41 139.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 EON96628.1 - 6.1e-39 132.9 0.0 1.3e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATP-grasp_4 PF13535.1 EON96628.1 - 3.7e-36 124.5 0.2 2.5e-23 82.7 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EON96628.1 - 1.2e-33 116.1 0.0 2.9e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EON96628.1 - 1.4e-22 79.3 0.0 7.3e-22 77.1 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EON96628.1 - 3.2e-22 78.7 0.1 1.2e-12 47.2 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EON96628.1 - 2e-16 59.8 0.1 7.1e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EON96628.1 - 5.8e-15 55.2 0.5 2.7e-07 30.2 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 EON96628.1 - 1.2e-06 28.1 0.2 3.1e-05 23.5 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EON96628.1 - 6.8e-06 26.0 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EON96628.1 - 0.0015 17.9 0.1 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EON96628.1 - 0.0043 16.6 0.1 2.5 7.5 0.0 2.9 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FA_desaturase_2 PF03405.9 EON96628.1 - 0.24 10.1 0.0 0.46 9.1 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Transglut_core PF01841.14 EON96629.1 - 1.6e-12 47.6 0.2 3.4e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily RRM_1 PF00076.17 EON96630.1 - 5.1e-33 112.5 0.0 7.1e-16 57.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON96630.1 - 2.4e-17 62.6 0.0 6e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON96630.1 - 5.5e-16 58.1 0.0 2.8e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EON96630.1 - 0.002 17.5 0.2 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 EON96630.1 - 0.1 12.3 0.1 4.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Limkain b1 2-Hacid_dh_C PF02826.14 EON96631.1 - 4.1e-52 175.8 0.0 6.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON96631.1 - 2.7e-16 59.2 0.0 3.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EON96631.1 - 0.00027 20.7 0.0 0.00077 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1777 PF08648.7 EON96632.1 - 1.5e-24 86.7 8.4 2.3e-24 86.0 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Daxx PF03344.10 EON96632.1 - 0.11 10.9 4.5 0.13 10.7 3.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EON96632.1 - 0.13 10.9 6.7 0.18 10.5 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EON96632.1 - 1.7 6.4 7.4 1.9 6.3 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family UQ_con PF00179.21 EON96633.1 - 1e-50 170.8 0.0 1.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hydrolase PF00702.21 EON96634.1 - 6.4e-17 62.6 0.0 5.2e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EON96634.1 - 3.9e-11 43.4 0.0 1.7e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON96634.1 - 8.6e-05 22.4 0.0 0.00057 19.7 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EON96634.1 - 0.0004 20.0 0.0 0.00082 19.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L28e PF01778.12 EON96635.1 - 3.7e-31 107.9 1.7 7.3e-31 106.9 1.2 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EON96635.1 - 2.6e-19 69.1 31.6 2.6e-19 69.1 21.9 3.8 3 1 0 3 3 3 1 Mak16 protein C-terminal region TFIIA PF03153.8 EON96635.1 - 0.0022 17.9 12.8 0.0027 17.6 8.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EON96635.1 - 9.5 4.1 20.9 18 3.1 14.5 1.5 1 0 0 1 1 1 0 CDC45-like protein MIF4G_like PF09088.6 EON96636.1 - 2.1e-81 271.9 0.6 3.5e-81 271.2 0.4 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EON96636.1 - 1.2e-52 178.6 0.0 1.8e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G like CLPTM1 PF05602.7 EON96637.1 - 4.2e-158 526.6 0.0 5.1e-158 526.3 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) His_Phos_2 PF00328.17 EON96638.1 - 3.7e-30 105.4 0.0 5.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA-synt_1 PF00133.17 EON96639.1 - 2.7e-46 157.7 3.7 1e-17 63.3 0.2 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EON96639.1 - 1.8e-43 148.0 0.0 5e-43 146.5 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EON96639.1 - 9.4e-32 110.1 0.0 2.6e-23 82.3 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EON96639.1 - 5.7e-13 48.8 0.1 1.4e-12 47.6 0.1 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EON96639.1 - 0.002 17.2 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EON96639.1 - 0.0097 14.7 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EON96639.1 - 0.12 11.0 0.4 9.2 4.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Dynamin_M PF01031.15 EON96640.1 - 1.9e-104 348.6 0.0 4.2e-104 347.4 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EON96640.1 - 7.6e-56 188.5 0.0 1.5e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EON96640.1 - 7.5e-29 99.4 5.8 7.5e-29 99.4 4.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EON96640.1 - 0.00027 20.8 0.2 0.0042 17.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EON96640.1 - 0.013 16.0 0.0 0.039 14.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DUF2226 PF09987.4 EON96640.1 - 0.025 13.7 0.1 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) Actin PF00022.14 EON96641.1 - 2.9e-159 529.7 0.0 3.3e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EON96641.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SMI1_KNR4 PF09346.5 EON96642.1 - 9.8e-32 109.7 0.0 1.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec16_C PF12931.2 EON96643.1 - 5.7e-82 275.6 0.0 8.1e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EON96643.1 - 5.2e-19 68.3 4.7 2.1e-17 63.1 0.8 2.7 2 1 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region zf-RING_2 PF13639.1 EON96644.1 - 8.5e-10 38.3 2.0 8.5e-10 38.3 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EON96644.1 - 3.6e-08 33.2 3.6 4.2e-08 33.0 0.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON96644.1 - 3.8e-08 32.8 3.5 1.6e-07 30.9 1.1 2.4 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON96644.1 - 1.5e-07 30.9 1.4 1.5e-07 30.9 1.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EON96644.1 - 1.7e-07 31.2 0.2 1.7e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EON96644.1 - 5.1e-06 26.1 1.3 5.1e-06 26.1 0.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EON96644.1 - 0.00036 20.3 0.8 0.00036 20.3 0.6 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EON96644.1 - 0.0017 18.0 2.8 0.0063 16.2 0.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger HCV_NS4a PF01006.15 EON96644.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a YdjO PF14169.1 EON96644.1 - 0.094 12.1 1.0 13 5.3 0.0 3.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-Nse PF11789.3 EON96644.1 - 0.13 11.7 2.2 0.31 10.5 1.5 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EON96644.1 - 0.17 11.8 0.4 0.17 11.8 0.3 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 EON96644.1 - 0.36 10.8 4.7 36 4.4 0.1 3.5 3 0 0 3 3 3 0 zinc-finger zf-RING_4 PF14570.1 EON96644.1 - 2.6 7.7 8.3 0.46 10.1 2.0 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Trypan_PARP PF05887.6 EON96644.1 - 6.1 6.6 13.7 12 5.7 9.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-Di19 PF05605.7 EON96644.1 - 6.1 7.0 8.3 29 4.8 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_63 PF03200.11 EON96645.1 - 1.3e-248 826.9 0.1 1.3e-247 823.6 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EON96645.1 - 7.9e-05 21.4 0.0 0.00013 20.7 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EON96645.1 - 0.0015 17.3 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DER1 PF04511.10 EON96646.1 - 2.4e-05 23.9 0.3 2.6e-05 23.8 0.2 1.0 1 0 0 1 1 1 1 Der1-like family AA_permease_2 PF13520.1 EON96647.1 - 1.9e-62 211.1 43.1 2.7e-62 210.7 29.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON96647.1 - 6e-28 97.4 30.2 6e-28 97.4 20.9 2.0 2 0 0 2 2 2 1 Amino acid permease UPF0220 PF05255.6 EON96648.1 - 4e-64 214.8 2.2 4.4e-64 214.7 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3341 PF11821.3 EON96648.1 - 0.082 12.3 0.7 0.23 10.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) UCR_6-4kD PF08997.5 EON96648.1 - 0.26 11.0 1.5 0.65 9.7 0.2 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein LTV PF04180.9 EON96649.1 - 5.2e-96 322.7 12.0 5.9e-96 322.5 8.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein RabGAP-TBC PF00566.13 EON96650.1 - 1.3e-37 129.3 1.3 2.2e-37 128.6 0.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EON96650.1 - 2.5e-10 40.0 0.0 2.2e-05 23.8 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) Proteasome PF00227.21 EON96651.1 - 5.3e-51 172.6 0.1 6.8e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EON96651.1 - 2.7e-11 42.5 0.2 4.8e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ArgJ PF01960.13 EON96652.1 - 4e-143 476.5 0.6 4.5e-143 476.3 0.4 1.0 1 0 0 1 1 1 1 ArgJ family Fes1 PF08609.5 EON96653.1 - 1.3e-31 108.9 2.7 1.6e-31 108.6 0.9 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EON96653.1 - 1.4e-10 41.3 2.5 1.7e-05 25.0 0.0 2.4 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EON96653.1 - 2.9e-06 27.6 0.2 0.022 15.2 0.0 3.1 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EON96653.1 - 4.1e-06 26.4 0.1 0.049 13.7 0.0 3.0 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EON96653.1 - 3e-05 23.6 0.0 0.051 13.4 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat adh_short_C2 PF13561.1 EON96654.1 - 6.6e-22 78.4 0.0 1.8e-13 50.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON96654.1 - 3.7e-15 56.2 0.3 1e-14 54.8 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96654.1 - 4.3e-10 39.5 0.0 6.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EON96654.1 - 1.6e-05 23.9 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 EON96654.1 - 0.0022 17.8 0.7 0.0037 17.0 0.5 1.6 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EON96654.1 - 0.039 14.0 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EON96654.1 - 0.069 12.5 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EON96654.1 - 0.12 12.9 0.2 0.39 11.3 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Med6 PF04934.9 EON96655.1 - 7.4e-40 135.7 0.1 1.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component zf-C2H2 PF00096.21 EON96656.1 - 9.6e-06 25.6 10.2 0.025 14.9 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON96656.1 - 3.5e-05 23.8 9.6 0.013 15.7 2.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EON96656.1 - 0.0048 17.1 13.3 0.015 15.5 3.3 3.4 3 1 0 3 3 3 2 Zinc-finger double domain DUF3684 PF12449.3 EON96657.1 - 0 1428.1 0.0 0 1427.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EON96657.1 - 1.4e-05 24.7 0.0 3.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EON96657.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.1 EON96657.1 - 0.035 14.0 0.6 0.077 12.9 0.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3420 PF11900.3 EON96657.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) FH2 PF02181.18 EON96658.1 - 5.3e-82 275.6 9.5 5.3e-82 275.6 6.6 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EON96658.1 - 9.6e-62 207.6 0.2 4.3e-61 205.5 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EON96658.1 - 1.3e-55 187.9 7.4 7.3e-55 185.4 1.3 3.2 2 1 1 3 3 3 2 Diaphanous FH3 Domain Pkinase PF00069.20 EON96659.1 - 1.5e-63 214.3 0.0 1.8e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96659.1 - 1.1e-25 90.2 0.0 1.4e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON96659.1 - 7.9e-08 31.6 0.0 4.4e-07 29.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EON96659.1 - 0.0026 17.5 0.1 0.012 15.3 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EON96659.1 - 0.056 13.0 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 EON96660.1 - 3.2e-16 59.6 0.4 5.1e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96660.1 - 8.5e-07 28.8 0.2 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Hus1 PF04005.7 EON96661.1 - 2.3e-94 315.6 0.0 2.6e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Cyclase PF04199.8 EON96662.1 - 2e-10 40.6 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Vps55 PF04133.9 EON96663.1 - 2.5e-48 162.7 6.4 2.8e-48 162.6 4.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 WD40 PF00400.27 EON96664.1 - 6.4e-19 67.0 0.8 1e-09 37.8 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat CLTH PF10607.4 EON96664.1 - 2.6e-05 23.9 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Glyco_hydro_18 PF00704.23 EON96665.1 - 1e-11 44.8 0.0 2.2e-11 43.8 0.0 1.4 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EON96666.1 - 5.7e-70 235.4 0.0 7.5e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96666.1 - 9.1e-50 169.1 0.0 1.3e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON96666.1 - 2.2e-06 26.8 0.0 7.2e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like AMP-binding PF00501.23 EON96667.1 - 3e-63 213.6 0.0 5.1e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EON96667.1 - 1.5e-52 178.0 0.0 9.5e-50 168.8 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EON96667.1 - 1.5e-14 54.0 0.0 2.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON96667.1 - 1.7e-09 36.7 0.0 3.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EON96667.1 - 7.2e-09 35.7 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EON96667.1 - 3.9e-07 30.9 0.0 1.6e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EON96667.1 - 2.7e-05 24.2 0.1 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EON96667.1 - 0.00093 19.1 0.0 0.0028 17.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EON96667.1 - 0.0074 15.2 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EON96667.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 EON96667.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EON96667.1 - 0.068 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 KR domain DUF3384 PF11864.3 EON96668.1 - 2.5e-106 355.9 0.9 2.5e-106 355.9 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EON96668.1 - 4e-56 189.3 0.0 8.4e-56 188.3 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EON96668.1 - 1.5e-33 116.3 0.5 2.6e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 Tuberin LSM PF01423.17 EON96669.1 - 4.8e-15 54.8 0.3 6.7e-15 54.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain HA2 PF04408.18 EON96670.1 - 5.3e-19 68.1 0.0 5.3e-19 68.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EON96670.1 - 1.4e-14 53.6 0.1 6.8e-14 51.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EON96670.1 - 2.1e-12 46.8 0.0 6.3e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EON96670.1 - 5.2e-08 32.5 0.0 2.7e-07 30.2 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EON96670.1 - 7.1e-05 22.9 0.0 0.00025 21.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EON96670.1 - 0.00083 18.3 0.0 0.0044 15.9 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.11 EON96670.1 - 0.02 14.1 0.1 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EON96670.1 - 0.042 13.3 0.2 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EON96670.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 EON96670.1 - 0.092 12.5 3.5 4 7.2 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF1996 PF09362.5 EON96671.1 - 7.8e-74 248.2 0.0 1.1e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PLRV_ORF5 PF01690.12 EON96671.1 - 8.8 5.3 9.8 13 4.8 6.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein adh_short PF00106.20 EON96672.1 - 8e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96672.1 - 5.9e-06 26.2 0.0 8.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EON96672.1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Longin PF13774.1 EON96673.1 - 1.1e-28 98.5 0.1 2.1e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EON96673.1 - 2.7e-15 55.7 0.1 5.2e-15 54.8 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 EON96673.1 - 0.018 14.8 0.6 0.018 14.8 0.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 EON96673.1 - 0.068 13.5 0.6 6.4 7.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) RF-1 PF00472.15 EON96675.1 - 2.4e-15 56.2 4.4 3.3e-15 55.8 3.0 1.2 1 0 0 1 1 1 1 RF-1 domain DUF4502 PF14950.1 EON96675.1 - 0.019 14.1 2.1 0.024 13.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) MMR_HSR1 PF01926.18 EON96676.1 - 5.2e-17 61.8 0.4 2.9e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EON96676.1 - 3.2e-08 33.0 0.2 1.4e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EON96676.1 - 9.9e-05 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EON96676.1 - 0.00056 19.7 0.6 0.025 14.3 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.11 EON96676.1 - 0.0017 17.4 0.1 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EON96676.1 - 0.035 14.6 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TRAP_alpha PF03896.11 EON96676.1 - 0.34 9.8 4.2 0.62 9.0 2.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ASXH PF13919.1 EON96677.1 - 2.6e-25 88.8 2.1 2.6e-25 88.8 1.4 1.5 2 0 0 2 2 2 1 Asx homology domain Phosphoesterase PF04185.9 EON96678.1 - 1.4e-77 261.4 5.3 1.8e-77 261.0 3.7 1.1 1 0 0 1 1 1 1 Phosphoesterase family Lysine_decarbox PF03641.9 EON96679.1 - 5.5e-31 107.1 0.0 8.3e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Aminotran_5 PF00266.14 EON96680.1 - 1.2e-29 103.2 0.0 8.7e-17 60.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V ABC_tran PF00005.22 EON96681.1 - 6.2e-15 55.7 0.0 6.8e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EON96681.1 - 3.3e-10 40.4 0.0 0.00049 20.1 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EON96681.1 - 0.00072 19.0 0.1 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EON96681.1 - 0.00078 16.9 0.2 0.001 16.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 EON96681.1 - 0.0011 18.0 0.0 0.19 10.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EON96681.1 - 0.0028 16.9 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EON96681.1 - 0.0081 16.1 0.9 0.032 14.2 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EON96681.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EON96681.1 - 0.016 14.6 0.3 0.045 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EON96681.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EON96681.1 - 0.019 14.9 0.4 0.041 13.8 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EON96681.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EON96681.1 - 0.023 15.4 0.6 0.047 14.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON96681.1 - 0.058 13.5 0.4 0.35 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EON96681.1 - 0.06 13.5 0.1 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EON96681.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arf PF00025.16 EON96681.1 - 0.088 12.0 0.3 0.21 10.8 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family DUF258 PF03193.11 EON96681.1 - 0.088 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EON96681.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EON96681.1 - 0.13 12.2 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EON96681.1 - 0.14 11.7 0.2 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 EON96681.1 - 0.18 10.2 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EON96681.1 - 0.2 10.7 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin DUF3317 PF11779.3 EON96682.1 - 8.2e-16 57.1 7.2 1.1e-15 56.8 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Sec8_exocyst PF04048.9 EON96683.1 - 1.2e-46 157.8 0.0 2.9e-46 156.6 0.0 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EON96683.1 - 5e-09 35.4 0.4 1e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) WD40 PF00400.27 EON96684.1 - 2e-21 74.9 0.0 4.9e-05 23.0 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF4596 PF15363.1 EON96684.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Chorismate_bind PF00425.13 EON96685.1 - 1.1e-51 175.6 0.1 1.3e-51 175.4 0.1 1.0 1 0 0 1 1 1 1 chorismate binding enzyme DUF4315 PF14193.1 EON96685.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) FTA2 PF13095.1 EON96686.1 - 0.52 9.8 3.1 2.8 7.4 1.5 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1168 PF06658.7 EON96686.1 - 0.54 9.7 9.8 1.1 8.7 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CAS_CSE1 PF03378.10 EON96687.1 - 2.2e-175 583.1 0.0 5.7e-175 581.7 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EON96687.1 - 3.5e-153 509.5 1.0 5.3e-153 508.9 0.7 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EON96687.1 - 4.7e-11 42.4 0.1 1.5e-10 40.8 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EON96687.1 - 0.0019 18.1 1.1 0.021 14.7 0.1 3.3 3 1 1 4 4 4 1 Exportin 1-like protein DUF1529 PF07485.6 EON96687.1 - 0.032 13.9 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) TRAPPC9-Trs120 PF08626.6 EON96688.1 - 3.6e-59 200.1 0.0 6.8e-59 199.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ribosomal_L5_C PF00673.16 EON96689.1 - 9e-24 83.0 0.0 1.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EON96689.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L5 Urm1 PF09138.6 EON96690.1 - 2.4e-33 114.1 0.0 2.8e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EON96690.1 - 0.0062 16.9 0.0 0.0078 16.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family DnaJ PF00226.26 EON96691.1 - 0.0081 15.8 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain CoA_transf_3 PF02515.12 EON96692.1 - 3e-53 179.9 0.0 4.2e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Transp_cyt_pur PF02133.10 EON96694.1 - 6.6e-07 28.2 0.4 7.3e-07 28.0 0.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 EON96696.1 - 9e-17 60.7 4.7 1e-16 60.5 3.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.4 EON96698.1 - 1.5e-14 53.9 1.9 2.1e-14 53.4 1.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HRDC PF00570.18 EON96698.1 - 0.12 12.1 0.3 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 HRDC domain 2-Hacid_dh_C PF02826.14 EON96701.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vps23_core PF09454.5 EON96702.1 - 0.036 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Vps23 core domain p450 PF00067.17 EON96703.1 - 2.7e-41 141.5 0.2 1.6e-24 86.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3328 PF11807.3 EON96705.1 - 1.8e-28 99.7 0.6 2.6e-28 99.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RCR PF12273.3 EON96705.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TPP_enzyme_N PF02776.13 EON96706.1 - 1.5e-36 125.4 0.1 1.3e-35 122.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EON96706.1 - 8.7e-25 87.0 0.2 2.6e-23 82.3 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EON96706.1 - 2.2e-23 82.5 0.0 6.2e-23 81.0 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EON96706.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Sugar_tr PF00083.19 EON96707.1 - 2.6e-75 253.7 26.8 3e-75 253.5 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96707.1 - 9.2e-17 60.7 44.1 1.3e-15 57.0 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.16 EON96708.1 - 1.6e-28 99.5 4.5 3.8e-14 52.2 0.1 2.2 2 0 0 2 2 2 2 POT family CcmH PF03918.9 EON96708.1 - 0.086 11.8 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein adh_short PF00106.20 EON96709.1 - 5.9e-25 88.1 0.1 9.3e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96709.1 - 7.3e-12 45.5 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96709.1 - 5.1e-08 32.7 0.2 1.2e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EON96709.1 - 1.1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 EON96709.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 EON96709.1 - 0.016 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EON96709.1 - 0.021 14.9 0.1 0.058 13.4 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4038 PF13204.1 EON96709.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Polysacc_synt_2 PF02719.10 EON96709.1 - 0.027 13.3 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EON96709.1 - 0.098 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SWIRM PF04433.12 EON96710.1 - 3.3e-12 46.3 0.0 8.8e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EON96710.1 - 2.3e-07 30.7 0.0 1e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SHOCT PF09851.4 EON96710.1 - 0.062 12.7 0.5 0.062 12.7 0.4 2.2 2 0 0 2 2 2 0 Short C-terminal domain TPR_11 PF13414.1 EON96711.1 - 2e-05 24.1 0.8 5.3e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.1 EON96711.1 - 0.0004 20.3 0.3 0.00086 19.3 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EON96711.1 - 0.00053 19.4 1.2 0.32 10.6 2.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EON96711.1 - 0.0012 18.6 3.4 0.015 15.1 2.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EON96711.1 - 0.0012 18.6 0.3 0.0027 17.5 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON96711.1 - 0.0054 17.3 0.5 0.013 16.1 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EON96711.1 - 0.0056 17.0 1.9 0.0099 16.1 0.8 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EON96711.1 - 0.021 14.7 0.5 0.29 11.0 0.2 2.3 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1268 PF06896.6 EON96711.1 - 0.028 14.7 0.1 0.046 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) U-box PF04564.10 EON96711.1 - 0.044 13.7 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 U-box domain PhyH PF05721.8 EON96712.1 - 3.4e-17 63.1 0.0 4.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GalP_UDP_transf PF01087.17 EON96713.1 - 3.2e-71 239.1 0.1 5.8e-70 235.0 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EON96713.1 - 3.4e-55 186.1 0.0 6.3e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EON96713.1 - 9.9e-06 26.0 0.0 0.00055 20.4 0.0 2.5 2 1 0 2 2 2 1 HIT domain FAD_binding_4 PF01565.18 EON96715.1 - 7.5e-21 74.0 0.4 1.1e-20 73.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON96715.1 - 0.002 17.9 0.3 0.006 16.4 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like ECH PF00378.15 EON96716.1 - 2.2e-47 161.2 0.0 3e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EON96716.1 - 0.051 13.3 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 adh_short PF00106.20 EON96717.1 - 9e-19 68.0 0.9 1.2e-18 67.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96717.1 - 6.8e-16 58.7 0.2 1.3e-10 41.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96717.1 - 0.0002 21.1 0.4 0.00026 20.7 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EON96717.1 - 0.05 13.2 1.8 0.063 12.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EON96717.1 - 0.097 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.18 EON96717.1 - 0.14 12.0 1.0 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.17 EON96718.1 - 5.1e-19 68.4 0.1 5.4e-17 61.8 0.1 2.3 1 1 0 1 1 1 1 Subtilase family PHO4 PF01384.15 EON96719.1 - 7.5e-57 192.4 7.4 2.5e-56 190.6 5.2 1.7 1 1 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 EON96720.1 - 5.4e-17 61.5 16.0 1.7e-08 33.5 4.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EON96720.1 - 5.6e-05 23.4 0.1 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1228 PF06779.9 EON96720.1 - 0.17 11.9 2.1 9.8 6.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1228) Glyco_hydro_28 PF00295.12 EON96721.1 - 8.2e-30 103.8 0.2 9.1e-18 64.2 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 DUF1620 PF07774.8 EON96721.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) PWI PF01480.12 EON96722.1 - 1.5e-10 41.0 0.1 4.3e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 PWI domain Mg_trans_NIPA PF05653.9 EON96724.1 - 6.1e-90 301.2 25.9 8.6e-90 300.7 18.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EON96724.1 - 3.5e-08 33.6 3.9 3.5e-08 33.6 2.7 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EON96724.1 - 8.5e-06 25.8 6.8 8.5e-06 25.8 4.7 2.8 2 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EON96724.1 - 2.8 6.6 17.3 31 3.2 11.8 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF3433 PF11915.3 EON96725.1 - 1.5e-16 60.3 3.0 1.5e-16 60.3 2.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Nucleoporin_C PF03177.9 EON96726.1 - 9e-136 453.7 2.1 1.1e-135 453.4 1.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EON96726.1 - 7.9e-88 295.0 0.0 1e-87 294.6 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like ABC_membrane PF00664.18 EON96727.1 - 1.2e-70 238.0 26.7 3.8e-41 141.3 10.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EON96727.1 - 8.3e-31 107.1 0.2 3e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EON96727.1 - 7.3e-07 28.6 2.3 0.00013 21.3 1.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EON96727.1 - 8.1e-06 26.0 0.1 0.0017 18.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EON96727.1 - 0.00015 20.5 0.1 0.016 13.8 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EON96727.1 - 0.00044 19.7 0.4 0.0012 18.3 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EON96727.1 - 0.028 13.5 0.2 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EON96727.1 - 0.051 13.4 2.7 0.22 11.4 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EON96727.1 - 0.057 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EON96727.1 - 0.062 13.6 0.1 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EON96727.1 - 0.083 12.8 0.2 0.27 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EON96727.1 - 0.085 12.9 0.2 0.55 10.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EON96728.1 - 1.3e-24 87.3 0.1 3e-24 86.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96728.1 - 1.7e-08 34.3 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON96728.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4286 PF14114.1 EON96728.1 - 0.00075 19.7 0.0 0.017 15.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) Esterase PF00756.15 EON96728.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 EON96728.1 - 0.003 18.4 0.0 0.24 12.3 0.0 2.5 2 0 0 2 2 2 1 EthD domain Abhydrolase_2 PF02230.11 EON96728.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pho88 PF10032.4 EON96729.1 - 2.4e-81 271.5 0.1 2.7e-81 271.4 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 EON96730.1 - 3.6e-28 96.9 2.6 8e-28 95.7 1.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EON96730.1 - 0.018 14.6 9.5 0.018 14.6 6.6 2.4 3 0 0 3 3 3 0 XPA protein N-terminal ArfGap PF01412.13 EON96730.1 - 1.4 8.6 7.6 0.2 11.4 2.1 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf YhfH PF14149.1 EON96730.1 - 7.3 6.4 12.9 1.2 8.9 0.2 2.6 2 1 0 2 2 2 0 YhfH-like protein Striatin PF08232.7 EON96731.1 - 4.3e-33 114.4 7.0 1.3e-32 112.9 4.9 1.8 1 1 0 1 1 1 1 Striatin family WD40 PF00400.27 EON96731.1 - 9.8e-32 107.6 12.4 9e-09 34.8 0.0 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat MFS_1 PF07690.11 EON96732.1 - 1.6e-30 106.0 18.9 2.1e-30 105.6 13.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON96732.1 - 1.6e-14 53.3 2.2 2.2e-14 52.8 1.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EON96732.1 - 0.00038 18.7 4.9 0.00053 18.3 3.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transp_cyt_pur PF02133.10 EON96734.1 - 1.6e-14 53.3 4.1 2e-14 53.0 2.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sugar_tr PF00083.19 EON96735.1 - 3.7e-74 249.9 30.2 4.3e-74 249.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON96735.1 - 3.5e-21 75.3 33.5 3.7e-17 62.0 8.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON96735.1 - 1.5 7.1 31.4 0.61 8.4 3.3 3.5 2 1 0 3 3 3 0 MFS/sugar transport protein FAD_binding_4 PF01565.18 EON96736.1 - 9.7e-11 41.2 0.2 2e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON96736.1 - 0.008 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like CFEM PF05730.6 EON96737.1 - 2.2e-11 43.3 4.4 2.2e-11 43.3 3.0 2.8 3 1 0 3 3 3 1 CFEM domain RdRP PF05183.7 EON96738.1 - 2.3e-142 475.6 0.0 1.4e-141 473.1 0.0 1.9 1 1 0 1 1 1 1 RNA dependent RNA polymerase DUF1826 PF08856.6 EON96738.1 - 0.14 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) NAD_binding_8 PF13450.1 EON96739.1 - 5.3e-13 48.7 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EON96739.1 - 8.4e-09 35.0 0.5 1.3e-08 34.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EON96739.1 - 2.7e-06 26.4 0.3 3.8e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EON96739.1 - 3.1e-06 26.5 0.0 3.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EON96739.1 - 3.4e-06 25.7 0.1 5.8e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EON96739.1 - 4.3e-06 26.9 0.0 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON96739.1 - 9.5e-06 24.7 0.5 2.3e-05 23.4 0.5 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON96739.1 - 0.00018 21.4 0.1 0.00044 20.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EON96739.1 - 0.00027 20.3 0.1 0.00086 18.7 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EON96739.1 - 0.00035 19.7 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EON96739.1 - 0.00038 20.7 0.0 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON96739.1 - 0.0012 18.0 0.2 0.0017 17.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EON96739.1 - 0.0049 15.7 0.1 0.0077 15.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EON96739.1 - 0.038 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EON96739.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EON96739.1 - 0.082 11.5 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EON96739.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding peroxidase PF00141.18 EON96740.1 - 1.1e-30 106.8 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EON96740.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) Amidase PF01425.16 EON96741.1 - 1.1e-71 242.0 0.4 1.5e-71 241.6 0.3 1.1 1 0 0 1 1 1 1 Amidase R3H PF01424.17 EON96742.1 - 6.3e-11 41.8 0.0 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EON96742.1 - 2.5e-06 27.3 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON96742.1 - 9e-05 22.0 0.0 0.0002 20.9 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON96742.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EON96742.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 Abhydrolase_6 PF12697.2 EON96743.1 - 7e-29 101.3 0.7 8.8e-29 101.0 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96743.1 - 1.6e-10 40.9 0.1 2.9e-10 40.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96743.1 - 3.2e-10 39.9 0.1 0.00072 19.1 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON96743.1 - 8.2e-10 38.3 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EON96743.1 - 0.0041 15.6 0.0 0.021 13.2 0.0 1.9 1 1 0 1 1 1 1 Ndr family Ribosomal_S19 PF00203.16 EON96745.1 - 4.5e-23 80.6 0.0 7e-23 80.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 APC10 PF03256.11 EON96747.1 - 8.1e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) adh_short PF00106.20 EON96748.1 - 4.2e-22 78.8 0.1 6e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96748.1 - 3.3e-11 43.4 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96748.1 - 2e-06 27.6 0.1 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON96748.1 - 3.9e-06 26.4 0.1 2.8e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON96748.1 - 9.8e-05 22.4 0.1 0.00017 21.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EON96748.1 - 0.051 12.4 0.1 0.08 11.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EON96748.1 - 0.054 12.3 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EON96748.1 - 0.057 12.6 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EON96748.1 - 0.13 10.9 0.1 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_S8 PF00082.17 EON96749.1 - 1.5e-45 155.5 4.8 2.7e-45 154.6 3.3 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EON96749.1 - 7.4e-11 42.4 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EON96749.1 - 3.8e-08 32.9 0.0 1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 PA domain Cellulase PF00150.13 EON96750.1 - 1.2e-52 178.8 5.5 1.5e-52 178.5 3.8 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EthD PF07110.6 EON96751.1 - 0.0012 19.7 0.0 0.0013 19.6 0.0 1.1 1 0 0 1 1 1 1 EthD domain Cytokin-bind PF09265.5 EON96751.1 - 0.089 11.9 0.0 0.089 11.9 0.0 1.0 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Mre11_DNA_bind PF04152.9 EON96752.1 - 3.1e-53 180.2 1.3 3.1e-53 180.2 0.9 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EON96752.1 - 1.8e-25 89.5 2.9 2.6e-25 88.9 2.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EON96752.1 - 1.2e-08 34.9 0.1 2.7e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RST PF12174.3 EON96752.1 - 1.3 8.8 4.1 7.2 6.4 1.1 2.3 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain BC10 PF06726.7 EON96753.1 - 2.9e-17 62.4 11.2 4.9e-17 61.6 7.8 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Transp_cyt_pur PF02133.10 EON96754.1 - 8.5e-45 153.0 14.9 1.2e-44 152.6 10.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_C47 PF05543.8 EON96754.1 - 0.01 15.2 0.2 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 APC10 PF03256.11 EON96755.1 - 1.6e-22 80.0 0.0 2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) GTP_CH_N PF12471.3 EON96756.1 - 1.2e-89 299.0 0.0 1.7e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EON96756.1 - 3.6e-17 62.1 0.0 8.3e-17 60.9 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II PhyH PF05721.8 EON96757.1 - 8.7e-15 55.3 0.0 1.1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Na_Ca_ex PF01699.19 EON96758.1 - 8.7e-33 112.8 22.8 2e-20 72.8 5.7 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EON96758.1 - 1.9e-15 57.0 12.0 1.9e-15 57.0 8.3 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF307) Y_phosphatase PF00102.22 EON96759.1 - 3.1e-59 200.1 0.0 1.2e-33 116.3 0.0 3.8 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EON96759.1 - 4.4e-12 46.3 0.0 1.6e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EON96759.1 - 0.016 15.4 0.4 0.048 13.9 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 EON96759.1 - 0.018 14.6 0.1 0.043 13.3 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MFS_1 PF07690.11 EON96760.1 - 4.1e-10 38.9 24.9 4.9e-09 35.3 17.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SNAPc_SNAP43 PF09808.4 EON96760.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF687 PF05095.7 EON96760.1 - 0.031 12.6 0.4 0.043 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) HlyIII PF03006.15 EON96760.1 - 0.35 10.2 15.1 0.18 11.2 5.0 2.5 2 1 0 2 2 2 0 Haemolysin-III related Histone PF00125.19 EON96761.1 - 4.6e-22 77.9 0.1 5.9e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EON96761.1 - 4.3e-05 23.4 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA PF00004.24 EON96762.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EON96762.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EON96762.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EON96762.1 - 3.3e-06 27.2 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EON96762.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON96762.1 - 6.2e-05 23.7 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EON96762.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EON96762.1 - 0.00013 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EON96762.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EON96762.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EON96762.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EON96762.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EON96762.1 - 0.0022 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EON96762.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EON96762.1 - 0.0038 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON96762.1 - 0.006 16.8 0.1 0.028 14.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EON96762.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EON96762.1 - 0.0073 15.4 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EON96762.1 - 0.017 14.5 0.1 0.075 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EON96762.1 - 0.018 14.2 0.0 0.07 12.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EON96762.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EON96762.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EON96762.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EON96762.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.4 EON96762.1 - 0.037 13.9 0.2 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 EON96762.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 EON96762.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EON96762.1 - 0.049 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EON96762.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EON96762.1 - 0.099 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Phosphoesterase PF04185.9 EON96763.1 - 9e-32 110.6 3.4 2e-31 109.5 2.4 1.5 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 EON96763.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase TFIID_30kDa PF03540.8 EON96764.1 - 3.4e-26 90.8 0.4 5.2e-26 90.2 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Rep_fac_C PF08542.6 EON96765.1 - 5.3e-16 58.3 0.0 1.4e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EON96765.1 - 1.5e-15 57.5 0.0 2.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EON96765.1 - 2.2e-13 50.1 0.0 5.9e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EON96765.1 - 8.8e-09 34.5 0.0 1.8e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EON96765.1 - 7.5e-08 32.5 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON96765.1 - 1.1e-06 28.7 0.0 7.9e-05 22.7 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EON96765.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EON96765.1 - 2e-06 27.4 0.0 5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EON96765.1 - 8.6e-06 25.4 0.3 0.00034 20.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EON96765.1 - 1.2e-05 25.0 0.4 5.3e-05 22.9 0.1 2.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EON96765.1 - 2.1e-05 24.4 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EON96765.1 - 4.5e-05 22.6 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EON96765.1 - 0.00011 21.1 0.0 0.36 9.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EON96765.1 - 0.00015 20.7 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EON96765.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EON96765.1 - 0.00017 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DNA_pol3_delta PF06144.8 EON96765.1 - 0.00038 20.0 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 EON96765.1 - 0.00067 18.7 0.0 0.00098 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EON96765.1 - 0.00086 18.5 0.0 0.4 9.8 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein Mg_chelatase PF01078.16 EON96765.1 - 0.00088 18.4 0.1 0.005 16.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EON96765.1 - 0.00097 18.7 0.1 0.005 16.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EON96765.1 - 0.0055 16.2 0.0 0.1 12.0 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.1 EON96765.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EON96765.1 - 0.0075 15.6 0.1 0.025 13.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EON96765.1 - 0.0087 15.5 0.2 1.9 7.8 0.0 2.5 2 1 1 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EON96765.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EON96765.1 - 0.018 14.4 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EON96765.1 - 0.025 15.3 0.0 0.05 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EON96765.1 - 0.034 13.9 0.0 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 EON96765.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EON96765.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EON96765.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DUF925 PF06042.6 EON96766.1 - 2.9e-48 163.5 0.0 3.4e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF925) Glyco_hydro_75 PF07335.6 EON96767.1 - 2.1e-41 141.4 0.0 2.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 TIP_N PF12457.3 EON96767.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal DUF1688 PF07958.6 EON96768.1 - 3.2e-160 533.2 0.0 3.6e-160 533.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) AAA_2 PF07724.9 EON96768.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Methyltransf_23 PF13489.1 EON96769.1 - 1.7e-19 70.1 0.1 2.9e-19 69.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON96769.1 - 3e-14 53.2 0.0 4.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96769.1 - 4.8e-10 39.2 0.0 0.001 18.6 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EON96769.1 - 8.7e-10 39.1 0.0 2.9e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON96769.1 - 1.6e-09 38.1 0.0 3e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON96769.1 - 3e-06 27.5 0.0 1.3e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96769.1 - 2e-05 23.8 0.0 0.00049 19.2 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EON96769.1 - 0.00021 20.3 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EON96769.1 - 0.00099 19.1 0.0 0.0034 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON96769.1 - 0.005 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EON96769.1 - 0.007 15.8 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EON96769.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EON96769.1 - 0.05 12.7 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EON96769.1 - 0.14 11.3 0.1 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Glyco_hydro_3 PF00933.16 EON96770.1 - 7.9e-84 281.1 0.0 1.1e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON96770.1 - 1.4e-39 135.9 1.0 2.1e-38 132.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON96770.1 - 9.9e-25 86.2 0.2 1.7e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain TMF_TATA_bd PF12325.3 EON96771.1 - 0.94 9.2 14.3 0.052 13.2 2.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EON96771.1 - 1.8 6.3 7.1 2.4 5.9 4.0 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 EON96771.1 - 8.8 4.6 14.8 0.11 10.9 1.1 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family adh_short PF00106.20 EON96772.1 - 2.8e-18 66.3 0.2 3.5e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96772.1 - 4.5e-06 26.5 0.0 5.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96772.1 - 0.0001 22.0 0.1 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Sld5 PF05916.6 EON96774.1 - 5.1e-08 33.1 0.5 8.9e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 GINS complex protein F-box PF00646.28 EON96776.1 - 2.1e-06 27.2 1.6 4.3e-06 26.2 1.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EON96776.1 - 0.00019 21.0 1.5 0.00052 19.6 1.0 1.8 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 EON96778.1 - 1.4e-23 83.6 0.2 2.5e-23 82.8 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON96778.1 - 4.5e-13 49.2 0.1 7.1e-13 48.6 0.1 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON96778.1 - 1.9e-09 37.6 0.0 2.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON96778.1 - 3.5e-05 23.3 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON96778.1 - 9.5e-05 22.4 0.1 0.00015 21.7 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EON96778.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EON96778.1 - 0.031 13.1 0.2 0.05 12.4 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3842 PF12953.2 EON96778.1 - 0.17 12.0 1.9 0.41 10.7 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3842) Aldolase_II PF00596.16 EON96779.1 - 1.6e-37 128.9 0.0 3.1e-37 127.9 0.0 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.17 EON96780.1 - 2.9e-133 444.6 0.1 3.4e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EON96780.1 - 0.022 13.4 0.0 0.048 12.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FAD_binding_3 PF01494.14 EON96781.1 - 5.4e-79 265.8 0.0 6.7e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EON96781.1 - 1.1e-32 112.9 0.0 2.1e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EON96781.1 - 6.7e-06 26.1 0.0 8.8e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON96781.1 - 8.5e-06 26.0 0.0 0.0039 17.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON96781.1 - 0.0001 20.8 0.2 0.00018 20.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EON96781.1 - 0.00055 19.9 0.1 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON96781.1 - 0.00066 19.8 0.1 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON96781.1 - 0.0015 17.5 0.9 0.0024 16.8 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein XdhC_C PF13478.1 EON96781.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 XdhC Rossmann domain GIDA PF01134.17 EON96781.1 - 0.0039 16.1 0.1 0.0075 15.1 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EON96781.1 - 0.0046 15.8 0.0 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EON96781.1 - 0.0048 15.5 0.0 0.0077 14.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 EON96781.1 - 0.0086 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 EON96781.1 - 0.0093 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 EON96781.1 - 0.011 15.3 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EON96781.1 - 0.012 14.4 0.1 0.022 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EON96781.1 - 0.023 13.7 0.3 0.048 12.7 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EON96781.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EON96781.1 - 0.044 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EON96781.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CDK2AP PF09806.4 EON96782.1 - 1.1 9.4 10.3 1.6 8.9 7.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Calreticulin PF00262.13 EON96783.1 - 1.2e-159 530.9 19.5 1.7e-159 530.3 13.5 1.2 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.5 EON96783.1 - 0.086 13.5 0.6 0.75 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) NAD_binding_4 PF07993.7 EON96784.1 - 4.7e-13 48.6 0.5 4.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EON96784.1 - 3.1e-11 43.1 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON96784.1 - 1.2e-10 40.6 0.1 2.4e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EON96784.1 - 4.8e-08 33.2 0.7 5e-07 29.9 0.5 2.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EON96784.1 - 1.1e-05 24.7 0.2 1.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EON96784.1 - 0.00052 19.7 0.3 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.10 EON96784.1 - 0.0067 15.3 0.1 0.012 14.5 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EON96784.1 - 0.026 14.4 3.0 0.64 9.9 2.1 2.7 2 1 0 2 2 2 0 short chain dehydrogenase ATP11 PF06644.6 EON96785.1 - 1.7e-88 296.6 0.0 2e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein TMCO5 PF14992.1 EON96785.1 - 0.052 12.6 0.2 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family SAB PF04382.8 EON96785.1 - 0.084 12.5 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 SAB domain TPR_16 PF13432.1 EON96786.1 - 2.6e-06 27.9 0.2 0.0025 18.4 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 EON96786.1 - 0.00013 21.8 9.5 0.57 9.8 0.1 3.6 3 1 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EON96786.1 - 0.022 15.3 0.1 39 5.2 0.0 5.4 6 2 2 8 8 8 0 Tetratricopeptide repeat Prefoldin PF02996.12 EON96787.1 - 4.7e-24 84.3 0.4 6.1e-24 83.9 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Cep57_MT_bd PF06657.8 EON96787.1 - 0.0015 18.3 0.3 0.0031 17.4 0.2 1.5 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Fzo_mitofusin PF04799.8 EON96787.1 - 0.0089 15.4 0.4 3.1 7.1 0.1 2.1 2 0 0 2 2 2 2 fzo-like conserved region COG2 PF06148.6 EON96787.1 - 0.017 14.9 0.3 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dam1 PF08653.5 EON96787.1 - 0.026 14.2 0.1 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Sec2p PF06428.6 EON96787.1 - 0.035 13.9 3.2 0.1 12.4 0.4 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p CCDC155 PF14662.1 EON96787.1 - 0.1 12.1 3.1 0.088 12.3 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 TMF_TATA_bd PF12325.3 EON96787.1 - 0.12 12.0 1.8 1.4 8.6 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EON96787.1 - 0.16 11.5 2.9 0.41 10.2 0.8 1.9 2 0 0 2 2 2 0 IncA protein SF-assemblin PF06705.6 EON96787.1 - 0.19 10.8 1.3 1 8.4 0.0 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin Tektin PF03148.9 EON96787.1 - 0.23 9.9 1.2 2.8 6.3 0.1 2.0 2 0 0 2 2 2 0 Tektin family KH_1 PF00013.24 EON96789.1 - 1.8e-39 133.1 6.7 1.4e-16 59.8 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EON96789.1 - 6.3e-28 95.9 12.5 2.7e-11 42.8 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EON96789.1 - 1.1e-12 47.3 5.4 0.0029 17.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EON96789.1 - 5.4e-05 22.7 2.4 0.97 9.1 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EON96789.1 - 0.011 15.5 9.1 0.81 9.5 0.1 3.6 4 0 0 4 4 4 0 NusA-like KH domain Lipase_3 PF01764.20 EON96790.1 - 7.4e-30 103.4 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EON96790.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EON96790.1 - 0.0021 17.4 0.2 0.02 14.2 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EON96790.1 - 0.0027 17.6 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EON96790.1 - 0.012 15.7 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EON96790.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EON96790.1 - 0.061 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.9 EON96790.1 - 0.23 10.6 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) BTB PF00651.26 EON96791.1 - 0.0031 17.4 0.1 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Dynamin_M PF01031.15 EON96792.1 - 9.4e-115 382.4 0.0 3.2e-114 380.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EON96792.1 - 3.7e-55 186.2 0.4 1e-54 184.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EON96792.1 - 2e-31 107.7 1.7 7.1e-31 105.9 1.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EON96792.1 - 0.00068 19.5 0.2 0.004 17.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EON96792.1 - 0.015 15.7 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Cu-oxidase_3 PF07732.10 EON96793.1 - 9.6e-43 144.6 0.9 9.6e-43 144.6 0.6 3.2 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EON96793.1 - 1.4e-38 131.5 0.7 8.2e-33 112.8 0.0 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EON96793.1 - 1.3e-27 96.6 0.0 3e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase DUF1752 PF08550.5 EON96794.1 - 9.9e-12 44.2 2.4 2.2e-11 43.1 1.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4611 PF15387.1 EON96794.1 - 0.0087 16.1 3.7 0.027 14.6 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Spt5_N PF11942.3 EON96794.1 - 0.29 11.7 10.9 2.5 8.7 2.2 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BUD22 PF09073.5 EON96794.1 - 0.53 9.2 9.2 0.91 8.5 6.4 1.4 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.1 EON96794.1 - 8.7 6.7 10.9 4.7 7.5 0.3 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 EON96795.1 - 2.7e-13 50.3 0.1 3.3e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96795.1 - 1.5e-07 31.3 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON96795.1 - 0.00069 19.2 0.0 0.02 14.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EON96795.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EON96795.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Glyco_hydro_15 PF00723.16 EON96796.1 - 5.8e-51 173.4 0.0 2.6e-48 164.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 SBDS PF01172.13 EON96797.1 - 3.3e-26 90.9 0.8 3.8e-26 90.7 0.6 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3340 PF11818.3 EON96797.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) RNA_ligase PF09414.5 EON96798.1 - 7.1e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 RNA ligase RWD PF05773.17 EON96799.1 - 2.7e-16 59.4 1.0 3e-16 59.3 0.1 1.5 2 0 0 2 2 2 1 RWD domain U79_P34 PF03064.11 EON96799.1 - 0.32 10.4 2.1 1.4 8.3 0.2 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 PMT PF02366.13 EON96800.1 - 4.3e-79 265.3 16.3 7.4e-79 264.5 11.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EON96800.1 - 9.5e-21 74.1 4.1 8.5e-18 64.5 0.3 2.1 1 1 1 2 2 2 2 MIR domain Fascin PF06268.8 EON96800.1 - 0.12 12.4 0.1 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Fascin domain p450 PF00067.17 EON96801.1 - 2.5e-72 243.8 0.0 4.2e-72 243.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 VWA_2 PF13519.1 EON96802.1 - 4.1e-14 53.0 0.0 5.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EON96802.1 - 1.2e-08 34.8 0.5 1.7e-08 34.4 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EON96802.1 - 1.1e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EON96802.1 - 0.00045 19.5 1.5 0.0016 17.8 1.1 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif DNA_pol3_a_NII PF11490.3 EON96802.1 - 0.14 11.7 3.7 0.13 11.8 1.4 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF243 PF03103.12 EON96802.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Pkinase PF00069.20 EON96803.1 - 2.8e-66 223.3 0.0 4e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96803.1 - 9.3e-39 133.0 0.0 1.3e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON96803.1 - 1.8e-10 40.2 0.0 5e-09 35.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like POLO_box PF00659.13 EON96803.1 - 1.6e-07 31.1 0.1 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EON96803.1 - 0.00052 19.1 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CBF PF03914.12 EON96804.1 - 2.2e-48 163.8 0.0 7.1e-48 162.1 0.0 2.0 1 0 0 1 1 1 1 CBF/Mak21 family BUD22 PF09073.5 EON96804.1 - 8.3e-05 21.8 19.0 8.3e-05 21.8 13.2 2.7 3 0 0 3 3 3 1 BUD22 DUF2178 PF09946.4 EON96804.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Nbl1_Borealin_N PF10444.4 EON96805.1 - 2.2e-22 78.2 5.1 3e-22 77.7 3.6 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Peptidase_S10 PF00450.17 EON96806.1 - 2.7e-16 59.7 0.0 3e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase tRNA-synt_2b PF00587.20 EON96807.1 - 5.4e-34 117.2 0.0 7.1e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EON96807.1 - 4.6e-09 36.1 0.0 7.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain TPR_12 PF13424.1 EON96808.1 - 6.7e-11 41.9 4.6 0.00022 21.0 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EON96808.1 - 1.2e-08 34.2 4.5 0.0025 17.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EON96808.1 - 5.7e-08 32.9 14.0 0.00042 20.5 1.6 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EON96808.1 - 6.2e-07 28.7 4.5 0.0015 18.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EON96808.1 - 3.2e-06 26.5 0.1 0.00051 19.6 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON96808.1 - 4.3e-06 27.2 19.4 0.25 12.0 0.0 4.9 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EON96808.1 - 1.1e-05 24.9 3.6 0.1 12.2 0.0 4.7 2 2 2 5 5 5 3 TPR repeat Apc3 PF12895.2 EON96808.1 - 0.00022 21.2 1.1 0.2 11.7 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EON96808.1 - 0.00032 20.1 0.1 0.035 13.7 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EON96808.1 - 0.00092 19.0 3.0 0.9 9.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EON96808.1 - 0.0012 19.3 22.9 0.024 15.2 0.1 6.0 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EON96808.1 - 0.015 15.1 13.3 0.092 12.6 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EON96808.1 - 0.018 15.1 0.0 62 4.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EON96808.1 - 3.1 8.4 11.4 79 4.0 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Phage_Mu_F PF04233.9 EON96809.1 - 0.67 10.5 4.8 3.3 8.2 1.8 2.3 2 0 0 2 2 2 0 Phage Mu protein F like protein LCD1 PF09798.4 EON96809.1 - 7.2 4.4 8.7 9.4 4.0 6.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Choline_kinase PF01633.15 EON96810.1 - 8.9e-54 182.2 0.0 5.1e-53 179.7 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EON96810.1 - 5.7e-12 45.8 0.5 5.7e-12 45.8 0.3 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EON96810.1 - 0.00048 19.3 0.0 0.0019 17.4 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EON96810.1 - 0.054 12.1 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DNA_Packaging_2 PF11123.3 EON96810.1 - 0.088 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA packaging protein LRR_6 PF13516.1 EON96811.1 - 2.6e-12 45.4 11.6 0.0014 18.4 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 EON96811.1 - 1.2e-09 37.5 13.4 0.00066 19.2 0.0 5.5 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EON96811.1 - 2.7e-06 26.6 6.4 3.5 8.0 0.1 6.2 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 EON96811.1 - 6e-05 22.7 10.5 0.64 9.8 0.0 4.6 3 3 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EON96811.1 - 0.0013 18.6 4.6 80 4.1 0.1 6.2 6 0 0 6 6 6 0 Leucine rich repeat LETM1 PF07766.8 EON96811.1 - 0.061 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 LETM1-like protein V-ATPase_C PF03223.10 EON96812.1 - 1.2e-116 389.6 0.0 1.4e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EON96812.1 - 0.012 15.8 0.8 0.034 14.4 0.1 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain RRM_1 PF00076.17 EON96813.1 - 1.2e-42 143.3 0.1 3.5e-21 74.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON96813.1 - 1.5e-31 108.1 0.0 1.4e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON96813.1 - 2.8e-16 59.1 0.0 2.3e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_PEP_C PF04513.7 EON96815.1 - 1.9e-05 24.5 6.0 0.0024 17.6 0.7 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EON96815.1 - 0.15 12.3 5.1 0.14 12.3 0.5 2.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PhageMin_Tail PF10145.4 EON96815.1 - 0.23 11.0 1.4 0.38 10.3 0.9 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein CENP-K PF11802.3 EON96816.1 - 3.3e-12 46.2 0.5 8.8e-06 25.1 1.1 2.2 2 0 0 2 2 2 2 Centromere-associated protein K SpoU_sub_bind PF08032.7 EON96816.1 - 0.0096 16.0 0.3 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding HECT PF00632.20 EON96816.1 - 0.036 13.2 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) MitMem_reg PF13012.1 EON96816.1 - 0.067 13.2 3.2 0.2 11.7 1.7 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Peptidase_C58 PF03543.9 EON96816.1 - 0.17 11.3 6.5 0.64 9.4 0.2 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Sipho_Gp157 PF05565.6 EON96816.1 - 0.41 10.2 8.8 0.95 9.0 4.6 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 zf-H2C2_2 PF13465.1 EON96817.1 - 1.7e-07 31.1 8.8 3.5e-06 27.0 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EON96817.1 - 1.6e-05 24.8 4.1 0.0006 19.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EON96817.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EON96817.1 - 0.36 11.0 4.0 4.3 7.5 0.3 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CPL PF08144.6 EON96818.1 - 3.2e-21 75.7 0.1 8.4e-20 71.1 0.0 3.2 4 0 0 4 4 4 1 CPL (NUC119) domain DUF3206 PF11472.3 EON96818.1 - 0.046 13.4 0.0 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3206) DUF3049 PF11250.3 EON96818.1 - 0.12 12.1 0.2 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) TraH_2 PF06871.6 EON96818.1 - 1.5 8.2 7.0 0.25 10.7 0.1 2.3 2 0 0 2 2 2 0 TraH_2 Proteasome PF00227.21 EON96819.1 - 1.5e-38 131.9 0.0 1.7e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SNARE PF05739.14 EON96820.1 - 1.7e-09 37.2 2.0 1.7e-09 37.2 1.4 3.4 4 0 0 4 4 4 1 SNARE domain La PF05383.12 EON96821.1 - 2.9e-16 59.0 0.1 5.3e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 La domain Pyr_redox_3 PF13738.1 EON96822.1 - 2.6e-19 70.1 0.0 5.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON96822.1 - 2e-10 39.4 0.3 6.3e-09 34.5 0.1 2.7 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EON96822.1 - 2.2e-08 33.9 0.0 8.5e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON96822.1 - 3.6e-05 23.7 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON96822.1 - 0.00038 19.4 0.0 0.052 12.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMN_dh PF01070.13 EON96823.1 - 5.2e-115 384.1 0.0 6.7e-115 383.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EON96823.1 - 3.7e-06 26.3 0.7 5.9e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EON96823.1 - 5.2e-05 22.3 0.2 8.3e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EON96823.1 - 8.7e-05 21.7 0.2 0.075 12.1 0.2 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EON96823.1 - 0.00058 18.8 0.9 0.0011 17.9 0.2 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.16 EON96823.1 - 0.0068 15.4 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EON96823.1 - 0.0083 15.4 0.1 0.073 12.3 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ABC_tran PF00005.22 EON96824.1 - 2.5e-34 118.5 0.0 3.8e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EON96824.1 - 4e-14 51.8 5.4 4e-14 51.8 3.7 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EON96824.1 - 7.7e-14 52.3 10.1 0.00034 20.6 0.1 4.6 3 2 2 5 5 4 4 AAA domain SMC_N PF02463.14 EON96824.1 - 2.4e-12 46.5 1.0 0.00025 20.3 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EON96824.1 - 9.1e-09 34.8 0.5 1.1 8.1 0.0 4.4 5 0 0 5 5 5 3 AAA ATPase domain AAA_17 PF13207.1 EON96824.1 - 1.9e-06 28.6 0.3 0.034 14.9 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EON96824.1 - 1e-05 25.8 0.4 0.28 11.5 0.0 3.1 4 1 0 4 4 2 2 AAA domain AAA PF00004.24 EON96824.1 - 1.6e-05 25.0 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EON96824.1 - 3.8e-05 23.1 0.2 0.041 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4 PF00037.22 EON96824.1 - 5.5e-05 22.5 2.7 5.5e-05 22.5 1.9 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_22 PF13401.1 EON96824.1 - 5.9e-05 23.2 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EON96824.1 - 0.00049 19.3 2.5 0.9 8.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EON96824.1 - 0.00055 20.0 0.5 0.27 11.4 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 EON96824.1 - 0.00057 19.9 0.0 0.45 10.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.17 EON96824.1 - 0.00067 19.1 2.1 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EON96824.1 - 0.0011 18.6 0.1 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EON96824.1 - 0.0011 18.7 1.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EON96824.1 - 0.0014 18.3 1.2 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain VirE PF05272.6 EON96824.1 - 0.0016 17.9 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_21 PF14697.1 EON96824.1 - 0.0018 18.0 10.9 0.0036 17.1 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 EON96824.1 - 0.0021 17.4 0.0 0.99 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EON96824.1 - 0.0026 17.6 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 EON96824.1 - 0.0057 16.4 11.1 0.0073 16.1 1.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EON96824.1 - 0.0066 15.8 0.3 4 6.7 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase AAA_5 PF07728.9 EON96824.1 - 0.0082 15.8 0.5 0.3 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_7 PF12838.2 EON96824.1 - 0.0089 16.3 7.6 0.01 16.1 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.1 EON96824.1 - 0.0095 16.2 4.5 0.045 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EON96824.1 - 0.011 14.5 0.0 0.52 9.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.1 EON96824.1 - 0.022 13.2 0.0 0.022 13.2 0.0 2.7 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.10 EON96824.1 - 0.023 13.4 0.0 0.13 10.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Miro PF08477.8 EON96824.1 - 0.03 14.8 0.2 2.2 8.7 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_28 PF13521.1 EON96824.1 - 0.058 13.3 0.7 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EON96824.1 - 0.076 12.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EON96824.1 - 0.078 13.0 8.3 0.22 11.5 1.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EON96824.1 - 0.081 13.6 0.1 0.081 13.6 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MukB PF04310.7 EON96824.1 - 0.1 11.9 1.0 6.4 6.0 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal AAA_24 PF13479.1 EON96824.1 - 0.11 12.0 0.7 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EON96824.1 - 0.13 11.9 1.5 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EON96824.1 - 0.13 12.1 1.3 15 5.4 0.0 3.3 2 2 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 EON96824.1 - 0.13 11.6 3.6 0.34 10.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.2 EON96824.1 - 0.36 10.8 11.8 0.19 11.7 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 EON96824.1 - 0.65 9.8 15.7 0.032 14.0 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EON96824.1 - 2.7 8.3 14.4 0.072 13.3 1.6 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Methyltransf_16 PF10294.4 EON96825.1 - 0.0061 16.0 0.0 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase ATP_sub_h PF10775.4 EON96826.1 - 3.3e-25 87.5 0.9 4.8e-25 87.0 0.6 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EON96826.1 - 0.059 13.2 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Tuberculin PF12198.3 EON96826.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Theoretical tuberculin protein Formyl_trans_N PF00551.14 EON96827.1 - 2.1e-38 131.7 0.0 2.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Lum_binding PF00677.12 EON96828.1 - 5.6e-40 135.1 0.6 6.8e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Methyltransf_11 PF08241.7 EON96829.1 - 2.3e-12 47.2 0.0 6.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON96829.1 - 2.4e-06 27.3 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON96829.1 - 0.0025 18.2 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96829.1 - 0.0037 17.8 0.0 0.02 15.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96829.1 - 0.021 13.9 0.0 0.052 12.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EON96829.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EON96829.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Pkinase PF00069.20 EON96830.1 - 5.8e-67 225.5 0.0 7.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96830.1 - 2.8e-31 108.5 0.0 3.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EON96830.1 - 0.0019 18.7 0.4 0.0043 17.5 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EON96830.1 - 0.04 12.8 0.0 0.098 11.5 0.0 1.6 1 1 0 2 2 2 0 Kinase-like APH PF01636.18 EON96830.1 - 0.065 12.9 0.2 0.8 9.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF515 PF04415.7 EON96830.1 - 0.83 7.8 2.9 1.3 7.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) E1-E2_ATPase PF00122.15 EON96832.1 - 5.5e-62 208.8 7.0 2e-61 206.9 3.8 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EON96832.1 - 7.5e-45 152.6 8.9 7.5e-45 152.6 4.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EON96832.1 - 2.6e-32 112.9 0.0 8.1e-31 108.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON96832.1 - 7.4e-23 80.3 0.0 1.4e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EON96832.1 - 2.6e-18 65.2 0.0 6.5e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EON96832.1 - 1.2e-17 64.7 0.0 4e-17 63.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON96832.1 - 2.4e-08 33.8 0.8 6.6e-06 25.8 0.6 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EON96832.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 EON96833.1 - 1.4e-55 187.3 0.0 2.1e-32 112.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EON96833.1 - 2e-29 102.8 21.1 1.4e-19 70.6 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EON96833.1 - 2.3e-08 33.5 1.6 0.024 13.8 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EON96833.1 - 8.3e-08 31.8 0.6 0.0086 15.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EON96833.1 - 9.9e-08 31.4 0.4 0.011 15.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EON96833.1 - 1e-07 32.1 0.3 3.6 7.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_23 PF13476.1 EON96833.1 - 2.4e-07 31.2 0.1 0.0013 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EON96833.1 - 1.8e-06 28.1 0.8 0.43 10.4 0.1 4.2 3 1 0 3 3 3 2 AAA domain T2SE PF00437.15 EON96833.1 - 3.6e-05 22.7 0.4 0.031 13.1 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF87 PF01935.12 EON96833.1 - 4.9e-05 23.2 4.7 0.0053 16.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EON96833.1 - 0.00029 21.6 0.2 0.21 12.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EON96833.1 - 0.00035 19.7 0.1 0.63 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EON96833.1 - 0.00044 20.1 0.1 0.71 9.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EON96833.1 - 0.00051 19.5 1.0 2.5 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EON96833.1 - 0.00076 19.5 5.3 1.3 9.0 0.1 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EON96833.1 - 0.0033 17.3 0.0 5.6 6.8 0.0 3.8 4 0 0 4 4 3 0 AAA domain Miro PF08477.8 EON96833.1 - 0.0054 17.2 0.1 4.7 7.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EON96833.1 - 0.0091 16.3 1.5 2.3 8.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EON96833.1 - 0.0096 15.0 0.6 0.86 8.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EON96833.1 - 0.015 14.9 1.1 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 EON96833.1 - 0.025 13.3 0.2 0.66 8.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EON96833.1 - 0.031 13.7 0.0 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EON96833.1 - 0.046 12.7 0.3 0.72 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EON96833.1 - 0.054 12.3 1.7 0.95 8.2 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Sigma54_activat PF00158.21 EON96833.1 - 0.068 12.6 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EON96833.1 - 0.12 11.5 0.1 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EON96833.1 - 0.53 9.9 1.8 24 4.6 0.0 2.7 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 EON96834.1 - 2.7e-35 121.6 0.0 5.4e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EON96834.1 - 4.2e-16 59.1 10.8 5.5e-16 58.7 7.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EON96834.1 - 4.4e-06 26.8 0.0 0.0048 16.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EON96834.1 - 2.5e-05 23.6 0.0 0.00013 21.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EON96834.1 - 0.0028 16.8 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EON96834.1 - 0.0031 18.3 0.2 0.0077 17.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EON96834.1 - 0.008 15.6 0.2 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.15 EON96834.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.1 EON96834.1 - 0.032 14.1 0.2 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EON96834.1 - 0.034 14.4 0.1 0.066 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EON96834.1 - 0.035 13.2 0.1 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EON96834.1 - 0.063 12.6 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EON96834.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain HSP20 PF00011.16 EON96835.1 - 1.5e-18 66.5 0.7 1.5e-13 50.4 0.0 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family DUF4432 PF14486.1 EON96835.1 - 0.029 12.9 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Ribosomal_L36e PF01158.13 EON96836.1 - 1.7e-40 136.9 5.0 1.9e-40 136.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EON96836.1 - 0.01 14.9 0.1 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 LemA family SUI1 PF01253.17 EON96837.1 - 4.8e-23 80.7 0.7 1e-22 79.6 0.5 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EON96837.1 - 0.0011 18.8 0.1 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV tRNA_edit PF04073.10 EON96837.1 - 0.17 11.7 2.0 0.33 10.7 1.4 1.5 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain SpoIIE PF07228.7 EON96838.1 - 9.9e-12 44.9 0.1 4.3e-11 42.8 0.1 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EON96838.1 - 7.5e-11 41.8 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EON96838.1 - 4.7e-07 29.4 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.17 EON96839.1 - 5.8e-16 57.8 0.4 1e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON96839.1 - 1.1e-10 41.2 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON96839.1 - 0.00096 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EON96839.1 - 0.054 13.0 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PAT1 PF09770.4 EON96839.1 - 6 4.9 6.6 8.6 4.4 4.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ras PF00071.17 EON96840.1 - 3.3e-49 166.3 0.0 4e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON96840.1 - 2.5e-15 57.0 0.0 4.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON96840.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EON96840.1 - 0.00045 20.3 0.1 0.0025 17.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EON96840.1 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EON96840.1 - 0.024 13.9 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EON96840.1 - 0.035 12.8 2.1 0.6 8.7 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EON96840.1 - 0.061 13.4 0.2 0.23 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EON96840.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EON96840.1 - 0.077 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EON96840.1 - 0.14 11.2 0.3 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 KaiC UPF0079 PF02367.12 EON96840.1 - 0.14 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Cytochrom_C1 PF02167.10 EON96841.1 - 3.2e-81 272.1 0.0 3.9e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EON96841.1 - 0.008 16.3 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III 4HBT PF03061.17 EON96842.1 - 2.1e-10 40.6 0.0 4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily MIP-T3 PF10243.4 EON96843.1 - 0.00086 17.9 42.5 0.0013 17.2 29.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 EON96843.1 - 0.013 15.0 1.8 0.013 15.0 1.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3439 PF11921.3 EON96843.1 - 0.046 13.4 11.4 0.1 12.3 7.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EON96843.1 - 0.061 11.3 12.5 0.085 10.8 8.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NST1 PF13945.1 EON96843.1 - 0.26 11.3 36.3 0.82 9.7 18.3 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF1168 PF06658.7 EON96843.1 - 1.4 8.3 49.6 0.8 9.2 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF1510 PF07423.6 EON96843.1 - 5.4 6.3 42.1 3.3 7.0 19.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) YL1 PF05764.8 EON96843.1 - 5.6 6.4 39.6 5.6 6.5 5.2 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Sporozoite_P67 PF05642.6 EON96843.1 - 7 4.3 27.9 0.03 12.2 3.4 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4647 PF15504.1 EON96843.1 - 7.4 5.3 33.6 10 4.8 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SUFU_C PF12470.3 EON96843.1 - 7.7 6.0 14.7 0.28 10.7 5.1 1.9 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain adh_short PF00106.20 EON96844.1 - 6.2e-26 91.2 0.0 7.6e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96844.1 - 2.2e-25 89.8 0.0 2.7e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96844.1 - 6.2e-11 42.2 0.0 7.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EON96844.1 - 0.018 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EON96844.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RNase_PH PF01138.16 EON96845.1 - 5.7e-11 42.8 0.0 1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EON96845.1 - 0.0043 16.9 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-Nse PF11789.3 EON96846.1 - 0.047 13.2 0.5 0.18 11.3 0.0 2.3 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit NAD_kinase PF01513.16 EON96847.1 - 4.2e-71 239.0 0.0 5.5e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase ABC_membrane PF00664.18 EON96848.1 - 2.2e-74 250.3 37.4 3.9e-43 147.8 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EON96848.1 - 6.3e-64 214.3 0.0 8e-32 110.3 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EON96848.1 - 1.7e-12 47.9 0.1 0.028 14.3 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EON96848.1 - 3.7e-12 45.9 10.0 0.0002 20.6 2.8 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EON96848.1 - 3.1e-09 35.9 0.3 0.0039 15.8 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EON96848.1 - 4.6e-09 36.4 0.4 0.0044 17.1 0.0 4.5 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EON96848.1 - 1.5e-08 34.0 1.4 0.00027 20.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EON96848.1 - 1.5e-07 32.2 0.3 0.023 15.5 0.3 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EON96848.1 - 2.8e-07 30.6 0.2 0.0068 16.4 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EON96848.1 - 4.9e-07 29.0 0.0 0.034 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EON96848.1 - 7.9e-07 29.6 0.2 0.015 15.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EON96848.1 - 5.3e-06 26.1 0.6 0.19 11.3 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EON96848.1 - 3.2e-05 23.4 0.8 0.34 10.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EON96848.1 - 0.00013 21.7 2.4 0.26 11.2 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EON96848.1 - 0.0005 19.7 0.1 0.22 11.3 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EON96848.1 - 0.00092 19.1 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EON96848.1 - 0.00099 19.4 0.0 2.5 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EON96848.1 - 0.0011 18.1 0.1 0.059 12.4 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EON96848.1 - 0.0014 18.1 0.1 0.13 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 EON96848.1 - 0.0026 17.4 0.0 2.8 7.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EON96848.1 - 0.0028 17.1 0.0 3.5 7.0 0.0 2.8 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EON96848.1 - 0.0057 16.3 0.3 1.4 8.5 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EON96848.1 - 0.0071 16.2 0.1 1.9 8.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain DUF3987 PF13148.1 EON96848.1 - 0.0076 14.8 0.6 0.13 10.7 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.12 EON96848.1 - 0.012 15.2 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EON96848.1 - 0.014 14.4 0.0 1.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 EON96848.1 - 0.023 14.1 0.1 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 EON96848.1 - 0.038 13.8 0.3 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 EON96848.1 - 0.043 13.7 0.0 8 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EON96848.1 - 0.095 13.2 0.0 16 5.9 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein DUF3094 PF11293.3 EON96848.1 - 1.1 8.8 3.5 18 4.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) PRMT5 PF05185.11 EON96849.1 - 3.3e-11 42.7 0.0 4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EON96849.1 - 8.5e-11 41.6 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EON96849.1 - 4.1e-10 39.2 0.0 6.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EON96849.1 - 7.7e-08 32.9 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON96849.1 - 2e-07 31.0 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON96849.1 - 4.2e-07 30.3 0.0 8.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON96849.1 - 4.9e-06 26.8 0.1 1.4e-05 25.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EON96849.1 - 9.7e-06 24.4 0.1 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EON96849.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EON96849.1 - 0.00051 19.1 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EON96849.1 - 0.00095 18.5 0.1 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EON96849.1 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EON96849.1 - 0.025 14.2 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EON96849.1 - 0.061 12.4 0.5 0.14 11.2 0.2 1.7 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family HAT PF02184.11 EON96850.1 - 1.4e-30 104.6 61.8 3.1e-15 55.6 1.6 13.8 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EON96850.1 - 4.6e-27 92.0 19.1 0.00024 21.4 0.1 11.6 8 2 4 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.1 EON96850.1 - 1.1e-24 86.5 0.2 9.9e-07 29.0 0.0 7.5 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EON96850.1 - 1.2e-21 76.8 11.1 0.00057 20.4 0.1 7.9 9 1 1 10 10 8 5 Tetratricopeptide repeat Suf PF05843.9 EON96850.1 - 2.4e-15 57.0 17.2 0.0045 16.7 1.1 6.5 3 1 1 5 5 5 5 Suppressor of forked protein (Suf) TPR_12 PF13424.1 EON96850.1 - 2.3e-09 37.0 13.4 0.017 15.0 0.0 8.2 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 EON96850.1 - 7.4e-08 31.9 4.5 0.077 12.6 0.1 6.2 4 1 4 8 8 8 2 TPR repeat TPR_6 PF13174.1 EON96850.1 - 9.4e-08 32.0 14.3 1.4 9.5 0.0 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EON96850.1 - 1.4e-07 30.8 16.4 0.17 10.8 0.5 6.2 3 1 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EON96850.1 - 1.8e-06 27.4 21.0 0.24 11.3 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EON96850.1 - 1.3e-05 24.8 17.5 0.36 10.6 0.7 7.4 5 2 1 7 7 7 1 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 EON96850.1 - 1.5e-05 24.4 9.9 3.8 7.5 0.0 7.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EON96850.1 - 3.5e-05 23.2 0.7 26 4.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EON96850.1 - 6e-05 22.8 0.1 0.55 10.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EON96850.1 - 0.00054 19.9 2.8 17 5.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EON96850.1 - 0.0086 15.6 6.9 3.4 7.4 0.0 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EON96850.1 - 0.025 13.4 0.2 0.025 13.4 0.1 6.1 3 3 1 6 6 6 0 NRDE-2, necessary for RNA interference Fis1_TPR_C PF14853.1 EON96850.1 - 0.11 12.4 10.3 24 4.8 0.1 6.1 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Oxysterol_BP PF01237.13 EON96851.1 - 2.8e-77 259.5 0.0 3.4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RNB PF00773.14 EON96852.1 - 9.2e-48 163.1 0.0 2.7e-30 105.7 0.0 2.8 2 1 1 3 3 3 2 RNB domain Fer2_3 PF13085.1 EON96853.1 - 1.5e-33 114.9 0.0 2.4e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 EON96853.1 - 2.4e-09 37.0 4.4 2.4e-09 37.0 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EON96853.1 - 2.7e-09 37.2 6.3 2.7e-09 37.2 4.4 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EON96853.1 - 1.6e-05 25.1 6.7 6e-05 23.3 1.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EON96853.1 - 0.00011 21.9 3.9 0.00011 21.9 2.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EON96853.1 - 0.0002 21.5 4.3 0.033 14.4 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EON96853.1 - 0.0017 18.0 2.8 0.0026 17.4 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EON96853.1 - 0.0096 16.2 5.5 0.0096 16.2 3.8 2.5 2 1 1 3 3 3 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EON96853.1 - 0.037 14.4 3.7 0.053 13.9 0.5 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 EON96853.1 - 2.6 8.7 6.7 0.86 10.2 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Cyclin_N PF00134.18 EON96854.1 - 4.8e-11 42.3 0.3 2.4e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EON96854.1 - 0.00068 19.5 0.0 0.042 13.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain Nup84_Nup100 PF04121.8 EON96855.1 - 1.6e-67 227.7 0.8 1.3e-65 221.4 0.6 3.0 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Filament PF00038.16 EON96856.1 - 0.0028 17.1 87.7 0.12 11.7 1.9 6.8 3 1 1 6 6 6 5 Intermediate filament protein IncA PF04156.9 EON96856.1 - 0.013 15.0 2.6 0.013 15.0 1.8 6.9 4 2 1 5 5 5 0 IncA protein YbjQ_1 PF01906.12 EON96856.1 - 0.045 14.1 0.5 0.92 9.9 0.1 3.3 2 0 0 2 2 2 0 Putative heavy-metal-binding tRNA-synt_1_2 PF13603.1 EON96856.1 - 0.083 12.1 0.0 0.27 10.4 0.0 1.9 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CopC PF04234.7 EON96856.1 - 3.7 8.2 5.8 7.9 7.1 0.2 3.6 3 0 0 3 3 3 0 CopC domain Myb_DNA-bind_6 PF13921.1 EON96857.1 - 6.1e-05 23.0 0.5 0.00012 22.0 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EON96857.1 - 0.011 15.7 0.6 0.029 14.4 0.4 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain HTH_28 PF13518.1 EON96857.1 - 0.08 12.9 0.4 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain zf-GRF PF06839.7 EON96858.1 - 1.7e-07 31.0 4.0 2.8e-07 30.3 2.7 1.4 1 0 0 1 1 1 1 GRF zinc finger SIR2 PF02146.12 EON96859.1 - 2.9e-25 89.0 0.0 9.3e-25 87.3 0.0 1.8 1 1 0 1 1 1 1 Sir2 family DUF4349 PF14257.1 EON96859.1 - 0.58 9.3 3.3 0.39 9.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Sugar_tr PF00083.19 EON96860.1 - 5.9e-31 107.5 29.4 1.1e-18 67.0 7.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON96860.1 - 7.3e-22 77.5 20.8 1.1e-13 50.6 8.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Microtub_bind PF13931.1 EON96861.1 - 3.4 7.7 15.2 0.39 10.8 6.8 2.2 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding PTPA PF03095.10 EON96862.1 - 2.5e-112 374.9 0.0 3e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.27 EON96863.1 - 2.6e-26 90.4 10.6 6.9e-07 28.9 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EON96863.1 - 1.8e-05 24.5 0.3 0.069 12.8 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EON96863.1 - 0.00012 20.4 0.3 0.0039 15.3 0.0 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EON96863.1 - 0.005 15.6 0.0 0.011 14.5 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region DUF1513 PF07433.6 EON96863.1 - 0.025 13.5 0.0 0.66 8.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.1 EON96863.1 - 0.043 14.1 0.0 22 5.4 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Not3 PF04065.10 EON96864.1 - 0.068 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Mod_r PF07200.8 EON96866.1 - 2e-09 37.5 6.4 4.2e-09 36.4 4.4 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.7 EON96866.1 - 2.4 6.5 6.8 2.7 6.2 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERCC4 PF02732.10 EON96867.1 - 3.6e-32 111.0 0.1 5.3e-32 110.5 0.1 1.2 1 0 0 1 1 1 1 ERCC4 domain SH3_9 PF14604.1 EON96868.1 - 4.2e-31 106.2 4.2 1.9e-15 56.1 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EON96868.1 - 3.3e-27 93.6 7.7 7.1e-14 50.9 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EON96868.1 - 6.7e-18 63.9 0.0 5.3e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EON96868.1 - 1.7e-11 44.1 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Asp_protease PF09668.5 EON96868.1 - 0.32 10.5 0.0 0.6 9.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Ferritin_2 PF13668.1 EON96869.1 - 2.9e-28 98.5 3.7 4.7e-25 88.1 1.0 2.8 3 0 0 3 3 3 2 Ferritin-like domain Pkinase PF00069.20 EON96870.1 - 2.9e-71 239.6 0.0 3.7e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96870.1 - 3.1e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EON96870.1 - 4.6e-14 52.6 2.2 1.1e-13 51.4 1.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EON96870.1 - 4.3e-10 39.0 0.0 8.9e-10 37.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EON96870.1 - 0.00025 20.8 0.1 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Kdo PF06293.9 EON96870.1 - 0.0089 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EON96870.1 - 0.036 13.3 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EON96870.1 - 0.038 13.5 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EON96870.1 - 0.066 12.9 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fe_hyd_lg_C PF02906.9 EON96871.1 - 2.7e-13 49.8 0.1 3.9e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Sec10 PF07393.6 EON96872.1 - 5.5e-224 745.4 1.6 7.5e-224 745.0 1.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 LAM_C PF12544.3 EON96873.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EON96873.1 - 0.0009 19.4 0.0 0.0033 17.6 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EON96873.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain TLV_coat PF00429.14 EON96874.1 - 0.0098 14.3 3.2 0.011 14.2 2.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Pkinase PF00069.20 EON96875.1 - 5.9e-69 232.1 0.0 1.2e-68 231.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON96875.1 - 3.1e-37 128.0 0.0 5.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON96875.1 - 6.6e-07 28.5 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EON96875.1 - 0.0022 17.1 0.0 0.098 11.7 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EON96875.1 - 0.0031 17.2 0.0 0.0082 15.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EON96875.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF566 PF04484.7 EON96876.1 - 2.7 7.4 7.2 3.9 6.8 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) 6PGD PF00393.14 EON96877.1 - 2.1e-133 444.0 0.0 2.6e-133 443.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EON96877.1 - 3e-51 173.4 0.0 4.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EON96877.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EON96877.1 - 0.12 12.7 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent C2 PF00168.25 EON96879.1 - 1.3e-72 239.6 2.4 7.6e-20 70.5 0.0 5.7 6 0 0 6 6 6 5 C2 domain DUF2404 PF10296.4 EON96879.1 - 0.072 13.2 0.0 0.37 10.9 0.0 2.2 3 0 0 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) TUG-UBL1 PF11470.3 EON96880.1 - 3.2e-24 84.6 0.0 7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 EON96880.1 - 0.0039 16.9 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain INO80_Ies4 PF08193.6 EON96880.1 - 0.2 11.5 8.2 0.13 12.2 2.0 2.4 2 0 0 2 2 2 0 INO80 complex subunit Ies4 DUF605 PF04652.11 EON96880.1 - 2.2 7.6 20.0 0.027 13.8 5.9 2.1 2 0 0 2 2 2 0 Vta1 like ACC_epsilon PF13822.1 EON96883.1 - 0.25 11.7 4.2 0.33 11.3 2.9 1.2 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit WD40 PF00400.27 EON96884.1 - 2.8e-51 169.6 21.1 2.9e-10 39.6 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EON96884.1 - 6.3e-15 54.1 1.3 1.3e-14 53.1 0.9 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EON96884.1 - 0.032 13.9 0.0 1.4 8.6 0.0 3.1 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EON96884.1 - 0.055 12.5 0.1 13 4.7 0.0 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EON96884.1 - 0.11 11.2 0.2 11 4.5 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like CRF PF00473.12 EON96885.1 - 0.15 12.1 0.7 0.15 12.1 0.5 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family U1snRNP70_N PF12220.3 EON96885.1 - 1.7 9.0 9.4 0.2 12.0 1.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PBP1_TM PF14812.1 EON96885.1 - 7.4 6.9 9.4 2.8 8.3 2.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.8 EON96886.1 - 2.3e-131 438.4 0.0 2.3e-131 438.4 0.0 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EON96886.1 - 0.015 14.0 0.6 0.026 13.2 0.4 1.3 1 0 0 1 1 1 0 Nitrogen permease regulator 2 NfeD PF01957.13 EON96888.1 - 0.29 11.2 2.0 9.2 6.3 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF1761 PF08570.5 EON96888.1 - 0.69 9.9 6.7 0.081 12.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Med16 PF11635.3 EON96889.1 - 8.8e-52 176.0 0.1 1.1e-51 175.6 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 LSM PF01423.17 EON96891.1 - 2e-19 68.8 0.1 2.3e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EON96891.1 - 0.00017 21.4 0.1 0.00021 21.1 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EON96891.1 - 0.066 13.0 0.1 0.077 12.8 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SpoA PF01052.15 EON96891.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) IceA2 PF05862.6 EON96891.1 - 0.12 12.0 0.9 0.15 11.7 0.1 1.6 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein CHCH PF06747.8 EON96893.1 - 2.5e-05 24.0 2.6 3.5e-05 23.5 1.8 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EON96893.1 - 0.0033 17.4 2.3 0.056 13.4 1.9 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EON96893.1 - 0.11 12.5 3.6 0.95 9.5 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) TAFII55_N PF04658.8 EON96894.1 - 3.3e-49 166.4 0.2 6e-49 165.6 0.2 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region PCNA_N PF00705.13 EON96895.1 - 5.1e-57 190.8 3.4 1e-56 189.9 2.4 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EON96895.1 - 3.2e-50 169.3 0.0 6.6e-50 168.3 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EON96895.1 - 1.6e-10 40.5 0.0 2e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EON96895.1 - 1.9e-07 30.1 0.4 1.1e-05 24.4 0.3 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EON96895.1 - 0.00012 21.1 0.1 0.00043 19.3 0.1 1.9 1 1 1 2 2 2 1 Hus1-like protein Cmc1 PF08583.5 EON96896.1 - 1.4e-17 63.1 4.3 1.6e-17 62.9 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_9 PF13371.1 EON96896.1 - 0.069 13.0 0.1 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat NDUF_B7 PF05676.8 EON96896.1 - 0.097 12.0 1.2 0.15 11.5 0.8 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.6 EON96896.1 - 1 9.5 4.8 1.6 8.8 1.1 2.1 1 1 1 2 2 2 0 GCK domain HATPase_c_3 PF13589.1 EON96897.1 - 1.2e-12 47.6 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EON96897.1 - 1.2e-09 37.8 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EON96897.1 - 9.7e-09 34.7 0.0 2.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF651 PF04895.7 EON96897.1 - 0.17 11.5 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF651) Pro_isomerase PF00160.16 EON96898.1 - 1.1e-50 171.9 0.2 2.5e-50 170.6 0.2 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EON96898.1 - 1e-13 50.5 0.2 1.4e-07 31.0 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat DAHP_synth_1 PF00793.15 EON96899.1 - 7.1e-97 323.3 0.0 8.4e-97 323.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Spore_YtfJ PF09579.5 EON96900.1 - 7.2 6.5 7.2 21 5.0 4.5 2.0 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) RRN3 PF05327.6 EON96901.1 - 1.7e-167 557.9 0.0 1.7e-167 557.9 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.14 EON96901.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-CCCH PF00642.19 EON96902.1 - 7.1e-09 35.1 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EON96902.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON96902.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 EON96902.1 - 0.72 9.6 5.2 0.53 10.1 0.2 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Tachystatin_B PF11478.3 EON96902.1 - 5.4 6.8 10.3 0.25 11.0 1.2 2.7 2 1 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B CBFD_NFYB_HMF PF00808.18 EON96903.1 - 4.3e-26 90.7 1.3 7.8e-26 89.9 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EON96903.1 - 3.4e-07 30.2 0.1 5.8e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EON96903.1 - 0.0013 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EON96903.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EON96903.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF4653 PF15546.1 EON96903.1 - 0.14 11.4 3.9 0.1 11.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) Trp_oprn_chp PF09534.5 EON96905.1 - 0.83 9.2 8.7 5.6 6.5 0.8 4.0 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.11 EON96906.1 - 2e-20 72.8 47.7 2.7e-20 72.3 32.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.7 EON96907.1 - 7.3e-13 48.2 0.0 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EON96907.1 - 6e-10 38.7 0.3 1.3e-08 34.4 0.2 2.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HobA PF12163.3 EON96907.1 - 0.03 13.6 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA replication regulator LIM PF00412.17 EON96908.1 - 3e-21 75.2 30.5 3.6e-08 33.3 3.9 3.6 4 0 0 4 4 4 3 LIM domain DNA_pol_B_palm PF14792.1 EON96909.1 - 8.5e-34 115.9 0.0 1.5e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EON96909.1 - 6.2e-22 77.0 0.0 2.2e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EON96909.1 - 7.2e-19 67.0 0.2 1.4e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EON96909.1 - 4.3e-17 62.0 0.0 1.9e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EON96909.1 - 0.011 16.0 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Methyltransf_11 PF08241.7 EON96910.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96910.1 - 9.7e-05 22.9 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON96910.1 - 0.00012 21.7 0.0 0.0002 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON96910.1 - 0.00014 21.8 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON96910.1 - 0.00066 18.7 0.0 0.0099 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EON96910.1 - 0.00091 19.6 0.0 0.0026 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EON96910.1 - 0.001 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EON96910.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EON96910.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EON96910.1 - 0.034 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EON96910.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EON96910.1 - 0.056 12.9 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RNA_pol_Rpb4 PF03874.11 EON96911.1 - 3.9e-18 65.5 6.1 2.6e-17 62.9 4.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF89 PF01937.14 EON96911.1 - 0.0096 14.7 0.1 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF964 PF06133.6 EON96911.1 - 0.018 15.0 3.4 0.02 14.8 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF964) Tht1 PF04163.7 EON96911.1 - 0.023 13.1 1.3 0.025 12.9 0.9 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Pectate_lyase_2 PF06917.7 EON96911.1 - 0.072 11.3 0.1 0.089 11.0 0.1 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase CorA PF01544.13 EON96911.1 - 0.29 10.1 3.6 0.37 9.7 2.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein dsDNA_bind PF01984.15 EON96911.1 - 0.45 10.5 4.4 3.4 7.7 3.1 2.2 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Fungal_trans_2 PF11951.3 EON96912.1 - 9.7e-50 169.2 5.1 1.9e-41 141.9 0.2 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Dus PF01207.12 EON96914.1 - 1.2e-25 90.0 0.0 2.6e-25 88.9 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Sel1 PF08238.7 EON96915.1 - 1.1e-37 127.5 29.9 1.2e-05 25.8 0.1 7.7 8 0 0 8 8 8 7 Sel1 repeat DMRL_synthase PF00885.14 EON96916.1 - 3.2e-45 153.3 0.1 2.1e-27 95.5 0.1 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase HLH PF00010.21 EON96917.1 - 8.7e-13 47.7 0.0 3.2e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 EON96917.1 - 0.00047 20.2 0.3 0.28 11.3 0.1 2.4 2 0 0 2 2 2 2 Patatin phospholipase Trs65 PF12735.2 EON96918.1 - 2e-75 253.9 0.0 2.7e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Glutaredoxin PF00462.19 EON96919.1 - 6e-19 67.7 0.0 1.9e-17 62.9 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EON96919.1 - 1.4e-14 53.6 0.0 4.9e-14 51.8 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EON96919.1 - 0.0025 17.5 0.0 0.26 11.1 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_8 PF13905.1 EON96919.1 - 0.0051 16.9 0.0 0.79 9.8 0.0 2.7 1 1 1 2 2 2 1 Thioredoxin-like ArsC PF03960.10 EON96919.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 ArsC family Disulph_isomer PF06491.6 EON96919.1 - 0.085 12.7 0.1 8.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Disulphide isomerase HyaE PF07449.6 EON96919.1 - 0.11 12.4 0.0 0.92 9.4 0.0 2.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE AMP-binding PF00501.23 EON96920.1 - 1.5e-87 293.6 0.0 2.9e-87 292.7 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON96920.1 - 2.3e-14 54.0 0.4 5.8e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FF PF01846.14 EON96921.1 - 2.2e-55 184.4 12.7 1.2e-14 53.9 0.1 7.0 6 1 0 6 6 6 6 FF domain WW PF00397.21 EON96921.1 - 8.7e-19 67.0 11.5 7.4e-10 38.5 0.9 2.6 2 0 0 2 2 2 2 WW domain V_ATPase_I PF01496.14 EON96921.1 - 3.7 5.2 7.0 7.9 4.1 4.8 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vezatin PF12632.2 EON96922.1 - 7.2e-60 202.1 0.0 1.2e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes TPR_MLP1_2 PF07926.7 EON96922.1 - 0.12 12.1 3.3 0.18 11.5 0.2 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1656 PF07869.7 EON96922.1 - 0.8 9.5 4.5 1.8 8.3 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Ammonium_transp PF00909.16 EON96925.1 - 3.2e-117 391.3 30.3 3.7e-117 391.1 21.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Proteasome PF00227.21 EON96926.1 - 8.2e-28 96.9 0.1 2.4e-27 95.4 0.2 1.7 2 1 0 2 2 2 1 Proteasome subunit Rad60-SLD PF11976.3 EON96927.1 - 2.6e-19 68.6 0.1 3.1e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EON96927.1 - 1.7e-09 36.8 0.0 2.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EON96927.1 - 0.079 12.7 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) SNF2_N PF00176.18 EON96928.1 - 7.2e-65 218.7 0.0 1.3e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EON96928.1 - 4.5e-26 90.2 3.2 8.4e-15 54.1 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EON96928.1 - 5.4e-15 55.0 0.3 2e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain POR PF01558.13 EON96928.1 - 0.066 13.1 0.3 0.46 10.3 0.0 2.4 3 0 0 3 3 3 0 Pyruvate ferredoxin/flavodoxin oxidoreductase YTH PF04146.10 EON96929.1 - 1.9e-57 192.7 0.0 2.6e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 EON96929.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON96929.1 - 0.09 12.4 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prp31_C PF09785.4 EON96930.1 - 3.8e-41 140.4 1.1 8.2e-41 139.3 0.7 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EON96930.1 - 1.2e-39 134.9 0.3 2.3e-39 134.0 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EON96930.1 - 4.9e-21 74.2 0.1 1.1e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Glyco_hydro_18 PF00704.23 EON96931.1 - 1.1e-85 288.0 8.7 1.3e-85 287.9 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PI3_PI4_kinase PF00454.22 EON96933.1 - 5.4e-40 137.3 0.0 1.9e-39 135.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EON96933.1 - 1.4e-22 79.7 0.1 3.6e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Acetate_kinase PF00871.12 EON96934.1 - 4.1e-90 302.1 0.0 5.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 EON96934.1 - 0.026 13.3 0.1 0.041 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) APS_kinase PF01583.15 EON96935.1 - 5.3e-72 240.6 0.0 8.5e-72 239.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EON96935.1 - 1e-06 28.7 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON96935.1 - 2.8e-06 28.1 0.0 4.6e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON96935.1 - 5.3e-05 23.5 0.0 8.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EON96935.1 - 0.00022 20.5 0.0 0.00026 20.3 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EON96935.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EON96935.1 - 0.042 13.3 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EON96935.1 - 0.045 13.7 0.3 0.28 11.1 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.1 EON96935.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EON96935.1 - 0.07 12.1 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 EON96935.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin BTB PF00651.26 EON96936.1 - 1.1e-09 38.2 0.1 1.4e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain dUTPase PF00692.14 EON96937.1 - 8.4e-45 151.3 0.0 9.6e-45 151.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EON96937.1 - 0.012 14.0 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 14-3-3 PF00244.15 EON96938.1 - 2.7e-114 380.1 1.9 3.2e-114 379.9 1.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EON96938.1 - 0.014 15.2 0.2 7.1 6.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF837 PF05769.6 EON96938.1 - 0.039 13.4 0.3 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4240 PF14024.1 EON96938.1 - 0.096 12.5 0.1 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) DUF4395 PF14340.1 EON96939.1 - 0.022 14.8 1.1 0.022 14.8 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) MdcE PF06833.6 EON96939.1 - 0.1 11.7 0.3 0.14 11.3 0.2 1.1 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF4149 PF13664.1 EON96939.1 - 0.12 12.4 8.1 0.024 14.6 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) WD40 PF00400.27 EON96940.1 - 5e-09 35.6 0.7 6.9e-07 28.9 0.2 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2415 PF10313.4 EON96940.1 - 0.0017 18.0 0.0 0.0041 16.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Fungal_trans PF04082.13 EON96941.1 - 3.7e-17 62.0 0.2 5.4e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ALIX_LYPXL_bnd PF13949.1 EON96941.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Patatin PF01734.17 EON96942.1 - 4.8e-11 42.9 0.0 8.5e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase GPI-anchored PF10342.4 EON96943.1 - 1e-18 67.5 1.6 1e-18 67.5 1.1 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hex_IIIa PF02455.11 EON96943.1 - 0.12 10.9 7.7 0.17 10.5 5.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MDFI PF15316.1 EON96943.1 - 1.3 8.9 7.6 1.9 8.4 5.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor RAP1 PF07218.6 EON96943.1 - 6.6 4.6 23.9 7.7 4.4 16.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.6 EON96943.1 - 7.2 4.8 13.6 8.6 4.5 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.6 EON96943.1 - 7.7 5.6 9.3 9.5 5.3 6.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 EON96943.1 - 8.3 4.5 25.0 10 4.2 17.3 1.1 1 0 0 1 1 1 0 Transmembrane protein PGM_PMM_I PF02878.11 EON96944.1 - 5.8e-19 67.9 0.3 1.6e-08 34.1 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EON96944.1 - 5.7e-14 52.3 0.2 4.1e-13 49.5 0.0 2.5 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EON96944.1 - 2.7e-11 43.2 0.2 1e-10 41.4 0.2 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EON96944.1 - 0.0012 18.8 0.1 0.0091 16.0 0.0 2.4 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III HTH_31 PF13560.1 EON96944.1 - 0.071 13.3 0.4 1 9.5 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Chitin_synth_2 PF03142.10 EON96945.1 - 1.5e-295 980.5 0.2 1.5e-295 980.5 0.2 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EON96945.1 - 2.5e-18 66.4 4.6 1.5e-17 63.9 3.2 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON96945.1 - 8.3e-16 58.4 0.0 1.1e-14 54.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EON96945.1 - 2.5e-13 49.6 0.2 1.7e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EON96945.1 - 9.8e-05 21.7 0.0 0.0042 16.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EON96945.1 - 0.011 15.4 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Dus PF01207.12 EON96946.1 - 6e-42 143.5 0.1 1.3e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ligase_CoA PF00549.14 EON96947.1 - 3.5e-36 124.1 5.5 1.5e-19 70.0 0.3 2.4 2 0 0 2 2 2 2 CoA-ligase Succ_CoA_lig PF13607.1 EON96947.1 - 3.9e-13 49.1 0.5 2.4e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.14 EON96947.1 - 8.2e-13 48.6 1.2 2.3e-12 47.2 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 EON96947.1 - 0.00058 19.2 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain HTH_Tnp_ISL3 PF13542.1 EON96947.1 - 0.11 11.7 0.1 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ELMO_CED12 PF04727.8 EON96949.1 - 2.6e-52 176.8 0.0 5.9e-52 175.6 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EON96949.1 - 9.6e-05 22.1 0.2 0.0067 16.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) peroxidase PF00141.18 EON96950.1 - 7.4e-49 166.3 0.0 1.6e-48 165.1 0.0 1.5 2 0 0 2 2 2 1 Peroxidase DUF4366 PF14283.1 EON96950.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Xpo1 PF08389.7 EON96951.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Exportin 1-like protein Arginosuc_synth PF00764.14 EON96952.1 - 2e-142 474.8 0.0 2.4e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase TRP PF06011.7 EON96953.1 - 1.3e-135 452.4 19.0 1.6e-135 452.0 13.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EON96953.1 - 5.5e-37 126.9 2.8 9.9e-37 126.1 1.9 1.4 1 0 0 1 1 1 1 ML-like domain Ribonuc_L-PSP PF01042.16 EON96954.1 - 1.4e-40 137.8 0.2 1.5e-40 137.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Exo_endo_phos PF03372.18 EON96955.1 - 2.1e-14 54.0 0.1 2.2e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 EON96955.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Glyco_hydro_63 PF03200.11 EON96956.1 - 1.4e-177 592.0 0.0 2.2e-177 591.4 0.0 1.2 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EON96956.1 - 0.026 13.2 0.2 0.054 12.1 0.1 1.5 1 1 0 1 1 1 0 Trehalase MFS_1 PF07690.11 EON96957.1 - 1.2e-10 40.6 45.6 2.4e-10 39.6 31.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2263 PF10021.4 EON96958.1 - 2.1e-17 63.4 0.0 3.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EON96958.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Macro domain Aldo_ket_red PF00248.16 EON96959.1 - 9e-48 162.5 0.0 1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.10 EON96959.1 - 0.00075 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain DIOX_N PF14226.1 EON96961.1 - 7e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EON96961.1 - 7.1e-20 71.1 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.15 EON96962.1 - 1.8e-41 141.1 0.0 4.4e-41 139.9 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Spatacsin_C PF14649.1 EON96963.1 - 5.3 5.8 9.6 0.82 8.4 1.2 2.2 1 1 1 2 2 2 0 Spatacsin C-terminus tRNA-synt_1 PF00133.17 EON96964.1 - 5.4e-40 136.9 0.0 3.7e-28 97.9 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EON96964.1 - 3.6e-18 65.3 0.0 4.6e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EON96964.1 - 1.9e-13 50.4 1.8 4.4e-13 49.2 1.3 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EON96964.1 - 5.8e-07 28.9 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YxiJ PF14176.1 EON96964.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 YxiJ-like protein Transp_cyt_pur PF02133.10 EON96965.1 - 1.3e-23 83.3 9.9 2.4e-19 69.2 5.9 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Cyt-b5 PF00173.23 EON96966.1 - 3.3e-09 36.4 0.0 5.7e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.20 EON96967.1 - 2.5e-27 95.8 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON96967.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON96967.1 - 5.4e-11 42.4 0.0 8.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON96967.1 - 5.7e-07 29.1 0.0 1.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON96967.1 - 0.0054 16.7 0.4 0.049 13.6 0.1 2.3 2 2 0 2 2 2 1 NADH(P)-binding Ldh_1_N PF00056.18 EON96967.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EON96967.1 - 0.032 13.1 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EON96967.1 - 0.12 12.1 0.2 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldo_ket_red PF00248.16 EON96968.1 - 1.5e-57 194.5 0.0 1.7e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupredoxin_1 PF13473.1 EON96969.1 - 0.0063 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain FinO_N PF12602.3 EON96969.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Fertility inhibition protein N terminal Cu_bind_like PF02298.12 EON96969.1 - 0.13 12.0 0.3 0.37 10.6 0.2 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.15 EON96969.1 - 0.14 12.3 1.0 0.31 11.2 0.7 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family MGC-24 PF05283.6 EON96969.1 - 0.4 10.4 12.5 0.094 12.4 6.1 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Ribosomal_S7 PF00177.16 EON96970.1 - 2e-40 137.7 1.0 2.4e-40 137.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_M24 PF00557.19 EON96971.1 - 1.8e-16 60.3 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 HSP70 PF00012.15 EON96972.1 - 1.5e-13 49.5 0.0 4.2e-11 41.4 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein Peptidase_M22 PF00814.20 EON96972.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family BcrAD_BadFG PF01869.15 EON96972.1 - 0.18 11.0 0.4 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Glyco_hydro_10 PF00331.15 EON96973.1 - 3.9e-82 275.8 0.0 4.4e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MFS_1 PF07690.11 EON96974.1 - 1.2e-13 50.5 20.3 1.2e-13 50.5 14.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.8 EON96975.1 - 1.1e-33 116.5 0.0 1.4e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON96975.1 - 4.8e-15 56.0 0.1 6.3e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EON96975.1 - 5.5e-06 25.2 0.0 9.5e-06 24.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EON96975.1 - 6.3e-06 25.7 0.1 3.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EON96975.1 - 9.8e-06 25.5 0.4 2.2e-05 24.4 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON96975.1 - 0.00042 20.0 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EON96975.1 - 0.00069 18.6 0.0 0.0068 15.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EON96975.1 - 0.024 13.5 0.3 0.14 10.9 0.2 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein CmcI PF04989.7 EON96975.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DapB_N PF01113.15 EON96975.1 - 0.078 12.8 0.1 0.21 11.4 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 EON96976.1 - 3.5e-38 131.2 83.9 1.8e-30 105.9 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin PF00091.20 EON96977.1 - 5.6e-69 232.2 0.0 7.9e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EON96977.1 - 1.1e-48 164.4 0.1 1.9e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EON96977.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain DUF1415 PF07209.7 EON96977.1 - 0.1 12.3 0.1 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Ribosomal_S25 PF03297.10 EON96978.1 - 3.4e-40 136.3 4.3 3.7e-40 136.2 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 EON96978.1 - 0.031 13.9 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.7 EON96978.1 - 0.036 13.2 0.1 0.057 12.5 0.1 1.2 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_11 PF08279.7 EON96978.1 - 0.055 13.1 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.1 EON96978.1 - 0.057 12.8 0.1 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EON96978.1 - 0.096 12.4 0.2 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Staphylokinase PF02821.11 EON96978.1 - 0.26 11.0 1.7 0.44 10.3 0.4 1.7 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_4 PF12763.2 EON96979.1 - 1.1e-32 111.8 0.0 3e-12 46.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EON96979.1 - 2.6e-08 33.8 0.0 0.0024 17.9 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain pair UBA PF00627.26 EON96979.1 - 1.1e-06 28.2 0.0 2.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EON96979.1 - 2.2e-05 23.4 0.0 9.9 5.7 0.0 4.9 5 0 0 5 5 5 0 EF hand EF-hand_6 PF13405.1 EON96979.1 - 4.5e-05 22.9 0.1 0.71 9.9 0.0 4.7 5 0 0 5 5 4 1 EF-hand domain Macoilin PF09726.4 EON96979.1 - 9.5e-05 20.8 11.7 9.5e-05 20.8 8.1 1.8 2 0 0 2 2 2 1 Transmembrane protein EF-hand_8 PF13833.1 EON96979.1 - 0.0001 21.8 0.0 0.035 13.7 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair IncA PF04156.9 EON96979.1 - 0.002 17.7 32.4 0.065 12.8 6.7 2.3 1 1 1 2 2 2 2 IncA protein DUF1664 PF07889.7 EON96979.1 - 0.0036 17.0 5.1 0.0036 17.0 3.5 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Rab5-bind PF09311.6 EON96979.1 - 0.0065 16.3 35.5 0.0079 16.1 6.6 3.4 1 1 2 3 3 3 2 Rabaptin-like protein AAA_27 PF13514.1 EON96979.1 - 0.019 12.7 20.9 0.029 12.0 14.5 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 EON96979.1 - 0.031 14.0 36.8 0.31 10.7 15.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EON96979.1 - 0.041 13.7 33.9 0.024 14.5 11.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EON96979.1 - 0.15 9.3 30.4 0.21 8.8 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EON96979.1 - 0.21 9.9 21.9 0.32 9.3 15.2 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EON96979.1 - 0.24 10.0 28.3 0.24 10.0 5.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.7 EON96979.1 - 0.36 8.9 22.0 0.61 8.1 15.2 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FUSC PF04632.7 EON96979.1 - 0.59 8.4 8.0 1.4 7.2 5.6 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.3 EON96979.1 - 0.74 9.5 28.1 3.5 7.3 1.1 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 EON96979.1 - 0.85 7.0 12.3 1.3 6.4 8.5 1.2 1 0 0 1 1 1 0 Prominin Reo_sigmaC PF04582.7 EON96979.1 - 1.5 7.8 10.5 2.8 7.0 1.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 EON96979.1 - 1.8 7.7 34.2 7.4 5.7 11.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EON96979.1 - 2.6 6.9 34.1 3.6 6.5 12.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 EON96979.1 - 4.3 7.1 34.5 5.4 6.7 9.3 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NYD-SP28_assoc PF14775.1 EON96979.1 - 5.8 6.7 7.5 0.91 9.2 2.0 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Mnd1 PF03962.10 EON96979.1 - 6.6 6.3 31.3 3.8 7.1 6.9 2.2 1 1 1 2 2 2 0 Mnd1 family Cluap1 PF10234.4 EON96979.1 - 8.7 5.4 25.8 2.3 7.3 6.3 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 ADIP PF11559.3 EON96979.1 - 10 6.0 40.8 3 7.7 9.3 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Frataxin_Cyay PF01491.11 EON96981.1 - 7.5e-35 119.0 0.0 9e-35 118.7 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain CCDC155 PF14662.1 EON96982.1 - 0.00049 19.7 6.5 0.0012 18.5 4.5 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 HALZ PF02183.13 EON96982.1 - 0.012 15.2 3.2 0.012 15.2 2.2 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 EON96982.1 - 0.12 10.1 1.2 0.16 9.7 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EON96982.1 - 0.2 10.6 6.6 0.42 9.5 4.5 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EON96982.1 - 0.41 10.2 6.8 0.75 9.3 4.7 1.5 1 0 0 1 1 1 0 IncA protein Lzipper-MIP1 PF14389.1 EON96982.1 - 0.45 10.6 7.9 1.1 9.3 5.5 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF342 PF03961.8 EON96982.1 - 0.45 8.8 4.7 0.79 8.0 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LTXXQ PF07813.7 EON96982.1 - 0.83 10.1 10.4 0.041 14.3 2.1 2.4 2 0 0 2 2 2 0 LTXXQ motif family protein DEAD PF00270.24 EON96983.1 - 2.8e-30 105.0 0.1 5.6e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EON96983.1 - 3.1e-22 78.2 0.2 6.6e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON96983.1 - 0.00015 21.6 0.0 0.00015 21.6 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit CENP-X PF09415.5 EON96984.1 - 6e-28 96.4 0.1 1.1e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF688 PF05097.7 EON96984.1 - 0.048 12.6 0.5 0.055 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) PBP1_TM PF14812.1 EON96984.1 - 0.16 12.2 3.2 0.27 11.5 2.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBFD_NFYB_HMF PF00808.18 EON96984.1 - 0.23 11.5 0.8 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acetyltransf_1 PF00583.19 EON96987.1 - 7.5e-07 29.0 0.1 7.1e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON96987.1 - 2.5e-05 24.3 0.0 7.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EON96987.1 - 0.00046 20.7 0.0 1.2 9.6 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF4246 PF14033.1 EON96988.1 - 4.9e-177 589.5 0.0 5.8e-177 589.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EON96988.1 - 0.035 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase IBR PF01485.16 EON96989.1 - 5.9e-13 48.4 6.5 2.7e-11 43.1 1.9 2.3 2 0 0 2 2 2 2 IBR domain PRP21_like_P PF12230.3 EON96989.1 - 0.0098 15.4 4.3 0.013 14.9 3.0 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Asp-B-Hydro_N PF05279.6 EON96989.1 - 0.38 10.5 7.4 0.49 10.2 5.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lar_restr_allev PF14354.1 EON96989.1 - 0.89 9.9 8.9 26 5.2 0.2 3.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-tcix PF14952.1 EON96989.1 - 0.94 8.8 4.4 2 7.8 0.2 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Zn-ribbon_8 PF09723.5 EON96989.1 - 2.5 8.1 7.3 15 5.5 1.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain HAUS6_N PF14661.1 EON96989.1 - 3.8 6.7 10.1 5.5 6.2 7.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Methyltransf_18 PF12847.2 EON96990.1 - 1.7e-11 44.7 0.0 3.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON96990.1 - 2e-07 30.8 0.0 1.2e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON96990.1 - 4.1e-07 29.7 0.0 6.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON96990.1 - 6.9e-07 29.6 0.0 2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EON96990.1 - 8.2e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EON96990.1 - 3e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EON96990.1 - 7.7e-05 23.4 0.0 0.00026 21.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON96990.1 - 9.3e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 EON96990.1 - 0.00024 20.2 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EON96990.1 - 0.00051 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON96990.1 - 0.0023 17.9 0.0 0.0046 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON96990.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EON96990.1 - 0.038 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.6 EON96990.1 - 0.05 12.9 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.14 EON96990.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EON96990.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PIGA PF08288.7 EON96992.1 - 3.7e-45 152.2 3.1 1.5e-44 150.2 0.7 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EON96992.1 - 1.1e-29 103.0 0.0 1.7e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EON96992.1 - 5e-16 58.9 0.6 9e-16 58.0 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EON96992.1 - 3.5e-15 56.3 0.0 7.1e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EON96992.1 - 5.4e-14 52.6 0.0 9.7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EON96992.1 - 9.1e-05 22.3 0.3 0.00015 21.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EON96992.1 - 0.00029 21.0 0.0 0.001 19.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tran_WbsX PF14307.1 EON96992.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase WbsX Mito_carr PF00153.22 EON96993.1 - 1.1e-67 223.8 4.8 2.8e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 EON96994.1 - 9.8e-29 100.0 0.0 1.2e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSDC PF12588.3 EON96995.1 - 1.2e-37 128.6 0.0 4.3e-37 126.8 0.0 1.8 1 1 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EON96995.1 - 3.1e-34 118.0 0.0 4.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EON96995.1 - 0.0011 18.5 0.2 0.56 9.9 0.1 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EON96995.1 - 0.025 14.2 0.0 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme PTS_EIIA_1 PF00358.15 EON96995.1 - 0.084 12.4 0.4 0.26 10.8 0.3 1.8 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GFA PF04828.9 EON96996.1 - 9.5e-14 51.1 0.0 1.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EON96996.1 - 0.0042 16.7 0.1 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.7 EON96996.1 - 0.035 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UNC-93 PF05978.11 EON96997.1 - 4.9e-07 29.3 3.5 1.5e-06 27.8 2.4 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.6 EON96997.1 - 0.029 14.2 1.5 0.094 12.6 0.1 2.6 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain ComJ PF11033.3 EON96997.1 - 0.097 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Competence protein J (ComJ) Peptidase_S15 PF02129.13 EON96998.1 - 4.4e-50 170.6 0.3 5.8e-50 170.2 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EON96998.1 - 1.1e-40 139.8 0.0 2.6e-40 138.6 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EON96998.1 - 2.5e-15 57.0 0.2 5.5e-15 55.8 0.1 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON96998.1 - 2.3e-09 37.1 0.0 9.8e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EON96998.1 - 2.3e-07 30.2 0.4 2.2e-06 27.0 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EON96998.1 - 0.00054 19.5 0.1 0.0042 16.6 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON96998.1 - 0.0087 15.8 0.3 0.027 14.3 0.1 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EON96998.1 - 0.014 14.6 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family PrmA PF06325.8 EON96999.1 - 1.4e-11 44.0 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EON96999.1 - 8.3e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON96999.1 - 1.1e-10 42.0 0.0 3.9e-10 40.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON96999.1 - 1.2e-10 41.7 0.0 3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON96999.1 - 1.2e-08 35.0 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON96999.1 - 1.1e-07 31.4 0.1 1.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EON96999.1 - 5.8e-07 29.8 0.0 1.7e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON96999.1 - 7.9e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EON96999.1 - 1.6e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 EON96999.1 - 3.9e-05 22.7 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EON96999.1 - 8.3e-05 22.9 0.0 0.00022 21.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.11 EON96999.1 - 0.00028 20.5 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 EON96999.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EON96999.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EON96999.1 - 0.0038 15.9 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.1 EON96999.1 - 0.013 16.2 0.0 0.043 14.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.13 EON96999.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EON96999.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EON96999.1 - 0.029 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EON96999.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NAD_binding_8 PF13450.1 EON97000.1 - 4e-13 49.1 0.1 6.9e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EON97000.1 - 5.6e-05 22.2 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EON97000.1 - 8.4e-05 21.8 0.0 8.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EON97000.1 - 0.0019 18.2 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON97000.1 - 0.0094 14.8 0.0 0.023 13.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EON97000.1 - 0.016 15.0 0.0 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EON97000.1 - 0.034 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EON97000.1 - 0.04 13.0 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON97000.1 - 0.049 14.0 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON97000.1 - 0.059 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EON97000.1 - 0.086 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-C2H2 PF00096.21 EON97001.1 - 2.9e-10 39.8 12.1 0.011 16.0 0.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON97001.1 - 5e-07 29.6 14.9 0.0024 18.0 1.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EON97001.1 - 4.7 7.4 7.0 4.7 7.4 0.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rav1p_C PF12234.3 EON97002.1 - 2.1e-127 425.9 2.9 2.2e-121 406.0 1.6 2.0 1 1 1 2 2 2 2 RAVE protein 1 C terminal V-SNARE PF05008.10 EON97003.1 - 1.8e-24 85.6 0.6 1.8e-24 85.6 0.4 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EON97003.1 - 1e-17 63.9 3.1 1e-17 63.9 2.2 2.4 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus AA_permease PF00324.16 EON97004.1 - 1.2e-78 264.5 17.6 1.8e-78 263.9 12.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON97004.1 - 3.5e-22 78.5 23.8 4.2e-22 78.2 16.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF974 PF06159.8 EON97005.1 - 1.5e-81 273.5 0.0 2.1e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 EON97005.1 - 3e-12 45.9 0.0 6.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EON97005.1 - 7.6e-07 28.6 0.4 5.6e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 KH domain MMR_HSR1 PF01926.18 EON97006.1 - 1e-05 25.4 0.0 4.7e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Syd PF07348.7 EON97006.1 - 0.2 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Syd protein (SUKH-2) EPSP_synthase PF00275.15 EON97007.1 - 1.7e-126 422.0 0.0 2.5e-126 421.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EON97007.1 - 3.6e-100 334.2 0.0 5.5e-100 333.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EON97007.1 - 3.3e-64 216.6 0.0 4.9e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EON97007.1 - 7.6e-35 120.1 0.0 5.8e-33 114.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EON97007.1 - 3.4e-25 87.9 0.0 7.5e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EON97007.1 - 1.4e-11 44.6 0.0 5.2e-11 42.7 0.0 1.9 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EON97007.1 - 1.4e-07 31.1 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EON97007.1 - 1.1e-06 29.4 0.0 2.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EON97007.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EON97007.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EON97007.1 - 0.26 11.6 0.0 0.55 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain LEA_2 PF03168.8 EON97008.1 - 3.3e-07 30.6 0.4 0.092 13.1 0.0 4.9 5 0 0 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.3 EON97008.1 - 1e-06 28.7 0.4 1e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ALS_ss_C PF10369.4 EON97009.1 - 1.3e-19 69.6 0.0 3.2e-18 65.2 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EON97009.1 - 2.6e-13 49.1 0.1 5e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EON97009.1 - 7.5e-10 38.4 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EON97009.1 - 0.094 12.4 0.1 16 5.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain RVT_1 PF00078.22 EON97010.1 - 1.7e-06 27.5 0.0 3.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1878 PF08963.5 EON97010.1 - 0.091 12.9 0.0 0.6 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) PPI_Ypi1 PF07491.6 EON97011.1 - 1.6e-23 82.0 2.4 4.4e-23 80.6 1.7 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor GRP PF07172.6 EON97011.1 - 1.1 9.7 9.0 2 8.9 6.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family uDENN PF03456.13 EON97012.1 - 1.5e-17 63.2 0.0 3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 uDENN domain DENN PF02141.16 EON97012.1 - 6.8e-17 61.7 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain GAT PF03127.9 EON97012.1 - 0.1 12.5 0.2 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 GAT domain OTCace PF00185.19 EON97013.1 - 1.4e-40 138.7 0.0 1.7e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EON97013.1 - 1.1e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain XRN_N PF03159.13 EON97014.1 - 1.5e-108 361.6 0.0 1.5e-108 361.6 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF726 PF05277.7 EON97015.1 - 2.8e-83 279.6 0.0 4.3e-65 219.8 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF726) NUC173 PF08161.7 EON97016.1 - 1.1e-79 266.3 0.0 9.1e-77 256.8 0.0 2.7 3 0 0 3 3 3 2 NUC173 domain TraE PF05309.6 EON97016.1 - 0.08 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TraE protein CtaG_Cox11 PF04442.9 EON97017.1 - 1.7e-57 193.4 0.0 2.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 L51_S25_CI-B8 PF05047.11 EON97018.1 - 1.1e-20 73.0 0.0 1.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Uso1_p115_head PF04869.9 EON97019.1 - 4.6e-110 367.2 0.0 9.6e-110 366.1 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EON97019.1 - 2e-07 31.0 46.7 0.00065 19.6 32.4 3.1 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Reo_sigmaC PF04582.7 EON97019.1 - 3.7 6.6 6.6 7.3 5.6 0.4 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein LMBR1 PF04791.11 EON97020.1 - 0.028 13.0 9.6 0.022 13.3 5.6 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Z1 PF10593.4 EON97020.1 - 0.33 10.1 5.3 0.8 8.8 3.7 1.6 1 0 0 1 1 1 0 Z1 domain Herpes_UL6 PF01763.11 EON97020.1 - 0.46 8.6 7.3 0.79 7.8 5.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Tweety PF04906.8 EON97020.1 - 0.95 7.7 3.3 1.4 7.2 2.3 1.1 1 0 0 1 1 1 0 Tweety FemAB PF02388.11 EON97020.1 - 1.7 7.2 8.0 2.9 6.4 5.6 1.3 1 0 0 1 1 1 0 FemAB family V_ATPase_I PF01496.14 EON97020.1 - 3.2 5.4 15.2 0.9 7.3 7.6 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EON97020.1 - 4.3 7.4 16.3 8.1 6.5 6.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Asp-B-Hydro_N PF05279.6 EON97020.1 - 5.2 6.8 16.4 9.7 5.9 11.4 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HAUS6_N PF14661.1 EON97020.1 - 7 5.9 14.6 26 4.0 10.1 2.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Arrestin_N PF00339.24 EON97021.1 - 1.6e-13 50.7 0.0 3.2e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF946 PF06101.6 EON97022.1 - 1.4e-09 36.5 0.6 6.4e-09 34.3 0.1 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 EON97022.1 - 0.1 11.1 0.1 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Med19 PF10278.4 EON97023.1 - 5.5 6.6 7.6 1.9e+02 1.6 5.2 2.5 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 gag-asp_proteas PF13975.1 EON97024.1 - 7.5e-06 25.6 0.1 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EON97024.1 - 2.3e-05 24.7 0.0 3.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Ribosomal_L7Ae PF01248.21 EON97025.1 - 6.8e-25 86.4 0.0 7.7e-25 86.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UcrQ PF02939.11 EON97026.1 - 8.9e-34 115.1 0.7 1.1e-33 114.8 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Vac7 PF12751.2 EON97027.1 - 1.9e-33 115.8 0.1 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 zf-AN1 PF01428.11 EON97028.1 - 1.2e-11 44.2 6.9 1.2e-11 44.2 4.8 1.6 2 0 0 2 2 2 1 AN1-like Zinc finger RrnaAD PF00398.15 EON97029.1 - 1.8e-48 164.8 0.0 3.5e-48 163.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EON97029.1 - 1.4e-11 44.4 0.0 4.1e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON97029.1 - 7.4e-06 26.5 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON97029.1 - 0.00037 19.9 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EON97029.1 - 0.00054 19.1 0.0 0.00085 18.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EON97029.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EON97029.1 - 0.0011 19.3 0.0 0.0046 17.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON97029.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON97029.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EON97029.1 - 0.0082 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EON97029.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EON97029.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DREV PF05219.7 EON97029.1 - 0.056 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CHORD PF04968.7 EON97030.1 - 0.99 9.7 8.0 0.56 10.4 1.2 2.5 1 1 1 2 2 2 0 CHORD Band_7 PF01145.20 EON97031.1 - 3.6e-24 85.6 7.6 4.2e-24 85.4 4.8 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EON97031.1 - 0.012 14.9 2.1 0.017 14.5 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) ADH_N PF08240.7 EON97032.1 - 1.8e-28 98.4 2.1 4.8e-28 97.0 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON97032.1 - 5.3e-19 68.0 0.3 1e-18 67.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EON97032.1 - 0.0042 16.9 1.8 0.089 12.6 1.1 2.3 2 0 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EON97032.1 - 0.028 13.7 0.2 0.053 12.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF676 PF05057.9 EON97033.1 - 4.8e-52 176.4 0.0 6.8e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EON97033.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON97033.1 - 1.9e-06 27.9 0.1 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EON97033.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EON97033.1 - 0.044 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 EON97033.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Ribosomal_L16 PF00252.13 EON97034.1 - 3.9e-31 107.5 0.1 5e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HhH-GPD PF00730.20 EON97035.1 - 2.7e-16 59.7 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EON97035.1 - 6.8e-08 31.7 0.0 1.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Med3 PF11593.3 EON97035.1 - 6.8 5.8 9.9 10 5.2 6.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal APH PF01636.18 EON97036.1 - 3.2e-18 66.3 0.4 5.5e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EON97036.1 - 8.5e-05 21.9 0.2 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 EON97036.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EON97036.1 - 0.08 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase SH3_1 PF00018.23 EON97038.1 - 5e-14 51.4 0.1 1e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON97038.1 - 9.7e-13 47.4 0.1 2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EON97038.1 - 1.8e-10 40.7 0.5 2.7e-10 40.1 0.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EON97038.1 - 1.8e-10 40.1 0.0 3.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 EON97038.1 - 0.013 14.4 0.3 0.02 13.7 0.2 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mito_fiss_reg PF05308.6 EON97038.1 - 1.7 7.9 10.2 5 6.4 7.1 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator dCMP_cyt_deam_1 PF00383.17 EON97039.1 - 1.5e-21 75.9 0.0 5.1e-21 74.2 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EON97039.1 - 0.0072 16.1 4.7 0.032 14.1 0.0 3.1 4 0 0 4 4 4 1 Bd3614-like deaminase DUF2052 PF09747.4 EON97042.1 - 2.7e-34 118.6 7.8 4.6e-34 117.9 5.4 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) MARVEL PF01284.18 EON97043.1 - 5e-05 23.1 17.1 0.00027 20.8 10.6 2.1 1 1 1 2 2 2 2 Membrane-associating domain VIT1 PF01988.14 EON97043.1 - 0.99 8.8 7.5 0.12 11.7 2.3 1.7 1 1 1 2 2 2 0 VIT family Acetyltransf_1 PF00583.19 EON97044.1 - 5.6e-11 42.3 0.1 8.8e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON97044.1 - 2.7e-10 40.2 0.2 4e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EON97044.1 - 0.0022 18.1 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EON97044.1 - 0.017 14.9 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EON97044.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.1 EON97045.1 - 1.1e-07 31.8 0.0 1.2e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON97045.1 - 4.4e-05 23.4 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase SLD3 PF08639.5 EON97046.1 - 0.00057 18.6 0.6 0.00062 18.5 0.4 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 C1_3 PF07649.7 EON97047.1 - 3.1 7.9 6.3 0.35 10.9 0.4 2.5 2 0 0 2 2 2 0 C1-like domain GFA PF04828.9 EON97048.1 - 3.9e-09 36.3 2.4 1.1e-08 34.9 0.0 2.4 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_6 PF12697.2 EON97049.1 - 4.3e-09 36.5 1.3 8.4e-09 35.6 0.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EON97049.1 - 3.4e-07 29.1 0.0 4.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EON97049.1 - 2.3e-05 24.1 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EON97049.1 - 0.0031 16.9 0.0 0.026 13.9 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EON97049.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EON97049.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family UBX PF00789.15 EON97050.1 - 2e-09 37.3 0.0 4.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF3359 PF11839.3 EON97050.1 - 0.27 11.5 11.6 0.44 10.9 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) DUF3123 PF11321.3 EON97050.1 - 6.7 7.0 7.9 0.97 9.7 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) LSM PF01423.17 EON97052.1 - 1.5e-18 66.1 0.1 1.9e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SET PF00856.23 EON97054.1 - 3.8e-20 72.8 3.6 4.8e-20 72.5 0.7 2.6 2 1 0 2 2 2 1 SET domain Zn_clus PF00172.13 EON97057.1 - 0.072 13.0 8.1 0.12 12.2 5.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 EON97058.1 - 7e-28 97.5 3.1 2.3e-26 92.5 2.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S9_N PF02897.10 EON97058.1 - 0.057 12.0 0.0 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Aldo_ket_red PF00248.16 EON97060.1 - 3.7e-48 163.7 0.0 4.3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.18 EON97062.1 - 5.4e-09 36.1 0.0 6.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EON97062.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldedh PF00171.17 EON97063.1 - 2e-76 257.2 0.0 2.2e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.19 EON97064.1 - 9.8e-21 74.0 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Cas_csx3 PF09620.5 EON97065.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_csx3) ADH_N PF08240.7 EON97066.1 - 1e-18 67.0 0.6 4.3e-18 65.0 0.2 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON97066.1 - 1.5e-06 27.7 0.0 4.6e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase HMGL-like PF00682.14 EON97067.1 - 5e-29 101.6 0.2 6.3e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 HMGL-like DUF362 PF04015.7 EON97067.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Myb_DNA-binding PF00249.26 EON97068.1 - 8.2e-06 25.7 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Menin PF05053.8 EON97068.1 - 8.7 4.3 6.3 4.8 5.2 2.7 1.7 1 1 0 1 1 1 0 Menin Tyrosinase PF00264.15 EON97069.1 - 3.3e-35 122.2 2.9 4.9e-35 121.7 2.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DS PF01916.12 EON97070.1 - 1.5e-137 457.6 0.0 1.8e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EON97070.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase MFS_1 PF07690.11 EON97071.1 - 8e-41 139.9 27.2 8e-41 139.9 18.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Tweety PF04906.8 EON97071.1 - 0.26 9.6 3.5 0.57 8.5 2.4 1.6 1 0 0 1 1 1 0 Tweety DUF373 PF04123.8 EON97071.1 - 4.5 6.2 6.8 3.2 6.7 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Amidohydro_4 PF13147.1 EON97072.1 - 4.5e-12 46.5 1.4 1.8e-09 38.0 0.0 3.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EON97072.1 - 4.7e-09 36.3 0.1 1.8e-08 34.4 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EON97072.1 - 1e-05 25.0 0.0 3.2e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EON97072.1 - 1.9e-05 24.3 1.2 0.00026 20.7 0.1 2.8 2 0 0 2 2 2 1 Amidohydrolase SBF PF01758.11 EON97073.1 - 6.1e-25 87.7 9.4 3.2e-15 56.0 1.2 2.1 1 1 1 2 2 2 2 Sodium Bile acid symporter family DUF486 PF04342.7 EON97073.1 - 0.055 13.5 2.4 0.077 13.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF486 Iso_dh PF00180.15 EON97074.1 - 1e-100 337.1 0.0 1.1e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M24 PF00557.19 EON97075.1 - 7.5e-44 149.7 0.1 9.2e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EON97075.1 - 0.00013 21.7 6.6 0.00031 20.5 4.5 1.7 1 0 0 1 1 1 1 MYND finger MutS_V PF00488.16 EON97076.1 - 3.3e-80 268.8 0.1 5.3e-80 268.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EON97076.1 - 5.8e-50 169.9 0.2 1.1e-49 168.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EON97076.1 - 8.1e-33 112.8 0.0 1.7e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EON97076.1 - 1.5e-14 54.2 0.0 4.7e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EON97076.1 - 7e-12 45.3 0.2 1.4e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV FAD_binding_3 PF01494.14 EON97076.1 - 1e-11 44.5 0.0 3.4e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain AAA_23 PF13476.1 EON97076.1 - 0.0045 17.3 0.1 0.0045 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EON97076.1 - 0.018 14.5 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EON97076.1 - 0.038 13.9 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EON97076.1 - 0.34 9.8 0.0 1.5 7.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Herpes_LMP2 PF07415.6 EON97078.1 - 0.99 7.9 3.6 1.8 7.0 2.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein bZIP_1 PF00170.16 EON97079.1 - 0.17 11.8 4.2 0.37 10.7 2.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor Abhydrolase_1 PF00561.15 EON97080.1 - 9e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EON97080.1 - 5.3e-07 29.7 0.0 6.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97080.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3129 PF11327.3 EON97081.1 - 1.4e-57 194.5 14.7 1.4e-57 194.5 10.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) MYEOV2 PF15004.1 EON97081.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Myeloma-overexpressed-like Abhydrolase_5 PF12695.2 EON97082.1 - 1.7e-13 50.5 0.2 3.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON97082.1 - 9.9e-13 48.4 2.6 2e-12 47.5 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97082.1 - 1.3e-07 31.4 0.1 1.7e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON97082.1 - 0.00027 20.7 0.1 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EON97082.1 - 0.0037 16.8 0.2 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EON97082.1 - 0.004 16.6 0.3 0.037 13.4 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.7 EON97082.1 - 0.004 15.9 0.0 0.0055 15.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Cutinase PF01083.17 EON97082.1 - 0.059 13.1 0.4 0.084 12.6 0.3 1.2 1 0 0 1 1 1 0 Cutinase DUF218 PF02698.12 EON97082.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 DUF218 domain Abhydrolase_6 PF12697.2 EON97083.1 - 2e-13 50.7 0.0 2.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97083.1 - 7.6e-09 35.4 0.0 8e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON97083.1 - 0.0019 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EON97083.1 - 0.044 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein gpD PF02925.11 EON97083.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D DUF2048 PF09752.4 EON97083.1 - 0.094 11.5 0.1 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Polyketide_cyc2 PF10604.4 EON97085.1 - 0.0012 19.0 0.1 0.0014 18.7 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport fn3 PF00041.16 EON97086.1 - 4.2e-17 62.0 3.2 8e-08 32.3 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EON97086.1 - 1.2e-09 38.6 3.2 1.8e-09 37.9 0.4 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EON97086.1 - 0.00057 19.7 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TIR_2 PF13676.1 EON97086.1 - 0.019 15.0 0.0 0.06 13.4 0.0 1.9 1 0 0 1 1 1 0 TIR domain Lipase_GDSL_3 PF14606.1 EON97086.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.14 EON97087.1 - 7.2e-22 77.9 0.0 9.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EON97087.1 - 8.6e-06 25.6 0.1 3.4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EON97087.1 - 1.4e-05 25.4 0.0 9.6e-05 22.7 0.0 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON97087.1 - 2.7e-05 23.2 0.0 4.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON97087.1 - 0.00021 21.2 0.0 0.00076 19.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON97087.1 - 0.0018 17.2 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EON97087.1 - 0.0019 17.1 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.9 EON97087.1 - 0.0019 16.7 0.0 0.0028 16.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EON97087.1 - 0.0035 16.4 0.0 0.0079 15.3 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EON97087.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EON97087.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EON97087.1 - 0.048 12.2 0.1 0.29 9.7 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EON97087.1 - 0.053 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NMT_C PF02799.10 EON97088.1 - 5.3e-77 257.5 0.0 8.6e-77 256.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EON97088.1 - 9.7e-72 239.8 0.0 1.8e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EON97088.1 - 6.8e-06 25.9 0.1 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EON97088.1 - 0.042 13.8 0.1 3.3 7.6 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Cornichon PF03311.9 EON97089.1 - 1.8e-54 183.2 9.6 2e-54 183.1 6.7 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 EON97090.1 - 1.8e-41 138.5 8.8 4.1e-11 42.3 0.1 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EON97090.1 - 0.0021 17.7 0.6 0.057 13.1 0.1 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EON97090.1 - 0.0041 15.9 0.1 0.013 14.3 0.1 1.7 1 1 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 EON97090.1 - 0.11 10.5 1.6 19 3.2 0.0 3.2 2 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF3638 PF12340.3 EON97092.1 - 2.4e-94 314.6 0.7 3.7e-70 235.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EON97092.1 - 6.8e-16 57.1 0.1 1.3e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MFS_1 PF07690.11 EON97093.1 - 2.5e-26 92.2 12.3 3e-26 91.9 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 EON97094.1 - 5.4e-66 222.8 0.7 6.6e-66 222.5 0.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 EON97095.1 - 3.7e-20 72.2 0.5 5.9e-20 71.6 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EON97095.1 - 2.5e-08 33.0 8.5 1.5e-07 30.4 5.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EON97096.1 - 9.4e-35 119.8 0.0 1.1e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pec_lyase_C PF00544.14 EON97097.1 - 5.4e-20 71.7 3.8 8.4e-20 71.0 2.6 1.3 1 0 0 1 1 1 1 Pectate lyase CfAFP PF05264.6 EON97097.1 - 0.047 13.4 0.1 0.047 13.4 0.1 2.9 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) ADH_N PF08240.7 EON97098.1 - 3.7e-25 87.8 2.2 5.9e-25 87.1 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON97098.1 - 4.5e-19 68.2 0.0 7.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON97098.1 - 2.5e-08 34.8 0.0 4.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EON97098.1 - 0.0052 15.9 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ran_BP1 PF00638.13 EON97099.1 - 4.2e-50 168.8 1.1 6.8e-50 168.2 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EON97099.1 - 0.00073 19.2 0.2 0.0027 17.4 0.1 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EON97099.1 - 0.017 14.6 0.4 0.029 13.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) GrpB PF04229.9 EON97100.1 - 8.6e-48 162.2 0.0 1e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Phosducin PF02114.11 EON97101.1 - 3.9e-11 42.1 3.5 1.9e-10 39.9 0.1 2.7 2 1 0 2 2 2 1 Phosducin WD40 PF00400.27 EON97102.1 - 4.1e-48 159.5 21.4 9.2e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EON97102.1 - 0.00011 22.0 0.0 0.086 12.5 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Glyco_hydro_18 PF00704.23 EON97103.1 - 1.2e-74 251.8 2.6 1.2e-74 251.8 1.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DNA_ligase_A_M PF01068.16 EON97104.1 - 6.1e-45 153.0 0.0 1.5e-44 151.7 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EON97104.1 - 2.2e-37 128.5 0.0 3.8e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EON97104.1 - 1.2e-16 60.9 0.0 4.8e-16 58.9 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.3 EON97104.1 - 3.3e-05 23.5 0.0 8.1e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.21 EON97104.1 - 5.2e-05 23.3 0.0 0.0043 17.1 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EON97104.1 - 0.019 14.6 0.0 5.3 6.6 0.0 2.6 2 1 1 3 3 3 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EON97104.1 - 0.071 12.7 0.2 20 4.9 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Polysacc_deac_1 PF01522.16 EON97105.1 - 6.3e-12 45.2 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_6 PF12697.2 EON97106.1 - 3.3e-15 56.5 0.0 4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97106.1 - 4.1e-08 33.0 0.0 8.6e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97106.1 - 7e-07 29.0 0.0 9.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EON97106.1 - 0.069 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family Transp_cyt_pur PF02133.10 EON97107.1 - 9.8e-43 146.3 8.2 1.2e-42 146.0 5.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YEATS PF03366.11 EON97108.1 - 6.1e-24 83.5 0.2 1.4e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 YEATS family D-aminoacyl_C PF07908.7 EON97108.1 - 0.063 12.5 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region Peptidase_S10 PF00450.17 EON97109.1 - 2.7e-82 277.1 0.0 3.9e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1082 PF06449.6 EON97110.1 - 0.12 12.2 1.0 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) UPRTase PF14681.1 EON97111.1 - 4.1e-71 238.4 0.0 1.8e-70 236.3 0.0 1.7 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EON97111.1 - 0.00011 21.9 0.0 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 EON97111.1 - 0.043 12.9 0.1 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI P5CR_dimer PF14748.1 EON97111.1 - 0.089 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Amidase PF01425.16 EON97112.1 - 2.3e-75 254.1 0.0 2.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EON97114.1 - 3.9e-13 48.8 19.9 7e-11 41.4 4.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON97114.1 - 2e-11 42.7 4.6 1.4e-10 40.0 3.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TMR-DISM_7TM PF07695.6 EON97114.1 - 0.0095 15.6 4.0 0.0095 15.6 2.7 2.0 2 0 0 2 2 2 1 7TM diverse intracellular signalling Oxidored_FMN PF00724.15 EON97115.1 - 5.6e-95 318.2 0.0 6.5e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EON97115.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme PRAI PF00697.17 EON97115.1 - 0.059 12.9 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF4449 PF14613.1 EON97116.1 - 4e-68 228.4 4.0 4e-68 228.4 2.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 EON97116.1 - 0.00089 19.0 4.7 0.31 10.8 0.0 3.5 1 1 2 3 3 3 2 Prp18 domain FAD_binding_4 PF01565.18 EON97117.1 - 0.00011 21.6 0.7 0.00021 20.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON97117.1 - 0.0072 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_1 PF00232.13 EON97118.1 - 1.8e-46 158.3 0.3 1.1e-37 129.3 0.1 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Cellulase PF00150.13 EON97118.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EON97119.1 - 2.6e-13 49.4 36.7 4.3e-13 48.7 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON97119.1 - 3.2e-11 42.9 8.2 3.2e-11 42.9 5.7 2.7 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Na_Ca_ex PF01699.19 EON97120.1 - 1.1e-38 131.9 33.5 3.5e-20 72.0 9.6 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MutS_V PF00488.16 EON97120.1 - 1.3e-27 96.7 0.1 2.3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EON97120.1 - 2.2e-25 89.6 0.9 4.6e-25 88.6 0.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EON97120.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EON97120.1 - 1.7e-05 24.9 0.0 9.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 MutS domain II RNA_ligase PF09414.5 EON97121.1 - 2.1e-24 86.3 0.0 3.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase RNA_lig_T4_1 PF09511.5 EON97121.1 - 0.02 14.4 0.0 0.052 13.0 0.0 1.6 1 1 0 1 1 1 0 RNA ligase mRNA_cap_enzyme PF01331.14 EON97121.1 - 0.039 13.6 0.0 0.3 10.7 0.0 2.1 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Dynamin_N PF00350.18 EON97122.1 - 1e-28 100.2 0.1 2.8e-28 98.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EON97122.1 - 6e-11 41.6 0.0 1.9e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EON97122.1 - 2e-05 24.4 0.0 6.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EON97122.1 - 0.0039 17.6 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Phe_tRNA-synt_N PF02912.13 EON97122.1 - 0.036 13.7 0.2 0.16 11.6 0.1 2.1 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain AAA_13 PF13166.1 EON97122.1 - 0.23 9.8 2.4 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EON97122.1 - 0.48 10.7 3.4 0.67 10.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain TipAS PF07739.8 EON97122.1 - 1.9 8.8 8.6 4.9 7.5 0.0 3.4 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain ADH_zinc_N PF00107.21 EON97123.1 - 6.7e-26 90.3 0.0 1.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON97123.1 - 5.6e-19 69.2 0.0 1.7e-18 67.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON97123.1 - 1.1e-07 31.5 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PAT1 PF09770.4 EON97123.1 - 0.63 8.2 22.8 0.9 7.7 15.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhyH PF05721.8 EON97124.1 - 1.1e-11 45.2 0.0 1.5e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF917 PF06032.7 EON97125.1 - 9e-92 307.3 0.7 1.4e-91 306.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EON97125.1 - 1.7e-14 53.6 7.6 7.2e-14 51.5 3.0 2.9 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase COesterase PF00135.23 EON97126.1 - 1.7e-76 258.0 0.0 2.2e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EON97126.1 - 4.6e-06 26.3 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyoxalase_2 PF12681.2 EON97127.1 - 3.3e-08 34.1 0.2 0.001 19.6 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EON97127.1 - 4.9e-05 23.3 0.2 0.00022 21.1 0.0 2.1 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1658 PF07871.6 EON97127.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) GMC_oxred_C PF05199.8 EON97128.1 - 9.1e-41 139.5 0.0 1.5e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EON97128.1 - 2.9e-37 128.4 0.0 5.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Beta-lactamase PF00144.19 EON97129.1 - 1.2e-43 149.3 0.1 1.7e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EON97129.1 - 3.3e-11 42.9 0.0 5.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2235 PF09994.4 EON97130.1 - 4e-75 252.7 0.2 5e-73 245.8 0.1 2.8 3 0 0 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) BetaGal_dom4_5 PF13364.1 EON97131.1 - 3.3e-55 185.1 6.2 1.2e-30 105.9 1.9 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EON97131.1 - 4.2e-53 179.4 5.0 4.2e-53 179.4 3.4 1.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EON97131.1 - 6.6e-23 79.9 0.1 1.7e-22 78.5 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.14 EON97131.1 - 1.6e-16 60.5 0.3 8.4e-14 51.6 2.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_2_N PF02837.13 EON97131.1 - 1.8e-05 24.3 0.4 5.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4440 PF14534.1 EON97132.1 - 0.0046 17.1 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) PhyH PF05721.8 EON97133.1 - 0.016 15.2 0.3 0.054 13.5 0.2 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.20 EON97134.1 - 3.1e-22 79.2 0.2 1.5e-21 77.0 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97134.1 - 2.7e-11 43.7 0.3 6.7e-10 39.1 0.1 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EON97134.1 - 5.1e-08 33.1 0.0 8.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EON97134.1 - 5.2e-05 22.9 0.3 0.00024 20.8 0.2 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EON97134.1 - 0.00018 21.1 0.4 0.00047 19.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EON97134.1 - 0.00039 19.7 0.3 0.0013 17.9 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EON97134.1 - 0.0018 17.7 0.1 0.0061 16.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.16 EON97135.1 - 1.8e-31 108.9 0.0 1.3e-23 83.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family FAD_binding_3 PF01494.14 EON97136.1 - 2.9e-15 56.1 1.5 1.8e-13 50.2 1.0 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EON97136.1 - 0.097 11.2 0.0 0.45 9.0 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Aminotran_4 PF01063.14 EON97137.1 - 4e-23 82.1 0.0 5.1e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SLA_LP_auto_ag PF05889.8 EON97137.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Clr5 PF14420.1 EON97138.1 - 2.4e-19 68.9 2.3 6.2e-19 67.6 1.6 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_10 PF13374.1 EON97138.1 - 0.28 11.1 3.5 10 6.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat FTR1 PF03239.9 EON97139.1 - 0.037 12.9 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Raptor_N PF14538.1 EON97139.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF221 PF02714.10 EON97141.1 - 1.7e-98 329.4 16.8 2.5e-98 328.9 11.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EON97141.1 - 1.5e-40 138.3 0.6 1.5e-40 138.3 0.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EON97141.1 - 3.9e-21 75.3 0.5 6.9e-21 74.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EON97141.1 - 0.37 9.3 8.3 0.011 14.3 1.0 1.8 2 0 0 2 2 2 0 Calcium-activated chloride channel Alpha-amylase PF00128.19 EON97142.1 - 7.6e-16 58.3 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EON97142.1 - 0.1 10.3 0.0 0.16 9.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 CFEM PF05730.6 EON97143.1 - 4.8e-14 51.9 10.9 4.8e-14 51.9 7.5 1.6 2 0 0 2 2 2 1 CFEM domain WD40 PF00400.27 EON97144.1 - 1.7e-82 268.5 18.3 2.9e-14 52.3 0.4 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EON97144.1 - 2.2e-09 37.2 0.2 0.0062 16.2 0.0 4.0 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EON97144.1 - 1.3e-06 26.8 1.3 0.054 11.6 0.0 4.1 2 1 0 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 EON97144.1 - 0.00014 21.4 0.1 3.8 7.2 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat NLE PF08154.7 EON97144.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.1 EON97144.1 - 0.013 14.5 0.3 17 4.3 0.0 3.8 2 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 EON97144.1 - 0.093 11.3 0.5 3.3 6.2 0.0 2.9 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Glyco_transf_20 PF00982.16 EON97145.1 - 6e-165 549.2 0.1 8.4e-165 548.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EON97145.1 - 5.7e-45 153.0 0.0 9.2e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EON97145.1 - 0.084 12.3 0.3 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.11 EON97146.1 - 9.9e-14 50.8 38.7 2.6e-07 29.7 15.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily RNA_pol_Rbc25 PF08292.7 EON97146.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 FAA_hydrolase PF01557.13 EON97147.1 - 5.3e-60 202.5 0.0 9e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Colipase PF01114.13 EON97148.1 - 0.02 14.3 3.9 0.036 13.5 2.7 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain PepSY_2 PF13670.1 EON97148.1 - 0.025 14.4 3.8 0.2 11.5 0.4 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain GP38 PF05268.6 EON97148.1 - 0.07 12.5 1.7 0.076 12.4 1.1 1.0 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 GFA PF04828.9 EON97149.1 - 1.1e-11 44.4 2.6 1.1e-11 44.4 1.8 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PhyH PF05721.8 EON97150.1 - 1.7e-13 51.1 0.0 2.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) K_trans PF02705.11 EON97152.1 - 5.1e-179 596.0 18.2 6.1e-179 595.8 12.6 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF485 PF04341.7 EON97152.1 - 8.5 6.1 12.2 4.1 7.1 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function, DUF485 Glyco_hydro_3_C PF01915.17 EON97153.1 - 3e-54 183.9 0.0 4.7e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EON97153.1 - 3e-23 82.2 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EON97153.1 - 1.5e-12 47.2 0.3 3.2e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EON97153.1 - 1.1e-08 34.8 2.3 1.4e-08 34.4 0.0 2.4 3 0 0 3 3 3 1 PA14 domain PA14_2 PF10528.4 EON97154.1 - 2.8e-22 78.7 1.3 5.4e-22 77.8 0.9 1.4 1 0 0 1 1 1 1 GLEYA domain AAA_12 PF13087.1 EON97158.1 - 1.6e-38 132.1 0.1 3.3e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EON97158.1 - 1.7e-23 83.4 0.0 6e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EON97158.1 - 5.2e-07 29.3 0.1 1.6e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EON97158.1 - 1.5e-06 27.4 0.1 0.01 14.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EON97158.1 - 0.00038 20.3 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EON97158.1 - 0.00088 18.9 0.1 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EON97158.1 - 0.0088 16.0 1.9 0.028 14.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EON97158.1 - 0.0089 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 EON97158.1 - 0.029 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 EON97158.1 - 0.08 13.7 1.2 1.7 9.4 0.2 2.8 2 1 0 2 2 2 0 AAA domain DUF2493 PF10686.4 EON97158.1 - 0.095 12.2 0.1 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Viral_helicase1 PF01443.13 EON97158.1 - 0.13 11.7 0.1 16 4.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Uma2 PF05685.7 EON97160.1 - 0.056 12.7 0.1 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Putative restriction endonuclease adh_short PF00106.20 EON97161.1 - 5.9e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97161.1 - 7.2e-07 29.2 0.1 1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amidase PF01425.16 EON97163.1 - 2.9e-38 131.8 0.5 1.1e-31 110.1 0.2 2.5 1 1 1 2 2 2 2 Amidase Collar PF07484.7 EON97163.1 - 0.048 13.4 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Collar Domain DHDPS PF00701.17 EON97164.1 - 9.8e-43 145.8 0.0 1.3e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fructosamin_kin PF03881.9 EON97165.1 - 4.5e-32 111.1 0.0 5.5e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EON97165.1 - 6.2e-06 26.1 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EON97165.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Cyclin_N PF00134.18 EON97166.1 - 2.2e-14 53.1 0.0 3.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EON97166.1 - 2.8e-10 40.7 0.3 2.8e-10 40.7 0.2 2.0 2 1 0 2 2 2 1 Cyclin Period_C PF12114.3 EON97166.1 - 0.16 11.5 7.1 0.25 10.9 4.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2217 PF10265.4 EON97166.1 - 3.8 6.1 6.6 5.5 5.6 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cupin_2 PF07883.6 EON97167.1 - 1.2e-13 50.3 1.6 6.4e-13 48.0 0.1 2.5 2 1 1 3 3 3 1 Cupin domain Cupin_3 PF05899.7 EON97167.1 - 1.7e-05 24.1 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.7 EON97167.1 - 0.00021 20.7 0.0 0.00023 20.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_1 PF00190.17 EON97167.1 - 0.0021 17.5 0.0 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 Cupin EutQ PF06249.7 EON97167.1 - 0.0028 17.1 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 EON97167.1 - 0.0054 16.3 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EON97167.1 - 0.04 13.8 0.1 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_7 PF12973.2 EON97167.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain AraC_binding PF02311.14 EON97167.1 - 0.086 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Tropomodulin PF03250.9 EON97168.1 - 0.058 12.9 1.2 0.23 10.9 0.8 2.0 1 1 0 1 1 1 0 Tropomodulin Fungal_trans_2 PF11951.3 EON97169.1 - 1.4e-18 66.6 1.0 1.7e-18 66.3 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EON97170.1 - 4e-72 242.4 0.0 4.9e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97170.1 - 1.5e-30 106.1 0.0 2e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON97170.1 - 0.0016 17.5 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON97170.1 - 0.011 15.4 0.2 0.031 14.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family WSC PF01822.14 EON97171.1 - 4.6e-37 125.8 24.7 1.2e-20 73.1 6.2 4.0 3 1 0 3 3 3 2 WSC domain FAD_binding_4 PF01565.18 EON97172.1 - 4.3e-25 87.8 0.2 8.6e-25 86.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON97172.1 - 0.085 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Hira PF07569.6 EON97173.1 - 2.8e-87 291.5 0.0 6.6e-87 290.3 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EON97173.1 - 9.1e-43 142.6 17.2 7.4e-07 28.8 0.0 8.9 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 EON97173.1 - 1.5e-11 43.5 1.0 3.4e-11 42.3 0.7 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EON97173.1 - 0.0001 21.8 0.3 5 6.9 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Rav1p_C PF12234.3 EON97173.1 - 0.34 9.0 0.0 4.7 5.2 0.0 2.0 2 0 0 2 2 2 0 RAVE protein 1 C terminal DUF1996 PF09362.5 EON97174.1 - 3.1e-13 49.9 1.2 4.7e-13 49.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Amidase PF01425.16 EON97175.1 - 4.4e-73 246.6 0.0 5.7e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Amidase HEAT_EZ PF13513.1 EON97176.1 - 3.7e-21 74.9 15.9 1.7e-05 25.1 0.0 12.7 12 2 2 14 14 14 3 HEAT-like repeat HEAT_2 PF13646.1 EON97176.1 - 1.9e-20 72.9 19.7 8.8e-05 22.7 0.0 9.5 3 2 8 11 11 11 5 HEAT repeats HEAT PF02985.17 EON97176.1 - 2.1e-17 61.5 8.6 0.0014 18.5 0.0 10.9 13 0 0 13 13 11 3 HEAT repeat Adaptin_N PF01602.15 EON97176.1 - 1.8e-10 39.8 0.6 0.019 13.2 0.0 5.5 4 2 2 6 6 6 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EON97176.1 - 2.2e-10 40.7 0.0 0.0045 17.3 0.0 5.4 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EON97176.1 - 1.1e-09 38.0 3.5 2.5e-07 30.4 0.0 4.1 5 0 0 5 5 4 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EON97176.1 - 3.8e-06 26.8 1.9 0.077 12.8 0.0 5.1 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EON97176.1 - 1.7e-05 24.3 0.6 0.028 13.7 0.0 4.2 5 1 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EON97176.1 - 1.9e-05 24.2 13.7 0.59 10.0 0.0 8.9 12 0 0 12 12 12 2 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EON97176.1 - 0.00014 21.8 0.8 0.049 13.5 0.1 3.7 4 0 0 4 4 4 1 Parkin co-regulated protein DUF577 PF04510.7 EON97176.1 - 0.0046 16.6 0.1 0.027 14.1 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF577) V-ATPase_H_N PF03224.9 EON97176.1 - 0.0075 15.4 5.7 8.5 5.3 0.9 4.2 3 2 2 5 5 5 1 V-ATPase subunit H YukD PF08817.5 EON97176.1 - 0.016 15.7 0.2 11 6.6 0.0 3.8 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD MMS19_C PF12460.3 EON97176.1 - 0.032 12.9 8.2 4.6 5.8 0.0 5.1 3 2 0 5 5 5 0 RNAPII transcription regulator C-terminal RabGAP-TBC PF00566.13 EON97176.1 - 0.062 12.7 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Rab-GTPase-TBC domain YfbU PF03887.9 EON97176.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 YfbU domain DUF3385 PF11865.3 EON97176.1 - 0.19 11.6 1.4 30 4.4 0.0 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF3385) p450 PF00067.17 EON97177.1 - 9.9e-60 202.3 0.0 1.2e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HECT PF00632.20 EON97178.1 - 2.8e-79 266.5 0.0 4.2e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CobT PF06213.7 EON97178.1 - 0.0028 16.8 4.7 0.0028 16.8 3.3 2.8 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Arm PF00514.18 EON97178.1 - 0.0076 16.0 2.0 1.4 8.8 0.0 4.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RRN3 PF05327.6 EON97178.1 - 0.42 8.6 5.3 0.76 7.8 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 EON97178.1 - 1.2 7.2 5.4 2 6.5 3.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Zds_C PF08632.5 EON97179.1 - 5.8e-30 102.4 0.5 9.8e-30 101.7 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF3682 PF12446.3 EON97179.1 - 2.9 8.1 24.4 0.51 10.6 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) MFS_1 PF07690.11 EON97180.1 - 7.9e-18 64.2 5.5 9.9e-18 63.9 3.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Rap1_C PF11626.3 EON97181.1 - 5.4e-20 71.0 0.0 8.4e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubie_methyltran PF01209.13 EON97183.1 - 1.9e-72 243.1 0.0 2.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EON97183.1 - 1.3e-12 47.9 0.0 4.2e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON97183.1 - 9.1e-12 44.8 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON97183.1 - 7.7e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON97183.1 - 1.6e-09 38.1 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON97183.1 - 8.2e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON97183.1 - 9.7e-08 32.5 0.0 2.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON97183.1 - 4.3e-05 23.5 0.3 0.00016 21.6 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON97183.1 - 0.059 12.7 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EON97183.1 - 0.096 12.3 0.0 0.57 9.7 0.0 2.0 1 1 0 2 2 2 0 Hypothetical methyltransferase FF PF01846.14 EON97184.1 - 2.9e-10 39.9 9.6 9.2e-08 31.9 0.1 3.7 3 0 0 3 3 3 2 FF domain WW PF00397.21 EON97184.1 - 1.8e-09 37.3 4.5 3.9e-09 36.1 1.4 2.6 2 0 0 2 2 2 1 WW domain GBP_C PF02841.9 EON97184.1 - 5.5 6.0 12.4 12 4.9 8.6 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Bac_rhamnosid PF05592.6 EON97185.1 - 3.9e-27 94.6 1.0 8.2e-22 77.0 0.4 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Prenyltrans_2 PF13249.1 EON97185.1 - 0.012 15.9 0.9 0.034 14.5 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase-like DUF1923 PF09083.5 EON97185.1 - 0.075 12.5 0.6 3 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) MARVEL PF01284.18 EON97186.1 - 2e-08 34.1 14.4 6.1e-07 29.3 10.0 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 EON97186.1 - 0.0042 16.6 2.4 0.0084 15.6 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF747 PF05346.6 EON97187.1 - 4.3e-104 348.1 0.0 1.6e-84 283.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic membrane protein family Sugar_tr PF00083.19 EON97188.1 - 1.4e-85 287.5 15.6 1.6e-85 287.3 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97188.1 - 2.6e-31 108.6 16.5 3.9e-31 108.0 11.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EON97188.1 - 0.00014 20.2 4.4 0.00071 17.9 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EON97188.1 - 0.00045 18.7 1.5 0.00045 18.7 1.0 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.11 EON97188.1 - 0.0037 16.7 2.3 0.0037 16.7 1.6 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 PalH PF08733.5 EON97188.1 - 0.039 12.7 5.3 0.061 12.1 3.6 1.3 1 0 0 1 1 1 0 PalH/RIM21 Tmemb_170 PF10190.4 EON97188.1 - 0.047 13.7 2.9 0.062 13.3 0.1 2.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 OATP PF03137.15 EON97188.1 - 0.42 8.6 8.5 0.016 13.2 1.7 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.16 EON97188.1 - 1.9 7.1 11.1 0.42 9.3 2.8 2.4 2 1 0 2 2 2 0 POT family adh_short PF00106.20 EON97189.1 - 3e-19 69.5 4.5 1.5e-18 67.2 3.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97189.1 - 8.7e-17 61.6 0.0 2.4e-16 60.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON97189.1 - 1.6e-09 37.6 1.9 2.2e-09 37.2 0.5 1.7 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EON97189.1 - 0.02 14.9 0.3 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EON97189.1 - 0.037 13.6 1.6 0.056 13.0 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EON97189.1 - 0.35 10.9 1.5 0.74 9.9 0.8 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OEP PF02321.13 EON97190.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Pro_CA PF00484.14 EON97191.1 - 2.9e-13 50.0 0.0 7.9e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Prefoldin_2 PF01920.15 EON97191.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit Complex1_LYR_2 PF13233.1 EON97193.1 - 6.5e-20 71.5 0.0 7.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EON97193.1 - 0.0007 19.3 0.9 0.00099 18.8 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EON97193.1 - 0.19 11.9 1.4 0.32 11.2 1.0 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Oxidored_molyb PF00174.14 EON97194.1 - 1.3e-45 154.8 0.0 1.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EON97194.1 - 2.8e-23 81.9 1.1 4.6e-23 81.2 0.8 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 EON97194.1 - 0.012 15.5 0.0 0.061 13.2 0.0 2.1 2 0 0 2 2 2 0 SLBB domain Ank_2 PF12796.2 EON97195.1 - 9.2e-26 90.0 0.9 8.8e-16 58.0 0.4 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EON97195.1 - 1.6e-25 87.5 5.6 1e-08 34.5 0.5 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EON97195.1 - 8.9e-18 62.6 1.4 1.2e-05 25.0 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EON97195.1 - 2.4e-15 56.2 8.0 3.4e-08 33.4 1.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON97195.1 - 3.2e-15 56.1 1.2 3.2e-08 33.8 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Amidase PF01425.16 EON97196.1 - 2.7e-19 69.3 0.2 6e-18 64.9 0.1 2.1 2 0 0 2 2 2 2 Amidase Aha1_N PF09229.6 EON97197.1 - 5e-39 133.2 1.4 7.5e-39 132.6 1.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EON97197.1 - 2.6e-19 69.5 0.3 2.6e-19 69.5 0.2 1.9 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EON97197.1 - 0.00022 21.3 2.2 0.029 14.5 0.5 2.2 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Peptidase_S58 PF03576.9 EON97198.1 - 4.1e-108 361.4 3.1 5.7e-108 360.9 2.2 1.2 1 0 0 1 1 1 1 Peptidase family S58 MFS_1 PF07690.11 EON97199.1 - 4.5e-24 84.8 15.7 5.5e-24 84.5 10.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EON97199.1 - 3.1e-10 38.9 4.1 3.5e-10 38.7 2.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EON97199.1 - 9.9e-05 21.0 2.0 9.9e-05 21.0 1.4 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter HIG_1_N PF04588.8 EON97199.1 - 0.026 14.2 0.1 0.071 12.8 0.1 1.7 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DLH PF01738.13 EON97200.1 - 2.3e-23 82.6 0.0 2.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EON97200.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF604 PF04646.7 EON97201.1 - 3.3e-09 36.3 0.3 8.1e-09 35.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 EON97201.1 - 2e-08 33.7 0.0 5e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Fringe-like PIR PF00399.14 EON97202.1 - 1.7e-11 43.0 24.5 0.00078 18.6 0.4 5.2 4 0 0 4 4 4 4 Yeast PIR protein repeat zf-U1 PF06220.7 EON97203.1 - 3.9e-08 32.7 0.6 7.6e-08 31.7 0.4 1.5 1 0 0 1 1 1 1 U1 zinc finger Acetyltransf_2 PF00797.12 EON97204.1 - 2.3e-16 60.0 0.0 3.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MFS_1 PF07690.11 EON97205.1 - 3.2e-21 75.4 26.8 2.3e-12 46.3 5.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MMR_HSR1 PF01926.18 EON97206.1 - 1.8e-17 63.3 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EON97206.1 - 3.8e-09 36.2 0.0 1.1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EON97206.1 - 7.8e-05 22.0 0.0 0.003 16.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EON97206.1 - 0.00066 19.5 0.0 0.092 12.5 0.1 2.2 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EON97206.1 - 0.0035 16.5 0.1 0.0065 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EON97206.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EON97206.1 - 0.0067 16.7 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 EON97206.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 EON97206.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Septin Mitofilin PF09731.4 EON97207.1 - 8.1 4.9 15.5 8.5 4.9 10.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dynamin_N PF00350.18 EON97208.1 - 2.7e-23 82.6 0.0 1.7e-22 80.0 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EON97208.1 - 7.5e-08 31.4 0.2 1.8e-05 23.7 0.0 2.9 3 1 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EON97208.1 - 0.017 15.0 0.0 0.24 11.3 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EON97208.1 - 0.022 15.2 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 EON97208.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EON97208.1 - 0.04 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EON97208.1 - 0.06 13.6 0.6 0.18 12.0 0.1 2.1 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.13 EON97208.1 - 0.17 11.1 0.0 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PhyH PF05721.8 EON97210.1 - 6.9e-14 52.3 0.0 9.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EON97210.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EON97210.1 - 0.08 13.4 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NTP_transferase PF00483.18 EON97211.1 - 3.9e-28 98.4 0.0 4.8e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EON97211.1 - 2.3e-09 36.3 8.8 9.7e-06 24.8 0.0 4.1 5 0 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EON97211.1 - 1.3e-05 25.3 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EON97211.1 - 0.034 13.6 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2OG-FeII_Oxy_2 PF13532.1 EON97213.1 - 9e-32 110.4 0.0 1.8e-31 109.5 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EON97213.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IF-2B PF01008.12 EON97214.1 - 6.2e-21 74.6 0.2 3.5e-15 55.7 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.23 EON97214.1 - 1.7e-09 37.3 0.2 3.9e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Peptidase_MA_2 PF13485.1 EON97215.1 - 0.00022 21.2 2.3 0.00023 21.2 0.7 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily BSP PF04450.7 EON97215.1 - 0.00096 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF1264 PF06884.6 EON97216.1 - 1.6e-42 144.8 0.5 1.8e-42 144.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) ASCH PF04266.9 EON97217.1 - 0.0034 17.7 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Fe-ADH PF00465.14 EON97218.1 - 2.6e-98 329.0 0.0 3.1e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EON97218.1 - 2.4e-15 56.5 0.0 5.7e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EON97218.1 - 0.004 16.5 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DNA_photolyase PF00875.13 EON97218.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase Sec3_C PF09763.4 EON97219.1 - 1.6e-235 783.5 0.9 2e-235 783.1 0.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EON97219.1 - 4.8e-32 109.6 0.0 9.9e-32 108.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EON97219.1 - 0.00027 20.9 2.8 0.0012 18.9 0.0 3.3 4 0 0 4 4 4 1 Sec3 exocyst complex subunit L_biotic_typeA PF04604.8 EON97219.1 - 0.044 13.4 0.0 0.18 11.5 0.0 2.0 1 0 0 1 1 1 0 Type-A lantibiotic DUF2433 PF10360.4 EON97220.1 - 1.4e-51 174.2 0.0 2.2e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EON97220.1 - 0.004 17.0 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EON97220.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase TFIIA PF03153.8 EON97220.1 - 0.4 10.5 7.4 0.77 9.5 5.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2360 PF10152.4 EON97220.1 - 0.45 10.7 11.4 5.8 7.1 7.9 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3275 PF11679.3 EON97220.1 - 2.1 7.9 5.5 5.9 6.4 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PAT1 PF09770.4 EON97220.1 - 9.6 4.2 10.8 16 3.5 7.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 K_oxygenase PF13434.1 EON97221.1 - 6.6e-85 285.0 0.0 1.2e-82 277.6 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EON97221.1 - 1.1e-08 35.4 0.1 9.2e-08 32.3 0.0 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON97221.1 - 1.2e-06 28.3 1.2 0.00026 20.8 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EON97221.1 - 3.6e-06 27.0 0.0 1e-05 25.5 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EON97223.1 - 1.5e-44 151.2 0.1 3.6e-44 150.0 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON97223.1 - 3.8e-12 45.8 0.0 5.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EON97223.1 - 0.00012 21.9 0.1 0.0002 21.2 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EON97223.1 - 0.00048 20.0 0.1 0.00086 19.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EON97223.1 - 0.00066 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 EON97223.1 - 0.016 14.5 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EON97223.1 - 0.062 13.7 0.2 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 EON97223.1 - 0.082 13.0 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Smr PF01713.16 EON97224.1 - 1.8e-07 31.2 0.2 4.2e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EON97224.1 - 0.0014 18.5 7.1 0.0032 17.4 5.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 EON97224.1 - 0.0017 17.7 0.1 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain Pex19 PF04614.7 EON97224.1 - 0.12 12.0 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Pex19 protein family Acetyltransf_1 PF00583.19 EON97225.1 - 1.3e-10 41.1 0.2 3.3e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON97225.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON97225.1 - 2.8e-07 30.6 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EON97225.1 - 0.00043 20.1 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EON97225.1 - 0.00045 20.0 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EON97225.1 - 0.0023 18.1 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3626 PF12294.3 EON97225.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) E1_dh PF00676.15 EON97226.1 - 1.7e-88 296.2 0.0 2e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EON97226.1 - 0.00077 19.0 0.0 0.015 14.9 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EON97226.1 - 0.0093 14.9 0.0 0.039 12.8 0.0 1.9 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase CAP59_mtransfer PF11735.3 EON97227.1 - 2.5e-55 187.3 0.0 3.4e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Patched PF02460.13 EON97228.1 - 1.8e-73 247.8 15.9 2.6e-72 243.9 11.0 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EON97228.1 - 9.4e-51 171.2 4.5 9.4e-51 171.2 3.1 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EON97228.1 - 5.8e-07 28.5 28.4 5.1e-05 22.1 4.6 2.5 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.9 EON97228.1 - 2.4e-05 24.0 3.8 4.9e-05 23.0 2.6 1.5 1 0 0 1 1 1 1 Folate receptor family Sugar_tr PF00083.19 EON97229.1 - 2.9e-71 240.4 22.1 3.4e-71 240.1 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97229.1 - 4.6e-23 81.5 28.6 5.2e-17 61.5 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1305 PF06996.6 EON97232.1 - 0.036 13.0 0.0 0.04 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) TPPII_N PF12583.3 EON97234.1 - 2.8 8.0 6.4 4 7.5 4.4 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Na_Ca_ex PF01699.19 EON97235.1 - 4.7e-24 84.5 5.9 6e-24 84.2 4.1 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein MARVEL PF01284.18 EON97235.1 - 0.002 17.9 1.6 0.0029 17.4 1.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain HemY_N PF07219.8 EON97235.1 - 0.23 11.0 2.5 0.41 10.2 1.7 1.4 1 0 0 1 1 1 0 HemY protein N-terminus MerT PF02411.10 EON97235.1 - 5.5 6.8 7.8 0.36 10.6 0.9 2.4 1 1 1 2 2 2 0 MerT mercuric transport protein Tubulin PF00091.20 EON97236.1 - 1.3e-63 214.7 0.0 1.7e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EON97236.1 - 1.1e-43 148.2 0.0 1.8e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EON97236.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF726 PF05277.7 EON97237.1 - 2.6e-128 427.7 3.3 3.7e-128 427.2 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EON97237.1 - 0.077 12.7 0.3 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EON97237.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) CAP_GLY PF01302.20 EON97238.1 - 2.2e-19 68.9 0.1 3.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EON97238.1 - 1.4e-14 53.2 13.8 6.8e-06 25.5 2.9 5.3 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EON97238.1 - 1.3e-09 36.7 11.6 0.47 10.6 0.0 7.0 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EON97238.1 - 2.1e-08 33.7 13.7 8.6e-05 22.2 3.7 4.6 3 1 3 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EON97238.1 - 1.5e-05 24.5 15.1 0.84 9.8 0.1 6.9 8 0 0 8 8 8 2 Leucine Rich repeat LRR_7 PF13504.1 EON97238.1 - 0.00028 20.5 15.4 14 6.3 0.1 6.8 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 EON97238.1 - 0.0093 15.5 0.1 0.36 10.3 0.2 2.4 2 0 0 2 2 2 1 Leucine-rich repeat RNase_HII PF01351.13 EON97238.1 - 0.13 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease HII DUF3453 PF11935.3 EON97239.1 - 8.1e-20 71.2 0.7 2e-17 63.4 0.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3453) Adaptin_N PF01602.15 EON97239.1 - 0.53 8.5 2.1 2 6.6 0.1 2.4 2 2 0 2 2 2 0 Adaptin N terminal region VSP PF03302.8 EON97240.1 - 5.2e-05 22.0 1.4 7.7e-05 21.4 1.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 EON97240.1 - 0.0024 17.1 0.6 0.0066 15.7 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EON97240.1 - 0.0026 17.0 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Phage_HK97_TLTM PF06120.6 EON97240.1 - 0.0069 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Tail length tape measure protein Mid2 PF04478.7 EON97240.1 - 0.019 14.3 0.2 0.042 13.2 0.2 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2029 PF09594.5 EON97240.1 - 0.079 12.4 1.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) AA_permease PF00324.16 EON97241.1 - 6.8e-142 473.1 33.1 8.6e-142 472.8 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON97241.1 - 3.2e-38 131.4 34.3 4.4e-38 130.9 23.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 EON97242.1 - 1.5e-27 96.1 0.0 2.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF948 PF06103.6 EON97244.1 - 0.016 15.0 7.9 0.17 11.7 1.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2573 PF10835.3 EON97244.1 - 0.13 12.3 1.8 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) DUF730 PF05325.6 EON97244.1 - 0.73 9.6 7.1 17 5.2 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF730) Baculo_PEP_C PF04513.7 EON97244.1 - 3.4 7.4 5.7 1.6 8.5 1.5 2.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRKCSH-like PF12999.2 EON97244.1 - 6.5 6.2 10.7 0.73 9.3 3.5 2.1 1 1 0 2 2 2 0 Glucosidase II beta subunit-like Peptidase_C6 PF00851.13 EON97244.1 - 8.3 4.9 9.0 0.88 8.1 2.7 1.7 1 1 0 2 2 2 0 Helper component proteinase SHR3_chaperone PF08229.6 EON97245.1 - 3.2e-70 235.0 0.0 3.7e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RRM_1 PF00076.17 EON97247.1 - 3e-12 45.9 0.0 5.4e-08 32.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97247.1 - 2e-10 40.3 0.0 0.00059 19.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON97247.1 - 3e-09 36.7 0.0 2.2e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MaoC_dehydratas PF01575.14 EON97248.1 - 1.3e-21 76.2 0.0 2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EON97248.1 - 1.1e-05 25.2 0.0 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Sds3 PF08598.6 EON97249.1 - 1.6e-25 89.8 6.4 1.6e-25 89.8 4.5 4.5 1 1 1 2 2 2 1 Sds3-like PP2C_2 PF13672.1 EON97250.1 - 2.7e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EON97250.1 - 0.00034 20.3 0.0 0.0017 18.1 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EON97250.1 - 0.18 11.1 0.1 2.3 7.5 0.0 2.1 1 1 0 2 2 2 0 Protein phosphatase 2C Serglycin PF04360.7 EON97251.1 - 0.12 12.1 0.4 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 Serglycin PUCC PF03209.10 EON97253.1 - 0.0037 16.0 6.8 0.0065 15.2 4.7 1.3 1 0 0 1 1 1 1 PUCC protein HAMP PF00672.20 EON97255.1 - 1.3e-49 166.1 17.4 2.9e-10 40.1 0.2 7.2 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EON97255.1 - 1.3e-29 102.1 0.5 4.7e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EON97255.1 - 3.1e-29 101.2 1.1 7.3e-27 93.5 0.5 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EON97255.1 - 2.9e-17 62.4 0.6 2.9e-17 62.4 0.4 4.1 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EON97255.1 - 0.0033 15.9 18.4 0.16 10.3 2.7 3.6 1 1 3 4 4 4 4 AAA domain DUF883 PF05957.8 EON97255.1 - 0.23 11.8 18.0 1.4 9.3 0.1 6.0 5 1 2 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF2365 PF10157.4 EON97255.1 - 0.41 10.5 14.1 8.9 6.1 0.0 6.1 5 3 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) NAAA-beta PF15508.1 EON97255.1 - 0.51 10.7 4.4 26 5.2 0.1 5.3 4 3 2 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF948 PF06103.6 EON97255.1 - 0.84 9.5 34.8 1 9.2 0.1 8.6 5 1 3 9 9 9 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.7 EON97255.1 - 3.2 7.7 7.5 5.5 7.0 0.0 4.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat DUF749 PF05370.6 EON97255.1 - 6.6 6.7 8.2 34 4.4 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF749) Chitin_bind_4 PF00379.18 EON97256.1 - 0.082 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Insect cuticle protein ATP-synt_E PF05680.7 EON97257.1 - 9.5e-25 86.3 0.5 1e-24 86.2 0.4 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 EON97257.1 - 0.018 15.1 0.9 0.024 14.8 0.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) TPR_18 PF13512.1 EON97257.1 - 0.028 14.4 0.1 0.05 13.6 0.0 1.3 1 1 0 1 1 1 0 Tetratricopeptide repeat ABC_trans_N PF14510.1 EON97257.1 - 0.028 14.4 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Drf_GBD PF06371.8 EON97257.1 - 0.14 11.4 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain adh_short PF00106.20 EON97258.1 - 1.8e-12 47.5 0.2 1.3e-10 41.4 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97258.1 - 1e-06 28.7 0.2 0.0017 18.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EON97258.1 - 0.0011 19.0 0.2 0.0021 18.0 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EON97258.1 - 0.01 15.3 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EON97258.1 - 0.011 15.3 0.1 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EON97258.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EON97258.1 - 0.044 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain SnoaL PF07366.7 EON97259.1 - 7.2e-24 83.7 0.0 8.4e-17 60.9 0.0 2.5 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EON97259.1 - 1.8e-17 63.5 0.1 1e-12 48.3 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Aldo_ket_red PF00248.16 EON97260.1 - 9.6e-50 168.9 0.0 1.3e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 EON97260.1 - 0.051 13.1 0.1 0.74 9.3 0.0 2.2 1 1 0 2 2 2 0 Amidohydrolase WD40 PF00400.27 EON97261.1 - 2.8e-23 80.9 9.1 3.5e-06 26.6 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EON97261.1 - 0.00064 17.9 3.0 0.0013 16.9 0.4 2.5 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EON97261.1 - 0.0014 17.4 0.0 2.5 6.7 0.0 3.2 1 1 0 3 3 3 2 Nup133 N terminal like Cyclin_N PF00134.18 EON97261.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain HET PF06985.6 EON97262.1 - 1.4e-13 51.1 0.0 5.7e-12 45.9 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SnoaL PF07366.7 EON97263.1 - 0.00019 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EON97263.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pkinase PF00069.20 EON97264.1 - 9.6e-48 162.5 0.0 1.5e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97264.1 - 1e-26 93.5 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EON97264.1 - 4.9e-10 39.3 0.1 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EON97264.1 - 0.006 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EON97264.1 - 0.011 15.4 0.1 0.6 9.7 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EON97264.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EON97264.1 - 0.13 10.9 1.5 0.29 9.8 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-C2H2 PF00096.21 EON97265.1 - 0.015 15.6 2.6 0.015 15.6 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON97265.1 - 0.64 10.4 18.6 0.082 13.2 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.27 EON97266.1 - 1.4e-20 72.3 5.8 4.5e-07 29.5 0.1 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat Cupin_2 PF07883.6 EON97268.1 - 2.8e-08 33.1 0.0 4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EON97268.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EON97268.1 - 0.041 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.17 EON97268.1 - 0.063 12.7 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EON97268.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EON97268.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HMGL-like PF00682.14 EON97269.1 - 0.014 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 HMGL-like HpcH_HpaI PF03328.9 EON97270.1 - 4.2e-33 114.1 0.0 7.4e-33 113.2 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EON97270.1 - 7.4e-12 44.7 0.0 9.7e-07 27.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.1 EON97270.1 - 0.035 12.4 0.0 0.058 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Coiled-coil_56 PF09813.4 EON97271.1 - 6.2e-05 22.9 0.0 6.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 TPR_12 PF13424.1 EON97272.1 - 0.0035 17.2 1.0 0.013 15.4 0.3 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat T2SF PF00482.18 EON97272.1 - 0.076 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F TPR_14 PF13428.1 EON97272.1 - 0.78 10.5 5.3 2 9.3 2.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat RRM_5 PF13893.1 EON97273.1 - 1.2e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON97273.1 - 1.1e-07 31.3 0.0 2.6e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EON97273.1 - 4.4e-05 23.1 0.0 8.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Calcipressin RRM_6 PF14259.1 EON97273.1 - 5.2e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 EON97274.1 - 1.2e-32 113.2 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Cys_Met_Meta_PP PF01053.15 EON97275.1 - 1e-58 198.5 0.0 1.9e-58 197.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EON97275.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II RTA1 PF04479.8 EON97276.1 - 6.8e-57 192.5 15.2 6.8e-57 192.5 10.6 1.8 2 0 0 2 2 2 1 RTA1 like protein Kei1 PF08552.6 EON97276.1 - 0.02 14.5 1.5 0.02 14.5 1.0 2.6 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 zf-DHHC PF01529.15 EON97276.1 - 1.3 8.3 11.4 8.4 5.7 0.7 2.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase Hep_59 PF07052.6 EON97277.1 - 4.5e-06 26.9 0.1 4.5e-06 26.9 0.1 2.3 2 1 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 HisG PF01634.13 EON97278.1 - 7.5e-49 165.4 0.6 1.4e-46 158.0 0.4 2.3 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EON97278.1 - 1.6e-28 98.4 0.1 3.5e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain TMEM154 PF15102.1 EON97280.1 - 0.00026 20.6 1.0 0.00049 19.8 0.7 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EON97280.1 - 0.00059 18.2 0.7 0.001 17.4 0.5 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E AJAP1_PANP_C PF15298.1 EON97280.1 - 0.0063 16.4 6.1 0.0063 16.4 4.2 1.8 2 0 0 2 2 2 1 AJAP1/PANP C-terminus DUF1191 PF06697.7 EON97280.1 - 0.012 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EON97280.1 - 0.022 14.0 0.8 0.051 12.8 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DAP10 PF07213.6 EON97280.1 - 0.041 13.6 0.5 0.13 11.9 0.4 1.8 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.1 EON97280.1 - 0.046 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EON97280.1 - 0.074 12.7 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Granulin PF00396.13 EON97280.1 - 0.13 12.3 30.0 0.28 11.2 3.9 3.7 2 1 1 3 3 3 0 Granulin Lustrin_cystein PF14625.1 EON97280.1 - 8.3 6.5 22.3 4.7 7.3 7.5 3.2 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain WD40 PF00400.27 EON97281.1 - 7.2e-20 70.0 14.3 7.7e-07 28.7 0.1 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 EON97281.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity adh_short_C2 PF13561.1 EON97282.1 - 5.8e-23 81.8 0.0 6.5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON97282.1 - 4.3e-18 65.7 0.0 6.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97282.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_deac_1 PF01522.16 EON97283.1 - 5.2e-27 93.9 0.0 8.8e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EON97283.1 - 0.0074 15.3 0.0 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase Fcf1 PF04900.7 EON97284.1 - 1.4e-28 98.9 1.6 1.4e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Fcf1 YL1 PF05764.8 EON97284.1 - 0.54 9.8 23.0 0.78 9.2 15.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.7 EON97284.1 - 4.8 4.8 6.4 5 4.7 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cnd2 PF05786.9 EON97285.1 - 8.3e-212 705.6 3.5 1.1e-211 705.2 2.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Vfa1 PF08432.5 EON97285.1 - 1.4 8.9 7.6 6.6 6.7 0.2 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 zf-RING_2 PF13639.1 EON97286.1 - 0.0054 16.5 6.1 0.0054 16.5 4.2 2.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EON97286.1 - 0.0088 15.6 6.6 0.0088 15.6 4.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Reovirus_L2 PF06016.6 EON97286.1 - 0.25 8.2 0.0 0.33 7.8 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) zf-C3HC4_3 PF13920.1 EON97286.1 - 0.3 10.7 18.4 0.04 13.6 3.3 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EON97286.1 - 0.86 9.3 8.5 0.26 11.0 1.2 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_4 PF07975.7 EON97286.1 - 2.2 8.3 7.4 0.4 10.7 0.4 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C3HC4_2 PF13923.1 EON97286.1 - 5.8 7.0 20.7 0.071 13.1 4.0 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 EON97286.1 - 7.2 6.6 9.2 5.4 7.0 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain Sporozoite_P67 PF05642.6 EON97287.1 - 0.64 7.8 9.2 0.73 7.6 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 EON97287.1 - 4.8 7.2 12.5 7.7 6.5 8.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein STT3 PF02516.9 EON97288.1 - 1.7e-131 439.5 34.8 1e-126 423.7 22.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 EON97288.1 - 0.0054 14.9 0.1 0.011 13.9 0.0 1.5 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Aldo_ket_red PF00248.16 EON97289.1 - 9e-56 188.7 0.0 1.1e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2187 PF09953.4 EON97289.1 - 0.084 12.6 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) PI-PLC-X PF00388.14 EON97290.1 - 2.3e-12 46.5 0.0 3.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HA2 PF04408.18 EON97291.1 - 4.2e-25 87.7 0.2 1.8e-24 85.6 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EON97291.1 - 1e-24 86.5 0.0 3.5e-23 81.5 0.0 2.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EON97291.1 - 5.6e-12 45.3 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EON97291.1 - 6.6e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EON97291.1 - 0.00012 22.2 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EON97291.1 - 0.00038 20.3 0.1 0.24 11.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EON97291.1 - 0.0011 17.9 0.0 0.0026 16.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EON97291.1 - 0.0013 17.8 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EON97291.1 - 0.013 14.9 0.1 0.034 13.5 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EON97291.1 - 0.021 14.5 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 EON97291.1 - 0.023 14.5 0.1 0.17 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EON97291.1 - 0.052 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain GAD PF02938.9 EON97291.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 GAD domain ABC_tran PF00005.22 EON97291.1 - 0.077 13.3 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF1570 PF07607.6 EON97291.1 - 0.082 12.9 1.3 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) Arch_ATPase PF01637.13 EON97291.1 - 0.091 12.4 1.8 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EON97291.1 - 0.13 12.2 0.4 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EON97291.1 - 0.13 11.9 1.2 0.33 10.5 0.1 2.2 3 0 0 3 3 2 0 NACHT domain RRM_1 PF00076.17 EON97292.1 - 1.3e-23 82.3 0.1 1.7e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON97292.1 - 1e-16 60.6 0.0 1.5e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97292.1 - 1.1e-10 41.1 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.24 EON97293.1 - 4.7e-07 29.9 0.3 3e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 EON97293.1 - 0.00031 20.8 0.0 0.00075 19.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF846 PF05832.7 EON97295.1 - 1.3e-52 177.3 4.4 1.5e-52 177.0 3.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Glyco_hydro_47 PF01532.15 EON97296.1 - 2.9e-167 556.9 0.3 4.1e-167 556.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans_2 PF11951.3 EON97297.1 - 6.1e-84 281.8 0.0 7.5e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2613 PF11021.3 EON97298.1 - 0.035 13.8 0.4 0.055 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) ANTH PF07651.11 EON97299.1 - 0.095 11.3 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Abhydrolase_6 PF12697.2 EON97301.1 - 7.8e-36 124.0 0.0 9.4e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97301.1 - 4.8e-14 52.4 0.1 8.9e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON97301.1 - 1.7e-13 50.5 0.0 6.4e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EON97301.1 - 5e-08 32.6 0.0 9.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 EON97301.1 - 2.6e-06 26.4 0.0 4.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 EON97301.1 - 7.9e-05 21.9 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EON97301.1 - 7.9e-05 22.9 0.0 0.00015 22.0 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.9 EON97301.1 - 0.004 15.6 0.0 0.14 10.6 0.0 2.1 2 0 0 2 2 2 1 Ndr family DLH PF01738.13 EON97301.1 - 0.0073 15.6 0.0 0.061 12.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EON97301.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EON97301.1 - 0.042 12.6 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 EON97301.1 - 0.043 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Rop-like PF05082.8 EON97302.1 - 0.059 12.8 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Rop-like DUF2413 PF10310.4 EON97302.1 - 0.068 11.9 3.8 0.071 11.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TipAS PF07739.8 EON97302.1 - 0.13 12.6 2.1 0.15 12.3 1.5 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain SGT1 PF07093.6 EON97302.1 - 0.54 8.5 8.2 0.56 8.5 5.7 1.0 1 0 0 1 1 1 0 SGT1 protein Pyr_redox_3 PF13738.1 EON97304.1 - 7.2e-29 101.3 0.0 3.4e-26 92.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON97304.1 - 6.5e-15 54.8 0.0 3.9e-12 45.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EON97304.1 - 6.9e-13 47.6 0.0 2.8e-10 39.0 0.0 2.9 3 1 0 4 4 4 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EON97304.1 - 8.2e-10 38.8 0.0 1.6e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON97304.1 - 3.4e-07 30.1 0.4 0.00045 20.0 0.1 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EON97304.1 - 1.1e-05 24.5 0.0 0.078 11.8 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON97304.1 - 1.6e-05 24.8 0.0 5.7e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EON97304.1 - 0.0011 18.0 0.5 0.0077 15.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EON97304.1 - 0.008 14.6 0.0 0.43 8.9 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EON97304.1 - 0.026 14.9 1.8 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON97304.1 - 0.046 12.5 0.1 8.2 5.1 0.0 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EON97304.1 - 0.1 11.5 0.0 13 4.5 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EON97304.1 - 0.16 12.2 0.0 3 8.1 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding EF-hand_1 PF00036.27 EON97306.1 - 4.9e-26 88.0 9.8 2.1e-06 26.6 0.1 5.5 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EON97306.1 - 5.6e-24 84.0 5.3 2.8e-10 40.1 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EON97306.1 - 2.1e-22 78.4 7.0 1.8e-10 40.2 0.0 4.5 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EON97306.1 - 2.6e-21 73.5 6.8 9e-05 22.0 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EON97306.1 - 6.7e-18 63.1 7.8 2.2e-05 23.5 0.3 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EON97306.1 - 0.1 12.4 1.3 0.6 10.0 0.0 2.8 4 0 0 4 4 4 0 EF-hand domain Sod_Fe_C PF02777.13 EON97307.1 - 1.8e-08 34.1 0.0 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sugar_tr PF00083.19 EON97308.1 - 2.1e-51 174.9 5.5 2.4e-51 174.7 3.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97308.1 - 0.00012 20.9 22.2 0.00023 19.9 14.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EON97308.1 - 0.027 14.2 0.1 0.027 14.2 0.1 2.9 3 0 0 3 3 3 0 MFS_1 like family ADH_zinc_N PF00107.21 EON97309.1 - 1.3e-15 57.1 2.1 1.6e-15 56.7 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON97309.1 - 7.9e-15 54.5 8.2 5.5e-13 48.6 5.7 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EON97309.1 - 0.00023 20.3 0.1 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EON97310.1 - 9.6e-17 61.3 0.2 1.7e-16 60.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97310.1 - 3.5e-15 56.4 0.1 6.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON97310.1 - 7.1e-05 22.5 0.1 0.00012 21.8 0.1 1.4 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EON97311.1 - 4e-14 52.2 0.1 6.2e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON97311.1 - 1.9e-12 46.8 0.5 1.1e-11 44.3 0.5 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EON97311.1 - 0.013 15.4 0.2 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EON97311.1 - 0.015 15.3 0.1 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EON97311.1 - 0.077 12.3 0.1 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 EON97312.1 - 5.7e-28 98.3 0.0 5e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON97312.1 - 1.9e-26 92.3 0.0 1.1e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EON97312.1 - 2e-14 53.9 0.0 7.5e-11 42.2 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON97312.1 - 6.1e-14 51.6 0.2 2e-08 33.5 0.0 3.2 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EON97312.1 - 1.7e-07 31.5 0.1 0.013 15.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON97312.1 - 1.8e-07 30.5 0.1 0.0012 18.0 0.1 3.1 2 1 1 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EON97312.1 - 9.1e-07 28.1 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EON97312.1 - 1.1e-06 28.4 0.0 0.00013 21.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON97312.1 - 2.5e-06 27.3 3.4 0.12 12.1 0.0 3.9 4 1 0 4 4 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EON97312.1 - 1.4e-05 23.8 0.1 0.0028 16.2 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.13 EON97312.1 - 4.7e-05 23.1 0.1 0.088 12.4 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EON97312.1 - 5.2e-05 22.2 0.0 0.1 11.4 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A TrkA_N PF02254.13 EON97312.1 - 8.8e-05 22.4 0.5 0.066 13.2 0.0 3.1 3 0 0 3 3 3 1 TrkA-N domain DAO PF01266.19 EON97312.1 - 0.00052 19.0 0.0 0.14 11.0 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase IlvN PF07991.7 EON97312.1 - 0.00055 19.3 0.2 0.015 14.7 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EON97312.1 - 0.00074 19.7 0.0 0.25 11.6 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EON97312.1 - 0.00078 19.5 0.1 3.2 7.8 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EON97312.1 - 0.0013 18.3 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EON97312.1 - 0.0019 17.1 0.0 0.036 12.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_2 PF03446.10 EON97312.1 - 0.0022 17.8 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EON97312.1 - 0.0026 17.2 0.0 1.9 7.8 0.0 2.8 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EON97312.1 - 0.0028 17.2 0.3 0.012 15.2 0.2 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Lycopene_cycl PF05834.7 EON97312.1 - 0.0036 16.2 0.1 0.27 10.1 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EON97312.1 - 0.0038 16.3 0.2 1.3 8.0 0.0 3.3 4 0 0 4 4 4 1 Thi4 family F420_oxidored PF03807.12 EON97312.1 - 0.0095 16.3 0.0 27 5.2 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CPSase_L_chain PF00289.17 EON97312.1 - 0.016 15.3 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ThiF PF00899.16 EON97312.1 - 0.051 13.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 ThiF family NAD_binding_10 PF13460.1 EON97312.1 - 0.062 13.3 0.2 6.8 6.6 0.0 2.7 3 0 0 3 3 2 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EON97312.1 - 0.072 12.4 0.2 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EON97312.1 - 0.095 12.4 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF498 PF04430.9 EON97312.1 - 0.1 12.1 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) UPF0146 PF03686.8 EON97312.1 - 0.15 11.8 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Collagen PF01391.13 EON97312.1 - 2 8.0 7.9 0.24 10.9 2.1 1.9 2 0 0 2 2 1 0 Collagen triple helix repeat (20 copies) ADH_zinc_N PF00107.21 EON97313.1 - 1e-28 99.4 0.2 1.9e-28 98.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON97313.1 - 1.4e-17 64.7 0.0 7.9e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON97313.1 - 1.8e-05 24.4 0.3 5.2e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EON97313.1 - 0.00067 19.3 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 EON97313.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EON97313.1 - 0.0049 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EON97313.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldolase_II PF00596.16 EON97314.1 - 1.5e-46 158.3 0.5 1.9e-46 157.9 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 EON97314.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) zf-MYND PF01753.13 EON97315.1 - 9.6e-11 41.3 12.7 1.6e-10 40.6 8.8 1.4 1 0 0 1 1 1 1 MYND finger Acetyltransf_1 PF00583.19 EON97316.1 - 0.0027 17.6 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EON97316.1 - 0.012 15.4 0.1 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON97316.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PDCD2_C PF04194.8 EON97317.1 - 9.9e-56 187.8 0.3 6.4e-55 185.2 0.0 2.1 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-C2H2 PF00096.21 EON97318.1 - 3.5e-10 39.5 18.8 9.9e-05 22.4 3.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EON97318.1 - 2e-09 37.2 11.4 0.00015 21.9 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EON97318.1 - 0.0006 19.9 16.0 0.48 10.8 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger AT_hook PF02178.14 EON97318.1 - 0.8 9.5 5.2 2.4 8.1 3.6 1.9 1 0 0 1 1 1 0 AT hook motif Bunya_G2 PF03563.8 EON97318.1 - 1 8.1 3.5 1.7 7.4 2.4 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-LYAR PF08790.6 EON97318.1 - 1.2 8.9 6.9 0.58 9.9 0.1 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 EON97318.1 - 2.1 8.3 9.9 0.57 10.1 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SprT-like PF10263.4 EON97318.1 - 2.6 7.6 7.0 2.3 7.8 1.2 2.3 1 1 1 2 2 2 0 SprT-like family Peptidase_S8 PF00082.17 EON97319.1 - 2.1e-40 138.6 4.8 4.5e-22 78.5 1.1 2.1 1 1 1 2 2 2 2 Subtilase family CBS PF00571.23 EON97320.1 - 7.8e-40 134.4 8.9 3.6e-10 39.4 0.0 4.9 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EON97320.1 - 2.9e-08 33.2 0.0 1.3e-07 31.1 0.0 2.2 2 1 0 2 2 2 1 PB1 domain FMN_dh PF01070.13 EON97321.1 - 7.1e-120 400.0 0.0 1.1e-119 399.4 0.0 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EON97321.1 - 5.9e-06 25.4 0.0 4e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EON97321.1 - 3.3e-05 23.1 0.0 0.26 10.3 0.0 3.0 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EON97321.1 - 0.00083 18.3 0.0 0.0017 17.3 0.0 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EON97321.1 - 0.0011 18.3 0.1 0.085 12.1 0.0 2.8 3 1 0 4 4 4 1 Histidine biosynthesis protein Bac_luciferase PF00296.15 EON97321.1 - 0.038 13.1 0.2 2.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Luciferase-like monooxygenase Glyco_transf_20 PF00982.16 EON97322.1 - 8e-150 499.4 0.0 1.1e-149 498.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EON97322.1 - 4.5e-76 254.8 0.1 1.6e-75 253.0 0.0 2.0 3 0 0 3 3 3 1 Trehalose-phosphatase HAD PF12710.2 EON97322.1 - 0.0084 16.2 0.2 0.12 12.5 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EON97322.1 - 0.052 13.7 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 Hydrolase_3 PF08282.7 EON97322.1 - 0.28 10.7 0.0 38 3.7 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase VID27 PF08553.5 EON97323.1 - 0 1128.8 0.0 0 1128.6 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2048 PF09752.4 EON97323.1 - 0.038 12.8 0.8 0.058 12.2 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) RasGAP PF00616.14 EON97324.1 - 5.7e-55 186.0 0.1 8.8e-54 182.1 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EON97324.1 - 1.6e-29 102.3 6.6 1.6e-29 102.3 4.6 2.1 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 EON97324.1 - 0.15 11.9 2.4 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain DUF972 PF06156.8 EON97324.1 - 1.3 9.3 9.5 5.7 7.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DNA_ligase_A_M PF01068.16 EON97325.1 - 2e-48 164.4 0.2 1.9e-46 157.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EON97325.1 - 1.5e-39 135.6 0.0 4.6e-39 134.0 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EON97325.1 - 1.3e-18 67.1 0.0 4e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Adaptin_N PF01602.15 EON97326.1 - 9.5e-149 496.0 2.8 1.3e-148 495.5 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EON97326.1 - 2.5e-26 92.6 0.3 2.6e-25 89.2 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EON97326.1 - 7.6e-18 64.5 0.1 3.8e-07 30.2 0.0 4.7 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EON97326.1 - 3e-11 42.4 3.5 0.016 15.2 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EON97326.1 - 2.6e-05 24.5 0.3 2 9.0 0.0 5.4 5 1 1 6 6 6 1 HEAT-like repeat UNC45-central PF11701.3 EON97326.1 - 7.6e-05 22.4 0.1 0.14 11.8 0.1 2.6 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.18 EON97326.1 - 0.0043 16.8 0.5 6.7 6.6 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EON97326.1 - 0.0051 16.5 0.0 0.091 12.5 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EON97326.1 - 0.031 13.6 0.2 2 7.7 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal AF0941-like PF14591.1 EON97326.1 - 0.55 10.3 2.9 1.4 9.0 0.8 2.5 3 0 0 3 3 3 0 AF0941-like Pyr_redox_3 PF13738.1 EON97327.1 - 1.3e-22 80.8 0.0 3.2e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON97327.1 - 6.6e-12 44.9 0.0 1e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EON97327.1 - 1.3e-11 43.4 0.0 3.8e-11 41.8 0.0 1.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EON97327.1 - 1.5e-09 38.0 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97327.1 - 5.6e-05 23.0 0.0 0.00016 21.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON97327.1 - 0.00011 22.0 0.1 0.00069 19.4 0.1 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EON97327.1 - 0.0029 16.5 2.0 0.28 10.0 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EON97327.1 - 0.011 14.2 0.1 1.5 7.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EON97327.1 - 0.018 14.1 0.0 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EON97327.1 - 0.052 12.4 0.1 0.078 11.8 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_2_N PF02837.13 EON97328.1 - 0.00042 19.8 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain RPAP1_C PF08620.5 EON97329.1 - 3.3e-29 100.5 0.0 5.3e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EON97329.1 - 5.3e-17 61.1 2.8 1.1e-16 60.1 1.9 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT_2 PF13646.1 EON97329.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 EON97329.1 - 0.14 12.3 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 HEAT repeat DUF1996 PF09362.5 EON97330.1 - 1.4e-60 204.8 0.2 2.3e-60 204.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HUN PF08729.5 EON97331.1 - 6.9e-14 51.4 0.8 1.5e-13 50.4 0.6 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain zf-H2C2 PF09337.5 EON97332.1 - 5.2e-16 57.7 3.6 5.2e-16 57.7 2.5 1.6 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EON97332.1 - 1.3e-05 25.1 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON97332.1 - 0.0044 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EON97332.1 - 0.0066 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Alpha-amylase PF00128.19 EON97333.1 - 2.9e-64 217.4 0.1 5e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_20 PF00982.16 EON97334.1 - 2e-197 656.4 0.0 2.3e-197 656.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 PCI_Csn8 PF10075.4 EON97335.1 - 4.3e-40 136.7 0.1 6.3e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EON97335.1 - 3.2e-22 79.1 0.5 4.1e-22 78.7 0.4 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3453 PF11935.3 EON97335.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Sugar_tr PF00083.19 EON97336.1 - 5.5e-96 321.8 19.9 6.3e-96 321.6 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97336.1 - 2.1e-22 79.2 24.9 3.1e-19 68.9 5.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97337.1 - 1e-74 251.7 16.0 1.2e-74 251.5 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2763 PF10961.3 EON97337.1 - 0.058 13.7 1.5 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Cpn60_TCP1 PF00118.19 EON97338.1 - 4.9e-149 497.0 0.4 5.6e-149 496.8 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EON97339.1 - 2.1e-140 468.5 5.1 2.4e-140 468.3 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SRP-alpha_N PF04086.8 EON97340.1 - 0.0046 16.3 16.4 0.0046 16.3 11.4 3.0 2 1 1 3 3 3 1 Signal recognition particle, alpha subunit, N-terminal Reprolysin_4 PF13583.1 EON97341.1 - 1.1e-06 28.3 0.1 1.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 EON97341.1 - 1.2e-06 28.2 0.3 1.8e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EON97341.1 - 2e-06 28.0 0.2 2.6e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EON97341.1 - 2.9e-06 27.3 0.1 4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 EON97341.1 - 8.9e-06 25.1 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EON97341.1 - 2e-05 24.3 0.6 5.1e-05 23.0 0.3 1.8 1 1 1 2 2 2 1 Matrixin Reprolysin_3 PF13582.1 EON97341.1 - 0.00073 20.0 0.2 0.001 19.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 EON97341.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.5 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M64 PF09471.5 EON97341.1 - 0.1 12.2 0.3 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 IgA Peptidase M64 Peptidase_M66 PF10462.4 EON97341.1 - 0.2 10.5 0.9 0.31 9.8 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 TauD PF02668.11 EON97343.1 - 5e-52 177.1 0.6 6e-52 176.8 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.7 EON97344.1 - 2.6e-53 181.0 0.0 7e-53 179.6 0.0 1.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) Aldose_epim PF01263.15 EON97345.1 - 9.4e-62 208.8 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.19 EON97346.1 - 2.2e-77 260.5 17.9 2.7e-77 260.2 12.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97346.1 - 2.3e-20 72.6 30.9 2.1e-15 56.2 9.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON97346.1 - 0.00045 18.7 34.7 0.0015 17.0 3.3 4.1 3 2 0 4 4 4 2 MFS/sugar transport protein AMP-binding PF00501.23 EON97347.1 - 6.1e-46 156.6 0.5 1.2e-22 79.9 0.2 2.1 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EON97347.1 - 2.1e-10 40.7 0.0 4.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EON97347.1 - 0.00017 20.6 0.7 0.00028 19.8 0.5 1.3 1 0 0 1 1 1 1 Male sterility protein DUF295 PF03478.13 EON97347.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) ApbA PF02558.11 EON97348.1 - 5.8e-28 97.2 0.1 7.8e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EON97348.1 - 8.2e-26 90.4 0.0 1.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Aminotran_3 PF00202.16 EON97349.1 - 7.5e-50 169.6 0.4 9.5e-50 169.3 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1744 PF08490.7 EON97350.1 - 3.6e-156 519.7 0.0 5e-156 519.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EON97350.1 - 2.3e-63 214.0 0.2 3.9e-63 213.2 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EON97350.1 - 1.8e-21 76.4 0.0 5.7e-21 74.8 0.0 1.7 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EON97350.1 - 7.7e-09 35.3 0.1 2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EON97350.1 - 3.3e-05 23.7 0.0 0.00018 21.3 0.0 2.3 2 1 0 2 2 2 1 RNase_H superfamily Asp_protease_2 PF13650.1 EON97350.1 - 0.083 13.4 0.0 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease adh_short PF00106.20 EON97351.1 - 3.3e-08 33.6 0.0 6.2e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97351.1 - 0.0061 16.2 0.0 0.0093 15.6 0.0 1.3 1 1 0 1 1 1 1 KR domain SIS PF01380.17 EON97351.1 - 0.015 14.9 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 SIS domain Ribosomal_S2 PF00318.15 EON97352.1 - 6.7e-51 172.5 0.0 4.2e-50 169.8 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein S2 Prenylcys_lyase PF07156.9 EON97353.1 - 4.2e-33 114.7 0.0 1.9e-24 86.2 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EON97353.1 - 5.7e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EON97353.1 - 3.5e-05 23.0 0.0 0.00067 18.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EON97353.1 - 8.7e-05 21.5 0.1 0.00078 18.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON97353.1 - 0.00023 21.1 0.8 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON97353.1 - 0.0016 18.5 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON97353.1 - 0.006 16.3 0.2 0.023 14.4 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EON97353.1 - 0.033 13.2 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EON97353.1 - 0.16 12.4 0.2 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AD PF09793.4 EON97353.1 - 0.3 10.9 1.6 0.31 10.8 0.1 1.8 2 0 0 2 2 2 0 Anticodon-binding domain DUF924 PF06041.6 EON97354.1 - 0.0002 21.1 0.1 0.00063 19.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PQQ_2 PF13360.1 EON97355.1 - 6.2e-15 55.3 1.0 9.9e-07 28.4 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 EON97355.1 - 2.2e-09 36.3 4.1 0.01 15.3 0.0 6.0 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.1 EON97355.1 - 0.00012 22.2 22.2 1.4 9.3 0.0 7.3 8 1 0 8 8 8 3 PQQ-like domain Pro-kuma_activ PF09286.6 EON97356.1 - 1.1e-23 83.8 0.1 2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EON97356.1 - 2e-05 23.8 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Amino_oxidase PF01593.19 EON97357.1 - 5.1e-50 170.8 0.4 8.7e-50 170.0 0.3 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 EON97357.1 - 1.3e-17 63.6 0.0 2.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 EON97357.1 - 3e-14 52.7 0.3 7.4e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EON97357.1 - 8.2e-10 38.1 2.2 8.8e-07 28.1 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EON97357.1 - 6.5e-08 32.8 0.4 9.4e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON97357.1 - 7.6e-08 31.7 0.4 1.5e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EON97357.1 - 1.5e-07 30.6 1.3 2.6e-07 29.8 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EON97357.1 - 5e-06 25.6 0.1 0.0054 15.6 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EON97357.1 - 0.00011 20.8 0.7 0.0003 19.3 0.5 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EON97357.1 - 0.00015 20.9 1.5 0.00022 20.4 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EON97357.1 - 0.00039 19.3 0.4 0.00074 18.4 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EON97357.1 - 0.001 19.0 1.0 0.0039 17.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON97357.1 - 0.0023 18.3 0.1 0.0049 17.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON97357.1 - 0.0048 16.0 0.4 0.0074 15.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EON97357.1 - 0.14 11.7 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease PF00324.16 EON97358.1 - 5.2e-67 226.2 35.4 3.5e-66 223.4 18.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EON97358.1 - 4.9e-22 78.0 32.3 8.1e-22 77.3 17.0 2.0 1 1 1 2 2 2 2 Amino acid permease DUF605 PF04652.11 EON97359.1 - 7.7 5.8 12.7 10 5.3 8.8 1.2 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 EON97360.1 - 8.3e-11 41.1 38.4 3e-08 32.7 3.7 3.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON97360.1 - 3.5e-07 28.8 9.3 3.5e-07 28.8 6.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EON97360.1 - 0.00019 19.6 7.1 0.022 12.8 0.1 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EON97360.1 - 0.00092 17.4 0.6 0.00092 17.4 0.4 2.8 3 0 0 3 3 3 1 Transmembrane secretion effector UPF0233 PF06781.7 EON97360.1 - 0.19 11.3 2.2 0.78 9.3 0.2 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) MFS_1 PF07690.11 EON97361.1 - 1.4e-14 53.5 63.3 1.4e-13 50.2 40.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON97361.1 - 1.9e-05 23.0 21.1 2.9e-05 22.4 13.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EON97362.1 - 7.1e-15 55.3 0.1 1e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97362.1 - 8.1e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON97362.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON97362.1 - 0.052 12.9 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON97362.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 EON97362.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EON97362.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EON97363.1 - 1.7e-40 138.9 0.0 2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M14 PF00246.19 EON97364.1 - 2.7e-38 132.1 2.5 5.5e-38 131.1 1.8 1.4 1 1 0 1 1 1 1 Zinc carboxypeptidase Cupin_2 PF07883.6 EON97365.1 - 9.4e-08 31.4 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EON97365.1 - 0.092 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Hydantoinase_B PF02538.9 EON97367.1 - 1.3e-151 505.4 0.0 1.3e-127 426.2 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EON97367.1 - 7.7e-91 304.1 0.1 2.6e-90 302.4 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EON97367.1 - 4.3e-58 195.7 0.6 1.3e-56 190.8 0.0 2.6 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EON97367.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF4364 PF14277.1 EON97367.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Terminase_5 PF06056.7 EON97367.1 - 0.21 11.1 0.0 12 5.5 0.0 2.6 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) AA_permease PF00324.16 EON97369.1 - 1.3e-116 389.7 44.0 1.6e-116 389.4 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON97369.1 - 1.8e-29 102.5 47.2 2.3e-29 102.2 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease Transp_cyt_pur PF02133.10 EON97370.1 - 3.6e-46 157.6 14.3 4e-46 157.4 9.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3961 PF13106.1 EON97370.1 - 0.052 13.1 0.7 0.13 11.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) DUF2443 PF10398.4 EON97370.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF844 PF05815.6 EON97371.1 - 0.043 12.6 0.1 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Ub-RnfH PF03658.9 EON97371.1 - 0.098 12.5 0.1 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RnfH family Ubiquitin FAA_hydrolase PF01557.13 EON97372.1 - 2.7e-44 151.2 0.0 4.6e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EON97372.1 - 6.2e-27 93.7 0.0 1.2e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Acetyltransf_1 PF00583.19 EON97372.1 - 7.7e-09 35.4 0.4 2.8e-08 33.6 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON97372.1 - 4e-08 33.3 0.0 1.5e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON97372.1 - 2.7e-05 24.2 0.0 6.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON97372.1 - 0.00055 19.6 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EON97372.1 - 0.0016 18.3 0.1 0.0056 16.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EON97372.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-C2H2 PF00096.21 EON97373.1 - 0.1 12.9 1.3 0.54 10.7 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_1 PF07690.11 EON97374.1 - 6.6e-06 25.0 17.1 1.2e-05 24.2 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EON97374.1 - 0.0019 17.6 3.7 1.8 7.9 2.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) DUF912 PF06024.7 EON97374.1 - 0.0051 16.8 0.0 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4118 PF13493.1 EON97374.1 - 9.9 6.4 11.1 4.8 7.4 5.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4118) DUF2621 PF11084.3 EON97375.1 - 0.028 14.1 0.3 0.051 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) OmpH PF03938.9 EON97375.1 - 0.06 13.2 0.6 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 EON97375.1 - 0.74 10.2 7.0 7.3 7.0 1.9 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4404 PF14357.1 EON97375.1 - 1.5 9.2 4.8 1 9.8 1.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Catalase PF00199.14 EON97376.1 - 2.6e-122 408.2 6.2 2.8e-120 401.5 4.3 2.2 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EON97376.1 - 8.5e-13 47.9 0.5 2e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Inhibitor_Mig-6 PF11555.3 EON97376.1 - 0.026 14.8 0.1 0.056 13.8 0.1 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Cellulase PF00150.13 EON97377.1 - 1.2e-40 139.5 0.4 1.3e-35 122.9 0.3 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Peptidase_S10 PF00450.17 EON97378.1 - 6.1e-40 137.6 9.8 2.8e-39 135.4 6.8 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Fungal_lectin PF07938.7 EON97378.1 - 0.062 12.5 0.1 0.089 12.0 0.1 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin GMC_oxred_N PF00732.14 EON97379.1 - 5.5e-54 183.3 0.0 9.9e-54 182.4 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON97379.1 - 3.4e-37 127.9 0.0 5.2e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON97379.1 - 9.3e-07 28.0 0.3 0.0023 16.8 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON97379.1 - 3.7e-05 22.8 0.1 0.00026 20.0 0.3 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON97379.1 - 0.00028 19.9 0.5 0.00041 19.3 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EON97379.1 - 0.0003 20.7 0.0 0.00072 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON97379.1 - 0.0025 17.9 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON97379.1 - 0.018 14.8 0.0 0.04 13.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON97379.1 - 0.049 12.7 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EON97379.1 - 0.2 10.4 0.9 0.4 9.5 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A COesterase PF00135.23 EON97380.1 - 1.1e-87 295.0 3.7 3.2e-81 273.6 0.9 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EON97380.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PTR2 PF00854.16 EON97381.1 - 1.1e-44 152.7 20.0 1.1e-32 113.3 1.5 3.5 1 1 2 3 3 3 3 POT family DUF1616 PF07760.6 EON97381.1 - 0.0069 15.5 6.6 0.4 9.7 3.6 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1616) OPT PF03169.10 EON97382.1 - 2.8e-153 511.6 46.9 3.1e-153 511.5 32.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1352 PF07086.7 EON97382.1 - 5.3 6.6 11.5 1.7 8.2 4.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1352) Sugar_tr PF00083.19 EON97383.1 - 4.7e-37 127.6 19.1 5.3e-37 127.4 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97383.1 - 0.0064 15.2 23.2 0.014 14.0 16.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 EON97384.1 - 1.8e-13 50.1 0.0 4.2e-09 35.7 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON97384.1 - 0.0054 17.1 1.7 0.012 15.9 1.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON97384.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97384.1 - 0.012 15.5 0.2 0.039 13.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON97384.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EON97384.1 - 0.11 11.6 0.4 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EON97384.1 - 0.2 10.7 1.1 0.33 9.9 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain Myosin_tail_1 PF01576.14 EON97385.1 - 1.1e-07 30.0 109.5 2.4e-05 22.2 25.9 4.0 1 1 2 3 3 3 2 Myosin tail CENP-F_leu_zip PF10473.4 EON97385.1 - 3.4e-05 23.7 105.7 0.0019 18.0 14.5 6.7 1 1 6 7 7 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 EON97385.1 - 5.4e-05 21.9 29.5 5.4e-05 21.9 20.4 3.5 1 1 2 3 3 2 1 Protein of unknown function (DUF812) DUF4201 PF13870.1 EON97385.1 - 6.7e-05 22.4 76.0 0.00075 18.9 4.1 6.7 1 1 6 7 7 7 4 Domain of unknown function (DUF4201) CALCOCO1 PF07888.6 EON97385.1 - 0.00031 19.1 25.8 0.00031 19.1 17.9 3.9 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like LPP PF04728.8 EON97385.1 - 0.00086 19.0 38.1 0.0038 16.9 0.3 8.4 4 2 5 9 9 9 3 Lipoprotein leucine-zipper Filament PF00038.16 EON97385.1 - 0.001 18.5 85.7 0.059 12.8 32.8 5.5 1 1 2 3 3 3 1 Intermediate filament protein AAA_13 PF13166.1 EON97385.1 - 0.0013 17.2 25.8 0.0013 17.2 17.9 3.8 1 1 3 4 4 3 3 AAA domain DUF2968 PF11180.3 EON97385.1 - 0.0047 16.3 6.8 0.0047 16.3 4.7 6.9 1 1 5 7 7 5 1 Protein of unknown function (DUF2968) GAS PF13851.1 EON97385.1 - 0.0068 15.6 91.7 0.28 10.3 10.4 5.9 1 1 4 6 6 6 5 Growth-arrest specific micro-tubule binding IncA PF04156.9 EON97385.1 - 0.031 13.8 98.2 0.093 12.3 11.9 5.6 1 1 4 5 5 5 0 IncA protein Viral_P18 PF04521.8 EON97385.1 - 0.077 12.4 0.1 0.077 12.4 0.1 7.2 2 1 6 9 9 8 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1664 PF07889.7 EON97385.1 - 0.2 11.4 56.8 0.02 14.7 2.0 6.3 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EON97385.1 - 0.34 10.0 70.6 0.12 11.5 10.4 5.7 1 1 5 6 6 6 0 Reovirus sigma C capsid protein DUF869 PF05911.6 EON97385.1 - 0.56 8.3 97.0 0.16 10.2 27.9 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Bacillus_HBL PF05791.6 EON97385.1 - 0.95 8.7 58.3 0.017 14.5 4.9 5.6 2 1 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.7 EON97385.1 - 1.7 8.5 47.9 0.092 12.5 2.8 5.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EON97385.1 - 1.8 8.4 100.6 0.24 11.2 5.7 8.3 1 1 5 7 7 7 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.7 EON97385.1 - 3.2 7.7 26.6 2.8 7.9 2.8 7.5 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.7 EON97385.1 - 4 7.2 123.9 0.045 13.4 16.2 5.8 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 EON97385.1 - 5 6.3 101.5 0.17 11.2 15.1 5.5 1 1 5 6 6 6 0 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.3 EON97385.1 - 7.3 6.3 83.6 2.1 8.1 3.0 7.7 1 1 6 8 8 8 0 TATA element modulatory factor 1 TATA binding p450 PF00067.17 EON97386.1 - 7.6e-61 206.0 0.0 9.4e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 EON97387.1 - 3.4e-86 290.0 0.1 1.1e-85 288.3 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Hydantoinase_B PF02538.9 EON97388.1 - 3e-191 636.2 0.0 4.2e-191 635.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EON97388.1 - 1.4e-91 306.6 1.3 5.8e-91 304.5 0.0 2.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EON97388.1 - 1.3e-60 203.9 0.3 5.5e-59 198.6 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region adh_short PF00106.20 EON97390.1 - 6.2e-32 110.8 2.7 6.2e-32 110.8 1.9 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.7 EON97390.1 - 1.4e-31 108.4 0.7 1.4e-31 108.4 0.5 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON97390.1 - 3.7e-24 84.7 0.6 9.6e-24 83.3 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 EON97390.1 - 3.6e-12 46.3 1.4 6.2e-12 45.5 0.9 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.1 EON97390.1 - 2e-05 25.4 0.0 0.00013 22.8 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EON97390.1 - 0.00036 21.0 0.7 0.0007 20.1 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON97390.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EON97390.1 - 0.027 14.5 0.2 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EON97390.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EON97390.1 - 0.031 13.4 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EON97390.1 - 0.036 13.1 0.6 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_23 PF13489.1 EON97390.1 - 0.039 13.6 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EON97390.1 - 0.04 13.3 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CMAS PF02353.15 EON97390.1 - 0.046 12.7 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RmlD_sub_bind PF04321.12 EON97390.1 - 0.11 11.3 0.6 0.75 8.6 0.1 2.1 1 1 1 2 2 2 0 RmlD substrate binding domain PUA PF01472.15 EON97391.1 - 7.2e-13 48.0 0.3 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 PUA domain Sulfatase PF00884.18 EON97392.1 - 3.1e-77 259.7 0.0 3.9e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EON97392.1 - 0.00011 21.6 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EON97392.1 - 0.0027 17.9 0.2 0.13 12.5 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EON97392.1 - 0.23 9.8 0.0 0.41 9.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TPR_11 PF13414.1 EON97393.1 - 1.3e-12 47.1 0.9 4.1e-12 45.5 0.2 2.0 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EON97393.1 - 1.1e-06 28.0 0.1 0.0051 16.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON97393.1 - 5.4e-05 23.0 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EON97393.1 - 9.6e-05 21.8 0.5 0.028 14.0 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DASH_Dad2 PF08654.5 EON97393.1 - 0.012 15.5 0.4 0.037 14.0 0.3 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad2 TPR_7 PF13176.1 EON97393.1 - 0.04 13.7 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EON97393.1 - 0.041 14.0 0.4 0.094 12.8 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EON97393.1 - 0.12 12.2 0.2 0.12 12.2 0.1 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain AAA_23 PF13476.1 EON97393.1 - 0.98 9.7 6.2 1.8 8.8 4.3 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 EON97394.1 - 8.2e-81 271.8 0.0 1e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zeta_toxin PF06414.7 EON97394.1 - 0.075 12.1 0.1 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin OATP PF03137.15 EON97394.1 - 0.13 10.3 0.1 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Arm PF00514.18 EON97396.1 - 1.3e-70 231.0 31.3 3.4e-13 48.8 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EON97396.1 - 8e-24 83.7 13.7 4e-07 30.2 0.3 7.7 3 2 4 7 7 7 6 HEAT repeats HEAT PF02985.17 EON97396.1 - 9.1e-19 65.8 17.4 0.031 14.3 0.1 9.6 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 EON97396.1 - 6.8e-17 61.4 14.5 0.00085 19.7 0.2 8.5 4 1 5 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 EON97396.1 - 2.5e-12 46.4 8.2 0.00087 18.4 0.1 3.5 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 EON97396.1 - 5.6e-12 44.7 10.3 1.9e-07 29.7 0.3 3.2 2 1 2 4 4 4 2 Adaptin N terminal region KAP PF05804.7 EON97396.1 - 1e-10 40.2 0.6 2.2e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EON97396.1 - 5.1e-09 35.6 2.5 0.0032 16.6 0.1 3.8 2 1 1 3 3 3 2 V-ATPase subunit H DUF908 PF06012.7 EON97396.1 - 0.00018 20.9 1.6 0.3 10.3 0.1 3.8 2 1 2 4 4 4 1 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 EON97396.1 - 0.00072 19.8 6.0 6.1 7.6 0.3 6.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF2454 PF10521.4 EON97396.1 - 0.00079 18.5 1.1 0.0062 15.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) PUL PF08324.6 EON97396.1 - 0.0018 17.1 2.4 0.0056 15.5 0.5 2.5 2 0 0 2 2 2 1 PUL domain Vac14_Fab1_bd PF12755.2 EON97396.1 - 0.018 15.4 0.2 1.9 8.8 0.0 3.6 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Vpu PF00558.14 EON97396.1 - 0.041 13.4 0.4 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 Vpu protein Fringe PF02434.11 EON97397.1 - 5e-07 29.1 1.3 8.3e-06 25.2 0.9 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EON97397.1 - 0.0056 16.3 3.0 0.0056 16.3 2.0 1.9 2 0 0 2 2 2 1 PAN domain AAA PF00004.24 EON97398.1 - 7.3e-40 136.2 0.0 1.7e-39 135.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EON97398.1 - 0.00016 21.7 0.1 0.012 15.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EON97398.1 - 0.00018 21.2 0.6 0.00073 19.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EON97398.1 - 0.00028 20.0 0.0 0.0006 18.9 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EON97398.1 - 0.00052 20.1 0.6 0.018 15.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 EON97398.1 - 0.0012 18.8 0.0 0.0085 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EON97398.1 - 0.0045 16.2 0.3 0.042 13.0 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EON97398.1 - 0.0064 15.6 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EON97398.1 - 0.0072 15.2 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EON97398.1 - 0.0099 15.7 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON97398.1 - 0.013 16.2 1.0 0.08 13.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EON97398.1 - 0.017 14.8 0.4 0.042 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EON97398.1 - 0.022 14.2 0.1 0.045 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EON97398.1 - 0.039 13.3 1.6 0.3 10.4 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EON97398.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EON97398.1 - 0.24 10.9 1.6 0.6 9.6 0.0 2.3 2 2 1 3 3 3 0 AAA domain SAF PF08666.7 EON97399.1 - 2.5e-08 34.1 0.0 4.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 SAF domain GFO_IDH_MocA PF01408.17 EON97399.1 - 4.8e-05 23.8 0.0 0.00017 22.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EON97399.1 - 0.00017 21.9 0.0 0.00063 20.1 0.0 2.0 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EON97399.1 - 0.011 15.6 0.1 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Aminotran_3 PF00202.16 EON97400.1 - 3.5e-26 91.8 0.1 4.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3783 PF12646.2 EON97400.1 - 0.11 12.2 0.6 0.26 11.0 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Glyco_transf_8 PF01501.15 EON97401.1 - 2.9e-36 125.0 0.0 5.7e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EON97401.1 - 0.0038 16.6 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative COMPASS-Shg1 PF05205.7 EON97403.1 - 5.1e-26 91.0 0.1 1.6e-25 89.4 0.1 1.9 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Chitin_synth_2 PF03142.10 EON97404.1 - 6.4e-233 773.9 0.1 8.5e-233 773.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EON97404.1 - 1.6e-63 214.8 0.0 6e-63 212.9 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EON97404.1 - 4.8e-18 64.7 0.0 8.1e-12 44.7 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EON97404.1 - 6.2e-17 61.9 2.8 6.2e-17 61.9 2.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON97404.1 - 1.2e-14 54.7 0.1 5.2e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EON97404.1 - 2.4e-14 52.8 1.2 4.7e-13 48.6 1.2 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EON97404.1 - 4.7e-07 29.2 0.0 9e-06 25.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EON97404.1 - 0.00043 20.0 0.0 0.027 14.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Homeobox PF00046.24 EON97405.1 - 1.3e-19 69.5 4.4 2.5e-19 68.6 3.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EON97405.1 - 0.00024 20.7 0.5 0.00066 19.3 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ish1 PF10281.4 EON97406.1 - 9.1e-83 271.8 24.6 3.8e-13 49.2 0.0 8.7 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EON97406.1 - 3.3e-11 42.4 0.0 0.11 12.0 0.0 7.9 9 0 0 9 9 9 3 SAP domain Slx4 PF09494.5 EON97406.1 - 9.1e-08 31.7 3.6 14 5.5 0.0 6.6 7 0 0 7 7 7 3 Slx4 endonuclease HeH PF12949.2 EON97406.1 - 3.1e-07 29.8 1.4 5.9 6.5 0.0 7.6 8 1 0 8 8 8 2 HeH/LEM domain APC2 PF08672.6 EON97406.1 - 0.00011 22.3 5.2 14 6.0 0.0 6.9 8 0 0 8 8 8 1 Anaphase promoting complex (APC) subunit 2 SAM_2 PF07647.12 EON97406.1 - 0.29 11.0 2.4 2.3 8.1 0.1 3.4 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) DUF1470 PF07336.6 EON97406.1 - 3 8.1 9.4 12 6.1 0.2 4.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1470) F-box PF00646.28 EON97407.1 - 3.8e-07 29.6 0.1 1.1e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EON97407.1 - 1e-06 28.3 0.1 2.2e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EON97407.1 - 0.0011 18.6 0.1 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like domain DUF4140 PF13600.1 EON97407.1 - 0.16 12.4 2.6 0.68 10.4 1.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EON97407.1 - 0.16 11.9 9.2 0.035 14.1 3.1 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YqzE PF14038.1 EON97407.1 - 0.46 10.2 2.3 1.5 8.6 0.0 2.9 4 0 0 4 4 4 0 YqzE-like protein Pkinase PF00069.20 EON97408.1 - 8.6e-57 192.2 0.4 5.2e-40 137.2 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EON97408.1 - 2.8e-27 95.4 0.1 3.5e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EON97408.1 - 6e-05 22.1 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON97408.1 - 0.00011 22.0 0.2 0.013 15.2 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EON97408.1 - 0.00032 19.8 0.1 0.00086 18.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EON97408.1 - 0.014 15.8 0.1 0.037 14.5 0.1 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EON97408.1 - 0.027 13.2 0.1 0.043 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EON97408.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 WaaY PF06176.6 EON97408.1 - 0.07 12.3 0.7 0.11 11.6 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EON97408.1 - 0.074 12.3 1.7 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family RPAP3_C PF13877.1 EON97409.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Solute_trans_a PF03619.11 EON97410.1 - 4.7e-104 347.5 8.9 5.8e-104 347.2 6.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BCLP PF12304.3 EON97410.1 - 0.16 11.3 1.0 0.26 10.6 0.7 1.3 1 0 0 1 1 1 0 Beta-casein like protein E1_DerP2_DerF2 PF02221.10 EON97411.1 - 6.4e-24 84.7 0.2 7.5e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EON97411.1 - 0.0052 16.8 0.1 0.028 14.4 0.1 1.9 1 1 0 1 1 1 1 ML-like domain ABM PF03992.11 EON97412.1 - 0.006 16.5 3.6 0.26 11.3 0.1 3.2 3 1 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Cu-oxidase_2 PF07731.9 EON97413.1 - 1.6e-23 82.7 0.7 2.6e-23 82.0 0.5 1.4 1 0 0 1 1 1 1 Multicopper oxidase Hemerythrin PF01814.18 EON97414.1 - 1.8e-08 34.6 0.2 2.4e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ORC6 PF05460.8 EON97415.1 - 0.0044 16.1 3.2 0.0048 16.0 2.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) RR_TM4-6 PF06459.7 EON97415.1 - 0.67 9.7 6.3 0.72 9.7 4.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ebola_NP PF05505.7 EON97415.1 - 0.9 7.5 5.9 1.1 7.2 4.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein CBFD_NFYB_HMF PF00808.18 EON97416.1 - 2.8e-09 36.9 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fungal_trans PF04082.13 EON97417.1 - 9.2e-32 109.9 0.3 2e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON97417.1 - 1.2e-10 41.0 11.5 2.3e-10 40.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 EON97417.1 - 0.012 14.1 0.0 0.029 12.8 0.0 1.6 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Apt1 PF10351.4 EON97417.1 - 2.1 7.1 6.8 3.3 6.4 4.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NT-C2 PF10358.4 EON97418.1 - 1.8 8.0 8.2 0.49 9.8 0.6 2.0 1 1 1 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Glyco_hydro_92 PF07971.7 EON97419.1 - 2.5e-86 290.3 2.6 7.3e-65 219.5 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_20 PF00728.17 EON97420.1 - 4.6e-93 312.1 0.6 5.9e-93 311.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EON97420.1 - 2.6e-23 83.0 0.1 4.7e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EON97420.1 - 5.4e-05 23.7 0.1 0.00011 22.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PGI PF00342.14 EON97421.1 - 2.9e-206 685.5 0.2 3.3e-206 685.4 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MFS_1 PF07690.11 EON97422.1 - 1.9e-43 148.5 44.9 3.3e-43 147.7 31.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97422.1 - 1.8e-17 63.0 9.1 1.8e-17 63.0 6.3 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4516 PF14990.1 EON97422.1 - 0.39 10.3 2.1 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Hydantoinase_B PF02538.9 EON97423.1 - 2.1e-166 554.2 0.4 3.5e-104 348.9 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EON97423.1 - 3.8e-95 318.3 0.0 4.8e-93 311.4 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EON97423.1 - 4.8e-53 179.2 0.5 4.2e-51 172.9 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Nipped-B_C PF12830.2 EON97424.1 - 2.2e-46 157.8 3.9 2.3e-45 154.5 1.6 2.8 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EON97424.1 - 3.3e-12 46.0 8.0 5.7e-12 45.3 0.3 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EON97424.1 - 2e-08 33.6 1.0 0.0063 16.5 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 EON97424.1 - 1.2e-06 27.1 1.2 2.4e-05 22.8 0.0 3.1 4 0 0 4 4 4 1 Adaptin N terminal region HEAT_2 PF13646.1 EON97424.1 - 0.00068 19.8 0.5 0.17 12.1 0.1 3.9 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EON97424.1 - 0.0017 18.2 0.0 0.35 10.6 0.0 2.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EON97424.1 - 0.002 16.9 0.7 0.0056 15.4 0.5 1.8 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal DUF3554 PF12074.3 EON97424.1 - 0.004 16.6 0.0 5.6 6.2 0.0 4.1 3 2 1 4 4 4 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 EON97424.1 - 0.016 15.7 0.1 3 8.4 0.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat GST_C PF00043.20 EON97425.1 - 0.00021 21.2 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EON97425.1 - 0.00037 20.3 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EON97425.1 - 0.0037 17.4 0.1 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EON97425.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1516 PF07457.6 EON97426.1 - 0.034 14.2 1.4 0.056 13.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) HD_5 PF13487.1 EON97426.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 HD domain FMN_dh PF01070.13 EON97427.1 - 6.6e-120 400.2 0.1 8.4e-120 399.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EON97427.1 - 8.6e-19 67.1 0.0 3.7e-08 33.0 0.0 2.4 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EON97427.1 - 3e-08 32.9 0.0 4.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EON97427.1 - 0.00024 20.1 0.3 0.0013 17.6 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EON97427.1 - 0.00047 19.4 0.1 0.00078 18.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EON97427.1 - 0.0038 16.5 0.8 0.27 10.4 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EON97427.1 - 0.021 13.9 0.1 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG ECH_C PF13766.1 EON97428.1 - 3.6e-37 127.1 0.1 8.7e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EON97428.1 - 7e-27 94.1 0.0 1.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GCV_H PF01597.14 EON97429.1 - 9.1e-34 115.7 0.9 1.1e-33 115.5 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Glyco_transf_17 PF04724.8 EON97430.1 - 3e-41 141.6 1.6 6.9e-41 140.4 1.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 BCDHK_Adom3 PF10436.4 EON97432.1 - 4.6e-42 143.3 0.0 6.8e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EON97432.1 - 3.6e-18 65.3 0.0 2.1e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EON97432.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ACT_7 PF13840.1 EON97434.1 - 2.4e-06 26.9 0.0 2.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ACT domain LpxD PF04613.9 EON97434.1 - 0.055 13.0 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD TIP120 PF08623.5 EON97435.1 - 1.5e-66 223.1 8.7 2.1e-62 209.6 0.0 5.1 3 1 2 5 5 5 3 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EON97435.1 - 1.2e-16 60.7 26.9 0.00054 20.1 0.2 9.5 8 2 2 10 10 10 6 HEAT repeats HEAT PF02985.17 EON97435.1 - 2.2e-11 42.7 28.6 0.19 11.9 0.1 11.8 13 0 0 13 13 12 4 HEAT repeat HEAT_EZ PF13513.1 EON97435.1 - 3.2e-08 33.8 27.9 0.071 13.6 0.3 11.9 11 4 3 14 14 13 3 HEAT-like repeat CLASP_N PF12348.3 EON97435.1 - 1.5e-07 30.9 1.6 0.72 9.1 0.0 4.9 3 1 2 5 5 5 3 CLASP N terminal DUF2435 PF10363.4 EON97435.1 - 3.4e-07 30.0 9.9 0.25 11.2 0.1 7.1 8 0 0 8 8 8 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EON97435.1 - 8.3e-05 22.5 13.6 0.22 11.3 0.9 5.8 5 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.1 EON97435.1 - 0.015 15.2 0.2 0.81 9.6 0.0 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF720 PF05302.6 EON97435.1 - 0.022 14.5 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF720) MMS19_C PF12460.3 EON97435.1 - 0.094 11.4 11.4 11 4.6 0.3 5.4 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal ATP-cone PF03477.11 EON97435.1 - 0.12 12.8 2.1 4.4 7.8 0.0 3.9 4 0 0 4 4 4 0 ATP cone domain Nucleoplasmin PF03066.10 EON97435.1 - 1.7 8.1 6.6 4.3 6.8 4.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin adh_short PF00106.20 EON97436.1 - 9.4e-11 41.9 0.1 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97436.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON97436.1 - 0.00062 19.5 0.0 0.00076 19.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EON97436.1 - 0.0059 15.5 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EON97436.1 - 0.0065 16.1 0.1 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IF-2B PF01008.12 EON97437.1 - 6.4e-45 153.3 0.1 1.6e-44 152.0 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S18 PF01084.15 EON97437.1 - 0.099 12.5 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S18 CDC45 PF02724.9 EON97438.1 - 5.2e-87 292.3 23.5 5.5e-58 196.4 10.7 3.8 1 1 1 2 2 2 2 CDC45-like protein Cwf_Cwc_15 PF04889.7 EON97438.1 - 0.015 15.0 12.4 0.027 14.2 8.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM60A PF15396.1 EON97438.1 - 0.04 13.6 1.0 0.058 13.1 0.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2457 PF10446.4 EON97438.1 - 0.11 11.2 17.3 0.17 10.5 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop25 PF09805.4 EON97438.1 - 0.15 12.1 15.4 0.23 11.5 10.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Daxx PF03344.10 EON97438.1 - 0.25 9.7 9.7 0.33 9.3 6.7 1.1 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 EON97438.1 - 1.5 7.6 8.6 2.2 7.0 6.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 EON97438.1 - 2.5 7.0 18.3 3.3 6.6 12.7 1.1 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 EON97438.1 - 2.8 7.9 12.1 5 7.1 8.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3129 PF11327.3 EON97439.1 - 1.8e-58 197.3 9.8 2.3e-58 197.0 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) HemeBinding_Shp PF11545.3 EON97439.1 - 0.048 13.4 1.1 0.35 10.6 0.2 2.1 2 0 0 2 2 2 0 Cell surface heme-binding protein Shp adh_short_C2 PF13561.1 EON97440.1 - 6.5e-12 45.7 0.0 7.6e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON97440.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldo_ket_red PF00248.16 EON97441.1 - 7.1e-67 225.1 0.0 9.4e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pantoate_ligase PF02569.10 EON97441.1 - 0.099 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Dak1 PF02733.12 EON97442.1 - 6.5e-108 360.1 7.7 9e-108 359.6 5.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EON97442.1 - 4.6e-42 143.6 0.1 1e-41 142.5 0.0 1.6 1 0 0 1 1 1 1 DAK2 domain CLASP_N PF12348.3 EON97443.1 - 1.7e-129 429.9 0.8 2.7e-85 285.3 0.0 2.4 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EON97443.1 - 1.4e-06 27.8 0.1 0.47 10.6 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EON97443.1 - 0.0001 22.5 1.0 0.076 13.3 0.2 4.9 3 2 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EON97443.1 - 0.0041 17.5 0.1 1.8 9.1 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 EON97443.1 - 0.011 14.1 0.0 0.058 11.6 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region DUF2999 PF11212.3 EON97443.1 - 0.015 15.3 0.1 0.085 12.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Cnd1 PF12717.2 EON97443.1 - 0.12 12.2 0.0 0.64 9.8 0.0 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AMP-binding PF00501.23 EON97444.1 - 4.7e-87 292.0 0.0 6.9e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON97444.1 - 0.011 16.6 0.2 0.04 14.8 0.1 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Acyl_transf_1 PF00698.16 EON97445.1 - 6.2e-82 275.4 0.0 6.6e-79 265.5 0.0 3.3 4 0 0 4 4 4 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EON97445.1 - 5.6e-40 135.5 0.0 1.5e-39 134.1 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EON97445.1 - 4.5e-30 103.2 1.6 8.1e-30 102.3 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EON97445.1 - 3.9e-21 75.2 0.1 1.2e-20 73.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EON97445.1 - 6.9e-06 25.4 0.3 0.023 13.8 0.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase PCIF1_WW PF12237.3 EON97445.1 - 0.24 10.7 0.0 0.92 8.7 0.0 1.8 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain DNA_pol_E_B PF04042.11 EON97446.1 - 4.8e-53 179.5 0.0 6.2e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CDI PF02234.14 EON97446.1 - 0.0069 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor RCC1 PF00415.13 EON97448.1 - 6.2e-54 180.0 4.0 8.7e-10 38.6 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EON97448.1 - 1.6e-29 100.8 35.0 2.9e-09 36.2 0.6 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EON97448.1 - 0.073 12.5 0.0 18 4.9 0.0 3.5 3 0 0 3 3 3 0 Putative carbohydrate binding domain Arylsulfotran_2 PF14269.1 EON97448.1 - 0.1 11.7 0.2 0.43 9.6 0.1 2.0 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) DHDPS PF00701.17 EON97449.1 - 6.6e-32 110.2 0.0 7.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peptidase_M19 PF01244.16 EON97450.1 - 1e-92 310.5 0.0 1.2e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Acetyltransf_3 PF13302.1 EON97452.1 - 4.4e-18 65.8 0.0 5.8e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EON97452.1 - 9.1e-06 25.6 0.0 0.0093 15.8 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON97452.1 - 0.00015 21.4 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.1 EON97452.1 - 0.00017 21.5 0.1 0.075 12.9 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON97452.1 - 0.0065 16.4 0.0 0.077 13.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 EON97453.1 - 1.5e-64 217.3 0.1 2.2e-64 216.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop52 PF05997.7 EON97454.1 - 3.3e-48 163.9 1.1 8.9e-47 159.3 0.8 2.0 1 1 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EON97454.1 - 0.049 13.3 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DEAD PF00270.24 EON97455.1 - 1e-39 135.7 0.0 1.7e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON97455.1 - 7.2e-27 93.0 0.0 1.5e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON97455.1 - 0.0076 16.0 0.0 0.043 13.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GLTP PF08718.6 EON97456.1 - 4.7e-47 159.7 0.0 8.1e-47 158.9 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Ribosomal_L4 PF00573.17 EON97457.1 - 2.7e-48 163.8 0.0 3.6e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PALP PF00291.20 EON97458.1 - 1.2e-29 103.5 0.2 1.4e-29 103.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EON97458.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 LytB protein Ank_2 PF12796.2 EON97459.1 - 2.7e-58 194.2 3.1 5.4e-11 42.6 0.0 8.8 5 3 4 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EON97459.1 - 8.8e-47 154.6 13.9 1.1e-06 28.1 0.1 13.5 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 EON97459.1 - 5.5e-43 144.6 15.5 2.2e-05 24.8 0.0 11.4 9 3 3 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON97459.1 - 5.1e-39 128.3 13.0 2.7e-06 27.0 0.1 13.9 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.1 EON97459.1 - 1.3e-28 98.3 20.3 1.2e-05 25.3 0.1 9.7 9 2 1 10 10 10 6 Ankyrin repeats (many copies) F-box-like PF12937.2 EON97459.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Esterase PF00756.15 EON97459.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative esterase DUF4210 PF13915.1 EON97460.1 - 5e-26 90.7 0.1 1e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EON97460.1 - 3.9e-22 77.8 0.7 1.1e-21 76.4 0.5 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Hydrophobin_2 PF06766.6 EON97461.1 - 2.7e-26 91.0 8.8 3.4e-26 90.7 6.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin zf-C3Hc3H PF13891.1 EON97461.1 - 0.47 10.5 3.4 3.3 7.8 0.3 2.2 1 1 0 2 2 2 0 Potential DNA-binding domain Ribosomal_S13 PF00416.17 EON97462.1 - 6.4e-21 74.8 0.1 7.2e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 UBA PF00627.26 EON97462.1 - 0.12 12.2 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain PRP1_N PF06424.7 EON97463.1 - 0.018 15.3 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal MFS_1 PF07690.11 EON97464.1 - 5.7e-37 127.2 27.1 5.7e-37 127.2 18.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 EON97464.1 - 0.052 13.2 0.8 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TauD PF02668.11 EON97465.1 - 1.6e-20 73.8 0.0 2e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F_bP_aldolase PF01116.15 EON97466.1 - 1.2e-84 283.7 0.1 1.4e-84 283.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AA_permease PF00324.16 EON97467.1 - 1.6e-25 89.4 25.0 1.7e-23 82.7 14.8 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EON97467.1 - 1.6e-15 56.6 17.0 2e-15 56.3 11.8 1.1 1 0 0 1 1 1 1 Amino acid permease BaxI_1 PF12811.2 EON97467.1 - 0.0018 17.4 0.1 0.0018 17.4 0.1 1.6 2 0 0 2 2 2 1 Bax inhibitor 1 like ORC2 PF04084.9 EON97468.1 - 5.1e-87 291.7 0.0 6.1e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 OST-HTH PF12872.2 EON97468.1 - 0.066 13.0 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 0 OST-HTH/LOTUS domain NMD3 PF04981.8 EON97469.1 - 2.7e-72 242.7 1.4 4.4e-72 242.0 0.9 1.3 1 0 0 1 1 1 1 NMD3 family DUF4355 PF14265.1 EON97469.1 - 0.0073 16.2 8.7 0.015 15.2 6.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) DUF35_N PF12172.3 EON97469.1 - 0.011 15.6 0.7 0.36 10.7 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 EON97469.1 - 2.7 7.9 5.3 12 5.8 1.9 2.3 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 EON97469.1 - 5.9 6.7 8.7 38 4.1 4.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon Mit_ribos_Mrp51 PF11709.3 EON97470.1 - 4.5e-56 190.3 0.0 5.3e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAD_binding_3 PF01494.14 EON97471.1 - 8e-15 54.7 0.3 2.6e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON97471.1 - 7.1e-08 31.7 0.1 0.0036 16.2 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EON97471.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97471.1 - 8.9e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON97471.1 - 0.00043 20.2 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON97471.1 - 0.0057 16.4 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EON97471.1 - 0.0086 14.5 0.0 0.083 11.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EON97471.1 - 0.0087 14.9 0.4 0.05 12.4 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EON97471.1 - 0.029 13.2 0.4 0.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EON97471.1 - 0.033 14.6 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EON97471.1 - 0.11 11.0 0.2 0.94 8.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EON97471.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TRI12 PF06609.8 EON97472.1 - 1.7e-10 39.7 3.5 2.1e-10 39.4 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON97472.1 - 5.8e-05 21.9 15.0 0.00099 17.9 10.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily BacA PF02673.13 EON97472.1 - 0.0019 17.4 0.2 0.0037 16.4 0.0 1.4 1 1 1 2 2 2 1 Bacitracin resistance protein BacA DUF2976 PF11190.3 EON97472.1 - 0.06 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF1673 PF07895.6 EON97472.1 - 4.3 6.8 5.9 11 5.4 2.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) FAD_binding_3 PF01494.14 EON97473.1 - 2.8e-22 79.2 0.3 5e-22 78.4 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EON97473.1 - 8.5e-13 47.9 2.2 1.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON97473.1 - 3.7e-07 30.0 3.4 9.7e-07 28.7 2.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EON97473.1 - 5.1e-07 28.8 0.9 0.0024 16.7 4.6 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EON97473.1 - 7.7e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON97473.1 - 2e-05 24.5 0.9 6.5e-05 22.8 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON97473.1 - 2.5e-05 24.5 2.3 0.00016 22.0 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON97473.1 - 4.7e-05 22.0 3.1 0.00013 20.5 2.2 1.7 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EON97473.1 - 5.2e-05 22.5 1.7 9.6e-05 21.6 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EON97473.1 - 7e-05 22.0 4.3 0.027 13.5 1.7 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EON97473.1 - 0.00012 20.8 5.0 0.00056 18.6 1.8 2.4 3 0 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 EON97473.1 - 0.0041 16.0 1.7 0.0063 15.4 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EON97473.1 - 0.017 14.2 0.9 0.034 13.2 0.6 1.4 1 0 0 1 1 1 0 Thi4 family Rossmann-like PF10727.4 EON97473.1 - 0.059 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.7 EON97473.1 - 0.12 11.2 2.8 0.65 8.8 2.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EON97473.1 - 0.2 11.4 4.3 3.4 7.4 0.6 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EON97473.1 - 0.24 10.9 1.3 0.51 9.8 0.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Kelch_4 PF13418.1 EON97474.1 - 1.7e-11 43.7 6.3 0.00048 19.8 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EON97474.1 - 1.5e-10 40.8 10.1 5.5e-08 32.5 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EON97474.1 - 4.2e-08 33.1 22.2 0.00063 19.8 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EON97474.1 - 1.1e-05 25.3 9.6 0.25 11.5 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EON97474.1 - 0.078 12.5 6.5 2.5 7.7 0.1 4.3 4 0 0 4 4 4 0 Kelch motif GMC_oxred_C PF05199.8 EON97475.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Fungal_trans_2 PF11951.3 EON97476.1 - 3e-05 22.7 0.1 4.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON97476.1 - 0.00019 21.2 2.5 0.00037 20.3 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transglut_core PF01841.14 EON97477.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily CoA_transf_3 PF02515.12 EON97478.1 - 2.1e-57 193.4 0.0 3.4e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III PPR_2 PF13041.1 EON97479.1 - 2.5e-46 155.4 9.1 2.2e-09 37.1 0.0 14.1 10 4 8 18 18 18 11 PPR repeat family PPR PF01535.15 EON97479.1 - 1.3e-23 81.2 27.1 0.00032 20.4 0.0 13.7 18 0 0 18 18 18 6 PPR repeat PPR_3 PF13812.1 EON97479.1 - 1.5e-22 77.9 33.7 0.00084 19.4 0.0 16.5 21 0 0 21 21 21 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EON97479.1 - 1.8e-22 78.4 3.1 1.8e-08 33.6 0.0 10.3 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EON97479.1 - 2.1e-05 24.6 0.0 0.001 19.1 0.0 3.5 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EON97479.1 - 0.049 12.9 0.6 4.2 6.7 0.1 3.7 3 1 1 4 4 4 0 Mitochondrial ATPase expression ATP-synt_F PF01990.12 EON97480.1 - 1.1e-32 112.3 0.0 1.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MTHFR PF02219.12 EON97481.1 - 5.7e-114 380.0 0.0 1.6e-113 378.5 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Sec7 PF01369.15 EON97481.1 - 0.2 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Sec7 domain Glyco_hydro_28 PF00295.12 EON97482.1 - 4.1e-22 78.5 13.1 8.6e-21 74.2 9.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.8 EON97482.1 - 0.11 11.6 7.9 0.13 11.3 5.4 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 EON97482.1 - 1.9 8.2 13.7 4.3 7.0 9.5 1.7 1 1 0 1 1 1 0 Right handed beta helix region Pyr_redox_3 PF13738.1 EON97483.1 - 1.1e-22 81.1 0.0 2.1e-21 76.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON97483.1 - 2.5e-16 59.0 0.0 8.5e-13 47.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EON97483.1 - 9.7e-12 45.1 0.0 1.3e-08 35.0 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON97483.1 - 4.5e-09 35.6 0.2 2.6e-07 29.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EON97483.1 - 2.7e-05 24.4 0.1 0.19 12.1 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97483.1 - 2.8e-05 24.0 0.0 0.00027 20.9 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EON97483.1 - 0.00057 19.0 0.0 0.19 10.7 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain TrkA_N PF02254.13 EON97483.1 - 0.0072 16.3 0.2 3.3 7.7 0.1 2.7 3 0 0 3 3 3 1 TrkA-N domain 3HCDH_N PF02737.13 EON97483.1 - 0.018 14.7 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cuticle_1 PF08140.6 EON97483.1 - 0.04 13.7 0.1 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Mur_ligase PF01225.20 EON97483.1 - 0.04 13.9 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain IlvN PF07991.7 EON97483.1 - 0.048 13.0 0.1 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EON97483.1 - 0.05 12.7 0.0 0.82 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EON97483.1 - 0.064 13.0 0.2 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EON97483.1 - 0.078 11.8 0.0 10 4.8 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FCH PF00611.18 EON97484.1 - 7e-18 64.6 1.4 8e-16 58.0 0.0 3.8 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EON97484.1 - 4.4e-14 51.9 0.0 9.3e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Med4 PF10018.4 EON97484.1 - 6.1e-05 22.4 0.2 6.1e-05 22.4 0.1 2.3 2 1 1 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 KIP1 PF07765.7 EON97484.1 - 0.007 16.1 0.4 1.4 8.8 0.0 3.5 3 0 0 3 3 3 1 KIP1-like protein Sipho_Gp157 PF05565.6 EON97484.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.6 3 0 0 3 3 3 0 Siphovirus Gp157 TMF_DNA_bd PF12329.3 EON97484.1 - 5.2 6.9 8.4 3.5 7.5 0.7 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PBP PF01161.15 EON97485.1 - 7.9e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cyclase PF04199.8 EON97486.1 - 8.5e-15 54.8 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Methyltransf_23 PF13489.1 EON97487.1 - 9.9e-20 70.8 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON97487.1 - 9.6e-13 48.4 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON97487.1 - 1.7e-08 35.0 0.0 4.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON97487.1 - 2e-08 33.9 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EON97487.1 - 1.8e-07 31.4 0.0 4.6e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON97487.1 - 2.6e-07 31.0 0.0 4.4e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON97487.1 - 1.2e-06 27.8 0.0 0.022 13.8 0.0 2.4 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EON97487.1 - 0.00028 20.1 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EON97487.1 - 0.0004 20.3 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON97487.1 - 0.0039 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EON97487.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 EON97487.1 - 0.011 15.2 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EON97487.1 - 0.014 15.3 0.1 0.029 14.3 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.14 EON97487.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EON97487.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_32C PF08244.7 EON97488.1 - 2e-18 66.5 0.3 3.5e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 EON97488.1 - 5.9e-17 61.9 0.0 1.2e-16 61.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_32 PF13679.1 EON97489.1 - 5.9e-20 71.3 0.0 1.5e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 EON97490.1 - 5.5e-32 110.8 25.9 5.5e-32 110.8 17.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SoxG PF04268.7 EON97491.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Sugar_tr PF00083.19 EON97492.1 - 2.1e-82 277.1 27.7 1.2e-66 225.1 7.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON97492.1 - 1.2e-18 66.9 36.9 3.3e-09 35.9 1.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 EON97493.1 - 2.8e-38 131.5 49.0 3.4e-36 124.6 34.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97493.1 - 2.1e-11 43.0 10.3 2.1e-11 43.0 7.2 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EON97493.1 - 4.2e-10 38.4 22.0 6.1e-10 37.9 15.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EON97493.1 - 0.0048 15.0 5.5 0.0082 14.3 3.8 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.3 EON97493.1 - 0.15 10.4 36.5 0.061 11.7 11.8 3.1 1 1 2 3 3 3 0 Vacuole effluxer Atg22 like Aldo_ket_red PF00248.16 EON97494.1 - 1.9e-48 164.7 0.0 2.2e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.17 EON97495.1 - 0.00037 20.5 1.1 0.014 15.5 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Sugar_tr PF00083.19 EON97496.1 - 3.4e-19 68.7 4.7 2.6e-18 65.8 0.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON97496.1 - 4.9e-18 64.9 6.1 2.9e-16 59.1 2.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON97496.1 - 0.0066 14.8 5.9 0.098 11.0 4.9 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein Pex2_Pex12 PF04757.9 EON97497.1 - 3.4e-56 190.2 5.3 4.5e-56 189.8 3.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EON97497.1 - 3.6e-05 23.7 3.1 6.3e-05 22.9 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EON97497.1 - 0.0014 18.4 1.8 0.0023 17.7 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EON97497.1 - 0.011 15.6 2.0 0.019 14.8 1.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EON97497.1 - 0.016 14.8 1.1 0.024 14.2 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON97497.1 - 0.2 11.3 3.3 0.36 10.5 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_76 PF03663.9 EON97498.1 - 1.6e-149 498.3 17.1 1.8e-149 498.1 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EON97498.1 - 0.022 13.7 3.6 0.35 9.8 0.1 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 RNA_lig_T4_1 PF09511.5 EON97499.1 - 1e-80 270.3 0.0 1.9e-80 269.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EON97499.1 - 4.1e-54 182.9 0.1 9e-54 181.8 0.1 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EON97499.1 - 7.8e-48 162.9 0.4 1.3e-47 162.1 0.2 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.1 EON97499.1 - 0.036 14.3 0.1 0.21 11.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Peptidase_M41 PF01434.13 EON97500.1 - 3.6e-76 255.3 0.0 5.7e-76 254.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EON97500.1 - 1.1e-43 148.5 0.0 2.7e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EON97500.1 - 1.1e-08 35.2 0.0 2.5e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 EON97500.1 - 0.00061 19.9 0.2 0.095 12.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EON97500.1 - 0.0022 17.7 0.0 0.0078 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EON97500.1 - 0.004 17.9 0.0 0.014 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EON97500.1 - 0.0048 15.6 0.0 0.0084 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EON97500.1 - 0.0052 16.5 0.5 0.018 14.7 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EON97500.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EON97500.1 - 0.015 14.7 0.1 0.048 13.0 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EON97500.1 - 0.016 15.1 0.5 0.14 12.1 0.1 2.5 2 1 1 3 3 3 0 AAA ATPase domain AAA_2 PF07724.9 EON97500.1 - 0.022 14.6 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EON97500.1 - 0.023 14.0 0.8 0.13 11.6 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EON97500.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EON97500.1 - 0.099 12.6 0.1 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EON97500.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Inhibitor_I78 PF11720.3 EON97501.1 - 2.8e-12 46.1 0.0 3.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EON97501.1 - 0.0046 17.0 0.0 0.0067 16.5 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family Ras PF00071.17 EON97502.1 - 9.3e-32 109.6 0.1 1.1e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON97502.1 - 3.8e-21 75.8 0.1 2.1e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EON97502.1 - 1.1e-06 27.9 0.1 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EON97502.1 - 4.4e-05 22.7 0.1 5.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EON97502.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 EON97502.1 - 0.06 12.0 0.2 3.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EON97502.1 - 0.07 11.7 0.4 0.16 10.6 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit Sec5 PF15469.1 EON97504.1 - 1e-36 126.4 0.1 8.3e-36 123.4 0.0 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 EON97504.1 - 7.8e-06 25.6 0.6 0.00019 21.1 0.0 3.1 2 0 0 2 2 2 1 Vps51/Vps67 DUF2642 PF10842.3 EON97504.1 - 0.31 10.5 1.5 0.5 9.8 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2642) GATA PF00320.22 EON97505.1 - 3.3e-05 23.1 6.3 0.0051 16.1 1.3 2.5 2 0 0 2 2 2 2 GATA zinc finger Flavin_Reduct PF01613.13 EON97506.1 - 1.9e-21 76.5 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_3 PF00933.16 EON97508.1 - 5.4e-46 156.9 0.0 7e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain UPF0086 PF01868.11 EON97510.1 - 2.1e-24 84.9 0.2 3e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 AAA_23 PF13476.1 EON97511.1 - 0.0032 17.8 1.8 0.006 16.9 1.2 1.6 1 0 0 1 1 1 1 AAA domain GAGA_bind PF06217.7 EON97511.1 - 0.15 12.0 9.7 0.22 11.4 6.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PBP_sp32 PF07222.7 EON97511.1 - 0.26 10.4 16.6 1.5 7.9 10.8 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 CAF-1_p150 PF11600.3 EON97511.1 - 0.81 9.0 42.6 8 5.7 29.7 2.1 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 EON97511.1 - 0.92 9.2 8.4 1.9 8.2 5.8 1.5 1 0 0 1 1 1 0 DDHD domain ATP-synt_B PF00430.13 EON97511.1 - 1 9.1 26.5 1.8 8.3 18.4 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Borrelia_P83 PF05262.6 EON97511.1 - 7.7 4.6 22.1 10 4.2 15.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TRAP-gamma PF07074.7 EON97511.1 - 9.8 5.6 9.7 16 4.9 6.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) BTB PF00651.26 EON97512.1 - 3.4e-06 26.9 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_11 PF14833.1 EON97513.1 - 3.1e-37 127.3 0.1 2.3e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EON97513.1 - 2.3e-35 121.8 0.3 3.7e-35 121.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EON97513.1 - 0.00016 22.0 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EON97513.1 - 0.00086 19.0 0.2 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EON97513.1 - 0.012 15.0 0.1 0.051 13.0 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EON97513.1 - 0.081 12.2 0.1 2.2 7.6 0.1 2.6 1 1 2 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mago_nashi PF02792.9 EON97514.1 - 1e-75 252.2 0.5 1.2e-75 251.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein HSP70 PF00012.15 EON97515.1 - 3.9e-266 883.7 15.6 4.4e-266 883.5 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EON97515.1 - 9.8e-15 53.9 4.7 6.2e-13 48.0 0.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EON97515.1 - 1.2e-05 25.0 0.2 0.00027 20.6 0.0 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 EON97515.1 - 0.048 13.3 3.7 0.098 12.3 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) FtsA PF14450.1 EON97515.1 - 0.079 12.8 10.8 6.7 6.5 1.1 4.8 2 1 1 3 3 3 0 Cell division protein FtsA DnaG_DnaB_bind PF08278.6 EON97515.1 - 0.54 10.4 3.1 1.6 8.9 2.1 1.8 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Melibiase PF02065.13 EON97516.1 - 0.013 14.2 0.1 0.024 13.3 0.0 1.4 2 0 0 2 2 2 0 Melibiase Glyco_hydro_15 PF00723.16 EON97517.1 - 7e-81 272.0 0.1 9.1e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EON97517.1 - 8.6e-23 79.7 0.8 2.2e-22 78.4 0.6 1.7 1 0 0 1 1 1 1 Starch binding domain Amino_oxidase PF01593.19 EON97518.1 - 0.00071 18.7 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EON97518.1 - 0.002 18.2 0.3 0.048 13.7 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97518.1 - 0.0054 16.7 1.6 0.022 14.7 1.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON97518.1 - 0.015 15.1 0.2 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCHH PF10283.4 EON97518.1 - 0.021 14.6 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif FAD_binding_3 PF01494.14 EON97518.1 - 0.028 13.4 0.3 0.12 11.4 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.19 EON97518.1 - 0.035 13.0 0.1 0.43 9.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON97518.1 - 0.088 11.7 1.0 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EON97518.1 - 0.19 11.5 0.4 9.6 5.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EON97518.1 - 0.21 10.0 0.8 3.6 5.9 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 EON97519.1 - 2.9e-37 128.1 30.1 2.9e-37 128.1 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TAF8_C PF10406.4 EON97519.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Epimerase PF01370.16 EON97520.1 - 7.7e-16 58.2 0.0 1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON97520.1 - 2e-12 47.4 0.9 2.4e-12 47.2 0.4 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EON97520.1 - 2.3e-08 33.0 0.3 3.4e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EON97520.1 - 2.2e-07 30.0 0.2 4.3e-07 29.1 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EON97520.1 - 6.6e-07 28.8 0.2 1.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EON97520.1 - 7.1e-05 22.7 0.1 0.00019 21.4 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EON97520.1 - 0.00053 18.9 1.5 0.0011 17.9 0.4 2.0 2 1 1 3 3 3 1 Male sterility protein Saccharop_dh PF03435.13 EON97520.1 - 0.00055 19.0 0.4 0.00082 18.4 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EON97520.1 - 0.0046 16.9 1.8 0.0046 16.9 1.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 EON97520.1 - 0.083 12.8 0.3 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EON97520.1 - 0.15 10.9 0.4 4.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Lipase_3 PF01764.20 EON97521.1 - 6.1e-35 119.8 0.0 9.6e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EON97521.1 - 0.0028 17.3 1.9 0.014 15.1 1.3 2.1 1 1 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.7 EON97521.1 - 0.0061 16.0 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Lipase3_N PF03893.11 EON97521.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Abhydrolase_6 PF12697.2 EON97521.1 - 0.015 15.2 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97521.1 - 0.035 13.8 1.0 0.098 12.4 0.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EON97521.1 - 0.26 10.6 0.9 1.7 7.9 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) GTP_EFTU PF00009.22 EON97522.1 - 1.1e-61 207.5 0.2 1.7e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EON97522.1 - 1.9e-37 127.4 0.0 4.6e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EON97522.1 - 9.3e-22 76.7 0.0 1.4e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EON97522.1 - 4.2e-12 46.0 1.1 1.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EON97522.1 - 1.2e-11 44.2 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EON97522.1 - 0.00011 22.0 0.2 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-met PF12874.2 EON97523.1 - 7.8e-06 25.9 1.0 1.5e-05 25.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EON97523.1 - 0.00045 19.8 0.1 0.00067 19.2 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EON97523.1 - 0.06 12.6 0.9 0.098 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Adaptin_N PF01602.15 EON97524.1 - 3.2e-94 316.1 6.6 5.2e-94 315.4 4.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EON97524.1 - 4.1e-63 210.9 0.0 1.1e-62 209.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EON97524.1 - 1.5e-62 209.4 0.4 3e-62 208.4 0.3 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EON97524.1 - 6.3e-11 42.4 7.8 3.5e-07 30.3 0.0 4.5 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EON97524.1 - 0.00011 22.0 6.7 0.0042 16.9 0.1 3.6 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EON97524.1 - 0.0022 17.9 2.3 0.45 10.7 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.1 EON97524.1 - 0.013 15.6 0.1 0.051 13.7 0.1 2.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.1 EON97524.1 - 0.014 15.8 3.2 2.4 8.7 0.0 4.5 4 1 1 5 5 5 0 HEAT-like repeat DUF1542 PF07564.6 EON97524.1 - 0.017 15.1 0.9 0.064 13.2 0.6 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) RE_Alw26IDE PF09665.5 EON97524.1 - 4.3 5.9 6.2 4.3 5.9 0.1 3.0 3 1 1 4 4 4 0 Type II restriction endonuclease (RE_Alw26IDE) DAGK_cat PF00781.19 EON97525.1 - 2.1e-26 91.8 0.0 3.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PRKCSH-like PF12999.2 EON97525.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Glyco_hydro_71 PF03659.9 EON97526.1 - 1.2e-112 376.1 14.1 5.5e-97 324.6 6.5 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Glyco_hydro_3_C PF01915.17 EON97527.1 - 4.4e-54 183.3 0.9 6.4e-53 179.5 0.2 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EON97527.1 - 7.6e-36 123.6 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EON97527.1 - 3.8e-23 81.1 0.1 7.6e-23 80.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EON97527.1 - 0.024 14.7 0.5 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 CARDB 3HCDH_N PF02737.13 EON97528.1 - 4e-53 179.7 0.1 5.1e-53 179.3 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EON97528.1 - 2.3e-33 114.4 0.0 4.5e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EON97528.1 - 0.0015 18.3 0.2 0.0029 17.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EON97528.1 - 0.0046 16.7 0.4 0.0094 15.6 0.2 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EON97528.1 - 0.013 14.4 0.1 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DAO PF01266.19 EON97528.1 - 0.018 13.9 0.8 0.039 12.8 0.4 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EON97528.1 - 0.027 14.4 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 EON97528.1 - 0.05 13.0 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EON97528.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON97528.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EON97528.1 - 0.11 12.9 2.6 0.16 12.4 0.8 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EON97528.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1996 PF09362.5 EON97529.1 - 6.7e-13 48.8 1.2 9.8e-13 48.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BCS1_N PF08740.6 EON97530.1 - 2.3e-23 82.7 0.6 4.5e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EON97530.1 - 5.1e-17 62.3 0.0 1.3e-07 31.8 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EON97530.1 - 6.7e-05 23.6 0.2 0.00085 20.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EON97530.1 - 0.00071 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EON97530.1 - 0.003 16.9 0.0 0.0079 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EON97530.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EON97530.1 - 0.022 14.4 0.0 0.091 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EON97530.1 - 0.028 14.1 0.3 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EON97530.1 - 0.045 13.6 0.5 0.12 12.2 0.2 2.2 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EON97530.1 - 0.051 12.6 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 EON97530.1 - 0.14 11.5 0.4 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 EON97530.1 - 0.19 11.7 2.2 0.45 10.4 0.1 2.5 2 1 1 3 3 3 0 AAA ATPase domain DUF1191 PF06697.7 EON97531.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 EON97531.1 - 1.6 8.3 4.1 0.72 9.4 0.1 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Nefa_Nip30_N PF10187.4 EON97533.1 - 8.8e-23 80.4 8.7 8.8e-23 80.4 6.0 2.6 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 VIT1 PF01988.14 EON97533.1 - 0.9 8.9 2.7 1.4 8.3 1.9 1.4 1 0 0 1 1 1 0 VIT family Opacity PF02462.10 EON97534.1 - 0.047 13.5 0.5 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Opacity family porin protein Zw10 PF06248.8 EON97535.1 - 1.6e-15 56.3 10.4 6.7e-12 44.3 5.6 3.0 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EON97535.1 - 1.9e-05 23.9 1.1 8.6e-05 21.8 0.8 2.0 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal MutS_III PF05192.13 EON97535.1 - 0.0015 18.3 0.1 0.01 15.6 0.1 2.4 1 1 0 1 1 1 1 MutS domain III Ku_C PF03730.9 EON97535.1 - 0.078 13.5 0.1 0.72 10.4 0.0 2.6 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm ThiF PF00899.16 EON97536.1 - 4e-52 175.6 0.4 1.4e-31 109.1 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EON97536.1 - 1.4e-40 138.3 0.0 1.8e-39 134.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EON97536.1 - 4.2e-37 125.5 5.1 1.8e-27 94.7 0.2 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EON97536.1 - 5.4e-24 83.3 1.7 1.6e-21 75.4 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site SH3_1 PF00018.23 EON97537.1 - 2.3e-09 36.4 0.2 7.1e-09 34.9 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON97537.1 - 5.4e-08 32.2 0.2 1.4e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EON97537.1 - 1.9e-07 30.4 0.0 4.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EON97538.1 - 2.9e-08 32.8 3.5 3e-08 32.7 2.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glucos_trans_II PF14264.1 EON97538.1 - 0.00019 20.5 1.5 0.056 12.4 0.1 2.0 2 0 0 2 2 2 2 Glucosyl transferase GtrII Sugar_tr PF00083.19 EON97538.1 - 0.061 11.9 3.9 0.11 11.1 2.7 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter DUF308 PF03729.8 EON97538.1 - 2 8.4 9.0 7 6.7 0.5 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) ATP-synt_F PF01990.12 EON97539.1 - 0.044 14.1 0.5 0.074 13.4 0.3 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Mre11_DNA_bind PF04152.9 EON97539.1 - 0.065 13.0 2.7 0.1 12.4 1.9 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain adh_short PF00106.20 EON97540.1 - 4e-19 69.1 1.4 5.3e-19 68.7 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97540.1 - 1.8e-13 50.8 0.0 2.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 EON97540.1 - 4.1e-06 26.3 0.2 7.9e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 EON97540.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EON97540.1 - 0.00044 20.2 0.1 0.00076 19.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EON97540.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 EON97540.1 - 0.042 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EON97540.1 - 0.074 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EON97540.1 - 0.11 11.8 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EON97540.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PGP_phosphatase PF09419.5 EON97541.1 - 2.1e-64 215.9 0.0 2.4e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EON97541.1 - 0.00033 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like eIF3g PF12353.3 EON97542.1 - 7.2e-47 158.4 2.8 1.2e-46 157.7 1.9 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EON97542.1 - 2e-15 56.1 0.0 3.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON97542.1 - 1.4e-13 50.5 0.1 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97542.1 - 1.9e-07 30.8 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 EON97543.1 - 1.4e-10 41.1 0.0 2.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON97543.1 - 1.5e-07 32.0 0.0 2.5e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON97543.1 - 2.8e-07 30.2 0.0 8.5e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON97543.1 - 0.00022 21.6 0.0 0.0013 19.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON97543.1 - 0.00034 21.0 0.0 0.00068 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON97543.1 - 0.025 13.7 0.0 0.27 10.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EON97543.1 - 0.057 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EON97543.1 - 0.091 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EON97543.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EON97544.1 - 3.2e-09 36.6 0.1 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EON97544.1 - 1.8e-07 31.1 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 EON97545.1 - 9.1e-70 235.4 20.8 1e-69 235.2 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97545.1 - 1.5e-11 43.6 17.5 1.5e-11 43.6 12.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CAAD PF14159.1 EON97545.1 - 7.6 6.2 8.9 5.1 6.8 3.0 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PEPcase_2 PF14010.1 EON97546.1 - 0.14 10.3 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Orn_Arg_deC_N PF02784.11 EON97547.1 - 2.6e-78 262.7 0.0 3.5e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EON97547.1 - 5e-31 106.8 0.1 1.2e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MFS_1 PF07690.11 EON97548.1 - 2.5e-30 105.3 30.2 2.5e-30 105.3 20.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Nop16 PF09420.5 EON97549.1 - 6.4e-52 175.9 0.7 7.7e-52 175.7 0.5 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 p450 PF00067.17 EON97550.1 - 4.9e-36 124.2 0.0 6.2e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M16_C PF05193.16 EON97551.1 - 1.6e-19 70.3 0.0 2.6e-15 56.5 0.0 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EON97551.1 - 3.1e-06 27.0 0.0 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Nucleoplasmin PF03066.10 EON97551.1 - 0.0041 16.6 8.9 0.0041 16.6 6.1 1.9 2 0 0 2 2 2 1 Nucleoplasmin Sporozoite_P67 PF05642.6 EON97551.1 - 0.048 11.5 4.2 0.071 10.9 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen M16C_assoc PF08367.6 EON97551.1 - 0.051 12.4 1.6 0.67 8.7 0.7 2.3 2 0 0 2 2 2 0 Peptidase M16C associated NOA36 PF06524.7 EON97551.1 - 3.1 6.9 13.4 4.7 6.3 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein Dak1 PF02733.12 EON97552.1 - 1.9e-104 348.7 0.1 2.6e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EON97552.1 - 4.8e-42 143.5 2.2 4.8e-42 143.5 1.5 2.0 2 0 0 2 2 2 1 DAK2 domain Peptidase_S24 PF00717.18 EON97553.1 - 1.2e-07 31.2 0.5 1.9e-07 30.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EON97553.1 - 1.2e-06 28.0 0.0 0.00012 21.6 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Anemone_cytotox PF06369.7 EON97554.1 - 0.052 12.9 0.2 0.083 12.2 0.1 1.3 1 1 0 1 1 1 0 Sea anemone cytotoxic protein GST_N_3 PF13417.1 EON97554.1 - 0.073 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Folate_carrier PF01770.13 EON97554.1 - 0.082 11.4 0.1 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2964 PF11177.3 EON97554.1 - 0.11 12.4 0.7 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) NVEALA PF14055.1 EON97554.1 - 0.2 11.3 0.9 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 NVEALA protein Anoctamin PF04547.7 EON97555.1 - 2.4e-123 412.1 9.3 3.1e-123 411.8 6.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel MARVEL PF01284.18 EON97556.1 - 2.2e-10 40.4 5.7 3.1e-10 40.0 3.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 EON97556.1 - 0.00028 20.9 1.3 0.00046 20.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) YtpI PF14007.1 EON97556.1 - 0.011 15.6 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 YtpI-like protein Voltage_CLC PF00654.15 EON97557.1 - 1.6e-88 297.1 27.8 1.6e-88 297.1 19.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EON97557.1 - 7.4e-12 44.8 0.1 9.9e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain Rox3 PF08633.5 EON97558.1 - 5.9e-50 170.2 0.1 8.5e-50 169.7 0.1 1.2 1 0 0 1 1 1 1 Rox3 mediator complex subunit Aldedh PF00171.17 EON97559.1 - 4.2e-133 444.0 0.0 5.2e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EON97559.1 - 4.1e-06 25.7 0.0 1e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EON97559.1 - 0.086 12.0 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GMC_oxred_C PF05199.8 EON97560.1 - 1.7e-31 109.4 0.0 2.6e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EON97560.1 - 1.2e-26 93.5 0.0 3.8e-18 65.6 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EON97560.1 - 2.2e-05 24.4 0.1 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON97560.1 - 4.3e-05 23.4 0.3 0.0062 16.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON97560.1 - 0.0042 15.9 0.0 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EON97560.1 - 0.0047 15.8 0.2 0.06 12.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON97560.1 - 0.024 13.0 0.0 0.046 12.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EON97560.1 - 0.031 13.3 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EON97560.1 - 0.047 12.6 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EON97560.1 - 0.12 11.8 0.1 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EON97560.1 - 0.18 11.4 0.0 0.48 10.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RVT_1 PF00078.22 EON97561.1 - 2.5e-07 30.2 0.0 1.1e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Vac_ImportDeg PF09783.4 EON97562.1 - 2e-60 203.3 0.9 2.4e-60 203.0 0.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Dala_Dala_lig_C PF07478.8 EON97562.1 - 0.064 12.6 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus MFS_1 PF07690.11 EON97563.1 - 0.028 13.1 0.1 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Serglycin PF04360.7 EON97564.1 - 0.052 13.2 0.2 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Serglycin SR-25 PF10500.4 EON97564.1 - 0.11 11.9 7.0 0.2 11.0 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.18 EON97565.1 - 1.4e-63 214.4 0.2 2.3e-63 213.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON97565.1 - 1.6e-05 24.7 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EON97565.1 - 8.1e-05 22.2 15.5 8.1e-05 22.2 10.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EON97565.1 - 0.00012 20.9 0.0 0.0004 19.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.1 EON97565.1 - 0.00044 20.0 14.9 0.00044 20.0 10.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EON97565.1 - 0.0028 17.6 14.2 0.0028 17.6 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AT_hook PF02178.14 EON97565.1 - 0.019 14.6 15.2 0.24 11.2 3.2 3.2 2 0 0 2 2 2 0 AT hook motif Amidohydro_2 PF04909.9 EON97566.1 - 8.3e-45 153.4 0.1 1e-44 153.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase GHMP_kinases_N PF00288.21 EON97567.1 - 7.9e-16 57.8 1.1 1.8e-15 56.7 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EON97567.1 - 9.2e-10 38.5 0.1 3.4e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal NAP PF00956.13 EON97568.1 - 4.9e-49 166.6 1.2 7.3e-49 166.0 0.8 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.7 EON97568.1 - 0.0059 16.3 1.8 0.0059 16.3 1.2 2.3 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 EON97568.1 - 0.044 13.3 12.1 0.05 13.1 1.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin Cir_N PF10197.4 EON97568.1 - 0.053 13.5 0.2 0.053 13.5 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Bd3614_N PF14442.1 EON97568.1 - 1.8 8.5 4.7 3.5 7.5 3.2 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF4611 PF15387.1 EON97568.1 - 5.7 7.1 15.2 16 5.6 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAT PF02259.18 EON97569.1 - 3.4e-75 253.2 9.2 6.2e-75 252.3 6.4 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EON97569.1 - 1.2e-24 87.1 0.4 4.4e-24 85.2 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.23 EON97569.1 - 5.1e-19 67.9 0.0 9.7e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme HEAT PF02985.17 EON97569.1 - 0.0034 17.3 2.9 0.49 10.6 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat TPR_8 PF13181.1 EON97569.1 - 0.017 14.8 4.8 0.42 10.5 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EON97569.1 - 0.037 13.9 2.5 3.3 7.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AMP-binding_C PF13193.1 EON97569.1 - 0.085 13.8 0.0 1.1 10.3 0.0 2.9 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain TPR_11 PF13414.1 EON97569.1 - 0.36 10.5 8.8 18 5.0 0.1 4.0 3 0 0 3 3 3 0 TPR repeat SICA_beta PF12878.2 EON97569.1 - 0.76 9.5 0.0 2.2 8.0 0.0 1.8 1 0 0 1 1 1 0 SICA extracellular beta domain TPR_2 PF07719.12 EON97569.1 - 3.5 7.7 12.0 4.7 7.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Aa_trans PF01490.13 EON97570.1 - 2.2e-85 286.5 33.4 2.7e-85 286.3 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 EON97570.1 - 1.7e-20 72.2 0.0 2.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EON97570.1 - 1e-06 27.7 0.0 6.2e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MitoNEET_N PF10660.4 EON97570.1 - 0.78 9.6 3.7 9 6.2 0.2 3.3 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus TFIIB PF00382.14 EON97571.1 - 3e-35 119.8 0.7 3.4e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EON97571.1 - 4.6e-10 38.6 1.2 7.7e-10 37.9 0.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EON97571.1 - 0.0069 16.2 0.1 1 9.3 0.1 2.4 1 1 0 2 2 2 1 Cyclin, C-terminal domain HTH_5 PF01022.15 EON97571.1 - 0.022 14.4 0.0 0.85 9.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.1 EON97571.1 - 0.037 13.1 0.1 0.8 8.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 EON97571.1 - 0.047 13.0 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Cyclin_N PF00134.18 EON97571.1 - 0.048 13.2 0.2 1.4 8.4 0.0 2.4 2 1 0 2 2 2 0 Cyclin, N-terminal domain GerE PF00196.14 EON97571.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Rrf2 PF02082.15 EON97571.1 - 0.089 12.9 0.0 12 6.1 0.0 2.7 2 1 1 3 3 3 0 Transcriptional regulator Sigma70_r4_2 PF08281.7 EON97571.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 EON97571.1 - 0.12 12.1 0.0 25 4.6 0.0 2.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EON97571.1 - 0.14 11.5 0.1 18 4.8 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PALP PF00291.20 EON97572.1 - 4.2e-44 151.0 1.6 4.7e-44 150.8 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2620 PF10941.3 EON97572.1 - 5 7.1 6.4 1.3 9.0 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF2620 Pantoate_ligase PF02569.10 EON97573.1 - 1.2e-78 263.7 0.0 1.8e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase MGAT2 PF05060.9 EON97573.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) STAS PF01740.16 EON97574.1 - 4.5e-08 32.5 0.0 6.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EON97574.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain LSM PF01423.17 EON97575.1 - 5.4e-18 64.3 0.1 7.1e-18 63.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Inhibitor_I9 PF05922.11 EON97576.1 - 1.2e-14 54.6 0.1 1.3e-14 54.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 AIG2 PF06094.7 EON97577.1 - 3.7e-16 59.4 0.0 4.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family cobW PF02492.14 EON97579.1 - 1.7e-39 135.0 0.0 2.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EON97579.1 - 0.0031 17.0 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EON97579.1 - 0.0053 16.4 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EON97579.1 - 0.0073 16.3 0.1 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EON97579.1 - 0.021 14.7 0.1 0.074 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EON97579.1 - 0.022 13.7 0.1 0.08 11.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EON97579.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EON97579.1 - 0.023 14.4 0.1 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EON97579.1 - 0.036 13.5 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EON97579.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EON97579.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Alg14 PF08660.6 EON97579.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like SRP54 PF00448.17 EON97579.1 - 0.099 12.0 0.1 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CRC_subunit PF08624.5 EON97580.1 - 1.5e-56 190.1 0.0 2.4e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit FoP_duplication PF13865.1 EON97580.1 - 0.77 10.2 5.4 0.35 11.3 1.2 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Nop14 PF04147.7 EON97580.1 - 1.7 6.4 6.3 2.5 5.9 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Troponin-I_N PF11636.3 EON97580.1 - 5.9 6.6 12.0 2.4 7.9 5.6 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 NMO PF03060.10 EON97581.1 - 5.5e-68 229.5 0.6 6.5e-68 229.3 0.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EON97581.1 - 5e-06 25.6 0.0 0.085 11.7 0.1 2.6 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EON97581.1 - 0.00033 19.6 2.0 0.00069 18.5 1.3 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase TPR_1 PF00515.23 EON97583.1 - 4.1e-30 102.1 5.6 4.8e-05 22.7 0.4 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 EON97583.1 - 3.8e-29 100.6 14.1 8.3e-21 73.9 0.2 5.5 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EON97583.1 - 5.3e-29 99.6 21.1 2.5e-07 30.2 0.0 7.5 6 1 1 7 7 7 7 TPR repeat TPR_2 PF07719.12 EON97583.1 - 7.4e-29 97.3 15.5 0.00032 20.4 0.1 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 EON97583.1 - 4.2e-21 75.0 9.9 0.00019 21.6 0.0 7.6 5 2 1 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EON97583.1 - 5.4e-21 74.3 17.4 3e-07 30.2 0.1 8.6 5 3 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EON97583.1 - 6.1e-21 73.0 14.6 0.0061 17.0 0.0 9.9 5 3 6 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EON97583.1 - 2.3e-16 58.2 1.1 0.0099 15.5 0.1 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EON97583.1 - 9.3e-16 58.0 18.7 7.7e-05 23.2 0.2 7.7 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 EON97583.1 - 4.6e-13 47.8 14.4 0.15 11.9 0.0 9.1 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.1 EON97583.1 - 2.6e-10 39.8 9.8 0.15 12.0 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EON97583.1 - 1.4e-08 34.6 14.4 1.4 9.5 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EON97583.1 - 1e-07 31.6 13.0 0.0082 15.9 0.2 6.7 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EON97583.1 - 1.2e-07 31.3 4.5 8.7 6.8 0.0 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_15 PF13429.1 EON97583.1 - 3.3e-06 26.3 5.6 0.06 12.3 0.2 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 EON97583.1 - 0.0013 18.1 2.4 2.9 7.2 0.0 4.3 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_5 PF12688.2 EON97583.1 - 0.072 13.1 0.3 0.47 10.4 0.0 2.5 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_4 PF07721.9 EON97583.1 - 0.18 12.3 6.2 5.9 7.6 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EON97583.1 - 0.21 11.4 3.9 7.4 6.4 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EON97583.1 - 1.3 8.9 7.9 8.7 6.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PLDc PF00614.17 EON97584.1 - 1.6e-14 53.1 1.1 2.4e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EON97584.1 - 2e-11 43.7 0.1 6.2e-05 22.7 0.0 4.1 4 0 0 4 4 4 3 PLD-like domain WD40 PF00400.27 EON97585.1 - 2.1e-30 103.4 15.8 1.1e-07 31.4 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EON97585.1 - 1.4e-20 73.0 0.2 2.5e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EON97585.1 - 0.00021 19.5 5.5 0.12 10.5 1.5 3.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 CDC45 PF02724.9 EON97586.1 - 1.2e-62 211.9 0.0 1.4e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.4 EON97586.1 - 0.036 12.9 0.3 0.04 12.7 0.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.7 EON97586.1 - 0.069 12.4 5.4 0.081 12.1 3.7 1.1 1 0 0 1 1 1 0 SDA1 DUF336 PF03928.9 EON97587.1 - 3.1e-16 59.3 0.0 3.7e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) ketoacyl-synt PF00109.21 EON97588.1 - 2.4e-20 73.1 0.1 4.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EON97588.1 - 1.1e-19 71.1 0.0 2.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EON97588.1 - 1.9e-18 66.3 0.0 5e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EON97588.1 - 1.4e-10 41.0 0.0 3.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EON97588.1 - 2.1e-05 24.5 0.0 0.0001 22.2 0.0 2.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97588.1 - 0.0061 16.2 0.0 0.03 13.9 0.0 2.2 1 0 0 1 1 1 1 KR domain IncA PF04156.9 EON97588.1 - 3.3 7.2 6.1 0.22 11.1 0.3 1.8 2 0 0 2 2 2 0 IncA protein CUE PF02845.11 EON97589.1 - 2.8e-08 33.0 0.0 4.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain WSC PF01822.14 EON97590.1 - 2.5e-13 49.7 7.7 2.5e-13 49.7 5.3 3.0 3 0 0 3 3 3 1 WSC domain Glyco_hydro_16 PF00722.16 EON97590.1 - 7.1e-07 28.6 0.3 4.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Esterase_phd PF10503.4 EON97591.1 - 0.00072 18.8 0.2 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EON97591.1 - 0.0047 16.6 0.1 0.0077 16.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LSM PF01423.17 EON97592.1 - 7.9e-21 73.3 0.1 8.8e-21 73.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain AAA PF00004.24 EON97593.1 - 2.1e-11 44.1 0.0 4.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EON97593.1 - 1.8e-06 28.1 0.0 6.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EON97593.1 - 5.9e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EON97593.1 - 4.8e-05 23.0 0.1 0.00037 20.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EON97593.1 - 5.5e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EON97593.1 - 0.00053 19.8 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EON97593.1 - 0.0007 19.4 0.5 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EON97593.1 - 0.00093 17.9 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EON97593.1 - 0.0011 19.8 0.0 0.0041 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON97593.1 - 0.002 18.1 0.1 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EON97593.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EON97593.1 - 0.017 14.7 0.0 0.073 12.7 0.0 2.2 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EON97593.1 - 0.043 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EON97593.1 - 0.072 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EON97593.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 EON97593.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MT0933_antitox PF14013.1 EON97594.1 - 0.61 10.2 4.2 7 6.8 2.8 2.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein Methyltransf_3 PF01596.12 EON97595.1 - 6e-13 48.3 0.1 1.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EON97595.1 - 1.2e-11 45.3 0.0 3.5e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Glycos_transf_3 PF00591.16 EON97596.1 - 6e-61 206.0 0.0 9.5e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EON97596.1 - 1.9e-09 36.9 0.0 3.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain TPR_11 PF13414.1 EON97597.1 - 8.8e-20 70.1 13.1 4.9e-17 61.3 5.0 2.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EON97597.1 - 4.3e-16 57.4 10.0 7e-07 28.6 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EON97597.1 - 5.3e-16 57.4 12.6 4.5e-08 32.3 0.7 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EON97597.1 - 1.1e-10 41.8 20.2 3e-09 37.3 5.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EON97597.1 - 1.9e-08 33.8 6.6 0.00078 19.4 0.5 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON97597.1 - 5.4e-08 32.6 7.4 0.0012 18.6 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EON97597.1 - 6e-07 29.5 12.3 0.0048 17.4 1.6 3.8 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EON97597.1 - 6.8e-06 26.3 8.5 4.1e-05 23.8 3.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EON97597.1 - 1.4e-05 24.4 1.2 0.018 14.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EON97597.1 - 5.6e-05 23.4 0.8 0.083 13.1 0.0 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_8 PF13181.1 EON97597.1 - 0.00014 21.4 9.0 0.042 13.6 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EON97597.1 - 0.0016 18.3 6.5 0.23 11.4 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EON97597.1 - 0.0019 18.0 0.6 0.0052 16.6 0.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat XPC-binding PF09280.6 EON97597.1 - 0.026 13.9 2.1 0.026 13.9 1.4 2.0 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.1 EON97597.1 - 0.03 14.7 10.0 0.21 12.1 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CTDII PF01556.13 EON97598.1 - 2.7e-28 97.6 1.5 4.7e-22 77.6 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EON97598.1 - 2.8e-25 87.8 2.4 4.1e-25 87.2 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EON97598.1 - 3.5e-11 42.9 20.6 6.7e-11 42.0 14.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EON97598.1 - 0.52 10.0 9.2 2.5 7.8 0.8 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cyclin PF08613.6 EON97599.1 - 1.2e-12 48.4 0.0 2.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Rep_fac-A_3 PF08661.6 EON97600.1 - 1.6e-20 73.0 0.0 1.8e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 IF3_C PF00707.17 EON97601.1 - 1.5e-14 53.5 1.0 2.3e-14 52.8 0.7 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EON97601.1 - 1.6e-06 27.5 1.4 8.3e-06 25.2 0.6 2.0 1 1 1 2 2 2 1 Mitochondrial translation initiation factor DUF3563 PF12086.3 EON97601.1 - 0.027 14.1 0.4 0.1 12.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3563) Peptidase_M48 PF01435.13 EON97602.1 - 4.1e-48 163.8 0.0 6.6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EON97602.1 - 0.0073 15.3 0.1 0.017 14.1 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 EON97602.1 - 0.058 12.5 1.1 0.098 11.8 0.2 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF955 PF06114.8 EON97602.1 - 0.075 12.7 0.2 0.98 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF1772 PF08592.6 EON97602.1 - 0.28 10.8 1.5 0.34 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) PPTA PF01239.17 EON97603.1 - 5.9e-40 132.9 7.5 9e-08 31.1 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.1 EON97603.1 - 0.0039 16.8 1.8 0.8 9.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TauD PF02668.11 EON97604.1 - 1.4e-52 178.9 0.1 1.7e-52 178.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2051 PF09738.4 EON97604.1 - 0.14 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) TauD PF02668.11 EON97605.1 - 6.2e-57 193.2 0.4 7.6e-57 192.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4291 PF14124.1 EON97607.1 - 1.9e-64 216.6 0.3 2.3e-64 216.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Ribosomal_L4 PF00573.17 EON97607.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family tRNA-synt_1g PF09334.6 EON97608.1 - 1.3e-122 409.3 0.1 3.8e-122 407.7 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EON97608.1 - 7.2e-26 90.3 6.9 7.2e-10 37.5 0.2 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EON97608.1 - 6.6e-10 38.5 0.0 0.00016 20.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EON97608.1 - 0.00038 20.2 0.0 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Peptidase_C28 PF05408.6 EON97608.1 - 0.065 12.6 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Acyltransferase PF01553.16 EON97609.1 - 1.2e-15 57.1 0.0 2.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sugar_tr PF00083.19 EON97610.1 - 1.6e-112 376.3 22.2 1.9e-112 376.1 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97610.1 - 1.1e-24 86.8 23.6 1.1e-24 86.8 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 EON97610.1 - 0.0024 16.6 0.9 0.0024 16.6 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) WBS28 PF15164.1 EON97610.1 - 0.0053 15.8 0.1 0.0086 15.1 0.1 1.2 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue SR-25 PF10500.4 EON97611.1 - 0.5 9.7 5.8 0.48 9.8 4.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyt-b5 PF00173.23 EON97612.1 - 2.2e-12 46.6 0.0 3.7e-12 45.8 0.0 1.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RPAP2_Rtr1 PF04181.8 EON97613.1 - 2.6e-19 69.0 0.1 5e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Pro_CA PF00484.14 EON97614.1 - 3.6e-49 166.6 0.1 5.5e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase AAA_17 PF13207.1 EON97615.1 - 9.4e-07 29.6 0.0 2.6e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON97615.1 - 1.2e-06 28.6 0.1 1.4e-06 28.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EON97615.1 - 1.3e-06 27.7 0.0 3.3e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EON97615.1 - 1.7e-05 25.0 0.1 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EON97615.1 - 2e-05 24.2 0.5 4.7e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 Part of AAA domain PRK PF00485.13 EON97615.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EON97615.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EON97615.1 - 0.00017 20.5 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EON97615.1 - 0.00029 20.9 0.0 0.00068 19.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EON97615.1 - 0.00045 20.0 0.2 0.002 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EON97615.1 - 0.0021 17.7 0.1 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EON97615.1 - 0.003 17.2 0.0 0.0086 15.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 EON97615.1 - 0.0033 17.0 0.0 0.047 13.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EON97615.1 - 0.0044 16.4 0.1 0.0092 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EON97615.1 - 0.0064 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EON97615.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.6 2 0 0 2 2 1 0 NTPase T2SE PF00437.15 EON97615.1 - 0.014 14.3 0.0 0.027 13.3 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EON97615.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EON97615.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EON97615.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EON97615.1 - 0.022 14.6 0.3 0.046 13.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain CPT PF07931.7 EON97615.1 - 0.023 14.3 0.1 0.23 11.0 0.1 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 EON97615.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EON97615.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EON97615.1 - 0.032 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EON97615.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EON97615.1 - 0.048 13.1 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Torsin PF06309.6 EON97615.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Torsin ArgK PF03308.11 EON97615.1 - 0.057 12.1 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 EON97615.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EON97615.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EON97615.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EON97615.1 - 0.081 11.9 0.1 0.16 10.9 0.0 1.5 2 0 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EON97615.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EON97615.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ADK PF00406.17 EON97615.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase TIP49 PF06068.8 EON97615.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus zf-BED PF02892.10 EON97616.1 - 0.002 17.8 0.2 0.002 17.8 0.1 2.3 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 EON97616.1 - 0.017 15.0 5.9 0.039 13.8 4.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 EON97616.1 - 0.04 13.8 4.4 0.11 12.4 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GST_N_2 PF13409.1 EON97617.1 - 2.9e-21 75.2 0.1 1e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EON97617.1 - 1.3e-14 53.7 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EON97617.1 - 3.3e-06 26.9 0.0 1e-05 25.4 0.0 1.7 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EON97617.1 - 8.1e-06 26.2 0.0 2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EON97617.1 - 2.5e-05 24.4 0.1 0.0014 18.8 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aldo_ket_red PF00248.16 EON97618.1 - 1.6e-44 151.8 0.0 2.2e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family XH PF03469.9 EON97618.1 - 0.039 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 XH domain HAD_2 PF13419.1 EON97618.1 - 0.12 12.6 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4398 PF14346.1 EON97619.1 - 0.0066 16.4 0.3 0.0095 15.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) GHMP_kinases_N PF00288.21 EON97620.1 - 3.5e-18 65.4 0.0 7.6e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EON97620.1 - 2.5e-09 37.2 0.0 5.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EON97620.1 - 0.022 14.0 0.0 0.052 12.8 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Arylsulfotran_2 PF14269.1 EON97621.1 - 8e-35 120.4 0.1 1.1e-22 80.5 0.3 2.2 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EON97621.1 - 1.1e-07 30.7 0.1 1.7e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Protocadherin PF08374.6 EON97622.1 - 0.0029 17.2 1.0 0.0077 15.8 0.0 2.0 2 0 0 2 2 2 1 Protocadherin Rifin_STEVOR PF02009.11 EON97622.1 - 0.0048 16.5 2.0 0.012 15.2 1.4 1.4 1 1 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 EON97622.1 - 0.0059 16.6 1.6 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 EON97622.1 - 0.0076 14.5 0.3 0.038 12.2 0.1 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EON97622.1 - 0.02 14.1 0.1 0.02 14.1 0.1 2.3 3 0 0 3 3 2 0 Transmembrane alpha-helix domain DUF1469 PF07332.6 EON97622.1 - 0.022 14.4 2.2 2.7 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF4293 PF14126.1 EON97622.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4293) DUF4366 PF14283.1 EON97622.1 - 0.051 13.0 0.4 0.15 11.4 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) IncA PF04156.9 EON97622.1 - 0.06 12.9 0.1 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 IncA protein EphA2_TM PF14575.1 EON97622.1 - 0.069 13.5 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.1 EON97622.1 - 0.12 10.8 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless Otopetrin PF03189.8 EON97622.1 - 0.21 10.5 0.4 0.49 9.3 0.3 1.5 1 1 0 1 1 1 0 Otopetrin Plasmodium_Vir PF05795.6 EON97622.1 - 0.39 9.8 0.6 0.55 9.3 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Myosin_HC-like PF07058.6 EON97622.1 - 0.56 9.2 2.0 0.76 8.8 1.4 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like Podoplanin PF05808.6 EON97622.1 - 6.6 6.2 19.6 6.9e+02 -0.4 14.1 2.8 2 1 0 2 2 2 0 Podoplanin RhoGAP PF00620.22 EON97623.1 - 4e-46 156.3 0.1 4e-46 156.3 0.0 2.6 2 2 0 2 2 2 1 RhoGAP domain SlyX PF04102.7 EON97623.1 - 0.012 15.9 1.8 0.012 15.9 1.3 3.9 4 1 0 4 4 4 0 SlyX IFT20 PF14931.1 EON97623.1 - 2.3 8.1 12.5 0.035 13.9 2.4 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Syntaxin_2 PF14523.1 EON97623.1 - 3.1 7.8 11.9 1.4e+02 2.5 7.6 3.5 2 1 0 2 2 2 0 Syntaxin-like protein CENP-F_leu_zip PF10473.4 EON97623.1 - 5 6.9 20.3 2.5 7.9 5.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tim54 PF11711.3 EON97624.1 - 7.5e-121 403.3 4.8 6.9e-81 271.7 0.0 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Iso_dh PF00180.15 EON97625.1 - 9.1e-98 327.3 0.0 1.1e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RRM_6 PF14259.1 EON97626.1 - 1.5e-08 34.5 0.0 5e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON97626.1 - 3.2e-08 33.1 0.0 3.9e-06 26.4 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97626.1 - 0.00012 21.8 0.0 0.0027 17.4 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 EON97626.1 - 5.1 5.9 9.1 0.12 11.2 0.5 1.9 1 1 0 2 2 2 0 AAR2 protein SnoaL_2 PF12680.2 EON97627.1 - 1.5e-07 31.7 0.1 1.9e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EON97627.1 - 0.00039 20.5 0.2 0.0005 20.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EON97627.1 - 0.0011 19.0 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EON97627.1 - 0.0019 18.1 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4240 PF14024.1 EON97627.1 - 0.013 15.3 0.1 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) UCH PF00443.24 EON97628.1 - 1.4e-36 126.0 0.0 1.9e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EON97628.1 - 2.5e-05 23.8 0.0 0.00017 21.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 EON97628.1 - 0.13 12.2 0.1 9 6.2 0.0 2.8 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Ribosomal_L38e PF01781.13 EON97629.1 - 8.9e-33 111.8 4.5 1.1e-32 111.6 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family WD40 PF00400.27 EON97630.1 - 3.7e-21 74.1 0.6 3.5e-05 23.5 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat MFS_1 PF07690.11 EON97631.1 - 4.7e-27 94.6 26.4 1.3e-26 93.1 17.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EON97631.1 - 1.4 8.8 10.3 0.13 12.1 0.2 3.0 3 0 0 3 3 3 0 MFS_1 like family Fungal_trans_2 PF11951.3 EON97632.1 - 3.1e-36 124.8 0.0 6.9e-36 123.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain YvbH_ext PF11724.3 EON97632.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Glyco_hydro_18 PF00704.23 EON97633.1 - 5.6e-12 45.7 0.7 6.5e-11 42.2 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EON97634.1 - 2.5e-70 236.6 0.0 3.4e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97634.1 - 3.2e-33 114.9 0.0 4.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EON97634.1 - 4.8e-12 46.1 1.5 1.5e-11 44.6 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EON97634.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EON97634.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.13 EON97635.1 - 2e-23 82.6 0.1 3.3e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON97635.1 - 5.4e-09 35.8 11.4 9.5e-09 35.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Taxilin PF09728.4 EON97636.1 - 3.3e-91 305.5 68.1 5.3e-91 304.9 47.2 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 EON97636.1 - 0.0037 16.9 66.9 1.4 8.6 13.4 5.2 2 2 2 4 4 4 4 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EON97636.1 - 2.6 5.8 43.9 0.55 8.0 12.4 2.3 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EON97636.1 - 8.1 6.1 39.7 7.9 6.2 7.2 3.7 2 2 1 3 3 3 0 Laminin Domain II M16C_assoc PF08367.6 EON97638.1 - 1.7e-58 197.4 0.0 2.4e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EON97638.1 - 2.2e-33 115.4 0.0 1.3e-19 70.6 0.0 3.4 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EON97638.1 - 9.7e-08 31.8 0.0 1.2e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DAO PF01266.19 EON97639.1 - 4.4e-58 196.8 6.5 3.1e-57 194.0 4.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON97639.1 - 3.4e-06 27.3 0.2 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97639.1 - 0.00012 22.0 0.2 0.00033 20.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EON97639.1 - 0.00033 19.4 2.1 0.001 17.7 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.14 EON97639.1 - 0.0019 17.4 0.2 0.19 10.8 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Mqo PF06039.10 EON97639.1 - 0.002 16.4 0.0 0.62 8.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 EON97639.1 - 0.0028 17.5 0.7 2.8 7.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EON97639.1 - 0.01 14.8 0.1 0.024 13.6 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EON97639.1 - 0.012 15.7 0.0 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ank PF00023.25 EON97640.1 - 0.05 13.4 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat TctB PF07331.6 EON97641.1 - 0.0068 16.0 0.0 0.12 11.9 0.0 2.6 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Nodulin-like PF06813.8 EON97641.1 - 0.012 14.9 0.4 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Nodulin-like SecG PF03840.9 EON97641.1 - 0.042 13.5 0.7 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit DUF4131 PF13567.1 EON97641.1 - 0.11 11.9 3.2 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Brix PF04427.13 EON97642.1 - 1.8e-57 194.0 0.0 2.8e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Abhydrolase_6 PF12697.2 EON97643.1 - 2.1e-37 129.1 6.7 2.5e-37 128.9 4.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97643.1 - 8.5e-22 77.4 1.6 2.7e-21 75.8 1.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97643.1 - 5.1e-11 42.5 0.6 6.3e-08 32.4 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON97643.1 - 6.8e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EON97643.1 - 0.00033 20.5 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein PAF-AH_p_II PF03403.8 EON97643.1 - 0.00033 19.0 0.0 0.0022 16.3 0.0 1.9 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 EON97643.1 - 0.011 15.2 1.1 0.6 9.6 0.8 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.9 EON97643.1 - 0.015 13.8 0.0 3 6.2 0.0 2.1 2 0 0 2 2 2 0 Ndr family Thioesterase PF00975.15 EON97643.1 - 0.084 13.0 0.0 2.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S15 PF02129.13 EON97643.1 - 0.09 12.1 0.5 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Bac_rhamnosid PF05592.6 EON97644.1 - 2.6e-132 441.6 0.0 3.1e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EON97644.1 - 8.4e-54 181.6 0.0 1.3e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Peptidase_S39 PF02122.10 EON97645.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase S39 MFS_1 PF07690.11 EON97646.1 - 1.2e-22 80.0 19.4 1.2e-22 80.0 13.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97646.1 - 5.4e-07 28.5 2.0 5.4e-07 28.5 1.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TPT PF03151.11 EON97650.1 - 8.4e-27 93.6 14.7 8.4e-27 93.6 10.2 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EON97650.1 - 0.14 12.2 26.5 0.42 10.6 1.3 3.0 3 0 0 3 3 3 0 EamA-like transporter family Vma12 PF11712.3 EON97650.1 - 3 7.5 0.0 3 7.5 0.0 3.0 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ras PF00071.17 EON97651.1 - 3.5e-39 133.7 0.0 6.4e-37 126.4 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EON97651.1 - 6.9e-17 62.0 0.0 9.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON97651.1 - 2.1e-09 36.8 0.0 3.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EON97651.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EON97651.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EON97651.1 - 0.025 13.7 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 EON97651.1 - 0.041 13.5 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EON97651.1 - 0.063 13.2 0.6 0.42 10.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EON97651.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EON97651.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EON97651.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain DAO PF01266.19 EON97652.1 - 5.9e-55 186.6 1.4 6.7e-55 186.4 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EON97652.1 - 0.00042 20.4 0.4 0.012 15.6 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97652.1 - 0.00093 19.1 0.8 0.0026 17.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON97652.1 - 0.0022 17.8 0.4 0.0083 16.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON97652.1 - 0.0024 16.9 1.0 0.2 10.6 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Mqo PF06039.10 EON97652.1 - 0.0036 15.5 0.1 2 6.4 0.0 2.6 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.2 EON97652.1 - 0.17 10.9 4.0 1.1 8.2 2.8 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EON97652.1 - 0.41 9.4 4.4 0.58 8.9 3.1 1.3 1 1 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.16 EON97653.1 - 8.7e-06 24.7 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ammonium_transp PF00909.16 EON97654.1 - 1.1e-70 238.1 29.5 1.2e-70 238.0 20.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TcdA_TcdB_pore PF12920.2 EON97654.1 - 4.8 4.9 4.4 6.8 4.4 3.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Glyco_transf_22 PF03901.12 EON97655.1 - 2.4e-84 283.7 9.3 2.7e-84 283.5 6.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PDR_assoc PF08370.6 EON97655.1 - 1.3 8.5 8.5 0.97 8.9 0.8 2.9 2 0 0 2 2 2 0 Plant PDR ABC transporter associated CBS PF00571.23 EON97656.1 - 1.3e-29 101.7 6.8 1.1e-13 50.7 0.1 4.3 4 0 0 4 4 4 4 CBS domain IMPDH PF00478.20 EON97656.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain GSHPx PF00255.14 EON97657.1 - 2.1e-41 139.6 0.0 2.6e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EON97657.1 - 0.00015 21.2 0.0 0.00042 19.8 0.0 1.6 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EON97657.1 - 0.00027 20.6 0.1 0.00052 19.6 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 EON97657.1 - 0.0007 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) TIMELESS PF04821.9 EON97658.1 - 1.6e-92 309.5 1.8 2.3e-92 309.0 0.1 2.2 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 EON97658.1 - 2.2e-33 116.0 36.2 2.2e-33 116.0 25.1 3.8 2 1 0 2 2 2 1 Timeless protein C terminal region LacAB_rpiB PF02502.13 EON97659.1 - 1.1e-41 141.7 0.4 1.3e-41 141.5 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Acetyltransf_1 PF00583.19 EON97660.1 - 8.7e-10 38.4 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EON97660.1 - 1e-09 38.5 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EON97660.1 - 3.4e-08 33.5 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON97660.1 - 1.3e-05 25.3 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EON97660.1 - 3e-05 23.8 0.1 6.6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EON97660.1 - 0.00056 20.0 0.0 0.00085 19.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON97660.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein WSC PF01822.14 EON97661.1 - 5.3e-22 77.5 17.6 5.6e-18 64.6 8.7 2.1 2 0 0 2 2 2 2 WSC domain PRKCSH_1 PF13015.1 EON97661.1 - 0.052 13.0 1.3 0.85 9.0 0.3 2.3 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein TFIIIC_sub6 PF10419.4 EON97661.1 - 0.14 11.6 0.6 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 TFIIIC subunit Glycos_transf_4 PF00953.16 EON97662.1 - 2.9e-30 105.1 14.4 2.9e-30 105.1 10.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF1754 PF08555.5 EON97663.1 - 5.1e-11 43.0 18.1 5.1e-11 43.0 12.5 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MSA_2 PF00985.12 EON97663.1 - 0.014 15.5 4.9 0.019 15.0 3.4 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Adaptin_binding PF10199.4 EON97663.1 - 0.43 10.8 12.4 0.65 10.2 8.6 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC27 PF09507.5 EON97663.1 - 0.59 9.2 20.0 0.69 9.0 13.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PLRV_ORF5 PF01690.12 EON97663.1 - 1.1 8.3 8.6 1.3 8.1 6.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SRP-alpha_N PF04086.8 EON97663.1 - 1.2 8.4 13.9 1.5 8.1 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Trypan_PARP PF05887.6 EON97663.1 - 2.1 8.1 8.9 2.7 7.8 6.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prothymosin PF03247.9 EON97663.1 - 3.4 7.8 22.0 0.75 9.9 12.7 1.7 1 1 1 2 2 2 0 Prothymosin/parathymosin family HCO3_cotransp PF00955.16 EON97664.1 - 5.8e-71 239.6 12.4 3.3e-42 144.8 3.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF1537 PF07005.6 EON97665.1 - 6.6e-26 91.3 1.0 9.2e-26 90.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 MCPsignal PF00015.16 EON97665.1 - 0.0055 16.2 0.8 0.0094 15.5 0.5 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Glu_syn_central PF04898.9 EON97665.1 - 0.091 11.9 0.8 0.2 10.9 0.5 1.5 1 1 0 1 1 1 0 Glutamate synthase central domain DUF1561 PF07598.6 EON97665.1 - 0.19 9.6 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) NARP1 PF12569.3 EON97666.1 - 1e-199 664.6 27.8 4.1e-198 659.3 14.0 2.7 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EON97666.1 - 3.5e-20 71.4 26.6 1.6e-05 24.4 0.1 7.3 5 1 2 8 8 8 6 TPR repeat TPR_16 PF13432.1 EON97666.1 - 4.2e-19 68.6 34.0 0.00064 20.3 0.0 9.2 6 1 5 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EON97666.1 - 7.4e-19 66.5 19.9 0.006 17.1 0.0 11.7 8 2 4 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EON97666.1 - 9.4e-17 61.1 32.8 0.0013 18.9 0.1 8.7 7 2 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EON97666.1 - 2.3e-15 55.1 31.9 0.00054 19.6 0.1 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EON97666.1 - 3.2e-14 51.8 14.6 0.0088 16.1 0.0 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON97666.1 - 7.8e-11 41.7 20.7 0.0096 15.8 0.1 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EON97666.1 - 1.4e-10 40.8 8.5 0.00051 19.8 0.1 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EON97666.1 - 2.8e-09 36.7 8.7 0.067 13.0 0.1 6.1 6 0 0 6 6 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EON97666.1 - 4.2e-09 35.6 30.6 3.1e-05 23.3 0.1 8.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EON97666.1 - 2e-07 30.2 7.6 0.0022 17.6 0.0 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EON97666.1 - 0.0001 21.4 17.2 0.059 12.4 2.4 4.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EON97666.1 - 0.001 18.9 8.3 1.7 8.6 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON97666.1 - 0.0018 17.8 7.5 4 7.4 0.0 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 EON97666.1 - 0.04 14.2 0.7 0.04 14.2 0.5 3.5 4 0 0 4 4 3 0 Bacterial transcriptional activator domain NAM-associated PF14303.1 EON97666.1 - 0.41 10.9 18.8 0.34 11.2 0.1 2.9 3 0 0 3 3 2 0 No apical meristem-associated C-terminal domain TPR_4 PF07721.9 EON97666.1 - 4.3 8.0 10.7 3.8 8.2 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EON97666.1 - 5.2 6.9 11.6 0.34 10.7 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat adh_short PF00106.20 EON97667.1 - 5e-16 59.0 0.0 7.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97667.1 - 1.1e-06 28.4 0.1 3.5e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EON97667.1 - 0.064 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PEMT PF04191.8 EON97668.1 - 1.5e-55 185.7 9.2 4.1e-35 120.0 0.6 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase HEAT_2 PF13646.1 EON97668.1 - 3.9e-27 94.3 5.6 9.7e-14 51.4 0.2 3.6 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EON97668.1 - 2.4e-16 58.4 3.9 0.042 14.3 0.1 6.8 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EON97668.1 - 0.0024 18.3 13.5 0.032 14.7 0.4 5.2 3 2 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EON97668.1 - 0.31 11.2 7.6 7.6 6.9 0.0 5.4 7 0 0 7 7 7 0 HEAT repeat rRNA_processing PF08524.6 EON97669.1 - 0.0025 17.6 32.7 0.016 14.9 10.9 2.1 1 1 1 2 2 2 2 rRNA processing Chitin_synth_2 PF03142.10 EON97670.1 - 9.6e-258 855.8 1.2 2.6e-257 854.4 1.1 1.5 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 EON97670.1 - 2.3e-154 515.1 0.0 3e-154 514.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EON97670.1 - 3.2e-18 65.2 0.2 2.3e-17 62.5 0.1 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EON97670.1 - 1.1e-16 60.3 0.6 7.2e-12 44.9 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EON97670.1 - 6e-16 58.9 0.3 1.6e-12 47.7 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EON97670.1 - 3.2e-15 56.3 6.1 3.2e-15 56.3 4.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EON97670.1 - 3.1e-05 23.7 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EON97670.1 - 0.0011 18.9 0.4 0.0038 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EON97670.1 - 0.0092 16.1 0.3 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF1622 PF07784.6 EON97670.1 - 0.012 15.2 1.4 6.3 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) Glyco_transf_21 PF13506.1 EON97670.1 - 0.013 14.8 0.3 0.045 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_29 PF13555.1 EON97670.1 - 0.029 13.9 0.1 0.092 12.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EON97670.1 - 0.097 12.3 0.4 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EON97670.1 - 0.11 11.6 0.4 0.45 9.7 0.3 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GFO_IDH_MocA PF01408.17 EON97671.1 - 1.8e-11 44.5 2.2 9.4e-11 42.2 1.5 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EON97671.1 - 0.0063 16.8 0.1 0.016 15.6 0.1 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Pterin_bind PF00809.17 EON97671.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme PNTB PF02233.11 EON97672.1 - 2.7e-158 527.5 26.5 2.7e-158 527.5 18.4 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EON97672.1 - 2.5e-54 183.3 0.4 4.5e-54 182.4 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EON97672.1 - 1.1e-50 171.1 0.1 2.8e-50 169.8 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EON97672.1 - 1.6e-30 105.1 2.7 1.6e-30 105.1 1.9 5.7 4 2 3 7 7 7 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EON97672.1 - 0.0018 17.4 0.1 1.4 7.9 0.0 3.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EON97672.1 - 0.005 16.3 0.2 0.023 14.2 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EON97672.1 - 0.015 15.1 0.4 0.054 13.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 EON97672.1 - 0.021 13.9 0.1 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Shikimate_DH PF01488.15 EON97672.1 - 0.064 13.3 3.7 2.9 7.9 0.0 3.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EON97672.1 - 0.12 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EON97672.1 - 0.17 11.4 0.0 0.45 10.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EON97672.1 - 5.6 7.0 9.1 0.78 9.8 1.8 3.1 3 1 0 3 3 2 0 NAD(P)-binding Rossmann-like domain DUF2235 PF09994.4 EON97673.1 - 1.1e-36 126.6 0.8 1.4e-36 126.3 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EON97673.1 - 0.0027 17.4 0.0 0.0045 16.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_16 PF10294.4 EON97674.1 - 4.9e-11 42.3 0.0 6.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase BCAS3 PF12490.3 EON97675.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 KorB_C PF06613.6 EON97676.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain 3HCDH_N PF02737.13 EON97677.1 - 8.8e-20 71.1 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EON97677.1 - 8.1e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF1772 PF08592.6 EON97678.1 - 0.28 10.9 8.5 0.036 13.7 2.9 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) MscS_TM PF12794.2 EON97678.1 - 1.1 7.8 5.4 11 4.4 1.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Chitin_bind_3 PF03067.10 EON97679.1 - 0.0088 16.3 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 Chitin binding domain Serglycin PF04360.7 EON97679.1 - 0.083 12.6 10.0 0.19 11.4 0.5 2.4 2 0 0 2 2 2 0 Serglycin E1_DerP2_DerF2 PF02221.10 EON97679.1 - 0.14 12.4 0.2 0.93 9.7 0.0 2.4 2 1 0 2 2 2 0 ML domain FAD_binding_2 PF00890.19 EON97680.1 - 6.2e-40 137.3 0.0 1.9e-39 135.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON97680.1 - 8.7e-14 51.1 0.4 1.9e-10 40.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EON97680.1 - 1.5e-10 40.7 1.1 2.1e-10 40.2 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON97680.1 - 1.9e-07 29.9 0.9 6.2e-06 24.9 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 EON97680.1 - 2.5e-06 27.5 1.8 0.00023 21.0 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON97680.1 - 4.8e-05 23.5 3.6 0.0034 17.4 2.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON97680.1 - 5.6e-05 22.1 7.9 0.00044 19.2 4.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EON97680.1 - 0.0001 22.2 4.2 0.00015 21.7 2.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EON97680.1 - 0.0011 18.0 4.7 0.0021 17.1 3.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EON97680.1 - 0.0013 19.0 1.6 0.051 13.9 1.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON97680.1 - 0.0068 15.3 5.3 0.47 9.3 2.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 EON97680.1 - 0.0069 15.4 0.9 0.02 13.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Alk_phosphatase PF00245.15 EON97681.1 - 5.3e-62 209.8 0.0 2.2e-61 207.8 0.0 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EON97681.1 - 2.4e-06 27.1 0.1 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EON97681.1 - 5.5e-06 25.7 0.0 9.7e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EON97681.1 - 0.012 14.0 0.2 0.02 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 EON97681.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GMC_oxred_N PF00732.14 EON97682.1 - 2.3e-25 89.3 0.0 2.8e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EON97682.1 - 0.0031 17.5 0.0 0.008 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EON97682.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EON97682.1 - 0.013 14.6 0.4 0.027 13.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EON97682.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EON97682.1 - 0.034 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EON97682.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EON97682.1 - 0.17 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EON97682.1 - 0.2 10.1 0.0 0.2 10.1 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_4 PF01565.18 EON97683.1 - 6.4e-37 126.1 4.1 6.4e-37 126.1 2.9 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EON97683.1 - 2.4e-05 24.1 0.3 6.3e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Coiled PF05710.7 EON97683.1 - 1.1 9.7 5.4 1.5 9.3 2.9 1.8 1 1 1 2 2 2 0 Coiled coil Glyco_hydro_76 PF03663.9 EON97684.1 - 3.4e-137 457.7 12.1 4.2e-137 457.4 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EON97684.1 - 0.8 8.6 8.7 0.48 9.4 0.2 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 G0-G1_switch_2 PF15103.1 EON97685.1 - 0.36 11.0 6.0 0.44 10.8 0.4 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 SR-25 PF10500.4 EON97685.1 - 0.37 10.2 16.0 0.51 9.7 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cas_Csy4 PF09618.5 EON97685.1 - 6.2 6.5 14.0 0.069 12.9 1.9 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csy4) BSP PF04450.7 EON97687.1 - 7.9e-79 263.8 0.0 9.4e-79 263.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EON97687.1 - 2.2e-07 30.9 0.0 2e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase MA superfamily Amidohydro_1 PF01979.15 EON97688.1 - 1.2e-44 153.3 0.0 1.4e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EON97688.1 - 1.7e-08 34.1 6.2 1.4e-05 24.4 0.1 3.9 3 1 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 EON97688.1 - 5.5e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EON97688.1 - 8e-05 22.8 0.5 0.029 14.4 0.3 2.3 2 0 0 2 2 2 2 Amidohydrolase Ribosomal_S17e PF00833.13 EON97689.1 - 2e-58 195.4 0.4 2.4e-58 195.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EON97689.1 - 0.028 15.1 0.0 0.038 14.6 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal DUF1757 PF08560.5 EON97690.1 - 5.8e-06 26.0 0.0 8.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Hydrolase PF00702.21 EON97691.1 - 2.7e-18 67.1 0.0 1.7e-14 54.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EON97691.1 - 1.1e-17 63.8 0.1 3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EON97691.1 - 1.1e-12 48.5 0.1 9.7e-12 45.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON97691.1 - 1.5e-11 44.0 0.0 8.7e-11 41.6 0.0 2.3 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EON97691.1 - 0.00042 19.9 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EON97691.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Methyltransf_2 PF00891.13 EON97692.1 - 6.4e-29 100.8 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EON97692.1 - 0.0066 16.2 0.0 0.072 12.9 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain TIM PF00121.13 EON97693.1 - 1.1e-56 191.6 0.0 1.3e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase p450 PF00067.17 EON97694.1 - 7e-34 117.1 0.0 9e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.22 EON97695.1 - 0.0058 15.9 0.4 0.0058 15.9 0.3 2.3 2 0 0 2 2 2 1 GATA zinc finger TATR PF03430.8 EON97695.1 - 0.56 8.7 5.8 0.8 8.2 4.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DDE_Tnp_1 PF01609.16 EON97695.1 - 0.66 9.4 5.5 0.082 12.4 0.7 1.7 2 0 0 2 2 2 0 Transposase DDE domain Paramyxo_ncap PF00973.14 EON97695.1 - 6.1 5.4 9.9 9.6 4.7 6.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Metallophos PF00149.23 EON97696.1 - 4.3e-05 22.9 1.0 4.3e-05 22.9 0.7 2.6 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EON97696.1 - 0.00016 21.5 0.8 0.00043 20.1 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cu-oxidase PF00394.17 EON97697.1 - 1.7e-32 112.4 0.1 6.7e-32 110.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EON97697.1 - 4.3e-14 52.2 1.2 1.5e-13 50.5 0.1 2.2 2 1 0 2 2 2 1 Multicopper oxidase DNA_pol_A_exo1 PF01612.15 EON97699.1 - 1.8e-15 56.9 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Cyclase_polyket PF04673.7 EON97699.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Polyketide synthesis cyclase EF-hand_7 PF13499.1 EON97700.1 - 3.3e-29 100.8 12.4 2e-13 50.2 0.7 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EON97700.1 - 2.7e-24 82.5 14.0 3.8e-08 32.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EON97700.1 - 1.3e-23 80.7 4.4 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EON97700.1 - 6.7e-17 59.9 14.8 2.5e-05 23.3 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EON97700.1 - 2.6e-14 52.5 13.4 1.7e-05 24.3 0.9 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EON97700.1 - 3.3e-09 36.4 8.6 0.0039 16.9 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EON97700.1 - 7.3e-05 22.6 0.5 0.022 14.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EON97700.1 - 0.0012 18.9 2.4 0.37 10.8 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EON97700.1 - 0.0039 16.8 3.7 0.33 10.6 0.1 4.0 4 0 0 4 4 4 1 EF hand Toprim PF01751.17 EON97700.1 - 0.011 15.6 0.0 3.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Toprim domain DUF1679 PF07914.6 EON97700.1 - 0.016 13.8 0.6 1.3 7.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 EON97700.1 - 0.02 14.9 0.1 2.9 7.9 0.0 3.1 3 1 1 4 4 4 0 EF hand peroxidase PF00141.18 EON97702.1 - 2.4e-19 69.7 0.0 3.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4246 PF14033.1 EON97703.1 - 2.7e-185 616.7 4.7 4.1e-185 616.1 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EON97703.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CDC45 PF02724.9 EON97703.1 - 0.47 8.4 5.3 0.69 7.8 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.15 EON97704.1 - 2.8e-08 32.1 0.0 1.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein Hydantoinase_A PF01968.13 EON97704.1 - 0.043 12.9 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MreB_Mbl PF06723.8 EON97704.1 - 0.069 11.7 0.1 0.14 10.7 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein HAD_2 PF13419.1 EON97705.1 - 2.1e-11 44.3 0.0 3.3e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EON97705.1 - 5.6e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EON97705.1 - 0.0018 18.7 0.0 0.26 11.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Porphobil_deam PF01379.15 EON97706.1 - 4.7e-76 254.4 0.0 6.3e-76 254.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EON97706.1 - 5e-17 61.7 0.1 1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain F-box-like PF12937.2 EON97707.1 - 0.0085 15.7 0.8 0.023 14.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like DUF663 PF04950.7 EON97708.1 - 2e-90 302.8 0.1 2e-90 302.8 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EON97708.1 - 2.4e-27 94.2 0.1 3e-26 90.7 0.0 2.6 3 0 0 3 3 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 EON97708.1 - 8.4e-06 25.9 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON97708.1 - 9.7e-06 25.6 0.0 4.2e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 EON97708.1 - 1e-05 25.0 0.7 0.0011 18.4 0.0 2.7 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EON97708.1 - 0.00026 20.7 0.0 0.00067 19.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 EON97708.1 - 0.00032 21.0 1.2 0.0019 18.4 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA PF00004.24 EON97708.1 - 0.00038 20.6 0.0 0.00092 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EON97708.1 - 0.00041 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EON97708.1 - 0.00044 20.7 0.4 0.0017 18.8 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein PduV-EutP PF10662.4 EON97708.1 - 0.0008 18.9 0.0 0.002 17.6 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EON97708.1 - 0.00093 18.9 0.4 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EON97708.1 - 0.0012 18.2 0.0 0.0036 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON97708.1 - 0.0021 18.8 0.0 0.0021 18.8 0.0 4.6 3 1 1 4 4 2 1 AAA domain AAA_14 PF13173.1 EON97708.1 - 0.0023 17.8 0.0 0.007 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EON97708.1 - 0.0024 17.5 0.1 0.0085 15.8 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EON97708.1 - 0.0026 17.6 0.2 0.0095 15.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EON97708.1 - 0.0058 16.9 0.0 0.0058 16.9 0.0 5.0 4 1 1 5 5 5 1 AAA domain RNA_helicase PF00910.17 EON97708.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EON97708.1 - 0.012 15.3 0.3 0.026 14.2 0.2 1.6 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EON97708.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EON97708.1 - 0.012 15.1 0.1 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EON97708.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EON97708.1 - 0.014 14.3 0.2 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 EON97708.1 - 0.027 13.6 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EON97708.1 - 0.064 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EON97708.1 - 0.78 9.6 0.0 0.78 9.6 0.0 3.1 2 1 0 2 2 1 0 AAA domain Ank_5 PF13857.1 EON97709.1 - 2.1e-10 40.4 0.0 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON97709.1 - 9.4e-06 26.0 0.0 6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON97709.1 - 0.012 15.7 0.1 0.066 13.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 EON97709.1 - 0.02 15.2 0.1 0.087 13.1 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EON97709.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat R3H PF01424.17 EON97709.1 - 0.13 11.9 0.3 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 R3H domain GalKase_gal_bdg PF10509.4 EON97710.1 - 4.7e-21 73.8 0.0 8.9e-21 72.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EON97710.1 - 2.3e-12 46.9 0.1 8.6e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EON97710.1 - 2.7e-12 46.5 1.3 7.3e-12 45.1 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Sigma70_r4 PF04545.11 EON97710.1 - 0.076 12.3 0.0 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 EON97710.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DUF1223 PF06764.6 EON97711.1 - 8.1e-42 143.3 0.0 9.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) SH3_9 PF14604.1 EON97712.1 - 2.8e-05 23.5 0.1 0.01 15.4 0.0 3.2 2 1 0 2 2 2 2 Variant SH3 domain RRM_6 PF14259.1 EON97713.1 - 2e-13 50.0 2.8 5.9e-12 45.3 0.1 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97713.1 - 1.1e-09 37.9 0.2 3.7e-08 33.0 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EON97713.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EON97713.1 - 2e-06 27.3 0.5 3e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EON97713.1 - 0.0063 16.2 0.0 0.083 12.6 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif LRS4 PF10422.4 EON97713.1 - 0.015 14.6 2.7 0.025 13.9 1.9 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1330 PF07045.6 EON97713.1 - 0.12 12.2 0.6 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Pkinase PF00069.20 EON97714.1 - 1.5e-15 57.0 0.0 4.8e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97714.1 - 3.1e-09 36.2 0.0 2.4e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EON97714.1 - 0.047 12.4 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1996 PF09362.5 EON97715.1 - 1.2e-78 264.0 2.8 1.4e-78 263.8 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lys PF00062.15 EON97715.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Abhydrolase_3 PF07859.8 EON97716.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aconitase PF00330.15 EON97717.1 - 4.4e-183 609.0 0.0 5.4e-183 608.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EON97717.1 - 2.2e-45 153.9 0.0 4e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Amidohydro_4 PF13147.1 EON97719.1 - 4.8e-21 76.0 0.0 5.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EON97719.1 - 1.8e-13 50.0 0.1 5e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EON97719.1 - 2.2e-08 34.1 0.1 0.0031 17.2 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EON97719.1 - 0.00058 19.1 0.0 0.45 9.6 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EON97719.1 - 0.072 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Amidohydro_2 PF04909.9 EON97719.1 - 0.079 12.4 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase FKBP_C PF00254.23 EON97720.1 - 2.5e-28 97.9 0.0 3.1e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NMT1 PF09084.6 EON97721.1 - 2e-13 50.4 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EON97721.1 - 0.004 16.5 0.0 0.0069 15.8 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 EON97721.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein AA_permease_2 PF13520.1 EON97722.1 - 2.6e-93 312.9 40.9 3.7e-93 312.3 28.4 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON97722.1 - 2.9e-18 65.4 32.6 3.7e-18 65.1 22.6 1.1 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.8 EON97723.1 - 3.8e-70 235.6 1.6 3.8e-70 235.6 1.1 2.3 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EON97723.1 - 1.5e-21 76.5 3.6 1.5e-21 76.5 2.5 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus DbpA PF03880.10 EON97724.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain UPF0261 PF06792.6 EON97725.1 - 5.1e-131 436.8 0.2 6.1e-131 436.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) APH PF01636.18 EON97728.1 - 4.2e-07 29.9 0.5 0.00011 21.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EON97728.1 - 4.6e-06 25.8 0.0 8.1e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EON97728.1 - 1.5e-05 24.4 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EON97728.1 - 0.00027 20.5 0.4 0.2 11.2 0.1 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.20 EON97728.1 - 0.014 14.5 0.2 0.021 13.9 0.2 1.5 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 EON97728.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Prim-Pol PF09250.6 EON97728.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal EcKinase PF02958.15 EON97728.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Cyto_heme_lyase PF01265.12 EON97729.1 - 7.7e-75 251.8 0.1 8.8e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PRKCSH-like PF12999.2 EON97730.1 - 4.9e-38 130.4 11.6 1.6e-22 79.9 0.5 3.3 4 1 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EON97730.1 - 4.6e-31 107.3 0.6 4.6e-31 107.3 0.4 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EON97730.1 - 3.6e-11 43.7 1.0 1.1e-10 42.2 0.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.5 EON97730.1 - 0.00065 19.5 0.3 0.00065 19.5 0.2 1.7 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain GAS PF13851.1 EON97730.1 - 0.024 13.8 10.0 0.15 11.2 3.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.9 EON97730.1 - 0.044 13.7 6.3 0.066 13.1 1.7 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.15 EON97730.1 - 0.06 13.1 19.7 0.05 13.3 4.3 3.6 3 1 1 4 4 4 0 Prefoldin subunit Snapin_Pallidin PF14712.1 EON97730.1 - 0.14 12.5 7.1 0.33 11.3 0.0 3.3 3 0 0 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.7 EON97730.1 - 0.17 12.1 4.8 0.32 11.2 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.7 EON97730.1 - 0.21 10.8 3.7 1.9 7.7 0.4 2.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus V_ATPase_I PF01496.14 EON97730.1 - 0.39 8.5 4.6 0.66 7.7 3.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 EON97730.1 - 0.52 9.2 5.1 1.2 8.1 3.5 1.5 1 0 0 1 1 1 0 CASP C terminal Fzo_mitofusin PF04799.8 EON97730.1 - 0.63 9.4 4.4 7.5 5.9 0.6 2.4 2 0 0 2 2 2 0 fzo-like conserved region DUF3837 PF12939.2 EON97730.1 - 0.71 9.9 3.6 0.43 10.6 0.1 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF3837) DUF3584 PF12128.3 EON97730.1 - 1.1 6.5 15.0 0.034 11.4 6.4 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HR1 PF02185.11 EON97730.1 - 1.2 8.9 7.9 12 5.6 2.4 2.6 2 0 0 2 2 2 0 Hr1 repeat Osmo_CC PF08946.5 EON97730.1 - 1.2 9.1 9.9 0.24 11.4 2.6 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Fib_alpha PF08702.5 EON97730.1 - 1.3 9.1 7.0 2.4 8.2 0.1 2.5 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family Effector_1 PF04518.7 EON97730.1 - 2.1 7.2 3.7 8.5 5.2 0.7 2.3 2 0 0 2 2 2 0 Effector from type III secretion system DUF4047 PF13256.1 EON97730.1 - 3.4 7.6 9.5 5.4 6.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) BLOC1_2 PF10046.4 EON97730.1 - 4.7 7.4 8.9 5 7.3 0.3 2.6 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.1 EON97730.1 - 7.2 5.4 17.0 3.5 6.4 8.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 EON97730.1 - 8.9 6.0 9.9 1.8 8.2 0.5 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Acetyltransf_1 PF00583.19 EON97731.1 - 1.4e-14 53.8 0.0 2.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EON97731.1 - 1.3e-12 48.0 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EON97731.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON97731.1 - 0.00035 20.2 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EON97731.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MPLKIP PF15502.1 EON97731.1 - 0.1 13.2 0.2 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein TIM-br_sig_trns PF09370.5 EON97733.1 - 5.9e-137 455.0 0.6 6.7e-137 454.8 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EON97733.1 - 2.5e-05 23.5 0.1 3.6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FeoA PF04023.9 EON97733.1 - 0.043 13.7 0.0 0.6 10.1 0.0 2.4 1 1 0 1 1 1 0 FeoA domain Pectate_lyase_3 PF12708.2 EON97734.1 - 2.3e-84 283.0 15.3 2e-67 227.6 2.4 3.4 2 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EON97734.1 - 7.1e-07 28.5 1.4 0.03 13.7 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EON97734.1 - 0.0084 15.8 12.4 0.012 15.3 4.3 3.0 2 1 0 2 2 2 1 Right handed beta helix region Aldo_ket_red PF00248.16 EON97735.1 - 7.4e-68 228.4 0.0 9.1e-68 228.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RhgB_N PF09284.5 EON97736.1 - 5.2e-80 268.3 0.4 5.2e-80 268.3 0.3 1.7 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EON97736.1 - 4.2e-58 195.6 0.0 1.1e-57 194.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EON97736.1 - 6.2e-18 64.7 2.7 1.3e-17 63.7 1.9 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EON97736.1 - 0.0011 18.9 9.3 0.0014 18.6 3.4 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain PEGA PF08308.6 EON97736.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 PEGA domain DUF2012 PF09430.5 EON97736.1 - 0.047 13.5 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Sugar_tr PF00083.19 EON97737.1 - 9e-53 179.4 3.7 3.5e-51 174.1 2.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Folate_carrier PF01770.13 EON97737.1 - 0.051 12.0 0.0 0.067 11.7 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier FAT PF02259.18 EON97738.1 - 2.2e-125 418.3 1.2 3.6e-125 417.6 0.4 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EON97738.1 - 8.3e-63 211.9 0.5 1.8e-62 210.9 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EON97738.1 - 3.9e-55 186.1 6.1 4.1e-32 111.3 0.1 5.2 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EON97738.1 - 1.3e-42 143.9 1.7 3.3e-42 142.6 0.1 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EON97738.1 - 1.5e-20 73.2 5.4 0.00029 21.0 0.0 8.6 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.17 EON97738.1 - 9.3e-15 53.3 21.6 0.0027 17.6 0.0 11.3 13 0 0 13 13 12 4 HEAT repeat FATC PF02260.15 EON97738.1 - 5.2e-14 51.3 0.1 1.4e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EON97738.1 - 9.8e-12 45.0 17.4 0.00028 21.2 0.1 11.0 9 3 4 13 13 12 3 HEAT-like repeat Adaptin_N PF01602.15 EON97738.1 - 1.3e-06 27.0 3.8 0.047 12.0 0.0 4.7 3 3 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EON97738.1 - 1.2e-05 25.5 1.1 63 4.0 0.0 6.8 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EON97738.1 - 9e-05 21.9 0.9 1.4 8.1 0.0 5.5 6 1 0 6 6 6 1 CLASP N terminal GCIP PF13324.1 EON97739.1 - 0.00027 20.2 0.4 0.00088 18.5 0.2 1.9 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EON97739.1 - 0.0028 17.3 0.4 0.0056 16.3 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region CobT PF06213.7 EON97739.1 - 0.014 14.5 3.9 0.026 13.6 2.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop25 PF09805.4 EON97739.1 - 0.32 11.0 3.0 0.54 10.3 2.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CENP-B_dimeris PF09026.5 EON97739.1 - 0.76 10.0 7.3 2.8 8.2 4.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EON97739.1 - 2.6 6.6 9.8 3.9 6.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EON97739.1 - 5 6.6 8.2 8.3 5.9 5.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin SnoaL_4 PF13577.1 EON97740.1 - 2.1e-05 24.4 2.3 3.7e-05 23.6 1.6 1.4 1 0 0 1 1 1 1 SnoaL-like domain ING PF12998.2 EON97740.1 - 0.0035 17.6 0.4 0.025 14.8 0.0 2.6 2 1 1 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EON97740.1 - 0.0038 16.8 1.7 0.0071 16.0 1.2 1.4 1 0 0 1 1 1 1 PHD-finger SnoaL_2 PF12680.2 EON97740.1 - 0.0059 17.0 0.6 0.015 15.6 0.4 1.6 1 0 0 1 1 1 1 SnoaL-like domain TRAM_LAG1_CLN8 PF03798.11 EON97741.1 - 3.4e-22 78.9 28.1 3.3e-21 75.7 17.7 2.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EON97741.1 - 3.6e-22 77.6 0.5 1e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF4408 PF14364.1 EON97741.1 - 0.037 13.5 0.5 0.037 13.5 0.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4408) MIF4G PF02854.14 EON97742.1 - 6.7e-27 94.2 1.4 1.8e-26 92.9 0.2 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EON97742.1 - 8.2e-21 73.8 0.1 3.3e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 MA3 domain Glyco_hydro_16 PF00722.16 EON97744.1 - 8.5e-12 44.7 0.8 1.5e-11 43.9 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Gly-rich_Ago1 PF12764.2 EON97745.1 - 0.27 11.9 0.1 0.27 11.9 0.0 3.2 3 1 1 4 4 4 0 Glycine-rich region of argonaut ABC_tran PF00005.22 EON97746.1 - 3.4e-18 66.2 0.0 6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EON97746.1 - 5.2e-14 52.3 0.1 7.1e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EON97746.1 - 4.8e-06 25.9 0.1 6.1e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EON97746.1 - 0.00078 19.3 0.4 0.011 15.6 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Methyltransf_11 PF08241.7 EON97747.1 - 2.2e-05 24.8 0.0 3.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EON97747.1 - 0.00014 20.9 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 EON97747.1 - 0.00096 19.4 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EON97747.1 - 0.0021 16.5 0.0 0.0028 16.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 EON97747.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dus PF01207.12 EON97748.1 - 1.1e-55 188.7 0.0 2.8e-55 187.3 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF849 PF05853.7 EON97748.1 - 0.14 11.0 0.1 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) CBP4 PF07960.6 EON97748.1 - 1.3 8.6 7.6 2.9 7.5 3.8 2.3 2 0 0 2 2 2 0 CBP4 STb_secrete PF09075.5 EON97750.1 - 0.052 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory PalH PF08733.5 EON97751.1 - 1.6e-112 375.8 0.0 1.8e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.1 EON97751.1 - 0.0036 17.2 6.0 2 8.4 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4231) SPC25 PF06703.6 EON97751.1 - 2 7.9 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DPM2 PF07297.7 EON97752.1 - 3.9e-31 107.1 2.5 4.6e-31 106.9 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.1 EON97752.1 - 0.00035 20.4 0.7 0.00035 20.4 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) PIG-P PF08510.7 EON97752.1 - 0.00045 19.8 1.2 0.00048 19.7 0.8 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.1 EON97752.1 - 0.0027 17.2 1.4 0.058 13.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF4083 PF13314.1 EON97752.1 - 0.0043 16.8 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF1049 PF06305.6 EON97752.1 - 0.05 13.0 0.2 0.05 13.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DiS_P_DiS PF06750.8 EON97752.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Herpes_UL43 PF05072.8 EON97752.1 - 0.12 11.0 0.6 0.16 10.7 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein CBF PF03914.12 EON97753.1 - 1.3e-44 151.5 0.2 3e-44 150.3 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Ribosomal_L6 PF00347.18 EON97754.1 - 7.7e-28 96.8 11.3 1.3e-14 54.4 2.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DHDPS PF00701.17 EON97755.1 - 2.5e-48 164.1 0.0 2.9e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HAD PF12710.2 EON97756.1 - 1.4e-08 35.1 0.0 3.7e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EON97756.1 - 0.12 12.5 0.0 1.3 9.1 0.0 2.5 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase APH PF01636.18 EON97757.1 - 2.8e-42 145.1 0.0 6.7e-42 143.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EON97757.1 - 3.8e-05 22.9 0.0 5.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EON97757.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EON97757.1 - 0.0036 16.6 0.0 0.048 13.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 EON97757.1 - 0.047 12.6 0.0 0.23 10.3 0.0 2.0 1 1 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.6 EON97757.1 - 0.076 11.6 0.0 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Rax2 PF12768.2 EON97758.1 - 8.2e-90 300.8 15.6 3.1e-84 282.5 0.0 4.9 4 1 0 5 5 5 4 Cortical protein marker for cell polarity Syndecan PF01034.15 EON97758.1 - 0.061 12.9 0.4 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Reg_prop PF07494.6 EON97758.1 - 6.3 7.1 14.4 8.7 6.7 0.1 6.3 8 0 0 8 8 8 0 Two component regulator propeller Cullin PF00888.17 EON97759.1 - 8.1e-48 163.3 0.0 1.7e-47 162.3 0.0 1.4 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 EON97759.1 - 9.8e-20 70.5 0.1 2.3e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-C2H2 PF00096.21 EON97760.1 - 0.0011 19.1 3.7 0.19 12.1 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON97760.1 - 0.0014 18.8 4.6 0.23 11.8 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EON97760.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 EON97760.1 - 0.028 13.6 0.3 0.048 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EON97760.1 - 0.029 14.2 2.3 4.5 7.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger bZIP_1 PF00170.16 EON97761.1 - 1.6e-08 34.3 17.5 6.7e-08 32.3 10.5 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EON97761.1 - 1.5e-06 28.3 15.5 4e-06 27.0 10.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EON97761.1 - 0.00018 21.2 22.2 0.0023 17.7 13.5 3.0 2 1 1 3 3 3 1 Basic region leucine zipper Endotoxin_N PF03945.9 EON97761.1 - 0.067 12.5 4.4 0.12 11.7 3.0 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF342 PF03961.8 EON97761.1 - 0.085 11.2 12.7 0.12 10.7 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ARD PF03079.9 EON97761.1 - 1.3 8.9 9.1 2.8 7.8 6.3 1.5 1 0 0 1 1 1 0 ARD/ARD' family V_ATPase_I PF01496.14 EON97761.1 - 3.4 5.3 8.2 5.2 4.7 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.5 EON97761.1 - 9.6 6.3 11.6 0.57 10.3 1.3 2.6 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Tim17 PF02466.14 EON97762.1 - 1.1e-25 90.1 0.1 1.4e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SPC25 PF06703.6 EON97763.1 - 3.6e-55 185.9 0.0 4.4e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short PF00106.20 EON97764.1 - 1.6e-26 93.2 2.9 2.2e-26 92.7 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97764.1 - 1.2e-14 54.7 0.9 1.4e-14 54.4 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON97764.1 - 8.3e-14 51.6 0.6 1.1e-13 51.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EON97764.1 - 4.8e-10 38.8 0.3 5.9e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EON97764.1 - 4.8e-05 22.8 0.2 7.8e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EON97764.1 - 0.00023 20.8 0.8 0.00023 20.8 0.6 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EON97764.1 - 0.0014 18.6 0.7 0.0025 17.8 0.5 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EON97764.1 - 0.013 15.4 1.5 0.019 15.0 1.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EON97764.1 - 0.092 11.6 3.2 0.22 10.4 2.3 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Pkinase PF00069.20 EON97765.1 - 3.9e-45 154.0 0.0 6.8e-45 153.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97765.1 - 6.1e-18 64.8 0.1 2.2e-17 63.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON97765.1 - 1.6e-06 27.3 0.1 0.00094 18.2 0.0 2.9 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EON97765.1 - 3.3e-05 23.7 0.0 0.062 13.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EON97765.1 - 0.0022 17.3 0.5 0.03 13.6 0.1 2.1 1 1 1 2 2 2 1 RIO1 family PsaA_PsaB PF00223.14 EON97765.1 - 0.061 11.3 0.0 0.099 10.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribul_P_3_epim PF00834.14 EON97766.1 - 3.6e-65 218.8 0.0 1.5e-64 216.7 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EON97766.1 - 0.031 13.6 0.2 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family P34-Arc PF04045.9 EON97767.1 - 1.2e-99 332.5 0.2 1.8e-99 331.9 0.1 1.3 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SNase PF00565.12 EON97767.1 - 1e-21 77.2 0.0 2.8e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rad51 PF08423.6 EON97768.1 - 1.8e-136 453.0 0.0 2.3e-136 452.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EON97768.1 - 5.1e-13 48.8 0.0 7.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EON97768.1 - 2.2e-07 30.9 0.9 5.7e-07 29.6 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EON97768.1 - 5.1e-07 29.0 0.0 7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EON97768.1 - 7.7e-06 25.1 0.0 1.5e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EON97768.1 - 0.048 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain GCV_T PF01571.16 EON97769.1 - 1.1e-63 214.4 0.0 1.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EON97769.1 - 1.3e-24 86.0 1.2 2.1e-24 85.3 0.8 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TFIIF_beta PF02270.10 EON97770.1 - 7.9e-67 225.9 0.2 9.7e-67 225.6 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 EON97770.1 - 0.035 14.1 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 IS66 C-terminal element Aminotran_5 PF00266.14 EON97771.1 - 3.5e-61 206.9 0.1 6.3e-61 206.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EON97771.1 - 4.5e-07 28.5 0.0 7.2e-07 27.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EON97771.1 - 2.3e-05 23.5 0.1 8.8e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Ofd1_CTDD PF10637.4 EON97772.1 - 3.8e-97 324.5 0.0 2.2e-90 302.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EON97772.1 - 1.7e-14 54.1 0.0 4.5e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkr1 PF08636.5 EON97773.1 - 1.3e-36 124.5 2.6 1.7e-36 124.1 1.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4233 PF14017.1 EON97773.1 - 0.063 13.1 1.0 0.088 12.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) DUF2244 PF10003.4 EON97773.1 - 0.12 11.7 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) OAD_gamma PF04277.8 EON97773.1 - 0.18 12.2 0.6 0.59 10.5 0.0 2.0 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NmrA PF05368.8 EON97774.1 - 4.9e-12 45.5 0.0 6.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON97774.1 - 4.9e-11 42.9 0.2 2.2e-10 40.8 0.0 2.1 3 0 0 3 3 3 1 NADH(P)-binding Saccharop_dh PF03435.13 EON97774.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EON97774.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family V-ATPase_H_N PF03224.9 EON97775.1 - 3.4e-76 256.3 0.0 4.6e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EON97775.1 - 5.3e-38 129.5 0.0 1.5e-37 128.1 0.0 1.8 1 0 0 1 1 1 1 V-ATPase subunit H Med4 PF10018.4 EON97775.1 - 0.074 12.4 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Glycophorin_A PF01102.13 EON97777.1 - 0.0011 18.7 0.9 0.0031 17.2 0.4 1.9 2 0 0 2 2 2 1 Glycophorin A SKG6 PF08693.5 EON97777.1 - 0.014 14.7 4.0 0.04 13.2 2.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EON97777.1 - 1.1 8.9 3.0 3.1 7.5 2.1 1.7 1 0 0 1 1 1 0 Syndecan domain TMEM51 PF15345.1 EON97777.1 - 3 7.4 5.4 4.3 6.9 0.0 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 Nup160 PF11715.3 EON97778.1 - 3.3e-95 319.2 0.2 5.1e-95 318.6 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF106 PF01956.11 EON97779.1 - 1.4e-47 161.3 0.9 1.9e-47 160.9 0.6 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Ribosomal_L21p PF00829.16 EON97780.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein MMS19_N PF14500.1 EON97781.1 - 1.8e-47 161.8 0.0 2.6e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CRM1_C PF08767.6 EON97781.1 - 0.0027 16.6 0.7 0.016 14.0 0.1 2.1 2 0 0 2 2 2 1 CRM1 C terminal Ipi1_N PF12333.3 EON97781.1 - 0.1 12.5 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF4243 PF14027.1 EON97782.1 - 9.1e-87 291.5 0.1 1.1e-86 291.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) zf-H2C2_2 PF13465.1 EON97783.1 - 2e-06 27.7 3.0 0.023 14.9 0.9 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.2 EON97783.1 - 5e-06 26.5 1.5 1.3e-05 25.2 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EON97783.1 - 5.6e-06 26.3 4.5 1.3e-05 25.2 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EON97783.1 - 3.9e-05 23.6 2.5 0.00011 22.2 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EON97783.1 - 5.8e-05 23.1 2.3 0.00013 22.0 1.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EON97783.1 - 0.0011 18.8 1.5 0.0026 17.5 1.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EON97783.1 - 0.0038 17.3 0.2 0.0066 16.5 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mito_fiss_reg PF05308.6 EON97783.1 - 0.11 11.8 2.3 0.19 11.0 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PAP2 PF01569.16 EON97783.1 - 0.26 10.9 2.9 0.21 11.2 0.4 1.8 1 1 0 2 2 2 0 PAP2 superfamily SprT-like PF10263.4 EON97783.1 - 0.55 9.8 3.1 1 9.0 0.5 2.0 1 1 0 2 2 2 0 SprT-like family Metallophos PF00149.23 EON97784.1 - 2.3e-07 30.3 1.1 5.3e-07 29.2 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BLVR PF06375.6 EON97784.1 - 0.098 12.4 20.9 0.71 9.6 0.7 3.4 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Ydc2-catalyt PF09159.5 EON97784.1 - 1.4 8.3 7.7 0.18 11.2 1.7 2.0 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Mt_ATP-synt_B PF05405.9 EON97785.1 - 1.8e-52 177.0 6.8 2.8e-52 176.4 4.7 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.12 EON97785.1 - 0.16 11.6 2.5 0.76 9.4 0.5 2.2 1 1 1 2 2 2 0 DAK2 domain zf-CCCH PF00642.19 EON97786.1 - 2.8e-06 26.8 29.1 0.003 17.1 0.0 6.1 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_60s PF00428.14 EON97786.1 - 2.2 8.7 6.1 1.3 9.4 2.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein NUFIP1 PF10453.4 EON97787.1 - 1.8e-11 43.3 0.0 7.7e-11 41.3 0.0 2.2 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EON97787.1 - 0.026 14.1 4.9 0.045 13.4 3.4 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.7 EON97788.1 - 1.6e-34 118.7 0.1 2.7e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EON97788.1 - 2e-14 53.4 0.0 3.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EON97788.1 - 0.008 16.2 0.3 0.06 13.4 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain THF_DHG_CYH PF00763.18 EON97789.1 - 7.9e-21 74.2 0.3 1.1e-20 73.7 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EON97789.1 - 3.6e-14 52.1 0.0 3.4e-09 35.9 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 EON97789.1 - 0.035 12.9 0.1 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_60s PF00428.14 EON97792.1 - 7.7e-28 96.7 11.0 9e-28 96.5 7.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rad17 PF03215.10 EON97793.1 - 1.5e-56 192.2 0.0 2.1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EON97793.1 - 0.019 14.5 0.1 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EON97793.1 - 0.022 14.9 0.1 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EON97793.1 - 0.022 14.5 0.1 0.061 13.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EON97793.1 - 0.032 14.3 0.1 0.1 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain FAM104 PF15434.1 EON97793.1 - 0.068 13.3 5.5 0.25 11.5 3.8 2.0 1 0 0 1 1 1 0 Family 104 RNA_helicase PF00910.17 EON97793.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Herpes_Helicase PF02689.9 EON97793.1 - 0.58 7.8 0.0 0.86 7.2 0.0 1.1 1 0 0 1 1 1 0 Helicase SPT2 PF08243.6 EON97795.1 - 9.5e-11 42.0 23.5 9.5e-11 42.0 16.3 2.7 3 1 0 3 3 3 1 SPT2 chromatin protein Menin PF05053.8 EON97795.1 - 2.8 6.0 6.8 3.5 5.6 4.7 1.1 1 0 0 1 1 1 0 Menin SDA1 PF05285.7 EON97796.1 - 5.7 6.1 12.2 9.1 5.4 8.4 1.2 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 EON97796.1 - 6.8 6.2 13.1 19 4.7 8.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin LSM PF01423.17 EON97797.1 - 2.3e-17 62.3 0.0 3.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EON97797.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HlyD_3 PF13437.1 EON97797.1 - 0.042 14.1 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF2763 PF10961.3 EON97797.1 - 0.071 13.5 3.5 0.12 12.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) MatE PF01554.13 EON97798.1 - 0.15 11.6 3.1 0.32 10.5 0.5 2.0 2 0 0 2 2 2 0 MatE DUF202 PF02656.10 EON97798.1 - 1.2 9.3 4.5 20 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TctB PF07331.6 EON97798.1 - 1.7 8.2 7.5 7.5 6.2 5.2 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family WD40 PF00400.27 EON97799.1 - 3.6e-59 194.6 23.2 4.8e-08 32.5 0.2 11.2 10 1 0 10 10 10 9 WD domain, G-beta repeat Pyr_redox_3 PF13738.1 EON97799.1 - 7.3e-21 75.1 0.0 3.1e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Utp12 PF04003.7 EON97799.1 - 4.1e-19 68.5 0.5 7.5e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family FMO-like PF00743.14 EON97799.1 - 1.5e-10 39.8 0.1 3.3e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EON97799.1 - 9.8e-08 31.2 0.0 4.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Nucleoporin_N PF08801.6 EON97799.1 - 0.0024 16.6 3.0 0.4 9.3 0.1 4.0 2 1 3 5 5 5 1 Nup133 N terminal like Nup160 PF11715.3 EON97799.1 - 0.0032 15.6 2.5 0.13 10.4 0.0 3.9 4 1 0 5 5 5 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EON97799.1 - 0.017 14.8 0.1 1.2 8.8 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A FGGY_C PF02782.11 EON97799.1 - 0.13 11.8 0.1 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain CAP59_mtransfer PF11735.3 EON97800.1 - 5.7e-79 264.7 0.0 7.8e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Vps26 PF03643.10 EON97801.1 - 1.3e-130 434.1 0.7 1.5e-130 433.9 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EON97801.1 - 6.1e-05 22.8 0.0 0.19 11.5 0.0 3.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ribosomal_S8e PF01201.17 EON97802.1 - 9.6e-35 119.6 5.2 7.4e-34 116.7 3.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e NOC3p PF07540.6 EON97803.1 - 1.1e-29 102.5 0.3 5.4e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EON97803.1 - 4.9e-29 100.8 0.0 2.1e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family PI3K_1B_p101 PF10486.4 EON97803.1 - 6.2 4.2 11.5 0.083 10.4 0.2 2.3 2 1 1 3 3 3 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BP28CT PF08146.7 EON97804.1 - 2.9e-42 143.9 3.2 3.4e-42 143.7 0.7 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EON97804.1 - 1.1e-24 86.7 3.8 1.1e-24 86.7 2.6 5.5 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EON97804.1 - 1.6e-07 30.8 8.3 0.014 15.3 0.0 6.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EON97804.1 - 1.7e-07 31.3 12.4 0.25 11.6 0.3 6.7 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EON97804.1 - 0.18 12.3 22.8 1.4 9.5 0.8 8.1 9 1 1 10 10 10 0 HEAT-like repeat UCH PF00443.24 EON97805.1 - 4.5e-37 127.6 2.4 8.6e-30 103.7 0.0 3.3 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EON97805.1 - 8.1e-22 77.2 0.1 8.6e-21 73.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EON97805.1 - 1e-11 44.8 6.6 7.1e-10 38.8 0.1 2.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PCP PF02429.10 EON97805.1 - 0.066 13.3 0.1 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein Pox_A3L PF05288.6 EON97805.1 - 0.55 9.9 4.2 0.45 10.2 0.2 2.9 3 0 0 3 3 3 0 Poxvirus A3L Protein Pyr_redox_2 PF07992.9 EON97806.1 - 1.2e-32 113.3 0.0 2.3e-32 112.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON97806.1 - 2.2e-14 53.6 0.0 1.5e-12 47.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON97806.1 - 3.9e-07 30.3 0.0 0.0044 17.0 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON97806.1 - 0.022 14.7 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Drf_FH1 PF06346.7 EON97806.1 - 0.031 13.7 0.7 0.077 12.5 0.5 1.5 1 0 0 1 1 1 0 Formin Homology Region 1 DAO PF01266.19 EON97806.1 - 0.055 12.3 0.0 2.7 6.7 0.0 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Dehydratase_hem PF13816.1 EON97808.1 - 1.9e-75 253.8 0.0 2.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Trep_Strep PF09605.5 EON97809.1 - 0.0038 16.9 0.1 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) ATG27 PF09451.5 EON97809.1 - 0.058 12.6 0.5 0.082 12.1 0.4 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF202 PF02656.10 EON97809.1 - 0.095 12.9 0.3 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Shisa PF13908.1 EON97809.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UPF0370 PF13980.1 EON97809.1 - 0.59 9.9 3.7 0.94 9.3 2.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF4381 PF14316.1 EON97809.1 - 1.2 9.2 3.6 1.1 9.4 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) TRI12 PF06609.8 EON97810.1 - 8.3e-46 156.3 23.3 1e-45 156.1 16.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON97810.1 - 7.8e-17 61.0 31.2 7.8e-17 61.0 21.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily hDGE_amylase PF14701.1 EON97811.1 - 1.3e-175 584.3 0.0 1.7e-175 583.9 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EON97811.1 - 3.7e-111 371.4 0.0 8.1e-111 370.2 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EON97811.1 - 7.2e-91 303.9 0.0 1.3e-90 303.0 0.0 1.5 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EON97811.1 - 9.9e-25 86.2 0.4 2.3e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EON97811.1 - 0.002 17.5 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF2379 PF09543.5 EON97811.1 - 0.15 11.9 0.1 0.39 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Ribosomal_L5_C PF00673.16 EON97812.1 - 5e-22 77.4 0.0 7e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EON97812.1 - 2.6e-21 75.1 0.1 7e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Sugar_tr PF00083.19 EON97813.1 - 5.3e-131 437.3 25.3 6.1e-131 437.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97813.1 - 4.7e-18 65.0 38.8 2.8e-15 55.9 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSase_L_D2 PF02786.12 EON97814.1 - 5.8e-82 274.0 0.5 9.3e-82 273.4 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EON97814.1 - 3e-66 222.5 0.0 5.3e-66 221.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.14 EON97814.1 - 8.4e-27 94.3 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EON97814.1 - 2.7e-20 72.8 0.3 6.8e-20 71.5 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_chain PF00289.17 EON97814.1 - 6.5e-19 68.0 0.0 1.5e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EON97814.1 - 8.1e-19 67.0 3.2 9.9e-19 66.7 1.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EON97814.1 - 9.5e-15 54.1 0.0 4.1e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_carb_C PF02785.14 EON97814.1 - 3.4e-12 46.2 0.0 9.1e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.8 EON97814.1 - 3.7e-12 46.0 0.0 7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EON97814.1 - 2.1e-10 40.1 1.1 2.7e-07 30.1 0.0 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EON97814.1 - 2.4e-08 33.5 0.1 5.1e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EON97814.1 - 1.3e-07 31.3 0.1 3.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EON97814.1 - 5.2e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EON97814.1 - 0.00019 20.8 0.0 0.0031 16.8 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 EON97814.1 - 0.00021 20.5 0.0 0.044 12.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 EON97814.1 - 0.001 18.6 0.0 0.0054 16.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 EON97814.1 - 0.0012 19.1 0.0 0.92 9.8 0.0 3.4 3 0 0 3 3 3 1 HlyD family secretion protein DUF2118 PF09891.4 EON97814.1 - 0.033 13.8 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.6 EON97814.1 - 0.06 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PYNP_C PF07831.8 EON97814.1 - 0.078 12.4 0.8 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 EON97814.1 - 0.11 12.1 0.5 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein MFS_1 PF07690.11 EON97815.1 - 7e-41 140.1 52.7 7e-41 140.1 36.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON97815.1 - 5.5e-18 64.4 16.6 9.2e-18 63.7 11.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EON97815.1 - 3.2e-11 42.4 34.6 4.9e-08 31.9 22.5 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1914 PF08932.5 EON97815.1 - 0.0048 16.9 0.2 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1914) DUF2530 PF10745.4 EON97815.1 - 0.082 12.8 14.2 0.12 12.3 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) MPC PF03650.8 EON97816.1 - 1.6e-34 118.3 0.0 2.6e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EON97816.1 - 1.2e-17 63.1 0.0 2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain AIG2_2 PF13772.1 EON97817.1 - 7.5e-07 29.1 0.0 4.7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family FAD_binding_3 PF01494.14 EON97818.1 - 1.7e-09 37.2 0.5 0.038 13.0 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EON97818.1 - 0.00048 20.0 0.3 0.0011 18.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EON97818.1 - 0.00075 19.3 0.2 0.0017 18.1 0.1 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EON97818.1 - 0.0011 17.9 0.6 0.0024 16.8 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON97818.1 - 0.015 15.1 0.2 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON97818.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON97818.1 - 0.057 13.8 0.4 0.13 12.7 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON97818.1 - 0.081 11.3 0.3 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EON97818.1 - 0.19 10.7 0.0 0.42 9.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EON97818.1 - 0.22 11.2 0.4 0.43 10.2 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_N PF01210.18 EON97819.1 - 7.9e-45 152.3 0.0 3.1e-44 150.4 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EON97819.1 - 6e-43 146.1 0.9 8.8e-43 145.5 0.7 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K_oxygenase PF13434.1 EON97819.1 - 0.051 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4440 PF14534.1 EON97820.1 - 8e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EON97820.1 - 0.0026 18.1 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EON97820.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Secretin_N_2 PF07655.8 EON97820.1 - 0.021 15.2 0.6 0.035 14.4 0.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain RHD PF00554.17 EON97820.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Rel homology domain (RHD) MobB PF03205.9 EON97820.1 - 0.031 13.9 0.1 0.13 12.0 0.0 2.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AA_permease_2 PF13520.1 EON97821.1 - 1.1e-61 208.6 19.2 1.4e-61 208.3 13.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON97821.1 - 1.2e-13 50.3 13.3 1.3e-13 50.1 9.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4064 PF13273.1 EON97821.1 - 0.016 15.2 6.1 0.34 11.0 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) adh_short PF00106.20 EON97822.1 - 7.5e-06 25.9 0.6 0.00051 19.9 0.0 2.5 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EON97822.1 - 0.0011 18.9 0.1 0.0031 17.5 0.1 1.7 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EON97822.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EON97822.1 - 0.032 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family FAD_binding_3 PF01494.14 EON97822.1 - 0.034 13.1 0.3 0.052 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.16 EON97822.1 - 0.057 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EON97822.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ABC_tran PF00005.22 EON97823.1 - 3e-37 127.9 0.0 1e-25 90.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EON97823.1 - 4.4e-19 68.9 12.9 6.8e-19 68.3 8.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EON97823.1 - 1.6e-12 47.1 0.5 1.6e-05 24.2 0.0 3.1 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EON97823.1 - 6.8e-06 26.2 0.0 0.3 11.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EON97823.1 - 0.0011 18.4 1.4 0.0025 17.3 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EON97823.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON97823.1 - 0.0015 18.5 1.0 0.024 14.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EON97823.1 - 0.0032 17.3 0.0 1.4 8.8 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EON97823.1 - 0.0055 15.6 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EON97823.1 - 0.0059 16.0 0.6 7.6 5.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EON97823.1 - 0.016 14.8 0.2 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EON97823.1 - 0.023 13.8 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EON97823.1 - 0.026 14.6 0.4 0.19 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EON97823.1 - 0.028 13.5 0.2 0.072 12.1 0.0 1.7 2 0 0 2 2 1 0 KaiC AAA_10 PF12846.2 EON97823.1 - 0.046 13.1 0.1 0.28 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA-like domain AAA_17 PF13207.1 EON97823.1 - 0.049 14.4 0.0 0.16 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EON97823.1 - 0.06 13.1 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 IIGP PF05049.8 EON97823.1 - 0.07 11.9 1.2 0.69 8.6 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EON97823.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EON97823.1 - 0.14 11.0 0.1 0.27 10.1 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EON97823.1 - 0.23 11.7 0.5 0.83 9.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EON97823.1 - 0.47 8.8 0.0 0.47 8.8 0.0 1.9 3 0 0 3 3 3 0 AAA domain SGL PF08450.7 EON97825.1 - 5.3e-07 29.2 0.3 8e-07 28.6 0.1 1.4 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Glyco_transf_54 PF04666.8 EON97826.1 - 8.1e-07 28.0 0.0 1.9e-05 23.5 0.0 2.6 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region YjgP_YjgQ PF03739.9 EON97826.1 - 0.2 10.3 0.8 0.31 9.7 0.6 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family MatE PF01554.13 EON97827.1 - 2e-31 108.8 5.0 3.1e-31 108.1 3.5 1.2 1 0 0 1 1 1 1 MatE GPI-anchored PF10342.4 EON97828.1 - 9.9e-18 64.4 3.9 9.9e-18 64.4 2.7 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TRI12 PF06609.8 EON97829.1 - 7.5e-52 176.3 22.3 9.5e-52 175.9 15.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON97829.1 - 6.3e-26 90.9 52.6 3.9e-25 88.3 36.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97829.1 - 3.2e-09 35.8 7.5 3.2e-09 35.8 5.2 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter SDA1 PF05285.7 EON97830.1 - 1.4e-86 290.7 31.9 1.4e-86 290.7 22.1 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EON97830.1 - 2.2e-23 82.3 0.0 6.7e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain DUF2277 PF10041.4 EON97830.1 - 0.011 15.6 0.6 0.38 10.7 0.1 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Mito_carr PF00153.22 EON97830.1 - 0.063 12.9 2.2 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial carrier protein DIOX_N PF14226.1 EON97831.1 - 9.7e-23 80.9 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.13 EON97832.1 - 4e-12 45.5 0.0 6.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fringe PF02434.11 EON97833.1 - 3.4e-05 23.2 2.5 0.00036 19.8 1.7 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EON97833.1 - 0.046 13.3 0.1 0.19 11.2 0.1 2.1 1 1 0 1 1 1 0 Galactosyltransferase Arginase PF00491.16 EON97834.1 - 8.4e-74 248.3 0.0 1.1e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EON97834.1 - 0.09 12.9 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain KR PF08659.5 EON97835.1 - 3.9e-40 137.4 0.4 7.3e-40 136.5 0.2 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EON97835.1 - 2.7e-28 98.9 0.3 4.4e-28 98.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EON97835.1 - 3.3e-08 33.6 0.3 7.5e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3867 PF12983.2 EON97835.1 - 0.094 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DUF3446 PF11928.3 EON97835.1 - 1 9.5 4.1 0.95 9.7 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) GMC_oxred_N PF00732.14 EON97836.1 - 1.8e-27 96.3 0.1 2.5e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON97836.1 - 3e-23 82.7 0.0 5.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON97836.1 - 0.00015 20.7 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON97836.1 - 0.025 13.4 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_S7e PF01251.13 EON97837.1 - 9.2e-82 273.1 0.3 1e-81 272.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PX PF00787.19 EON97838.1 - 5e-15 55.2 0.0 8.1e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EON97838.1 - 6.1e-12 45.0 6.0 1.1e-11 44.1 4.2 1.4 1 0 0 1 1 1 1 SNARE domain adh_short PF00106.20 EON97839.1 - 8.5e-22 77.8 0.1 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97839.1 - 1.9e-05 24.4 0.1 0.0001 22.0 0.1 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON97839.1 - 4.5e-05 23.3 0.1 0.0001 22.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EON97839.1 - 0.003 17.5 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EON97839.1 - 0.05 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EON97839.1 - 0.12 11.3 0.2 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase LIP PF03583.9 EON97840.1 - 8.7e-61 205.6 0.2 3.1e-60 203.8 0.1 1.7 1 1 0 1 1 1 1 Secretory lipase GLE1 PF07817.8 EON97840.1 - 0.055 12.3 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein Macoilin PF09726.4 EON97841.1 - 3.9 5.6 6.1 4.9 5.3 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Flavin_Reduct PF01613.13 EON97842.1 - 1e-16 61.1 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain MFS_1 PF07690.11 EON97843.1 - 3e-30 105.1 19.4 1.7e-16 59.8 8.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily YjgP_YjgQ PF03739.9 EON97843.1 - 0.0035 16.1 0.6 0.0035 16.1 0.4 2.3 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family DUF1049 PF06305.6 EON97843.1 - 0.075 12.5 4.6 0.72 9.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) AMP-binding PF00501.23 EON97844.1 - 2.1e-60 204.3 0.2 2e-31 108.8 0.0 4.9 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EON97844.1 - 9.2e-12 45.5 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EON97844.1 - 0.0018 18.0 1.0 0.0049 16.6 0.7 1.7 1 0 0 1 1 1 1 Gas vesicle protein G DEAD PF00270.24 EON97845.1 - 1.3e-44 151.6 0.1 6.1e-44 149.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON97845.1 - 5.1e-25 87.1 0.0 1.2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EON97845.1 - 4.8e-05 21.9 0.7 0.00035 19.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EON97845.1 - 0.041 13.6 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EON97845.1 - 0.18 11.6 2.8 0.39 10.5 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4407 PF14362.1 EON97845.1 - 5 5.9 8.8 15 4.4 6.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Iso_dh PF00180.15 EON97846.1 - 7e-87 291.5 0.0 8.6e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 EON97847.1 - 2.9e-10 39.4 29.3 2.9e-10 39.4 20.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON97847.1 - 1.7e-07 30.8 4.6 2.1e-07 30.5 2.0 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EON97847.1 - 2.4e-07 29.7 10.0 2.4e-07 29.7 6.9 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter Methyltransf_2 PF00891.13 EON97848.1 - 9.3e-34 116.6 0.0 1.5e-33 115.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EON97848.1 - 0.00018 21.2 0.0 0.00045 19.9 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain HTH_Crp_2 PF13545.1 EON97848.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain tRNA-synt_2 PF00152.15 EON97849.1 - 2.6e-74 249.9 0.1 2.6e-74 249.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EON97849.1 - 5.5e-16 58.2 0.1 8.2e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EON97849.1 - 5e-06 26.2 0.0 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SR-25 PF10500.4 EON97849.1 - 0.062 12.7 11.0 0.1 12.0 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 EON97849.1 - 4.5 6.8 8.2 9.8 5.7 5.7 1.6 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PDEase_II PF02112.10 EON97850.1 - 1.4e-06 27.4 0.0 1.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II YihI PF04220.7 EON97850.1 - 2.7 7.2 5.5 0.21 10.9 0.6 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) EBP PF05241.7 EON97851.1 - 7.8e-05 21.7 6.1 0.00013 21.0 4.2 1.4 1 1 0 1 1 1 1 Emopamil binding protein EB1 PF03271.12 EON97852.1 - 2.4e-18 65.8 1.1 4.7e-18 64.9 0.8 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EON97852.1 - 1.3e-07 31.6 0.8 2e-07 30.9 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Annexin PF00191.15 EON97853.1 - 1.7e-49 165.5 5.8 2.2e-13 49.9 0.1 4.3 4 0 0 4 4 4 4 Annexin Apo-CII PF05355.6 EON97853.1 - 0.073 12.9 1.4 0.29 11.0 0.2 2.4 1 1 0 2 2 2 0 Apolipoprotein C-II SicP-binding PF09119.5 EON97853.1 - 0.11 12.2 0.1 12 5.7 0.0 3.6 2 2 2 4 4 4 0 SicP binding Spore_III_AF PF09581.5 EON97853.1 - 0.17 11.7 0.8 4.2 7.1 0.2 2.5 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Sugar_tr PF00083.19 EON97854.1 - 1.8e-67 227.9 15.7 7.2e-49 166.5 1.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON97854.1 - 4.1e-16 58.6 17.0 5.4e-10 38.5 3.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_3 PF13469.1 EON97855.1 - 0.081 13.8 0.0 0.082 13.8 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family ATP-grasp_3 PF02655.9 EON97856.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EON97856.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain p450 PF00067.17 EON97858.1 - 5.9e-10 38.2 0.0 7.8e-10 37.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EON97859.1 - 3.2e-23 82.6 0.1 5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON97859.1 - 2.3e-06 27.4 1.3 0.029 14.1 0.2 2.6 1 1 1 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EON97859.1 - 1.9e-05 23.7 1.8 0.002 17.0 0.1 3.0 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EON97859.1 - 4.6e-05 22.0 0.0 0.015 13.7 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 EON97859.1 - 7.8e-05 21.7 0.1 0.00021 20.2 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON97859.1 - 0.00016 21.6 0.6 0.00041 20.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON97859.1 - 0.0011 19.1 0.1 0.082 12.9 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON97859.1 - 0.0029 16.7 0.8 0.0072 15.4 0.3 1.8 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EON97859.1 - 0.004 16.1 0.0 0.0064 15.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EON97859.1 - 0.0063 15.4 1.5 0.19 10.5 0.2 2.9 2 1 1 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EON97859.1 - 0.027 13.5 0.2 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 EON97859.1 - 0.029 13.3 0.0 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EON97859.1 - 0.18 12.2 0.5 1.8 9.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4131 PF13567.1 EON97860.1 - 0.052 12.9 0.0 0.067 12.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Sex_peptide PF08138.6 EON97860.1 - 0.11 12.3 0.2 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Sex peptide (SP) family Cytochrom_B_C PF00032.12 EON97860.1 - 0.12 12.6 1.2 9.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD p450 PF00067.17 EON97862.1 - 1.1e-39 136.2 0.0 1.2e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1311 PF07007.7 EON97862.1 - 0.74 9.9 3.8 1.7 8.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1311) Glyco_hydro_2_C PF02836.12 EON97863.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DIOX_N PF14226.1 EON97866.1 - 1.5e-16 61.0 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EON97866.1 - 4.3e-14 52.6 0.0 1.1e-13 51.3 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4040 PF13244.1 EON97867.1 - 0.15 12.0 0.6 0.15 12.0 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) adh_short PF00106.20 EON97868.1 - 4.9e-07 29.8 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97868.1 - 0.0032 17.2 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON97868.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 KR domain AA_permease PF00324.16 EON97870.1 - 9e-65 218.8 36.5 3.5e-43 147.6 11.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EON97870.1 - 5e-14 51.6 13.6 5e-14 51.6 9.4 2.1 1 1 1 2 2 2 2 Amino acid permease DUF2101 PF09874.4 EON97870.1 - 0.12 11.8 2.8 0.18 11.2 1.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) MFS_1 PF07690.11 EON97871.1 - 6.6e-30 104.0 57.7 1.5e-23 83.1 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP2_3 PF14378.1 EON97873.1 - 1.4e-23 83.4 10.4 6.7e-18 64.8 3.2 2.9 2 1 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.16 EON97873.1 - 0.018 14.6 5.9 0.05 13.2 3.7 2.0 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.1 EON97873.1 - 0.084 13.1 3.6 0.071 13.3 0.5 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Alpha-amylase PF00128.19 EON97874.1 - 2.4e-29 102.7 0.1 3.3e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EON97874.1 - 2.4e-09 37.2 0.1 6.9e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Yeast-kill-tox PF09207.6 EON97874.1 - 2.4 8.6 6.6 0.61 10.5 0.7 2.8 2 1 0 2 2 2 0 Yeast killer toxin Aldo_ket_red PF00248.16 EON97875.1 - 1.7e-43 148.4 0.0 2.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_31 PF01055.21 EON97876.1 - 5.1e-92 308.9 7.9 2.5e-91 306.7 5.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EON97876.1 - 5.1e-07 29.4 1.1 1.9e-06 27.6 0.8 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Dynactin_p62 PF05502.8 EON97877.1 - 4.9e-184 612.6 0.0 6e-184 612.3 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF1996 PF09362.5 EON97878.1 - 7.6e-18 65.0 1.0 9.6e-18 64.7 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBS PF00571.23 EON97879.1 - 0.002 17.8 0.0 0.22 11.3 0.0 2.6 2 1 1 3 3 3 1 CBS domain Spindle_Spc25 PF08234.7 EON97879.1 - 0.04 13.9 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 DUF4350 PF14258.1 EON97879.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) AphA_like PF14557.1 EON97879.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator G6PD_C PF02781.11 EON97881.1 - 5.9e-134 445.5 0.0 8e-134 445.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EON97881.1 - 7e-64 215.4 0.1 1.1e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 EON97881.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Cyclin_N PF00134.18 EON97882.1 - 5.6e-44 148.7 0.1 2.8e-43 146.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EON97882.1 - 4.4e-34 116.9 0.0 8.6e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DEAD PF00270.24 EON97883.1 - 2.8e-20 72.5 0.2 1.4e-19 70.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON97883.1 - 3.1e-20 71.8 0.1 8.3e-17 60.8 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.5 EON97883.1 - 2e-09 37.0 0.1 3.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EON97883.1 - 9.3e-06 25.2 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.18 EON97883.1 - 0.00072 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EON97883.1 - 0.0027 17.5 0.0 0.012 15.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PAP2 PF01569.16 EON97884.1 - 5e-21 74.7 5.5 7.7e-21 74.1 2.2 2.4 2 1 0 2 2 2 1 PAP2 superfamily SseC PF04888.7 EON97884.1 - 0.71 9.1 2.4 1.2 8.3 1.7 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Rhomboid PF01694.17 EON97884.1 - 4.6 7.2 10.9 5.7 6.9 0.4 3.1 3 1 0 3 3 3 0 Rhomboid family Mad3_BUB1_I PF08311.7 EON97885.1 - 2.3e-43 146.9 0.5 4e-43 146.1 0.4 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EON97885.1 - 3.1e-12 46.1 0.0 7.4e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97885.1 - 0.00052 19.1 0.0 0.0024 16.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EON97886.1 - 3.2e-23 82.0 49.8 3e-22 78.8 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EON97886.1 - 0.59 10.5 0.0 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) tRNA-synt_1 PF00133.17 EON97887.1 - 1.1e-216 720.5 0.5 5.3e-216 718.2 0.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EON97887.1 - 4.6e-30 104.3 0.1 1.2e-29 103.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EON97887.1 - 1e-18 67.2 0.3 5.3e-07 28.6 0.0 4.5 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EON97887.1 - 9.6e-13 47.8 7.5 8.3e-11 41.5 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EON97887.1 - 0.0049 16.9 2.7 0.0049 16.9 1.9 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 EON97887.1 - 0.022 13.8 0.0 0.54 9.3 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Thioredoxin PF00085.15 EON97889.1 - 1.3e-63 211.1 8.3 2.5e-32 110.6 0.2 3.8 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 EON97889.1 - 1.2e-55 188.2 3.1 7.9e-40 136.6 0.7 3.4 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EON97889.1 - 1.3e-12 47.9 6.3 6.7e-05 23.0 0.2 4.9 2 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EON97889.1 - 2.8e-12 46.5 0.2 0.00021 21.3 0.0 4.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EON97889.1 - 1.3e-11 44.3 0.6 4.2e-05 23.4 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EON97889.1 - 6.2e-09 35.5 2.2 0.0047 16.5 0.1 3.6 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EON97889.1 - 1e-08 34.8 4.1 0.0014 18.1 0.0 3.5 3 0 0 3 3 3 3 Redoxin Calsequestrin PF01216.12 EON97889.1 - 6.5e-08 31.7 1.2 6.5e-08 31.7 0.8 1.8 2 1 0 2 2 2 1 Calsequestrin ERp29_N PF07912.8 EON97889.1 - 6.5e-05 22.8 0.8 0.98 9.3 0.0 4.0 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EON97889.1 - 0.00035 20.6 4.2 0.25 11.3 0.2 3.9 3 3 0 3 3 3 2 Thioredoxin DSBA PF01323.15 EON97889.1 - 0.021 14.3 0.2 8.6 5.8 0.0 3.7 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EON97889.1 - 0.022 14.5 1.9 0.067 13.0 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EON97889.1 - 0.067 12.7 0.1 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin SHD1 PF03983.7 EON97890.1 - 4.4e-38 128.7 0.1 8.1e-38 127.9 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EON97890.1 - 3.8e-36 122.2 10.0 4.2e-13 48.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EON97890.1 - 5.6e-35 118.6 10.4 3e-12 45.8 0.3 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EON97890.1 - 3.1e-26 90.6 0.1 4e-08 32.6 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EON97890.1 - 1.8e-08 34.4 1.9 0.017 15.2 0.1 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain UQ_con PF00179.21 EON97891.1 - 6.6e-25 87.1 0.0 7.7e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EON97891.1 - 3.7e-07 29.9 0.0 5.2e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EON97891.1 - 0.0041 16.7 0.1 0.0053 16.4 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EON97891.1 - 0.0045 16.8 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain F-box-like PF12937.2 EON97893.1 - 0.0002 21.0 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L2_C PF03947.13 EON97894.1 - 2.9e-42 143.5 0.8 1.7e-41 141.0 0.6 2.2 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EON97894.1 - 4.6e-27 93.7 0.3 9.1e-27 92.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HTH_17 PF12728.2 EON97894.1 - 0.051 13.8 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ATP-synt PF00231.14 EON97895.1 - 2.6e-72 243.6 5.8 3e-72 243.4 4.0 1.0 1 0 0 1 1 1 1 ATP synthase Rotamase_3 PF13616.1 EON97895.1 - 0.049 13.8 0.3 1.3 9.2 0.0 2.4 1 1 0 2 2 2 0 PPIC-type PPIASE domain NT5C PF06941.7 EON97895.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) BioT2 PF15368.1 EON97895.1 - 0.09 12.5 0.3 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 Spermatogenesis family BioT2 COesterase PF00135.23 EON97896.1 - 5.7e-52 177.1 0.0 7.4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EON97896.1 - 1.5e-07 31.2 0.0 5.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON97896.1 - 0.00058 19.1 0.1 0.0009 18.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EON97896.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M1 PF01433.15 EON97897.1 - 1e-142 475.8 0.0 1.3e-142 475.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EON97897.1 - 2.8e-95 319.2 0.0 8.8e-95 317.6 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EON97897.1 - 2.3e-20 72.9 0.2 4.9e-20 71.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily FAA_hydrolase PF01557.13 EON97898.1 - 1.5e-50 171.6 0.0 1.9e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Prefoldin_2 PF01920.15 EON97899.1 - 4.5e-22 77.8 0.5 5.5e-22 77.5 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin PF00804.20 EON97899.1 - 0.0029 17.7 5.0 0.018 15.2 0.1 2.1 1 1 1 2 2 2 1 Syntaxin DUF641 PF04859.7 EON97899.1 - 0.012 15.3 2.6 1.8 8.3 0.4 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TBPIP PF07106.8 EON97899.1 - 0.12 11.8 3.9 2.2 7.8 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliJ PF02050.11 EON97899.1 - 0.31 11.1 6.5 1.1 9.3 2.3 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein Fib_alpha PF08702.5 EON97899.1 - 0.41 10.7 4.7 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 EON97899.1 - 2.1 8.3 10.2 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1932 PF09130.6 EON97900.1 - 7.4e-19 67.2 0.2 1.6e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EON97900.1 - 7.6e-09 35.6 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EON97900.1 - 2.1e-08 34.5 0.2 6.3e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EON97900.1 - 0.0009 18.4 0.1 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EON97900.1 - 0.012 15.2 0.5 0.026 14.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3-HAO PF06052.7 EON97901.1 - 1.6e-64 215.9 0.0 1.8e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EON97901.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EON97901.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.6 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 EON97901.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.2 EON97901.1 - 0.0037 17.0 2.7 0.0072 16.1 1.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EON97901.1 - 0.058 12.6 0.8 6.2 6.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 EON97901.1 - 0.085 12.5 2.3 0.8 9.4 0.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.19 EON97901.1 - 5.9 6.8 6.5 3.1 7.7 0.3 2.6 2 1 0 2 2 2 0 B-box zinc finger BAH PF01426.13 EON97902.1 - 6.4e-06 25.9 0.1 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EON97902.1 - 0.00071 19.2 2.4 0.0017 18.0 1.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EON97902.1 - 0.002 18.0 0.6 0.0045 16.9 0.4 1.6 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H PF13771.1 EON97902.1 - 0.067 13.3 0.8 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EON97902.1 - 0.12 12.3 1.6 0.28 11.1 1.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Topoisom_I_N PF02919.10 EON97903.1 - 8.9e-97 322.5 3.8 8.9e-97 322.5 2.6 2.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EON97903.1 - 1e-84 283.3 6.4 1e-84 283.3 4.4 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EON97903.1 - 1.3e-29 101.6 0.3 4.2e-29 100.0 0.2 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain adh_short PF00106.20 EON97904.1 - 2.6e-27 95.7 1.5 3.7e-27 95.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON97904.1 - 6.7e-20 71.8 0.3 7.5e-20 71.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON97904.1 - 2.4e-12 46.8 1.3 3.4e-12 46.4 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON97904.1 - 8.4e-05 22.1 0.7 0.00017 21.0 0.3 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RhaA PF06134.6 EON97904.1 - 0.013 14.4 0.0 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 L-rhamnose isomerase (RhaA) DUF507 PF04368.8 EON97904.1 - 0.075 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF507) SNARE_assoc PF09335.6 EON97905.1 - 8.6e-17 61.4 11.8 1.6e-16 60.6 3.4 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1049 PF06305.6 EON97905.1 - 2.8 7.4 0.0 2.8 7.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) HAMP PF00672.20 EON97905.1 - 7.8 6.7 0.0 7.8 6.7 0.0 3.0 3 0 0 3 3 3 0 HAMP domain A_deaminase PF00962.17 EON97906.1 - 4.6e-113 377.4 0.2 6.3e-113 377.0 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 EON97906.1 - 2.7e-66 223.5 8.7 1.1e-44 152.5 1.9 2.2 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.15 EON97906.1 - 0.21 11.6 14.6 1.4 8.9 4.5 2.6 2 0 0 2 2 2 0 EamA-like transporter family TPT PF03151.11 EON97906.1 - 0.27 10.8 6.6 0.6 9.7 4.6 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family Mito_carr PF00153.22 EON97907.1 - 4e-51 170.7 1.6 1e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GerPB PF10803.3 EON97907.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Spore germination GerPB Abhydrolase_6 PF12697.2 EON97908.1 - 6.4e-23 81.8 8.4 1.1e-22 81.1 5.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97908.1 - 9.7e-13 48.0 0.6 5.1e-12 45.7 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97908.1 - 8.9e-08 31.9 0.1 2.2e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON97908.1 - 2.4e-06 27.2 0.1 4.7e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EON97908.1 - 0.019 14.3 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Putative esterase DLH PF01738.13 EON97908.1 - 0.15 11.3 0.2 0.9 8.7 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family Pkinase PF00069.20 EON97909.1 - 3.1e-71 239.5 0.0 4.2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON97909.1 - 9.2e-34 116.6 0.1 1.7e-33 115.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EON97909.1 - 5.1e-05 22.3 0.0 7.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EON97909.1 - 0.0058 15.9 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EON97909.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_1_2 PF00155.16 EON97910.1 - 2.8e-18 66.0 0.0 3.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EON97910.1 - 1.9e-05 23.4 0.0 3.5e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EON97910.1 - 0.01 14.9 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family UbiA PF01040.13 EON97911.1 - 0.0035 16.6 0.5 0.0068 15.6 0.4 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF202 PF02656.10 EON97911.1 - 0.017 15.3 5.8 0.017 15.3 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Yos1 PF08571.5 EON97912.1 - 1.1e-18 67.0 0.0 1.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Sec1 PF00995.18 EON97913.1 - 6.7e-137 457.4 0.0 7.7e-137 457.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PP2C PF00481.16 EON97914.1 - 8.5e-56 189.1 0.0 1.4e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EON97914.1 - 5.1e-44 147.2 51.0 2.3e-08 33.4 0.3 11.2 6 3 5 11 11 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EON97914.1 - 1.9e-40 136.4 70.0 2.1e-10 40.1 0.4 9.2 2 2 8 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 EON97914.1 - 8.9e-27 93.6 0.0 2.7e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EON97914.1 - 3e-21 72.1 49.1 0.16 12.0 0.0 17.4 17 1 0 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 EON97914.1 - 1.5e-13 48.5 44.4 0.28 11.5 0.1 15.7 17 0 0 17 17 17 4 Leucine rich repeat RA PF00788.18 EON97914.1 - 1.1e-11 45.0 0.0 5.5e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EON97914.1 - 4.7e-07 29.2 34.5 3.5 7.9 0.0 13.3 11 2 2 13 13 13 3 Leucine Rich repeat Sod_Cu PF00080.15 EON97915.1 - 7.6e-12 45.5 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) EXS PF03124.9 EON97916.1 - 1.1e-101 340.3 11.3 1.2e-101 340.1 7.8 1.0 1 0 0 1 1 1 1 EXS family ADC PF06314.6 EON97917.1 - 7.7e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.14 EON97917.1 - 4.4e-14 52.3 0.0 6.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Chorion_S16 PF05836.7 EON97917.1 - 0.016 15.1 0.1 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Chorion protein S16 AP_endonuc_2 PF01261.19 EON97918.1 - 1e-32 113.1 0.2 1.5e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GPI-anchored PF10342.4 EON97919.1 - 1.2e-21 76.9 0.3 1.2e-21 76.9 0.2 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EON97919.1 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CorA PF01544.13 EON97921.1 - 1.4e-14 53.8 2.5 3.6e-14 52.4 1.4 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Pox_A_type_inc PF04508.7 EON97921.1 - 0.078 12.8 0.5 0.078 12.8 0.4 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat p450 PF00067.17 EON97922.1 - 1.3e-55 188.7 0.0 4.2e-46 157.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF1771 PF08590.5 EON97924.1 - 1e-13 51.0 10.0 1e-13 51.0 6.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EON97924.1 - 1.5e-10 41.1 0.0 4.6e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Smr domain HBS1_N PF08938.5 EON97924.1 - 0.007 16.4 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 HBS1 N-terminus TRAM_LAG1_CLN8 PF03798.11 EON97925.1 - 2e-47 161.3 15.5 2e-47 161.3 10.7 1.5 2 0 0 2 2 2 1 TLC domain Glyco_hydro_10 PF00331.15 EON97926.1 - 5.7e-106 354.1 0.2 6.5e-106 353.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EON97926.1 - 0.016 15.6 0.0 0.071 13.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF2913 PF11140.3 EON97926.1 - 0.031 13.5 0.2 0.084 12.1 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2913) DUF4339 PF14237.1 EON97926.1 - 0.042 13.4 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) RTP PF02334.11 EON97926.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Replication terminator protein bZIP_1 PF00170.16 EON97927.1 - 0.052 13.5 7.7 0.22 11.4 5.4 1.9 1 1 0 1 1 1 0 bZIP transcription factor zf-HIT PF04438.11 EON97928.1 - 6.3e-10 38.5 4.6 9.2e-10 37.9 3.2 1.3 1 0 0 1 1 1 1 HIT zinc finger Epimerase PF01370.16 EON97929.1 - 1.6e-18 66.9 0.0 2.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EON97929.1 - 3.9e-09 35.8 0.0 5.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EON97929.1 - 6.9e-06 26.0 0.0 2.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EON97929.1 - 0.0006 19.8 0.4 0.0038 17.2 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EON97929.1 - 0.0024 16.6 0.0 0.02 13.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EON97929.1 - 0.0028 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EON97929.1 - 0.0054 15.6 0.0 0.0098 14.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 EON97929.1 - 0.031 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.13 EON97929.1 - 0.1 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NUDIX PF00293.23 EON97930.1 - 1.8e-13 50.2 0.0 3.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain SelB-wing_3 PF09107.6 EON97930.1 - 0.1 12.0 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Med14 PF08638.6 EON97931.1 - 9.3e-72 240.3 0.1 1.8e-71 239.4 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Protoglobin PF11563.3 EON97931.1 - 0.038 13.6 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Protoglobin Glyco_hydro_20 PF00728.17 EON97932.1 - 7.8e-85 285.1 0.0 9.5e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EON97932.1 - 5e-18 65.9 0.0 9.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EON97932.1 - 0.0099 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 UCH PF00443.24 EON97934.1 - 2.3e-61 207.2 0.0 5.4e-61 206.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EON97934.1 - 3.7e-30 105.3 0.1 1e-22 80.9 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EON97934.1 - 0.018 14.3 1.8 0.9 8.7 0.4 2.8 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PAT1 PF09770.4 EON97934.1 - 5.5 5.1 21.1 1.6 6.9 4.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 WSC PF01822.14 EON97935.1 - 4.7e-89 292.4 95.2 1.1e-19 70.1 10.4 6.0 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.6 EON97935.1 - 1.7e-30 105.9 0.0 4.4e-29 101.2 0.0 2.9 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EON97935.1 - 5.2e-20 71.3 3.5 5.7e-20 71.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1929) Macro_2 PF14519.1 EON97935.1 - 0.036 13.1 0.1 0.092 11.8 0.1 1.6 1 0 0 1 1 1 0 Macro-like domain DUF3359 PF11839.3 EON97936.1 - 2.8 8.3 6.5 0.45 10.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) DUF937 PF06078.6 EON97936.1 - 6.4 7.0 29.8 11 6.2 10.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) RRM_1 PF00076.17 EON97938.1 - 4.9e-18 64.5 0.0 7.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON97938.1 - 2.7e-13 49.6 0.0 4.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON97938.1 - 3.2e-08 33.2 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EON97938.1 - 3.9e-06 27.2 12.5 3.9e-06 27.2 8.6 4.6 3 1 2 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 Methyltransf_15 PF09445.5 EON97939.1 - 9.6e-46 155.3 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EON97939.1 - 1.9e-05 25.2 0.0 2.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON97939.1 - 2.8e-05 24.1 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EON97939.1 - 3.2e-05 23.5 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EON97939.1 - 0.00027 20.5 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EON97939.1 - 0.00046 19.6 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 EON97939.1 - 0.0016 17.2 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 EON97939.1 - 0.0072 15.7 0.1 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EON97939.1 - 0.06 12.3 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EON97939.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CK_II_beta PF01214.13 EON97940.1 - 4.8e-72 241.3 0.1 8.5e-72 240.5 0.1 1.4 1 0 0 1 1 1 1 Casein kinase II regulatory subunit GST_N_3 PF13417.1 EON97940.1 - 4.4e-23 81.2 0.0 9.4e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EON97940.1 - 6.7e-16 58.0 0.0 1.5e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EON97940.1 - 7.8e-06 25.9 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EON97940.1 - 0.0001 22.1 0.1 0.00038 20.3 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EON97940.1 - 0.009 15.9 0.3 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Acetyltransf_1 PF00583.19 EON97941.1 - 4.8e-07 29.7 0.1 1.1e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON97941.1 - 0.0013 18.9 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON97941.1 - 0.006 16.6 0.0 0.01 15.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON97941.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.11 EON97942.1 - 1.7e-31 109.2 26.2 1.7e-31 109.2 18.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON97942.1 - 2.7e-14 52.6 12.9 2.7e-14 52.6 8.9 3.2 2 2 0 3 3 3 1 Sugar (and other) transporter KAR9 PF08580.5 EON97943.1 - 1e-128 430.5 0.0 1.3e-128 430.2 0.0 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 EON97943.1 - 0.097 13.0 8.4 17 5.8 0.1 4.5 3 2 1 4 4 4 0 Syntaxin 6, N-terminal DNA_photolyase PF00875.13 EON97943.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA photolyase Prefoldin_2 PF01920.15 EON97943.1 - 4.1 7.2 9.7 6.5 6.5 0.2 3.8 4 0 0 4 4 4 0 Prefoldin subunit WD40 PF00400.27 EON97944.1 - 5.3e-55 181.4 13.4 1.3e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EON97944.1 - 0.0017 16.5 4.3 4.1 5.4 0.1 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 NARP1 PF12569.3 EON97945.1 - 0.0099 14.6 2.0 0.0099 14.6 1.4 2.8 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 WHIM2 PF15613.1 EON97945.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Macoilin PF09726.4 EON97945.1 - 4.9 5.3 27.3 7.6 4.6 18.9 1.3 1 0 0 1 1 1 0 Transmembrane protein tRNA-synt_His PF13393.1 EON97946.1 - 1.9e-38 132.2 0.0 1.2e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EON97946.1 - 1.2e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EON97946.1 - 6.2e-12 45.2 0.0 1.4e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EON97946.1 - 1.4e-05 24.0 0.1 0.04 12.6 0.1 3.1 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Mito_carr PF00153.22 EON97947.1 - 2.4e-50 168.2 8.4 5.7e-19 67.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EON97948.1 - 8.9e-14 50.7 1.9 0.14 12.0 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat adh_short PF00106.20 EON97949.1 - 3e-08 33.7 0.0 4.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON97949.1 - 4.6e-06 26.4 0.0 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF258 PF03193.11 EON97949.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fimbrial_PilY2 PF14481.1 EON97950.1 - 0.064 12.6 0.1 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Amino_oxidase PF01593.19 EON97951.1 - 3.3e-70 237.4 0.0 4.2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.14 EON97951.1 - 1.1e-06 28.7 10.0 4.1e-06 26.9 3.4 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EON97951.1 - 2.6e-06 27.6 3.7 2.6e-06 27.6 2.6 1.7 2 0 0 2 2 2 1 HMG-box domain MFS_1 PF07690.11 EON97952.1 - 1.1e-15 57.2 13.4 1.3e-15 56.9 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 EON97953.1 - 1.4e-07 31.3 10.8 2.6e-07 30.4 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EON97953.1 - 0.011 15.9 0.1 0.036 14.3 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON97953.1 - 0.72 10.3 0.0 0.72 10.3 0.0 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger DUF1275 PF06912.6 EON97955.1 - 2.5e-29 101.9 14.0 3.2e-29 101.6 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2062 PF09835.4 EON97955.1 - 0.012 15.1 1.1 0.012 15.1 0.7 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2177 PF09945.4 EON97955.1 - 0.046 13.7 0.3 0.086 12.8 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) BioY PF02632.9 EON97955.1 - 0.59 9.7 7.8 0.12 11.9 1.5 2.1 2 0 0 2 2 2 0 BioY family DUF4131 PF13567.1 EON97955.1 - 1.7 8.0 10.4 1.8 7.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RTA1 PF04479.8 EON97956.1 - 6.4e-13 48.7 4.3 7.9e-13 48.4 3.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Pex2_Pex12 PF04757.9 EON97957.1 - 2.4e-44 151.4 5.0 3e-44 151.1 3.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EON97957.1 - 1.4e-11 43.9 8.6 2.3e-11 43.3 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EON97957.1 - 3.7e-11 42.8 8.2 5.7e-11 42.2 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON97957.1 - 6.1e-10 38.6 5.2 9.1e-10 38.0 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON97957.1 - 2.2e-09 36.8 6.5 3.3e-09 36.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EON97957.1 - 1e-08 34.7 5.5 1.6e-08 34.1 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EON97957.1 - 2.5e-06 27.2 7.9 3.9e-06 26.6 5.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EON97957.1 - 1.9e-05 24.3 2.8 3.7e-05 23.4 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EON97957.1 - 0.00038 20.5 7.9 0.0011 19.0 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EON97957.1 - 0.0025 17.2 0.9 0.0043 16.5 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EON97957.1 - 0.0074 15.9 4.9 0.015 14.9 3.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EON97957.1 - 0.09 12.3 7.9 0.16 11.5 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EON97957.1 - 0.25 11.1 3.5 0.42 10.4 2.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 EON97957.1 - 2.3 8.1 7.0 6.4 6.7 4.9 1.7 1 1 0 1 1 1 0 IBR domain DUF4110 PF13422.1 EON97958.1 - 1.5e-27 95.2 0.1 1.5e-27 95.2 0.1 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EON97958.1 - 9.2e-27 92.5 14.5 5.3e-09 35.9 0.1 6.6 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EON97958.1 - 5e-19 67.8 3.6 1e-07 31.7 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EON97958.1 - 1.1e-17 63.4 17.0 7.9e-06 25.5 0.0 6.5 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EON97958.1 - 2.2e-14 52.8 3.8 0.00089 19.3 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EON97958.1 - 1.6e-13 49.8 1.4 0.016 14.9 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EON97958.1 - 1.1e-11 44.0 0.5 2e-05 24.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif zf-CCCH_2 PF14608.1 EON97959.1 - 6.3e-08 32.3 52.7 6e-07 29.2 6.2 5.5 5 1 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EON97959.1 - 0.003 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Cupin_8 PF13621.1 EON97960.1 - 1.8e-18 66.9 0.1 1.4e-17 64.0 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EON97960.1 - 4.7e-10 39.7 0.1 1.6e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase TFIIF_alpha PF05793.7 EON97960.1 - 0.11 10.8 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cupin_4 PF08007.7 EON97960.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Glyco_transf_22 PF03901.12 EON97961.1 - 1e-41 143.3 23.8 1.4e-41 142.8 16.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family R3H PF01424.17 EON97962.1 - 4.6e-15 55.0 0.0 8.1e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain DUF3072 PF11272.3 EON97962.1 - 0.67 9.6 0.0 0.67 9.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) DEAD PF00270.24 EON97963.1 - 3.3e-44 150.3 3.0 3.9e-44 150.1 1.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON97963.1 - 9e-28 95.9 0.1 6.2e-27 93.2 0.1 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON97963.1 - 0.00088 19.1 0.2 0.0018 18.1 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EON97963.1 - 0.0033 17.0 0.4 0.0089 15.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EON97963.1 - 0.014 15.1 0.1 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EON97963.1 - 0.019 15.0 0.2 0.07 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EON97963.1 - 0.037 13.3 0.2 0.055 12.7 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 EON97963.1 - 0.041 13.6 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.1 EON97963.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 EON97963.1 - 0.073 12.1 0.2 0.29 10.2 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 EON97963.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Helicase Fanconi_A PF03511.9 EON97963.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein DAD PF02109.11 EON97964.1 - 3.4e-43 146.2 0.9 4.3e-43 145.9 0.6 1.0 1 0 0 1 1 1 1 DAD family F_actin_cap_B PF01115.12 EON97965.1 - 1e-106 355.5 0.0 1.2e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF1295 PF06966.7 EON97967.1 - 2.1e-12 46.8 1.6 5.2e-12 45.5 1.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EON97967.1 - 2.1e-05 23.2 2.9 9e-05 21.1 2.0 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EON97967.1 - 0.05 13.7 0.2 0.33 11.0 0.1 2.2 1 1 1 2 2 2 0 Phospholipid methyltransferase DUF422 PF04240.7 EON97967.1 - 0.22 10.9 2.9 1.9 7.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF422) Peptidase_S9 PF00326.16 EON97968.1 - 1.6e-51 174.5 0.0 3.5e-51 173.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EON97968.1 - 5.5e-11 42.4 0.0 9.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EON97968.1 - 3.4e-05 23.3 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 EON97968.1 - 0.03 12.8 0.0 0.38 9.2 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PWI PF01480.12 EON97969.1 - 3.4e-29 100.7 0.1 5.7e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain DUF1282 PF06930.7 EON97970.1 - 8.8e-05 22.2 0.4 9.2e-05 22.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) AA_permease_2 PF13520.1 EON97970.1 - 0.0092 14.5 0.3 0.01 14.4 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.12 EON97970.1 - 0.016 14.6 1.3 0.018 14.5 0.9 1.1 1 0 0 1 1 1 0 Yip1 domain SVM_signal PF12113.3 EON97970.1 - 0.017 14.9 1.5 0.03 14.1 1.1 1.3 1 0 0 1 1 1 0 SVM protein signal sequence DUF4234 PF14018.1 EON97970.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) IlvGEDA_leader PF08046.6 EON97970.1 - 0.19 10.8 1.9 0.35 10.0 1.3 1.5 1 0 0 1 1 1 0 IlvGEDA operon leader peptide DUF4064 PF13273.1 EON97970.1 - 0.65 10.1 4.6 5.6 7.1 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Glyco_hydro_16 PF00722.16 EON97971.1 - 6.5e-43 146.1 1.5 1.4e-42 145.0 1.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3602 PF12223.3 EON97972.1 - 2.4e-18 66.2 16.6 2.7e-13 50.0 3.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) TMF_TATA_bd PF12325.3 EON97973.1 - 5.1e-40 135.9 9.2 5.1e-40 135.9 6.4 5.2 2 2 1 4 4 4 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EON97973.1 - 1.9e-07 30.8 5.4 1.9e-07 30.8 3.7 9.0 2 2 7 9 9 8 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EON97973.1 - 0.00026 20.7 84.6 0.038 13.7 13.2 5.7 2 2 2 4 4 4 3 TPR/MLP1/MLP2-like protein Filament PF00038.16 EON97973.1 - 0.014 14.8 68.5 0.13 11.7 33.4 3.3 2 1 1 3 3 3 0 Intermediate filament protein Tropomyosin_1 PF12718.2 EON97973.1 - 0.016 15.0 21.8 0.016 15.0 15.1 4.5 3 1 1 4 4 4 0 Tropomyosin like Reo_sigmaC PF04582.7 EON97973.1 - 0.045 12.9 21.9 0.093 11.8 1.1 4.0 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Trans_reg_C PF00486.23 EON97973.1 - 0.056 13.3 1.2 0.7 9.8 0.1 2.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal GAS PF13851.1 EON97973.1 - 0.27 10.3 71.5 1 8.5 8.6 4.6 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 EON97973.1 - 1.4 8.6 22.9 1.2 9.0 0.4 4.4 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EON97973.1 - 1.9 5.6 75.3 1.6 6.0 31.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) DUF4298 PF14131.1 EON97973.1 - 1.9 8.3 14.7 6.4 6.7 0.1 5.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4298) CENP-F_leu_zip PF10473.4 EON97973.1 - 2.6 7.8 80.8 0.54 10.1 4.6 6.1 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FOLN PF09289.5 EON97974.1 - 0.055 13.3 0.3 0.097 12.5 0.2 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Mon1 PF03164.9 EON97975.1 - 1.5e-112 376.2 0.0 1.8e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 MMgT PF10270.4 EON97976.1 - 8.2e-32 109.8 0.0 9.4e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter WLM PF08325.5 EON97977.1 - 4.6e-53 179.8 0.5 1.1e-52 178.6 0.1 1.8 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EON97977.1 - 1.9e-08 34.3 2.3 1.9e-08 34.3 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 CHGN PF05679.11 EON97977.1 - 0.063 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Abhydrolase_5 PF12695.2 EON97978.1 - 2e-23 82.7 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON97978.1 - 3.1e-18 66.5 0.0 1.2e-16 61.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97978.1 - 1.3e-07 31.4 0.1 0.00016 21.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EON97978.1 - 1.6e-06 26.8 0.0 0.14 10.6 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EON97978.1 - 1.6e-05 24.4 0.0 0.016 14.6 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EON97978.1 - 5.4e-05 22.7 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.7 EON97978.1 - 7.7e-05 21.5 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 EON97978.1 - 0.00025 20.3 0.0 0.0025 17.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EON97978.1 - 0.00084 18.6 0.0 0.18 11.0 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EON97978.1 - 0.0015 18.2 0.0 0.087 12.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EON97978.1 - 0.0024 17.4 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON97978.1 - 0.018 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EON97978.1 - 0.044 13.1 0.0 6.9 6.0 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 EON97978.1 - 0.07 12.7 0.3 0.41 10.1 0.2 2.3 1 1 0 1 1 1 0 PGAP1-like protein Abhydro_lipase PF04083.11 EON97978.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Esterase PF00756.15 EON97978.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cupin_2 PF07883.6 EON97979.1 - 1.7e-08 33.8 0.0 2.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain SNF2_N PF00176.18 EON97980.1 - 1.8e-57 194.4 0.0 2.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON97980.1 - 1.5e-12 47.2 0.1 9.2e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON97980.1 - 6.8e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EON97980.1 - 3.4e-05 23.3 0.0 9.2e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.26 EON97980.1 - 0.0017 18.1 0.1 0.0041 16.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DEAD_2 PF06733.10 EON97980.1 - 0.019 14.3 0.5 0.051 12.9 0.1 1.9 2 0 0 2 2 2 0 DEAD_2 AAA_22 PF13401.1 EON97980.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF2406 PF10295.4 EON97981.1 - 6.8e-21 74.5 0.1 6.8e-21 74.5 0.1 2.7 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Hydantoinase_B PF02538.9 EON97981.1 - 0.12 10.5 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Ribosomal_L35Ae PF01247.13 EON97982.1 - 2.8e-42 142.3 0.5 3.2e-42 142.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EON97982.1 - 0.00036 20.3 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.4 EON97982.1 - 0.36 10.5 1.7 1.3 8.7 0.2 2.1 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) Enolase_C PF00113.17 EON97983.1 - 3.3e-153 508.8 0.1 4.4e-153 508.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EON97983.1 - 3.4e-57 192.0 0.6 5.9e-57 191.2 0.2 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 EON97983.1 - 0.016 14.1 0.2 0.64 8.9 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EON97983.1 - 0.043 14.3 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF3356 PF11836.3 EON97983.1 - 0.065 13.0 0.4 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) TauD PF02668.11 EON97984.1 - 4.5e-19 69.1 0.1 5.3e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EON97985.1 - 2.2e-08 34.2 0.0 6.1e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON97985.1 - 2.8e-06 27.1 0.0 5.9e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON97985.1 - 0.00036 20.1 0.0 0.00057 19.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON97985.1 - 0.0025 17.0 0.0 0.03 13.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family NuA4 PF09340.5 EON97987.1 - 4.5e-26 90.3 0.1 7.8e-26 89.5 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 M_domain PF12938.2 EON97987.1 - 0.83 9.4 8.2 1.5 8.6 5.7 1.4 1 0 0 1 1 1 0 M domain of GW182 Ank_2 PF12796.2 EON97988.1 - 4.4e-59 196.7 0.0 5.8e-18 65.0 0.0 8.8 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EON97988.1 - 6.6e-44 146.9 5.3 0.00021 21.4 0.0 12.7 12 1 1 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.25 EON97988.1 - 2.2e-42 140.7 18.8 4.2e-07 29.4 0.0 14.5 16 1 0 16 16 16 7 Ankyrin repeat Ank_4 PF13637.1 EON97988.1 - 1.5e-41 140.0 0.2 2.2e-06 28.0 0.0 12.4 9 4 4 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON97988.1 - 2.6e-39 129.2 4.8 1.4e-05 24.8 0.0 14.4 16 1 0 16 16 16 6 Ankyrin repeat DUF1843 PF08898.5 EON97988.1 - 0.0015 18.5 0.2 2.6 8.1 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) Ion_trans PF00520.26 EON97989.1 - 1.4e-75 252.9 80.8 1e-29 103.2 9.0 4.9 5 0 0 5 5 5 4 Ion transport protein JSRP PF15312.1 EON97989.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein VMA21 PF09446.5 EON97990.1 - 1.5e-15 56.8 10.9 2e-15 56.4 7.6 1.2 1 0 0 1 1 1 1 VMA21-like domain dCMP_cyt_deam_1 PF00383.17 EON97991.1 - 1.8e-15 56.3 1.3 2.7e-15 55.8 0.2 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region adh_short_C2 PF13561.1 EON97991.1 - 6.5e-14 52.2 0.0 1.5e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON97991.1 - 1.3e-08 34.9 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase dCMP_cyt_deam_2 PF08211.6 EON97991.1 - 8.8e-06 25.7 0.6 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EON97991.1 - 0.05 12.9 0.6 1.8 7.8 0.0 2.2 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases RNA_polI_A34 PF08208.6 EON97993.1 - 4.3e-20 72.2 10.0 4.3e-20 72.2 7.0 5.9 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.4 EON97994.1 - 7.9 5.8 11.1 11 5.4 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Drc1-Sld2 PF11719.3 EON97995.1 - 4.5e-106 355.4 25.5 5.1e-106 355.3 17.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein CRAL_TRIO PF00650.15 EON97996.1 - 8.5e-38 129.3 0.0 1.5e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EON97996.1 - 2.3e-10 40.4 1.1 9.5e-10 38.4 0.1 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EON97996.1 - 0.00056 19.8 0.0 0.0046 16.8 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Sugar_tr PF00083.19 EON97997.1 - 2.3e-40 138.5 23.6 3.8e-40 137.8 16.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON97997.1 - 2.8e-16 59.1 24.1 2.8e-16 59.1 16.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.24 EON97998.1 - 1.6e-45 154.5 0.2 6.1e-45 152.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EON97998.1 - 7.7e-09 35.4 0.3 2.9e-08 33.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EON97998.1 - 4.8e-08 33.1 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EON97998.1 - 4.7e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EON97998.1 - 2e-06 27.9 2.0 0.001 19.1 0.0 2.9 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 EON97998.1 - 2.9e-06 26.3 0.0 6.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EON97998.1 - 0.00018 21.3 0.2 0.00083 19.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EON97998.1 - 0.00036 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EON97998.1 - 0.00037 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON97998.1 - 0.00054 20.7 0.1 0.0022 18.7 0.0 2.0 3 0 0 3 3 1 1 AAA domain NACHT PF05729.7 EON97998.1 - 0.00076 19.1 0.9 0.057 13.0 0.0 3.0 2 1 0 3 3 3 1 NACHT domain TIP49 PF06068.8 EON97998.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EON97998.1 - 0.0013 17.8 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EON97998.1 - 0.0013 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EON97998.1 - 0.0018 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EON97998.1 - 0.0026 17.4 0.0 0.0089 15.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EON97998.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EON97998.1 - 0.0044 17.3 1.1 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EON97998.1 - 0.0053 16.3 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EON97998.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EON97998.1 - 0.0054 16.3 0.8 0.018 14.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EON97998.1 - 0.0054 16.1 0.7 0.07 12.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EON97998.1 - 0.006 15.7 0.2 0.013 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EON97998.1 - 0.0066 16.0 0.2 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EON97998.1 - 0.0084 15.5 0.2 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 EON97998.1 - 0.0089 15.6 0.7 0.03 13.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EON97998.1 - 0.0091 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EON97998.1 - 0.0096 15.6 0.9 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase Viral_Hsp90 PF03225.9 EON97998.1 - 0.01 14.1 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Bac_DnaA PF00308.13 EON97998.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EON97998.1 - 0.019 14.0 1.0 0.45 9.5 0.0 2.7 3 0 0 3 3 3 0 KaiC Cast PF10174.4 EON97998.1 - 0.027 12.5 1.7 0.051 11.6 0.7 1.6 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Sigma54_activat PF00158.21 EON97998.1 - 0.04 13.4 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EON97998.1 - 0.058 12.1 0.1 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 EON97998.1 - 0.059 13.4 0.1 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EON97998.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EON97998.1 - 0.16 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bromodomain PF00439.20 EON97999.1 - 1.8e-19 69.4 1.0 4.5e-19 68.1 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EON97999.1 - 4.5e-10 39.1 0.0 1.5e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.1 EON97999.1 - 0.19 12.0 12.5 0.13 12.6 0.8 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 EON98000.1 - 1.8e-13 49.9 22.6 3.1e-13 49.1 14.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CR6_interact PF10147.4 EON98000.1 - 0.02 14.2 6.4 0.032 13.5 4.5 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RCC1 PF00415.13 EON98001.1 - 3.7e-32 110.3 2.8 6.3e-07 29.5 0.0 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EON98001.1 - 3.1e-13 48.9 19.5 1.4e-08 34.1 0.0 7.3 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Mito_carr PF00153.22 EON98002.1 - 1.4e-63 210.5 3.7 2.1e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 EON98003.1 - 1.4e-21 76.8 0.3 3.1e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 Sec34-like family TFIID_20kDa PF03847.8 EON98004.1 - 2.7e-18 66.0 0.0 4.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EON98004.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDK5_activator PF03261.10 EON98004.1 - 4.9 6.4 15.3 5.2 6.3 1.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein RRM_1 PF00076.17 EON98005.1 - 4e-12 45.5 0.0 6.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98005.1 - 8.9e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98005.1 - 2e-06 27.5 0.1 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSBA PF01323.15 EON98006.1 - 2e-38 131.9 0.0 2.3e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EON98006.1 - 0.00067 19.7 0.0 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 EON98006.1 - 0.014 14.9 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 EON98006.1 - 0.016 15.4 0.0 6.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EON98006.1 - 0.017 14.9 0.1 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain HypD PF01924.11 EON98006.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Mis14 PF08641.7 EON98007.1 - 9e-10 38.7 0.2 1.5e-09 38.0 0.1 1.5 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Seryl_tRNA_N PF02403.17 EON98007.1 - 0.62 10.0 3.4 0.9 9.5 1.4 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IGF2_C PF08365.6 EON98007.1 - 1.3 8.8 3.7 20 5.0 0.0 2.9 2 1 1 3 3 3 0 Insulin-like growth factor II E-peptide PAP2 PF01569.16 EON98008.1 - 2.5e-11 43.3 8.1 2.5e-11 43.3 5.6 2.8 1 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EON98008.1 - 4.2e-06 26.4 4.4 4.2e-06 26.4 3.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily Y_phosphatase PF00102.22 EON98010.1 - 8.7e-48 162.6 0.1 3e-46 157.6 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EON98010.1 - 0.0012 18.9 0.4 0.017 15.1 0.0 2.9 3 1 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.15 EON98010.1 - 0.0071 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EON98010.1 - 0.15 12.3 0.0 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Prefoldin PF02996.12 EON98011.1 - 6.5e-35 119.3 0.0 1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EON98011.1 - 0.00096 18.8 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 Prefoldin subunit Filament PF00038.16 EON98011.1 - 0.02 14.3 0.1 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein HR1 PF02185.11 EON98011.1 - 0.028 14.1 0.1 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 Hr1 repeat Syntaxin-6_N PF09177.6 EON98011.1 - 0.073 13.4 1.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Pkinase PF00069.20 EON98012.1 - 3.3e-68 229.6 0.0 4e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98012.1 - 7.7e-29 100.5 0.0 9.9e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON98012.1 - 2e-06 26.9 0.0 3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON98012.1 - 0.00027 20.7 0.1 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EON98012.1 - 0.0011 18.0 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EON98012.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Lgl_C PF08596.5 EON98013.1 - 2.9e-55 187.3 0.0 1.2e-43 149.1 0.0 2.3 1 1 1 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EON98013.1 - 1.7e-06 27.6 2.2 0.048 13.5 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EON98013.1 - 0.01 15.3 0.0 4.4 6.6 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Glyco_hydro_47 PF01532.15 EON98016.1 - 2e-168 560.7 0.0 3.3e-168 560.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3987 PF13148.1 EON98016.1 - 0.33 9.4 5.9 0.59 8.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Glyco_hydro_43 PF04616.9 EON98017.1 - 4e-18 65.5 4.2 4e-18 65.5 2.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 FRQ PF09421.5 EON98018.1 - 8.3e-47 159.6 9.4 9.5e-47 159.4 6.5 1.0 1 0 0 1 1 1 1 Frequency clock protein Amidohydro_1 PF01979.15 EON98019.1 - 2.2e-20 73.6 0.0 2.5e-18 66.8 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EON98019.1 - 4.9e-14 51.8 0.1 2.1e-13 49.8 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EON98019.1 - 7.4e-10 39.3 1.3 1.6e-08 34.9 0.9 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EON98019.1 - 1.6e-06 27.6 0.5 0.00027 20.3 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family US22 PF02393.11 EON98019.1 - 0.11 12.5 0.1 3.9 7.5 0.0 2.2 2 0 0 2 2 2 0 US22 like Ribonuc_L-PSP PF01042.16 EON98020.1 - 2.9e-30 104.5 0.0 5e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP LETM1 PF07766.8 EON98020.1 - 2.3e-08 33.4 0.0 1.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 LETM1-like protein Clp1 PF06807.9 EON98021.1 - 0.00088 19.0 0.0 0.0018 18.0 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Slu7 PF11708.3 EON98021.1 - 0.012 15.3 1.8 0.017 14.9 1.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF768 PF05589.6 EON98021.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) RINT1_TIP1 PF04437.8 EON98022.1 - 1.9e-100 336.7 0.0 3.7e-100 335.8 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.1 EON98022.1 - 0.42 10.7 9.0 0.56 10.3 3.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Glyco_hydro_3 PF00933.16 EON98023.1 - 6.3e-93 311.0 0.0 9.6e-93 310.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON98023.1 - 8.3e-59 198.8 2.9 8.7e-59 198.7 0.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON98023.1 - 6.4e-12 45.2 0.0 1.5e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Fig1 PF12351.3 EON98024.1 - 7.7e-58 195.3 3.9 7.7e-58 195.3 2.7 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EON98024.1 - 1e-09 38.2 8.2 1.3e-09 37.8 5.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EON98024.1 - 1.2e-05 24.4 5.4 1.2e-05 24.4 3.8 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) B12-binding PF02310.14 EON98024.1 - 0.07 12.9 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain DUF202 PF02656.10 EON98024.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EON98024.1 - 2 8.6 6.3 1.4 9.1 1.9 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF2976 PF11190.3 EON98024.1 - 2.7 7.5 0.0 2.7 7.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) VanZ PF04892.7 EON98025.1 - 8.8e-12 45.1 3.7 1.3e-11 44.6 2.6 1.2 1 0 0 1 1 1 1 VanZ like family Antimicrobial20 PF08256.6 EON98025.1 - 0.086 13.1 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Aurein-like antibiotic peptide RseC_MucC PF04246.7 EON98025.1 - 0.34 10.4 1.0 21 4.6 0.6 2.3 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NAD_binding_6 PF08030.7 EON98026.1 - 4.4e-16 59.1 0.0 6.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EON98026.1 - 3.9e-15 56.0 13.2 1.2e-14 54.4 9.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EON98026.1 - 2.4e-05 24.1 0.0 0.00014 21.7 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EON98026.1 - 3.2e-05 24.4 0.0 0.23 12.0 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain VWA_CoxE PF05762.9 EON98026.1 - 0.024 13.7 1.0 0.047 12.8 0.7 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DASH_Spc34 PF08657.5 EON98027.1 - 1.7e-52 178.6 0.2 9e-51 173.0 0.1 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 Acyl-CoA_dh_2 PF08028.6 EON98028.1 - 1.3e-07 31.8 1.1 1.9e-07 31.3 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON98028.1 - 0.07 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Rpn3_C PF08375.6 EON98029.1 - 1.2e-24 86.4 1.4 2.9e-24 85.2 1.0 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EON98029.1 - 2e-20 73.0 0.4 1.1e-19 70.6 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 EON98029.1 - 0.0067 16.2 0.1 0.022 14.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Cas1_AcylT PF07779.7 EON98030.1 - 3.3e-58 197.3 17.2 1.4e-56 191.9 11.9 2.7 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EON98030.1 - 9.2e-22 78.1 0.0 1.4e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MFS_1 PF07690.11 EON98031.1 - 1.9e-37 128.8 45.4 1.9e-37 128.8 31.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EON98032.1 - 3.1e-33 114.9 16.7 3.1e-33 114.9 11.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98032.1 - 5e-09 35.2 3.5 5e-09 35.2 2.5 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EON98032.1 - 0.0038 15.3 0.2 0.0079 14.3 0.2 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF456 PF04306.8 EON98032.1 - 5.9 6.9 18.6 0.067 13.2 2.8 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF456) AAA_2 PF07724.9 EON98033.1 - 0.07 13.0 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) CLTH PF10607.4 EON98034.1 - 6.2e-34 116.7 0.0 1.1e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EON98034.1 - 2.7e-05 23.7 0.1 5.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 LisH DUF4160 PF13711.1 EON98034.1 - 0.093 12.6 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Aminotran_3 PF00202.16 EON98035.1 - 5.3e-106 354.3 0.0 6.3e-106 354.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EON98035.1 - 0.00035 19.7 0.0 0.00065 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EON98035.1 - 0.0097 14.8 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_1 PF00515.23 EON98036.1 - 6.4e-34 114.1 12.8 6.1e-07 28.7 0.2 6.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EON98036.1 - 1.1e-31 108.3 17.7 2.2e-13 49.6 3.3 4.6 3 2 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 EON98036.1 - 6.9e-30 100.5 13.0 4e-06 26.3 0.0 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EON98036.1 - 2e-23 80.3 9.0 2.9e-05 23.5 1.4 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EON98036.1 - 2.5e-19 68.9 13.0 2.2e-05 24.2 3.4 4.7 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EON98036.1 - 1.7e-18 65.1 9.0 0.0022 18.0 0.6 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EON98036.1 - 4.6e-16 59.0 17.1 6.5e-07 29.8 1.1 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EON98036.1 - 1.4e-15 55.7 9.9 0.003 17.2 0.0 5.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EON98036.1 - 1.8e-15 56.0 10.6 0.028 15.0 0.0 6.6 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EON98036.1 - 2.1e-15 56.8 14.9 1.2e-06 28.7 3.9 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EON98036.1 - 1.1e-11 44.3 10.7 0.014 15.7 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EON98036.1 - 2.6e-07 30.6 18.3 8.9e-05 22.5 5.0 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EON98036.1 - 1.4e-05 24.8 8.8 0.026 14.3 0.1 4.8 3 2 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 EON98036.1 - 1.6e-05 24.6 4.9 0.6 10.0 0.5 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat FAT PF02259.18 EON98036.1 - 7.8e-05 21.8 2.5 0.08 11.9 0.1 2.6 1 1 1 2 2 2 2 FAT domain Sel1 PF08238.7 EON98036.1 - 0.0013 19.2 8.1 11 6.8 0.1 5.1 5 0 0 5 5 5 0 Sel1 repeat APP_E2 PF12925.2 EON98036.1 - 0.008 15.7 8.2 0.24 10.9 0.9 3.0 1 1 2 3 3 3 1 E2 domain of amyloid precursor protein DUF2225 PF09986.4 EON98036.1 - 0.0094 15.4 7.6 0.48 9.8 0.1 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Phage_Gp111 PF07410.6 EON98036.1 - 0.051 13.7 0.5 0.17 12.0 0.1 2.0 2 1 0 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein TPR_20 PF14561.1 EON98036.1 - 0.11 12.6 7.4 1.6 8.9 2.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EON98036.1 - 0.12 11.0 8.1 0.9 8.2 1.0 2.6 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 EON98036.1 - 0.15 12.0 8.2 10 6.2 0.3 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EON98036.1 - 0.21 11.4 10.5 8.9 6.2 0.0 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat EIF_2_alpha PF07541.7 EON98036.1 - 0.22 11.2 1.6 6.4 6.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit Homeobox_KN PF05920.6 EON98037.1 - 5.6e-21 73.9 0.5 1e-20 73.1 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EON98037.1 - 1.7e-08 33.9 0.9 3.2e-08 33.0 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Tubulin_3 PF14881.1 EON98038.1 - 1e-83 279.2 0.1 1.5e-83 278.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EON98038.1 - 4.8e-12 45.9 0.0 1.4e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EON98038.1 - 0.018 14.9 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain HEAT PF02985.17 EON98039.1 - 2.1e-39 130.0 15.3 0.0049 16.8 0.0 13.2 13 1 1 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 EON98039.1 - 1.9e-25 88.9 4.7 1.4e-05 25.2 0.1 8.3 2 2 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 EON98039.1 - 2.7e-12 46.7 5.4 0.062 13.8 0.1 8.8 8 2 3 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EON98039.1 - 2.2e-10 40.7 5.8 0.017 15.4 0.1 7.3 5 2 2 8 8 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EON98039.1 - 3.1e-08 32.4 7.3 0.0029 16.0 0.3 4.9 3 2 2 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 EON98039.1 - 1.8e-07 30.7 1.2 0.22 10.8 0.0 4.7 4 1 1 5 5 5 3 CLASP N terminal DUF2435 PF10363.4 EON98039.1 - 0.00045 20.0 4.2 0.44 10.4 0.2 4.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) DNA_alkylation PF08713.6 EON98039.1 - 0.0036 16.8 0.0 7.6 5.9 0.0 3.3 1 1 2 3 3 3 1 DNA alkylation repair enzyme RIX1 PF08167.7 EON98039.1 - 0.021 14.4 0.2 0.88 9.2 0.0 3.4 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.18 EON98039.1 - 0.033 14.0 3.2 4.8 7.1 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EON98039.1 - 0.039 12.9 0.2 0.35 9.8 0.1 2.4 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EON98039.1 - 0.054 13.3 7.8 4.5 7.0 0.1 5.5 4 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EON98039.1 - 0.072 11.3 3.8 0.35 9.0 0.1 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit AAA_2 PF07724.9 EON98040.1 - 1.1e-46 158.8 0.0 3.8e-45 153.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EON98040.1 - 3.2e-27 95.3 0.0 9.5e-15 54.9 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EON98040.1 - 5.9e-24 83.7 0.7 3.2e-23 81.4 0.5 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EON98040.1 - 5.8e-17 62.2 10.7 6e-06 26.3 0.0 6.7 3 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EON98040.1 - 2.9e-16 59.4 0.0 2.3e-10 40.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EON98040.1 - 2.3e-14 53.6 0.0 3.3e-05 24.0 0.0 4.3 3 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EON98040.1 - 6.5e-09 35.4 0.0 2.3e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EON98040.1 - 1.2e-07 31.7 4.8 0.0096 15.6 0.1 5.5 5 1 1 6 6 6 1 Archaeal ATPase AAA_17 PF13207.1 EON98040.1 - 1.4e-07 32.3 6.3 0.011 16.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EON98040.1 - 4.6e-07 29.4 0.0 0.023 14.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.15 EON98040.1 - 6.5e-07 29.1 4.2 0.00025 20.8 0.0 3.9 3 0 0 3 3 3 1 Clp amino terminal domain AAA_19 PF13245.1 EON98040.1 - 7.3e-07 28.8 2.3 0.029 14.1 0.1 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 EON98040.1 - 3.4e-06 27.4 6.3 0.026 14.8 0.0 4.5 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EON98040.1 - 8e-06 25.1 0.1 0.16 11.1 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EON98040.1 - 1.7e-05 24.8 0.0 0.26 11.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EON98040.1 - 3.7e-05 23.6 0.0 0.21 11.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EON98040.1 - 5.7e-05 23.2 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EON98040.1 - 0.00017 20.5 0.1 0.026 13.4 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EON98040.1 - 0.00018 21.2 0.0 0.87 9.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EON98040.1 - 0.00019 21.0 0.0 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EON98040.1 - 0.00023 21.0 0.0 0.14 11.9 0.0 3.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EON98040.1 - 0.00028 20.3 1.2 1.8 7.9 0.0 4.1 4 1 1 5 5 4 2 AAA domain Zeta_toxin PF06414.7 EON98040.1 - 0.00055 19.0 0.0 0.054 12.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 EON98040.1 - 0.00055 20.2 0.2 0.78 10.0 0.0 3.3 3 0 0 3 3 2 1 ABC transporter DUF258 PF03193.11 EON98040.1 - 0.00095 18.3 0.0 0.44 9.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EON98040.1 - 0.001 18.5 0.0 0.82 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EON98040.1 - 0.0011 18.4 6.6 0.12 11.7 0.0 5.2 5 1 1 6 6 6 1 AAA-like domain AAA_24 PF13479.1 EON98040.1 - 0.0012 18.4 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EON98040.1 - 0.003 17.2 0.0 0.36 10.4 0.0 2.9 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EON98040.1 - 0.0035 17.0 0.0 0.27 10.9 0.0 3.4 3 0 0 3 3 3 1 NTPase Torsin PF06309.6 EON98040.1 - 0.007 16.2 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 Torsin SRP54 PF00448.17 EON98040.1 - 0.015 14.7 0.0 3.9 6.8 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EON98040.1 - 0.034 13.7 0.0 8.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EON98040.1 - 0.052 13.4 1.9 2.2 8.1 0.0 3.3 5 0 0 5 5 2 0 AAA domain MMR_HSR1 PF01926.18 EON98040.1 - 0.076 12.9 0.1 3.6 7.5 0.0 3.6 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EON98040.1 - 0.087 12.3 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EON98040.1 - 0.091 12.2 0.0 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Macoilin PF09726.4 EON98040.1 - 0.14 10.4 9.3 0.23 9.6 6.4 1.2 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EON98040.1 - 0.17 9.7 1.4 0.33 8.7 1.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EON98040.1 - 0.3 10.7 6.7 0.11 12.1 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Viral_P18 PF04521.8 EON98040.1 - 2.5 7.5 4.9 12 5.4 0.2 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ras PF00071.17 EON98042.1 - 6.3e-58 194.7 0.0 7.4e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON98042.1 - 3.7e-20 72.6 0.0 5.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON98042.1 - 1.4e-13 50.4 0.0 2.5e-13 49.6 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EON98042.1 - 7.2e-06 25.3 0.0 8.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EON98042.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EON98042.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EON98042.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EON98042.1 - 0.077 13.1 0.0 0.24 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain CAF1 PF04857.15 EON98043.1 - 2.1e-69 233.7 0.0 2.7e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 EON98043.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain Amidohydro_4 PF13147.1 EON98044.1 - 2.3e-11 44.2 1.6 2e-10 41.1 0.3 2.8 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EON98044.1 - 8.3e-10 38.8 0.0 2e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EON98044.1 - 3.5e-06 26.4 0.0 6.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Ferric_reduct PF01794.14 EON98045.1 - 1.5e-20 73.5 9.2 1.5e-20 73.5 6.4 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EON98045.1 - 1.3e-19 70.6 0.0 8.1e-11 42.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EON98045.1 - 8.5e-16 57.7 0.0 2.1e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain Zeta_toxin PF06414.7 EON98047.1 - 7.3e-52 175.3 0.0 1.4e-51 174.4 0.0 1.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EON98047.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EON98047.1 - 0.00044 19.7 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EON98047.1 - 0.007 16.3 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EON98047.1 - 0.034 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EON98047.1 - 0.044 13.4 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EON98047.1 - 0.049 12.8 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 EON98047.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CDC37_N PF03234.9 EON98049.1 - 4e-59 199.9 2.6 4e-59 199.9 1.8 2.8 2 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EON98049.1 - 1.5e-49 167.7 0.1 4.7e-49 166.1 0.0 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EON98049.1 - 1.1e-24 86.1 3.6 1.1e-24 86.1 2.5 2.6 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF1268 PF06896.6 EON98049.1 - 0.0017 18.7 0.8 0.0017 18.7 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1268) Spectrin PF00435.16 EON98049.1 - 0.0034 17.6 0.8 0.0034 17.6 0.6 2.9 3 0 0 3 3 3 1 Spectrin repeat XPG_I_2 PF12813.2 EON98049.1 - 0.024 14.1 0.0 0.096 12.1 0.0 1.9 1 0 0 1 1 1 0 XPG domain containing DUF2762 PF10960.3 EON98049.1 - 0.34 10.6 3.8 0.23 11.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF3887 PF13026.1 EON98049.1 - 2.7 8.3 10.2 0.13 12.6 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) AhpC-TSA_2 PF13911.1 EON98050.1 - 3e-10 40.0 0.0 4.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EON98050.1 - 0.0014 18.2 0.0 0.0031 17.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Rtf2 PF04641.7 EON98050.1 - 0.028 13.6 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Redoxin PF08534.5 EON98050.1 - 0.12 11.8 0.0 3.5 7.1 0.0 2.1 1 1 0 1 1 1 0 Redoxin KTI12 PF08433.5 EON98051.1 - 3.5e-64 216.6 0.0 5.9e-64 215.8 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EON98051.1 - 3.2e-05 23.8 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EON98051.1 - 0.0016 19.2 0.2 0.0045 17.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON98051.1 - 0.0032 17.7 0.0 0.015 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EON98051.1 - 0.039 14.0 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EON98051.1 - 0.11 12.4 0.0 0.44 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain ThiF PF00899.16 EON98052.1 - 4.5e-13 49.2 0.0 8.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Cornichon PF03311.9 EON98052.1 - 0.038 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Cornichon protein NUDIX_2 PF13869.1 EON98054.1 - 7.5e-80 266.6 0.0 9.2e-80 266.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase CLU PF13236.1 EON98055.1 - 7.5e-82 274.0 0.0 1.7e-81 272.8 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 EON98055.1 - 1.3e-51 174.8 0.0 4.3e-51 173.2 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EON98055.1 - 3.9e-25 87.7 0.2 8.9e-25 86.6 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EON98055.1 - 4e-25 87.5 9.3 1.9e-13 50.1 0.1 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EON98055.1 - 1.5e-17 62.8 0.0 0.0003 20.6 0.0 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EON98055.1 - 2.6e-08 33.4 5.5 0.11 12.1 0.0 3.7 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 EON98055.1 - 0.00029 20.5 10.5 0.23 11.4 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EON98055.1 - 0.00032 20.2 4.3 0.32 10.8 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EON98055.1 - 0.0058 16.7 1.4 99 3.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EON98055.1 - 0.13 11.9 2.0 15 5.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EON98055.1 - 0.3 11.8 8.0 8.2 7.2 0.0 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 EON98056.1 - 2.5e-23 81.9 0.6 2.8e-23 81.7 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EON98056.1 - 0.0056 16.6 0.4 0.21 11.6 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 EON98056.1 - 0.018 15.0 1.2 0.032 14.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 EON98056.1 - 0.022 14.6 2.1 0.056 13.3 1.4 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I zf-CHY PF05495.7 EON98056.1 - 0.027 14.6 0.9 5.7 7.1 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger DUF3268 PF11672.3 EON98056.1 - 0.039 14.0 1.1 0.7 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Evr1_Alr PF04777.8 EON98056.1 - 0.069 13.0 2.1 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Kri1_C PF12936.2 EON98057.1 - 2.6e-27 94.6 0.3 2.6e-27 94.6 0.2 3.4 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EON98057.1 - 4e-27 94.4 23.4 4e-27 94.4 16.2 5.0 5 1 1 6 6 6 1 KRI1-like family SMC_N PF02463.14 EON98058.1 - 2.5e-62 210.0 0.2 3.9e-62 209.3 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EON98058.1 - 2.8e-25 88.6 0.0 9.9e-25 86.8 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EON98058.1 - 1.2e-18 68.2 9.5 1.2e-18 68.2 6.6 6.8 3 2 3 6 6 6 1 AAA domain AAA_21 PF13304.1 EON98058.1 - 3.5e-15 56.7 1.4 2.6e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EON98058.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EON98058.1 - 0.0041 16.3 5.7 0.0041 16.3 3.9 7.6 3 2 4 7 7 7 1 Growth-arrest specific micro-tubule binding Arteri_GP4 PF02497.10 EON98058.1 - 0.0044 16.9 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Arterivirus glycoprotein ABC_tran PF00005.22 EON98058.1 - 0.32 11.3 0.0 0.32 11.3 0.0 6.8 3 2 0 3 3 3 0 ABC transporter Prp18 PF02840.10 EON98059.1 - 4.7e-52 175.6 1.5 6.3e-52 175.2 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EON98059.1 - 2.6e-11 42.5 2.6 2.6e-11 42.5 1.8 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Nop14 PF04147.7 EON98059.1 - 0.23 9.3 20.0 0.28 9.0 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 EON98059.1 - 3.4 6.0 28.2 5.6 5.3 19.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EON98059.1 - 3.4 5.2 5.5 3.5 5.2 3.8 1.1 1 0 0 1 1 1 0 Ycf1 Selenoprotein_S PF06936.6 EON98059.1 - 3.5 7.1 13.3 6 6.3 9.2 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) U79_P34 PF03064.11 EON98059.1 - 3.9 6.9 13.5 6.6 6.1 9.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC27 PF09507.5 EON98059.1 - 4.2 6.5 25.4 5.8 6.0 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1996 PF09362.5 EON98060.1 - 9e-50 169.5 0.8 1.2e-49 169.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EON98060.1 - 7.1e-19 67.5 9.6 1.9e-18 66.1 6.7 1.8 1 0 0 1 1 1 1 WSC domain DUF605 PF04652.11 EON98060.1 - 0.25 10.7 8.0 0.43 9.9 5.5 1.3 1 0 0 1 1 1 0 Vta1 like B3_4 PF03483.12 EON98062.1 - 9.9e-26 90.2 0.1 1.7e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EON98062.1 - 1.2e-17 63.5 0.0 2.4e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EON98062.1 - 0.037 13.0 0.1 0.065 12.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein tRNA-synt_2d PF01409.15 EON98062.1 - 0.048 12.8 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) PEP_mutase PF13714.1 EON98063.1 - 6.5e-48 163.0 5.2 7.4e-48 162.8 3.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EON98063.1 - 5.8e-19 67.6 2.3 7.7e-19 67.3 1.6 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Apc3 PF12895.2 EON98064.1 - 2e-21 75.9 1.8 2e-21 75.9 1.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EON98064.1 - 2.4e-05 23.9 6.8 0.0096 15.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON98064.1 - 3e-05 23.8 4.8 0.0062 16.4 0.2 3.4 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON98064.1 - 4.2e-05 24.0 2.7 0.6 10.8 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EON98064.1 - 0.00011 21.6 1.9 0.0041 16.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON98064.1 - 0.00017 21.8 0.7 0.71 10.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EON98064.1 - 0.00025 21.3 6.4 0.087 13.4 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EON98064.1 - 0.00042 19.9 9.2 0.026 14.1 1.5 2.8 2 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 EON98064.1 - 0.0011 19.2 0.6 0.32 11.3 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EON98064.1 - 0.0016 18.0 0.2 0.25 11.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON98064.1 - 0.082 12.7 0.3 5.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EON98065.1 - 8.6e-48 162.4 0.1 1.6e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EON98065.1 - 1.2e-05 25.1 0.0 4.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.7 EON98065.1 - 0.0014 17.9 0.5 0.0045 16.2 0.0 2.0 2 1 0 2 2 2 1 Rtf2 RING-finger RRM_1 PF00076.17 EON98066.1 - 5.1e-16 58.0 0.0 7.2e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98066.1 - 2.6e-12 46.5 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98066.1 - 7.8e-09 35.2 0.1 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N PF02798.15 EON98067.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EON98067.1 - 1.4e-08 34.8 0.0 3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EON98067.1 - 2e-07 30.9 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EON98067.1 - 4.4e-05 23.3 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EON98067.1 - 8.4e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EON98067.1 - 0.0011 19.3 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M24 PF00557.19 EON98068.1 - 3.8e-57 193.1 0.2 5.5e-57 192.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EON98068.1 - 1e-23 83.2 0.0 7.1e-23 80.4 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SAM_2 PF07647.12 EON98069.1 - 1.1e-10 41.1 0.1 2e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EON98069.1 - 4.6e-06 26.7 0.3 9.2e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EON98069.1 - 0.029 14.2 0.2 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif PI3_PI4_kinase PF00454.22 EON98071.1 - 8.2e-33 113.8 0.0 1.2e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DNA_repr_REX1B PF14966.1 EON98071.1 - 0.1 13.0 0.0 1.5 9.2 0.0 2.6 3 0 0 3 3 3 0 DNA repair REX1-B SBDS_C PF09377.5 EON98072.1 - 9.9e-52 173.8 0.0 1.4e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EON98072.1 - 1.4e-28 98.5 0.1 2.7e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF2636 PF11120.3 EON98074.1 - 0.15 11.5 4.5 0.27 10.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) DUF3397 PF11877.3 EON98074.1 - 1.4 8.9 9.8 0.24 11.4 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3397) RhoGAP PF00620.22 EON98075.1 - 1.3e-38 131.9 0.0 2.1e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 EON98075.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family Pkinase PF00069.20 EON98076.1 - 5.7e-09 35.5 0.7 8.1e-09 35.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98076.1 - 0.00028 20.0 1.2 0.00029 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PGBA_C PF15437.1 EON98076.1 - 0.055 13.6 16.7 0.11 12.6 11.6 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Defensin_propep PF00879.13 EON98076.1 - 1.2 9.1 6.5 2.7 8.0 4.5 1.6 1 0 0 1 1 1 0 Defensin propeptide DUF2229 PF09989.4 EON98076.1 - 1.7 8.0 3.8 2.4 7.5 2.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Rtf2 PF04641.7 EON98076.1 - 2 7.5 11.2 3 6.9 7.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Ribosomal_S13 PF00416.17 EON98077.1 - 1.4e-41 141.2 1.9 1.7e-41 140.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EON98077.1 - 0.0075 14.8 0.0 0.0079 14.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EON98077.1 - 0.072 13.1 0.5 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Methyltransf_28 PF02636.12 EON98078.1 - 7.6e-46 156.5 0.0 8.6e-32 110.5 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Gtr1_RagA PF04670.7 EON98079.1 - 2.1e-52 177.6 0.2 2.5e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Syntaxin_2 PF14523.1 EON98082.1 - 6.6 6.8 10.5 0.11 12.5 0.5 3.0 4 0 0 4 4 4 0 Syntaxin-like protein FAD_binding_6 PF00970.19 EON98083.1 - 1.6e-26 92.3 0.0 2.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EON98083.1 - 7.8e-26 90.7 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EON98083.1 - 0.00028 20.8 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EON98083.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Lung_7-TM_R PF06814.8 EON98085.1 - 6.6e-70 235.3 18.7 8.1e-70 235.0 13.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4492 PF14899.1 EON98085.1 - 0.11 11.9 2.3 0.14 11.7 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) EMP24_GP25L PF01105.19 EON98085.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1980 PF09323.5 EON98085.1 - 1.2 8.8 3.5 0.35 10.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Alg6_Alg8 PF03155.10 EON98086.1 - 3.2e-142 474.6 28.1 4e-142 474.3 19.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_S10 PF00450.17 EON98087.1 - 2.8e-131 438.5 0.2 3.6e-131 438.1 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EON98087.1 - 1.6e-09 37.9 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EON98087.1 - 1.2e-05 25.3 0.0 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family CATSPERG PF15064.1 EON98088.1 - 0.08 10.6 0.0 0.1 10.3 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma His_biosynth PF00977.16 EON98090.1 - 1.2e-35 122.8 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EON98090.1 - 0.071 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 EON98090.1 - 0.075 12.2 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 PcrB family M20_dimer PF07687.9 EON98091.1 - 6.4e-13 48.4 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EON98091.1 - 7.4e-09 35.3 0.1 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EON98092.1 - 2.3e-32 112.1 26.9 3.6e-32 111.4 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EON98092.1 - 8.2 5.1 38.1 0.13 11.0 10.5 2.8 2 1 1 3 3 3 0 Acyltransferase family Lectin_leg-like PF03388.8 EON98093.1 - 3e-22 78.8 0.0 5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Leu_zip PF15294.1 EON98093.1 - 0.006 15.7 3.2 0.0086 15.2 2.2 1.1 1 0 0 1 1 1 1 Leucine zipper Baculo_PEP_C PF04513.7 EON98093.1 - 0.016 15.0 1.2 0.045 13.5 0.8 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2408 PF10303.4 EON98093.1 - 0.091 12.8 0.9 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Kelch_2 PF07646.10 EON98093.1 - 0.84 9.5 3.2 9.8 6.1 0.2 2.5 2 0 0 2 2 2 0 Kelch motif K_trans PF02705.11 EON98094.1 - 3.4e-179 596.6 14.1 4.6e-179 596.2 9.8 1.1 1 0 0 1 1 1 1 K+ potassium transporter zf-Tim10_DDP PF02953.10 EON98095.1 - 1.1e-20 72.6 3.9 1.5e-20 72.2 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EON98095.1 - 0.0068 15.8 2.3 0.016 14.6 1.6 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF2431 PF10354.4 EON98096.1 - 1.3e-56 191.0 0.0 1.7e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ADIP PF11559.3 EON98097.1 - 0.0017 18.2 1.6 0.0017 18.2 1.1 1.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Med9 PF07544.8 EON98097.1 - 0.049 13.3 0.7 0.049 13.3 0.5 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YscO PF07321.7 EON98097.1 - 0.072 12.9 16.4 0.34 10.7 9.6 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO AAA_13 PF13166.1 EON98097.1 - 0.39 9.1 3.7 0.56 8.6 2.5 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EON98097.1 - 1.8 8.1 9.5 0.62 9.6 4.7 1.6 2 0 0 2 2 2 0 IncA protein GBP_C PF02841.9 EON98097.1 - 2.2 7.3 12.9 3.3 6.8 8.9 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Nup188 PF10487.4 EON98098.1 - 1.2e-08 33.3 0.4 1.7e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pro-kuma_activ PF09286.6 EON98099.1 - 3.1e-32 111.5 0.0 4.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Rhodanese PF00581.15 EON98100.1 - 2e-09 37.7 0.0 4.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_transf_22 PF03901.12 EON98101.1 - 2.5e-14 53.1 0.5 3e-14 52.8 0.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 EON98101.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Adap_comp_sub PF00928.16 EON98102.1 - 4.9e-19 68.4 0.0 7.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EON98102.1 - 4.6e-08 32.8 0.1 7.6e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EON98102.1 - 0.051 13.6 0.4 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Adeno_knob PF00541.12 EON98102.1 - 0.08 12.5 0.0 5.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Adenoviral fibre protein (knob domain) UPF0047 PF01894.12 EON98103.1 - 6.4e-40 135.6 0.0 9.9e-40 135.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Peptidase_C2 PF00648.16 EON98104.1 - 7.6e-25 87.5 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EON98104.1 - 7.4e-15 54.8 0.0 5.2e-12 45.6 0.0 3.3 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EON98104.1 - 8.4e-06 25.5 3.2 1.5e-05 24.7 2.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PIG-X PF08320.7 EON98105.1 - 1.7e-65 220.1 0.0 3.4e-65 219.1 0.0 1.5 2 0 0 2 2 2 1 PIG-X / PBN1 E1-E2_ATPase PF00122.15 EON98106.1 - 4.5e-69 232.0 1.6 4.5e-69 232.0 1.1 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EON98106.1 - 2.3e-22 80.4 0.0 8.7e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EON98106.1 - 4.9e-13 49.6 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EON98106.1 - 1.9e-10 40.0 0.0 6.2e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EON98106.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON98106.1 - 0.0034 17.3 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit BRE1 PF08647.6 EON98107.1 - 7.4e-27 93.1 8.9 7.4e-27 93.1 6.1 5.7 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EON98107.1 - 1.7e-08 34.3 9.8 2.8e-08 33.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON98107.1 - 1.8e-08 33.9 7.5 2.8e-08 33.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON98107.1 - 1.8e-08 33.8 9.2 3.2e-08 33.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EON98107.1 - 2.2e-07 30.4 9.9 3.6e-07 29.7 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EON98107.1 - 4e-07 29.7 7.4 6.6e-07 29.0 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EON98107.1 - 8.6e-05 22.2 3.4 0.00017 21.3 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EON98107.1 - 0.00012 21.7 5.5 0.00032 20.3 3.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EON98107.1 - 0.00041 20.1 6.8 0.00081 19.2 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EON98107.1 - 0.00045 19.6 1.9 0.00086 18.8 1.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prefoldin_2 PF01920.15 EON98107.1 - 0.0019 17.9 8.4 0.0019 17.9 5.8 7.6 5 3 2 7 7 7 1 Prefoldin subunit DUF869 PF05911.6 EON98107.1 - 0.0019 16.5 14.4 0.0019 16.5 10.0 3.1 2 1 1 3 3 3 1 Plant protein of unknown function (DUF869) zf-rbx1 PF12678.2 EON98107.1 - 0.021 14.9 5.4 0.056 13.5 3.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C2H2_6 PF13912.1 EON98107.1 - 0.37 10.7 3.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_4 PF14570.1 EON98107.1 - 0.83 9.2 5.9 3.4 7.3 4.3 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 EON98107.1 - 0.86 8.7 25.2 1.2 8.2 5.0 3.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein FYVE PF01363.16 EON98107.1 - 3.4 7.6 11.0 40 4.2 7.8 2.3 1 1 1 2 2 2 0 FYVE zinc finger TPR_11 PF13414.1 EON98108.1 - 2.2e-20 72.0 20.7 3.2e-07 29.8 0.2 7.0 7 0 0 7 7 7 5 TPR repeat TPR_17 PF13431.1 EON98108.1 - 8.4e-14 50.5 1.9 0.061 13.5 0.1 7.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EON98108.1 - 1.4e-12 46.3 7.5 0.002 17.7 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EON98108.1 - 2.7e-12 47.0 18.2 0.011 16.4 0.0 7.5 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EON98108.1 - 6.5e-10 38.7 14.7 0.066 13.8 0.0 9.5 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 EON98108.1 - 4.8e-09 35.4 28.0 0.0051 16.6 0.0 9.6 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 EON98108.1 - 1.9e-08 34.4 10.7 0.2 12.0 0.6 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 EON98108.1 - 1e-07 31.9 13.0 0.0034 17.4 1.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON98108.1 - 5.6e-07 29.4 18.6 0.069 13.1 0.3 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EON98108.1 - 2.7e-06 26.7 20.5 0.018 14.6 0.0 6.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EON98108.1 - 0.0014 18.2 10.0 0.074 12.8 0.9 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON98108.1 - 0.011 16.0 15.6 0.32 11.5 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 EON98108.1 - 0.077 12.8 16.3 3 7.7 0.2 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Ribosomal_S3_C PF00189.15 EON98109.1 - 1.2e-16 60.6 0.1 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EON98109.1 - 2.3e-12 46.2 0.1 4.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EON98109.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Aminotran_3 PF00202.16 EON98110.1 - 3.7e-97 325.2 0.0 4.4e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EON98110.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Mito_carr PF00153.22 EON98111.1 - 3.7e-52 173.9 0.6 2.2e-17 62.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP_central PF04928.12 EON98112.1 - 1e-100 335.7 0.0 1.4e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EON98112.1 - 1.3e-47 161.2 0.1 2.5e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EON98112.1 - 7e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 EON98112.1 - 0.0019 17.9 0.1 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S49 Sedlin_N PF04628.8 EON98113.1 - 3.6e-41 140.0 0.0 4.2e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EON98113.1 - 0.00068 19.3 0.1 0.03 14.0 0.0 2.1 1 1 1 2 2 2 2 Sybindin-like family IGPS PF00218.16 EON98114.1 - 4.3e-98 327.4 0.0 9.5e-98 326.2 0.0 1.6 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EON98114.1 - 4.9e-51 172.9 0.0 1.3e-50 171.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 EON98114.1 - 4e-42 144.0 0.1 1.6e-41 142.0 0.0 2.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EON98114.1 - 1.9e-05 24.2 0.1 5.4e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EON98114.1 - 0.006 16.1 0.1 0.091 12.2 0.1 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PTCB-BRCT PF12738.2 EON98114.1 - 0.0061 16.3 0.1 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EON98114.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain His_biosynth PF00977.16 EON98114.1 - 0.042 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EON98114.1 - 0.055 12.3 0.2 0.15 10.9 0.1 1.7 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DEAD PF00270.24 EON98115.1 - 1.3e-39 135.3 0.5 3e-39 134.2 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON98115.1 - 8.1e-22 76.8 0.1 1.2e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EON98115.1 - 6.4e-05 22.8 1.6 0.00018 21.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Histone PF00125.19 EON98116.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EON98116.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EON98116.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EON98116.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EON98116.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EON98116.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Peptidase_M16_C PF05193.16 EON98117.1 - 2.5e-42 144.6 0.0 1.5e-22 80.1 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EON98117.1 - 2.8e-32 111.5 0.9 2e-31 108.7 0.0 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) NDUF_B4 PF07225.7 EON98118.1 - 0.00059 19.6 0.0 0.00067 19.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SPX PF03105.14 EON98119.1 - 0.0027 17.5 5.3 0.0051 16.6 3.7 1.5 1 1 0 1 1 1 1 SPX domain SlyX PF04102.7 EON98119.1 - 0.079 13.3 6.8 0.25 11.7 0.1 3.4 3 0 0 3 3 3 0 SlyX TPR_MLP1_2 PF07926.7 EON98119.1 - 0.2 11.3 20.0 0.11 12.2 10.2 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4320 PF14208.1 EON98119.1 - 0.23 11.4 1.0 0.91 9.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) FliT PF05400.8 EON98119.1 - 0.43 11.0 18.8 0.64 10.4 0.6 3.6 1 1 2 3 3 3 0 Flagellar protein FliT Vir_act_alpha_C PF10400.4 EON98119.1 - 0.62 10.4 7.9 1.2 9.5 1.7 2.7 1 1 1 2 2 2 0 Virulence activator alpha C-term PA26 PF04636.8 EON98119.1 - 0.81 8.3 7.6 0.65 8.6 4.4 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cytochrom_C_2 PF01322.15 EON98119.1 - 1.1 9.8 7.6 10 6.6 3.5 2.4 1 1 0 2 2 2 0 Cytochrome C' AATF-Che1 PF13339.1 EON98119.1 - 2.1 8.4 15.2 6.2 6.9 0.4 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.1 EON98119.1 - 5.2 5.9 11.9 24 3.7 8.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mg_trans_NIPA PF05653.9 EON98120.1 - 7.5e-104 346.8 12.3 9.3e-104 346.5 8.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EON98120.1 - 4.8e-09 36.4 1.9 4.8e-09 36.4 1.3 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EON98120.1 - 5.7e-05 23.1 6.0 5.7e-05 23.1 4.1 3.1 3 1 1 4 4 4 2 EamA-like transporter family MARVEL PF01284.18 EON98120.1 - 0.61 9.8 12.8 2 8.2 4.1 2.6 1 1 1 2 2 2 0 Membrane-associating domain Acyl_transf_3 PF01757.17 EON98120.1 - 2 7.1 16.4 0.28 9.9 4.2 2.2 1 1 1 2 2 2 0 Acyltransferase family Nol1_Nop2_Fmu PF01189.12 EON98121.1 - 6.8e-17 61.7 0.0 4.7e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family UCH PF00443.24 EON98122.1 - 6.3e-61 205.8 0.1 5.6e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EON98122.1 - 3e-13 49.8 0.0 7.1e-09 35.5 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Septin PF00735.13 EON98123.1 - 1.6e-09 37.2 0.0 1.5e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EON98123.1 - 0.0013 18.6 0.0 0.0034 17.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EON98123.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EON98123.1 - 0.0018 18.3 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EON98123.1 - 0.0018 18.7 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EON98123.1 - 0.0073 15.5 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EON98123.1 - 0.0094 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EON98123.1 - 0.0095 15.6 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 EON98123.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 EON98123.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EON98123.1 - 0.018 13.9 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EON98123.1 - 0.031 13.8 0.2 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EON98123.1 - 0.031 14.5 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EON98123.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EON98123.1 - 0.072 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EON98123.1 - 0.078 11.7 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family Zeta_toxin PF06414.7 EON98123.1 - 0.089 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EON98123.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EON98123.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Hpr_kinase_C PF07475.7 EON98123.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EON98123.1 - 0.14 12.9 0.0 0.45 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF1900 PF08954.6 EON98124.1 - 6.2e-50 168.2 0.0 4.4e-49 165.4 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EON98124.1 - 3e-34 116.4 0.1 6.6e-34 115.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EON98124.1 - 6.3e-26 89.2 4.1 6.9e-08 32.0 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EON98124.1 - 0.00018 19.8 0.0 0.077 11.1 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TMPIT PF07851.8 EON98124.1 - 0.044 12.8 1.9 0.066 12.2 1.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.6 EON98124.1 - 0.65 8.5 4.9 0.95 8.0 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2985 PF11204.3 EON98125.1 - 5e-38 128.7 3.3 7.3e-38 128.1 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) FHA PF00498.21 EON98126.1 - 4.6e-11 42.6 0.2 1.1e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 FHA domain MR_MLE_C PF13378.1 EON98127.1 - 2.2e-33 114.5 0.1 3.3e-32 110.7 0.0 2.9 3 0 0 3 3 3 1 Enolase C-terminal domain-like WD40 PF00400.27 EON98127.1 - 3.4e-20 71.1 15.6 5.7e-08 32.3 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat MR_MLE PF01188.16 EON98127.1 - 3.2e-10 40.3 0.0 9.4e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain BBS2_N PF14781.1 EON98127.1 - 0.049 13.2 0.0 0.31 10.6 0.0 2.3 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Cwf_Cwc_15 PF04889.7 EON98127.1 - 1.1 8.9 8.9 1.9 8.1 6.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SRI PF08236.6 EON98128.1 - 3.3e-22 78.2 10.3 9.2e-22 76.8 7.1 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EON98128.1 - 5.8e-22 78.7 0.1 5.8e-22 78.7 0.1 3.6 2 2 0 2 2 2 1 SET domain WW PF00397.21 EON98128.1 - 4.4e-05 23.2 1.4 9e-05 22.2 1.0 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 EON98128.1 - 0.00018 20.9 0.2 0.00073 18.9 0.2 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RPN7 PF10602.4 EON98131.1 - 5.7e-48 162.6 0.1 1e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EON98131.1 - 9.6e-16 58.0 0.1 2.6e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 PCI domain XkdW PF09636.5 EON98131.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 XkdW protein eIF-6 PF01912.13 EON98132.1 - 7.2e-83 276.5 1.3 1.1e-82 276.0 0.9 1.2 1 0 0 1 1 1 1 eIF-6 family CBFD_NFYB_HMF PF00808.18 EON98133.1 - 5e-13 48.9 2.0 7.9e-13 48.2 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EON98133.1 - 1.6e-05 24.8 0.2 2.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Tim44 PF04280.10 EON98133.1 - 0.06 13.3 0.3 0.092 12.7 0.2 1.4 1 1 0 1 1 1 0 Tim44-like domain Apc4 PF12896.2 EON98134.1 - 4.7e-40 137.1 0.1 7.3e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Fungal_trans PF04082.13 EON98135.1 - 4.6e-21 74.8 0.0 1.2e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Myb_DNA-binding PF00249.26 EON98136.1 - 2.2e-07 30.8 0.0 5.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EON98136.1 - 0.00019 21.4 0.7 0.00042 20.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain WAC_Acf1_DNA_bd PF10537.4 EON98137.1 - 5.7e-41 138.8 0.1 2.4e-40 136.8 0.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EON98137.1 - 1.5e-17 63.0 0.4 2.7e-17 62.2 0.3 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EON98137.1 - 1.9e-12 46.5 0.4 4.3e-12 45.4 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EON98137.1 - 0.00012 21.8 0.8 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 EON98137.1 - 0.0043 16.8 0.7 0.015 15.0 0.5 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DHQ_synthase PF01761.15 EON98137.1 - 0.36 9.6 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 3-dehydroquinate synthase adh_short_C2 PF13561.1 EON98138.1 - 3.2e-26 92.5 0.0 4.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON98138.1 - 1.8e-24 86.5 0.0 1.5e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase GST_N_3 PF13417.1 EON98138.1 - 2.2e-11 43.8 0.0 4.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EON98138.1 - 2.1e-10 40.4 0.0 4.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KR PF08659.5 EON98138.1 - 3.7e-09 36.5 0.0 7.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 KR domain GST_N_2 PF13409.1 EON98138.1 - 6.7e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EON98138.1 - 2.4e-06 27.5 0.0 7.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EON98138.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 EON98138.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_C_3 PF14497.1 EON98138.1 - 0.024 15.0 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_3 PF00202.16 EON98139.1 - 2.5e-51 174.5 0.0 3.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3535 PF12054.3 EON98140.1 - 1.1e-146 489.0 4.9 5.6e-146 486.6 2.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EON98140.1 - 8.6e-75 251.2 0.0 1.3e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON98140.1 - 1.7e-14 53.4 0.0 4.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EON98140.1 - 1.8e-14 52.4 8.8 0.015 15.3 0.0 8.9 10 0 0 10 10 10 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EON98140.1 - 3.3e-08 33.8 0.7 0.14 12.6 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EON98140.1 - 6.5e-06 26.4 6.9 6.7 7.3 0.0 9.2 10 0 0 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.1 EON98140.1 - 1.3e-05 25.3 14.4 0.0079 16.4 0.0 7.8 8 2 1 9 9 9 1 HEAT repeats CLASP_N PF12348.3 EON98140.1 - 0.01 15.2 0.5 2.1 7.6 0.3 3.5 3 1 0 3 3 3 0 CLASP N terminal Adaptin_N PF01602.15 EON98140.1 - 0.074 11.3 3.8 0.91 7.7 0.2 3.4 3 1 0 3 3 3 0 Adaptin N terminal region Anillin PF08174.6 EON98141.1 - 7.9e-37 126.4 0.2 2.7e-36 124.6 0.1 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EON98141.1 - 2e-08 34.3 0.0 6.6e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 PH domain Sulfotransfer_3 PF13469.1 EON98142.1 - 0.0011 19.8 0.0 0.003 18.5 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family SNF2_N PF00176.18 EON98143.1 - 7.8e-85 284.2 1.7 7.8e-85 284.2 1.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EON98143.1 - 1.2e-20 73.1 2.2 1.3e-20 73.1 0.1 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EON98143.1 - 2e-19 69.2 0.4 2.4e-17 62.5 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EON98143.1 - 1e-17 64.0 1.1 1e-17 64.0 0.7 4.2 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EON98143.1 - 5e-15 55.0 12.0 5e-15 55.0 8.3 4.2 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EON98143.1 - 3e-10 39.3 2.2 3e-10 39.3 1.5 2.6 2 0 0 2 2 2 1 QLQ E7 PF00527.13 EON98143.1 - 0.083 13.0 0.0 0.083 13.0 0.0 2.9 3 0 0 3 3 3 0 E7 protein, Early protein DUF4602 PF15375.1 EON98144.1 - 9 6.3 18.0 0.75 9.8 5.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) Myotub-related PF06602.9 EON98145.1 - 2.6e-125 417.8 0.0 3.4e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EON98145.1 - 0.0074 16.5 0.0 0.057 13.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF3156 PF11354.3 EON98145.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) DUF3543 PF12063.3 EON98146.1 - 4.6e-95 317.3 0.5 6.6e-95 316.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EON98146.1 - 8.7e-39 133.2 0.0 1.5e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98146.1 - 2.3e-23 82.5 0.0 4.9e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EON98146.1 - 0.032 13.9 0.3 0.094 12.4 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family ALMT PF11744.3 EON98147.1 - 0.04 12.5 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LTXXQ PF07813.7 EON98147.1 - 5.1 7.6 16.9 1.1 9.7 4.4 3.6 2 1 2 4 4 4 0 LTXXQ motif family protein Peptidase_C50 PF03568.12 EON98148.1 - 2.1e-115 385.5 0.0 2.5e-115 385.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EON98148.1 - 1.7e-06 27.4 0.0 0.0002 20.6 0.0 2.2 1 1 0 1 1 1 1 CHAT domain STE PF02200.11 EON98149.1 - 4.8e-62 206.9 0.2 8.5e-62 206.1 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EON98149.1 - 0.00012 22.1 2.9 0.22 11.9 2.0 2.7 1 1 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON98149.1 - 0.017 15.4 2.9 1.1 9.7 2.0 2.6 1 1 0 1 1 1 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 EON98150.1 - 0.0048 16.5 12.4 0.0074 15.9 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EON98150.1 - 0.024 14.4 6.8 0.036 13.8 4.7 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EON98150.1 - 1.5 8.9 14.6 2.2 8.3 10.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EON98150.1 - 5.5 6.7 13.9 8.3 6.2 9.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain ADH_zinc_N PF00107.21 EON98151.1 - 2.5e-20 72.3 0.0 4.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98151.1 - 2.6e-17 62.5 1.3 8.7e-17 60.8 1.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EON98151.1 - 0.01 15.4 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 EON98151.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nuc_sug_transp PF04142.10 EON98152.1 - 5.3e-09 35.5 0.1 9.3e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EON98152.1 - 6.5e-08 32.6 25.9 3e-05 24.0 3.2 3.2 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 EON98152.1 - 9.8e-07 27.9 5.4 1.5e-06 27.3 3.7 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EON98152.1 - 0.0006 19.4 20.1 0.01 15.4 5.9 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family CitMHS PF03600.11 EON98152.1 - 0.029 12.9 6.6 0.06 11.9 4.6 1.6 1 0 0 1 1 1 0 Citrate transporter Ferric_reduct PF01794.14 EON98152.1 - 2.3 8.3 8.7 0.85 9.7 2.0 2.7 3 0 0 3 3 3 0 Ferric reductase like transmembrane component ABC_membrane PF00664.18 EON98153.1 - 2.1e-77 260.2 37.8 5.5e-43 147.3 7.8 3.6 3 1 1 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.22 EON98153.1 - 3e-51 173.3 0.1 1.6e-29 102.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EON98153.1 - 2.7e-10 39.8 3.1 0.0018 17.5 0.1 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EON98153.1 - 2.5e-06 27.6 0.5 0.043 13.7 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EON98153.1 - 1.4e-05 24.3 0.3 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EON98153.1 - 2.3e-05 24.3 0.0 0.22 11.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EON98153.1 - 0.00012 22.4 0.3 0.03 14.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EON98153.1 - 0.00013 21.5 1.9 0.082 12.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EON98153.1 - 0.00062 19.2 0.4 1.9 8.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EON98153.1 - 0.00065 19.1 0.0 0.4 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EON98153.1 - 0.00086 19.7 0.3 2.4 8.6 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 EON98153.1 - 0.00095 19.2 0.8 2 8.2 0.0 3.8 3 1 1 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EON98153.1 - 0.0025 17.3 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.18 EON98153.1 - 0.004 16.9 0.6 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EON98153.1 - 0.005 16.6 0.7 0.33 10.7 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 EON98153.1 - 0.023 13.5 0.3 0.2 10.5 0.1 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 EON98153.1 - 0.026 14.1 0.4 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EON98153.1 - 0.033 14.3 0.4 7 6.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EON98153.1 - 0.042 14.0 0.0 9.7 6.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EON98153.1 - 0.083 13.7 0.0 4.6 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EON98153.1 - 0.16 11.0 0.1 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 EON98153.1 - 0.22 10.6 0.4 6.7 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family HLH PF00010.21 EON98154.1 - 3.2e-12 45.9 0.2 6.5e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EON98154.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Methyltransf_18 PF12847.2 EON98156.1 - 8e-19 68.2 0.1 1.3e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98156.1 - 3.3e-13 49.4 0.0 1.1e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON98156.1 - 3.4e-09 36.7 0.1 7e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98156.1 - 9.1e-09 35.6 0.0 2.5e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98156.1 - 4.2e-08 33.0 0.1 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98156.1 - 3.7e-06 27.3 0.1 1.4e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON98156.1 - 4.3e-06 27.0 0.0 7.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EON98156.1 - 9.6e-05 22.4 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 EON98156.1 - 0.00018 20.9 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EON98156.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EON98156.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EON98156.1 - 0.036 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EON98156.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cation_efflux PF01545.16 EON98157.1 - 1.7e-57 194.6 0.1 2.5e-57 194.1 0.1 1.3 1 0 0 1 1 1 1 Cation efflux family FGGY_C PF02782.11 EON98157.1 - 7.3e-26 91.0 0.0 1.7e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_3 PF07859.8 EON98157.1 - 2.7e-20 72.8 0.1 4.7e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EON98157.1 - 6.3e-17 61.2 0.0 9.8e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) FGGY_N PF00370.16 EON98157.1 - 1.3e-14 54.1 0.0 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain COesterase PF00135.23 EON98157.1 - 0.013 14.2 1.1 0.67 8.5 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family L31 PF09784.4 EON98158.1 - 1.8e-47 159.6 3.1 2e-47 159.5 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF3716 PF12511.3 EON98159.1 - 4.6e-07 29.3 0.0 8.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Filament PF00038.16 EON98160.1 - 0.0037 16.7 4.9 0.006 16.0 3.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 EON98160.1 - 0.28 10.7 5.9 0.55 9.8 4.1 1.4 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EON98160.1 - 0.42 10.2 6.9 0.89 9.1 4.8 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 EON98160.1 - 0.45 9.5 6.1 0.78 8.7 4.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4094 PF13334.1 EON98160.1 - 1.6 9.1 5.8 0.39 11.1 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) IBN_N PF03810.14 EON98161.1 - 1.7e-13 50.2 10.0 1.7e-12 47.0 0.1 4.5 5 0 0 5 5 5 1 Importin-beta N-terminal domain Cse1 PF08506.5 EON98161.1 - 2.5e-09 36.1 0.0 7.4e-09 34.6 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 EON98161.1 - 5.1e-08 32.9 1.6 4.5e-06 26.6 0.0 4.0 4 0 0 4 4 4 1 Exportin 1-like protein Vps35 PF03635.12 EON98161.1 - 0.0031 15.7 0.5 0.012 13.7 0.4 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF2435 PF10363.4 EON98161.1 - 0.023 14.5 0.2 0.083 12.7 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EON98161.1 - 0.039 14.3 0.6 4.4 7.7 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EON98161.1 - 0.08 12.7 1.1 0.39 10.5 0.1 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EON98161.1 - 0.096 12.8 0.5 0.75 10.0 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat YHS PF04945.8 EON98161.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 YHS domain IMS PF00817.15 EON98162.1 - 4.2e-32 111.0 0.0 1e-31 109.7 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EON98162.1 - 4.8e-12 45.9 0.0 9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EON98162.1 - 0.0065 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif PMT PF02366.13 EON98163.1 - 1.2e-74 250.7 17.7 1.2e-74 250.7 12.3 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EON98163.1 - 1.5e-56 190.9 0.0 2.3e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 MIR domain MtrH PF02007.13 EON98164.1 - 0.027 13.4 0.4 0.035 13.1 0.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Gamma-thionin PF00304.15 EON98164.1 - 2.1 8.4 8.6 3.9 7.5 6.0 1.5 1 1 0 1 1 1 0 Gamma-thionin family DIM PF08194.7 EON98164.1 - 3.7 7.5 7.6 0.87 9.5 0.5 3.0 3 0 0 3 3 3 0 DIM protein UCH PF00443.24 EON98165.1 - 2.4e-54 184.2 0.0 2.8e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EON98165.1 - 1.2e-17 64.3 0.0 3.2e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EON98165.1 - 1.9e-11 43.2 1.3 5e-11 41.8 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family PNP_UDP_1 PF01048.15 EON98166.1 - 0.00018 20.5 0.0 0.00035 19.6 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily PRP21_like_P PF12230.3 EON98167.1 - 7e-60 202.3 19.3 5.9e-59 199.3 13.4 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EON98167.1 - 6.9e-38 128.1 0.6 1.5e-18 66.1 0.1 3.2 3 0 0 3 3 3 2 Surp module Peptidase_S7 PF00949.16 EON98167.1 - 0.00036 19.9 0.1 0.00073 18.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.1 EON98167.1 - 0.053 13.4 0.6 0.33 10.9 0.4 2.4 2 1 0 2 2 2 0 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EON98167.1 - 0.064 11.5 0.7 0.49 8.6 0.0 2.2 1 1 1 2 2 2 0 Peptidase family S64 Peptidase_S3 PF00944.14 EON98167.1 - 0.072 12.5 0.2 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Alphavirus core protein Mito_carr PF00153.22 EON98168.1 - 3.4e-75 247.8 2.4 2.5e-26 91.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ART PF01129.13 EON98168.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase HMD PF03201.11 EON98168.1 - 0.043 13.7 0.0 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Sec2p PF06428.6 EON98170.1 - 3.8e-27 94.0 24.0 7.3e-27 93.1 12.0 2.5 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p FUSC PF04632.7 EON98170.1 - 0.62 8.4 4.8 0.89 7.9 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Methyltransf_23 PF13489.1 EON98171.1 - 3.9e-10 39.6 0.0 5.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98171.1 - 4.5e-05 23.8 0.3 0.00065 20.1 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98171.1 - 0.00023 21.7 0.2 0.0078 16.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98171.1 - 0.00033 20.2 0.0 0.84 9.2 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EON98171.1 - 0.0037 17.5 0.1 2 8.8 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EON98171.1 - 0.0042 17.5 0.1 0.12 12.8 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Oxidored_FMN PF00724.15 EON98171.1 - 0.0058 15.6 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ubie_methyltran PF01209.13 EON98171.1 - 0.0066 15.5 0.0 0.29 10.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family adh_short PF00106.20 EON98172.1 - 5.5e-25 88.2 4.6 1.1e-24 87.2 3.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98172.1 - 5.1e-12 45.8 2.3 2.3e-11 43.7 1.6 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON98172.1 - 1.8e-11 44.2 0.6 2.2e-11 44.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON98172.1 - 1.7e-05 24.3 0.4 1.9e-05 24.1 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EON98172.1 - 0.0033 16.3 0.1 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EON98172.1 - 0.0045 15.7 0.2 0.006 15.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LAP2alpha PF11560.3 EON98172.1 - 0.039 13.1 1.5 0.045 12.9 0.7 1.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Pectate_lyase_3 PF12708.2 EON98175.1 - 7.7e-24 85.0 17.2 8.1e-17 62.0 3.0 4.9 4 1 0 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 EON98175.1 - 0.026 13.9 0.0 0.1 12.0 0.0 2.1 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase ARPC4 PF05856.7 EON98177.1 - 5.2e-71 237.4 2.9 6.2e-71 237.2 2.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) AAA_10 PF12846.2 EON98178.1 - 2.2e-09 37.2 0.1 5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 EON98178.1 - 0.00096 19.0 0.2 0.0087 15.8 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF87 Zot PF05707.7 EON98178.1 - 0.0045 16.4 0.1 0.036 13.5 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) Zeta_toxin PF06414.7 EON98178.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EON98178.1 - 0.027 14.5 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.7 EON98178.1 - 0.053 11.8 0.0 0.17 10.1 0.0 1.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.13 EON98178.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_34 PF13872.1 EON98178.1 - 0.1 11.3 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 BSD PF03909.12 EON98180.1 - 0.0002 21.0 19.9 0.71 9.6 0.2 5.6 1 1 4 5 5 5 4 BSD domain Baculo_PEP_C PF04513.7 EON98180.1 - 0.063 13.1 8.6 1.6 8.5 0.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MHC_II_beta PF00969.14 EON98180.1 - 5.1 7.1 16.3 25 4.9 0.3 4.8 1 1 4 5 5 5 0 Class II histocompatibility antigen, beta domain ApoLp-III PF07464.6 EON98180.1 - 5.3 7.0 40.4 0.52 10.3 10.8 3.2 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Peptidase_C8 PF03569.8 EON98180.1 - 8.1 5.6 17.1 9.3 5.4 0.8 3.1 1 1 2 3 3 3 0 Peptidase family C8 E2_bind PF08825.5 EON98180.1 - 8.7 6.1 19.4 13 5.6 0.2 4.3 1 1 3 4 4 4 0 E2 binding domain TPX2 PF06886.6 EON98181.1 - 0.58 10.2 10.9 1.6 8.8 1.4 2.2 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF4574 PF15141.1 EON98181.1 - 7.1 6.4 8.1 0.38 10.5 1.9 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4574) Pkinase PF00069.20 EON98182.1 - 2.1e-55 187.7 0.0 3.1e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98182.1 - 3.6e-26 91.7 0.1 1.7e-25 89.5 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON98182.1 - 0.021 13.8 0.1 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like His_Phos_1 PF00300.17 EON98183.1 - 1.9e-27 96.3 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_S7 PF00949.16 EON98184.1 - 0.00054 19.3 0.1 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EON98184.1 - 0.028 13.7 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Trypsin_2 PF13365.1 EON98184.1 - 0.029 14.3 0.0 0.087 12.8 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 EON98184.1 - 0.12 11.2 0.0 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 PX PF00787.19 EON98185.1 - 1.4e-24 86.0 0.0 1.6e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 PX domain CBM_20 PF00686.14 EON98186.1 - 3.2e-16 58.7 0.3 6.4e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 Starch binding domain Response_reg PF00072.19 EON98187.1 - 2.6e-20 72.4 0.0 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF2000 PF09391.5 EON98187.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) RRM_6 PF14259.1 EON98188.1 - 1.2e-08 34.8 0.2 3.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1492 PF07374.6 EON98188.1 - 0.03 14.4 0.1 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) RRM_5 PF13893.1 EON98188.1 - 0.11 12.4 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COPI_C PF06957.6 EON98189.1 - 0.031 12.7 4.4 0.04 12.4 0.0 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus JAB PF01398.16 EON98190.1 - 8e-05 22.3 0.2 0.0013 18.4 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.22 EON98192.1 - 1.6e-46 155.9 8.6 5e-18 64.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0061 PF02696.9 EON98192.1 - 0.13 10.5 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family 2-Hacid_dh_C PF02826.14 EON98193.1 - 1.1e-54 184.3 0.0 1.5e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON98193.1 - 1.3e-21 76.4 0.0 1.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EON98193.1 - 8.7e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase PF05221.12 EON98194.1 - 2.5e-138 459.4 0.3 2.9e-138 459.2 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EON98194.1 - 2.9e-83 277.5 3.4 5e-83 276.8 2.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EON98194.1 - 3.6e-06 26.2 0.2 7.5e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EON98194.1 - 0.0081 15.7 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EON98194.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein IlvN PF07991.7 EON98194.1 - 0.038 13.3 0.4 0.069 12.5 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EON98194.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain RNA_Me_trans PF04252.8 EON98195.1 - 1.4e-27 96.3 0.0 7.5e-15 54.8 0.0 2.0 1 1 1 2 2 2 2 Predicted SAM-dependent RNA methyltransferase MARVEL PF01284.18 EON98196.1 - 3.4e-19 69.0 13.9 4.1e-19 68.8 9.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srx PF10328.4 EON98196.1 - 0.0015 17.6 0.3 0.0019 17.3 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2976 PF11190.3 EON98196.1 - 0.13 11.8 0.9 0.66 9.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF805 PF05656.9 EON98196.1 - 2.8 7.7 7.6 14 5.5 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF805) MRC1 PF09444.5 EON98197.1 - 3e-42 144.3 17.6 3e-42 144.3 12.2 7.7 7 4 0 7 7 7 1 MRC1-like domain APG5 PF04106.7 EON98198.1 - 7.8e-40 136.4 0.0 1.4e-39 135.6 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Apg5 Spc97_Spc98 PF04130.8 EON98199.1 - 3.4e-119 398.6 0.0 4.3e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 EON98199.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) APG17 PF04108.7 EON98199.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 SAGA-Tad1 PF12767.2 EON98200.1 - 2.9e-38 131.9 0.0 3.5e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GDH_N PF12466.3 EON98200.1 - 0.13 12.3 0.2 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 Glutamate dehydrogenase N terminal RGS PF00615.14 EON98202.1 - 0.00055 20.0 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain MFS_Mycoplasma PF07672.8 EON98202.1 - 0.0019 17.4 2.9 0.0019 17.4 2.0 1.7 2 0 0 2 2 2 1 Mycoplasma MFS transporter DHO_dh PF01180.16 EON98203.1 - 1.7e-20 73.1 0.0 2.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PFU PF09070.6 EON98204.1 - 2.1e-43 147.0 0.2 3.7e-43 146.2 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EON98204.1 - 5.8e-42 143.3 0.0 8.8e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EON98204.1 - 1.3e-37 126.3 16.1 4.7e-07 29.4 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EON98204.1 - 0.007 15.1 0.1 2.7 6.6 0.1 2.8 2 1 2 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 EON98204.1 - 0.012 15.3 0.0 1.5 8.6 0.0 3.4 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EON98204.1 - 0.17 12.2 1.7 1.4 9.2 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain HLH PF00010.21 EON98205.1 - 1.1e-17 63.4 0.0 1.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 EON98205.1 - 0.11 12.5 0.2 0.73 9.8 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family RseA_C PF03873.8 EON98205.1 - 0.12 12.2 2.9 0.24 11.3 1.2 2.1 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain bZIP_1 PF00170.16 EON98205.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.4 3 0 0 3 3 3 0 bZIP transcription factor Nnf1 PF03980.9 EON98205.1 - 5.4 7.0 5.3 4 7.4 0.1 2.3 1 1 0 2 2 2 0 Nnf1 WD40 PF00400.27 EON98206.1 - 2e-29 100.3 9.1 5.3e-11 41.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EON98206.1 - 0.015 14.0 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Amidase PF01425.16 EON98207.1 - 1.3e-29 103.4 0.1 1.9e-29 102.8 0.1 1.2 1 0 0 1 1 1 1 Amidase DUF1524 PF07510.6 EON98207.1 - 0.027 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) VWA_3 PF13768.1 EON98208.1 - 8.8e-28 96.9 0.0 1.8e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EON98208.1 - 6.6e-19 67.7 0.0 2.2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EON98208.1 - 1.2e-13 51.5 0.0 3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EON98208.1 - 9.3e-07 28.7 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EON98208.1 - 1.9e-05 24.0 0.0 4.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EON98208.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Mtr2 PF10429.4 EON98209.1 - 0.0046 16.7 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.2 EON98209.1 - 0.08 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Baculo_PEP_C PF04513.7 EON98210.1 - 0.0021 17.8 0.1 0.45 10.3 0.0 2.1 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EON98210.1 - 0.0033 17.6 2.8 0.35 11.1 2.0 2.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EON98210.1 - 0.0063 15.7 0.1 0.0091 15.2 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 EON98210.1 - 0.007 16.1 0.4 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EON98210.1 - 0.013 15.2 2.3 0.014 15.1 0.3 1.8 2 0 0 2 2 2 0 Laminin Domain II DUF4107 PF13389.1 EON98210.1 - 0.034 13.8 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) SOBP PF15279.1 EON98210.1 - 0.039 14.3 6.6 0.055 13.8 4.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein AATF-Che1 PF13339.1 EON98210.1 - 0.039 14.0 0.8 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3736 PF12540.3 EON98210.1 - 0.3 11.3 3.9 0.33 11.1 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) Abhydrolase_6 PF12697.2 EON98211.1 - 6e-19 68.8 0.2 7e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON98211.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON98211.1 - 0.11 11.9 0.0 5.8 6.4 0.0 2.6 2 1 1 3 3 3 0 alpha/beta hydrolase fold OPT PF03169.10 EON98212.1 - 9.4e-05 21.0 0.0 0.00012 20.7 0.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YfiO PF13525.1 EON98212.1 - 0.097 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein DUF2296 PF10058.4 EON98213.1 - 5.8e-19 67.5 0.1 1.1e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RanBP PF00641.13 EON98213.1 - 0.13 11.3 2.4 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others WD40 PF00400.27 EON98214.1 - 2.2e-17 62.1 4.1 0.002 17.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF605 PF04652.11 EON98214.1 - 0.12 11.7 23.5 0.26 10.6 4.8 2.2 2 0 0 2 2 2 0 Vta1 like TFIIF_alpha PF05793.7 EON98214.1 - 0.43 8.8 22.9 0.72 8.1 15.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sugar_tr PF00083.19 EON98216.1 - 7e-12 44.6 6.9 8e-12 44.4 4.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98216.1 - 4.3e-07 28.9 12.1 5.4e-07 28.6 8.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.1 EON98217.1 - 3.9e-24 85.9 0.5 9.7e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EON98217.1 - 1.2e-14 54.0 0.1 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98217.1 - 2.5e-07 30.4 0.3 3.9e-05 23.3 0.0 2.6 1 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain SRR1 PF07985.7 EON98218.1 - 1.3e-05 24.9 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 SRR1 VCBS PF13517.1 EON98220.1 - 1.3e-12 47.8 19.7 1.2e-09 38.4 3.2 5.1 4 2 1 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 EON98220.1 - 3.2e-12 46.9 2.1 4.6e-12 46.4 0.8 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EON98220.1 - 5.7e-08 32.8 0.9 6.2e-07 29.4 0.2 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Aerolysin PF01117.15 EON98220.1 - 0.007 15.3 0.1 0.021 13.7 0.0 1.8 2 0 0 2 2 2 1 Aerolysin toxin FG-GAP PF01839.18 EON98220.1 - 0.0085 15.7 28.9 0.075 12.7 3.0 4.9 5 0 0 5 5 5 3 FG-GAP repeat TcdB_toxin_midN PF12256.3 EON98220.1 - 0.4 10.1 5.6 0.82 9.0 0.2 3.1 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region AAA_12 PF13087.1 EON98222.1 - 7.2e-37 126.7 0.0 1.4e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EON98222.1 - 5e-28 98.2 0.1 1.2e-27 96.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EON98222.1 - 2.8e-09 36.8 0.1 7.3e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EON98222.1 - 1.8e-08 34.0 0.2 4.1e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EON98222.1 - 0.00071 19.1 0.0 0.26 10.7 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EON98222.1 - 0.0042 16.3 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EON98222.1 - 0.088 11.7 0.1 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EON98222.1 - 0.092 12.0 1.8 0.24 10.6 0.1 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EON98222.1 - 0.098 12.7 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain FLO_LFY PF01698.11 EON98223.1 - 1.7 7.3 8.0 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF1993 PF09351.5 EON98224.1 - 3.9e-47 160.1 0.0 4.4e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MFS_1 PF07690.11 EON98225.1 - 1.8e-30 105.8 25.4 1.8e-30 105.8 17.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 EON98225.1 - 0.084 12.9 0.1 0.084 12.9 0.1 4.6 4 1 1 5 5 5 0 2TM domain zf-RING_2 PF13639.1 EON98227.1 - 2.3e-09 36.9 3.9 2.3e-09 36.9 2.7 2.6 2 1 1 3 3 3 1 Ring finger domain FANCL_C PF11793.3 EON98227.1 - 0.00096 19.0 3.8 0.00096 19.0 2.6 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 EON98227.1 - 0.0014 18.3 5.2 0.003 17.2 3.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EON98227.1 - 0.0034 17.3 4.9 0.0034 17.3 3.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EON98227.1 - 0.0038 16.9 4.5 0.0038 16.9 3.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EON98227.1 - 0.0042 16.6 5.4 0.0042 16.6 3.7 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EON98227.1 - 0.0071 16.4 4.2 0.0071 16.4 2.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EON98227.1 - 0.0086 15.8 1.7 0.0086 15.8 1.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EON98227.1 - 0.017 14.7 2.7 0.017 14.7 1.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EON98227.1 - 0.021 14.8 6.4 0.051 13.6 4.4 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EON98227.1 - 0.03 14.0 1.6 0.078 12.7 1.1 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.1 EON98227.1 - 3 7.6 9.0 0.11 12.1 0.9 2.4 2 0 0 2 2 2 0 RING-type zinc-finger GRIP PF01465.15 EON98228.1 - 2.9e-15 55.5 0.0 6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EON98228.1 - 3.1e-05 23.6 164.0 4.5e-05 23.1 16.8 8.9 3 2 6 9 9 8 5 IncA protein GAS PF13851.1 EON98228.1 - 7.8e-05 21.9 142.4 0.015 14.5 7.6 8.8 3 2 7 10 10 10 5 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EON98228.1 - 0.00028 20.6 18.7 0.00028 20.6 13.0 8.9 3 2 5 8 8 8 2 TPR/MLP1/MLP2-like protein DUF4201 PF13870.1 EON98228.1 - 0.00076 18.9 0.2 0.00076 18.9 0.1 9.8 3 2 6 9 9 8 1 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 EON98228.1 - 0.0008 19.2 160.2 0.005 16.6 11.0 9.9 3 2 6 9 9 8 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 EON98228.1 - 0.0011 18.4 7.8 0.0011 18.4 5.4 10.8 3 2 8 11 11 9 3 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EON98228.1 - 0.0013 18.4 4.4 0.0013 18.4 3.0 14.4 5 2 10 16 16 14 2 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EON98228.1 - 0.003 16.2 16.7 0.003 16.2 11.6 8.4 3 2 3 7 7 7 2 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EON98228.1 - 0.01 13.5 159.4 0.0071 14.1 17.3 5.1 3 1 0 4 4 4 0 Myosin tail MscS_porin PF12795.2 EON98228.1 - 0.011 15.1 0.6 0.011 15.1 0.4 8.3 4 2 4 8 8 7 0 Mechanosensitive ion channel porin domain DUF869 PF05911.6 EON98228.1 - 0.011 14.0 116.3 0.021 13.1 9.5 5.5 3 2 2 5 5 5 0 Plant protein of unknown function (DUF869) DivIC PF04977.10 EON98228.1 - 0.019 14.4 0.6 0.019 14.4 0.4 14.7 7 4 10 17 17 16 0 Septum formation initiator Filament PF00038.16 EON98228.1 - 0.031 13.7 139.5 0.19 11.1 25.7 8.8 3 2 5 8 8 8 0 Intermediate filament protein Bap31 PF05529.7 EON98228.1 - 0.18 11.2 0.0 0.18 11.2 0.0 10.9 3 2 5 9 9 7 0 B-cell receptor-associated protein 31-like Reo_sigmaC PF04582.7 EON98228.1 - 0.36 9.9 58.1 0.29 10.2 7.1 6.6 2 2 3 7 7 7 0 Reovirus sigma C capsid protein MerR-DNA-bind PF09278.6 EON98228.1 - 0.42 11.0 0.0 0.42 11.0 0.0 13.0 10 3 5 15 15 12 0 MerR, DNA binding TBPIP PF07106.8 EON98228.1 - 3.2 7.2 126.8 0.09 12.3 3.1 11.7 3 2 9 12 12 12 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EON98228.1 - 4.6 7.3 86.6 0.15 12.1 7.5 9.2 3 2 6 10 10 10 0 Fibrinogen alpha/beta chain family WD40_alt PF14077.1 EON98228.1 - 6.1 6.5 14.9 4.7 6.9 0.4 5.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif AAA_13 PF13166.1 EON98228.1 - 6.2 5.1 116.1 0.16 10.3 16.5 6.0 1 1 3 4 4 4 0 AAA domain Glyco_hydro_17 PF00332.13 EON98229.1 - 1.6e-11 43.7 2.0 9.3e-07 28.1 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Cellulase PF00150.13 EON98230.1 - 3.4e-53 180.6 1.4 4.2e-53 180.3 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EON98230.1 - 2.5e-13 49.4 17.1 2.5e-13 49.4 11.9 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF1479 PF07350.7 EON98231.1 - 4.5e-148 493.1 0.0 5.5e-148 492.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) TPP_enzyme_M PF00205.17 EON98234.1 - 1.4e-21 76.7 0.0 3.8e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EON98234.1 - 2e-21 76.1 0.0 3.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EON98234.1 - 6.1e-12 45.3 0.0 2.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GCD14_N PF14801.1 EON98235.1 - 0.17 11.4 1.4 0.21 11.1 0.6 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Glyco_hyd_65N_2 PF14498.1 EON98236.1 - 6.4e-27 94.7 0.2 3.8e-21 75.8 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain VCBS PF13517.1 EON98237.1 - 1.7e-17 63.5 46.9 2e-09 37.6 2.2 7.5 4 2 3 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EON98237.1 - 0.00033 20.1 11.0 0.55 9.6 0.2 5.0 3 1 1 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.18 EON98237.1 - 0.0026 17.4 1.9 0.0026 17.4 1.3 7.4 6 1 0 6 6 6 3 FG-GAP repeat DUF1880 PF08976.6 EON98237.1 - 0.0076 16.3 0.3 0.021 14.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1880) RIO1 PF01163.17 EON98238.1 - 4.8e-69 231.4 1.0 6.1e-69 231.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EON98238.1 - 0.0082 15.9 0.2 4.3 6.9 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EON98238.1 - 0.022 13.8 0.1 0.75 8.8 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EON98238.1 - 1.8 7.6 5.7 0.46 9.5 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain Glyco_hydro_1 PF00232.13 EON98239.1 - 6.2e-143 476.2 3.1 7.4e-143 476.0 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 VIT1 PF01988.14 EON98240.1 - 3.9e-40 137.6 0.1 5.7e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 VIT family ATPase_gene1 PF09527.5 EON98240.1 - 8.7 6.2 11.0 24 4.8 5.5 2.5 1 1 1 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Beta-lactamase PF00144.19 EON98241.1 - 7.4e-49 166.5 0.1 1e-48 166.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EON98241.1 - 0.085 12.1 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.17 EON98242.1 - 0.00021 19.9 0.0 0.00023 19.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.6 EON98244.1 - 3.6e-22 78.9 0.1 7.5e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EON98244.1 - 0.00012 21.2 0.0 0.0003 20.0 0.0 1.4 1 1 0 1 1 1 1 Subtilase family AAA_16 PF13191.1 EON98245.1 - 0.00027 20.9 1.7 0.013 15.5 0.0 4.0 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.7 EON98245.1 - 0.00027 20.6 0.3 0.0017 18.0 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EON98245.1 - 0.0012 18.9 0.1 0.056 13.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EON98245.1 - 0.0016 18.5 0.0 0.0049 17.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TPR_11 PF13414.1 EON98245.1 - 0.021 14.4 1.1 3.5 7.3 0.1 3.3 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EON98245.1 - 0.022 14.6 3.3 35 4.6 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat NTPase_1 PF03266.10 EON98245.1 - 0.033 13.9 0.0 0.097 12.3 0.0 1.8 1 0 0 1 1 1 0 NTPase TPR_12 PF13424.1 EON98245.1 - 0.11 12.4 6.0 1 9.3 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA_10 PF12846.2 EON98245.1 - 0.6 9.4 5.9 7.2 5.9 0.0 3.9 5 0 0 5 5 5 0 AAA-like domain DUF4215 PF13948.1 EON98246.1 - 0.0045 17.1 2.3 0.0067 16.6 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) Med13_C PF06333.7 EON98246.1 - 0.11 10.9 2.3 0.13 10.7 1.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Macoilin PF09726.4 EON98246.1 - 8.2 4.5 10.0 9.7 4.3 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DASH_Dad4 PF08650.5 EON98247.1 - 0.046 13.6 3.3 0.085 12.7 0.0 2.6 3 1 0 3 3 3 0 DASH complex subunit Dad4 CBM_21 PF03370.8 EON98248.1 - 3e-36 123.8 0.3 6.2e-36 122.8 0.2 1.5 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Tyrosinase PF00264.15 EON98249.1 - 2.7e-51 174.8 2.1 3.6e-51 174.4 1.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase APG17 PF04108.7 EON98250.1 - 9.8e-103 344.1 3.1 1.3e-102 343.7 2.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Bacillus_HBL PF05791.6 EON98250.1 - 0.00021 20.6 2.5 0.48 9.7 0.1 3.2 3 0 0 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) DUF4358 PF14270.1 EON98250.1 - 0.038 13.8 0.7 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Rabaptin PF03528.10 EON98250.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.1 2 1 0 2 2 2 0 Rabaptin Prominin PF05478.6 EON98250.1 - 0.19 9.2 3.7 1.7 6.1 0.1 2.1 2 0 0 2 2 2 0 Prominin Occludin_ELL PF07303.8 EON98250.1 - 0.23 12.1 2.3 2.3 8.9 0.0 3.1 2 1 1 3 3 3 0 Occludin homology domain IncA PF04156.9 EON98250.1 - 0.26 10.8 7.8 0.38 10.3 0.0 2.6 3 0 0 3 3 3 0 IncA protein FadA PF09403.5 EON98250.1 - 0.9 9.5 5.6 25 4.9 0.0 3.3 2 1 0 2 2 2 0 Adhesion protein FadA CorA PF01544.13 EON98250.1 - 2.1 7.3 5.4 8 5.3 0.9 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DivIVA PF05103.8 EON98250.1 - 8 6.5 7.8 6.8 6.7 1.0 3.1 4 0 0 4 4 4 0 DivIVA protein Peptidase_M24 PF00557.19 EON98251.1 - 1.1e-55 188.4 0.1 1.5e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EON98251.1 - 2.7e-25 88.3 0.0 5.5e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HET PF06985.6 EON98253.1 - 0.00049 20.2 1.8 0.0065 16.6 1.6 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.14 EON98254.1 - 1e-157 524.7 0.3 1.3e-157 524.4 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EON98254.1 - 5.8e-19 67.7 0.0 1.3e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EON98254.1 - 2.4e-09 36.8 0.0 4.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family AA_permease PF00324.16 EON98255.1 - 1.9e-106 356.3 40.4 2.4e-106 355.9 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON98255.1 - 5.6e-32 110.8 45.9 7.6e-32 110.3 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M14 PF00246.19 EON98256.1 - 1.2e-76 258.0 0.1 1.4e-76 257.7 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Aft1_HRA PF11786.3 EON98256.1 - 0.04 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Aft1 HRA domain Lipase_3 PF01764.20 EON98256.1 - 0.065 12.8 0.2 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) MFS_1 PF07690.11 EON98258.1 - 3e-45 154.4 38.7 3e-45 154.4 26.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON98258.1 - 1.3e-15 56.6 10.3 1.3e-15 56.6 7.2 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_OmpA PF13436.1 EON98259.1 - 0.26 10.9 7.4 0.47 10.1 5.1 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain TraT PF05818.7 EON98259.1 - 0.43 9.9 3.2 0.71 9.2 2.2 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GMC_oxred_N PF00732.14 EON98260.1 - 6.3e-58 196.2 0.0 8.1e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON98260.1 - 7.4e-31 107.3 0.0 2.4e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON98260.1 - 9.1e-07 28.0 0.2 0.00055 18.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EON98260.1 - 1.9e-05 24.6 0.1 0.00035 20.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON98260.1 - 3.2e-05 23.0 0.1 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EON98260.1 - 3.8e-05 22.7 0.1 0.0021 17.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON98260.1 - 0.0002 21.3 0.5 0.00093 19.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EON98260.1 - 0.0012 17.4 0.6 0.019 13.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EON98260.1 - 0.013 14.6 0.7 0.023 13.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EON98260.1 - 0.036 13.1 0.0 0.082 11.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EON98260.1 - 0.062 13.2 0.1 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 EON98260.1 - 0.1 12.6 0.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON98260.1 - 0.19 10.6 0.0 0.85 8.4 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclin PF08613.6 EON98261.1 - 5.6e-38 130.6 0.0 7.3e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Tymo_45kd_70kd PF03251.8 EON98262.1 - 0.098 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein XFP_N PF09364.5 EON98263.1 - 3e-121 404.5 0.0 3.8e-121 404.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EON98263.1 - 9.5e-69 230.5 0.0 1.6e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EON98263.1 - 4.2e-66 222.2 0.0 7.1e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EON98263.1 - 0.00033 20.2 0.3 0.0029 17.1 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidase PF01425.16 EON98264.1 - 3.3e-43 148.1 0.1 1.6e-16 60.2 0.0 3.1 1 1 2 3 3 3 3 Amidase Ank_2 PF12796.2 EON98265.1 - 1.5e-27 95.7 3.0 3e-10 40.3 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EON98265.1 - 1.4e-22 78.2 2.2 4.6e-05 23.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EON98265.1 - 3e-15 56.2 1.8 2.6e-05 24.6 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON98265.1 - 9.1e-15 54.3 0.6 0.00071 19.7 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON98265.1 - 3.7e-14 51.4 1.0 0.0072 16.4 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeat DUF924 PF06041.6 EON98266.1 - 5.2e-52 176.3 0.0 8e-52 175.7 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SnoaL_2 PF12680.2 EON98267.1 - 0.00039 20.7 0.0 0.00048 20.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain UDPGT PF00201.13 EON98269.1 - 2.7e-15 55.9 0.0 4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase E1-E2_ATPase PF00122.15 EON98270.1 - 2.4e-57 193.6 0.6 2.4e-57 193.6 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EON98270.1 - 6.6e-47 159.3 9.0 6.6e-47 159.3 6.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EON98270.1 - 5.5e-31 108.6 0.0 1.9e-30 106.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EON98270.1 - 1.9e-16 59.7 0.0 4.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EON98270.1 - 6e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EON98270.1 - 2.1e-11 43.1 0.1 1e-09 37.7 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EON98270.1 - 3.8e-05 23.3 0.3 0.00035 20.2 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EON98270.1 - 0.089 12.7 0.0 0.089 12.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) FAD_binding_4 PF01565.18 EON98271.1 - 5.5e-17 61.5 1.7 1.2e-16 60.4 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON98271.1 - 4.2e-12 45.7 0.1 6.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Pectate_lyase PF03211.8 EON98272.1 - 7.8e-80 267.2 7.7 9.3e-80 267.0 5.3 1.0 1 0 0 1 1 1 1 Pectate lyase HATPase_c PF02518.21 EON98273.1 - 1.7e-19 69.5 0.0 3.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EON98273.1 - 1.1e-15 57.5 0.0 3.4e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EON98273.1 - 1.5e-12 47.3 2.2 2.6e-12 46.5 0.3 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EON98273.1 - 6.9e-05 22.9 0.0 0.00051 20.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 EON98273.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 GAF domain Ferritin_2 PF13668.1 EON98274.1 - 1.6e-16 60.4 0.0 1.3e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Ferritin-like domain SET PF00856.23 EON98275.1 - 1.2e-08 35.4 0.0 2.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 SET domain adh_short PF00106.20 EON98276.1 - 8.5e-08 32.2 2.6 1.3e-07 31.6 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98276.1 - 1.8e-05 24.6 0.0 0.00013 21.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lon_C PF05362.8 EON98276.1 - 0.05 12.8 0.1 0.078 12.2 0.1 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain Transp_cyt_pur PF02133.10 EON98277.1 - 5e-114 381.2 36.8 5.7e-114 381.0 25.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Hydantoinase_B PF02538.9 EON98278.1 - 9.4e-39 133.0 4.1 1.1e-38 132.8 2.8 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Methyltransf_18 PF12847.2 EON98279.1 - 8.8e-11 42.3 0.0 1.4e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98279.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98279.1 - 1.8e-07 31.5 0.0 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98279.1 - 1.2e-06 28.8 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98279.1 - 1.7e-06 27.6 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON98279.1 - 9.2e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON98279.1 - 1e-05 24.8 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EON98279.1 - 5.9e-05 23.0 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON98279.1 - 0.0018 17.6 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EON98279.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Cons_hypoth95 PF03602.10 EON98279.1 - 0.041 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NodS PF05401.6 EON98279.1 - 0.057 12.8 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 EON98279.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family PAT1 PF09770.4 EON98281.1 - 9.1 4.3 26.8 13 3.8 18.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HlyD PF00529.15 EON98283.1 - 0.051 12.8 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein SBP_bac_8 PF13416.1 EON98284.1 - 0.13 11.9 0.4 0.28 10.8 0.2 1.4 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein PG_binding_1 PF01471.13 EON98285.1 - 3.3e-09 36.5 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.5 EON98285.1 - 0.00034 20.5 0.1 0.03 14.2 0.1 2.2 1 1 0 1 1 1 1 Predicted Peptidoglycan domain Aldo_ket_red PF00248.16 EON98286.1 - 1.2e-52 178.4 0.0 1.4e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BBE PF08031.7 EON98287.1 - 2e-13 50.0 0.4 2e-13 50.0 0.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like Transferase PF02458.10 EON98288.1 - 2.9e-13 49.0 0.0 6.5e-09 34.7 0.0 2.9 3 0 0 3 3 3 3 Transferase family Cu_amine_oxid PF01179.15 EON98289.1 - 3.4e-75 253.3 2.0 5.3e-75 252.6 1.4 1.3 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cupin_2 PF07883.6 EON98290.1 - 4.6e-16 58.0 0.6 8.1e-16 57.2 0.4 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EON98290.1 - 3.2e-08 33.3 0.1 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EON98290.1 - 3.7e-06 26.4 0.2 6.9e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EON98290.1 - 0.00066 19.3 0.1 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 Cupin CENP-C_C PF11699.3 EON98290.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like EutQ PF06249.7 EON98290.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Oxidored_FMN PF00724.15 EON98291.1 - 3.5e-69 233.3 0.0 4.5e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AA_permease PF00324.16 EON98292.1 - 6e-140 466.7 37.4 7.8e-140 466.3 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON98292.1 - 5.6e-42 143.7 39.9 7.4e-42 143.3 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 EON98293.1 - 1.2e-05 24.3 0.0 2.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C33 PF05412.7 EON98293.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Glyco_hydro_30 PF02055.11 EON98294.1 - 1.1e-51 175.6 6.2 1.5e-51 175.1 4.3 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EON98294.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF1446 PF07287.6 EON98296.1 - 9.4e-123 409.2 0.4 1.1e-122 408.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) tRNA-synt_2b PF00587.20 EON98297.1 - 5.1e-49 166.1 0.0 6.8e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EON98297.1 - 2.4e-07 30.5 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Ada3 PF10198.4 EON98298.1 - 3e-44 149.9 0.0 4.5e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF1772 PF08592.6 EON98299.1 - 1.7e-22 79.6 1.0 2.7e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Utp11 PF03998.8 EON98300.1 - 3.6e-57 193.9 19.2 4.2e-57 193.7 13.3 1.1 1 0 0 1 1 1 1 Utp11 protein Spt5_N PF11942.3 EON98300.1 - 1.5 9.5 28.8 0.1 13.2 3.0 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Sigma70_ner PF04546.8 EON98300.1 - 3 7.3 21.5 0.21 11.1 5.5 2.3 1 1 1 2 2 2 0 Sigma-70, non-essential region VPS28 PF03997.7 EON98301.1 - 7.9e-56 188.6 0.1 9e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EON98301.1 - 0.056 13.2 3.5 0.52 10.1 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein G HMG_box PF00505.14 EON98303.1 - 2.7e-08 33.9 0.1 6.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EON98303.1 - 1.5e-05 25.2 0.8 4.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 HMG-box domain Maf PF02545.9 EON98305.1 - 1.5e-44 151.4 0.0 2.3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein Pal1 PF08316.6 EON98306.1 - 6.9e-11 42.7 0.8 5.2e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein LNS2 PF08235.8 EON98307.1 - 1.9e-70 235.4 0.0 3.1e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EON98307.1 - 2.7e-39 133.2 0.0 6e-39 132.1 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EON98307.1 - 0.014 14.7 0.0 0.69 9.2 0.0 2.8 4 0 0 4 4 4 0 HAD superfamily, subfamily IIIB (Acid phosphatase) IFT57 PF10498.4 EON98307.1 - 0.88 8.2 5.3 1.4 7.5 3.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AF1Q PF15017.1 EON98307.1 - 3.8 7.4 13.5 0.14 12.0 0.3 2.6 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator ubiquitin PF00240.18 EON98308.1 - 8.3e-19 66.7 0.0 1.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EON98308.1 - 2.9e-08 33.3 0.0 8.3e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EON98308.1 - 1.5e-06 27.7 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EON98308.1 - 8.3e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RicinB_lectin_2 PF14200.1 EON98308.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like CKS PF01111.14 EON98310.1 - 6.6e-33 112.3 2.2 1e-32 111.7 1.5 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit zf-CCCH PF00642.19 EON98311.1 - 9.3e-25 85.7 32.5 8.2e-07 28.5 0.2 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EON98311.1 - 0.022 14.7 0.2 0.022 14.7 0.2 5.5 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type GRP PF07172.6 EON98311.1 - 0.9 10.0 16.5 0.36 11.3 9.3 1.8 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.27 EON98312.1 - 1.9e-12 46.5 5.4 3.9e-05 23.3 0.5 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 EON98312.1 - 3.5e-05 23.5 0.0 0.083 12.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EON98312.1 - 0.051 13.0 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain MFS_1 PF07690.11 EON98313.1 - 5.4e-15 54.9 32.2 5.4e-15 54.9 22.3 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON98313.1 - 2.5e-10 39.1 7.7 8e-10 37.5 5.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIID-31kDa PF02291.10 EON98314.1 - 7.1e-23 80.7 0.0 5.1e-22 78.0 0.0 2.0 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit fn3 PF00041.16 EON98315.1 - 5.7e-07 29.5 0.2 2.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain DAO PF01266.19 EON98316.1 - 5.6e-21 74.8 0.0 7.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON98316.1 - 1.4e-06 28.5 0.1 4.6e-06 26.9 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON98316.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON98316.1 - 0.00031 19.7 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EON98316.1 - 0.0029 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EON98316.1 - 0.0031 17.4 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EON98316.1 - 0.0034 16.4 0.1 0.0052 15.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EON98316.1 - 0.0073 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.17 EON98316.1 - 0.0084 15.0 0.1 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EON98316.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EON98316.1 - 0.02 14.5 0.3 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EON98316.1 - 0.025 13.9 0.3 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 EON98316.1 - 0.035 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON98316.1 - 0.046 12.2 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Rho_RNA_bind PF07497.7 EON98316.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Fcf2 PF08698.6 EON98316.1 - 0.13 12.2 0.1 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing 2-Hacid_dh_C PF02826.14 EON98316.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1b PF00579.20 EON98317.1 - 1.2e-56 191.9 0.0 1.5e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Noc2 PF03715.8 EON98318.1 - 2.2e-119 397.7 0.0 4e-119 396.9 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Spc7 PF08317.6 EON98319.1 - 0.0049 15.5 10.8 0.071 11.7 2.5 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF1366 PF07104.6 EON98319.1 - 6.1 6.5 13.2 0.35 10.5 2.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1366) Syntaxin-6_N PF09177.6 EON98319.1 - 6.6 7.2 6.8 9.2 6.7 1.2 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HVSL PF09749.4 EON98320.1 - 9.4e-68 227.7 0.0 1.1e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EON98320.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Pribosyltran PF00156.22 EON98321.1 - 3e-16 59.2 0.0 4.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EON98321.1 - 0.0061 15.7 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Amidohydro_1 PF01979.15 EON98322.1 - 1.5e-61 208.8 1.3 2.4e-61 208.2 0.9 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EON98322.1 - 6.8e-54 181.1 4.0 1.3e-53 180.2 1.0 2.3 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EON98322.1 - 4e-42 142.1 0.3 6.7e-42 141.3 0.2 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EON98322.1 - 2.3e-21 75.6 0.0 9.7e-21 73.6 0.0 2.1 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EON98322.1 - 4.4e-07 29.6 3.9 1.5e-06 27.9 2.7 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EON98322.1 - 0.0011 18.2 0.8 0.012 14.8 0.0 2.4 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EON98322.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Redoxin PF08534.5 EON98323.1 - 0.033 13.7 0.0 0.15 11.5 0.0 1.9 1 1 1 2 2 2 0 Redoxin Pyr_redox_2 PF07992.9 EON98324.1 - 1.2e-28 100.3 0.0 2.3e-28 99.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON98324.1 - 2.2e-19 69.6 1.9 2.7e-17 62.9 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON98324.1 - 2.4e-09 37.5 0.1 3.2e-06 27.3 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON98324.1 - 7.1e-06 25.1 0.4 0.2 10.5 0.1 3.3 2 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON98324.1 - 1.3e-05 25.0 0.2 0.01 15.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EON98324.1 - 1.5e-05 25.1 0.1 0.0059 16.8 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EON98324.1 - 6.3e-05 22.1 0.6 0.00052 19.1 0.0 2.4 2 1 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EON98324.1 - 0.00015 20.9 1.1 2.1 7.3 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain Shikimate_DH PF01488.15 EON98324.1 - 0.00034 20.7 0.3 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EON98324.1 - 0.0016 17.3 5.3 0.28 9.9 0.2 3.9 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EON98324.1 - 0.0019 17.3 0.1 0.051 12.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EON98324.1 - 0.0031 16.4 5.2 0.15 10.8 0.2 3.1 3 1 0 4 4 4 2 FAD binding domain K_oxygenase PF13434.1 EON98324.1 - 0.0063 15.4 0.1 0.36 9.7 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EON98324.1 - 0.031 12.7 1.1 1.9 6.8 0.1 3.1 2 1 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 EON98324.1 - 0.098 11.2 0.2 0.36 9.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ERO1 PF04137.10 EON98325.1 - 2.8e-137 457.5 0.0 3.6e-137 457.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) MFS_1_like PF12832.2 EON98326.1 - 1.2e-17 63.4 0.3 6.2e-17 61.1 0.2 2.3 1 1 0 1 1 1 1 MFS_1 like family Cytochrom_B558a PF05038.8 EON98326.1 - 0.0033 17.0 0.1 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Glyco_hydro_45 PF02015.11 EON98327.1 - 2.9e-88 295.1 20.5 3.5e-88 294.9 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NAD_binding_10 PF13460.1 EON98328.1 - 1.5e-05 25.1 1.1 2.2e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EON98328.1 - 0.0032 17.0 1.0 0.0063 16.0 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EON98328.1 - 0.016 15.3 0.3 0.052 13.6 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EON98328.1 - 0.036 13.7 0.6 0.054 13.1 0.4 1.2 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EON98328.1 - 0.048 13.5 2.3 0.082 12.8 1.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase CybS PF05328.7 EON98329.1 - 4.8e-52 175.0 0.0 6.1e-52 174.7 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EON98329.1 - 0.00037 20.3 0.5 0.0033 17.2 0.3 2.0 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HLH PF00010.21 EON98330.1 - 1.6e-07 30.9 0.0 3.3e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rab5-bind PF09311.6 EON98330.1 - 0.017 14.9 1.7 0.02 14.7 1.2 1.1 1 0 0 1 1 1 0 Rabaptin-like protein Vasculin PF15337.1 EON98330.1 - 0.02 15.3 0.2 0.033 14.6 0.1 1.4 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Myb_CC_LHEQLE PF14379.1 EON98330.1 - 0.55 9.8 5.0 0.17 11.4 0.4 2.0 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Cmc1 PF08583.5 EON98332.1 - 1.4e-12 47.1 0.3 1.4e-12 47.1 0.2 2.8 4 0 0 4 4 4 1 Cytochrome c oxidase biogenesis protein Cmc1 like Protocadherin PF08374.6 EON98332.1 - 0.019 14.6 1.4 0.028 14.0 1.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF501 PF04417.7 EON98332.1 - 1.8 8.3 6.0 6 6.7 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF501) HSP70 PF00012.15 EON98333.1 - 2.9e-234 778.5 8.3 3.2e-234 778.3 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EON98333.1 - 7.8e-18 64.1 0.4 8.6e-17 60.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EON98333.1 - 0.00052 19.6 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EON98333.1 - 0.021 13.6 0.2 0.15 10.8 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 EON98333.1 - 0.072 12.9 2.3 7.8 6.3 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA DUF2404 PF10296.4 EON98334.1 - 0.00027 21.0 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF3419 PF11899.3 EON98336.1 - 3.7e-158 526.2 0.0 5.3e-158 525.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EON98336.1 - 4e-16 59.1 0.0 1.9e-14 53.7 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98336.1 - 7.3e-11 41.8 0.0 7.7e-10 38.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98336.1 - 1.7e-09 38.0 0.0 5.9e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98336.1 - 1.3e-08 35.4 0.0 5.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON98336.1 - 2.8e-07 30.5 0.0 9e-06 25.7 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98336.1 - 3.9e-06 27.2 0.0 0.0026 18.2 0.0 4.0 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON98336.1 - 8.4e-06 25.0 0.0 0.00075 18.6 0.0 2.7 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EON98336.1 - 8.3e-05 22.8 0.0 0.00022 21.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EON98336.1 - 0.00091 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 EON98336.1 - 0.0056 16.1 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EON98336.1 - 0.015 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EON98336.1 - 0.035 13.1 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase PIP5K PF01504.13 EON98337.1 - 6.7e-60 202.3 0.1 1.7e-59 200.9 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EON98337.1 - 5.5e-20 71.4 0.1 8e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aldedh PF00171.17 EON98338.1 - 9.1e-69 231.9 0.0 1e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Bromodomain PF00439.20 EON98339.1 - 1.6e-35 120.8 1.0 2.7e-18 65.6 0.2 2.5 2 0 0 2 2 2 2 Bromodomain Nop14 PF04147.7 EON98339.1 - 0.086 10.7 8.0 0.11 10.3 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EON98339.1 - 1.7 8.1 11.8 4.2 6.8 8.2 1.6 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 EON98339.1 - 1.8 6.9 12.2 2.5 6.4 8.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EON98339.1 - 3.2 5.6 8.5 4.7 5.1 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EON98339.1 - 3.2 6.9 7.1 5.8 6.0 4.9 1.4 1 0 0 1 1 1 0 NOA36 protein IBN_N PF03810.14 EON98340.1 - 5.4e-14 51.8 0.4 1.6e-12 47.1 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EON98340.1 - 0.00012 22.0 1.4 0.00097 19.0 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HET PF06985.6 EON98341.1 - 1e-28 100.2 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1930 PF09122.5 EON98341.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) Histidinol_dh PF00815.15 EON98342.1 - 1.2e-151 505.0 5.3 1.7e-151 504.5 3.7 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EON98342.1 - 6.3e-26 89.8 0.1 1.2e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EON98342.1 - 1.7e-10 40.9 1.8 5e-10 39.5 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_hydro_47 PF01532.15 EON98344.1 - 1.1e-100 337.4 0.0 1.9e-100 336.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 T_cell_tran_alt PF15128.1 EON98346.1 - 5.8 6.4 9.1 8.6 5.8 0.6 2.1 1 1 1 2 2 2 0 T-cell leukemia translocation-altered adh_short_C2 PF13561.1 EON98347.1 - 2.7e-28 99.3 0.0 3.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON98347.1 - 2.7e-23 82.7 1.9 3.4e-23 82.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98347.1 - 1.2e-09 38.0 0.1 1.6e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.20 EON98347.1 - 0.0064 15.7 0.3 0.0078 15.4 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EON98347.1 - 0.047 13.2 0.8 1.1 8.7 0.2 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 EON98348.1 - 1.6e-112 375.5 0.0 2.2e-112 375.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ING PF12998.2 EON98348.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RNA_pol_Rpb1_1 PF04997.7 EON98349.1 - 3.7e-111 371.6 0.0 6.6e-111 370.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EON98349.1 - 3e-100 335.0 0.0 5.7e-100 334.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EON98349.1 - 3.7e-70 235.1 0.0 7.8e-70 234.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EON98349.1 - 5.6e-56 189.2 0.6 1.1e-55 188.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EON98349.1 - 1.3e-48 164.7 0.0 3.1e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EON98349.1 - 1.4e-43 147.8 8.5 3.9e-43 146.4 5.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EON98349.1 - 1.1e-36 124.8 0.0 2.4e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 F-box PF00646.28 EON98350.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EON98350.1 - 0.11 12.5 0.1 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain NPR2 PF06218.6 EON98351.1 - 5.6e-121 404.2 0.2 1.1e-102 343.9 0.1 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Het-C PF07217.6 EON98353.1 - 5.5e-269 893.4 0.1 7.1e-269 893.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Methyltransf_31 PF13847.1 EON98354.1 - 2.7e-09 36.7 0.0 4.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98354.1 - 5.4e-09 36.4 0.0 2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98354.1 - 3e-07 30.8 0.0 5.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98354.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON98354.1 - 0.00013 22.2 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98354.1 - 0.00021 21.8 0.0 0.00035 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON98354.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Vps53_N PF04100.7 EON98355.1 - 2.1e-101 339.4 0.7 4.1e-101 338.5 0.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EON98355.1 - 1.3e-05 24.2 4.4 2.5e-05 23.3 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EON98355.1 - 0.00026 20.8 0.1 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.6 EON98355.1 - 0.0013 17.4 0.6 0.0024 16.6 0.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Zw10 PF06248.8 EON98355.1 - 0.027 12.6 6.9 0.0099 14.0 1.4 2.4 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 Sec15 PF04091.7 EON98355.1 - 0.043 13.1 0.0 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF3510 PF12022.3 EON98355.1 - 0.044 13.8 0.5 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Thg1C PF14413.1 EON98356.1 - 1e-26 93.0 0.7 1.2e-26 92.7 0.5 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Pilus_PilP PF11356.3 EON98356.1 - 0.043 14.0 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Type IV pilus biogenesis Sucrose_synth PF00862.14 EON98356.1 - 0.056 11.4 0.0 0.066 11.1 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase DUF3578 PF12102.3 EON98356.1 - 0.12 12.0 0.9 0.14 11.7 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3578) DUF2229 PF09989.4 EON98356.1 - 0.19 11.1 0.8 0.23 10.8 0.6 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Nsp1 PF11501.3 EON98357.1 - 0.096 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Non structural protein Nsp1 Glyco_hydro_47 PF01532.15 EON98358.1 - 1.3e-173 577.8 0.1 1.5e-173 577.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Amidase PF01425.16 EON98359.1 - 1.8e-91 307.2 0.0 2.4e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy PF03171.15 EON98360.1 - 1.2e-13 51.1 0.1 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EON98361.1 - 0.019 15.4 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EON98362.1 - 5e-29 101.1 28.6 5e-29 101.1 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98362.1 - 3.4e-09 35.8 13.7 3.4e-09 35.8 9.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OPT PF03169.10 EON98363.1 - 3e-124 415.7 38.5 3.5e-124 415.5 26.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPT PF03151.11 EON98364.1 - 8.5e-27 93.6 11.3 8.5e-27 93.6 7.8 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EON98364.1 - 1e-07 31.2 19.3 2.6e-06 26.5 13.4 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EON98364.1 - 0.019 14.9 29.7 0.079 13.0 6.0 2.6 2 0 0 2 2 2 0 EamA-like transporter family Acyl-CoA_dh_1 PF00441.19 EON98365.1 - 1.2e-29 103.4 2.5 1.7e-29 102.8 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON98365.1 - 3.1e-19 68.2 0.6 5.4e-19 67.4 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EON98365.1 - 2e-08 34.7 0.9 4.9e-07 30.3 0.0 2.9 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EON98365.1 - 1.5e-06 28.4 0.3 2.3e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LamB_YcsF PF03746.11 EON98366.1 - 4.4e-48 163.4 0.0 5.2e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF2274 PF10038.4 EON98368.1 - 0.06 13.4 0.4 0.87 9.7 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2274) DUF3261 PF11659.3 EON98368.1 - 0.069 12.7 0.5 0.098 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) DUF417 PF04224.7 EON98368.1 - 1.9 7.8 5.7 0.6 9.4 1.2 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF417 EthD PF07110.6 EON98369.1 - 1.8e-23 83.2 1.5 2.2e-23 82.9 1.1 1.1 1 0 0 1 1 1 1 EthD domain AMP-binding PF00501.23 EON98370.1 - 2.2e-27 95.4 0.1 2.7e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON98370.1 - 1.4e-13 51.5 0.0 2.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 EON98371.1 - 5e-14 52.3 0.0 8.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98371.1 - 1.5e-07 31.1 0.0 5.2e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98371.1 - 9.5e-06 26.0 0.0 5.9e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98371.1 - 0.0001 22.7 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98371.1 - 0.00021 21.8 0.0 0.0011 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EON98371.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Acetyltransf_1 PF00583.19 EON98372.1 - 4.1e-06 26.7 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EON98372.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AHS1 PF02682.11 EON98374.1 - 4e-25 88.4 0.0 7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_lipoyl PF00364.17 EON98374.1 - 7.6e-11 41.5 4.3 8e-11 41.4 0.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EON98374.1 - 2.9e-05 23.6 1.0 0.019 14.6 0.1 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like AHS2 PF02626.10 EON98374.1 - 0.0014 17.9 0.0 0.0064 15.8 0.0 2.0 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 HlyD_3 PF13437.1 EON98374.1 - 0.057 13.7 0.3 0.19 12.0 0.1 1.9 1 1 1 2 2 2 0 HlyD family secretion protein EMP24_GP25L PF01105.19 EON98374.1 - 0.092 12.4 0.4 1.4 8.6 0.3 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD adh_short PF00106.20 EON98375.1 - 4.5e-56 189.3 11.1 1.2e-28 100.1 1.5 2.7 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EON98375.1 - 6.2e-26 90.1 0.0 1.8e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EON98375.1 - 1.8e-25 89.6 5.3 1.1e-13 51.3 1.3 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EON98375.1 - 5.8e-14 52.4 2.4 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 EON98375.1 - 9.5e-11 41.6 0.0 4e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MFS_1 PF07690.11 EON98376.1 - 1.4e-21 76.5 4.7 1.4e-21 76.5 3.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Voltage_CLC PF00654.15 EON98376.1 - 0.013 14.5 17.8 0.031 13.2 8.7 2.1 2 0 0 2 2 2 0 Voltage gated chloride channel Glyco_hydro_cc PF11790.3 EON98377.1 - 2.5e-61 207.1 0.7 2.9e-61 206.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CorA PF01544.13 EON98379.1 - 2.8e-05 23.3 5.1 8e-05 21.8 3.5 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_44 PF12891.2 EON98379.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 7TM_GPCR_Srw PF10324.4 EON98379.1 - 0.092 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ELYS PF13934.1 EON98380.1 - 2.6e-65 220.3 0.0 3.1e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly NmrA PF05368.8 EON98381.1 - 7.1e-17 61.4 0.3 9.3e-17 61.0 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98381.1 - 6.1e-14 52.4 0.9 6.1e-14 52.4 0.6 1.6 1 1 1 2 2 2 1 NADH(P)-binding DFP PF04127.10 EON98381.1 - 9.5e-05 22.0 1.3 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.19 EON98381.1 - 0.00018 21.7 2.0 0.0022 18.3 0.7 2.5 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EON98381.1 - 0.0024 17.3 0.2 0.0051 16.2 0.2 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EON98381.1 - 0.0058 16.5 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EON98381.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EON98381.1 - 0.024 13.5 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 EON98381.1 - 0.092 12.3 0.4 0.18 11.4 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 EON98382.1 - 5.7e-37 127.1 0.0 7.3e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 EON98382.1 - 1.2e-20 74.1 0.0 1.8e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 HMGL-like FlbD PF06289.6 EON98382.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) Pyr_redox_3 PF13738.1 EON98383.1 - 1.3e-22 80.8 0.0 2.9e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON98383.1 - 4.2e-07 28.5 0.0 8.2e-05 20.9 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EON98383.1 - 5.1e-07 28.9 0.0 0.00027 19.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EON98383.1 - 0.00011 22.1 0.1 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON98383.1 - 0.00029 20.7 0.1 0.1 12.4 0.0 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EON98383.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EON98383.1 - 0.037 14.1 0.0 0.16 12.0 0.0 2.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SprB PF13573.1 EON98383.1 - 0.94 9.1 6.3 0.19 11.3 0.7 2.2 2 0 0 2 2 2 0 SprB repeat adh_short PF00106.20 EON98384.1 - 2.6e-21 76.2 0.0 3.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98384.1 - 9.1e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EON98384.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EON98384.1 - 0.042 14.2 0.1 0.081 13.3 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4185 PF13810.1 EON98385.1 - 0.0069 15.3 0.1 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) DUF4064 PF13273.1 EON98385.1 - 0.86 9.7 13.3 0.042 13.9 1.9 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) FMO-like PF00743.14 EON98386.1 - 1.7e-16 59.5 0.0 4e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EON98386.1 - 2.4e-16 60.4 0.0 1.6e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON98386.1 - 2.5e-09 36.5 0.2 5.4e-07 28.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EON98386.1 - 2.5e-08 34.0 0.0 6.9e-07 29.3 0.0 3.2 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON98386.1 - 7.1e-06 26.3 1.3 0.13 12.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON98386.1 - 8.5e-06 25.0 0.3 0.0043 16.1 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON98386.1 - 0.00014 20.9 0.0 0.1 11.5 0.0 3.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EON98386.1 - 0.0002 20.3 0.2 3.6 6.3 0.0 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EON98386.1 - 0.00023 21.1 0.2 0.0047 16.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EON98386.1 - 0.00071 19.6 0.0 0.11 12.6 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EON98386.1 - 0.001 18.2 0.0 0.14 11.3 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EON98386.1 - 0.0036 16.9 0.4 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EON98386.1 - 0.0077 15.3 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EON98386.1 - 0.018 14.5 0.5 0.4 10.0 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EON98386.1 - 0.021 15.0 0.3 0.46 10.7 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EON98386.1 - 0.094 11.7 0.2 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_9 PF13454.1 EON98386.1 - 0.73 9.5 2.5 21 4.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thiolase_C PF02803.13 EON98387.1 - 1.2e-10 40.8 0.4 3e-09 36.3 0.0 2.3 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EON98387.1 - 1.4e-06 27.8 0.0 1.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EON98387.1 - 4.1e-05 23.1 0.1 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EON98387.1 - 0.00092 18.2 0.4 0.011 14.7 0.0 2.5 2 1 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 EON98387.1 - 0.049 13.4 0.1 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.3 EON98387.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SnoaL_2 PF12680.2 EON98388.1 - 0.00014 22.1 0.0 0.00018 21.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EON98388.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Glyco_hydro_42 PF02449.10 EON98389.1 - 3.3e-12 46.2 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EON98389.1 - 1.7e-07 30.9 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EON98389.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 adh_short PF00106.20 EON98390.1 - 2.8e-31 108.6 0.2 3.3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98390.1 - 2.9e-21 76.3 0.0 1.2e-20 74.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON98390.1 - 9.1e-15 54.7 0.1 1.2e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON98390.1 - 0.0054 16.7 0.2 0.008 16.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EON98390.1 - 0.052 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EON98390.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EON98390.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_transf_3 PF02515.12 EON98391.1 - 5e-61 205.2 0.0 7e-61 204.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_M19 PF01244.16 EON98392.1 - 3e-46 157.8 0.1 3.4e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) COesterase PF00135.23 EON98393.1 - 3.6e-20 72.1 0.0 4.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family CN_hydrolase PF00795.17 EON98394.1 - 5e-20 71.6 0.0 1.5e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase AMP-binding PF00501.23 EON98395.1 - 2.1e-21 75.8 0.5 3.4e-16 58.6 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EON98395.1 - 6.6e-07 30.1 0.1 1.3e-06 29.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 EON98396.1 - 1e-63 215.5 21.4 1.3e-63 215.1 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98396.1 - 2.3e-09 36.4 43.9 1.2e-08 34.0 6.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EON98397.1 - 2.5e-65 218.9 0.0 3.1e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EON98397.1 - 1e-33 116.9 17.1 1.4e-33 116.4 11.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EON98397.1 - 2.7e-16 59.4 1.5 0.00011 21.5 0.0 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EON98397.1 - 6.2e-12 46.0 0.0 0.1 12.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EON98397.1 - 3.1e-10 39.4 0.3 0.00035 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EON98397.1 - 5e-07 30.5 0.3 0.02 15.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EON98397.1 - 4.5e-06 26.8 0.2 0.49 10.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EON98397.1 - 5.7e-06 26.7 1.0 0.011 16.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC_ATPase PF09818.4 EON98397.1 - 1.2e-05 24.1 1.5 0.005 15.4 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EON98397.1 - 1.4e-05 24.3 0.0 0.15 11.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EON98397.1 - 1.5e-05 24.9 2.1 0.0061 16.3 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EON98397.1 - 2.3e-05 23.9 1.2 0.19 11.1 0.0 3.6 3 0 0 3 3 3 2 AAA-like domain AAA_30 PF13604.1 EON98397.1 - 4.2e-05 23.2 5.7 0.061 12.9 0.1 4.4 3 2 1 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EON98397.1 - 4.9e-05 22.5 0.0 0.1 11.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EON98397.1 - 5.7e-05 22.5 1.1 0.45 9.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EON98397.1 - 0.00011 22.3 0.3 5.7 7.1 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EON98397.1 - 0.00021 20.9 0.1 0.063 12.9 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.1 EON98397.1 - 0.00025 20.9 3.4 0.33 10.8 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EON98397.1 - 0.00033 20.5 0.0 0.84 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EON98397.1 - 0.00078 19.7 0.1 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EON98397.1 - 0.0011 18.7 0.1 2.9 7.6 0.0 3.4 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EON98397.1 - 0.0012 18.3 0.1 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EON98397.1 - 0.0014 18.1 0.1 0.14 11.6 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.1 EON98397.1 - 0.003 16.1 0.1 2.6 6.4 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3987) AAA_16 PF13191.1 EON98397.1 - 0.0064 16.4 15.0 0.15 11.9 2.1 3.8 2 2 2 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 EON98397.1 - 0.0094 15.8 0.0 1.6 8.6 0.0 3.1 4 0 0 4 4 2 1 AAA domain MobB PF03205.9 EON98397.1 - 0.018 14.7 1.5 1.5 8.5 0.0 3.2 3 1 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EON98397.1 - 0.033 13.3 0.1 0.85 8.7 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EON98397.1 - 0.049 13.5 0.6 16 5.4 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EON98397.1 - 0.054 12.6 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EON98397.1 - 0.064 13.4 0.1 19 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EON98397.1 - 0.096 11.5 0.1 11 4.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 EON98397.1 - 0.12 11.9 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EON98397.1 - 0.18 11.2 0.5 17 4.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Tannase PF07519.6 EON98398.1 - 3.5e-99 332.6 0.4 5.8e-99 331.9 0.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EON98398.1 - 0.004 16.9 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Inhibitor_I9 PF05922.11 EON98399.1 - 2.9e-18 66.2 0.0 5.6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 EON98399.1 - 2.6e-14 53.0 0.2 4e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_17 PF00332.13 EON98400.1 - 7.3e-05 21.9 0.4 0.00011 21.3 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 ADH_zinc_N PF00107.21 EON98401.1 - 3.7e-11 42.6 0.0 6.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98401.1 - 1.1e-07 31.5 0.0 3.8e-07 29.8 0.1 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AA_permease PF00324.16 EON98403.1 - 5.9e-99 331.5 28.6 7.1e-99 331.3 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON98403.1 - 1.5e-32 112.7 30.1 1.8e-32 112.4 20.9 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EON98404.1 - 0.23 10.1 10.3 0.073 11.7 4.7 1.7 2 0 0 2 2 2 0 Major Facilitator Superfamily Amidohydro_4 PF13147.1 EON98405.1 - 4.8e-29 102.2 0.1 3.8e-28 99.2 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EON98405.1 - 2e-14 53.1 4.2 2.5e-14 52.8 0.3 2.9 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 EON98405.1 - 2.3e-14 53.7 0.1 6.6e-08 32.5 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EON98405.1 - 1.3e-12 47.6 0.1 3.1e-08 33.2 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EON98405.1 - 0.022 14.8 2.5 0.087 12.9 0.5 2.6 2 1 1 3 3 3 0 Urease alpha-subunit, N-terminal domain Methyltransf_23 PF13489.1 EON98406.1 - 1.6e-15 57.1 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON98406.1 - 1.1e-13 51.4 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98406.1 - 6.6e-12 45.7 0.0 9.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98406.1 - 4.3e-11 43.3 0.0 6.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98406.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98406.1 - 6.4e-08 32.3 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EON98406.1 - 3.8e-07 29.4 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EON98406.1 - 1.5e-06 28.2 0.1 4.6e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON98406.1 - 1.6e-05 24.3 0.0 3.5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EON98406.1 - 2.9e-05 23.1 0.0 3.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EON98406.1 - 5.4e-05 22.4 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 EON98406.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_19 PF04672.7 EON98406.1 - 0.00018 20.8 0.0 0.16 11.2 0.0 2.1 1 1 1 2 2 2 2 S-adenosyl methyltransferase PCMT PF01135.14 EON98406.1 - 0.00058 19.4 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.7 EON98406.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase UDPG_MGDP_dh_N PF03721.9 EON98406.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MetW PF07021.7 EON98406.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Peripla_BP_4 PF13407.1 EON98406.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain N2227 PF07942.7 EON98406.1 - 0.03 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein Ubie_methyltran PF01209.13 EON98406.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.13 EON98406.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_9 PF08003.6 EON98406.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Peptidase_A4 PF01828.12 EON98407.1 - 3.6e-86 287.5 11.1 4.3e-86 287.2 7.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family EcKinase PF02958.15 EON98408.1 - 6.6e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EON98408.1 - 1.2e-10 41.5 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EON98408.1 - 0.0049 15.5 0.0 0.007 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Acyl-CoA_dh_1 PF00441.19 EON98409.1 - 3.9e-37 127.6 2.8 5.7e-37 127.1 1.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EON98409.1 - 2.2e-14 53.8 0.7 3.8e-14 53.0 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON98409.1 - 7.6e-12 44.5 0.1 1.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EON98409.1 - 5.5e-10 39.8 0.0 3.8e-09 37.1 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EON98409.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.18 EON98410.1 - 1.8e-25 90.0 0.0 2.3e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EON98410.1 - 0.0062 15.9 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Acyl-CoA_dh_1 PF00441.19 EON98411.1 - 1.6e-34 119.1 2.5 2.7e-34 118.4 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EON98411.1 - 1.1e-24 87.2 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EON98411.1 - 2e-14 53.9 0.3 7.9e-14 52.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON98411.1 - 1.9e-13 49.6 0.0 4.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glucosaminidase PF01832.15 EON98411.1 - 0.0039 17.3 0.6 0.016 15.3 0.1 2.0 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase ANAPC15 PF15243.1 EON98412.1 - 0.086 12.9 4.1 0.17 11.9 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RE_TdeIII PF09520.5 EON98412.1 - 0.096 11.9 0.3 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 Type II restriction endonuclease, TdeIII CENP-B_dimeris PF09026.5 EON98412.1 - 9.6 6.5 13.4 22 5.3 8.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Fungal_trans PF04082.13 EON98413.1 - 1.1e-28 99.8 0.4 1.6e-28 99.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_C PF02752.17 EON98414.1 - 0.0019 18.3 0.0 2.6 8.1 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DUF1542 PF07564.6 EON98414.1 - 0.032 14.2 0.3 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) SnoaL_4 PF13577.1 EON98415.1 - 1.7e-23 82.9 1.7 2e-23 82.6 1.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EON98415.1 - 0.00026 21.3 1.7 0.00041 20.7 1.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EON98415.1 - 0.0034 17.5 1.0 0.0046 17.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EON98415.1 - 0.008 16.2 1.0 0.015 15.3 0.7 1.4 1 1 0 1 1 1 1 SnoaL-like domain CFIA_Pcf11 PF11526.3 EON98415.1 - 0.13 12.3 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Binary_toxB PF03495.9 EON98416.1 - 0.069 11.7 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA TSP_3 PF02412.13 EON98416.1 - 0.11 12.0 1.1 2.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Thrombospondin type 3 repeat MFS_1 PF07690.11 EON98417.1 - 5.7e-32 110.8 30.1 5.7e-32 110.8 20.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 EON98418.1 - 2.8e-41 141.0 21.4 3.8e-41 140.5 14.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EON98418.1 - 2.8e-16 60.0 0.3 4.7e-16 59.3 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EON98418.1 - 4.3e-06 26.9 1.5 0.024 14.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 EON98418.1 - 3.7e-05 23.6 0.0 7.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EON98418.1 - 8.7e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EON98418.1 - 9.7e-05 21.8 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EON98418.1 - 0.00017 22.4 0.0 0.0004 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON98418.1 - 0.00022 21.5 0.1 0.00055 20.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EON98418.1 - 0.0003 20.8 0.3 0.0014 18.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EON98418.1 - 0.00039 19.7 0.1 0.031 13.5 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EON98418.1 - 0.00042 19.7 0.0 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EON98418.1 - 0.00053 20.1 0.1 0.036 14.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain T2SE PF00437.15 EON98418.1 - 0.0033 16.3 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EON98418.1 - 0.0055 16.2 0.1 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EON98418.1 - 0.0074 15.7 0.2 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EON98418.1 - 0.011 15.7 0.9 0.011 15.7 0.7 2.0 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EON98418.1 - 0.014 14.1 0.0 0.079 11.6 0.0 1.9 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EON98418.1 - 0.02 14.8 0.2 0.041 13.8 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 EON98418.1 - 0.029 14.0 0.2 0.068 12.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EON98418.1 - 0.043 13.3 0.1 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EON98418.1 - 0.044 13.4 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EON98418.1 - 0.044 13.2 0.3 0.094 12.2 0.2 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EON98418.1 - 0.046 12.7 0.0 5.1 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EON98418.1 - 0.049 13.4 0.1 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 EON98418.1 - 0.049 12.6 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin APS_kinase PF01583.15 EON98418.1 - 0.098 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase FeoB_N PF02421.13 EON98418.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.1 EON98418.1 - 5.8 6.4 5.3 1.8 8.0 0.2 2.4 3 0 0 3 3 3 0 AAA domain GMC_oxred_N PF00732.14 EON98419.1 - 1.2e-77 261.0 0.0 1.8e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON98419.1 - 1.6e-35 122.5 0.1 3.5e-35 121.4 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EON98419.1 - 7.2e-06 25.1 0.0 0.0071 15.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON98419.1 - 0.0013 17.7 0.1 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EON98419.1 - 0.0013 17.6 0.0 0.81 8.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EON98419.1 - 0.015 14.4 0.0 0.043 12.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EON98419.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MARVEL PF01284.18 EON98420.1 - 1.3e-05 25.0 12.4 1.7e-05 24.6 8.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EON98420.1 - 1.6 7.9 10.5 2.6 7.2 7.3 1.3 1 1 0 1 1 1 0 Tetraspanin family Pyr_redox_3 PF13738.1 EON98421.1 - 9.3e-29 100.9 0.0 1.6e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON98421.1 - 1.4e-19 69.6 0.7 1.2e-18 66.6 0.2 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EON98421.1 - 5.1e-12 45.6 0.0 2.7e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EON98421.1 - 5.8e-11 41.8 1.1 1.8e-09 36.9 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EON98421.1 - 3.4e-09 36.0 0.3 7.7e-07 28.3 0.2 2.7 1 1 2 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON98421.1 - 2.3e-08 34.1 0.0 0.00013 21.8 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EON98421.1 - 1.3e-06 27.6 0.2 0.0015 17.6 0.0 2.5 3 0 0 3 3 3 2 Thi4 family FAD_oxidored PF12831.2 EON98421.1 - 2.5e-06 26.8 0.1 5.1e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON98421.1 - 5.7e-06 26.6 0.3 0.0064 16.8 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON98421.1 - 2.1e-05 23.5 0.4 0.00069 18.5 0.2 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EON98421.1 - 2.5e-05 23.5 0.1 0.0033 16.5 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EON98421.1 - 3.9e-05 22.8 0.0 0.00037 19.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EON98421.1 - 5.3e-05 22.2 0.0 0.0014 17.6 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EON98421.1 - 0.00025 20.0 0.1 0.00082 18.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EON98421.1 - 0.00048 19.9 0.2 0.01 15.5 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EON98421.1 - 0.0011 17.4 0.1 0.0058 15.1 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EON98421.1 - 0.0014 18.2 0.5 0.004 16.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EON98421.1 - 0.01 15.0 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EON98421.1 - 0.011 15.7 0.0 11 6.1 0.0 3.3 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EON98421.1 - 0.025 14.4 0.0 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EON98421.1 - 0.099 12.2 0.3 7.9 6.0 0.0 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EON98421.1 - 0.94 9.2 3.4 6.2 6.5 0.7 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding SMC_N PF02463.14 EON98422.1 - 1.2e-68 230.6 37.9 1.4e-67 227.1 26.3 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EON98422.1 - 5.1e-27 94.2 0.0 2.8e-26 91.8 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EON98422.1 - 2.9e-11 43.8 10.0 1.9e-05 24.7 0.0 3.9 3 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EON98422.1 - 2.2e-09 37.9 8.8 2.2e-09 37.9 6.1 6.6 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 EON98422.1 - 0.00022 20.7 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EON98422.1 - 0.0053 16.3 11.3 0.0053 16.3 7.8 8.4 4 2 5 9 9 9 3 IncA protein Laminin_II PF06009.7 EON98422.1 - 0.0077 15.9 3.9 0.0077 15.9 2.7 8.8 3 2 5 8 8 8 2 Laminin Domain II Reo_sigmaC PF04582.7 EON98422.1 - 0.87 8.7 39.8 0.091 11.9 1.8 6.0 3 2 3 6 6 6 0 Reovirus sigma C capsid protein ADH_N PF08240.7 EON98423.1 - 1.2e-28 99.0 0.4 3.4e-28 97.5 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON98423.1 - 1.1e-22 80.0 0.1 1.8e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON98423.1 - 9.9e-06 26.4 0.0 2.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EON98423.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EON98423.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EON98423.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EON98424.1 - 1.5e-17 64.0 0.4 3.6e-17 62.7 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98424.1 - 4.9e-11 42.6 0.0 7.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON98424.1 - 2.1e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON98424.1 - 9.7e-07 28.4 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON98424.1 - 0.057 13.4 1.0 0.14 12.1 0.7 1.7 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 EON98425.1 - 3.3e-89 299.5 18.4 3.8e-89 299.3 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98425.1 - 1.1e-16 60.5 28.4 1.1e-16 60.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EON98425.1 - 0.013 15.4 6.8 0.98 9.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) ADH_N PF08240.7 EON98426.1 - 1.4e-27 95.6 0.6 1.4e-27 95.6 0.4 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON98426.1 - 1.5e-14 53.6 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EON98426.1 - 0.04 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Amidohydro_1 PF01979.15 EON98427.1 - 3.3e-14 53.2 0.7 1.1e-13 51.5 0.5 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EON98427.1 - 2.9e-13 49.4 0.1 1e-12 47.6 0.1 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EON98427.1 - 3.8e-07 30.4 4.4 1.4e-06 28.5 1.9 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EON98427.1 - 5e-05 22.6 2.0 0.018 14.2 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family adh_short PF00106.20 EON98428.1 - 5.1e-30 104.5 5.1 5.9e-30 104.3 3.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98428.1 - 5.7e-17 62.2 1.6 7.1e-17 61.9 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON98428.1 - 2.3e-14 53.4 2.5 3.1e-14 53.0 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON98428.1 - 0.00039 19.9 1.5 0.0011 18.4 1.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EON98428.1 - 0.0097 15.9 4.2 0.053 13.5 2.9 2.0 1 1 0 1 1 1 1 NADH(P)-binding AIRC PF00731.15 EON98428.1 - 0.024 13.9 1.5 0.039 13.2 0.1 1.9 2 0 0 2 2 2 0 AIR carboxylase Glyco_trans_4_4 PF13579.1 EON98428.1 - 0.025 14.7 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF1088 PF06469.6 EON98429.1 - 0.085 12.2 0.2 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) TilS PF09179.6 EON98429.1 - 0.14 12.2 0.2 4.1 7.5 0.0 2.8 3 0 0 3 3 3 0 TilS substrate binding domain LTXXQ PF07813.7 EON98430.1 - 1.9 8.9 4.6 9.6 6.7 0.2 2.6 2 1 0 2 2 2 0 LTXXQ motif family protein adh_short PF00106.20 EON98431.1 - 9.1e-30 103.7 0.1 1.1e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98431.1 - 1.8e-28 99.9 0.0 2.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON98431.1 - 1.4e-14 54.1 0.1 1.8e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Thg1 PF04446.7 EON98432.1 - 0.12 11.9 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 tRNAHis guanylyltransferase Img2 PF05046.9 EON98433.1 - 8.1e-22 77.2 0.0 1e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Pheromone PF08015.6 EON98433.1 - 6.4 7.6 6.8 11 6.9 4.7 1.4 1 0 0 1 1 1 0 Fungal mating-type pheromone Aldo_ket_red PF00248.16 EON98434.1 - 6.4e-25 87.5 0.0 1.4e-24 86.4 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.1 EON98435.1 - 2e-61 207.8 23.5 2.7e-61 207.4 16.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON98435.1 - 5.5e-15 54.6 21.5 8.4e-15 54.0 14.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EON98435.1 - 0.95 9.4 4.0 2.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) DUF1469 PF07332.6 EON98435.1 - 8.3 6.1 8.8 0.69 9.6 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) ARID PF01388.16 EON98436.1 - 6.6e-17 61.1 0.0 3.5e-16 58.8 0.0 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 EON98436.1 - 0.029 13.1 0.5 0.25 10.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3518) His_Phos_2 PF00328.17 EON98437.1 - 4.2e-26 92.0 0.0 5.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EON98437.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Peptidase_S8 PF00082.17 EON98438.1 - 4.8e-09 35.7 0.2 6.8e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EON98438.1 - 0.016 15.7 0.1 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 FTR PF01913.13 EON98438.1 - 0.066 12.9 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase DUF239 PF03080.10 EON98440.1 - 2.7e-35 121.5 11.2 3.9e-35 121.0 7.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF239) HRXXH PF13933.1 EON98441.1 - 6.5e-70 235.3 0.1 7.6e-70 235.1 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family Cellulase PF00150.13 EON98442.1 - 1.9e-20 73.2 3.1 3.6e-20 72.3 2.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_101 PF12905.2 EON98442.1 - 0.011 14.4 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Mpv17_PMP22 PF04117.7 EON98442.1 - 0.069 12.7 1.5 0.48 10.0 0.1 2.8 2 0 0 2 2 2 0 Mpv17 / PMP22 family E1-E2_ATPase PF00122.15 EON98444.1 - 2.6e-50 170.5 8.3 6.1e-50 169.4 5.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EON98444.1 - 4.4e-26 92.6 0.1 7.4e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EON98444.1 - 5e-15 56.1 0.0 1e-14 55.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON98444.1 - 4.4e-05 23.1 0.1 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EON98444.1 - 0.026 14.6 1.6 0.053 13.6 0.1 2.3 2 0 0 2 2 2 0 Heavy-metal-associated domain EutQ PF06249.7 EON98446.1 - 1.5e-12 47.3 0.0 1.8e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EON98446.1 - 1.5e-09 37.0 0.1 3.5e-09 35.9 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EON98446.1 - 2.7e-05 23.5 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EON98446.1 - 0.0011 18.6 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EON98446.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Methyltransf_23 PF13489.1 EON98447.1 - 1e-08 35.0 0.0 2e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98447.1 - 1.1e-06 29.2 0.1 2.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98447.1 - 2.9e-06 26.9 0.0 5.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON98447.1 - 0.0002 20.4 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EON98447.1 - 0.00057 20.3 0.0 0.0015 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98447.1 - 0.0017 18.8 0.1 0.0039 17.6 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EON98447.1 - 0.0019 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EON98447.1 - 0.0035 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EON98447.1 - 0.0051 16.8 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EON98447.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EON98447.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EON98447.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EON98447.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Amidase PF01425.16 EON98448.1 - 8.7e-13 47.9 0.0 1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Aldedh PF00171.17 EON98449.1 - 1.3e-120 402.9 0.0 1.5e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EON98449.1 - 0.00037 19.3 0.0 0.00092 18.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) BRCA-2_OB3 PF09104.5 EON98449.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 zf-C2H2_4 PF13894.1 EON98450.1 - 0.8 10.1 8.6 0.17 12.3 1.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EON98450.1 - 4.1 7.9 6.9 13 6.3 1.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type p450 PF00067.17 EON98451.1 - 1.6e-59 201.6 0.0 2e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1989 PF09347.5 EON98452.1 - 2.2e-51 173.5 0.0 4.1e-51 172.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 EON98452.1 - 1.9e-18 66.2 0.0 3.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EON98452.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 EON98452.1 - 0.068 11.2 0.0 0.1 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) MFS_1 PF07690.11 EON98453.1 - 2.1e-37 128.6 26.1 2.1e-37 128.6 18.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98453.1 - 2.7e-11 42.7 29.8 3.2e-10 39.1 20.2 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter DEAD PF00270.24 EON98454.1 - 3e-42 143.9 0.0 4.2e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON98454.1 - 1.2e-23 82.7 0.1 2.2e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON98454.1 - 0.018 14.8 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NAD_binding_4 PF07993.7 EON98455.1 - 3.7e-32 111.2 0.0 5.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EON98455.1 - 1.9e-19 69.3 0.0 3.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EON98455.1 - 2.8e-13 49.8 0.0 6.2e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EON98455.1 - 1.1e-07 31.9 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EON98455.1 - 6e-05 23.0 0.0 0.00031 20.7 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EON98455.1 - 0.0023 16.8 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EON98455.1 - 0.0082 15.8 0.0 0.08 12.6 0.0 2.7 2 1 0 2 2 2 1 KR domain Peptidase_M20 PF01546.23 EON98456.1 - 4.7e-18 65.3 0.2 6.7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON98456.1 - 3.2e-05 23.6 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EON98456.1 - 0.00042 20.0 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Ribosomal_S10 PF00338.17 EON98457.1 - 2.2e-29 101.1 0.4 2.6e-29 100.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.4 EON98457.1 - 0.035 12.4 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF4469 PF14734.1 EON98457.1 - 0.083 12.7 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold SnoaL PF07366.7 EON98458.1 - 0.00047 19.7 0.0 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EON98458.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain AAA_13 PF13166.1 EON98459.1 - 9.5e-06 24.3 23.2 3.8e-05 22.3 0.1 3.2 2 1 1 3 3 3 1 AAA domain IncA PF04156.9 EON98459.1 - 0.00016 21.3 31.4 0.052 13.1 8.0 4.5 3 1 2 5 5 5 4 IncA protein Reo_sigmaC PF04582.7 EON98459.1 - 0.0022 17.2 24.7 0.0035 16.5 2.0 4.9 3 2 3 6 6 6 2 Reovirus sigma C capsid protein ADIP PF11559.3 EON98459.1 - 0.0028 17.5 42.9 0.0036 17.2 0.2 5.5 3 2 2 5 5 5 2 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 EON98459.1 - 0.014 14.8 31.1 0.026 13.9 1.0 5.2 3 2 3 6 6 6 0 Phage minor structural protein GP20 V-SNARE PF05008.10 EON98459.1 - 0.031 14.4 0.7 0.031 14.4 0.5 5.0 4 1 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus HR1 PF02185.11 EON98459.1 - 0.044 13.5 24.8 0.22 11.3 0.8 5.6 4 1 0 4 4 4 0 Hr1 repeat IFT46_B_C PF12317.3 EON98459.1 - 0.18 11.1 3.2 1.2 8.4 0.1 2.8 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal CD52 PF15116.1 EON98459.1 - 0.18 11.6 0.7 0.49 10.2 0.5 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen ERM PF00769.14 EON98459.1 - 0.21 11.0 39.8 1 8.8 0.3 4.3 3 1 1 4 4 4 0 Ezrin/radixin/moesin family ATG16 PF08614.6 EON98459.1 - 0.26 11.0 46.3 0.12 12.1 0.4 6.0 3 3 2 5 5 5 0 Autophagy protein 16 (ATG16) Syntaxin PF00804.20 EON98459.1 - 0.29 11.3 27.0 0.39 10.9 2.9 5.4 3 2 1 4 4 4 0 Syntaxin Atg14 PF10186.4 EON98459.1 - 0.41 9.5 34.6 0.55 9.1 0.9 3.8 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Nsp1_C PF05064.8 EON98459.1 - 0.52 9.9 17.2 0.014 15.0 2.8 4.1 4 1 0 4 4 4 0 Nsp1-like C-terminal region TMF_DNA_bd PF12329.3 EON98459.1 - 0.84 9.4 38.6 0.21 11.3 0.6 5.8 5 1 0 5 5 5 0 TATA element modulatory factor 1 DNA binding zf-ZPR1 PF03367.8 EON98459.1 - 1.7 7.7 6.1 0.3 10.2 0.2 2.8 3 1 0 3 3 3 0 ZPR1 zinc-finger domain DUF489 PF04356.7 EON98459.1 - 1.9 8.0 9.2 3.2 7.2 1.0 3.6 2 2 0 3 3 3 0 Protein of unknown function (DUF489) DUF3573 PF12097.3 EON98459.1 - 2 6.9 6.9 3.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3573) Myosin_tail_1 PF01576.14 EON98459.1 - 3.9 5.0 43.0 1 7.0 2.6 4.8 3 1 0 4 4 4 0 Myosin tail SlyX PF04102.7 EON98459.1 - 3.9 7.9 29.2 4.6 7.6 2.2 6.4 5 1 1 6 6 6 0 SlyX V_ATPase_I PF01496.14 EON98459.1 - 5.3 4.7 17.0 0.66 7.7 3.9 3.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EON98459.1 - 7.1 5.1 35.5 0.28 9.7 3.3 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein DUF641 PF04859.7 EON98459.1 - 8 6.2 31.8 0.99 9.1 1.3 5.5 3 1 1 5 5 5 0 Plant protein of unknown function (DUF641) Iso_dh PF00180.15 EON98460.1 - 3.6e-104 348.4 0.0 4.6e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DIOX_N PF14226.1 EON98461.1 - 1.5e-16 60.9 0.1 1.8e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal U3_assoc_6 PF08640.6 EON98463.1 - 2.3e-25 88.1 0.3 1.7e-24 85.3 0.1 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EON98463.1 - 5.1e-05 23.5 1.5 0.0059 17.1 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EON98463.1 - 0.00018 20.4 0.0 0.0038 16.1 0.0 2.3 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Sigma70_ner PF04546.8 EON98463.1 - 0.017 14.7 1.3 0.017 14.7 0.9 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_11 PF13414.1 EON98463.1 - 0.043 13.4 0.1 0.26 10.9 0.1 2.4 2 0 0 2 2 2 0 TPR repeat PBP1_TM PF14812.1 EON98463.1 - 0.13 12.5 2.3 0.26 11.6 1.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ferritin_2 PF13668.1 EON98464.1 - 3.5e-44 150.0 3.4 5.2e-44 149.5 2.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.9 EON98464.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) NACHT PF05729.7 EON98465.1 - 3e-10 40.0 0.4 9.4e-09 35.1 0.1 3.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EON98465.1 - 3.9e-05 23.7 0.1 0.00042 20.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EON98465.1 - 0.00033 21.4 0.1 0.0038 18.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EON98465.1 - 0.00054 20.1 0.0 0.0045 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EON98465.1 - 0.00089 19.5 0.0 0.0027 17.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 EON98465.1 - 0.00099 19.2 0.1 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EON98465.1 - 0.0014 18.1 0.1 0.0057 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EON98465.1 - 0.0016 17.8 1.6 0.051 12.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EON98465.1 - 0.0056 16.5 1.6 0.011 15.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EON98465.1 - 0.0074 15.8 0.1 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EON98465.1 - 0.02 15.2 0.0 0.068 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EON98465.1 - 0.029 14.1 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EON98465.1 - 0.036 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.18 EON98465.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EON98465.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EON98465.1 - 0.056 13.6 0.3 0.47 10.6 0.0 2.8 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EON98465.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EON98465.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.4 2 1 1 3 3 2 0 AAA domain AAA_14 PF13173.1 EON98465.1 - 0.14 12.0 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EON98465.1 - 0.16 11.1 0.0 0.74 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ArgK PF03308.11 EON98465.1 - 0.25 10.0 1.0 0.38 9.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein dCMP_cyt_deam_1 PF00383.17 EON98466.1 - 1.1e-09 37.8 0.1 1.4e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Methyltransf_23 PF13489.1 EON98467.1 - 1.7e-10 40.8 0.0 1.1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98467.1 - 9.2e-07 29.2 0.0 9.4e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON98467.1 - 0.00019 20.6 0.0 0.0048 16.0 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EON98467.1 - 0.0019 18.6 0.0 0.008 16.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EON98467.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_31 PF13847.1 EON98467.1 - 0.034 13.7 0.0 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain PTSIIA_gutA PF03829.8 EON98467.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component FAD_binding_3 PF01494.14 EON98468.1 - 6.4e-11 41.8 4.6 1.1e-08 34.5 0.4 2.8 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 EON98468.1 - 0.0065 15.5 0.2 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EON98468.1 - 0.043 12.7 5.0 0.063 12.1 0.0 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON98468.1 - 0.32 9.8 5.3 1.2 7.9 0.0 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 EON98468.1 - 1.4 9.3 4.9 9.3 6.7 0.2 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON98469.1 - 6.6e-54 183.3 0.4 1.1e-51 175.9 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EON98469.1 - 1.9e-06 27.5 0.0 4.7e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EON98469.1 - 2.8e-06 26.6 0.1 4.2e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EON98469.1 - 3.5e-06 26.1 0.2 1.3e-05 24.3 0.1 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON98469.1 - 1.8e-05 24.7 0.2 0.00019 21.3 0.1 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON98469.1 - 1.9e-05 24.6 0.0 6.5e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EON98469.1 - 0.00036 20.8 0.0 0.0008 19.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON98469.1 - 0.0004 18.9 0.0 0.00067 18.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EON98469.1 - 0.0009 18.1 0.0 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EON98469.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EON98469.1 - 0.0099 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EON98469.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EON98469.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EON98469.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EON98469.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain eIF3_N PF09440.5 EON98471.1 - 1.9e-51 173.6 2.8 4.7e-51 172.4 2.0 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EON98471.1 - 3.7e-13 49.6 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain FAD_binding_3 PF01494.14 EON98472.1 - 1.6e-17 63.5 0.0 4.3e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON98472.1 - 7.2e-10 38.2 1.3 1.9e-05 23.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EON98472.1 - 2.6e-09 36.4 0.2 6.9e-09 35.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EON98472.1 - 9.8e-09 35.3 1.0 3.3e-08 33.6 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON98472.1 - 1.1e-08 33.9 0.1 1.4e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EON98472.1 - 2.2e-07 30.3 0.0 3.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON98472.1 - 3.2e-06 27.4 0.1 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON98472.1 - 8.7e-06 25.6 0.0 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EON98472.1 - 2.4e-05 23.3 0.0 4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EON98472.1 - 0.0001 21.1 0.1 0.24 9.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 EON98472.1 - 0.003 16.6 0.1 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EON98472.1 - 0.0041 17.1 0.2 0.014 15.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON98472.1 - 0.0066 15.4 0.1 0.021 13.7 0.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EON98472.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EON98472.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.17 EON98473.1 - 3.5e-120 401.4 3.8 7.2e-79 265.2 0.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 EON98473.1 - 0.00035 19.4 0.0 0.00053 18.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) CUE PF02845.11 EON98474.1 - 1.6e-10 40.2 0.1 2.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 CUE domain BTB PF00651.26 EON98475.1 - 5.3e-06 26.3 0.0 9.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FMN_dh PF01070.13 EON98476.1 - 4.6e-66 223.0 0.1 5.3e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EON98476.1 - 3.5e-06 26.1 1.8 5.4e-05 22.2 0.4 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EON98476.1 - 2.5e-05 23.3 0.1 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EON98476.1 - 0.00013 21.2 0.3 0.00026 20.2 0.2 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EON98476.1 - 0.016 14.4 0.1 0.039 13.2 0.1 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein Prothymosin PF03247.9 EON98476.1 - 0.032 14.3 3.8 0.05 13.7 2.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family ThiG PF05690.9 EON98476.1 - 0.046 12.8 0.1 0.3 10.1 0.1 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_18 PF00704.23 EON98477.1 - 3.9e-67 227.1 3.2 7.1e-67 226.2 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NmrA PF05368.8 EON98478.1 - 3.2e-17 62.5 0.0 3.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98478.1 - 6e-17 62.2 0.1 8.8e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON98478.1 - 0.00099 18.6 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EON98478.1 - 0.02 15.1 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EON98479.1 - 2.3e-27 95.6 35.9 4.5e-27 94.6 24.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EON98479.1 - 0.0013 18.7 1.1 0.0013 18.7 0.7 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) DUF4131 PF13567.1 EON98479.1 - 3.8 6.8 13.7 1.7 8.0 1.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3176 PF11374.3 EON98480.1 - 1.6e-29 102.0 1.3 1.6e-29 102.0 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3529 PF12046.3 EON98480.1 - 0.055 12.4 0.5 0.13 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) zf-CCCH PF00642.19 EON98481.1 - 0.13 11.9 3.6 0.064 12.9 0.7 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DnaJ PF00226.26 EON98482.1 - 1.1e-09 37.8 1.4 2.3e-09 36.8 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1471 PF07338.8 EON98482.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) MFS_1 PF07690.11 EON98483.1 - 8.7e-23 80.5 9.8 1.1e-22 80.2 6.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98483.1 - 1.2e-11 43.8 3.1 1.2e-11 43.8 2.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2207 PF09972.4 EON98483.1 - 0.015 13.9 0.8 0.077 11.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PTR2 PF00854.16 EON98483.1 - 0.041 12.6 6.9 0.47 9.1 0.6 2.3 2 0 0 2 2 2 0 POT family ATG22 PF11700.3 EON98483.1 - 0.1 11.0 12.8 0.012 14.1 4.9 1.9 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Frag1 PF10277.4 EON98484.1 - 4.6e-39 134.1 12.7 4.6e-39 134.1 8.8 3.0 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family adh_short PF00106.20 EON98485.1 - 2.9e-18 66.3 0.8 3.4e-18 66.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98485.1 - 8.9e-08 32.0 0.3 1.1e-07 31.7 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON98485.1 - 0.00072 19.3 0.1 0.00088 19.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EON98485.1 - 0.0048 16.5 0.5 0.0062 16.2 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EON98485.1 - 0.031 13.3 0.4 0.042 12.9 0.3 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EVE PF01878.13 EON98486.1 - 7.3e-50 168.7 0.7 8.6e-50 168.4 0.0 1.4 2 0 0 2 2 2 1 EVE domain DUF3292 PF11696.3 EON98486.1 - 0.018 12.9 3.3 0.022 12.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2486 PF10667.4 EON98486.1 - 1 9.8 12.7 1.7 9.1 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF2413 PF10310.4 EON98486.1 - 6.7 5.4 11.0 7.9 5.1 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Methyltransf_2 PF00891.13 EON98487.1 - 6.5e-16 58.2 0.0 1.2e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EON98487.1 - 0.00019 21.2 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Glyco_hydro_61 PF03443.9 EON98488.1 - 2.2e-50 171.5 0.5 3.5e-50 170.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 EON98488.1 - 2.4e-13 50.3 0.1 3.8e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98488.1 - 5.1e-08 32.7 0.1 9e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EON98488.1 - 0.0014 18.7 0.1 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EON98488.1 - 0.0035 17.7 0.2 0.0065 16.8 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Arg_repressor_C PF02863.13 EON98488.1 - 0.0056 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Eno-Rase_NADH_b PF12242.3 EON98488.1 - 0.019 14.7 0.9 0.051 13.3 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EON98488.1 - 0.022 13.6 0.2 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LsmAD PF06741.8 EON98488.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 LsmAD domain DUF2754 PF10953.3 EON98489.1 - 0.11 12.5 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Aldedh PF00171.17 EON98491.1 - 5.5e-86 288.7 0.1 6.9e-86 288.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 EON98491.1 - 0.13 11.8 0.4 1.1 8.9 0.1 2.3 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3328 PF11807.3 EON98492.1 - 3.2e-23 82.5 2.8 7.5e-23 81.3 1.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) RskA PF10099.4 EON98492.1 - 0.087 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CTNNBL PF08216.6 EON98493.1 - 1e-32 111.8 0.0 5.4e-32 109.5 0.0 2.3 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EON98493.1 - 0.00047 20.3 2.9 0.1 12.8 0.1 2.8 2 0 0 2 2 2 2 HEAT repeats Neurochondrin PF05536.6 EON98493.1 - 0.019 13.3 0.1 0.11 10.8 0.0 2.0 1 1 1 2 2 2 0 Neurochondrin DUF3361 PF11841.3 EON98493.1 - 0.024 14.3 0.5 0.2 11.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Orbi_NS3 PF01616.11 EON98493.1 - 0.078 11.9 0.8 8.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 IDO PF01231.13 EON98494.1 - 6.1e-108 360.9 0.0 7e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MFS_1 PF07690.11 EON98495.1 - 5.1e-26 91.2 59.5 9.5e-25 87.0 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FixP_N PF14715.1 EON98495.1 - 1.1 8.6 4.3 3 7.3 0.2 3.2 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Cu_amine_oxid PF01179.15 EON98496.1 - 1.4e-51 175.5 5.3 6.9e-39 133.7 0.1 3.1 1 1 2 3 3 3 3 Copper amine oxidase, enzyme domain STE2 PF02116.10 EON98497.1 - 6e-32 110.8 19.4 6.9e-32 110.6 13.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR RseC_MucC PF04246.7 EON98497.1 - 1.5 8.3 8.0 0.1 12.1 0.5 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC GTP_EFTU PF00009.22 EON98498.1 - 4.7e-47 159.8 0.0 7.3e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EON98498.1 - 3.1e-38 129.9 4.3 5.4e-38 129.2 3.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EON98498.1 - 6.6e-18 64.3 0.0 1.4e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EON98498.1 - 2.7e-06 27.3 0.2 7e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EON98498.1 - 5.8e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EON98498.1 - 0.00015 21.2 0.0 0.00042 19.7 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EON98498.1 - 0.0016 17.6 0.1 0.0075 15.4 0.0 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MFS_1 PF07690.11 EON98499.1 - 3.5e-07 29.2 16.4 3.5e-07 29.2 11.3 2.9 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EON98499.1 - 1.2e-05 23.7 15.0 1.5e-05 23.4 10.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_membrane PF00664.18 EON98500.1 - 2.1e-68 230.7 27.8 4.5e-38 131.2 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EON98500.1 - 2e-66 222.4 0.0 1.1e-31 110.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EON98500.1 - 6.5e-11 42.7 0.0 0.011 15.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EON98500.1 - 5.7e-10 38.7 1.4 0.0011 18.2 0.1 4.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EON98500.1 - 2.7e-09 36.4 0.1 0.0025 17.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EON98500.1 - 3.2e-09 37.6 0.0 0.00083 20.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EON98500.1 - 6.9e-08 32.6 3.1 0.0086 16.0 0.5 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EON98500.1 - 2.1e-06 27.9 0.1 0.23 11.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EON98500.1 - 2.6e-06 27.1 0.1 0.066 12.7 0.0 4.0 5 0 0 5 5 4 2 AAA domain AAA_23 PF13476.1 EON98500.1 - 9.2e-06 26.1 3.6 0.029 14.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EON98500.1 - 2.1e-05 23.7 0.0 0.036 13.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EON98500.1 - 2.8e-05 23.7 0.4 0.23 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 EON98500.1 - 5.8e-05 22.9 0.0 0.56 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EON98500.1 - 7.9e-05 22.1 0.0 0.63 9.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EON98500.1 - 0.00016 21.9 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EON98500.1 - 0.00031 20.5 0.4 1.2 9.0 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EON98500.1 - 0.00047 18.8 5.6 0.0042 15.7 0.0 3.0 4 0 0 4 4 4 1 Predicted ATPase of the ABC class DUF87 PF01935.12 EON98500.1 - 0.00054 19.8 2.3 0.45 10.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EON98500.1 - 0.00058 19.0 0.1 0.46 9.5 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin APS_kinase PF01583.15 EON98500.1 - 0.0009 18.9 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.9 EON98500.1 - 0.0012 18.5 0.0 5.4 6.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 EON98500.1 - 0.0017 17.0 4.6 0.093 11.2 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 EON98500.1 - 0.0031 17.4 0.0 1.4 8.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EON98500.1 - 0.012 15.5 0.0 5.2 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EON98500.1 - 0.019 15.1 0.1 65 3.7 0.0 4.3 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EON98500.1 - 0.026 13.2 2.8 4 6.0 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit MobB PF03205.9 EON98500.1 - 0.029 14.0 0.0 7.5 6.2 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 EON98500.1 - 0.052 12.9 0.0 9.4 5.5 0.0 2.9 3 0 0 3 3 2 0 Thymidylate kinase NB-ARC PF00931.17 EON98500.1 - 0.062 12.1 0.0 9.4 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 EON98500.1 - 0.1 12.1 0.5 8 5.9 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EON98500.1 - 0.13 12.4 0.0 8.4 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Sugar_tr PF00083.19 EON98501.1 - 1.9e-34 119.0 12.7 2.2e-34 118.8 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98501.1 - 9.9e-09 34.3 12.9 1.3e-08 33.9 9.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF543 PF04418.7 EON98501.1 - 0.15 12.0 0.5 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) adh_short PF00106.20 EON98502.1 - 1.6e-12 47.6 0.0 4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98502.1 - 4.1e-07 29.8 0.0 7.5e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EON98502.1 - 6.6e-07 29.3 0.1 1e-06 28.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EON98502.1 - 1.5e-05 24.5 0.1 3.2e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EON98502.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GST_C_2 PF13410.1 EON98503.1 - 9.7e-15 54.2 0.2 2.6e-14 52.8 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EON98503.1 - 3.4e-12 46.1 0.0 7.7e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EON98503.1 - 5.5e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EON98503.1 - 0.00052 20.4 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.6 EON98504.1 - 3.1e-18 65.0 0.1 1.2e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain FAD_binding_3 PF01494.14 EON98504.1 - 1.8e-12 47.0 0.1 9.2e-10 38.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Cupin_3 PF05899.7 EON98504.1 - 0.044 13.1 0.0 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CENP-C_C PF11699.3 EON98504.1 - 0.077 12.9 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Mif2/CENP-C like Sugar_tr PF00083.19 EON98505.1 - 2.1e-84 283.7 21.5 2.4e-84 283.5 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98505.1 - 4.5e-18 65.0 27.2 8.8e-18 64.1 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON98505.1 - 2e-07 29.8 20.1 0.00015 20.3 4.1 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 EON98505.1 - 9.3e-06 24.4 2.2 2.1e-05 23.2 1.6 1.5 1 1 0 1 1 1 1 Reduced folate carrier Acetyltransf_3 PF13302.1 EON98506.1 - 3.7e-31 108.2 0.0 1.6e-30 106.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON98506.1 - 2.7e-06 27.3 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EON98506.1 - 7.8e-05 22.5 0.0 9.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 EON98507.1 - 1.3e-23 83.6 0.0 2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EON98507.1 - 6.9e-21 74.5 0.0 2.2e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EON98507.1 - 6.7e-08 32.4 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON98507.1 - 0.00079 19.3 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EON98507.1 - 0.0035 16.5 0.7 0.011 14.9 0.5 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EON98507.1 - 0.036 12.6 0.0 0.2 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 EON98507.1 - 0.062 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_61 PF03443.9 EON98508.1 - 3.4e-67 226.4 1.0 4e-67 226.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrolase_6 PF13344.1 EON98509.1 - 6.7e-23 80.4 0.0 1.5e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EON98509.1 - 8.9e-19 66.9 0.0 3.4e-18 65.1 0.0 2.0 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EON98509.1 - 0.0003 21.0 0.2 0.14 12.3 0.0 3.0 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON98509.1 - 0.003 18.0 0.0 0.086 13.2 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EON98509.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.16 EON98510.1 - 1.7e-56 191.1 0.0 2e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.16 EON98511.1 - 6.8e-21 74.2 0.0 8.2e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 EON98512.1 - 2.7e-19 69.1 28.2 4.6e-18 65.0 10.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1228 PF06779.9 EON98512.1 - 0.14 12.1 0.1 0.14 12.1 0.0 2.7 3 2 0 3 3 3 0 Protein of unknown function (DUF1228) Beta-lactamase PF00144.19 EON98513.1 - 2.4e-46 158.2 0.0 3.4e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EON98513.1 - 0.00018 21.0 0.0 0.42 10.0 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.15 EON98513.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase ADH_zinc_N PF00107.21 EON98514.1 - 6.1e-28 96.9 0.1 9.7e-28 96.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON98514.1 - 1.8e-13 51.4 0.7 3.6e-13 50.5 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98514.1 - 3.1e-11 42.9 0.0 2.2e-10 40.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.6 EON98514.1 - 0.07 12.6 1.1 15 5.1 0.0 3.5 4 0 0 4 4 4 0 Cupin domain Peptidase_M50B PF13398.1 EON98515.1 - 4.4e-56 189.4 16.3 5.6e-56 189.1 11.3 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EON98515.1 - 0.00052 19.0 0.1 0.00052 19.0 0.1 2.6 3 1 0 3 3 3 1 Peptidase family M50 YlaC PF10777.4 EON98515.1 - 0.053 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Inner membrane protein YlaC BTP PF05232.7 EON98515.1 - 3 7.6 10.4 1.3 8.8 0.2 2.8 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Alpha-amylase PF00128.19 EON98516.1 - 4.2e-96 322.0 0.1 7.4e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EON98516.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EON98517.1 - 3.1e-73 246.9 25.8 1.2e-43 149.3 7.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON98517.1 - 5.4e-09 35.2 11.4 5.4e-09 35.2 7.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON98517.1 - 0.0013 17.1 21.4 0.019 13.4 1.8 2.5 1 1 0 2 2 2 2 MFS/sugar transport protein Cu-oxidase PF00394.17 EON98518.1 - 4.8e-38 130.5 2.6 2.4e-35 121.7 0.3 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EON98518.1 - 1.7e-32 111.8 0.6 1e-29 102.8 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EON98518.1 - 8.1e-21 73.9 1.9 3.4e-19 68.7 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase V-ATPase_G PF03179.10 EON98519.1 - 6.5e-34 116.3 18.8 7.6e-34 116.1 13.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EON98519.1 - 0.0033 17.2 9.5 0.0033 17.2 6.6 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EON98519.1 - 0.0065 15.7 11.4 0.0065 15.7 7.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) FRD2 PF03197.8 EON98519.1 - 0.06 13.9 1.3 0.074 13.6 0.9 1.2 1 0 0 1 1 1 0 Bacteriophage FRD2 protein DUF4604 PF15377.1 EON98519.1 - 0.097 12.8 15.6 0.12 12.5 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF1777 PF08648.7 EON98519.1 - 0.11 12.2 6.4 0.13 12.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Vfa1 PF08432.5 EON98519.1 - 0.11 12.4 15.8 0.13 12.3 11.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRF PF01765.14 EON98519.1 - 0.12 11.8 14.8 0.19 11.1 10.3 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF2482 PF10655.4 EON98519.1 - 0.12 12.4 1.4 2.8 8.0 0.6 2.0 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Nop25 PF09805.4 EON98519.1 - 0.14 12.2 16.9 0.18 11.8 11.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2203 PF09969.4 EON98519.1 - 0.18 12.0 4.5 0.25 11.5 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF87 PF01935.12 EON98519.1 - 0.24 11.2 3.2 0.26 11.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 OmpH PF03938.9 EON98519.1 - 0.49 10.3 13.0 0.61 10.0 9.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2201_N PF13203.1 EON98519.1 - 0.51 9.4 6.0 0.57 9.2 4.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP11 PF06644.6 EON98519.1 - 0.52 9.7 10.0 0.66 9.4 6.9 1.1 1 0 0 1 1 1 0 ATP11 protein DUF3435 PF11917.3 EON98519.1 - 0.78 8.3 5.5 0.94 8.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) YusW PF14039.1 EON98519.1 - 0.82 9.9 8.2 1 9.6 5.4 1.4 1 1 0 1 1 1 0 YusW-like protein Ycf1 PF05758.7 EON98519.1 - 1.3 6.5 10.8 1.5 6.4 7.5 1.0 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 EON98519.1 - 1.4 8.3 11.0 1.7 8.1 7.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SAPS PF04499.10 EON98519.1 - 1.9 7.0 8.2 2.1 6.8 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HrpE PF06188.7 EON98519.1 - 2.1 8.0 9.4 3 7.5 1.4 2.0 1 1 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E vATP-synt_E PF01991.13 EON98519.1 - 2.5 7.3 22.3 1.4 8.1 7.8 2.3 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Potyvirid-P3 PF13608.1 EON98519.1 - 3.8 6.5 7.2 4.5 6.2 5.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein MRP-S26 PF14943.1 EON98519.1 - 4.1 6.9 18.3 0.28 10.6 6.5 2.0 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 ELH PF02323.10 EON98520.1 - 0.03 13.4 5.6 0.04 13.0 3.9 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor ICL PF00463.16 EON98521.1 - 3e-94 316.1 0.1 3.5e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DSBA PF01323.15 EON98522.1 - 7.6e-36 123.4 0.0 8.6e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EON98522.1 - 0.011 15.5 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EON98522.1 - 0.041 13.8 0.0 0.097 12.6 0.0 1.6 2 1 0 2 2 2 0 Thioredoxin CcmH PF03918.9 EON98522.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein RNA_pol_Rpb2_6 PF00562.23 EON98523.1 - 1.6e-125 418.8 0.1 5.3e-125 417.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EON98523.1 - 2.7e-55 186.4 0.0 4.1e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EON98523.1 - 3.1e-48 163.7 0.1 6.3e-48 162.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EON98523.1 - 1e-29 102.6 0.0 2.6e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EON98523.1 - 5.9e-23 80.5 0.8 1.5e-22 79.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EON98523.1 - 8.8e-23 79.8 0.0 1.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EON98523.1 - 8.9e-23 79.8 0.2 2.5e-22 78.4 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 adh_short PF00106.20 EON98524.1 - 1.4e-11 44.6 0.0 2.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98524.1 - 7.3e-06 25.7 0.0 2e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Glyco_transf_36 PF06165.6 EON98525.1 - 9.3e-20 70.5 0.0 1.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 DUF608 PF04685.8 EON98525.1 - 0.011 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 EON98525.1 - 0.02 13.0 0.0 0.031 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase GT36_AF PF06205.6 EON98525.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase 36 associated family DUF1479 PF07350.7 EON98526.1 - 2.5e-158 526.9 0.0 3e-158 526.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Reprolysin_4 PF13583.1 EON98527.1 - 9.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EON98527.1 - 0.00078 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EON98527.1 - 0.002 18.1 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EON98527.1 - 0.0091 15.7 0.6 0.013 15.1 0.4 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 EON98527.1 - 0.03 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EON98527.1 - 0.033 13.0 0.1 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 EON98527.1 - 0.084 12.4 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Astacin PF01400.19 EON98527.1 - 0.2 11.0 0.5 0.27 10.5 0.3 1.4 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) RRM_1 PF00076.17 EON98528.1 - 4.4e-64 212.0 2.2 2.2e-15 56.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98528.1 - 3.4e-56 187.1 0.2 1.5e-12 47.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98528.1 - 3.5e-26 90.8 0.0 1.6e-07 31.0 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EON98528.1 - 8.6e-07 28.6 0.1 0.095 12.4 0.0 4.5 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EON98528.1 - 3.5e-06 26.6 0.0 0.74 9.6 0.0 4.5 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EON98528.1 - 0.00011 21.9 0.1 0.31 10.8 0.0 4.2 4 0 0 4 4 4 1 RNA binding motif tRNA-synt_2 PF00152.15 EON98529.1 - 1.1e-68 231.5 0.0 3.1e-68 230.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EON98529.1 - 2.1e-10 40.3 0.0 3.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EON98529.1 - 0.00082 18.6 0.0 0.1 11.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EON98529.1 - 0.035 13.6 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_S8 PF00082.17 EON98530.1 - 5.1e-33 114.4 0.0 7.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family AAA_18 PF13238.1 EON98532.1 - 6.3e-10 39.4 0.0 9.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EON98532.1 - 0.00023 21.0 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.1 EON98532.1 - 0.00043 21.0 0.0 0.00068 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EON98532.1 - 0.00064 19.6 0.0 0.00084 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EON98532.1 - 0.0019 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EON98532.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 EON98532.1 - 0.046 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Thymidylate_kin PF02223.12 EON98532.1 - 0.073 12.4 0.2 4 6.7 0.1 2.4 2 1 0 2 2 2 0 Thymidylate kinase adh_short PF00106.20 EON98533.1 - 8.7e-24 84.3 9.2 1.3e-23 83.7 6.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98533.1 - 8.5e-09 35.5 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EON98533.1 - 1.1e-07 32.0 2.8 3.9e-07 30.2 1.9 1.8 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EON98533.1 - 2.2e-07 30.6 5.6 5e-07 29.5 3.8 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EON98533.1 - 1.4e-06 27.2 0.0 2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EON98533.1 - 0.04 13.3 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Herpes_UL87 PF03043.9 EON98533.1 - 0.13 10.6 0.1 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family NmrA PF05368.8 EON98534.1 - 3.2e-62 209.8 0.0 4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98534.1 - 2.4e-14 53.7 0.0 3.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EON98534.1 - 4e-05 22.4 0.1 5.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EON98534.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 EON98535.1 - 2.5e-15 56.0 6.5 2.1e-09 36.4 0.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Bac_export_1 PF01311.15 EON98535.1 - 0.13 11.4 1.4 0.29 10.3 0.1 2.0 1 1 2 3 3 3 0 Bacterial export proteins, family 1 zf-Tim10_DDP PF02953.10 EON98536.1 - 3.4e-20 71.0 0.4 4.1e-20 70.8 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GATA PF00320.22 EON98537.1 - 4.4e-16 57.9 4.9 9.9e-16 56.7 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EON98537.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EON98537.1 - 2.8e-10 40.4 0.0 1.4e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EON98537.1 - 5.2e-09 35.8 0.1 1.4e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 EON98537.1 - 1.5e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EON98537.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold APC2 PF08672.6 EON98537.1 - 0.08 13.2 0.0 9.1 6.6 0.0 2.6 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 5_3_exonuc_N PF02739.11 EON98537.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain TF_Zn_Ribbon PF08271.7 EON98537.1 - 0.16 11.2 0.6 1 8.7 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 EON98537.1 - 2.3 8.0 5.6 0.6 9.8 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Pkinase PF00069.20 EON98538.1 - 2.3e-64 217.0 0.0 4.3e-64 216.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98538.1 - 8.6e-37 126.6 0.0 6e-34 117.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON98538.1 - 9e-06 24.8 0.1 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EON98538.1 - 0.00053 19.7 0.1 0.0026 17.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EON98538.1 - 0.0059 15.6 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EON98538.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family zf-H2C2_2 PF13465.1 EON98539.1 - 1.8e-05 24.7 9.0 0.0023 18.1 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EON98539.1 - 0.00053 20.1 8.9 0.05 13.9 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EON98539.1 - 0.00058 19.9 3.1 0.021 14.9 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EON98539.1 - 0.018 15.3 14.4 0.12 12.7 1.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EON98539.1 - 0.023 14.5 0.8 0.023 14.5 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.27 EON98540.1 - 0.00035 20.3 0.0 0.2 11.6 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Na_Ca_ex PF01699.19 EON98541.1 - 2e-39 134.4 32.9 6e-22 77.7 11.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rax2 PF12768.2 EON98541.1 - 0.6 9.2 3.6 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SET PF00856.23 EON98543.1 - 1.1e-19 71.3 0.1 1.1e-19 71.3 0.1 3.0 3 1 0 3 3 3 1 SET domain DUF592 PF04574.8 EON98543.1 - 0.021 14.3 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) Kelch_4 PF13418.1 EON98544.1 - 3.1e-26 90.8 11.8 7.2e-09 35.2 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EON98544.1 - 3.8e-23 80.6 3.3 4.1e-05 23.5 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EON98544.1 - 5.3e-23 80.5 8.2 5.9e-07 29.3 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EON98544.1 - 3.4e-22 78.0 2.9 9.3e-08 32.0 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EON98544.1 - 1.1e-21 76.0 0.3 9e-05 21.9 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EON98544.1 - 4.9e-17 60.9 5.7 0.0014 18.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EON98544.1 - 4.1e-09 36.4 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PPP4R2 PF09184.6 EON98545.1 - 6.2e-08 32.5 0.0 6.2e-08 32.5 0.0 2.8 3 0 0 3 3 3 1 PPP4R2 FAD-oxidase_C PF02913.14 EON98546.1 - 4.7e-58 196.4 0.5 9.6e-58 195.4 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EON98546.1 - 3.2e-36 123.8 0.1 6.1e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Transp_cyt_pur PF02133.10 EON98547.1 - 2.1e-46 158.3 27.2 2.7e-46 158.0 18.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3752 PF12572.3 EON98548.1 - 4e-42 143.9 6.1 5.1e-42 143.5 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) MelC1 PF06236.6 EON98548.1 - 3 7.8 8.0 0.3 11.0 2.6 1.5 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Kelch_4 PF13418.1 EON98549.1 - 2.6e-44 148.7 21.2 7e-10 38.5 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EON98549.1 - 2.9e-43 145.0 25.5 6.7e-10 38.8 0.0 7.8 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EON98549.1 - 7.2e-40 134.3 17.6 1.8e-06 27.7 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.20 EON98549.1 - 1.3e-39 133.4 16.2 4.7e-08 32.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EON98549.1 - 3.7e-35 118.6 16.2 1.5e-06 28.0 0.0 7.0 5 2 2 7 7 7 6 Kelch motif Kelch_2 PF07646.10 EON98549.1 - 1.6e-31 106.8 14.9 1.4e-07 31.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Dus PF01207.12 EON98551.1 - 1.5e-37 129.1 0.0 4.6e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DEAD PF00270.24 EON98552.1 - 1.8e-27 95.9 0.1 2.9e-15 56.1 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EON98552.1 - 2.6e-22 78.4 0.1 1.3e-21 76.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON98552.1 - 0.00097 19.0 0.1 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fil_haemagg PF05594.9 EON98553.1 - 0.11 12.7 1.8 0.22 11.8 1.2 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat ATP-synt_G PF04718.10 EON98555.1 - 8.9e-28 96.9 0.6 2.3e-27 95.6 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF1275 PF06912.6 EON98555.1 - 0.034 13.3 0.3 0.057 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) SPRY PF00622.23 EON98556.1 - 0.00076 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Glyco_tranf_2_3 PF13641.1 EON98557.1 - 1.3e-18 67.6 0.0 1.5e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EON98557.1 - 3e-08 33.5 0.0 1.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EON98557.1 - 1.1e-05 24.8 0.0 2.5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 PH_6 PF15406.1 EON98558.1 - 9.2e-42 141.6 1.6 9.2e-42 141.6 1.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EON98558.1 - 0.0013 18.9 0.0 0.0041 17.2 0.0 1.9 1 0 0 1 1 1 1 PH domain HATPase_c PF02518.21 EON98559.1 - 4.8e-23 81.0 0.1 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EON98559.1 - 2.8e-18 65.9 0.1 6.4e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EON98559.1 - 4e-08 33.1 0.0 9.8e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EON98559.1 - 9.5e-08 32.3 0.0 2.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EON98559.1 - 4e-05 23.3 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EON98559.1 - 0.00067 19.7 0.5 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EON98559.1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold FAM195 PF14799.1 EON98559.1 - 0.15 11.9 2.7 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 FAM195 family Amidase PF01425.16 EON98560.1 - 2.3e-57 194.8 0.0 2.9e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EON98561.1 - 2.7e-17 63.2 0.0 3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family 4F5 PF04419.9 EON98562.1 - 5.2e-08 33.4 10.7 9.3e-08 32.6 7.4 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 EON98562.1 - 2.2e-05 24.2 0.5 4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding Baculo_ME53 PF06061.6 EON98562.1 - 0.01 14.8 0.3 0.012 14.6 0.2 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 HypA PF01155.14 EON98562.1 - 0.1 12.3 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family HHH PF00633.18 EON98563.1 - 0.00098 18.6 0.1 0.0026 17.3 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif zf-RING_2 PF13639.1 EON98564.1 - 4.6e-13 48.7 7.0 7.5e-13 48.0 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EON98564.1 - 6e-08 32.2 3.8 9.8e-08 31.5 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EON98564.1 - 2.6e-07 30.6 4.8 5.3e-07 29.6 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EON98564.1 - 1.4e-05 24.7 4.0 2.2e-05 24.0 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EON98564.1 - 2.6e-05 24.1 5.6 4.3e-05 23.4 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON98564.1 - 5.3e-05 22.7 2.6 8e-05 22.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EON98564.1 - 0.0014 18.4 2.6 0.0032 17.2 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EON98564.1 - 0.0092 15.5 6.3 0.016 14.8 4.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 EON98564.1 - 0.14 11.8 5.8 0.25 11.0 4.0 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EON98564.1 - 0.34 10.8 3.2 0.91 9.5 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EON98564.1 - 0.49 10.3 4.7 1 9.2 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EON98564.1 - 3.5 7.4 9.3 20 5.0 6.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EON98564.1 - 7 6.7 7.9 3.6 7.6 3.8 1.8 2 0 0 2 2 2 0 RING-variant domain TFIIA PF03153.8 EON98565.1 - 3.1e-85 287.3 8.1 3.6e-85 287.1 5.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit YL1 PF05764.8 EON98565.1 - 5.1e-05 23.0 2.0 8.6e-05 22.2 1.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein DUF3295 PF11702.3 EON98565.1 - 0.00027 20.0 0.1 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF2457 PF10446.4 EON98565.1 - 0.043 12.5 9.0 0.074 11.7 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 EON98565.1 - 0.048 13.3 4.4 0.075 12.7 3.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EON98565.1 - 0.085 10.7 6.9 0.1 10.4 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family EBV-NA3 PF05009.7 EON98565.1 - 0.91 8.7 3.5 1.6 7.9 2.4 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sigma70_ner PF04546.8 EON98565.1 - 1.1 8.7 6.3 2.2 7.8 4.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C4H2 PF10146.4 EON98565.1 - 7.5 6.5 6.0 6.3 6.7 1.8 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein XPG_N PF00752.12 EON98566.1 - 2.9e-32 110.9 0.0 6.6e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EON98566.1 - 7.5e-27 93.2 0.0 2e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EON98566.1 - 0.0016 17.8 0.6 0.023 14.2 0.4 3.2 1 0 0 1 1 1 1 Ubiquitin interaction motif Ly49 PF08391.5 EON98566.1 - 0.33 11.0 2.5 1.6 8.9 1.8 2.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TEA PF01285.13 EON98568.1 - 2e-15 56.8 0.1 2e-15 56.8 0.1 2.2 2 1 0 2 2 2 1 TEA/ATTS domain family PAT1 PF09770.4 EON98568.1 - 3 5.9 19.3 4.8 5.2 13.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 EON98568.1 - 7.9 6.5 10.2 21 5.1 7.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bap31 PF05529.7 EON98570.1 - 3.3e-66 222.4 5.9 3.7e-66 222.2 4.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like IncA PF04156.9 EON98570.1 - 0.11 12.1 0.5 0.24 10.9 0.3 1.6 1 0 0 1 1 1 0 IncA protein PEP-utilisers_N PF05524.8 EON98570.1 - 0.11 12.2 0.5 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DivIC PF04977.10 EON98570.1 - 0.18 11.3 8.3 0.27 10.7 1.0 3.5 4 0 0 4 4 4 0 Septum formation initiator Spt5_N PF11942.3 EON98570.1 - 1.1 9.9 4.0 2.2 8.9 2.8 1.6 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TMF_DNA_bd PF12329.3 EON98570.1 - 1.1 9.1 8.7 0.086 12.6 1.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 EON98570.1 - 1.2 7.9 4.2 0.56 9.1 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1971 PF09313.6 EON98571.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) PsbI PF02532.9 EON98571.1 - 0.16 11.6 3.2 0.17 11.5 0.5 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF2897 PF11446.3 EON98571.1 - 0.77 9.6 2.5 2.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) 2OG-FeII_Oxy PF03171.15 EON98573.1 - 5.4e-15 55.4 0.0 9.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Suppressor_APC PF11414.3 EON98573.1 - 0.12 12.2 0.3 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein PG_binding_1 PF01471.13 EON98574.1 - 3.9e-05 23.5 3.6 0.0054 16.6 0.1 3.1 3 0 0 3 3 3 2 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.2 EON98574.1 - 0.0027 17.5 3.4 0.0027 17.5 2.4 2.3 2 1 0 2 2 2 1 Tropomyosin like Laminin_II PF06009.7 EON98574.1 - 0.0095 15.6 1.7 0.027 14.2 1.2 1.8 1 0 0 1 1 1 1 Laminin Domain II ATG16 PF08614.6 EON98574.1 - 0.013 15.3 2.5 0.033 13.9 1.7 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EON98574.1 - 0.018 13.7 2.9 0.036 12.7 2.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 EON98574.1 - 0.044 12.2 2.3 0.084 11.3 1.6 1.3 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EON98574.1 - 0.064 12.4 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 EON98574.1 - 0.12 11.3 4.3 0.24 10.3 3.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 EON98574.1 - 0.59 10.5 7.2 2.4 8.5 0.8 2.7 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EON98574.1 - 0.83 9.2 4.6 2.2 7.8 3.2 1.7 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EON98574.1 - 1 9.4 3.0 3.5 7.7 1.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SUR7 PF06687.7 EON98575.1 - 6.6e-36 123.8 15.2 7.9e-36 123.6 10.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.1 EON98575.1 - 0.0071 16.4 1.6 0.0071 16.4 1.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) Aldedh PF00171.17 EON98576.1 - 6.3e-131 436.8 0.0 7e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.23 EON98577.1 - 2.6e-39 134.7 0.2 3.3e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EON98578.1 - 5e-25 86.4 17.3 1.7e-06 27.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EON98578.1 - 2.5e-06 27.3 0.2 0.00011 21.9 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EON98578.1 - 0.026 14.0 0.0 0.55 9.7 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pil1 PF13805.1 EON98580.1 - 1.2e-153 509.9 0.2 1.4e-153 509.7 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EON98580.1 - 0.024 13.9 2.4 0.033 13.5 0.8 1.7 1 1 0 1 1 1 0 FAM92 protein NOA36 PF06524.7 EON98580.1 - 0.26 10.5 3.3 0.45 9.7 2.3 1.3 1 0 0 1 1 1 0 NOA36 protein HIG_1_N PF04588.8 EON98581.1 - 8.3e-08 31.8 3.1 8.3e-08 31.8 2.1 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region TauE PF01925.14 EON98581.1 - 0.17 11.3 7.1 0.068 12.6 0.7 2.2 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE CLTH PF10607.4 EON98582.1 - 7.2e-30 103.5 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EON98582.1 - 3.1e-18 65.2 0.5 6e-18 64.2 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EON98582.1 - 0.00011 21.4 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EON98582.1 - 0.00018 21.2 0.3 0.0003 20.5 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EON98582.1 - 0.00096 18.8 0.2 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Flagellin_C PF00700.16 EON98582.1 - 0.0013 18.8 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region zf-C3HC4_2 PF13923.1 EON98582.1 - 0.0028 17.6 0.5 0.0048 16.8 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON98582.1 - 0.0059 16.2 0.4 0.01 15.4 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON98582.1 - 0.0086 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EON98582.1 - 0.081 12.8 0.7 0.16 11.9 0.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ECH PF00378.15 EON98584.1 - 1.9e-38 132.0 0.0 2.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NAD_binding_8 PF13450.1 EON98585.1 - 2.8e-06 27.2 0.0 4.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON98585.1 - 1.9e-05 24.8 0.0 0.0054 16.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lipoprotein_18 PF06804.6 EON98585.1 - 0.018 13.8 0.0 0.022 13.5 0.0 1.0 1 0 0 1 1 1 0 NlpB/DapX lipoprotein NAD_binding_9 PF13454.1 EON98585.1 - 0.021 14.6 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ADH_N PF08240.7 EON98587.1 - 7.8e-27 93.1 1.2 1.9e-26 91.9 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON98587.1 - 1.1e-14 54.0 0.1 1.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 EON98587.1 - 0.015 15.0 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 S1-like Aldedh PF00171.17 EON98588.1 - 2.1e-163 543.9 0.8 2.3e-163 543.8 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EON98588.1 - 0.0046 16.2 0.0 0.017 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pro_isomerase PF00160.16 EON98589.1 - 2.6e-48 164.1 0.3 2.9e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EON98589.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain 7TM_GPCR_Str PF10326.4 EON98591.1 - 0.044 12.9 6.8 0.017 14.2 2.7 1.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str MARVEL PF01284.18 EON98591.1 - 1.8 8.3 8.2 0.62 9.8 2.7 2.1 2 0 0 2 2 2 0 Membrane-associating domain PetM PF08041.6 EON98591.1 - 7.9 6.0 7.7 2.2 7.8 0.3 2.5 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 tRNA-synt_1 PF00133.17 EON98592.1 - 2.3e-154 514.7 0.0 3.1e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EON98592.1 - 4.1e-22 78.3 0.0 2.5e-13 49.4 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EON98592.1 - 5.8e-18 65.0 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EON98592.1 - 0.00066 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EON98592.1 - 0.0032 16.6 0.0 0.77 8.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain AAA_23 PF13476.1 EON98593.1 - 3e-26 93.0 2.6 3e-26 93.0 1.8 7.9 1 1 5 6 6 6 1 AAA domain SbcCD_C PF13558.1 EON98593.1 - 7e-11 41.8 0.1 4.6e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EON98593.1 - 1.6e-07 30.2 122.0 0.0025 16.3 0.0 6.3 2 1 4 6 6 6 5 AAA domain SMC_N PF02463.14 EON98593.1 - 1e-06 28.1 0.0 1e-06 28.1 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EON98593.1 - 1.8e-06 28.1 17.3 0.0002 21.4 1.1 4.0 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EON98593.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain COG2 PF06148.6 EON98593.1 - 0.0066 16.3 1.4 0.0066 16.3 1.0 9.6 5 2 3 8 8 8 3 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.11 EON98593.1 - 0.035 14.1 0.4 0.035 14.1 0.3 9.6 4 3 4 10 10 10 0 Flagellar FliJ protein ABC_tran PF00005.22 EON98593.1 - 0.068 13.4 0.0 0.068 13.4 0.0 7.2 4 2 1 5 5 5 0 ABC transporter adh_short PF00106.20 EON98594.1 - 1.4e-08 34.8 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EON98594.1 - 2.7e-05 23.7 0.0 2.9e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EON98594.1 - 0.00017 21.4 0.1 0.00019 21.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EON98594.1 - 0.0046 16.9 0.0 0.0048 16.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EON98594.1 - 0.02 14.5 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 KR domain RRF PF01765.14 EON98595.1 - 4.9e-25 87.8 3.0 6.1e-25 87.6 2.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor GvpL_GvpF PF06386.6 EON98595.1 - 0.006 16.2 1.6 0.0092 15.5 1.1 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF DUF733 PF05306.6 EON98595.1 - 0.092 13.0 3.2 0.21 11.8 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF733) XH PF03469.9 EON98595.1 - 0.099 12.2 4.4 0.35 10.5 2.5 2.0 2 0 0 2 2 2 0 XH domain EspA PF03433.8 EON98596.1 - 0.25 10.7 3.3 0.12 11.8 0.7 1.6 2 0 0 2 2 2 0 EspA-like secreted protein Peroxin-13_N PF04088.8 EON98597.1 - 6.2e-59 198.4 0.0 1.1e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EON98597.1 - 4.4e-08 32.4 0.0 9e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EON98597.1 - 8.2e-07 28.3 0.0 2.3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON98597.1 - 5.4e-06 25.8 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dynein_light PF01221.13 EON98598.1 - 3.7e-41 139.0 1.2 4.2e-41 138.8 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 EON98598.1 - 0.073 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 28 Epimerase PF01370.16 EON98599.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RNA_pol_N PF01194.12 EON98600.1 - 3.6e-29 100.5 2.4 4.3e-29 100.3 1.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Corona_5a PF06336.6 EON98600.1 - 0.13 12.2 0.2 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Coronavirus 5a protein Ank_2 PF12796.2 EON98601.1 - 2e-23 82.5 3.2 3.1e-10 40.2 0.2 4.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EON98601.1 - 4.7e-20 70.3 11.0 0.00012 21.6 0.2 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EON98601.1 - 4.5e-18 64.8 12.1 2.2e-08 34.0 0.6 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON98601.1 - 1.7e-17 63.4 8.7 1e-06 29.1 0.3 6.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON98601.1 - 4.7e-12 44.9 7.6 0.15 12.3 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Mitofilin PF09731.4 EON98602.1 - 0.15 10.7 47.3 0.058 12.0 20.5 2.3 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF236 PF03057.9 EON98602.1 - 0.16 11.8 1.6 1 9.3 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function NAD_binding_4 PF07993.7 EON98603.1 - 3e-23 82.0 0.0 4.3e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EON98603.1 - 1.7e-07 30.9 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EON98603.1 - 0.00011 22.3 0.0 0.00036 20.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site VCBS PF13517.1 EON98604.1 - 3.6e-27 94.5 57.6 2e-11 44.1 1.1 8.8 3 2 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EON98604.1 - 4.7e-15 54.7 42.0 0.0031 17.1 0.1 8.2 8 0 0 8 8 8 5 FG-GAP repeat Lipase_GDSL PF00657.17 EON98604.1 - 8.2e-12 45.4 0.1 1.4e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 EON98604.1 - 1.4e-09 37.6 13.9 0.12 11.7 0.1 7.1 4 3 3 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region CENP-B_N PF04218.8 EON98605.1 - 0.01 15.2 0.1 0.9 9.0 0.0 2.9 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain DUF4443 PF14544.1 EON98605.1 - 0.27 11.1 2.7 16 5.4 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4443) AA_permease PF00324.16 EON98606.1 - 5.4e-101 338.2 28.7 6.4e-101 338.0 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON98606.1 - 7.8e-21 74.1 27.2 1e-20 73.7 18.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EON98606.1 - 0.005 16.5 0.3 0.005 16.5 0.2 3.3 4 1 0 4 4 4 2 Domain of unknown function (DUF1772) MMR_HSR1 PF01926.18 EON98607.1 - 1.2e-17 63.9 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EON98607.1 - 6e-08 32.1 0.0 1.1e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Adenylsucc_synt PF00709.16 EON98608.1 - 4.3e-76 256.2 0.0 6.9e-38 130.3 0.1 2.6 1 1 1 2 2 2 2 Adenylosuccinate synthetase MFS_1 PF07690.11 EON98609.1 - 6e-41 140.3 30.0 6e-41 140.3 20.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EON98609.1 - 0.00016 21.2 3.2 0.00055 19.4 2.2 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Cytadhesin_P30 PF07271.6 EON98609.1 - 0.022 14.0 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Lactamase_B PF00753.22 EON98610.1 - 3.5e-28 98.5 1.6 5.2e-28 98.0 1.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EON98610.1 - 1.4e-07 31.2 0.1 1.7e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EON98610.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HGTP_anticodon2 PF12745.2 EON98611.1 - 8.7e-73 244.8 2.1 8.7e-73 244.8 1.4 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EON98611.1 - 1.3e-37 129.3 9.9 1.3e-20 73.6 0.0 5.8 5 2 1 6 6 6 3 Protein kinase domain Pkinase_Tyr PF07714.12 EON98611.1 - 7.9e-23 80.8 0.0 3.1e-11 42.8 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EON98611.1 - 1.6e-15 56.9 0.0 1.6e-15 56.9 0.0 2.4 3 0 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.17 EON98611.1 - 6.3e-14 51.8 0.2 2e-13 50.2 0.1 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.18 EON98611.1 - 0.06 13.0 2.5 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L31 PF01197.13 EON98612.1 - 0.0026 17.6 0.2 0.0056 16.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L31 PTR2 PF00854.16 EON98614.1 - 5.7e-48 163.5 7.5 4.8e-47 160.5 5.2 2.2 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EON98614.1 - 2.9e-07 29.5 20.7 6.4e-07 28.4 12.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-DHHC PF01529.15 EON98615.1 - 8.9e-42 142.4 3.6 1.8e-41 141.4 2.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EON98615.1 - 0.025 14.0 0.8 0.025 14.0 0.6 2.1 2 0 0 2 2 2 0 Yip1 domain DZR PF12773.2 EON98615.1 - 5.4 6.9 13.1 0.31 10.8 4.8 2.0 2 0 0 2 2 2 0 Double zinc ribbon DUF922 PF06037.6 EON98617.1 - 0.014 14.7 0.3 0.026 13.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) MFS_1 PF07690.11 EON98618.1 - 1e-42 146.1 55.0 1.1e-41 142.7 38.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON98618.1 - 1.4e-09 36.7 16.6 1.4e-09 36.7 11.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ycf1 PF05758.7 EON98618.1 - 0.0053 14.5 0.4 0.0053 14.5 0.3 1.4 2 0 0 2 2 2 1 Ycf1 WTF PF03303.8 EON98618.1 - 1 8.7 6.6 2.7 7.3 4.3 1.8 2 0 0 2 2 2 0 WTF protein polyprenyl_synt PF00348.12 EON98619.1 - 2.1e-71 239.8 0.0 2.5e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase TFIIE-A_C-term PF11521.3 EON98621.1 - 0.26 11.2 4.8 0.58 10.1 3.3 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Fungal_trans PF04082.13 EON98623.1 - 1.7e-21 76.2 0.1 2.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON98623.1 - 5.9e-09 35.6 8.0 9.4e-09 35.0 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCD14 PF08704.5 EON98624.1 - 3.1e-61 207.0 0.7 2.7e-47 161.3 0.0 3.9 4 1 0 4 4 4 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EON98624.1 - 3.9e-05 24.1 0.0 0.00028 21.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON98624.1 - 0.00045 20.2 0.0 0.00098 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain U79_P34 PF03064.11 EON98624.1 - 6.2 6.2 15.1 0.48 9.9 4.3 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 FLILHELTA PF10306.4 EON98625.1 - 4.3e-29 100.3 0.0 6.8e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EON98625.1 - 0.0028 17.9 0.1 0.0044 17.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_M18 PF02127.10 EON98626.1 - 4.2e-126 420.9 0.0 4.7e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Chromo PF00385.19 EON98627.1 - 4.8e-13 48.5 7.3 1.1e-11 44.2 0.2 3.0 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EON98627.1 - 0.00027 20.7 0.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 ABC_tran PF00005.22 EON98628.1 - 7.8e-48 162.2 0.0 1.8e-26 93.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EON98628.1 - 4e-46 157.6 38.4 1.9e-26 93.1 12.0 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region MMR_HSR1 PF01926.18 EON98628.1 - 6.9e-06 26.0 0.2 0.17 11.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EON98628.1 - 7.6e-06 26.0 0.2 1.4 8.8 0.1 4.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EON98628.1 - 1.4e-05 24.5 0.6 0.042 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EON98628.1 - 3.2e-05 23.2 0.9 1.2 8.2 0.0 3.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EON98628.1 - 3.4e-05 23.9 0.1 0.098 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EON98628.1 - 4.3e-05 23.9 1.3 0.092 13.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EON98628.1 - 5.6e-05 23.9 0.5 0.41 11.4 0.4 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EON98628.1 - 7.8e-05 21.8 0.0 0.041 12.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 EON98628.1 - 0.00027 20.4 0.6 0.49 9.7 0.2 2.7 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EON98628.1 - 0.00057 19.1 3.0 0.083 12.0 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EON98628.1 - 0.00071 19.2 0.9 0.8 9.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EON98628.1 - 0.00074 18.3 2.5 0.25 10.0 0.1 2.3 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 EON98628.1 - 0.00082 19.2 3.3 0.088 12.6 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 EON98628.1 - 0.0035 16.0 0.7 0.25 9.9 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 EON98628.1 - 0.0037 16.6 0.0 0.65 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EON98628.1 - 0.0051 16.9 0.6 4.4 7.4 0.0 3.5 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EON98628.1 - 0.013 15.1 1.1 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EON98628.1 - 0.015 14.7 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EON98628.1 - 0.018 15.3 5.8 0.62 10.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 EON98628.1 - 0.018 14.8 4.5 0.083 12.7 0.3 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EON98628.1 - 0.02 15.1 0.5 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EON98628.1 - 0.05 13.5 0.7 0.27 11.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EON98628.1 - 0.11 12.0 1.8 9.8 5.6 0.2 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EON98628.1 - 0.23 11.0 1.4 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EON98628.1 - 0.43 9.5 0.0 8.7 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Fcf1 PF04900.7 EON98629.1 - 1.9e-32 111.3 1.2 1.9e-32 111.3 0.8 1.7 2 0 0 2 2 2 1 Fcf1 Cyanate_lyase PF02560.9 EON98631.1 - 1.6e-29 101.2 0.0 2.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 EON98631.1 - 5.4e-05 23.3 0.0 9.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EON98631.1 - 0.0003 20.2 0.0 0.00062 19.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.17 EON98631.1 - 0.00039 20.1 0.1 0.0006 19.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.1 EON98631.1 - 0.017 14.6 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.2 EON98631.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MKT1_C PF12246.3 EON98632.1 - 2.6e-67 226.3 0.0 3.8e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EON98632.1 - 1.4e-27 95.7 0.1 4.1e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EON98632.1 - 0.00027 21.1 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EON98632.1 - 0.0038 17.2 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 XPG I-region SPC22 PF04573.7 EON98633.1 - 6.5e-36 123.1 0.5 7e-25 87.2 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit ABC_tran PF00005.22 EON98634.1 - 1.7e-51 174.1 0.0 1.8e-29 102.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EON98634.1 - 2.1e-45 155.2 19.4 2e-21 76.6 2.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region Adaptin_binding PF10199.4 EON98634.1 - 7.9e-13 48.8 5.8 3.5e-11 43.5 4.0 2.8 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AAA_23 PF13476.1 EON98634.1 - 5.5e-09 36.6 2.8 1.5e-05 25.4 0.0 3.4 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.14 EON98634.1 - 1.5e-08 34.1 2.3 0.0087 15.3 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EON98634.1 - 7.3e-08 32.7 0.0 0.07 13.0 0.0 3.7 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EON98634.1 - 1.3e-05 24.2 0.0 0.014 14.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EON98634.1 - 1.7e-05 24.2 0.4 0.1 12.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EON98634.1 - 2.5e-05 23.8 0.0 0.068 12.6 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EON98634.1 - 5.2e-05 23.3 0.7 0.042 13.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EON98634.1 - 6.7e-05 23.0 0.2 3.5 7.7 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EON98634.1 - 0.00016 21.1 0.0 0.41 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EON98634.1 - 0.00042 21.1 0.0 1.3 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EON98634.1 - 0.00081 19.2 0.6 0.041 13.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EON98634.1 - 0.0014 18.0 0.0 0.57 9.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF258 PF03193.11 EON98634.1 - 0.0015 17.7 0.1 1 8.4 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EON98634.1 - 0.0023 17.8 0.0 0.2 11.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EON98634.1 - 0.0025 16.9 1.9 1.5 7.8 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin MobB PF03205.9 EON98634.1 - 0.0036 17.0 0.2 7.3 6.2 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EON98634.1 - 0.0044 17.5 0.1 6.8 7.2 0.1 3.2 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 EON98634.1 - 0.005 17.1 0.1 1.6 9.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EON98634.1 - 0.014 15.1 0.5 1 9.1 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EON98634.1 - 0.029 14.5 0.0 8.5 6.5 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EON98634.1 - 0.035 13.9 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EON98634.1 - 0.08 12.5 3.7 7.5 6.0 0.1 3.5 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 EON98634.1 - 0.091 12.2 0.2 5.7 6.3 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EON98634.1 - 0.13 12.4 0.1 30 4.8 0.0 3.1 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 EON98634.1 - 0.17 11.2 1.0 1.4 8.3 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WBP-1 PF11669.3 EON98634.1 - 0.4 10.7 0.5 1.2 9.2 0.3 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 TrwB_AAD_bind PF10412.4 EON98634.1 - 0.47 9.0 3.0 7.9 4.9 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF3632 PF12311.3 EON98635.1 - 1.2e-16 61.0 0.1 1.9e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Vps54 PF07928.7 EON98636.1 - 6.3e-47 159.1 0.0 1.1e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 EON98636.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Sigma70_ner PF04546.8 EON98636.1 - 3.3 7.2 13.4 0.81 9.2 6.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region TruB_N PF01509.13 EON98637.1 - 6.5e-44 149.6 0.0 1.6e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UQ_con PF00179.21 EON98638.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-MYND PF01753.13 EON98640.1 - 1.5e-07 31.1 20.7 3.9e-07 29.8 14.3 1.8 1 0 0 1 1 1 1 MYND finger Pmp3 PF01679.12 EON98641.1 - 1.3e-19 69.6 7.5 1.6e-19 69.3 5.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CoxIIa PF08113.6 EON98641.1 - 0.017 14.8 2.6 0.039 13.6 1.8 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family TctA PF01970.11 EON98641.1 - 0.22 9.8 2.0 0.26 9.6 1.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Hydantoinase_B PF02538.9 EON98642.1 - 5e-184 612.3 0.0 6.9e-184 611.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EON98642.1 - 5.5e-86 288.2 0.1 1.3e-85 286.9 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EON98642.1 - 3.4e-54 183.0 0.0 9.8e-53 178.2 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Glyco_hydro_7 PF00840.15 EON98643.1 - 1.5e-125 419.0 11.1 1.6e-125 418.8 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Lectin_C PF00059.16 EON98643.1 - 0.025 15.2 0.9 0.057 14.0 0.6 1.7 1 0 0 1 1 1 0 Lectin C-type domain Iso_dh PF00180.15 EON98644.1 - 3.7e-58 197.1 0.0 4.3e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.6 EON98644.1 - 0.034 14.4 0.2 14 6.0 0.0 2.4 2 0 0 2 2 2 0 Phenylalanine zipper RmlD_sub_bind PF04321.12 EON98645.1 - 1.2e-51 175.3 0.0 1.5e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EON98645.1 - 2.3e-24 86.1 0.0 7.9e-24 84.3 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON98645.1 - 5e-13 48.5 0.0 2e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EON98645.1 - 2.5e-10 39.5 0.0 1.3e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EON98645.1 - 3.2e-08 32.8 0.1 9.5e-05 21.4 0.0 3.0 1 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EON98645.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EON98645.1 - 0.0016 18.3 1.2 0.037 13.9 0.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EON98645.1 - 0.026 13.7 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.15 EON98645.1 - 0.041 13.8 0.1 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EON98645.1 - 0.5 9.9 2.0 5.5 6.6 0.1 2.2 1 1 1 2 2 2 0 KR domain Peptidase_M20 PF01546.23 EON98646.1 - 5.4e-26 91.2 0.0 7.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON98646.1 - 5.1e-18 64.8 0.0 9.5e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EON98646.1 - 2.6e-07 30.5 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EON98646.1 - 0.13 11.0 0.0 5 5.8 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Sec2p PF06428.6 EON98647.1 - 2.9e-09 36.6 12.7 1.9e-08 34.0 6.2 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 EON98647.1 - 0.0014 18.2 4.7 0.14 11.7 0.6 2.1 2 0 0 2 2 2 2 IncA protein Laminin_II PF06009.7 EON98647.1 - 0.018 14.7 8.7 0.1 12.3 1.9 2.2 2 0 0 2 2 2 0 Laminin Domain II Phage_lysis PF03245.8 EON98647.1 - 0.019 14.9 0.1 0.019 14.9 0.1 2.4 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein BLOC1_2 PF10046.4 EON98647.1 - 0.04 14.0 3.1 5.2 7.2 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_tail_1 PF01576.14 EON98647.1 - 0.059 11.0 21.2 0.046 11.4 8.8 2.0 2 0 0 2 2 2 0 Myosin tail ECSIT PF06239.6 EON98647.1 - 0.06 12.1 1.1 0.1 11.4 0.7 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Jnk-SapK_ap_N PF09744.4 EON98647.1 - 0.098 12.6 11.3 1 9.3 0.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF972 PF06156.8 EON98647.1 - 0.13 12.6 3.9 10 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EON98647.1 - 0.14 12.5 16.1 0.31 11.4 1.1 3.6 2 2 1 3 3 3 0 SlyX Tropomyosin PF00261.15 EON98647.1 - 0.16 10.9 18.0 0.81 8.7 0.6 2.1 2 0 0 2 2 2 0 Tropomyosin GAS PF13851.1 EON98647.1 - 0.65 9.1 8.8 2.3 7.3 4.1 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EON98647.1 - 0.83 8.5 9.8 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EON98647.1 - 0.91 8.1 7.5 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.11 EON98647.1 - 1.9 8.5 20.2 0.082 12.9 0.8 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein MbeD_MobD PF04899.7 EON98647.1 - 5.7 6.9 8.1 40 4.1 2.3 3.2 2 1 0 2 2 2 0 MbeD/MobD like Prefoldin PF02996.12 EON98647.1 - 6.8 6.3 8.7 16 5.1 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EON98647.1 - 7.5 6.3 12.8 2.8 7.6 0.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.27 EON98648.1 - 0.0033 16.5 0.3 0.9 9.0 0.0 4.4 6 0 0 6 6 6 1 EF hand EF-hand_6 PF13405.1 EON98648.1 - 0.0048 16.6 0.2 14 5.9 0.0 4.2 4 1 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 EON98648.1 - 0.0061 16.1 0.2 4.1 7.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EON98648.1 - 0.0099 15.9 0.0 6.1 7.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair TRI12 PF06609.8 EON98649.1 - 1.1e-57 195.5 23.3 1.3e-57 195.3 16.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON98649.1 - 9e-25 87.1 51.6 9.9e-25 86.9 32.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3087 PF11286.3 EON98649.1 - 0.43 9.8 2.5 0.72 9.0 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) TPR_1 PF00515.23 EON98650.1 - 1.1e-13 50.1 2.0 0.0039 16.7 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EON98650.1 - 3.1e-13 49.1 5.2 9.7e-08 31.5 0.2 4.3 3 2 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 EON98650.1 - 3.4e-11 42.0 6.2 0.0054 16.4 0.0 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EON98650.1 - 4.1e-10 40.0 10.2 1.6e-05 25.4 0.3 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON98650.1 - 2.3e-09 37.0 5.2 0.023 14.6 0.1 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EON98650.1 - 2.4e-09 36.3 11.9 1.2 9.1 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EON98650.1 - 1.3e-07 31.8 3.1 1.1 9.6 0.0 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EON98650.1 - 1.4e-07 31.5 9.9 0.17 12.5 0.0 5.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EON98650.1 - 9.6e-06 25.4 0.4 0.76 10.1 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EON98650.1 - 7.1e-05 22.8 0.1 0.0086 16.1 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EON98650.1 - 0.00059 19.6 2.4 0.18 11.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON98650.1 - 0.002 17.8 8.3 3.3 7.7 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON98650.1 - 0.0022 18.3 11.6 2.3 8.8 0.0 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 EON98650.1 - 0.0023 17.7 0.8 0.011 15.5 0.1 2.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) DUF4398 PF14346.1 EON98650.1 - 0.085 12.9 1.5 0.1 12.6 0.2 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4398) TPR_10 PF13374.1 EON98650.1 - 2.4 8.2 6.9 19 5.3 0.5 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 EON98652.1 - 6.2e-07 29.0 0.4 1.9e-06 27.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EON98652.1 - 0.0081 15.7 1.6 14 5.4 0.0 4.5 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EON98652.1 - 0.1 12.2 4.6 0.2 11.3 1.1 2.7 2 1 0 2 2 2 0 F-box domain PAF-AH_p_II PF03403.8 EON98653.1 - 1.5e-05 23.4 0.0 0.0056 15.0 0.0 2.3 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chorismate_bind PF00425.13 EON98654.1 - 0.092 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 chorismate binding enzyme Glycogen_syn PF05693.8 EON98655.1 - 0 1146.1 0.0 0 1145.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EON98655.1 - 6.6e-06 25.6 0.0 0.0091 15.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EON98655.1 - 1.8e-05 24.3 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EON98655.1 - 6.3e-05 23.1 0.0 0.00018 21.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain PI-PLC-X PF00388.14 EON98656.1 - 2.2e-59 199.0 0.0 4.2e-59 198.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EON98656.1 - 8.4e-39 132.2 0.0 2.7e-38 130.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EON98656.1 - 1.3e-07 31.3 0.1 3.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EON98656.1 - 7.4e-05 22.8 1.9 0.0062 16.6 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EON98656.1 - 0.01 15.6 0.3 0.3 11.0 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_like PF09279.6 EON98656.1 - 0.012 15.6 0.0 0.062 13.3 0.0 2.2 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 EON98656.1 - 0.039 13.2 0.0 0.21 10.9 0.0 2.3 1 0 0 1 1 1 0 EF hand EF-hand_10 PF14788.1 EON98656.1 - 0.047 13.3 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.17 EON98658.1 - 5.3e-16 58.0 0.0 3.3e-11 42.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98658.1 - 5.6e-12 45.4 0.0 6e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98658.1 - 5.7e-07 29.2 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EON98659.1 - 9.6e-70 234.6 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98659.1 - 1.4e-36 125.8 0.0 3.2e-36 124.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON98659.1 - 1.4e-06 27.4 0.1 3.1e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EON98659.1 - 0.0019 17.2 0.2 0.0037 16.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EON98659.1 - 0.037 13.7 0.6 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.3 EON98659.1 - 0.054 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 TP53IP5 PF15331.1 EON98659.1 - 0.37 10.6 4.3 0.61 9.9 3.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 XRN_N PF03159.13 EON98660.1 - 1.3e-102 342.2 0.0 2e-102 341.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Acetyltransf_6 PF13480.1 EON98660.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Proteasome PF00227.21 EON98661.1 - 3.7e-35 120.9 0.0 4.6e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SPX PF03105.14 EON98662.1 - 8.8e-42 143.7 5.1 8.8e-42 143.7 3.5 1.9 2 0 0 2 2 2 1 SPX domain EXS PF03124.9 EON98662.1 - 2.5e-15 56.3 13.7 9.8e-10 37.9 4.3 3.0 1 1 1 2 2 2 2 EXS family Cwf_Cwc_15 PF04889.7 EON98662.1 - 3 7.4 19.7 0.022 14.4 6.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.23 EON98664.1 - 2.5e-14 52.4 0.1 2.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme zf-RanBP PF00641.13 EON98665.1 - 2.1e-18 65.1 13.3 7.1e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EON98665.1 - 1e-08 34.7 0.0 2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EON98665.1 - 1.6e-07 31.7 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EON98665.1 - 9.2e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EON98665.1 - 3.2 7.6 10.7 0.77 9.6 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon UQ_con PF00179.21 EON98666.1 - 1.7e-22 79.3 0.0 2.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EON98666.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EON98666.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain PEP_mutase PF13714.1 EON98667.1 - 3.5e-38 131.1 0.3 4.8e-38 130.7 0.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1227 PF06777.6 EON98667.1 - 0.092 12.4 0.2 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) WD40 PF00400.27 EON98668.1 - 3.6e-49 162.9 24.8 5.9e-09 35.4 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EON98668.1 - 7e-43 146.1 0.4 9.6e-43 145.6 0.3 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EON98668.1 - 9.4e-07 28.7 0.1 0.0038 16.9 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EON98668.1 - 0.0008 18.2 0.0 0.47 9.1 0.0 3.2 2 2 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EON98668.1 - 0.0016 16.6 0.8 0.85 7.6 0.1 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 RRM_1 PF00076.17 EON98669.1 - 5.2e-08 32.4 0.0 9.5e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98669.1 - 7.7e-06 25.6 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98669.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EON98669.1 - 0.0034 17.0 0.9 0.006 16.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 EON98669.1 - 0.021 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF377 PF04041.8 EON98669.1 - 0.078 11.6 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF377) CAF1A PF12253.3 EON98670.1 - 9.7e-24 83.2 3.0 9.7e-24 83.2 2.1 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EON98670.1 - 0.00094 18.6 59.6 0.0022 17.3 41.3 1.7 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAPS PF04499.10 EON98670.1 - 1.3 7.5 9.6 2.1 6.8 6.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EON98670.1 - 3 5.4 15.4 4 5.0 10.6 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 EON98670.1 - 9.7 5.7 16.6 26 4.3 11.5 1.7 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EON98671.1 - 3.3e-50 170.7 39.6 3.9e-47 160.6 29.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EON98671.1 - 5.9e-21 74.3 24.3 9.8e-21 73.5 16.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EON98671.1 - 3.6e-17 62.0 29.0 1.3e-15 56.9 7.5 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Cut12 PF11500.3 EON98672.1 - 1.4e-45 154.6 13.9 1.4e-45 154.6 9.6 3.6 2 1 0 3 3 3 1 Spindle pole body formation-associated protein IncA PF04156.9 EON98672.1 - 0.48 10.0 46.8 0.56 9.7 14.2 2.9 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EON98672.1 - 1 8.4 10.4 0.84 8.7 3.6 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 EON98672.1 - 2.3 7.5 21.1 0.021 14.2 1.9 3.6 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) ERG2_Sigma1R PF04622.7 EON98673.1 - 1.1e-99 332.1 0.2 1.2e-99 331.9 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Fungal_trans_2 PF11951.3 EON98674.1 - 3.8e-05 22.4 2.5 0.0002 20.1 1.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain NPCC PF08058.6 EON98676.1 - 7e-11 42.1 0.0 8.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component WD40 PF00400.27 EON98677.1 - 4.8e-40 134.0 3.5 3.5e-09 36.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EON98677.1 - 7.3e-29 99.4 0.2 1.7e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3759 PF12585.3 EON98678.1 - 1.8e-36 123.8 5.9 2.2e-36 123.6 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Mor PF08765.6 EON98678.1 - 0.058 13.1 0.0 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 Mor transcription activator family AKAP_110 PF05716.8 EON98678.1 - 0.065 11.2 0.0 0.069 11.1 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Vps5 PF09325.5 EON98679.1 - 3.1e-74 249.1 9.2 3.1e-74 249.1 6.4 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EON98679.1 - 8.1e-25 86.8 0.3 1.8e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EON98679.1 - 0.0026 17.0 1.8 0.025 13.8 1.2 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_2 PF10455.4 EON98679.1 - 0.0049 15.8 7.1 0.0078 15.1 4.9 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking His_Phos_2 PF00328.17 EON98679.1 - 0.017 14.5 1.7 0.025 13.9 1.2 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 EON98679.1 - 0.038 13.5 6.5 0.076 12.5 4.5 1.5 1 1 0 1 1 1 0 BAR domain Atg14 PF10186.4 EON98679.1 - 0.64 8.9 4.3 1 8.2 3.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ebp2 PF05890.7 EON98680.1 - 2.5e-90 302.4 18.8 2.5e-90 302.4 13.0 3.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 EXOSC1 PF10447.4 EON98682.1 - 7.5e-29 99.5 1.0 1.1e-28 99.0 0.7 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EON98682.1 - 3.6e-14 51.7 0.0 8e-14 50.6 0.0 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EON98682.1 - 0.0033 17.4 0.1 0.03 14.3 0.1 2.2 1 1 0 1 1 1 1 S1 RNA binding domain Acyl-CoA_dh_1 PF00441.19 EON98683.1 - 4.4e-28 98.2 0.9 6.7e-28 97.6 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EON98683.1 - 2e-15 56.0 0.0 4.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EON98683.1 - 9.7e-13 48.5 0.3 1.6e-12 47.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EON98683.1 - 5.1e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Glyco_hydro_31 PF01055.21 EON98684.1 - 1.6e-156 521.6 3.3 2e-156 521.2 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EON98684.1 - 2.1e-21 75.5 0.2 8.8e-21 73.5 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 EON98685.1 - 4.4e-55 185.1 0.0 5e-55 184.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NmrA PF05368.8 EON98686.1 - 2.2e-79 266.0 0.0 2.7e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98686.1 - 4.7e-05 23.4 0.3 0.2 11.6 0.5 2.3 1 1 1 2 2 2 2 NADH(P)-binding F420_oxidored PF03807.12 EON98686.1 - 0.11 12.9 0.1 2.3 8.7 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PSGP PF07276.6 EON98687.1 - 0.28 11.4 2.4 0.63 10.3 1.7 1.6 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) p450 PF00067.17 EON98688.1 - 2.5e-31 108.6 0.0 1.6e-25 89.5 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 Spo12 PF05032.7 EON98689.1 - 1.2e-15 56.8 0.2 2.6e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 Spo12 family Flavin_Reduct PF01613.13 EON98690.1 - 4.9e-33 114.1 0.0 5.6e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain MS_channel PF00924.13 EON98691.1 - 5.5e-22 78.1 0.7 1e-21 77.2 0.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 EON98691.1 - 0.0026 17.8 0.1 0.0066 16.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF2985 PF11204.3 EON98691.1 - 0.064 13.0 2.0 0.34 10.7 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2985) EF-hand_6 PF13405.1 EON98691.1 - 0.072 13.0 0.3 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EON98691.1 - 0.11 11.8 0.9 0.64 9.4 0.4 2.3 2 0 0 2 2 2 0 EF hand DUF4349 PF14257.1 EON98691.1 - 0.11 11.6 0.9 2.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) ELO PF01151.13 EON98692.1 - 1.3e-63 214.6 17.3 1.5e-63 214.4 12.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEAD PF00270.24 EON98693.1 - 3.7e-47 159.9 0.0 8.6e-46 155.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON98693.1 - 3.2e-28 97.3 0.1 7e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON98693.1 - 0.0048 16.7 0.0 0.0099 15.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EON98693.1 - 0.036 13.1 0.1 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EON98693.1 - 0.093 11.1 0.0 0.19 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) MCM PF00493.18 EON98694.1 - 1.7e-141 470.8 0.1 2.3e-141 470.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EON98694.1 - 9.6e-19 68.0 1.6 1.8e-18 67.2 0.4 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EON98694.1 - 6.7e-07 28.6 0.0 0.00021 20.4 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EON98694.1 - 1.9e-05 24.4 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EON98694.1 - 0.00031 20.3 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EON98694.1 - 0.029 14.7 0.3 0.1 13.0 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EON98694.1 - 0.044 13.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EON98694.1 - 0.096 12.8 0.5 0.35 11.0 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.19 EON98695.1 - 9.7e-88 294.7 26.6 1.1e-87 294.5 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98695.1 - 2.6e-28 98.7 24.4 4.3e-28 98.0 14.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON98695.1 - 8.7e-06 24.2 2.7 8.7e-06 24.2 1.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ost4 PF10215.4 EON98695.1 - 0.019 14.4 2.6 0.14 11.6 0.1 3.0 2 0 0 2 2 2 0 Oligosaccaryltransferase Laminin_I PF06008.9 EON98696.1 - 3.6e-05 23.2 23.1 0.0011 18.3 8.2 2.2 2 0 0 2 2 2 2 Laminin Domain I IncA PF04156.9 EON98696.1 - 0.00034 20.2 31.3 0.0011 18.6 3.7 2.4 1 1 1 2 2 2 2 IncA protein CENP-F_leu_zip PF10473.4 EON98696.1 - 0.0013 18.5 17.9 0.0013 18.5 12.4 3.6 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EON98696.1 - 0.0022 17.8 9.3 0.0042 16.9 0.1 3.1 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EON98696.1 - 0.0025 17.3 26.8 0.1 12.1 6.4 3.3 1 1 2 3 3 3 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EON98696.1 - 0.0045 16.2 7.5 0.24 10.5 4.2 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EON98696.1 - 0.0045 14.7 33.6 0.035 11.8 19.1 2.2 1 1 1 2 2 2 2 Myosin tail DUF4201 PF13870.1 EON98696.1 - 0.0046 16.4 7.5 0.0046 16.4 5.2 3.3 1 1 0 3 3 3 1 Domain of unknown function (DUF4201) Filament PF00038.16 EON98696.1 - 0.0051 16.3 28.0 0.078 12.4 6.9 2.8 1 1 1 2 2 2 2 Intermediate filament protein AAA_13 PF13166.1 EON98696.1 - 0.0076 14.7 21.7 0.064 11.7 15.1 2.0 1 1 0 1 1 1 1 AAA domain DUF3508 PF12018.3 EON98696.1 - 0.032 13.2 9.6 0.055 12.4 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF972 PF06156.8 EON98696.1 - 0.16 12.3 22.5 0.032 14.5 3.2 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EON98696.1 - 0.18 11.6 33.9 0.85 9.4 10.1 3.3 1 1 2 3 3 3 0 Tropomyosin like NPV_P10 PF05531.7 EON98696.1 - 0.88 9.8 12.3 26 5.1 0.5 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 EON98696.1 - 1 8.8 32.5 0.83 9.1 5.0 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.6 EON98696.1 - 1.2 8.8 31.3 1.9 8.2 1.1 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 EON98696.1 - 1.4 8.7 14.3 2.4 7.9 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EON98696.1 - 2.1 8.1 32.0 0.1 12.3 10.0 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EON98696.1 - 2.7 7.8 27.6 3 7.7 2.9 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.13 EON98696.1 - 3.1 8.2 15.1 1.1 9.7 2.7 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.6 EON98696.1 - 3.5 6.2 26.3 6.4 5.3 5.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.6 EON98696.1 - 4.1 7.3 17.7 2.1 8.2 0.1 4.9 4 2 2 6 6 5 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EON98696.1 - 4.2 7.1 10.3 5.1 6.9 1.5 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 EON98696.1 - 5 6.6 30.8 1.1 8.8 2.7 4.8 3 1 2 5 5 5 0 Septum formation initiator BLOC1_2 PF10046.4 EON98696.1 - 5.9 7.1 17.5 2.6 8.2 3.7 3.6 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EON98696.1 - 6.3 5.7 28.2 4.5 6.2 2.4 2.4 1 1 3 4 4 4 0 Autophagy protein Apg6 Uds1 PF15456.1 EON98696.1 - 7.2 6.6 25.2 0.67 9.9 3.7 2.9 1 1 0 2 2 2 0 Up-regulated During Septation V_ATPase_I PF01496.14 EON98696.1 - 7.8 4.2 19.5 2.6 5.7 3.1 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EON98696.1 - 8.3 6.1 34.2 2.9 7.6 7.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EON98696.1 - 9.9 6.0 33.9 4.3 7.2 3.5 4.9 2 2 3 5 5 5 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.27 EON98697.1 - 7.2e-29 98.6 9.7 2.4e-07 30.3 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EON98697.1 - 0.14 11.9 0.2 20 4.9 0.0 3.2 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region SecY PF00344.15 EON98698.1 - 5.3e-96 321.5 9.9 6.7e-96 321.2 6.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EON98698.1 - 1.3e-18 66.1 0.2 7.2e-18 63.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p Hid1 PF12722.2 EON98699.1 - 1.3e-159 532.7 0.7 5.2e-88 295.7 0.0 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EON98699.1 - 9.8e-53 179.2 0.2 3.3e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein zf-C2H2 PF00096.21 EON98700.1 - 2.2e-08 33.9 13.6 0.031 14.6 0.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EON98700.1 - 0.00034 20.4 0.4 0.00034 20.4 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EON98700.1 - 0.0098 16.0 11.3 0.14 12.3 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EON98700.1 - 0.016 15.1 7.5 0.96 9.4 0.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 EON98700.1 - 0.019 15.2 0.9 0.019 15.2 0.6 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.6 EON98700.1 - 0.69 9.6 3.1 18 5.0 0.3 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-IS66 PF13005.2 EON98700.1 - 1.3 9.0 8.8 3.9 7.5 0.3 2.9 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 CpXC PF14353.1 EON98700.1 - 1.4 8.8 10.2 0.85 9.5 0.3 3.4 2 2 0 3 3 3 0 CpXC protein zf-C2H2_2 PF12756.2 EON98700.1 - 4.6 7.4 12.5 1.4 9.0 0.3 3.8 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EON98700.1 - 5.8 7.3 22.1 1.4 9.3 1.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain COX5A PF02284.11 EON98701.1 - 2.1e-39 133.8 0.2 2.9e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va UQ_con PF00179.21 EON98702.1 - 3.9e-38 130.0 0.0 5.1e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EON98702.1 - 6.9e-06 25.5 0.1 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EON98702.1 - 0.0037 17.0 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EON98702.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Aldo_ket_red PF00248.16 EON98703.1 - 1.5e-63 214.2 0.0 1.9e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LysM PF01476.15 EON98703.1 - 1.8e-13 50.1 0.0 8.7e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 LysM domain Phage_tail_X PF05489.7 EON98703.1 - 0.055 12.9 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Phage Tail Protein X Fungal_trans PF04082.13 EON98704.1 - 6.9e-16 57.9 0.9 1.9e-15 56.4 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.1 EON98705.1 - 4.2e-13 48.7 0.4 3.7e-09 36.1 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EON98705.1 - 1.2e-08 34.1 5.1 0.0014 18.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EON98705.1 - 1.2e-05 24.6 1.6 0.37 10.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON98705.1 - 6.2e-05 22.8 0.5 0.023 14.6 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON98705.1 - 0.00015 22.2 3.0 0.023 15.3 0.3 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EON98705.1 - 0.00085 18.9 0.3 0.63 9.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EON98705.1 - 0.013 15.7 0.1 0.31 11.4 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EON98705.1 - 0.088 13.4 2.7 1.7 9.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EON98705.1 - 0.37 10.6 1.9 22 4.9 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Methyltransf_25 PF13649.1 EON98706.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON98706.1 - 6.9e-11 42.5 0.0 2.2e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98706.1 - 4.2e-10 39.5 0.0 3.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98706.1 - 1.1e-09 38.7 0.0 2.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON98706.1 - 1e-07 32.0 0.0 3.6e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98706.1 - 2.1e-07 31.3 0.0 6.8e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98706.1 - 2.6e-06 27.0 0.0 0.09 12.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain CheR PF01739.13 EON98706.1 - 0.0009 18.5 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EON98706.1 - 0.01 14.9 0.0 0.026 13.6 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EON98706.1 - 0.033 13.8 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EON98706.1 - 0.058 14.2 0.0 0.14 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EON98706.1 - 0.34 10.2 1.2 0.74 9.1 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase small domain OPT PF03169.10 EON98707.1 - 1.1e-87 294.9 41.6 1.4e-87 294.6 28.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribonuclease_T2 PF00445.13 EON98708.1 - 7.2e-22 77.9 0.0 8.7e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family SNF2_N PF00176.18 EON98709.1 - 1.4e-71 240.7 0.7 2.7e-71 239.8 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EON98709.1 - 1.6e-50 170.7 17.2 1.6e-50 170.7 11.9 4.5 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EON98709.1 - 4.1e-16 58.5 0.0 9.1e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chalcone PF02431.10 EON98710.1 - 5.2e-64 215.3 0.0 6.8e-64 214.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase UCR_Fe-S_N PF10399.4 EON98710.1 - 0.029 13.5 0.8 0.067 12.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 EON98710.1 - 0.93 9.6 5.6 0.13 12.3 0.4 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RAI16-like PF10257.4 EON98712.1 - 1.1e-61 208.7 0.3 2.5e-61 207.5 0.2 1.5 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein Clr5 PF14420.1 EON98713.1 - 1.8e-06 27.7 0.5 3e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 Clr5 domain HD PF01966.17 EON98714.1 - 2.6e-05 24.2 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 HD domain Inhibitor_I68 PF10468.4 EON98715.1 - 0.18 12.0 0.1 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 GAS PF13851.1 EON98715.1 - 0.29 10.3 28.7 2.7 7.1 13.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding 4HBT_2 PF13279.1 EON98717.1 - 7.5e-20 71.5 0.2 9.3e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily eIF3_N PF09440.5 EON98717.1 - 0.086 13.0 0.5 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Lipase_3 PF01764.20 EON98718.1 - 7e-19 67.8 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EON98718.1 - 0.0052 16.1 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hox9_act PF04617.8 EON98718.1 - 0.0065 16.6 0.2 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Hox9 activation region X PF00739.14 EON98718.1 - 0.026 14.4 1.8 0.031 14.1 0.3 1.9 2 0 0 2 2 2 0 Trans-activation protein X Abhydrolase_6 PF12697.2 EON98718.1 - 0.043 13.6 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy_4 PF13661.1 EON98718.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RunxI PF08504.6 EON98718.1 - 2.4 8.6 6.7 1.5 9.2 3.1 1.8 2 0 0 2 2 2 0 Runx inhibition domain FAD_binding_4 PF01565.18 EON98719.1 - 4.2e-22 78.1 3.9 4.2e-22 78.1 2.7 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EON98719.1 - 1e-12 47.7 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2701 PF10857.3 EON98719.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) TRI12 PF06609.8 EON98720.1 - 7.8e-62 209.3 23.7 1e-61 208.9 16.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON98720.1 - 7.4e-25 87.3 41.6 1.9e-23 82.7 25.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98720.1 - 6.6e-12 44.7 13.0 6.6e-12 44.7 9.0 3.4 2 1 1 4 4 4 1 Sugar (and other) transporter DUF1049 PF06305.6 EON98720.1 - 0.038 13.4 8.0 0.32 10.5 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Ank_2 PF12796.2 EON98721.1 - 1.3e-43 147.1 1.6 3.3e-14 52.9 0.0 3.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EON98721.1 - 8.8e-25 85.2 0.0 4.1e-06 26.3 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EON98721.1 - 8.8e-23 80.2 0.0 5.5e-09 36.3 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON98721.1 - 1.6e-16 59.9 0.1 9.9e-05 22.4 0.0 5.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON98721.1 - 7.3e-14 50.5 0.1 0.00093 19.2 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat TPR_12 PF13424.1 EON98721.1 - 8e-05 22.5 0.6 0.00066 19.5 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EON98721.1 - 0.0012 18.6 2.3 0.0031 17.3 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EON98721.1 - 0.013 15.1 1.0 0.033 13.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EON98721.1 - 0.022 14.7 0.1 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EON98721.1 - 0.073 12.7 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 EON98721.1 - 0.11 12.3 0.0 0.57 10.0 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EON98721.1 - 0.11 13.1 0.4 0.35 11.5 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MPC PF03650.8 EON98722.1 - 8.2e-33 112.8 0.1 9.3e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Sod_Fe_C PF02777.13 EON98723.1 - 2e-34 117.5 0.3 3e-34 117.0 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EON98723.1 - 2e-19 69.6 5.0 2.9e-19 69.0 1.8 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Zn_clus PF00172.13 EON98724.1 - 0.056 13.3 6.9 0.11 12.3 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Prismane PF03063.15 EON98724.1 - 0.098 11.0 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DHODB_Fe-S_bind PF10418.4 EON98724.1 - 1.9 8.0 4.7 7.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF89 PF01937.14 EON98725.1 - 5.2e-107 357.7 0.1 4.1e-106 354.7 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF89 BAG PF02179.11 EON98726.1 - 4.9e-18 65.0 0.4 1.1e-17 63.9 0.3 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EON98726.1 - 9e-05 21.8 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EON98726.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Acyltransferase PF01553.16 EON98727.1 - 1.2e-25 89.4 0.0 2.7e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase NAD_kinase PF01513.16 EON98728.1 - 3.8e-49 166.9 0.0 1.6e-48 164.9 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase YbjM PF11045.3 EON98728.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Radical_SAM PF04055.16 EON98730.1 - 2e-15 57.3 0.0 5.8e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EON98730.1 - 2.5e-12 46.6 0.0 6.3e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ytp1 PF10355.4 EON98731.1 - 7.8e-86 287.6 15.3 7.8e-86 287.6 10.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EON98731.1 - 4.8e-23 80.7 2.9 4.8e-23 80.7 2.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4225 PF13988.1 EON98731.1 - 0.45 9.9 3.0 0.17 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) DUF897 PF05982.7 EON98731.1 - 0.59 8.8 9.7 0.03 13.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF897) DUF959 PF06121.9 EON98732.1 - 0.18 11.4 0.2 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) CoA_binding PF02629.14 EON98733.1 - 2.5e-25 88.7 4.3 9.4e-25 86.9 0.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EON98733.1 - 9.4e-24 83.7 0.3 1.4e-23 83.1 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EON98733.1 - 2.8e-09 36.6 0.0 4.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EON98733.1 - 0.0017 18.5 0.0 0.0044 17.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain DUF500 PF04366.7 EON98734.1 - 4.7e-40 135.9 0.0 7.3e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) 3Beta_HSD PF01073.14 EON98735.1 - 5.4e-49 166.3 0.0 6.6e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EON98735.1 - 2.9e-32 111.9 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EON98735.1 - 8.1e-16 57.6 0.0 6.3e-12 44.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EON98735.1 - 1e-12 47.5 0.1 1.6e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EON98735.1 - 3e-12 46.9 0.1 4.6e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EON98735.1 - 4.1e-12 46.3 0.3 1.6e-11 44.4 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON98735.1 - 5.6e-10 39.1 0.2 2.5e-09 37.0 0.1 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EON98735.1 - 4.5e-07 29.0 0.4 2.8e-06 26.4 0.3 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EON98735.1 - 0.00027 20.2 0.2 0.00044 19.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 EON98735.1 - 0.015 15.6 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain LysR_substrate PF03466.15 EON98735.1 - 0.06 12.4 0.2 8 5.5 0.0 2.3 2 0 0 2 2 2 0 LysR substrate binding domain HemS PF05171.7 EON98735.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain FtsJ PF01728.14 EON98735.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glyco_hydro_72 PF03198.9 EON98736.1 - 1.7e-124 414.9 3.1 2.2e-124 414.5 2.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EON98736.1 - 1.9e-21 76.3 3.8 6.4e-21 74.6 2.6 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EON98736.1 - 6.8e-07 28.4 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CFC PF09443.5 EON98736.1 - 0.058 13.0 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Lactonase PF10282.4 EON98737.1 - 2.8e-65 220.6 0.0 3.3e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LVIVD PF08309.6 EON98737.1 - 0.048 12.6 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 LVIVD repeat Glutaredoxin PF00462.19 EON98738.1 - 1.3e-21 76.3 0.0 1.8e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EON98738.1 - 0.0022 18.1 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 EON98738.1 - 0.0097 15.4 0.1 0.34 10.4 0.1 2.1 1 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 EON98738.1 - 0.018 14.5 0.1 0.028 13.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 EON98738.1 - 0.027 14.6 0.3 0.095 12.9 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 EON98738.1 - 0.028 14.6 0.1 0.045 14.0 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.1 EON98738.1 - 0.082 12.3 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 EON98738.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EON98738.1 - 0.12 12.1 0.1 0.37 10.6 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EON98738.1 - 0.13 12.3 1.4 10 6.0 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Cerato-platanin PF07249.7 EON98739.1 - 1.1e-51 173.8 0.7 1.3e-51 173.6 0.5 1.0 1 0 0 1 1 1 1 Cerato-platanin NAD_binding_8 PF13450.1 EON98740.1 - 2e-10 40.5 0.1 3.7e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EON98740.1 - 8.2e-05 21.8 0.0 0.005 15.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EON98740.1 - 0.0001 21.3 0.0 0.00018 20.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON98740.1 - 0.00052 18.6 1.2 0.00079 17.9 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EON98740.1 - 0.0011 19.0 0.1 0.022 14.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON98740.1 - 0.0041 17.4 2.4 0.022 15.1 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON98740.1 - 0.0044 15.9 2.7 0.0065 15.3 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EON98740.1 - 0.0062 15.5 0.5 0.024 13.5 0.6 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EON98740.1 - 0.01 14.9 0.2 0.025 13.6 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON98740.1 - 0.013 15.4 0.1 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EON98740.1 - 0.066 12.6 0.9 0.13 11.7 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EON98740.1 - 0.084 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EON98740.1 - 0.21 10.5 1.1 0.33 9.9 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.13 EON98742.1 - 5.1e-30 104.2 35.1 8.4e-30 103.5 24.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Exo_endo_phos PF03372.18 EON98743.1 - 3.9e-22 79.4 0.1 4.8e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EON98743.1 - 1.3e-05 24.7 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF2305 PF10230.4 EON98744.1 - 2.1e-58 197.8 0.0 2.4e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EON98744.1 - 0.0011 18.9 1.2 0.0016 18.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON98744.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AA_permease_2 PF13520.1 EON98745.1 - 1.3e-49 168.8 44.2 1.7e-49 168.5 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON98745.1 - 1.6e-17 63.0 41.1 2.2e-17 62.5 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4407 PF14362.1 EON98746.1 - 0.36 9.7 10.6 0.4 9.6 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1151 PF06625.6 EON98746.1 - 1.4 8.6 11.6 0.08 12.6 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) NAM-associated PF14303.1 EON98746.1 - 3.9 7.7 13.7 4.8 7.4 9.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ribosomal_L13 PF00572.13 EON98747.1 - 1.7e-28 99.2 0.3 3.1e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 EON98747.1 - 0.026 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain GFO_IDH_MocA PF01408.17 EON98748.1 - 1.7e-22 80.1 0.1 4.4e-22 78.8 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EON98748.1 - 2.9e-13 49.6 0.0 5.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EON98748.1 - 1.6e-05 25.2 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EON98748.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA_33 PF13671.1 EON98748.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EON98749.1 - 3.1e-41 140.6 0.0 6e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EON98749.1 - 5.2e-07 29.8 0.1 0.00019 21.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EON98749.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EON98749.1 - 1e-05 24.6 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EON98749.1 - 4.3e-05 23.2 0.1 0.00015 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EON98749.1 - 0.00021 21.3 0.1 0.00093 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EON98749.1 - 0.00028 19.9 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EON98749.1 - 0.0012 18.8 0.8 0.004 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EON98749.1 - 0.0021 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EON98749.1 - 0.0026 17.4 0.2 0.35 10.5 0.1 2.8 2 1 1 3 3 3 1 NACHT domain AAA_17 PF13207.1 EON98749.1 - 0.0039 18.0 0.2 0.011 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EON98749.1 - 0.0061 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EON98749.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EON98749.1 - 0.0076 16.1 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EON98749.1 - 0.0092 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EON98749.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EON98749.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EON98749.1 - 0.015 14.5 2.0 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 EON98749.1 - 0.021 13.5 0.7 0.045 12.4 0.1 1.8 2 1 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 EON98749.1 - 0.03 13.4 0.2 0.42 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 EON98749.1 - 0.04 12.7 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EON98749.1 - 0.043 13.9 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EON98749.1 - 0.049 13.2 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EON98749.1 - 0.054 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EON98749.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EON98749.1 - 0.37 10.1 6.1 0.27 10.6 0.3 2.7 2 1 0 3 3 3 0 AAA domain DUF4131 PF13567.1 EON98753.1 - 0.48 9.8 5.0 0.76 9.1 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3317 PF11779.3 EON98753.1 - 1.3 8.4 5.4 2.8 7.4 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) CFEM PF05730.6 EON98754.1 - 1.9e-11 43.5 18.6 1.9e-11 43.5 12.9 2.0 2 1 0 2 2 2 1 CFEM domain Gamma-thionin PF00304.15 EON98754.1 - 0.19 11.7 4.1 0.4 10.7 2.9 1.5 1 0 0 1 1 1 0 Gamma-thionin family ABC_tran PF00005.22 EON98755.1 - 2.7e-45 154.0 0.0 2.2e-21 76.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EON98755.1 - 4.2e-20 71.3 3.2 4.2e-20 71.3 2.2 2.7 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 EON98755.1 - 8.9e-20 71.8 0.4 0.00015 21.8 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EON98755.1 - 2.7e-12 46.3 0.1 0.00034 19.9 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EON98755.1 - 5.3e-09 35.4 0.2 0.00094 18.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EON98755.1 - 5.7e-09 36.5 4.3 0.062 13.6 0.0 3.7 4 0 0 4 4 3 3 AAA domain AAA_17 PF13207.1 EON98755.1 - 4.9e-07 30.5 0.1 0.0096 16.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EON98755.1 - 2.2e-06 26.9 0.0 0.004 16.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EON98755.1 - 3.8e-06 27.2 0.2 0.04 14.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EON98755.1 - 4.7e-06 26.7 0.0 0.17 11.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EON98755.1 - 2.8e-05 24.0 0.0 0.057 13.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EON98755.1 - 3.5e-05 23.8 0.5 0.16 11.9 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EON98755.1 - 8.5e-05 22.4 0.0 0.09 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EON98755.1 - 9.6e-05 22.3 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EON98755.1 - 0.00012 22.1 1.0 0.9 9.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.24 EON98755.1 - 0.00015 21.9 0.0 0.95 9.6 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EON98755.1 - 0.00016 21.3 0.1 0.79 9.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.9 EON98755.1 - 0.00031 20.5 0.1 0.75 9.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Miro PF08477.8 EON98755.1 - 0.00035 21.0 0.0 0.94 9.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EON98755.1 - 0.00069 18.7 0.0 0.13 11.2 0.0 2.9 4 0 0 4 4 3 1 AAA ATPase domain AAA_10 PF12846.2 EON98755.1 - 0.0013 18.2 0.8 0.96 8.8 0.1 2.7 3 0 0 3 3 2 2 AAA-like domain NB-ARC PF00931.17 EON98755.1 - 0.0017 17.2 0.3 0.22 10.3 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 EON98755.1 - 0.0025 17.5 0.1 1.4 8.5 0.0 2.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EON98755.1 - 0.0033 17.3 0.0 2.1 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EON98755.1 - 0.0036 16.7 0.0 0.62 9.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EON98755.1 - 0.0065 16.3 0.4 0.72 9.8 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EON98755.1 - 0.01 15.5 0.3 0.28 10.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2813 PF11398.3 EON98755.1 - 0.03 13.3 0.1 8.1 5.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.4 EON98755.1 - 0.041 13.3 0.8 2.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EON98755.1 - 0.044 13.5 0.1 7.1 6.4 0.0 3.3 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.12 EON98755.1 - 0.047 13.5 0.3 11 5.7 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 DAP3 PF10236.4 EON98755.1 - 0.052 12.4 0.6 9.1 5.1 0.0 2.8 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 EON98755.1 - 0.057 13.1 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 EON98755.1 - 0.07 12.0 0.1 2.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EON98755.1 - 0.079 12.4 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 EON98755.1 - 0.23 10.2 1.3 16 4.1 0.0 3.2 4 0 0 4 4 4 0 ArgK protein Sulfotransfer_3 PF13469.1 EON98756.1 - 2.7e-05 25.1 0.0 3.9e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family p450 PF00067.17 EON98757.1 - 1.3e-06 27.2 0.0 1.5e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dabb PF07876.7 EON98758.1 - 1.2e-08 35.2 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SAICAR_synt PF01259.13 EON98759.1 - 9.8e-88 293.4 0.0 1.2e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Phage_XkdX PF09693.5 EON98759.1 - 0.022 14.3 0.4 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) YIF1 PF03878.10 EON98760.1 - 1.7e-74 250.0 5.5 2e-74 249.7 3.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EON98760.1 - 6.7e-05 22.4 8.8 6.7e-05 22.4 6.1 1.6 2 0 0 2 2 2 1 Yip1 domain Baculo_LEF-11 PF06385.7 EON98760.1 - 0.12 12.4 0.2 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DUF983 PF06170.7 EON98760.1 - 0.68 10.0 3.9 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) p450 PF00067.17 EON98761.1 - 2e-43 148.5 0.0 2.7e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrolase_6 PF13344.1 EON98762.1 - 4.3e-23 81.1 0.0 9.2e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EON98762.1 - 1.7e-14 53.2 0.0 1.1e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EON98762.1 - 0.00076 19.7 0.0 0.036 14.2 0.0 2.8 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON98762.1 - 0.01 16.2 0.0 18 5.6 0.0 3.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EON98763.1 - 3.4e-14 52.3 20.2 3.4e-14 52.3 14.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98763.1 - 6.2e-05 21.7 12.2 9.9e-05 21.0 8.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98764.1 - 6.3e-38 130.3 43.4 4.1e-36 124.4 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98764.1 - 7.9e-05 21.4 12.9 9.6e-05 21.1 8.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EON98764.1 - 0.016 14.9 0.8 1.5 8.7 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family MoaE PF02391.12 EON98765.1 - 8.2e-33 112.6 0.0 1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein DUF4646 PF15496.1 EON98765.1 - 0.11 12.5 0.4 4.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4646) Pkinase PF00069.20 EON98766.1 - 1.6e-58 197.9 0.0 7.1e-58 195.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98766.1 - 2e-28 99.2 0.4 7.9e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EON98766.1 - 3.4e-08 33.8 0.7 9e-08 32.5 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EON98766.1 - 0.00048 19.1 0.3 0.0029 16.5 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EON98766.1 - 0.004 16.9 0.1 0.087 12.5 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EON98766.1 - 0.078 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3502 PF12010.3 EON98766.1 - 0.12 12.3 0.3 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) tRNA-synt_1b PF00579.20 EON98767.1 - 1.7e-45 155.4 0.0 2.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HATPase_c PF02518.21 EON98769.1 - 1.9e-22 79.0 0.0 4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EON98769.1 - 1.4e-20 73.3 1.0 6e-19 68.1 0.1 2.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EON98769.1 - 2.1e-13 50.5 0.0 5.1e-07 30.0 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EON98769.1 - 2.9e-08 33.7 0.0 0.0054 16.7 0.0 3.4 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EON98769.1 - 2e-07 30.6 0.0 0.0037 17.0 0.0 3.0 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 EON98769.1 - 2.2e-07 30.7 1.1 9.1e-07 28.7 0.1 2.7 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EON98769.1 - 3.6e-06 26.7 0.0 0.026 14.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EON98769.1 - 9.1e-06 25.6 0.0 0.025 14.5 0.0 4.3 4 0 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.1 EON98769.1 - 0.023 14.3 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Choline_kinase PF01633.15 EON98770.1 - 1.1e-63 214.6 0.0 1.6e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EON98770.1 - 7.4e-20 70.1 0.0 1.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EON98770.1 - 3e-07 30.4 0.8 6.5e-07 29.3 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DFP PF04127.10 EON98772.1 - 4.4e-14 52.5 0.0 6.9e-06 25.7 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein SCO1-SenC PF02630.9 EON98773.1 - 8.9e-59 198.0 0.0 1.2e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EON98773.1 - 0.00024 20.8 0.0 0.00046 19.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EON98773.1 - 0.00062 19.8 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EON98773.1 - 0.042 13.3 0.0 0.53 9.8 0.0 2.1 1 1 0 1 1 1 0 Redoxin PHD PF00628.24 EON98774.1 - 7.9e-12 44.6 6.6 1.7e-11 43.6 4.6 1.6 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 EON98774.1 - 0.039 12.6 2.3 0.082 11.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) BTB PF00651.26 EON98775.1 - 3e-12 46.5 0.7 3.3e-11 43.1 0.4 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pyr_redox_3 PF13738.1 EON98776.1 - 1.5e-21 77.3 0.0 2.3e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EON98776.1 - 2.9e-17 62.0 0.1 3e-14 52.1 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EON98776.1 - 6.7e-10 39.1 0.0 1.8e-09 37.7 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON98776.1 - 2.3e-09 36.6 0.0 1.1e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EON98776.1 - 7.5e-09 35.4 0.0 1.1e-06 28.4 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EON98776.1 - 1.7e-05 23.9 0.9 0.023 13.5 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON98776.1 - 0.00069 19.9 0.3 2.9 8.3 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EON98776.1 - 0.0018 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EON98776.1 - 0.0026 16.9 0.2 0.0063 15.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EON98776.1 - 0.016 15.0 5.3 7.5 6.3 0.0 4.6 4 1 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EON98776.1 - 0.038 12.4 0.7 0.18 10.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 EON98776.1 - 0.054 13.5 0.0 20 5.2 0.0 3.4 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EON98776.1 - 0.16 10.8 1.6 0.14 11.0 0.1 1.7 2 1 0 2 2 2 0 Lycopene cyclase protein Lipase_GDSL_2 PF13472.1 EON98777.1 - 4.3e-08 33.5 0.9 1.1e-07 32.1 0.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EON98777.1 - 7.8e-07 29.1 8.8 4.5e-06 26.6 6.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.16 EON98778.1 - 1.7e-67 228.2 3.7 2.2e-67 227.8 2.5 1.2 1 0 0 1 1 1 1 Amidase RNA_GG_bind PF10258.4 EON98778.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain DUF1752 PF08550.5 EON98779.1 - 4.5e-13 48.5 2.2 7.8e-13 47.7 1.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Polyketide_cyc2 PF10604.4 EON98780.1 - 0.00052 20.2 0.7 0.0016 18.6 0.5 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pkinase PF00069.20 EON98782.1 - 9e-56 188.8 0.0 1.4e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON98782.1 - 2.9e-35 121.5 0.0 2.9e-34 118.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON98782.1 - 0.00074 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 EON98782.1 - 0.0016 17.3 0.1 0.0057 15.5 0.0 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 APH PF01636.18 EON98782.1 - 0.041 13.6 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Filament PF00038.16 EON98782.1 - 1.3 8.3 14.9 0.28 10.6 7.9 1.5 2 0 0 2 2 2 0 Intermediate filament protein ketoacyl-synt PF00109.21 EON98783.1 - 1.2e-76 257.5 0.1 1.9e-76 256.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EON98783.1 - 7.1e-58 195.2 0.1 1.4e-57 194.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EON98783.1 - 7.7e-58 196.3 0.2 9.4e-57 192.7 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 EON98783.1 - 3.1e-42 144.3 0.1 7.6e-42 143.0 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EON98783.1 - 1.4e-41 142.6 0.0 2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EON98783.1 - 5.6e-36 122.9 0.0 1.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EON98783.1 - 1.1e-09 37.9 0.1 6.2e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EON98783.1 - 0.00049 20.3 0.1 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EON98783.1 - 0.0033 16.4 0.1 0.0069 15.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.1 EON98783.1 - 0.033 13.9 0.1 1 9.0 0.0 2.4 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ThiF PF00899.16 EON98783.1 - 0.06 13.1 0.8 0.15 11.8 0.5 1.7 1 0 0 1 1 1 0 ThiF family Asp PF00026.18 EON98784.1 - 4.1e-62 210.2 3.3 7.3e-62 209.4 2.3 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON98784.1 - 6.5e-09 35.9 2.1 1.3e-08 35.0 0.0 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EON98784.1 - 0.00015 22.1 3.4 0.069 13.6 1.1 3.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EON98784.1 - 0.016 14.9 2.9 0.83 9.5 0.4 3.1 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease OPT PF03169.10 EON98785.1 - 1.8e-169 565.1 50.4 2.1e-169 564.9 35.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein G-patch PF01585.18 EON98786.1 - 5.9e-10 38.7 2.7 1.2e-09 37.7 0.3 2.5 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 EON98786.1 - 2.7e-05 23.9 0.5 9.7e-05 22.1 0.3 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 EON98786.1 - 0.0004 19.9 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EON98786.1 - 0.0031 17.5 0.2 3.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EON98786.1 - 0.0046 17.1 0.8 2.4 8.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EON98786.1 - 0.0049 16.9 1.7 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EON98786.1 - 0.0094 16.1 0.8 2.3 8.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type RRM_6 PF14259.1 EON98786.1 - 0.02 14.8 0.0 0.095 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MT0933_antitox PF14013.1 EON98786.1 - 0.042 13.9 1.2 0.042 13.9 0.8 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein RED_N PF07808.8 EON98786.1 - 2.1 7.5 9.6 0.043 13.0 0.6 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region Mpv17_PMP22 PF04117.7 EON98787.1 - 1.6e-14 53.2 0.1 2.7e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EON98789.1 - 2.6e-21 75.7 45.5 4.5e-14 51.9 22.5 3.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EON98789.1 - 2.1e-07 29.5 18.7 6.9e-07 27.8 12.6 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PMP1_2 PF08114.6 EON98789.1 - 0.12 11.8 0.2 0.12 11.8 0.1 3.5 4 0 0 4 4 4 0 ATPase proteolipid family Pox_A14 PF05767.7 EON98789.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.8 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF3817 PF12823.2 EON98789.1 - 1.4 9.4 0.0 1.4 9.4 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF3817) SRP-alpha_N PF04086.8 EON98790.1 - 6.2e-61 206.2 0.1 8.6e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EON98790.1 - 2.6e-53 180.4 0.2 4.4e-53 179.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EON98790.1 - 1.3e-06 28.4 0.2 5e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EON98790.1 - 7e-06 25.0 0.0 1.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EON98790.1 - 0.00011 21.6 0.2 0.00032 20.1 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EON98790.1 - 0.0071 16.0 0.3 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EON98790.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EON98790.1 - 0.048 13.9 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EON98790.1 - 0.082 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EON98790.1 - 0.095 12.8 0.1 2.1 8.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain T5orf172 PF10544.4 EON98791.1 - 4.2e-14 52.7 1.3 1e-13 51.5 0.9 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EON98791.1 - 2.5e-11 43.8 2.3 5.8e-11 42.7 1.6 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 HET PF06985.6 EON98792.1 - 3e-30 105.2 9.5 3e-30 105.2 6.6 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.3 EON98793.1 - 1.2e-26 92.6 15.7 9.3e-26 89.8 0.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Wbp11 PF09429.5 EON98794.1 - 1.7e-23 82.3 9.9 1.7e-23 82.3 6.9 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2294 PF10057.4 EON98794.1 - 0.00074 19.1 0.4 0.0012 18.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 EON98794.1 - 0.016 14.2 2.3 0.023 13.7 1.6 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 EON98794.1 - 0.2 10.9 2.8 0.31 10.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mcm10 PF09332.6 EON98794.1 - 1.7 7.9 7.4 3.3 6.9 5.1 1.4 1 0 0 1 1 1 0 Mcm10 replication factor MFS_1 PF07690.11 EON98795.1 - 1.6e-22 79.7 54.6 1.8e-15 56.5 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.4 EON98796.1 - 0.07 12.6 26.0 0.12 11.7 18.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EON98796.1 - 0.16 11.3 32.5 0.22 10.8 22.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal G-patch PF01585.18 EON98796.1 - 0.23 11.2 1.8 0.89 9.3 0.2 2.7 2 1 0 2 2 2 0 G-patch domain RR_TM4-6 PF06459.7 EON98796.1 - 0.28 11.0 10.2 0.31 10.8 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.6 EON98796.1 - 1 7.6 4.9 1 7.5 3.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1675 PF07897.6 EON98796.1 - 7.8 6.2 16.3 12 5.6 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SET PF00856.23 EON98797.1 - 2.9e-07 30.9 0.2 0.0026 18.0 0.0 3.1 2 1 1 3 3 3 2 SET domain Asp PF00026.18 EON98798.1 - 2.7e-63 214.1 3.8 3.4e-63 213.8 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON98798.1 - 5.6e-07 29.6 0.9 3e-06 27.2 0.3 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EON98798.1 - 0.0083 15.6 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PAP1 PF08601.5 EON98798.1 - 0.14 11.8 0.2 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 Asp_protease_2 PF13650.1 EON98798.1 - 0.17 12.4 1.0 42 4.7 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Yae1_N PF09811.4 EON98799.1 - 9.5e-15 53.8 1.8 1.7e-14 53.0 1.3 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Amidase PF01425.16 EON98801.1 - 3.4e-67 227.2 0.0 8.6e-67 225.8 0.0 1.6 1 1 0 1 1 1 1 Amidase Iso_dh PF00180.15 EON98802.1 - 2.9e-97 325.7 0.0 4.1e-97 325.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IF4E PF01652.13 EON98803.1 - 3.4e-59 199.0 0.0 4e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NGP1NT PF08153.7 EON98804.1 - 5e-47 159.0 0.9 8.5e-47 158.3 0.6 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EON98804.1 - 1.3e-19 70.2 0.1 1e-15 57.6 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EON98804.1 - 8.2e-06 25.7 1.6 0.041 13.7 0.0 4.0 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.13 EON98804.1 - 1.3e-05 24.4 0.0 4.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EON98804.1 - 0.0011 18.1 0.1 0.0074 15.4 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EON98804.1 - 0.0091 15.4 0.0 1.4 8.2 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EON98804.1 - 0.013 14.7 0.1 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family SusD-like_3 PF14322.1 EON98804.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane FMN_red PF03358.10 EON98805.1 - 1.7e-09 37.3 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EON98805.1 - 5.4e-08 32.9 0.1 1.4e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EON98805.1 - 0.00018 21.0 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EON98805.1 - 0.0054 16.7 0.0 0.43 10.5 0.0 2.2 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EON98805.1 - 0.025 13.9 0.1 0.16 11.3 0.1 2.0 1 1 0 1 1 1 0 Flavodoxin ADH_zinc_N PF00107.21 EON98806.1 - 3.5e-35 120.3 0.7 5.8e-35 119.6 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON98806.1 - 4.6e-13 50.1 0.5 8.7e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98806.1 - 1.3e-06 28.1 0.0 5.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EON98806.1 - 0.0079 15.7 2.2 0.13 11.8 0.8 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EON98806.1 - 0.042 13.8 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_22 PF13383.1 EON98807.1 - 3.2e-25 89.0 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EON98807.1 - 0.00018 21.5 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Ribosomal_S8 PF00410.14 EON98808.1 - 4.8e-27 94.3 0.0 5.8e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 CR6_interact PF10147.4 EON98809.1 - 0.0036 16.6 4.4 0.0036 16.6 3.0 1.8 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SKG6 PF08693.5 EON98809.1 - 0.015 14.5 0.9 0.036 13.3 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.6 EON98809.1 - 0.02 14.5 0.1 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Protocadherin DUF3040 PF11239.3 EON98809.1 - 0.18 11.8 0.9 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SSP160 PF06933.6 EON98809.1 - 4.8 5.0 8.6 9.1 4.1 5.9 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LPP20 PF02169.11 EON98809.1 - 6.5 6.9 10.1 0.91 9.6 1.1 2.7 2 1 0 2 2 2 0 LPP20 lipoprotein COXG PF06240.8 EON98810.1 - 0.044 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Profilin PF00235.14 EON98811.1 - 3.3e-11 43.3 0.0 4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Profilin GTP_EFTU PF00009.22 EON98812.1 - 3.1e-55 186.5 0.0 6.3e-55 185.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EON98812.1 - 1.1e-31 108.5 0.0 2e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EON98812.1 - 1.5e-31 108.4 0.0 3.1e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EON98812.1 - 7.4e-21 73.8 0.0 1.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EON98812.1 - 7.2e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF3933 PF13069.1 EON98812.1 - 0.072 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) MMR_HSR1 PF01926.18 EON98812.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Bac_luciferase PF00296.15 EON98813.1 - 5.4e-51 173.5 0.0 6.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AMP-binding PF00501.23 EON98815.1 - 1.7e-19 69.5 0.1 2.1e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON98815.1 - 3.3e-11 43.9 0.1 5.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_3 PF13469.1 EON98816.1 - 5.1e-09 37.2 0.6 8.4e-09 36.5 0.4 1.4 1 0 0 1 1 1 1 Sulfotransferase family ADH_N PF08240.7 EON98817.1 - 2.8e-12 46.3 0.0 4.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON98817.1 - 3.1e-10 39.7 0.3 5.1e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF726 PF05277.7 EON98818.1 - 2.5e-112 375.2 0.2 3.3e-112 374.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EON98818.1 - 1.6e-05 24.8 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EON98818.1 - 2.2e-05 24.7 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EON98818.1 - 0.0038 16.9 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EON98818.1 - 0.0084 15.7 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Cutinase PF01083.17 EON98818.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase PE-PPE PF08237.6 EON98818.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Gly-zipper_OmpA PF13436.1 EON98818.1 - 5.1 6.7 12.0 28 4.4 0.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Phostensin_N PF13916.1 EON98819.1 - 0.047 13.6 3.8 0.13 12.2 0.8 2.8 2 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal His_Phos_1 PF00300.17 EON98820.1 - 5.9e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2613 PF11021.3 EON98821.1 - 3.4 7.4 11.6 0.19 11.4 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Med1 PF10744.4 EON98822.1 - 1.8e-43 148.8 0.0 9.6e-43 146.4 0.0 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 BSD PF03909.12 EON98823.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 BSD domain Urotensin_II PF02083.10 EON98823.1 - 1.4 8.3 4.6 0.4 10.1 1.1 1.7 2 0 0 2 2 2 0 Urotensin II Coatomer_WDAD PF04053.9 EON98825.1 - 2.3e-170 567.1 0.0 5e-170 566.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EON98825.1 - 2.1e-27 93.9 13.8 3.5e-10 39.3 0.1 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EON98825.1 - 0.0063 16.2 0.0 2.8 7.7 0.0 3.9 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EON98825.1 - 0.18 9.8 2.8 7 4.6 0.0 3.8 3 1 0 4 4 4 0 Nucleoporin Nup120/160 HD_3 PF13023.1 EON98826.1 - 4.9e-47 159.7 0.0 6.4e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EON98826.1 - 0.0015 18.5 0.1 0.0036 17.2 0.0 1.8 1 1 0 1 1 1 1 HD domain EHN PF06441.7 EON98828.1 - 3.8e-39 133.0 0.8 3.6e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EON98828.1 - 8.5e-13 48.7 1.8 2e-12 47.4 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON98828.1 - 1.2e-05 25.0 0.1 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold TTSSLRR PF12468.3 EON98829.1 - 0.68 9.5 3.4 0.64 9.5 0.7 2.1 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Sugar_tr PF00083.19 EON98830.1 - 7.6e-90 301.6 23.6 9.3e-90 301.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98830.1 - 2.8e-37 128.2 45.8 6e-32 110.7 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EON98830.1 - 2.6e-05 23.9 3.3 0.009 15.7 0.1 4.1 3 1 1 4 4 4 1 MFS_1 like family DUF1228 PF06779.9 EON98830.1 - 0.0018 18.2 3.0 0.0055 16.6 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Folate_carrier PF01770.13 EON98830.1 - 0.021 13.3 0.2 0.021 13.3 0.1 1.6 2 0 0 2 2 2 0 Reduced folate carrier TRI12 PF06609.8 EON98830.1 - 0.073 11.2 7.8 1.2 7.2 0.0 2.4 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyoxalase PF00903.20 EON98831.1 - 5.1e-09 36.1 5.6 4e-07 30.0 1.3 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EON98831.1 - 0.04 13.9 0.2 0.4 10.7 0.1 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Thioredoxin PF00085.15 EON98832.1 - 5.2e-22 77.4 0.1 5.9e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EON98832.1 - 5.3e-09 36.0 0.0 8.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EON98832.1 - 1.5e-06 28.3 0.4 2.6e-05 24.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EON98832.1 - 0.00013 21.8 0.1 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EON98832.1 - 0.0012 18.3 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EON98832.1 - 0.0069 16.0 0.1 0.012 15.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 EON98832.1 - 0.019 13.6 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.5 EON98832.1 - 0.021 14.3 0.2 0.03 13.8 0.1 1.3 1 1 0 1 1 1 0 Redoxin HyaE PF07449.6 EON98832.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EON98832.1 - 0.14 11.9 0.2 0.45 10.3 0.1 1.9 2 1 0 2 2 2 0 Thioredoxin domain DUF1304 PF06993.7 EON98834.1 - 3e-39 133.2 3.6 3.6e-39 132.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Oleosin PF01277.12 EON98834.1 - 4.5 6.8 6.7 8.3 6.0 0.1 2.2 2 0 0 2 2 2 0 Oleosin LMWPc PF01451.16 EON98835.1 - 0.00039 20.7 0.0 0.67 10.2 0.0 2.5 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase RNA_pol_Rpb4 PF03874.11 EON98835.1 - 0.036 14.0 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Gluconate_2-dh3 PF13618.1 EON98835.1 - 0.046 13.8 0.2 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 adh_short PF00106.20 EON98836.1 - 6.7e-11 42.3 0.0 8e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON98836.1 - 0.00064 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON98836.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_26 PF13659.1 EON98836.1 - 0.094 12.7 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Thioesterase PF00975.15 EON98837.1 - 3.3e-30 106.0 0.0 7.8e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.23 EON98837.1 - 2.5e-16 59.0 0.0 3.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EON98837.1 - 7.3e-09 35.7 3.4 7.6e-09 35.7 1.2 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EON98837.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EON98838.1 - 1.2e-22 80.3 0.0 1.3e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EON98838.1 - 9.5e-05 22.1 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family GATase PF00117.23 EON98839.1 - 1.2e-36 126.0 0.0 3.6e-36 124.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EON98839.1 - 1.8e-31 107.7 0.0 4.4e-31 106.4 0.0 1.7 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EON98839.1 - 8.3e-07 28.1 0.0 0.00084 18.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EON98839.1 - 1.4e-06 27.9 0.0 4.4e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.11 EON98839.1 - 0.21 10.1 0.0 0.43 9.0 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_61 PF03443.9 EON98840.1 - 8.4e-59 199.0 0.1 1e-58 198.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mannitol_dh_C PF08125.8 EON98841.1 - 2.8e-47 160.9 0.5 3.7e-47 160.5 0.3 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EON98841.1 - 3.6e-22 78.9 0.5 2e-21 76.5 0.0 2.3 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EON98841.1 - 0.0035 16.7 0.9 0.0077 15.6 0.2 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nitro_FeMo-Co PF02579.12 EON98841.1 - 0.062 13.3 0.6 5 7.2 0.0 3.2 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor MARVEL PF01284.18 EON98842.1 - 0.0019 18.0 8.0 0.0024 17.7 5.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain EpsG PF14897.1 EON98842.1 - 0.0039 16.1 8.9 0.0046 15.9 6.2 1.0 1 0 0 1 1 1 1 EpsG family NfeD PF01957.13 EON98842.1 - 0.025 14.7 1.2 0.025 14.7 0.8 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding T2SF PF00482.18 EON98842.1 - 0.28 11.0 3.7 0.084 12.7 0.6 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Abhydrolase_9_N PF15420.1 EON98842.1 - 0.33 10.6 6.3 0.39 10.4 4.4 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Tetraspannin PF00335.15 EON98842.1 - 0.4 9.9 8.6 0.56 9.4 5.9 1.4 1 1 0 1 1 1 0 Tetraspanin family MpPF26 PF07666.6 EON98842.1 - 1 9.2 14.7 1.6 8.6 10.1 1.4 1 1 0 1 1 1 0 M penetrans paralogue family 26 zf-DHHC PF01529.15 EON98842.1 - 1.1 8.6 6.3 1.1 8.6 3.9 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase Rifin_STEVOR PF02009.11 EON98842.1 - 1.1 8.8 4.0 1.5 8.4 2.8 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF4064 PF13273.1 EON98842.1 - 1.2 9.3 14.7 0.018 15.1 2.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) TMEM154 PF15102.1 EON98842.1 - 4.1 7.0 5.4 0.46 10.1 0.4 1.8 2 0 0 2 2 2 0 TMEM154 protein family DSPc PF00782.15 EON98843.1 - 3.4e-09 36.3 0.0 6.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EON98843.1 - 0.0038 17.4 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EON98843.1 - 0.0092 15.3 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CBM_6 PF03422.10 EON98844.1 - 2.9e-36 124.3 2.2 3.3e-36 124.2 1.6 1.0 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) p450 PF00067.17 EON98845.1 - 2.4e-32 112.0 0.0 2.3e-31 108.8 0.0 2.2 1 1 0 2 2 2 1 Cytochrome P450 DUF4404 PF14357.1 EON98845.1 - 0.2 12.1 0.5 1.5 9.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) ADH_N PF08240.7 EON98846.1 - 3.3e-31 107.2 0.4 1.2e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON98846.1 - 2.3e-13 49.8 0.4 9e-13 47.9 0.2 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EON98846.1 - 0.002 18.4 1.2 0.028 14.8 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON98846.1 - 0.041 12.3 0.3 0.065 11.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EON98846.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.19 EON98847.1 - 3.9e-105 352.0 33.3 4.9e-105 351.7 23.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98847.1 - 3.4e-24 85.2 34.7 1.2e-22 80.1 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EON98847.1 - 0.0084 14.5 32.0 0.025 12.9 1.7 3.8 2 2 1 3 3 3 2 MFS/sugar transport protein Peptidase_C12 PF01088.16 EON98848.1 - 5.6e-59 198.8 0.0 6.3e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pectate_lyase_3 PF12708.2 EON98849.1 - 9.9e-07 29.1 0.2 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein Acid_PPase PF12689.2 EON98850.1 - 5.1e-56 188.9 0.0 1.4e-55 187.4 0.0 1.7 1 1 0 1 1 1 1 Acid Phosphatase MFS_1 PF07690.11 EON98852.1 - 3.5e-15 55.5 17.1 3.9e-15 55.4 11.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON98852.1 - 0.00014 21.3 1.7 0.00029 20.3 1.2 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 EON98852.1 - 0.042 13.6 1.1 0.55 10.0 0.2 2.7 3 0 0 3 3 3 0 MFS_1 like family MFS_2 PF13347.1 EON98852.1 - 0.12 10.7 15.7 0.022 13.1 0.6 2.5 1 1 0 2 2 2 0 MFS/sugar transport protein Peptidase_A24 PF01478.13 EON98852.1 - 8.3 6.6 9.2 0.44 10.7 1.3 2.4 2 1 0 2 2 2 0 Type IV leader peptidase family DUF1485 PF07364.7 EON98853.1 - 1.2e-74 251.1 0.7 1.8e-74 250.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 EON98853.1 - 1.7e-41 141.6 0.0 3.3e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 MlrC C-terminus CBM_19 PF03427.8 EON98853.1 - 0.0002 21.0 6.3 0.00099 18.8 4.4 2.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Glyco_hydro_61 PF03443.9 EON98853.1 - 0.0071 16.1 0.4 0.16 11.7 0.1 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 Reo_sigmaC PF04582.7 EON98854.1 - 3.8e-07 29.5 28.2 2e-06 27.2 2.9 4.1 1 1 2 4 4 4 2 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EON98854.1 - 7.7e-05 22.4 5.1 7.7e-05 22.4 3.5 7.9 1 1 6 8 8 7 3 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.1 EON98854.1 - 0.0028 17.1 11.0 0.0028 17.1 7.6 6.5 1 1 6 7 7 6 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 EON98854.1 - 0.0064 16.4 4.0 0.0064 16.4 2.7 10.3 6 2 5 11 11 11 3 bZIP transcription factor IncA PF04156.9 EON98854.1 - 0.0067 16.0 105.8 0.014 14.9 15.8 5.8 1 1 3 4 4 4 2 IncA protein CENP-F_leu_zip PF10473.4 EON98854.1 - 0.019 14.7 104.6 0.026 14.3 17.3 6.0 1 1 5 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EON98854.1 - 0.045 11.4 100.7 0.78 7.3 10.3 3.8 1 1 2 3 3 3 0 Myosin tail HALZ PF02183.13 EON98854.1 - 0.054 13.2 0.1 0.054 13.2 0.1 9.6 6 3 4 10 10 10 0 Homeobox associated leucine zipper ERM PF00769.14 EON98854.1 - 0.31 10.5 106.3 0.15 11.5 19.3 5.1 1 1 3 4 4 4 0 Ezrin/radixin/moesin family GAS PF13851.1 EON98854.1 - 0.34 10.0 93.0 0.058 12.5 10.0 6.5 2 1 3 6 6 6 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EON98854.1 - 1.1 8.9 103.8 0.57 9.9 13.6 7.2 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.6 EON98854.1 - 1.9 8.2 15.5 12 5.7 0.0 5.9 5 2 1 6 6 6 0 Shugoshin N-terminal coiled-coil region Rhodanese PF00581.15 EON98855.1 - 5e-16 59.0 0.0 6.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3722 PF12519.3 EON98855.1 - 0.088 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Abhydrolase_6 PF12697.2 EON98856.1 - 3.7e-15 56.4 1.0 4.8e-15 56.0 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON98856.1 - 0.0004 20.1 0.0 0.00054 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON98856.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold CRAL_TRIO PF00650.15 EON98857.1 - 1.5e-25 89.5 0.0 2.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EON98857.1 - 5.6e-11 42.3 0.1 1.4e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UPF0121 PF03661.8 EON98858.1 - 4.7e-05 22.6 4.2 0.00012 21.4 2.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) YGGT PF02325.12 EON98858.1 - 1.7 8.6 11.9 0.24 11.3 0.4 3.4 3 0 0 3 3 3 0 YGGT family Amidohydro_2 PF04909.9 EON98859.1 - 6.2e-37 127.6 0.3 7.4e-37 127.3 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EON98860.1 - 2.9e-15 55.8 59.6 2.1e-14 53.0 36.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily tRNA-synt_2 PF00152.15 EON98861.1 - 9.1e-47 159.4 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Sugar_tr PF00083.19 EON98862.1 - 1.1e-64 218.6 32.3 1.3e-64 218.4 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98862.1 - 7.9e-14 51.1 41.4 9.9e-14 50.8 24.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PIP5K PF01504.13 EON98863.1 - 5.5e-86 287.7 0.1 8.5e-86 287.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sugar_tr PF00083.19 EON98864.1 - 1.1e-84 284.6 21.0 1.3e-84 284.3 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON98864.1 - 1.2e-26 93.2 21.8 1.2e-26 93.2 15.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EON98864.1 - 8.8e-08 30.7 1.9 1.6e-07 29.9 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_28 PF00295.12 EON98865.1 - 1.1e-14 54.1 0.9 5.6e-13 48.5 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Sporozoite_P67 PF05642.6 EON98865.1 - 0.32 8.8 2.0 0.29 8.9 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myb_DNA-binding PF00249.26 EON98868.1 - 3.4e-12 46.2 4.6 1e-05 25.4 0.7 3.7 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EON98868.1 - 9.3e-10 38.4 4.4 2e-06 27.8 0.4 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EON98868.1 - 1.5e-05 25.0 0.4 1.5e-05 25.0 0.3 2.8 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain PriCT_2 PF08707.6 EON98868.1 - 0.019 14.8 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) RIO1 PF01163.17 EON98869.1 - 0.04 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FAD_binding_3 PF01494.14 EON98870.1 - 1.5e-12 47.2 0.1 7.6e-10 38.3 0.0 2.9 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON98870.1 - 1.8e-05 23.8 0.0 4.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON98870.1 - 0.017 14.0 0.0 0.031 13.2 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein SYS1 PF09801.4 EON98871.1 - 5.8e-49 165.8 5.4 6.7e-49 165.6 3.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network FUSC-like PF12805.2 EON98871.1 - 0.42 9.4 5.5 0.71 8.7 0.3 2.1 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS TrbE PF11100.3 EON98871.1 - 9 6.2 9.6 0.34 10.7 0.8 2.3 2 1 0 2 2 2 0 Conjugal transfer protein TrbE adh_short PF00106.20 EON98872.1 - 2.5e-06 27.5 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON98872.1 - 0.044 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase COX6B PF02297.12 EON98873.1 - 8.5e-24 83.3 3.4 1.1e-23 82.9 2.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EON98873.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Phage_terminase PF10668.4 EON98873.1 - 0.12 12.2 0.4 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Phage terminase small subunit Tyrosinase PF00264.15 EON98874.1 - 3.4e-33 115.6 0.2 4.5e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2263 PF10021.4 EON98875.1 - 3.6e-16 59.4 0.0 6.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Laminin_G_3 PF13385.1 EON98875.1 - 0.0076 16.4 0.1 0.02 15.1 0.0 1.7 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily GMC_oxred_N PF00732.14 EON98876.1 - 5.4e-51 173.4 0.0 7.3e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EON98876.1 - 9.6e-40 136.1 0.0 1.6e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON98876.1 - 9.4e-07 28.0 0.1 0.015 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EON98876.1 - 2.4e-06 26.6 0.2 0.00013 20.9 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON98876.1 - 1.1e-05 25.3 0.1 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EON98876.1 - 3e-05 23.0 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EON98876.1 - 0.01 14.5 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EON98876.1 - 0.012 15.7 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON98876.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON98876.1 - 0.057 13.1 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EON98876.1 - 0.073 13.4 0.1 0.69 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Linker_histone PF00538.14 EON98877.1 - 1.4e-24 85.9 0.4 3.2e-24 84.7 0.3 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family AF-4 PF05110.8 EON98877.1 - 0.021 12.7 30.1 0.022 12.6 20.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S8 PF00082.17 EON98880.1 - 0.00047 19.3 0.2 0.00057 19.1 0.2 1.1 1 0 0 1 1 1 1 Subtilase family CPSF100_C PF13299.1 EON98881.1 - 9.3e-44 149.4 0.3 2.6e-43 147.9 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EON98881.1 - 5.9e-26 90.8 0.0 1.8e-25 89.2 0.0 1.8 1 1 1 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EON98881.1 - 1.8e-07 30.8 0.0 4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EON98881.1 - 0.023 14.3 0.1 0.099 12.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 EON98882.1 - 1.8e-40 138.7 25.6 2.1e-40 138.5 17.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EON98882.1 - 0.14 11.6 9.5 0.074 12.5 3.6 2.5 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EON98884.1 - 4.8e-18 65.0 8.0 3.8e-16 58.7 5.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON98884.1 - 4.7e-05 22.1 1.1 0.00015 20.4 0.1 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter DUF3792 PF12670.2 EON98884.1 - 0.13 12.1 0.4 0.13 12.1 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF3328 PF11807.3 EON98885.1 - 2.5e-53 180.9 0.2 3.4e-53 180.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 EON98886.1 - 4.2e-21 74.9 0.6 5.7e-21 74.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EON98886.1 - 7.1e-09 35.4 11.8 1.1e-08 34.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EON98886.1 - 0.041 13.5 4.6 0.12 12.1 3.2 1.9 1 0 0 1 1 1 0 AT hook motif O-FucT PF10250.4 EON98887.1 - 9e-05 21.7 0.0 0.002 17.3 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NmrA PF05368.8 EON98888.1 - 3.4e-33 114.8 0.0 4.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98888.1 - 1.8e-10 41.1 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON98888.1 - 0.00058 19.3 0.1 0.0025 17.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EON98888.1 - 0.0011 19.2 0.1 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EON98888.1 - 0.0012 18.5 0.1 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EON98888.1 - 0.0016 18.3 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CoA_binding PF02629.14 EON98888.1 - 0.13 12.7 0.1 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Methyltransf_11 PF08241.7 EON98890.1 - 5.7e-11 42.7 0.0 9.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98890.1 - 7.4e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON98890.1 - 1.9e-10 41.0 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON98890.1 - 3.2e-08 33.2 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON98890.1 - 5.1e-08 33.1 0.0 1.2e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98890.1 - 1.5e-06 28.7 0.0 2.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON98890.1 - 6e-06 25.5 0.1 1.2e-05 24.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EON98890.1 - 0.0019 17.5 0.1 0.0042 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EON98890.1 - 0.0081 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EON98890.1 - 0.038 13.2 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain CMAS PF02353.15 EON98890.1 - 0.071 12.1 0.3 0.14 11.2 0.2 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EON98890.1 - 0.09 12.4 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sec23_trunk PF04811.10 EON98891.1 - 1.9e-56 191.1 0.0 4.2e-56 190.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EON98891.1 - 2.2e-23 81.6 0.0 3.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EON98891.1 - 1.8e-18 66.8 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EON98891.1 - 2.6e-16 58.8 5.3 5.6e-16 57.8 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EON98891.1 - 1.2e-05 24.8 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 EON98891.1 - 0.049 13.0 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Cytidylate_kin PF02224.13 EON98891.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Aldedh PF00171.17 EON98892.1 - 2.6e-159 530.4 0.3 3e-159 530.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_16 PF13191.1 EON98893.1 - 0.00014 21.8 2.8 0.0039 17.2 1.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EON98893.1 - 0.0029 17.3 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EON98893.1 - 0.0031 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EON98893.1 - 0.015 14.7 0.1 0.072 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON98893.1 - 0.033 14.3 0.2 0.1 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EON98893.1 - 0.063 12.7 0.5 0.16 11.3 0.0 1.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Miro PF08477.8 EON98893.1 - 0.095 13.2 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ABC2_membrane PF01061.19 EON98894.1 - 1.8e-23 82.7 21.1 2.6e-23 82.2 14.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EON98894.1 - 2.1e-13 50.7 0.0 4.1e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EON98894.1 - 2.4e-05 24.4 0.0 6.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EON98894.1 - 0.0047 16.8 0.1 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EON98894.1 - 0.038 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EON98894.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 EON98894.1 - 1.2 8.0 30.4 0.28 10.1 12.4 2.5 3 0 0 3 3 3 0 ABC-2 family transporter protein Myotub-related PF06602.9 EON98896.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ribonuc_L-PSP PF01042.16 EON98897.1 - 1.1e-11 44.5 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CBM-like PF14683.1 EON98898.1 - 1.3e-10 41.2 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EON98898.1 - 3.9e-07 30.1 1.1 6.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II PDZ_1 PF12812.2 EON98899.1 - 6.1e-55 183.0 0.0 4.1e-34 116.3 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EON98899.1 - 4.5e-15 55.3 0.2 1.9e-06 27.6 0.1 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EON98899.1 - 1.2e-14 54.3 0.1 2.8e-13 49.9 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EON98899.1 - 5.9e-09 35.9 0.0 0.00088 19.4 0.0 4.3 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EON98899.1 - 8.7e-05 22.2 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EON98899.1 - 0.0025 17.5 0.6 0.093 12.5 0.2 3.2 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EON98899.1 - 0.17 11.2 0.3 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EON98899.1 - 0.28 10.4 0.7 0.44 9.8 0.5 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EON98899.1 - 0.84 7.9 0.8 1.2 7.4 0.2 1.4 2 0 0 2 2 2 0 Peptidase S46 Lactonase PF10282.4 EON98900.1 - 3.1e-65 220.5 2.0 6.3e-54 183.3 0.1 2.9 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller TGT PF01702.13 EON98901.1 - 3.4e-85 285.1 0.0 4.2e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Sulf_transp PF04143.9 EON98902.1 - 5.4e-11 42.3 27.7 4.5e-08 32.9 7.3 5.5 4 2 2 6 6 6 2 Sulphur transport DUF4341 PF14241.1 EON98902.1 - 0.0015 18.1 7.3 0.0015 18.1 5.0 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF4341) GATA PF00320.22 EON98903.1 - 6.9e-15 54.1 2.5 1.4e-14 53.1 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TPR_MLP1_2 PF07926.7 EON98903.1 - 0.00032 20.4 0.1 4.6 6.9 4.2 2.3 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 EON98903.1 - 0.011 14.0 2.7 0.015 13.6 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 EON98903.1 - 0.015 14.3 4.6 0.045 12.7 3.6 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EON98903.1 - 0.035 13.9 10.9 5.6 6.8 0.0 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TF_Zn_Ribbon PF08271.7 EON98903.1 - 0.074 12.3 0.4 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2630 PF10944.3 EON98903.1 - 0.077 13.1 5.9 0.12 12.5 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DUF342 PF03961.8 EON98903.1 - 0.14 10.5 2.4 0.19 10.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 EON98903.1 - 0.28 11.0 11.8 0.088 12.6 5.4 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Erp_C PF06780.6 EON98903.1 - 1.5 8.6 6.9 2.1 8.1 3.9 1.8 1 1 1 2 2 2 0 Erp protein C-terminus IFP_35_N PF07334.8 EON98903.1 - 3.6 7.6 6.9 0.61 10.1 1.1 2.6 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ADIP PF11559.3 EON98903.1 - 4.6 7.1 12.3 1.4 8.8 6.2 1.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Hist_deacetyl PF00850.14 EON98904.1 - 1.6e-53 182.0 0.4 1.9e-53 181.8 0.2 1.0 1 0 0 1 1 1 1 Histone deacetylase domain SRP54 PF00448.17 EON98905.1 - 3.6e-07 29.8 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EON98905.1 - 2.8e-06 28.1 0.0 8.4e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON98905.1 - 0.00012 22.4 0.0 0.00058 20.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EON98905.1 - 0.00028 20.0 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EON98905.1 - 0.00031 20.3 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EON98905.1 - 0.00037 20.1 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EON98905.1 - 0.00038 19.5 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 EON98905.1 - 0.00048 20.1 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EON98905.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EON98905.1 - 0.0023 16.7 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 EON98905.1 - 0.0035 17.5 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EON98905.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EON98905.1 - 0.0092 15.6 0.1 0.025 14.2 0.1 1.7 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EON98905.1 - 0.01 15.5 0.1 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 EON98905.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON98905.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EON98905.1 - 0.021 14.5 0.3 0.11 12.2 0.0 2.1 1 1 1 2 2 2 0 Part of AAA domain AAA_31 PF13614.1 EON98905.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EON98905.1 - 0.033 14.1 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EON98905.1 - 0.033 13.5 0.1 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.12 EON98905.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EON98905.1 - 0.043 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArsA_ATPase PF02374.10 EON98905.1 - 0.054 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase DUF3747 PF12565.3 EON98905.1 - 0.063 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) ABC_tran PF00005.22 EON98905.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 EON98905.1 - 0.066 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EON98905.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EON98905.1 - 0.11 11.9 0.3 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EON98905.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EON98905.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ACC_epsilon PF13822.1 EON98905.1 - 0.72 10.2 4.5 1.6 9.1 0.0 2.9 3 0 0 3 3 2 0 Acyl-CoA carboxylase epsilon subunit Mit_KHE1 PF10173.4 EON98906.1 - 2.1e-62 210.3 0.4 2.1e-62 210.3 0.3 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF4363 PF14276.1 EON98906.1 - 2.4 7.8 4.4 0.4 10.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Med2 PF11214.3 EON98906.1 - 4.7 7.2 8.1 1.5 8.8 3.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 Hexokinase_1 PF00349.16 EON98907.1 - 1.5e-24 86.4 0.0 2.6e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EON98907.1 - 4.8e-21 75.0 0.0 1e-20 73.9 0.0 1.6 2 0 0 2 2 2 1 Hexokinase FmdA_AmdA PF03069.10 EON98908.1 - 1.6e-41 142.2 0.0 1.1e-23 83.5 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family Cofilin_ADF PF00241.15 EON98909.1 - 8.8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Tax PF02959.11 EON98909.1 - 0.096 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 HTLV Tax RIO1 PF01163.17 EON98910.1 - 2.3e-41 141.2 0.1 2.3e-28 98.8 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EON98910.1 - 9.8e-32 108.8 0.0 2.2e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EON98910.1 - 2.3e-06 27.5 0.0 0.011 15.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EON98910.1 - 4.2e-06 25.9 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.1 EON98910.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain Poxvirus_B22R_N PF13169.1 EON98911.1 - 0.043 14.0 2.1 0.084 13.0 1.4 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal PP2C PF00481.16 EON98912.1 - 5.6e-29 101.2 0.0 9.4e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PC_rep PF01851.17 EON98913.1 - 3.1e-21 74.3 18.7 7e-05 22.8 0.1 9.4 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EON98913.1 - 1.7e-09 37.8 0.5 0.0001 22.5 0.1 4.1 3 0 0 3 3 3 2 HEAT repeats ADH_zinc_N PF00107.21 EON98914.1 - 9.1e-22 77.0 0.1 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON98914.1 - 8.4e-09 36.3 0.1 2.4e-08 34.8 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON98914.1 - 3.8e-06 26.6 0.0 6.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EON98914.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 EON98915.1 - 8.3e-35 120.1 0.1 2.1e-34 118.7 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON98915.1 - 7.9e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EON98915.1 - 5.3e-05 22.0 0.0 7.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EON98915.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EON98915.1 - 0.02 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain G-alpha PF00503.15 EON98916.1 - 2e-128 428.4 2.4 2.4e-128 428.1 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EON98916.1 - 1.3e-15 57.0 0.4 2.7e-10 39.7 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EON98916.1 - 0.0015 19.0 0.3 1.3 9.5 0.1 2.8 3 0 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 EON98916.1 - 0.0026 16.9 5.8 0.15 11.2 0.1 3.2 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EON98916.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Penicil_amidase PF01804.13 EON98916.1 - 0.075 12.0 0.0 2.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Penicillin amidase DIM1 PF02966.11 EON98917.1 - 1e-70 235.4 0.2 1.1e-70 235.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EON98917.1 - 0.013 15.5 0.2 0.026 14.6 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Ras PF00071.17 EON98918.1 - 1.9e-59 199.6 0.2 2.3e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON98918.1 - 6.8e-19 68.5 0.0 9.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON98918.1 - 3.5e-08 32.8 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EON98918.1 - 5.7e-07 29.1 0.1 3.1e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EON98918.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EON98918.1 - 0.0043 16.3 0.0 0.0085 15.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EON98918.1 - 0.017 14.2 0.1 0.023 13.8 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EON98918.1 - 0.041 13.2 0.6 0.69 9.3 0.1 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EON98918.1 - 0.044 12.9 0.1 0.091 11.9 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EON98918.1 - 0.047 13.2 1.7 0.54 9.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EON98918.1 - 0.097 12.5 0.4 1.6 8.6 0.3 2.6 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EON98920.1 - 2.4e-20 72.5 0.0 4.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4306 PF14154.1 EON98920.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) RPA_C PF08784.6 EON98921.1 - 1.2e-23 83.4 0.4 1.2e-23 83.4 0.3 1.6 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EON98921.1 - 1.9e-10 40.4 0.3 4.2e-10 39.3 0.1 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EON98921.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain HTH_Tnp_Tc5 PF03221.11 EON98922.1 - 7.9e-07 28.7 0.0 0.0012 18.5 0.0 3.3 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain PHP PF02811.14 EON98923.1 - 2e-09 37.4 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 PHP domain Npa1 PF11707.3 EON98924.1 - 3.7e-77 259.5 0.0 5.9e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal ParA PF10609.4 EON98925.1 - 7.3e-35 118.7 0.0 1.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EON98925.1 - 4.3e-13 49.1 0.0 6.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EON98925.1 - 7.1e-05 22.7 0.0 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EON98925.1 - 0.0001 21.4 0.4 0.0018 17.4 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EON98925.1 - 0.0014 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EON98925.1 - 0.0062 15.6 0.0 0.016 14.3 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 EON98925.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EON98925.1 - 0.017 14.8 0.1 0.29 10.9 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_26 PF13500.1 EON98925.1 - 0.019 14.5 0.0 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EON98925.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EON98925.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain VirE PF05272.6 EON98925.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Fer4_NifH PF00142.13 EON98925.1 - 0.15 11.2 0.0 0.84 8.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zn_Tnp_IS1595 PF12760.2 EON98925.1 - 0.21 11.4 0.1 0.21 11.4 0.0 1.9 2 0 0 2 2 1 0 Transposase zinc-ribbon domain Sec1 PF00995.18 EON98926.1 - 5.2e-33 114.5 0.2 6.3e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Phosphorylase PF00343.15 EON98927.1 - 0 1074.1 0.0 0 1073.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EON98927.1 - 0.086 12.5 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform TFCD_C PF12612.3 EON98928.1 - 1.8e-22 79.7 0.0 2.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal UPF0179 PF03684.8 EON98928.1 - 0.082 12.4 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) DUF500 PF04366.7 EON98929.1 - 3.2e-33 113.8 0.0 5.3e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) MoCF_biosynth PF00994.19 EON98930.1 - 3.6e-30 104.2 0.0 5.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DcpS_C PF11969.3 EON98932.1 - 1.1e-31 109.4 0.1 1.9e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EON98932.1 - 5.6e-28 97.5 0.0 9.3e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal His_Phos_2 PF00328.17 EON98933.1 - 5.3e-131 437.0 0.3 7.1e-131 436.6 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EON98933.1 - 2.7e-07 30.2 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF1777 PF08648.7 EON98934.1 - 4.5 6.9 27.0 0.28 10.9 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Avl9 PF09794.4 EON98935.1 - 9e-90 300.8 0.1 3.3e-54 183.8 0.0 3.1 1 1 2 3 3 3 3 Transport protein Avl9 SPA PF08616.5 EON98935.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Pou PF00157.12 EON98936.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain ECM11 PF15463.1 EON98937.1 - 5e-41 140.2 0.4 5e-41 140.2 0.3 1.8 2 1 0 2 2 2 1 Extracellular mutant protein 11 Thymidylat_synt PF00303.14 EON98937.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate synthase TIR PF01582.15 EON98937.1 - 0.078 12.4 0.1 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 TIR domain LIP PF03583.9 EON98938.1 - 1.2e-71 241.2 0.2 1.5e-71 240.9 0.1 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EON98938.1 - 0.00049 20.0 0.2 0.00071 19.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON98938.1 - 0.086 12.5 2.0 0.071 12.8 0.3 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 EON98938.1 - 0.1 12.3 0.1 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Cutinase Acetyltransf_7 PF13508.1 EON98940.1 - 7.4e-10 38.8 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EON98940.1 - 9.7e-07 28.6 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EON98940.1 - 1.1e-06 28.5 0.1 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EON98940.1 - 0.0003 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EON98940.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON98940.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF676 PF05057.9 EON98941.1 - 6.1e-06 25.6 0.1 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3886 PF13025.1 EON98941.1 - 0.054 13.4 2.0 0.096 12.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) BRO1 PF03097.13 EON98942.1 - 5.3e-134 446.6 1.2 5.3e-134 446.6 0.9 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EON98942.1 - 3.4e-96 321.7 17.2 7.4e-96 320.5 11.9 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1932 PF09130.6 EON98942.1 - 0.22 11.2 1.6 1.5 8.6 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1932) DUF3012 PF11216.3 EON98942.1 - 0.31 10.7 1.2 0.84 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) DUF948 PF06103.6 EON98942.1 - 0.55 10.1 6.1 9.5 6.1 0.4 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 EON98942.1 - 2.4 8.1 6.9 0.76 9.7 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lon_C PF05362.8 EON98943.1 - 2.2e-67 226.3 0.3 5e-67 225.1 0.2 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EON98943.1 - 1e-29 103.6 0.0 2.6e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EON98943.1 - 2.7e-23 82.6 0.0 7.4e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EON98943.1 - 2.6e-09 36.9 0.0 7.4e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EON98943.1 - 2.3e-08 33.6 0.0 4.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EON98943.1 - 1.7e-06 28.1 0.1 7.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EON98943.1 - 3e-05 24.8 0.0 0.0001 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EON98943.1 - 4.4e-05 23.0 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EON98943.1 - 4.7e-05 22.8 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EON98943.1 - 9.2e-05 21.5 0.1 0.00029 19.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EON98943.1 - 0.00021 21.4 0.0 0.0026 17.9 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EON98943.1 - 0.00071 19.5 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EON98943.1 - 0.0013 18.4 0.1 0.0062 16.2 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 EON98943.1 - 0.0023 17.7 0.0 0.006 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EON98943.1 - 0.0027 17.5 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EON98943.1 - 0.0046 15.7 0.2 0.013 14.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EON98943.1 - 0.0083 15.5 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EON98943.1 - 0.027 14.6 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EON98943.1 - 0.027 14.1 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EON98943.1 - 0.032 13.8 1.1 0.16 11.5 0.0 2.6 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EON98943.1 - 0.043 13.3 0.1 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EON98943.1 - 0.048 13.3 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EON98943.1 - 0.054 13.8 8.8 0.42 10.9 0.0 3.6 2 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EON98943.1 - 0.059 12.5 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EON98943.1 - 0.075 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EON98943.1 - 0.076 13.3 0.0 0.076 13.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain MFS_1 PF07690.11 EON98944.1 - 2.4e-05 23.2 40.4 0.00029 19.6 24.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2937 PF11157.3 EON98944.1 - 0.14 11.4 1.2 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Cullin PF00888.17 EON98945.1 - 1.3e-205 684.3 13.8 2.1e-205 683.7 9.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EON98945.1 - 8.2e-27 92.8 6.4 8.2e-27 92.8 4.5 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain FliL PF03748.9 EON98945.1 - 3.1 7.8 7.3 9.8 6.2 0.2 3.0 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL Glyco_hydro_76 PF03663.9 EON98946.1 - 5.9e-50 170.6 6.6 7.6e-50 170.3 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EON98946.1 - 0.069 11.4 0.0 3.5 5.7 0.0 2.0 1 1 1 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) GILT PF03227.11 EON98947.1 - 1.7e-14 53.5 0.1 2.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) FAD_binding_4 PF01565.18 EON98948.1 - 3.3e-25 88.1 0.7 5.3e-25 87.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Actin PF00022.14 EON98949.1 - 9.9e-14 50.5 0.0 3e-12 45.6 0.0 2.3 2 1 0 2 2 2 2 Actin Sugar_tr PF00083.19 EON98950.1 - 3.8e-25 88.3 0.0 4.4e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Claudin_3 PF06653.6 EON98950.1 - 0.064 12.9 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Utp21 PF04192.7 EON98951.1 - 3.4e-83 278.3 0.0 4.5e-83 277.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EON98951.1 - 8.2e-24 82.5 19.0 1.6e-05 24.5 0.1 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 EON98951.1 - 4.9e-06 24.9 0.2 0.96 7.5 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EON98951.1 - 3e-05 22.5 0.0 7e-05 21.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EON98951.1 - 0.025 13.3 0.0 0.83 8.3 0.0 2.6 2 0 0 2 2 2 0 Nup133 N terminal like adh_short PF00106.20 EON98952.1 - 1.6e-62 210.3 6.4 2.2e-31 108.9 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EON98952.1 - 1.9e-31 109.1 1.8 2.1e-15 56.8 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EON98952.1 - 7.3e-30 102.8 0.0 1.9e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain Epimerase PF01370.16 EON98952.1 - 2.2e-06 27.2 3.8 0.0018 17.7 0.1 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF4161 PF13722.1 EON98952.1 - 0.15 12.3 0.7 11 6.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) NUDIX PF00293.23 EON98953.1 - 3e-29 101.3 0.0 4.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.17 EON98954.1 - 2.4e-23 81.5 0.0 4.9e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON98954.1 - 2e-17 62.9 0.0 1.8e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON98954.1 - 0.0015 18.3 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.2 EON98955.1 - 2.6e-10 40.1 12.0 0.00019 21.5 0.6 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EON98955.1 - 3.7e-08 33.2 27.2 0.0089 16.3 0.7 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON98955.1 - 5.6e-08 32.5 18.2 0.0093 16.2 0.2 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EON98955.1 - 8.3e-08 32.1 12.6 0.0021 18.1 1.4 3.9 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EON98955.1 - 4.1e-07 29.6 15.5 0.00034 20.3 0.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EON98955.1 - 1.2e-06 28.5 14.8 0.17 12.2 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.2 EON98955.1 - 1.2e-05 25.3 15.6 0.049 13.7 0.8 4.0 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EON98955.1 - 0.0031 17.4 8.0 0.23 11.4 0.0 4.3 3 1 0 3 3 3 1 Zinc ribbon domain zf-Di19 PF05605.7 EON98955.1 - 0.0072 16.4 0.4 0.0072 16.4 0.3 3.3 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EON98955.1 - 0.0086 15.7 5.6 0.79 9.4 0.2 3.7 3 0 0 3 3 3 1 zinc-finger of a C2HC-type DUF1033 PF06279.6 EON98955.1 - 0.4 10.5 3.8 9.7 6.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) zinc-ribbons_6 PF07191.7 EON98955.1 - 0.68 9.7 11.9 2.2 8.1 0.7 4.2 3 1 1 4 4 4 0 zinc-ribbons DUF629 PF04780.7 EON98955.1 - 1.1 7.6 9.6 3.5 6.0 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF629) OSTMP1 PF09777.4 EON98955.1 - 2.8 7.0 9.1 3.4 6.7 1.1 2.8 2 2 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-FCS PF06467.9 EON98955.1 - 3.7 7.2 7.1 3.4 7.4 0.0 3.6 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif AKAP95 PF04988.7 EON98955.1 - 4.5 7.0 6.7 2.6 7.7 0.4 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Ribonuc_L-PSP PF01042.16 EON98956.1 - 8.4e-17 61.0 0.0 1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 EON98956.1 - 0.12 12.1 0.1 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1320) FAD_binding_1 PF00667.15 EON98957.1 - 2.8e-63 213.2 0.0 4.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EON98957.1 - 7.1e-35 120.1 0.2 1.5e-34 119.0 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EON98957.1 - 3.9e-21 75.6 0.1 4.9e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EON98957.1 - 0.01 15.8 0.0 0.042 13.8 0.0 2.1 1 0 0 1 1 1 0 Flavodoxin domain KH_1 PF00013.24 EON98958.1 - 0.0058 16.2 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EON98958.1 - 0.082 12.5 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 KH domain RR_TM4-6 PF06459.7 EON98958.1 - 2.5 7.9 8.4 3.2 7.5 5.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_4 PF12799.2 EON98959.1 - 0.0001 21.8 0.4 1.3 8.7 0.0 4.6 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EON98959.1 - 0.018 14.7 2.7 0.36 10.6 0.0 4.2 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 EON98959.1 - 0.019 14.5 0.1 0.13 11.9 0.1 2.4 2 0 0 2 2 2 0 F-box domain DNA_mis_repair PF01119.14 EON98961.1 - 1.9e-34 117.6 0.0 3.2e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EON98961.1 - 1.5e-13 50.5 0.0 2.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EON98961.1 - 9.9e-11 41.3 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans PF04082.13 EON98962.1 - 4.8e-09 35.4 5.5 7.3e-07 28.3 3.8 3.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain MOR2-PAG1_C PF14225.1 EON98963.1 - 3.1e-94 315.5 1.7 8.1e-94 314.2 0.4 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EON98963.1 - 2.9e-32 111.3 1.2 3.5e-18 64.6 0.1 2.2 2 0 0 2 2 2 2 Cell morphogenesis central region FAD_binding_3 PF01494.14 EON98964.1 - 1.6e-14 53.7 0.1 5.3e-14 52.0 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EON98964.1 - 0.0028 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SE PF08491.5 EON98964.1 - 0.0028 16.5 0.0 0.0068 15.2 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 EON98964.1 - 0.0089 14.9 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EON98964.1 - 0.06 13.1 0.1 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1924 PF09086.6 EON98964.1 - 0.12 12.4 0.0 7 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Ank_2 PF12796.2 EON98965.1 - 3.8e-34 116.9 0.1 6.9e-09 35.9 0.0 4.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EON98965.1 - 1.6e-27 93.8 7.6 1.4e-07 30.9 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EON98965.1 - 3.1e-27 93.9 5.9 7.7e-10 38.6 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON98965.1 - 1.4e-22 79.5 4.9 1.5e-06 28.5 0.0 6.6 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON98965.1 - 1.2e-14 52.9 4.5 0.02 15.0 0.0 7.2 9 0 0 9 9 9 3 Ankyrin repeat Big_3_4 PF13754.1 EON98965.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Cation_efflux PF01545.16 EON98966.1 - 1e-05 24.8 6.6 1.3e-05 24.4 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family Cupin_2 PF07883.6 EON98967.1 - 0.00018 20.9 0.2 0.0019 17.6 0.2 2.4 2 1 0 2 2 2 1 Cupin domain FTA2 PF13095.1 EON98968.1 - 7.4e-22 77.9 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 WH2 PF02205.15 EON98969.1 - 0.00031 20.2 1.1 0.00068 19.1 0.7 1.7 1 1 0 1 1 1 1 WH2 motif CAP_N PF01213.14 EON98969.1 - 0.012 14.8 0.2 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.14 EON98969.1 - 0.083 13.3 0.2 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein AdoMet_MTase PF07757.8 EON98971.1 - 1.8e-41 140.7 0.1 2.9e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EON98971.1 - 0.0047 16.6 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON98971.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON98971.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MLANA PF14991.1 EON98972.1 - 0.097 12.6 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein melan-A DUF2763 PF10961.3 EON98972.1 - 0.18 12.1 1.2 0.87 10.0 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2763) GTP_EFTU PF00009.22 EON98973.1 - 8.6e-57 191.6 0.1 1.3e-56 191.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EON98973.1 - 5.2e-36 122.7 0.2 1.4e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EON98973.1 - 1.7e-17 63.2 1.4 1.7e-17 63.2 1.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EON98973.1 - 0.00024 20.6 0.3 0.0006 19.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EON98973.1 - 0.00054 19.8 0.3 0.0016 18.3 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MAGE PF01454.14 EON98974.1 - 1.6e-44 151.6 0.0 2.2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family Lactamase_B PF00753.22 EON98975.1 - 7.3e-17 61.6 8.0 1.1e-16 61.0 5.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EON98975.1 - 9.9e-06 25.2 0.3 1.4e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain B12-binding PF02310.14 EON98975.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain ApbA PF02558.11 EON98976.1 - 1e-23 83.4 0.0 1.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EON98976.1 - 7.1e-14 51.8 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal TRP PF06011.7 EON98979.1 - 3.5e-96 322.4 23.8 4.1e-95 318.9 16.5 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EON98979.1 - 1.3e-28 99.7 0.0 2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF3328 PF11807.3 EON98980.1 - 5.1e-42 144.0 1.4 6.5e-42 143.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Med17 PF10156.4 EON98981.1 - 6.8e-83 278.5 5.1 8.4e-47 159.4 0.6 2.3 1 1 1 2 2 2 2 Subunit 17 of Mediator complex eIF-1a PF01176.14 EON98982.1 - 1.3e-27 94.9 0.2 1.9e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CBFD_NFYB_HMF PF00808.18 EON98983.1 - 1.9e-17 63.0 0.6 3.9e-17 62.0 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EON98983.1 - 0.0025 17.9 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CoatB PF10389.4 EON98984.1 - 0.14 12.0 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B HhH-GPD PF00730.20 EON98985.1 - 1.7e-07 31.5 0.0 3.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DEAD PF00270.24 EON98986.1 - 1e-37 129.2 0.0 1.8e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON98986.1 - 2.9e-24 84.7 0.0 6.1e-23 80.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EON98986.1 - 5.3e-06 26.3 0.1 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EON98986.1 - 0.0046 16.3 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ESR1_C PF12743.2 EON98986.1 - 0.091 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal TFIIA PF03153.8 EON98988.1 - 0.016 15.1 6.9 0.024 14.5 4.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EON98988.1 - 0.34 9.5 16.0 0.65 8.6 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EON98988.1 - 5.9 6.4 13.4 12 5.3 9.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin SUI1 PF01253.17 EON98989.1 - 2.3e-22 78.5 1.7 1.6e-21 75.8 1.2 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 EON98989.1 - 0.035 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) POX PF07526.6 EON98991.1 - 2.8 8.1 6.8 0.98 9.6 2.5 1.8 1 1 1 2 2 2 0 Associated with HOX DivIC PF04977.10 EON98991.1 - 5.9 6.4 7.2 3 7.4 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF1690 PF07956.6 EON98992.1 - 5.4e-36 123.6 9.5 6.4e-36 123.4 6.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Myosin_head PF00063.16 EON98992.1 - 0.0056 14.7 1.3 0.007 14.4 0.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Terminase_2 PF03592.11 EON98992.1 - 0.055 13.7 4.1 0.072 13.3 2.8 1.3 1 0 0 1 1 1 0 Terminase small subunit CAF-1_p150 PF11600.3 EON98992.1 - 0.12 11.7 13.3 0.16 11.3 9.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC PF04632.7 EON98992.1 - 0.31 9.4 2.0 0.36 9.1 1.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.6 EON98992.1 - 0.38 9.9 5.3 0.49 9.6 3.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase cwf21 PF08312.7 EON98992.1 - 1.3 8.8 8.0 9.3 6.2 4.6 2.5 1 1 1 2 2 2 0 cwf21 domain Phasin PF05597.6 EON98992.1 - 1.7 8.3 11.3 0.67 9.7 3.8 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Borrelia_P83 PF05262.6 EON98992.1 - 3.3 5.8 11.9 4.1 5.5 8.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FlxA PF14282.1 EON98992.1 - 6.2 6.8 12.5 17 5.3 2.0 2.0 1 1 1 2 2 2 0 FlxA-like protein Mnd1 PF03962.10 EON98992.1 - 7 6.2 10.9 13 5.4 7.6 1.5 1 1 0 1 1 1 0 Mnd1 family HEAT PF02985.17 EON98993.1 - 5.2e-14 51.0 13.5 0.016 15.2 0.0 10.5 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 EON98993.1 - 2.1e-13 50.3 15.3 0.00013 22.2 0.0 7.7 2 1 6 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EON98993.1 - 1.4e-10 41.3 13.2 2.9e-06 27.6 0.0 8.9 8 3 3 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EON98993.1 - 1.6e-07 31.1 7.5 7.8e-07 28.9 1.9 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 EON98993.1 - 2.5e-07 30.5 0.7 0.11 12.1 0.0 6.1 3 1 2 5 5 5 3 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EON98993.1 - 2.4e-05 23.8 3.0 3.8 6.8 0.0 5.5 3 1 2 6 6 6 3 CLASP N terminal DUF1548 PF07579.6 EON98993.1 - 0.1 12.6 3.9 2 8.5 0.0 4.0 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1548) ABC1 PF03109.11 EON98995.1 - 4.4e-24 84.7 0.0 1.3e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EON98995.1 - 0.027 14.1 0.1 0.13 11.9 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family PAPS_reduct PF01507.14 EON98996.1 - 1.9e-44 151.5 0.4 6.1e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DUF1270 PF06900.6 EON98996.1 - 0.18 12.0 0.1 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) PTCB-BRCT PF12738.2 EON98997.1 - 4.3e-12 45.6 0.0 8.7e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EON98997.1 - 4e-10 39.6 0.0 7.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EON98997.1 - 0.00024 21.1 0.0 0.00074 19.6 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain CENP-T PF15511.1 EON98997.1 - 0.0079 15.4 13.1 0.01 15.1 9.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T DUF3006 PF11213.3 EON98997.1 - 0.009 15.7 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) RR_TM4-6 PF06459.7 EON98997.1 - 2.2 8.0 10.2 3.3 7.5 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EON98997.1 - 3.3 7.0 14.9 5.2 6.3 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MORN PF02493.15 EON98998.1 - 0.15 11.8 0.1 14 5.5 0.0 2.2 2 0 0 2 2 2 0 MORN repeat Ferric_reduct PF01794.14 EON98999.1 - 2.5e-19 69.5 4.3 2.5e-19 69.5 3.0 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EON98999.1 - 6e-15 55.0 0.1 1.6e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EON98999.1 - 7.5e-14 51.9 0.0 5.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EON98999.1 - 0.00027 21.4 0.0 0.081 13.4 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EON98999.1 - 0.15 12.1 4.5 0.66 10.1 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) adh_short PF00106.20 EON99000.1 - 3.3e-08 33.6 0.0 5.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EON99000.1 - 4.3e-05 23.2 0.0 6.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DNA_methylase PF00145.12 EON99001.1 - 1.7e-07 30.6 2.0 4.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase UIM PF02809.15 EON99001.1 - 0.11 12.1 0.2 0.11 12.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Ribosomal_L13 PF00572.13 EON99001.1 - 0.12 12.4 0.3 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L13 TMEM171 PF15471.1 EON99002.1 - 0.35 9.5 0.5 0.53 9.0 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 BAF1_ABF1 PF04684.8 EON99002.1 - 0.42 9.3 5.3 0.41 9.4 0.0 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Amidohydro_1 PF01979.15 EON99003.1 - 4.4e-17 62.7 0.0 1.7e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EON99003.1 - 2.7e-14 53.8 0.1 4.9e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EON99003.1 - 3.9e-12 45.7 0.1 2e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EON99003.1 - 4.3e-05 22.9 0.2 0.0022 17.3 0.0 2.9 2 1 0 2 2 2 1 Amidohydrolase family Shisa PF13908.1 EON99004.1 - 0.0035 17.5 0.8 0.012 15.8 0.6 1.9 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 EON99004.1 - 0.0079 15.8 1.6 0.014 14.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) SKG6 PF08693.5 EON99004.1 - 0.01 15.1 1.1 0.01 15.1 0.7 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EON99004.1 - 0.016 13.4 0.1 0.025 12.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EON99004.1 - 0.025 13.2 1.6 0.037 12.6 1.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein PI3_PI4_kinase PF00454.22 EON99005.1 - 5.2e-51 173.3 0.0 8.4e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EON99005.1 - 8e-18 63.5 0.0 1.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 EON99005.1 - 1.9e-17 63.3 12.5 6.2e-14 51.7 8.6 3.1 1 1 0 1 1 1 1 FAT domain ALS2CR8 PF15299.1 EON99005.1 - 0.042 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Malate_synthase PF01274.17 EON99006.1 - 9.7e-235 779.5 0.0 1.1e-234 779.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase zf-PARP PF00645.13 EON99007.1 - 3.6e-13 49.5 0.4 5.3e-12 45.8 0.2 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF572 PF04502.8 EON99007.1 - 0.29 10.3 12.7 0.38 9.9 8.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) NAC PF01849.13 EON99009.1 - 1e-26 92.2 0.3 9.5e-26 89.0 0.1 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EON99009.1 - 4.1e-05 23.2 0.3 0.0001 22.0 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain SpoIIIAH PF12685.2 EON99009.1 - 0.66 9.4 8.8 0.14 11.6 1.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Glypican PF01153.14 EON99009.1 - 5 5.6 5.2 16 3.9 1.6 2.0 1 1 1 2 2 2 0 Glypican Fungal_trans PF04082.13 EON99010.1 - 3.6e-12 45.7 0.1 6e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Robl_LC7 PF03259.12 EON99011.1 - 8.8e-12 44.4 0.0 6.5e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Dioxygenase_C PF00775.16 EON99012.1 - 4.4e-53 179.2 0.0 6.4e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EON99012.1 - 4.1e-19 68.3 0.0 8e-18 64.1 0.0 2.7 3 0 0 3 3 3 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EON99012.1 - 5e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain GvpD PF07088.6 EON99012.1 - 0.038 12.3 0.0 0.086 11.1 0.0 1.5 2 0 0 2 2 2 0 GvpD gas vesicle protein DUF824 PF05688.6 EON99012.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) SEN1_N PF12726.2 EON99013.1 - 7.1e-82 275.6 0.0 9e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EON99013.1 - 5e-69 232.4 0.6 5e-69 232.4 0.4 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EON99013.1 - 1.4e-62 210.6 0.0 3e-62 209.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EON99013.1 - 7.1e-11 41.7 0.7 3.3e-10 39.5 0.5 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EON99013.1 - 1.2e-08 34.8 0.1 4.2e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EON99013.1 - 3.5e-07 30.0 0.2 0.012 15.1 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EON99013.1 - 2.4e-06 27.0 0.1 0.00088 18.6 0.1 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EON99013.1 - 0.006 16.0 0.1 0.018 14.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EON99013.1 - 0.02 14.6 0.1 0.12 12.2 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EON99013.1 - 0.054 13.1 0.2 4.2 6.9 0.0 2.8 2 1 1 3 3 3 0 Helicase AAA PF00004.24 EON99013.1 - 0.083 13.0 0.2 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EON99013.1 - 0.44 10.8 2.9 0.42 10.9 0.4 2.2 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EON99014.1 - 1.1e-92 304.5 12.0 5.9e-17 61.7 0.0 4.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EON99014.1 - 1.5e-45 150.7 18.1 2.1e-06 27.2 0.0 10.7 10 1 1 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 EON99014.1 - 1.8e-38 130.2 0.4 9.2e-08 32.3 0.0 8.2 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON99014.1 - 2.7e-31 106.8 9.0 3.5e-06 27.0 0.1 8.7 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON99014.1 - 7.7e-30 99.9 4.9 0.0094 16.1 0.0 10.5 11 0 0 11 11 11 6 Ankyrin repeat PPR_3 PF13812.1 EON99014.1 - 0.82 10.1 2.8 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Mt_ATP-synt_D PF05873.7 EON99017.1 - 1.3e-18 67.1 1.5 1.7e-18 66.7 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 EON99017.1 - 0.09 12.7 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain BLOC1_2 PF10046.4 EON99017.1 - 0.31 11.1 3.9 0.38 10.9 1.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 EON99017.1 - 0.32 8.4 1.2 0.36 8.3 0.8 1.0 1 0 0 1 1 1 0 Prominin IncA PF04156.9 EON99017.1 - 1.1 8.7 4.4 3 7.3 0.7 2.0 1 1 1 2 2 2 0 IncA protein PFK PF00365.15 EON99018.1 - 3e-164 544.8 3.2 8.4e-121 402.2 1.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase HMGL-like PF00682.14 EON99019.1 - 5.1e-66 222.7 0.0 1.9e-64 217.5 0.0 2.1 2 0 0 2 2 2 2 HMGL-like LeuA_dimer PF08502.5 EON99019.1 - 4e-22 78.4 0.0 9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain BetaGal_dom2 PF10435.4 EON99020.1 - 8.3e-60 201.2 0.4 1.5e-59 200.3 0.1 1.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EON99020.1 - 2.3e-48 163.0 3.4 1.6e-26 92.7 0.4 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.14 EON99020.1 - 7.6e-26 91.2 0.0 8.8e-23 81.1 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom3 PF13363.1 EON99020.1 - 1.2e-24 85.4 0.0 8.9e-24 82.6 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Aldedh PF00171.17 EON99021.1 - 4.5e-119 397.8 0.0 5.5e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pectinesterase PF01095.14 EON99022.1 - 1.4e-25 89.5 0.9 2e-20 72.5 0.8 2.1 2 0 0 2 2 2 2 Pectinesterase RRM_1 PF00076.17 EON99023.1 - 1.1e-19 69.8 0.0 3.7e-12 45.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99023.1 - 2.9e-12 46.3 0.1 1.2e-07 31.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99023.1 - 7.6e-07 28.8 0.0 0.00031 20.5 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 EON99024.1 - 3.1e-112 375.6 0.8 4.1e-112 375.1 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EON99024.1 - 9.6e-58 194.2 5.8 2e-57 193.2 4.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EON99024.1 - 6.3e-15 55.2 1.3 2.1e-05 24.6 0.0 6.0 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EON99024.1 - 0.0017 18.6 1.1 1.2 9.7 0.0 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EON99024.1 - 0.0023 17.3 3.9 0.028 13.7 0.1 3.2 3 0 0 3 3 3 1 CLASP N terminal Alpha_adaptin_C PF02296.11 EON99024.1 - 0.019 14.9 0.4 0.08 12.8 0.0 2.3 3 0 0 3 3 3 0 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 EON99024.1 - 0.26 11.4 8.7 2 8.7 0.2 4.8 5 0 0 5 5 5 0 HEAT repeat Ctr PF04145.10 EON99025.1 - 1.8e-29 102.6 0.4 2.1e-29 102.4 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Sugar_tr PF00083.19 EON99026.1 - 2.3e-28 98.9 13.4 2.6e-28 98.8 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99026.1 - 9e-12 44.3 7.8 9.8e-12 44.2 5.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EON99026.1 - 0.00092 17.7 6.0 0.00092 17.7 4.2 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EON99026.1 - 0.005 16.6 1.9 0.0052 16.5 0.1 2.0 2 0 0 2 2 2 1 MFS_1 like family MNSV_P7B PF06692.6 EON99026.1 - 0.15 11.8 1.0 0.9 9.3 0.2 2.3 1 1 1 2 2 2 0 Melon necrotic spot virus P7B protein TYW3 PF02676.9 EON99027.1 - 7.5e-34 116.6 0.0 1.1e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 CBM-like PF14683.1 EON99027.1 - 4.2e-30 104.5 0.0 9.1e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EON99027.1 - 1e-21 76.8 0.1 2.8e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EON99027.1 - 5.5e-06 26.3 0.2 2.9e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Abhydrolase_5 PF12695.2 EON99028.1 - 2.8e-07 30.3 0.1 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON99028.1 - 5.3e-05 23.2 3.3 8.8e-05 22.4 2.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EON99028.1 - 0.00015 21.3 0.1 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EON99028.1 - 0.017 14.6 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EON99028.1 - 0.027 14.6 0.1 0.097 12.8 0.0 1.9 2 1 0 2 2 2 0 Thioesterase domain Abhydrolase_4 PF08386.5 EON99028.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein SLS PF14611.1 EON99029.1 - 3.8e-37 127.7 0.4 5.7e-37 127.1 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GRAS PF03514.9 EON99029.1 - 0.04 12.6 0.1 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 GRAS domain family DUF1634 PF07843.6 EON99030.1 - 0.045 13.3 1.8 2.8 7.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) ATP-sulfurylase PF01747.12 EON99031.1 - 7.5e-88 293.4 0.0 1.1e-87 292.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EON99031.1 - 5.7e-58 195.0 0.1 8.7e-58 194.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EON99031.1 - 2e-52 176.8 0.0 3.4e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EON99031.1 - 0.015 15.2 0.1 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain LigB PF02900.13 EON99032.1 - 4.1e-53 180.1 0.6 4.7e-53 179.9 0.4 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ipi1_N PF12333.3 EON99033.1 - 1.1e-18 67.1 0.0 2.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Lyase_1 PF00206.15 EON99034.1 - 4.1e-110 367.8 0.0 6e-110 367.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EON99034.1 - 7e-22 77.2 0.0 1.6e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus AKNA PF12443.3 EON99034.1 - 0.059 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor ADH_zinc_N PF00107.21 EON99035.1 - 7e-06 25.6 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Gram_pos_anchor PF00746.16 EON99036.1 - 0.027 14.2 0.3 0.054 13.3 0.2 1.5 1 0 0 1 1 1 0 Gram positive anchor B12D PF06522.6 EON99036.1 - 0.1 12.3 1.3 0.43 10.3 0.0 2.4 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit HAD PF12710.2 EON99037.1 - 1.8e-21 77.1 0.0 2.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON99037.1 - 8.3e-12 45.9 2.9 2.1e-10 41.3 0.2 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON99037.1 - 8.7e-10 38.5 2.0 7.2e-09 35.5 0.1 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EON99037.1 - 2.7e-06 27.7 0.0 6.8e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EON99037.1 - 0.0015 17.5 0.1 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 EON99037.1 - 0.0032 16.6 0.0 0.88 8.6 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Acid_PPase PF12689.2 EON99037.1 - 0.12 11.9 0.0 0.45 10.1 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase p450 PF00067.17 EON99038.1 - 1.9e-44 151.9 0.0 2.6e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EON99039.1 - 2.3e-106 355.9 0.0 2.6e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EON99039.1 - 1.7e-06 27.4 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 EON99039.1 - 0.00054 18.8 0.0 0.0012 17.6 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Herpes_UL42 PF02282.11 EON99039.1 - 0.043 13.3 0.1 0.079 12.5 0.1 1.6 1 1 0 1 1 1 0 DNA polymerase processivity factor (UL42) EAF PF09816.4 EON99040.1 - 1.1e-17 63.9 0.1 2.8e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Senescence_reg PF04520.8 EON99040.1 - 0.0048 17.4 4.8 0.0048 17.4 3.3 2.4 2 1 1 3 3 3 1 Senescence regulator SR-25 PF10500.4 EON99040.1 - 0.012 15.0 9.1 0.012 15.0 6.3 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DEAD PF00270.24 EON99041.1 - 2.7e-43 147.3 0.0 6.2e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EON99041.1 - 5.5e-22 77.4 0.6 4.1e-21 74.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EON99041.1 - 0.08 12.2 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.10 EON99041.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit E1-E2_ATPase PF00122.15 EON99042.1 - 6.4e-15 54.8 0.0 3.1e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EON99042.1 - 2.6e-13 49.7 0.2 1.1e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EON99042.1 - 6e-12 46.1 0.0 1.9e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON99042.1 - 2.4e-10 41.2 5.2 3.4e-08 34.1 3.6 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON99042.1 - 0.005 16.4 0.6 0.018 14.6 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clenterotox PF03505.9 EON99042.1 - 0.071 12.4 0.3 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Clostridium enterotoxin BcrAD_BadFG PF01869.15 EON99043.1 - 0.0044 16.3 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family EI24 PF07264.6 EON99045.1 - 1.9e-05 24.2 11.1 4.7e-05 22.9 7.7 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) BAAT_C PF08840.6 EON99045.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FA_desaturase PF00487.19 EON99045.1 - 4.6 6.6 7.4 6.5 6.1 1.6 2.0 2 0 0 2 2 2 0 Fatty acid desaturase UPF0016 PF01169.14 EON99046.1 - 8.2e-41 138.0 27.8 4.5e-22 77.9 4.8 2.6 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Tetraspannin PF00335.15 EON99047.1 - 5.9e-07 28.9 5.6 8.9e-07 28.4 3.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Pyrid_oxidase_2 PF13883.1 EON99048.1 - 9.3e-44 149.1 0.0 1.8e-43 148.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Shal-type PF11601.3 EON99048.1 - 0.19 11.2 4.9 3.4 7.2 0.1 3.0 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels TPP_enzyme_M PF00205.17 EON99049.1 - 9.1e-20 70.8 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EON99049.1 - 7.1e-16 58.1 0.1 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EON99049.1 - 7.9e-12 44.9 0.0 2.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Phosphodiest PF01663.17 EON99050.1 - 1.7e-62 211.8 4.4 2.2e-40 139.1 0.1 2.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EON99050.1 - 0.016 14.4 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Sulfatase PglZ PF08665.7 EON99050.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 PglZ domain DUF229 PF02995.12 EON99050.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_28 PF00295.12 EON99052.1 - 2.4e-46 158.1 7.8 3.6e-46 157.6 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-CCCH PF00642.19 EON99053.1 - 0.0086 15.7 5.9 0.02 14.6 3.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BUD22 PF09073.5 EON99054.1 - 2.3 7.1 8.7 4.5 6.2 6.1 1.5 1 0 0 1 1 1 0 BUD22 WH1 PF00568.18 EON99055.1 - 8.1e-29 99.5 0.4 1.3e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 WH1 domain SF3b10 PF07189.6 EON99056.1 - 1.3e-41 140.2 0.0 1.5e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Abhydrolase_2 PF02230.11 EON99057.1 - 1.5e-59 201.0 0.0 1.8e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EON99057.1 - 1.5e-11 44.2 0.0 4.2e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON99057.1 - 4.1e-09 36.6 1.6 0.0012 18.8 1.3 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EON99057.1 - 7.6e-06 25.5 0.0 8.9e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EON99057.1 - 2.8e-05 23.8 0.0 0.026 14.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON99057.1 - 0.00027 20.2 0.6 0.012 14.8 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EON99057.1 - 0.0016 17.7 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EON99057.1 - 0.0053 16.3 0.1 0.79 9.2 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.17 EON99057.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 EON99057.1 - 0.076 12.3 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Glyco_hydro_76 PF03663.9 EON99058.1 - 6.1e-157 522.7 23.7 7.6e-157 522.4 16.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NYN PF01936.13 EON99059.1 - 2e-11 44.3 0.0 3.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain MaoC_dehydrat_N PF13452.1 EON99059.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase zf-CCHC PF00098.18 EON99059.1 - 0.26 11.3 6.6 0.44 10.5 1.4 3.4 3 1 0 3 3 3 0 Zinc knuckle Cyclin PF08613.6 EON99060.1 - 2.3e-13 50.8 1.0 7.8e-13 49.0 0.0 2.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EON99060.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SRF-TF PF00319.13 EON99063.1 - 8.4e-24 82.5 0.4 1.1e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EON99063.1 - 0.045 11.7 0.1 0.054 11.5 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.3 EON99063.1 - 0.084 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDP-OH_P_transf PF01066.16 EON99064.1 - 2.6e-15 56.5 3.4 2.6e-15 56.5 2.4 2.9 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.16 EON99065.1 - 1.5e-08 34.4 11.3 2.8e-08 33.5 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EON99065.1 - 8.3e-05 22.8 7.4 8.3e-05 22.8 5.2 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor Herpes_UL25 PF01499.11 EON99065.1 - 0.025 12.9 0.1 0.035 12.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family PAP1 PF08601.5 EON99065.1 - 0.11 12.2 4.9 0.53 9.9 3.4 2.3 1 1 0 1 1 1 0 Transcription factor PAP1 DUF972 PF06156.8 EON99065.1 - 0.11 12.7 0.8 0.29 11.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) LMSTEN PF07988.7 EON99065.1 - 0.17 11.1 0.7 11 5.3 0.0 2.5 2 1 0 2 2 2 0 LMSTEN motif ADIP PF11559.3 EON99065.1 - 0.43 10.4 12.5 0.038 13.9 5.5 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PAT1 PF09770.4 EON99065.1 - 1.2 7.2 20.0 1.5 6.9 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMCO5 PF14992.1 EON99065.1 - 2 7.4 5.0 3 6.9 3.5 1.2 1 0 0 1 1 1 0 TMCO5 family SNF2_N PF00176.18 EON99067.1 - 2.7e-71 239.8 0.0 4.4e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON99067.1 - 1.6e-13 50.3 0.0 3.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EON99067.1 - 3.9e-09 36.0 2.7 6.8e-09 35.2 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EON99067.1 - 1.1e-08 34.9 3.7 2.3e-08 33.9 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON99067.1 - 3.6e-08 32.9 3.8 8.1e-08 31.7 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EON99067.1 - 5.6e-08 32.4 3.6 1.1e-07 31.5 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EON99067.1 - 9.6e-07 28.5 3.8 2.9e-06 27.0 2.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EON99067.1 - 4.6e-06 26.2 3.1 4.6e-06 26.2 2.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EON99067.1 - 3.4e-05 23.4 0.8 8.1e-05 22.2 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.24 EON99067.1 - 0.00035 20.0 0.0 0.0011 18.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-MIZ PF02891.15 EON99067.1 - 0.022 14.2 1.2 0.051 13.0 0.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EON99067.1 - 0.051 13.1 4.9 0.29 10.7 3.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EON99067.1 - 0.075 12.7 2.7 0.071 12.8 0.3 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Nop14 PF04147.7 EON99067.1 - 0.3 8.9 21.2 0.44 8.3 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EON99067.1 - 0.47 9.4 21.4 0.79 8.7 14.8 1.4 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 EON99067.1 - 2.8 6.5 25.1 4.6 5.8 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3347 PF11827.3 EON99067.1 - 3.3 7.6 8.8 7.3 6.5 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Myb_DNA-bind_6 PF13921.1 EON99068.1 - 0.007 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EON99068.1 - 0.011 15.7 0.4 0.027 14.5 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1438 PF07270.6 EON99068.1 - 0.047 13.5 1.8 0.22 11.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Ferric_reduct PF01794.14 EON99070.1 - 8.3e-21 74.3 10.7 8.3e-21 74.3 7.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EON99070.1 - 2.1e-18 66.7 0.0 3.7e-16 59.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EON99070.1 - 1.2e-10 41.2 0.0 4e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain DUF4293 PF14126.1 EON99071.1 - 1.7 8.5 9.1 0.71 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Septin PF00735.13 EON99072.1 - 7.8e-31 107.1 0.0 1.5e-11 43.8 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.1 EON99072.1 - 0.014 15.6 0.1 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EON99072.1 - 0.019 14.9 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EON99072.1 - 0.056 13.9 0.1 0.23 11.9 0.0 2.1 3 1 0 3 3 3 0 Miro-like protein Dynamin_N PF00350.18 EON99072.1 - 0.082 12.7 0.0 0.85 9.4 0.0 2.4 3 0 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.13 EON99072.1 - 0.087 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3313 PF11769.3 EON99072.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) AAA_14 PF13173.1 EON99072.1 - 0.12 12.2 0.0 0.58 10.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EON99073.1 - 3.4e-71 239.4 0.0 5.2e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99073.1 - 6.3e-37 127.0 0.2 1.1e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EON99073.1 - 8.1e-07 28.2 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON99073.1 - 0.0002 21.2 0.2 0.00084 19.1 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EON99073.1 - 0.0038 16.8 0.8 0.0079 15.7 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EON99073.1 - 0.013 14.8 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SSF PF00474.12 EON99074.1 - 1e-09 37.5 28.2 1.3e-08 33.9 19.4 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family IMD PF08397.6 EON99075.1 - 0.003 16.8 3.7 0.2 10.9 0.8 2.2 2 0 0 2 2 2 2 IRSp53/MIM homology domain EOS1 PF12326.3 EON99076.1 - 1.1e-26 93.2 13.1 1.8e-23 82.7 5.0 2.2 1 1 1 2 2 2 2 N-glycosylation protein Nodulin-like PF06813.8 EON99076.1 - 0.028 13.6 2.4 0.14 11.3 0.8 2.1 1 1 1 2 2 2 0 Nodulin-like ADH_zinc_N PF00107.21 EON99078.1 - 3.8e-09 36.1 1.4 6.8e-09 35.3 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON99078.1 - 1.7e-07 30.9 0.0 3.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain vATP-synt_E PF01991.13 EON99080.1 - 7.6e-66 221.1 14.5 8.8e-66 220.9 10.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit AAA_15 PF13175.1 EON99080.1 - 0.054 12.5 3.9 0.069 12.1 2.7 1.1 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_7 PF03492.10 EON99080.1 - 0.094 11.4 2.9 0.25 10.0 2.0 1.6 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Gluconate_2-dh3 PF13618.1 EON99080.1 - 0.99 9.5 5.1 5.3 7.2 3.2 2.2 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Transposase_24 PF03004.9 EON99080.1 - 1 9.2 7.6 0.86 9.4 0.1 2.7 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) Mid2 PF04478.7 EON99081.1 - 1.8e-06 27.4 4.1 1.8e-06 27.4 2.8 2.5 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EON99081.1 - 0.0075 15.5 0.5 0.031 13.6 0.3 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Presenilin PF01080.12 EON99081.1 - 2.2 6.9 9.6 3 6.5 6.6 1.2 1 0 0 1 1 1 0 Presenilin DUF566 PF04484.7 EON99081.1 - 3.9 6.9 14.5 5.1 6.5 10.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) CytochromB561_N PF09786.4 EON99081.1 - 4.6 5.5 14.5 6.1 5.1 10.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal CorA PF01544.13 EON99082.1 - 3e-13 49.4 0.1 5.2e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_tranf_2_5 PF13712.1 EON99082.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family Sipho_Gp157 PF05565.6 EON99082.1 - 0.35 10.4 3.5 3.2 7.3 0.2 2.2 1 1 0 2 2 2 0 Siphovirus Gp157 CENP-O PF09496.5 EON99083.1 - 4.9e-25 87.5 0.1 1.4e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Uds1 PF15456.1 EON99083.1 - 0.27 11.2 4.0 1.7 8.6 1.4 2.4 3 0 0 3 3 3 0 Up-regulated During Septation p450 PF00067.17 EON99084.1 - 7.6e-49 166.4 0.0 9.7e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EON99084.1 - 0.1 11.0 0.2 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Daxx Family SMC_N PF02463.14 EON99085.1 - 3e-26 92.0 0.0 7.7e-26 90.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EON99085.1 - 5.3e-16 59.5 0.0 5.3e-16 59.5 0.0 4.8 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EON99085.1 - 4.9e-07 29.9 0.1 0.00088 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EON99085.1 - 0.0095 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EON99085.1 - 0.025 14.7 1.1 0.52 10.5 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EON99085.1 - 0.05 13.7 3.2 2.3 8.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain MtrB PF05440.7 EON99085.1 - 0.22 11.5 0.6 0.99 9.4 0.2 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_17 PF13207.1 EON99085.1 - 1.2 9.9 0.0 1.2 9.9 0.0 3.9 3 2 0 3 3 3 0 AAA domain DUF948 PF06103.6 EON99085.1 - 5.8 6.8 26.2 0.56 10.1 3.6 4.9 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EON99085.1 - 7.5 5.6 12.1 0.63 9.1 0.7 3.2 3 1 0 3 3 3 0 Reovirus sigma C capsid protein PAM2 PF07145.10 EON99086.1 - 0.00049 19.4 10.8 0.21 11.1 1.0 4.4 4 0 0 4 4 4 3 Ataxin-2 C-terminal region DUF3325 PF11804.3 EON99087.1 - 0.096 12.6 6.6 0.14 12.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Ribosomal_L14e PF01929.12 EON99088.1 - 2.2e-29 101.5 5.1 3.2e-29 101.0 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EON99088.1 - 0.0061 16.2 0.0 0.025 14.2 0.0 2.0 2 0 0 2 2 2 1 KOW motif SUR7 PF06687.7 EON99089.1 - 2.3e-29 102.4 12.7 2.9e-29 102.1 8.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EON99089.1 - 0.0043 17.2 2.6 0.0043 17.2 1.8 2.6 2 1 1 3 3 3 1 NfeD-like C-terminal, partner-binding 7TM_GPCR_Srd PF10317.4 EON99089.1 - 0.068 12.1 8.0 0.13 11.2 5.6 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd MARVEL PF01284.18 EON99089.1 - 0.45 10.3 8.3 2 8.2 5.7 2.0 1 1 0 1 1 1 0 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EON99089.1 - 0.87 9.2 19.6 0.2 11.3 8.3 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4231 PF14015.1 EON99089.1 - 5.6 7.0 6.3 1 9.3 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3165 PF11364.3 EON99089.1 - 6.5 6.9 14.2 0.79 9.8 3.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3165) Polysacc_deac_1 PF01522.16 EON99091.1 - 1.3e-08 34.4 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase VIGSSK PF14773.1 EON99092.1 - 1.3e-11 44.1 2.3 5.4 6.9 0.0 7.6 1 1 7 8 8 8 6 Helicase-associated putative binding domain, C-terminal PPO1_DWL PF12142.3 EON99092.1 - 0.00019 20.8 0.9 31 4.1 0.0 5.1 1 1 5 6 6 6 0 Polyphenol oxidase middle domain HTHP PF11534.3 EON99092.1 - 0.016 15.2 3.4 18 5.5 0.0 4.0 1 1 4 6 6 6 0 Hexameric tyrosine-coordinated heme protein (HTHP) Orthopox_B11R PF07033.6 EON99092.1 - 0.067 12.6 0.5 6.7 6.2 0.0 3.3 1 1 1 3 3 3 0 Orthopoxvirus B11R protein zf-CCHH PF10283.4 EON99092.1 - 0.19 11.6 22.2 86 3.0 0.0 7.8 8 0 0 8 8 8 0 Zinc-finger (CX5CX6HX5H) motif DUF533 PF04391.7 EON99093.1 - 0.022 14.1 0.7 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF533) MRP-S26 PF14943.1 EON99093.1 - 1.4 8.4 9.7 0.21 11.1 0.4 2.7 2 2 0 2 2 2 0 Mitochondrial ribosome subunit S26 Acatn PF13000.2 EON99094.1 - 3.7e-151 504.3 21.3 2.1e-77 260.9 5.6 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3951 PF13131.1 EON99094.1 - 0.0085 15.8 0.8 0.052 13.3 0.5 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3951) ERCC4 PF02732.10 EON99095.1 - 5.5e-25 87.7 0.0 1.4e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Tim44 PF04280.10 EON99097.1 - 2.9e-07 30.5 0.0 5.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 EON99097.1 - 0.00032 19.6 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein NmrA PF05368.8 EON99098.1 - 1.1e-14 54.2 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON99098.1 - 7.1e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding GTP_EFTU PF00009.22 EON99099.1 - 2e-21 76.3 0.0 3.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EON99099.1 - 1.5e-12 47.5 0.1 4.3e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EON99099.1 - 2.5e-10 40.3 1.5 2.3e-09 37.2 0.5 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EON99099.1 - 0.00063 19.2 0.5 0.11 11.9 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EON99099.1 - 0.0029 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EON99099.1 - 0.0043 17.5 0.1 0.049 14.1 0.1 2.6 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EON99099.1 - 0.017 14.7 0.0 0.062 12.9 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF258 PF03193.11 EON99099.1 - 0.02 14.0 0.1 0.05 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EON99099.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Dynamin family Av_adeno_fibre PF06536.6 EON99100.1 - 0.017 14.8 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Avian adenovirus fibre S1 PF00575.18 EON99101.1 - 6.3e-83 272.8 57.2 1e-15 57.5 0.8 13.5 14 1 0 15 15 15 10 S1 RNA binding domain NRDE-2 PF08424.5 EON99101.1 - 0.0016 17.3 0.8 0.032 13.1 0.2 2.4 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference S1_2 PF13509.1 EON99101.1 - 0.0017 18.2 1.1 17 5.4 0.0 5.3 6 0 0 6 6 6 0 S1 domain TPR_14 PF13428.1 EON99101.1 - 0.002 18.6 2.6 2.7 8.8 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EON99101.1 - 0.004 16.9 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Suf PF05843.9 EON99101.1 - 0.006 16.3 6.1 0.71 9.5 0.2 3.7 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EON99101.1 - 0.03 14.6 0.0 13 6.2 0.0 3.9 3 1 1 5 5 5 0 Tetratricopeptide repeat MRP-S35 PF10246.4 EON99101.1 - 0.038 13.9 0.4 2.7 7.9 0.0 3.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Pox_RNA_pol PF03293.9 EON99101.1 - 0.09 12.2 0.9 11 5.4 0.0 3.8 4 0 0 4 4 4 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Methyltransf_11 PF08241.7 EON99102.1 - 3.5e-21 75.4 0.0 6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99102.1 - 4.6e-20 71.7 0.0 6.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99102.1 - 9.9e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON99102.1 - 6.1e-16 58.5 0.0 9.2e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99102.1 - 4.1e-14 52.7 0.0 6.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99102.1 - 1.6e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON99102.1 - 2.2e-11 43.8 0.2 4.1e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON99102.1 - 5.9e-11 41.9 0.0 2.6e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EON99102.1 - 9.1e-08 31.1 0.0 1.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EON99102.1 - 2.2e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EON99102.1 - 0.0034 16.5 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EON99102.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase SQS_PSY PF00494.14 EON99102.1 - 0.043 13.0 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase PrmA PF06325.8 EON99102.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EON99102.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ribosomal_L34e PF01199.13 EON99105.1 - 3.8e-37 126.4 2.9 5e-37 126.0 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EON99105.1 - 4.5 6.9 6.6 10 5.8 0.1 2.9 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain ATG16 PF08614.6 EON99106.1 - 1.6e-48 165.1 17.2 1.8e-48 164.9 11.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EON99106.1 - 0.0039 15.8 9.1 0.0061 15.2 6.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IKKbetaNEMObind PF12179.3 EON99106.1 - 0.035 13.9 0.2 0.25 11.2 0.2 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Atg14 PF10186.4 EON99106.1 - 0.1 11.5 12.0 0.16 10.9 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EON99106.1 - 0.14 11.9 17.1 0.24 11.2 8.7 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EON99106.1 - 0.19 9.5 4.9 0.23 9.2 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 EON99106.1 - 0.28 11.1 7.1 0.2 11.6 4.1 1.4 2 0 0 2 2 2 0 Zinc finger-containing protein SecD-TM1 PF13721.1 EON99106.1 - 0.38 11.0 3.4 0.37 11.0 0.4 2.2 1 1 1 2 2 2 0 SecD export protein N-terminal TM region DUF4201 PF13870.1 EON99106.1 - 0.5 9.7 15.3 0.34 10.3 6.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.1 EON99106.1 - 0.71 9.0 17.5 1.6 7.9 3.7 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 EON99106.1 - 2.9 8.4 17.4 4 7.9 0.1 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EON99106.1 - 3 6.7 13.6 0.99 8.3 7.6 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Synaphin PF05835.7 EON99106.1 - 6.3 6.9 16.2 1.7 8.8 5.9 2.9 1 1 1 2 2 2 0 Synaphin protein Spc24 PF08286.6 EON99106.1 - 9.8 5.9 10.7 21 4.8 4.7 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 LDB19 PF13002.2 EON99107.1 - 4.5e-34 117.6 0.1 8.2e-34 116.7 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EON99107.1 - 0.00031 20.5 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L18e PF00828.14 EON99108.1 - 1.8e-19 70.3 0.4 3e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PROCN PF08083.6 EON99109.1 - 1.9e-220 731.4 10.0 1.9e-220 731.4 6.9 1.5 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EON99109.1 - 2.3e-125 416.5 1.9 4.2e-125 415.6 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EON99109.1 - 1.6e-94 313.6 1.1 4.1e-94 312.2 0.8 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EON99109.1 - 1.1e-76 255.6 4.4 1.2e-76 255.4 1.6 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EON99109.1 - 4.2e-67 223.9 0.1 9.3e-67 222.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EON99109.1 - 9.4e-44 147.2 0.1 2.5e-43 145.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EON99109.1 - 5.9e-43 145.5 0.2 1.6e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF3753 PF12575.3 EON99109.1 - 0.09 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) PX PF00787.19 EON99111.1 - 9.2e-18 64.0 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Asp PF00026.18 EON99112.1 - 3.2e-60 204.0 0.1 3.8e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON99112.1 - 1.1e-09 38.4 0.0 8.9e-08 32.2 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EON99112.1 - 0.002 18.5 0.1 0.18 12.3 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease Fungal_trans PF04082.13 EON99114.1 - 0.00081 18.3 0.0 0.0014 17.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_30 PF02055.11 EON99115.1 - 3.8e-15 55.0 0.6 1.2e-08 33.6 0.3 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EON99115.1 - 2e-12 46.7 0.1 5e-12 45.4 0.1 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF1966 PF09260.6 EON99115.1 - 0.071 13.1 0.8 0.41 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) eIF3_subunit PF08597.5 EON99116.1 - 0.0029 17.1 6.2 0.0029 17.1 4.3 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Nucleoplasmin PF03066.10 EON99116.1 - 0.092 12.2 10.4 0.044 13.2 2.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4484 PF14831.1 EON99116.1 - 0.22 11.6 5.2 0.41 10.7 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Spt5_N PF11942.3 EON99116.1 - 0.57 10.8 13.9 0.25 12.0 2.1 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SAPS PF04499.10 EON99116.1 - 0.83 8.2 5.8 1.2 7.6 4.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-B_dimeris PF09026.5 EON99116.1 - 4 7.7 11.6 1.2 9.4 4.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain YL1 PF05764.8 EON99116.1 - 5.3 6.5 19.0 4 6.9 5.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF3140 PF11338.3 EON99117.1 - 3.2e-32 110.5 1.5 3.2e-32 110.5 1.0 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF3140) DUF2945 PF11160.3 EON99117.1 - 0.0048 16.6 1.5 0.0048 16.6 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2945) AA_permease PF00324.16 EON99118.1 - 6.5e-89 298.4 36.8 8.5e-89 298.0 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON99118.1 - 5.2e-23 81.2 40.0 8.5e-23 80.5 27.7 1.3 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S19e PF01090.14 EON99119.1 - 2.1e-57 192.4 0.2 2.4e-57 192.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 EON99119.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Ribosomal_S6 PF01250.12 EON99120.1 - 6.9e-11 41.8 0.0 8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 adh_short PF00106.20 EON99121.1 - 1.5e-09 37.9 3.3 1.7e-09 37.8 2.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99121.1 - 1.2e-07 31.7 0.3 1.4e-07 31.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99121.1 - 9.5e-07 28.6 1.1 1.1e-06 28.3 0.8 1.0 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EON99121.1 - 0.00023 20.8 0.3 0.00026 20.6 0.2 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EON99121.1 - 0.0047 16.5 1.5 0.0054 16.3 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EON99121.1 - 0.022 13.8 0.7 0.24 10.4 0.3 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EON99121.1 - 0.094 12.5 2.4 0.32 10.8 1.6 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain EII-Sor PF03609.9 EON99121.1 - 0.098 11.9 0.9 0.11 11.8 0.6 1.1 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Cullin_binding PF03556.10 EON99122.1 - 1.8e-31 108.7 2.3 2.5e-31 108.2 1.6 1.2 1 0 0 1 1 1 1 Cullin binding Chs3p PF12271.3 EON99123.1 - 2.8e-140 466.4 12.4 3.1e-140 466.2 8.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 EON99123.1 - 0.35 10.7 7.7 0.036 13.9 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) PA14_2 PF10528.4 EON99124.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 GLEYA domain FHA PF00498.21 EON99125.1 - 1.2e-15 57.3 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EON99125.1 - 3e-06 26.9 12.3 4.7e-06 26.3 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EON99125.1 - 9.4e-05 22.4 6.2 0.00017 21.6 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EON99125.1 - 0.019 14.6 13.0 0.031 13.9 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EON99125.1 - 0.021 14.6 2.2 0.035 13.9 1.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EON99125.1 - 0.093 12.4 7.6 0.17 11.6 5.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EON99125.1 - 0.3 10.8 10.0 0.49 10.1 6.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EON99125.1 - 0.91 9.6 14.4 1.5 8.9 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EON99125.1 - 2.1 8.4 8.6 3.5 7.6 5.9 1.4 1 0 0 1 1 1 0 RING-like domain PIG-L PF02585.12 EON99126.1 - 7.1e-26 91.2 0.0 1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SNF2_N PF00176.18 EON99127.1 - 1.2e-71 240.9 0.0 1.7e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EON99127.1 - 7.2e-22 77.3 0.0 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EON99127.1 - 1.5e-13 50.3 0.0 3.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EON99127.1 - 1.3e-05 25.0 13.1 2.7e-05 24.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EON99127.1 - 0.00029 20.4 13.9 0.00058 19.4 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EON99127.1 - 0.0023 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EON99127.1 - 0.0034 17.0 10.6 0.0063 16.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EON99127.1 - 0.0063 16.3 13.1 0.013 15.3 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain PLU-1 PF08429.6 EON99127.1 - 0.046 12.6 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 PLU-1-like protein zf-RING_5 PF14634.1 EON99127.1 - 0.87 9.3 11.9 3.3 7.5 8.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Dehydratase_hem PF13816.1 EON99128.1 - 9.4e-80 267.9 0.0 1.1e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EON99128.1 - 0.05 13.6 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) Amidoligase_2 PF12224.3 EON99129.1 - 1.3e-21 77.3 0.1 5.1e-20 72.1 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme Methyltransf_11 PF08241.7 EON99130.1 - 2e-19 69.8 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99130.1 - 2.3e-15 56.4 0.0 3.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99130.1 - 7.8e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON99130.1 - 1.9e-11 43.9 0.0 2.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON99130.1 - 2.6e-10 39.8 0.0 3.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EON99130.1 - 2.2e-09 37.6 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EON99130.1 - 9.1e-08 31.4 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EON99130.1 - 6.8e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON99130.1 - 3.1e-06 27.2 0.0 7.3e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EON99130.1 - 6.6e-05 22.6 0.0 0.00085 19.0 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 EON99130.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EON99130.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EON99130.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EON99130.1 - 0.0083 15.1 0.0 0.15 11.0 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase PCMT PF01135.14 EON99130.1 - 0.0091 15.5 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EON99130.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EON99130.1 - 0.027 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TehB PF03848.9 EON99130.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EON99130.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EON99130.1 - 0.074 12.0 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Peptidase_M16_C PF05193.16 EON99131.1 - 1.7e-52 177.7 0.0 1e-51 175.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EON99131.1 - 1.7e-41 141.4 0.0 5.8e-41 139.7 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Hemerythrin PF01814.18 EON99132.1 - 2.6e-13 50.2 1.3 3.8e-13 49.7 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DOT1 PF08123.8 EON99133.1 - 5.2e-73 244.7 0.0 6.8e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EON99133.1 - 0.00029 20.8 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99133.1 - 0.0045 17.5 0.1 0.015 15.9 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON99133.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_6 PF12697.2 EON99134.1 - 1.8e-25 90.1 0.5 3.5e-25 89.2 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON99134.1 - 4.7e-15 55.6 0.0 2.1e-14 53.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON99134.1 - 1.3e-10 41.2 0.0 1.1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 EON99134.1 - 5.6e-10 38.9 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EON99134.1 - 7e-06 26.1 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.15 EON99134.1 - 2.9e-05 24.4 0.1 7.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EON99134.1 - 0.00053 19.6 0.0 0.0028 17.2 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 EON99134.1 - 0.0072 15.7 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Y_phosphatase PF00102.22 EON99134.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ser_hydrolase PF06821.8 EON99134.1 - 0.02 14.4 0.0 0.097 12.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.2 EON99134.1 - 0.046 12.5 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EON99134.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EON99134.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF2305 PF10230.4 EON99134.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EON99134.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EON99134.1 - 0.17 11.1 0.0 0.48 9.6 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Rab5ip PF07019.7 EON99135.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF3953 PF13129.1 EON99135.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) FAD_binding_3 PF01494.14 EON99136.1 - 1.9e-19 69.9 0.0 2.6e-18 66.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON99136.1 - 2.2e-09 36.6 4.1 0.00058 18.8 1.2 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON99136.1 - 3.2e-06 27.0 0.5 1.8e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EON99136.1 - 1.3e-05 24.3 0.3 3e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EON99136.1 - 4.2e-05 23.8 0.1 0.0091 16.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99136.1 - 0.00011 22.3 0.1 0.00032 20.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON99136.1 - 0.00031 20.7 0.7 0.0013 18.6 0.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EON99136.1 - 0.00035 19.6 0.0 0.00098 18.1 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EON99136.1 - 0.00093 17.7 0.4 0.22 9.9 0.5 2.0 2 0 0 2 2 2 2 HI0933-like protein 120_Rick_ant PF12574.3 EON99136.1 - 0.026 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Rossmann-like PF10727.4 EON99136.1 - 0.041 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Amino_oxidase PF01593.19 EON99136.1 - 0.056 12.5 0.1 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EON99136.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EON99136.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.17 EON99137.1 - 3.8e-152 506.8 0.8 4.3e-152 506.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EON99137.1 - 0.0011 18.2 0.0 0.0053 16.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Glyco_hydro_28 PF00295.12 EON99138.1 - 1.2e-28 100.0 10.3 1.8e-28 99.4 7.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2469 PF10611.4 EON99138.1 - 0.13 12.5 0.2 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) ADH_zinc_N PF00107.21 EON99139.1 - 6.8e-08 32.1 0.0 9.9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EON99139.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF4235 PF14019.1 EON99139.1 - 0.094 12.5 0.1 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) SnoaL_4 PF13577.1 EON99140.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3722 PF12519.3 EON99141.1 - 1.9e-80 269.8 0.0 3.8e-80 268.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EON99141.1 - 0.0014 18.0 0.1 0.025 13.8 0.1 2.4 3 0 0 3 3 3 1 Eukaryotic porin adh_short PF00106.20 EON99142.1 - 2.9e-16 59.8 1.0 5e-16 59.0 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99142.1 - 4.8e-11 42.6 0.5 9e-11 41.7 0.4 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EON99142.1 - 0.088 12.9 1.0 0.26 11.3 0.3 1.9 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2796 PF10986.3 EON99144.1 - 0.051 13.5 0.7 0.084 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF4611 PF15387.1 EON99144.1 - 0.077 13.1 2.4 0.11 12.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 EON99144.1 - 0.13 11.9 4.6 0.38 10.4 0.3 2.2 2 0 0 2 2 2 0 FAM176 family NPDC1 PF06809.6 EON99144.1 - 0.13 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Red1 PF07964.6 EON99144.1 - 0.19 9.8 2.8 0.25 9.4 2.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Sporozoite_P67 PF05642.6 EON99144.1 - 0.23 9.2 1.5 0.28 8.9 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Bd3614_N PF14442.1 EON99144.1 - 0.89 9.5 5.1 1.4 8.8 3.6 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal FLO_LFY PF01698.11 EON99144.1 - 9.2 4.9 6.5 13 4.5 4.3 1.4 1 1 1 2 2 2 0 Floricaula / Leafy protein Scytalone_dh PF02982.9 EON99145.1 - 6.1e-91 302.1 1.9 7e-91 301.9 1.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EON99145.1 - 9.1e-07 28.8 0.6 1.3e-06 28.3 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain FAR1 PF03101.10 EON99146.1 - 0.0005 20.5 0.1 0.00092 19.6 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain HSBP1 PF06825.7 EON99146.1 - 0.0046 16.4 2.4 0.14 11.7 0.1 2.6 2 0 0 2 2 2 1 Heat shock factor binding protein 1 AFT PF08731.6 EON99146.1 - 0.013 15.6 0.4 0.029 14.5 0.3 1.7 1 1 0 1 1 1 0 Transcription factor AFT XhlA PF10779.4 EON99146.1 - 0.039 13.8 0.3 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF2802 PF10975.3 EON99146.1 - 0.049 13.3 0.7 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Snapin_Pallidin PF14712.1 EON99146.1 - 0.056 13.7 0.1 4.8 7.5 0.1 2.5 3 0 0 3 3 3 0 Snapin/Pallidin PilJ PF13675.1 EON99146.1 - 0.076 13.3 0.2 0.17 12.2 0.2 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Zip PF02535.17 EON99148.1 - 6.8e-56 189.5 7.6 1.1e-55 188.9 5.2 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter MAP65_ASE1 PF03999.7 EON99149.1 - 4.7e-74 250.1 1.9 9.5e-74 249.1 1.2 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) NUDIX PF00293.23 EON99150.1 - 9.1e-18 64.1 0.1 1.4e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EON99150.1 - 0.00089 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain eIF-3c_N PF05470.7 EON99151.1 - 5e-176 586.3 23.8 1.5e-141 472.5 2.4 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EON99151.1 - 1e-13 51.4 0.1 4.7e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain Mem_trans PF03547.13 EON99151.1 - 0.1 10.8 0.4 0.11 10.7 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein ATP13 PF12921.2 EON99152.1 - 1.8e-22 78.9 0.0 4.3e-22 77.8 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATPase expression PTCB-BRCT PF12738.2 EON99155.1 - 1.8e-46 155.8 0.4 6.4e-21 73.9 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EON99155.1 - 6.3e-38 128.7 0.3 2.7e-12 46.6 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PipA PF07108.6 EON99155.1 - 0.095 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PipA protein CN_hydrolase PF00795.17 EON99156.1 - 2.6e-22 79.0 0.0 2.9e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FA_desaturase PF00487.19 EON99157.1 - 1.1e-38 133.1 22.5 1.6e-38 132.6 15.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EON99157.1 - 3.8e-06 26.6 0.0 9.2e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3716 PF12511.3 EON99158.1 - 8.5e-10 38.0 7.6 1.5e-09 37.3 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) cwf21 PF08312.7 EON99158.1 - 0.015 15.1 2.5 2.5 8.0 0.0 2.9 2 1 0 2 2 2 0 cwf21 domain Glyco_hydro_28 PF00295.12 EON99159.1 - 1.1e-27 96.8 2.0 1.6e-27 96.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EON99159.1 - 0.23 11.2 15.7 0.86 9.3 10.9 2.0 1 1 0 1 1 1 0 Right handed beta helix region Vps16_N PF04841.8 EON99160.1 - 1.5e-85 287.2 0.0 1.5e-55 188.3 0.0 2.1 1 1 1 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.7 EON99160.1 - 9.2e-73 244.9 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region WD40 PF00400.27 EON99160.1 - 0.041 13.7 0.1 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_S10 PF00450.17 EON99161.1 - 5.7e-82 276.0 0.5 1.5e-81 274.6 0.3 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Urb2 PF10441.4 EON99162.1 - 3.4e-63 213.2 0.6 6.2e-63 212.3 0.4 1.4 1 0 0 1 1 1 1 Urb2/Npa2 family Polyketide_cyc PF03364.15 EON99163.1 - 6.3e-22 77.9 0.0 8.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport D123 PF07065.9 EON99164.1 - 3.2e-74 249.7 0.0 5.2e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 D123 GDA1_CD39 PF01150.12 EON99165.1 - 3.4e-96 322.4 0.0 4e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Sas10 PF09368.5 EON99166.1 - 1.8e-29 101.7 6.2 1.8e-29 101.7 4.3 2.7 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EON99166.1 - 7.4e-13 48.5 0.0 2.1e-11 43.8 0.0 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family IF4E PF01652.13 EON99167.1 - 3.4e-38 130.7 0.3 4.3e-38 130.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CN_hydrolase PF00795.17 EON99168.1 - 1.4e-24 86.5 0.0 2.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EON99168.1 - 7.4e-22 77.4 0.0 4.4e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Vps51 PF08700.6 EON99169.1 - 1.4e-11 44.0 0.0 5.3e-11 42.1 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 TGT PF01702.13 EON99170.1 - 2.5e-30 105.5 0.0 3.9e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-C2H2_4 PF13894.1 EON99171.1 - 0.0041 17.3 12.0 0.022 15.0 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EON99171.1 - 0.016 15.5 3.5 1.5 9.2 0.0 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Kinesin PF00225.18 EON99172.1 - 3.5e-113 377.7 0.0 3.5e-113 377.7 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain DUF87 PF01935.12 EON99172.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 DUF2018 PF09442.5 EON99172.1 - 0.69 10.5 3.3 0.92 10.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF972 PF06156.8 EON99172.1 - 6.9 7.0 11.2 6.9 7.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TRAPP PF04051.11 EON99173.1 - 8.5e-38 129.2 0.0 1.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component G-alpha PF00503.15 EON99174.1 - 3.8e-134 447.2 2.3 4.6e-134 446.9 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EON99174.1 - 2e-15 56.5 1.4 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EON99174.1 - 9.4e-05 21.9 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EON99174.1 - 0.0015 18.9 0.6 2.7 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EON99174.1 - 0.0056 15.8 2.9 0.27 10.3 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EON99174.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EON99174.1 - 0.03 13.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EON99174.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 EON99174.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EON99174.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.17 EON99175.1 - 5.8e-57 191.6 0.1 6.8e-57 191.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EON99175.1 - 3e-18 66.4 0.0 4.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON99175.1 - 1.6e-13 50.2 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EON99175.1 - 5.6e-08 32.7 0.0 7.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EON99175.1 - 1.1e-07 31.2 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EON99175.1 - 1.1e-06 28.2 0.0 2.1e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EON99175.1 - 0.00071 19.7 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EON99175.1 - 0.00095 18.3 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EON99175.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EON99175.1 - 0.0016 17.6 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EON99175.1 - 0.0038 17.2 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EON99175.1 - 0.0042 16.6 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EON99175.1 - 0.0045 16.7 0.1 0.0095 15.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase ATP_bind_1 PF03029.12 EON99175.1 - 0.0048 16.4 0.3 0.17 11.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EON99175.1 - 0.0067 15.9 0.2 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 EON99175.1 - 0.0069 15.8 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EON99175.1 - 0.014 14.4 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 EON99175.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EON99175.1 - 0.023 14.3 0.1 0.056 13.1 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EON99175.1 - 0.039 13.3 0.0 0.12 11.8 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EON99175.1 - 0.056 13.6 0.1 0.27 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 EON99175.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EON99175.1 - 0.091 12.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.17 EON99175.1 - 0.091 11.5 0.3 0.46 9.2 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Methyltransf_12 PF08242.7 EON99176.1 - 6.2e-14 52.2 0.0 1.8e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON99176.1 - 4e-10 40.0 0.0 7.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99176.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON99176.1 - 5.2e-09 36.0 0.1 9.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99176.1 - 2.7e-08 34.3 0.0 5.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99176.1 - 7.1e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON99176.1 - 7.3e-05 21.9 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EON99176.1 - 0.00059 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EON99176.1 - 0.0052 17.6 0.0 0.019 15.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 EON99176.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.4 EON99176.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 EON99176.1 - 0.022 13.7 0.0 4.2 6.2 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family FmrO PF07091.6 EON99176.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) WD40 PF00400.27 EON99177.1 - 5.4e-06 26.0 1.8 0.033 14.0 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Apc13p PF05839.6 EON99178.1 - 1.8e-29 101.5 0.1 1.9e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein PUL PF08324.6 EON99179.1 - 3.4e-43 147.3 0.0 4.7e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EON99179.1 - 3.6e-33 114.4 0.0 5.7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EON99179.1 - 6.2e-14 51.5 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EON99179.1 - 6.5e-05 23.1 0.2 0.00051 20.2 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EON99179.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EON99179.1 - 0.0018 17.7 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 EON99179.1 - 0.024 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EON99179.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin Fungal_trans PF04082.13 EON99180.1 - 1.5e-15 56.7 1.9 2.6e-15 55.9 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_Tnp_ISL3 PF01610.12 EON99180.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Transposase DUF3716 PF12511.3 EON99181.1 - 1.6e-16 59.6 6.5 2.5e-16 59.0 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Ribosomal_L1 PF00687.16 EON99182.1 - 1.8e-52 177.9 0.5 2.1e-52 177.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ABM PF03992.11 EON99183.1 - 6.9e-10 38.8 0.3 8.2e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.8 EON99183.1 - 0.072 13.0 0.1 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP Dabb PF07876.7 EON99183.1 - 0.097 13.1 0.7 0.12 12.7 0.5 1.3 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF543 PF04418.7 EON99184.1 - 1.8e-28 98.2 0.0 1.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) adh_short PF00106.20 EON99185.1 - 5.7e-18 65.3 0.0 7.9e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99185.1 - 1.4e-07 31.3 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON99185.1 - 2.7e-05 24.2 0.1 0.00021 21.3 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EON99185.1 - 0.00073 19.3 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EON99185.1 - 0.0086 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EON99185.1 - 0.015 15.0 0.3 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CoA_binding_2 PF13380.1 EON99185.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Epimerase PF01370.16 EON99185.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EON99185.1 - 0.041 13.9 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pneumovirus_M2 PF06436.6 EON99185.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) ATP-synt_ab PF00006.20 EON99185.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_19 PF14559.1 EON99186.1 - 8.7e-09 35.5 0.2 0.00013 22.2 0.0 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EON99186.1 - 2.9e-07 29.9 0.2 0.0001 21.9 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EON99186.1 - 3.8e-07 30.1 1.9 0.075 13.7 0.0 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EON99186.1 - 2.8e-05 23.6 0.6 0.0007 19.1 0.0 2.7 1 1 2 4 4 4 1 TPR repeat TPR_12 PF13424.1 EON99186.1 - 3.2e-05 23.7 3.6 0.094 12.6 0.1 3.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EON99186.1 - 0.00014 21.3 0.0 0.0006 19.3 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EON99186.1 - 0.00021 20.8 0.0 0.0031 17.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EON99186.1 - 0.0004 20.3 0.1 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON99186.1 - 0.00052 20.6 5.4 0.0075 16.9 0.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EON99186.1 - 0.00056 19.7 0.1 0.026 14.3 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Dimer_Tnp_Tn5 PF02281.11 EON99186.1 - 0.0019 18.2 0.2 0.26 11.4 0.0 2.2 1 1 1 2 2 2 1 Transposase Tn5 dimerisation domain TPR_7 PF13176.1 EON99186.1 - 0.0027 17.3 0.1 0.023 14.4 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON99186.1 - 0.0032 17.8 2.0 1.7 9.2 0.0 3.8 5 0 0 5 5 3 1 Tetratricopeptide repeat SNAP PF14938.1 EON99186.1 - 0.005 16.0 1.7 0.017 14.2 0.1 2.3 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP PPR_3 PF13812.1 EON99186.1 - 0.0086 16.2 0.1 0.075 13.3 0.0 2.4 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_20 PF14561.1 EON99186.1 - 0.015 15.4 0.4 0.83 9.8 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EON99186.1 - 0.039 14.0 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EON99186.1 - 0.063 13.5 2.1 1.9 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.5 EON99186.1 - 0.071 11.8 0.1 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EON99186.1 - 8.6 6.4 6.4 3.1 7.8 0.1 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ECH PF00378.15 EON99187.1 - 7.3e-27 94.0 0.0 8.9e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AAA_3 PF07726.6 EON99188.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EamA PF00892.15 EON99189.1 - 3e-07 30.5 3.0 3e-07 30.5 2.1 3.1 3 0 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EON99189.1 - 2.2e-06 26.7 1.7 2.2e-06 26.7 1.2 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EON99189.1 - 7.5e-06 26.1 2.7 7.5e-06 26.1 1.9 2.4 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EON99189.1 - 0.00011 21.9 2.4 0.00011 21.9 1.7 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EON99189.1 - 0.0027 16.6 1.5 0.01 14.7 0.4 2.0 2 0 0 2 2 2 1 UAA transporter family DUF3955 PF13127.1 EON99189.1 - 0.0071 15.8 0.5 0.0071 15.8 0.4 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) DUF4252 PF14060.1 EON99189.1 - 0.13 11.7 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) RasGEF PF00617.14 EON99191.1 - 6.4e-63 211.8 0.1 1.3e-62 210.9 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EON99191.1 - 2.6e-27 94.9 0.7 6.4e-27 93.7 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EON99191.1 - 8.9e-16 57.0 0.2 2e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON99191.1 - 3e-14 52.3 0.2 6.1e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EON99191.1 - 1.1e-12 47.2 0.1 2.4e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EON99191.1 - 2.4e-05 24.1 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 WW domain LCCL PF03815.14 EON99192.1 - 2.9e-21 75.2 0.2 4.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 LCCL domain SnoaL_3 PF13474.1 EON99192.1 - 0.12 12.4 0.3 0.31 11.1 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain Rifin_STEVOR PF02009.11 EON99192.1 - 0.46 10.0 0.1 0.7 9.4 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF1771 PF08590.5 EON99193.1 - 3.1e-25 87.9 9.2 5.5e-25 87.1 6.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EON99193.1 - 1.2e-16 60.7 0.4 2.6e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 Smr domain GRP PF07172.6 EON99193.1 - 0.016 15.6 7.7 0.016 15.6 5.4 1.9 2 0 0 2 2 2 0 Glycine rich protein family DUF3233 PF11557.3 EON99193.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) Spb1_C PF07780.7 EON99194.1 - 2.1e-75 252.9 26.6 2.1e-75 252.9 18.4 3.5 3 0 0 3 3 3 2 Spb1 C-terminal domain DUF3381 PF11861.3 EON99194.1 - 2.4e-56 189.6 7.3 2.4e-56 189.6 5.0 5.2 3 1 3 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EON99194.1 - 1e-54 185.2 0.0 5.3e-54 182.9 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase NUDIX-like PF09296.6 EON99195.1 - 1.2e-16 60.8 0.0 4.1e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EON99195.1 - 1.5e-16 60.2 0.0 2.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EON99195.1 - 2.4e-06 26.9 1.2 4.6e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Adaptin_N PF01602.15 EON99196.1 - 6.3e-81 272.2 0.0 1.2e-80 271.3 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EON99196.1 - 0.00043 20.5 0.2 0.14 12.4 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EON99196.1 - 0.07 13.2 0.1 42 4.5 0.0 4.7 6 0 0 6 6 6 0 HEAT repeat cwf21 PF08312.7 EON99197.1 - 4.5e-18 64.8 14.5 4.5e-18 64.8 10.0 2.1 3 0 0 3 3 3 1 cwf21 domain DUF1129 PF06570.6 EON99197.1 - 0.044 13.0 0.2 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3577 PF12101.3 EON99198.1 - 0.061 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Peptidase_S49_N PF08496.5 EON99199.1 - 3.7 7.3 6.2 8.7 6.1 4.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mito_carr PF00153.22 EON99201.1 - 2.2e-37 126.6 5.8 5.1e-16 58.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pribosyltran PF00156.22 EON99202.1 - 8.8e-10 38.3 0.3 5.1e-09 35.9 0.2 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.11 EON99203.1 - 6e-24 84.4 34.5 6e-24 84.4 23.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON99203.1 - 3.7e-10 38.9 5.5 3.7e-10 38.9 3.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2961 PF11175.3 EON99204.1 - 1.4e-57 194.7 3.3 1.7e-54 184.6 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2961) E1-E2_ATPase PF00122.15 EON99205.1 - 3.9e-65 219.0 6.8 3.9e-65 219.0 4.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EON99205.1 - 1.8e-30 105.8 0.2 1.8e-30 105.8 0.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EON99205.1 - 5.8e-27 95.5 0.1 1.1e-26 94.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EON99205.1 - 8.4e-18 63.6 0.0 2.1e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EON99205.1 - 1.5e-14 53.7 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EON99205.1 - 2.3e-13 50.7 0.0 5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EON99205.1 - 6.1e-06 26.0 1.6 7e-05 22.5 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thiolase_N PF00108.18 EON99206.1 - 4.3e-71 238.9 1.5 5.9e-71 238.5 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EON99206.1 - 7.2e-41 138.4 0.4 2e-40 137.0 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Antirestrict PF03230.8 EON99207.1 - 0.038 13.9 0.1 0.096 12.6 0.1 1.7 1 0 0 1 1 1 0 Antirestriction protein Spore_III_AF PF09581.5 EON99207.1 - 2 8.2 8.1 6.6 6.5 5.6 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DivIVA PF05103.8 EON99208.1 - 0.042 13.8 0.7 0.073 13.1 0.5 1.4 1 0 0 1 1 1 0 DivIVA protein Ter PF05472.6 EON99208.1 - 0.09 11.8 2.4 0.21 10.6 1.7 1.6 1 1 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Abhydrolase_6 PF12697.2 EON99209.1 - 8.9e-17 61.7 0.2 1.2e-16 61.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON99209.1 - 2.3e-12 46.9 0.1 7.5e-12 45.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON99209.1 - 3.8e-08 33.2 0.0 3.2e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EON99210.1 - 3.7e-26 91.6 17.7 4.2e-26 91.5 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99210.1 - 1.8e-08 33.4 11.7 2e-08 33.3 8.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2818 PF10993.3 EON99210.1 - 0.24 11.8 5.1 0.37 11.3 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) PrgI PF12666.2 EON99210.1 - 0.43 10.7 10.1 1.8 8.7 0.8 2.6 3 0 0 3 3 3 0 PrgI family protein Dynamin_N PF00350.18 EON99211.1 - 3.9e-10 39.7 0.0 6.8e-09 35.7 0.0 3.0 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EON99211.1 - 8.1e-05 22.5 0.0 0.18 11.7 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EON99211.1 - 0.013 14.6 0.4 0.072 12.1 0.0 2.3 2 1 1 3 3 3 0 Zeta toxin IIGP PF05049.8 EON99211.1 - 0.021 13.6 1.2 0.065 12.0 0.0 2.4 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EON99211.1 - 0.028 14.9 0.0 0.086 13.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EON99211.1 - 0.037 14.3 0.1 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 EON99211.1 - 0.044 13.9 0.0 25 5.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 EON99211.1 - 0.16 11.4 0.0 0.16 11.4 0.0 2.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Glyco_transf_90 PF05686.7 EON99212.1 - 1.6e-09 36.9 0.0 8.5e-09 34.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 90 ImpA-rel_N PF06812.7 EON99212.1 - 0.00025 20.7 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 ImpA-related N-terminal Sugar_tr PF00083.19 EON99213.1 - 1.1e-76 258.1 20.9 1.4e-76 257.9 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99213.1 - 8.6e-18 64.1 47.8 2.5e-16 59.3 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 EON99213.1 - 0.18 12.0 0.1 0.18 12.0 0.0 2.6 2 1 1 3 3 3 0 Divalent cation transporter MFS_1 PF07690.11 EON99215.1 - 3.1e-30 105.0 28.0 4e-30 104.7 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON99215.1 - 8.5e-14 50.9 11.9 2.4e-13 49.4 5.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EON99215.1 - 1.2e-05 23.7 4.5 1.8e-05 23.2 3.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl_transf_1 PF00698.16 EON99217.1 - 6.4e-61 206.4 0.0 9.8e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EON99217.1 - 6.8e-56 188.7 1.6 6.8e-56 188.7 1.1 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EON99217.1 - 5.2e-46 156.6 1.2 1.7e-44 151.6 1.7 2.8 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EON99217.1 - 2.8e-45 154.7 0.0 4.8e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EON99217.1 - 3e-34 117.3 0.0 1.7e-33 114.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EON99217.1 - 3.7e-15 55.6 0.0 5.9e-14 51.7 0.0 3.0 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON99217.1 - 8.2e-13 49.3 0.0 4.4e-12 46.9 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON99217.1 - 3.6e-06 26.6 1.0 1.1e-05 25.1 0.7 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EON99217.1 - 0.00016 21.8 0.7 0.00077 19.6 0.2 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 EON99217.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EON99217.1 - 0.3 10.3 2.7 0.23 10.6 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family WXG100 PF06013.7 EON99218.1 - 0.14 12.1 0.5 2.5 8.1 0.1 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG AAA PF00004.24 EON99219.1 - 9.6e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EON99219.1 - 7.7e-07 29.9 0.0 1.5e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EON99219.1 - 0.00023 20.6 0.2 0.0025 17.2 0.0 2.4 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EON99219.1 - 0.00044 20.3 0.0 0.0014 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON99219.1 - 0.0015 18.5 0.1 0.005 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EON99219.1 - 0.0033 17.2 0.0 0.0049 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EON99219.1 - 0.0043 16.1 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EON99219.1 - 0.0045 16.5 0.2 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EON99219.1 - 0.017 15.3 0.0 0.032 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EON99219.1 - 0.021 14.5 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EON99219.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EON99219.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Kinesin PF00225.18 EON99219.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain DUF948 PF06103.6 EON99220.1 - 0.0056 16.5 0.9 1.2 9.0 0.1 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) DAHP_synth_1 PF00793.15 EON99221.1 - 1.7e-101 338.5 0.1 1.9e-101 338.2 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Glyco_hydro_10 PF00331.15 EON99222.1 - 8.7e-62 208.9 0.0 1.1e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4646 PF15496.1 EON99223.1 - 0.0002 21.3 0.1 0.0031 17.5 0.0 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4646) Sugar_tr PF00083.19 EON99224.1 - 1.4e-68 231.5 12.4 1.6e-68 231.3 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EON99224.1 - 0.18 10.1 18.3 0.0063 14.9 5.9 2.2 1 1 1 2 2 2 0 MFS/sugar transport protein PAP_assoc PF03828.14 EON99225.1 - 2.1e-14 53.1 0.0 3.6e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EON99225.1 - 2.7e-08 34.0 0.0 6.7e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.17 EON99227.1 - 2.3e-35 122.0 0.0 3.4e-25 88.4 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 KNOX2 PF03791.8 EON99227.1 - 0.041 13.1 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 KNOX2 domain FAD_binding_2 PF00890.19 EON99228.1 - 3.8e-27 95.2 5.5 1.2e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EON99228.1 - 3.6e-09 36.2 1.4 2.8e-07 29.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EON99228.1 - 2e-08 33.5 3.0 4.3e-08 32.4 2.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON99228.1 - 0.00034 19.2 1.3 0.0004 18.9 0.3 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EON99228.1 - 0.001 18.1 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EON99228.1 - 0.0013 19.1 1.1 1.2 9.6 0.1 3.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99228.1 - 0.0016 18.5 0.1 0.24 11.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON99228.1 - 0.0025 17.8 1.6 0.0059 16.6 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON99228.1 - 0.0042 16.9 1.2 0.018 14.9 0.3 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EON99228.1 - 0.0078 15.3 0.1 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.17 EON99228.1 - 0.011 14.6 1.1 0.011 14.6 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EON99228.1 - 0.012 14.5 0.2 0.024 13.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EON99228.1 - 0.089 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Asp PF00026.18 EON99230.1 - 5e-51 173.8 0.6 6.4e-51 173.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON99230.1 - 1e-08 35.2 0.1 6.1e-08 32.7 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal BTB PF00651.26 EON99231.1 - 9.7e-06 25.5 0.0 3.9e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_M20 PF01546.23 EON99232.1 - 4.3e-27 94.8 0.0 6.1e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON99232.1 - 9.2e-07 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EON99232.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 NR_Repeat PF14046.1 EON99232.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor repeat Acetyltransf_1 PF00583.19 EON99233.1 - 3.4e-12 46.2 0.0 6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EON99233.1 - 1.1e-08 35.1 0.0 2.7e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EON99233.1 - 3.1e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EON99233.1 - 0.00044 19.9 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Pex24p PF06398.6 EON99234.1 - 8.3e-91 304.4 0.0 1.1e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin eIF_4EBP PF05456.6 EON99234.1 - 0.66 9.6 5.6 7.4 6.3 1.4 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF1828 PF08861.5 EON99236.1 - 0.00032 20.2 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF1828 DUF4449 PF14613.1 EON99236.1 - 0.0026 17.6 2.1 0.0046 16.9 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Abhydrolase_6 PF12697.2 EON99237.1 - 6.8e-15 55.5 0.8 8.9e-15 55.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON99237.1 - 2.9e-12 46.5 0.9 6.3e-12 45.4 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EON99237.1 - 2.3e-11 43.4 0.3 8.5e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 EON99237.1 - 0.00015 21.1 0.0 0.052 12.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EON99237.1 - 0.0013 18.3 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EON99237.1 - 0.0016 17.8 0.1 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF3089 PF11288.3 EON99237.1 - 0.0098 15.0 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_3 PF07859.8 EON99237.1 - 0.013 15.0 0.8 0.03 13.9 0.4 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EON99237.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EON99237.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Actin PF00022.14 EON99238.1 - 2.5e-72 243.4 0.0 2.9e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Actin UQ_con PF00179.21 EON99240.1 - 1e-26 93.0 0.1 1.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CoA_transf_3 PF02515.12 EON99240.1 - 0.053 12.7 0.5 0.092 11.9 0.3 1.3 1 0 0 1 1 1 0 CoA-transferase family III ABC2_membrane PF01061.19 EON99243.1 - 1.3e-96 321.7 64.0 2.4e-50 170.6 15.0 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EON99243.1 - 7.5e-36 121.9 9.1 7e-32 109.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EON99243.1 - 3.2e-35 121.4 0.0 5.6e-17 62.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 EON99243.1 - 7.5e-24 83.6 0.0 1.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EON99243.1 - 1.4e-07 31.6 0.4 8.1e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EON99243.1 - 1.9e-07 30.6 0.0 0.00047 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EON99243.1 - 6.1e-06 26.1 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EON99243.1 - 4.1e-05 22.8 0.0 0.0027 16.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EON99243.1 - 0.00015 21.2 0.7 0.026 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EON99243.1 - 0.00016 21.1 0.4 0.0054 16.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EON99243.1 - 0.00067 19.7 0.0 0.79 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EON99243.1 - 0.001 19.2 0.0 0.57 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EON99243.1 - 0.0022 18.8 0.0 0.33 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EON99243.1 - 0.0051 16.5 0.2 5 6.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EON99243.1 - 0.0062 16.2 0.4 0.95 9.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EON99243.1 - 0.0063 15.7 0.0 1.6 7.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EON99243.1 - 0.013 15.7 0.1 0.73 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EON99243.1 - 0.041 14.0 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EON99243.1 - 0.072 12.7 0.4 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EON99243.1 - 0.078 13.4 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EON99243.1 - 0.16 12.2 0.2 0.55 10.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EON99243.1 - 0.19 11.1 0.6 9 5.6 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 EON99243.1 - 0.95 8.4 0.0 1.8 7.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Macoilin PF09726.4 EON99243.1 - 1.9 6.6 10.3 2.9 6.0 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein tRNA-synt_His PF13393.1 EON99244.1 - 5.4e-39 134.0 0.0 6.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EON99244.1 - 2.1e-16 59.9 0.0 3.4e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EON99244.1 - 2.5e-05 23.2 0.0 0.0028 16.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon PF03129.15 EON99244.1 - 0.0047 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain SF-assemblin PF06705.6 EON99244.1 - 0.016 14.3 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin adh_short PF00106.20 EON99245.1 - 2e-09 37.5 0.1 2.2e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99245.1 - 0.00022 20.9 0.0 0.00025 20.7 0.0 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON99245.1 - 0.00081 19.4 0.2 0.00097 19.1 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON99245.1 - 0.0015 18.0 0.0 0.0016 17.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EON99245.1 - 0.0032 17.2 0.0 0.0038 17.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EON99245.1 - 0.065 12.4 0.1 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EON99246.1 - 8e-31 107.2 2.5 1.2e-30 106.6 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99246.1 - 2.4e-27 96.2 0.0 2.7e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99246.1 - 6.3e-12 45.5 0.6 8.7e-12 45.0 0.3 1.4 1 1 0 1 1 1 1 KR domain Kazal_1 PF00050.16 EON99247.1 - 0.03 14.3 2.2 0.12 12.3 1.5 2.1 1 1 0 1 1 1 0 Kazal-type serine protease inhibitor domain GFA PF04828.9 EON99248.1 - 0.00045 20.1 0.3 0.16 11.9 0.0 3.1 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme UFD1 PF03152.9 EON99249.1 - 1.1e-24 86.5 0.0 4.4e-20 71.5 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 zf-C2H2 PF00096.21 EON99249.1 - 0.13 12.6 13.9 0.31 11.4 0.5 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type PRP21_like_P PF12230.3 EON99249.1 - 0.46 9.9 3.0 0.28 10.6 0.0 2.1 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Alkyl_sulf_dimr PF14863.1 EON99250.1 - 8e-49 165.4 0.6 1.9e-48 164.3 0.4 1.6 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 EON99250.1 - 9.4e-20 71.0 0.9 1.5e-19 70.4 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 EON99250.1 - 3.6e-12 46.3 0.0 7.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 EON99250.1 - 0.00024 20.7 0.8 0.00065 19.3 0.4 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EON99250.1 - 0.12 12.0 0.2 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DPM3 PF08285.6 EON99252.1 - 2.7e-31 107.2 0.1 3.1e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WSC PF01822.14 EON99253.1 - 1e-54 182.3 53.6 1.5e-20 72.8 8.7 3.6 3 0 0 3 3 3 3 WSC domain PQQ_3 PF13570.1 EON99253.1 - 0.00036 20.7 14.3 0.062 13.5 0.0 5.7 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.1 EON99253.1 - 0.0025 17.3 6.9 0.048 13.1 0.0 4.2 5 0 0 5 5 5 2 PQQ-like domain Sugar_tr PF00083.19 EON99254.1 - 6.6e-42 143.6 7.7 3e-30 105.2 1.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EON99254.1 - 1.3e-12 47.1 13.9 4e-12 45.5 9.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EON99255.1 - 2.8e-24 85.3 0.0 4.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 EON99256.1 - 1.6e-13 50.3 4.4 1.5e-12 47.1 3.1 2.2 1 1 0 1 1 1 1 Dioxygenase MG1 PF11974.3 EON99256.1 - 0.028 14.9 0.1 0.08 13.5 0.1 1.8 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Methyltransf_11 PF08241.7 EON99258.1 - 1.1e-13 51.4 0.0 3.5e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON99258.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99258.1 - 4e-12 46.3 0.0 1e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99258.1 - 8.1e-11 42.4 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99258.1 - 1.8e-08 34.7 0.0 3.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99258.1 - 1.1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON99258.1 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EON99258.1 - 1.4e-05 24.5 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EON99258.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EON99258.1 - 0.00024 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EON99258.1 - 0.0021 17.1 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 EON99258.1 - 0.0034 16.6 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Fibrillarin PF01269.12 EON99258.1 - 0.033 13.1 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Fibrillarin CheR PF01739.13 EON99258.1 - 0.08 12.2 0.0 0.23 10.7 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Spore_YpjB PF09577.5 EON99258.1 - 0.093 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Pkinase PF00069.20 EON99259.1 - 6e-11 41.9 0.0 9.3e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99259.1 - 5.4e-06 25.6 0.0 7.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EON99259.1 - 7.4e-06 25.1 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EON99259.1 - 6.8e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EON99259.1 - 0.00038 20.2 0.1 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EON99259.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EON99259.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Vint PF14623.1 EON99260.1 - 1e-48 164.8 0.0 1.7e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EON99260.1 - 2.7e-30 104.2 0.0 5.5e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.23 EON99260.1 - 2e-18 66.7 0.0 3.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EON99260.1 - 7.7e-17 61.9 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EON99260.1 - 3.2e-11 43.1 0.0 2.4e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.15 EON99260.1 - 0.032 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Hint module vWA-TerF-like PF10138.4 EON99260.1 - 0.043 13.6 0.3 0.43 10.3 0.2 2.1 1 1 0 1 1 1 0 vWA found in TerF C terminus 2-Hacid_dh_C PF02826.14 EON99262.1 - 5.9e-32 110.2 0.0 2e-31 108.5 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON99262.1 - 0.00013 21.4 0.0 0.00014 21.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Bac_surface_Ag PF01103.18 EON99263.1 - 8.8e-39 133.8 0.2 1.2e-38 133.4 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Aldo_ket_red PF00248.16 EON99265.1 - 3.1e-47 160.7 0.0 6.3e-46 156.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Alpha-L-AF_C PF06964.7 EON99266.1 - 3.9e-28 98.4 0.0 6.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus COX14 PF14880.1 EON99267.1 - 1.5e-18 66.1 0.4 1.5e-18 66.1 0.3 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly EF1_GNE PF00736.14 EON99268.1 - 2e-09 36.9 0.0 2.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain UBA_3 PF09288.5 EON99268.1 - 0.086 12.4 0.2 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain ABC_tran PF00005.22 EON99270.1 - 4.5e-05 23.7 0.1 7.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EON99270.1 - 0.0016 19.2 0.1 0.0035 18.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EON99270.1 - 0.0019 17.6 0.1 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EON99270.1 - 0.0029 17.1 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EON99270.1 - 0.0032 17.4 0.1 0.0041 17.1 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EON99270.1 - 0.0045 17.1 0.0 0.0071 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EON99270.1 - 0.0056 15.8 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EON99270.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EON99270.1 - 0.013 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EON99270.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EON99270.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EON99270.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EON99270.1 - 0.048 13.6 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EON99270.1 - 0.065 13.0 1.0 0.25 11.1 0.1 2.2 3 0 0 3 3 3 0 Part of AAA domain AAA_23 PF13476.1 EON99270.1 - 0.081 13.2 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EON99270.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EON99270.1 - 0.098 12.0 0.7 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EON99270.1 - 0.13 11.8 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L13e PF01294.13 EON99271.1 - 1.2e-66 223.5 4.8 1.8e-66 223.0 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e FMO-like PF00743.14 EON99272.1 - 1.8e-53 181.5 0.0 4.5e-53 180.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EON99272.1 - 7.7e-17 62.0 0.0 4e-16 59.6 0.0 2.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EON99272.1 - 1.4e-09 37.8 0.0 5.1e-09 36.0 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON99272.1 - 1.3e-07 31.6 0.0 4e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON99272.1 - 1.3e-06 27.5 0.2 0.15 10.9 0.0 4.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EON99272.1 - 3.2e-06 26.9 0.6 0.00025 20.8 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EON99272.1 - 5.9e-06 25.4 0.0 0.0015 17.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON99272.1 - 2.7e-05 24.5 0.0 0.0001 22.6 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EON99272.1 - 4.3e-05 22.7 0.0 0.0007 18.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EON99272.1 - 0.00021 20.4 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EON99272.1 - 0.00038 19.0 0.0 0.00098 17.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EON99272.1 - 0.0064 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EON99272.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EON99272.1 - 0.018 15.3 0.0 4.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EON99272.1 - 0.029 14.4 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EON99272.1 - 0.033 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EON99272.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EON99272.1 - 0.05 12.9 0.1 0.68 9.2 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_oxidored PF12831.2 EON99272.1 - 0.15 11.1 0.2 0.6 9.1 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EON99272.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_A4 PF01828.12 EON99273.1 - 2.3e-20 72.5 0.0 2.8e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family Acetyltransf_1 PF00583.19 EON99274.1 - 8.6e-08 32.1 0.2 1.8e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EON99274.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 EON99274.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L50 PF10501.4 EON99275.1 - 8.3e-25 86.9 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.22 EON99275.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 SAP domain FMN_red PF03358.10 EON99276.1 - 1.4e-23 83.0 0.0 2.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EON99276.1 - 0.0032 17.0 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Peripla_BP_6 PF13458.1 EON99276.1 - 0.044 13.1 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein bZIP_1 PF00170.16 EON99277.1 - 5.8e-05 22.9 6.6 0.0001 22.1 4.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EON99277.1 - 0.0016 18.1 6.8 0.003 17.3 4.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF2052 PF09747.4 EON99277.1 - 0.11 12.4 3.9 0.15 11.9 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) U79_P34 PF03064.11 EON99277.1 - 1.2 8.5 6.9 1.6 8.1 4.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 A_deaminase PF00962.17 EON99278.1 - 1.6e-42 145.5 0.0 1.3e-38 132.7 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Tetraspannin PF00335.15 EON99279.1 - 0.25 10.5 5.1 0.21 10.8 0.4 2.2 2 0 0 2 2 2 0 Tetraspanin family PepSY_TM PF03929.11 EON99279.1 - 0.48 10.9 3.7 2.1 8.8 0.2 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2892 PF11127.3 EON99279.1 - 1.6 8.5 11.7 1.4 8.8 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF2964 PF11177.3 EON99279.1 - 6.4 6.7 7.4 0.29 11.1 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) CIA30 PF08547.7 EON99280.1 - 7e-35 120.2 0.1 8.1e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sulfotransfer_3 PF13469.1 EON99281.1 - 0.00015 22.7 0.1 0.00021 22.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_M48 PF01435.13 EON99282.1 - 2.2e-40 138.6 0.0 2.8e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 SpecificRecomb PF10136.4 EON99282.1 - 0.00089 17.4 0.2 0.0014 16.7 0.1 1.2 1 0 0 1 1 1 1 Site-specific recombinase Rho_N PF07498.7 EON99283.1 - 0.036 13.8 0.4 0.063 13.0 0.3 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF3405 PF11885.3 EON99284.1 - 6.2e-195 648.1 0.8 6.2e-195 648.1 0.6 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DnaJ PF00226.26 EON99285.1 - 3.9e-15 55.3 0.1 6.1e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ni_hydr_CYTB PF01292.15 EON99286.1 - 0.012 15.0 5.5 0.048 13.0 3.8 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF350 PF03994.9 EON99286.1 - 0.72 9.6 9.9 0.088 12.5 2.5 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF350) DUF1129 PF06570.6 EON99286.1 - 1.6 7.9 4.3 0.92 8.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Kelch_3 PF13415.1 EON99287.1 - 2.1e-26 91.4 16.9 2.3e-06 27.5 0.0 8.0 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EON99287.1 - 8.1e-22 76.7 13.2 1.2e-06 28.1 0.0 7.2 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EON99287.1 - 2.8e-16 59.0 4.3 7.7e-05 22.5 0.0 6.2 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 EON99287.1 - 4.1e-15 55.2 3.8 4.7e-05 23.3 0.0 5.9 5 2 2 7 7 7 3 Kelch motif Kelch_1 PF01344.20 EON99287.1 - 2e-11 43.2 2.4 0.00022 20.6 0.1 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EON99287.1 - 6e-09 35.3 3.4 1.5e-05 24.5 0.3 4.8 4 1 0 4 4 4 1 Kelch motif TPR_12 PF13424.1 EON99288.1 - 1.1e-06 28.4 7.6 0.00015 21.6 0.2 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON99288.1 - 1.5e-05 24.4 0.9 0.81 9.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EON99288.1 - 2.8e-05 23.6 4.7 0.03 13.9 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EON99288.1 - 0.0002 21.0 10.9 0.0022 17.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EON99288.1 - 0.0014 18.5 1.0 0.022 14.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EON99288.1 - 0.0079 16.8 1.4 1 10.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EON99288.1 - 0.12 11.9 7.1 1.2 8.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EON99288.1 - 0.13 12.9 4.6 0.59 10.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EON99288.1 - 1.9 8.3 5.7 0.38 10.6 0.4 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat AMP-binding PF00501.23 EON99289.1 - 4.5e-41 140.5 0.0 5.6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON99289.1 - 1.2e-10 42.1 0.2 2.4e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pilin_PilX PF11530.3 EON99289.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Minor type IV pilin, PilX Trehalase PF01204.13 EON99291.1 - 2.1e-193 643.6 0.0 2.6e-193 643.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EON99291.1 - 3.9e-17 61.2 0.6 6.6e-17 60.5 0.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF3129 PF11327.3 EON99292.1 - 1.4e-70 236.8 10.1 2e-70 236.3 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Glyco_hydro_61 PF03443.9 EON99293.1 - 2.5e-65 220.3 0.1 2.9e-65 220.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2Fe-2S_thioredx PF01257.14 EON99294.1 - 2.1e-58 196.0 0.0 2.5e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NMT1 PF09084.6 EON99294.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Senescence PF06911.7 EON99294.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Senescence-associated protein Glyco_trans_2_3 PF13632.1 EON99295.1 - 2.2e-48 164.5 1.7 2.2e-48 164.5 1.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON99295.1 - 1.1e-07 31.9 0.1 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EON99295.1 - 3.1e-06 26.9 0.0 1.4e-05 24.8 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EON99295.1 - 6.3e-05 22.3 0.1 0.00017 20.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 NmrA PF05368.8 EON99297.1 - 1.3e-11 44.1 0.0 2.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON99297.1 - 6e-10 39.4 0.1 1.1e-09 38.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON99297.1 - 0.00011 21.6 0.0 0.0038 16.6 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EON99297.1 - 0.00078 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EON99297.1 - 0.0041 16.0 0.0 0.013 14.4 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein TraI_2 PF07514.6 EON99297.1 - 0.018 13.8 0.0 0.056 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative helicase Isochorismatase PF00857.15 EON99297.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Isochorismatase family F420_oxidored PF03807.12 EON99297.1 - 0.081 13.3 0.2 0.25 11.8 0.1 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4386 PF14329.1 EON99298.1 - 0.022 14.2 1.8 0.052 13.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) ThiF PF00899.16 EON99299.1 - 2.2e-28 98.7 0.0 3.9e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EON99299.1 - 0.019 15.0 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-C2H2_4 PF13894.1 EON99300.1 - 0.00027 21.0 12.5 0.13 12.6 0.2 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EON99300.1 - 0.03 14.6 18.6 1.8 9.0 0.2 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EON99300.1 - 0.031 14.4 8.1 1.2 9.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EON99300.1 - 0.098 12.8 4.1 5.8 7.2 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EON99300.1 - 0.15 12.4 7.2 0.13 12.6 0.7 2.8 2 1 0 2 2 2 0 TRAF-type zinc finger Phosphoesterase PF04185.9 EON99301.1 - 7.4e-79 265.6 0.2 7.4e-79 265.6 0.2 1.4 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.8 EON99301.1 - 0.00027 20.9 0.1 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 Fascin domain DUF4241 PF14025.1 EON99301.1 - 0.039 13.7 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) LRR_6 PF13516.1 EON99302.1 - 0.016 15.2 9.0 33 4.9 0.0 6.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 EON99302.1 - 0.68 9.6 10.4 2 8.1 0.3 5.1 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) Ribosomal_L18p PF00861.17 EON99303.1 - 5.1e-43 146.0 0.4 1.6e-42 144.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EON99303.1 - 4.8e-34 116.7 11.3 4.8e-34 116.7 7.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region RRM_1 PF00076.17 EON99304.1 - 2.2e-37 126.5 0.2 7.9e-18 63.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99304.1 - 5.5e-29 99.9 0.6 2.2e-13 49.9 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99304.1 - 5.7e-12 45.3 3.6 8.3e-06 25.5 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EON99304.1 - 0.0065 16.2 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EON99304.1 - 0.081 12.7 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Glyco_hydro_16 PF00722.16 EON99305.1 - 5.2e-07 29.1 0.6 1.9e-05 24.0 0.4 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Hormone_4 PF00220.12 EON99305.1 - 0.17 11.5 2.4 9.8 6.1 0.1 3.1 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain MFS_1 PF07690.11 EON99306.1 - 1.2e-43 149.1 29.5 1.2e-43 149.1 20.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyt-b5 PF00173.23 EON99307.1 - 5.6e-19 67.7 0.5 6.1e-19 67.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EON99307.1 - 0.12 12.3 0.1 0.4 10.5 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H DUF1367 PF07105.6 EON99307.1 - 0.12 11.8 0.1 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1367) bZIP_1 PF00170.16 EON99308.1 - 1.6e-09 37.5 4.2 1.6e-09 37.5 2.9 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EON99308.1 - 1.9e-05 24.3 4.1 1.9e-05 24.3 2.8 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EON99308.1 - 0.026 14.7 8.0 0.026 14.7 5.5 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor ORC6 PF05460.8 EON99308.1 - 0.039 13.0 4.9 0.047 12.7 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF745 PF05335.8 EON99308.1 - 0.044 13.3 3.5 0.055 12.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BCL9 PF11502.3 EON99308.1 - 0.067 12.7 0.3 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein GAS PF13851.1 EON99308.1 - 0.091 11.9 3.2 0.12 11.5 2.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4570 PF15134.1 EON99308.1 - 0.35 10.7 5.4 0.54 10.1 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) IncA PF04156.9 EON99308.1 - 0.48 9.9 2.7 0.62 9.6 1.9 1.1 1 0 0 1 1 1 0 IncA protein DUF3391 PF11871.3 EON99308.1 - 9.7 6.4 7.2 16 5.7 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SHNi-TPR PF10516.4 EON99309.1 - 7.9e-15 53.8 0.1 7.9e-15 53.8 0.1 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EON99309.1 - 4.4e-10 39.3 3.6 2.2e-05 24.2 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON99309.1 - 1.3e-06 28.8 4.4 1.6e-06 28.6 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EON99309.1 - 2.2e-06 27.2 7.0 0.00019 21.0 0.5 2.9 2 1 0 2 2 2 2 TPR repeat Apc3 PF12895.2 EON99309.1 - 0.0001 22.3 0.5 0.032 14.3 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EON99309.1 - 0.00018 21.7 1.3 0.00074 19.8 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 EON99309.1 - 0.0029 17.3 3.4 0.0077 16.0 2.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EON99309.1 - 0.37 10.8 15.3 0.1 12.5 2.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EON99309.1 - 1.4 8.9 6.1 0.43 10.5 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EON99309.1 - 1.4 9.7 5.1 1.6 9.5 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ICL PF00463.16 EON99310.1 - 4.3e-283 939.2 1.4 4.9e-283 939.0 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EON99310.1 - 4.1e-12 45.8 0.1 2e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fork_head PF00250.13 EON99311.1 - 3.9e-13 49.2 0.0 8.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EON99311.1 - 9.9e-05 22.3 0.1 0.00021 21.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain NAD_binding_5 PF07994.7 EON99312.1 - 6.2e-112 373.8 0.2 7.7e-112 373.5 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EON99312.1 - 1.1e-45 153.9 0.6 2.2e-45 153.0 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Cyt-b5 PF00173.23 EON99313.1 - 1.2e-16 60.2 0.0 1.4e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain dCMP_cyt_deam_1 PF00383.17 EON99315.1 - 2.1e-26 91.4 1.4 3.1e-26 90.9 1.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EON99315.1 - 1.4e-08 35.6 0.1 6.2e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EON99315.1 - 1.6e-05 25.2 0.1 0.00012 22.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EON99315.1 - 0.025 13.9 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase PhyH PF05721.8 EON99316.1 - 1.1e-62 211.8 0.0 1.3e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EON99316.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PMT PF02366.13 EON99317.1 - 5.3e-78 261.7 15.5 5.3e-78 261.7 10.7 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EON99317.1 - 2e-37 128.5 0.2 2.7e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 EON99317.1 - 0.03 13.8 3.7 0.21 11.1 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) RabGAP-TBC PF00566.13 EON99318.1 - 3e-46 157.5 0.0 3e-46 157.5 0.0 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CCDC155 PF14662.1 EON99318.1 - 0.0014 18.2 27.6 0.0014 18.2 19.2 3.4 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 PilJ PF13675.1 EON99318.1 - 0.63 10.3 15.9 0.13 12.5 1.2 3.3 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Snf7 PF03357.16 EON99319.1 - 2.9e-34 117.9 11.9 3.6e-34 117.5 8.2 1.1 1 0 0 1 1 1 1 Snf7 CbiG_C PF01890.11 EON99319.1 - 0.096 12.9 0.7 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus PMSR PF01625.16 EON99319.1 - 0.28 11.0 1.4 10 5.9 0.1 2.3 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase DUF2203 PF09969.4 EON99319.1 - 0.4 10.8 3.7 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.7 EON99319.1 - 2.6 6.3 6.3 6.9 4.9 0.7 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family HEXIM PF15313.1 EON99320.1 - 0.015 15.4 1.5 0.034 14.2 1.0 1.6 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein CUE PF02845.11 EON99321.1 - 3.5e-13 48.7 0.0 7.8e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain LicD PF04991.8 EON99322.1 - 3.9e-38 131.6 4.0 7.2e-37 127.4 2.8 2.1 1 1 0 1 1 1 1 LicD family CENP-Q PF13094.1 EON99323.1 - 8e-34 116.9 0.3 8e-34 116.9 0.2 2.8 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Spore_SspJ PF09575.5 EON99324.1 - 0.0084 16.2 2.0 0.049 13.8 0.1 2.7 2 0 0 2 2 2 1 Small spore protein J (Spore_SspJ) DUF2937 PF11157.3 EON99324.1 - 0.021 14.1 0.5 0.037 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) CRM1_C PF08767.6 EON99325.1 - 1.6e-130 434.7 1.1 1.6e-130 434.7 0.8 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EON99325.1 - 2.3e-41 141.1 12.6 3.5e-41 140.5 6.2 3.2 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EON99325.1 - 3.3e-10 39.7 0.7 1.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EON99325.1 - 0.017 15.0 4.7 0.15 11.9 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 EON99325.1 - 0.12 12.7 3.4 0.98 9.8 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Ydc2-catalyt PF09159.5 EON99326.1 - 6.3e-27 94.7 0.2 7e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF2582 PF10771.4 EON99326.1 - 0.015 15.1 0.2 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) Herpes_BLRF2 PF05812.7 EON99326.1 - 0.067 12.9 0.9 0.098 12.4 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Aa_trans PF01490.13 EON99327.1 - 1.5e-19 69.8 12.6 1.7e-19 69.6 8.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EON99327.1 - 0.011 14.4 0.9 0.011 14.4 0.6 2.1 2 1 0 2 2 2 0 Spore germination protein SKG6 PF08693.5 EON99328.1 - 0.066 12.5 0.3 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_S6e PF01092.14 EON99329.1 - 7.3e-64 213.1 0.3 1.4e-63 212.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 EON99329.1 - 0.091 12.8 0.3 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region WLM PF08325.5 EON99330.1 - 7.8e-48 162.8 0.1 1.7e-47 161.6 0.0 1.5 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EON99330.1 - 0.0015 18.4 0.8 0.0015 18.4 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.1 EON99330.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 SprT-like PF10263.4 EON99330.1 - 0.016 14.8 0.2 0.016 14.8 0.2 1.7 1 1 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 EON99330.1 - 0.099 12.6 2.3 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily SelP_N PF04592.9 EON99330.1 - 0.26 10.6 5.0 0.46 9.8 3.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MCM2_N PF12619.3 EON99330.1 - 4.8 7.1 14.0 0.25 11.3 4.9 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 ERCC4 PF02732.10 EON99331.1 - 6e-23 81.1 0.0 1.1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Pga1 PF10333.4 EON99332.1 - 0.002 17.8 1.3 0.0042 16.7 0.0 1.9 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator UPF0542 PF15086.1 EON99332.1 - 0.077 12.7 0.1 22 4.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 UPF0542 PF15086.1 EON99333.1 - 0.006 16.2 0.2 0.0069 16.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 Nckap1 PF09735.4 EON99333.1 - 0.014 12.9 0.1 0.016 12.7 0.1 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein PgaD PF13994.1 EON99333.1 - 0.053 13.0 0.0 0.061 12.7 0.0 1.0 1 0 0 1 1 1 0 PgaD-like protein UPF0560 PF10577.4 EON99333.1 - 0.067 11.4 0.1 0.078 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1206 PF06724.6 EON99333.1 - 0.077 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SHR3_chaperone PF08229.6 EON99333.1 - 0.088 11.7 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF1687 PF07955.6 EON99334.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Pro_isomerase PF00160.16 EON99335.1 - 5e-42 143.7 0.0 9e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1266 PF06889.6 EON99335.1 - 0.042 13.6 0.4 0.1 12.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Ribosomal_S8e PF01201.17 EON99337.1 - 7.5e-48 162.0 2.5 9.2e-48 161.7 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EON99337.1 - 0.09 13.0 6.2 0.36 11.1 4.3 2.0 1 1 0 1 1 1 0 Small acidic protein family OB_NTP_bind PF07717.11 EON99338.1 - 3.1e-24 84.9 0.0 9.2e-24 83.4 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EON99338.1 - 1.1e-19 70.2 0.1 2.4e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EON99338.1 - 4.2e-11 42.5 0.0 9.6e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EON99338.1 - 0.033 13.6 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NifU PF01106.12 EON99339.1 - 1.9e-22 78.7 0.1 3.3e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 EON99339.1 - 4.5e-15 55.0 0.2 3.9e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal ATP-synt_ab PF00006.20 EON99340.1 - 4.2e-61 206.1 0.0 5.4e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EON99340.1 - 3.9e-18 65.9 0.1 7.2e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EON99340.1 - 0.00015 21.9 0.2 0.00036 20.6 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EON99340.1 - 0.00084 19.2 0.2 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain ATP-grasp_2 PF08442.5 EON99341.1 - 2.9e-07 30.0 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Pyr_redox_2 PF07992.9 EON99342.1 - 5.4e-37 127.6 0.7 8.5e-37 126.9 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EON99342.1 - 3.7e-34 117.0 0.4 4.4e-33 113.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EON99342.1 - 3.1e-19 69.1 4.6 7.2e-18 64.7 0.0 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99342.1 - 3.6e-10 40.2 0.0 2.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON99342.1 - 6.9e-07 28.4 0.0 6.4e-06 25.3 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EON99342.1 - 2.6e-05 22.8 4.6 0.032 12.6 0.0 3.2 2 1 1 3 3 3 3 HI0933-like protein 3HCDH_N PF02737.13 EON99342.1 - 0.0073 15.9 0.1 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EON99342.1 - 0.0077 15.1 0.5 0.084 11.7 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EON99342.1 - 0.011 15.3 0.6 0.32 10.5 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EON99342.1 - 0.033 13.2 0.0 0.074 12.1 0.0 1.7 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 EON99342.1 - 0.054 12.6 0.8 0.21 10.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EON99342.1 - 0.06 12.4 0.1 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EON99342.1 - 0.12 11.4 0.8 8.2 5.3 0.2 2.4 2 0 0 2 2 2 0 FAD binding domain Glypican PF01153.14 EON99343.1 - 0.18 10.4 1.6 0.31 9.5 1.1 1.4 1 0 0 1 1 1 0 Glypican Strep_his_triad PF04270.8 EON99343.1 - 1.7 8.4 5.5 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Streptococcal histidine triad protein Steroid_dh PF02544.11 EON99344.1 - 1.1e-22 80.4 0.3 1.9e-22 79.6 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EON99344.1 - 0.0019 17.5 0.2 0.003 16.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF621 PF04789.10 EON99344.1 - 0.021 13.8 1.3 0.03 13.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) PEMT PF04191.8 EON99344.1 - 0.21 11.7 2.3 0.21 11.6 0.0 2.2 3 0 0 3 3 3 0 Phospholipid methyltransferase zf-ZPR1 PF03367.8 EON99346.1 - 2.8e-105 348.4 0.0 1.9e-51 173.4 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain RasGEF PF00617.14 EON99347.1 - 5.3e-43 146.9 0.0 7.1e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain Spindle_Spc25 PF08234.7 EON99348.1 - 5.5e-24 83.9 0.2 1.5e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Syntaphilin PF15290.1 EON99348.1 - 0.04 13.3 1.5 0.04 13.3 1.0 2.1 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Atg14 PF10186.4 EON99348.1 - 0.12 11.3 10.4 0.038 12.9 5.1 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 EON99348.1 - 0.26 10.7 15.0 0.067 12.6 8.1 1.6 2 0 0 2 2 2 0 Intermediate filament protein DUF848 PF05852.6 EON99348.1 - 0.42 10.4 10.8 0.4 10.5 5.0 2.5 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.7 EON99348.1 - 1.7 8.4 6.4 1.3 8.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.7 EON99348.1 - 2.5 6.4 6.6 2.9 6.2 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EON99348.1 - 3.2 6.0 6.7 5.3 5.3 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 EON99348.1 - 3.9 7.7 8.2 2 8.7 3.6 1.8 2 0 0 2 2 2 0 AAA domain Tudor-knot PF11717.3 EON99349.1 - 2.9e-08 33.3 1.4 5.2e-08 32.4 1.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EON99349.1 - 0.018 14.7 1.4 0.029 14.0 1.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Calsarcin PF05556.6 EON99349.1 - 0.04 13.1 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Cytochrom_C PF00034.16 EON99350.1 - 1.2e-09 38.8 0.0 1.7e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EON99350.1 - 4e-08 33.2 1.9 1.8e-07 31.1 1.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EON99350.1 - 0.0025 17.2 0.2 0.0087 15.5 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Ras PF00071.17 EON99351.1 - 2.2e-49 166.9 0.0 4.2e-38 130.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EON99351.1 - 2.2e-16 60.4 0.0 2.9e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EON99351.1 - 1.7e-11 43.6 0.0 2.3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EON99351.1 - 6.5e-07 28.9 0.1 6.3e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EON99351.1 - 1.2e-06 27.9 0.0 6.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EON99351.1 - 0.001 19.0 0.0 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EON99351.1 - 0.013 14.8 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EON99351.1 - 0.03 14.4 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EON99351.1 - 0.071 12.5 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EON99351.1 - 0.18 11.8 0.9 0.36 10.8 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain COesterase PF00135.23 EON99352.1 - 7.1e-86 289.0 0.0 1.1e-85 288.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EON99352.1 - 0.0009 18.8 0.4 0.0047 16.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold ER_lumen_recept PF00810.13 EON99354.1 - 1.5e-54 184.4 7.7 2.4e-54 183.8 5.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EON99354.1 - 0.1 12.1 8.5 1.7 8.2 0.2 3.5 2 1 1 3 3 3 0 PQ loop repeat HSP70 PF00012.15 EON99355.1 - 1.1e-119 400.1 2.4 1.3e-92 310.7 0.1 3.0 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 EON99355.1 - 2.5e-07 29.6 0.1 3.9e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DUF3089 PF11288.3 EON99355.1 - 0.036 13.2 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) RNase_PH PF01138.16 EON99357.1 - 6.2e-10 39.4 0.0 1.6e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 CoA_binding PF02629.14 EON99358.1 - 2.6e-19 69.5 0.3 6.8e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 EON99358.1 - 3.7e-19 68.6 0.0 2.1e-16 59.6 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EON99358.1 - 1.3e-15 57.3 0.1 3.3e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EON99358.1 - 3.1e-06 26.8 0.0 0.00018 21.1 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EON99358.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Aminotran_5 PF00266.14 EON99359.1 - 8.8e-27 93.7 0.0 1.1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EON99359.1 - 4.6e-05 22.5 0.0 7.8e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 EON99359.1 - 0.00022 21.0 0.1 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain DUF521 PF04412.8 EON99359.1 - 0.094 11.2 0.1 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ribosomal_S5_C PF03719.10 EON99360.1 - 2e-18 65.3 0.0 4.2e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EON99360.1 - 2.8e-10 39.7 0.5 5.7e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PSP1 PF04468.7 EON99361.1 - 9.9e-30 102.3 0.7 1.8e-29 101.5 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_S7 PF00949.16 EON99361.1 - 0.053 12.9 0.6 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease GSG-1 PF07803.6 EON99361.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 GSG1-like protein DUF2293 PF10056.4 EON99362.1 - 7.4e-23 80.3 0.0 1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) WW PF00397.21 EON99363.1 - 7.4e-08 32.1 2.2 1.2e-07 31.4 1.5 1.4 1 0 0 1 1 1 1 WW domain Tom5 PF10642.4 EON99363.1 - 0.74 9.5 3.3 0.78 9.4 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Kinesin PF00225.18 EON99364.1 - 7.1e-59 199.1 2.5 7.6e-58 195.8 0.4 4.2 4 1 1 5 5 5 2 Kinesin motor domain MRG PF05712.8 EON99365.1 - 2.1e-49 167.1 0.0 3.5e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 MRG AAA PF00004.24 EON99366.1 - 1e-82 274.8 0.0 2.3e-46 157.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EON99366.1 - 2.8e-15 55.9 0.1 1.2e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EON99366.1 - 2.3e-13 50.5 2.0 1.8e-06 28.0 0.0 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EON99366.1 - 3.2e-13 50.5 0.2 8.5e-07 29.8 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EON99366.1 - 1.2e-12 48.1 1.0 0.0034 17.5 0.0 5.7 4 2 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EON99366.1 - 3e-11 43.3 0.0 6.7e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EON99366.1 - 6.4e-11 42.1 0.7 1.3e-05 24.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EON99366.1 - 7.7e-11 41.9 0.0 6e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EON99366.1 - 1.5e-09 37.4 0.3 0.00033 20.3 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain AAA_2 PF07724.9 EON99366.1 - 1.6e-09 37.9 0.0 0.00021 21.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EON99366.1 - 1.1e-07 31.9 0.0 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EON99366.1 - 1.2e-07 32.1 0.7 0.0032 17.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EON99366.1 - 1.9e-07 31.1 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EON99366.1 - 3.1e-07 29.9 0.2 0.026 13.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EON99366.1 - 1.2e-06 27.8 0.0 0.004 16.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.10 EON99366.1 - 1.7e-06 27.0 0.0 0.0029 16.3 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Cytidylate_kin2 PF13189.1 EON99366.1 - 2.7e-06 27.3 0.0 0.0055 16.6 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase-like family Mg_chelatase PF01078.16 EON99366.1 - 3.5e-06 26.3 0.2 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EON99366.1 - 3.9e-06 25.8 0.1 0.075 11.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus ABC_tran PF00005.22 EON99366.1 - 4.6e-06 26.9 0.0 0.033 14.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EON99366.1 - 5.9e-06 25.7 0.0 0.00023 20.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EON99366.1 - 8.5e-06 25.5 1.1 0.016 14.8 0.0 3.6 3 1 1 4 4 4 1 NACHT domain Sigma54_activat PF00158.21 EON99366.1 - 1.8e-05 24.2 0.0 0.049 13.0 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain SKI PF01202.17 EON99366.1 - 4e-05 23.5 0.1 0.33 10.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase AAA_3 PF07726.6 EON99366.1 - 5.5e-05 22.7 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EON99366.1 - 7.8e-05 22.7 0.0 0.079 12.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EON99366.1 - 8.9e-05 22.1 0.0 0.025 14.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EON99366.1 - 9e-05 21.9 11.6 0.19 11.1 0.3 4.6 2 2 2 4 4 4 1 AAA domain AAA_23 PF13476.1 EON99366.1 - 0.00021 21.7 1.8 0.0012 19.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 EON99366.1 - 0.0003 19.7 0.0 0.54 9.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EON99366.1 - 0.00042 19.6 0.3 0.25 10.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 EON99366.1 - 0.00053 18.9 0.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EON99366.1 - 0.00069 19.3 0.2 1.6 8.4 0.0 3.1 2 1 1 3 3 3 1 NTPase Vps4_C PF09336.5 EON99366.1 - 0.0014 18.5 0.0 0.0044 16.8 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.13 EON99366.1 - 0.0016 17.9 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EON99366.1 - 0.002 17.8 0.0 2.6 7.6 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 EON99366.1 - 0.0033 17.2 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 EON99366.1 - 0.0037 16.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EON99366.1 - 0.0037 16.8 0.7 2.2 7.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EON99366.1 - 0.0047 16.4 0.0 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 EON99366.1 - 0.0054 15.8 0.0 0.71 8.9 0.0 2.7 2 0 0 2 2 2 1 KaiC SRPRB PF09439.5 EON99366.1 - 0.0078 15.4 0.3 14 4.8 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit T2SE PF00437.15 EON99366.1 - 0.013 14.4 0.2 4 6.2 0.0 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.12 EON99366.1 - 0.017 14.0 0.1 4.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF258 PF03193.11 EON99366.1 - 0.03 13.4 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Bac_DnaA PF00308.13 EON99366.1 - 0.034 13.8 0.1 14 5.2 0.1 3.1 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_30 PF13604.1 EON99366.1 - 0.044 13.3 0.4 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EON99366.1 - 0.062 12.8 0.0 4.1 6.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain CPT PF07931.7 EON99366.1 - 0.063 12.9 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MCM PF00493.18 EON99366.1 - 0.11 11.3 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family HSF_DNA-bind PF00447.12 EON99367.1 - 2.5e-26 91.8 0.5 6.9e-26 90.4 0.4 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Helicase_C PF00271.26 EON99368.1 - 2.6e-19 68.8 0.0 4.4e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EON99368.1 - 8.1e-05 22.1 0.0 0.00037 20.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF913 PF06025.7 EON99369.1 - 6.6e-114 380.5 0.1 6.6e-114 380.5 0.0 3.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EON99369.1 - 1.9e-97 326.2 0.1 6.4e-97 324.5 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EON99369.1 - 5.9e-40 137.5 3.8 3.4e-32 112.0 0.3 4.1 3 1 1 4 4 4 2 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EON99369.1 - 4.9e-33 113.2 9.0 4.9e-33 113.2 6.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) DUF1761 PF08570.5 EON99369.1 - 1.2 9.1 0.0 3.1 7.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) ABC_membrane_2 PF06472.10 EON99370.1 - 1.4e-109 365.6 1.2 1.4e-109 365.6 0.8 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EON99370.1 - 8.7e-18 64.9 0.0 1.8e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EON99370.1 - 0.00072 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EON99370.1 - 0.0077 16.2 1.1 0.046 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EON99370.1 - 0.034 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EON99370.1 - 0.055 13.8 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EON99370.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 EON99370.1 - 0.083 12.1 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 EON99370.1 - 0.093 11.8 0.1 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Glyco_hydro_72 PF03198.9 EON99371.1 - 1.4e-115 385.6 0.0 1.7e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EON99371.1 - 0.031 13.4 0.0 0.16 11.1 0.0 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Aldose_epim PF01263.15 EON99372.1 - 2.9e-45 154.6 0.1 3.9e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase GDPD PF03009.12 EON99373.1 - 3.3e-67 226.6 0.0 6.5e-67 225.7 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EON99373.1 - 1.4e-32 111.8 0.0 2.2e-12 47.1 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EON99373.1 - 2.1e-32 110.9 0.4 2.5e-11 43.7 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 EON99373.1 - 1.4e-29 103.7 3.3 1.1e-16 61.4 0.9 3.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EON99373.1 - 5.1e-29 98.6 0.5 2e-07 30.4 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EON99373.1 - 1.5e-25 88.6 1.1 1.4e-08 34.7 0.1 5.8 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON99373.1 - 1.2e-16 59.1 0.6 0.00054 19.9 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.2 EON99374.1 - 4.9e-40 135.7 1.6 1.9e-14 53.7 0.1 4.1 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EON99374.1 - 7.5e-34 115.5 12.2 9.8e-12 45.0 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 EON99374.1 - 1.7e-30 103.3 13.0 2.7e-06 26.9 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 EON99374.1 - 2.7e-24 84.6 11.8 5.7e-05 23.2 0.1 7.8 3 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON99374.1 - 1.5e-22 77.4 6.6 0.00076 19.4 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.14 EON99374.1 - 4.6e-16 59.4 8.8 1.2e-12 48.1 1.1 2.1 1 1 1 2 2 2 2 SPX domain GDPD PF03009.12 EON99374.1 - 3.3e-07 30.0 0.0 3.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SLAC1 PF03595.12 EON99375.1 - 3.1e-40 137.8 18.1 2.2e-20 72.5 2.5 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF2838 PF10998.3 EON99375.1 - 7.4 6.5 8.7 0.46 10.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Pro_isomerase PF00160.16 EON99378.1 - 4e-42 144.0 0.0 4.6e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.15 EON99379.1 - 7.6e-17 60.6 0.0 9.7e-17 60.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF4131 PF13567.1 EON99380.1 - 0.8 9.0 4.2 10 5.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Meth_synt_2 PF01717.13 EON99381.1 - 4.1e-147 489.3 0.0 2.8e-140 466.8 0.0 2.7 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EON99381.1 - 8.2e-124 412.9 0.0 6.9e-111 370.4 0.0 3.4 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EON99381.1 - 0.00081 18.4 0.0 0.097 11.5 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) ADH_zinc_N PF00107.21 EON99382.1 - 2.3e-28 98.3 0.0 3.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON99382.1 - 4.5e-13 50.2 0.1 1.4e-12 48.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON99382.1 - 4.6e-12 45.6 0.0 8.8e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EON99382.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 EON99382.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF972 PF06156.8 EON99383.1 - 0.015 15.6 7.0 0.015 15.6 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ERM PF00769.14 EON99383.1 - 0.089 12.3 26.2 0.15 11.5 18.2 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Arfaptin PF06456.8 EON99383.1 - 0.18 11.1 7.2 0.36 10.1 5.0 1.4 1 0 0 1 1 1 0 Arfaptin-like domain Tropomyosin_1 PF12718.2 EON99383.1 - 0.24 11.2 22.4 0.061 13.1 8.5 2.6 1 1 1 2 2 2 0 Tropomyosin like Tropomyosin PF00261.15 EON99383.1 - 0.26 10.3 20.1 0.13 11.3 8.0 2.3 2 0 0 2 2 2 0 Tropomyosin IFT57 PF10498.4 EON99383.1 - 0.37 9.4 14.9 0.61 8.7 10.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.1 EON99383.1 - 0.45 9.6 18.7 1.6 7.8 13.0 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.1 EON99383.1 - 0.59 9.5 23.0 1.3 8.3 16.0 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.4 EON99383.1 - 0.63 8.2 23.3 0.86 7.8 16.1 1.2 1 0 0 1 1 1 0 Transmembrane protein FH2 PF02181.18 EON99383.1 - 1 8.1 11.5 4.3 6.1 5.2 2.3 2 1 0 2 2 2 0 Formin Homology 2 Domain V_ATPase_I PF01496.14 EON99383.1 - 1.6 6.4 14.1 1.3 6.7 8.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EON99383.1 - 1.8 8.5 16.6 0.14 12.0 4.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 EON99383.1 - 3.7 7.6 21.9 0.14 12.2 5.4 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EON99383.1 - 4.1 5.9 16.6 0.97 8.0 8.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.9 EON99383.1 - 4.4 6.5 31.8 8.6 5.5 18.0 2.7 1 1 1 3 3 3 0 Laminin Domain I Prominin PF05478.6 EON99383.1 - 6 4.2 16.4 7.8 3.8 11.4 1.1 1 0 0 1 1 1 0 Prominin TBPIP PF07106.8 EON99383.1 - 9.5 5.7 12.7 3.1 7.3 5.3 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3287 PF11690.3 EON99383.1 - 9.6 6.3 11.5 2.1 8.4 2.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) Diphthamide_syn PF01866.12 EON99384.1 - 9.6e-73 245.0 0.0 1.2e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Metallophos_2 PF12850.2 EON99385.1 - 1.1e-13 51.2 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EON99385.1 - 0.098 12.0 0.1 0.82 9.0 0.0 2.0 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase GCN5L1 PF06320.8 EON99386.1 - 1.6e-10 40.8 1.1 2.5e-10 40.2 0.8 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) SPX PF03105.14 EON99386.1 - 0.0054 16.5 0.4 0.0072 16.1 0.3 1.3 1 0 0 1 1 1 1 SPX domain Serglycin PF04360.7 EON99386.1 - 0.026 14.2 0.1 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Serglycin CR6_interact PF10147.4 EON99386.1 - 0.083 12.1 0.7 0.14 11.4 0.5 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 HAUS6_N PF14661.1 EON99386.1 - 0.23 10.8 1.7 0.35 10.1 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PITH PF06201.8 EON99387.1 - 1.8e-50 170.6 0.1 2.2e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.17 EON99388.1 - 1.9e-34 119.2 1.9 6.4e-33 114.2 1.3 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 NUDIX PF00293.23 EON99389.1 - 6.9e-16 58.1 0.8 8.5e-16 57.8 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4563 PF15124.1 EON99389.1 - 0.0037 16.8 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4563) DUF4123 PF13503.1 EON99389.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4123) adh_short PF00106.20 EON99390.1 - 1.5e-16 60.7 0.0 2.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99390.1 - 8.3e-09 35.3 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EON99390.1 - 0.00018 21.3 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EON99390.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EON99390.1 - 0.12 11.2 0.1 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Coa1 PF08695.5 EON99391.1 - 2e-40 136.9 0.0 2.5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ketoacyl-synt PF00109.21 EON99392.1 - 2.8e-63 213.7 0.3 7.5e-63 212.3 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EON99392.1 - 4.6e-33 114.8 1.3 8.5e-33 114.0 0.9 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EON99392.1 - 4e-31 107.3 0.0 9.2e-31 106.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EON99392.1 - 3.1e-29 101.6 0.0 5.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EON99392.1 - 4.7e-11 43.0 0.0 1.6e-10 41.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EON99392.1 - 1.8e-10 40.6 0.1 8.6e-10 38.4 0.0 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EON99392.1 - 1.5e-09 37.9 0.6 3.8e-09 36.6 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EON99392.1 - 6.4e-07 29.2 0.0 2.2e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99392.1 - 1.6e-06 27.7 0.0 4.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EON99392.1 - 1.2e-05 25.3 0.1 6.5e-05 22.9 0.1 2.4 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.1 EON99392.1 - 1.7e-05 25.1 0.0 9.7e-05 22.6 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON99392.1 - 5.4e-05 23.6 0.0 0.00028 21.3 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EON99392.1 - 0.00021 20.3 0.0 0.00063 18.7 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 EON99392.1 - 0.00025 20.7 0.0 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 1 KR domain Methyltransf_28 PF02636.12 EON99392.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DapB_N PF01113.15 EON99392.1 - 0.029 14.3 0.2 0.15 11.9 0.0 2.4 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EON99392.1 - 0.046 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EON99392.1 - 0.29 9.7 0.1 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_2 PF07719.12 EON99394.1 - 1.6e-11 43.2 9.1 0.00039 20.1 0.8 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EON99394.1 - 5.1e-11 42.0 0.4 5.1e-11 42.0 0.3 5.0 6 0 0 6 6 6 1 TPR repeat TPR_1 PF00515.23 EON99394.1 - 1e-10 40.7 0.4 0.00031 20.2 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON99394.1 - 4.6e-10 39.8 4.3 5.8e-10 39.5 0.3 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EON99394.1 - 6.3e-08 31.8 0.6 0.021 14.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EON99394.1 - 1.1e-07 31.6 4.1 3.6e-06 26.8 0.3 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EON99394.1 - 4.9e-06 26.7 0.5 0.0006 20.2 0.1 5.1 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EON99394.1 - 5.6e-06 25.7 0.9 0.17 11.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EON99394.1 - 7.7e-05 22.9 0.2 0.016 15.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EON99394.1 - 0.002 17.9 0.1 0.0091 15.8 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EON99394.1 - 0.05 14.0 0.7 21 5.8 0.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LIP PF03583.9 EON99395.1 - 1.5e-61 208.1 0.2 2e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase FYVE PF01363.16 EON99396.1 - 1.2e-22 79.5 20.3 1.1e-16 60.5 4.1 2.3 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.3 EON99396.1 - 6.3e-06 25.6 0.3 2e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 EON99396.1 - 0.0003 20.5 2.5 0.0003 20.5 1.7 3.6 4 1 1 5 5 4 1 AN1-like Zinc finger Seryl_tRNA_N PF02403.17 EON99396.1 - 0.0089 16.0 3.4 0.0098 15.8 0.5 2.3 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF3719 PF12516.3 EON99396.1 - 0.057 12.9 0.3 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) C6_DPF PF10170.4 EON99396.1 - 0.09 12.8 3.5 0.13 12.2 0.1 3.0 3 1 0 3 3 3 0 Cysteine-rich domain TMF_DNA_bd PF12329.3 EON99396.1 - 0.24 11.2 5.6 3 7.6 0.2 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 EON99396.1 - 0.33 10.6 4.3 8.7 6.1 0.2 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 EON99396.1 - 0.71 9.8 0.0 0.71 9.8 0.0 3.8 4 0 0 4 4 4 0 bZIP transcription factor HypA PF01155.14 EON99396.1 - 2.1 8.0 9.3 1.3 8.7 0.2 3.0 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EON99396.1 - 3.7 7.4 13.2 0.69 9.8 0.5 3.6 3 0 0 3 3 3 0 FYVE-type zinc finger Shugoshin_N PF07558.6 EON99396.1 - 6.9 6.4 6.7 11 5.8 0.2 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region zf-DHHC PF01529.15 EON99396.1 - 8.6 5.7 11.4 1.2 8.4 0.7 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Sugar_tr PF00083.19 EON99397.1 - 3.8e-67 226.8 26.6 4.3e-67 226.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99397.1 - 6e-16 58.0 32.8 1.5e-15 56.7 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraP PF07296.6 EON99397.1 - 0.001 18.1 0.0 0.0026 16.7 0.0 1.6 1 0 0 1 1 1 1 TraP protein MFS_1 PF07690.11 EON99398.1 - 5.8e-27 94.3 25.7 1.3e-15 57.0 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_4 PF13637.1 EON99399.1 - 3.9e-16 59.0 1.9 1.2e-09 38.4 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON99399.1 - 1.2e-13 50.7 0.8 9.7e-05 22.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EON99399.1 - 1.3e-12 47.9 0.5 1.9e-05 24.9 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EON99399.1 - 4.2e-10 38.9 3.0 0.0021 17.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EON99399.1 - 4.2e-10 38.8 1.0 0.011 15.8 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EON99399.1 - 4.1e-05 23.1 0.7 0.00029 20.4 0.5 2.5 1 1 0 1 1 1 1 KilA-N domain NPV_P10 PF05531.7 EON99399.1 - 0.078 13.2 4.8 4.2 7.6 0.9 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EON99399.1 - 0.15 11.5 7.7 4.1 6.7 3.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein FliJ PF02050.11 EON99399.1 - 0.29 11.1 8.7 1.2 9.2 4.0 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein Fez1 PF06818.10 EON99399.1 - 0.42 10.6 10.8 1.7 8.6 7.5 1.9 1 1 0 1 1 1 0 Fez1 ADIP PF11559.3 EON99399.1 - 1.6 8.5 11.7 13 5.6 5.1 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EON99399.1 - 3.8 7.6 7.0 4.2 7.4 3.5 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Aa_trans PF01490.13 EON99400.1 - 2.5e-29 102.0 34.6 2.9e-29 101.7 24.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.19 EON99401.1 - 4.8e-67 226.5 12.7 5.4e-67 226.3 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Proteasome PF00227.21 EON99402.1 - 7.2e-27 93.8 0.1 8.3e-27 93.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Acetyltransf_1 PF00583.19 EON99403.1 - 9.6e-14 51.1 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EON99403.1 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EON99403.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EON99403.1 - 0.00059 19.9 0.0 0.0014 18.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EON99403.1 - 0.00064 19.9 0.0 0.0021 18.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EON99403.1 - 0.021 14.7 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EON99404.1 - 7.7e-62 209.3 0.0 1.4e-61 208.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 adh_short PF00106.20 EON99405.1 - 0.0046 16.8 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Complex1_LYR_1 PF13232.1 EON99407.1 - 2.1e-07 31.0 1.6 5.2e-07 29.7 1.1 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EON99407.1 - 2.3e-07 30.5 3.2 5.9e-07 29.1 2.2 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Sirohm_synth_C PF14823.1 EON99408.1 - 2.6e-24 84.2 0.0 3.9e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EON99408.1 - 1e-23 83.5 0.0 1.6e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EON99408.1 - 5.9e-14 50.7 0.1 1.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 EON99408.1 - 0.0089 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family 5_nucleotid_C PF02872.13 EON99409.1 - 5.1e-36 123.9 0.0 8.7e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EON99409.1 - 0.00013 21.4 0.1 0.00029 20.2 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4387 PF14330.1 EON99410.1 - 7.6e-32 109.5 0.0 1.4e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EON99410.1 - 3.3e-07 29.1 0.1 1.9e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) FAD_binding_3 PF01494.14 EON99411.1 - 3.2e-10 39.5 0.1 0.0038 16.3 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 EON99411.1 - 9.1e-06 24.7 0.2 2.4e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EON99411.1 - 9.1e-06 24.7 0.2 1.6e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EON99411.1 - 2.3e-05 24.2 0.4 8.2e-05 22.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON99411.1 - 0.00019 21.3 0.1 0.00038 20.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON99411.1 - 0.0011 17.9 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON99411.1 - 0.0016 17.0 0.2 0.0052 15.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EON99411.1 - 0.0021 18.1 0.1 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EON99411.1 - 0.014 14.4 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON99411.1 - 0.028 13.3 0.1 0.17 10.8 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EON99411.1 - 0.037 14.4 1.1 0.092 13.1 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EON99411.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EON99413.1 - 4.1e-25 87.8 0.0 7.3e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON99413.1 - 4.4e-07 30.8 0.0 2.4e-06 28.4 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EON99413.1 - 0.093 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EON99414.1 - 1.2e-23 83.8 0.4 1.9e-23 83.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99414.1 - 5.7e-15 55.7 0.0 8.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99414.1 - 9.2e-07 28.6 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EON99414.1 - 1.4e-05 25.1 0.1 2.5e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON99414.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EON99414.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MFS_1 PF07690.11 EON99415.1 - 3.2e-17 62.2 16.1 4.5e-17 61.7 11.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 EON99416.1 - 4.8e-20 72.4 3.6 4.8e-10 39.6 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 EON99416.1 - 5e-19 69.4 8.9 1.2e-17 64.8 6.1 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EON99416.1 - 7.6e-12 44.8 0.1 2.1e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EON99416.1 - 1.3e-06 27.9 5.1 0.0017 17.6 1.7 2.6 2 1 0 2 2 2 2 Amidohydrolase family Cpn60_TCP1 PF00118.19 EON99417.1 - 9.4e-133 443.3 9.9 1.1e-132 443.1 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EON99417.1 - 0.12 12.6 0.4 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Peptidase_S28 PF05577.7 EON99418.1 - 0.00033 19.3 0.1 0.0034 16.0 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 CVNH PF08881.5 EON99419.1 - 3.3e-13 49.7 0.0 7.4e-13 48.6 0.0 1.5 1 1 1 2 2 2 2 CVNH domain FA_desaturase PF00487.19 EON99420.1 - 2.6e-23 82.7 18.3 4e-23 82.1 12.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EON99420.1 - 6.6e-08 32.6 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) eIF2A PF08662.6 EON99421.1 - 4.1e-39 134.2 4.3 7.1e-38 130.2 0.3 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EON99421.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EON99421.1 - 0.00015 21.2 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99421.1 - 0.00017 21.4 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EON99421.1 - 0.0017 18.1 0.7 1.6 8.7 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Prenyltrans PF00432.16 EON99422.1 - 5.1e-32 109.1 15.0 2.3e-06 27.0 0.0 6.9 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EON99422.1 - 2.5e-20 72.9 0.0 7.8e-11 42.3 0.0 3.8 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EON99422.1 - 3.3e-05 23.8 0.0 0.0019 18.2 0.0 3.3 3 1 0 3 3 3 1 Prenyltransferase-like Ilm1 PF10311.4 EON99423.1 - 5.4e-60 201.6 0.5 6.2e-60 201.4 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4345 PF14248.1 EON99423.1 - 0.3 10.5 6.2 4.1 6.8 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4345) Pkinase PF00069.20 EON99424.1 - 5.6e-53 179.7 0.3 7.5e-53 179.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99424.1 - 1.8e-29 102.6 0.0 2.4e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON99424.1 - 9.5e-09 34.6 0.0 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON99424.1 - 0.00049 19.9 0.8 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EON99424.1 - 0.0011 18.0 0.2 0.0035 16.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EON99424.1 - 0.035 13.4 0.0 0.035 13.4 0.0 2.0 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.15 EON99424.1 - 0.069 12.7 0.2 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase U1snRNP70_N PF12220.3 EON99424.1 - 0.075 13.3 1.1 0.17 12.1 0.7 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal IF-2B PF01008.12 EON99425.1 - 5.2e-71 238.9 0.5 6.2e-71 238.6 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RabGAP-TBC PF00566.13 EON99426.1 - 9.6e-20 70.9 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NatB_MDM20 PF09797.4 EON99427.1 - 7e-43 146.7 0.0 1.6e-22 79.7 0.0 3.4 2 1 1 3 3 3 3 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_M20 PF01546.23 EON99428.1 - 3.2e-22 78.9 0.1 6.5e-22 77.9 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON99428.1 - 2.6e-17 62.5 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EON99428.1 - 0.032 13.9 0.1 0.078 12.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_M35 PF02102.10 EON99430.1 - 1.2e-91 307.0 19.1 1.4e-91 306.8 13.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EON99430.1 - 7e-05 23.3 2.6 0.00012 22.5 1.8 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Potyvirid-P3 PF13608.1 EON99430.1 - 0.033 13.3 1.7 0.045 12.8 1.2 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein CARDB PF07705.6 EON99430.1 - 0.036 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 CARDB Borrelia_P83 PF05262.6 EON99431.1 - 1 7.5 38.7 1.3 7.1 26.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 EON99433.1 - 8 5.7 40.1 10 5.4 27.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EON99433.1 - 9.5 4.3 27.0 13 3.9 18.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FAD_binding_3 PF01494.14 EON99435.1 - 9.7e-26 90.6 0.0 2.1e-25 89.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SnoaL PF07366.7 EON99435.1 - 1.7e-10 40.5 0.0 1.5e-09 37.5 0.1 2.5 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EON99435.1 - 3.4e-10 40.2 0.3 1e-09 38.6 0.2 1.9 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_8 PF13450.1 EON99435.1 - 1.3e-08 34.6 0.6 3.4e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EON99435.1 - 1.1e-07 31.2 0.1 0.0054 15.8 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EON99435.1 - 0.00012 21.0 1.6 0.0002 20.3 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON99435.1 - 0.00013 21.0 0.6 0.0003 19.8 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EON99435.1 - 0.00088 18.2 0.1 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EON99435.1 - 0.0011 18.8 0.4 0.0025 17.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99435.1 - 0.0024 17.9 0.0 0.0055 16.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EON99435.1 - 0.0072 14.8 0.1 0.013 14.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EON99435.1 - 0.023 13.5 0.3 0.033 13.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EON99435.1 - 0.024 13.7 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family IlvN PF07991.7 EON99435.1 - 0.039 13.3 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EON99435.1 - 0.048 13.4 0.6 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EON99435.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EON99435.1 - 0.13 12.7 0.2 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SAMP PF05924.6 EON99435.1 - 0.19 10.9 0.4 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 SAMP Motif FAD_oxidored PF12831.2 EON99435.1 - 0.19 10.7 0.5 0.31 10.0 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase APH PF01636.18 EON99437.1 - 1.1e-11 44.9 1.2 1.4e-11 44.6 0.9 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EON99437.1 - 7e-05 22.4 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.1 EON99438.1 - 1.1e-17 64.4 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.11 EON99440.1 - 1.7e-18 66.4 12.1 1.7e-18 66.4 8.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmD PF04995.9 EON99440.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RRM_1 PF00076.17 EON99441.1 - 5.4e-25 86.8 0.3 3.2e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99441.1 - 5.4e-16 58.3 0.0 7e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99441.1 - 1.8e-06 27.6 0.2 0.041 13.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EON99441.1 - 9e-05 22.1 0.1 0.043 13.5 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EON99441.1 - 0.00053 19.2 0.0 0.0016 17.7 0.0 1.9 1 0 0 1 1 1 1 Lsm interaction motif Fasciclin PF02469.17 EON99442.1 - 2.8e-38 130.7 0.0 2e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain WD40 PF00400.27 EON99443.1 - 1.8e-61 201.9 25.2 4.5e-11 42.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EON99443.1 - 0.00016 19.9 6.5 0.24 9.4 0.1 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EON99443.1 - 0.043 12.1 0.0 4.3 5.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain MR_MLE_C PF13378.1 EON99444.1 - 8.9e-21 73.9 0.0 2.6e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EON99444.1 - 9.5e-13 48.4 0.0 2.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EON99444.1 - 9.5e-10 38.5 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidase PF01425.16 EON99445.1 - 3.2e-63 214.1 0.4 2e-61 208.2 0.0 2.1 2 0 0 2 2 2 2 Amidase Aldo_ket_red PF00248.16 EON99445.1 - 1.2e-44 152.2 0.0 1.9e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 EON99447.1 - 1e-18 67.4 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH_6_hur PF04655.9 EON99447.1 - 0.049 12.7 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DUF2726 PF10881.3 EON99447.1 - 0.14 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) HA2 PF04408.18 EON99449.1 - 6.8e-19 67.7 0.0 2.1e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EON99449.1 - 3.7e-12 45.9 0.0 8.6e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EON99449.1 - 1.8e-11 43.8 0.0 3.2e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EON99449.1 - 1.5e-08 34.8 1.7 2e-07 31.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.11 EON99449.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold NB-ARC PF00931.17 EON99449.1 - 0.0037 16.1 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 EON99449.1 - 0.0084 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EON99449.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EON99449.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EON99449.1 - 0.025 14.4 0.5 1.1 9.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EON99449.1 - 0.15 11.2 0.0 0.42 9.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Amidohydro_4 PF13147.1 EON99450.1 - 2.6e-27 96.5 9.6 1.6e-25 90.7 6.7 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EON99450.1 - 1.5e-21 77.3 1.0 4e-21 76.0 0.7 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EON99450.1 - 6.3e-12 45.1 1.3 3.1e-11 42.9 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EON99450.1 - 5.4e-11 42.3 13.6 2.9e-09 36.6 5.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family NTP_transf_3 PF12804.2 EON99450.1 - 0.0081 16.2 0.4 0.037 14.1 0.3 2.1 1 1 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.11 EON99451.1 - 1.8e-40 138.7 32.0 1.8e-40 138.7 22.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EON99451.1 - 0.00033 18.8 3.0 0.00053 18.2 2.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector NIT PF08376.5 EON99452.1 - 0.0029 17.1 0.0 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 Nitrate and nitrite sensing TMEM61 PF15105.1 EON99452.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM61 protein family DUF4239 PF14023.1 EON99452.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Fungal_trans PF04082.13 EON99453.1 - 3.6e-17 62.0 0.1 4.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SHMT PF00464.14 EON99455.1 - 1.7e-190 632.6 0.0 2.2e-190 632.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EON99455.1 - 0.0026 16.9 0.0 0.0049 16.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase 2OG-FeII_Oxy_2 PF13532.1 EON99456.1 - 6e-25 88.2 0.1 1.4e-24 86.9 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EON99456.1 - 4.1e-23 82.1 0.0 1.5e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.27 EON99457.1 - 1.3e-42 142.1 10.1 1.4e-07 31.0 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EON99457.1 - 0.0015 17.3 0.8 1.7 7.3 0.0 3.0 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EON99457.1 - 0.011 15.1 0.1 1.5 8.2 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain SGL PF08450.7 EON99457.1 - 0.08 12.3 0.2 0.27 10.5 0.1 1.8 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Ribosomal_L19e PF01280.15 EON99459.1 - 4.6e-60 201.6 7.1 4.6e-60 201.6 4.9 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e TRAPP PF04051.11 EON99461.1 - 6.8e-36 123.0 0.0 8.3e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CUB PF00431.15 EON99461.1 - 0.029 14.4 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 CUB domain Ribosomal_L22 PF00237.14 EON99462.1 - 1.3e-17 63.5 0.1 4.5e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e HEAT_2 PF13646.1 EON99463.1 - 3.1e-43 145.9 59.4 4.6e-10 39.6 0.1 17.0 10 3 7 17 17 17 11 HEAT repeats HEAT PF02985.17 EON99463.1 - 1e-39 131.0 36.1 0.0055 16.6 0.0 23.2 25 0 0 25 25 24 9 HEAT repeat HEAT_EZ PF13513.1 EON99463.1 - 9.4e-35 118.2 65.6 1.9e-06 28.1 0.0 24.1 18 5 7 25 25 24 10 HEAT-like repeat DUF3554 PF12074.3 EON99463.1 - 1.3e-34 120.1 10.9 2.5e-24 86.3 0.2 5.5 5 1 1 6 6 6 2 Domain of unknown function (DUF3554) Vac14_Fab1_bd PF12755.2 EON99463.1 - 1.6e-16 60.4 0.0 0.99 9.8 0.0 9.7 7 3 1 9 9 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EON99463.1 - 2.3e-15 56.5 0.0 0.0036 16.6 0.0 6.8 4 2 1 6 6 6 3 CLASP N terminal ParcG PF10274.4 EON99463.1 - 3.2e-15 56.5 1.6 5.6e-05 23.1 0.0 6.6 6 1 0 6 6 6 3 Parkin co-regulated protein Cnd1 PF12717.2 EON99463.1 - 3e-12 46.7 3.7 1.2 8.9 0.0 8.9 7 3 2 10 10 10 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EON99463.1 - 1.8e-09 37.4 0.3 10 6.1 0.0 8.1 6 2 4 10 10 10 2 UME (NUC010) domain Ipi1_N PF12333.3 EON99463.1 - 9.6e-07 28.7 0.4 0.022 14.7 0.0 6.9 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 EON99463.1 - 0.063 12.0 19.4 0.22 10.2 0.3 7.1 6 2 2 8 8 8 0 RNAPII transcription regulator C-terminal Oxidored_FMN PF00724.15 EON99465.1 - 2.6e-43 148.3 0.0 3.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TPP_enzyme_N PF02776.13 EON99468.1 - 4.5e-44 149.9 2.5 1e-43 148.7 1.7 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EON99468.1 - 1e-40 138.7 0.2 2.9e-39 134.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EON99468.1 - 1e-21 77.1 0.0 2.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EON99468.1 - 0.0021 17.5 1.1 0.0034 16.9 0.8 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase PF00069.20 EON99469.1 - 9.9e-19 67.4 0.0 5.7e-18 64.9 0.0 1.9 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99469.1 - 3.2e-18 65.7 0.0 3.1e-16 59.2 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.1 EON99469.1 - 1.1e-16 60.3 3.5 1.6e-08 34.1 0.8 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EON99469.1 - 5.6e-16 57.7 0.3 0.00065 19.2 0.0 5.2 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EON99469.1 - 2.9e-10 38.7 1.0 0.3 11.2 0.0 6.3 7 0 0 7 7 6 2 Leucine Rich Repeat Kdo PF06293.9 EON99469.1 - 8.1e-06 25.0 0.2 2.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_7 PF13504.1 EON99469.1 - 0.00016 21.2 7.7 4.3 7.9 0.1 5.9 6 0 0 6 6 5 1 Leucine rich repeat APH PF01636.18 EON99469.1 - 0.0011 18.7 0.1 0.0043 16.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EON99469.1 - 0.0013 18.1 0.0 0.0031 16.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EON99469.1 - 0.0046 15.9 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.1 EON99469.1 - 0.14 12.2 2.1 40 4.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat ADH_N PF08240.7 EON99470.1 - 4.5e-19 68.2 1.1 1.5e-18 66.5 0.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EON99470.1 - 7.3e-11 41.5 0.5 7.3e-11 41.5 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EON99470.1 - 0.00025 20.5 0.0 0.005 16.3 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_16 PF00722.16 EON99471.1 - 1.3e-19 70.2 0.2 1.8e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EON99471.1 - 1.3e-09 36.7 0.1 2.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DNA_gyraseB PF00204.20 EON99471.1 - 0.043 13.0 0.1 0.68 9.1 0.0 2.3 3 0 0 3 3 3 0 DNA gyrase B DUF2401 PF10287.4 EON99471.1 - 0.08 12.4 0.7 0.21 11.0 0.5 1.8 1 1 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Bromo_TP PF07524.8 EON99472.1 - 1.5e-15 56.6 0.1 3.1e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EON99472.1 - 5.2e-10 39.2 7.2 1.7e-05 24.7 1.2 2.8 1 1 1 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term adh_short PF00106.20 EON99473.1 - 1.5e-24 86.7 0.1 2.1e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99473.1 - 1.7e-18 67.3 0.0 2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99473.1 - 2.4e-08 33.8 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EON99473.1 - 0.048 12.5 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 EON99474.1 - 2.9e-31 108.4 41.1 2.9e-31 108.4 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EON99474.1 - 0.044 13.5 6.3 0.19 11.5 1.0 3.4 3 0 0 3 3 3 0 MFS_1 like family MFS_1 PF07690.11 EON99475.1 - 3.6e-34 118.0 31.5 4.8e-34 117.6 21.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EON99475.1 - 0.047 14.0 0.2 0.17 12.2 0.1 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MAPEG PF01124.13 EON99475.1 - 4.4 6.9 12.3 2.2 7.9 5.0 2.7 2 1 0 2 2 2 0 MAPEG family LisH PF08513.6 EON99476.1 - 0.24 11.2 1.5 0.48 10.2 1.0 1.5 1 0 0 1 1 1 0 LisH Ribosomal_L32p PF01783.18 EON99476.1 - 1.9 8.7 8.6 0.2 11.8 2.2 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family Methyltransf_12 PF08242.7 EON99477.1 - 0.014 15.8 0.2 0.017 15.5 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF1996 PF09362.5 EON99478.1 - 2.6e-32 112.3 2.3 1e-22 80.9 0.3 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) zf-CCHC PF00098.18 EON99479.1 - 5.4e-44 146.0 58.3 4e-08 32.8 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EON99479.1 - 7.7e-10 38.2 41.0 0.073 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EON99479.1 - 1.6e-05 24.5 42.8 0.064 12.9 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EON99479.1 - 0.044 13.4 0.2 0.044 13.4 0.1 6.8 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 EON99479.1 - 0.079 12.4 0.4 0.079 12.4 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle Hydrolase_6 PF13344.1 EON99480.1 - 6.3e-23 80.5 0.0 1.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EON99480.1 - 1.3e-11 43.9 0.0 1.4e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EON99480.1 - 0.0086 16.5 0.0 0.21 11.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EON99480.1 - 0.014 15.6 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1237 PF06824.6 EON99481.1 - 1.5e-163 544.3 0.1 1.9e-163 543.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Big_3_4 PF13754.1 EON99482.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Peptidase_M20 PF01546.23 EON99483.1 - 2.9e-07 30.1 0.2 4.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EON99483.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Topo_Zn_Ribbon PF08272.6 EON99483.1 - 0.12 11.7 0.2 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Arginase PF00491.16 EON99485.1 - 2e-82 276.6 0.5 2.6e-82 276.2 0.3 1.1 1 0 0 1 1 1 1 Arginase family ABM PF03992.11 EON99487.1 - 0.00065 19.6 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AA_permease_2 PF13520.1 EON99488.1 - 1.1e-59 202.1 52.2 1.3e-59 201.8 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EON99488.1 - 5.3e-19 67.9 46.3 7.2e-19 67.4 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_S29 PF02907.10 EON99489.1 - 0.0026 17.2 0.1 0.0052 16.3 0.1 1.5 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S64 PF08192.6 EON99489.1 - 0.019 13.2 1.1 0.04 12.2 0.0 1.9 2 1 1 3 3 3 0 Peptidase family S64 C_GCAxxG_C_C PF09719.5 EON99490.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) HNF-1_N PF04814.8 EON99490.1 - 0.099 12.7 1.0 5.4 7.0 0.5 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Arginase PF00491.16 EON99492.1 - 1.6e-63 214.6 0.2 1.7e-63 214.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EON99492.1 - 0.053 13.7 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SDH_alpha PF03313.10 EON99495.1 - 0.0017 17.4 0.2 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain zf-C3HC4_2 PF13923.1 EON99496.1 - 1.5e-07 31.2 9.4 2.7e-07 30.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON99496.1 - 1.8e-07 30.7 3.9 2.9e-07 30.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EON99496.1 - 1.8e-07 30.6 2.4 3.3e-07 29.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EON99496.1 - 2.7e-06 27.0 6.4 4.6e-06 26.2 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EON99496.1 - 3.3e-06 26.6 7.7 6e-06 25.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EON99496.1 - 5.3e-05 22.9 6.0 8.6e-05 22.2 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain Harakiri PF15196.1 EON99496.1 - 0.025 14.7 1.0 0.06 13.5 0.7 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri zf-C3HC4_4 PF15227.1 EON99496.1 - 0.24 11.2 7.8 0.57 10.0 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cript PF10235.4 EON99496.1 - 0.78 10.1 4.5 0.28 11.5 0.7 2.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-RING_UBOX PF13445.1 EON99496.1 - 1.9 8.2 7.2 0.26 11.0 1.9 1.9 2 0 0 2 2 2 0 RING-type zinc-finger p450 PF00067.17 EON99497.1 - 1.8e-53 181.7 0.0 2.3e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EON99498.1 - 1.8e-21 76.4 0.0 5e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99498.1 - 1.1e-06 27.9 0.0 3.8e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase HisKA_3 PF07730.8 EON99499.1 - 1.6 9.1 6.6 0.15 12.4 0.4 2.3 2 0 0 2 2 2 0 Histidine kinase IIGP PF05049.8 EON99500.1 - 1.6e-17 63.4 0.2 2.4e-17 62.8 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EON99500.1 - 9e-07 28.8 0.0 2.5e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EON99500.1 - 0.015 15.1 10.0 0.1 12.4 0.8 3.2 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 EON99500.1 - 0.053 13.8 1.4 0.39 10.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter Miro PF08477.8 EON99500.1 - 0.063 13.7 2.0 0.094 13.2 0.0 2.3 3 0 0 3 3 3 0 Miro-like protein Peptidase_S49_N PF08496.5 EON99500.1 - 0.49 10.1 13.4 0.12 12.1 5.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PA26 PF04636.8 EON99500.1 - 4.6 5.8 10.1 0.9 8.1 4.4 1.6 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) NAD_binding_9 PF13454.1 EON99504.1 - 0.00038 20.2 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EON99504.1 - 0.00044 20.1 0.0 0.0028 17.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON99504.1 - 0.0022 16.9 0.4 0.0037 16.2 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EON99504.1 - 0.0083 14.6 0.0 0.021 13.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EON99504.1 - 0.0085 16.1 0.2 0.021 14.9 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EON99505.1 - 6.4e-22 77.6 0.0 2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EON99505.1 - 5e-16 59.1 6.9 1.2e-14 54.7 4.8 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON99505.1 - 6.3e-16 58.5 3.3 7.3e-16 58.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EON99505.1 - 1.4e-06 28.1 1.0 4.8e-05 23.0 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EON99505.1 - 1.4e-05 25.2 0.1 0.0012 18.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON99505.1 - 3.9e-05 22.6 4.6 0.031 13.1 0.1 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 EON99505.1 - 0.00014 20.4 6.7 0.037 12.5 0.0 3.0 2 1 1 3 3 3 2 HI0933-like protein DAO PF01266.19 EON99505.1 - 0.00021 20.3 9.2 0.11 11.3 0.1 3.9 5 0 0 5 5 5 3 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EON99505.1 - 0.0013 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EON99505.1 - 0.0018 17.2 2.3 1.5 7.6 0.1 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein XdhC_C PF13478.1 EON99505.1 - 0.004 17.4 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 EON99505.1 - 0.011 16.0 0.5 0.03 14.5 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 EON99505.1 - 0.019 14.0 0.8 3.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EON99505.1 - 0.03 14.3 1.8 3.2 7.8 0.3 3.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.12 EON99505.1 - 0.031 14.7 1.6 0.35 11.3 0.1 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EON99505.1 - 0.058 12.7 0.2 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EON99505.1 - 0.32 10.7 3.9 0.38 10.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EON99505.1 - 1.2 7.8 7.5 0.28 9.9 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain NACHT PF05729.7 EON99506.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UCH_1 PF13423.1 EON99507.1 - 1.2e-64 218.5 0.1 1.2e-44 152.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.17 EON99507.1 - 0.3 10.0 5.1 0.51 9.2 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EON99507.1 - 3.8 6.8 12.8 2 7.7 7.1 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NmrA PF05368.8 EON99508.1 - 2.1e-20 72.9 0.1 2.7e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EON99508.1 - 1.7e-18 67.2 0.4 2.8e-18 66.5 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EON99508.1 - 1.6e-05 24.5 0.1 0.00055 19.4 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EON99508.1 - 0.00013 21.8 0.5 0.00028 20.7 0.3 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EON99508.1 - 0.001 18.1 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EON99508.1 - 0.053 12.2 0.2 0.099 11.3 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EON99508.1 - 0.067 13.2 0.1 0.16 12.0 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EON99508.1 - 0.072 11.9 0.2 0.18 10.6 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EON99508.1 - 0.087 13.1 0.9 0.19 12.0 0.2 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain zf-CCHC PF00098.18 EON99510.1 - 1.3e-11 43.7 9.7 1.8e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EON99510.1 - 5.3e-09 35.5 0.2 1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EON99510.1 - 1.5e-06 27.8 6.3 0.0013 18.4 2.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EON99510.1 - 3.8e-06 26.4 0.2 1e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EON99510.1 - 0.00038 20.0 7.5 0.066 12.8 0.3 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EON99510.1 - 0.00099 18.7 6.0 0.28 10.8 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EON99510.1 - 0.055 12.9 0.2 0.055 12.9 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle Peptidase_M16_C PF05193.16 EON99510.1 - 0.9 9.1 2.8 7.5 6.1 0.0 2.9 3 0 0 3 3 3 0 Peptidase M16 inactive domain FAD_binding_1 PF00667.15 EON99511.1 - 5.9e-43 146.8 0.0 1e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EON99511.1 - 3.9e-10 40.2 0.0 9.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_M28 PF04389.12 EON99512.1 - 5.2e-28 97.9 0.0 8.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 p450 PF00067.17 EON99514.1 - 9.7e-43 146.3 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Med11 PF10280.4 EON99515.1 - 1.3e-32 112.2 0.1 1.5e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein YlqD PF11068.3 EON99517.1 - 0.059 13.4 1.3 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 YlqD protein CytB6-F_Fe-S PF08802.5 EON99517.1 - 3.3 7.7 4.4 3.1 7.8 1.8 1.9 1 1 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit IncA PF04156.9 EON99517.1 - 3.9 7.0 11.4 2.2 7.8 0.8 2.3 2 0 0 2 2 2 0 IncA protein SHOCT PF09851.4 EON99518.1 - 0.0002 20.6 2.5 0.12 11.8 0.1 2.7 2 0 0 2 2 2 2 Short C-terminal domain FACT-Spt16_Nlob PF14826.1 EON99518.1 - 0.22 11.0 6.0 0.17 11.3 0.6 2.4 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain HK97-gp10_like PF04883.7 EON99518.1 - 0.57 11.1 3.0 17 6.4 0.2 3.0 2 1 1 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component GvpL_GvpF PF06386.6 EON99518.1 - 3.5 7.1 7.4 0.38 10.3 0.9 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Nop25 PF09805.4 EON99519.1 - 3.2e-37 127.6 15.1 3.2e-37 127.6 10.5 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ferritin_2 PF13668.1 EON99520.1 - 1.1e-38 132.2 1.4 1.7e-38 131.6 0.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain GMC_oxred_C PF05199.8 EON99521.1 - 6.1e-08 33.0 0.8 4.6e-07 30.2 0.2 2.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EON99521.1 - 4.8e-06 25.9 0.0 3.5e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EON99521.1 - 0.00052 18.9 0.1 0.001 17.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EON99521.1 - 0.014 15.4 0.5 0.043 13.8 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EON99521.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON99521.1 - 0.24 10.2 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 EON99521.1 - 0.25 10.2 2.7 1.6 7.5 0.2 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase DUF410 PF04190.8 EON99522.1 - 2.6e-52 177.9 0.0 3.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RNB PF00773.14 EON99523.1 - 1.2e-76 258.1 0.0 2.8e-76 256.9 0.0 1.7 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 EON99523.1 - 0.041 13.2 0.1 0.091 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) BRCT PF00533.21 EON99525.1 - 0.0001 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Tropomyosin_1 PF12718.2 EON99526.1 - 3.2e-50 169.7 32.8 3.8e-50 169.4 22.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EON99526.1 - 9e-09 34.7 32.7 0.00012 21.2 14.2 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 EON99526.1 - 0.00017 21.4 5.5 0.00017 21.4 3.8 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EON99526.1 - 0.00057 17.7 31.7 0.00068 17.5 22.0 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 EON99526.1 - 0.0033 17.2 27.7 0.024 14.4 6.7 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EON99526.1 - 0.0036 16.0 14.3 0.0036 16.0 9.9 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Cast PF10174.4 EON99526.1 - 0.0063 14.6 27.6 0.0075 14.3 19.2 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone bZIP_1 PF00170.16 EON99526.1 - 0.0072 16.2 29.8 0.24 11.3 1.6 5.0 1 1 3 4 4 4 1 bZIP transcription factor CCDC155 PF14662.1 EON99526.1 - 0.011 15.4 34.0 0.12 12.0 10.0 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 GAS PF13851.1 EON99526.1 - 0.013 14.6 31.3 0.038 13.1 21.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EON99526.1 - 0.014 15.3 30.4 0.014 15.3 6.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EON99526.1 - 0.019 14.0 34.3 0.14 11.1 11.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 EON99526.1 - 0.029 13.9 36.1 0.086 12.3 11.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.4 EON99526.1 - 0.032 14.3 19.5 3.1 8.0 7.2 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 EON99526.1 - 0.041 13.7 25.7 0.85 9.5 11.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3287 PF11690.3 EON99526.1 - 0.044 13.8 0.8 0.044 13.8 0.6 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF4200 PF13863.1 EON99526.1 - 0.052 13.4 34.0 0.58 10.1 10.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 EON99526.1 - 0.057 13.5 17.0 0.63 10.1 3.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EON99526.1 - 0.063 13.0 27.2 0.75 9.5 12.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NABP PF07990.7 EON99526.1 - 0.068 12.4 5.1 0.072 12.3 3.5 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Syntaxin-6_N PF09177.6 EON99526.1 - 0.082 13.3 17.1 0.75 10.2 1.5 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 EON99526.1 - 0.097 12.4 32.6 0.53 10.0 9.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3166 PF11365.3 EON99526.1 - 0.11 12.9 18.9 1.8 9.0 8.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) Seryl_tRNA_N PF02403.17 EON99526.1 - 0.13 12.3 0.5 0.13 12.3 0.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.7 EON99526.1 - 0.17 10.0 24.2 0.029 12.5 3.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Lebercilin PF15619.1 EON99526.1 - 0.17 11.2 32.0 1.4 8.3 10.7 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.7 EON99526.1 - 0.22 11.2 18.1 0.065 12.9 2.6 2.4 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 EON99526.1 - 0.26 10.8 33.5 83 2.6 23.2 2.3 1 1 0 1 1 1 0 IncA protein PilJ PF13675.1 EON99526.1 - 0.35 11.2 13.1 0.87 9.9 3.6 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HAP1_N PF04849.8 EON99526.1 - 0.39 9.6 27.9 0.56 9.0 19.4 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region FlaC_arch PF05377.6 EON99526.1 - 0.5 10.3 20.3 1.3 8.9 0.2 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.16 EON99526.1 - 0.52 9.7 27.1 1.9 7.9 18.8 1.7 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 EON99526.1 - 0.53 8.6 22.6 1.2 7.5 15.7 1.5 1 1 0 1 1 1 0 AAA domain KLRAQ PF10205.4 EON99526.1 - 0.55 10.3 20.7 0.068 13.2 5.9 2.7 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TBPIP PF07106.8 EON99526.1 - 0.65 9.5 27.3 2.3 7.7 2.1 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF745 PF05335.8 EON99526.1 - 0.69 9.3 19.2 0.068 12.6 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.4 EON99526.1 - 0.72 8.1 22.9 0.12 10.8 5.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.4 EON99526.1 - 0.77 8.6 25.1 0.18 10.6 10.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EON99526.1 - 0.78 9.5 36.4 26 4.6 8.1 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF869 PF05911.6 EON99526.1 - 0.79 7.8 25.7 3.4 5.7 17.8 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 EON99526.1 - 0.85 8.0 32.4 1.2 7.4 17.5 2.6 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4201 PF13870.1 EON99526.1 - 0.9 8.9 23.7 1.2 8.5 4.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 EON99526.1 - 0.95 9.2 14.1 1.1 9.0 0.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Surfac_D-trimer PF09006.6 EON99526.1 - 1 9.1 0.0 1 9.1 0.0 2.8 4 0 0 4 4 1 0 Lung surfactant protein D coiled-coil trimerisation IFT46_B_C PF12317.3 EON99526.1 - 1 8.6 6.8 0.25 10.6 2.1 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal WXG100 PF06013.7 EON99526.1 - 1 9.4 16.1 3.1 7.8 0.3 4.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF3584 PF12128.3 EON99526.1 - 1.1 6.5 28.0 2.5 5.2 19.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Striatin PF08232.7 EON99526.1 - 1.2 9.4 24.8 0.95 9.7 10.3 2.2 1 1 1 2 2 2 0 Striatin family Cortex-I_coil PF09304.5 EON99526.1 - 1.3 9.1 27.8 2.9 7.9 0.2 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF3450 PF11932.3 EON99526.1 - 1.3 8.2 24.2 2.3 7.4 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HOOK PF05622.7 EON99526.1 - 1.3 6.7 25.1 1.6 6.4 17.4 1.2 1 0 0 1 1 1 0 HOOK protein FliD_N PF02465.13 EON99526.1 - 2 8.8 11.7 4.5 7.7 0.5 3.1 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus rRNA_proc-arch PF13234.1 EON99526.1 - 2.2 7.3 15.1 1e+02 1.8 10.4 2.4 1 1 0 1 1 1 0 rRNA-processing arch domain CDC37_N PF03234.9 EON99526.1 - 3.6 7.8 22.7 16 5.7 15.7 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding HSP70 PF00012.15 EON99526.1 - 4.2 5.1 18.5 5.2 4.8 12.8 1.3 1 0 0 1 1 1 0 Hsp70 protein Jnk-SapK_ap_N PF09744.4 EON99526.1 - 4.4 7.2 26.0 0.53 10.2 7.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Lge1 PF11488.3 EON99526.1 - 5.2 7.3 21.3 4.6 7.5 3.9 3.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Uds1 PF15456.1 EON99526.1 - 6.6 6.7 25.0 2 8.4 7.6 2.6 1 1 2 3 3 3 0 Up-regulated During Septation V_ATPase_I PF01496.14 EON99526.1 - 7.4 4.2 20.4 6.4 4.4 13.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2228 PF10228.4 EON99526.1 - 8.8 5.7 8.5 1 8.8 2.2 1.8 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) DUF972 PF06156.8 EON99526.1 - 9 6.7 25.4 21 5.5 8.6 3.1 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Rab5-bind PF09311.6 EON99526.1 - 9.6 6.0 31.4 3.1 7.6 1.0 2.0 1 1 1 2 2 2 0 Rabaptin-like protein Nup54 PF13874.1 EON99526.1 - 9.9 5.8 22.9 7.8 6.1 5.1 2.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Trm112p PF03966.11 EON99527.1 - 1.8e-16 60.2 0.1 2.2e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EON99527.1 - 0.033 14.4 0.2 0.059 13.6 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2554 PF10829.3 EON99527.1 - 0.26 11.4 1.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Pro_isomerase PF00160.16 EON99529.1 - 4.8e-46 156.7 0.7 6.1e-46 156.4 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Porin_3 PF01459.17 EON99530.1 - 1.9e-80 270.1 0.2 2.2e-80 269.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin ATP-synt_ab PF00006.20 EON99531.1 - 6.4e-115 382.0 0.0 8.7e-115 381.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EON99531.1 - 4.6e-19 68.9 0.6 8.2e-19 68.1 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EON99531.1 - 1.3e-13 50.9 4.2 3.4e-13 49.6 2.5 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.17 EON99531.1 - 0.026 14.5 1.0 7.1 6.7 0.1 4.1 5 0 0 5 5 5 0 Peptidase family M23 GLE1 PF07817.8 EON99532.1 - 1.1e-21 77.0 1.4 2.4e-20 72.5 0.2 2.5 2 1 0 2 2 2 1 GLE1-like protein CCDC66 PF15236.1 EON99532.1 - 2 8.0 16.1 3.8 7.1 11.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 6PF2K PF01591.13 EON99533.1 - 3.7e-35 121.0 2.6 5.5e-35 120.4 1.8 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EON99533.1 - 9.1e-22 77.8 0.3 1.5e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Syntaxin-6_N PF09177.6 EON99534.1 - 1.4e-19 70.2 0.2 9.2e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EON99534.1 - 1.7e-13 50.0 8.3 3.5e-13 49.0 2.2 2.9 3 0 0 3 3 3 1 SNARE domain CK2S PF15011.1 EON99534.1 - 0.044 13.5 2.4 0.83 9.4 0.1 2.3 2 1 0 2 2 2 0 Casein Kinase 2 substrate Fez1 PF06818.10 EON99534.1 - 0.082 12.9 3.6 0.13 12.2 2.5 1.4 1 1 0 1 1 1 0 Fez1 Spc24 PF08286.6 EON99534.1 - 0.2 11.3 3.4 0.45 10.2 0.1 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DegS PF05384.6 EON99534.1 - 0.45 9.7 4.7 0.38 9.9 1.0 2.2 2 1 1 3 3 3 0 Sensor protein DegS COG2 PF06148.6 EON99534.1 - 0.51 10.2 5.2 3.7 7.4 0.4 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1470 PF07336.6 EON99534.1 - 3.5 7.9 9.4 2.2 8.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1470) CCDC74_C PF14917.1 EON99535.1 - 0.72 9.9 14.4 5.2 7.1 0.5 3.3 1 1 2 3 3 3 0 Coiled coil protein 74, C terminal LZ_Tnp_IS66 PF13007.2 EON99535.1 - 5.4 7.7 44.6 0.56 10.8 3.3 5.1 1 1 3 5 5 5 0 Transposase C of IS166 homeodomain DNA_pol_B PF00136.16 EON99536.1 - 1.7e-147 491.9 1.9 2.4e-147 491.4 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EON99536.1 - 1e-80 271.0 0.7 3.8e-80 269.1 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EON99536.1 - 1.8e-21 75.8 3.7 3.8e-21 74.8 2.2 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EON99536.1 - 0.0005 19.9 0.3 0.0037 17.0 0.2 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EON99536.1 - 0.0008 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EON99536.1 - 2.6 7.8 9.1 1.6 8.5 0.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metallophos PF00149.23 EON99537.1 - 7.1e-12 45.1 0.2 1.3e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EON99537.1 - 0.0008 19.2 0.1 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 EON99537.1 - 0.06 12.8 0.0 0.39 10.2 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Securin PF04856.8 EON99538.1 - 0.039 13.6 0.2 0.039 13.6 0.2 1.9 2 0 0 2 2 2 0 Securin sister-chromatid separation inhibitor Alb1 PF09135.6 EON99538.1 - 4.1 8.0 6.6 5.3 7.7 0.1 2.9 2 1 1 3 3 3 0 Alb1 DUF4048 PF13257.1 EON99539.1 - 1.5e-13 51.0 16.7 8.5e-11 41.9 7.6 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF4048) DUF2046 PF09755.4 EON99539.1 - 0.0083 15.0 1.2 0.012 14.5 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Voldacs PF03517.8 EON99540.1 - 3.4e-12 46.3 1.9 5.4e-12 45.7 1.3 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling ELFV_dehydrog PF00208.16 EON99541.1 - 2.8e-83 279.2 3.0 3.5e-83 278.9 2.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EON99541.1 - 2.2e-47 159.8 0.0 6.1e-47 158.4 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EON99541.1 - 0.0016 18.6 0.1 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ATP-synt_S1 PF05827.7 EON99542.1 - 2.9e-44 151.5 0.0 7.1e-44 150.2 0.0 1.6 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) N-SET PF11764.3 EON99543.1 - 1e-44 152.3 0.4 1e-44 152.3 0.3 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EON99543.1 - 2.9e-24 86.2 0.2 2.9e-24 86.2 0.1 3.0 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 EON99543.1 - 1.1e-23 82.3 1.7 2.9e-23 80.9 1.2 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 EON99543.1 - 0.012 15.2 0.1 0.3 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NT-C2 PF10358.4 EON99544.1 - 1.5e-27 95.8 0.0 1.3e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PCI PF01399.22 EON99545.1 - 8.8e-22 77.4 0.0 3.2e-21 75.6 0.0 2.0 1 0 0 1 1 1 1 PCI domain Atrophin-1 PF03154.10 EON99545.1 - 6 4.8 5.2 8 4.4 3.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF4336 PF14234.1 EON99546.1 - 2.3e-19 69.6 0.0 1.5e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) DASH_Spc19 PF08287.6 EON99547.1 - 2.5e-42 144.0 0.2 3.1e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Spc19 Surfac_D-trimer PF09006.6 EON99547.1 - 0.048 13.3 0.2 3.9 7.2 0.4 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF1843 PF08898.5 EON99547.1 - 7 6.7 10.0 11 6.1 3.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF1726 PF08351.6 EON99549.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Pal1 PF08316.6 EON99550.1 - 1.9e-47 161.2 0.5 1.9e-47 161.2 0.4 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein RNA_polI_A34 PF08208.6 EON99550.1 - 1.9 8.1 9.7 3.4 7.2 6.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DLIC PF05783.6 EON99551.1 - 1.6e-13 50.1 0.5 1e-12 47.5 0.0 2.4 4 0 0 4 4 4 1 Dynein light intermediate chain (DLIC) NUDIX PF00293.23 EON99552.1 - 6.5e-11 42.0 0.1 3.1e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain PAS_7 PF12860.2 EON99552.1 - 0.11 12.5 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 PAS fold FAD_binding_4 PF01565.18 EON99553.1 - 6.9e-17 61.2 2.7 1e-16 60.6 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EON99553.1 - 2.9e-10 40.1 0.8 0.00027 20.6 0.0 2.6 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_5 PF00941.16 EON99553.1 - 0.0055 16.1 0.1 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase ATP-synt_C PF00137.16 EON99554.1 - 1.8e-26 91.8 29.4 8.8e-16 57.5 5.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Abhydrolase_5 PF12695.2 EON99555.1 - 4.4e-12 45.9 0.7 1.4e-11 44.3 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON99555.1 - 2.9e-11 43.6 5.9 4.1e-11 43.2 4.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EON99555.1 - 6.1e-08 31.5 0.0 0.0004 18.9 0.0 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EON99555.1 - 6.6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EON99555.1 - 1.6e-05 24.2 0.0 0.00072 18.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EON99555.1 - 0.00041 20.1 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EON99555.1 - 0.017 14.6 0.1 0.16 11.4 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EON99555.1 - 0.021 14.6 0.1 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 Putative lysophospholipase DUF2048 PF09752.4 EON99555.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) UPF0139 PF03669.8 EON99556.1 - 1.1e-06 28.1 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Glyco_hydro_16 PF00722.16 EON99558.1 - 2.9e-18 65.8 2.2 5.9e-18 64.8 1.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 EON99558.1 - 0.04 13.6 0.1 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain PTCRA PF15028.1 EON99558.1 - 0.19 11.3 0.9 2.6 7.6 0.3 2.2 2 0 0 2 2 2 0 Pre-T-cell antigen receptor p450 PF00067.17 EON99559.1 - 2e-23 82.6 0.0 2.4e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydro_lipase PF04083.11 EON99560.1 - 2.1e-20 71.8 0.0 3.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EON99560.1 - 9.8e-19 67.8 0.2 6e-18 65.2 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EON99560.1 - 5.8e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EON99560.1 - 0.0013 18.2 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Beach PF02138.13 EON99561.1 - 8.8e-108 359.8 0.0 1.7e-107 358.9 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EON99561.1 - 1e-13 51.0 0.0 2.5e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EON99561.1 - 1.2e-10 40.8 0.1 0.0022 17.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PRP38 PF03371.10 EON99562.1 - 6.2e-62 208.2 0.0 7.5e-62 207.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ribosomal_S28e PF01200.13 EON99563.1 - 6.5e-34 115.4 2.1 7.1e-34 115.3 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Isy1 PF06246.7 EON99564.1 - 3.1e-88 295.4 2.1 5.7e-88 294.6 1.4 1.4 1 1 0 1 1 1 1 Isy1-like splicing family NIPSNAP PF07978.8 EON99565.1 - 6e-26 90.4 2.5 5.1e-16 58.5 0.0 2.9 3 0 0 3 3 3 2 NIPSNAP Pirin PF02678.11 EON99566.1 - 9e-25 86.6 0.6 2.8e-24 85.0 0.4 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EON99566.1 - 0.00076 18.9 2.8 0.033 13.6 0.6 3.0 2 1 0 2 2 2 2 Cupin domain MmgE_PrpD PF03972.9 EON99567.1 - 1.7e-149 497.7 0.0 1.9e-149 497.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family UPF0079 PF02367.12 EON99567.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF605 PF04652.11 EON99569.1 - 4 6.7 10.0 4.7 6.5 6.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF3580 PF12117.3 EON99570.1 - 0.022 14.6 0.3 0.073 13.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3580) RNA_pol_3_Rpc31 PF11705.3 EON99571.1 - 0.079 12.8 5.7 0.14 12.0 4.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 EON99571.1 - 0.2 10.1 4.6 0.29 9.5 3.2 1.2 1 0 0 1 1 1 0 Daxx Family SET PF00856.23 EON99571.1 - 0.31 11.3 3.3 0.53 10.5 2.3 1.5 1 1 0 1 1 1 0 SET domain Nucleoplasmin PF03066.10 EON99571.1 - 0.41 10.1 2.9 0.81 9.1 2.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin RepB-RCR_reg PF10723.4 EON99571.1 - 0.75 9.5 4.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Replication regulatory protein RepB NP1-WLL PF11733.3 EON99571.1 - 4.9 7.4 11.9 4.3 7.6 4.4 2.4 2 1 0 2 2 2 0 Non-capsid protein NP1 Transaldolase PF00923.14 EON99572.1 - 1.5e-93 313.0 1.5 1.8e-93 312.7 1.1 1.0 1 0 0 1 1 1 1 Transaldolase CAP PF00188.21 EON99573.1 - 1.7e-15 57.6 4.3 2.3e-15 57.1 3.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF605 PF04652.11 EON99573.1 - 2.5 7.3 17.7 3.2 7.0 12.3 1.1 1 0 0 1 1 1 0 Vta1 like TRI12 PF06609.8 EON99574.1 - 3.7e-56 190.5 19.0 1.3e-54 185.4 12.8 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EON99574.1 - 5.3e-10 38.5 38.7 5.3e-10 38.5 26.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.3 EON99574.1 - 0.55 9.7 6.0 0.16 11.5 0.3 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) DUF4131 PF13567.1 EON99574.1 - 3.5 7.0 14.4 1.7 7.9 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) IBR PF01485.16 EON99575.1 - 0.012 15.4 4.1 0.031 14.1 2.8 1.7 1 0 0 1 1 1 0 IBR domain MethyltransfD12 PF02086.10 EON99575.1 - 0.1 12.0 6.5 0.021 14.3 1.4 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase HTH_12 PF08461.5 EON99575.1 - 0.54 10.0 8.1 0.046 13.4 1.0 2.8 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain MMR_HSR1 PF01926.18 EON99576.1 - 3.4e-12 46.3 0.0 5.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EON99576.1 - 0.0041 17.1 0.3 2.5 8.0 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain Arf PF00025.16 EON99576.1 - 0.0094 15.2 0.1 0.036 13.3 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EON99576.1 - 0.0099 15.7 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EON99576.1 - 0.014 14.6 0.2 0.05 12.8 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 EON99576.1 - 0.024 13.8 2.3 0.45 9.6 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EON99576.1 - 0.087 13.6 0.4 0.62 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EON99576.1 - 0.12 12.4 0.0 3.5 7.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EON99576.1 - 0.17 12.1 0.2 0.51 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EON99576.1 - 0.17 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.1 EON99576.1 - 0.78 9.6 2.7 1.4 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain HSP70 PF00012.15 EON99577.1 - 2.6e-78 263.4 0.9 2.6e-78 263.4 0.6 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EON99577.1 - 1.1e-07 30.7 0.1 1.8e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein CENP-B_dimeris PF09026.5 EON99577.1 - 0.023 14.9 2.0 0.064 13.5 1.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Gar1 PF04410.9 EON99577.1 - 0.033 13.6 0.3 0.075 12.4 0.2 1.6 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region PBP1_TM PF14812.1 EON99577.1 - 2.7 8.3 9.8 0.68 10.2 4.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SH3_1 PF00018.23 EON99578.1 - 2.7e-09 36.2 0.1 4.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON99578.1 - 5.3e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EON99578.1 - 1.3e-06 27.7 0.0 2.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF754 PF05449.6 EON99578.1 - 2.3 8.3 6.4 1.2 9.2 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF754) Transp_cyt_pur PF02133.10 EON99579.1 - 2.1e-46 158.3 22.2 2.7e-46 158.0 15.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RRM_1 PF00076.17 EON99580.1 - 2.8e-14 52.4 0.0 3.5e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99580.1 - 3.2e-10 39.8 0.0 7.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99580.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YjeF_N PF03853.10 EON99581.1 - 3.3e-25 88.6 0.0 3.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus S1-P1_nuclease PF02265.11 EON99582.1 - 2.2e-73 246.9 0.0 2.5e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease STAT_alpha PF01017.15 EON99582.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain SNase PF00565.12 EON99583.1 - 7.6e-73 241.6 1.9 1.3e-22 80.1 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EON99583.1 - 2.8e-23 82.0 0.0 6.1e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EON99583.1 - 1.2e-06 27.8 0.0 3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Rpp20 PF12328.3 EON99584.1 - 2.2e-23 82.5 0.1 3.8e-23 81.7 0.1 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EON99584.1 - 9.4e-14 50.7 0.0 1.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Alba RNR_inhib PF08591.5 EON99585.1 - 6.6e-21 75.0 0.0 2.2e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Pectate_lyase_3 PF12708.2 EON99586.1 - 3.8e-74 249.5 19.2 7.3e-63 212.7 3.2 3.4 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EON99586.1 - 1.8e-07 30.4 1.3 0.0084 15.5 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Cytochrom_C_2 PF01322.15 EON99586.1 - 0.068 13.7 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C' CNH PF00780.17 EON99587.1 - 2.3e-66 224.0 0.0 3.8e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EON99587.1 - 8.7e-30 103.9 1.3 9.8e-30 103.7 0.3 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EON99587.1 - 1.9e-13 50.5 0.0 1.9e-12 47.2 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EON99587.1 - 2.1e-05 24.6 0.0 0.00011 22.3 0.0 2.3 2 1 0 2 2 2 1 PH domain Viral_env_E26 PF11050.3 EON99587.1 - 0.28 10.3 2.0 1.3 8.2 0.7 2.2 2 0 0 2 2 2 0 Virus envelope protein E26 Amidase PF01425.16 EON99588.1 - 7.8e-104 347.9 0.1 1.2e-103 347.3 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF3693 PF12472.3 EON99588.1 - 0.00065 19.2 0.0 0.002 17.6 0.0 1.8 1 0 0 1 1 1 1 Phage related protein DUF4360 PF14273.1 EON99589.1 - 2.1e-73 245.9 6.5 2.4e-73 245.7 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) tRNA-synt_2 PF00152.15 EON99590.1 - 5.8e-32 110.7 0.0 5.8e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) TRAM_LAG1_CLN8 PF03798.11 EON99591.1 - 1.5e-39 135.6 11.7 1.5e-39 135.6 8.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EON99591.1 - 1.6e-19 69.1 0.3 1.6e-19 69.1 0.2 2.0 2 0 0 2 2 2 1 TRAM1-like protein Pkinase PF00069.20 EON99592.1 - 1.5e-38 132.4 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99592.1 - 8.2e-14 51.2 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EON99592.1 - 1.7e-05 24.7 0.0 0.0014 18.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EON99592.1 - 0.053 12.3 0.1 0.08 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Citrate_synt PF00285.16 EON99593.1 - 2.6e-103 345.4 0.0 3.1e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Polysacc_lyase PF14099.1 EON99594.1 - 1e-45 156.1 6.8 1.3e-45 155.8 4.7 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Med12-LCEWAV PF12145.3 EON99595.1 - 0.0012 17.4 0.3 0.12 10.7 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic Mediator 12 subunit domain CFEM PF05730.6 EON99597.1 - 0.0021 17.8 2.3 0.0021 17.8 1.6 3.2 2 0 0 2 2 2 1 CFEM domain CNH PF00780.17 EON99598.1 - 2.5e-83 279.6 0.0 8.5e-83 277.9 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EON99598.1 - 4.5e-43 146.4 0.0 9.2e-43 145.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EON99598.1 - 5.6e-39 133.8 0.1 2.8e-38 131.5 0.3 2.1 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 EON99598.1 - 2.7e-14 52.6 0.0 5.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2_3 PF14378.1 EON99598.1 - 0.17 11.3 0.0 0.43 10.0 0.0 1.6 2 0 0 2 2 2 0 PAP2 superfamily Mannitol_dh_C PF08125.8 EON99599.1 - 5.1e-76 255.0 0.0 8.3e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EON99599.1 - 7.3e-45 152.5 0.0 1.3e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Kelch_5 PF13854.1 EON99601.1 - 4.2e-10 39.3 12.0 5.1e-07 29.5 0.1 5.0 5 0 0 5 5 4 2 Kelch motif DUF1191 PF06697.7 EON99601.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 EON99601.1 - 0.0019 17.7 0.2 0.0035 16.8 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.1 EON99601.1 - 0.0035 16.9 7.6 0.0035 16.9 5.3 2.0 2 0 0 2 2 1 1 Glycine zipper EphA2_TM PF14575.1 EON99601.1 - 0.0075 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EON99601.1 - 0.013 13.8 0.0 0.019 13.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YajC PF02699.10 EON99601.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Syndecan PF01034.15 EON99601.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.8 EON99601.1 - 0.079 12.4 8.3 0.2 11.1 5.8 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Lamp PF01299.12 EON99601.1 - 0.1 11.7 0.3 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Kelch_6 PF13964.1 EON99601.1 - 0.19 11.9 9.9 17 5.8 0.0 5.7 5 1 1 6 6 6 0 Kelch motif Gly-zipper_YMGG PF13441.1 EON99601.1 - 0.54 9.8 11.4 0.024 14.1 3.6 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper SKG6 PF08693.5 EON99601.1 - 3.3 7.1 9.8 0.039 13.2 0.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_2 PF07646.10 EON99601.1 - 3.3 7.6 5.8 6.7 6.6 0.1 3.9 4 1 0 4 4 3 0 Kelch motif Rick_17kDa_Anti PF05433.10 EON99601.1 - 3.9 7.2 15.3 0.079 12.6 5.6 1.9 2 0 0 2 2 1 0 Glycine zipper 2TM domain UQ_con PF00179.21 EON99602.1 - 4.9e-37 126.4 0.0 5.7e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EON99602.1 - 3.9e-05 23.4 0.0 4.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EON99602.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EON99602.1 - 0.033 14.0 0.1 0.045 13.6 0.1 1.5 1 1 0 1 1 1 0 RWD domain Bax1-I PF01027.15 EON99603.1 - 1.5e-50 171.6 25.7 1.8e-50 171.4 17.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SIP1 PF04938.7 EON99606.1 - 0.15 11.3 1.8 6.6 6.0 0.0 3.6 2 2 1 4 4 4 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3034 PF11231.3 EON99606.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) RbcS PF12338.3 EON99606.1 - 0.45 10.3 5.9 3.1 7.6 0.1 3.1 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit 2OG-FeII_Oxy_2 PF13532.1 EON99607.1 - 2.6e-19 69.8 0.0 5.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_3 PF00933.16 EON99608.1 - 1.3e-57 195.0 0.0 2.1e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON99608.1 - 3.7e-39 134.5 2.2 5.8e-39 133.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON99608.1 - 7.5e-05 22.5 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain NTP_transf_3 PF12804.2 EON99608.1 - 0.022 14.8 0.5 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 MobA-like NTP transferase domain Shadoo PF14999.1 EON99608.1 - 0.27 11.0 4.3 12 5.7 1.0 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DLH PF01738.13 EON99609.1 - 4e-10 39.3 0.0 5.6e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EON99609.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Phosducin PF02114.11 EON99612.1 - 4.3e-14 51.8 0.0 6.8e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EON99612.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Fasciclin PF02469.17 EON99614.1 - 2.3e-42 143.9 0.1 1.2e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain RabGAP-TBC PF00566.13 EON99615.1 - 3.6e-46 157.3 0.0 5.4e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EON99615.1 - 5.8e-08 31.9 0.4 0.0083 15.9 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EON99615.1 - 4.8e-07 28.6 0.2 0.07 12.4 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EON99615.1 - 1.1e-05 25.4 0.2 0.00012 22.1 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EON99615.1 - 0.00043 19.4 0.7 0.058 12.7 0.6 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EON99615.1 - 0.016 14.7 0.0 9.7 5.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair GRAM PF02893.15 EON99615.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Asp PF00026.18 EON99616.1 - 7.5e-38 130.5 0.0 1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON99616.1 - 8.8e-14 51.7 0.3 3e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Carboxyl_trans PF01039.17 EON99617.1 - 1.9e-142 475.0 0.0 2.7e-142 474.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EON99617.1 - 0.0051 16.0 0.0 0.98 8.5 0.0 2.8 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Sugar_tr PF00083.19 EON99618.1 - 3.5e-34 118.1 13.5 4.2e-34 117.9 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99618.1 - 3.8e-05 22.5 41.3 0.00073 18.3 9.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.18 EON99619.1 - 2.2e-63 214.4 7.7 2.6e-63 214.1 5.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EON99619.1 - 3e-13 50.0 0.6 3e-12 46.8 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EON99619.1 - 0.0031 17.9 4.3 1.3 9.6 0.3 3.5 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EON99619.1 - 0.018 14.5 0.0 0.28 10.7 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal RVP PF00077.15 EON99619.1 - 0.023 14.6 0.2 20 5.1 0.0 3.3 3 0 0 3 3 3 0 Retroviral aspartyl protease WD40 PF00400.27 EON99620.1 - 6.2e-30 101.9 2.8 6.9e-06 25.7 0.0 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat adh_short PF00106.20 EON99621.1 - 1.6e-28 99.7 2.5 2.2e-28 99.2 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99621.1 - 3.4e-14 53.2 0.0 4.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99621.1 - 9.1e-11 41.7 1.7 1.4e-10 41.1 1.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EON99621.1 - 1.3e-05 24.9 0.3 2.3e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EON99621.1 - 0.0032 16.9 0.1 0.0046 16.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 EON99621.1 - 0.022 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EON99621.1 - 0.042 12.7 0.1 0.071 11.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EON99621.1 - 0.06 12.0 0.1 0.39 9.3 0.1 1.9 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 EON99621.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Eno-Rase_NADH_b PF12242.3 EON99621.1 - 0.15 11.8 1.3 0.76 9.6 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_S27e PF01667.12 EON99622.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EON99622.1 - 0.0093 15.8 1.5 0.011 15.6 1.0 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EON99622.1 - 0.3 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Carn_acyltransf PF00755.15 EON99623.1 - 2.2e-65 220.8 0.0 3.1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PP-binding PF00550.20 EON99623.1 - 0.0015 18.7 0.7 0.007 16.6 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF982 PF06169.7 EON99623.1 - 0.0052 16.4 2.0 0.059 13.1 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF982) Pyridoxal_deC PF00282.14 EON99624.1 - 1.7e-59 201.1 0.0 2.5e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EON99624.1 - 0.00034 19.4 0.0 0.00068 18.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V NUDIX PF00293.23 EON99625.1 - 1.5e-07 31.1 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nse4_C PF08743.5 EON99626.1 - 4.9e-18 64.9 0.0 1.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EON99626.1 - 2.2e-14 53.0 0.0 7.5e-14 51.3 0.0 2.0 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Focal_AT PF03623.8 EON99626.1 - 0.0028 17.1 1.2 0.0068 15.8 0.8 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region DUF2465 PF10239.4 EON99626.1 - 0.052 12.7 0.2 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) DUF1484 PF07363.6 EON99626.1 - 0.13 12.6 2.0 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Pro-rich_19 PF15455.1 EON99626.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Proline-rich 19 zf-C4H2 PF10146.4 EON99626.1 - 0.39 10.7 6.0 0.7 9.8 0.4 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4208 PF13907.1 EON99626.1 - 0.63 10.2 2.7 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) YtxH PF12732.2 EON99626.1 - 5.3 7.4 5.2 15 6.0 0.1 2.5 2 0 0 2 2 2 0 YtxH-like protein zf-P11 PF03854.9 EON99627.1 - 0.0063 15.9 2.1 0.0098 15.3 1.4 1.2 1 0 0 1 1 1 1 P-11 zinc finger Myticin-prepro PF10690.4 EON99627.1 - 0.16 12.0 0.6 0.18 11.8 0.4 1.2 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel RTA1 PF04479.8 EON99628.1 - 3.7e-50 170.5 2.0 5e-50 170.0 1.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Nucleoporin_FG PF13634.1 EON99631.1 - 0.0025 17.9 0.2 0.0034 17.6 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin FG repeat region HisKA PF00512.20 EON99631.1 - 0.51 10.3 3.9 0.83 9.6 2.7 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain CAF-1_p150 PF11600.3 EON99631.1 - 0.51 9.6 9.3 0.93 8.8 6.4 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PQ-loop PF04193.9 EON99632.1 - 2.5e-40 135.8 5.8 1.4e-20 72.6 0.4 3.1 2 0 0 2 2 2 2 PQ loop repeat WSC PF01822.14 EON99633.1 - 1.9e-20 72.5 77.5 7.1e-11 41.8 5.4 5.7 6 0 0 6 6 6 4 WSC domain ADH_zinc_N PF00107.21 EON99634.1 - 2.5e-10 40.0 0.0 4.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON99634.1 - 4.2e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.1 EON99635.1 - 1.9e-27 96.5 0.0 2.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EON99635.1 - 2.4e-21 76.3 0.7 2.4e-21 76.3 0.5 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON99635.1 - 2.8e-10 40.1 0.4 2.8e-10 40.1 0.3 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EON99636.1 - 2.8e-10 40.3 0.0 4.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EON99636.1 - 2.6e-06 27.5 0.1 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EON99636.1 - 0.00045 20.0 0.0 0.00071 19.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99636.1 - 0.018 14.7 0.1 0.07 12.7 0.1 2.0 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EON99636.1 - 0.074 11.9 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Thioredox_DsbH PF03190.10 EON99637.1 - 5.2e-61 205.1 0.0 8.8e-61 204.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EON99637.1 - 2.3e-07 30.7 0.0 4.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.6 EON99637.1 - 0.0029 16.6 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) STAS_2 PF13466.1 EON99637.1 - 0.015 15.2 0.4 1.3 9.1 0.0 2.9 2 1 0 2 2 2 0 STAS domain DUF2267 PF10025.4 EON99637.1 - 0.019 15.0 0.3 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Glyco_hydro_9 PF00759.14 EON99637.1 - 0.023 13.6 1.2 0.042 12.7 0.9 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Thioredoxin_2 PF13098.1 EON99637.1 - 0.051 13.7 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Med12 PF09497.5 EON99638.1 - 5.1e-28 96.8 0.2 1e-27 95.8 0.2 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ER-remodelling PF14755.1 EON99638.1 - 0.017 15.2 5.6 0.037 14.1 3.9 1.5 1 0 0 1 1 1 0 Intracellular membrane remodeller Ank_5 PF13857.1 EON99639.1 - 9.3e-05 22.5 0.2 0.0002 21.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EON99639.1 - 0.0031 17.2 0.3 0.0069 16.1 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EON99639.1 - 0.038 14.3 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Reo_sigmaC PF04582.7 EON99641.1 - 5e-06 25.9 4.7 0.00069 18.8 0.3 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EON99641.1 - 0.00071 19.4 4.3 0.00071 19.4 3.0 2.7 1 1 0 2 2 2 1 Tropomyosin like BLOC1_2 PF10046.4 EON99641.1 - 0.053 13.6 11.9 2 8.6 2.8 3.2 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EON99641.1 - 0.062 11.7 15.3 0.091 11.2 10.5 1.3 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EON99641.1 - 0.064 13.7 17.5 7 7.1 0.8 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Pox_A_type_inc PF04508.7 EON99641.1 - 0.084 12.6 0.0 0.084 12.6 0.0 4.5 7 0 0 7 7 4 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 EON99641.1 - 0.095 12.6 5.3 6.6 6.7 1.3 3.2 2 1 0 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 EON99641.1 - 0.19 9.5 9.7 0.23 9.2 0.5 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3373 PF11853.3 EON99641.1 - 0.2 10.1 3.5 0.4 9.1 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IncA PF04156.9 EON99641.1 - 0.48 9.9 25.0 5 6.6 11.5 3.1 1 1 1 2 2 2 0 IncA protein Vfa1 PF08432.5 EON99641.1 - 0.49 10.3 12.6 0.021 14.8 0.8 2.3 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AIF-MLS PF14962.1 EON99641.1 - 0.86 9.2 4.9 0.21 11.2 0.8 1.8 2 0 0 2 2 2 0 Mitochondria Localisation Sequence NPV_P10 PF05531.7 EON99641.1 - 1.4 9.2 10.3 2.6 8.3 0.8 3.6 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.8 EON99641.1 - 2.3 7.7 14.7 3.7 7.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF2730 PF10805.3 EON99641.1 - 4.5 7.0 6.9 4.8 6.9 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) FUSC PF04632.7 EON99641.1 - 7.2 4.9 8.9 2.9 6.2 4.4 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family bZIP_1 PF00170.16 EON99641.1 - 9.1 6.3 14.5 5.6 6.9 3.1 3.7 3 1 0 3 3 3 0 bZIP transcription factor Pkinase PF00069.20 EON99642.1 - 2.5e-64 216.9 0.0 2.9e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99642.1 - 5.8e-32 110.7 0.0 7.6e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON99642.1 - 8e-06 25.0 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON99642.1 - 0.0048 16.6 0.0 0.024 14.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EON99642.1 - 0.029 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ICL PF00463.16 EON99644.1 - 1.5e-201 670.1 0.1 1.8e-201 669.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EON99644.1 - 5.9e-12 45.3 0.0 1.1e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EON99644.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain SH3_1 PF00018.23 EON99645.1 - 1.5e-14 53.1 0.0 2.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EON99645.1 - 7.1e-10 38.3 0.0 1.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EON99645.1 - 2.2e-07 30.2 0.0 3.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PRCC PF10253.4 EON99645.1 - 3.4 8.3 5.6 2.5 8.7 1.8 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Septin PF00735.13 EON99646.1 - 1.5e-101 339.1 0.3 4e-101 337.7 0.0 1.8 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EON99646.1 - 0.0037 17.2 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EON99646.1 - 0.099 12.0 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EON99646.1 - 0.26 11.0 4.7 0.91 9.3 0.0 2.9 2 1 1 3 3 3 0 Dynamin family V_ATPase_I PF01496.14 EON99646.1 - 3.8 5.2 5.8 5.7 4.6 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3653 PF12375.3 EON99646.1 - 8.4 6.6 9.8 4.2 7.6 0.2 3.2 2 1 1 3 3 3 0 Phage protein Metallophos PF00149.23 EON99647.1 - 3.1e-11 43.0 0.1 1e-10 41.3 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EON99647.1 - 6.1e-10 39.1 0.1 1.6e-09 37.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Serglycin PF04360.7 EON99647.1 - 1.6 8.4 6.0 11 5.7 0.4 2.2 2 0 0 2 2 2 0 Serglycin MFS_1 PF07690.11 EON99648.1 - 6.2e-18 64.6 11.3 3.8e-11 42.3 4.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF360 PF04020.8 EON99648.1 - 0.0049 17.2 5.4 0.012 15.9 3.8 1.7 1 0 0 1 1 1 1 Membrane protein of unknown function DUF3112 PF11309.3 EON99648.1 - 0.045 13.5 1.3 0.088 12.6 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) COX2_TM PF02790.10 EON99648.1 - 0.058 13.3 2.4 0.11 12.4 0.5 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain NfeD PF01957.13 EON99648.1 - 0.28 11.3 6.1 13 5.9 2.8 2.5 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding zf-DHHC PF01529.15 EON99648.1 - 0.97 8.8 3.7 5.4 6.3 2.6 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase Trp_DMAT PF11991.3 EON99649.1 - 1.5e-81 274.3 0.0 2.9e-81 273.4 0.0 1.4 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Abhydrolase_6 PF12697.2 EON99650.1 - 8e-08 32.4 0.0 9.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DEAD_2 PF06733.10 EON99652.1 - 1.1e-49 168.2 0.2 2e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EON99652.1 - 3.2e-44 150.8 0.0 1.6e-43 148.5 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1227 PF06777.6 EON99652.1 - 6.3e-34 116.7 0.3 1.4e-25 89.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1227) SNF2_N PF00176.18 EON99652.1 - 0.00039 19.3 0.3 0.01 14.6 0.2 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EON99652.1 - 0.003 17.4 0.3 0.026 14.3 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EON99652.1 - 0.0033 17.0 0.0 0.0073 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EON99652.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EON99652.1 - 0.064 12.4 0.2 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Exo_endo_phos PF03372.18 EON99653.1 - 2.9e-15 56.9 1.0 8e-15 55.4 0.7 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF695 PF05117.7 EON99653.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF695) DDOST_48kD PF03345.9 EON99654.1 - 9.6e-160 531.7 0.0 1.1e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Glyco_hydro_18 PF00704.23 EON99655.1 - 2.5e-18 66.6 5.3 2.5e-18 66.6 3.7 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EON99655.1 - 4.1e-06 26.5 0.0 8.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain Acyl-CoA_dh_1 PF00441.19 EON99656.1 - 2.7e-41 141.1 1.1 6e-41 140.0 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EON99656.1 - 1e-31 109.8 0.6 2.1e-31 108.7 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EON99656.1 - 1.1e-18 66.4 0.3 3.1e-18 65.0 0.1 1.8 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EON99656.1 - 3.6e-12 46.6 0.2 8.1e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EON99656.1 - 0.00059 19.2 0.4 0.0027 17.1 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AhpC-TSA PF00578.16 EON99656.1 - 0.11 12.1 0.1 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family AMP-binding PF00501.23 EON99657.1 - 1.8e-34 118.8 0.1 2.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON99657.1 - 2.1e-14 54.2 0.1 4.3e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pet191_N PF10203.4 EON99658.1 - 6.9e-28 96.4 4.5 8.9e-28 96.1 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Clusterin PF01093.12 EON99658.1 - 0.63 8.7 2.8 0.76 8.5 2.0 1.1 1 0 0 1 1 1 0 Clusterin Glyco_trans_2_3 PF13632.1 EON99659.1 - 1e-47 162.4 2.4 1e-47 162.4 1.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON99659.1 - 2.2e-07 30.9 0.0 5.8e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EON99659.1 - 1.4e-05 24.8 0.0 4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EON99659.1 - 0.0031 16.8 0.0 0.0072 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 PI3Ka PF00613.15 EON99660.1 - 3.9e-62 208.7 2.0 3.9e-62 208.7 1.4 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EON99660.1 - 6.6e-44 150.1 0.0 1.8e-42 145.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EON99660.1 - 2.9e-34 117.8 0.1 4.9e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 EON99660.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Metallophos PF00149.23 EON99661.1 - 1.4e-06 27.8 5.0 3.9e-06 26.3 3.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sod_Cu PF00080.15 EON99662.1 - 1.9e-44 151.2 5.5 2.2e-44 151.0 3.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ATP12 PF07542.6 EON99663.1 - 3.6e-31 107.6 0.0 7.2e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Mob1_phocein PF03637.12 EON99664.1 - 1.8e-36 125.4 3.6 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family GDC-P PF02347.11 EON99665.1 - 6.2e-173 575.4 0.0 1.1e-155 518.5 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EON99665.1 - 4.6e-07 29.2 0.0 8.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TMF_DNA_bd PF12329.3 EON99666.1 - 0.01 15.5 5.2 0.01 15.5 3.6 7.2 6 1 1 7 7 7 0 TATA element modulatory factor 1 DNA binding Lipoprotein_20 PF13942.1 EON99666.1 - 0.19 11.2 20.0 0.049 13.1 5.6 3.2 3 0 0 3 3 3 0 YfhG lipoprotein DUF1342 PF07072.6 EON99666.1 - 9.2 5.8 13.6 1.5 8.4 2.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1342) DUF1664 PF07889.7 EON99666.1 - 10 5.9 23.5 1.9 8.2 0.8 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Peptidase_S8 PF00082.17 EON99667.1 - 4.5e-51 173.6 10.2 7.4e-51 172.9 7.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EON99667.1 - 1.5e-21 76.7 1.0 1.5e-21 76.7 0.7 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 Zn_clus PF00172.13 EON99668.1 - 2.3e-05 24.2 4.5 3.8e-05 23.5 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EON99669.1 - 1.8e-23 82.5 0.1 2.9e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON99669.1 - 4e-06 27.7 0.1 6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EON99669.1 - 0.00021 21.2 0.2 0.00033 20.6 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99669.1 - 0.001 19.1 0.1 0.002 18.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EON99669.1 - 0.039 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EON99669.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 1 1 2 2 2 0 ThiF family p450 PF00067.17 EON99670.1 - 5.1e-41 140.6 0.0 2.3e-38 131.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 EON99671.1 - 1.6e-12 47.0 4.7 2.8e-12 46.2 1.1 2.5 1 1 1 2 2 2 1 FAD binding domain ABC_tran PF00005.22 EON99672.1 - 6e-50 169.0 0.0 4.4e-27 95.0 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EON99672.1 - 7e-20 72.1 0.7 1.4e-09 38.3 0.0 3.2 2 1 1 3 3 3 3 AAA domain SMC_N PF02463.14 EON99672.1 - 3.6e-13 49.2 0.0 4.3e-05 22.8 0.0 3.9 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EON99672.1 - 1.6e-08 34.1 0.2 3.2e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 EON99672.1 - 1.7e-07 31.7 3.3 0.00064 20.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EON99672.1 - 1.9e-07 30.5 0.9 0.0075 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EON99672.1 - 8.7e-07 29.7 0.1 0.0066 17.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EON99672.1 - 1.2e-06 27.8 0.0 0.0053 15.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EON99672.1 - 1.3e-06 28.3 0.0 0.0062 16.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EON99672.1 - 5.1e-06 26.9 0.0 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 EON99672.1 - 7e-06 25.8 0.0 0.17 11.8 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EON99672.1 - 7.5e-06 25.2 0.0 0.6 9.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 EON99672.1 - 5.5e-05 22.7 3.2 0.33 10.3 0.1 3.6 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EON99672.1 - 6.4e-05 23.1 0.0 0.81 9.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EON99672.1 - 0.00039 19.8 0.0 0.7 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EON99672.1 - 0.00091 19.1 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EON99672.1 - 0.00091 19.0 0.0 0.25 11.1 0.0 3.1 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 EON99672.1 - 0.0012 18.8 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EON99672.1 - 0.0013 17.5 1.1 0.36 9.5 0.0 2.9 3 0 0 3 3 3 1 ArgK protein MobB PF03205.9 EON99672.1 - 0.0016 18.1 0.0 0.32 10.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EON99672.1 - 0.0018 17.9 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EON99672.1 - 0.0033 17.5 0.1 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EON99672.1 - 0.0035 17.6 0.1 0.26 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EON99672.1 - 0.0062 16.0 0.1 0.78 9.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EON99672.1 - 0.0098 16.0 0.1 4.6 7.4 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EON99672.1 - 0.012 15.4 3.6 0.35 10.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EON99672.1 - 0.016 13.7 0.0 2.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain HEAT PF02985.17 EON99672.1 - 0.019 14.9 1.7 48 4.4 0.0 5.0 5 0 0 5 5 4 0 HEAT repeat HEAT_2 PF13646.1 EON99672.1 - 0.02 15.1 2.9 3 8.1 0.0 4.4 3 1 0 4 4 4 0 HEAT repeats AAA_30 PF13604.1 EON99672.1 - 0.02 14.4 0.7 5.7 6.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 EON99672.1 - 0.025 14.5 0.0 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EON99672.1 - 0.052 12.4 0.1 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) LMSTEN PF07988.7 EON99672.1 - 0.062 12.5 0.2 0.24 10.7 0.1 2.0 1 0 0 1 1 1 0 LMSTEN motif Arch_ATPase PF01637.13 EON99672.1 - 0.096 12.3 0.1 22 4.6 0.0 3.0 3 0 0 3 3 2 0 Archaeal ATPase NTPase_1 PF03266.10 EON99672.1 - 0.15 11.7 0.6 16 5.1 0.1 2.7 2 0 0 2 2 2 0 NTPase DUF3584 PF12128.3 EON99672.1 - 0.17 9.1 1.4 2.7 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_24 PF13479.1 EON99672.1 - 0.46 10.0 2.7 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain PHD PF00628.24 EON99673.1 - 2e-10 40.1 1.7 2e-10 40.1 1.2 1.6 2 0 0 2 2 2 1 PHD-finger UIM PF02809.15 EON99673.1 - 0.0031 16.9 1.1 0.0085 15.5 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.1 EON99673.1 - 0.011 15.0 3.1 0.019 14.2 2.1 1.4 1 0 0 1 1 1 0 PHD-finger HrpA_pilin PF09589.5 EON99673.1 - 0.093 13.1 1.3 1.9 8.9 0.4 2.1 2 0 0 2 2 2 0 HrpA pilus formation protein zf-CW PF07496.10 EON99673.1 - 0.19 11.4 1.4 0.52 10.0 0.9 1.8 2 0 0 2 2 2 0 CW-type Zinc Finger DUF3043 PF11241.3 EON99673.1 - 0.3 10.6 9.2 0.44 10.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FAM150 PF15129.1 EON99673.1 - 0.37 10.6 2.4 3.8 7.4 0.1 2.2 2 0 0 2 2 2 0 FAM150 family C1_1 PF00130.17 EON99673.1 - 1.2 8.9 5.5 1.7 8.4 0.5 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nup54 PF13874.1 EON99674.1 - 1.6e-43 147.7 0.5 1.6e-43 147.7 0.3 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 V-SNARE_C PF12352.3 EON99674.1 - 0.015 15.3 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nucleoporin_FG PF13634.1 EON99674.1 - 0.041 14.1 17.6 0.06 13.5 12.2 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region Nbl1_Borealin_N PF10444.4 EON99674.1 - 0.11 11.9 0.7 0.56 9.6 0.1 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal FlaC_arch PF05377.6 EON99674.1 - 0.13 12.1 2.0 0.71 9.8 0.8 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.4 EON99674.1 - 0.6 8.4 6.0 0.14 10.5 0.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3552 PF12072.3 EON99674.1 - 0.92 8.6 9.1 4.1 6.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) BAR_2 PF10455.4 EON99674.1 - 1.7 7.5 7.6 0.091 11.6 1.1 1.7 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CHCH PF06747.8 EON99675.1 - 2.7e-08 33.5 11.8 4e-07 29.7 1.2 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EON99675.1 - 0.011 15.4 8.2 0.027 14.2 0.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1903 PF08991.5 EON99675.1 - 0.1 12.7 2.5 5 7.3 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1903) Pet191_N PF10203.4 EON99675.1 - 0.16 11.9 5.7 0.92 9.6 3.7 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EON99675.1 - 3.4 7.7 9.2 4.7 7.2 1.2 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Apc5 PF12862.2 EON99676.1 - 1.7e-33 114.3 5.8 4e-32 109.9 2.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 EON99676.1 - 0.00039 20.7 1.6 0.51 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EON99676.1 - 0.0017 18.2 0.1 0.041 13.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EON99676.1 - 0.0021 18.5 8.2 3.8 8.4 0.3 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EON99676.1 - 0.0034 18.0 3.6 0.092 13.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EON99676.1 - 0.0073 16.6 2.2 1.9 9.1 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EON99676.1 - 0.015 15.3 0.7 3.3 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EON99676.1 - 0.38 10.6 2.9 3.8 7.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat WSC PF01822.14 EON99677.1 - 9.2e-16 57.5 7.9 1.2e-15 57.1 5.5 1.2 1 0 0 1 1 1 1 WSC domain SUN PF03856.8 EON99678.1 - 2.3e-65 220.3 9.8 2.9e-65 220.0 6.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Herpes_capsid PF06112.6 EON99678.1 - 5.8 6.9 11.4 10 6.1 7.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Peptidase_M3 PF01432.15 EON99679.1 - 3.6e-120 402.1 0.0 5e-120 401.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EON99679.1 - 0.076 12.3 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like BNR PF02012.15 EON99680.1 - 1.5e-08 33.1 40.0 1.5 8.9 0.1 11.2 10 0 0 10 10 10 6 BNR/Asp-box repeat Rotamase_2 PF13145.1 EON99680.1 - 0.0046 17.5 0.5 0.01 16.4 0.3 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2561 PF10812.3 EON99680.1 - 0.0096 15.5 0.9 0.018 14.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) IMS PF00817.15 EON99681.1 - 1.7e-39 135.0 0.0 3.5e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family DUF4414 PF14377.1 EON99681.1 - 1.1e-16 60.6 4.3 4.6e-09 36.1 0.6 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_C PF11799.3 EON99681.1 - 1.8e-16 60.2 0.0 4.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EON99681.1 - 0.0014 18.7 0.0 0.0053 16.8 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EON99681.1 - 0.0023 17.8 0.1 0.0023 17.8 0.0 3.0 4 0 0 4 4 4 1 IMS family HHH motif DUF1805 PF08827.6 EON99681.1 - 0.007 16.1 0.0 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1805) F420_ligase PF01996.11 EON99681.1 - 0.024 13.7 0.0 0.049 12.6 0.0 1.5 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase MgtE_N PF03448.12 EON99681.1 - 0.027 14.7 2.5 5.3 7.4 0.0 3.9 3 1 1 4 4 4 0 MgtE intracellular N domain HHH_5 PF14520.1 EON99681.1 - 0.083 13.0 0.1 0.083 13.0 0.1 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 EON99681.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain ApoO PF09769.4 EON99682.1 - 1.3e-49 167.9 0.2 3e-49 166.7 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O DAGAT PF03982.8 EON99683.1 - 1.3e-100 335.8 0.0 1.8e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase ATP_bind_4 PF01902.12 EON99684.1 - 4.3e-21 75.2 0.0 4.1e-16 59.0 0.0 3.0 2 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EON99684.1 - 7e-10 38.7 0.0 1.5e-05 24.7 0.0 4.0 3 1 0 3 3 3 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 EON99684.1 - 0.32 9.4 0.0 0.49 8.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase COesterase PF00135.23 EON99685.1 - 1.9e-74 251.3 0.0 2.3e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EON99685.1 - 0.00011 21.8 0.3 0.00029 20.4 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON99685.1 - 0.0012 18.0 0.3 0.0019 17.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EON99685.1 - 0.017 14.8 0.3 0.031 14.0 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family 7tm_2 PF00002.19 EON99686.1 - 0.00013 21.1 6.0 0.00013 21.1 4.2 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EON99686.1 - 0.021 13.7 4.0 0.042 12.7 2.8 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor DC_STAMP PF07782.8 EON99686.1 - 0.16 11.6 0.2 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Mito_carr PF00153.22 EON99687.1 - 1.9e-63 210.1 0.5 8.8e-23 79.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Spore_YhaL PF14147.1 EON99687.1 - 0.02 14.3 0.7 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL RED_N PF07808.8 EON99688.1 - 9.7e-09 34.7 6.5 9.7e-09 34.7 4.5 2.8 3 1 0 3 3 3 1 RED-like protein N-terminal region zf-C2H2 PF00096.21 EON99689.1 - 4.8e-12 45.4 12.6 5.8e-06 26.3 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EON99689.1 - 4.5e-10 39.1 11.1 0.00012 22.1 3.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EON99689.1 - 1.7e-07 31.1 12.4 3.1e-06 27.1 2.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EON99689.1 - 5.3e-07 29.5 6.1 0.00034 20.6 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EON99689.1 - 1.2e-06 28.4 5.3 4.5e-05 23.4 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EON99689.1 - 0.0037 17.0 0.6 0.0037 17.0 0.4 3.1 3 1 0 3 3 3 1 C2H2-type zinc finger Elf1 PF05129.8 EON99689.1 - 2.7 7.7 5.8 8.4 6.1 0.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EON99689.1 - 4.4 7.1 7.3 7.6 6.3 2.4 2.4 1 1 1 2 2 2 0 BED zinc finger IU_nuc_hydro PF01156.14 EON99690.1 - 3.7e-78 262.9 0.1 1.2e-77 261.2 0.1 1.6 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cellulase PF00150.13 EON99691.1 - 1.8e-39 135.6 0.1 2.1e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peripla_BP_4 PF13407.1 EON99691.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Methyltransf_23 PF13489.1 EON99692.1 - 9.3e-17 61.2 0.0 1.3e-14 54.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99692.1 - 2.1e-10 40.9 0.0 1.2e-07 32.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99692.1 - 1.1e-09 38.8 0.0 4.6e-08 33.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON99692.1 - 2.8e-09 37.3 0.0 1.7e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99692.1 - 2.4e-07 30.4 0.0 2.1e-05 24.1 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON99692.1 - 0.00042 19.4 0.0 0.0021 17.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EON99692.1 - 0.00054 20.2 0.0 0.0086 16.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON99692.1 - 0.0073 15.4 0.0 0.07 12.2 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EON99692.1 - 0.0076 15.6 0.0 0.087 12.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EON99692.1 - 0.013 15.5 0.1 0.73 9.8 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EON99692.1 - 0.03 14.3 0.0 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EON99692.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Rotamase PF00639.16 EON99693.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EON99693.1 - 4e-16 59.3 0.0 5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EON99693.1 - 6e-07 29.2 1.5 1.1e-06 28.3 1.0 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EON99693.1 - 1.2e-05 25.8 0.0 1.7e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 EON99693.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 MAM domain RINGv PF12906.2 EON99694.1 - 4.3e-17 61.8 8.7 6.9e-17 61.2 6.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EON99694.1 - 0.031 14.0 8.5 0.053 13.3 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EON99694.1 - 0.04 13.5 5.6 0.064 12.9 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EON99694.1 - 0.18 11.6 1.9 0.48 10.2 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EON99694.1 - 3.4 7.3 7.2 5.6 6.6 5.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EON99694.1 - 9.2 6.3 7.2 19 5.3 5.0 1.5 1 0 0 1 1 1 0 RING-like domain Ferric_reduct PF01794.14 EON99695.1 - 2.4e-13 50.2 13.9 2.4e-13 50.2 9.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Methyltransf_23 PF13489.1 EON99696.1 - 4.6e-19 68.7 0.0 5.4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99696.1 - 1.4e-09 37.6 0.0 2.1e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99696.1 - 2.4e-08 34.5 0.0 2.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EON99696.1 - 9.1e-06 26.0 0.0 2.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99696.1 - 1.9e-05 25.0 0.0 0.00042 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON99696.1 - 3.1e-05 23.4 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EON99696.1 - 0.00025 21.0 0.0 0.014 15.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EON99696.1 - 0.0014 17.7 0.0 0.0094 15.0 0.0 2.1 2 1 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EON99696.1 - 0.0021 18.0 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EON99696.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EON99696.1 - 0.0082 15.3 0.0 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EON99696.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TauD PF02668.11 EON99697.1 - 2.2e-10 40.6 0.0 3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EON99697.1 - 0.00081 18.3 0.0 0.0022 16.9 0.0 1.6 2 0 0 2 2 2 1 CsiD AF0941-like PF14591.1 EON99698.1 - 4.9e-05 23.3 0.7 0.00013 22.0 0.5 1.7 1 0 0 1 1 1 1 AF0941-like TRI12 PF06609.8 EON99699.1 - 7.9e-06 24.3 0.8 9e-06 24.1 0.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EON99699.1 - 0.0034 16.0 6.0 0.0038 15.8 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter EIIC-GAT PF03611.9 EON99699.1 - 0.024 13.4 5.9 0.017 13.8 1.8 1.8 1 1 1 2 2 2 0 PTS system sugar-specific permease component DUF3087 PF11286.3 EON99699.1 - 0.024 13.8 2.3 0.029 13.6 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) MFS_1 PF07690.11 EON99699.1 - 0.044 12.4 13.2 0.056 12.1 9.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily tRNA-synt_1d PF00750.14 EON99700.1 - 1.4e-81 274.0 2.6 2.6e-81 273.2 1.8 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EON99700.1 - 6.3e-30 103.5 0.5 1.3e-29 102.5 0.4 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EON99700.1 - 0.0028 18.1 0.0 0.0071 16.8 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain MFS_1 PF07690.11 EON99701.1 - 0.095 11.3 0.5 0.11 11.2 0.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.11 EON99702.1 - 2.1e-31 108.9 24.2 2.1e-31 108.9 16.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON99702.1 - 2.6e-30 105.4 27.3 6.1e-30 104.1 18.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter PIRT PF15099.1 EON99702.1 - 0.076 12.2 0.3 0.076 12.2 0.2 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Peptidase_A8 PF01252.13 EON99702.1 - 6.7 6.3 9.2 0.87 9.1 2.6 2.3 2 1 0 2 2 2 0 Signal peptidase (SPase) II NPP1 PF05630.6 EON99703.1 - 1.3e-44 152.4 0.4 1.4e-44 152.2 0.3 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Sugar_tr PF00083.19 EON99704.1 - 4.7e-36 124.3 16.6 5.4e-36 124.1 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF983 PF06170.7 EON99704.1 - 0.053 13.6 0.6 0.17 11.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Ank_2 PF12796.2 EON99705.1 - 4.7e-50 167.8 0.0 3.5e-17 62.5 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EON99705.1 - 1.1e-35 119.5 0.2 3.9e-09 35.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EON99705.1 - 2.6e-27 94.6 3.9 2e-08 34.5 0.1 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EON99705.1 - 5.5e-27 93.1 0.3 3.7e-09 36.5 0.0 4.6 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EON99705.1 - 1.2e-25 87.0 0.5 1.5e-08 34.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF962 PF06127.6 EON99705.1 - 3.2 7.6 5.7 0.71 9.8 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Aldo_ket_red PF00248.16 EON99706.1 - 9.7e-53 178.8 0.0 1.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_19 PF12844.2 EON99706.1 - 0.14 12.2 0.0 7.3 6.7 0.0 3.0 2 1 1 3 3 3 0 Helix-turn-helix domain RNA_POL_M_15KD PF02150.11 EON99707.1 - 1.2e-11 44.0 2.9 1.2e-11 44.0 2.0 2.0 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EON99707.1 - 0.002 18.0 4.4 0.28 11.1 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EON99707.1 - 0.066 13.0 5.4 0.11 12.3 2.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon eIF3g PF12353.3 EON99707.1 - 0.077 12.9 2.7 0.22 11.4 1.8 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G OrfB_Zn_ribbon PF07282.6 EON99707.1 - 0.08 12.6 2.4 1.1 8.9 0.7 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 EON99707.1 - 0.89 9.3 4.8 0.41 10.3 0.8 2.1 2 0 0 2 2 2 0 Nudix N-terminal IBR PF01485.16 EON99707.1 - 1.8 8.4 6.9 1.4 8.8 2.3 2.1 1 1 1 2 2 2 0 IBR domain BTB PF00651.26 EON99708.1 - 1.6e-06 28.0 0.0 8.7e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain NeA_P2 PF12312.3 EON99708.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein GST_C PF00043.20 EON99709.1 - 3.3e-08 33.3 0.0 3.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EON99709.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dehalogenase PF13486.1 EON99709.1 - 0.087 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Peptidase_M24 PF00557.19 EON99710.1 - 2.4e-10 40.3 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_L14 PF00238.14 EON99711.1 - 4.2e-41 139.5 1.8 4.7e-41 139.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS_3 PF08447.6 EON99711.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 PAS fold PALP PF00291.20 EON99712.1 - 3.2e-60 203.9 0.1 4.1e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EON99712.1 - 4.7e-10 39.1 0.0 2.1e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain adh_short PF00106.20 EON99713.1 - 7.3e-15 55.2 1.0 7.5e-15 55.2 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EON99713.1 - 8.7e-08 32.0 0.1 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON99713.1 - 0.0088 15.4 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EON99713.1 - 0.063 12.1 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EON99713.1 - 0.13 12.2 0.2 0.61 10.0 0.2 2.0 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 EON99714.1 - 1.4e-105 353.5 24.6 1.5e-105 353.3 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EON99714.1 - 3.9e-33 114.6 35.1 3.7e-22 78.5 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YqfD PF06898.6 EON99714.1 - 0.13 10.9 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD SRPRB PF09439.5 EON99715.1 - 3.2e-29 101.4 0.0 1.1e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EON99715.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EON99715.1 - 0.0005 20.1 0.1 0.00082 19.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EON99715.1 - 0.0017 17.6 0.0 0.021 14.0 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.14 EON99715.1 - 0.0018 17.7 0.4 1.6 8.1 0.0 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EON99715.1 - 0.0026 16.9 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EON99715.1 - 0.0051 16.6 0.1 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EON99715.1 - 0.008 15.3 0.1 0.029 13.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EON99715.1 - 0.0092 16.1 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EON99715.1 - 0.012 15.0 0.0 0.07 12.5 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EON99715.1 - 0.015 14.4 0.0 0.034 13.2 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EON99715.1 - 0.016 14.7 0.2 0.086 12.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EON99715.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EON99715.1 - 0.019 14.5 0.1 1.4 8.3 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EON99715.1 - 0.032 13.2 0.0 0.067 12.1 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 EON99715.1 - 0.041 13.4 0.2 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EON99715.1 - 0.062 13.7 0.0 0.27 11.7 0.0 2.1 3 0 0 3 3 2 0 Miro-like protein AAA_5 PF07728.9 EON99715.1 - 0.067 12.9 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EON99715.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EON99715.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EON99715.1 - 0.13 11.7 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2828 PF11443.3 EON99716.1 - 5e-169 562.9 0.0 6.7e-169 562.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) E1-E2_ATPase PF00122.15 EON99717.1 - 1.4e-62 210.7 0.0 7.3e-47 159.3 0.0 2.1 1 1 1 2 2 2 2 E1-E2 ATPase FAD_binding_4 PF01565.18 EON99719.1 - 5.4e-27 93.9 3.6 8.1e-27 93.3 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON99719.1 - 9.6e-08 31.8 0.0 2.5e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Berberine and berberine like Prefoldin_2 PF01920.15 EON99720.1 - 0.0086 15.8 3.1 1.8 8.3 0.1 4.1 4 0 0 4 4 4 1 Prefoldin subunit DUF1529 PF07485.6 EON99720.1 - 0.12 12.1 1.1 28 4.4 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1259) DivIC PF04977.10 EON99720.1 - 0.23 10.9 6.2 8.4 5.9 0.3 3.4 2 0 0 2 2 2 0 Septum formation initiator DUF948 PF06103.6 EON99720.1 - 0.39 10.6 2.5 3.6 7.5 0.1 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) dCMP_cyt_deam_1 PF00383.17 EON99721.1 - 5.4e-07 29.1 0.0 9.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_S8 PF00082.17 EON99722.1 - 2.2e-48 164.8 0.0 8e-48 163.0 0.0 1.9 2 1 0 2 2 2 1 Subtilase family PA PF02225.17 EON99722.1 - 8.7e-13 47.8 0.1 3.1e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EON99722.1 - 6.9e-12 45.7 0.0 1.7e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) FlgD_ig PF13860.1 EON99722.1 - 0.03 14.0 0.0 0.086 12.5 0.0 1.8 1 0 0 1 1 1 0 FlgD Ig-like domain CesT PF05932.8 EON99723.1 - 0.05 13.4 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family WD40 PF00400.27 EON99724.1 - 8.5e-61 199.8 19.5 7.4e-11 41.4 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EON99724.1 - 7.2e-13 48.0 1.7 1.4e-12 47.1 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EON99724.1 - 1.2e-09 37.5 0.4 1.2e-09 37.5 0.3 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EON99724.1 - 2.2e-05 22.7 3.7 0.18 9.9 0.1 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EON99724.1 - 0.025 14.0 0.5 0.85 9.0 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain PRANC PF09372.5 EON99724.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Cofilin_ADF PF00241.15 EON99725.1 - 3.1e-19 69.1 0.0 1.6e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EON99726.1 - 1.6e-70 232.8 2.9 4.6e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FAD_oxidored PF12831.2 EON99727.1 - 1.8e-73 248.0 0.0 2.4e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Arginase PF00491.16 EON99728.1 - 1.9e-28 99.5 0.0 2.3e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family SET PF00856.23 EON99729.1 - 4.8e-08 33.4 0.0 2.2e-07 31.3 0.0 2.2 2 1 0 2 2 2 1 SET domain RALF PF05498.6 EON99730.1 - 0.13 13.1 1.6 0.24 12.2 1.1 1.5 1 0 0 1 1 1 0 Rapid ALkalinization Factor (RALF) HeLo PF14479.1 EON99731.1 - 1.7e-07 31.2 0.5 0.0022 17.7 0.0 2.8 1 1 1 2 2 2 2 Prion-inhibition and propagation COesterase PF00135.23 EON99732.1 - 5.3e-98 329.0 0.0 7.4e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EON99732.1 - 2e-06 27.5 0.1 5.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EON99732.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DPBB_1 PF03330.13 EON99733.1 - 1e-07 31.8 0.1 8.2e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EON99733.1 - 0.0034 17.1 0.7 0.0049 16.6 0.5 1.2 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.15 EON99733.1 - 0.0074 15.9 0.3 0.026 14.2 0.2 2.0 1 0 0 1 1 1 1 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EON99733.1 - 0.043 13.4 0.1 0.074 12.6 0.1 1.4 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Aldo_ket_red PF00248.16 EON99734.1 - 5.3e-33 114.0 0.0 6.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.15 EON99735.1 - 1.5e-82 277.1 0.4 1.9e-82 276.7 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EON99735.1 - 2e-08 33.9 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EON99735.1 - 3.8e-08 32.8 0.3 0.00055 19.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EON99735.1 - 0.011 15.3 0.2 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) UCR_Fe-S_N PF10399.4 EON99735.1 - 0.076 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NIR_SIR PF01077.17 EON99736.1 - 6e-30 103.6 0.0 1.4e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EON99736.1 - 1.6e-27 96.7 0.1 2.8e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EON99736.1 - 3.3e-17 62.6 5.1 7.5e-16 58.3 0.7 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EON99736.1 - 1.6e-15 56.8 0.8 2.9e-12 46.4 1.6 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 EON99736.1 - 1e-13 50.9 0.0 1.7e-10 40.5 0.0 2.8 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EON99736.1 - 1.3e-11 43.9 0.1 7.2e-11 41.5 0.0 2.3 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EON99736.1 - 6.7e-09 35.2 0.0 1.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EON99736.1 - 2.8e-08 34.0 0.1 7.5e-05 22.8 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON99736.1 - 2.3e-05 24.2 1.1 1 9.1 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EON99736.1 - 0.00068 18.8 0.1 0.092 11.7 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 EON99736.1 - 0.0029 16.5 0.0 0.0065 15.4 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EON99736.1 - 0.024 14.6 0.4 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Glyco_hydro_3 PF00933.16 EON99739.1 - 6e-65 219.1 0.0 8.3e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON99739.1 - 1.3e-59 201.4 0.0 2.1e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EON99739.1 - 1.6e-22 79.2 0.8 4.5e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 Fibronectin type III-like domain DUF11 PF01345.13 EON99739.1 - 3.6 7.6 9.1 0.43 10.6 2.2 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF11 DUF2456 PF10445.4 EON99740.1 - 1.3e-16 60.2 0.8 1.3e-16 60.2 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) PXA PF02194.10 EON99741.1 - 1.9e-54 184.0 1.2 2.7e-54 183.5 0.1 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EON99741.1 - 5.3e-31 107.0 0.0 2e-30 105.1 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EON99741.1 - 7.3e-21 74.0 0.4 3.8e-20 71.7 0.3 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EON99741.1 - 1.3e-08 34.9 0.0 4.4e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain A_deaminase PF00962.17 EON99742.1 - 1.5e-71 241.0 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Abhydrolase_6 PF12697.2 EON99742.1 - 2e-18 67.1 0.1 4e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON99742.1 - 0.0012 18.5 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EON99742.1 - 0.036 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EON99742.1 - 0.037 13.5 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.7 EON99742.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) adh_short PF00106.20 EON99743.1 - 1.6e-23 83.4 0.4 2.3e-23 82.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99743.1 - 1.9e-23 83.4 0.0 2.3e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99743.1 - 1.5e-11 44.2 0.1 2e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EON99743.1 - 3.2e-05 23.5 0.1 5.9e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON99743.1 - 0.00031 19.5 0.5 0.00044 19.0 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Lactonase PF10282.4 EON99744.1 - 2.3e-18 66.4 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_2_C PF02836.12 EON99745.1 - 1.3e-100 336.1 0.1 2.3e-100 335.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EON99745.1 - 6e-48 163.2 0.0 9.5e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EON99745.1 - 3.1e-34 117.9 0.1 5.8e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EON99745.1 - 8.7e-14 51.9 0.1 2.1e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EON99745.1 - 0.023 14.9 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Abhydrolase_3 PF07859.8 EON99746.1 - 0.0064 16.0 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ceramidase_alk PF04734.8 EON99747.1 - 1.8e-277 921.7 0.0 2e-277 921.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase PTCB-BRCT PF12738.2 EON99748.1 - 7.8e-31 105.7 0.3 2.4e-19 68.9 0.1 4.7 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EON99748.1 - 7e-21 74.1 0.1 3.1e-08 33.6 0.0 5.6 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain ADH_N PF08240.7 EON99749.1 - 5.1e-26 90.5 3.8 1.1e-25 89.5 2.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON99749.1 - 5.8e-14 51.7 0.0 2.3e-13 49.8 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Lactamase_B_2 PF12706.2 EON99750.1 - 1.8e-40 138.6 0.1 2.2e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EON99750.1 - 2.8e-09 36.8 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3756 PF12581.3 EON99750.1 - 0.019 14.6 0.4 0.56 9.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Lactamase_B PF00753.22 EON99750.1 - 0.75 9.4 5.6 1.9 8.0 3.7 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glucosamine_iso PF01182.15 EON99751.1 - 6.2e-24 84.8 0.0 9.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MR_MLE_C PF13378.1 EON99752.1 - 3.4e-18 65.6 0.0 8.8e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EON99752.1 - 2.1e-12 47.3 0.0 7e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EON99752.1 - 0.0033 17.3 0.2 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UPF0150 PF03681.10 EON99752.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) MAAL_C PF07476.6 EON99752.1 - 0.055 12.3 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus ESCRT-II PF05871.7 EON99753.1 - 1.9e-46 157.4 0.0 4.3e-46 156.2 0.0 1.6 1 1 0 1 1 1 1 ESCRT-II complex subunit Complex1_LYR PF05347.10 EON99754.1 - 0.033 14.0 0.3 0.056 13.2 0.2 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EON99754.1 - 0.044 13.9 0.3 0.067 13.4 0.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like FGGY_C PF02782.11 EON99756.1 - 4.9e-74 248.2 1.2 9.1e-74 247.3 0.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EON99756.1 - 5.8e-63 212.4 0.0 8e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Amidohydro_4 PF13147.1 EON99757.1 - 4.5e-18 66.2 0.0 2e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EON99757.1 - 1.4e-08 34.4 0.0 2.9e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.15 EON99757.1 - 2.7e-08 33.8 0.0 7.4e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EON99757.1 - 0.00043 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Nramp PF01566.13 EON99758.1 - 9.5e-92 307.5 15.0 9.5e-92 307.5 10.4 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Glyco_hydro_3 PF00933.16 EON99759.1 - 7.3e-57 192.6 0.0 1.1e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EON99759.1 - 3.2e-05 23.5 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EON99759.1 - 0.0091 16.0 0.0 0.037 14.0 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fe_hyd_SSU PF02256.12 EON99759.1 - 0.026 14.5 0.0 3.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit Acetyltransf_7 PF13508.1 EON99759.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexokinase_1 PF00349.16 EON99760.1 - 6.6e-32 110.5 0.0 1.2e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EON99760.1 - 2.4e-29 102.2 0.0 1.5e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Glyco_hydro_61 PF03443.9 EON99761.1 - 1.1e-83 280.3 0.2 1.8e-83 279.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MGC-24 PF05283.6 EON99761.1 - 4.9 6.8 16.9 10 5.8 11.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) His_Phos_1 PF00300.17 EON99762.1 - 1.1e-15 58.0 0.0 2.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.20 EON99763.1 - 4.2e-17 62.5 0.6 6.9e-17 61.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99763.1 - 3.7e-11 43.0 0.2 5.7e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EON99763.1 - 0.0013 17.7 0.1 0.0027 16.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein E2R135 PF11570.3 EON99763.1 - 0.0035 17.4 1.0 0.0057 16.7 0.7 1.3 1 0 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 Paramyxo_C PF01692.13 EON99763.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Chromo_shadow PF01393.14 EON99764.1 - 3.7e-14 52.2 0.1 8.5e-13 47.9 0.0 2.5 2 1 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EON99764.1 - 1.1e-13 50.5 0.4 1.1e-13 50.5 0.3 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.8 EON99764.1 - 9.4 3.8 15.8 12 3.5 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Gryzun PF07919.7 EON99765.1 - 3.5e-75 253.4 0.1 3.9e-75 253.2 0.1 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 EON99765.1 - 0.015 15.0 0.0 0.048 13.4 0.0 1.8 1 1 0 1 1 1 0 Gryzun, putative Golgi trafficking BCS1_N PF08740.6 EON99766.1 - 7.9e-55 185.3 3.2 7.9e-55 185.3 2.2 2.5 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EON99766.1 - 1.2e-17 64.3 0.0 2.1e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EON99766.1 - 0.00033 20.1 0.0 0.0011 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EON99766.1 - 0.00041 19.4 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EON99766.1 - 0.00082 19.1 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EON99766.1 - 0.0015 18.5 0.3 0.0065 16.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EON99766.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EON99766.1 - 0.051 14.3 0.0 0.051 14.3 0.0 3.3 3 2 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EON99766.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EON99766.1 - 0.13 12.2 2.6 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SET PF00856.23 EON99766.1 - 1.6 9.0 5.5 1.6 9.0 2.3 2.2 2 0 0 2 2 2 0 SET domain PAP1 PF08601.5 EON99767.1 - 6.1e-69 233.3 14.6 6.1e-69 233.3 10.2 2.5 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EON99767.1 - 1e-09 38.1 6.9 2.3e-09 37.0 4.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EON99767.1 - 0.007 16.1 9.6 0.018 14.8 6.3 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EON99767.1 - 0.0071 16.6 7.0 0.015 15.5 4.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor dsrm PF00035.20 EON99767.1 - 0.064 13.8 0.2 0.15 12.6 0.2 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif MbeD_MobD PF04899.7 EON99767.1 - 0.094 12.6 0.4 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 MbeD/MobD like Adeno_PIX PF03955.9 EON99767.1 - 0.14 12.6 1.0 0.4 11.2 0.7 1.7 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) SlyX PF04102.7 EON99767.1 - 0.26 11.6 1.5 0.81 10.1 0.5 2.2 1 1 1 2 2 2 0 SlyX Sigma70_ner PF04546.8 EON99767.1 - 1.6 8.3 10.3 3.6 7.1 7.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NAM-associated PF14303.1 EON99767.1 - 6.8 6.9 24.3 0.078 13.2 10.0 2.5 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Epimerase PF01370.16 EON99768.1 - 2.9e-25 89.1 0.0 4e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON99768.1 - 1.3e-12 47.0 0.0 1.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EON99768.1 - 3e-11 43.5 0.0 5.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EON99768.1 - 9e-10 37.8 0.0 1.9e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EON99768.1 - 9e-10 37.9 0.0 1.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EON99768.1 - 1.3e-08 35.0 0.0 1.9e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EON99768.1 - 3.4e-07 29.4 0.0 1.4e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EON99768.1 - 2.3e-06 27.3 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 EON99769.1 - 1.6e-49 164.1 15.3 1.9e-11 43.4 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EON99769.1 - 1.8e-07 31.0 10.7 0.0021 17.8 0.1 4.1 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EON99769.1 - 0.0055 14.5 2.7 0.3 8.8 0.0 2.1 2 0 0 2 2 2 2 IKI3 family Kelch_6 PF13964.1 EON99769.1 - 0.028 14.6 0.1 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 EON99769.1 - 0.032 14.3 0.8 0.35 11.0 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.20 EON99769.1 - 0.044 13.3 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Spermine_synth PF01564.12 EON99770.1 - 6.4e-07 28.5 0.0 1.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EON99770.1 - 1.7e-05 24.8 0.1 3.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EON99770.1 - 0.002 17.8 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99770.1 - 0.045 14.2 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EON99770.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PEMT PF04191.8 EON99771.1 - 1.2e-31 108.9 2.2 1.8e-31 108.4 1.5 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.6 EON99772.1 - 2.1e-40 137.9 0.0 2.1e-40 137.9 0.0 3.3 3 1 1 4 4 4 1 RXT2-like, N-terminal UvrD-helicase PF00580.16 EON99774.1 - 3.5e-64 217.0 1.3 5.7e-62 209.8 0.1 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EON99774.1 - 1.7e-50 172.5 1.6 2.5e-50 171.9 1.1 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EON99774.1 - 8.9e-12 44.6 0.3 2e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EON99774.1 - 4.2e-06 26.4 0.2 0.0013 18.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EON99774.1 - 0.00095 18.7 0.1 0.054 12.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PKI PF02827.11 EON99774.1 - 0.049 13.7 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor AAA_10 PF12846.2 EON99774.1 - 0.075 12.4 1.1 5.3 6.3 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain DUF2937 PF11157.3 EON99775.1 - 0.11 11.8 4.2 1.4 8.2 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4078 PF13300.1 EON99776.1 - 1.1e-29 102.4 20.9 1.1e-29 102.4 14.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) TPR_MLP1_2 PF07926.7 EON99776.1 - 0.011 15.5 8.9 1 9.0 8.5 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein NTP_transferase PF00483.18 EON99777.1 - 2.8e-48 164.3 0.0 5.5e-48 163.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EON99777.1 - 2.1e-16 58.5 13.2 2e-09 36.5 1.4 3.9 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EON99777.1 - 1.5e-10 41.3 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EON99777.1 - 8e-07 28.5 1.0 8e-07 28.5 0.7 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EON99777.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 EON99777.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LCM PF04072.9 EON99778.1 - 5.1e-38 130.4 0.0 6.2e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2065 PF09838.4 EON99778.1 - 0.035 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) BSD PF03909.12 EON99779.1 - 4.6e-18 64.7 0.2 1e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EON99779.1 - 0.083 12.6 4.6 0.026 14.2 0.7 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) COPI_C PF06957.6 EON99779.1 - 0.096 11.2 0.7 0.17 10.4 0.5 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Rad10 PF03834.9 EON99780.1 - 7e-30 102.5 0.0 1.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EON99780.1 - 9.5e-05 22.5 1.7 9.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain SART-1 PF03343.8 EON99780.1 - 0.034 12.4 1.2 0.042 12.2 0.8 1.1 1 0 0 1 1 1 0 SART-1 family Ion_trans_2 PF07885.11 EON99781.1 - 2.1e-30 104.2 33.5 1.4e-18 66.3 5.3 3.2 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EON99781.1 - 3.3 6.9 19.4 0.033 13.4 2.3 2.8 2 1 0 2 2 2 0 Ion transport protein SieB PF14163.1 EON99781.1 - 5.2 6.6 6.1 62 3.1 0.0 3.2 2 1 1 3 3 3 0 Superinfection exclusion protein B UCR_hinge PF02320.11 EON99782.1 - 6.3e-28 96.5 7.6 1e-27 95.8 5.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Myc_N PF01056.13 EON99782.1 - 0.047 12.8 12.1 0.053 12.6 8.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 EON99782.1 - 0.42 8.5 15.2 0.46 8.4 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EON99782.1 - 0.49 8.4 7.7 0.55 8.2 5.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 EON99782.1 - 0.52 8.7 25.1 0.57 8.5 17.4 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EON99782.1 - 0.85 8.8 22.7 0.89 8.7 15.7 1.0 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 EON99782.1 - 1.1 7.4 21.0 1.3 7.3 14.6 1.0 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.2 EON99782.1 - 1.7 8.1 9.8 2 7.8 6.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CobT PF06213.7 EON99782.1 - 1.7 7.6 21.7 2.1 7.4 15.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.10 EON99782.1 - 1.8 7.0 7.4 1.9 7.0 5.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 EON99782.1 - 2.2 7.5 21.0 2.6 7.3 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 EON99782.1 - 2.3 6.2 10.9 2.5 6.1 7.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T PF15511.1 EON99782.1 - 4.6 6.3 18.4 5.3 6.1 12.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Tim54 PF11711.3 EON99782.1 - 6.1 5.3 10.4 7 5.1 7.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Bap31 PF05529.7 EON99782.1 - 6.2 6.2 5.2 7.3 5.9 3.6 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Nop14 PF04147.7 EON99782.1 - 6.2 4.6 26.0 6.8 4.4 18.0 1.0 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.4 EON99782.1 - 8.3 5.0 12.1 9.1 4.9 8.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Ndc80_HEC PF03801.8 EON99784.1 - 2.3e-60 202.6 0.4 2.3e-60 202.6 0.3 1.6 2 0 0 2 2 2 1 HEC/Ndc80p family Spc7 PF08317.6 EON99784.1 - 0.00034 19.3 30.2 0.016 13.9 10.0 2.7 2 0 0 2 2 2 2 Spc7 kinetochore protein Anth_Ig PF05587.8 EON99784.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Anthrax receptor extracellular domain Reo_sigmaC PF04582.7 EON99784.1 - 0.89 8.6 3.8 1.1 8.3 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EON99784.1 - 2.6 8.3 11.1 7.6 6.8 0.7 3.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EON99784.1 - 5.2 6.8 24.0 0.072 12.8 0.5 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EON99784.1 - 7.4 6.3 39.6 6.8 6.4 11.9 3.6 2 2 0 2 2 2 0 Autophagy protein 16 (ATG16) Dak2 PF02734.12 EON99784.1 - 7.7 6.1 8.4 3 7.4 1.1 2.7 3 0 0 3 3 3 0 DAK2 domain AMP-binding PF00501.23 EON99785.1 - 3.8e-77 259.4 0.0 5.3e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 EON99786.1 - 4.5e-06 26.5 2.4 5.5e-06 26.2 1.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain COX7C PF02935.11 EON99786.1 - 0.026 14.3 1.3 0.44 10.3 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF3566 PF12089.3 EON99786.1 - 0.16 11.9 3.4 0.28 11.2 2.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) SirB PF04247.7 EON99786.1 - 0.24 11.1 4.6 0.29 10.8 2.2 1.8 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF3382 PF11862.3 EON99786.1 - 0.67 9.8 6.3 0.18 11.7 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF3147 PF11345.3 EON99786.1 - 1 9.4 6.4 20 5.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3147) Fig1 PF12351.3 EON99786.1 - 2.6 7.8 8.4 4.9 6.9 5.9 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Pyridox_oxidase PF01243.15 EON99787.1 - 0.00043 20.2 0.0 0.037 14.0 0.0 2.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 EON99787.1 - 0.00066 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EON99787.1 - 0.0074 16.3 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_4 PF01565.18 EON99788.1 - 8.3e-17 60.9 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EON99789.1 - 5.3e-75 251.8 0.0 6e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0052 PF01933.13 EON99789.1 - 0.057 12.7 0.0 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0052 MFS_1 PF07690.11 EON99790.1 - 3.5e-33 114.7 55.0 4.1e-29 101.3 27.9 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EON99790.1 - 1.5e-14 53.1 15.2 2.3e-14 52.5 3.0 2.7 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) GSDH PF07995.6 EON99792.1 - 1e-08 34.6 0.0 2.9e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EON99792.1 - 0.002 17.5 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Dmrt1 PF12374.3 EON99792.1 - 0.66 10.3 11.8 2.9 8.2 1.7 2.8 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Pex14_N PF04695.8 EON99793.1 - 0.064 13.3 4.4 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EON99793.1 - 1.6 6.8 4.4 2 6.5 3.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_A_type_inc PF04508.7 EON99793.1 - 3.2 7.7 7.9 0.41 10.5 0.7 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Pex19 PF04614.7 EON99795.1 - 0.059 12.9 1.9 0.094 12.3 1.3 1.3 1 0 0 1 1 1 0 Pex19 protein family Utp14 PF04615.8 EON99796.1 - 2.2e-181 604.7 52.0 2.2e-181 604.7 36.0 2.6 1 1 1 2 2 2 1 Utp14 protein FAD_binding_3 PF01494.14 EON99797.1 - 9e-16 57.8 6.7 3e-14 52.8 4.6 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EON99797.1 - 6.4e-05 22.8 1.3 0.00044 20.2 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EON99797.1 - 0.00065 18.6 0.0 0.0014 17.5 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.19 EON99797.1 - 0.0082 15.0 2.7 0.012 14.4 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EON99797.1 - 0.0084 16.4 1.2 0.089 13.2 1.4 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON99797.1 - 0.0088 14.9 0.8 0.019 13.8 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EON99797.1 - 0.033 14.0 1.9 0.07 12.9 0.8 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EON99797.1 - 0.12 12.1 0.8 1.2 8.8 0.6 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EON99797.1 - 0.19 11.7 0.3 0.72 9.8 0.2 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON99797.1 - 0.45 9.3 1.7 0.62 8.8 1.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A polyprenyl_synt PF00348.12 EON99798.1 - 3.3e-15 55.6 0.2 7.1e-15 54.5 0.1 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EON99798.1 - 9.1e-05 21.8 1.5 0.00014 21.2 0.5 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain RRM_1 PF00076.17 EON99799.1 - 1.2e-22 79.3 0.0 1e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EON99799.1 - 5.5e-16 58.3 0.0 7.1e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99799.1 - 1.8e-10 40.4 0.0 6.6e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 EON99800.1 - 4.7e-20 70.9 12.1 9.7e-20 69.8 8.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EON99800.1 - 2.1e-11 43.2 0.1 8e-11 41.4 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EON99800.1 - 2.5e-07 30.2 6.9 2.5e-07 30.2 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EON99800.1 - 8.3e-07 28.9 0.0 2.2e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EON99800.1 - 3.5e-06 26.7 0.1 8.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EON99800.1 - 3.5e-06 26.4 3.1 4.4e-06 26.0 2.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EON99800.1 - 6.5e-05 22.6 9.2 6.5e-05 22.6 6.4 2.0 2 0 0 2 2 2 1 Ring finger domain SET_assoc PF11767.3 EON99800.1 - 0.0021 17.3 0.4 0.0054 16.0 0.0 1.8 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated FYVE_2 PF02318.11 EON99800.1 - 0.0023 17.8 4.0 0.0023 17.8 2.7 2.2 1 1 1 2 2 2 1 FYVE-type zinc finger zf-C3HC4 PF00097.20 EON99800.1 - 0.0036 16.9 9.8 0.0036 16.9 6.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EON99800.1 - 0.0043 16.7 3.6 0.014 15.1 2.5 2.0 1 0 0 1 1 1 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EON99800.1 - 0.0051 16.5 5.0 0.012 15.3 3.5 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.1 EON99800.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF576 PF04507.7 EON99800.1 - 0.024 13.5 1.4 0.042 12.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF576 DUF1289 PF06945.8 EON99800.1 - 0.047 13.1 2.2 0.15 11.5 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) zf-RING_5 PF14634.1 EON99800.1 - 0.053 13.2 10.1 0.14 11.9 7.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Rad50_zn_hook PF04423.9 EON99800.1 - 0.074 12.5 0.9 2.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EON99800.1 - 0.12 11.9 11.4 0.22 11.0 3.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EON99800.1 - 0.18 11.6 3.2 0.45 10.3 0.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.16 EON99800.1 - 1.9 8.4 12.0 0.16 11.9 4.7 1.9 2 1 0 2 2 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 EON99800.1 - 2.7 7.9 12.9 26 4.7 8.3 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EON99800.1 - 3.8 7.6 17.0 0.11 12.4 7.1 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyr_redox_2 PF07992.9 EON99801.1 - 1.8e-35 122.6 1.9 2.6e-33 115.6 1.3 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 EON99801.1 - 7.2e-18 64.9 0.1 1.8e-17 63.7 0.0 1.7 2 0 0 2 2 1 1 Rhodanese-like domain Pyr_redox PF00070.22 EON99801.1 - 7.7e-18 64.6 2.3 2.3e-15 56.7 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EON99801.1 - 6.2e-14 51.9 0.4 2.7e-13 49.9 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.1 EON99801.1 - 4.9e-10 39.2 0.8 0.0011 18.9 0.0 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EON99801.1 - 4.6e-07 30.0 0.1 7.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EON99801.1 - 9.5e-06 24.7 7.7 0.076 11.8 0.0 4.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EON99801.1 - 0.00032 19.3 0.2 0.28 9.6 0.0 3.3 3 1 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 EON99801.1 - 0.00063 18.7 3.3 0.15 10.9 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 EON99801.1 - 0.00064 19.9 0.3 0.63 10.3 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.1 EON99801.1 - 0.0011 17.9 0.0 0.0027 16.6 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EON99801.1 - 0.018 14.1 0.2 6.9 5.6 0.1 2.8 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.7 EON99801.1 - 0.046 12.6 0.5 3.9 6.2 0.0 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EON99801.1 - 0.07 11.9 0.3 0.39 9.5 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_3 PF07859.8 EON99803.1 - 1.7e-40 138.8 0.1 1.3e-30 106.6 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EON99803.1 - 1.3e-12 47.0 0.0 1.5e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EON99803.1 - 2.6e-05 23.9 0.0 5.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EON99803.1 - 0.00011 21.1 0.4 0.049 12.3 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Glyco_hydro_81 PF03639.8 EON99804.1 - 6.8e-211 701.9 13.7 8.1e-211 701.6 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Glyco_hydro_31 PF01055.21 EON99805.1 - 1.8e-116 389.5 0.5 2.2e-116 389.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EON99805.1 - 2.4e-14 52.9 0.0 1.2e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like ubiquitin PF00240.18 EON99806.1 - 4.5e-133 432.8 23.5 6.8e-33 111.8 0.6 4.4 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EON99806.1 - 1.9e-75 248.5 21.1 2.7e-18 65.4 0.5 4.5 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like BRAP2 PF07576.7 EON99806.1 - 9.4e-21 73.4 0.0 1.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Ubiquitin_2 PF14560.1 EON99806.1 - 9.6e-21 73.8 11.2 0.00089 19.4 0.1 5.1 4 0 0 4 4 4 4 Ubiquitin-like domain zf-UBP PF02148.14 EON99806.1 - 1.1e-17 63.8 7.7 2.8e-17 62.5 5.3 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rad60-SLD_2 PF13881.1 EON99806.1 - 3.9e-12 46.0 3.9 0.026 14.4 0.0 4.8 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EON99806.1 - 1.3e-09 38.1 10.9 0.11 12.6 0.2 5.0 2 1 2 5 5 5 4 DUF2407 ubiquitin-like domain zf-RING_2 PF13639.1 EON99806.1 - 6.1e-09 35.5 10.2 6.1e-09 35.5 7.1 2.0 2 0 0 2 2 1 1 Ring finger domain DUF2870 PF11069.3 EON99806.1 - 1.7e-07 31.1 3.7 4.5 7.3 0.0 5.5 6 0 0 6 6 4 1 Protein of unknown function (DUF2870) zf-RING_5 PF14634.1 EON99806.1 - 8.2e-05 22.2 7.1 8.2e-05 22.2 4.9 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Plexin_cytopl PF08337.7 EON99806.1 - 0.00014 20.3 7.3 4.8 5.3 0.0 5.4 5 0 0 5 5 5 1 Plexin cytoplasmic RasGAP domain zf-C3HC4 PF00097.20 EON99806.1 - 0.00023 20.7 8.4 0.00053 19.5 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TUG-UBL1 PF11470.3 EON99806.1 - 0.0011 18.8 5.9 25 4.8 0.0 4.3 4 0 0 4 4 4 0 GLUT4 regulating protein TUG zf-C3HC4_2 PF13923.1 EON99806.1 - 0.0015 18.5 9.2 0.0015 18.5 6.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EON99806.1 - 0.0026 17.3 6.7 0.0026 17.3 4.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EON99806.1 - 0.0074 16.3 5.8 0.0074 16.3 4.0 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EON99806.1 - 0.0076 15.9 2.0 0.0076 15.9 1.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EON99806.1 - 0.015 15.0 3.1 0.036 13.8 2.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EON99806.1 - 0.036 13.9 6.4 0.089 12.6 4.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FlgD_ig PF13860.1 EON99806.1 - 0.051 13.3 6.5 68 3.2 0.0 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain FlaC_arch PF05377.6 EON99806.1 - 0.09 12.6 0.4 0.62 10.0 0.3 2.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SBDS_C PF09377.5 EON99806.1 - 0.12 12.0 0.9 0.32 10.7 0.6 1.7 1 1 0 1 1 1 0 SBDS protein C-terminal domain DUF2031 PF09592.5 EON99806.1 - 0.17 11.0 4.5 0.35 9.9 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) FERM_N PF09379.5 EON99806.1 - 0.26 11.3 3.9 2.1e+02 2.0 0.0 4.9 4 0 0 4 4 4 0 FERM N-terminal domain GABP-alpha PF11620.3 EON99806.1 - 4.4 7.3 6.3 1.5e+02 2.4 0.0 3.9 4 0 0 4 4 4 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EON99806.1 - 5.2 7.1 29.1 14 5.7 1.2 4.6 4 0 0 4 4 4 0 Tash protein PEST motif BHD_3 PF10405.4 EON99807.1 - 2.3e-23 81.7 0.1 3.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EON99807.1 - 6.7e-22 76.7 0.0 1.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EON99807.1 - 7.7e-13 48.5 0.1 2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 PDH PF02153.12 EON99807.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Pex14_N PF04695.8 EON99808.1 - 1.4e-35 122.2 0.0 1.4e-35 122.2 0.0 3.7 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 EON99808.1 - 0.0046 14.3 5.4 0.006 14.0 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 EON99808.1 - 0.0055 16.7 0.9 0.0055 16.7 0.6 1.8 2 0 0 2 2 2 1 Zinc finger-containing protein HLH PF00010.21 EON99808.1 - 0.01 15.5 4.5 1.1 9.0 0.1 3.2 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain Cytochrom_B562 PF07361.6 EON99808.1 - 0.044 14.1 4.0 0.1 13.0 2.8 1.7 1 0 0 1 1 1 0 Cytochrome b562 Mnd1 PF03962.10 EON99808.1 - 0.09 12.4 2.9 0.18 11.4 2.0 1.5 1 0 0 1 1 1 0 Mnd1 family Baculo_p24 PF05073.7 EON99808.1 - 0.1 12.1 1.0 0.22 11.0 0.1 1.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF1978 PF09321.5 EON99808.1 - 0.13 11.6 5.6 0.21 11.0 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) IncA PF04156.9 EON99808.1 - 0.18 11.3 3.8 0.056 13.0 0.5 1.7 2 0 0 2 2 2 0 IncA protein Myosin_tail_1 PF01576.14 EON99808.1 - 0.19 9.4 13.7 0.26 8.9 9.5 1.1 1 0 0 1 1 1 0 Myosin tail CENP-Q PF13094.1 EON99808.1 - 0.22 11.5 10.7 0.4 10.6 7.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 EON99808.1 - 0.23 11.2 5.9 0.81 9.5 0.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EON99808.1 - 0.28 8.6 2.0 0.39 8.1 1.4 1.2 1 0 0 1 1 1 0 Prominin PilJ PF13675.1 EON99808.1 - 0.39 11.0 7.1 0.48 10.7 3.0 2.5 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF848 PF05852.6 EON99808.1 - 0.7 9.7 8.0 1.5 8.7 5.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin PF00804.20 EON99808.1 - 0.73 10.0 6.9 24 5.1 4.8 2.4 1 1 0 1 1 1 0 Syntaxin Bacillus_HBL PF05791.6 EON99808.1 - 1.5 8.1 5.6 0.43 9.9 0.8 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.17 EON99808.1 - 1.9 8.5 9.1 2.5 8.1 1.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sipho_Gp157 PF05565.6 EON99808.1 - 2.4 7.7 7.3 11 5.5 1.4 2.2 1 1 0 2 2 2 0 Siphovirus Gp157 AAA_13 PF13166.1 EON99808.1 - 2.8 6.2 6.1 5.7 5.2 4.2 1.4 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 EON99808.1 - 3.1 6.6 8.3 4.8 6.0 5.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 EON99808.1 - 8.7 6.6 12.0 8.8 6.6 2.6 2.8 2 1 1 3 3 3 0 Spectrin repeat HR1 PF02185.11 EON99808.1 - 9.1 6.1 8.6 21 4.9 1.3 2.5 1 1 1 2 2 2 0 Hr1 repeat WD40 PF00400.27 EON99809.1 - 2.1e-05 24.1 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EON99809.1 - 0.0011 17.8 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PQQ PF01011.16 EON99809.1 - 0.014 14.9 1.0 0.037 13.5 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat eIF2A PF08662.6 EON99809.1 - 0.023 14.4 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A dCMP_cyt_deam_1 PF00383.17 EON99810.1 - 2.4e-14 52.8 0.0 3.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EON99810.1 - 0.0032 17.1 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EON99810.1 - 0.073 12.7 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Pkinase PF00069.20 EON99811.1 - 2.4e-10 40.0 0.0 3.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EON99811.1 - 4.2e-06 26.6 0.3 0.00015 21.5 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EON99811.1 - 0.0024 16.9 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EON99811.1 - 0.0057 15.9 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EON99811.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.12 EON99811.1 - 0.044 12.8 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_4 PF02390.12 EON99812.1 - 1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EON99812.1 - 1.3e-05 25.6 0.0 2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EON99812.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EON99812.1 - 0.00026 20.0 0.0 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_12 PF08242.7 EON99812.1 - 0.0012 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON99812.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EON99812.1 - 0.004 17.6 0.0 0.031 14.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99812.1 - 0.0057 16.2 0.1 0.012 15.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99812.1 - 0.012 15.9 0.1 0.043 14.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EON99812.1 - 0.046 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EON99812.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EON99812.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WWbp PF10349.4 EON99813.1 - 2e-09 38.3 1.2 3.6e-09 37.5 0.9 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EON99813.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 MRP-L27 PF09809.4 EON99814.1 - 1.2e-14 53.8 0.2 1.8e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF1939 PF09154.5 EON99814.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Pkinase PF00069.20 EON99815.1 - 1.7e-58 197.8 0.0 2.2e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99815.1 - 3.7e-30 104.8 0.0 4.9e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EON99815.1 - 0.0003 19.8 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON99815.1 - 0.01 15.5 0.2 0.01 15.5 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EON99815.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 EON99816.1 - 1.1e-32 113.9 0.0 2.1e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_4 PF01565.18 EON99817.1 - 3.1e-19 68.8 0.1 4.8e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON99817.1 - 3e-07 30.2 0.1 1e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.9 EON99817.1 - 0.0041 16.7 0.0 0.075 12.6 0.0 2.3 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase UCH PF00443.24 EON99818.1 - 2e-32 112.4 0.0 5.5e-32 110.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EON99818.1 - 5e-17 62.2 0.0 5.6e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IFRD PF05004.8 EON99818.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Homoserine_dh PF00742.14 EON99819.1 - 9.7e-52 175.2 0.0 1.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EON99819.1 - 3.2e-16 59.7 0.0 5.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Zip PF02535.17 EON99820.1 - 1e-27 97.0 4.0 1.2e-27 96.7 2.8 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter DCD PF06559.6 EON99820.1 - 0.12 10.7 0.0 0.23 9.7 0.0 1.4 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) AAA PF00004.24 EON99821.1 - 1.8e-21 76.7 0.0 5.9e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EON99821.1 - 9.2e-05 22.4 0.7 0.0013 18.8 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EON99821.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EON99821.1 - 0.00032 20.6 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EON99821.1 - 0.00071 19.7 0.2 0.014 15.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EON99821.1 - 0.0063 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EON99821.1 - 0.0089 16.3 0.0 0.0089 16.3 0.0 3.4 4 2 0 4 4 3 1 AAA domain AAA_14 PF13173.1 EON99821.1 - 0.0093 15.8 0.0 0.033 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EON99821.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EON99821.1 - 0.013 16.3 0.0 0.013 16.3 0.0 3.5 3 2 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EON99821.1 - 0.028 13.4 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EON99821.1 - 0.03 13.7 0.1 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.1 EON99821.1 - 0.032 13.7 1.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 EON99821.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin ResIII PF04851.10 EON99821.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNA_polI_A14 PF08203.6 EON99821.1 - 0.56 10.4 2.8 11 6.3 0.0 3.7 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 VHS PF00790.14 EON99822.1 - 1.9e-41 140.9 2.0 1.3e-40 138.3 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EON99822.1 - 1.5e-15 56.8 4.2 2.5e-15 56.1 2.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EON99822.1 - 3.7e-05 22.9 15.0 0.0048 16.3 0.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EON99822.1 - 0.00057 19.3 1.3 0.0011 18.4 0.9 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ribosomal_S30AE PF02482.14 EON99822.1 - 0.0083 16.5 0.6 0.035 14.5 0.1 2.3 2 0 0 2 2 2 1 Sigma 54 modulation protein / S30EA ribosomal protein FYVE_2 PF02318.11 EON99822.1 - 0.012 15.5 1.3 0.029 14.2 0.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Nop14 PF04147.7 EON99823.1 - 0.001 17.1 9.8 0.0016 16.4 6.8 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EON99823.1 - 0.0059 15.9 2.9 0.0078 15.5 2.0 1.2 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.6 EON99823.1 - 0.013 14.8 1.9 0.023 14.0 1.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EON99823.1 - 0.031 12.3 1.5 0.035 12.1 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ERM PF00769.14 EON99823.1 - 0.088 12.3 0.6 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FAM176 PF14851.1 EON99823.1 - 0.15 11.7 0.5 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EON99823.1 - 0.67 9.5 6.2 1.2 8.6 4.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EON99823.1 - 2.1 8.1 6.7 3.1 7.5 4.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 EON99823.1 - 6.3 5.7 5.7 8.8 5.2 4.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2014 PF09427.5 EON99824.1 - 1.4e-106 355.4 6.5 2e-106 354.9 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EON99824.1 - 2.3e-17 62.4 0.8 5.7e-17 61.1 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sigma70_ner PF04546.8 EON99824.1 - 0.019 14.5 2.5 0.04 13.5 1.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Reticulon PF02453.12 EON99824.1 - 0.075 12.6 0.3 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Reticulon PBP1_TM PF14812.1 EON99824.1 - 0.13 12.5 5.4 0.39 11.0 3.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EON99824.1 - 1.1 8.7 6.2 3.5 7.1 3.2 2.2 2 0 0 2 2 2 0 Nucleoplasmin Glyoxalase PF00903.20 EON99825.1 - 2.7e-41 140.5 0.2 1.8e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EON99825.1 - 8.3e-33 113.2 0.1 5.2e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EON99825.1 - 6.4e-18 64.7 0.1 3e-07 30.4 0.0 3.8 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EON99825.1 - 2.4e-07 30.8 0.0 0.12 12.2 0.0 3.4 3 1 0 3 3 3 2 Glyoxalase-like domain CppA_N PF14506.1 EON99825.1 - 0.024 14.2 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 CppA N-terminal Pkinase PF00069.20 EON99826.1 - 5.9e-08 32.1 0.0 9.4e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Drf_GBD PF06371.8 EON99827.1 - 5.4e-14 51.9 2.0 1.6e-12 47.1 1.4 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain MAPEG PF01124.13 EON99828.1 - 2.4e-22 78.9 0.5 2.8e-22 78.7 0.4 1.0 1 0 0 1 1 1 1 MAPEG family p450 PF00067.17 EON99830.1 - 1.5e-27 96.2 0.0 1.9e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SPC12 PF06645.8 EON99830.1 - 0.13 12.0 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cation_efflux PF01545.16 EON99831.1 - 3e-22 79.0 4.9 4.1e-22 78.5 3.4 1.1 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_43 PF04616.9 EON99832.1 - 4.8e-05 22.5 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 2-Hacid_dh_C PF02826.14 EON99834.1 - 1e-51 174.6 0.0 1.5e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EON99834.1 - 1e-34 118.8 0.5 2.9e-34 117.4 0.1 1.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 EON99834.1 - 0.024 14.1 0.8 0.061 12.8 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ACT PF01842.20 EON99834.1 - 0.072 12.5 0.0 0.072 12.5 0.0 3.1 3 1 1 4 4 4 0 ACT domain DnaJ PF00226.26 EON99835.1 - 3e-24 84.5 1.1 1.2e-23 82.6 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain SIMPL PF04402.9 EON99835.1 - 0.0077 16.1 1.1 0.0077 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF541) RPT PF13446.1 EON99835.1 - 0.032 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein PNPase PF03726.9 EON99835.1 - 4.5 7.6 13.5 8 6.8 0.8 3.9 4 1 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain MFS_1 PF07690.11 EON99836.1 - 2.4e-34 118.5 27.5 5e-34 117.5 19.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 EON99836.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.4 3 1 1 5 5 5 0 NfeD-like C-terminal, partner-binding WGG PF10273.4 EON99837.1 - 4.1e-34 116.5 0.0 7e-34 115.7 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TFIIF_alpha PF05793.7 EON99837.1 - 0.011 14.1 5.9 0.012 14.0 4.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2151 PF10221.4 EON99837.1 - 0.054 11.6 1.0 0.068 11.3 0.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4619 PF15398.1 EON99837.1 - 0.066 12.6 0.1 0.08 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) SDA1 PF05285.7 EON99837.1 - 0.29 10.3 8.6 0.44 9.7 5.9 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 EON99837.1 - 0.29 10.9 1.7 0.44 10.3 1.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EON99837.1 - 1.4 8.1 4.7 1.8 7.7 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.6 EON99837.1 - 2.7 7.0 9.9 0.66 9.0 3.8 1.8 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF1604 PF07713.8 EON99838.1 - 1.8e-38 130.1 3.0 1.8e-38 130.1 2.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EON99838.1 - 2.3e-07 30.4 2.1 2.3e-06 27.2 0.8 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EON99838.1 - 0.00023 20.9 0.7 0.0081 15.9 0.1 3.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site GST_C PF00043.20 EON99839.1 - 1.1e-09 38.0 0.3 3.6e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EON99839.1 - 2.4e-07 30.5 0.8 5.6e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EON99839.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EON99839.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EON99839.1 - 5.9e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EON99839.1 - 0.00097 19.5 0.9 0.0026 18.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF21 PF01595.15 EON99840.1 - 7.8e-34 116.5 0.0 1.2e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EON99840.1 - 2.7e-08 33.4 0.3 0.0034 17.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain Glyco_hydro_47 PF01532.15 EON99841.1 - 1.8e-115 386.2 0.0 2e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 EON99841.1 - 0.12 12.7 0.1 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Piwi PF02171.12 EON99842.1 - 6.4e-64 215.8 0.0 9.8e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EON99842.1 - 1.8e-11 43.4 0.0 3.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EON99842.1 - 7.8e-09 34.7 0.0 5.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Sugar_tr PF00083.19 EON99843.1 - 1.2e-29 103.2 1.4 1.6e-29 102.8 1.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Lipase_GDSL PF00657.17 EON99844.1 - 1.3e-10 41.5 0.3 2.2e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Acyltransferase PF01553.16 EON99845.1 - 1.6e-10 40.4 0.0 6.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Methyltransf_23 PF13489.1 EON99846.1 - 1.2e-20 73.8 0.1 1.5e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EON99846.1 - 9.5e-11 41.5 0.0 1.6e-09 37.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EON99846.1 - 2.2e-09 37.9 0.1 4.7e-08 33.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EON99846.1 - 2.2e-09 37.6 0.0 1.1e-08 35.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EON99846.1 - 1.9e-08 34.7 0.0 6e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EON99846.1 - 2.3e-06 27.8 0.0 6.3e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EON99846.1 - 8.8e-05 21.7 0.0 0.00076 18.6 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EON99846.1 - 0.0012 18.9 0.0 0.0033 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EON99846.1 - 0.0013 18.1 0.0 0.0057 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EON99846.1 - 0.0027 16.8 0.0 0.0052 15.9 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EON99846.1 - 0.0037 16.3 0.0 0.0084 15.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EON99846.1 - 0.0063 15.9 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EON99846.1 - 0.037 13.2 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase NDT80_PhoG PF05224.7 EON99847.1 - 2e-35 122.5 0.0 2.7e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pectinesterase PF01095.14 EON99848.1 - 3.1e-53 180.3 7.4 4.1e-53 179.8 5.2 1.1 1 0 0 1 1 1 1 Pectinesterase NTNH_C PF08470.5 EON99848.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Peroxidase_2 PF01328.12 EON99849.1 - 0.0088 14.7 0.2 0.015 13.9 0.2 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 CcmD PF04995.9 EON99849.1 - 0.15 11.7 0.3 0.36 10.5 0.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rcd1 PF04078.8 EON99850.1 - 1.8e-131 436.7 4.7 2.1e-131 436.5 3.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF2930 PF11152.3 EON99850.1 - 0.037 13.1 0.6 0.067 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) CTP_transf_2 PF01467.21 EON99851.1 - 7.5e-27 94.3 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase COX15-CtaA PF02628.10 EON99852.1 - 8.8e-96 320.3 9.8 1.1e-95 319.9 6.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF754 PF05449.6 EON99852.1 - 0.13 12.3 0.1 0.13 12.3 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF754) Na_H_Exchanger PF00999.16 EON99853.1 - 2.2e-68 230.5 44.5 3.1e-68 230.0 30.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease_2 PF13520.1 EON99854.1 - 0.036 12.6 11.8 0.089 11.3 0.1 2.9 3 0 0 3 3 3 0 Amino acid permease Pkinase PF00069.20 EON99855.1 - 2.6e-76 256.1 0.0 4.1e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EON99855.1 - 1.4e-39 135.7 0.0 3.1e-39 134.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EON99855.1 - 4e-17 61.3 0.1 6.8e-17 60.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EON99855.1 - 6.9e-06 25.2 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EON99855.1 - 9.1e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EON99855.1 - 0.0048 16.6 0.0 0.028 14.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EON99855.1 - 0.029 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EON99855.1 - 0.038 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 EON99855.1 - 0.16 11.1 0.1 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ABC_tran PF00005.22 EON99856.1 - 5.2e-48 162.8 0.3 1.3e-25 90.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EON99856.1 - 9.5e-25 87.3 37.6 5.9e-17 61.7 16.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EON99856.1 - 4.7e-22 79.2 0.8 7.6e-09 35.9 0.1 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EON99856.1 - 1.9e-09 36.8 6.7 6e-05 22.4 0.5 3.3 4 0 0 4 4 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EON99856.1 - 3.3e-09 36.3 1.6 0.025 13.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EON99856.1 - 1.6e-05 24.9 1.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EON99856.1 - 1.7e-05 25.2 6.6 0.031 14.6 0.4 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EON99856.1 - 0.00017 20.8 1.6 0.17 11.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EON99856.1 - 0.0026 17.2 0.3 1.4 8.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EON99856.1 - 0.0032 16.5 0.0 0.64 8.9 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EON99856.1 - 0.016 14.8 1.3 3.2 7.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EON99856.1 - 0.017 15.2 0.7 2.4 8.3 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EON99856.1 - 0.022 14.6 0.2 11 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EON99856.1 - 0.063 12.7 2.3 1.9 7.8 0.3 2.4 2 0 0 2 2 2 0 AAA-like domain MutS_V PF00488.16 EON99856.1 - 0.085 12.2 0.1 6.6 6.0 0.0 2.5 2 0 0 2 2 2 0 MutS domain V SRP54 PF00448.17 EON99856.1 - 0.086 12.2 1.4 11 5.4 0.2 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EON99856.1 - 0.1 12.5 1.3 4 7.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EON99856.1 - 0.11 11.6 1.5 4.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EON99856.1 - 0.22 11.4 0.6 19 5.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EON99856.1 - 0.25 9.7 0.2 2.9 6.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EON99856.1 - 0.91 8.1 0.1 4.3 5.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Bac_luciferase PF00296.15 EON99857.1 - 3.3e-48 164.3 2.4 4.5e-48 163.9 1.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FumaraseC_C PF10415.4 EON99857.1 - 0.07 13.1 0.2 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus HMG_CoA_synt_C PF08540.5 EON99858.1 - 3.2e-97 325.3 0.0 4.6e-97 324.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EON99858.1 - 1.6e-92 307.8 0.2 2.2e-92 307.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Pyr_redox PF00070.22 EON99859.1 - 8.3e-16 58.1 0.3 4e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EON99859.1 - 9.1e-13 48.5 0.0 2e-11 44.1 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EON99859.1 - 2.1e-07 31.2 0.0 1.5e-05 25.1 0.0 2.5 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EON99859.1 - 4.2e-07 29.2 0.0 0.00079 18.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EON99859.1 - 7.6e-05 21.7 0.0 0.43 9.4 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EON99859.1 - 0.00018 21.3 1.9 1.3 8.7 0.0 4.1 4 1 0 5 5 5 2 FAD-NAD(P)-binding DAO PF01266.19 EON99859.1 - 0.0007 18.6 0.2 1.1 8.1 0.0 2.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON99859.1 - 0.00072 19.5 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EON99859.1 - 0.0032 17.4 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 EON99859.1 - 0.016 13.6 0.0 5.5 5.3 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EON99859.1 - 0.052 13.2 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EON99859.1 - 0.072 11.9 0.1 13 4.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 EON99859.1 - 0.086 11.9 0.2 0.82 8.7 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.9 EON99859.1 - 0.098 11.2 0.0 2.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.16 EON99859.1 - 0.33 10.7 1.4 2.2 8.1 0.3 2.7 2 1 1 3 3 3 0 ThiF family Zn_clus PF00172.13 EON99860.1 - 0.0021 17.9 7.7 0.005 16.7 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EON99861.1 - 4.9e-28 98.5 0.2 9.8e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON99861.1 - 3.1e-06 27.0 0.0 2.7e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EON99861.1 - 0.00017 21.2 0.0 0.00036 20.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EON99861.1 - 0.00039 19.7 0.0 0.0011 18.2 0.0 1.8 2 1 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EON99861.1 - 0.1 11.4 0.0 0.24 10.2 0.0 1.6 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.9 EON99861.1 - 0.17 10.3 0.0 0.51 8.7 0.0 1.7 2 0 0 2 2 2 0 Ndr family MFS_1 PF07690.11 EON99862.1 - 1.7e-23 82.9 37.9 1.7e-23 82.9 26.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2417 PF10329.4 EON99862.1 - 0.0098 15.3 1.7 0.02 14.3 1.2 1.5 1 0 0 1 1 1 1 Region of unknown function (DUF2417) MFS_1_like PF12832.2 EON99862.1 - 0.052 13.3 0.2 0.052 13.3 0.1 2.4 3 0 0 3 3 3 0 MFS_1 like family Na_Ca_ex PF01699.19 EON99863.1 - 2.2e-46 156.9 32.1 7.9e-24 83.8 4.3 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.15 EON99863.1 - 0.13 12.4 0.1 5.8 7.1 0.0 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4131 PF13567.1 EON99863.1 - 5.3 6.4 6.1 4.7 6.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Complex1_30kDa PF00329.14 EON99864.1 - 1.3e-35 121.6 0.0 2e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BNR PF02012.15 EON99866.1 - 9.2e-07 27.7 40.4 0.14 12.1 0.2 9.5 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_2 PF13088.1 EON99866.1 - 0.0027 17.0 14.4 6.7 5.9 0.7 4.5 2 2 1 4 4 4 4 BNR repeat-like domain AA_permease PF00324.16 EON99867.1 - 5.6e-28 97.5 30.0 7.1e-28 97.1 20.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EON99867.1 - 4.6e-18 64.9 32.3 6e-18 64.6 22.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pyridox_ox_2 PF12900.2 EON99868.1 - 4.8e-31 107.5 0.0 6.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Abhydrolase_5 PF12695.2 EON99871.1 - 9.8e-10 38.3 0.0 4.9e-09 36.0 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EON99871.1 - 4.8e-08 33.1 0.7 1.2e-07 31.9 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EON99871.1 - 4.9e-07 29.1 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EON99871.1 - 0.0064 15.7 0.0 0.071 12.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EON99871.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 EON99871.1 - 0.044 12.0 0.0 0.11 10.7 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1100 PF06500.6 EON99871.1 - 0.066 11.7 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_2 PF02230.11 EON99871.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EON99871.1 - 0.12 11.7 0.0 0.78 9.1 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Oxidored_FMN PF00724.15 EON99872.1 - 9.8e-64 215.4 0.0 1.2e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AAA PF00004.24 EON99873.1 - 1.7e-12 47.6 0.0 8.1e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EON99873.1 - 1.9e-05 24.7 0.1 6.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EON99873.1 - 0.00014 20.9 0.0 0.00039 19.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EON99873.1 - 0.00027 21.0 0.0 0.001 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EON99873.1 - 0.00035 20.4 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EON99873.1 - 0.0014 19.3 0.0 0.005 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EON99873.1 - 0.002 18.0 0.0 0.027 14.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EON99873.1 - 0.0025 18.1 0.0 0.009 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EON99873.1 - 0.0038 17.1 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EON99873.1 - 0.0067 16.0 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EON99873.1 - 0.012 14.8 0.0 0.47 9.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CbiA PF01656.18 EON99873.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EON99873.1 - 0.022 13.5 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF4391 PF14335.1 EON99873.1 - 0.025 13.9 4.2 2.6 7.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) AAA_5 PF07728.9 EON99873.1 - 0.027 14.2 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EON99873.1 - 0.035 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EON99873.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 EON99873.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EON99873.1 - 0.084 12.5 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EON99873.1 - 0.17 11.0 0.3 1.3 8.1 0.1 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MARVEL PF01284.18 EON99874.1 - 9.7e-23 80.5 1.2 1.2e-22 80.2 0.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2207 PF09972.4 EON99874.1 - 1 7.8 6.2 1.2 7.6 0.0 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3632 PF12311.3 EON99875.1 - 1.4e-15 57.5 1.5 2.1e-15 57.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3653 PF12375.3 EON99875.1 - 0.018 15.2 3.7 0.027 14.6 1.1 2.2 2 0 0 2 2 2 0 Phage protein Transp_cyt_pur PF02133.10 EON99876.1 - 2.2e-22 79.2 40.5 4.3e-22 78.2 28.1 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IlvN PF07991.7 EON99877.1 - 4.6e-46 156.2 0.0 6.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EON99877.1 - 4.4e-44 149.9 0.0 6.5e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EON99877.1 - 0.011 16.1 0.0 0.037 14.4 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EON99878.1 - 3.8e-23 81.4 0.1 7.7e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EON99878.1 - 4e-20 73.0 0.1 1.6e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EON99878.1 - 2.3e-10 40.2 0.0 3e-09 36.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-U1 PF06220.7 EON99879.1 - 5.8e-22 76.9 3.4 8.5e-22 76.4 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EON99879.1 - 0.02 15.0 3.4 0.042 14.0 2.4 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Fasciclin PF02469.17 EON99880.1 - 3.7e-24 85.1 0.1 7.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Viral_protease PF08715.5 EON99880.1 - 0.017 14.2 0.0 0.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Papain like viral protease Amidohydro_2 PF04909.9 EON99881.1 - 1.3e-25 90.5 0.1 1.7e-25 90.1 0.1 1.2 1 1 0 1 1 1 1 Amidohydrolase HD PF01966.17 EON99882.1 - 3.4e-05 23.8 0.3 0.00011 22.1 0.1 2.0 2 0 0 2 2 2 1 HD domain Kinetocho_Slk19 PF12709.2 EON99883.1 - 3e-19 68.8 2.4 3e-19 68.8 1.6 4.3 3 1 0 4 4 4 2 Central kinetochore-associated DUF2605 PF10792.4 EON99883.1 - 0.014 15.0 1.3 0.044 13.4 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) FlaC_arch PF05377.6 EON99883.1 - 1.3 8.9 15.1 0.29 11.0 0.8 4.4 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) PCI PF01399.22 EON99884.1 - 0.0078 16.5 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EON99884.1 - 0.085 12.8 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TRP PF06011.7 EON99885.1 - 2.3e-150 501.0 32.9 2.9e-150 500.6 22.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EON99885.1 - 4.8e-41 140.1 0.3 7.7e-41 139.4 0.2 1.3 1 0 0 1 1 1 1 ML-like domain DUF3433 PF11915.3 EON99886.1 - 8e-44 147.7 8.6 2e-25 88.7 0.7 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pho86 PF11124.3 EON99886.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 GST_C_2 PF13410.1 EON99888.1 - 1.6e-06 27.9 0.2 2.6e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EON99888.1 - 1.2e-05 25.2 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EON99888.1 - 2.3e-05 24.7 0.0 3.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EON99888.1 - 0.022 14.9 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CBM_20 PF00686.14 EON99889.1 - 0.04 13.5 0.2 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 Starch binding domain Golgin_A5 PF09787.4 EON99889.1 - 1.2 7.5 7.2 1.7 7.0 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Zip PF02535.17 EON99889.1 - 3.3 6.6 4.5 4.3 6.2 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3827 PF12877.2 EON99889.1 - 5.6 4.9 9.0 8.3 4.3 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Apt1 PF10351.4 EON99889.1 - 6.8 5.4 11.3 0.38 9.5 4.2 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain AMP-binding PF00501.23 EON99890.1 - 5.7e-79 265.4 0.0 6.9e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EON99890.1 - 5.1e-14 52.9 0.2 5.5e-13 49.6 0.0 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain IncA PF04156.9 EON99891.1 - 0.054 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 IncA protein VSP PF03302.8 EON99891.1 - 0.059 11.9 0.8 0.095 11.3 0.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Ras PF00071.17 EON99892.1 - 1.3e-51 174.1 0.0 2.2e-51 173.4 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EON99892.1 - 2e-17 63.7 0.0 9.8e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EON99892.1 - 0.00025 20.3 0.0 0.00067 18.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EON99892.1 - 0.0093 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EON99892.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EON99892.1 - 0.021 14.0 0.1 0.27 10.5 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.5 EON99892.1 - 0.055 12.6 0.0 0.94 8.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Abhydrolase_4 PF08386.5 EON99892.1 - 0.067 13.0 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein AAA_25 PF13481.1 EON99892.1 - 0.08 12.3 0.2 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EON99892.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Septin DUF2075 PF09848.4 EON99892.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) C1q PF00386.16 EON99893.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 C1q domain SNF2_N PF00176.18 EON99894.1 - 4.9e-55 186.4 0.0 6.9e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EON99894.1 - 9e-13 47.9 0.0 2.8e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EON99894.1 - 1.5e-11 43.6 0.8 3.8e-11 42.3 0.6 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.1 EON99894.1 - 0.012 14.9 0.1 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 EON99894.1 - 0.014 15.0 7.8 0.4 10.4 3.7 3.4 2 1 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.8 EON99894.1 - 0.016 15.1 0.7 0.042 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) SnAC PF14619.1 EON99894.1 - 0.05 13.7 6.2 0.28 11.3 0.3 3.2 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex SUR7 PF06687.7 EON99895.1 - 6.7e-26 91.1 16.4 2.2e-23 82.9 7.9 1.4 1 1 1 2 2 2 2 SUR7/PalI family Fig1 PF12351.3 EON99895.1 - 0.07 13.0 10.1 0.085 12.7 7.0 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 MBF1 PF08523.5 EON99896.1 - 2.8e-26 91.3 2.5 2.8e-26 91.3 1.7 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EON99896.1 - 2.6e-11 43.2 0.0 4.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EON99896.1 - 0.00064 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EON99896.1 - 0.003 17.5 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 EON99896.1 - 0.017 14.7 0.1 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_24 PF13412.1 EON99896.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Pyr_redox_dim PF02852.17 EON99896.1 - 0.069 13.1 0.1 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF3813 PF12758.2 EON99896.1 - 0.12 12.4 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) KilA-N PF04383.8 EON99897.1 - 0.00015 21.3 0.0 0.0027 17.3 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain bZIP_1 PF00170.16 EON99898.1 - 5.2e-14 51.9 6.4 7.9e-14 51.3 4.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EON99898.1 - 1.4e-07 31.1 6.3 2.5e-07 30.4 4.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EON99898.1 - 0.00018 21.7 2.7 0.00033 20.8 1.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.8 EON99898.1 - 0.023 13.6 3.6 0.032 13.2 2.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HeLo PF14479.1 EON99898.1 - 0.078 12.7 1.6 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation DivIC PF04977.10 EON99898.1 - 0.11 11.9 1.0 0.18 11.2 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 EON99898.1 - 0.14 11.9 1.3 0.33 10.7 0.9 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tom37_C PF11801.3 EON99898.1 - 0.15 11.9 1.5 0.22 11.3 1.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Macoilin PF09726.4 EON99898.1 - 0.16 10.2 7.6 0.18 10.0 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein NpwBP PF12622.2 EON99898.1 - 0.68 10.4 3.5 1.1 9.8 0.2 2.4 2 0 0 2 2 2 0 mRNA biogenesis factor Chitin_synth_1 PF01644.12 EON99900.1 - 2.4e-70 235.5 0.0 3.4e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EON99900.1 - 3.5e-27 95.0 0.0 3e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EON99900.1 - 8.9e-27 92.6 0.1 1.6e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EON99900.1 - 2.2e-11 43.8 3.3 1.4e-10 41.1 2.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EON99900.1 - 8.5e-09 35.5 0.0 5.6e-08 32.8 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UPF0542 PF15086.1 EON99901.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 UQ_con PF00179.21 EON99902.1 - 6.8e-38 129.2 0.0 8.9e-38 128.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EON99902.1 - 0.066 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B OTU PF02338.14 EON99903.1 - 3.9e-20 72.6 0.1 2.1e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EON99903.1 - 0.013 14.8 0.0 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase C65 Otubain F-box-like PF12937.2 EON99904.1 - 6e-05 22.6 1.1 0.00011 21.8 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EON99904.1 - 0.00026 20.5 0.3 0.00065 19.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain GFA PF04828.9 EON99905.1 - 1.7e-21 75.9 0.0 2.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EON99905.1 - 0.043 13.0 0.2 0.42 9.8 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EON99905.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.9 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 EON99905.1 - 0.29 10.6 0.1 0.29 10.6 0.0 2.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EON99905.1 - 0.4 10.5 3.8 1 9.2 1.5 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 EON99905.1 - 1.2 8.7 0.1 1.2 8.7 0.0 2.7 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF3418 PF11898.3 EON99906.1 - 0.019 13.3 0.9 0.022 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) MFS_1 PF07690.11 EON99907.1 - 2.1e-31 108.9 17.9 2.1e-31 108.9 12.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EON99907.1 - 0.001 17.7 0.9 0.001 17.7 0.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Amidohydro_2 PF04909.9 EON99908.1 - 1.3e-07 31.5 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EON99908.1 - 1.6e-05 25.1 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sdh5 PF03937.11 EON99909.1 - 1.1e-23 82.6 0.1 2.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DLH PF01738.13 EON99910.1 - 4.8e-21 75.0 0.0 4.8e-20 71.7 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EON99910.1 - 3.1e-10 39.9 0.0 5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EON99910.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 EON99911.1 - 1.5e-24 86.7 1.2 2.1e-24 86.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EON99911.1 - 1.7e-14 54.1 0.0 4e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EON99911.1 - 3.4e-08 33.3 0.5 5.2e-08 32.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Flu_C_NS1 PF03506.8 EON99911.1 - 0.011 15.4 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 0 Influenza C non-structural protein (NS1) GDPD_2 PF13653.1 EON99911.1 - 0.053 13.7 0.2 8.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family AA_kinase PF00696.23 EON99911.1 - 0.11 12.0 0.3 0.53 9.7 0.2 1.9 1 1 1 2 2 2 0 Amino acid kinase family YqfQ PF14181.1 EON99911.1 - 0.13 12.2 0.5 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 YqfQ-like protein Aldedh PF00171.17 EON99912.1 - 4.9e-13 48.2 6.3 4.7e-08 31.8 3.4 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 EON99912.1 - 0.042 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Rep_fac-A_C PF08646.5 EON99913.1 - 2.8e-54 182.7 4.0 2.5e-52 176.4 1.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EON99913.1 - 4.9e-21 74.4 0.0 1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EON99913.1 - 9.2e-18 63.8 0.4 5e-11 42.3 0.0 4.3 4 1 0 4 4 4 3 OB-fold nucleic acid binding domain zf-like PF04071.7 EON99913.1 - 0.071 12.8 0.3 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain Fumerase_C PF05683.7 EON99913.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Fumarase C-terminus HAD_2 PF13419.1 EON99914.1 - 5.2e-24 85.4 0.0 1.2e-23 84.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EON99914.1 - 3.3e-08 34.2 0.0 6.4e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EON99914.1 - 3.9e-06 26.4 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Tfb2 PF03849.9 EON99914.1 - 0.049 12.2 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb2 EMP24_GP25L PF01105.19 EON99915.1 - 1.3e-41 142.3 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RE_SacI PF09566.5 EON99915.1 - 0.076 11.9 0.1 0.11 11.4 0.1 1.3 1 1 0 1 1 1 0 SacI restriction endonuclease DUF4337 PF14235.1 EON99915.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ADH_N PF08240.7 EON99916.1 - 1.3e-23 82.8 4.2 2.1e-23 82.1 2.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EON99916.1 - 4e-08 32.8 0.2 8e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EON99916.1 - 0.0015 17.6 0.1 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 EON99916.1 - 0.06 13.1 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) NMT1 PF09084.6 EON99917.1 - 1.6e-78 263.2 0.0 2.4e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EON99917.1 - 3.3e-09 36.5 0.2 0.038 13.3 0.1 3.6 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 EON99917.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 EON99917.1 - 0.12 11.2 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain MFS_1 PF07690.11 EON99918.1 - 7.4e-33 113.7 50.4 1.6e-27 96.2 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EON99918.1 - 5.8e-11 41.6 36.4 1e-05 24.3 9.9 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EON99918.1 - 0.00035 20.3 1.6 0.036 13.8 0.1 3.6 3 1 1 4 4 4 1 MFS_1 like family LRR_4 PF12799.2 EON99919.1 - 0.044 13.4 0.0 17 5.1 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Acyl_transf_3 PF01757.17 EON99920.1 - 6e-15 54.9 23.0 7.5e-15 54.5 15.9 1.1 1 0 0 1 1 1 1 Acyltransferase family CP_ATPgrasp_2 PF14403.1 EON99921.1 - 0.027 13.1 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Abhydrolase_6 PF12697.2 EON99923.1 - 3e-13 50.2 0.2 5.6e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EON99923.1 - 8.9e-11 41.7 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EON99923.1 - 7.4e-07 28.6 0.0 1e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.6 EON99923.1 - 6.7e-06 24.9 0.0 9.4e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 EON99923.1 - 8.8e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EON99923.1 - 0.00016 20.3 0.1 0.0033 15.9 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EON99923.1 - 0.00019 20.7 0.0 0.0004 19.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EON99923.1 - 0.00028 20.4 0.1 0.00048 19.6 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EON99923.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EON99923.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DHDPS PF00701.17 EON99924.1 - 1.1e-46 158.8 0.0 1.3e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EON99924.1 - 0.0019 17.4 0.1 0.0032 16.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Amidohydro_2 PF04909.9 EON99924.1 - 0.11 12.1 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ABC2_membrane PF01061.19 EON99925.1 - 1.2e-82 276.1 63.4 5e-45 153.2 19.7 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EON99925.1 - 1.7e-37 127.1 7.7 2.7e-31 107.2 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EON99925.1 - 3.1e-18 66.3 0.0 5.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EON99925.1 - 5.2e-07 29.0 19.4 5.2e-07 29.0 13.4 3.6 3 2 1 4 4 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EON99925.1 - 0.0001 21.7 0.0 0.00023 20.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EON99925.1 - 0.00024 21.1 0.1 0.0008 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EON99925.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EON99925.1 - 0.0014 18.1 0.3 0.0023 17.4 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EON99925.1 - 0.0026 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EON99925.1 - 0.0076 15.7 0.2 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EON99925.1 - 0.011 14.9 0.0 0.081 12.1 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EON99925.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EON99925.1 - 0.033 14.1 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EON99925.1 - 0.037 14.8 0.0 0.1 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EON99925.1 - 0.17 12.0 0.1 0.4 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EON99925.1 - 0.37 11.0 0.4 1.3 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 EON99925.1 - 0.43 9.4 33.9 0.11 11.3 2.9 3.3 3 1 1 4 4 4 0 ABC-2 family transporter protein Amidase PF01425.16 EON99926.1 - 3.2e-44 151.5 1.9 2.6e-27 95.7 0.2 3.1 1 1 1 2 2 2 2 Amidase Amidohydro_2 PF04909.9 EON99926.1 - 1.3e-27 97.1 0.1 2.1e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EON99927.1 - 8e-28 97.1 44.9 5.7e-27 94.3 30.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EON99927.1 - 0.57 8.1 8.1 0.9 7.5 0.5 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4538 PF15061.1 EON99927.1 - 5.8 6.3 12.3 5.8 6.3 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4538) PIP5K PF01504.13 EON99928.1 - 4.7e-19 68.4 0.0 5.4e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF43 PF01861.11 EON99929.1 - 0.073 12.0 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF43 Polysacc_synt_3 PF13440.1 EON99929.1 - 0.5 9.7 7.4 1 8.7 0.6 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pam17 PF08566.5 EON99930.1 - 7.4e-66 221.1 0.1 9.5e-66 220.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 EON99930.1 - 0.013 14.5 0.3 0.018 14.0 0.2 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component VPEP PF07589.6 EON99930.1 - 5.2 7.1 5.5 21 5.1 3.8 2.1 1 0 0 1 1 1 0 PEP-CTERM motif LIP PF03583.9 EON99931.1 - 5e-66 222.8 0.4 6.4e-66 222.4 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase YaeQ PF07152.7 EON99932.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 YaeQ protein BTB PF00651.26 EON99933.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Metal_CEHH PF14455.1 EON99933.1 - 0.11 11.9 0.1 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted metal binding domain FAD_binding_3 PF01494.14 EON99934.1 - 1.8e-22 79.8 0.1 2.4e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EON99934.1 - 7.1e-07 28.4 0.1 0.00017 20.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EON99934.1 - 0.0012 18.8 0.1 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EON99934.1 - 0.0032 16.3 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase AlaDh_PNT_C PF01262.16 EON99934.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EON99934.1 - 0.0035 16.0 0.7 1.5 7.3 0.1 3.0 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EON99934.1 - 0.0046 15.8 0.0 0.0077 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EON99934.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EON99934.1 - 0.013 15.8 0.1 0.044 14.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhaP_Bmeg PF09602.5 EON99934.1 - 0.023 14.5 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Pyr_redox_2 PF07992.9 EON99934.1 - 0.029 14.2 0.0 0.073 12.9 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON99934.1 - 0.032 13.1 0.6 0.097 11.5 0.4 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Gly_transf_sug PF04488.10 EON99936.1 - 5.1e-13 49.3 0.1 1.1e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EON99936.1 - 0.38 9.1 2.7 1.4 7.3 0.2 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Pectate_lyase_3 PF12708.2 EON99937.1 - 2.8e-61 207.4 19.5 9.7e-55 186.1 11.2 3.1 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EON99937.1 - 0.13 11.7 1.1 0.41 10.1 0.2 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase FGGY_C PF02782.11 EON99938.1 - 0.036 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Epimerase PF01370.16 EON99939.1 - 3.6e-22 78.9 0.0 4.6e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EON99939.1 - 4.2e-10 38.8 0.0 5.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EON99939.1 - 1.6e-06 27.2 0.0 2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EON99939.1 - 2.2e-06 26.7 0.5 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EON99939.1 - 2.5e-05 24.3 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EON99939.1 - 0.00026 20.9 0.1 0.00091 19.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EON99939.1 - 0.0079 15.8 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EON99939.1 - 0.043 12.7 0.0 0.21 10.4 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Desmo_N PF06771.6 EON99941.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus PTCRA PF15028.1 EON99942.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Peptidase_C48 PF02902.14 EON99943.1 - 7.4e-19 68.2 0.0 2.2e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S9 PF00326.16 EON99944.1 - 8.2e-45 152.6 0.0 1.2e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EON99944.1 - 3.7e-06 25.7 0.0 5.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_5 PF12695.2 EON99944.1 - 0.00054 19.7 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EON99944.1 - 0.0068 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EON99944.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EON99944.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 EON99944.1 - 0.02 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 EON99944.1 - 0.055 13.0 0.0 0.22 11.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.2 EON99945.1 - 1.9e-24 85.7 0.5 2e-11 44.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EON99945.1 - 4.2e-13 48.3 6.0 1.3e-06 27.8 0.1 5.5 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EON99945.1 - 1.2e-11 43.6 1.3 4.5e-06 26.3 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EON99945.1 - 8.2e-10 38.6 2.4 1.6e-05 24.9 0.1 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EON99945.1 - 1.5e-08 34.8 1.1 0.013 16.0 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Glyco_hydro_2_N PF02837.13 EON99947.1 - 5.7e-21 74.7 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EON99947.1 - 2.7e-13 49.4 0.0 4.3e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EON99947.1 - 1.9e-11 44.3 0.3 5.2e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 MFS_1 PF07690.11 EON99948.1 - 1.9e-41 141.9 49.4 8.9e-41 139.7 34.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EON99948.1 - 3.3e-13 48.7 18.5 4.3e-13 48.3 12.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SLX9 PF15341.1 EON99949.1 - 1.2e-36 125.7 4.0 1.8e-36 125.2 2.8 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ThiF PF00899.16 EON99950.1 - 2.6e-23 82.3 0.3 4.3e-23 81.6 0.2 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EON99950.1 - 0.00058 19.9 0.2 0.001 19.1 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MscS_porin PF12795.2 EON99950.1 - 0.012 14.9 0.4 0.015 14.5 0.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.14 EON99950.1 - 0.017 12.8 0.2 0.021 12.5 0.1 1.1 1 0 0 1 1 1 0 Myosin tail Ldh_1_N PF00056.18 EON99950.1 - 0.022 14.5 0.3 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EON99950.1 - 0.029 13.4 1.6 0.041 12.9 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain HR1 PF02185.11 EON99950.1 - 0.03 14.0 0.8 0.048 13.3 0.3 1.5 2 0 0 2 2 2 0 Hr1 repeat ApbA PF02558.11 EON99950.1 - 0.081 12.3 0.9 0.12 11.7 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EON99950.1 - 0.087 13.2 0.9 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EON99950.1 - 0.2 10.5 1.4 0.28 9.9 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 EON99950.1 - 1.3 7.8 5.8 0.29 10.0 1.8 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 EON99951.1 - 7.5e-19 67.5 0.1 1.5e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EON99951.1 - 2.5e-10 40.0 0.2 2.5e-10 40.0 0.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.9 EON99951.1 - 0.001 18.7 0.1 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 EON99951.1 - 0.078 12.1 0.5 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_28 PF00295.12 EON99952.1 - 1.8e-98 329.5 17.9 2.2e-98 329.2 12.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EON99952.1 - 1.5e-05 24.8 41.9 0.038 13.7 28.9 3.7 1 1 0 1 1 1 1 Right handed beta helix region DUF4558 PF15104.1 EON99953.1 - 0.00084 19.2 2.6 0.0017 18.2 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) CENP-Q PF13094.1 EON99953.1 - 0.043 13.8 10.4 0.095 12.7 7.2 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 EON99953.1 - 0.25 10.3 11.8 0.38 9.7 8.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ALMT PF11744.3 EON99953.1 - 0.55 8.8 6.4 0.88 8.1 4.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.1 EON99953.1 - 1.9 7.3 8.8 3.3 6.5 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BATS PF06968.8 EON99954.1 - 4.4e-30 103.3 0.1 1.4e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EON99954.1 - 1.8e-17 63.9 0.4 4.5e-16 59.4 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Pectinesterase PF01095.14 EON99957.1 - 1.9e-41 141.5 7.8 2.5e-41 141.1 5.4 1.1 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.19 EOO00001.1 - 7.1e-60 202.8 15.0 8.7e-60 202.5 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.23 EOO00002.1 - 1.4e-81 274.0 0.0 1.7e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_S8 PF00082.17 EOO00002.1 - 0.0053 15.9 0.1 0.0093 15.1 0.1 1.3 1 0 0 1 1 1 1 Subtilase family GTPase_binding PF09027.5 EOO00002.1 - 0.062 12.8 0.0 6.1 6.5 0.0 2.6 2 0 0 2 2 2 0 GTPase binding BCA_ABC_TP_C PF12399.3 EOO00002.1 - 0.62 9.8 3.4 0.34 10.6 0.2 2.2 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Arm PF00514.18 EOO00003.1 - 1.8e-08 33.8 0.6 0.0076 16.0 0.0 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EOO00003.1 - 0.00022 21.0 4.9 2.6 8.3 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat DDE_Tnp_2 PF04693.7 EOO00003.1 - 0.022 13.8 0.0 0.054 12.5 0.0 1.5 2 0 0 2 2 2 0 Archaeal putative transposase ISC1217 Chromosome_seg PF13889.1 EOO00003.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation during meiosis zf-RING_2 PF13639.1 EOO00004.1 - 3.4e-08 33.1 9.6 3.4e-08 33.1 6.6 3.2 2 1 1 3 3 2 1 Ring finger domain zf-TRAF PF02176.13 EOO00004.1 - 8e-08 32.5 33.0 0.0017 18.6 2.7 4.6 2 1 2 4 4 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EOO00004.1 - 1e-07 31.8 10.5 1e-07 31.8 7.3 3.4 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO00004.1 - 3.3e-07 29.8 7.5 3.3e-07 29.8 5.2 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EOO00004.1 - 6.9e-06 25.6 8.5 6.9e-06 25.6 5.9 4.2 2 2 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO00004.1 - 1.8e-05 24.3 9.6 1.8e-05 24.3 6.7 3.6 3 2 1 4 4 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EOO00004.1 - 3.3e-05 23.4 4.0 3.3e-05 23.4 2.7 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-Nse PF11789.3 EOO00004.1 - 0.00021 20.7 6.9 0.00021 20.7 4.8 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EOO00004.1 - 0.00023 20.6 1.6 0.00023 20.6 1.1 4.2 5 0 0 5 5 4 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EOO00004.1 - 0.0012 18.9 4.3 0.0012 18.9 3.0 3.4 2 2 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EOO00004.1 - 0.0013 18.5 7.6 0.0013 18.5 5.2 3.5 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EOO00004.1 - 0.0019 17.6 4.5 0.0019 17.6 3.1 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 AAA_32 PF13654.1 EOO00004.1 - 0.0031 16.2 0.5 0.0049 15.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain Sec1 PF00995.18 EOO00004.1 - 0.0077 14.9 0.2 0.0077 14.9 0.1 1.4 2 0 0 2 2 2 1 Sec1 family zf-MIZ PF02891.15 EOO00004.1 - 0.019 14.4 8.5 0.16 11.4 5.7 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ran-binding PF05508.6 EOO00004.1 - 0.063 12.1 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Mitofilin PF09731.4 EOO00004.1 - 0.27 9.8 5.6 0.42 9.2 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-RING_6 PF14835.1 EOO00004.1 - 0.32 10.7 8.9 0.05 13.4 2.6 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Sina PF03145.11 EOO00004.1 - 0.5 9.9 14.0 0.091 12.4 2.5 2.8 2 0 0 2 2 2 0 Seven in absentia protein family Na_H_Exchanger PF00999.16 EOO00005.1 - 6.6e-37 126.9 16.9 8.8e-37 126.5 11.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glu_synthase PF01645.12 EOO00006.1 - 2.9e-159 529.8 0.0 4.5e-159 529.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EOO00006.1 - 3.5e-140 466.8 0.0 4.8e-140 466.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EOO00006.1 - 7.3e-117 389.7 0.0 1.4e-116 388.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EOO00006.1 - 4.1e-66 221.8 2.5 7.2e-66 221.0 1.7 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EOO00006.1 - 1.4e-22 79.4 0.1 3.3e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EOO00006.1 - 3.2e-16 59.8 0.0 1.2e-15 58.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO00006.1 - 1.5e-10 41.5 0.4 5.9e-05 23.2 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO00006.1 - 7.7e-09 35.4 0.3 2.6e-08 33.7 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EOO00006.1 - 1.8e-08 34.6 0.1 4.3e-05 23.8 0.0 3.5 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EOO00006.1 - 1.3e-06 27.7 0.1 2.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EOO00006.1 - 4.3e-06 25.8 0.3 4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EOO00006.1 - 2.5e-05 24.4 0.1 0.42 10.8 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EOO00006.1 - 3.7e-05 22.7 0.1 0.00026 19.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EOO00006.1 - 3.8e-05 22.3 0.1 3.8e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EOO00006.1 - 0.00011 21.3 0.1 0.00024 20.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EOO00006.1 - 0.00031 20.3 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EOO00006.1 - 0.00079 18.5 0.1 0.0061 15.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EOO00006.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DJ-1_PfpI PF01965.19 EOO00006.1 - 0.002 17.6 0.4 1.2 8.5 0.0 2.5 1 1 1 2 2 2 2 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 EOO00006.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EOO00006.1 - 0.019 13.8 1.8 0.04 12.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.14 EOO00006.1 - 0.032 12.4 0.1 5.3 5.1 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EOO00006.1 - 0.061 13.4 0.2 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.13 EOO00006.1 - 0.088 11.6 0.4 0.4 9.4 0.4 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 3HCDH_N PF02737.13 EOO00006.1 - 0.8 9.3 2.2 0.51 9.9 0.0 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Allantoicase PF03561.10 EOO00007.1 - 2.8e-109 361.2 0.1 4.1e-57 191.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat 6PF2K PF01591.13 EOO00008.1 - 7.8e-62 208.2 0.0 3.4e-45 153.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EOO00008.1 - 3e-28 98.9 0.1 7.4e-26 91.1 0.0 3.0 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EOO00008.1 - 0.0005 19.9 0.0 0.0045 16.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain Sigma70_r4_2 PF08281.7 EOO00008.1 - 0.023 14.1 0.3 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 CARD PF00619.16 EOO00008.1 - 0.28 11.0 1.3 1.7 8.5 0.2 2.6 2 1 0 2 2 2 0 Caspase recruitment domain Ank PF00023.25 EOO00009.1 - 5.3e-14 51.2 1.6 3.4e-08 32.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EOO00009.1 - 9.4e-12 45.1 0.0 3.7e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EOO00009.1 - 5.9e-11 42.2 0.7 6.5e-10 38.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TIG PF01833.19 EOO00009.1 - 1.3e-07 31.4 0.2 3.9e-07 29.9 0.1 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.1 EOO00009.1 - 4.1e-07 30.3 0.3 9.9e-06 25.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO00009.1 - 4.4e-06 26.4 0.5 0.0062 16.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat FGGY_C PF02782.11 EOO00010.1 - 1.8e-49 168.0 1.0 2.9e-49 167.3 0.7 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EOO00010.1 - 1.8e-19 70.0 0.1 3e-15 56.2 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Calcipressin PF04847.7 EOO00011.1 - 1.8e-51 174.3 0.2 2.2e-51 174.0 0.2 1.1 1 0 0 1 1 1 1 Calcipressin FixH PF05751.6 EOO00011.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 FixH tRNA-synt_2d PF01409.15 EOO00012.1 - 1.1e-47 162.2 0.3 1.3e-23 83.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EOO00012.1 - 1.4e-27 95.6 0.0 2.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain RseA_N PF03872.8 EOO00012.1 - 0.013 15.7 0.2 0.044 14.0 0.1 1.9 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain PGG PF13962.1 EOO00013.1 - 0.13 11.8 5.5 0.14 11.7 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function DoxX PF07681.7 EOO00013.1 - 6.5 7.2 8.7 0.92 9.9 0.2 2.7 2 1 1 3 3 3 0 DoxX NfeD PF01957.13 EOO00013.1 - 7.7 6.6 8.9 1 9.4 0.3 2.3 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 EOO00014.1 - 7.1e-07 28.8 1.4 0.018 14.9 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat RabGAP-TBC PF00566.13 EOO00015.1 - 4.3e-50 170.1 0.0 6.2e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sugar_tr PF00083.19 EOO00016.1 - 1.1e-100 337.4 21.5 1.3e-100 337.1 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00016.1 - 1.6e-25 89.5 32.0 5.7e-25 87.7 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EOO00016.1 - 0.19 9.8 7.0 0.19 9.8 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector RNA_pol_A_bac PF01000.21 EOO00017.1 - 1.3e-32 112.2 0.0 2.1e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EOO00017.1 - 5.5e-13 47.8 0.0 7e-13 47.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cu_bind_like PF02298.12 EOO00019.1 - 0.051 13.3 0.1 0.37 10.6 0.1 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain Fungal_trans_2 PF11951.3 EOO00020.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EOO00022.1 - 5.5e-59 199.4 0.0 7.8e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00022.1 - 9.8e-31 106.7 0.0 2.5e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EOO00022.1 - 0.029 13.1 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Asp PF00026.18 EOO00023.1 - 4.5e-65 219.9 4.7 5.2e-65 219.7 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO00023.1 - 1.2e-09 38.3 0.6 2.2e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EOO00023.1 - 0.036 13.6 0.0 0.085 12.3 0.0 1.6 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal TPK_B1_binding PF04265.9 EOO00023.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain AlgF PF11182.3 EOO00023.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Nic96 PF04097.9 EOO00024.1 - 1.2e-206 687.6 0.0 1.4e-206 687.3 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Rad51 PF08423.6 EOO00025.1 - 1.9e-23 82.7 0.0 2.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EOO00025.1 - 2.1e-11 43.6 0.0 3.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EOO00025.1 - 1.8e-07 30.5 0.2 7.2e-05 22.0 0.0 2.0 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 EOO00025.1 - 2e-05 23.8 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 EOO00025.1 - 0.024 13.4 0.1 0.048 12.5 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.1 EOO00025.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EOO00025.1 - 0.25 10.6 0.2 0.51 9.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Bac_rhodopsin PF01036.13 EOO00026.1 - 5.6e-27 94.4 27.3 8e-27 93.9 18.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cpn60_TCP1 PF00118.19 EOO00027.1 - 4.4e-161 536.7 0.5 5e-161 536.5 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GRAB PF10375.4 EOO00028.1 - 2.3e-08 33.3 0.0 4.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 EOO00028.1 - 2.5e-06 27.3 61.3 0.0056 16.5 12.4 3.8 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EOO00028.1 - 8e-05 22.2 56.1 0.01 15.3 12.5 2.3 1 1 1 2 2 2 2 Intermediate filament protein WEMBL PF05701.6 EOO00028.1 - 0.0028 16.1 29.3 0.0028 16.1 20.3 3.2 2 1 1 3 3 3 1 Weak chloroplast movement under blue light MAD PF05557.8 EOO00028.1 - 0.003 15.7 51.1 0.0084 14.2 11.9 3.2 1 1 2 3 3 3 2 Mitotic checkpoint protein Tup_N PF08581.5 EOO00028.1 - 0.0056 16.8 2.0 0.0056 16.8 1.4 5.4 2 1 3 5 5 5 1 Tup N-terminal Reo_sigmaC PF04582.7 EOO00028.1 - 0.014 14.5 16.8 0.56 9.3 0.9 3.2 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EOO00028.1 - 0.024 12.3 61.1 0.075 10.7 42.4 1.8 1 1 0 1 1 1 0 Myosin tail Laminin_I PF06008.9 EOO00028.1 - 0.048 12.9 47.6 0.51 9.6 6.3 2.8 1 1 1 2 2 2 0 Laminin Domain I DUF4618 PF15397.1 EOO00028.1 - 0.14 11.4 39.3 0.21 10.8 18.2 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EOO00028.1 - 0.22 11.3 16.0 0.91 9.3 0.8 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 EOO00028.1 - 0.78 9.6 52.7 0.092 12.7 13.6 3.5 2 2 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.6 EOO00028.1 - 1.4 8.8 20.4 4.5 7.2 0.4 6.1 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EOO00028.1 - 1.6 9.0 18.6 12 6.1 0.8 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EOO00028.1 - 2.2 8.0 23.8 3.4 7.4 1.5 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EOO00028.1 - 3.2 7.4 36.7 0.69 9.5 1.2 3.7 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 COG2 PF06148.6 EOO00028.1 - 7.6 6.4 35.4 0.19 11.6 3.6 4.3 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cys_Met_Meta_PP PF01053.15 EOO00029.1 - 1e-150 501.3 0.0 1.1e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EOO00029.1 - 1.8e-13 50.2 0.3 2.9e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EOO00029.1 - 1.1e-10 40.9 0.0 2.6e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EOO00029.1 - 9.4e-09 34.4 0.2 1.7e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EOO00029.1 - 3.2e-08 33.0 0.0 5.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EOO00029.1 - 0.00014 20.2 0.1 0.00019 19.8 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EOO00029.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SelA PF03841.8 EOO00029.1 - 0.033 12.9 0.2 0.097 11.3 0.2 1.7 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Peptidase_M13 PF01431.16 EOO00030.1 - 5.7e-54 182.4 0.1 8.9e-54 181.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 EOO00030.1 - 1.3e-39 136.3 0.0 1.7e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Ssl1 PF04056.9 EOO00031.1 - 3.3e-72 242.1 0.0 4.4e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EOO00031.1 - 3.6e-16 58.9 6.1 3.6e-16 58.9 4.2 3.3 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EOO00031.1 - 1.1e-08 35.4 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EOO00031.1 - 0.15 11.3 3.5 0.28 10.3 2.4 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 Aldolase_II PF00596.16 EOO00032.1 - 1.3e-41 142.2 1.0 1.7e-41 141.8 0.7 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ufd2P_core PF10408.4 EOO00033.1 - 5.2e-197 655.9 5.2 6.2e-197 655.7 3.6 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EOO00033.1 - 3.9e-23 81.1 0.6 1.3e-22 79.4 0.4 2.0 1 0 0 1 1 1 1 U-box domain OmpH PF03938.9 EOO00033.1 - 0.13 12.1 4.9 0.41 10.5 3.4 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.15 EOO00033.1 - 2.2 8.0 9.9 1.6 8.5 3.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit Glyoxalase PF00903.20 EOO00034.1 - 1.5e-16 60.5 0.0 5.7e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EOO00034.1 - 1.2e-09 38.0 0.0 0.002 18.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EOO00034.1 - 2.1e-09 37.9 0.0 0.0018 18.8 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EOO00034.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EOO00034.1 - 0.00055 19.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Phi-29_GP4 PF05464.6 EOO00034.1 - 0.11 12.3 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Pkinase PF00069.20 EOO00035.1 - 7.8e-10 38.3 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00035.1 - 0.0035 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Citrate_synt PF00285.16 EOO00036.1 - 1e-102 343.5 0.0 1.3e-102 343.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EOO00036.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Sec6 PF06046.8 EOO00037.1 - 9.5e-170 565.3 11.7 1.3e-169 564.9 8.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EOO00037.1 - 9.4e-06 24.6 3.3 9.4e-06 24.6 2.3 2.8 3 0 0 3 3 3 1 Vps53-like, N-terminal MutS_III PF05192.13 EOO00037.1 - 0.044 13.5 1.9 0.4 10.4 1.2 2.9 1 1 0 1 1 1 0 MutS domain III Sec20 PF03908.8 EOO00037.1 - 0.14 11.9 2.7 0.43 10.3 0.3 3.0 2 1 1 3 3 3 0 Sec20 DUF2450 PF10475.4 EOO00037.1 - 0.21 10.4 8.6 0.26 10.1 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) FAD_binding_2 PF00890.19 EOO00037.1 - 0.22 10.3 0.1 0.69 8.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DIL PF01843.14 EOO00038.1 - 1.9e-19 69.4 2.7 5.7e-13 48.6 0.1 2.8 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 EOO00038.1 - 1.7e-16 60.2 0.2 6e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EOO00038.1 - 2.5e-16 58.5 0.1 1.1e-05 24.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EOO00038.1 - 1.1e-11 44.5 0.1 6.8e-05 22.9 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO00038.1 - 1.3e-10 41.4 0.3 9.7e-05 22.7 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO00038.1 - 6.9e-09 35.0 0.0 0.02 15.0 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat DUF4479 PF14794.1 EOO00038.1 - 0.024 14.1 0.7 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) HSP70 PF00012.15 EOO00039.1 - 1.8e-08 32.8 0.2 1.4e-07 29.8 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein DUF4618 PF15397.1 EOO00041.1 - 0.0022 17.3 2.0 0.0034 16.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.6 EOO00041.1 - 0.0094 14.6 5.3 0.013 14.1 3.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec2p PF06428.6 EOO00041.1 - 0.021 14.6 6.5 0.022 14.6 0.1 2.6 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Atg14 PF10186.4 EOO00041.1 - 0.022 13.7 3.9 0.031 13.2 2.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 End3 PF12761.2 EOO00041.1 - 0.028 14.0 3.4 0.042 13.4 2.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ORC6 PF05460.8 EOO00041.1 - 0.04 13.0 3.2 0.05 12.6 2.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mnd1 PF03962.10 EOO00041.1 - 0.09 12.4 4.7 0.14 11.8 3.3 1.2 1 0 0 1 1 1 0 Mnd1 family Bap31 PF05529.7 EOO00041.1 - 0.096 12.1 0.8 0.16 11.4 0.5 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TBPIP PF07106.8 EOO00041.1 - 0.1 12.1 2.8 0.22 11.0 1.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 EOO00041.1 - 0.11 11.8 4.4 0.68 9.3 0.1 2.2 1 1 0 2 2 2 0 Phage minor structural protein GP20 Lebercilin PF15619.1 EOO00041.1 - 0.12 11.7 11.2 1.7 8.0 1.3 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 EOO00041.1 - 0.16 11.5 12.1 0.3 10.6 8.4 1.3 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EOO00041.1 - 0.19 11.5 9.4 0.36 10.6 6.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFIIA PF03153.8 EOO00041.1 - 0.28 11.0 4.1 0.35 10.7 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EOO00041.1 - 0.31 10.4 8.0 0.39 10.0 5.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF4238 PF14022.1 EOO00041.1 - 0.31 10.2 4.0 0.57 9.4 2.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) ADIP PF11559.3 EOO00041.1 - 0.32 10.8 6.5 0.49 10.2 4.1 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EOO00041.1 - 0.69 9.8 10.3 3 7.7 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CENP-Q PF13094.1 EOO00041.1 - 0.93 9.4 11.3 0.14 12.1 2.8 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.7 EOO00041.1 - 1 9.1 8.9 2.7 7.7 2.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 EOO00041.1 - 1.1 7.0 4.3 1.8 6.3 3.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 EOO00041.1 - 1.1 8.5 13.4 0.057 12.8 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) ATG16 PF08614.6 EOO00041.1 - 1.3 8.7 14.4 1 9.1 4.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EOO00041.1 - 1.8 8.2 8.3 0.25 11.1 1.6 2.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EOO00041.1 - 2.6 7.0 8.2 2.3 7.1 4.8 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Apc15p PF05841.6 EOO00042.1 - 1e-19 71.4 0.6 1e-19 71.4 0.4 2.7 3 1 0 3 3 3 1 Apc15p protein DUF2782 PF11191.3 EOO00042.1 - 1.2 9.1 3.8 2.4 8.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) DUF1168 PF06658.7 EOO00044.1 - 4.7e-41 139.6 10.2 6.6e-41 139.1 7.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNase_H2-Ydr279 PF09468.5 EOO00044.1 - 3.7 6.6 6.5 11 5.0 4.9 1.4 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Complex1_LYR PF05347.10 EOO00045.1 - 1.8e-07 30.8 1.3 1.8e-07 30.8 0.9 2.2 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EOO00045.1 - 0.0064 16.6 3.7 0.011 15.9 2.4 1.7 1 1 0 1 1 1 1 Complex1_LYR-like GPP34 PF05719.6 EOO00045.1 - 0.12 12.4 2.9 0.13 12.3 2.0 1.1 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Chs3p PF12271.3 EOO00046.1 - 2.1e-86 289.5 14.0 2.8e-86 289.1 9.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2637 PF10935.3 EOO00046.1 - 0.12 12.2 2.6 1.3 8.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2637) DUF4059 PF13268.1 EOO00046.1 - 0.24 11.6 0.2 0.24 11.6 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4059) DUF2678 PF10856.3 EOO00046.1 - 2.4 7.8 10.0 0.03 14.0 0.9 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2678) DUF973 PF06157.6 EOO00046.1 - 2.8 6.8 16.7 0.046 12.6 2.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF973) Ribosomal_L15e PF00827.12 EOO00047.1 - 6.1e-91 303.1 12.4 7e-91 302.9 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 IKI3 PF04762.7 EOO00048.1 - 6.6e-248 825.1 0.0 7e-167 556.9 0.0 2.1 1 1 1 2 2 2 2 IKI3 family TPR_8 PF13181.1 EOO00048.1 - 0.0057 16.3 0.1 0.086 12.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EOO00048.1 - 0.012 15.4 6.9 0.37 10.8 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EOO00048.1 - 0.34 10.5 2.7 0.5 10.0 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EOO00048.1 - 0.41 10.5 3.1 1.9 8.4 0.2 3.4 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00048.1 - 3.1 8.5 9.5 1.6 9.4 2.6 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 EOO00049.1 - 6.8e-34 117.2 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3984 PF13136.1 EOO00050.1 - 1.2e-27 97.0 1.3 1.2e-27 97.0 0.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) His_Phos_1 PF00300.17 EOO00051.1 - 3.7e-32 111.6 0.4 7e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EOO00051.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PUF PF00806.14 EOO00052.1 - 7.9e-60 195.1 12.6 6.5e-08 31.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 EOO00052.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) NUDE_C PF04880.8 EOO00052.1 - 0.27 11.5 9.0 0.028 14.8 2.1 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Tnp_P_element PF12017.3 EOO00052.1 - 0.62 9.2 3.0 2.1 7.5 1.6 2.0 2 0 0 2 2 2 0 Transposase protein DUF2012 PF09430.5 EOO00053.1 - 6.3e-24 84.1 0.0 8.4e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CAP_GLY PF01302.20 EOO00054.1 - 9.7e-23 79.6 1.2 1.5e-22 79.0 0.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Cytochrom_B561 PF03188.11 EOO00055.1 - 3.6e-19 68.9 3.7 3.6e-19 68.9 2.6 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Sdh_cyt PF01127.17 EOO00055.1 - 0.94 9.3 17.5 0.14 11.9 2.3 3.0 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Tropomyosin_1 PF12718.2 EOO00056.1 - 0.13 12.1 8.0 0.21 11.4 5.5 1.3 1 0 0 1 1 1 0 Tropomyosin like RNA_pol_Rpb2_6 PF00562.23 EOO00057.1 - 1e-116 389.9 0.0 1.7e-116 389.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EOO00057.1 - 1.6e-51 174.1 0.5 3.6e-51 172.9 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EOO00057.1 - 9.3e-30 102.7 0.3 2.3e-29 101.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EOO00057.1 - 1.2e-28 99.8 0.2 3e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EOO00057.1 - 2.2e-21 75.3 0.0 4.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EOO00057.1 - 7.1e-20 70.5 0.2 1.9e-19 69.2 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EOO00057.1 - 2.3e-13 49.8 0.2 9.1e-13 47.9 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 zf-RING_2 PF13639.1 EOO00058.1 - 1.9e-11 43.5 3.9 2.8e-11 43.0 2.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EOO00058.1 - 5.9e-06 26.2 0.7 1.2e-05 25.3 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EOO00058.1 - 2.5e-05 23.8 2.1 4.3e-05 23.0 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO00058.1 - 5e-05 23.2 3.3 8.6e-05 22.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO00058.1 - 0.00064 19.4 1.3 0.0011 18.6 0.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EOO00058.1 - 0.051 13.2 1.6 0.085 12.5 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EOO00058.1 - 2.2 8.0 4.7 11 5.8 2.7 2.2 1 1 1 2 2 2 0 PHD-finger HATPase_c PF02518.21 EOO00059.1 - 1.1e-24 86.2 0.2 2.6e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EOO00059.1 - 3.1e-22 78.6 0.1 6.9e-21 74.3 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EOO00059.1 - 3.9e-21 74.8 1.9 4.4e-21 74.6 0.1 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain RRM_5 PF13893.1 EOO00060.1 - 1.1e-07 31.6 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EOO00060.1 - 2.6e-06 26.9 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00060.1 - 2.2e-05 24.3 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EOO00060.1 - 0.00054 20.1 0.1 0.0023 18.1 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Mito_carr PF00153.22 EOO00061.1 - 5.4e-29 99.7 5.8 7.1e-12 44.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Romo1 PF10247.4 EOO00061.1 - 0.11 12.7 6.1 0.52 10.5 1.8 2.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 GFO_IDH_MocA PF01408.17 EOO00062.1 - 2.3e-19 70.0 0.5 3.9e-19 69.3 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EOO00062.1 - 0.0009 19.6 0.2 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EOO00062.1 - 0.0076 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SNARE PF05739.14 EOO00063.1 - 2.4e-09 36.7 2.2 3.1e-09 36.3 1.5 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EOO00063.1 - 0.005 16.3 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Hpt PF01627.18 EOO00064.1 - 2.2e-12 46.8 0.1 4.7e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Hpt domain DUF3425 PF11905.3 EOO00065.1 - 2.3e-34 118.1 1.1 4.2e-34 117.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) F-box-like PF12937.2 EOO00066.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.4 3 0 0 3 3 3 0 F-box-like Aa_trans PF01490.13 EOO00067.1 - 3.4e-71 239.8 29.2 4.1e-71 239.6 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EOO00067.1 - 0.0072 14.9 30.9 0.029 12.9 21.2 1.8 1 1 0 1 1 1 1 Amino acid permease SMN PF06003.7 EOO00068.1 - 5.6e-06 25.6 3.5 0.00046 19.3 0.2 2.4 2 1 0 2 2 2 2 Survival motor neuron protein (SMN) TPT PF03151.11 EOO00069.1 - 3.7e-28 98.1 13.3 3.7e-28 98.1 9.2 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EOO00069.1 - 0.031 14.3 32.3 0.12 12.4 7.4 2.9 3 0 0 3 3 3 0 EamA-like transporter family UAA PF08449.6 EOO00069.1 - 0.035 13.0 24.7 0.28 10.0 16.8 2.1 1 1 0 1 1 1 0 UAA transporter family RFC1 PF08519.7 EOO00070.1 - 1.4e-54 184.0 0.1 4.8e-54 182.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EOO00070.1 - 5.6e-13 48.8 0.0 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EOO00070.1 - 3.4e-09 37.0 0.0 9.1e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EOO00070.1 - 5.6e-07 28.6 0.0 9.9e-07 27.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EOO00070.1 - 4.7e-05 23.5 0.0 0.00077 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EOO00070.1 - 0.00033 21.4 0.0 0.00033 21.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.1 EOO00070.1 - 0.0012 18.5 0.1 0.0036 17.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EOO00070.1 - 0.0023 18.2 0.1 0.0023 18.2 0.1 3.0 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.2 EOO00070.1 - 0.0065 16.2 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain AAA_16 PF13191.1 EOO00070.1 - 0.0075 16.2 0.0 0.05 13.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EOO00070.1 - 0.013 15.0 0.0 0.033 13.6 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.1 EOO00070.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EOO00070.1 - 0.023 14.5 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EOO00070.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EOO00070.1 - 0.04 13.8 1.7 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EOO00070.1 - 0.055 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EOO00070.1 - 0.098 12.3 0.2 0.27 10.9 0.0 1.8 1 1 0 2 2 2 0 NTPase NACHT PF05729.7 EOO00070.1 - 0.11 12.0 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain LtrA PF06772.6 EOO00072.1 - 4.5e-07 29.1 11.0 2.5e-06 26.6 7.6 2.1 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PIP5K PF01504.13 EOO00073.1 - 0.00026 20.1 0.0 0.00049 19.2 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Aldo_ket_red PF00248.16 EOO00074.1 - 6.7e-17 61.2 0.0 8.4e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AfsA PF03756.8 EOO00074.1 - 0.07 12.8 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain Glyco_hydro_cc PF11790.3 EOO00075.1 - 4.1e-55 186.8 0.2 6.7e-55 186.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Phosphoprotein PF00922.12 EOO00075.1 - 0.87 8.7 6.6 1.4 8.1 4.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein CAF-1_p150 PF11600.3 EOO00075.1 - 4.5 6.5 7.0 7.1 5.9 4.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_BLLF1 PF05109.8 EOO00075.1 - 7.4 4.3 29.1 10 3.9 20.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AKAP7_NLS PF10469.4 EOO00076.1 - 1.1e-16 61.2 0.0 1.2e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Mito_carr PF00153.22 EOO00077.1 - 3e-52 174.2 0.4 2.2e-17 62.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CHZ PF09649.5 EOO00079.1 - 1.6e-15 55.9 2.8 1.6e-15 55.9 1.9 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ SAPS PF04499.10 EOO00079.1 - 9.2 4.7 9.5 9.4 4.7 6.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein E1-E2_ATPase PF00122.15 EOO00080.1 - 2e-63 213.5 6.6 2e-63 213.5 4.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EOO00080.1 - 8.7e-23 81.8 0.0 2e-22 80.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EOO00080.1 - 6.6e-13 49.2 0.0 1.9e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EOO00080.1 - 8.8e-12 44.3 0.0 2.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EOO00080.1 - 0.0011 18.5 0.1 0.0028 17.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO00080.1 - 0.0075 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Methyltransf_11 PF08241.7 EOO00081.1 - 8.1e-12 45.4 0.0 3e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00081.1 - 1.5e-08 35.0 0.0 4.1e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO00081.1 - 7e-07 29.1 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO00081.1 - 8.5e-07 29.2 0.3 7.8e-06 26.1 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO00081.1 - 9.4e-06 26.1 0.4 2e-05 25.1 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00081.1 - 0.00011 21.8 0.0 0.059 12.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EOO00081.1 - 0.0007 19.6 0.7 0.0018 18.2 0.3 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF4024 PF13216.1 EOO00081.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) HemY_N PF07219.8 EOO00081.1 - 0.31 10.5 2.5 0.26 10.8 0.2 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Cauli_VI PF01693.11 EOO00082.1 - 6.9e-29 99.6 6.9 1.2e-14 54.0 0.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EOO00082.1 - 2.6e-26 92.5 0.1 4.1e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 RNase H KOW PF00467.24 EOO00083.1 - 5.3e-06 25.9 0.3 1.1e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 KOW motif Myb_DNA-bind_5 PF13873.1 EOO00083.1 - 9.7 6.1 10.5 1.3 8.9 2.1 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Mito_carr PF00153.22 EOO00084.1 - 1.9e-46 155.7 6.4 1.4e-17 63.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L27e PF01777.13 EOO00085.1 - 6.7e-37 125.4 4.3 8.6e-37 125.1 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EOO00085.1 - 0.0043 16.7 1.8 0.012 15.2 1.2 1.8 1 0 0 1 1 1 1 KOW motif VTC PF09359.5 EOO00086.1 - 2.4e-92 308.9 0.7 3.9e-92 308.2 0.5 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EOO00086.1 - 3.9e-18 66.2 16.1 4.6e-09 36.4 0.9 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EOO00086.1 - 1.2e-09 38.2 2.9 2.7e-09 37.0 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cob_adeno_trans PF01923.13 EOO00086.1 - 0.14 11.9 0.8 1.3 8.7 0.1 2.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase WW PF00397.21 EOO00087.1 - 4.9e-07 29.4 6.3 9.2e-07 28.6 4.4 1.5 1 0 0 1 1 1 1 WW domain NAD_binding_8 PF13450.1 EOO00088.1 - 4.2e-07 29.8 0.0 9.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EOO00088.1 - 3.8e-05 22.9 0.0 0.00012 21.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EOO00088.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EOO00088.1 - 0.021 13.8 0.1 0.33 9.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EOO00088.1 - 0.07 13.1 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO00088.1 - 0.071 12.9 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CFIA_Pcf11 PF11526.3 EOO00089.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.1 EOO00089.1 - 0.049 13.9 1.4 2.1 8.8 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Transposase_21 PF02992.9 EOO00089.1 - 0.051 12.6 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Transposase family tnp2 RRN7 PF11781.3 EOO00089.1 - 0.082 12.4 1.4 0.23 10.9 0.2 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 EOO00089.1 - 0.13 11.9 4.7 2.1 8.1 1.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Prok-RING_1 PF14446.1 EOO00089.1 - 9.8 6.0 7.5 28 4.5 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Sugar_tr PF00083.19 EOO00090.1 - 1.8e-107 359.7 19.1 2.1e-107 359.4 13.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00090.1 - 1.1e-23 83.5 29.8 1.1e-23 83.5 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1269 PF06897.7 EOO00090.1 - 5.1 7.1 7.3 1.1 9.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) MFS_1 PF07690.11 EOO00091.1 - 5.9e-18 64.6 19.7 7.4e-18 64.3 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EOO00091.1 - 0.00028 20.6 0.6 0.0012 18.6 0.4 2.1 1 0 0 1 1 1 1 MFS_1 like family GrpE PF01025.14 EOO00092.1 - 9.4e-50 168.3 8.0 1.2e-49 168.0 5.6 1.1 1 0 0 1 1 1 1 GrpE ORC4_C PF14629.1 EOO00092.1 - 0.05 12.9 0.2 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Velvet PF11754.3 EOO00094.1 - 4.7e-67 225.5 0.2 8.1e-67 224.7 0.0 1.4 2 0 0 2 2 2 1 Velvet factor Ras PF00071.17 EOO00095.1 - 5.6e-56 188.4 0.0 6.4e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO00095.1 - 1e-15 58.2 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO00095.1 - 3.8e-07 29.5 0.0 6.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EOO00095.1 - 0.0012 18.3 0.0 0.0053 16.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EOO00095.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EOO00095.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EOO00095.1 - 0.13 11.7 0.0 11 5.4 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MARVEL PF01284.18 EOO00096.1 - 3.4e-18 65.8 16.9 4.3e-18 65.5 11.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_M3 PF01432.15 EOO00098.1 - 5.2e-71 240.0 5.9 6.1e-44 150.8 0.3 2.1 1 1 1 2 2 2 2 Peptidase family M3 RE_SinI PF09570.5 EOO00098.1 - 0.1 11.5 0.4 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 SinI restriction endonuclease MFS_1 PF07690.11 EOO00099.1 - 1.8e-30 105.8 28.3 1.8e-30 105.8 19.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_10 PF13460.1 EOO00100.1 - 3.1e-11 43.6 0.2 9.9e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO00100.1 - 3.7e-09 36.3 0.2 9.4e-09 35.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EOO00100.1 - 8.7e-05 22.4 0.1 0.0002 21.3 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EOO00100.1 - 0.00018 20.2 0.0 0.00029 19.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EOO00100.1 - 0.00043 19.6 0.2 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EOO00100.1 - 0.0074 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EOO00100.1 - 0.013 15.2 0.1 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 KR domain Acetyltransf_6 PF13480.1 EOO00100.1 - 0.073 13.0 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CAP PF00188.21 EOO00101.1 - 1.2e-19 71.0 0.7 1.6e-19 70.6 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bys1 PF04681.7 EOO00102.1 - 4.5e-13 49.2 0.2 1.4e-12 47.5 0.1 1.8 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein p450 PF00067.17 EOO00103.1 - 1.9e-38 132.2 0.0 2.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Clp1 PF06807.9 EOO00107.1 - 3.2e-22 79.2 0.0 5.1e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EOO00107.1 - 2.2e-05 24.1 0.0 7.5e-05 22.4 0.0 2.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EOO00107.1 - 8e-05 22.2 0.0 0.00034 20.2 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EOO00107.1 - 0.0015 18.4 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EOO00107.1 - 0.002 17.3 0.0 0.0068 15.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EOO00107.1 - 0.011 15.1 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EOO00107.1 - 0.012 15.6 0.1 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EOO00107.1 - 0.039 13.7 0.0 7.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.5 EOO00107.1 - 0.077 12.2 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EOO00107.1 - 0.1 13.1 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein tRNA-synt_2 PF00152.15 EOO00111.1 - 4.1e-78 262.4 0.0 7.8e-78 261.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EOO00111.1 - 6.3e-21 74.4 0.0 1.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EOO00111.1 - 4.5e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EOO00111.1 - 0.017 14.3 0.0 4.9 6.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Ribosomal_L1 PF00687.16 EOO00112.1 - 4.8e-56 189.5 2.3 4.8e-56 189.5 1.6 2.2 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family LRAT PF04970.8 EOO00112.1 - 0.11 12.4 1.6 0.24 11.3 0.0 2.4 3 1 0 3 3 3 0 Lecithin retinol acyltransferase CDC45 PF02724.9 EOO00112.1 - 1.3 7.0 19.1 2.1 6.2 13.2 1.3 1 0 0 1 1 1 0 CDC45-like protein ADH_zinc_N_2 PF13602.1 EOO00113.1 - 3.8e-16 60.1 0.0 4.4e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO00113.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.10 EOO00114.1 - 6.7e-156 519.2 31.1 7.8e-156 519.0 21.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 EOO00115.1 - 0.0091 14.7 1.3 0.011 14.4 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OB_NTP_bind PF07717.11 EOO00116.1 - 7.6e-28 96.6 0.0 7e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EOO00116.1 - 9.7e-27 92.9 0.1 9.7e-27 92.9 0.1 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EOO00116.1 - 4.8e-12 45.5 0.0 1.4e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EOO00116.1 - 1.3e-09 38.0 0.7 3.3e-09 36.6 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EOO00116.1 - 1.9e-07 30.7 0.1 3.9e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EOO00116.1 - 1.9e-06 28.0 0.0 5.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EOO00116.1 - 0.00019 20.4 0.0 0.00045 19.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EOO00116.1 - 0.0011 18.5 0.1 0.0029 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.4 EOO00116.1 - 0.012 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EOO00116.1 - 0.014 14.8 0.1 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EOO00116.1 - 0.017 14.8 0.0 0.07 12.8 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EOO00116.1 - 0.022 14.4 0.1 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 EOO00116.1 - 0.039 13.8 0.1 0.24 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EOO00116.1 - 0.053 12.9 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EOO00116.1 - 0.065 13.5 0.2 2.6 8.3 0.1 2.8 1 1 1 2 2 2 0 ABC transporter NB-ARC PF00931.17 EOO00116.1 - 0.073 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EOO00116.1 - 0.14 12.3 0.3 1.1 9.4 0.2 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Myosin_head PF00063.16 EOO00116.1 - 0.16 9.9 0.0 0.25 9.3 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Med9 PF07544.8 EOO00117.1 - 0.072 12.8 2.6 7.4 6.3 0.5 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIVA PF05103.8 EOO00117.1 - 0.099 12.7 0.1 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 DivIVA protein zf-RING_2 PF13639.1 EOO00118.1 - 1.8e-09 37.2 8.2 3.4e-09 36.3 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EOO00118.1 - 3e-08 33.6 2.6 6.1e-08 32.6 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EOO00118.1 - 7.9e-06 25.7 11.3 1.3e-05 25.0 6.7 2.2 2 1 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EOO00118.1 - 3.7e-05 23.4 2.2 8.6e-05 22.3 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EOO00118.1 - 0.00054 19.9 8.8 0.0011 18.9 6.1 1.5 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 EOO00118.1 - 0.00055 19.6 3.8 0.00055 19.6 2.7 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 EOO00118.1 - 0.0016 18.0 5.6 0.0028 17.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO00118.1 - 0.0017 17.9 10.8 0.0031 17.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO00118.1 - 0.0077 16.2 9.3 0.015 15.3 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EOO00118.1 - 0.11 12.5 8.3 0.2 11.7 5.8 1.5 1 0 0 1 1 1 0 RING-like domain Baculo_RING PF05883.6 EOO00118.1 - 0.11 12.2 2.2 0.23 11.2 1.5 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.1 EOO00118.1 - 0.66 9.7 9.5 1.1 8.9 6.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EOO00118.1 - 1.2 8.7 8.2 22 4.7 5.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EOO00118.1 - 1.5 8.5 7.7 2.7 7.7 5.4 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EOO00118.1 - 4.1 7.2 7.0 20 5.0 5.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Peptidase_S8 PF00082.17 EOO00119.1 - 2.8e-49 167.7 2.5 4.1e-49 167.2 1.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EOO00119.1 - 1.5e-05 25.3 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Laminin_II PF06009.7 EOO00120.1 - 9.5e-06 25.4 6.7 9.5e-06 25.4 0.9 2.1 2 0 0 2 2 2 1 Laminin Domain II ATG16 PF08614.6 EOO00120.1 - 1.7e-05 24.7 0.9 2.1e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EOO00120.1 - 2.2e-05 23.8 8.4 0.012 14.7 1.7 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Spc7 PF08317.6 EOO00120.1 - 5.5e-05 21.9 0.6 7.5e-05 21.5 0.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin PF00261.15 EOO00120.1 - 0.00022 20.3 2.0 0.00066 18.8 1.0 1.8 1 1 0 2 2 2 1 Tropomyosin FlxA PF14282.1 EOO00120.1 - 0.00029 20.7 1.4 0.004 17.0 0.3 2.4 2 0 0 2 2 2 1 FlxA-like protein Med9 PF07544.8 EOO00120.1 - 0.00033 20.3 1.0 0.0019 17.8 0.9 2.1 2 1 0 2 2 1 1 RNA polymerase II transcription mediator complex subunit 9 PspA_IM30 PF04012.7 EOO00120.1 - 0.00034 20.0 5.5 0.27 10.5 0.3 2.1 1 1 1 2 2 2 2 PspA/IM30 family NPV_P10 PF05531.7 EOO00120.1 - 0.00054 20.1 7.5 0.0081 16.3 2.1 2.5 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 EOO00120.1 - 0.00066 19.3 1.3 0.0085 15.7 0.4 2.3 2 0 0 2 2 2 1 Prefoldin subunit Baculo_PEP_C PF04513.7 EOO00120.1 - 0.00082 19.2 9.0 0.11 12.2 0.3 2.3 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 EOO00120.1 - 0.001 18.6 1.6 0.023 14.2 1.1 2.0 1 1 1 2 2 2 1 Intermediate filament protein BLOC1_2 PF10046.4 EOO00120.1 - 0.0012 18.9 1.4 0.016 15.3 0.3 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.1 EOO00120.1 - 0.0015 17.9 0.5 0.087 12.1 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 EOO00120.1 - 0.0023 17.8 0.6 0.0044 16.8 0.4 1.5 1 0 0 1 1 1 1 Tropomyosin like AAA_13 PF13166.1 EOO00120.1 - 0.0027 16.2 0.3 0.0033 15.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 EOO00120.1 - 0.0038 17.0 6.5 0.99 9.3 1.0 3.2 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Mitofilin PF09731.4 EOO00120.1 - 0.0082 14.8 1.8 0.0099 14.5 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Myosin_tail_1 PF01576.14 EOO00120.1 - 0.0087 13.8 1.1 0.011 13.4 0.7 1.2 1 0 0 1 1 1 1 Myosin tail MCPsignal PF00015.16 EOO00120.1 - 0.009 15.5 5.8 0.009 15.5 4.0 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc24 PF08286.6 EOO00120.1 - 0.0097 15.5 1.5 0.021 14.4 0.4 1.9 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EOO00120.1 - 0.011 15.4 0.5 0.34 10.7 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF869 PF05911.6 EOO00120.1 - 0.011 13.9 0.6 0.014 13.6 0.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 EOO00120.1 - 0.012 15.4 0.4 0.037 13.8 0.2 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_S5_C PF03719.10 EOO00120.1 - 0.014 14.6 1.1 1.1 8.6 0.3 2.8 2 1 1 3 3 2 0 Ribosomal protein S5, C-terminal domain IncA PF04156.9 EOO00120.1 - 0.015 14.8 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EOO00120.1 - 0.02 14.7 1.8 0.063 13.0 1.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.5 EOO00120.1 - 0.02 14.8 8.5 2.1 8.2 0.1 3.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 EOO00120.1 - 0.021 15.2 0.4 0.12 12.7 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal GAS PF13851.1 EOO00120.1 - 0.021 13.9 0.1 0.053 12.7 0.0 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.2 EOO00120.1 - 0.022 14.0 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EzrA PF06160.7 EOO00120.1 - 0.024 12.8 1.6 0.055 11.6 0.1 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DivIC PF04977.10 EOO00120.1 - 0.027 13.9 1.7 0.16 11.4 0.8 2.3 2 1 0 2 2 1 0 Septum formation initiator DUF4407 PF14362.1 EOO00120.1 - 0.029 13.3 5.4 0.37 9.7 3.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 EOO00120.1 - 0.029 14.2 10.2 0.96 9.3 0.2 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DMPK_coil PF08826.5 EOO00120.1 - 0.032 14.1 1.2 0.073 12.9 0.8 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like Fib_alpha PF08702.5 EOO00120.1 - 0.033 14.3 2.4 0.41 10.7 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DHC_N1 PF08385.7 EOO00120.1 - 0.034 12.5 0.0 0.039 12.3 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 FliD_N PF02465.13 EOO00120.1 - 0.036 14.4 5.3 2.2 8.6 0.0 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ADIP PF11559.3 EOO00120.1 - 0.043 13.7 0.8 0.98 9.3 0.7 2.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DASH_Duo1 PF08651.5 EOO00120.1 - 0.047 13.2 0.4 18 5.0 0.0 3.2 2 1 2 4 4 3 0 DASH complex subunit Duo1 USP8_interact PF08941.5 EOO00120.1 - 0.054 12.8 0.6 0.16 11.2 0.1 1.9 2 0 0 2 2 2 0 USP8 interacting Sec2p PF06428.6 EOO00120.1 - 0.056 13.2 1.8 0.52 10.1 0.2 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p MCP_N PF05581.7 EOO00120.1 - 0.059 13.5 1.2 0.093 12.8 0.4 1.7 1 1 0 1 1 1 0 Vibrio chemotaxis protein N terminus DUF3450 PF11932.3 EOO00120.1 - 0.061 12.5 3.4 0.2 10.9 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 EOO00120.1 - 0.068 11.0 0.5 0.12 10.2 0.2 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1319 PF07028.6 EOO00120.1 - 0.082 13.1 0.8 0.27 11.4 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) SlyX PF04102.7 EOO00120.1 - 0.082 13.2 3.5 0.23 11.8 1.7 2.1 1 1 1 2 2 2 0 SlyX RapA_C PF12137.3 EOO00120.1 - 0.084 11.6 2.4 0.11 11.2 1.5 1.3 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal COG5 PF10392.4 EOO00120.1 - 0.091 12.7 0.4 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 APG6 PF04111.7 EOO00120.1 - 0.094 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 EOO00120.1 - 0.097 12.8 1.3 0.33 11.1 0.3 2.1 2 0 0 2 2 2 0 Syntaxin Trns_repr_metal PF02583.12 EOO00120.1 - 0.1 12.8 1.5 0.73 10.0 0.2 2.5 2 1 0 2 2 2 0 Metal-sensitive transcriptional repressor Striatin PF08232.7 EOO00120.1 - 0.1 12.9 0.1 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 Striatin family TBPIP PF07106.8 EOO00120.1 - 0.1 12.1 2.6 0.39 10.2 1.2 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EOO00120.1 - 0.1 12.6 2.3 0.35 10.8 0.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Urease_gamma PF00547.13 EOO00120.1 - 0.12 12.4 3.0 0.12 12.4 0.3 2.2 2 1 0 2 2 2 0 Urease, gamma subunit DUF4140 PF13600.1 EOO00120.1 - 0.12 12.8 4.9 0.3 11.5 0.7 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lectin_N PF03954.9 EOO00120.1 - 0.12 11.7 0.8 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Sec34 PF04136.10 EOO00120.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Sec34-like family DUF4544 PF15077.1 EOO00120.1 - 0.12 11.8 0.8 0.23 10.9 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4544) COG2 PF06148.6 EOO00120.1 - 0.14 11.9 3.7 0.83 9.5 0.8 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.6 EOO00120.1 - 0.15 11.4 3.8 0.25 10.7 1.4 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ISG65-75 PF11727.3 EOO00120.1 - 0.16 11.0 7.0 0.04 12.9 1.1 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Phage_GP20 PF06810.6 EOO00120.1 - 0.17 11.2 4.1 0.18 11.2 1.6 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 CENP-Q PF13094.1 EOO00120.1 - 0.18 11.8 2.4 0.56 10.2 0.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WXG100 PF06013.7 EOO00120.1 - 0.2 11.6 4.9 4.5 7.3 0.7 3.5 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF972 PF06156.8 EOO00120.1 - 0.21 11.9 0.9 3.3 8.0 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1515 PF07439.6 EOO00120.1 - 0.22 11.3 7.4 1.1 9.0 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Hemagglutinin PF00509.13 EOO00120.1 - 0.22 9.6 2.1 0.32 9.0 1.4 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF4446 PF14584.1 EOO00120.1 - 0.27 11.0 1.8 0.75 9.6 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF812 PF05667.6 EOO00120.1 - 0.28 9.6 4.4 0.93 7.9 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.7 EOO00120.1 - 0.33 10.7 6.2 1.5 8.6 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4094 PF13334.1 EOO00120.1 - 0.5 10.7 4.0 1.8 8.9 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Filo_VP35 PF02097.10 EOO00120.1 - 2.7 7.1 8.1 0.31 10.1 0.2 2.1 1 1 0 2 2 2 0 Filoviridae VP35 DUF3359 PF11839.3 EOO00120.1 - 2.9 8.2 9.4 7.3 7.0 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) Zein-binding PF04576.10 EOO00120.1 - 3.7 7.7 6.8 1.4 9.1 0.1 3.0 2 1 1 3 3 2 0 Zein-binding Abhydrolase_4 PF08386.5 EOO00121.1 - 7.3e-14 51.5 0.0 1.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EOO00121.1 - 7.2e-11 42.0 0.1 0.00012 21.6 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO00121.1 - 5.9e-09 36.1 1.9 8.5e-08 32.3 1.3 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pmp3 PF01679.12 EOO00122.1 - 1.8e-19 69.1 7.7 2.3e-19 68.7 5.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MFS_1 PF07690.11 EOO00123.1 - 1.6e-13 50.0 48.2 1e-06 27.7 7.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2107 PF09880.4 EOO00123.1 - 0.0025 17.6 1.9 0.0061 16.4 0.1 2.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2107) IPK PF03770.11 EOO00124.1 - 6.5e-54 182.5 0.0 8.1e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Peptidase_S66 PF02016.10 EOO00125.1 - 6.5e-55 186.0 0.0 7.5e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 LD-carboxypeptidase p450 PF00067.17 EOO00126.1 - 3.4e-39 134.6 0.0 5.5e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 EOO00127.1 - 1.1e-37 129.7 1.5 1.8e-37 129.0 1.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EOO00127.1 - 1.6e-13 51.0 0.0 3.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF3378 PF11858.3 EOO00127.1 - 0.033 14.2 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) NmrA PF05368.8 EOO00128.1 - 1.4e-32 112.8 0.0 2.5e-32 111.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO00128.1 - 6.2e-07 29.5 0.2 8.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EOO00128.1 - 0.00017 21.5 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EOO00128.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO00128.1 - 0.0086 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EOO00128.1 - 0.0092 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DAO PF01266.19 EOO00129.1 - 1.4e-22 80.1 0.0 1.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO00129.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TauD PF02668.11 EOO00130.1 - 2.8e-11 43.5 0.0 6.6e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_11 PF08241.7 EOO00131.1 - 5.8e-05 23.4 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00131.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00131.1 - 0.022 15.2 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EOO00131.1 - 0.031 14.2 0.0 0.11 12.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 EOO00132.1 - 7.5e-55 186.2 0.0 9.2e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.7 EOO00133.1 - 2.2e-12 46.9 0.1 8.2e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EOO00133.1 - 0.0047 16.8 0.7 0.039 13.9 0.1 2.7 2 0 0 2 2 2 1 NHL repeat SBBP PF06739.6 EOO00133.1 - 0.015 15.0 0.1 0.054 13.2 0.0 2.0 1 0 0 1 1 1 0 Beta-propeller repeat Bac_rhodopsin PF01036.13 EOO00134.1 - 3.1e-32 111.6 21.5 4e-32 111.3 14.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GMC_oxred_N PF00732.14 EOO00135.1 - 2e-60 204.4 0.1 2.6e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO00135.1 - 1.7e-30 106.1 0.0 5e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EOO00135.1 - 2.3e-05 23.4 0.0 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EOO00135.1 - 3.5e-05 22.8 0.1 6.5e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EOO00135.1 - 4e-05 23.5 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO00135.1 - 0.0001 22.2 0.1 0.00031 20.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO00135.1 - 0.00018 20.5 0.0 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO00135.1 - 0.0012 17.4 0.1 0.0019 16.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EOO00135.1 - 0.014 14.5 0.1 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EOO00135.1 - 0.021 14.8 0.1 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO00135.1 - 0.18 11.5 0.6 0.81 9.4 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding DUF802 PF05650.6 EOO00136.1 - 0.13 12.4 3.7 0.48 10.5 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF802) adh_short PF00106.20 EOO00137.1 - 1.7e-17 63.8 0.6 2.3e-17 63.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00137.1 - 3.9e-08 33.1 0.1 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO00137.1 - 5e-08 32.9 0.0 7.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO00137.1 - 0.0028 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EOO00137.1 - 0.0092 16.0 0.5 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EOO00137.1 - 0.016 14.8 2.4 0.032 13.9 1.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EOO00137.1 - 0.017 14.0 0.3 0.022 13.6 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EOO00137.1 - 0.24 11.1 5.0 0.085 12.6 1.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Arb1 PF09692.5 EOO00138.1 - 3.8e-86 289.4 3.8 4.8e-85 285.8 2.6 2.1 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Methyltransf_23 PF13489.1 EOO00140.1 - 3.5e-06 26.8 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO00140.1 - 0.00023 21.4 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00140.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EOO00140.1 - 0.041 14.3 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00140.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.8 EOO00141.1 - 8e-48 163.0 20.1 5.6e-24 84.2 4.6 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EOO00141.1 - 3.4e-28 98.3 35.1 3.4e-28 98.3 24.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00141.1 - 4.7e-10 38.6 6.7 4.7e-10 38.6 4.6 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1446 PF07287.6 EOO00142.1 - 4.1e-119 397.2 0.6 5e-119 396.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 EOO00142.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 LytB protein ComA PF02679.10 EOO00142.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) YqgF PF14639.1 EOO00142.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Alpha_L_fucos PF01120.12 EOO00144.1 - 2e-83 280.1 7.0 2.7e-83 279.7 4.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EOO00144.1 - 0.0057 16.6 0.1 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 CARDB PF07705.6 EOO00144.1 - 0.068 13.2 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 CARDB Sugar_tr PF00083.19 EOO00145.1 - 9.5e-05 21.1 1.1 0.00011 20.9 0.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter NAD_binding_10 PF13460.1 EOO00146.1 - 3e-08 33.9 0.1 5.3e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO00146.1 - 6.9e-08 32.0 0.1 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EOO00146.1 - 0.037 13.0 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 EOO00146.1 - 0.14 12.7 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold WD40 PF00400.27 EOO00147.1 - 4.9e-33 111.8 2.8 4.4e-09 35.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Zn_Tnp_IS1595 PF12760.2 EOO00147.1 - 0.0074 16.0 3.0 0.014 15.1 2.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain IKI3 PF04762.7 EOO00147.1 - 0.0096 13.7 0.0 2.1 6.0 0.0 2.1 1 1 1 2 2 2 2 IKI3 family Nup160 PF11715.3 EOO00147.1 - 0.078 11.1 2.6 3.1 5.7 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TF_Zn_Ribbon PF08271.7 EOO00147.1 - 0.13 11.6 0.3 0.33 10.2 0.1 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.1 EOO00147.1 - 0.64 9.7 2.9 1.9 8.2 2.0 1.7 1 0 0 1 1 1 0 Nudix N-terminal Sugar_tr PF00083.19 EOO00148.1 - 3.4e-58 197.3 17.5 5e-51 173.6 5.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00148.1 - 5.7e-24 84.4 40.6 1.6e-14 53.3 14.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.26 EOO00149.1 - 3.5e-10 39.5 0.0 9.7e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RXT2_N PF08595.6 EOO00149.1 - 0.38 10.5 5.7 1.6 8.5 4.6 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3295 PF11702.3 EOO00149.1 - 1.3 7.8 9.0 1.6 7.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2457 PF10446.4 EOO00149.1 - 3 6.4 18.3 3.5 6.2 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EOO00149.1 - 4.7 6.3 10.3 6.4 5.9 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EOO00149.1 - 7.4 6.1 8.8 11 5.6 6.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.27 EOO00151.1 - 1e-24 85.4 7.5 1.3e-09 37.5 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EOO00151.1 - 2.7e-17 62.4 0.0 6.9e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_hydro_26 PF02156.10 EOO00154.1 - 7.2e-10 38.8 4.8 1e-09 38.3 2.2 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 Cellulase PF00150.13 EOO00154.1 - 0.0002 20.6 1.2 0.0002 20.6 0.8 1.8 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UDPG_MGDP_dh PF00984.14 EOO00155.1 - 1.6e-27 95.5 0.0 3.5e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EOO00155.1 - 7.7e-24 83.8 0.1 6.4e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.9 EOO00155.1 - 2.1e-22 79.4 0.0 6.4e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EOO00155.1 - 0.0041 16.8 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glycos_transf_2 PF00535.21 EOO00156.1 - 1.1e-20 73.9 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EOO00156.1 - 8.4e-20 71.5 0.1 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EOO00156.1 - 7e-12 45.4 2.5 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EOO00156.1 - 4.4e-11 42.3 0.0 7.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EOO00156.1 - 0.0092 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AhpC-TSA PF00578.16 EOO00157.1 - 1.6e-39 134.3 0.0 2.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EOO00157.1 - 5.9e-14 51.8 0.0 8.4e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EOO00157.1 - 7.2e-12 44.7 0.0 1.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Sugar_tr PF00083.19 EOO00158.1 - 1.5e-113 379.7 25.3 2e-69 234.3 3.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00158.1 - 5.4e-17 61.5 30.5 5.4e-17 61.5 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.1 EOO00158.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Thioredoxin PF00085.15 EOO00159.1 - 1.9e-21 75.7 0.0 3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EOO00159.1 - 2.3e-05 24.5 0.1 0.00029 21.0 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EOO00159.1 - 3e-05 24.0 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EOO00159.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 EOO00159.1 - 0.039 13.6 0.1 0.083 12.5 0.1 1.6 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 EOO00159.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EOO00159.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF1034 PF06280.7 EOO00161.1 - 2.8e-15 56.7 0.7 8.6e-15 55.1 0.0 2.1 3 0 0 3 3 3 1 Fn3-like domain (DUF1034) Peptidase_S8 PF00082.17 EOO00161.1 - 3.3e-06 26.4 1.2 6.5e-06 25.4 0.1 1.9 2 0 0 2 2 2 1 Subtilase family DAO PF01266.19 EOO00162.1 - 2.3e-46 158.3 0.9 2.7e-46 158.1 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO00162.1 - 0.00063 19.6 1.3 0.061 13.1 0.9 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO00162.1 - 0.028 13.4 0.1 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HpcH_HpaI PF03328.9 EOO00163.1 - 5.3e-15 54.8 0.1 6.1e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EOO00163.1 - 0.028 13.0 0.1 0.038 12.6 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain UDPG_MGDP_dh_N PF03721.9 EOO00164.1 - 5.6e-48 162.7 0.0 3.5e-30 104.7 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EOO00164.1 - 1.7e-31 108.3 0.0 3.3e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EOO00164.1 - 5.5e-23 81.1 0.0 1.7e-18 66.7 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EOO00164.1 - 0.0082 15.8 0.6 1.1 8.9 0.6 3.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EOO00164.1 - 0.026 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF848 PF05852.6 EOO00165.1 - 0.038 13.8 2.4 0.062 13.1 1.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.3 EOO00165.1 - 0.066 12.9 6.8 0.29 10.8 4.5 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 EOO00165.1 - 0.17 9.5 9.6 0.34 8.5 6.7 1.4 1 1 0 1 1 1 0 Myosin tail MRP-S31 PF15433.1 EOO00165.1 - 0.28 10.5 4.3 0.39 10.0 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TPR_MLP1_2 PF07926.7 EOO00165.1 - 2.1 8.1 10.6 5 6.8 7.4 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 EOO00165.1 - 2.4 6.3 7.1 3.1 5.9 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2968 PF11180.3 EOO00165.1 - 4.6 6.5 12.0 4.4 6.6 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Activator-TraM PF11657.3 EOO00165.1 - 7.4 6.0 12.9 7.4 6.0 1.9 3.0 2 1 1 3 3 3 0 Transcriptional activator TraM GYF PF02213.11 EOO00166.1 - 3.5e-18 64.9 0.1 6.5e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 GYF domain BTV_NS2 PF04514.7 EOO00166.1 - 0.1 11.4 1.0 0.22 10.3 0.7 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Glyco_hydro_cc PF11790.3 EOO00167.1 - 1.7e-65 220.8 2.1 1.9e-65 220.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_76 PF03663.9 EOO00168.1 - 2.8e-55 188.2 3.9 3.3e-55 187.9 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EOO00168.1 - 0.0023 16.3 0.3 0.23 9.6 0.2 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 EOO00168.1 - 0.0051 15.9 1.1 1.4 7.8 0.0 3.1 2 2 0 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EOO00168.1 - 0.023 13.9 0.0 0.5 9.6 0.0 2.7 2 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Cutinase PF01083.17 EOO00170.1 - 2.7e-44 151.0 0.4 3.4e-44 150.6 0.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EOO00170.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EOO00170.1 - 0.05 13.3 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 EOO00170.1 - 0.08 12.1 0.2 0.47 9.5 0.1 2.0 2 0 0 2 2 2 0 Secretory lipase Methyltransf_18 PF12847.2 EOO00171.1 - 2.4e-14 53.8 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO00171.1 - 5.8e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EOO00171.1 - 1.7e-06 27.7 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EOO00171.1 - 7.3e-06 26.3 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EOO00171.1 - 9.3e-06 26.4 0.0 2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00171.1 - 9.3e-06 26.0 0.0 3.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EOO00171.1 - 0.00014 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EOO00171.1 - 0.00016 21.9 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO00171.1 - 0.00035 20.6 0.1 0.00062 19.7 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00171.1 - 0.00078 19.0 0.1 0.001 18.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EOO00171.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.14 EOO00171.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EOO00171.1 - 0.0033 16.5 0.0 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EOO00171.1 - 0.0042 16.4 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EOO00171.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EOO00171.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 EOO00171.1 - 0.081 12.3 0.0 0.27 10.6 0.0 1.8 2 1 0 2 2 2 0 Nodulation protein S (NodS) Fibrillarin PF01269.12 EOO00171.1 - 0.089 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Sulfate_transp PF00916.15 EOO00173.1 - 6.3e-52 176.3 4.2 6.3e-52 176.3 2.9 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EOO00173.1 - 2.4e-27 94.4 3.1 7.1e-27 92.9 2.2 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EOO00173.1 - 6.6e-17 61.0 0.0 1.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EOO00173.1 - 0.0077 16.2 0.0 0.025 14.6 0.0 2.0 1 1 0 1 1 1 1 STAS domain CTP_transf_1 PF01148.15 EOO00174.1 - 1.7e-80 270.3 28.6 2.1e-80 270.1 19.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 EOO00175.1 - 9.8e-71 237.8 0.1 1.4e-70 237.2 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EOO00175.1 - 1.8e-39 133.9 0.2 4.4e-39 132.7 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EOO00175.1 - 0.074 12.7 0.1 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.1 EOO00176.1 - 1.1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO00176.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EOO00176.1 - 0.004 16.2 0.1 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EOO00176.1 - 0.0068 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 EOO00176.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EOO00176.1 - 0.082 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EOO00176.1 - 0.085 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EOO00176.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 EOO00176.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EOO00176.1 - 0.12 11.2 0.1 0.22 10.3 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 EOO00176.1 - 0.13 12.7 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GTP_cyclohydroI PF01227.17 EOO00177.1 - 1.9e-73 245.5 0.2 2.5e-73 245.1 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EOO00177.1 - 0.00097 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein MFS_1 PF07690.11 EOO00178.1 - 2.8e-38 131.5 31.2 2.8e-38 131.5 21.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2464 PF10240.4 EOO00179.1 - 0.13 11.5 0.1 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) GST_C_2 PF13410.1 EOO00180.1 - 0.00068 19.4 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EOO00180.1 - 0.012 16.1 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RED_N PF07808.8 EOO00181.1 - 0.36 10.0 1.7 0.62 9.2 1.1 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Peptidase_M20 PF01546.23 EOO00182.1 - 2.2e-17 63.2 0.0 2.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EOO00182.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain UPF0150 PF03681.10 EOO00182.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Peptidase_M28 PF04389.12 EOO00182.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 AAA PF00004.24 EOO00183.1 - 5.3e-15 55.7 0.0 9.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO00183.1 - 3.5e-05 23.9 0.3 0.0036 17.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO00183.1 - 0.00043 20.3 0.5 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EOO00183.1 - 0.0046 16.6 0.2 0.017 14.8 0.2 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EOO00183.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EOO00183.1 - 0.064 13.1 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain UvdE PF03851.9 EOO00184.1 - 3.6e-100 334.5 0.0 4.4e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE adh_short PF00106.20 EOO00185.1 - 9.2e-18 64.7 0.0 3.3e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00185.1 - 1.1e-07 31.6 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO00185.1 - 8.1e-06 25.4 0.0 9.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EOO00185.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EOO00185.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EOO00185.1 - 0.092 11.7 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase tRNA-synt_1c PF00749.16 EOO00186.1 - 6.6e-97 323.9 0.1 1.2e-96 323.0 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EOO00186.1 - 1.5e-39 135.4 0.1 2.4e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EOO00186.1 - 0.0028 16.8 0.2 0.008 15.3 0.0 1.6 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain Sterol_MT_C PF08498.5 EOO00187.1 - 2.6e-28 97.7 0.5 3.7e-28 97.2 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EOO00187.1 - 1.6e-22 79.8 0.0 2.4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00187.1 - 9.3e-18 64.2 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO00187.1 - 8.8e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO00187.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00187.1 - 2.9e-13 50.1 0.0 1.1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO00187.1 - 9.4e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO00187.1 - 5e-12 45.4 0.0 1e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EOO00187.1 - 9.4e-11 41.7 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EOO00187.1 - 6.4e-09 35.2 0.0 8.5e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 EOO00187.1 - 1.5e-05 24.6 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EOO00187.1 - 0.00046 19.6 0.0 0.00076 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EOO00187.1 - 0.00092 18.4 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EOO00187.1 - 0.0016 18.0 0.0 0.0028 17.3 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 EOO00187.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 EOO00187.1 - 0.033 13.7 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EOO00187.1 - 0.053 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EOO00187.1 - 0.062 12.9 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EOO00187.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SGL PF08450.7 EOO00188.1 - 1.3e-11 44.3 0.1 3.2e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region MFS_1 PF07690.11 EOO00189.1 - 6.3e-23 81.0 33.5 6.3e-23 81.0 23.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EOO00189.1 - 0.00077 17.6 1.8 0.0037 15.3 0.0 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EOO00189.1 - 0.016 13.6 24.9 0.0036 15.7 4.4 2.4 1 1 0 2 2 2 0 MFS/sugar transport protein PdxA PF04166.7 EOO00190.1 - 1.6e-23 83.4 0.0 2.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF1205 PF06722.7 EOO00190.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) AMP-binding PF00501.23 EOO00191.1 - 1.9e-14 52.9 0.1 1.3e-07 30.3 0.0 2.4 2 1 1 3 3 3 2 AMP-binding enzyme AMP-binding_C PF13193.1 EOO00191.1 - 8.7e-07 29.8 0.0 2.8e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GST_N PF02798.15 EOO00192.1 - 9e-09 35.3 0.0 9.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EOO00192.1 - 2.9e-07 30.6 0.0 3.4e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EOO00192.1 - 7.8e-07 29.0 0.0 9.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.16 EOO00193.1 - 2.6e-68 230.6 0.0 3e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EOO00193.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_S9 PF00326.16 EOO00194.1 - 8.7e-33 113.3 0.0 1.3e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 EOO00194.1 - 1.4e-17 62.9 5.7 1.2e-06 28.0 0.1 5.7 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 EOO00194.1 - 4.1e-14 52.5 0.1 1.6e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO00194.1 - 3.6e-13 49.9 0.1 6.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DPPIV_N PF00930.16 EOO00194.1 - 7.5e-06 24.7 0.0 0.031 12.8 0.0 3.5 2 2 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DLH PF01738.13 EOO00194.1 - 1.7e-05 24.2 0.0 0.00042 19.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EOO00194.1 - 2.8e-05 23.6 0.0 0.056 12.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EOO00194.1 - 0.00079 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 EOO00194.1 - 0.0045 16.5 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 EOO00194.1 - 0.023 13.9 0.9 2 7.5 0.6 2.2 2 0 0 2 2 2 0 Secretory lipase Sulfate_transp PF00916.15 EOO00195.1 - 3.1e-16 59.2 0.0 4.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EOO00195.1 - 1.5e-10 40.5 0.0 2.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EOO00195.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 STAS domain IPP-2 PF04979.9 EOO00196.1 - 1.2e-10 41.6 8.3 2.2e-05 24.6 1.1 2.7 2 1 1 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) adh_short PF00106.20 EOO00197.1 - 1.1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Opi1 PF08618.5 EOO00198.1 - 9.4e-57 192.8 0.9 2.6e-42 145.2 0.0 2.0 1 1 1 2 2 2 2 Transcription factor Opi1 Pyr_redox_2 PF07992.9 EOO00199.1 - 7.2e-26 91.3 5.5 8.4e-25 87.8 3.8 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EOO00199.1 - 1.9e-23 82.6 0.0 3.2e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EOO00199.1 - 4.9e-21 74.9 1.7 1e-20 73.9 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO00199.1 - 4.8e-08 32.3 1.1 0.067 12.0 0.0 3.3 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO00199.1 - 8e-08 32.5 0.1 3.7e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO00199.1 - 2.2e-06 27.5 0.1 0.037 14.0 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EOO00199.1 - 4e-05 22.2 0.3 0.33 9.3 0.1 3.3 2 1 1 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EOO00199.1 - 0.00024 20.7 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EOO00199.1 - 0.00044 20.2 0.3 0.029 14.3 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 EOO00199.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EOO00199.1 - 0.0037 16.1 0.5 2.1 7.1 0.0 3.4 4 0 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.1 EOO00199.1 - 0.0083 15.0 0.0 0.43 9.4 0.0 2.6 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EOO00199.1 - 0.011 15.4 0.1 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EOO00199.1 - 0.014 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.7 EOO00199.1 - 0.037 12.9 0.0 3.5 6.4 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EOO00199.1 - 0.057 12.2 0.3 4.7 5.9 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EOO00199.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIOX_N PF14226.1 EOO00200.1 - 2.7e-12 47.2 0.0 9.5e-11 42.2 0.0 2.6 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO00200.1 - 5e-08 33.1 0.0 8.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EOO00201.1 - 2.1e-40 138.5 46.7 2.1e-40 138.5 32.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO00201.1 - 2.6e-15 55.6 12.5 3.8e-15 55.1 8.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0233 PF06781.7 EOO00201.1 - 0.58 9.8 0.0 0.58 9.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) SET PF00856.23 EOO00202.1 - 4.5e-13 49.8 0.0 6e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 SET domain FAD_binding_3 PF01494.14 EOO00203.1 - 7.4e-77 258.7 0.0 9.7e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EOO00203.1 - 2e-18 66.5 0.0 3.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 EOO00203.1 - 6.2e-06 26.4 0.0 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO00203.1 - 1.9e-05 24.6 0.1 5.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO00203.1 - 2.5e-05 23.3 0.0 0.00023 20.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EOO00203.1 - 0.00029 21.1 0.0 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO00203.1 - 0.00044 19.2 0.1 0.0031 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EOO00203.1 - 0.00054 18.5 0.0 0.0012 17.4 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EOO00203.1 - 0.00065 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EOO00203.1 - 0.00071 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EOO00203.1 - 0.0017 17.3 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EOO00203.1 - 0.011 14.8 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 EOO00203.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EOO00203.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EOO00203.1 - 0.049 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EOO00203.1 - 0.098 11.8 0.0 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.16 EOO00204.1 - 1.1e-19 70.2 0.0 2.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EOO00204.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Transketolase_N PF00456.16 EOO00205.1 - 1.3e-122 408.8 0.0 1.8e-122 408.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain FAA_hydrolase PF01557.13 EOO00205.1 - 3.6e-55 186.7 0.0 7.7e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Transket_pyr PF02779.19 EOO00205.1 - 9.4e-23 80.6 0.0 1.4e-21 76.7 0.0 2.3 1 1 1 2 2 2 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EOO00205.1 - 1.2e-08 34.2 0.0 3.1e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EOO00205.1 - 1.8e-08 34.3 0.0 4.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EOO00205.1 - 2.4e-05 23.2 0.0 4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component PepSY_2 PF13670.1 EOO00205.1 - 0.021 14.7 0.1 0.066 13.1 0.1 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ApoB100_C PF12491.3 EOO00205.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal p450 PF00067.17 EOO00206.1 - 4.1e-45 154.1 0.0 3e-44 151.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FmrO PF07091.6 EOO00206.1 - 0.095 11.6 0.6 1.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) SBP_bac_3 PF00497.15 EOO00207.1 - 0.00024 20.4 0.0 0.00072 18.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 EOO00207.1 - 0.011 15.3 0.0 0.21 11.1 0.0 2.4 1 1 0 1 1 1 0 NMT1/THI5 like DUF3834 PF12916.2 EOO00207.1 - 0.061 12.3 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) SRP54 PF00448.17 EOO00208.1 - 2.4e-76 255.5 2.4 5.2e-76 254.4 0.6 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EOO00208.1 - 1.9e-25 89.1 6.6 1.9e-25 89.1 4.6 3.9 3 1 2 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 EOO00208.1 - 3.2e-16 59.1 0.2 7.1e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EOO00208.1 - 6e-09 35.5 0.1 1.5e-08 34.2 0.0 1.7 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EOO00208.1 - 3.2e-08 33.5 0.1 1.2e-07 31.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EOO00208.1 - 1.2e-05 25.0 0.0 3.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EOO00208.1 - 2.8e-05 24.9 0.0 6.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EOO00208.1 - 7.4e-05 22.2 0.1 0.00026 20.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EOO00208.1 - 0.00098 19.0 0.0 0.4 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EOO00208.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EOO00208.1 - 0.002 18.1 0.2 0.0073 16.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 EOO00208.1 - 0.0023 17.2 0.9 2.5 7.2 0.6 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EOO00208.1 - 0.0031 16.8 0.2 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.1 EOO00208.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EOO00208.1 - 0.0038 16.0 3.6 0.0048 15.7 0.7 2.3 2 1 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EOO00208.1 - 0.0044 16.1 0.0 0.0044 16.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.12 EOO00208.1 - 0.0058 16.2 0.2 0.039 13.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EOO00208.1 - 0.0076 14.9 0.0 0.019 13.5 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EOO00208.1 - 0.0081 15.6 0.3 0.022 14.1 0.2 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EOO00208.1 - 0.0089 16.3 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EOO00208.1 - 0.017 15.0 0.2 0.044 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EOO00208.1 - 0.02 14.8 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase 6PF2K PF01591.13 EOO00208.1 - 0.034 13.2 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.1 EOO00208.1 - 0.063 13.0 0.1 0.28 10.9 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EOO00208.1 - 0.064 13.4 0.2 0.25 11.5 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 EOO00208.1 - 0.1 11.8 0.1 0.33 10.1 0.0 1.8 2 0 0 2 2 1 0 ADP-ribosylation factor family Torsin PF06309.6 EOO00208.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 1 0 1 1 1 0 Torsin Fungal_trans PF04082.13 EOO00209.1 - 4.9e-21 74.7 0.0 7.8e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EOO00210.1 - 1.2e-33 116.3 22.8 1.2e-33 116.3 15.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EOO00210.1 - 0.00031 20.4 5.7 0.00044 19.9 0.1 3.2 4 0 0 4 4 4 1 MFS_1 like family Peptidase_S15 PF02129.13 EOO00212.1 - 5e-41 140.9 0.3 6.3e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EOO00212.1 - 1.8e-05 24.5 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO00212.1 - 0.00011 22.1 0.2 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PepX_C PF08530.5 EOO00212.1 - 0.03 14.2 0.3 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.16 EOO00212.1 - 0.08 12.1 0.3 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydantoinase_B PF02538.9 EOO00213.1 - 4.2e-151 503.7 0.0 6.1e-151 503.2 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO00213.1 - 1.1e-85 287.2 0.0 3.1e-85 285.8 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO00213.1 - 1.4e-48 164.7 1.9 7.1e-47 159.1 0.1 2.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EOO00213.1 - 0.056 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature PARP PF00644.15 EOO00214.1 - 3.8e-59 199.5 0.0 1e-58 198.1 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EOO00214.1 - 1e-40 138.5 0.2 1.5e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EOO00214.1 - 1.4e-22 79.4 0.2 1.4e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 WGR domain BRCT PF00533.21 EOO00214.1 - 3.3e-12 46.3 0.0 7.8e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EOO00214.1 - 2e-09 37.1 0.0 5.1e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Glyco_hydro_76 PF03663.9 EOO00215.1 - 1.7e-141 471.9 18.0 2.1e-141 471.6 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Mem_trans PF03547.13 EOO00216.1 - 2e-06 26.3 0.1 2.1e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 Membrane transport protein DUF4112 PF13430.1 EOO00216.1 - 0.033 14.1 0.2 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Fungal_trans_2 PF11951.3 EOO00217.1 - 3.5e-17 62.0 1.9 6e-17 61.3 1.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2834 PF11196.3 EOO00218.1 - 0.61 10.2 18.4 0.34 11.0 2.3 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF2834) Ribosomal_L1 PF00687.16 EOO00219.1 - 2.4e-23 82.6 0.1 2.9e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DIOX_N PF14226.1 EOO00220.1 - 1e-29 103.4 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO00220.1 - 1.3e-24 86.3 0.0 2.8e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily F-box PF00646.28 EOO00221.1 - 0.00062 19.3 0.3 0.0016 18.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EOO00221.1 - 0.012 15.2 2.0 0.024 14.3 0.3 2.3 2 0 0 2 2 2 0 F-box-like E1-E2_ATPase PF00122.15 EOO00222.1 - 2.6e-41 141.1 1.6 4.9e-41 140.2 1.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EOO00222.1 - 2.7e-31 109.6 0.1 3.1e-30 106.1 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EOO00222.1 - 7.2e-20 71.9 0.0 2.3e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO00222.1 - 1.1e-16 60.5 0.0 2.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 EOO00222.1 - 9.7e-15 54.5 2.8 1e-14 54.5 0.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EOO00222.1 - 0.00017 21.2 0.4 0.0012 18.4 0.2 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 EOO00222.1 - 0.089 13.1 1.0 0.28 11.5 0.7 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Hydantoinase_B PF02538.9 EOO00223.1 - 5.1e-186 618.9 0.0 6.4e-186 618.6 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Proteasome_A_N PF10584.4 EOO00223.1 - 0.015 14.6 0.2 0.035 13.4 0.2 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Phage_Mu_Gp45 PF06890.7 EOO00223.1 - 0.077 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein 2OG-FeII_Oxy PF03171.15 EOO00224.1 - 5.1e-17 61.9 0.0 8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EOO00225.1 - 7.4e-13 47.9 17.1 1e-12 47.4 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EOO00225.1 - 0.16 12.1 7.7 3 7.9 0.5 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EOO00225.1 - 0.57 9.5 3.5 1.2 8.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 EOO00226.1 - 0.027 13.0 0.3 0.034 12.7 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EOO00227.1 - 2.7e-30 105.8 0.2 3.3e-30 105.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO00227.1 - 1.1e-19 70.9 3.1 1.5e-19 70.5 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00227.1 - 2.9e-10 40.1 0.6 4.9e-10 39.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Glyco_transf_28 PF03033.15 EOO00227.1 - 0.031 14.0 0.0 0.082 12.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ETX_MTX2 PF03318.8 EOO00227.1 - 0.12 11.9 0.2 9.3 5.7 0.1 2.0 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 SAM_decarbox PF01536.11 EOO00228.1 - 1.2e-85 287.1 0.0 6.4e-82 274.8 0.0 3.8 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Cyt-b5 PF00173.23 EOO00229.1 - 3.1e-16 58.9 0.0 2e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EOO00229.1 - 0.00084 18.8 3.0 0.0013 18.2 2.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Ribosomal_L27 PF01016.14 EOO00230.1 - 1.1e-23 82.7 0.0 2.4e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein Gti1_Pac2 PF09729.4 EOO00230.1 - 0.11 12.3 2.3 0.16 11.8 1.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF1127 PF06568.6 EOO00230.1 - 0.34 10.3 3.0 0.68 9.3 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DLH PF01738.13 EOO00231.1 - 6.1e-13 48.5 0.0 6.8e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EOO00231.1 - 0.00076 19.2 0.0 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO00231.1 - 0.017 15.0 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00231.1 - 0.017 14.6 0.1 0.027 14.0 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold ISN1 PF06437.6 EOO00231.1 - 0.13 10.9 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase TauD PF02668.11 EOO00232.1 - 9.8e-50 169.6 0.0 1.1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fer2 PF00111.22 EOO00234.1 - 4.4e-13 48.7 0.8 6.1e-13 48.3 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PAP2 PF01569.16 EOO00235.1 - 3.4e-21 75.2 2.5 3.4e-21 75.2 1.7 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF983 PF06170.7 EOO00235.1 - 2.5 8.2 5.2 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Rrp15p PF07890.7 EOO00236.1 - 4.6e-35 120.5 7.0 4.6e-35 120.5 4.9 1.8 2 0 0 2 2 2 1 Rrp15p CAF1A PF12253.3 EOO00236.1 - 3.2 7.9 15.2 0.53 10.4 5.1 2.3 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A Adap_comp_sub PF00928.16 EOO00237.1 - 5e-90 301.1 0.0 6.6e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EOO00237.1 - 1.2e-08 34.8 0.2 2e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 2-Hacid_dh_C PF02826.14 EOO00238.1 - 2.9e-35 121.0 0.0 4.9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EOO00238.1 - 2.2e-10 40.1 0.0 2.5e-09 36.6 0.0 2.5 3 1 1 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EOO00238.1 - 9.8e-08 31.9 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Lyase_1 PF00206.15 EOO00239.1 - 9.4e-26 90.7 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Lyase FAA_hydrolase PF01557.13 EOO00240.1 - 5.9e-51 172.9 0.0 7.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NADH5_C PF06455.6 EOO00241.1 - 0.037 13.3 0.1 0.037 13.3 0.1 2.1 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus MFS_1 PF07690.11 EOO00242.1 - 8.7e-27 93.7 40.8 8.7e-27 93.7 28.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.3 EOO00242.1 - 0.018 14.6 3.1 0.018 14.6 2.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4131 PF13567.1 EOO00242.1 - 0.74 9.1 7.9 2.3 7.5 1.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) NfeD PF01957.13 EOO00242.1 - 2.3 8.3 14.0 1.1 9.4 0.9 3.5 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding SnoaL PF07366.7 EOO00243.1 - 0.0011 18.4 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EOO00243.1 - 0.003 17.9 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain Methyltransf_24 PF13578.1 EOO00244.1 - 1.7e-14 54.5 0.0 2.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EOO00244.1 - 1.5e-08 33.9 0.0 2.7e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.6 EOO00244.1 - 1.5e-06 27.5 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Methyltransf_18 PF12847.2 EOO00244.1 - 0.00064 20.2 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CNPase PF05881.7 EOO00244.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) CmcI PF04989.7 EOO00244.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Glyco_hydro_6 PF01341.12 EOO00245.1 - 2.8e-90 302.7 0.7 3.2e-90 302.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 COG2 PF06148.6 EOO00246.1 - 1.9e-18 66.6 0.1 7.2e-18 64.7 0.0 2.0 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EOO00246.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Dor1 PF04124.7 EOO00246.1 - 0.089 11.2 0.0 0.18 10.2 0.0 1.5 2 0 0 2 2 2 0 Dor1-like family MFS_1 PF07690.11 EOO00247.1 - 3.7e-14 52.2 20.0 1.9e-13 49.8 14.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3180 PF11377.3 EOO00247.1 - 0.02 14.7 0.6 0.049 13.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Mito_carr PF00153.22 EOO00248.1 - 1.9e-16 59.5 0.1 0.00012 21.7 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Ectatomin PF06457.6 EOO00248.1 - 0.07 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Ectatomin Thymidylate_kin PF02223.12 EOO00249.1 - 8.8e-43 145.8 0.0 2.8e-41 140.9 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EOO00249.1 - 8.8e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EOO00249.1 - 0.0089 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EOO00249.1 - 0.032 13.8 0.0 0.39 10.3 0.0 2.2 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EOO00249.1 - 0.039 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MFS_1 PF07690.11 EOO00250.1 - 7.2e-07 28.2 9.9 0.0015 17.3 0.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EOO00251.1 - 9.8e-32 110.0 30.4 9.8e-32 110.0 21.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EOO00251.1 - 5.5 6.5 9.7 2.1 7.9 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) ParA PF10609.4 EOO00252.1 - 3.6e-36 122.8 0.1 6.4e-36 122.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EOO00252.1 - 5.7e-15 55.2 0.0 1e-14 54.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EOO00252.1 - 7.5e-07 28.4 0.0 1.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EOO00252.1 - 1.5e-05 24.1 0.3 6.3e-05 22.1 0.3 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EOO00252.1 - 0.00012 22.0 0.1 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EOO00252.1 - 0.0012 17.6 0.4 0.002 16.9 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EOO00252.1 - 0.0026 17.2 0.1 0.0048 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EOO00252.1 - 0.015 14.7 0.5 0.023 14.0 0.3 1.5 1 1 0 1 1 1 0 YhjQ protein AAA_26 PF13500.1 EOO00252.1 - 0.033 13.7 0.4 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EOO00252.1 - 0.09 11.9 1.7 0.15 11.2 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EOO00252.1 - 0.098 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Sugar_tr PF00083.19 EOO00253.1 - 8.6e-65 219.0 17.1 1.8e-58 198.2 7.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00253.1 - 3.1e-10 39.2 23.7 1.9e-08 33.4 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO00253.1 - 8.3e-05 21.1 3.7 8.3e-05 21.1 2.5 3.3 2 1 0 2 2 2 1 MFS/sugar transport protein E1-E2_ATPase PF00122.15 EOO00253.1 - 4.1 6.3 6.4 0.6 9.1 1.6 1.7 2 0 0 2 2 2 0 E1-E2 ATPase Aldedh PF00171.17 EOO00254.1 - 1.6e-131 438.8 1.4 1.8e-131 438.6 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EOO00254.1 - 1.9e-07 30.1 0.0 3.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EOO00254.1 - 0.00078 18.7 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Choline_transpo PF04515.7 EOO00255.1 - 6e-104 347.3 17.8 6e-104 347.3 12.4 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter TAFII28 PF04719.9 EOO00257.1 - 2.9e-16 59.0 1.6 3.6e-13 49.1 0.9 3.2 2 1 0 2 2 2 1 hTAFII28-like protein conserved region Dala_Dala_lig_C PF07478.8 EOO00257.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus COesterase PF00135.23 EOO00259.1 - 6.9e-79 265.9 0.0 9.1e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO00259.1 - 6e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO00259.1 - 0.0034 17.1 0.0 0.0075 16.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EOO00259.1 - 0.016 14.4 0.2 0.027 13.7 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family 6PF2K PF01591.13 EOO00260.1 - 4.7e-80 267.8 0.1 6.5e-80 267.3 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EOO00260.1 - 7.9e-32 110.5 0.0 1.7e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EOO00260.1 - 1.9e-10 40.8 0.1 3.4e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EOO00260.1 - 6.1e-05 22.3 0.1 0.0001 21.6 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EOO00260.1 - 0.00014 22.6 1.5 0.0046 17.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain His_Phos_2 PF00328.17 EOO00260.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Peptidase_M43 PF05572.8 EOO00261.1 - 8.6e-19 67.6 1.7 1.5e-18 66.8 1.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EOO00261.1 - 1.6e-07 31.4 1.4 2.5e-07 30.8 0.9 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EOO00261.1 - 5.6e-07 29.7 2.7 1e-06 28.9 1.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EOO00261.1 - 1.2e-06 29.0 0.2 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EOO00261.1 - 0.0004 19.9 4.0 0.0012 18.4 2.7 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EOO00261.1 - 0.0024 16.8 0.1 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.19 EOO00261.1 - 0.0071 16.0 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.6 EOO00261.1 - 0.048 13.4 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M57 PF12388.3 EOO00261.1 - 0.097 11.9 1.1 0.23 10.7 0.8 1.6 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Sugar_tr PF00083.19 EOO00262.1 - 3.1e-81 273.2 20.1 3.5e-81 273.0 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00262.1 - 4.4e-36 124.3 47.0 1.6e-32 112.5 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.24 EOO00263.1 - 4.6e-18 65.6 0.0 8.8e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO00263.1 - 0.0001 22.4 0.1 0.0025 17.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO00263.1 - 0.00018 21.1 0.1 0.00063 19.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EOO00263.1 - 0.0012 18.9 0.1 0.0048 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EOO00263.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EOO00263.1 - 0.0059 17.4 0.0 0.031 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EOO00263.1 - 0.032 14.1 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EOO00263.1 - 0.05 12.7 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EOO00263.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EOO00263.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EOO00263.1 - 0.2 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain 2OG-FeII_Oxy PF03171.15 EOO00264.1 - 7.7e-24 83.8 0.0 3.2e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EOO00264.1 - 2.1e-23 83.0 0.0 3.5e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Tyrosinase PF00264.15 EOO00265.1 - 2e-45 155.6 0.0 2.9e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Epimerase PF01370.16 EOO00266.1 - 5e-14 52.3 0.0 2.3e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO00266.1 - 9.3e-11 42.0 0.0 2.2e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EOO00266.1 - 1.9e-06 26.7 0.0 2.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EOO00266.1 - 1.8e-05 24.1 0.0 7.4e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EOO00266.1 - 0.0004 19.3 0.0 0.0012 17.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EOO00266.1 - 0.018 13.9 0.0 0.37 9.6 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain Bromodomain PF00439.20 EOO00267.1 - 1.6e-36 124.0 0.0 6.6e-21 74.0 0.1 2.7 2 0 0 2 2 2 2 Bromodomain EpsG PF14897.1 EOO00268.1 - 0.08 11.8 3.0 0.12 11.2 2.1 1.3 1 0 0 1 1 1 0 EpsG family RTA1 PF04479.8 EOO00269.1 - 9.4e-49 165.9 4.9 1.3e-48 165.4 3.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 EOO00269.1 - 0.015 14.3 6.4 0.03 13.3 4.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PalH PF08733.5 EOO00269.1 - 0.054 12.3 0.2 0.083 11.7 0.1 1.4 1 1 0 1 1 1 0 PalH/RIM21 Orbi_NS3 PF01616.11 EOO00269.1 - 0.097 11.6 0.1 0.23 10.4 0.0 1.6 1 1 1 2 2 2 0 Orbivirus NS3 DUF2613 PF11021.3 EOO00270.1 - 0.89 9.3 5.6 0.13 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) SNARE PF05739.14 EOO00272.1 - 1.3e-10 40.8 3.8 2.7e-10 39.7 2.6 1.6 1 0 0 1 1 1 1 SNARE domain Snapin_Pallidin PF14712.1 EOO00272.1 - 0.13 12.6 1.9 6.1 7.2 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin PF00804.20 EOO00272.1 - 0.18 12.0 4.8 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Syntaxin Phage_GP20 PF06810.6 EOO00272.1 - 0.28 10.6 4.5 0.2 11.1 0.2 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 CorA PF01544.13 EOO00272.1 - 0.35 9.8 0.0 0.35 9.8 0.0 2.5 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 EOO00273.1 - 5.8e-29 100.9 10.2 6.5e-29 100.7 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00273.1 - 2.9e-06 26.2 4.4 3.5e-06 25.9 3.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 EOO00273.1 - 0.32 10.7 2.2 0.49 10.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DUF373 PF04123.8 EOO00273.1 - 0.35 9.8 2.9 0.42 9.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TPR_12 PF13424.1 EOO00274.1 - 2.1e-13 50.0 15.8 2.9e-06 27.0 0.4 4.6 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 EOO00274.1 - 1.3e-08 34.4 5.4 0.047 13.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EOO00274.1 - 4.4e-07 29.4 2.9 0.00082 18.9 0.5 3.0 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EOO00274.1 - 2.8e-05 24.3 3.4 0.26 12.0 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00274.1 - 0.00057 20.4 2.4 0.1 13.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EOO00274.1 - 0.00062 20.0 3.9 6.2 7.2 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EOO00274.1 - 0.0013 18.5 9.0 0.25 11.3 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EOO00274.1 - 0.22 11.3 4.2 16 5.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EOO00274.1 - 1.5 9.4 5.5 4.7 7.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_42M PF08532.5 EOO00275.1 - 0.00026 20.1 0.0 0.001 18.2 0.0 1.9 2 1 0 2 2 2 1 Beta-galactosidase trimerisation domain DUF2457 PF10446.4 EOO00276.1 - 0.14 10.8 26.1 0.19 10.4 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IFT57 PF10498.4 EOO00276.1 - 1.5 7.4 8.5 1.9 7.1 5.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC45 PF02724.9 EOO00276.1 - 6.4 4.6 12.2 8.4 4.2 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EOO00276.1 - 8.1 4.2 19.7 10 3.9 13.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.3 EOO00276.1 - 8.1 5.3 7.6 9.9 5.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PhyH PF05721.8 EOO00279.1 - 4e-14 53.1 0.0 6.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EOO00279.1 - 3.8e-08 32.2 0.0 0.00033 19.2 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.1 EOO00279.1 - 0.045 14.2 0.1 0.15 12.5 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Utp12 PF04003.7 EOO00280.1 - 6.9e-22 77.4 0.3 1.1e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ELO PF01151.13 EOO00281.1 - 1.4e-50 171.9 11.9 8e-26 90.8 3.4 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family UPF0182 PF03699.8 EOO00281.1 - 0.058 11.3 3.9 0.079 10.8 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MatC_N PF07158.6 EOO00281.1 - 3.2 7.5 5.8 2.7 7.7 2.5 1.8 1 1 1 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Transp_cyt_pur PF02133.10 EOO00282.1 - 4.3e-41 140.8 13.6 5.4e-41 140.5 9.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.17 EOO00284.1 - 4.5e-22 78.2 0.0 5.9e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1628 PF07790.6 EOO00285.1 - 0.011 16.4 0.1 0.031 15.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) CTP_transf_1 PF01148.15 EOO00285.1 - 0.095 12.3 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family TPPK_C PF12555.3 EOO00285.1 - 0.16 11.6 3.9 0.15 11.8 0.9 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal VirB8 PF04335.8 EOO00285.1 - 0.19 11.2 1.1 2.5 7.6 0.2 2.5 3 0 0 3 3 3 0 VirB8 protein GATase_5 PF13507.1 EOO00287.1 - 3.5e-100 334.2 0.0 5.2e-100 333.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EOO00287.1 - 1.3e-38 132.4 0.1 1.1e-20 74.2 0.0 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EOO00287.1 - 3.4e-21 75.2 0.1 1.9e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF3378 PF11858.3 EOO00287.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) Amidase PF01425.16 EOO00288.1 - 1.7e-24 86.4 0.0 1.9e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Amidase p450 PF00067.17 EOO00289.1 - 3.9e-14 52.0 0.0 5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EOO00290.1 - 5.1e-41 140.9 1.5 6.9e-41 140.5 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EOO00290.1 - 0.00011 22.6 0.1 1.8 9.0 0.0 3.7 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EOO00290.1 - 0.00011 21.8 0.2 0.0011 18.5 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EOO00290.1 - 0.0095 15.7 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF377 PF04041.8 EOO00291.1 - 6.8e-06 25.0 0.1 5.2e-05 22.1 0.0 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF377) ADP_ribosyl_GH PF03747.9 EOO00292.1 - 6e-39 134.5 0.7 8.9e-39 133.9 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sugar_tr PF00083.19 EOO00293.1 - 4.2e-118 394.7 33.5 4.8e-118 394.5 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00293.1 - 1.1e-19 70.4 60.8 4.9e-17 61.6 22.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO00293.1 - 5.3e-07 28.3 33.2 9e-07 27.6 8.4 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 EOO00293.1 - 0.028 12.6 12.0 0.037 12.2 1.9 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3353 PF11833.3 EOO00294.1 - 0.025 14.0 2.6 0.032 13.7 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Tetraspannin PF00335.15 EOO00294.1 - 0.37 10.0 2.5 0.72 9.0 1.7 1.5 1 0 0 1 1 1 0 Tetraspanin family Pentapeptide_4 PF13599.1 EOO00295.1 - 0.0093 15.7 0.7 0.017 14.9 0.5 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Ribosomal_L28 PF00830.14 EOO00296.1 - 3.7e-21 74.7 1.4 5.5e-21 74.1 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family p450 PF00067.17 EOO00297.1 - 1.7e-65 221.3 0.0 2.2e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAC3_GANP PF03399.11 EOO00297.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GFO_IDH_MocA PF01408.17 EOO00298.1 - 1.9e-17 63.9 0.1 3.1e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EOO00298.1 - 0.0086 16.4 0.1 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EOO00298.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EOO00299.1 - 1.4e-15 57.3 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00299.1 - 2.5e-05 23.9 0.0 0.013 15.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EOO00299.1 - 6.3e-05 23.5 0.0 0.35 11.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.9 EOO00299.1 - 0.0061 15.9 0.0 0.082 12.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EOO00299.1 - 0.013 15.9 0.0 0.52 10.8 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain PPTA PF01239.17 EOO00300.1 - 3.7e-33 111.4 7.5 1.9e-09 36.4 0.4 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3720 PF12517.3 EOO00300.1 - 0.042 14.5 3.4 0.09 13.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF1674 PF07896.7 EOO00302.1 - 7.5e-18 64.4 1.1 1.3e-17 63.7 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) KH_1 PF00013.24 EOO00303.1 - 6.7e-41 137.7 12.4 2e-15 56.1 1.0 3.8 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EOO00303.1 - 3.5e-31 106.2 15.5 4.4e-11 42.1 1.7 4.2 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EOO00303.1 - 4.6e-12 45.3 3.5 0.0068 15.9 0.0 3.5 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 EOO00303.1 - 2.9e-09 36.4 1.7 0.15 11.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EOO00303.1 - 0.0025 17.5 2.9 1 9.2 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain HET PF06985.6 EOO00304.1 - 1.8e-27 96.1 0.6 3.6e-27 95.2 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spherulin4 PF12138.3 EOO00305.1 - 3.8e-40 137.9 0.5 4.4e-40 137.7 0.4 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF829 PF05705.9 EOO00306.1 - 1.1e-37 129.9 0.0 1.4e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Trp_syntA PF00290.15 EOO00307.1 - 5.8e-96 319.9 0.0 1e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EOO00307.1 - 6.8e-45 153.6 0.8 1.1e-44 152.9 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 EOO00307.1 - 0.00054 19.2 0.1 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 PcrB family CLN3 PF02487.12 EOO00308.1 - 5.8e-60 203.1 0.3 8.6e-60 202.6 0.2 1.2 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EOO00308.1 - 0.0041 15.8 8.6 0.0055 15.4 6.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3433 PF11915.3 EOO00309.1 - 2.6e-10 40.2 0.7 5.8e-10 39.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) MFS_1 PF07690.11 EOO00311.1 - 1.4e-10 40.4 28.1 1.4e-10 40.4 19.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EOO00311.1 - 0.00087 18.8 6.0 0.00087 18.8 4.2 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EOO00311.1 - 0.51 8.8 25.4 0.033 12.7 7.7 2.2 1 1 0 2 2 2 0 Sugar (and other) transporter Exo_endo_phos PF03372.18 EOO00312.1 - 9.2e-08 32.3 0.1 1.9e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.24 EOO00313.1 - 2.1e-44 150.9 0.0 1.5e-43 148.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EOO00313.1 - 2.9e-22 77.9 0.1 6.6e-22 76.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EOO00313.1 - 8.4e-22 76.8 0.1 7.2e-21 73.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CH PF00307.26 EOO00313.1 - 0.062 13.3 0.1 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain Daxx PF03344.10 EOO00313.1 - 0.38 9.1 12.7 0.51 8.7 8.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF4349 PF14257.1 EOO00313.1 - 0.69 9.0 8.5 0.25 10.5 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Pox_Ag35 PF03286.9 EOO00313.1 - 4.5 6.7 12.4 7.3 6.0 8.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EOO00313.1 - 5.2 4.8 11.9 7.2 4.3 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.20 EOO00315.1 - 8e-15 55.1 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00315.1 - 5.4e-06 26.1 0.1 8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO00315.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EOO00315.1 - 0.00026 20.7 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EOO00315.1 - 0.091 11.6 0.0 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 EOO00316.1 - 7.1e-79 265.4 21.7 8.3e-79 265.2 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00316.1 - 5e-18 64.9 26.2 5e-18 64.9 18.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4605 PF15378.1 EOO00316.1 - 0.16 11.6 4.3 0.13 11.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) AA_permease_2 PF13520.1 EOO00317.1 - 2.7e-19 69.0 13.7 5.3e-18 64.7 9.5 2.1 1 1 0 1 1 1 1 Amino acid permease DUF418 PF04235.7 EOO00317.1 - 0.085 12.5 8.3 1.9 8.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF418) DUF373 PF04123.8 EOO00317.1 - 0.2 10.6 2.7 0.33 9.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MFS_1 PF07690.11 EOO00318.1 - 2.1e-31 108.9 22.1 3.3e-31 108.2 15.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 EOO00318.1 - 0.49 10.1 6.3 0.045 13.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Microtub_assoc PF07989.6 EOO00319.1 - 0.00097 18.9 6.7 0.0021 17.8 4.7 1.6 1 0 0 1 1 1 1 Microtubule associated Adeno_100 PF02438.11 EOO00319.1 - 0.32 9.1 2.5 0.48 8.5 1.7 1.1 1 0 0 1 1 1 0 Late 100kD protein TEX13 PF15186.1 EOO00319.1 - 1 8.8 5.8 2.4 7.7 4.0 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family ATP_bind_3 PF01171.15 EOO00321.1 - 6.8e-38 129.9 0.0 6.3e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 EOO00321.1 - 0.00011 21.7 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase E1-E2_ATPase PF00122.15 EOO00322.1 - 8.8e-43 145.9 0.5 1.5e-42 145.1 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EOO00322.1 - 6.1e-31 107.3 10.6 6.1e-31 107.3 7.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EOO00322.1 - 3.6e-29 102.7 0.0 1e-27 97.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO00322.1 - 2.7e-17 62.5 0.0 6.8e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EOO00322.1 - 4.3e-15 56.3 0.0 9.7e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO00322.1 - 0.00014 21.5 0.1 0.0022 17.5 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GSDH PF07995.6 EOO00323.1 - 1.4e-05 24.3 0.0 2.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EOO00323.1 - 0.028 13.7 0.1 0.095 12.0 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region GxDLY PF14607.1 EOO00323.1 - 0.076 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type PRKCSH PF07915.8 EOO00324.1 - 6.4e-17 62.1 1.3 6.4e-17 62.1 0.9 2.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Aminotran_1_2 PF00155.16 EOO00325.1 - 1.3e-92 310.5 0.0 2e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TRI12 PF06609.8 EOO00326.1 - 1.3e-27 96.2 12.0 1.6e-27 96.0 8.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EOO00326.1 - 0.0034 16.1 27.3 0.035 12.8 18.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4538 PF15061.1 EOO00326.1 - 2.3 7.6 4.6 2.1 7.7 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Pox_A14 PF05767.7 EOO00326.1 - 4.9 7.1 9.6 0.13 12.1 1.3 2.3 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 PgaD PF13994.1 EOO00327.1 - 0.06 12.8 0.4 2.1 7.8 0.0 2.8 2 0 0 2 2 2 0 PgaD-like protein PspB PF06667.7 EOO00327.1 - 0.066 13.1 0.1 0.94 9.4 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B adh_short PF00106.20 EOO00328.1 - 1.2e-14 54.5 0.1 2.2e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00328.1 - 4.8e-08 32.8 0.1 1.1e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EOO00328.1 - 0.00071 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EOO00328.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EOO00328.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EOO00328.1 - 0.15 11.8 0.5 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Asp_Glu_race PF01177.17 EOO00329.1 - 3.1e-17 63.2 0.1 4.1e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DPBB_1 PF03330.13 EOO00329.1 - 6.1e-05 22.9 0.1 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EOO00329.1 - 0.087 12.5 0.2 0.66 9.6 0.1 2.2 2 0 0 2 2 2 0 Barwin family His_Phos_2 PF00328.17 EOO00330.1 - 0.00019 20.9 0.0 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SBP_bac_10 PF07596.6 EOO00330.1 - 0.0012 18.8 1.4 0.0027 17.7 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1559) HCV_NS5a_1b PF08301.8 EOO00330.1 - 0.017 15.4 0.3 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Hepatitis C virus non-structural 5a domain 1b Sugar_tr PF00083.19 EOO00332.1 - 0.0023 16.5 0.5 0.0025 16.4 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Mpp10 PF04006.7 EOO00333.1 - 2.1e-93 313.7 68.8 4.6e-91 306.0 47.7 2.3 1 1 0 1 1 1 1 Mpp10 protein DUF3164 PF11363.3 EOO00333.1 - 0.0024 17.2 0.2 0.0024 17.2 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) DUF1423 PF07227.6 EOO00333.1 - 2.7 6.5 6.8 3.4 6.2 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1423) MFS_1 PF07690.11 EOO00335.1 - 5.8e-34 117.3 56.7 2.8e-33 115.1 39.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00335.1 - 7.2e-08 31.4 14.8 7.2e-08 31.4 10.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Formyl_trans_N PF00551.14 EOO00337.1 - 1.1e-21 77.2 0.0 4.7e-21 75.1 0.0 2.1 2 1 0 2 2 2 1 Formyl transferase MFS_1 PF07690.11 EOO00341.1 - 1e-46 159.2 24.8 1.2e-46 159.0 17.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00341.1 - 3.6e-18 65.3 21.4 1.5e-17 63.3 14.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EOO00341.1 - 1.6e-05 23.3 2.5 2.5e-05 22.6 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EOO00341.1 - 0.34 8.8 4.1 1 7.3 0.1 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CIAPIN1 PF05093.8 EOO00342.1 - 2.4e-34 117.3 4.2 4e-34 116.6 2.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Aldo_ket_red PF00248.16 EOO00343.1 - 1e-66 224.6 0.1 1.2e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AHH PF14412.1 EOO00343.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH NMO PF03060.10 EOO00344.1 - 7e-42 143.7 10.4 5.6e-41 140.7 7.2 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EOO00344.1 - 1.1e-06 27.7 5.0 9.6e-05 21.4 3.5 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EOO00344.1 - 3.8e-06 25.9 7.7 5.9e-06 25.3 5.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EOO00344.1 - 0.0013 17.7 2.5 0.002 17.1 1.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Oxidored_q6 PF01058.17 EOO00345.1 - 3.8e-22 78.3 0.0 5.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.20 EOO00346.1 - 7.7e-92 307.8 0.0 1.2e-91 307.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EOO00346.1 - 2.4e-22 78.4 16.9 1.3e-11 44.1 4.6 2.7 3 0 0 3 3 3 2 WW domain C2 PF00168.25 EOO00346.1 - 4.1e-17 61.7 0.1 1.1e-16 60.4 0.1 1.8 1 0 0 1 1 1 1 C2 domain GGDEF PF00990.16 EOO00346.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 GGDEF domain RRM_1 PF00076.17 EOO00347.1 - 4.1e-17 61.5 0.0 6.8e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00347.1 - 2.3e-15 56.3 0.0 4.7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO00347.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EOO00347.1 - 0.0056 14.6 0.3 0.0066 14.3 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Packaging_FI PF14000.1 EOO00347.1 - 0.011 15.8 0.4 0.016 15.4 0.3 1.4 1 0 0 1 1 1 0 DNA packaging protein FI IncA PF04156.9 EOO00347.1 - 0.045 13.3 0.8 0.057 13.0 0.5 1.1 1 0 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EOO00347.1 - 0.047 13.9 0.4 0.089 13.0 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CASP_C PF08172.7 EOO00347.1 - 0.053 12.5 0.3 0.072 12.1 0.2 1.1 1 0 0 1 1 1 0 CASP C terminal APG6 PF04111.7 EOO00347.1 - 0.061 12.3 0.8 0.072 12.1 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EOO00347.1 - 0.09 13.1 1.1 0.13 12.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) NPBW PF15180.1 EOO00347.1 - 0.11 12.1 0.2 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Neuropeptides B and W STAT_alpha PF01017.15 EOO00347.1 - 0.11 12.2 1.1 0.15 11.8 0.8 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF904 PF06005.7 EOO00347.1 - 0.14 12.4 5.1 0.22 11.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) EMP24_GP25L PF01105.19 EOO00347.1 - 0.15 11.7 0.4 0.21 11.3 0.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GRP PF07172.6 EOO00347.1 - 1.4 9.4 15.2 0.27 11.7 7.7 1.9 2 0 0 2 2 2 0 Glycine rich protein family DivIC PF04977.10 EOO00347.1 - 3.4 7.2 5.0 4.9 6.7 3.5 1.2 1 0 0 1 1 1 0 Septum formation initiator Nuc_sug_transp PF04142.10 EOO00348.1 - 9.1e-25 87.1 17.8 2.6e-24 85.6 12.3 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EOO00348.1 - 0.00063 19.9 1.1 0.00063 19.9 0.7 3.2 4 0 0 4 4 4 1 Multidrug resistance efflux transporter Adap_comp_sub PF00928.16 EOO00349.1 - 1.7e-61 207.6 0.0 3.9e-61 206.4 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EOO00349.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain WD40 PF00400.27 EOO00350.1 - 1.3e-46 154.8 28.1 5.6e-08 32.3 0.3 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat DUF3639 PF12341.3 EOO00350.1 - 0.00054 19.9 3.3 0.0099 15.8 0.4 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) CPSF_A PF03178.10 EOO00350.1 - 0.0016 17.5 0.0 0.019 14.0 0.0 2.6 2 1 0 2 2 2 1 CPSF A subunit region PD40 PF07676.7 EOO00350.1 - 0.034 13.8 0.1 28 4.5 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 EOO00350.1 - 0.073 11.6 0.0 0.39 9.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.1 EOO00350.1 - 1 9.7 21.0 1.6 9.0 0.1 6.9 7 1 0 7 7 7 0 PQQ-like domain Glyco_hydro_32N PF00251.15 EOO00351.1 - 3.2e-56 190.9 6.2 4.6e-56 190.4 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EOO00351.1 - 0.00062 20.1 0.2 0.0048 17.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Aldedh PF00171.17 EOO00352.1 - 1e-75 254.8 0.0 1.2e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hexapep_2 PF14602.1 EOO00353.1 - 1.1e-17 63.3 23.2 6.4e-10 38.4 1.4 3.3 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EOO00353.1 - 1.3e-17 62.4 21.8 2.3e-10 39.4 1.0 4.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Ribosomal_L27 PF01016.14 EOO00353.1 - 0.023 14.4 0.6 1.1 9.1 0.0 2.6 2 1 1 3 3 3 0 Ribosomal L27 protein UAA PF08449.6 EOO00354.1 - 1.6e-15 56.8 15.6 1.9e-15 56.5 10.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EOO00354.1 - 3.5e-10 39.7 3.5 3.5e-10 39.7 2.5 2.5 2 2 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EOO00354.1 - 0.00023 20.3 1.0 0.00037 19.6 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EOO00354.1 - 0.00027 20.9 26.2 0.00038 20.4 4.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EOO00354.1 - 0.083 11.5 9.3 0.029 13.0 4.4 1.8 1 1 0 1 1 1 0 Phosphate transporter family Peptidase_A24 PF01478.13 EOO00354.1 - 8.9 6.5 12.5 1 9.5 0.1 3.5 1 1 1 3 3 3 0 Type IV leader peptidase family SPX PF03105.14 EOO00355.1 - 4.2e-09 36.5 4.8 1.1e-06 28.6 0.3 3.0 1 1 1 2 2 2 2 SPX domain Peptidase_S10 PF00450.17 EOO00356.1 - 8.8e-111 371.0 0.0 1.1e-110 370.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1206 PF06724.6 EOO00356.1 - 0.057 13.1 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Fungal_trans PF04082.13 EOO00357.1 - 1.6e-15 56.6 0.2 2.6e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO00357.1 - 1.5e-06 27.9 8.9 2.8e-06 27.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypD PF01924.11 EOO00357.1 - 0.25 10.0 1.6 0.38 9.4 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Glyoxalase_2 PF12681.2 EOO00358.1 - 3.3e-11 43.7 0.0 4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EOO00358.1 - 6e-06 26.2 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HABP4_PAI-RBP1 PF04774.10 EOO00359.1 - 0.0037 17.7 3.2 0.0071 16.8 2.3 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family APH PF01636.18 EOO00360.1 - 2.3e-05 24.2 0.2 4.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family NTP_transferase PF00483.18 EOO00360.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EOO00360.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.7 EOO00360.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_tran_28_C PF04101.11 EOO00361.1 - 2.5e-12 46.7 0.0 4.6e-07 29.6 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.4 EOO00362.1 - 7.6e-45 152.0 0.7 1.5e-44 151.1 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Jnk-SapK_ap_N PF09744.4 EOO00362.1 - 9.9 6.1 10.8 1.5 8.8 0.7 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Nucleoporin_C PF03177.9 EOO00363.1 - 4.7e-86 289.5 2.1 6e-86 289.2 1.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EOO00363.1 - 4.1e-70 236.6 0.0 5.2e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like SAP30_Sin3_bdg PF13867.1 EOO00363.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Autotrns_rpt PF12951.2 EOO00363.1 - 0.27 10.9 0.7 0.53 10.0 0.5 1.4 1 0 0 1 1 1 0 Autotransporter-associated beta strand repeat ECR1_N PF14382.1 EOO00364.1 - 4e-13 48.3 0.1 1.1e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EOO00364.1 - 0.0026 17.6 0.1 0.017 15.0 0.0 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EOO00364.1 - 0.011 15.7 2.3 3.9 7.6 0.0 3.6 4 1 0 4 4 4 0 S1 RNA binding domain EMP24_GP25L PF01105.19 EOO00365.1 - 9.9e-56 188.3 0.0 1.1e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FTP PF07504.8 EOO00366.1 - 1.3e-07 30.9 0.1 2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Fungalysin/Thermolysin Propeptide Motif Polyhedrin PF00738.13 EOO00366.1 - 0.01 14.9 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Polyhedrin EGF_CA PF07645.10 EOO00367.1 - 0.0091 15.9 0.4 0.018 15.0 0.3 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 EOO00367.1 - 0.27 11.2 4.3 2.6 8.0 1.3 2.2 2 0 0 2 2 2 0 EGF domain Med7 PF05983.6 EOO00368.1 - 1.2e-53 181.2 0.0 1.4e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 MED7 protein Peptidase_S8 PF00082.17 EOO00369.1 - 0.00014 21.0 0.3 0.00015 21.0 0.2 1.1 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_31 PF01055.21 EOO00370.1 - 3.3e-58 197.5 0.2 4.1e-58 197.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EOO00370.1 - 4.9e-17 61.5 0.3 1.3e-16 60.1 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Proteasome PF00227.21 EOO00371.1 - 9.3e-61 204.4 0.1 1.3e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EOO00371.1 - 6.2e-12 44.6 0.4 1.4e-11 43.5 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EOO00371.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PMM PF03332.8 EOO00372.1 - 5.1e-11 42.5 0.0 6.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EOO00372.1 - 2.7e-10 40.2 0.0 9.6e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EOO00372.1 - 0.025 15.0 0.0 0.042 14.2 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3631 PF12307.3 EOO00372.1 - 0.035 14.0 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) S6PP PF05116.8 EOO00372.1 - 0.043 13.1 0.0 0.6 9.3 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase ISN1 PF06437.6 EOO00372.1 - 0.084 11.5 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase Sugar_tr PF00083.19 EOO00373.1 - 1e-71 241.8 13.2 1.2e-71 241.6 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00373.1 - 3.9e-12 45.5 23.5 3.6e-09 35.7 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_31 PF01055.21 EOO00374.1 - 9.6e-20 70.8 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PAP2 PF01569.16 EOO00375.1 - 3e-23 81.9 0.5 3e-23 81.9 0.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.11 EOO00375.1 - 0.061 13.1 4.5 2.4 8.0 2.5 3.2 3 1 0 3 3 3 0 Colicin V production protein FtsX PF02687.16 EOO00375.1 - 4.5 7.0 9.3 4.1 7.1 0.5 3.1 3 1 0 3 3 3 0 FtsX-like permease family NAD_binding_10 PF13460.1 EOO00376.1 - 1.2e-12 48.2 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO00376.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EOO00376.1 - 5.2e-06 26.0 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EOO00376.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EOO00376.1 - 0.00031 21.0 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EOO00376.1 - 0.0022 16.9 0.1 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EOO00376.1 - 0.0065 15.2 0.1 0.016 13.9 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EOO00376.1 - 0.027 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EOO00376.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RTC PF01137.16 EOO00376.1 - 0.041 12.6 0.0 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase RmlD_sub_bind PF04321.12 EOO00376.1 - 0.043 12.7 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 EOO00376.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1341 PF07071.6 EOO00376.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) Polysacc_synt_2 PF02719.10 EOO00376.1 - 0.092 11.6 0.4 0.17 10.7 0.2 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.16 EOO00376.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HTH_Tnp_Mu_1 PF02316.11 EOO00376.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 1 0 Mu DNA-binding domain TFIIS_M PF07500.9 EOO00377.1 - 5.8e-20 71.4 1.2 5.8e-20 71.4 0.9 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EOO00377.1 - 2.1e-13 50.8 0.0 4.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EOO00377.1 - 5.9e-10 38.6 8.3 1.2e-09 37.7 5.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EOO00377.1 - 0.18 11.5 3.2 0.45 10.2 2.2 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger DUF1974 PF09317.6 EOO00378.1 - 0.16 11.3 2.5 0.34 10.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Peptidase_M36 PF02128.10 EOO00379.1 - 1.3e-100 336.8 3.9 1.5e-100 336.7 2.7 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 EOO00379.1 - 0.0005 19.8 0.1 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 EOO00379.1 - 0.0039 17.2 0.1 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily p450 PF00067.17 EOO00380.1 - 1.3e-23 83.3 0.0 1.5e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EOO00381.1 - 3.3e-20 72.1 28.4 3.3e-20 72.1 19.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily CENP-B_N PF04218.8 EOO00381.1 - 0.025 14.0 0.1 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain ABC_tran PF00005.22 EOO00382.1 - 4.4e-21 75.6 0.0 6.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EOO00382.1 - 0.0016 17.7 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EOO00382.1 - 0.003 16.2 0.1 0.0036 15.9 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EOO00382.1 - 0.033 14.0 0.8 0.3 11.0 0.6 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EOO00382.1 - 0.069 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HET PF06985.6 EOO00383.1 - 4.6e-30 104.6 6.7 1.4e-29 103.0 4.7 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hydrophobin PF01185.13 EOO00384.1 - 0.27 11.6 4.0 1.1 9.7 2.8 1.8 1 1 0 1 1 1 0 Fungal hydrophobin Ald_Xan_dh_C2 PF02738.13 EOO00385.1 - 7.2e-179 595.6 0.1 9.6e-179 595.2 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EOO00385.1 - 4e-40 137.0 0.0 7e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EOO00385.1 - 1.4e-30 105.2 0.1 9.5e-30 102.5 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EOO00385.1 - 1e-29 102.8 0.0 2e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EOO00385.1 - 2.3e-25 88.2 0.0 6.2e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EOO00385.1 - 1.4e-06 27.8 0.7 2.7e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_81 PF03639.8 EOO00386.1 - 3.6e-71 240.1 7.4 3.6e-71 240.1 5.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 81 Fascin PF06268.8 EOO00386.1 - 0.00035 20.6 0.2 0.7 10.0 0.1 2.5 1 1 1 2 2 2 2 Fascin domain RicinB_lectin_2 PF14200.1 EOO00386.1 - 0.0018 18.6 0.8 0.7 10.2 0.1 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.7 EOO00386.1 - 0.11 11.8 2.2 0.52 9.7 0.3 2.0 1 1 1 2 2 2 0 FRG1-like family Vma12 PF11712.3 EOO00387.1 - 1e-36 125.7 0.0 1.3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amino_oxidase PF01593.19 EOO00388.1 - 3.3e-34 118.7 0.0 7.2e-34 117.6 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EOO00388.1 - 9.4e-10 38.3 0.0 4e-09 36.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EOO00388.1 - 0.00055 20.0 0.0 0.0046 17.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO00388.1 - 0.011 14.2 0.3 0.021 13.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EOO00388.1 - 0.13 11.2 0.1 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DIOX_N PF14226.1 EOO00389.1 - 7.6e-13 49.0 0.0 1.2e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO00389.1 - 9.8e-09 35.4 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB PF00651.26 EOO00390.1 - 9.2e-23 80.3 0.0 2.7e-06 27.3 0.0 3.7 3 0 0 3 3 3 3 BTB/POZ domain Pex14_N PF04695.8 EOO00391.1 - 1.4e-20 73.7 1.3 2.4e-20 72.9 0.1 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 EOO00391.1 - 0.00041 20.5 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 RecX family DUF4546 PF15079.1 EOO00391.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Flavi_DEAD PF07652.9 EOO00391.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DASH_Dam1 PF08653.5 EOO00391.1 - 0.22 11.3 0.4 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 XhlA PF10779.4 EOO00391.1 - 0.29 11.0 1.2 6.8 6.6 0.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF3337 PF11816.3 EOO00392.1 - 1.3e-94 317.3 0.1 1.9e-90 303.6 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EOO00392.1 - 1.1e-32 110.7 7.8 3.5e-07 29.8 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Mito_carr PF00153.22 EOO00393.1 - 3.5e-68 225.3 5.0 5.8e-25 86.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PAPA-1 PF04795.7 EOO00394.1 - 8.1e-25 87.3 4.3 8.1e-25 87.3 3.0 3.1 3 0 0 3 3 3 1 PAPA-1-like conserved region UbiA PF01040.13 EOO00395.1 - 4e-30 104.8 14.0 4.7e-30 104.6 9.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family GET2 PF08690.5 EOO00396.1 - 2.3e-10 40.1 0.8 2.4e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 GET complex subunit GET2 DUF390 PF04094.9 EOO00396.1 - 0.3 9.0 8.9 0.43 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) S10_plectin PF03501.10 EOO00397.1 - 1.7e-38 130.3 0.1 2e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain COX6B PF02297.12 EOO00398.1 - 3.1e-18 65.5 4.4 3.7e-18 65.3 3.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EOO00398.1 - 0.0055 16.0 0.4 0.0078 15.5 0.3 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EOO00398.1 - 0.017 14.6 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Fzo_mitofusin PF04799.8 EOO00399.1 - 0.022 14.1 0.4 0.025 13.9 0.2 1.0 1 0 0 1 1 1 0 fzo-like conserved region DUF2951 PF11166.3 EOO00399.1 - 0.33 10.8 2.6 0.43 10.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) IncA PF04156.9 EOO00399.1 - 3.9 7.0 8.2 4.7 6.7 5.7 1.1 1 0 0 1 1 1 0 IncA protein ADK PF00406.17 EOO00400.1 - 1.1e-58 197.3 0.0 1.5e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EOO00400.1 - 3e-14 52.4 0.0 7.7e-14 51.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EOO00400.1 - 3.9e-06 27.6 0.0 6.8e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EOO00400.1 - 5.8e-05 22.9 0.0 0.00017 21.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EOO00400.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EOO00400.1 - 0.033 14.5 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4066 PF13278.1 EOO00401.1 - 2.3e-16 59.5 0.0 3.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EOO00401.1 - 8.8e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Gon7 PF08738.5 EOO00402.1 - 5.3e-13 48.8 9.1 3.1e-12 46.3 6.3 1.8 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 EOO00402.1 - 0.076 13.1 4.7 0.092 12.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Evr1_Alr PF04777.8 EOO00402.1 - 0.11 12.3 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Erv1 / Alr family Coprogen_oxidas PF01218.13 EOO00403.1 - 1.6e-133 443.8 0.2 2.1e-133 443.4 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIM PF04434.12 EOO00403.1 - 0.53 9.8 3.2 13 5.3 0.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger Brix PF04427.13 EOO00405.1 - 4.5e-38 130.8 0.1 5.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyco_transf_90 PF05686.7 EOO00406.1 - 0.015 14.0 0.2 0.017 13.8 0.2 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 RR_TM4-6 PF06459.7 EOO00406.1 - 2.4 7.9 6.4 2.8 7.7 4.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Inhibitor_I9 PF05922.11 EOO00407.1 - 0.019 15.5 0.4 0.031 14.8 0.3 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Gp_dh_C PF02800.15 EOO00408.1 - 1.3e-74 248.8 0.0 2.1e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EOO00408.1 - 1.7e-60 203.3 0.1 2.7e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EOO00408.1 - 0.0051 16.7 0.1 0.012 15.5 0.1 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EOO00408.1 - 0.019 14.5 0.1 0.044 13.3 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MitMem_reg PF13012.1 EOO00409.1 - 5.4e-38 129.6 0.4 1.4e-37 128.2 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EOO00409.1 - 5.9e-29 100.1 0.3 1.2e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SRA1 PF07304.6 EOO00411.1 - 9.4e-11 41.6 0.0 9.4e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EOO00411.1 - 0.0011 18.7 0.1 0.012 15.4 0.1 1.9 1 1 1 2 2 2 1 Prp18 domain DUF3422 PF11902.3 EOO00411.1 - 0.11 11.4 0.1 0.13 11.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) C2 PF00168.25 EOO00412.1 - 3.4e-20 71.6 0.4 8.9e-14 51.0 0.0 3.0 3 0 0 3 3 3 2 C2 domain BTB PF00651.26 EOO00413.1 - 0.00074 19.4 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain B12D PF06522.6 EOO00414.1 - 7.6e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4632 PF15451.1 EOO00414.1 - 9.1 6.2 6.9 6 6.8 0.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4632) PTH2 PF01981.11 EOO00415.1 - 3.4e-46 155.6 0.2 4.3e-46 155.3 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hom_end PF05204.9 EOO00415.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease BING4CT PF08149.6 EOO00416.1 - 7.8e-41 137.4 0.0 2.1e-37 126.4 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EOO00416.1 - 1.5e-08 34.2 0.0 3e-05 23.7 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EOO00416.1 - 0.00044 19.1 0.0 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region TauD PF02668.11 EOO00417.1 - 2.4e-47 161.8 0.2 2.8e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EOO00417.1 - 0.014 15.9 0.5 6.8 7.2 0.1 2.8 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.16 EOO00418.1 - 5.4e-10 39.1 0.1 3.1e-09 36.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO00418.1 - 0.0028 16.5 0.1 0.21 10.4 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Hist_deacetyl PF00850.14 EOO00419.1 - 8.1e-90 301.2 0.0 1.1e-89 300.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EOO00419.1 - 1.1e-39 135.6 0.3 4.7e-39 133.6 0.1 1.9 2 0 0 2 2 2 1 Arb2 domain JmjC PF02373.17 EOO00420.1 - 3.2e-10 40.2 0.1 1.2e-09 38.3 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EOO00420.1 - 4.1e-07 30.0 9.0 4.1e-07 30.0 6.2 2.7 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EOO00420.1 - 0.01 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain HOOK PF05622.7 EOO00421.1 - 2.8e-07 28.7 98.1 5.7e-07 27.7 0.0 3.5 2 1 1 3 3 3 1 HOOK protein CH PF00307.26 EOO00421.1 - 0.014 15.4 0.0 0.048 13.6 0.0 2.0 1 0 0 1 1 1 0 Calponin homology (CH) domain Mito_carr PF00153.22 EOO00422.1 - 1.4e-30 104.8 1.5 4.5e-17 61.5 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein cobW PF02492.14 EOO00423.1 - 2.6e-35 121.4 0.0 3.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EOO00423.1 - 3.4e-05 22.7 0.8 0.00056 18.7 0.5 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EOO00423.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EOO00423.1 - 0.0051 17.1 0.0 0.0064 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EOO00423.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 EOO00423.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EOO00423.1 - 0.058 14.2 0.3 0.096 13.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EOO00423.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 EOO00423.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EOO00423.1 - 0.14 11.5 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.1 EOO00423.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 EOO00423.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Epimerase PF01370.16 EOO00424.1 - 1.9e-16 60.2 0.1 5.4e-16 58.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO00424.1 - 2.1e-10 40.9 0.2 7e-10 39.2 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EOO00424.1 - 1.5e-08 33.7 0.0 2.6e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EOO00424.1 - 1.3e-06 27.8 0.1 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.7 EOO00424.1 - 1.8e-05 23.8 0.0 7.5e-05 21.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein ADH_N PF08240.7 EOO00425.1 - 6.4e-36 122.4 0.9 2e-35 120.8 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO00425.1 - 4.2e-17 61.9 0.0 7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO00425.1 - 1.3e-05 26.1 0.0 2.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EOO00425.1 - 0.003 16.6 0.4 0.0052 15.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Saccharop_dh PF03435.13 EOO00425.1 - 0.0042 16.1 0.0 0.005 15.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1953 PF09196.5 EOO00425.1 - 0.0099 15.5 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1953) NAD_binding_7 PF13241.1 EOO00425.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2318 PF10080.4 EOO00425.1 - 0.062 13.0 0.5 13 5.6 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) NAD_binding_8 PF13450.1 EOO00425.1 - 0.074 13.0 0.2 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NADH_4Fe-4S PF10589.4 EOO00425.1 - 2.2 7.5 4.9 0.5 9.5 0.6 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region RRM_1 PF00076.17 EOO00426.1 - 5.8e-19 67.4 0.0 8e-19 67.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00426.1 - 7e-15 54.7 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO00426.1 - 1.9e-11 43.5 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EOO00426.1 - 0.011 15.4 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 Limkain b1 DUF663 PF04950.7 EOO00427.1 - 2.5e-105 351.7 0.0 3.4e-105 351.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EOO00427.1 - 1.9e-20 72.1 0.0 4.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosom_S12_S23 PF00164.20 EOO00428.1 - 6.7e-41 138.5 0.4 7.8e-41 138.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 WD40 PF00400.27 EOO00429.1 - 2e-21 75.0 0.1 3.7e-06 26.6 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.2 EOO00429.1 - 3.4e-07 30.2 0.2 7.4e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 EOO00429.1 - 0.054 13.0 0.0 1.2 8.7 0.0 3.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Nha1_C PF08619.5 EOO00430.1 - 0.06 12.6 0.7 0.069 12.4 0.5 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Atg8 PF02991.11 EOO00431.1 - 2.9e-51 171.7 0.2 3.4e-51 171.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EOO00431.1 - 2.8e-06 27.4 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4050 PF13259.1 EOO00432.1 - 3.9e-21 75.2 0.6 6.3e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) DUF4098 PF13345.1 EOO00433.1 - 0.03 14.2 7.0 20 5.2 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4098) SART-1 PF03343.8 EOO00434.1 - 7.5e-156 520.0 50.6 8.6e-156 519.8 35.1 1.0 1 0 0 1 1 1 1 SART-1 family HLH PF00010.21 EOO00435.1 - 1.8e-07 30.7 0.0 1.1e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Pup PF05639.6 EOO00435.1 - 2.4 8.7 6.4 3.1 8.3 0.1 2.7 2 0 0 2 2 2 0 Pup-like protein LMBR1 PF04791.11 EOO00435.1 - 2.7 6.4 7.7 4.1 5.8 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Telomere_Sde2 PF13019.1 EOO00436.1 - 2e-50 170.6 2.7 3.2e-50 169.9 1.9 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF1675 PF07897.6 EOO00436.1 - 0.0012 18.7 8.2 0.0015 18.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) LacI PF00356.16 EOO00436.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family LIM_bind PF01803.11 EOO00437.1 - 2.2e-78 262.6 0.1 3.3e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 LIM-domain binding protein DUF3712 PF12505.3 EOO00439.1 - 8.5e-12 45.1 0.3 4e-11 43.0 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) Ras PF00071.17 EOO00440.1 - 2.1e-63 212.5 0.2 2.4e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO00440.1 - 2e-21 76.7 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO00440.1 - 3.9e-13 49.0 0.1 5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EOO00440.1 - 3e-08 33.6 0.1 4.8e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EOO00440.1 - 4.6e-05 22.9 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EOO00440.1 - 9.8e-05 21.6 0.1 0.00016 20.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EOO00440.1 - 0.00012 22.2 0.1 0.00032 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EOO00440.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EOO00440.1 - 0.002 17.2 0.1 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EOO00440.1 - 0.0026 16.9 0.1 0.0063 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EOO00440.1 - 0.0074 16.2 0.1 0.095 12.6 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EOO00440.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EOO00440.1 - 0.017 14.6 0.1 0.069 12.7 0.0 1.7 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EOO00440.1 - 0.018 15.3 0.1 0.025 14.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EOO00440.1 - 0.023 14.6 0.3 0.043 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EOO00440.1 - 0.09 12.0 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EOO00440.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EOO00440.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) EF-hand_1 PF00036.27 EOO00441.1 - 1.5e-21 73.9 3.7 6e-06 25.1 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EOO00441.1 - 1.2e-19 70.1 2.8 7.4e-13 48.4 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EOO00441.1 - 1.4e-19 68.4 7.2 1.8e-06 27.0 0.4 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EOO00441.1 - 4.1e-17 60.4 2.9 1.6e-05 24.3 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EOO00441.1 - 3.8e-16 58.4 6.6 0.00017 21.1 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EOO00441.1 - 3.7e-07 30.1 0.0 3.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EOO00441.1 - 0.00049 19.7 0.3 0.22 11.2 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EOO00441.1 - 0.0013 18.4 0.6 1.4 8.6 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CBM_20 PF00686.14 EOO00442.1 - 7e-32 108.8 0.3 8.6e-32 108.6 0.2 1.1 1 0 0 1 1 1 1 Starch binding domain Fn3-like PF14310.1 EOO00442.1 - 0.028 14.3 0.0 1.4 8.8 0.0 2.5 3 0 0 3 3 3 0 Fibronectin type III-like domain SPX PF03105.14 EOO00443.1 - 1.7e-40 139.5 10.6 1.7e-40 139.5 7.3 3.5 2 2 0 2 2 2 1 SPX domain Vps39_1 PF10366.4 EOO00443.1 - 2.9e-34 117.3 0.1 1.4e-32 111.9 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Na_sulph_symp PF00939.14 EOO00443.1 - 3.8e-28 98.5 45.1 7.2e-20 71.3 18.2 2.1 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EOO00443.1 - 3e-14 52.3 42.3 9.4e-09 34.3 18.4 2.5 2 1 0 2 2 2 2 Citrate transporter CNH PF00780.17 EOO00443.1 - 6.8e-07 28.9 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EOO00443.1 - 0.0014 18.2 5.1 0.0021 17.6 0.2 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Apc3 PF12895.2 EOO00443.1 - 0.049 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HbrB PF08539.6 EOO00444.1 - 1e-54 184.6 0.0 1.7e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 HbrB-like IncA PF04156.9 EOO00445.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 IncA protein V-SNARE_C PF12352.3 EOO00446.1 - 2.4e-15 56.3 1.2 5e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EOO00446.1 - 0.00025 20.6 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 EOO00446.1 - 0.12 11.7 0.1 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TrbI_Ftype PF09677.5 EOO00446.1 - 0.16 11.8 0.5 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) MFS_1 PF07690.11 EOO00447.1 - 1.5e-50 171.9 22.3 1.5e-50 171.9 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00447.1 - 3.4e-14 52.2 10.1 9.1e-13 47.5 4.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EOO00447.1 - 2.1e-06 26.2 6.8 3.2e-06 25.6 4.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EOO00447.1 - 0.0015 16.7 7.3 0.0015 16.7 5.0 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF791 PF05631.9 EOO00447.1 - 0.0089 14.7 5.7 0.021 13.5 2.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF791) OAD_gamma PF04277.8 EOO00447.1 - 0.11 12.8 0.1 0.98 9.8 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PgaD PF13994.1 EOO00447.1 - 2.4 7.6 5.4 4.8 6.6 0.0 3.2 3 0 0 3 3 3 0 PgaD-like protein Asp PF00026.18 EOO00448.1 - 7.3e-60 202.8 1.0 8.7e-60 202.6 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO00448.1 - 7e-07 29.3 1.0 8.4e-06 25.8 0.0 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EOO00448.1 - 2e-06 27.4 0.0 0.00033 20.2 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EOO00448.1 - 0.0016 18.9 0.7 0.088 13.3 0.2 3.3 2 1 0 2 2 2 1 Aspartyl protease TPK_B1_binding PF04265.9 EOO00449.1 - 5.5e-24 83.6 0.1 8e-24 83.1 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EOO00449.1 - 2.2e-16 59.5 0.1 3.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain FDF PF09532.5 EOO00450.1 - 0.026 15.0 3.2 0.048 14.1 2.2 1.4 1 0 0 1 1 1 0 FDF domain Gp-FAR-1 PF05823.7 EOO00450.1 - 0.05 13.5 1.5 0.068 13.1 1.0 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1469 PF07332.6 EOO00450.1 - 0.11 12.1 1.5 0.22 11.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) ExoD PF06055.7 EOO00450.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD NYN_YacP PF05991.6 EOO00450.1 - 0.23 11.2 2.6 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 YacP-like NYN domain RR_TM4-6 PF06459.7 EOO00450.1 - 3.2 7.5 5.9 4.2 7.1 4.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GFA PF04828.9 EOO00451.1 - 6.7e-18 64.4 6.0 2.7e-09 36.8 1.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EOO00452.1 - 1.9e-06 27.6 4.6 3.1e-06 26.9 3.2 1.4 1 0 0 1 1 1 1 CHCH domain Pro-kuma_activ PF09286.6 EOO00453.1 - 9.4e-40 135.9 0.0 3.1e-39 134.2 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EOO00453.1 - 0.00013 21.2 0.6 0.00027 20.1 0.3 1.5 2 0 0 2 2 2 1 Subtilase family WD40 PF00400.27 EOO00454.1 - 6.3e-20 70.2 21.1 2.6e-08 33.4 0.8 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EOO00454.1 - 0.00012 21.8 0.4 0.021 14.5 0.0 2.6 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EOO00454.1 - 0.00031 20.0 0.2 0.014 14.6 0.0 2.7 2 1 0 3 3 3 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EOO00454.1 - 0.00094 17.5 0.1 0.0025 16.1 0.1 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 EOO00454.1 - 0.0011 17.2 0.4 0.088 10.9 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 adh_short PF00106.20 EOO00456.1 - 2.6e-27 95.7 0.6 3.2e-27 95.4 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00456.1 - 6.5e-12 45.4 0.4 8.4e-12 45.1 0.3 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO00456.1 - 4.7e-11 42.9 0.0 6e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO00456.1 - 5.1e-06 26.1 0.1 5.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO00456.1 - 2.2e-05 24.5 0.3 3.3e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EOO00456.1 - 0.0043 16.7 0.4 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EOO00456.1 - 0.015 14.2 0.1 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EOO00456.1 - 0.07 12.1 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2419 PF10343.4 EOO00457.1 - 1.2e-134 448.0 0.1 1.4e-134 447.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) EHN PF06441.7 EOO00458.1 - 4e-33 113.6 0.1 6e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EOO00458.1 - 5.4e-08 33.0 0.0 4.8e-07 29.8 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00458.1 - 1.6e-07 31.1 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_7 PF03492.10 EOO00458.1 - 0.047 12.4 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DNA_pol_delta_4 PF04081.8 EOO00459.1 - 2e-33 115.2 3.2 4.6e-33 114.1 2.2 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF2376 PF09550.5 EOO00459.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) ThiF PF00899.16 EOO00460.1 - 9.2e-42 142.0 1.3 1.3e-41 141.5 0.1 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EOO00460.1 - 6.3e-31 105.7 1.8 2.6e-30 103.7 0.1 2.5 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EOO00460.1 - 2.2e-21 75.7 2.8 3.1e-21 75.2 0.9 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EOO00460.1 - 9.7e-19 66.4 0.6 9.7e-19 66.4 0.4 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EOO00460.1 - 0.00025 21.1 0.1 0.00061 19.9 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EOO00460.1 - 0.00042 20.5 0.1 0.0014 18.8 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Guanylate_kin PF00625.16 EOO00461.1 - 2.1e-55 187.0 0.1 2.5e-55 186.7 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.18 EOO00461.1 - 0.0044 16.9 0.0 0.0056 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EOO00461.1 - 0.0058 16.5 0.1 0.027 14.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF3650 PF12368.3 EOO00461.1 - 0.45 10.0 2.2 15 5.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Septin PF00735.13 EOO00462.1 - 1.6e-108 362.0 0.5 1.9e-108 361.7 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EOO00462.1 - 1.6e-06 28.0 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EOO00462.1 - 8.2e-06 25.0 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EOO00462.1 - 8.3e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EOO00462.1 - 0.00011 21.6 0.5 0.015 14.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EOO00462.1 - 0.0011 18.8 0.5 1.3 8.8 0.1 2.4 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EOO00462.1 - 0.0026 17.2 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EOO00462.1 - 0.011 15.9 0.0 0.034 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EOO00462.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EOO00462.1 - 0.015 15.5 0.5 0.025 14.8 0.3 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 EOO00462.1 - 0.016 14.3 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EOO00462.1 - 0.023 15.0 0.0 0.038 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EOO00462.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EOO00462.1 - 0.04 12.7 0.1 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EOO00462.1 - 0.046 12.6 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EOO00462.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EOO00462.1 - 0.35 10.7 1.7 0.58 10.0 0.0 2.3 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.11 EOO00463.1 - 1.3e-14 53.7 32.9 1.9e-14 53.1 22.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EOO00463.1 - 1.2e-07 31.4 8.5 1.2e-07 31.4 5.9 2.7 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 SSF PF00474.12 EOO00464.1 - 1.2e-06 27.4 4.7 1.2e-06 27.4 3.3 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family GMC_oxred_C PF05199.8 EOO00465.1 - 2.4e-17 63.5 0.0 5.6e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EOO00465.1 - 1.5e-06 27.5 0.0 4e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase DOT1 PF08123.8 EOO00465.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PAP2 PF01569.16 EOO00466.1 - 3.2e-16 59.1 5.6 8e-16 57.8 3.9 1.7 1 0 0 1 1 1 1 PAP2 superfamily Autophagy_N PF03986.8 EOO00467.1 - 6.6e-44 149.2 0.0 1.7e-43 147.8 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EOO00467.1 - 1.8e-22 79.2 1.3 2.1e-22 79.0 0.2 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EOO00467.1 - 2.1e-14 52.3 0.5 3.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Acyltransferase PF01553.16 EOO00468.1 - 2e-09 37.0 0.0 4.6e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DUF1581 PF07619.6 EOO00468.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) RRM_1 PF00076.17 EOO00470.1 - 3.8e-30 103.3 0.0 2.6e-12 46.2 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00470.1 - 2.9e-20 72.0 0.0 2.4e-05 24.2 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO00470.1 - 2.1e-16 59.5 0.0 1.6e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EOO00470.1 - 0.064 13.0 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SF3b1 PF08920.5 EOO00471.1 - 1.6e-36 125.5 5.2 7.5e-35 120.0 0.1 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EOO00471.1 - 3.6e-15 55.9 3.0 0.01 16.1 0.0 7.3 6 3 3 9 9 9 6 HEAT repeats HEAT_EZ PF13513.1 EOO00471.1 - 9.2e-12 45.0 0.7 0.34 11.4 0.0 7.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EOO00471.1 - 2.8e-11 42.5 9.7 1 9.6 0.0 9.6 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EOO00471.1 - 3.1e-06 27.4 0.2 0.51 10.7 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EOO00471.1 - 0.00027 19.4 0.2 0.13 10.6 0.0 3.2 2 2 0 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 EOO00471.1 - 0.00066 18.2 0.0 0.0012 17.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 EOO00471.1 - 0.0086 15.4 0.4 4.8 6.4 0.0 3.7 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EOO00471.1 - 0.0094 15.3 0.2 1.3 8.3 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal DUF2890 PF11081.3 EOO00471.1 - 0.46 10.5 9.3 1.8 8.6 6.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) LSM PF01423.17 EOO00472.1 - 9.9e-15 53.8 0.0 1.8e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EOO00472.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 EOO00472.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Ribosomal_S13_N PF08069.7 EOO00473.1 - 5.7e-30 102.9 0.1 1.1e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EOO00473.1 - 3.7e-23 81.0 0.1 7.6e-23 80.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 EOO00473.1 - 0.0066 16.1 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 'Paired box' domain VRR_NUC PF08774.6 EOO00474.1 - 4e-18 65.2 0.0 8.1e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain bZIP_1 PF00170.16 EOO00475.1 - 0.00067 19.5 10.1 0.0013 18.6 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EOO00475.1 - 0.084 12.8 1.1 0.18 11.7 0.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family PAP1 PF08601.5 EOO00475.1 - 2.5 7.6 4.3 4.1 6.9 0.0 2.6 2 1 1 3 3 3 0 Transcription factor PAP1 DUF904 PF06005.7 EOO00475.1 - 3.2 8.1 8.9 0.25 11.6 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EOO00475.1 - 8.7 6.2 13.6 40 4.1 8.7 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Dpy-30 PF05186.8 EOO00476.1 - 3.1e-15 55.3 0.0 4.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif CBFB_NFYA PF02045.10 EOO00477.1 - 5e-30 103.8 4.3 9.4e-30 102.9 3.0 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B FAM163 PF15069.1 EOO00477.1 - 0.064 13.8 0.2 0.13 12.8 0.1 1.5 1 1 0 1 1 1 0 FAM163 family PAT1 PF09770.4 EOO00477.1 - 0.67 8.1 15.6 0.67 8.1 10.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 EOO00478.1 - 1.3e-45 155.6 0.0 1.7e-39 135.5 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00478.1 - 2.5e-21 75.9 0.0 4.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.19 EOO00478.1 - 6.6e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EOO00478.1 - 3.8e-08 32.6 0.0 1.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EOO00478.1 - 6.8e-06 25.9 0.0 0.0029 17.3 0.1 2.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.1 EOO00478.1 - 0.0087 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EOO00478.1 - 0.026 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EOO00478.1 - 0.073 11.8 0.1 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.19 EOO00478.1 - 0.12 12.1 0.1 0.5 10.1 0.0 2.1 1 1 1 2 2 2 0 PAS fold DRMBL PF07522.9 EOO00479.1 - 7.5e-31 106.4 0.0 1.7e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EOO00479.1 - 2.5e-11 43.5 0.0 5.6e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EOO00479.1 - 0.074 12.6 0.2 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Cullin PF00888.17 EOO00480.1 - 3.6e-130 435.2 0.7 4.9e-130 434.8 0.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EOO00480.1 - 9.4e-27 92.6 1.1 2.7e-26 91.1 0.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain MarR_2 PF12802.2 EOO00480.1 - 0.06 13.0 0.0 8.4 6.1 0.0 3.1 2 0 0 2 2 2 0 MarR family Rrf2 PF02082.15 EOO00480.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator CwfJ_C_2 PF04676.9 EOO00481.1 - 4.8e-21 75.0 0.2 1.1e-20 73.9 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EOO00481.1 - 3.9e-19 68.5 0.0 6.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.7 EOO00483.1 - 1.9e-41 140.7 0.0 7.8e-41 138.7 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT_2 PF13646.1 EOO00483.1 - 0.00088 19.5 7.8 1.2 9.4 0.1 6.6 6 2 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EOO00483.1 - 0.0038 17.5 1.3 1.1 9.6 0.0 5.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CheR_N PF03705.10 EOO00483.1 - 0.017 14.5 0.0 0.064 12.6 0.0 2.0 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain HEAT PF02985.17 EOO00483.1 - 0.12 12.4 20.8 1.1 9.4 0.0 8.5 10 0 0 10 10 10 0 HEAT repeat Sulfatase PF00884.18 EOO00484.1 - 1e-54 185.8 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EOO00484.1 - 7.3e-26 89.7 3.9 1.6e-24 85.4 0.6 2.7 1 1 1 2 2 2 2 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EOO00484.1 - 6.3e-10 38.9 0.4 1.9e-07 30.7 0.3 2.7 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EOO00484.1 - 0.0014 17.1 0.0 0.002 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF3524 PF12038.3 EOO00484.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) Tox-HDC PF15656.1 EOO00484.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature MFS_1 PF07690.11 EOO00485.1 - 1.1e-11 44.1 11.3 1.4e-11 43.7 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF983 PF06170.7 EOO00485.1 - 0.25 11.4 3.0 0.35 10.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Chromo PF00385.19 EOO00486.1 - 5e-16 58.1 0.5 8e-16 57.4 0.3 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SLAIN PF15301.1 EOO00486.1 - 0.27 10.3 10.3 0.35 9.9 7.2 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family Mitofilin PF09731.4 EOO00486.1 - 7.8 5.0 9.4 8.8 4.8 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DAHP_synth_2 PF01474.11 EOO00487.1 - 4.3e-194 644.9 0.0 4.9e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family RNase_P_p30 PF01876.11 EOO00488.1 - 1.4e-44 150.9 0.0 2.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Rif1_N PF12231.3 EOO00490.1 - 1.1e-96 324.0 0.6 1.2e-96 323.8 0.4 1.0 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DUF3050 PF11251.3 EOO00490.1 - 0.0082 15.4 0.0 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3050) AcylCoA_dehyd_C PF12186.3 EOO00490.1 - 0.03 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Epimerase PF01370.16 EOO00491.1 - 1.7e-09 37.5 0.0 0.00025 20.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO00491.1 - 1.2e-07 31.8 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO00491.1 - 7e-07 28.7 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EOO00491.1 - 0.00073 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EOO00491.1 - 0.0057 15.3 0.0 0.17 10.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EOO00491.1 - 0.014 14.3 0.0 0.058 12.3 0.0 1.7 1 1 0 2 2 2 0 Male sterility protein PQ-loop PF04193.9 EOO00492.1 - 3.4e-25 87.3 7.6 6.3e-14 51.2 1.9 2.5 2 0 0 2 2 2 2 PQ loop repeat WLM PF08325.5 EOO00493.1 - 6.4e-53 179.3 0.0 1.1e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EOO00493.1 - 6.2e-08 31.6 16.0 7.6e-07 28.1 1.1 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EOO00493.1 - 0.00087 19.0 6.7 0.0095 15.7 4.9 2.2 1 1 1 2 2 2 2 Double zinc ribbon DUF45 PF01863.12 EOO00493.1 - 0.05 13.4 0.4 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 ALMT PF11744.3 EOO00493.1 - 0.069 11.7 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RecR PF02132.10 EOO00493.1 - 0.89 9.0 4.7 1.4 8.4 0.9 2.8 2 1 0 2 2 2 0 RecR protein zf-HIT PF04438.11 EOO00493.1 - 2.4 7.8 8.2 4.3 7.0 0.3 2.3 2 0 0 2 2 2 0 HIT zinc finger OrfB_Zn_ribbon PF07282.6 EOO00493.1 - 3.8 7.2 7.7 2.2 7.9 1.5 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 EOO00493.1 - 9 5.9 16.0 0.4 10.2 0.8 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Asp PF00026.18 EOO00494.1 - 3.2e-76 256.5 7.3 3.9e-76 256.3 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO00494.1 - 2.7e-07 30.7 0.3 2.7e-06 27.4 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO00494.1 - 0.00029 21.2 3.6 0.0078 16.6 0.7 3.5 3 1 0 3 3 3 1 Aspartyl protease Cupin_2 PF07883.6 EOO00495.1 - 9.5e-05 21.8 0.0 0.00044 19.6 0.0 2.1 1 1 0 1 1 1 1 Cupin domain Med8 PF10232.4 EOO00496.1 - 1.3e-19 70.6 1.3 4e-19 69.0 0.2 1.9 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 Voldacs PF03517.8 EOO00496.1 - 0.11 12.3 2.8 5.5 6.8 0.5 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling CENP-B_dimeris PF09026.5 EOO00496.1 - 1.7 8.9 14.0 0.85 9.8 2.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.13 EOO00496.1 - 7.5 5.6 8.7 3.9 6.5 1.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF4611 PF15387.1 EOO00496.1 - 8.8 6.5 13.4 10 6.3 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HisKA PF00512.20 EOO00497.1 - 2e-22 78.9 0.1 9e-22 76.8 0.1 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EOO00497.1 - 1.5e-18 67.0 0.0 5.7e-12 45.9 0.0 3.5 3 1 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EOO00497.1 - 3.9e-18 65.3 0.2 2.3e-17 62.8 0.2 2.3 2 0 0 2 2 2 1 PAS fold Response_reg PF00072.19 EOO00497.1 - 7.1e-18 64.6 0.1 2.2e-17 63.0 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.5 EOO00497.1 - 9.8e-12 44.8 1.3 6.3e-07 29.4 0.0 4.2 3 2 0 3 3 3 2 PAS fold HATPase_c PF02518.21 EOO00497.1 - 5.7e-11 42.1 0.1 1.2e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.19 EOO00497.1 - 1.5e-09 37.6 0.0 3.5e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold GRIP PF01465.15 EOO00497.1 - 0.14 11.7 0.0 0.89 9.1 0.0 2.3 2 0 0 2 2 2 0 GRIP domain ProRS-C_1 PF09180.6 EOO00498.1 - 0.078 12.9 0.4 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal COesterase PF00135.23 EOO00499.1 - 2.3e-06 26.6 0.0 2.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family SMC_Nse1 PF07574.8 EOO00499.1 - 0.063 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Aldose_epim PF01263.15 EOO00500.1 - 4.7e-41 140.8 0.0 6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase BRCT PF00533.21 EOO00501.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.14 EOO00501.1 - 6.8 6.7 14.2 3.8 7.4 0.9 4.1 3 0 0 3 3 3 0 AT hook motif Ric8 PF10165.4 EOO00502.1 - 2e-113 379.6 0.5 2.2e-113 379.4 0.4 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF1295 PF06966.7 EOO00505.1 - 8.5e-56 188.8 0.2 1.1e-55 188.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EOO00505.1 - 5.9e-06 26.1 2.8 1.3e-05 24.9 0.0 2.7 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EOO00505.1 - 1.1e-05 25.5 0.6 3.7e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EOO00505.1 - 0.0036 17.3 0.0 0.0036 17.3 0.0 3.0 4 1 1 5 5 5 1 Phospholipid methyltransferase Rhodanese PF00581.15 EOO00506.1 - 6e-13 49.1 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain TPR_1 PF00515.23 EOO00507.1 - 1.6e-53 176.2 34.7 2e-08 33.5 0.0 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EOO00507.1 - 1.1e-47 156.1 26.1 2.7e-07 29.9 0.0 10.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EOO00507.1 - 3.5e-46 154.7 25.8 5.4e-14 51.5 0.6 6.4 4 1 1 6 6 6 6 TPR repeat TPR_8 PF13181.1 EOO00507.1 - 2.1e-39 130.3 26.2 3.5e-07 29.5 0.0 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00507.1 - 2.6e-34 117.1 20.4 1.1e-08 35.5 0.0 6.9 5 1 3 8 8 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EOO00507.1 - 3.5e-31 106.9 23.1 5.9e-08 32.5 0.2 6.8 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EOO00507.1 - 3e-30 101.8 22.5 0.00077 19.4 0.0 10.8 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EOO00507.1 - 7.1e-29 97.6 15.3 7.5e-05 23.0 0.0 9.7 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_19 PF14559.1 EOO00507.1 - 2.2e-25 88.7 21.1 0.0002 21.6 0.2 6.5 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 EOO00507.1 - 7.1e-24 82.5 16.6 0.00023 21.4 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 EOO00507.1 - 2.1e-21 73.9 15.5 0.0015 18.1 0.0 9.9 8 2 1 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EOO00507.1 - 6.7e-15 54.9 16.3 1.3e-08 34.8 1.4 4.3 3 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EOO00507.1 - 1.8e-13 50.1 11.0 0.00088 19.0 0.1 6.9 2 1 7 9 9 9 6 Tetratricopeptide repeat TPR_15 PF13429.1 EOO00507.1 - 2.8e-11 42.9 11.7 0.0017 17.4 0.3 4.3 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EOO00507.1 - 7.9e-05 22.4 17.6 0.26 11.2 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 EOO00507.1 - 0.00038 20.5 9.9 0.23 11.6 0.0 4.4 5 1 1 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EOO00507.1 - 0.00088 19.1 0.4 27 4.7 0.0 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EOO00507.1 - 0.0013 18.6 20.4 0.0078 16.1 0.0 4.7 4 2 2 6 6 6 2 Tetratricopeptide repeat DUF2225 PF09986.4 EOO00507.1 - 0.0015 18.0 3.7 0.91 8.9 0.0 3.6 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) GAS PF13851.1 EOO00507.1 - 0.083 12.0 2.1 0.13 11.4 0.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SNAP PF14938.1 EOO00507.1 - 0.67 9.0 16.7 3.7 6.6 1.0 4.5 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP Chorismate_bind PF00425.13 EOO00508.1 - 1.9e-89 299.4 0.0 1.5e-87 293.2 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 EOO00508.1 - 1.7e-29 102.5 0.2 3e-26 92.1 0.0 3.4 2 1 0 2 2 2 2 Anthranilate synthase component I, N terminal region DUF1751 PF08551.5 EOO00509.1 - 0.016 15.5 0.2 0.016 15.5 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Ribosomal_L3 PF00297.17 EOO00511.1 - 1.1e-114 382.2 7.9 1.3e-114 382.0 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 MFS_1 PF07690.11 EOO00512.1 - 1.8e-35 122.3 41.0 1.8e-35 122.3 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00512.1 - 1.2e-11 43.8 16.7 1.2e-11 43.8 11.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MAP65_ASE1 PF03999.7 EOO00512.1 - 3.2 6.2 4.9 4.4 5.7 3.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.26 EOO00513.1 - 1.2e-23 82.6 0.9 2.4e-23 81.6 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain AA_permease PF00324.16 EOO00514.1 - 1.8e-119 399.2 39.3 2.1e-119 399.0 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO00514.1 - 2e-37 128.7 40.4 2.4e-37 128.4 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EOO00516.1 - 3.2e-51 174.3 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EOO00517.1 - 2.8e-19 69.0 12.1 2.8e-19 69.0 8.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EOO00517.1 - 0.067 11.5 15.8 0.24 9.7 0.1 2.3 2 1 0 2 2 2 0 MFS/sugar transport protein DUF2434 PF10361.4 EOO00519.1 - 3e-122 407.3 8.2 4.3e-122 406.8 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Exo_endo_phos_2 PF14529.1 EOO00520.1 - 0.067 12.8 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Transp_cyt_pur PF02133.10 EOO00521.1 - 1.6e-24 86.3 0.8 1.8e-24 86.1 0.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pmp3 PF01679.12 EOO00521.1 - 1.7 8.3 7.0 0.52 10.0 1.2 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Epimerase PF01370.16 EOO00522.1 - 1.3e-15 57.5 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO00522.1 - 7e-11 41.3 0.1 1e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EOO00522.1 - 1.2e-08 35.1 0.1 1.4e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EOO00522.1 - 2.8e-07 29.7 0.0 8.9e-06 24.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EOO00522.1 - 1.2e-06 28.0 0.2 1.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EOO00522.1 - 1.7e-06 27.8 0.1 8e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EOO00522.1 - 2.1e-05 24.4 0.4 7.3e-05 22.7 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EOO00522.1 - 0.0029 16.6 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EOO00522.1 - 0.0046 15.9 0.2 0.009 14.9 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF3735 PF12537.3 EOO00523.1 - 0.096 12.7 0.1 0.18 11.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) CMD PF02627.15 EOO00525.1 - 5.1e-19 67.8 0.1 1.1e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family 5_nucleotid_C PF02872.13 EOO00526.1 - 2.5e-34 118.5 0.0 5.2e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EOO00526.1 - 9.3e-10 38.2 0.9 7.9e-08 31.9 0.6 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4085 PF13315.1 EOO00527.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Fasciclin PF02469.17 EOO00528.1 - 7.4e-35 119.7 1.4 7.2e-23 80.9 0.3 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF1445 PF07286.7 EOO00528.1 - 0.11 12.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) Melibiase PF02065.13 EOO00530.1 - 3.2e-06 26.0 0.4 5.9e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Melibiase ketoacyl-synt PF00109.21 EOO00531.1 - 1.7e-34 119.4 0.0 2.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EOO00531.1 - 5.5e-14 52.0 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain p450 PF00067.17 EOO00532.1 - 2.3e-28 98.9 0.0 3.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PepX_C PF08530.5 EOO00532.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Nucleoplasmin PF03066.10 EOO00533.1 - 0.053 13.0 5.4 0.061 12.8 2.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin Voldacs PF03517.8 EOO00533.1 - 0.69 9.7 4.0 0.4 10.5 1.4 1.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF2457 PF10446.4 EOO00533.1 - 2 7.0 7.6 3.6 6.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EOO00533.1 - 3.6 7.9 10.5 4.7 7.5 4.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Epimerase PF01370.16 EOO00534.1 - 0.046 13.1 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family COG5 PF10392.4 EOO00535.1 - 3.5e-40 137.0 0.2 9.4e-40 135.6 0.0 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Methyltransf_11 PF08241.7 EOO00536.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO00536.1 - 0.00032 20.4 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00536.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO00536.1 - 0.004 16.2 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EOO00536.1 - 0.0044 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00536.1 - 0.0076 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WW PF00397.21 EOO00537.1 - 1.7e-09 37.3 1.2 3.1e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 WW domain PhoD PF09423.5 EOO00537.1 - 0.00085 18.0 0.1 0.006 15.2 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Velvet PF11754.3 EOO00539.1 - 6.2e-73 244.7 0.0 9.5e-73 244.1 0.0 1.2 1 0 0 1 1 1 1 Velvet factor MSC PF09402.5 EOO00540.1 - 9.4e-100 333.5 0.0 1.3e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EOO00540.1 - 1.3e-16 59.8 0.2 2.9e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.6 EOO00540.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein PMM PF03332.8 EOO00541.1 - 1.2e-98 329.0 0.1 1.6e-98 328.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EOO00541.1 - 0.0068 16.0 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EOO00541.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Chordopox_G3 PF06129.7 EOO00542.1 - 4 7.6 0.1 13 5.9 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus G3 protein NVEALA PF14055.1 EOO00542.1 - 6 6.6 0.2 16 5.3 0.1 1.6 1 0 0 1 1 1 0 NVEALA protein RVT_1 PF00078.22 EOO00543.1 - 7.8e-18 64.6 0.3 7.3e-17 61.4 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.19 EOO00544.1 - 2.3e-54 184.6 10.1 1.1e-42 146.2 1.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00544.1 - 1.1e-09 37.5 5.3 1.4e-09 37.1 3.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EOO00545.1 - 4.3e-14 52.0 5.8 8.1e-14 51.0 1.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00545.1 - 0.00022 19.9 5.7 0.00032 19.4 4.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Transgly_assoc PF04226.8 EOO00545.1 - 0.033 14.2 0.2 2.6 8.2 0.4 2.6 2 0 0 2 2 2 0 Transglycosylase associated protein Cytochrom_B561 PF03188.11 EOO00545.1 - 1.3 8.8 9.4 0.55 10.0 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 ATG22 PF11700.3 EOO00545.1 - 1.7 7.0 11.5 33 2.7 6.4 2.8 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like SieB PF14163.1 EOO00545.1 - 1.9 8.0 0.0 1.9 8.0 0.0 2.6 4 0 0 4 4 4 0 Superinfection exclusion protein B DUF3602 PF12223.3 EOO00546.1 - 7.7e-17 61.4 13.0 6.3e-13 48.9 1.0 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Sulfatase PF00884.18 EOO00547.1 - 3.2e-16 59.4 0.0 5.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EOO00547.1 - 0.0003 19.3 0.0 0.0003 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Helicase_C PF00271.26 EOO00548.1 - 3.1e-20 71.7 0.1 7.5e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO00548.1 - 4.2e-05 23.4 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EOO00548.1 - 0.00042 19.8 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Nucleo_P87 PF07267.6 EOO00548.1 - 1.3 7.6 5.5 2.6 6.6 3.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3605 PF12239.3 EOO00549.1 - 1.2e-54 184.4 3.1 1.4e-54 184.1 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MBOAT_2 PF13813.1 EOO00550.1 - 1.8e-13 50.3 2.0 1.8e-13 50.3 1.4 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Glyco_hydro_7 PF00840.15 EOO00551.1 - 4.5e-201 667.8 21.4 5.2e-201 667.6 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Hist_deacetyl PF00850.14 EOO00552.1 - 1.8e-76 257.3 0.0 2.7e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Herpes_gE PF02480.11 EOO00553.1 - 0.00064 18.0 1.1 0.0027 16.0 0.0 2.1 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 EOO00553.1 - 0.0034 16.6 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2668 PF10873.3 EOO00553.1 - 0.0084 16.2 0.8 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) DAP10 PF07213.6 EOO00553.1 - 0.03 14.0 0.3 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.1 EOO00553.1 - 0.037 13.7 0.7 0.037 13.7 0.5 1.8 2 1 0 2 2 2 0 TMEM154 protein family Cytomega_TRL10 PF06084.6 EOO00553.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein EphA2_TM PF14575.1 EOO00553.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RhoGEF PF00621.15 EOO00554.1 - 6.1e-35 120.7 0.5 1.9e-34 119.1 0.0 2.1 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EOO00554.1 - 1.7e-10 40.8 1.2 5e-10 39.2 0.1 2.3 3 0 0 3 3 3 1 BAR domain DUF1054 PF06335.7 EOO00554.1 - 0.067 12.8 0.6 4.5 6.8 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1054) Seryl_tRNA_N PF02403.17 EOO00554.1 - 0.55 10.2 4.4 3.3 7.7 0.5 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FR47 PF08445.5 EOO00555.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.11 EOO00556.1 - 2.3e-15 56.1 34.5 5.5e-13 48.3 9.6 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 EOO00557.1 - 5.1e-48 162.5 0.2 6.6e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EOO00557.1 - 2.1e-05 24.4 0.1 4.5e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 EOO00557.1 - 0.0038 17.3 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.17 EOO00557.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold URO-D PF01208.12 EOO00558.1 - 7e-123 409.9 0.0 8e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF1664 PF07889.7 EOO00558.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sugar_tr PF00083.19 EOO00559.1 - 1.2e-47 162.6 18.3 9.8e-45 152.9 11.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Epimerase_Csub PF13950.1 EOO00559.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit zf-LITAF-like PF10601.4 EOO00559.1 - 0.34 10.7 2.3 0.31 10.9 0.2 2.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain HLH PF00010.21 EOO00560.1 - 3.1e-18 65.2 0.1 6.9e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMF_DNA_bd PF12329.3 EOO00560.1 - 6.2 6.7 15.2 0.53 10.1 2.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ING PF12998.2 EOO00561.1 - 2.3e-22 79.2 2.8 3.4e-22 78.6 2.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EOO00561.1 - 2.3e-08 33.6 8.6 4.6e-08 32.6 5.9 1.5 1 0 0 1 1 1 1 PHD-finger MFS_1 PF07690.11 EOO00562.1 - 2e-18 66.2 9.9 2e-18 66.2 6.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00562.1 - 2.2e-05 23.2 1.0 2.2e-05 23.2 0.7 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter Sigma_reg_N PF13800.1 EOO00562.1 - 3.4 7.7 6.4 9.9 6.2 0.3 3.3 4 0 0 4 4 4 0 Sigma factor regulator N-terminal AAA_22 PF13401.1 EOO00563.1 - 1.7e-06 28.1 0.6 2e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EOO00563.1 - 9.9e-05 22.5 0.1 0.00031 20.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EOO00563.1 - 0.00028 20.5 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal Arrestin_N PF00339.24 EOO00564.1 - 1.4e-11 44.3 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.13 EOO00565.1 - 8e-10 38.0 0.0 1.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO00565.1 - 3.8e-08 33.0 8.7 6.5e-08 32.3 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAP_C PF03943.8 EOO00566.1 - 3.6e-10 39.0 0.0 6.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EOO00566.1 - 4e-06 26.3 0.0 0.00043 19.8 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EOO00566.1 - 0.004 17.5 0.0 0.014 15.7 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 EOO00566.1 - 0.0048 16.6 0.6 0.046 13.4 0.1 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EOO00566.1 - 0.017 15.0 0.2 0.25 11.4 0.1 3.0 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.1 EOO00566.1 - 0.095 12.8 0.0 4.3 7.7 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat DUF624 PF04854.9 EOO00567.1 - 0.066 13.0 0.9 0.14 12.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 HSP20 PF00011.16 EOO00568.1 - 1.8e-11 43.8 0.0 2.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF2868 PF11067.3 EOO00568.1 - 0.056 12.5 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Pectate_lyase_3 PF12708.2 EOO00569.1 - 0.012 15.7 2.1 0.035 14.2 0.1 2.2 2 0 0 2 2 2 0 Pectate lyase superfamily protein LptE PF04390.7 EOO00569.1 - 0.028 14.1 0.1 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide-assembly PhyH PF05721.8 EOO00570.1 - 7.7e-22 78.3 0.0 1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DAP_C PF07932.7 EOO00570.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 D-aminopeptidase, domain C DUF1479 PF07350.7 EOO00570.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) HET PF06985.6 EOO00571.1 - 1.1e-29 103.3 0.4 1.7e-29 102.7 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GDI PF00996.13 EOO00571.1 - 0.2 9.9 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Aldo_ket_red PF00248.16 EOO00572.1 - 1.5e-62 211.0 0.0 1.9e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGP PF01704.13 EOO00574.1 - 4.4e-185 615.1 0.4 5.2e-185 614.9 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EOO00574.1 - 0.095 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Pilus assembly protein, PilO ADH_zinc_N PF00107.21 EOO00575.1 - 6.2e-18 64.6 0.1 9.1e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO00575.1 - 3.3e-17 62.2 1.3 4.3e-15 55.4 0.9 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO00575.1 - 0.046 14.6 0.0 0.085 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EOO00575.1 - 0.047 13.2 0.4 0.078 12.5 0.3 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FolB PF02152.13 EOO00576.1 - 2.5e-19 69.4 0.0 1.3e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Podoplanin PF05808.6 EOO00577.1 - 0.00054 19.5 0.2 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Podoplanin gpUL132 PF11359.3 EOO00577.1 - 0.0016 17.8 0.2 0.0016 17.8 0.1 2.2 3 0 0 3 3 3 1 Glycoprotein UL132 MtrF PF09472.5 EOO00577.1 - 0.096 11.9 1.3 0.19 11.0 0.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF912 PF06024.7 EOO00577.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PIF1 PF05970.9 EOO00579.1 - 1.5e-21 76.7 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EOO00579.1 - 5.4e-05 22.8 0.0 0.00019 21.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO00579.1 - 0.066 12.9 0.8 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain HA PF03457.9 EOO00579.1 - 0.11 12.6 1.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Helicase associated domain PhyH PF05721.8 EOO00580.1 - 2.4e-07 31.0 0.0 0.00015 21.9 0.0 2.1 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) ABC1 PF03109.11 EOO00584.1 - 6.6e-23 80.9 0.0 6.5e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EOO00584.1 - 0.012 15.3 0.2 0.036 13.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.23 EOO00585.1 - 1.6e-87 294.1 10.4 2e-87 293.8 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tub_2 PF04525.7 EOO00586.1 - 9.4e-23 80.5 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Tubby C 2 FRD2 PF03197.8 EOO00586.1 - 0.12 12.9 0.2 0.34 11.4 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage FRD2 protein COesterase PF00135.23 EOO00587.1 - 7.7e-71 239.3 9.2 1e-50 172.9 0.8 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO00587.1 - 0.0034 17.0 0.2 0.029 13.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4387 PF14330.1 EOO00589.1 - 2.4e-33 114.4 0.0 3.9e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EOO00589.1 - 0.0032 15.9 0.0 0.0054 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) DUF1446 PF07287.6 EOO00590.1 - 3e-38 131.2 0.0 3.5e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Usp PF00582.21 EOO00590.1 - 0.037 14.2 0.1 0.096 12.8 0.0 1.6 1 1 0 1 1 1 0 Universal stress protein family Transp_cyt_pur PF02133.10 EOO00591.1 - 1.6e-94 317.0 37.6 1.9e-94 316.6 26.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AIM24 PF01987.12 EOO00593.1 - 1.2e-35 122.9 0.0 1.6e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Abhydrolase_6 PF12697.2 EOO00594.1 - 3.6e-18 66.2 0.0 4.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO00594.1 - 5.8e-07 29.3 0.0 1.9e-06 27.6 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00594.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold SGL PF08450.7 EOO00595.1 - 6.2e-60 202.6 0.0 7.6e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EOO00595.1 - 0.0077 16.1 0.0 0.047 13.6 0.0 2.3 2 0 0 2 2 2 1 NHL repeat Arylesterase PF01731.15 EOO00595.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Arylesterase PD40 PF07676.7 EOO00595.1 - 0.1 12.2 0.3 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Str_synth PF03088.11 EOO00595.1 - 0.15 12.1 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 Strictosidine synthase Reg_prop PF07494.6 EOO00595.1 - 2.9 8.2 5.9 2.3 8.5 0.0 3.5 4 0 0 4 4 4 0 Two component regulator propeller Glyco_hydro_2_N PF02837.13 EOO00596.1 - 1.7e-07 30.9 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EOO00596.1 - 4.4e-07 30.3 0.0 1.3e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EOO00596.1 - 9.4e-05 21.4 0.1 0.00025 20.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain TRI12 PF06609.8 EOO00597.1 - 1.1e-09 37.1 3.6 1.3e-09 36.8 2.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3100 PF11299.3 EOO00597.1 - 0.35 10.0 6.6 0.46 9.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) adh_short PF00106.20 EOO00598.1 - 2.9e-22 79.3 1.6 2.7e-21 76.2 0.4 2.1 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00598.1 - 5.9e-13 49.1 0.0 7.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00598.1 - 5.9e-11 42.3 0.1 3.3e-08 33.3 0.0 2.2 1 1 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.10 EOO00598.1 - 1.2e-07 30.9 0.0 1.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EOO00598.1 - 1.9e-06 27.5 0.1 2.2e-05 23.9 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EOO00598.1 - 1.7e-05 24.9 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EOO00598.1 - 0.011 16.1 0.2 0.035 14.5 0.1 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EOO00598.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EOO00598.1 - 0.03 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 EOO00598.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family RmlD_sub_bind PF04321.12 EOO00598.1 - 0.044 12.6 0.0 0.1 11.4 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 EOO00598.1 - 0.076 12.0 0.2 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.16 EOO00598.1 - 0.11 12.3 0.8 0.23 11.2 0.6 1.7 1 1 0 1 1 1 0 ThiF family NmrA PF05368.8 EOO00600.1 - 4.3e-12 45.7 0.0 5.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family AMP-binding PF00501.23 EOO00601.1 - 0 2222.4 14.1 6.8e-90 301.4 0.0 8.3 8 0 0 8 8 8 8 AMP-binding enzyme Condensation PF00668.15 EOO00601.1 - 0 1613.6 0.0 7.3e-49 166.2 0.0 14.5 12 4 0 12 12 12 12 Condensation domain PP-binding PF00550.20 EOO00601.1 - 4.8e-76 250.9 5.6 4.8e-10 39.5 0.0 9.0 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EOO00601.1 - 1.4e-36 125.2 4.4 0.00015 22.6 0.0 9.7 8 0 0 8 8 8 8 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EOO00601.1 - 8e-15 54.9 0.0 0.0031 17.8 0.0 5.8 6 0 0 6 6 6 4 HxxPF-repeated domain DUF2400 PF09674.5 EOO00601.1 - 2.3 7.8 5.8 43 3.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2400) TRI5 PF06330.6 EOO00601.1 - 5.1 5.6 0.0 9.2 4.7 0.0 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) NETI PF14044.1 EOO00601.1 - 8.6 5.9 0.1 24 4.5 0.1 1.8 1 0 0 1 1 1 0 NETI protein DUF2757 PF10955.3 EOO00601.1 - 9.4 6.5 0.0 1.2e+02 3.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) FMN_dh PF01070.13 EOO00602.1 - 1.4e-89 300.4 1.8 2.5e-86 289.7 1.2 2.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EOO00602.1 - 8.3e-06 24.9 0.1 1.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EOO00602.1 - 4e-05 22.6 0.1 0.0018 17.2 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EOO00602.1 - 0.044 12.8 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG AMP-binding PF00501.23 EOO00603.1 - 0 1877.7 19.5 6.5e-91 304.7 0.1 8.9 8 1 1 9 9 9 8 AMP-binding enzyme Condensation PF00668.15 EOO00603.1 - 0 1410.0 10.9 1.3e-49 168.7 0.0 10.9 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EOO00603.1 - 5e-71 234.9 18.1 5e-10 39.4 0.0 8.7 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EOO00603.1 - 1.2e-22 80.6 6.5 0.0048 17.8 0.4 8.2 7 0 0 7 7 7 6 AMP-binding enzyme C-terminal domain AATase PF07247.7 EOO00603.1 - 0.0022 16.5 0.2 12 4.2 0.0 6.5 9 0 0 9 9 9 1 Alcohol acetyltransferase Transferase PF02458.10 EOO00603.1 - 0.0063 15.0 0.0 3.1 6.1 0.0 3.3 3 0 0 3 3 3 1 Transferase family DUF2757 PF10955.3 EOO00603.1 - 0.034 14.3 0.0 0.39 10.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) GCS PF03074.11 EOO00603.1 - 4 6.3 0.0 7.7 5.4 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase AMP-binding PF00501.23 EOO00604.1 - 0 1729.1 9.6 1.4e-88 297.1 0.0 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 EOO00604.1 - 0 1308.6 0.0 4e-49 167.0 0.0 12.7 11 2 0 11 11 11 11 Condensation domain PP-binding PF00550.20 EOO00604.1 - 4.3e-54 180.6 10.0 3.9e-08 33.4 0.1 7.3 6 0 0 6 6 6 6 Phosphopantetheine attachment site FAST_1 PF06743.10 EOO00604.1 - 1.3 8.7 0.0 32 4.3 0.0 2.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 AATase PF07247.7 EOO00604.1 - 6.9 5.0 0.0 1.6e+02 0.5 0.0 2.9 4 0 0 4 4 4 0 Alcohol acetyltransferase Dynamin_M PF01031.15 EOO00605.1 - 1.4e-16 60.1 0.6 4.4e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EOO00605.1 - 4.1e-14 52.7 0.0 9.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Apolipoprotein PF01442.13 EOO00605.1 - 0.018 14.5 3.6 0.11 11.9 0.2 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain ABC_membrane PF00664.18 EOO00606.1 - 7.4e-37 127.2 12.2 1e-36 126.8 8.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EOO00606.1 - 1.9e-34 118.8 0.0 7.3e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EOO00606.1 - 4.2e-08 33.5 0.2 2.5e-05 24.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO00606.1 - 1.5e-06 28.2 0.2 7.5e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EOO00606.1 - 6.6e-06 25.5 0.0 0.0026 17.0 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 EOO00606.1 - 8.2e-05 22.5 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EOO00606.1 - 0.00011 23.0 0.0 0.00024 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EOO00606.1 - 0.00024 21.2 0.0 0.0032 17.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EOO00606.1 - 0.00054 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EOO00606.1 - 0.003 17.0 0.0 0.009 15.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EOO00606.1 - 0.0033 16.8 0.0 0.0096 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EOO00606.1 - 0.0044 16.7 0.1 0.038 13.6 0.0 2.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EOO00606.1 - 0.0051 17.1 0.0 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EOO00606.1 - 0.0068 16.3 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EOO00606.1 - 0.0075 16.2 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EOO00606.1 - 0.016 14.3 0.0 0.049 12.7 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EOO00606.1 - 0.016 15.3 0.0 0.14 12.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EOO00606.1 - 0.018 14.9 0.0 0.064 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EOO00606.1 - 0.021 14.3 0.0 0.058 12.8 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 EOO00606.1 - 0.028 14.3 0.4 0.29 11.0 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EOO00606.1 - 0.03 14.0 0.1 0.26 10.9 0.0 2.5 3 0 0 3 3 2 0 NACHT domain AAA_25 PF13481.1 EOO00606.1 - 0.05 13.0 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EOO00606.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 EOO00606.1 - 0.092 12.3 0.3 1 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EOO00606.1 - 0.14 12.4 0.2 0.33 11.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EOO00606.1 - 0.14 12.3 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Beta_helix PF13229.1 EOO00608.1 - 5.6e-09 35.9 24.4 0.00016 21.4 16.9 3.8 1 1 0 1 1 1 1 Right handed beta helix region Dynamin_N PF00350.18 EOO00609.1 - 5.1e-29 101.2 0.1 9.3e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EOO00609.1 - 2.6e-17 62.5 0.3 1.1e-16 60.5 0.0 2.2 4 0 0 4 4 4 1 Dynamin central region MMR_HSR1 PF01926.18 EOO00609.1 - 6.4e-08 32.5 0.1 3.6e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EOO00609.1 - 0.0011 18.2 0.0 0.079 12.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.1 EOO00609.1 - 0.0048 16.9 0.0 0.043 13.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EOO00609.1 - 0.0061 17.0 0.1 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EOO00609.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1045 PF06299.7 EOO00609.1 - 0.026 14.2 0.0 0.17 11.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) ABC_tran PF00005.22 EOO00609.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter VCBS PF13517.1 EOO00610.1 - 6.6e-32 109.6 49.6 1.5e-10 41.2 1.3 8.7 3 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO00610.1 - 1.1e-12 47.2 54.0 0.00036 20.1 0.2 9.3 8 0 0 8 8 8 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EOO00610.1 - 1e-10 41.3 8.3 0.06 12.7 0.0 6.4 5 1 1 6 6 6 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 EOO00610.1 - 4.6e-10 39.9 0.1 2.4e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO00610.1 - 0.00086 19.1 0.0 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Kinesin PF00225.18 EOO00611.1 - 0.00018 20.3 0.0 0.0002 20.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AA_permease PF00324.16 EOO00612.1 - 1.6e-102 343.2 37.0 2e-102 343.0 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO00612.1 - 4.7e-25 88.0 40.2 6.1e-25 87.6 27.9 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EOO00613.1 - 2.9e-29 101.8 56.3 6.9e-20 71.0 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO00613.1 - 3.6e-14 52.0 11.0 3.6e-14 52.0 7.6 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EOO00613.1 - 5.4e-06 25.2 43.6 0.00036 19.2 4.7 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EOO00613.1 - 0.071 12.9 5.8 0.049 13.4 1.7 2.6 2 0 0 2 2 2 0 MFS_1 like family Kinesin PF00225.18 EOO00614.1 - 3.6e-56 190.2 0.1 5e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 EOO00614.1 - 0.00097 19.0 0.0 0.0048 16.8 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif Aminotran_5 PF00266.14 EOO00615.1 - 1.5e-13 50.2 0.0 1.3e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EOO00615.1 - 1.6e-05 23.4 0.0 3.5e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EOO00615.1 - 0.0024 16.9 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L32e PF01655.13 EOO00616.1 - 2.8e-49 165.7 1.7 2.8e-49 165.7 1.2 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 Oxidored_FMN PF00724.15 EOO00617.1 - 9.5e-45 153.0 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_10 PF00331.15 EOO00618.1 - 2e-80 270.2 0.1 2.4e-80 269.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Botulinum_HA-17 PF05588.6 EOO00618.1 - 1.2 9.0 4.5 2.1 8.2 0.4 2.4 1 1 1 2 2 2 0 Clostridium botulinum HA-17 protein Aldedh PF00171.17 EOO00619.1 - 1.7e-179 597.0 0.8 2.1e-179 596.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.24 EOO00620.1 - 9.4e-46 155.3 0.0 2e-44 151.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO00620.1 - 1.2e-28 98.7 0.0 2.6e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO00620.1 - 3e-05 23.9 0.0 0.00019 21.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GRP PF07172.6 EOO00620.1 - 0.00066 20.1 3.8 0.00066 20.1 2.6 3.4 2 1 1 3 3 3 1 Glycine rich protein family DUF1253 PF06862.7 EOO00620.1 - 0.0038 15.6 0.0 0.29 9.4 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EOO00620.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 EOO00620.1 - 0.083 12.6 0.3 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Ribosomal_L30_N PF08079.7 EOO00621.1 - 1e-25 89.4 18.9 1.8e-25 88.7 13.1 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EOO00621.1 - 3.6e-18 64.8 1.6 3.6e-18 64.8 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Clathrin_lg_ch PF01086.12 EOO00621.1 - 0.097 12.5 4.2 0.13 12.1 2.9 1.1 1 0 0 1 1 1 0 Clathrin light chain SIN1 PF05422.7 EOO00622.1 - 1e-42 146.3 1.3 1.9e-19 69.6 0.0 3.2 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EOO00622.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG GTP_cyclohydro2 PF00925.15 EOO00622.1 - 0.087 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Bys1 PF04681.7 EOO00625.1 - 6.6e-14 51.9 1.9 7.8e-14 51.6 1.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Cellulase PF00150.13 EOO00626.1 - 1.1e-56 192.1 1.1 1.3e-56 191.8 0.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arrestin_C PF02752.17 EOO00627.1 - 4e-13 49.6 0.0 1.1e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EOO00627.1 - 3.6e-05 23.6 0.1 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SNF2_N PF00176.18 EOO00628.1 - 2.3e-71 240.0 0.2 3.6e-71 239.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EOO00628.1 - 5.6e-17 61.3 0.0 1.6e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EOO00628.1 - 5.9e-06 25.3 0.0 1.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.1 EOO00628.1 - 0.0012 18.4 0.6 0.04 13.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain Chitin_bind_3 PF03067.10 EOO00629.1 - 6.5e-06 26.5 0.1 2.2e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Chitin binding domain MFS_1 PF07690.11 EOO00630.1 - 2.5e-30 105.3 15.9 2.5e-30 105.3 11.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00630.1 - 2.9e-06 26.1 14.0 7.1e-06 24.8 9.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EOO00630.1 - 0.036 12.1 1.7 0.04 11.9 0.5 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cation_efflux PF01545.16 EOO00630.1 - 0.084 11.9 0.9 0.14 11.1 0.6 1.3 1 0 0 1 1 1 0 Cation efflux family JAB PF01398.16 EOO00631.1 - 1.6e-28 98.6 0.0 2.6e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EOO00631.1 - 9.4e-06 25.1 0.0 2.2e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF883 PF05957.8 EOO00632.1 - 0.047 14.0 1.6 11 6.4 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_S11 PF00411.14 EOO00634.1 - 1.1e-40 138.2 0.4 1.4e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EOO00634.1 - 0.054 12.4 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) LMBR1 PF04791.11 EOO00635.1 - 1.7e-27 96.1 3.0 2.6e-23 82.3 0.1 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein Sugar_tr PF00083.19 EOO00636.1 - 3.8e-86 289.4 20.4 4.4e-86 289.2 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00636.1 - 1e-20 73.7 45.6 3.9e-15 55.4 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos_2 PF12850.2 EOO00636.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1228 PF06779.9 EOO00636.1 - 0.14 12.2 6.7 1.5 8.9 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) OATP PF03137.15 EOO00636.1 - 0.94 7.4 9.0 1.3 6.9 0.0 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ricin_B_lectin PF00652.17 EOO00637.1 - 8.8e-07 28.9 0.0 0.0034 17.4 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Imm15 PF15590.1 EOO00637.1 - 0.046 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 15 F-box-like PF12937.2 EOO00638.1 - 0.0094 15.6 1.7 0.0094 15.6 1.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EOO00638.1 - 0.012 15.3 5.6 0.65 9.7 0.3 3.9 2 1 1 3 3 3 0 Leucine rich repeat Lac_bphage_repr PF06543.7 EOO00638.1 - 0.013 15.0 0.0 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor LRR_4 PF12799.2 EOO00638.1 - 0.031 13.9 10.0 0.76 9.4 0.1 4.7 3 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EOO00638.1 - 8.4 6.8 11.9 36 4.8 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat Sulfotransfer_3 PF13469.1 EOO00639.1 - 0.036 15.0 0.1 0.049 14.5 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase family CorA PF01544.13 EOO00640.1 - 5.4e-21 74.8 4.0 7.1e-18 64.6 0.7 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 EOO00641.1 - 4.4e-21 74.3 9.5 2.1e-11 43.3 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EOO00641.1 - 9.1e-17 59.8 6.7 1.4e-08 33.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EOO00641.1 - 1e-15 56.3 7.5 1.8e-06 27.3 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EOO00641.1 - 1.6e-12 46.2 3.0 3.2e-05 23.3 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EOO00641.1 - 7.1e-10 38.6 0.9 3.5e-06 26.8 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EOO00641.1 - 2.6e-09 36.1 0.3 5.8e-07 28.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EOO00641.1 - 4.8e-09 36.0 0.4 0.13 12.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 EOO00641.1 - 1.4e-07 31.0 0.3 2.8e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 EOO00641.1 - 5.8e-07 29.2 0.1 0.0048 16.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00641.1 - 3.2e-05 24.4 1.0 0.0014 19.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EOO00641.1 - 4.8e-05 23.1 0.3 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EOO00641.1 - 9.5e-05 22.7 0.3 0.022 15.3 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EOO00641.1 - 0.016 15.3 2.8 0.019 15.1 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 EOO00641.1 - 0.054 12.0 0.1 0.098 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EOO00641.1 - 0.062 13.6 0.3 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EOO00641.1 - 0.067 13.1 0.2 5.7 7.0 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EOO00641.1 - 0.081 13.4 0.1 37 5.1 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Apc5 PF12862.2 EOO00641.1 - 0.13 12.1 0.1 0.37 10.6 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 RICTOR_N PF14664.1 EOO00642.1 - 6.3e-97 324.4 1.7 1.5e-95 319.9 0.6 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EOO00642.1 - 1.3e-89 299.1 0.2 2.9e-88 294.6 0.0 3.1 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EOO00642.1 - 4.1e-37 126.6 0.0 2.2e-35 121.0 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EOO00642.1 - 1.3e-27 95.5 0.3 1.2e-26 92.3 0.1 2.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EOO00642.1 - 2.1e-14 52.9 6.1 4.8e-14 51.8 4.2 1.7 1 0 0 1 1 1 1 Hr1 repeat Pol_alpha_B_N PF08418.5 EOO00642.1 - 0.022 14.3 1.3 0.041 13.4 0.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal IncA PF04156.9 EOO00642.1 - 0.041 13.4 4.3 0.089 12.3 3.0 1.5 1 0 0 1 1 1 0 IncA protein M_domain PF12938.2 EOO00642.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 M domain of GW182 Uds1 PF15456.1 EOO00642.1 - 0.54 10.2 11.4 0.015 15.3 3.2 1.9 2 0 0 2 2 2 0 Up-regulated During Septation APC_CDC26 PF10471.4 EOO00643.1 - 0.028 15.1 2.5 0.06 14.0 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 POM121 PF15229.1 EOO00643.1 - 0.49 9.7 7.2 0.63 9.4 5.0 1.1 1 0 0 1 1 1 0 POM121 family DUF3043 PF11241.3 EOO00643.1 - 2.5 7.6 5.2 3.2 7.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) NARP1 PF12569.3 EOO00643.1 - 4 6.0 6.0 4.9 5.7 4.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L13 PF00572.13 EOO00645.1 - 4.2e-37 127.0 0.0 5.7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 MFS_1 PF07690.11 EOO00646.1 - 1.7e-14 53.2 18.3 5.7e-14 51.6 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00646.1 - 3.1e-08 32.6 7.7 5.1e-08 31.9 5.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PAP2 PF01569.16 EOO00646.1 - 0.0064 16.1 6.4 0.0064 16.1 4.4 2.3 2 2 0 2 2 2 1 PAP2 superfamily S1FA PF04689.8 EOO00646.1 - 0.012 15.4 1.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 0 DNA binding protein S1FA SR-25 PF10500.4 EOO00646.1 - 0.023 14.1 7.1 0.036 13.5 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GSG-1 PF07803.6 EOO00647.1 - 0.32 10.6 2.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 GSG1-like protein RRM_1 PF00076.17 EOO00648.1 - 1e-16 60.3 0.0 1.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00648.1 - 3e-12 46.3 0.0 4.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO00648.1 - 2.5e-10 40.0 0.1 4.6e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EOO00648.1 - 0.014 15.1 0.1 0.046 13.4 0.0 1.9 1 1 1 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.1 EOO00648.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PDH PF02153.12 EOO00649.1 - 2e-13 49.8 0.0 3.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Polysacc_deac_1 PF01522.16 EOO00650.1 - 7.7e-28 96.6 0.0 1.4e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EOO00650.1 - 2.1e-10 40.4 51.0 4.9e-05 23.2 15.2 3.0 2 0 0 2 2 2 2 Chitin recognition protein Rad9 PF04139.8 EOO00651.1 - 2.1e-11 43.4 0.0 2.4e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Rad9 Flavi_glycoprot PF00869.15 EOO00651.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains Fib_alpha PF08702.5 EOO00652.1 - 0.19 11.8 3.5 0.32 11.0 2.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CAML PF14963.1 EOO00653.1 - 6.6 6.0 9.6 11 5.3 6.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Uricase PF01014.13 EOO00654.1 - 2e-86 287.0 0.4 3e-47 160.1 0.5 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EOO00654.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme AAR2 PF05282.6 EOO00655.1 - 8.7e-47 159.7 0.0 2.2e-45 155.1 0.0 2.4 1 1 0 1 1 1 1 AAR2 protein DUF4604 PF15377.1 EOO00655.1 - 0.28 11.3 0.9 0.56 10.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Phos_pyr_kin PF08543.7 EOO00656.1 - 2.8e-86 288.7 0.6 7.3e-86 287.3 0.6 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EOO00656.1 - 3.5e-45 154.3 0.0 4.9e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EOO00656.1 - 1.7e-07 30.6 0.3 2.7e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EOO00656.1 - 0.067 12.3 2.3 1.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family DnaJ PF00226.26 EOO00657.1 - 5e-23 80.6 3.1 1.4e-22 79.2 2.1 1.8 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EOO00657.1 - 8.3e-19 67.2 0.1 1.1e-16 60.5 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EOO00657.1 - 7.9e-14 51.4 15.8 1.3e-13 50.8 11.0 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EOO00657.1 - 0.003 17.2 7.2 0.19 11.4 0.5 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family UreE_N PF02814.10 EOO00657.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain DZR PF12773.2 EOO00657.1 - 1.4 8.8 9.4 4.8 7.0 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EOO00657.1 - 1.5 9.0 7.1 1.2 9.3 0.6 2.4 2 0 0 2 2 2 0 CHY zinc finger Ribosomal_S9 PF00380.14 EOO00659.1 - 7.3e-39 132.7 0.1 8.2e-39 132.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EOO00659.1 - 0.028 11.9 0.0 0.033 11.6 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein PAN_1 PF00024.21 EOO00661.1 - 6.1e-05 22.7 0.2 6.1e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 PAN domain DUF3311 PF11755.3 EOO00661.1 - 0.0093 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) PAN_4 PF14295.1 EOO00661.1 - 0.076 12.7 0.7 0.4 10.4 0.5 2.1 1 1 0 1 1 1 0 PAN domain Macoilin PF09726.4 EOO00661.1 - 5 5.2 6.1 5.6 5.1 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SGL PF08450.7 EOO00662.1 - 4.7e-69 232.4 0.0 6.7e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EOO00662.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase TFIIIC_delta PF12657.2 EOO00662.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term HemolysinCabind PF00353.14 EOO00662.1 - 0.15 12.4 1.2 0.68 10.4 0.8 2.2 1 0 0 1 1 1 0 Hemolysin-type calcium-binding repeat (2 copies) Mpv17_PMP22 PF04117.7 EOO00663.1 - 2.1e-12 46.4 3.0 4.2e-11 42.3 1.6 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family ELFV_dehydrog PF00208.16 EOO00664.1 - 3.3e-60 203.7 0.0 5.5e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EOO00664.1 - 4.6e-19 67.4 0.0 6.6e-14 50.3 0.0 2.5 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EOO00664.1 - 0.00045 19.7 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PRCC PF10253.4 EOO00665.1 - 3.3e-36 125.6 0.3 3.3e-36 125.6 0.2 2.2 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Alk_phosphatase PF00245.15 EOO00666.1 - 1.7e-104 349.8 0.0 2e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EOO00666.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily p450 PF00067.17 EOO00667.1 - 8.3e-44 149.8 0.0 1.1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NPV_P10 PF05531.7 EOO00667.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Methyltransf_PK PF05891.7 EOO00668.1 - 9.3e-85 283.3 0.0 1e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EOO00668.1 - 0.00021 21.0 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO00668.1 - 0.0014 19.1 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EOO00668.1 - 0.0079 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EOO00668.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.1 EOO00669.1 - 3e-26 92.6 0.0 3.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO00669.1 - 1.4e-21 77.1 4.8 1.9e-21 76.7 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00669.1 - 2.8e-13 49.9 1.3 3.6e-13 49.5 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO00669.1 - 0.00026 20.5 0.1 0.00033 20.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO00669.1 - 0.0041 15.8 0.0 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EOO00669.1 - 0.0063 15.4 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GRP PF07172.6 EOO00670.1 - 0.016 15.6 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family LigD_N PF13298.1 EOO00671.1 - 1.1e-19 70.4 0.0 5e-19 68.3 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase Ligase (LigD) EF-hand_1 PF00036.27 EOO00672.1 - 4.3e-38 125.7 10.5 1.1e-08 33.8 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EOO00672.1 - 1.6e-32 111.4 3.3 6.3e-17 61.4 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EOO00672.1 - 1.2e-30 104.8 6.4 9e-15 54.0 0.2 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EOO00672.1 - 1.6e-29 99.0 3.1 3.8e-08 32.5 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EOO00672.1 - 3.2e-25 86.3 5.9 2.9e-07 29.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EOO00672.1 - 2.6e-12 46.4 0.1 4.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EOO00672.1 - 8.7e-09 35.0 1.0 0.00038 20.1 0.1 2.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EOO00672.1 - 5.7e-06 26.3 0.0 0.036 14.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 EOO00672.1 - 0.00081 18.9 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 2 Caleosin related protein TerB PF05099.8 EOO00672.1 - 0.0011 18.7 0.2 0.86 9.3 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EOO00672.1 - 0.0016 18.0 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Tenui_NCP PF04876.7 EOO00672.1 - 0.0068 15.9 0.2 2.9 7.3 0.0 2.6 1 1 1 3 3 3 2 Tenuivirus major non-capsid protein EFhand_Ca_insen PF08726.5 EOO00672.1 - 0.0091 15.9 0.1 0.59 10.1 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 EOO00672.1 - 0.015 15.2 0.1 1.2 9.1 0.0 2.5 2 2 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF892 PF05974.7 EOO00672.1 - 0.04 13.7 0.4 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF892) RNA_pol_Rpb4 PF03874.11 EOO00672.1 - 0.055 13.4 0.4 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 EOO00672.1 - 0.098 12.9 0.3 7.8 6.8 0.1 2.5 1 1 1 2 2 2 0 Toprim-like SpoVIF PF14069.1 EOO00672.1 - 0.15 11.7 0.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F PX PF00787.19 EOO00673.1 - 6.8e-21 74.1 0.0 1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Thioredoxin_4 PF13462.1 EOO00674.1 - 0.00036 20.5 0.0 0.00072 19.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin SAS4 PF15460.1 EOO00675.1 - 4.6e-34 116.3 0.1 4.6e-34 116.3 0.1 2.4 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.7 EOO00675.1 - 0.031 12.2 34.2 0.048 11.5 23.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EOO00675.1 - 1.1 8.6 21.9 2.4 7.4 15.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 EOO00675.1 - 1.2 7.5 31.4 3 6.2 21.8 1.6 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EOO00675.1 - 3.8 5.1 12.8 7 4.2 8.9 1.4 1 0 0 1 1 1 0 Ycf1 AA_permease_2 PF13520.1 EOO00676.1 - 1.9e-41 142.0 47.7 2.3e-41 141.7 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO00676.1 - 7.4e-27 93.8 40.9 1e-26 93.3 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.9 EOO00677.1 - 4.2e-06 26.7 0.8 3.3e-05 23.8 0.2 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO00677.1 - 5.5e-05 22.2 0.2 0.0034 16.3 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EOO00677.1 - 6.3e-05 22.8 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EOO00677.1 - 0.00071 18.3 0.1 0.0015 17.2 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EOO00677.1 - 0.0045 16.9 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EOO00677.1 - 0.0078 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EOO00677.1 - 0.012 15.7 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO00677.1 - 0.057 13.8 0.2 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EOO00677.1 - 0.21 10.4 0.3 0.92 8.2 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Rad4 PF03835.10 EOO00678.1 - 1.7e-15 56.7 5.1 3.1e-15 55.8 3.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EOO00678.1 - 0.059 13.5 0.9 0.14 12.3 0.6 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_hydro_3 PF00933.16 EOO00679.1 - 4.1e-82 275.5 0.0 5.8e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO00679.1 - 4.1e-75 252.2 0.0 5.5e-74 248.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO00679.1 - 5.6e-24 83.8 0.1 1.1e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EOO00679.1 - 2.3e-18 66.2 0.0 4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 PA14 domain FAD_binding_3 PF01494.14 EOO00681.1 - 7.5e-22 77.8 1.3 1e-20 74.0 0.9 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO00681.1 - 4.8e-07 29.0 0.5 0.0012 17.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO00681.1 - 0.0025 17.8 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EOO00681.1 - 0.0034 16.5 0.1 1 8.3 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EOO00681.1 - 0.021 13.4 1.0 0.049 12.2 0.3 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Sigma70_r3 PF04539.11 EOO00681.1 - 0.036 13.9 0.3 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 Pyr_redox PF00070.22 EOO00681.1 - 0.079 13.3 0.3 0.41 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO00682.1 - 1.5e-83 280.9 0.8 1.9e-83 280.6 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EOO00682.1 - 3.1e-20 71.7 0.2 2.4e-19 68.9 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EOO00682.1 - 8.3e-13 47.9 2.2 4.5e-12 45.5 1.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EOO00682.1 - 1.8e-09 37.2 0.4 5.6e-09 35.5 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO00682.1 - 1e-08 35.0 0.5 1.1e-07 31.7 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EOO00682.1 - 2.8e-08 33.8 0.0 1.8e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO00682.1 - 1.8e-05 23.4 2.5 0.0044 15.5 0.0 3.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EOO00682.1 - 5.1e-05 22.4 0.4 0.0075 15.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EOO00682.1 - 0.0003 20.0 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 EOO00682.1 - 0.0003 19.7 1.5 0.075 11.8 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EOO00682.1 - 0.0026 16.8 1.4 0.0063 15.6 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EOO00682.1 - 0.033 14.2 0.9 0.081 12.9 0.6 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dimeth_Pyl PF09505.5 EOO00682.1 - 0.069 11.4 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Pyr_redox PF00070.22 EOO00682.1 - 0.76 10.2 4.6 2.2 8.7 1.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YicC_N PF03755.8 EOO00683.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region PALP PF00291.20 EOO00684.1 - 2.8e-58 197.5 1.8 3.2e-58 197.3 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Form-deh_trans PF09163.6 EOO00685.1 - 0.17 11.4 0.8 4.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Vfa1 PF08432.5 EOO00685.1 - 0.35 10.8 3.2 0.55 10.2 2.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med17 PF10156.4 EOO00685.1 - 7.1 4.7 12.1 12 4.0 8.4 1.3 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Rep_4 PF05797.6 EOO00685.1 - 7.6 5.1 8.3 11 4.5 5.7 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) adh_short PF00106.20 EOO00686.1 - 8.4e-25 87.6 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00686.1 - 3e-12 46.8 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00686.1 - 4.4e-09 36.2 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO00686.1 - 1.6e-07 30.5 0.0 2.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EOO00686.1 - 5.7e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EOO00686.1 - 5.3e-05 22.7 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EOO00686.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EOO00686.1 - 0.003 16.3 0.0 0.0042 15.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Oxidored_nitro PF00148.14 EOO00686.1 - 0.017 13.7 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.12 EOO00686.1 - 0.04 14.3 0.0 0.093 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EOO00686.1 - 0.11 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 EOO00686.1 - 0.23 11.2 0.8 0.49 10.2 0.2 1.7 2 0 0 2 2 2 0 ThiF family PetG PF02529.10 EOO00687.1 - 0.18 11.3 1.2 0.52 9.8 0.9 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF1843 PF08898.5 EOO00688.1 - 0.0073 16.3 0.4 0.06 13.3 0.3 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1843) BRI3BP PF14965.1 EOO00688.1 - 0.062 12.6 0.7 0.23 10.7 0.1 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 THP2 PF09432.5 EOO00688.1 - 1.3 8.9 10.9 0.14 12.0 2.3 3.0 1 1 1 2 2 2 0 Tho complex subunit THP2 CENP-K PF11802.3 EOO00688.1 - 7.1 5.7 18.1 39 3.3 1.7 2.3 1 1 1 2 2 2 0 Centromere-associated protein K DUF2935 PF11155.3 EOO00688.1 - 7.2 6.7 9.2 3.1 7.9 1.7 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) GTP_EFTU PF00009.22 EOO00689.1 - 1.5e-42 145.2 0.0 2.1e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EOO00689.1 - 4e-27 94.1 0.0 1.3e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EOO00689.1 - 5.2e-19 67.9 0.0 1.6e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EOO00689.1 - 1.7e-08 34.4 0.0 6.4e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EOO00689.1 - 9e-07 28.6 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EOO00689.1 - 4e-06 26.7 0.2 7.3e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EOO00689.1 - 0.00078 19.9 0.0 0.0025 18.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EOO00689.1 - 0.16 10.5 0.2 0.28 9.8 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MFS_1 PF07690.11 EOO00690.1 - 2.4e-51 174.5 35.1 2.4e-51 174.5 24.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00690.1 - 4.8e-10 38.6 10.5 4.8e-10 38.6 7.3 3.3 2 2 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EOO00690.1 - 5.2e-06 24.9 3.5 8.7e-06 24.2 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2207 PF09972.4 EOO00690.1 - 0.17 10.4 12.2 0.4 9.2 0.0 3.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) DUF2583 PF10762.4 EOO00690.1 - 0.26 11.4 4.0 12 6.0 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) OATP PF03137.15 EOO00690.1 - 0.39 8.7 15.6 0.015 13.3 1.5 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.20 EOO00691.1 - 2.6e-59 200.4 0.0 3.8e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00691.1 - 1.5e-25 89.7 0.0 2.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO00691.1 - 1.1e-07 31.1 0.0 1.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EOO00691.1 - 0.0018 18.0 0.1 0.72 9.5 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EOO00691.1 - 0.0065 15.5 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GDYXXLXY PF14345.1 EOO00691.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 GDYXXLXY protein Choline_kinase PF01633.15 EOO00691.1 - 0.23 10.9 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 EOO00692.1 - 3.3e-47 160.6 0.0 3.8e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fasciclin PF02469.17 EOO00693.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain Ribosomal_L31e PF01198.14 EOO00694.1 - 4e-37 125.7 1.7 5e-37 125.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Peptidase_S8 PF00082.17 EOO00696.1 - 3.8e-53 180.4 1.0 3.8e-53 180.4 0.7 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EOO00696.1 - 2.4e-26 91.3 1.3 5.7e-26 90.1 0.9 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain PepSY_TM_2 PF13703.1 EOO00696.1 - 0.19 11.9 0.9 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix NAD_binding_10 PF13460.1 EOO00697.1 - 6e-18 65.4 0.0 7.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO00697.1 - 3.4e-15 56.1 0.0 5.2e-13 48.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family XhoI PF04555.8 EOO00697.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI MARVEL PF01284.18 EOO00699.1 - 1.9e-10 40.7 17.1 2.7e-10 40.2 11.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2678 PF10856.3 EOO00699.1 - 0.059 13.1 1.0 0.097 12.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) NAD_binding_1 PF00175.16 EOO00701.1 - 6.7e-32 110.2 0.0 2.8e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EOO00701.1 - 6.3e-22 77.5 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EOO00701.1 - 8.5e-09 35.4 0.0 0.00059 19.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EOO00701.1 - 0.00072 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain CsbD PF05532.7 EOO00701.1 - 0.0059 16.2 1.7 0.011 15.4 1.2 1.4 1 0 0 1 1 1 1 CsbD-like DUF4366 PF14283.1 EOO00701.1 - 0.015 14.7 0.2 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Mito_carr PF00153.22 EOO00702.1 - 7.3e-61 201.8 2.8 1.4e-21 76.0 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SR-25 PF10500.4 EOO00703.1 - 0.00012 21.6 11.7 0.00012 21.6 8.1 4.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein IQ PF00612.22 EOO00703.1 - 0.00039 19.8 1.8 0.0012 18.2 1.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif NAPRTase PF04095.11 EOO00704.1 - 6.7e-52 176.2 0.5 1.6e-50 171.6 0.4 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family ABC_trans_N PF14510.1 EOO00704.1 - 0.092 12.8 0.1 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Fungal_trans PF04082.13 EOO00705.1 - 8.7e-10 37.8 0.0 2.9e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO00705.1 - 0.0033 17.2 7.4 0.0055 16.5 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 EOO00708.1 - 2.4e-39 133.8 0.5 5.2e-39 132.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EOO00708.1 - 4.8e-12 45.8 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Fungal_trans PF04082.13 EOO00709.1 - 2.6e-06 26.5 0.0 4.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1631 PF07793.6 EOO00709.1 - 0.075 11.1 1.1 0.082 11.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ADH_zinc_N PF00107.21 EOO00710.1 - 1.5e-25 89.2 0.1 2.9e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO00710.1 - 6e-08 32.4 0.0 2.6e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO00710.1 - 0.014 16.2 0.0 0.035 14.9 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 EOO00710.1 - 0.016 15.1 3.3 0.026 14.5 1.2 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.16 EOO00710.1 - 0.053 13.0 3.1 0.076 12.5 0.8 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.15 EOO00710.1 - 0.06 12.4 0.1 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Eno-Rase_NADH_b PF12242.3 EOO00710.1 - 0.12 12.1 2.9 0.28 10.9 2.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 EOO00711.1 - 2.7e-05 23.8 9.5 5.8 6.9 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF3807 PF12720.2 EOO00712.1 - 9.9e-43 146.2 9.6 1.2e-42 145.9 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 EOO00712.1 - 0.0035 17.3 1.0 0.0042 17.0 0.7 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family YL1 PF05764.8 EOO00712.1 - 0.0078 15.8 7.0 0.0096 15.5 4.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Usp PF00582.21 EOO00712.1 - 0.11 12.6 0.9 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 Universal stress protein family p450 PF00067.17 EOO00713.1 - 1.9e-76 257.4 0.0 2.2e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADK PF00406.17 EOO00714.1 - 1.3e-36 125.7 0.0 6e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EOO00714.1 - 1.1e-14 53.8 0.0 2.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EOO00714.1 - 1.4e-05 25.9 0.0 2.8e-05 24.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EOO00714.1 - 0.00025 21.3 0.0 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EOO00714.1 - 0.00046 20.0 0.0 0.0071 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EOO00714.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EOO00714.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EOO00715.1 - 7.9e-60 202.1 0.1 9.2e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00715.1 - 1.8e-19 69.8 0.0 2.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EOO00715.1 - 2.6e-08 33.8 0.0 5.3e-06 26.3 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EOO00715.1 - 0.0088 15.6 0.1 0.022 14.3 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EOO00715.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EOO00715.1 - 0.062 12.6 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EOO00715.1 - 0.072 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec61_beta PF03911.11 EOO00716.1 - 7.4e-21 73.6 1.5 9.6e-21 73.3 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family Transp_cyt_pur PF02133.10 EOO00717.1 - 2.1e-46 158.4 5.4 2.4e-44 151.5 3.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF681 PF05080.7 EOO00717.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF681) SpoIIP PF07454.6 EOO00719.1 - 0.046 12.8 0.2 0.068 12.3 0.1 1.3 1 1 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3357 PF11837.3 EOO00720.1 - 0.0052 16.6 1.8 0.084 12.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3357) MacB_PCD PF12704.2 EOO00720.1 - 0.049 13.2 0.2 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain Shisa PF13908.1 EOO00720.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.3 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator Raffinose_syn PF05691.7 EOO00721.1 - 2.8e-56 190.5 3.6 1.6e-45 154.9 0.1 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.21 EOO00721.1 - 1.6e-05 23.9 0.6 2.9e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ocr PF08684.5 EOO00721.1 - 0.00094 19.1 0.1 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 1 DNA mimic ocr Melibiase PF02065.13 EOO00721.1 - 0.0023 16.6 1.4 0.004 15.8 0.6 1.5 2 0 0 2 2 2 1 Melibiase Helicase_C PF00271.26 EOO00721.1 - 0.03 14.1 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Ssu72 PF04722.8 EOO00722.1 - 1.8e-74 249.2 0.0 2.1e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NUP PF06516.6 EOO00723.1 - 5e-123 409.9 0.1 5.8e-123 409.7 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ribonuc_L-PSP PF01042.16 EOO00724.1 - 8.2e-19 67.5 0.0 9.2e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AIG2 PF06094.7 EOO00725.1 - 5.8e-08 33.1 0.1 1e-07 32.3 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family SpoIIE PF07228.7 EOO00725.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) F-box-like PF12937.2 EOO00726.1 - 5.1e-11 42.1 0.1 1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EOO00726.1 - 0.00017 21.1 0.0 0.00043 19.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_31 PF01055.21 EOO00727.1 - 1.1e-156 522.0 0.7 1.4e-156 521.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 EOO00727.1 - 0.13 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Spc7 PF08317.6 EOO00728.1 - 2.7e-85 285.9 15.1 3.2e-85 285.6 10.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 EOO00728.1 - 1.2e-05 24.9 12.6 1.2e-05 24.9 8.7 1.7 2 0 0 2 2 2 1 IncA protein DUF4200 PF13863.1 EOO00728.1 - 0.0016 18.3 10.2 0.0036 17.2 7.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DUF812 PF05667.6 EOO00728.1 - 0.0072 14.8 3.9 0.0083 14.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MT PF12777.2 EOO00728.1 - 0.025 13.3 3.0 0.038 12.7 2.1 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Laminin_II PF06009.7 EOO00728.1 - 0.037 13.7 6.0 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II Mnd1 PF03962.10 EOO00728.1 - 0.068 12.8 14.1 0.045 13.4 0.7 2.5 2 1 1 3 3 3 0 Mnd1 family APG6 PF04111.7 EOO00728.1 - 0.079 11.9 10.7 0.017 14.1 5.2 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EOO00728.1 - 0.18 11.9 6.5 0.9 9.7 0.3 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 EOO00728.1 - 0.27 11.0 13.1 0.19 11.4 2.8 3.4 1 1 2 3 3 3 0 Prefoldin subunit AAA_13 PF13166.1 EOO00728.1 - 0.54 8.6 8.9 1.5 7.1 6.2 1.7 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 EOO00728.1 - 0.59 10.0 11.8 0.31 10.9 4.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EOO00728.1 - 0.59 9.9 15.3 0.68 9.7 5.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EOO00728.1 - 1.1 9.1 21.3 1.2 9.0 11.9 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EOO00728.1 - 4.5 6.3 13.9 3.7 6.7 8.5 1.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EOO00728.1 - 4.9 4.8 7.9 2.4 5.8 0.4 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.4 EOO00728.1 - 6.6 6.3 12.6 0.33 10.5 0.6 2.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CDC27 PF09507.5 EOO00729.1 - 0.027 13.6 25.3 0.033 13.4 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pneumo_att_G PF05539.6 EOO00729.1 - 0.065 12.6 31.5 0.095 12.0 21.8 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PepSY_TM_3 PF13706.1 EOO00729.1 - 0.22 10.9 1.3 0.32 10.4 0.9 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Pheromone PF08015.6 EOO00729.1 - 2.9 8.8 13.3 26 5.7 8.9 2.6 1 1 0 1 1 1 0 Fungal mating-type pheromone Menin PF05053.8 EOO00729.1 - 4.3 5.3 15.5 5.8 4.9 10.7 1.2 1 0 0 1 1 1 0 Menin GDPD PF03009.12 EOO00730.1 - 1.7e-12 47.3 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Cep57_MT_bd PF06657.8 EOO00731.1 - 5.8e-24 83.8 0.1 5.8e-24 83.8 0.1 4.7 4 0 0 4 4 4 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EOO00731.1 - 6.9e-11 41.9 7.2 6.9e-11 41.9 5.0 6.6 3 1 3 6 6 6 1 Centrosome localisation domain of PPC89 CCDC155 PF14662.1 EOO00731.1 - 0.0016 18.0 58.5 0.045 13.3 16.6 4.4 2 1 2 4 4 4 3 Coiled-coil region of CCDC155 GAS PF13851.1 EOO00731.1 - 0.12 11.5 48.9 0.069 12.3 10.8 4.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EOO00731.1 - 7.5 6.1 49.1 0.075 12.5 2.3 7.3 4 2 3 7 7 7 0 Septum formation initiator adh_short PF00106.20 EOO00732.1 - 5.8e-26 91.3 0.9 7.4e-26 91.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00732.1 - 2.5e-25 89.6 0.0 3.2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00732.1 - 1.8e-08 34.2 0.1 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO00732.1 - 0.0011 18.4 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ARGLU PF15346.1 EOO00733.1 - 0.53 10.0 15.1 0.16 11.7 7.9 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Cache_2 PF08269.6 EOO00733.1 - 1.5 8.8 5.6 1.3 9.0 1.4 2.5 2 1 0 2 2 2 0 Cache domain CDC37_N PF03234.9 EOO00733.1 - 5 7.4 8.9 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding adh_short PF00106.20 EOO00734.1 - 6.8e-28 97.6 1.5 1e-27 97.1 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00734.1 - 1.4e-25 90.4 0.0 1.7e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00734.1 - 1.7e-10 40.8 0.8 2.9e-10 40.0 0.6 1.3 1 0 0 1 1 1 1 KR domain DUF4448 PF14610.1 EOO00735.1 - 1.8e-44 151.5 0.0 2.5e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EOO00735.1 - 0.077 13.4 5.0 1.1 9.7 0.5 3.1 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PX PF00787.19 EOO00737.1 - 5e-21 74.5 0.1 1.4e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EOO00737.1 - 4.1e-12 45.8 9.2 1.6e-06 27.5 0.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EOO00737.1 - 3.2e-06 26.8 3.8 6.5e-06 25.8 2.2 1.8 2 1 0 2 2 2 1 BAR domain Reo_sigmaC PF04582.7 EOO00737.1 - 0.004 16.3 0.1 0.0067 15.6 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF3140 PF11338.3 EOO00737.1 - 0.0062 16.6 2.5 0.01 15.9 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) FlaC_arch PF05377.6 EOO00737.1 - 0.046 13.6 0.8 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) eIF3_subunit PF08597.5 EOO00737.1 - 0.087 12.3 8.8 0.09 12.3 3.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit IncA PF04156.9 EOO00737.1 - 0.089 12.3 0.1 0.089 12.3 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EOO00737.1 - 1.4 8.7 4.6 9.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCM2_N PF12619.3 EOO00737.1 - 2.6 8.0 11.5 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 Mini-chromosome maintenance protein 2 V_ATPase_I PF01496.14 EOO00737.1 - 4.1 5.1 4.7 12 3.5 0.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sugar_tr PF00083.19 EOO00738.1 - 8.9e-114 380.5 17.3 7.5e-112 374.1 12.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO00738.1 - 2.3e-23 82.4 27.3 8.5e-16 57.5 2.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1708 PF08101.6 EOO00740.1 - 2.5e-156 520.7 0.0 3.3e-156 520.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) p450 PF00067.17 EOO00741.1 - 1.1e-55 188.9 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_2_N PF02837.13 EOO00741.1 - 1.5e-36 125.4 0.2 2.5e-34 118.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EOO00741.1 - 7.5e-31 107.1 0.0 2.2e-30 105.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EOO00741.1 - 2.3e-14 53.7 0.0 5.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EOO00741.1 - 7.6e-06 26.1 2.1 0.00057 20.1 0.1 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cas_NE0113 PF09623.5 EOO00741.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) tRNA-synt_2c PF01411.14 EOO00742.1 - 4.7e-209 695.2 0.0 4.7e-209 695.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EOO00742.1 - 4.3e-17 61.7 0.3 9.9e-17 60.5 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EOO00742.1 - 2.1e-05 24.0 0.9 4.6e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 DHHA1 domain PhaP_Bmeg PF09602.5 EOO00742.1 - 0.19 11.5 4.7 0.17 11.6 1.0 2.4 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PAH PF02671.16 EOO00743.1 - 2e-41 139.3 6.0 5.3e-19 67.5 0.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EOO00743.1 - 7.1e-39 131.6 0.3 3.7e-38 129.3 0.0 2.4 3 0 0 3 3 3 1 Sin3 family co-repressor Peptidase_S8 PF00082.17 EOO00744.1 - 2.6e-48 164.6 4.0 7.3e-48 163.1 1.3 2.3 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EOO00744.1 - 7.4e-06 26.3 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EOO00744.1 - 8.2e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M1 PF01433.15 EOO00745.1 - 2.4e-06 26.9 0.0 0.76 8.8 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 IMPDH PF00478.20 EOO00746.1 - 1.7e-133 444.8 1.8 2.1e-133 444.5 1.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EOO00746.1 - 6.1e-17 61.1 0.1 2.2e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EOO00746.1 - 2.3e-09 36.5 1.4 6.2e-08 31.8 0.4 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EOO00746.1 - 2.4e-08 33.5 6.0 0.00061 19.0 3.0 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EOO00746.1 - 0.00061 19.1 5.3 0.0087 15.3 1.9 2.9 2 1 0 2 2 2 1 Histidine biosynthesis protein PK PF00224.16 EOO00746.1 - 0.04 12.5 0.0 0.1 11.1 0.0 1.7 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.9 EOO00746.1 - 0.072 12.1 3.6 0.1 11.6 0.4 2.7 4 1 1 5 5 5 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EOO00746.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) WD40 PF00400.27 EOO00747.1 - 1.2e-07 31.3 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat adh_short PF00106.20 EOO00748.1 - 2.6e-22 79.4 0.0 3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00748.1 - 2.1e-08 34.0 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO00748.1 - 1.3e-07 31.6 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Bac_luciferase PF00296.15 EOO00748.1 - 0.0094 15.1 0.4 0.011 14.9 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Eno-Rase_NADH_b PF12242.3 EOO00748.1 - 0.026 14.2 1.2 0.032 14.0 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Metallophos PF00149.23 EOO00749.1 - 6.7e-13 48.4 3.4 2.9e-12 46.4 2.4 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_43 PF04616.9 EOO00750.1 - 2.3e-53 181.1 0.7 2.8e-53 180.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HD_assoc PF13286.1 EOO00751.1 - 0.01 16.0 0.2 0.091 13.0 0.0 2.6 3 1 0 3 3 3 0 Phosphohydrolase-associated domain DUF1656 PF07869.7 EOO00751.1 - 0.39 10.5 2.0 0.68 9.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF488 PF04343.8 EOO00752.1 - 0.16 12.3 2.9 0.29 11.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF488 MAP7 PF05672.6 EOO00752.1 - 0.37 10.1 5.0 0.52 9.6 3.4 1.4 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family Ldh_2 PF02615.9 EOO00753.1 - 6.6e-61 205.8 0.0 1.4e-60 204.7 0.0 1.5 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase ADH_zinc_N PF00107.21 EOO00754.1 - 1.2e-20 73.4 0.2 2.1e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO00754.1 - 1.2e-17 63.6 1.2 1.8e-17 63.0 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EOO00754.1 - 0.00011 21.4 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EOO00754.1 - 0.00049 19.7 0.1 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EOO00754.1 - 0.019 14.9 0.1 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EOO00754.1 - 0.053 13.1 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EOO00754.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EOO00754.1 - 0.072 13.4 0.1 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EOO00754.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S37 PF05576.6 EOO00754.1 - 0.16 10.3 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Sel1 PF08238.7 EOO00755.1 - 1.4e-46 155.8 40.7 7.2e-07 29.6 0.3 13.5 12 1 1 13 13 13 10 Sel1 repeat TPR_17 PF13431.1 EOO00755.1 - 0.0036 17.3 11.6 39 4.7 0.0 7.4 6 2 0 6 6 6 0 Tetratricopeptide repeat DUF2615 PF11027.3 EOO00755.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TPR_6 PF13174.1 EOO00755.1 - 0.68 10.5 22.0 5.4 7.7 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF59 PF01883.14 EOO00756.1 - 5.3e-05 23.1 0.0 0.00016 21.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 Peptidase_S9 PF00326.16 EOO00757.1 - 4.3e-09 35.8 0.0 6.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EOO00757.1 - 1.7e-08 34.3 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO00757.1 - 0.0003 20.5 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EOO00757.1 - 0.00099 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EOO00757.1 - 0.094 11.1 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.11 EOO00759.1 - 1e-33 116.5 39.7 1e-33 116.5 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PK PF00224.16 EOO00760.1 - 9.7e-170 563.7 6.5 1.2e-169 563.4 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EOO00760.1 - 6.3e-30 103.1 0.0 1.7e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EOO00760.1 - 0.00036 19.4 0.9 0.0016 17.3 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EOO00760.1 - 0.016 14.1 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PhoD PF09423.5 EOO00761.1 - 0.0025 16.4 0.0 0.0072 14.9 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase WD40 PF00400.27 EOO00762.1 - 8.7e-06 25.4 5.6 0.0011 18.8 0.7 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EOO00762.1 - 0.00084 18.8 0.0 0.036 13.5 0.0 2.4 1 1 1 2 2 2 1 PQQ-like domain Prothymosin PF03247.9 EOO00762.1 - 0.027 14.5 12.3 0.027 14.5 8.5 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family PQQ_3 PF13570.1 EOO00762.1 - 0.08 13.2 3.2 7.7 6.9 0.6 3.9 3 1 1 4 4 4 0 PQQ-like domain Nop14 PF04147.7 EOO00762.1 - 0.13 10.2 4.7 0.16 9.9 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EOO00762.1 - 1.2 7.0 9.4 1.8 6.5 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LicD PF04991.8 EOO00763.1 - 1.4e-36 126.5 7.6 3.8e-35 121.8 5.3 2.2 1 1 0 1 1 1 1 LicD family Fungal_trans_2 PF11951.3 EOO00764.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain AAA PF00004.24 EOO00765.1 - 1.6e-13 50.9 0.0 3.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EOO00765.1 - 0.00087 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EOO00765.1 - 0.0052 16.9 0.1 0.026 14.6 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO00765.1 - 0.019 14.7 0.1 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_2 PF07724.9 EOO00765.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) CPT PF07931.7 EOO00765.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 EOO00765.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APC_CDC26 PF10471.4 EOO00766.1 - 1.2e-10 41.9 0.3 1.2e-10 41.9 0.2 3.3 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit 1 Rtt102p PF09510.5 EOO00766.1 - 0.047 13.6 0.4 0.08 12.9 0.2 1.4 1 1 0 1 1 1 0 Rtt102p-like transcription regulator protein SPX PF03105.14 EOO00766.1 - 0.31 10.7 2.9 0.34 10.6 2.0 1.1 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 EOO00766.1 - 0.76 7.9 31.9 0.94 7.6 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_2 PF00152.15 EOO00767.1 - 3.6e-47 160.7 0.0 4.3e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Rad1 PF02144.11 EOO00768.1 - 2.9e-87 291.9 0.0 3.6e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AMP-binding PF00501.23 EOO00769.1 - 4.1e-86 288.9 0.0 5.1e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO00769.1 - 3.9e-09 37.3 0.1 1.1e-08 35.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.9 EOO00769.1 - 0.17 11.7 0.1 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Xan_ur_permease PF00860.15 EOO00770.1 - 1e-67 228.3 35.9 2.1e-66 224.0 24.9 2.1 1 1 0 1 1 1 1 Permease family MFS_1 PF07690.11 EOO00771.1 - 3.3e-35 121.4 26.2 4.9e-35 120.8 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BTB PF00651.26 EOO00772.1 - 0.0082 16.1 0.1 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain TFR_dimer PF04253.10 EOO00773.1 - 1.8e-17 63.0 0.0 3.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EOO00773.1 - 1.9e-16 60.3 0.1 4.1e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EOO00773.1 - 2.5e-07 30.3 0.6 1.4e-06 27.8 0.1 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 EOO00773.1 - 0.04 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Nicastrin TFIIS_M PF07500.9 EOO00774.1 - 1.3e-27 96.1 0.5 2.4e-27 95.2 0.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EOO00774.1 - 2.2e-18 65.5 5.0 3.4e-18 64.9 3.5 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EOO00774.1 - 3.1e-14 52.1 0.1 7.3e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-ZPR1 PF03367.8 EOO00774.1 - 0.00053 19.1 1.0 1.1 8.4 0.0 3.1 3 0 0 3 3 3 2 ZPR1 zinc-finger domain MIF4G_like_2 PF09090.6 EOO00774.1 - 0.0065 15.7 1.1 0.06 12.5 0.0 2.1 2 0 0 2 2 2 1 MIF4G like DUF3943 PF13084.1 EOO00774.1 - 0.0094 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3943) Hus1 PF04005.7 EOO00774.1 - 0.049 12.5 0.3 0.082 11.8 0.2 1.3 1 0 0 1 1 1 0 Hus1-like protein GvpL_GvpF PF06386.6 EOO00774.1 - 0.079 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF547 PF04784.9 EOO00774.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Cytochrome_C554 PF13435.1 EOO00774.1 - 3 7.9 8.0 0.61 10.1 2.9 1.7 2 0 0 2 2 2 0 Cytochrome c554 and c-prime NIF PF03031.13 EOO00775.1 - 5.7e-39 133.3 0.5 1.7e-19 70.0 0.0 2.0 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase CS PF04969.11 EOO00776.1 - 6.2e-17 61.9 0.1 1.4e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 CS domain STAT1_TAZ2bind PF12162.3 EOO00777.1 - 0.081 12.3 0.0 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain RGS PF00615.14 EOO00778.1 - 2.3e-11 43.8 0.0 3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain MFS_1 PF07690.11 EOO00779.1 - 4.7e-37 127.5 74.4 2.3e-36 125.2 47.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO00779.1 - 6.3e-13 47.7 31.8 2.2e-12 46.0 22.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EOO00779.1 - 7e-13 47.9 16.8 7e-13 47.9 11.7 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00780.1 - 1e-09 37.6 13.4 4.5e-05 22.3 6.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Rhomboid PF01694.17 EOO00780.1 - 0.038 14.0 3.9 0.1 12.5 2.7 1.8 1 1 0 1 1 1 0 Rhomboid family DUF1228 PF06779.9 EOO00780.1 - 0.26 11.3 5.2 5 7.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Ank_2 PF12796.2 EOO00781.1 - 2.8e-20 72.4 0.1 1.2e-09 38.4 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EOO00781.1 - 2.1e-11 43.0 0.5 0.0094 15.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EOO00781.1 - 1.2e-09 38.3 0.0 0.0012 19.2 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO00781.1 - 1.6e-09 37.7 0.3 0.082 13.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO00781.1 - 1.3e-07 31.1 0.1 0.22 11.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M6 PF05547.6 EOO00782.1 - 5.7e-23 80.8 2.7 9.1e-22 76.8 1.9 2.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 DUF1401 PF07180.6 EOO00782.1 - 0.21 11.3 0.4 0.43 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1401) DUF1713 PF08213.6 EOO00783.1 - 8.8e-12 44.4 20.4 1.5e-11 43.7 14.1 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) EF_assoc_1 PF08355.7 EOO00783.1 - 0.12 11.6 0.3 0.23 10.7 0.2 1.5 1 0 0 1 1 1 0 EF hand associated ER_lumen_recept PF00810.13 EOO00784.1 - 3.1e-35 121.8 5.7 4.7e-35 121.2 4.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EOO00784.1 - 0.15 11.6 0.0 0.15 11.6 0.0 3.1 4 0 0 4 4 4 0 PQ loop repeat adh_short PF00106.20 EOO00785.1 - 6.7e-21 74.9 0.5 7.8e-21 74.6 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00785.1 - 3.7e-10 39.7 0.1 4.4e-10 39.5 0.1 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO00785.1 - 0.00024 20.0 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EOO00785.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 EOO00785.1 - 0.034 13.9 0.5 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 ThiF family Eno-Rase_NADH_b PF12242.3 EOO00785.1 - 0.073 12.8 1.6 0.17 11.6 1.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LRR_4 PF12799.2 EOO00786.1 - 3.2e-46 154.2 23.2 3e-13 49.0 0.9 6.8 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EOO00786.1 - 2.1e-23 81.8 35.8 5.3e-08 32.4 0.9 5.2 2 1 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EOO00786.1 - 3.2e-13 47.7 22.2 0.38 10.9 0.1 11.5 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.1 EOO00786.1 - 5.9e-13 47.4 12.4 0.22 11.6 0.1 9.9 6 4 4 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 EOO00786.1 - 7.6e-11 40.3 11.5 2.5 8.6 0.0 9.5 10 0 0 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 EOO00786.1 - 2.8e-10 40.0 7.4 0.00034 20.2 0.9 3.4 1 1 2 3 3 3 3 Leucine-rich repeat p450 PF00067.17 EOO00787.1 - 7.8e-31 107.0 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.19 EOO00788.1 - 6.4e-30 104.0 0.3 1e-29 103.3 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UQ_con PF00179.21 EOO00789.1 - 1.4e-48 163.8 0.0 1.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO00789.1 - 7.6e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO00789.1 - 0.00077 19.3 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EOO00789.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain BRE PF06113.7 EOO00789.1 - 0.2 10.6 0.4 0.3 10.0 0.2 1.4 1 1 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) PCI PF01399.22 EOO00790.1 - 1.9e-06 28.1 0.0 2.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 PCI domain HrpB7 PF09486.5 EOO00790.1 - 0.01 15.7 3.1 0.022 14.6 2.1 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) YhzD PF14120.1 EOO00790.1 - 0.078 12.8 0.3 0.26 11.2 0.2 1.8 1 0 0 1 1 1 0 YhzD-like protein Cellulase PF00150.13 EOO00791.1 - 2.1e-21 76.3 1.4 3.2e-21 75.7 1.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EOO00791.1 - 3.1e-13 49.1 13.9 3.1e-13 49.1 9.6 3.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.10 EOO00791.1 - 0.00039 19.6 0.2 0.00095 18.3 0.1 1.6 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 EOO00791.1 - 0.0015 17.4 0.2 0.0046 15.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EOO00791.1 - 0.0081 16.5 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 EOO00791.1 - 0.019 14.0 0.1 0.019 14.0 0.1 2.1 3 0 0 3 3 3 0 Glycosyl hydrolase family 10 FRG1 PF06229.7 EOO00793.1 - 6e-53 179.1 0.4 6e-53 179.1 0.3 1.5 2 0 0 2 2 2 1 FRG1-like family LEA_2 PF03168.8 EOO00793.1 - 0.1 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein ABC_membrane_2 PF06472.10 EOO00794.1 - 3.4e-98 328.2 0.7 6.7e-97 324.0 0.0 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EOO00794.1 - 2.9e-16 60.0 0.0 6.4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EOO00794.1 - 0.0014 18.6 0.2 0.0081 16.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EOO00794.1 - 0.012 16.0 4.5 0.18 12.1 3.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EOO00794.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EOO00794.1 - 0.026 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EOO00794.1 - 0.027 15.3 0.1 0.18 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EOO00794.1 - 0.031 13.4 0.1 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI End3 PF12761.2 EOO00794.1 - 0.087 12.4 1.0 0.19 11.3 0.7 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 AAA_16 PF13191.1 EOO00794.1 - 0.13 12.2 0.2 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EOO00794.1 - 0.16 12.1 0.0 0.68 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp PF00026.18 EOO00795.1 - 4.6e-41 141.0 8.5 6.4e-41 140.6 5.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO00795.1 - 0.001 19.0 2.8 0.0011 19.0 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal BRX PF08381.6 EOO00795.1 - 0.15 11.1 1.5 0.28 10.2 1.0 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 WSC PF01822.14 EOO00796.1 - 3.4e-33 113.4 37.3 4.1e-17 61.8 9.9 2.7 2 0 0 2 2 2 2 WSC domain PQQ_3 PF13570.1 EOO00796.1 - 1.5 9.2 9.2 11 6.4 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Pyr_redox_3 PF13738.1 EOO00797.1 - 3.6e-22 79.4 0.0 1.1e-20 74.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO00797.1 - 1.6e-17 62.9 0.0 2.3e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EOO00797.1 - 3.9e-10 39.6 0.0 1.2e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EOO00797.1 - 7e-07 28.4 0.0 3.1e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EOO00797.1 - 0.00015 20.9 0.0 0.063 12.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EOO00797.1 - 0.00027 20.7 0.1 0.11 12.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF4147 PF13660.1 EOO00797.1 - 0.25 10.4 0.0 3.7 6.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Lipase_GDSL_2 PF13472.1 EOO00798.1 - 8.8e-12 45.5 2.0 1.2e-11 45.0 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO00798.1 - 1.6e-09 37.9 7.3 5.1e-09 36.3 5.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MAT1 PF06391.8 EOO00799.1 - 3.5e-29 101.8 12.1 4.7e-29 101.4 8.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EOO00799.1 - 0.00082 18.9 5.1 0.002 17.7 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EOO00799.1 - 0.0029 17.2 5.7 0.0045 16.6 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) eIF-3_zeta PF05091.7 EOO00799.1 - 0.011 14.3 2.9 0.013 14.1 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-RING_5 PF14634.1 EOO00799.1 - 0.014 15.0 9.5 0.21 11.3 7.1 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EOO00799.1 - 0.015 15.3 7.3 0.041 13.9 5.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EOO00799.1 - 0.023 14.5 6.5 0.066 13.0 4.6 1.7 1 1 0 1 1 1 0 Ring finger domain U79_P34 PF03064.11 EOO00799.1 - 0.58 9.6 11.0 1 8.8 7.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Atg14 PF10186.4 EOO00799.1 - 0.59 9.0 6.2 0.84 8.5 4.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PV-1 PF06637.6 EOO00799.1 - 1.3 7.4 13.0 2 6.9 9.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-UDP PF14569.1 EOO00799.1 - 1.6 8.5 4.4 5.2 6.8 3.1 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 EOO00799.1 - 1.7 8.2 10.4 25 4.5 7.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain OPT PF03169.10 EOO00800.1 - 1.5e-142 476.1 44.4 1.8e-142 475.9 30.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GMC_oxred_N PF00732.14 EOO00801.1 - 8.7e-42 143.2 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO00801.1 - 5.6e-32 111.0 0.0 1.3e-31 109.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FTA2 PF13095.1 EOO00802.1 - 4.6e-19 68.8 0.0 6.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MARVEL PF01284.18 EOO00803.1 - 7e-21 74.5 20.0 8.5e-21 74.2 13.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Lig_chan PF00060.21 EOO00803.1 - 7.1 6.3 6.7 0.76 9.4 1.4 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel Sugar_tr PF00083.19 EOO00804.1 - 3.3e-63 213.8 28.5 4.3e-35 121.1 9.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00804.1 - 1.1e-19 70.3 31.3 2.9e-17 62.4 4.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO00804.1 - 0.00013 20.3 1.0 0.00022 19.5 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 EOO00805.1 - 4.2e-31 107.8 0.0 5.2e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PAS_3 PF08447.6 EOO00805.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Glyco_hydro_18 PF00704.23 EOO00806.1 - 5.8e-48 164.0 0.1 6.8e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CDP-OH_P_transf PF01066.16 EOO00807.1 - 1.6e-18 66.8 2.2 1.6e-18 66.8 1.5 2.6 4 0 0 4 4 4 1 CDP-alcohol phosphatidyltransferase Spt5-NGN PF03439.8 EOO00808.1 - 5.3e-26 90.1 0.0 9.7e-26 89.3 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EOO00808.1 - 1.9e-16 60.4 10.2 1.9e-16 60.4 7.0 5.1 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EOO00808.1 - 8.2e-06 25.3 21.0 6.6e-05 22.4 0.3 5.6 7 0 0 7 7 7 2 KOW motif CTD PF12815.2 EOO00808.1 - 0.016 15.5 1.7 0.016 15.5 1.2 2.0 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 YajC PF02699.10 EOO00808.1 - 1.5 8.5 8.3 1.6 8.4 0.1 3.7 3 1 1 4 4 4 0 Preprotein translocase subunit adh_short PF00106.20 EOO00809.1 - 1.2e-26 93.5 0.0 1.9e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00809.1 - 3.9e-23 82.4 0.0 5.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00809.1 - 1.4e-09 37.8 0.1 3.6e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EOO00809.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EOO00809.1 - 0.021 13.9 0.0 0.05 12.7 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) UDPG_MGDP_dh_N PF03721.9 EOO00809.1 - 0.026 13.9 1.2 0.12 11.7 0.9 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RepC PF06504.6 EOO00809.1 - 0.13 11.1 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) WD40 PF00400.27 EOO00810.1 - 1.9e-21 75.0 9.6 4e-08 32.8 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Amidase PF01425.16 EOO00811.1 - 0.0008 18.3 0.0 0.0019 17.1 0.0 1.6 1 1 0 1 1 1 1 Amidase FAD_binding_6 PF00970.19 EOO00812.1 - 4.3e-08 33.1 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EOO00812.1 - 6.2e-08 32.9 0.0 9.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EOO00812.1 - 2e-06 28.3 0.0 3.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EOO00812.1 - 0.0054 16.6 0.2 0.091 12.6 0.0 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EOO00812.1 - 0.043 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain Cation_efflux PF01545.16 EOO00813.1 - 7.6e-76 254.8 8.6 4.1e-75 252.4 6.0 1.8 1 1 0 1 1 1 1 Cation efflux family Prefoldin_3 PF13758.1 EOO00814.1 - 5.2e-31 106.3 0.2 1.5e-30 104.8 0.2 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EOO00814.1 - 4.1e-22 78.9 22.5 1.5e-21 77.1 0.0 6.0 5 2 0 5 5 5 2 Domain of unknown function (DUF3835) Scm3 PF10384.4 EOO00816.1 - 4.1e-24 83.8 0.3 6.1e-24 83.2 0.2 1.3 1 0 0 1 1 1 1 Centromere protein Scm3 Ank_4 PF13637.1 EOO00817.1 - 2.1e-13 50.3 0.5 3e-07 30.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EOO00817.1 - 2.9e-11 43.5 0.1 1.6e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EOO00817.1 - 8.8e-11 41.0 0.9 1.5e-06 27.7 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EOO00817.1 - 1.5e-10 40.9 0.1 2.4e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO00817.1 - 4.8e-06 26.3 0.2 0.0049 16.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat NQR2_RnfD_RnfE PF03116.10 EOO00818.1 - 0.068 12.3 0.9 0.093 11.9 0.7 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family IncA PF04156.9 EOO00819.1 - 8.2 5.9 13.0 11 5.5 1.9 2.7 2 1 0 2 2 2 0 IncA protein MFS_1 PF07690.11 EOO00820.1 - 1.8e-37 128.8 49.2 1.1e-33 116.4 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.1 EOO00821.1 - 0.0086 16.9 0.0 0.016 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_28 PF02636.12 EOO00822.1 - 4.3e-36 124.6 0.0 6.4e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EOO00822.1 - 0.026 13.4 0.0 0.055 12.3 0.0 1.4 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Glyco_hydro_61 PF03443.9 EOO00823.1 - 2e-51 174.8 0.4 2.3e-51 174.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ETF PF01012.16 EOO00823.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Electron transfer flavoprotein domain Acetyltransf_3 PF13302.1 EOO00824.1 - 5.4e-37 127.1 0.0 7.8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EOO00824.1 - 5e-07 29.8 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO00824.1 - 4.1e-06 26.7 0.0 0.0042 17.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EOO00824.1 - 0.0019 18.1 0.1 2.9 7.7 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain VWA_2 PF13519.1 EOO00825.1 - 3.8e-13 49.9 1.5 3.8e-13 49.9 1.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EOO00825.1 - 5.7e-12 45.7 1.8 1.4e-11 44.4 1.2 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EOO00825.1 - 0.006 15.7 0.2 0.2 10.7 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EOO00825.1 - 0.0066 16.2 0.2 0.16 11.8 0.2 2.2 1 1 0 1 1 1 1 vWA found in TerF C terminus VSP PF03302.8 EOO00825.1 - 0.086 11.4 1.7 0.14 10.7 1.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein CARDB PF07705.6 EOO00825.1 - 0.087 12.8 1.2 14 5.8 0.0 3.1 3 1 0 3 3 3 0 CARDB ABC2_membrane PF01061.19 EOO00826.1 - 1.3e-96 321.7 55.8 1.4e-50 171.3 14.3 2.5 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EOO00826.1 - 1.4e-38 130.6 5.5 5.8e-34 115.8 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EOO00826.1 - 8.9e-35 119.9 0.0 2.4e-16 60.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EOO00826.1 - 4e-20 71.6 0.0 9.4e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EOO00826.1 - 1.9e-07 30.6 0.0 9.7e-05 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO00826.1 - 5.4e-07 29.7 0.7 1.1e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EOO00826.1 - 3.1e-05 23.2 0.0 0.0073 15.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EOO00826.1 - 0.00019 22.2 0.0 1 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EOO00826.1 - 0.00021 21.1 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EOO00826.1 - 0.0004 19.8 0.8 0.0047 16.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EOO00826.1 - 0.00059 19.3 0.8 0.025 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain PDR_assoc PF08370.6 EOO00826.1 - 0.0012 18.3 4.6 0.018 14.5 0.1 3.6 4 0 0 4 4 3 1 Plant PDR ABC transporter associated AAA_18 PF13238.1 EOO00826.1 - 0.0036 17.5 0.0 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EOO00826.1 - 0.0044 17.1 0.4 0.72 9.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EOO00826.1 - 0.0046 16.2 0.0 2.7 7.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EOO00826.1 - 0.0087 16.0 0.0 0.91 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EOO00826.1 - 0.013 14.5 41.6 0.015 14.3 10.9 3.1 2 2 0 2 2 2 0 ABC-2 family transporter protein AAA_30 PF13604.1 EOO00826.1 - 0.037 13.5 0.1 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EOO00826.1 - 0.044 13.4 0.1 0.89 9.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EOO00826.1 - 0.047 13.3 0.6 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EOO00826.1 - 0.047 13.6 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EOO00826.1 - 0.058 13.1 0.9 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 EOO00826.1 - 0.086 12.4 1.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EOO00826.1 - 0.22 11.7 0.0 0.52 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2273 PF10031.4 EOO00826.1 - 5.2 6.7 10.1 0.27 10.8 0.9 2.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) adh_short PF00106.20 EOO00827.1 - 1.4e-16 60.9 0.1 4e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO00827.1 - 1e-05 25.3 0.1 2.5e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EOO00827.1 - 0.00017 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO00827.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EOO00827.1 - 0.048 13.4 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MBOAT PF03062.14 EOO00828.1 - 3.1e-45 154.7 21.0 3.1e-45 154.7 14.5 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NAD_binding_8 PF13450.1 EOO00829.1 - 1.5e-08 34.5 0.0 3.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EOO00829.1 - 6.1e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO00829.1 - 0.00026 20.9 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO00829.1 - 0.00026 20.1 0.1 0.00095 18.3 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EOO00829.1 - 0.00077 18.4 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO00829.1 - 0.005 15.7 0.0 0.012 14.5 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF498 PF04430.9 EOO00829.1 - 0.0062 16.0 0.0 0.94 9.0 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF498/DUF598) HI0933_like PF03486.9 EOO00829.1 - 0.042 12.3 0.2 0.064 11.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FMO-like PF00743.14 EOO00829.1 - 0.043 12.0 1.0 0.12 10.6 0.1 2.0 2 1 0 2 2 2 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 EOO00829.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CTP_transf_2 PF01467.21 EOO00830.1 - 0.00064 19.7 0.8 0.0059 16.6 0.6 2.5 1 1 0 1 1 1 1 Cytidylyltransferase Feld-I_B PF09252.5 EOO00830.1 - 0.23 11.4 0.5 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Allergen Fel d I-B chain Methyltransf_23 PF13489.1 EOO00831.1 - 9.2e-17 61.2 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EOO00831.1 - 7.1e-15 54.8 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Methyltransf_18 PF12847.2 EOO00831.1 - 2e-10 41.2 0.1 1.7e-08 35.0 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain NAD_binding_10 PF13460.1 EOO00831.1 - 2.9e-10 40.4 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_31 PF13847.1 EOO00831.1 - 4.9e-10 39.1 0.0 2.8e-08 33.4 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO00831.1 - 3.4e-09 37.0 0.0 3e-08 34.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00831.1 - 9.8e-08 32.3 0.0 4.1e-06 27.1 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO00831.1 - 0.00026 20.2 0.0 0.0039 16.3 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EOO00831.1 - 0.0093 16.3 0.0 0.77 10.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO00831.1 - 0.013 14.5 0.0 0.041 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EOO00831.1 - 0.021 14.7 0.1 0.054 13.4 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EOO00831.1 - 0.024 14.0 0.0 0.073 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EOO00831.1 - 0.053 12.9 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase tRNA_anti-codon PF01336.20 EOO00831.1 - 0.084 12.7 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain PrmA PF06325.8 EOO00831.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Acyl-CoA_dh_1 PF00441.19 EOO00832.1 - 8.9e-24 84.3 0.1 1.5e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EOO00832.1 - 6.2e-12 46.0 0.0 6.2e-12 46.0 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EOO00832.1 - 3.6e-08 33.7 0.0 7.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EOO00832.1 - 1.6e-07 30.7 0.0 4.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain PCI PF01399.22 EOO00833.1 - 1.1e-09 38.5 0.0 3.2e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 PCI domain TPR_11 PF13414.1 EOO00833.1 - 0.025 14.2 0.3 0.082 12.5 0.1 1.9 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EOO00833.1 - 0.11 12.4 0.1 0.52 10.3 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 EOO00834.1 - 8.3e-20 71.5 0.0 1.8e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO00834.1 - 1.9e-19 70.1 0.1 3e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00834.1 - 5.1e-05 23.0 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 KR domain PTR2 PF00854.16 EOO00835.1 - 6.7e-40 137.0 13.6 7.1e-38 130.3 9.4 2.7 1 1 0 1 1 1 1 POT family Thiolase_N PF00108.18 EOO00836.1 - 3.2e-90 301.6 1.1 4.6e-90 301.1 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EOO00836.1 - 4.4e-45 152.0 0.1 1.1e-44 150.7 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EOO00836.1 - 0.00023 20.7 1.2 0.00023 20.7 0.8 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EOO00836.1 - 0.14 11.8 4.7 0.86 9.3 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.11 EOO00837.1 - 7.6e-05 21.5 17.7 7.6e-05 21.5 12.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Totivirus_coat PF05518.6 EOO00837.1 - 0.0062 14.4 0.3 0.0082 14.0 0.2 1.1 1 0 0 1 1 1 1 Totivirus coat protein GNAT_acetyltr_2 PF13718.1 EOO00838.1 - 3.7e-80 267.8 0.0 6.5e-80 267.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EOO00838.1 - 9.3e-66 220.8 0.0 3.7e-65 218.8 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EOO00838.1 - 2e-39 133.1 0.1 4.7e-39 131.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EOO00838.1 - 1.6e-33 114.7 0.2 5e-33 113.2 0.2 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EOO00838.1 - 0.013 15.6 0.0 0.078 13.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sulfatase PF00884.18 EOO00839.1 - 5e-63 213.1 0.3 6.1e-63 212.8 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EOO00839.1 - 0.0042 16.4 0.2 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase E1-E2_ATPase PF00122.15 EOO00841.1 - 1.1e-54 184.9 0.2 2.3e-54 183.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EOO00841.1 - 1.7e-46 159.3 3.4 3.7e-46 158.2 2.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EOO00841.1 - 4.6e-43 145.1 0.5 7e-11 42.1 0.1 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EOO00841.1 - 3.3e-14 53.4 0.0 9.3e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO00841.1 - 4.4e-07 29.7 1.0 0.00011 21.9 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HARE-HTH PF05066.8 EOO00841.1 - 0.011 16.0 0.0 13 6.2 0.0 3.5 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain Peroxidase_2 PF01328.12 EOO00841.1 - 0.018 13.7 0.1 2.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Peroxidase, family 2 DUF1996 PF09362.5 EOO00842.1 - 7.4e-53 179.6 0.1 9.1e-52 176.0 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1212 PF06738.7 EOO00843.1 - 2.5e-57 193.4 3.3 5.9e-53 179.2 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EOO00843.1 - 2.5e-25 88.9 29.8 8.4e-15 54.8 0.8 3.5 4 0 0 4 4 4 3 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EOO00843.1 - 0.015 15.5 2.9 0.015 15.5 2.0 2.2 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) MFS_1 PF07690.11 EOO00844.1 - 5.7e-12 45.0 6.8 9.8e-10 37.6 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO00844.1 - 3e-07 29.3 1.2 5.7e-07 28.4 0.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EOO00844.1 - 2.9e-05 22.6 0.2 0.0038 15.6 0.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Histidinol_dh PF00815.15 EOO00846.1 - 3.2e-105 352.1 0.9 4e-105 351.8 0.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PAS_10 PF13596.1 EOO00846.1 - 0.043 14.0 0.5 0.56 10.5 0.1 2.2 1 1 1 2 2 2 0 PAS domain Blt1 PF12754.2 EOO00846.1 - 0.22 11.0 1.6 0.44 10.1 1.1 1.4 1 0 0 1 1 1 0 Cell-cycle control medial ring component Sugar_tr PF00083.19 EOO00848.1 - 7.8e-32 110.4 8.4 2.8e-20 72.3 0.2 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter UDG PF03167.14 EOO00849.1 - 8.1e-25 87.0 0.2 1.8e-24 85.9 0.1 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF1772 PF08592.6 EOO00850.1 - 3.6e-21 75.3 0.9 3.9e-21 75.2 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Chromo PF00385.19 EOO00850.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ABC_membrane PF00664.18 EOO00851.1 - 1e-21 77.6 4.3 1.5e-21 76.9 3.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EOO00851.1 - 4.9e-09 36.6 0.0 1.8e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EOO00851.1 - 3.3e-05 24.0 0.2 7.5e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EOO00851.1 - 0.00042 19.6 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Peptidase_M16 PF00675.15 EOO00852.1 - 3.9e-57 192.2 0.9 8e-57 191.1 0.3 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EOO00852.1 - 2.4e-40 138.1 0.1 1.1e-38 132.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain F-actin_cap_A PF01267.12 EOO00852.1 - 0.044 12.8 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Pro_CA PF00484.14 EOO00853.1 - 6.1e-12 45.7 0.0 8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_S17 PF00366.15 EOO00854.1 - 1.5e-30 104.9 0.8 2.3e-30 104.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 WD40 PF00400.27 EOO00855.1 - 8.2e-30 101.6 0.9 1.9e-08 33.8 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 EOO00855.1 - 9e-06 25.5 0.0 0.018 14.7 0.0 2.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EOO00855.1 - 0.027 13.9 0.0 5 6.7 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.16 EOO00855.1 - 0.054 12.0 0.1 12 4.3 0.0 2.7 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 EOO00855.1 - 0.067 11.9 0.0 0.19 10.4 0.1 1.6 2 0 0 2 2 2 0 Nup133 N terminal like DUF4609 PF15382.1 EOO00855.1 - 0.075 12.7 0.5 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Pyocin_S PF06958.7 EOO00855.1 - 0.092 13.1 1.1 9.6 6.5 0.2 2.3 2 0 0 2 2 2 0 S-type Pyocin 4HBT_2 PF13279.1 EOO00856.1 - 6.6e-09 36.2 0.0 9.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TMEM191C PF15194.1 EOO00856.1 - 0.078 12.8 1.3 11 5.9 0.0 2.7 2 1 1 3 3 3 0 TMEM191C family APG6 PF04111.7 EOO00857.1 - 8.8e-127 422.4 0.0 1.1e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 EOO00857.1 - 1.5 8.3 10.4 2.5 7.6 7.2 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EOO00857.1 - 3.9 5.2 6.7 5.2 4.7 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribophorin_II PF05817.9 EOO00858.1 - 1.6e-26 92.7 0.1 2e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF1049 PF06305.6 EOO00858.1 - 2.7 7.5 6.5 4 6.9 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Aldedh PF00171.17 EOO00859.1 - 7.8e-159 528.9 0.0 8.8e-159 528.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EOO00859.1 - 0.046 12.9 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ELO PF01151.13 EOO00860.1 - 7.1e-61 205.6 13.7 9.1e-61 205.3 9.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short PF00106.20 EOO00861.1 - 7.4e-29 100.7 1.3 9.5e-29 100.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00861.1 - 1.2e-28 100.4 0.0 1.4e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00861.1 - 3.1e-16 59.5 0.4 4.3e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO00861.1 - 0.1 12.5 0.4 0.23 11.4 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding TPR_12 PF13424.1 EOO00862.1 - 0.00034 20.4 0.7 0.012 15.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 EOO00862.1 - 0.2 12.2 3.7 2.3 8.8 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO00862.1 - 0.31 11.7 4.2 4.9 8.0 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EOO00863.1 - 7.5e-12 44.6 0.0 1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF294 PF03445.8 EOO00863.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Ribosomal_L18ae PF01775.12 EOO00865.1 - 3.3e-59 198.1 0.3 4.2e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Pyr_redox_3 PF13738.1 EOO00866.1 - 9.3e-20 71.5 0.0 1.9e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO00866.1 - 9.9e-15 53.7 0.2 3.9e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EOO00866.1 - 2.3e-10 40.3 0.0 6.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EOO00866.1 - 3.1e-06 26.3 0.0 0.012 14.5 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EOO00866.1 - 1.2e-05 25.1 0.0 4.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EOO00866.1 - 0.00012 21.1 0.0 0.0071 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Glyco_transf_28 PF03033.15 EOO00867.1 - 2.7e-20 72.5 0.3 1.7e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EOO00867.1 - 6.1e-06 25.0 0.1 1.2e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EOO00867.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Hydantoinase_B PF02538.9 EOO00868.1 - 2.8e-185 616.5 0.0 4.1e-185 615.9 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO00868.1 - 3e-90 302.2 0.5 5.3e-90 301.4 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase F_bP_aldolase PF01116.15 EOO00868.1 - 1.3e-72 244.3 0.1 2.4e-72 243.4 0.1 1.5 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short PF00106.20 EOO00869.1 - 7.4e-21 74.7 5.0 1.1e-20 74.2 3.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00869.1 - 3.8e-10 39.7 0.6 6.1e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO00869.1 - 1.7e-07 31.4 0.8 3.5e-07 30.4 0.3 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EOO00869.1 - 8.5e-07 28.9 0.1 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO00869.1 - 3.6e-05 23.3 0.1 6.7e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EOO00869.1 - 0.0022 17.3 0.3 0.0045 16.2 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EOO00869.1 - 0.0078 15.1 0.9 0.012 14.4 0.6 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EOO00869.1 - 0.043 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EOO00870.1 - 6.3e-15 55.2 0.0 7.4e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EOO00870.1 - 8.8e-09 35.7 0.1 2.2e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EOO00870.1 - 2.8e-06 26.2 0.0 0.015 13.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EOO00870.1 - 7.1e-06 25.1 0.0 0.012 14.4 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EOO00870.1 - 4.4e-05 22.8 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO00870.1 - 0.00018 21.5 0.0 0.00044 20.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EOO00870.1 - 0.00061 18.8 0.0 0.00088 18.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EOO00870.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.20 EOO00871.1 - 6.7e-26 90.0 0.4 1.2e-25 89.2 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EOO00871.1 - 1.8e-09 37.5 0.1 4.2e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO00871.1 - 2.4e-09 37.0 0.1 5.2e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EOO00871.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RasGAP_C PF03836.10 EOO00872.1 - 2e-48 163.7 3.7 7.2e-48 161.8 2.5 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EOO00872.1 - 5.2e-47 160.0 0.0 1.5e-46 158.5 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EOO00872.1 - 5.8e-07 28.5 20.2 1 9.1 0.1 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif Methyltransf_23 PF13489.1 EOO00873.1 - 4.7e-16 58.9 0.0 6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO00873.1 - 8.7e-05 22.1 0.0 0.1 12.1 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EOO00873.1 - 0.00041 20.9 0.1 0.31 11.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.9 EOO00873.1 - 0.01 15.1 0.0 0.099 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EOO00873.1 - 0.047 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 EOO00873.1 - 0.082 13.3 0.0 3.5 8.1 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 EOO00873.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF155 PF02582.9 EOO00874.1 - 1.6e-59 200.7 0.1 2.5e-59 200.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 L31 PF09784.4 EOO00875.1 - 2 8.5 5.5 4.2 7.4 2.7 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 PBP_sp32 PF07222.7 EOO00875.1 - 5.1 6.1 7.5 2 7.5 0.3 2.2 1 1 1 2 2 2 0 Proacrosin binding protein sp32 Atg14 PF10186.4 EOO00876.1 - 9e-46 156.1 12.5 3.7e-37 127.9 6.6 2.1 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Tox-ODYAM1 PF15642.1 EOO00876.1 - 0.088 11.4 3.5 0.12 11.0 2.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF501 PF04417.7 EOO00876.1 - 0.41 10.4 2.9 0.65 9.8 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF501) Mnd1 PF03962.10 EOO00876.1 - 0.66 9.6 6.9 1 8.9 4.8 1.2 1 0 0 1 1 1 0 Mnd1 family HAUS6_N PF14661.1 EOO00876.1 - 8.8 5.6 8.6 14 4.9 6.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pyr_redox_3 PF13738.1 EOO00877.1 - 3.6e-14 53.2 0.0 3.1e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO00877.1 - 5e-12 44.7 0.0 6e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EOO00877.1 - 0.011 15.6 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2OG-FeII_Oxy PF03171.15 EOO00878.1 - 0.034 14.4 0.0 0.071 13.4 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SprT-like PF10263.4 EOO00879.1 - 5.3e-15 55.4 0.0 7.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Pkinase PF00069.20 EOO00880.1 - 3.4e-46 157.5 0.0 3e-45 154.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00880.1 - 3.1e-32 111.6 0.0 4.2e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO00880.1 - 0.0033 16.4 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO00880.1 - 0.0076 15.3 0.1 0.039 12.9 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EOO00880.1 - 0.084 12.5 0.6 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ArabFuran-catal PF09206.6 EOO00881.1 - 7.5e-163 541.0 22.0 1.1e-162 540.5 15.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EOO00881.1 - 1.5e-63 212.8 4.5 2.4e-63 212.1 3.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) DivIC PF04977.10 EOO00882.1 - 0.029 13.8 3.2 1.1 8.7 0.0 3.2 3 0 0 3 3 3 0 Septum formation initiator HCMV_UL139 PF12507.3 EOO00882.1 - 0.1 12.7 1.3 0.39 10.8 0.5 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein APG6 PF04111.7 EOO00882.1 - 0.89 8.5 4.7 0.75 8.7 1.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 CCDC-167 PF15188.1 EOO00882.1 - 8.7 6.3 7.1 7.7 6.5 2.5 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 AAA PF00004.24 EOO00883.1 - 2e-17 63.5 0.0 4.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EOO00883.1 - 0.00082 19.4 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 EOO00883.1 - 0.007 15.8 0.2 0.14 11.5 0.0 2.5 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EOO00883.1 - 0.014 15.2 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EOO00883.1 - 0.021 14.9 1.5 0.17 11.9 0.1 2.7 2 1 1 3 3 3 0 AAA domain CPT PF07931.7 EOO00883.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 EOO00883.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EOO00883.1 - 0.066 14.0 3.6 0.07 13.9 0.1 3.0 3 2 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EOO00883.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Big_3_4 PF13754.1 EOO00884.1 - 0.039 14.2 0.1 0.039 14.2 0.1 2.3 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) ABC_tran PF00005.22 EOO00885.1 - 1.6e-51 174.2 0.0 1.4e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EOO00885.1 - 3.5e-38 131.5 16.3 7.3e-22 78.0 5.3 3.7 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EOO00885.1 - 1.9e-10 40.3 0.0 6.5e-05 22.2 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EOO00885.1 - 3.7e-05 23.7 1.6 0.049 13.6 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EOO00885.1 - 0.00016 20.6 0.0 0.065 12.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EOO00885.1 - 0.00018 20.9 0.0 0.092 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EOO00885.1 - 0.00031 20.1 0.5 0.92 9.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EOO00885.1 - 0.00086 19.4 0.0 6.2 6.9 0.0 3.5 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EOO00885.1 - 0.0025 17.0 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EOO00885.1 - 0.0033 17.7 0.1 0.32 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EOO00885.1 - 0.0049 16.8 0.1 6.1 6.7 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.1 EOO00885.1 - 0.0082 15.7 0.0 2.3 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EOO00885.1 - 0.015 15.7 0.1 4.8 7.7 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EOO00885.1 - 0.018 14.9 0.1 4.8 7.1 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EOO00885.1 - 0.019 14.8 3.1 0.98 9.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 EOO00885.1 - 0.031 13.2 0.0 0.55 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.18 EOO00885.1 - 0.045 13.7 2.4 0.37 10.7 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EOO00885.1 - 0.053 12.9 0.0 12 5.3 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EOO00885.1 - 0.23 11.6 0.0 22 5.2 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AMP-binding PF00501.23 EOO00886.1 - 5.2e-74 249.1 0.0 7.1e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 EOO00886.1 - 3.7e-42 144.1 0.4 6.2e-42 143.3 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding_C PF13193.1 EOO00886.1 - 6.1e-09 36.6 0.0 1.9e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_C PF13766.1 EOO00886.1 - 0.03 14.4 0.3 0.07 13.2 0.2 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region DUF370 PF04025.7 EOO00886.1 - 0.044 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF370) LETM1 PF07766.8 EOO00887.1 - 2.9e-109 364.2 1.0 2.9e-109 364.2 0.7 1.5 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EOO00887.1 - 1.8e-05 24.1 0.0 0.17 11.4 0.0 3.5 3 0 0 3 3 3 3 SAP domain adh_short_C2 PF13561.1 EOO00888.1 - 1.1e-24 87.5 0.0 1.4e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO00888.1 - 1e-21 77.5 0.5 1.4e-21 77.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00888.1 - 1.7e-07 31.0 0.3 2.4e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EOO00888.1 - 0.052 13.3 1.5 0.34 10.7 0.2 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EOO00888.1 - 0.075 12.4 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.17 EOO00889.1 - 7.7e-14 51.0 0.0 1.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO00889.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO00889.1 - 4.9e-08 32.7 0.0 6.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EOO00889.1 - 3.9 7.9 7.7 8 6.9 5.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Abhydrolase_6 PF12697.2 EOO00890.1 - 7e-23 81.6 0.7 1e-22 81.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO00890.1 - 1.1e-09 38.1 4.7 1.6e-08 34.3 3.3 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00890.1 - 3.6e-06 26.7 0.8 1.9e-05 24.3 0.2 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EOO00890.1 - 0.0016 17.9 0.6 0.0027 17.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF2305 PF10230.4 EOO00890.1 - 0.0017 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Peptidase_S15 PF02129.13 EOO00890.1 - 0.0084 15.5 0.2 0.12 11.7 0.2 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 EOO00890.1 - 0.014 14.9 0.1 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EOO00890.1 - 0.028 13.6 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF676 PF05057.9 EOO00890.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Heme_oxygenase PF01126.15 EOO00890.1 - 0.12 11.9 0.1 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase DUF1749 PF08538.5 EOO00890.1 - 0.12 11.2 0.2 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LIP PF03583.9 EOO00890.1 - 0.28 10.3 2.4 0.55 9.3 1.7 1.4 1 0 0 1 1 1 0 Secretory lipase IER PF05760.7 EOO00891.1 - 0.69 9.7 9.7 0.13 12.2 3.6 1.9 1 1 1 2 2 2 0 Immediate early response protein (IER) ChAPs PF09295.5 EOO00893.1 - 4.6e-159 529.4 0.0 5.9e-159 529.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EOO00893.1 - 1.6e-06 28.2 1.2 0.83 10.4 0.0 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EOO00893.1 - 0.00012 21.5 1.8 0.78 9.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EOO00893.1 - 0.00018 21.1 0.6 0.34 10.5 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EOO00893.1 - 0.00021 20.9 0.8 0.11 12.4 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EOO00893.1 - 0.00035 20.1 0.2 0.56 10.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EOO00893.1 - 0.00046 19.9 0.2 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EOO00893.1 - 0.004 17.5 0.4 7.7 7.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EOO00893.1 - 0.0082 16.4 0.1 6.5 7.1 0.2 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO00893.1 - 0.022 14.3 0.2 6.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EOO00893.1 - 0.029 14.3 0.1 5 7.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2007 PF09413.5 EOO00893.1 - 0.072 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) 60KD_IMP PF02096.15 EOO00894.1 - 6.7e-24 84.6 9.2 6.7e-24 84.6 6.4 2.7 2 1 0 2 2 2 1 60Kd inner membrane protein Glyco_transf_21 PF13506.1 EOO00895.1 - 1.6e-14 53.5 0.2 0.00021 20.6 0.0 3.4 2 1 1 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EOO00895.1 - 6.5e-14 52.2 0.0 2e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EOO00895.1 - 0.086 12.5 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Amino_oxidase PF01593.19 EOO00896.1 - 4.1e-45 154.6 2.6 1.9e-26 93.1 0.9 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 EOO00896.1 - 1.8e-17 63.1 0.0 3.7e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 EOO00896.1 - 4.7e-12 45.7 1.7 4.7e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO00896.1 - 3.4e-10 39.3 0.2 1.8e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO00896.1 - 7.4e-09 34.9 0.5 1.2e-08 34.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EOO00896.1 - 1.9e-08 34.6 0.3 1.9e-06 28.0 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO00896.1 - 3.2e-08 32.9 0.1 5.7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EOO00896.1 - 7e-06 25.2 0.3 0.00068 18.6 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EOO00896.1 - 2.7e-05 24.1 0.2 6.8e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO00896.1 - 3.4e-05 23.1 1.4 5.7e-05 22.3 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO00896.1 - 4.5e-05 22.1 1.1 0.00012 20.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EOO00896.1 - 6.3e-05 23.3 0.1 0.00018 21.8 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EOO00896.1 - 0.00015 20.9 0.2 0.00023 20.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EOO00896.1 - 0.00036 19.5 1.6 0.00055 18.9 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EOO00896.1 - 0.13 11.8 1.1 0.25 10.9 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CwfJ_C_2 PF04676.9 EOO00897.1 - 1.8e-24 86.0 0.0 5.1e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EOO00897.1 - 3.9e-23 81.4 0.0 6.7e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SET_assoc PF11767.3 EOO00897.1 - 0.16 11.2 0.1 0.41 9.9 0.1 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Glyco_hydro_18 PF00704.23 EOO00898.1 - 2.3e-34 119.3 0.0 2.8e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TOM13 PF08219.6 EOO00899.1 - 5.2e-32 109.4 0.0 6.3e-32 109.1 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Glyoxalase_2 PF12681.2 EOO00900.1 - 9e-08 32.6 0.4 5.9e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EOO00900.1 - 4.8e-06 26.5 4.8 0.00012 22.0 1.6 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_zinc_N PF00107.21 EOO00901.1 - 8.8e-06 25.2 0.2 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO00901.1 - 1e-05 25.2 0.1 4e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EOO00902.1 - 8.1e-16 58.3 0.1 1.6e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO00902.1 - 0.00038 20.1 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO00902.1 - 0.0064 15.4 0.1 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein zf-C2H2 PF00096.21 EOO00903.1 - 2.6e-06 27.4 10.3 0.031 14.6 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO00903.1 - 3.3e-06 27.0 10.0 0.11 12.9 0.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EOO00903.1 - 0.0018 18.4 10.9 1.2 9.4 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EOO00903.1 - 0.0039 17.3 0.7 0.0039 17.3 0.5 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-Di19 PF05605.7 EOO00903.1 - 0.081 13.0 3.5 0.19 11.9 2.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF221 PF02714.10 EOO00905.1 - 2.7e-92 309.1 19.2 3.7e-92 308.6 13.3 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EOO00905.1 - 1.5e-37 128.6 1.1 4.3e-37 127.0 0.7 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EOO00905.1 - 1.5e-17 63.8 0.2 3e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Aldo_ket_red PF00248.16 EOO00906.1 - 2.7e-54 183.9 0.0 3.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Transferase PF02458.10 EOO00907.1 - 9.9e-30 103.3 0.0 3.6e-27 94.8 0.0 2.0 1 1 0 1 1 1 1 Transferase family Grp1_Fun34_YaaH PF01184.14 EOO00909.1 - 2.9e-13 49.5 21.1 3.3e-12 46.1 10.6 2.8 1 1 2 3 3 3 3 GPR1/FUN34/yaaH family Polyketide_cyc2 PF10604.4 EOO00910.1 - 2.7e-05 24.3 0.3 3.3e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EOO00910.1 - 0.021 14.8 0.2 0.033 14.1 0.2 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport LBR_tudor PF09465.5 EOO00910.1 - 0.15 11.7 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain SnoaL_4 PF13577.1 EOO00911.1 - 6.3e-11 42.2 0.2 8.5e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.20 EOO00912.1 - 6.8e-44 149.9 0.0 8.2e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00912.1 - 2.8e-21 75.7 0.0 3.4e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EOO00912.1 - 0.00038 20.2 0.0 0.00049 19.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EOO00912.1 - 0.0019 17.2 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peripla_BP_2 PF01497.13 EOO00912.1 - 0.016 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Pox_ser-thr_kin PF05445.6 EOO00912.1 - 0.023 13.5 0.2 0.052 12.3 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UL11 PF11094.3 EOO00912.1 - 0.025 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein YrbL-PhoP_reg PF10707.4 EOO00912.1 - 0.043 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EOO00912.1 - 0.055 12.4 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.15 EOO00912.1 - 0.062 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tannase PF07519.6 EOO00913.1 - 4.9e-148 493.7 3.9 6e-148 493.4 2.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase NDUFA12 PF05071.11 EOO00914.1 - 2.8e-27 95.2 1.3 3.6e-27 94.8 0.9 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Annexin PF00191.15 EOO00915.1 - 6.7e-73 240.5 2.0 8.8e-20 70.3 0.0 4.3 4 0 0 4 4 4 4 Annexin PolyA_pol PF01743.15 EOO00915.1 - 0.059 13.5 0.8 0.32 11.2 0.5 2.1 1 1 0 1 1 1 0 Poly A polymerase head domain Acetyltransf_11 PF13720.1 EOO00915.1 - 0.14 12.4 1.5 3.7 7.8 0.0 3.0 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Gtr1_RagA PF04670.7 EOO00916.1 - 1.6e-94 315.4 0.0 2.4e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EOO00916.1 - 5.8e-08 32.2 0.1 1.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EOO00916.1 - 1.9e-07 30.4 0.0 3.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EOO00916.1 - 2.2e-05 24.9 0.0 3.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO00916.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EOO00916.1 - 0.00057 19.3 0.2 0.013 15.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EOO00916.1 - 0.0065 15.9 0.1 0.031 13.6 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EOO00916.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EOO00916.1 - 0.013 14.1 1.2 0.29 9.7 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 EOO00916.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EOO00916.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 EOO00916.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TMA7 PF09072.5 EOO00917.1 - 3e-24 85.2 21.9 3.3e-24 85.1 15.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 MFS_1 PF07690.11 EOO00918.1 - 5e-07 28.7 7.3 4.1e-05 22.4 4.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily YibE_F PF07907.6 EOO00918.1 - 0.053 12.6 4.2 0.46 9.6 0.1 2.2 2 0 0 2 2 2 0 YibE/F-like protein DUF4083 PF13314.1 EOO00918.1 - 0.054 13.3 0.4 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF962 PF06127.6 EOO00918.1 - 0.13 12.2 0.5 0.35 10.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF962) GPI2 PF06432.6 EOO00918.1 - 1.2 8.4 6.9 0.18 11.1 1.7 1.8 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase E1-E2_ATPase PF00122.15 EOO00919.1 - 1.4e-65 220.5 2.5 2.5e-65 219.7 1.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EOO00919.1 - 3.2e-35 121.2 3.1 3.2e-35 121.2 2.2 3.1 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EOO00919.1 - 7.1e-28 98.4 0.0 8.4e-27 94.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO00919.1 - 5.9e-22 77.4 0.1 1.8e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EOO00919.1 - 6.7e-17 60.7 0.4 2.6e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EOO00919.1 - 2.5e-11 44.0 0.0 1.1e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO00919.1 - 9.8e-08 31.8 0.3 1e-05 25.2 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3733 PF12534.3 EOO00919.1 - 0.0029 16.8 0.3 0.25 10.6 0.0 2.8 2 0 0 2 2 2 1 Leucine-rich repeat containing protein 8 SurE PF01975.12 EOO00920.1 - 3.3e-30 104.8 0.0 5.4e-30 104.1 0.0 1.3 1 1 0 1 1 1 1 Survival protein SurE Dioxygenase_C PF00775.16 EOO00921.1 - 4.2e-11 42.4 0.1 6.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Catalase PF00199.14 EOO00922.1 - 3.7e-169 562.4 0.1 4.5e-169 562.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EOO00922.1 - 4.8e-17 61.5 0.0 2.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive YscO PF07321.7 EOO00922.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO A_deaminase PF00962.17 EOO00923.1 - 2.3e-38 131.9 0.0 3.2e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase NOB1_Zn_bind PF08772.6 EOO00925.1 - 8.8e-32 108.7 3.5 1.5e-31 107.9 2.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EOO00925.1 - 0.00072 19.4 16.1 0.0047 16.8 11.1 2.2 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator DUF1381 PF07129.6 EOO00925.1 - 0.028 13.8 0.6 0.081 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) zf-NADH-PPase PF09297.6 EOO00925.1 - 0.047 13.2 0.6 0.047 13.2 0.4 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2616 PF11077.3 EOO00925.1 - 0.068 12.6 0.2 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) GRA6 PF05084.8 EOO00925.1 - 0.089 12.3 3.1 0.17 11.3 2.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) RRP7 PF12923.2 EOO00925.1 - 0.15 12.1 4.7 0.3 11.1 2.8 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DZR PF12773.2 EOO00925.1 - 0.15 11.9 2.5 0.29 10.9 1.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon GMC_oxred_C PF05199.8 EOO00928.1 - 6.1e-28 97.9 0.0 1.2e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EOO00928.1 - 2.1e-26 92.7 0.0 9.9e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EOO00928.1 - 0.0017 18.2 0.0 0.0066 16.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO00928.1 - 0.0026 17.7 0.1 0.0095 15.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EOO00928.1 - 0.0054 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF1737 PF08410.5 EOO00928.1 - 0.0096 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1737) Lycopene_cycl PF05834.7 EOO00928.1 - 0.041 12.7 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 EOO00928.1 - 0.067 12.0 0.1 0.15 10.9 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EOO00928.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TPR_11 PF13414.1 EOO00929.1 - 6.8e-08 32.0 4.9 0.12 12.0 0.2 5.2 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 EOO00929.1 - 0.00034 20.5 0.1 12 6.3 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EOO00929.1 - 0.0065 16.7 3.2 14 6.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00929.1 - 1.2 9.9 10.8 34 5.2 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO00929.1 - 1.9 9.3 9.7 31 5.5 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HlyIII PF03006.15 EOO00930.1 - 8.3e-33 113.6 11.5 4.7e-31 107.9 7.9 2.0 1 1 0 1 1 1 1 Haemolysin-III related DUF4530 PF15039.1 EOO00930.1 - 0.0069 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) P5-ATPase PF12409.3 EOO00930.1 - 0.14 12.0 3.2 0.28 11.0 2.2 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter adh_short PF00106.20 EOO00932.1 - 6e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EOO00932.1 - 2.9e-12 46.5 0.2 3.5e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EOO00932.1 - 1.9e-09 37.6 1.2 2.6e-09 37.2 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00932.1 - 8.8e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO00932.1 - 4e-05 22.6 0.2 6.6e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EOO00932.1 - 0.00064 19.7 0.1 0.0026 17.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO00932.1 - 0.00076 18.8 0.1 0.0017 17.6 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EOO00932.1 - 0.0063 16.4 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EOO00932.1 - 0.0076 14.9 0.1 0.01 14.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EOO00932.1 - 0.078 13.2 0.2 0.39 11.0 0.0 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF2325 PF10087.4 EOO00932.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Methyltransf_11 PF08241.7 EOO00933.1 - 3.1e-06 27.5 0.0 5.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO00933.1 - 0.051 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.24 EOO00934.1 - 2.8e-19 69.5 0.0 8.3e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO00934.1 - 7.7e-06 26.7 0.1 6.8e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EOO00934.1 - 0.00041 20.6 0.1 0.018 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EOO00934.1 - 0.00057 20.0 0.3 0.0073 16.4 0.2 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EOO00934.1 - 0.0011 18.0 0.0 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EOO00934.1 - 0.0011 18.9 0.4 0.0037 17.2 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF1910 PF08928.5 EOO00934.1 - 0.014 15.3 0.2 0.96 9.4 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) AAA_19 PF13245.1 EOO00934.1 - 0.018 14.8 0.1 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EOO00934.1 - 0.018 14.7 0.1 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EOO00934.1 - 0.036 13.9 0.0 0.45 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EOO00934.1 - 0.042 13.7 0.2 0.18 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain BUD22 PF09073.5 EOO00935.1 - 0.12 11.4 5.8 0.13 11.2 4.0 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.8 EOO00935.1 - 0.14 11.7 6.0 0.19 11.2 4.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EOO00935.1 - 0.53 8.1 10.5 0.59 7.9 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.20 EOO00936.1 - 2.9e-34 118.4 1.4 5.2e-34 117.5 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO00936.1 - 1.8e-25 90.1 3.2 5.4e-25 88.5 2.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO00936.1 - 1.6e-18 66.9 0.5 2.3e-18 66.4 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EOO00936.1 - 0.0041 16.8 0.4 0.0061 16.2 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EOO00936.1 - 0.03 14.1 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.1 EOO00936.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.6 EOO00937.1 - 3.9e-17 62.6 9.4 3.9e-17 62.6 6.5 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein CcmD PF04995.9 EOO00937.1 - 0.053 13.2 0.1 0.053 13.2 0.1 2.7 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) DUF2269 PF10027.4 EOO00937.1 - 0.056 13.2 4.3 0.25 11.1 2.7 2.3 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF1469 PF07332.6 EOO00937.1 - 0.063 13.0 6.4 0.53 10.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Steroid_dh PF02544.11 EOO00937.1 - 0.16 11.7 3.4 1.3 8.7 0.0 2.6 2 1 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase FixP_N PF14715.1 EOO00937.1 - 0.65 9.4 3.7 1.4 8.3 0.8 2.6 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP adh_short PF00106.20 EOO00938.1 - 8.1e-18 64.8 0.1 5.1e-17 62.2 0.0 2.1 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EOO00938.1 - 1.7e-10 40.8 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO00938.1 - 0.0012 18.6 0.1 0.0017 18.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EOO00938.1 - 0.0079 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.1 EOO00938.1 - 0.0082 16.2 0.0 0.077 13.1 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Epimerase PF01370.16 EOO00938.1 - 0.0083 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EOO00939.1 - 3.6e-37 127.9 0.0 4e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad4 PF03835.10 EOO00939.1 - 0.013 14.8 0.3 0.022 14.1 0.2 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain ATP_bind_1 PF03029.12 EOO00940.1 - 3.7e-77 259.0 0.0 4.8e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EOO00940.1 - 5e-06 25.4 0.1 0.0086 14.8 0.0 2.4 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 EOO00940.1 - 1.2e-05 24.8 0.1 0.00074 18.9 0.0 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EOO00940.1 - 4.4e-05 23.6 0.0 0.00017 21.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EOO00940.1 - 0.0003 20.7 0.0 0.00083 19.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EOO00940.1 - 0.00047 20.6 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EOO00940.1 - 0.00078 18.9 0.5 0.0027 17.1 0.4 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EOO00940.1 - 0.00086 19.1 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO00940.1 - 0.00094 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EOO00940.1 - 0.0014 19.4 1.0 0.0041 17.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain NB-ARC PF00931.17 EOO00940.1 - 0.0021 16.9 0.2 0.006 15.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 EOO00940.1 - 0.0021 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Arf PF00025.16 EOO00940.1 - 0.0023 17.1 0.0 0.58 9.3 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family NACHT PF05729.7 EOO00940.1 - 0.003 17.2 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EOO00940.1 - 0.0039 16.7 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EOO00940.1 - 0.0054 16.0 0.1 0.18 11.0 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.17 EOO00940.1 - 0.011 15.2 0.0 0.036 13.5 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 EOO00940.1 - 0.011 14.4 2.6 1.4 7.5 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.4 EOO00940.1 - 0.015 14.7 0.0 0.47 9.9 0.0 2.9 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EOO00940.1 - 0.016 14.6 0.1 0.14 11.6 0.0 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EOO00940.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EOO00940.1 - 0.023 15.0 0.2 3.2 8.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EOO00940.1 - 0.034 13.5 0.4 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase PRK PF00485.13 EOO00940.1 - 0.057 12.9 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Methyltransf_32 PF13679.1 EOO00940.1 - 0.079 12.6 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CbiA PF01656.18 EOO00940.1 - 0.08 12.3 0.6 0.17 11.2 0.0 1.8 2 1 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 EOO00940.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EOO00940.1 - 0.11 12.8 1.9 0.54 10.5 0.0 2.7 2 2 0 2 2 2 0 AAA domain SRPRB PF09439.5 EOO00940.1 - 0.11 11.6 0.7 8.7 5.5 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 EOO00940.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2346 PF09803.4 EOO00940.1 - 0.14 11.9 3.1 0.4 10.5 2.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) BUD22 PF09073.5 EOO00940.1 - 0.28 10.1 14.2 0.42 9.6 9.9 1.1 1 0 0 1 1 1 0 BUD22 U1snRNP70_N PF12220.3 EOO00940.1 - 1.1 9.6 6.7 0.41 11.0 2.7 1.8 2 0 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2457 PF10446.4 EOO00940.1 - 2.4 6.7 18.2 3.3 6.3 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EOO00940.1 - 2.9 6.2 14.9 3.9 5.8 10.3 1.1 1 0 0 1 1 1 0 Daxx Family PLDc_2 PF13091.1 EOO00941.1 - 1.8e-14 53.5 0.0 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EOO00941.1 - 5.3e-08 32.4 1.8 0.016 14.9 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif FTR1 PF03239.9 EOO00942.1 - 3e-60 203.7 5.6 1.8e-58 197.9 3.9 2.0 1 1 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.3 EOO00942.1 - 0.0058 16.5 0.4 0.0058 16.5 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3180) DUF4231 PF14015.1 EOO00942.1 - 1.2 9.1 5.0 0.22 11.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CPSase_L_D2 PF02786.12 EOO00943.1 - 3e-65 219.4 0.2 4.4e-65 218.9 0.1 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EOO00943.1 - 6.2e-36 122.8 0.4 1.4e-35 121.6 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EOO00943.1 - 2.2e-13 50.3 0.1 5.1e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EOO00943.1 - 7.2e-11 41.8 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EOO00943.1 - 2.8e-10 39.4 0.0 0.00016 20.5 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EOO00943.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EOO00943.1 - 0.0017 17.5 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EOO00943.1 - 0.0064 16.3 0.0 0.027 14.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EOO00943.1 - 0.0068 15.9 0.0 0.042 13.3 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain CagZ PF09053.5 EOO00944.1 - 0.065 12.5 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 CagZ AIG1 PF04548.11 EOO00944.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Sdh_cyt PF01127.17 EOO00945.1 - 3.4e-20 72.0 4.3 4.4e-20 71.7 3.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SLT_L PF14718.1 EOO00945.1 - 0.035 13.8 0.1 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain Pkinase PF00069.20 EOO00946.1 - 1.5e-54 184.8 0.0 2.7e-54 184.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO00946.1 - 1.1e-23 83.6 0.1 7.5e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EOO00946.1 - 0.0063 15.3 0.1 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EOO00946.1 - 0.017 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EOO00946.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EOO00946.1 - 0.06 13.0 0.8 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 EOO00948.1 - 1e-62 212.2 19.5 3.4e-56 190.7 6.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO00948.1 - 7.3e-24 84.1 20.5 2e-21 76.1 7.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO00948.1 - 4.2e-05 22.1 3.0 4.2e-05 22.1 2.1 3.3 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EOO00948.1 - 0.00085 19.0 0.1 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 MFS_1 like family NmrA PF05368.8 EOO00950.1 - 7.6e-53 179.1 0.3 9.2e-53 178.8 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO00950.1 - 1.5e-13 51.2 0.1 5.9e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EOO00950.1 - 1.7e-06 27.2 0.1 4.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EOO00950.1 - 3.3e-06 26.0 0.0 4.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EOO00950.1 - 0.0027 17.1 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EOO00950.1 - 0.0085 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain DXP_reductoisom PF02670.11 EOO00950.1 - 0.04 14.4 0.4 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EOO00950.1 - 0.055 13.3 0.2 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-C2H2 PF00096.21 EOO00951.1 - 0.0018 18.5 0.8 0.0018 18.5 0.5 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type DZR PF12773.2 EOO00951.1 - 0.011 15.5 0.4 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 EOO00951.1 - 0.023 15.0 1.2 0.023 15.0 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 EOO00951.1 - 0.028 14.0 0.7 0.046 13.3 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Terminase_GpA PF05876.7 EOO00951.1 - 0.037 12.3 0.4 0.048 12.0 0.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_5 PF13719.1 EOO00951.1 - 0.039 13.5 2.3 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EOO00951.1 - 0.046 13.4 2.3 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.1 EOO00951.1 - 0.062 12.5 1.4 0.15 11.2 1.0 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Tmemb_55A PF09788.4 EOO00951.1 - 0.076 12.1 0.3 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A zf-Di19 PF05605.7 EOO00951.1 - 0.11 12.6 2.2 0.22 11.6 0.7 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.6 EOO00951.1 - 0.2 11.3 1.5 0.51 10.0 1.0 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 EOO00951.1 - 0.42 11.0 2.7 2.7 8.4 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 EOO00951.1 - 1.3 8.7 4.2 8.6 6.1 0.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SEP PF08059.8 EOO00952.1 - 7.5e-26 90.2 0.0 1.9e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EOO00952.1 - 5.9e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 EOO00952.1 - 1.2e-10 40.7 0.4 1.9e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain Glycos_transf_2 PF00535.21 EOO00953.1 - 4.6e-35 120.7 0.0 5.5e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EOO00953.1 - 2.5e-15 56.8 0.0 4.1e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EOO00953.1 - 1e-09 37.8 0.0 1.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EOO00953.1 - 2.3e-06 26.9 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EOO00953.1 - 0.053 13.8 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S9 PF00326.16 EOO00954.1 - 1.7e-43 148.3 0.0 2.4e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EOO00954.1 - 2.2e-10 40.4 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO00954.1 - 3.7e-10 40.0 0.0 6.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EOO00954.1 - 8.9e-06 25.5 0.0 8.5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.7 EOO00954.1 - 1.2e-05 24.7 0.1 0.1 12.2 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.13 EOO00954.1 - 0.00021 20.6 0.0 0.00076 18.8 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EOO00954.1 - 0.00045 19.7 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EOO00954.1 - 0.00081 18.8 0.0 0.096 12.0 0.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.5 EOO00954.1 - 0.00082 18.3 0.0 0.0019 17.1 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 EOO00954.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EOO00954.1 - 0.085 12.3 0.0 0.75 9.3 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EOO00954.1 - 0.1 12.5 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Ribosomal_L12 PF00542.14 EOO00955.1 - 0.046 13.7 0.8 0.097 12.6 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain DUF2854 PF11016.3 EOO00955.1 - 0.15 11.5 0.3 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) HR1 PF02185.11 EOO00955.1 - 0.26 11.0 3.4 2.7 7.8 2.0 2.1 1 1 1 2 2 2 0 Hr1 repeat MFS_1 PF07690.11 EOO00957.1 - 3.5e-32 111.4 27.9 3.5e-32 111.4 19.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily RhoGAP PF00620.22 EOO00958.1 - 5e-17 61.9 0.0 1.3e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain DEAD PF00270.24 EOO00959.1 - 2.5e-41 141.0 0.4 6.2e-41 139.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO00959.1 - 4.2e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EOO00959.1 - 0.0096 15.2 0.5 0.017 14.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 EOO00959.1 - 0.013 15.0 0.5 0.03 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EOO00959.1 - 0.016 14.9 0.2 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EOO00959.1 - 0.024 14.4 0.1 0.065 13.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EOO00959.1 - 0.048 13.4 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EOO00959.1 - 0.11 12.6 1.0 0.5 10.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EOO00959.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Acetyltransf_7 PF13508.1 EOO00960.1 - 4e-07 30.0 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO00960.1 - 5e-07 29.6 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EOO00960.1 - 0.00097 19.2 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EOO00960.1 - 0.033 14.0 0.1 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EOO00961.1 - 1.5e-25 90.3 0.0 1.9e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00961.1 - 1.2e-09 38.0 0.0 4.9e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO00961.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3449 PF11931.3 EOO00963.1 - 7.6e-72 240.9 3.7 8.3e-72 240.8 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EOO00963.1 - 2.3e-10 40.2 2.8 8.6e-08 32.1 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EOO00963.1 - 2.7e-10 40.1 2.4 7e-08 32.4 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 EOO00963.1 - 8.5e-10 37.9 0.1 1.8e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.2 EOO00963.1 - 0.00063 19.8 0.7 0.019 15.0 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EOO00963.1 - 0.011 15.3 0.4 0.011 15.3 0.2 2.6 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.1 EOO00963.1 - 0.14 12.5 3.8 6 7.4 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EOO00963.1 - 5.7 7.4 5.5 16 6.0 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 EOO00965.1 - 4.4e-26 91.7 0.0 9.2e-26 90.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_7 PF00840.15 EOO00966.1 - 1.4e-211 702.4 26.7 1.8e-211 702.1 18.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EOO00966.1 - 2.9e-13 49.2 11.9 2.9e-13 49.2 8.3 4.9 5 1 0 5 5 5 1 Fungal cellulose binding domain MFS_1 PF07690.11 EOO00968.1 - 1.6e-21 76.4 31.8 1.6e-21 76.4 22.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily PRTase_2 PF15609.1 EOO00968.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase PD40 PF07676.7 EOO00969.1 - 7.2e-39 130.8 22.5 4.8e-07 29.3 0.1 9.6 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EOO00969.1 - 1.2e-14 53.6 1.5 0.017 13.7 0.0 7.4 4 2 3 7 7 7 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipocalin_3 PF12702.2 EOO00969.1 - 0.12 12.4 0.7 89 3.2 0.0 4.2 4 1 1 5 5 5 0 Lipocalin-like MFS_1 PF07690.11 EOO00970.1 - 5.6e-18 64.7 52.1 2.7e-16 59.2 33.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SGS PF05002.10 EOO00971.1 - 8.9e-27 92.6 4.9 3.1e-26 90.9 3.4 2.0 1 0 0 1 1 1 1 SGS domain TPR_11 PF13414.1 EOO00971.1 - 7.4e-10 38.3 5.2 2.1e-07 30.4 0.9 2.5 2 0 0 2 2 2 2 TPR repeat CS PF04969.11 EOO00971.1 - 2.7e-07 31.0 0.0 4.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.12 EOO00971.1 - 4.3e-07 29.3 4.6 0.11 12.4 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EOO00971.1 - 7.5e-06 25.3 3.0 1.4 8.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EOO00971.1 - 0.00011 22.7 9.1 0.00091 19.8 3.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EOO00971.1 - 0.0016 18.7 6.0 0.0063 16.8 0.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EOO00971.1 - 0.0035 17.4 1.3 0.015 15.4 0.6 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EOO00971.1 - 0.014 15.1 1.1 5.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EOO00971.1 - 0.039 13.8 3.3 0.33 10.9 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EOO00971.1 - 0.26 11.8 5.8 25 5.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO00971.1 - 0.47 11.2 6.6 11 6.9 1.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_M49 PF03571.10 EOO00972.1 - 1.2e-70 238.1 0.0 1.3e-63 214.9 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 PAN_4 PF14295.1 EOO00973.1 - 2e-07 30.5 0.1 6.4e-07 28.9 0.1 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EOO00973.1 - 5.3e-05 22.9 0.1 0.00019 21.1 0.1 2.0 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EOO00973.1 - 0.036 13.6 0.4 0.11 12.1 0.3 1.9 1 0 0 1 1 1 0 PAN-like domain Transformer PF06495.6 EOO00973.1 - 0.063 13.1 0.1 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1546 PF07571.8 EOO00975.1 - 9.4e-29 99.3 0.0 1.9e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EOO00975.1 - 8.5e-22 76.8 0.0 2.2e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EOO00975.1 - 0.0024 17.9 0.1 0.0054 16.8 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EOO00975.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TauD PF02668.11 EOO00976.1 - 2.1e-53 181.6 0.0 2.5e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EOO00976.1 - 0.015 15.8 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 EOO00976.1 - 0.026 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 CsiD PhyH PF05721.8 EOO00976.1 - 0.13 12.2 0.1 0.79 9.7 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CFEM PF05730.6 EOO00979.1 - 1.2e-08 34.5 6.0 2.2e-08 33.8 4.2 1.4 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 EOO00979.1 - 2.1 7.6 11.4 2.5 7.4 7.9 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EOO00979.1 - 4.4 7.0 5.8 5.5 6.7 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 EOO00979.1 - 6.9 5.2 12.3 8.4 4.9 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.13 EOO00980.1 - 9e-44 149.2 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EOO00980.1 - 0.00085 19.5 0.3 0.00085 19.5 0.2 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO00980.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Cu-oxidase_2 PF07731.9 EOO00981.1 - 3.1e-40 136.8 2.0 7.4e-38 129.1 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EOO00981.1 - 2.3e-37 128.3 1.1 1e-34 119.7 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EOO00981.1 - 6.8e-19 67.7 4.8 2.8e-15 56.0 0.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Nop10p PF04135.7 EOO00983.1 - 1.9e-18 65.9 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Abhydrolase_6 PF12697.2 EOO00984.1 - 6.5e-22 78.5 0.0 1.2e-21 77.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO00984.1 - 8.4e-08 32.0 0.0 9.6e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold UbiA PF01040.13 EOO00986.1 - 9.6e-31 106.9 27.9 1.5e-30 106.2 19.3 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Med3 PF11593.3 EOO00986.1 - 0.48 9.6 10.5 0.64 9.1 7.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_tranf_2_3 PF13641.1 EOO00987.1 - 5.5e-17 62.3 0.0 6.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EOO00987.1 - 1.3e-09 38.0 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EOO00987.1 - 3.5e-07 29.6 0.0 1.5e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EOO00987.1 - 9.2e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF570 PF04489.8 EOO00987.1 - 0.041 12.2 0.0 0.068 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF570) p450 PF00067.17 EOO00988.1 - 8.3e-47 159.7 0.0 1.1e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YvrJ PF12841.2 EOO00988.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 YvrJ protein family Chitin_bind_3 PF03067.10 EOO00989.1 - 9.4e-11 42.2 0.3 1.4e-10 41.7 0.2 1.3 1 0 0 1 1 1 1 Chitin binding domain Herpes_LMP1 PF05297.6 EOO00989.1 - 5.2 5.8 17.6 7 5.4 12.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Amidoligase_2 PF12224.3 EOO00990.1 - 2.5e-24 86.2 0.0 1.9e-15 57.2 0.0 2.2 1 1 1 2 2 2 2 Putative amidoligase enzyme Prenyltrans PF00432.16 EOO00991.1 - 5.4e-27 93.0 8.4 7e-09 35.1 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EOO00991.1 - 9.6e-22 77.5 1.3 1.7e-14 54.1 0.1 4.5 4 1 0 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EOO00991.1 - 3.7e-21 75.1 1.2 1.7e-15 56.9 0.1 5.3 5 2 1 6 6 6 3 Prenyltransferase-like Pec_lyase PF09492.5 EOO00991.1 - 1.3e-05 24.5 1.1 0.22 10.6 0.0 4.1 4 1 1 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EOO00991.1 - 0.011 15.0 0.2 0.41 9.8 0.0 3.1 2 1 1 3 3 3 0 A-macroglobulin complement component Sugar_tr PF00083.19 EOO00992.1 - 2.5e-46 158.2 10.4 2.8e-46 158.0 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EOO00992.1 - 5.2e-09 34.9 4.4 5.2e-09 34.9 3.1 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 EOO00992.1 - 1.8e-06 26.9 11.5 2.9e-06 26.2 7.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EOO00995.1 - 4e-54 183.3 0.0 4.8e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.21 EOO00996.1 - 5.9e-09 35.5 0.3 1.1e-08 34.6 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO00996.1 - 5.2e-08 32.6 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_4 PF08386.5 EOO00997.1 - 1e-20 73.5 0.2 2.5e-20 72.2 0.1 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EOO00997.1 - 2.8e-13 49.9 0.1 2.6e-07 30.4 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO00997.1 - 3.5e-09 36.9 0.0 3.2e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO00997.1 - 9.2e-05 22.2 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family ADH_N PF08240.7 EOO00998.1 - 1.6e-08 34.2 0.1 1.8e-07 30.8 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO00998.1 - 3.2e-05 23.4 0.1 7.2e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO00998.1 - 0.00011 23.1 0.0 0.0014 19.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Dioxygenase_C PF00775.16 EOO01000.1 - 9.7e-08 31.4 0.7 1.6e-06 27.5 0.5 2.7 1 1 0 1 1 1 1 Dioxygenase CoatB PF10389.4 EOO01000.1 - 0.15 11.9 0.9 0.33 10.8 0.6 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B MFS_1 PF07690.11 EOO01001.1 - 1.6e-38 132.3 30.1 1.6e-38 132.3 20.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1688 PF07958.6 EOO01002.1 - 7e-169 561.7 0.0 4.9e-168 559.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) OTT_1508_deam PF14441.1 EOO01003.1 - 0.00014 21.7 0.2 0.00017 21.4 0.1 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase PLU-1 PF08429.6 EOO01004.1 - 3e-102 341.9 15.1 1.5e-98 329.8 10.9 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EOO01004.1 - 8.9e-41 138.7 0.1 2.3e-40 137.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EOO01004.1 - 5.1e-26 90.3 0.1 1.7e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EOO01004.1 - 9e-18 63.7 26.4 1.4e-10 40.6 4.3 2.8 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EOO01004.1 - 6.3e-15 54.4 1.2 1.5e-14 53.1 0.8 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EOO01004.1 - 0.0014 18.7 6.3 0.38 10.9 1.2 2.7 2 0 0 2 2 2 2 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EOO01004.1 - 0.01 15.5 1.3 0.01 15.5 0.9 3.3 2 1 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EOO01004.1 - 0.025 14.2 11.0 0.64 9.7 2.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EOO01004.1 - 0.49 10.2 19.5 2.1 8.2 3.9 2.5 2 0 0 2 2 2 0 Ring finger domain zf-PHD-like PF15446.1 EOO01004.1 - 0.93 8.7 13.0 0.38 10.0 1.2 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EOO01004.1 - 2.1 7.7 11.9 0.17 11.2 1.0 2.9 2 0 0 2 2 2 0 PHD-finger Glyco_hydro_28 PF00295.12 EOO01005.1 - 1.4e-28 99.8 5.2 1.8e-28 99.4 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sugar_tr PF00083.19 EOO01006.1 - 3.3e-98 329.2 21.9 3.7e-98 329.0 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01006.1 - 6.8e-29 100.6 28.9 1.5e-22 79.8 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01006.1 - 0.00034 19.1 33.9 0.0024 16.3 2.7 3.9 2 2 1 4 4 4 2 MFS/sugar transport protein P2_Phage_GpR PF06891.6 EOO01008.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) p450 PF00067.17 EOO01009.1 - 1.2e-07 30.6 0.0 1.3e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1180 PF06679.7 EOO01010.1 - 0.75 9.6 2.6 1.2 8.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FAD_binding_3 PF01494.14 EOO01011.1 - 1.3e-10 40.9 0.1 6e-09 35.4 0.1 2.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EOO01011.1 - 7.2e-06 26.3 0.1 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO01011.1 - 7.6e-06 25.0 0.3 0.011 14.6 0.1 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO01011.1 - 7e-05 22.7 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EOO01011.1 - 0.001 18.0 0.0 0.005 15.8 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EOO01011.1 - 0.0045 16.7 0.1 0.0099 15.6 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SecA_SW PF07516.8 EOO01011.1 - 0.0069 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 SecA Wing and Scaffold domain TrkA_N PF02254.13 EOO01011.1 - 0.013 15.5 0.1 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EOO01011.1 - 0.018 15.0 0.2 0.028 14.4 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EOO01011.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EOO01011.1 - 0.058 13.2 0.1 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EOO01011.1 - 0.062 12.7 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EOO01011.1 - 0.088 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 EOO01011.1 - 0.11 11.5 0.0 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EOO01011.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 EOO01012.1 - 3.4e-38 131.3 0.0 4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 EOO01013.1 - 1.2e-14 54.0 0.0 1.7e-14 53.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EOO01013.1 - 0.00098 18.0 0.0 0.0066 15.3 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EOO01013.1 - 0.0023 17.6 0.1 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EOO01013.1 - 0.0029 17.0 0.4 0.0048 16.3 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EOO01013.1 - 0.0029 17.5 0.3 0.0065 16.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EOO01013.1 - 0.0045 17.0 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EOO01013.1 - 0.0076 16.1 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO01013.1 - 0.012 14.4 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EOO01013.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CNF1 PF05785.7 EOO01013.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Pyr_redox PF00070.22 EOO01013.1 - 0.095 13.1 0.7 0.17 12.2 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO01013.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.21 EOO01014.1 - 1.2e-19 70.0 0.0 2.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO01014.1 - 1.6e-10 41.9 0.0 2.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EOO01014.1 - 6.1e-06 26.3 0.0 9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_C PF02080.16 EOO01014.1 - 0.0022 17.5 0.1 0.08 12.5 0.0 2.3 2 0 0 2 2 2 1 TrkA-C domain Semialdhyde_dh PF01118.19 EOO01014.1 - 0.0045 17.2 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EOO01014.1 - 0.059 13.2 0.4 0.22 11.4 0.2 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.16 EOO01014.1 - 0.071 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aminotran_3 PF00202.16 EOO01015.1 - 1.7e-50 171.8 0.2 2e-50 171.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_1 PF00232.13 EOO01016.1 - 5.5e-72 242.4 0.1 6.6e-70 235.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Aldo_ket_red PF00248.16 EOO01017.1 - 7.4e-28 97.1 0.0 9.6e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EOO01018.1 - 1e-15 57.6 0.0 1.7e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01018.1 - 8.3e-13 48.7 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO01018.1 - 9.3e-08 31.7 0.0 9.2e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO01018.1 - 0.00038 19.4 0.1 0.00088 18.2 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EOO01018.1 - 0.029 14.6 0.1 0.045 14.0 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EOO01018.1 - 0.03 13.9 0.1 0.064 12.9 0.0 1.7 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 EOO01018.1 - 0.031 14.1 0.3 0.077 12.9 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EOO01018.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EOO01018.1 - 0.075 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Sugar_tr PF00083.19 EOO01019.1 - 1.1e-106 357.1 19.6 1.3e-106 356.9 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01019.1 - 1.4e-27 96.4 34.2 5.4e-21 74.7 9.2 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EOO01019.1 - 5.5e-08 31.4 1.2 5.5e-08 31.4 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 EOO01019.1 - 1.6 8.2 15.6 0.6 9.5 1.9 3.0 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 EOO01019.1 - 1.7 8.4 8.4 3 7.7 2.3 3.1 3 0 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 EOO01021.1 - 4.4e-100 335.3 18.7 1.2e-93 314.1 10.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01021.1 - 2.5e-21 75.7 26.0 1.2e-20 73.5 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01021.1 - 9.9e-07 27.4 24.4 0.00027 19.4 9.0 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1469 PF07332.6 EOO01021.1 - 1.6 8.4 0.0 1.6 8.4 0.0 4.1 2 2 3 5 5 5 0 Protein of unknown function (DUF1469) ADH_N PF08240.7 EOO01023.1 - 1.1e-16 60.5 0.0 3e-16 59.1 0.0 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO01023.1 - 3e-08 33.2 0.2 6.4e-07 28.9 0.2 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 EOO01023.1 - 0.037 13.5 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 Cupin domain FAD_binding_2 PF00890.19 EOO01023.1 - 0.064 12.0 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EOO01023.1 - 0.078 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 EOO01024.1 - 0.0041 17.1 0.5 0.017 15.1 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO01025.1 - 5.8e-14 51.9 0.0 8.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01025.1 - 0.00019 21.4 0.0 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO01025.1 - 0.12 11.7 0.1 1.1 8.6 0.0 2.3 2 2 0 2 2 2 0 NAD dependent epimerase/dehydratase family AA_permease_2 PF13520.1 EOO01026.1 - 8.9e-36 123.3 33.9 1.2e-35 122.9 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.16 EOO01027.1 - 8.7e-57 192.0 0.0 9.9e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.18 EOO01028.1 - 3.1e-17 62.3 2.5 3.1e-17 62.3 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EOO01028.1 - 1e-08 34.9 0.1 2.6e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.14 EOO01029.1 - 1.2e-12 47.5 0.1 1.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EOO01029.1 - 6.4e-08 31.8 0.1 9.8e-07 27.9 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO01029.1 - 1.4e-06 28.2 0.2 2.8e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EOO01029.1 - 3.8e-05 22.7 0.1 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EOO01029.1 - 0.00023 21.5 0.3 0.00062 20.1 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO01029.1 - 0.00061 19.7 0.5 0.0012 18.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO01029.1 - 0.0027 16.8 0.1 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO01029.1 - 0.017 13.9 3.9 0.038 12.8 2.8 1.5 1 1 1 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 EOO01029.1 - 0.03 13.4 0.4 0.38 9.7 0.1 2.6 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EOO01029.1 - 0.048 13.3 0.4 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EOO01029.1 - 0.058 12.2 0.7 0.087 11.6 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EOO01029.1 - 0.064 13.3 0.1 0.22 11.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO01029.1 - 0.2 10.0 1.3 0.28 9.5 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EOO01029.1 - 0.21 11.2 1.1 0.45 10.1 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HpcH_HpaI PF03328.9 EOO01030.1 - 1.8e-34 118.5 0.1 2.1e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.11 EOO01032.1 - 2.5e-32 112.0 27.6 2.5e-32 112.0 19.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_C PF00032.12 EOO01032.1 - 0.032 14.4 5.5 6.6 7.0 0.1 3.8 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD RseC_MucC PF04246.7 EOO01032.1 - 0.24 10.9 7.6 0.36 10.3 0.3 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Wzz PF02706.10 EOO01032.1 - 0.41 10.4 3.0 10 5.9 0.2 2.5 1 1 1 2 2 2 0 Chain length determinant protein ADH_zinc_N PF00107.21 EOO01033.1 - 3.9e-19 68.4 0.0 5.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO01033.1 - 3e-17 62.3 3.6 4.8e-17 61.7 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO01033.1 - 0.00029 21.7 0.0 0.00056 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PIN PF01850.16 EOO01033.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 PIN domain WD40 PF00400.27 EOO01034.1 - 1.3e-14 53.4 7.6 0.00037 20.2 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat RPE65 PF03055.10 EOO01035.1 - 5.4e-128 427.6 0.0 6.5e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.1 EOO01035.1 - 5.3e-25 87.7 1.3 1.6e-24 86.2 0.2 2.3 2 0 0 2 2 2 1 SnoaL-like domain PPR_2 PF13041.1 EOO01036.1 - 0.031 14.2 0.3 0.11 12.4 0.0 2.1 3 0 0 3 3 3 0 PPR repeat family PPR_3 PF13812.1 EOO01036.1 - 0.084 13.1 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR PF01535.15 EOO01036.1 - 0.25 11.3 2.4 6.3 7.0 0.2 3.7 3 1 0 3 3 3 0 PPR repeat Epimerase PF01370.16 EOO01037.1 - 2.1e-20 73.1 0.1 1.2e-19 70.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO01037.1 - 5.2e-11 41.7 0.0 6.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EOO01037.1 - 2.1e-08 33.3 0.0 7.7e-07 28.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EOO01037.1 - 1.8e-07 31.3 0.0 6.2e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EOO01037.1 - 2.3e-07 30.8 0.1 5.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EOO01037.1 - 0.00012 21.0 0.4 0.099 11.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EOO01037.1 - 0.00052 19.3 0.0 0.0016 17.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EOO01037.1 - 0.003 16.5 0.0 0.0068 15.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EOO01037.1 - 0.016 14.8 0.1 0.054 13.1 0.1 1.9 1 1 0 1 1 1 0 KR domain Abhydrolase_4 PF08386.5 EOO01038.1 - 2.8e-18 65.6 0.0 5.4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EOO01038.1 - 5.4e-18 65.3 0.0 3.8e-13 49.5 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO01038.1 - 5.1e-11 42.8 0.0 1.3e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO01038.1 - 1.7e-05 24.5 0.0 0.00019 21.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease PF00324.16 EOO01039.1 - 1e-117 393.4 32.9 1.2e-117 393.2 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO01039.1 - 2.7e-30 105.2 36.8 3.3e-30 104.9 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease GRAM PF02893.15 EOO01040.1 - 2.1e-29 100.8 2.2 1.7e-16 59.4 0.1 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EOO01040.1 - 1.9e-25 89.2 0.0 3.4e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EOO01040.1 - 6.1e-12 45.6 0.3 2.1e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 EOO01040.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EOO01040.1 - 0.00018 20.2 0.0 0.0013 17.4 0.0 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 EOO01040.1 - 0.00041 20.1 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EOO01040.1 - 0.0081 16.4 0.1 0.049 13.8 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain 2-Hacid_dh_C PF02826.14 EOO01041.1 - 4e-44 149.8 0.0 9.7e-30 103.0 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EOO01041.1 - 0.00018 21.5 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_2 PF03446.10 EOO01041.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EOO01041.1 - 0.036 14.4 0.0 0.091 13.2 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EOO01041.1 - 0.072 12.7 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EOO01041.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain NUT_N PF12881.2 EOO01041.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 NUT protein N terminus Beta_helix PF13229.1 EOO01042.1 - 2.2e-12 46.9 18.0 3.7e-10 39.7 3.9 3.1 1 1 2 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.1 EOO01042.1 - 2.6e-07 29.8 0.0 6.4e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Chondroitinase B NosD PF05048.8 EOO01042.1 - 2.3e-06 26.9 10.9 0.00056 19.1 1.0 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 EOO01042.1 - 1.6e-05 24.1 0.6 1.6e-05 24.1 0.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) DUF2470 PF10615.4 EOO01043.1 - 1.4e-18 66.9 0.2 2e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) ATP-synt_C PF00137.16 EOO01044.1 - 2.9e-31 107.1 30.7 1.6e-18 66.3 9.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EOO01044.1 - 0.036 13.6 0.7 0.036 13.6 0.5 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EOO01044.1 - 0.11 11.6 2.0 4.7 6.3 0.3 2.1 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 EOO01044.1 - 8.4 6.0 11.0 1.1 8.8 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF3115 PF11312.3 EOO01045.1 - 2.3e-84 282.9 0.0 3e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Sugar_tr PF00083.19 EOO01046.1 - 2.7e-69 233.9 17.6 3e-69 233.7 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01046.1 - 1.3e-24 86.5 44.0 7.8e-24 84.0 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO01046.1 - 0.018 13.2 6.2 0.0047 15.1 2.1 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 EOO01046.1 - 0.14 11.2 6.6 0.17 11.0 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF554) DUF2150 PF09920.4 EOO01047.1 - 0.01 15.4 1.0 0.023 14.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Ric8 PF10165.4 EOO01047.1 - 0.04 12.7 0.7 1.1 8.0 0.4 2.5 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn LSM PF01423.17 EOO01048.1 - 7.1e-15 54.3 0.8 8.9e-15 53.9 0.6 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EOO01048.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 PhnA protein ICE2 PF08426.5 EOO01049.1 - 1.3e-145 485.2 8.7 1.5e-145 484.9 6.0 1.0 1 0 0 1 1 1 1 ICE2 Ribosomal_L7Ae PF01248.21 EOO01050.1 - 1.6e-26 91.6 0.1 2e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mur_ligase_M PF08245.7 EOO01051.1 - 3.2e-08 33.8 0.0 6.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain DUF218 PF02698.12 EOO01051.1 - 6e-06 25.8 0.2 0.00012 21.5 0.2 2.4 1 1 0 1 1 1 1 DUF218 domain Mur_ligase_C PF02875.16 EOO01051.1 - 0.061 13.3 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain ERG4_ERG24 PF01222.12 EOO01052.1 - 2.2e-134 448.2 22.1 2.7e-134 447.9 15.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Syja_N PF02383.13 EOO01053.1 - 9.5e-98 326.8 0.0 1.5e-97 326.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EOO01053.1 - 4.3e-33 113.1 0.1 1e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Inositol phosphatase Pkinase PF00069.20 EOO01054.1 - 1.3e-06 27.7 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01054.1 - 0.031 13.3 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Transketolase_N PF00456.16 EOO01056.1 - 7.2e-151 501.6 0.0 1.1e-150 501.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EOO01056.1 - 5.1e-44 149.8 0.0 8.2e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EOO01056.1 - 1.2e-11 44.6 0.0 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain COesterase PF00135.23 EOO01057.1 - 1.2e-87 294.9 0.0 1.3e-87 294.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO01057.1 - 3.1e-06 26.9 0.1 2.9e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold CP_ATPgrasp_1 PF04174.8 EOO01059.1 - 7.1e-76 254.9 0.0 9.6e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp CP_ATPgrasp_2 PF14403.1 EOO01059.1 - 4.2e-05 22.3 0.0 0.00041 19.1 0.0 2.4 1 1 0 1 1 1 1 Circularly permuted ATP-grasp type 2 GCS2 PF04107.8 EOO01059.1 - 6.7e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) ATP-grasp_4 PF13535.1 EOO01059.1 - 0.043 13.5 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain FliT PF05400.8 EOO01059.1 - 0.15 12.4 0.9 7.8 6.9 0.1 2.7 2 0 0 2 2 2 0 Flagellar protein FliT DUF3954 PF13128.1 EOO01059.1 - 0.2 11.1 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) TPR_14 PF13428.1 EOO01059.1 - 3.8 8.4 7.7 2.1 9.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DIOX_N PF14226.1 EOO01060.1 - 1.4e-12 48.1 0.2 3.5e-12 46.8 0.2 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO01060.1 - 8.6e-12 45.2 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_3 PF13302.1 EOO01061.1 - 6e-13 49.1 0.9 6.5e-13 49.0 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO01061.1 - 1.7e-11 44.0 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EOO01061.1 - 8.6e-09 35.5 0.1 1.1e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO01061.1 - 8.6e-05 22.4 0.1 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EOO01061.1 - 0.00081 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EOO01061.1 - 0.0028 17.3 0.0 0.0054 16.4 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EOO01061.1 - 0.073 13.1 0.1 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.15 EOO01062.1 - 1.8e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EOO01062.1 - 2.2e-07 30.5 0.0 5.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Palm_thioest PF02089.10 EOO01063.1 - 1.5e-54 184.8 0.0 1.9e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EOO01063.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HTH_18 PF12833.2 EOO01063.1 - 0.033 14.3 0.0 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF915 PF06028.6 EOO01063.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Dynamin_N PF00350.18 EOO01064.1 - 1.7e-21 76.8 0.0 6.6e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EOO01064.1 - 2.7e-06 27.3 0.0 1.4e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EOO01064.1 - 6.4e-06 25.5 0.1 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 EOO01064.1 - 0.00015 22.2 0.0 0.00092 19.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EOO01064.1 - 0.0057 16.1 0.0 0.93 8.9 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EOO01064.1 - 0.0079 15.4 0.0 0.16 11.2 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EOO01064.1 - 0.011 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EOO01064.1 - 0.034 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EOO01064.1 - 0.049 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EOO01064.1 - 0.069 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 EOO01064.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SOR_SNZ PF01680.12 EOO01064.1 - 0.093 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 SOR/SNZ family GTP_EFTU PF00009.22 EOO01064.1 - 0.13 11.6 0.2 10 5.5 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CPSF_A PF03178.10 EOO01065.1 - 1.9e-65 221.0 0.0 1.1e-63 215.2 0.0 3.2 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EOO01065.1 - 7.3e-64 215.7 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.1 EOO01065.1 - 0.13 12.5 1.1 3.3 8.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Utp12 PF04003.7 EOO01066.1 - 0.0073 16.2 1.3 1.3 8.9 0.1 2.5 2 0 0 2 2 2 1 Dip2/Utp12 Family CK2S PF15011.1 EOO01066.1 - 0.012 15.4 6.3 0.065 13.0 0.1 3.7 4 0 0 4 4 4 0 Casein Kinase 2 substrate TPR_MLP1_2 PF07926.7 EOO01066.1 - 0.29 10.8 8.9 1.4 8.6 0.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.10 EOO01066.1 - 0.29 10.8 4.3 6.1 6.5 0.2 2.7 2 0 0 2 2 2 0 Sec34-like family THOC7 PF05615.8 EOO01066.1 - 0.62 10.3 13.6 0.3 11.3 2.7 3.3 2 1 1 3 3 3 0 Tho complex subunit 7 DUF148 PF02520.12 EOO01066.1 - 0.94 9.2 6.6 0.54 10.0 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF148 DUF948 PF06103.6 EOO01066.1 - 1.5 8.7 6.1 4.7 7.1 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 EOO01066.1 - 2.2 8.6 13.1 6 7.2 1.9 3.8 4 0 0 4 4 4 0 Spectrin repeat V_ATPase_I PF01496.14 EOO01066.1 - 3.4 5.4 9.6 4.8 4.8 2.3 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.12 EOO01066.1 - 5.2 6.7 13.0 6.2 6.4 0.2 3.9 3 1 1 4 4 4 0 Prefoldin subunit Sec8_exocyst PF04048.9 EOO01066.1 - 5.3 6.6 11.6 2.2 7.8 0.6 3.1 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Spore_II_R PF09551.5 EOO01066.1 - 7.5 6.5 8.0 3.4 7.7 1.5 2.9 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF1295 PF06966.7 EOO01068.1 - 3.4e-16 59.2 0.4 4.5e-16 58.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EOO01068.1 - 0.00014 20.5 5.1 0.00054 18.6 3.5 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 EOO01068.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EOO01068.1 - 0.00083 19.4 0.2 0.00083 19.4 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EOO01068.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family adh_short PF00106.20 EOO01069.1 - 2.9e-26 92.3 0.1 4.3e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01069.1 - 1.6e-21 77.1 0.0 2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO01069.1 - 8.3e-15 54.9 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF43 PF01861.11 EOO01069.1 - 0.0094 14.9 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 CmcI PF04989.7 EOO01069.1 - 0.11 11.8 0.0 13 5.0 0.0 2.1 2 0 0 2 2 2 0 Cephalosporin hydroxylase Pro-kuma_activ PF09286.6 EOO01070.1 - 1.6e-28 99.5 0.0 2.8e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EOO01070.1 - 3.2e-05 23.2 0.1 5.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy PF03171.15 EOO01071.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EOO01071.1 - 6.2e-06 26.7 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Bromodomain PF00439.20 EOO01072.1 - 3.1e-18 65.4 0.0 6.2e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EOO01072.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain End_N_terminal PF12218.3 EOO01072.1 - 0.083 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Lyase_1 PF00206.15 EOO01073.1 - 4.7e-38 131.1 0.0 9.9e-37 126.7 0.0 2.1 1 1 1 2 2 2 2 Lyase ADSL_C PF10397.4 EOO01073.1 - 5.8e-19 67.8 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Glyoxalase_2 PF12681.2 EOO01074.1 - 9.4e-08 32.6 0.1 1.1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EOO01074.1 - 1.2e-05 25.2 0.2 5.3e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sugar_tr PF00083.19 EOO01075.1 - 2.5e-81 273.5 24.1 3.2e-81 273.2 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01075.1 - 5.5e-18 64.8 25.4 8e-12 44.5 6.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EOO01077.1 - 3.8e-05 22.5 3.3 0.00049 18.9 3.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01077.1 - 0.027 12.8 0.1 0.038 12.4 0.1 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Ycf1 PF05758.7 EOO01077.1 - 0.054 11.2 0.0 0.054 11.2 0.0 1.0 1 0 0 1 1 1 0 Ycf1 Sugar_tr PF00083.19 EOO01077.1 - 0.09 11.3 2.4 0.17 10.3 1.7 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter Neurensin PF14927.1 EOO01077.1 - 0.2 11.0 1.5 0.45 9.8 0.0 2.2 1 1 1 2 2 2 0 Neurensin TP_methylase PF00590.15 EOO01078.1 - 2.6e-21 76.2 0.0 4.4e-21 75.5 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_trans_2_3 PF13632.1 EOO01079.1 - 5.4e-41 140.4 13.2 6.7e-40 136.8 9.2 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EOO01079.1 - 4.3e-06 26.6 0.0 2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EOO01079.1 - 8.7e-06 25.5 0.1 8.6e-05 22.2 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EOO01079.1 - 0.0059 15.9 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 RhoGEF PF00621.15 EOO01080.1 - 3.3e-29 102.0 1.3 1.3e-26 93.5 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain DUF3507 PF12015.3 EOO01080.1 - 0.0042 16.6 0.0 0.0094 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) PMC2NT PF08066.7 EOO01080.1 - 1 9.6 6.7 11 6.3 0.4 4.2 4 0 0 4 4 4 0 PMC2NT (NUC016) domain DUF3584 PF12128.3 EOO01080.1 - 5.3 4.2 19.3 0.087 10.1 8.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MTP18 PF10558.4 EOO01082.1 - 2.9e-67 225.2 0.1 3.6e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) CAP59_mtransfer PF11735.3 EOO01083.1 - 2.9e-58 196.9 0.0 4.1e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SurE PF01975.12 EOO01084.1 - 8.9e-25 87.1 1.3 4.7e-20 71.7 0.1 2.1 1 1 1 2 2 2 2 Survival protein SurE LPAM_1 PF08139.7 EOO01084.1 - 0.052 13.7 2.0 0.052 13.7 1.4 2.0 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Sugar_tr PF00083.19 EOO01085.1 - 9.9e-38 129.8 27.6 1.9e-29 102.5 7.7 2.4 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01085.1 - 7.5e-09 34.7 31.9 1.5e-06 27.1 6.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1072 PF06380.6 EOO01085.1 - 0.13 11.8 3.0 0.15 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) p450 PF00067.17 EOO01086.1 - 3e-70 237.0 0.0 4.6e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EOO01086.1 - 6.2e-35 120.6 0.0 2.4e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EOO01086.1 - 3.7e-25 88.5 0.0 9.1e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EOO01086.1 - 4.5e-12 46.5 0.0 1.3e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EOO01086.1 - 0.0039 17.0 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 EOO01086.1 - 0.0044 17.0 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin domain ABC_tran PF00005.22 EOO01087.1 - 5.8e-29 101.1 0.1 6.4e-25 88.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EOO01087.1 - 8e-09 35.8 0.1 0.0005 20.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EOO01087.1 - 4.3e-08 32.6 0.0 5.7e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 EOO01087.1 - 6.7e-06 25.7 11.3 0.0059 16.0 0.0 3.2 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.1 EOO01087.1 - 0.0012 19.0 0.3 0.0096 16.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO01087.1 - 0.0061 16.5 0.3 0.014 15.4 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EOO01087.1 - 0.0091 15.5 0.8 0.027 14.0 0.6 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EOO01087.1 - 0.041 13.7 0.1 0.85 9.5 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EOO01087.1 - 0.043 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EOO01087.1 - 0.056 13.3 0.1 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.12 EOO01087.1 - 0.11 12.2 0.9 0.37 10.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Peptidase_C13 PF01650.13 EOO01088.1 - 9.2e-41 139.8 0.3 1.2e-40 139.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Sugar_tr PF00083.19 EOO01089.1 - 8e-63 212.5 14.3 8.1e-62 209.2 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01089.1 - 1.4e-18 66.7 25.1 4.9e-13 48.5 6.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.14 EOO01089.1 - 0.0061 16.6 3.8 0.019 15.0 2.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Methyltransf_23 PF13489.1 EOO01090.1 - 3.7e-06 26.7 0.1 0.00044 20.0 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain AA_permease PF00324.16 EOO01091.1 - 1.2e-92 310.7 37.1 1.4e-92 310.5 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO01091.1 - 8.5e-20 70.6 39.4 1e-19 70.4 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.26 EOO01092.1 - 2.6e-06 27.3 0.0 4.9e-05 23.2 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain BTV_NS2 PF04514.7 EOO01092.1 - 0.71 8.6 4.5 1.1 8.0 3.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 EOO01092.1 - 4 5.3 8.9 5.5 4.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EOO01092.1 - 5.5 6.1 13.8 9.3 5.4 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 EOO01092.1 - 6.4 5.7 13.9 10 5.0 9.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EOO01092.1 - 7.4 4.3 11.9 9.4 4.0 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Med4 PF10018.4 EOO01093.1 - 1.2e-41 142.2 8.6 2.5e-41 141.1 5.9 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MAP7 PF05672.6 EOO01093.1 - 0.0018 17.6 21.0 0.0036 16.6 14.5 1.5 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Dynamin_N PF00350.18 EOO01093.1 - 0.1 12.3 1.4 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Spore_coat_CotO PF14153.1 EOO01093.1 - 0.13 11.6 6.8 0.26 10.7 4.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DegQ PF08181.6 EOO01093.1 - 0.17 11.5 3.7 8 6.2 0.4 2.6 2 0 0 2 2 2 0 DegQ (SacQ) family Caldesmon PF02029.10 EOO01093.1 - 0.32 9.3 16.7 0.56 8.5 11.6 1.4 1 0 0 1 1 1 0 Caldesmon Sec34 PF04136.10 EOO01093.1 - 0.47 10.1 4.7 0.29 10.8 0.2 2.6 2 1 0 2 2 2 0 Sec34-like family AAA_11 PF13086.1 EOO01093.1 - 1.6 8.2 5.7 0.71 9.4 1.0 1.9 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EOO01093.1 - 3.1 5.5 9.0 4.5 5.0 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CAF-1_p150 PF11600.3 EOO01093.1 - 4.4 6.6 24.4 8 5.7 16.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_3_C PF01915.17 EOO01094.1 - 2e-44 151.8 0.1 2e-43 148.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EOO01094.1 - 2.9e-25 88.8 0.0 5.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cyclin_N PF00134.18 EOO01094.1 - 2e-10 40.3 0.1 3.8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sld5 PF05916.6 EOO01095.1 - 9.7e-25 86.9 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Ribosomal_60s PF00428.14 EOO01095.1 - 0.022 15.1 0.4 0.022 15.1 0.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rad4 PF03835.10 EOO01096.1 - 9e-34 115.9 2.5 9e-34 115.9 1.7 2.8 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EOO01096.1 - 2.8e-25 87.8 0.3 5.6e-25 86.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EOO01096.1 - 1.5e-20 72.4 0.2 3.5e-20 71.2 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EOO01096.1 - 1.1e-15 57.6 0.2 1.1e-15 57.6 0.1 3.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EOO01096.1 - 0.016 15.4 0.0 0.064 13.4 0.0 2.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily EF-hand_7 PF13499.1 EOO01097.1 - 4.9e-16 58.6 0.3 8e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EOO01097.1 - 1.6e-12 46.2 0.5 4e-05 23.1 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EOO01097.1 - 4e-11 42.6 0.0 3.3e-05 23.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EOO01097.1 - 6.1e-11 40.8 0.4 0.00051 19.1 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EOO01097.1 - 3e-07 29.9 1.4 0.00078 19.0 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EOO01097.1 - 0.034 13.5 2.8 2.2 7.7 0.7 2.8 2 0 0 2 2 2 0 EF hand COesterase PF00135.23 EOO01098.1 - 0.036 12.7 1.3 0.041 12.5 0.9 1.1 1 0 0 1 1 1 0 Carboxylesterase family GlgS PF08971.6 EOO01098.1 - 0.074 12.9 0.2 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycogen synthesis protein R3H-assoc PF13902.1 EOO01099.1 - 6.7e-17 61.6 1.7 9.8e-17 61.1 1.0 1.5 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EOO01099.1 - 0.00098 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain SH3_1 PF00018.23 EOO01101.1 - 2.1e-27 94.2 0.0 2.1e-13 49.4 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EOO01101.1 - 4.7e-19 67.7 0.2 1e-08 34.6 0.0 3.4 4 0 0 4 4 4 2 Variant SH3 domain PX PF00787.19 EOO01101.1 - 1e-14 54.2 0.0 2.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EOO01101.1 - 6.2e-13 48.0 0.0 3.4e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EOO01101.1 - 1.2e-09 37.6 0.0 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 EOO01101.1 - 0.0012 18.5 0.1 0.0047 16.5 0.1 2.0 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_11 PF08241.7 EOO01102.1 - 6.5e-20 71.4 0.0 9.6e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO01102.1 - 8.3e-14 52.1 0.0 1.4e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01102.1 - 3.8e-10 40.1 0.0 6.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO01102.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO01102.1 - 1.7e-08 34.7 0.0 2.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01102.1 - 4e-08 32.9 0.0 5.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO01102.1 - 4.4e-07 29.9 0.2 1.1e-06 28.7 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EOO01102.1 - 7.8e-05 21.8 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EOO01102.1 - 8.7e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EOO01102.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EOO01102.1 - 0.0025 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 EOO01102.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.15 EOO01102.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_hydro_cc PF11790.3 EOO01103.1 - 4.7e-58 196.4 0.0 5.3e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Tyrosinase PF00264.15 EOO01105.1 - 1.6e-26 93.8 6.7 2.8e-26 93.0 4.7 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase IBR PF01485.16 EOO01106.1 - 0.0048 16.7 2.8 0.0048 16.7 1.9 4.0 3 1 0 3 3 3 2 IBR domain Sugar_tr PF00083.19 EOO01107.1 - 7.4e-23 80.8 7.0 1.2e-17 63.6 0.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01107.1 - 2.6e-18 65.8 2.9 4.4e-18 65.1 2.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01107.1 - 2.2e-06 26.3 2.3 4.2e-06 25.4 0.2 1.9 1 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EOO01107.1 - 0.002 16.4 0.5 0.0024 16.1 0.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EOO01107.1 - 0.012 14.1 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter Ion_trans PF00520.26 EOO01108.1 - 6.5e-08 32.0 15.4 3.4e-07 29.7 10.6 2.2 1 1 0 1 1 1 1 Ion transport protein DUF3814 PF12769.2 EOO01108.1 - 0.025 14.7 0.3 0.025 14.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) Pyr_redox_3 PF13738.1 EOO01109.1 - 1.5e-26 93.7 0.0 2.4e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO01109.1 - 3.5e-16 58.4 0.2 3.3e-13 48.6 0.1 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EOO01109.1 - 3.4e-10 39.7 0.0 1.1e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EOO01109.1 - 7.9e-07 28.2 1.0 0.00057 18.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EOO01109.1 - 1.9e-06 27.9 0.0 1.6e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO01109.1 - 0.0005 19.8 0.0 0.0073 16.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EOO01109.1 - 0.0013 17.8 0.1 0.0036 16.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EOO01109.1 - 0.0015 17.5 0.0 0.37 9.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EOO01109.1 - 0.022 14.8 0.1 12 6.0 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EOO01109.1 - 0.03 13.2 0.0 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EOO01109.1 - 0.064 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_trans_1_4 PF13692.1 EOO01110.1 - 4e-25 88.5 0.0 1.1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EOO01110.1 - 7.2e-07 28.7 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EOO01110.1 - 4.7e-05 23.5 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Queuosine_synth PF02547.10 EOO01110.1 - 0.091 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein Fungal_trans PF04082.13 EOO01111.1 - 0.0011 17.9 0.1 0.0023 16.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2b PF00587.20 EOO01112.1 - 1.7e-21 76.5 0.0 3.1e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EOO01112.1 - 6.4e-21 74.0 0.3 1.3e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EOO01112.1 - 2.1e-16 59.6 0.0 5.1e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain SGL PF08450.7 EOO01113.1 - 2.6e-26 92.5 0.0 3e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EOO01113.1 - 1.8e-05 24.6 0.0 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 Strictosidine synthase Arylesterase PF01731.15 EOO01113.1 - 0.018 15.0 0.0 3.5 7.6 0.0 2.7 2 1 0 2 2 2 0 Arylesterase CAP PF00188.21 EOO01114.1 - 4.6e-18 65.8 3.3 5.6e-18 65.6 2.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-AN1 PF01428.11 EOO01115.1 - 1.2e-25 89.0 20.1 6e-13 48.4 5.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EOO01115.1 - 0.00024 20.9 16.0 0.0063 16.3 2.8 2.5 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 EOO01115.1 - 0.007 16.5 14.0 0.088 13.0 2.6 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Zn_peptidase_2 PF04298.7 EOO01115.1 - 0.14 11.4 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DRP PF06044.7 EOO01115.1 - 0.6 9.0 5.9 4.4 6.2 0.6 2.4 1 1 0 2 2 2 0 Dam-replacing family HypA PF01155.14 EOO01115.1 - 8 6.1 9.5 0.45 10.2 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Ank_2 PF12796.2 EOO01116.1 - 3.8e-60 200.2 14.8 6.6e-08 32.7 0.0 14.3 8 4 4 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01116.1 - 3.5e-26 89.6 28.0 0.0033 17.1 0.0 20.5 22 1 0 22 22 22 6 Ankyrin repeat Ank_4 PF13637.1 EOO01116.1 - 3.2e-19 68.8 15.2 0.011 16.1 0.0 14.4 14 2 3 17 17 17 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01116.1 - 2.7e-18 64.2 14.3 0.81 10.1 0.0 19.9 26 0 0 26 26 26 2 Ankyrin repeat Ank_5 PF13857.1 EOO01116.1 - 4.4e-16 58.5 9.6 6.3e-05 23.0 0.0 11.8 12 3 3 15 15 15 3 Ankyrin repeats (many copies) BIR PF00653.16 EOO01117.1 - 2.1e-19 69.7 0.1 3.8e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain adh_short PF00106.20 EOO01118.1 - 7.1e-06 26.0 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EOO01118.1 - 0.00053 20.0 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EOO01118.1 - 0.0015 18.9 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EOO01118.1 - 0.0054 16.0 0.2 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 2-Hacid_dh_C PF02826.14 EOO01118.1 - 0.0072 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EOO01118.1 - 0.0097 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EOO01118.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EOO01118.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EOO01118.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EOO01118.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Transp_cyt_pur PF02133.10 EOO01119.1 - 1.1e-26 93.3 32.2 2.6e-26 92.1 22.3 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin EAP30 PF04157.11 EOO01120.1 - 1.2e-58 197.9 0.0 1.5e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EOO01120.1 - 6e-27 93.2 0.0 1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EOO01120.1 - 7e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Pyr_redox_3 PF13738.1 EOO01121.1 - 5.1e-14 52.8 0.0 1.6e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO01121.1 - 8.1e-10 37.5 0.0 1.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EOO01121.1 - 3.7e-07 29.3 0.0 0.00012 21.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EOO01121.1 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EOO01121.1 - 0.0023 17.8 0.0 0.0084 16.0 0.0 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO01121.1 - 0.028 14.7 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase QCR10 PF09796.4 EOO01122.1 - 3.2e-22 77.9 0.2 4e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EOO01122.1 - 0.025 14.2 0.1 0.058 13.1 0.1 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein SET PF00856.23 EOO01123.1 - 1.3e-17 64.6 0.8 9.8e-17 61.7 0.0 2.8 3 1 0 3 3 3 1 SET domain TPR_11 PF13414.1 EOO01123.1 - 6.8e-12 44.8 5.4 3.5e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EOO01123.1 - 2.4e-08 33.2 1.4 0.0025 17.5 0.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EOO01123.1 - 0.00025 20.9 3.3 0.00073 19.4 0.9 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO01123.1 - 0.00033 20.1 2.4 0.062 12.9 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EOO01123.1 - 0.0033 17.9 0.6 0.058 14.0 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EOO01123.1 - 0.035 14.5 1.0 0.38 11.3 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EOO01123.1 - 0.038 14.6 4.0 0.08 13.6 1.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EOO01123.1 - 0.039 13.7 2.8 0.13 12.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EOO01123.1 - 0.13 12.6 8.5 0.28 11.5 0.8 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat SNO PF01174.14 EOO01124.1 - 6.3e-54 182.4 0.0 2.1e-43 148.1 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EOO01124.1 - 5.2e-09 35.8 0.0 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EOO01124.1 - 0.0043 16.5 0.0 0.036 13.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EOO01124.1 - 0.0058 16.1 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EOO01124.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase CoA_binding_2 PF13380.1 EOO01125.1 - 3e-28 98.3 0.1 4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain adh_short PF00106.20 EOO01126.1 - 1.3e-18 67.4 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01126.1 - 2.2e-14 53.8 0.0 3.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EOO01126.1 - 0.046 12.8 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.7 EOO01127.1 - 4.9e-07 29.4 0.0 1.9e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO01127.1 - 2.1e-05 24.0 0.1 3.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAM176 PF14851.1 EOO01128.1 - 0.019 14.6 2.3 0.026 14.2 1.6 1.2 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.1 EOO01128.1 - 0.038 13.2 3.9 0.047 12.9 2.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Radial_spoke PF04712.7 EOO01128.1 - 0.059 12.1 1.5 0.063 12.0 1.1 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein BUD22 PF09073.5 EOO01128.1 - 0.31 10.0 5.2 0.32 10.0 3.6 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 EOO01128.1 - 0.55 9.1 8.3 0.66 8.9 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Med17 PF10156.4 EOO01128.1 - 0.75 7.9 6.3 0.95 7.6 4.4 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RRN3 PF05327.6 EOO01128.1 - 0.84 7.6 6.0 0.96 7.4 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 EOO01128.1 - 2.2 7.8 13.7 2.9 7.4 9.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 EOO01128.1 - 2.8 7.1 11.3 3.5 6.8 7.8 1.0 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EOO01128.1 - 3.4 6.0 12.9 4 5.7 8.9 1.0 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 EOO01128.1 - 5.6 5.0 5.4 6.8 4.8 3.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Mak16 PF04874.9 EOO01128.1 - 9.6 6.3 21.8 16 5.6 15.1 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region DUF1996 PF09362.5 EOO01129.1 - 1.1e-58 198.6 0.8 1.4e-58 198.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.20 EOO01130.1 - 8.6e-34 116.8 0.0 9.8e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01130.1 - 4.6e-16 58.6 0.0 5.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO01130.1 - 0.0029 16.6 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Transketolase_N PF00456.16 EOO01131.1 - 1.3e-103 346.3 0.0 1.7e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EOO01131.1 - 4.3e-34 117.5 0.0 1.2e-33 116.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EOO01131.1 - 7.1e-08 31.7 0.0 7.2e-06 25.1 0.0 3.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EOO01131.1 - 6.7e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EOO01131.1 - 0.00044 19.8 2.4 0.00067 19.2 0.2 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EOO01131.1 - 0.0067 15.9 0.0 2.7 7.4 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.15 EOO01131.1 - 0.0089 14.7 0.1 0.017 13.8 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Scm3 PF10384.4 EOO01131.1 - 0.03 13.8 0.4 0.064 12.7 0.3 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 GSDH PF07995.6 EOO01133.1 - 6.1e-118 393.6 0.1 7.2e-118 393.4 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EOO01133.1 - 0.00022 21.0 0.0 0.14 12.1 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.6 EOO01133.1 - 0.0026 17.5 2.8 3.7 7.8 0.0 4.1 4 0 0 4 4 4 2 Two component regulator propeller MIP PF00230.15 EOO01134.1 - 3.4e-47 160.8 13.6 4.4e-47 160.4 9.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Epimerase PF01370.16 EOO01135.1 - 9.5e-42 143.0 0.0 1.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EOO01135.1 - 2.5e-23 81.7 0.1 5e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EOO01135.1 - 8.3e-13 47.6 0.0 3.9e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EOO01135.1 - 5e-11 42.0 0.0 7.3e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EOO01135.1 - 1.2e-09 37.5 0.0 8.4e-08 31.4 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EOO01135.1 - 2.5e-06 27.5 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EOO01135.1 - 5.5e-06 25.4 0.0 1.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EOO01135.1 - 9.6e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EOO01135.1 - 0.00015 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 EOO01135.1 - 0.0068 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 EOO01135.1 - 0.016 15.7 0.0 3.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 EOO01135.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNF2_N PF00176.18 EOO01137.1 - 6.3e-37 126.9 0.1 1.7e-32 112.3 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EOO01137.1 - 2.1e-05 24.1 11.9 4.3e-05 23.0 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EOO01137.1 - 2.9e-05 23.8 0.0 8.4e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EOO01137.1 - 8.2e-05 22.5 11.2 0.00016 21.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EOO01137.1 - 0.00025 20.8 10.7 0.00066 19.4 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EOO01137.1 - 0.0035 17.1 11.6 0.0072 16.1 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain AAA_34 PF13872.1 EOO01137.1 - 0.0089 14.8 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.1 EOO01137.1 - 0.027 14.1 11.6 0.052 13.2 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO01137.1 - 0.043 13.5 12.4 0.11 12.2 8.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DHO_dh PF01180.16 EOO01138.1 - 1.2e-64 218.1 0.0 1.5e-62 211.2 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EOO01138.1 - 2.6e-05 23.5 0.8 0.065 12.4 0.1 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EOO01138.1 - 0.00037 19.4 0.7 0.0021 16.9 0.2 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase OCD_Mu_crystall PF02423.10 EOO01139.1 - 2.8e-13 49.3 0.0 3.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EOO01139.1 - 4.5e-07 30.0 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TruB_C PF09142.6 EOO01139.1 - 0.0073 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal GFO_IDH_MocA PF01408.17 EOO01139.1 - 0.14 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold EMP70 PF02990.11 EOO01140.1 - 1.4e-198 660.5 2.3 1.7e-198 660.2 1.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 EOO01140.1 - 4.6 6.4 6.2 0.51 9.5 1.3 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family NUC153 PF08159.7 EOO01141.1 - 2.8e-14 52.3 0.4 2.8e-14 52.3 0.3 3.4 3 1 0 3 3 3 2 NUC153 domain Aldedh PF00171.17 EOO01142.1 - 6.4e-79 265.4 1.1 4.2e-41 140.7 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 EOO01142.1 - 0.0051 15.5 0.1 0.0091 14.7 0.1 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EOO01142.1 - 0.032 13.4 0.2 0.68 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) DUF2781 PF10914.3 EOO01143.1 - 5.7e-25 87.8 5.6 6.4e-25 87.6 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) adh_short PF00106.20 EOO01144.1 - 6.4e-22 78.2 0.6 1.1e-21 77.4 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01144.1 - 1.8e-08 34.4 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO01144.1 - 2.6e-07 30.4 0.1 6.4e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EOO01144.1 - 8.9e-06 25.0 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EOO01144.1 - 2.3e-05 23.9 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO01144.1 - 4.8e-05 23.4 2.6 9.5e-05 22.4 1.8 1.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EOO01144.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EOO01144.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PLDc_2 PF13091.1 EOO01145.1 - 3.4e-19 68.8 0.0 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 EOO01145.1 - 0.00054 19.0 0.0 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB PLDc PF00614.17 EOO01145.1 - 0.0016 18.2 1.8 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Cellulase PF00150.13 EOO01146.1 - 2.2e-23 82.8 0.3 2.9e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EOO01146.1 - 5.1e-06 25.6 0.0 8.8e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EOO01146.1 - 5.1e-05 23.6 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EOO01146.1 - 0.0019 17.3 0.5 0.0068 15.5 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Alpha-amylase PF00128.19 EOO01146.1 - 0.048 13.0 0.5 6.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Glyco_hydro_10 PF00331.15 EOO01146.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 IP_trans PF02121.13 EOO01146.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Peptidase_S8 PF00082.17 EOO01147.1 - 3.8e-60 203.4 0.1 5.4e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EOO01147.1 - 1.2e-10 41.7 0.2 2.1e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) FixG_C PF11614.3 EOO01147.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Mmp37 PF09139.6 EOO01148.1 - 1.4e-132 441.7 0.0 1.6e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Sugar_tr PF00083.19 EOO01149.1 - 2.8e-80 270.1 22.7 9.3e-66 222.2 4.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01149.1 - 2.4e-19 69.2 24.7 3.1e-19 68.9 16.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO01149.1 - 7.9e-05 21.0 1.0 0.00015 20.0 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 EOO01149.1 - 0.0049 16.9 0.4 0.019 15.0 0.3 2.0 1 0 0 1 1 1 1 Phage holin family 2 ADH_zinc_N PF00107.21 EOO01151.1 - 2.1e-26 92.0 0.1 6.2e-26 90.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO01151.1 - 1.2e-16 61.7 0.0 3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO01151.1 - 1.8e-11 43.7 0.0 4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Caps_synth PF05704.7 EOO01151.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Methyltransf_19 PF04672.7 EOO01151.1 - 0.17 11.1 0.7 5.5 6.1 0.2 2.3 2 0 0 2 2 2 0 S-adenosyl methyltransferase muHD PF10291.4 EOO01152.1 - 2.6e-68 230.0 0.0 3.7e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EOO01152.1 - 2.6e-10 40.3 0.0 9.7e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain UPF0227 PF05728.7 EOO01152.1 - 0.0081 15.8 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Mpv17_PMP22 PF04117.7 EOO01153.1 - 1e-17 63.4 0.7 1e-17 63.4 0.5 2.0 2 1 0 2 2 2 1 Mpv17 / PMP22 family TspO_MBR PF03073.10 EOO01153.1 - 0.38 10.2 4.3 4 6.9 3.5 2.1 1 1 1 2 2 2 0 TspO/MBR family DIE2_ALG10 PF04922.7 EOO01154.1 - 2.3e-07 30.2 9.8 1.7e-06 27.3 0.1 2.4 3 0 0 3 3 3 2 DIE2/ALG10 family TRAM1 PF08390.6 EOO01154.1 - 0.29 10.6 1.4 0.77 9.3 1.0 1.7 1 0 0 1 1 1 0 TRAM1-like protein F-box-like PF12937.2 EOO01156.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like TFIIIC_delta PF12657.2 EOO01157.1 - 4.2e-18 65.6 1.2 1.1e-15 57.8 0.2 3.4 2 1 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EOO01157.1 - 4e-11 42.6 3.5 8.2e-11 41.6 2.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ACOX PF01756.14 EOO01158.1 - 1.6e-38 132.0 0.0 1e-37 129.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EOO01158.1 - 8.7e-30 103.5 0.4 2.3e-29 102.2 0.2 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EOO01158.1 - 7.4e-11 41.3 1.1 1.5e-10 40.4 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EOO01158.1 - 8.1e-06 26.0 0.4 0.0008 19.5 0.3 2.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EOO01158.1 - 0.032 14.7 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain GATase_2 PF00310.16 EOO01159.1 - 1.4e-19 70.0 0.0 2.1e-14 53.0 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EOO01159.1 - 9.3e-17 61.2 0.0 1.5e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EOO01159.1 - 1.3e-14 54.0 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EOO01159.1 - 4.3e-06 25.6 0.0 6.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3246 PF11596.3 EOO01160.1 - 8.6 5.5 16.4 14 4.8 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Carb_anhydrase PF00194.16 EOO01161.1 - 9.8e-05 21.4 1.9 0.0059 15.6 0.6 2.5 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Inhibitor_I36 PF03995.8 EOO01162.1 - 0.0028 18.0 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor family I36 DUF4419 PF14388.1 EOO01163.1 - 1.9e-60 204.6 0.0 2.3e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PTR2 PF00854.16 EOO01165.1 - 1.2e-18 67.1 4.2 1.2e-18 67.1 2.9 2.3 1 1 0 2 2 2 1 POT family Cation_efflux PF01545.16 EOO01165.1 - 0.017 14.2 0.2 0.031 13.3 0.2 1.5 1 0 0 1 1 1 0 Cation efflux family Dynamin_N PF00350.18 EOO01166.1 - 3.6e-05 23.6 0.4 0.00042 20.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Aldo_ket_red PF00248.16 EOO01167.1 - 1.1e-18 67.0 0.0 1.3e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ALF PF03752.8 EOO01168.1 - 0.027 14.3 0.3 0.06 13.2 0.2 1.5 1 0 0 1 1 1 0 Short repeats of unknown function FAD_binding_4 PF01565.18 EOO01169.1 - 1.2e-19 70.1 1.0 2.5e-19 69.1 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EOO01169.1 - 3.7e-12 45.9 0.1 1.8e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like PAPS_reduct PF01507.14 EOO01170.1 - 8.8e-28 97.2 0.0 5.6e-25 88.1 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Mito_carr PF00153.22 EOO01171.1 - 4.4e-58 192.9 6.9 3.3e-20 71.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 EOO01172.1 - 6.6e-11 41.9 0.0 1.9e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO01172.1 - 7.1e-10 38.5 0.0 8e-09 35.1 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EOO01172.1 - 0.0019 18.2 0.1 0.0039 17.2 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Peptidase_M24 PF00557.19 EOO01172.1 - 0.078 12.5 0.0 1 8.9 0.0 2.5 2 1 2 4 4 4 0 Metallopeptidase family M24 Glyco_hydro_16 PF00722.16 EOO01173.1 - 1e-12 47.7 0.7 1.8e-12 46.9 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UQ_con PF00179.21 EOO01174.1 - 3.8e-37 126.8 0.0 4.6e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO01174.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Amidohydro_2 PF04909.9 EOO01175.1 - 1.1e-22 80.9 0.1 1.2e-22 80.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase DEAD PF00270.24 EOO01176.1 - 9.9e-44 148.7 0.0 2.3e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EOO01176.1 - 7.8e-26 89.4 0.0 2.1e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EOO01176.1 - 1e-19 70.1 0.1 4.8e-19 68.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EOO01176.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain YodL PF14191.1 EOO01177.1 - 0.091 13.2 0.0 13 6.3 0.0 2.4 2 0 0 2 2 2 0 YodL-like adh_short PF00106.20 EOO01178.1 - 7.5e-08 32.4 0.0 9.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01178.1 - 0.00043 19.9 0.1 0.00055 19.6 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO01178.1 - 0.029 14.1 0.5 0.058 13.1 0.3 1.5 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase UBN2 PF14223.1 EOO01178.1 - 0.047 13.4 0.4 0.57 9.9 0.3 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type ADH_zinc_N PF00107.21 EOO01178.1 - 0.054 13.0 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase H-kinase_dim PF02895.9 EOO01178.1 - 0.059 13.7 0.3 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Bac_luciferase PF00296.15 EOO01180.1 - 3.4e-66 223.4 0.2 4.7e-66 222.9 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S8 PF00082.17 EOO01181.1 - 1.2e-31 109.9 0.5 6.1e-16 58.4 0.0 2.3 1 1 1 2 2 2 2 Subtilase family DUF1034 PF06280.7 EOO01181.1 - 1.1e-11 45.0 0.0 2.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) SGL PF08450.7 EOO01183.1 - 5.4e-20 71.8 0.0 9.7e-20 70.9 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EOO01183.1 - 1.3e-05 24.8 0.7 0.074 13.0 0.1 3.0 2 0 0 2 2 2 2 NHL repeat Str_synth PF03088.11 EOO01183.1 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EOO01183.1 - 0.013 15.4 0.0 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 Arylesterase adh_short PF00106.20 EOO01184.1 - 6.1e-19 68.5 0.0 7.1e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01184.1 - 5.9e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO01184.1 - 0.00072 19.0 0.0 0.00087 18.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EOO01184.1 - 0.0079 15.9 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EOO01184.1 - 0.013 14.1 0.0 0.028 13.1 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DJ-1_PfpI PF01965.19 EOO01186.1 - 1.5e-27 95.8 0.7 4.7e-27 94.2 0.5 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EOO01186.1 - 1.6e-17 62.7 0.0 3.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 EOO01186.1 - 0.0043 16.6 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EOO01186.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative amidotransferase HIF-1a_CTAD PF08778.5 EOO01186.1 - 0.069 12.6 0.1 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain Sad1_UNC PF07738.8 EOO01187.1 - 3.1e-06 27.0 0.0 8.5e-05 22.3 0.0 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Methyltransf_31 PF13847.1 EOO01188.1 - 3.2e-26 91.7 0.0 4.4e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO01188.1 - 4.6e-23 81.5 0.0 9.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO01188.1 - 9.3e-17 60.9 0.0 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EOO01188.1 - 3.8e-14 53.2 0.0 1.1e-13 51.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01188.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO01188.1 - 5e-12 46.0 0.0 1.6e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO01188.1 - 1.1e-10 41.5 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO01188.1 - 3.7e-09 36.1 0.0 5.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EOO01188.1 - 7.5e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO01188.1 - 2.3e-06 26.7 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EOO01188.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EOO01188.1 - 4.2e-05 22.9 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EOO01188.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 EOO01188.1 - 0.0009 17.6 0.0 0.0013 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.7 EOO01188.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 EOO01188.1 - 0.0022 17.1 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EOO01188.1 - 0.0023 16.6 0.0 0.0032 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EOO01188.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EOO01188.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EOO01188.1 - 0.033 13.2 0.0 0.055 12.5 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase CheR PF01739.13 EOO01188.1 - 0.13 11.5 0.0 4 6.6 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Cpn60_TCP1 PF00118.19 EOO01189.1 - 4.3e-144 480.7 12.7 4.9e-144 480.5 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SUR7 PF06687.7 EOO01190.1 - 4.3e-19 68.9 0.1 4.7e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EOO01190.1 - 6.8e-06 26.0 1.0 1.1e-05 25.3 0.7 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 TMEM125 PF15109.1 EOO01190.1 - 0.12 12.4 1.0 0.23 11.5 0.7 1.5 1 0 0 1 1 1 0 TMEM125 protein family Amastin PF07344.6 EOO01190.1 - 0.38 10.3 3.1 0.64 9.6 2.1 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_2 PF13903.1 EOO01190.1 - 0.49 10.0 7.9 1.2 8.8 5.5 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NMT1 PF09084.6 EOO01191.1 - 4.3e-08 33.0 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 EOO01191.1 - 0.00034 20.0 0.1 0.00052 19.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 EOO01191.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family OpuAC PF04069.7 EOO01191.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system MAD PF05557.8 EOO01192.1 - 2.8e-53 181.1 68.0 3.8e-53 180.6 47.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein CCDC155 PF14662.1 EOO01192.1 - 0.0037 16.8 9.1 0.0037 16.8 6.3 4.7 2 1 1 4 4 4 2 Coiled-coil region of CCDC155 HALZ PF02183.13 EOO01192.1 - 2.5 7.9 0.0 2.5 7.9 0.0 8.9 10 0 0 10 10 10 0 Homeobox associated leucine zipper Sugar_tr PF00083.19 EOO01193.1 - 4.2e-109 365.1 26.3 4.8e-109 364.9 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01193.1 - 5.9e-22 77.8 35.1 3.2e-14 52.4 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO01193.1 - 1.8e-08 33.0 8.8 2.3e-05 22.8 3.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) zf-LITAF-like PF10601.4 EOO01193.1 - 3.3 7.6 9.7 2.5 8.0 0.0 4.3 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Lipase_GDSL_2 PF13472.1 EOO01194.1 - 4.9e-18 65.8 0.0 6.8e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO01194.1 - 9.9e-17 61.5 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EOO01194.1 - 8.5e-06 25.6 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNF2_N PF00176.18 EOO01195.1 - 6.6e-71 238.5 0.9 2.3e-70 236.7 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EOO01195.1 - 1.6e-16 59.8 0.0 5.9e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 EOO01196.1 - 2.9e-11 42.6 33.1 2.9e-11 42.6 23.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EOO01196.1 - 4.5e-10 39.2 5.7 4.5e-10 39.2 3.9 3.6 3 2 1 4 4 4 1 Ion channel regulatory protein UNC-93 Aldedh PF00171.17 EOO01197.1 - 2.1e-124 415.3 2.4 2.8e-124 414.9 1.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Iso_dh PF00180.15 EOO01197.1 - 2.1e-87 293.2 0.0 3e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAC3_GANP PF03399.11 EOO01198.1 - 1.4e-66 223.9 0.8 1.9e-66 223.5 0.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Rieske PF00355.21 EOO01199.1 - 1.9e-17 62.6 0.1 3.9e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EOO01199.1 - 3.3e-17 62.4 0.5 5.7e-17 61.7 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Peptidase_M28 PF04389.12 EOO01200.1 - 3.3e-26 92.1 0.0 5.7e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EOO01200.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_Tnp_Tc5 PF03221.11 EOO01201.1 - 2e-16 59.5 2.7 6.8e-16 57.8 0.2 2.6 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain SOR_SNZ PF01680.12 EOO01203.1 - 6.7e-108 359.0 7.0 9.1e-108 358.6 4.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EOO01203.1 - 5.6e-09 35.4 4.6 1.3e-06 27.6 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EOO01203.1 - 0.00015 20.9 0.4 0.0015 17.6 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EOO01203.1 - 0.00025 20.3 0.3 0.092 12.0 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EOO01203.1 - 0.00051 18.9 0.1 0.34 9.7 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EOO01203.1 - 0.0032 16.4 0.5 0.071 12.0 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 EOO01203.1 - 0.019 14.3 0.4 0.45 9.8 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 EOO01203.1 - 0.037 13.1 0.3 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 EOO01203.1 - 0.12 11.4 9.2 0.1 11.7 0.7 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase zf-C2H2_jaz PF12171.3 EOO01204.1 - 5e-07 29.6 0.1 1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EOO01204.1 - 2.8e-05 24.1 0.3 5.1e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EOO01204.1 - 8e-05 22.4 12.6 8e-05 22.4 8.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 EOO01204.1 - 0.011 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger Rotamase_2 PF13145.1 EOO01204.1 - 0.12 12.9 11.9 2.3 8.8 0.1 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain Hus1 PF04005.7 EOO01204.1 - 0.46 9.3 3.2 0.7 8.7 2.2 1.2 1 0 0 1 1 1 0 Hus1-like protein Atg14 PF10186.4 EOO01204.1 - 5.8 5.7 9.7 0.52 9.1 3.8 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Vfa1 PF08432.5 EOO01204.1 - 6.4 6.7 14.0 1.2 9.1 5.0 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cation_efflux PF01545.16 EOO01205.1 - 3.6e-61 206.7 0.9 4.8e-61 206.3 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EOO01205.1 - 1.6e-05 24.0 17.0 1.6e-05 24.0 11.8 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter 4HBT PF03061.17 EOO01206.1 - 3e-06 27.2 0.1 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Sas10_Utp3 PF04000.10 EOO01207.1 - 5.7e-16 58.4 2.8 5.7e-16 58.4 1.9 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DNA_pol_phi PF04931.8 EOO01207.1 - 0.16 9.6 5.1 0.26 9.0 3.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4407 PF14362.1 EOO01207.1 - 0.84 8.5 9.5 0.16 10.8 4.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.16 EOO01208.1 - 6.8e-65 218.7 0.1 7.6e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tom5 PF10642.4 EOO01208.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase SKG6 PF08693.5 EOO01209.1 - 0.00023 20.3 2.0 0.00051 19.2 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EOO01209.1 - 0.0015 17.9 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF347 PF03988.7 EOO01209.1 - 0.035 13.9 0.7 0.068 13.0 0.5 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Yip1 PF04893.12 EOO01209.1 - 0.042 13.3 0.1 0.088 12.3 0.1 1.5 2 0 0 2 2 2 0 Yip1 domain Rax2 PF12768.2 EOO01209.1 - 0.064 12.4 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EOO01209.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EOO01209.1 - 0.31 10.7 0.9 0.54 9.9 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain FAD_binding_4 PF01565.18 EOO01210.1 - 9e-26 90.0 0.9 1.7e-25 89.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EOO01210.1 - 9.5e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EOO01210.1 - 0.00056 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding RAP1 PF07218.6 EOO01211.1 - 8.3 4.3 10.1 8.8 4.2 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AFG1_ATPase PF03969.11 EOO01212.1 - 4.5e-97 325.1 0.0 3.1e-92 309.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EOO01212.1 - 1e-05 25.6 0.4 0.021 14.7 0.0 2.8 2 1 0 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.13 EOO01212.1 - 0.00017 21.2 0.6 0.4 10.2 0.1 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA PF00004.24 EOO01212.1 - 0.0032 17.6 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EOO01212.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EOO01212.1 - 0.0084 16.2 0.7 0.053 13.6 0.0 2.6 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.22 EOO01212.1 - 0.022 15.0 0.0 11 6.3 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Cep57_MT_bd PF06657.8 EOO01212.1 - 0.037 13.9 1.7 1.1 9.2 0.4 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RNA_helicase PF00910.17 EOO01212.1 - 0.04 14.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EOO01212.1 - 0.043 13.4 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 EOO01212.1 - 0.048 13.7 0.0 0.71 9.9 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain UvrD-helicase PF00580.16 EOO01212.1 - 0.069 12.4 0.0 0.14 11.3 0.0 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GlutR_dimer PF00745.15 EOO01212.1 - 0.15 11.9 0.6 0.51 10.3 0.2 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Pyridox_oxidase PF01243.15 EOO01213.1 - 4.7e-10 39.3 0.0 1e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 EOO01213.1 - 0.056 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain p450 PF00067.17 EOO01214.1 - 4.4e-36 124.3 0.0 8e-36 123.5 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 NDT80_PhoG PF05224.7 EOO01215.1 - 8.1e-47 159.6 0.0 1.4e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Peptidase_M3 PF01432.15 EOO01216.1 - 9.3e-159 529.3 0.0 1.1e-158 529.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EOO01216.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Effector protein Acyl-CoA_dh_N PF02771.11 EOO01217.1 - 1.3e-16 61.1 0.1 3.8e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EOO01217.1 - 3.5e-15 56.3 0.7 5.7e-15 55.7 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EOO01217.1 - 5.8e-08 32.1 0.7 1.3e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EOO01217.1 - 0.041 14.1 0.5 0.071 13.3 0.4 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain tRNA_bind PF01588.15 EOO01218.1 - 1.2e-23 82.7 0.3 3.1e-22 78.2 0.2 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EOO01218.1 - 4.9e-08 33.3 0.1 1.6e-07 31.7 0.0 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EOO01218.1 - 0.0011 18.9 0.1 0.0045 16.9 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EOO01218.1 - 0.0026 17.5 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SMC_hinge PF06470.8 EOO01218.1 - 0.0059 16.5 1.6 0.013 15.4 1.1 1.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Glyco_hydro_72 PF03198.9 EOO01219.1 - 2.1e-66 224.0 0.7 2.5e-66 223.8 0.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EOO01219.1 - 1.2e-05 24.6 0.1 0.0003 20.0 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Swi5 PF07061.6 EOO01220.1 - 2e-21 75.5 0.3 3.9e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Swi5 GvpK PF05121.7 EOO01220.1 - 0.0086 15.8 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Gas vesicle protein K RIC1 PF07064.8 EOO01220.1 - 0.12 11.8 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RIC1 ComA PF02679.10 EOO01221.1 - 2.1e-72 243.1 0.0 2.4e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Smr PF01713.16 EOO01221.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Smr domain FliX PF10768.4 EOO01222.1 - 0.017 15.3 0.5 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 Class II flagellar assembly regulator Glyco_transf_28 PF03033.15 EOO01223.1 - 3e-18 65.9 0.0 3.2e-17 62.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EOO01223.1 - 9.1e-05 21.1 0.0 0.00016 20.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 EOO01223.1 - 0.002 17.5 9.4 0.29 10.8 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Meth_synt_2 PF01717.13 EOO01224.1 - 2.8e-18 65.9 0.0 3.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EOO01224.1 - 9.4e-05 21.8 0.0 0.035 13.3 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 EOO01225.1 - 2.9e-12 46.1 1.2 2.9e-12 46.1 0.8 2.4 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EOO01225.1 - 3.8e-11 41.8 11.2 10 6.5 0.1 10.9 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.2 EOO01225.1 - 3.4e-09 36.1 7.7 0.3 10.7 0.0 7.5 6 2 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EOO01225.1 - 9.9e-08 31.6 12.4 0.19 11.4 0.1 5.6 4 1 1 5 5 5 4 Leucine rich repeat F-box PF00646.28 EOO01225.1 - 8.8e-06 25.2 0.1 4.9e-05 22.8 0.0 2.4 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EOO01225.1 - 0.00013 21.5 19.4 10 6.5 0.0 9.8 8 3 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 EOO01225.1 - 0.24 11.7 21.2 10 6.8 0.0 8.5 9 1 1 10 10 10 0 Leucine rich repeat DCP1 PF06058.8 EOO01226.1 - 2e-15 56.9 0.0 3.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EOO01227.1 - 7.4e-20 71.9 0.4 1.5e-18 67.6 0.2 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Hydantoinase_B PF02538.9 EOO01228.1 - 3e-188 626.3 0.0 3.8e-188 626.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO01228.1 - 7.4e-98 327.2 0.2 2.4e-97 325.5 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO01228.1 - 8.5e-55 184.9 1.8 9.3e-54 181.5 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MARVEL PF01284.18 EOO01229.1 - 3.4e-07 30.1 15.7 4.9e-07 29.6 10.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EOO01229.1 - 0.15 11.6 20.8 0.067 12.8 10.2 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling Oxidored_q2 PF00420.19 EOO01229.1 - 0.8 9.3 12.3 2.4 7.7 6.2 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1479 PF07350.7 EOO01230.1 - 1.4e-21 76.5 0.0 1.6e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_90 PF05686.7 EOO01231.1 - 1.1e-12 47.3 4.0 4.5e-11 42.0 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 Ank_2 PF12796.2 EOO01232.1 - 4.3e-22 78.2 0.0 1.5e-10 41.2 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01232.1 - 1.7e-18 65.4 7.7 0.0041 16.8 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EOO01232.1 - 1.3e-13 51.0 1.4 0.00016 22.0 0.1 6.0 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01232.1 - 2.3e-10 39.6 7.7 0.97 9.8 0.0 7.7 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 EOO01232.1 - 2.8e-07 30.5 1.0 0.45 10.8 0.0 5.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) CorA PF01544.13 EOO01233.1 - 0.0023 17.0 0.0 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Lactamase_B PF00753.22 EOO01235.1 - 6.9e-07 29.1 0.1 9.7e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EOO01235.1 - 0.00053 19.5 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_3 PF00933.16 EOO01236.1 - 2.9e-65 220.1 0.0 4e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO01236.1 - 7e-63 212.1 0.0 3.5e-62 209.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO01236.1 - 1.2e-17 63.5 0.2 3.2e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Phage_tail_X PF05489.7 EOO01236.1 - 0.043 13.2 0.2 0.13 11.8 0.2 1.8 1 0 0 1 1 1 0 Phage Tail Protein X Peptidase_S8 PF00082.17 EOO01237.1 - 1.6e-38 132.4 0.0 3.6e-38 131.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EOO01237.1 - 6.8e-06 26.4 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EOO01237.1 - 0.0017 18.0 0.0 0.0055 16.3 0.0 1.9 1 0 0 1 1 1 1 PA domain Methyltransf_25 PF13649.1 EOO01238.1 - 1.6e-05 25.1 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO01238.1 - 0.00082 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pectinesterase PF01095.14 EOO01239.1 - 1.5e-74 250.3 26.6 4.4e-37 127.2 2.0 4.7 4 1 1 5 5 5 5 Pectinesterase MFS_1 PF07690.11 EOO01240.1 - 5.7e-31 107.5 23.4 5.7e-31 107.5 16.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily HeLo PF14479.1 EOO01241.1 - 2e-40 138.8 0.0 4.3e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_11 PF13414.1 EOO01241.1 - 6.2e-21 73.8 7.8 4e-16 58.4 1.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EOO01241.1 - 3.5e-12 45.3 9.3 4.3e-06 26.1 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EOO01241.1 - 1.3e-10 40.3 9.3 0.00019 21.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EOO01241.1 - 2.3e-07 31.3 5.8 0.00089 19.8 0.6 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EOO01241.1 - 5.2e-05 22.7 0.3 0.071 12.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EOO01241.1 - 6.3e-05 22.8 3.5 0.027 14.3 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EOO01241.1 - 0.0001 22.5 0.8 0.35 11.6 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EOO01241.1 - 0.00049 20.0 0.5 3 8.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EOO01241.1 - 0.00078 19.0 7.2 0.32 10.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EOO01241.1 - 0.016 15.5 4.6 0.54 10.8 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EOO01241.1 - 0.023 15.0 5.9 1.4 9.3 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EOO01241.1 - 3.1 7.7 7.8 0.61 10.0 0.8 2.8 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_S26e PF01283.14 EOO01242.1 - 1.3e-49 167.1 8.9 1.5e-49 167.0 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EOO01242.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_7 PF12838.2 EOO01242.1 - 0.049 14.0 0.6 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EOO01242.1 - 0.056 13.7 0.3 7.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF2278 PF10042.4 EOO01243.1 - 8.8e-59 198.6 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 EOO01243.1 - 3.6e-07 30.2 0.2 2.3e-06 27.6 0.0 2.3 2 1 0 2 2 2 1 Lamin Tail Domain Cys_Met_Meta_PP PF01053.15 EOO01244.1 - 1.3e-141 471.4 0.0 1.5e-141 471.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EOO01244.1 - 1.9e-10 40.3 0.1 9.2e-10 38.0 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EOO01244.1 - 6.5e-08 31.7 0.1 1.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EOO01244.1 - 7.4e-08 31.7 0.1 1.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EOO01244.1 - 0.00014 21.1 0.1 0.0004 19.6 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EOO01244.1 - 0.0017 17.0 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EOO01244.1 - 0.0031 15.8 0.0 0.0041 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EOO01244.1 - 0.0051 15.3 0.1 0.0077 14.7 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) ADH_zinc_N PF00107.21 EOO01244.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IMPDH PF00478.20 EOO01244.1 - 0.091 11.6 0.3 0.16 10.8 0.2 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Abhydrolase_6 PF12697.2 EOO01245.1 - 1.9e-14 54.0 0.0 2.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO01245.1 - 2.1e-08 34.0 0.4 4.1e-08 33.0 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EOO01245.1 - 0.046 12.9 0.0 0.83 8.8 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family Pox_I6 PF04595.8 EOO01245.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family MFS_1 PF07690.11 EOO01246.1 - 4.9e-16 58.3 40.2 9.1e-14 50.9 25.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3290 PF11694.3 EOO01246.1 - 0.057 13.1 3.6 0.044 13.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) TroA PF01297.12 EOO01246.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family FixQ PF05545.6 EOO01246.1 - 6.3 6.5 7.8 3.6 7.3 0.1 3.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ UDPGT PF00201.13 EOO01247.1 - 1e-06 27.6 0.0 6.9e-06 24.8 0.0 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase MFS_1 PF07690.11 EOO01248.1 - 3.6e-36 124.6 31.3 3.6e-36 124.6 21.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EOO01248.1 - 0.011 16.1 0.8 0.071 13.5 0.2 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) YcxB PF14317.1 EOO01248.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein Neurensin PF14927.1 EOO01248.1 - 0.097 12.0 0.3 19 4.5 0.1 3.1 3 0 0 3 3 3 0 Neurensin CoA_trans PF01144.18 EOO01249.1 - 5.2e-100 333.0 0.5 3.1e-58 196.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EOO01249.1 - 0.00028 20.5 0.2 0.00061 19.4 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain ATP-synt PF00231.14 EOO01249.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase Aldo_ket_red PF00248.16 EOO01251.1 - 1.7e-72 243.6 0.0 1.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arginase PF00491.16 EOO01252.1 - 6.9e-76 255.1 0.2 8.3e-76 254.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family Aldo_ket_red PF00248.16 EOO01253.1 - 1.7e-10 40.2 0.0 2.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EOO01254.1 - 1.6e-05 24.6 9.5 1.6e-05 24.6 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EOO01255.1 - 5.4e-98 321.5 1.5 8.1e-19 67.7 0.0 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01255.1 - 9.3e-66 214.5 7.3 1.3e-05 24.7 0.1 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EOO01255.1 - 4.4e-51 170.4 0.9 1.5e-07 31.7 0.0 10.2 4 1 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01255.1 - 1.3e-49 161.1 0.0 0.0014 18.6 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EOO01255.1 - 3.9e-41 138.1 1.8 3.5e-07 30.2 0.0 8.7 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EOO01255.1 - 0.0029 17.1 0.1 3.6 6.9 0.0 4.0 4 1 1 5 5 5 1 Shigella flexneri OspC protein OpuAC PF04069.7 EOO01255.1 - 0.029 13.7 0.0 4.7 6.4 0.0 3.0 1 1 2 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system DUF1110 PF06533.7 EOO01255.1 - 0.097 12.4 1.5 1.6 8.4 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1110) Lyase_1 PF00206.15 EOO01256.1 - 3.4e-20 72.4 0.0 5.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EOO01256.1 - 2.4e-12 46.6 0.0 6.7e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus MFS_1 PF07690.11 EOO01257.1 - 7.6e-34 116.9 27.6 7.6e-34 116.9 19.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EOO01257.1 - 3.6e-05 23.3 2.1 9.8e-05 21.8 1.4 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Gly-zipper_OmpA PF13436.1 EOO01257.1 - 3 7.5 17.6 0.041 13.5 5.6 2.5 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain TraT PF05818.7 EOO01257.1 - 5.7 6.2 6.6 0.66 9.3 0.4 2.2 1 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein Glyco_hydro_3 PF00933.16 EOO01258.1 - 4.6e-61 206.4 0.0 6e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO01258.1 - 7.3e-48 163.0 0.0 1.3e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO01258.1 - 7.3e-25 86.7 0.1 1.3e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_3 PF01494.14 EOO01259.1 - 4.4e-17 62.1 0.0 7.7e-17 61.3 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain Bac_rhamnosid PF05592.6 EOO01261.1 - 8e-94 314.6 0.1 7.3e-64 215.8 0.0 2.2 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EOO01261.1 - 8.3e-44 149.1 1.1 2.2e-43 147.7 0.0 2.1 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Tyrosinase PF00264.15 EOO01262.1 - 1.7e-45 155.9 0.2 2.5e-45 155.3 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EOO01263.1 - 2.4e-25 88.9 0.0 1.2e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Microtub_assoc PF07989.6 EOO01264.1 - 2.4e-19 68.9 6.3 2.4e-19 68.9 4.4 7.1 5 2 1 7 7 7 1 Microtubule associated Mto2_bdg PF12808.2 EOO01264.1 - 4e-08 33.2 5.0 4e-08 33.2 3.5 12.2 12 3 1 13 13 13 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EOO01264.1 - 0.022 13.9 28.9 0.38 9.8 0.3 5.9 4 3 2 7 7 7 0 Reovirus sigma C capsid protein DOG1 PF14144.1 EOO01264.1 - 0.77 9.8 4.3 0.71 9.9 0.2 3.2 2 0 0 2 2 2 0 Seed dormancy control ubiquitin PF00240.18 EOO01265.1 - 1.4e-34 117.2 0.9 2.8e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EOO01265.1 - 7.9e-29 99.2 2.1 1.6e-28 98.2 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EOO01265.1 - 5.3e-20 70.8 0.7 1e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EOO01265.1 - 8.6e-06 25.9 0.5 4e-05 23.7 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EOO01265.1 - 0.00012 21.8 0.1 0.0002 21.1 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EOO01265.1 - 0.00073 19.4 0.7 0.0015 18.3 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EOO01265.1 - 0.0043 17.1 0.6 0.006 16.7 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EOO01265.1 - 0.046 13.7 0.6 0.081 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Stig1 PF04885.8 EOO01265.1 - 0.062 13.4 0.2 0.095 12.8 0.2 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Plexin_cytopl PF08337.7 EOO01265.1 - 0.084 11.1 2.8 1.6 6.9 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 EOO01265.1 - 0.087 12.7 0.5 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 IBR domain Fer2_3 PF13085.1 EOO01265.1 - 0.25 11.1 1.2 0.49 10.2 0.6 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FA_desaturase PF00487.19 EOO01267.1 - 4e-26 92.0 23.0 7.9e-26 91.0 16.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EOO01267.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank_2 PF12796.2 EOO01268.1 - 5.4e-24 84.3 4.0 1.2e-12 47.9 0.8 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01268.1 - 5.7e-20 70.0 8.6 7.4e-07 28.6 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EOO01268.1 - 4e-19 68.5 12.2 1.5e-08 34.9 0.3 4.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO01268.1 - 4.8e-17 61.5 10.8 1.9e-07 31.1 0.2 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01268.1 - 2.7e-14 51.8 7.7 0.00041 20.3 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat Porphobil_deamC PF03900.10 EOO01268.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Prefoldin_2 PF01920.15 EOO01269.1 - 1e-21 76.6 15.2 1.3e-21 76.3 10.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EOO01269.1 - 9.9e-05 22.0 12.0 0.00038 20.0 8.3 1.8 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 EOO01269.1 - 0.00023 20.7 12.8 0.00035 20.2 1.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EOO01269.1 - 0.00067 19.3 5.7 0.001 18.7 3.9 1.3 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 EOO01269.1 - 0.0023 17.3 18.7 0.016 14.6 2.4 3.0 2 1 1 3 3 3 2 Septum formation initiator COG5 PF10392.4 EOO01269.1 - 0.0025 17.7 2.5 0.25 11.3 0.1 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Spc24 PF08286.6 EOO01269.1 - 0.0027 17.3 11.6 0.14 11.8 2.8 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Spc7 PF08317.6 EOO01269.1 - 0.0031 16.2 12.0 0.0036 16.0 8.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MIP-T3 PF10243.4 EOO01269.1 - 0.0038 15.7 1.9 0.0038 15.7 1.3 1.8 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF972 PF06156.8 EOO01269.1 - 0.0068 16.7 6.1 0.74 10.1 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Fez1 PF06818.10 EOO01269.1 - 0.0083 16.1 2.1 0.0083 16.1 1.5 2.1 2 0 0 2 2 2 1 Fez1 DivIVA PF05103.8 EOO01269.1 - 0.01 15.8 11.2 0.05 13.6 0.8 2.3 2 1 0 2 2 2 0 DivIVA protein NPV_P10 PF05531.7 EOO01269.1 - 0.014 15.6 8.7 0.12 12.6 1.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 EOO01269.1 - 0.017 15.4 13.6 0.028 14.6 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 EOO01269.1 - 0.022 14.4 13.7 0.25 11.0 3.0 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.1 EOO01269.1 - 0.023 14.1 12.3 0.08 12.3 1.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 EOO01269.1 - 0.023 14.5 1.8 0.023 14.5 1.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Scaffolding_pro PF11418.3 EOO01269.1 - 0.033 14.5 1.6 0.033 14.5 1.1 2.2 1 1 0 2 2 2 0 Phi29 scaffolding protein YtxC PF08812.6 EOO01269.1 - 0.038 13.5 3.1 0.048 13.1 2.1 1.1 1 0 0 1 1 1 0 YtxC-like family HsbA PF12296.3 EOO01269.1 - 0.061 13.1 4.1 0.73 9.6 0.2 2.4 2 1 0 2 2 2 0 Hydrophobic surface binding protein A LIF_OSM PF01291.12 EOO01269.1 - 0.065 13.1 2.0 2.3 8.1 0.1 2.1 2 0 0 2 2 2 0 LIF / OSM family ADIP PF11559.3 EOO01269.1 - 0.079 12.8 12.1 0.15 11.9 1.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 EOO01269.1 - 0.084 12.7 4.7 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 K-box PF01486.12 EOO01269.1 - 0.085 12.6 0.6 0.085 12.6 0.4 2.7 2 1 1 3 3 3 0 K-box region Occludin_ELL PF07303.8 EOO01269.1 - 0.093 13.4 7.8 0.51 11.0 1.4 2.1 2 0 0 2 2 2 0 Occludin homology domain Cortex-I_coil PF09304.5 EOO01269.1 - 0.094 12.7 10.4 0.26 11.3 1.9 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Laminin_II PF06009.7 EOO01269.1 - 0.1 12.3 6.2 1.9 8.2 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF3735 PF12537.3 EOO01269.1 - 0.12 12.4 1.6 0.13 12.3 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3735) MutS_IV PF05190.13 EOO01269.1 - 0.15 12.2 5.5 0.96 9.6 0.2 2.3 2 0 0 2 2 2 0 MutS family domain IV FliD_C PF07195.7 EOO01269.1 - 0.15 11.2 7.4 0.32 10.2 5.1 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Lzipper-MIP1 PF14389.1 EOO01269.1 - 0.2 11.7 7.6 1.2 9.2 2.0 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2507 PF10702.4 EOO01269.1 - 0.21 11.2 3.4 0.14 11.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2507) TcdA_TcdB PF12919.2 EOO01269.1 - 0.24 9.8 5.6 0.28 9.6 3.9 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain YgaB PF14182.1 EOO01269.1 - 0.24 11.6 14.1 0.068 13.4 2.5 2.9 2 1 1 3 3 3 0 YgaB-like protein DUF4164 PF13747.1 EOO01269.1 - 0.27 11.4 6.6 3.8 7.7 0.8 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) HR1 PF02185.11 EOO01269.1 - 0.33 10.7 6.8 0.64 9.7 0.2 2.5 2 1 0 2 2 2 0 Hr1 repeat CENP-F_leu_zip PF10473.4 EOO01269.1 - 0.35 10.7 12.1 1.2 9.0 3.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gon7 PF08738.5 EOO01269.1 - 0.39 10.7 7.8 1.7 8.6 1.3 2.1 2 0 0 2 2 2 0 Gon7 family CCDC155 PF14662.1 EOO01269.1 - 0.41 10.2 13.8 4.1 6.9 6.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Mnd1 PF03962.10 EOO01269.1 - 0.5 10.0 13.7 0.5 10.0 1.8 2.1 1 1 1 2 2 2 0 Mnd1 family DUF2968 PF11180.3 EOO01269.1 - 0.51 9.6 13.0 0.29 10.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 EOO01269.1 - 0.53 10.0 6.8 1.1 9.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DMAP_binding PF06464.6 EOO01269.1 - 0.56 10.8 5.7 6.9 7.3 0.1 2.5 2 1 0 2 2 2 0 DMAP1-binding Domain DUF342 PF03961.8 EOO01269.1 - 0.6 8.4 11.0 1.2 7.4 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 EOO01269.1 - 0.61 10.3 9.1 0.76 10.0 6.3 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF948 PF06103.6 EOO01269.1 - 0.66 9.8 7.9 1.1 9.2 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_27 PF13514.1 EOO01269.1 - 0.66 7.5 11.5 3.9 5.0 7.9 1.8 1 1 0 1 1 1 0 AAA domain LLC1 PF14945.1 EOO01269.1 - 0.75 10.1 4.9 5.7 7.2 0.2 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Dor1 PF04124.7 EOO01269.1 - 0.75 8.1 6.9 2.7 6.3 4.7 1.7 1 1 0 1 1 1 0 Dor1-like family V-ATPase_C PF03223.10 EOO01269.1 - 0.87 8.4 7.5 1.8 7.3 5.0 1.6 1 1 0 1 1 1 0 V-ATPase subunit C DUF4200 PF13863.1 EOO01269.1 - 0.87 9.5 14.1 0.44 10.4 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 EOO01269.1 - 0.88 9.4 14.1 1.1 9.0 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin like Sas10_Utp3 PF04000.10 EOO01269.1 - 0.9 9.7 6.9 1.3 9.3 1.2 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family FliD_N PF02465.13 EOO01269.1 - 0.94 9.8 7.2 5.3 7.4 0.5 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Rho_Binding PF08912.6 EOO01269.1 - 1 9.7 15.1 0.32 11.3 1.2 2.7 2 1 0 2 2 2 0 Rho Binding TMF_TATA_bd PF12325.3 EOO01269.1 - 1.1 9.0 9.6 2.7 7.7 2.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EOO01269.1 - 1.2 8.0 13.2 2.9 6.7 9.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 EOO01269.1 - 1.4 8.9 12.4 1.3 9.1 1.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Uds1 PF15456.1 EOO01269.1 - 1.4 8.8 6.5 4.8 7.1 4.5 1.7 1 1 0 1 1 1 0 Up-regulated During Septation DUF4140 PF13600.1 EOO01269.1 - 1.6 9.2 9.0 6.1 7.3 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Laminin_I PF06008.9 EOO01269.1 - 2.1 7.5 13.5 17 4.6 9.4 1.9 1 1 0 1 1 1 0 Laminin Domain I DUF2802 PF10975.3 EOO01269.1 - 2.2 8.1 9.8 4 7.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) CASP_C PF08172.7 EOO01269.1 - 2.3 7.1 9.1 0.65 8.9 0.8 2.1 2 0 0 2 2 2 0 CASP C terminal YlqD PF11068.3 EOO01269.1 - 2.6 8.0 18.5 1.2 9.1 3.1 2.0 1 1 1 2 2 2 0 YlqD protein Macoilin PF09726.4 EOO01269.1 - 2.9 6.0 12.5 11 4.1 8.6 1.7 1 1 0 1 1 1 0 Transmembrane protein CHD5 PF04420.9 EOO01269.1 - 2.9 7.5 7.6 1.6 8.3 0.6 2.1 2 0 0 2 2 2 0 CHD5-like protein Cep57_MT_bd PF06657.8 EOO01269.1 - 3.1 7.8 9.6 2.8 7.9 0.8 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GP41 PF00517.12 EOO01269.1 - 3.7 7.0 6.9 8 5.9 0.3 2.0 2 0 0 2 2 2 0 Retroviral envelope protein Rootletin PF15035.1 EOO01269.1 - 3.8 7.4 12.9 81 3.1 9.0 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Laps PF10169.4 EOO01269.1 - 4.1 7.6 9.4 4.5 7.5 1.7 2.1 2 0 0 2 2 2 0 Learning-associated protein BRE1 PF08647.6 EOO01269.1 - 4.3 7.3 13.5 1.1 9.2 1.9 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.1 EOO01269.1 - 4.4 6.4 15.7 21 4.2 10.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 EOO01269.1 - 6.5 6.2 7.6 17 4.9 0.2 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-H PF05837.7 EOO01269.1 - 8 6.6 13.0 3.2 7.9 1.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Val_tRNA-synt_C PF10458.4 EOO01269.1 - 8.3 6.5 12.8 5.8 7.0 1.4 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Spectrin PF00435.16 EOO01269.1 - 8.4 6.7 12.1 9.2 6.6 2.4 2.2 2 0 0 2 2 2 0 Spectrin repeat HALZ PF02183.13 EOO01269.1 - 8.9 6.1 9.5 3.1 7.5 1.3 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper Methyltransf_6 PF03737.10 EOO01270.1 - 4e-29 101.4 0.0 1.4e-28 99.6 0.0 2.0 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase adh_short_C2 PF13561.1 EOO01270.1 - 1.8e-12 47.5 0.0 2.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO01270.1 - 4e-07 30.0 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 EOO01271.1 - 0.00098 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 EOO01272.1 - 6.6e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EOO01272.1 - 2.3e-12 47.2 0.0 4.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EOO01272.1 - 9.6e-09 35.2 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DIOX_N PF14226.1 EOO01273.1 - 1.3e-26 93.3 0.2 2.1e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO01273.1 - 2.7e-21 75.6 0.0 4.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TOH_N PF12549.3 EOO01273.1 - 0.14 11.7 0.0 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal AAA PF00004.24 EOO01274.1 - 2.9e-42 143.9 0.0 5.3e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EOO01274.1 - 1.5e-28 98.4 0.4 1.1e-26 92.4 0.2 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EOO01274.1 - 2.9e-22 78.3 4.4 5e-22 77.5 2.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EOO01274.1 - 2e-06 28.6 0.1 1.6e-05 25.7 0.0 2.5 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EOO01274.1 - 7e-06 25.5 0.0 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EOO01274.1 - 7.3e-06 26.1 0.1 0.001 19.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EOO01274.1 - 1.3e-05 24.9 0.0 0.0001 22.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EOO01274.1 - 1.3e-05 24.3 0.0 2.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EOO01274.1 - 1.4e-05 25.2 0.2 0.0028 17.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.1 EOO01274.1 - 1.7e-05 24.7 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EOO01274.1 - 5.9e-05 22.5 0.1 0.061 12.7 0.1 2.8 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 EOO01274.1 - 6.8e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EOO01274.1 - 0.0002 20.3 0.0 0.0015 17.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EOO01274.1 - 0.00021 21.3 0.1 0.0024 17.9 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EOO01274.1 - 0.00022 21.0 0.0 0.00058 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EOO01274.1 - 0.00039 20.7 0.1 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EOO01274.1 - 0.00074 19.4 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EOO01274.1 - 0.0026 17.3 0.0 0.0066 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EOO01274.1 - 0.0056 15.8 0.2 0.17 10.9 0.1 2.7 1 1 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EOO01274.1 - 0.0099 15.0 0.0 0.032 13.3 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 EOO01274.1 - 0.01 14.7 0.0 0.028 13.3 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 EOO01274.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EOO01274.1 - 0.017 14.8 0.0 0.17 11.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.22 EOO01274.1 - 0.022 15.0 0.5 0.51 10.6 0.0 2.9 3 1 0 3 3 2 0 ABC transporter AAA_28 PF13521.1 EOO01274.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EOO01274.1 - 0.03 14.2 0.2 0.085 12.7 0.0 1.8 2 0 0 2 2 1 0 Torsin PhoH PF02562.11 EOO01274.1 - 0.031 13.5 0.0 0.086 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EOO01274.1 - 0.031 13.4 0.0 4.9 6.2 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.1 EOO01274.1 - 0.031 14.0 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Guanylate_kin PF00625.16 EOO01274.1 - 0.036 13.5 0.0 0.14 11.6 0.0 2.0 1 0 0 1 1 1 0 Guanylate kinase Arch_ATPase PF01637.13 EOO01274.1 - 0.039 13.6 0.8 0.54 9.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_21 PF13304.1 EOO01274.1 - 0.046 13.6 0.2 0.55 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EOO01274.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EOO01274.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EOO01274.1 - 0.09 12.2 0.0 0.33 10.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ACT_7 PF13840.1 EOO01275.1 - 1.4e-11 43.6 5.0 2.3e-09 36.6 2.1 2.2 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EOO01275.1 - 1.2e-06 27.9 1.7 7.1e-06 25.3 0.4 2.4 2 1 0 2 2 2 1 ACT domain DUF917 PF06032.7 EOO01276.1 - 2.4e-70 236.8 0.0 2.7e-37 128.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.8 EOO01276.1 - 0.0037 16.7 0.2 0.0066 15.9 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.13 EOO01276.1 - 0.0043 16.1 1.6 0.0094 15.0 0.1 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase MutL PF13941.1 EOO01276.1 - 0.062 11.6 0.8 0.1 10.9 0.6 1.4 1 1 0 1 1 1 0 MutL protein Glyco_hydro_6 PF01341.12 EOO01277.1 - 6.1e-97 324.6 2.7 7.8e-97 324.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 EOO01277.1 - 0.064 11.7 0.8 0.1 11.0 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Adeno_E3_CR2 PF02439.10 EOO01278.1 - 0.0037 16.7 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF485 PF04341.7 EOO01278.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PepSY_TM_3 PF13706.1 EOO01278.1 - 0.15 11.4 0.2 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Ank_2 PF12796.2 EOO01279.1 - 1.2e-11 44.7 0.6 1.3e-06 28.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01279.1 - 5.5e-10 38.5 5.9 0.00084 19.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EOO01279.1 - 2.6e-07 30.6 5.2 0.01 16.0 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO01279.1 - 1.4e-06 28.6 0.7 0.017 15.6 0.1 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01279.1 - 0.00016 21.5 0.1 7.5 7.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat FMN_dh PF01070.13 EOO01280.1 - 7.1e-116 386.9 0.3 8.7e-116 386.6 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EOO01280.1 - 3.9e-06 26.0 0.0 1.2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EOO01280.1 - 9.4e-06 24.9 0.6 9.4e-06 24.9 0.4 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EOO01280.1 - 0.0004 19.4 0.0 0.00063 18.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EOO01280.1 - 0.00049 19.4 0.0 0.015 14.5 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EOO01280.1 - 0.015 14.3 0.1 0.18 10.8 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EOO01280.1 - 0.12 11.3 0.1 1.2 7.9 0.0 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase Macro PF01661.16 EOO01281.1 - 0.023 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Macro domain Paramyxo_ncap PF00973.14 EOO01281.1 - 0.22 10.1 0.9 0.31 9.6 0.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein 2-Hacid_dh_C PF02826.14 EOO01283.1 - 5.4e-28 97.3 0.0 1e-27 96.4 0.0 1.5 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain JAB PF01398.16 EOO01284.1 - 1.4e-14 53.7 0.0 3.1e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EOO01284.1 - 1.3e-09 37.9 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EOO01284.1 - 8e-05 22.1 0.0 0.00023 20.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Nop PF01798.13 EOO01285.1 - 2.5e-57 192.4 0.1 4.4e-57 191.6 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EOO01285.1 - 4.1e-23 80.9 0.0 1.1e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EOO01285.1 - 1.9e-20 72.7 0.2 1.9e-20 72.7 0.1 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF3085 PF11284.3 EOO01285.1 - 0.094 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Sugar_tr PF00083.19 EOO01286.1 - 8e-37 126.8 20.8 2.2e-26 92.4 7.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01286.1 - 1.2e-06 27.4 29.4 0.00015 20.6 5.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01286.1 - 0.00062 18.2 19.1 0.0022 16.4 4.0 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein TcdB_toxin_midN PF12256.3 EOO01286.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF1993 PF09351.5 EOO01287.1 - 6.2e-52 175.7 0.0 6.9e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) RNA_pol_Rpb1_2 PF00623.15 EOO01287.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Peptidase_M28 PF04389.12 EOO01289.1 - 1.2e-19 70.7 0.1 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EOO01289.1 - 0.016 14.4 0.2 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Nicastrin Peptidase_M20 PF01546.23 EOO01289.1 - 0.033 13.6 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Glyco_hydro_18 PF00704.23 EOO01290.1 - 3.5e-101 339.0 1.3 4.1e-101 338.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PMBR PF09373.5 EOO01290.1 - 0.15 12.0 0.3 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat 2-Hacid_dh_C PF02826.14 EOO01291.1 - 1.3e-51 174.2 0.0 2.3e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EOO01291.1 - 3e-23 81.7 0.1 3.8e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EOO01291.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EOO01291.1 - 0.012 15.0 0.1 0.05 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EOO01291.1 - 0.039 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DHQ_synthase PF01761.15 EOO01292.1 - 6.7e-43 146.4 0.0 9.9e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EOO01292.1 - 1.4e-10 40.8 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PEP_mutase PF13714.1 EOO01294.1 - 4.9e-56 189.5 0.6 5.5e-56 189.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Amidohydro_2 PF04909.9 EOO01294.1 - 0.014 14.9 0.1 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase AP_endonuc_2 PF01261.19 EOO01294.1 - 0.028 13.6 0.5 2.7 7.2 0.1 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Radical_SAM PF04055.16 EOO01294.1 - 0.043 13.9 0.1 1.5 8.9 0.1 2.3 1 1 0 1 1 1 0 Radical SAM superfamily NanE PF04131.9 EOO01294.1 - 0.081 11.8 0.4 0.5 9.3 0.3 2.1 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DeoC PF01791.4 EOO01295.1 - 1.6e-34 119.2 5.2 8.1e-34 116.9 3.6 1.8 1 1 0 1 1 1 1 DeoC/LacD family aldolase MFS_1 PF07690.11 EOO01296.1 - 3.1e-36 124.8 52.6 9.4e-35 119.9 35.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily YwiC PF14256.1 EOO01296.1 - 0.0016 18.5 3.7 0.0016 18.5 2.6 3.6 3 2 0 4 4 4 1 YwiC-like protein MS_channel PF00924.13 EOO01296.1 - 0.067 12.5 1.8 0.25 10.6 1.2 2.0 1 0 0 1 1 1 0 Mechanosensitive ion channel NfeD PF01957.13 EOO01296.1 - 0.093 12.8 0.4 0.093 12.8 0.2 4.0 4 2 2 6 6 6 0 NfeD-like C-terminal, partner-binding An_peroxidase PF03098.10 EOO01297.1 - 3.8e-68 230.1 0.0 4.7e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EOO01297.1 - 0.031 12.7 0.1 0.2 10.1 0.0 1.9 2 0 0 2 2 2 0 Cytochrome P450 Methyltransf_3 PF01596.12 EOO01298.1 - 8.6e-14 51.0 0.0 1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EOO01298.1 - 1.5e-09 38.5 0.0 2.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EOO01298.1 - 0.061 12.6 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase DAO PF01266.19 EOO01299.1 - 3.9e-58 197.0 0.3 4.4e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EOO01299.1 - 0.031 13.9 0.6 0.65 9.6 0.1 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EOO01299.1 - 0.079 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.9 EOO01299.1 - 0.13 12.0 2.7 3.1 7.6 1.9 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 EOO01300.1 - 1.5e-22 80.6 0.2 1.9e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO01300.1 - 6.6e-09 35.6 0.0 4.7e-08 32.8 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO01300.1 - 2.6e-07 30.5 0.0 6.6e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EOO01301.1 - 2.4e-36 125.1 25.2 3.5e-36 124.6 17.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EOO01301.1 - 0.0063 16.0 3.9 0.0063 16.0 2.7 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Methyltransf_23 PF13489.1 EOO01302.1 - 2.5e-18 66.3 0.0 3.4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO01302.1 - 6.7e-10 39.5 0.1 2.3e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01302.1 - 7.7e-08 32.0 0.0 1.9e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO01302.1 - 3.5e-07 30.6 0.0 6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01302.1 - 7.8e-07 29.4 0.0 1.3e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO01302.1 - 5.2e-05 22.4 0.0 0.66 9.0 0.0 3.1 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EOO01302.1 - 0.00047 20.2 0.1 0.00086 19.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EOO01302.1 - 0.00056 19.0 0.0 0.0048 15.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EOO01302.1 - 0.0014 18.9 0.0 0.0051 17.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO01302.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EOO01302.1 - 0.0079 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EOO01302.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EOO01302.1 - 0.028 14.4 0.0 0.084 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EOO01302.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase adh_short PF00106.20 EOO01303.1 - 1.2e-25 90.3 0.1 2.2e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01303.1 - 1.3e-11 44.4 0.2 2.4e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO01303.1 - 2.7e-07 30.5 0.3 4.4e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EOO01303.1 - 0.0011 18.6 1.0 0.013 15.3 0.9 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1445 PF07286.7 EOO01304.1 - 1.9e-56 189.7 0.0 2.7e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) AA_permease PF00324.16 EOO01305.1 - 2.6e-108 362.4 37.6 3.2e-108 362.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO01305.1 - 3.6e-31 108.1 39.8 5.6e-31 107.5 27.6 1.2 1 0 0 1 1 1 1 Amino acid permease CSTF_C PF14304.1 EOO01306.1 - 1.1 8.6 4.1 0.39 10.0 0.5 2.0 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF3435 PF11917.3 EOO01307.1 - 3.8e-23 81.8 10.5 9.6e-14 50.9 2.4 3.6 3 1 1 4 4 4 3 Protein of unknown function (DUF3435) MutS_III PF05192.13 EOO01307.1 - 0.094 12.4 0.5 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 MutS domain III Abhydrolase_4 PF08386.5 EOO01308.1 - 5e-11 42.4 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein SNARE PF05739.14 EOO01311.1 - 8e-10 38.2 3.2 1.1e-09 37.8 2.2 1.2 1 0 0 1 1 1 1 SNARE domain DUF912 PF06024.7 EOO01311.1 - 0.0023 17.9 0.9 0.0028 17.6 0.6 1.3 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EOO01311.1 - 0.0082 15.8 2.4 0.0098 15.5 1.7 1.0 1 0 0 1 1 1 1 Rifin/stevor family DUF3792 PF12670.2 EOO01311.1 - 0.015 15.1 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF1510 PF07423.6 EOO01311.1 - 0.023 14.0 1.0 0.037 13.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3040 PF11239.3 EOO01311.1 - 0.027 14.5 0.6 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) VirB8 PF04335.8 EOO01311.1 - 0.038 13.5 0.6 0.038 13.5 0.4 1.5 2 0 0 2 2 2 0 VirB8 protein MCPsignal PF00015.16 EOO01311.1 - 0.043 13.3 1.6 0.062 12.8 1.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1282 PF06930.7 EOO01311.1 - 0.045 13.4 0.1 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2116 PF09889.4 EOO01311.1 - 0.046 13.5 0.9 0.046 13.5 0.6 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) 7tm_7 PF08395.7 EOO01311.1 - 0.047 12.6 1.0 0.068 12.1 0.1 1.6 2 0 0 2 2 2 0 7tm Chemosensory receptor ETRAMP PF09716.5 EOO01311.1 - 0.051 13.5 0.7 0.07 13.0 0.5 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF998 PF06197.8 EOO01311.1 - 0.088 12.1 0.4 0.12 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) YPEB PF14620.1 EOO01311.1 - 0.089 11.7 1.1 0.11 11.5 0.8 1.1 1 0 0 1 1 1 0 YpeB sporulation PBP1_TM PF14812.1 EOO01311.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1469 PF07332.6 EOO01311.1 - 0.11 12.2 0.4 0.11 12.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) ODV-E18 PF10717.4 EOO01311.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Chordopox_A13L PF05961.6 EOO01311.1 - 0.13 12.2 1.8 0.26 11.2 1.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3357 PF11837.3 EOO01311.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Cytochrom_B559a PF00284.15 EOO01311.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit HAUS-augmin3 PF14932.1 EOO01311.1 - 0.2 10.7 2.9 0.24 10.5 2.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2976 PF11190.3 EOO01311.1 - 0.27 10.7 2.5 1.1 8.8 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4307 PF14155.1 EOO01311.1 - 0.28 10.9 2.8 0.28 10.9 1.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Herpes_US9 PF06072.6 EOO01311.1 - 0.51 10.2 2.7 0.81 9.5 1.8 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3139 PF11337.3 EOO01311.1 - 0.91 9.8 4.0 0.42 10.9 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SseC PF04888.7 EOO01311.1 - 1.5 8.0 10.6 0.35 10.1 4.6 1.7 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family P12 PF12669.2 EOO01311.1 - 7 6.9 6.6 0.88 9.8 1.1 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family FAD_binding_4 PF01565.18 EOO01312.1 - 6.3e-10 38.6 1.4 6.3e-10 38.6 1.0 2.6 3 0 0 3 3 3 2 FAD binding domain DUF296 PF03479.10 EOO01312.1 - 0.018 14.6 0.3 0.044 13.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF296) A_deaminase PF00962.17 EOO01313.1 - 3.7e-29 101.6 0.0 6.9e-28 97.5 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase Glyco_hydro_28 PF00295.12 EOO01314.1 - 3.3e-05 23.0 9.1 0.00021 20.3 6.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_3 PF00933.16 EOO01315.1 - 2.3e-86 289.4 0.0 3.3e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO01315.1 - 4.3e-59 199.8 0.1 2.3e-58 197.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO01315.1 - 2.2e-20 72.3 0.2 1.2e-19 69.9 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain p450 PF00067.17 EOO01317.1 - 2.1e-52 178.1 0.0 3.1e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transketolase_N PF00456.16 EOO01317.1 - 8.5e-16 57.6 0.3 1.8e-14 53.3 0.2 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 EOO01317.1 - 2.2e-05 24.0 0.2 9.9e-05 21.9 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EOO01317.1 - 0.00033 19.4 0.0 0.00059 18.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Sugar_tr PF00083.19 EOO01318.1 - 1.6e-27 96.2 16.1 1.8e-27 96.0 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01318.1 - 5.4e-05 22.0 15.5 6.8e-05 21.7 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EOO01319.1 - 6e-35 120.4 0.0 6.8e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 EOO01320.1 - 7.8e-19 68.3 0.1 1.4e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.17 EOO01321.1 - 4.2e-07 30.4 0.0 9.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Phosphoprotein PF00922.12 EOO01321.1 - 0.16 11.1 0.3 4 6.5 0.0 2.6 3 0 0 3 3 3 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 EOO01323.1 - 1.1e-42 145.9 46.6 4.9e-37 127.4 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transketolase_C PF02780.15 EOO01325.1 - 2.1e-12 47.0 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain MFS_1 PF07690.11 EOO01326.1 - 2.8e-13 49.2 4.8 3.1e-13 49.1 3.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO01326.1 - 1.3e-07 30.5 1.2 1.4e-07 30.4 0.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 EOO01326.1 - 0.0018 18.6 2.7 0.018 15.4 0.1 2.1 1 1 1 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Bax1-I PF01027.15 EOO01326.1 - 1.1 8.8 7.8 0.053 13.1 0.8 1.8 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 adh_short PF00106.20 EOO01327.1 - 3e-10 40.2 0.5 4e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EOO01327.1 - 0.00011 21.7 0.1 0.00021 20.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO01327.1 - 0.00031 19.7 0.1 0.00049 19.0 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.1 EOO01327.1 - 0.0029 17.4 0.2 0.0036 17.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EOO01327.1 - 0.006 16.5 0.7 0.02 14.8 0.5 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EOO01327.1 - 0.016 14.8 0.1 0.044 13.4 0.1 1.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EOO01327.1 - 0.019 14.2 0.3 0.062 12.5 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.14 EOO01327.1 - 0.03 13.4 0.0 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EOO01327.1 - 0.068 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 EOO01328.1 - 1.3e-20 74.2 0.5 1.8e-20 73.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO01328.1 - 1.4e-08 34.6 0.1 5.1e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EOO01328.1 - 6.7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EOO01328.1 - 0.00016 21.3 0.0 0.00027 20.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 EOO01329.1 - 3.9e-05 23.2 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase AA_permease_2 PF13520.1 EOO01330.1 - 1.2e-60 205.2 45.1 1.6e-60 204.8 31.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF607 PF04678.8 EOO01330.1 - 3e-40 138.0 0.0 3e-40 138.0 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF607 AA_permease PF00324.16 EOO01330.1 - 1.8e-17 62.8 33.5 2.8e-17 62.2 23.2 1.2 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-bind_3 PF12776.2 EOO01331.1 - 6.5e-21 74.7 0.2 8.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Vfa1 PF08432.5 EOO01332.1 - 0.17 11.8 3.6 3 7.8 0.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 APH PF01636.18 EOO01333.1 - 1.4e-11 44.6 0.2 2e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2388 PF09498.5 EOO01333.1 - 0.025 14.2 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) RIO1 PF01163.17 EOO01333.1 - 0.085 12.1 0.1 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family tRNA_Me_trans PF03054.11 EOO01336.1 - 0.17 10.3 0.3 0.26 9.8 0.2 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SpoIIIAH PF12685.2 EOO01337.1 - 0.05 13.0 1.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Sugar_tr PF00083.19 EOO01339.1 - 6e-53 180.0 10.0 6.7e-53 179.8 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01339.1 - 0.0012 17.6 20.9 0.0015 17.3 13.9 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3624 PF12292.3 EOO01339.1 - 0.0068 16.7 0.7 2.2 8.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3624) Gate PF07670.9 EOO01339.1 - 0.45 10.4 7.5 1.7 8.5 5.2 2.0 1 1 0 1 1 1 0 Nucleoside recognition Alpha-L-AF_C PF06964.7 EOO01340.1 - 1e-31 110.0 0.1 1.5e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus RVT_1 PF00078.22 EOO01341.1 - 3e-11 43.0 0.0 3.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LEA_3 PF03242.8 EOO01342.1 - 0.025 14.8 0.7 0.07 13.3 0.5 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein Lebercilin PF15619.1 EOO01342.1 - 4.7 6.5 7.9 1 8.7 0.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sugar_tr PF00083.19 EOO01343.1 - 4.3e-59 200.2 18.3 4.9e-59 200.0 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01343.1 - 6.2e-08 31.7 11.3 7.7e-08 31.4 7.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily EBP PF05241.7 EOO01343.1 - 0.15 11.0 5.6 0.26 10.2 3.9 1.4 1 0 0 1 1 1 0 Emopamil binding protein MAT_Alpha1 PF04769.7 EOO01344.1 - 8.6e-32 110.0 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DUF2400 PF09674.5 EOO01345.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Barstar PF01337.13 EOO01345.1 - 0.052 13.3 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 Barstar (barnase inhibitor) Exo_endo_phos PF03372.18 EOO01346.1 - 4.4e-17 62.8 0.0 6.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EOO01346.1 - 2e-16 59.6 0.0 7.1e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase COX6A PF02046.10 EOO01347.1 - 6.1e-37 126.0 1.7 1.1e-36 125.2 1.2 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.3 EOO01347.1 - 0.07 12.6 0.1 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2933) HMG_box PF00505.14 EOO01348.1 - 4.5e-11 42.8 0.1 7.4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Macscav_rec PF03523.8 EOO01348.1 - 0.018 14.7 0.5 0.61 9.8 0.0 2.6 2 0 0 2 2 2 0 Macrophage scavenger receptor MAT_Alpha1 PF04769.7 EOO01348.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 EOO01348.1 - 0.099 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 HMG-box domain Glyco_transf_28 PF03033.15 EOO01349.1 - 8.8e-18 64.4 0.0 3.4e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EOO01349.1 - 0.00011 20.8 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EOO01349.1 - 0.016 14.8 0.0 0.052 13.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EOO01349.1 - 0.065 13.3 0.0 0.64 10.2 0.0 2.5 2 0 0 2 2 2 0 ATG C terminal domain Oest_recep PF02159.10 EOO01350.1 - 6.7 6.8 9.0 4.5 7.4 3.3 2.2 1 1 1 2 2 2 0 Oestrogen receptor Kinetochor_Ybp2 PF08568.5 EOO01351.1 - 1.2e-34 119.6 0.1 1.3e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin NTase_sub_bind PF08780.6 EOO01352.1 - 0.033 13.9 0.2 0.078 12.7 0.2 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like PAN_4 PF14295.1 EOO01353.1 - 8.3e-06 25.4 0.7 1.4e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EOO01353.1 - 0.00071 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EOO01353.1 - 0.023 14.2 0.5 0.041 13.4 0.3 1.3 1 0 0 1 1 1 0 PAN-like domain Zip PF02535.17 EOO01353.1 - 0.044 12.8 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAN_2 PF08276.6 EOO01353.1 - 0.073 12.9 0.9 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 PAN-like domain Isochorismatase PF00857.15 EOO01354.1 - 6e-18 65.3 0.0 9.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Topoisom_bac PF01131.15 EOO01355.1 - 2.5e-93 313.0 0.0 1.1e-87 294.5 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EOO01355.1 - 1.5e-11 44.1 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.15 EOO01355.1 - 0.11 10.6 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase PI3_PI4_kinase PF00454.22 EOO01356.1 - 4.7e-40 137.5 0.0 6.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EOO01356.1 - 1.2e-11 43.8 0.0 1.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 FATC domain Cullin PF00888.17 EOO01357.1 - 2.6e-129 432.4 0.1 3.7e-129 431.9 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EOO01357.1 - 1.9e-27 94.8 0.4 4.4e-27 93.7 0.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 EOO01357.1 - 0.016 14.7 0.0 0.045 13.3 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.2 EOO01357.1 - 0.035 13.7 0.0 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 MarR family adh_short PF00106.20 EOO01358.1 - 1.6e-16 60.6 0.1 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01358.1 - 2.9e-07 30.3 0.0 4.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO01358.1 - 0.00018 20.9 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO01358.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EOO01358.1 - 0.0068 16.1 0.0 0.0083 15.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TIR-like PF10137.4 EOO01358.1 - 0.008 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain COesterase PF00135.23 EOO01359.1 - 1.6e-73 248.2 0.0 3e-73 247.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO01359.1 - 7.9e-09 35.3 0.4 3.6e-08 33.2 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EOO01359.1 - 0.054 12.6 0.2 0.095 11.9 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Amidase PF01425.16 EOO01360.1 - 3.9e-53 180.8 0.2 5e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3779 PF12621.3 EOO01360.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphate metabolism protein DUF3414 PF11894.3 EOO01361.1 - 6.8e-111 371.4 0.4 8.3e-111 371.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) VCBS PF13517.1 EOO01362.1 - 2e-32 111.3 65.8 8.6e-10 38.8 3.3 8.9 4 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO01362.1 - 2.1e-10 39.9 47.3 0.032 13.9 0.0 9.2 8 0 0 8 8 8 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EOO01362.1 - 7.4e-05 22.2 10.4 0.7 9.3 0.1 5.9 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Stb3 PF10330.4 EOO01363.1 - 1.2e-38 130.6 0.0 1.9e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF3602 PF12223.3 EOO01364.1 - 2.8e-11 43.6 14.0 0.00022 21.5 1.5 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) VIT1 PF01988.14 EOO01364.1 - 0.032 13.7 0.4 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 VIT family Ku_N PF03731.10 EOO01367.1 - 3.4e-28 98.6 0.2 7.9e-28 97.3 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EOO01367.1 - 8.3e-28 97.1 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EOO01367.1 - 6.6e-14 51.8 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EOO01367.1 - 9.2e-05 22.6 0.2 0.00028 21.0 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EOO01367.1 - 0.00069 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain CH PF00307.26 EOO01369.1 - 7.7e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EOO01369.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.3 EOO01369.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain DNA_pol_A PF00476.15 EOO01370.1 - 3.2e-98 328.8 0.0 4.5e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DnaJ PF00226.26 EOO01371.1 - 1.6e-07 30.9 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EOO01371.1 - 4.1e-07 29.8 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Pam16 Oxidored_FMN PF00724.15 EOO01373.1 - 1.6e-85 287.1 0.0 1.8e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EOO01373.1 - 0.02 14.1 0.1 0.54 9.5 0.0 2.1 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Abhydrolase_6 PF12697.2 EOO01374.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EOO01375.1 - 2.4e-51 174.7 11.7 3e-51 174.4 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01375.1 - 1.2e-05 24.2 18.5 1.2e-05 24.2 12.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Atu4866 PF11512.3 EOO01375.1 - 0.13 11.9 0.0 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 DUF4131 PF13567.1 EOO01375.1 - 2.1 7.7 11.2 1.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1446 PF07287.6 EOO01376.1 - 1.1e-104 349.8 0.1 1.6e-104 349.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 EOO01376.1 - 0.043 12.7 0.0 0.086 11.7 0.0 1.5 1 0 0 1 1 1 0 LytB protein AMP-binding PF00501.23 EOO01377.1 - 6.4e-87 291.6 0.0 7.7e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO01377.1 - 1.9e-07 31.9 0.0 5.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 EOO01378.1 - 9.2e-46 154.1 1.6 8.8e-20 70.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EOO01378.1 - 9.7e-37 122.9 1.2 2.8e-06 26.8 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EOO01378.1 - 1.1e-31 108.5 2.0 8.4e-10 38.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01378.1 - 5.4e-30 100.4 0.0 0.00021 21.2 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EOO01378.1 - 5e-27 93.3 7.7 1.3e-10 41.1 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EOO01378.1 - 4.2e-14 52.0 1.2 1.4e-13 50.3 0.8 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Sigma70_ner PF04546.8 EOO01378.1 - 0.39 10.2 4.5 0.16 11.5 0.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EOO01378.1 - 2.8 7.4 6.8 4.2 6.8 4.0 1.8 2 0 0 2 2 2 0 Nucleoplasmin Sugar_tr PF00083.19 EOO01379.1 - 2.5e-98 329.6 25.2 2.8e-98 329.4 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01379.1 - 7.7e-26 90.6 23.9 7.7e-26 90.6 16.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EOO01379.1 - 2.9e-07 28.9 12.0 0.0047 15.0 2.6 3.8 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EOO01379.1 - 0.00044 18.7 28.1 0.0045 15.4 7.9 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein Aldo_ket_red PF00248.16 EOO01380.1 - 1e-27 96.7 0.2 3.3e-12 45.8 0.0 3.1 1 1 2 3 3 3 3 Aldo/keto reductase family Aldedh PF00171.17 EOO01381.1 - 1.7e-122 409.1 0.4 1.9e-122 408.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asp_Glu_race PF01177.17 EOO01381.1 - 0.088 12.7 0.1 0.99 9.2 0.0 2.2 1 1 1 2 2 2 0 Asp/Glu/Hydantoin racemase DUF1487 PF07368.6 EOO01381.1 - 0.16 11.2 0.0 1 8.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NACHT PF05729.7 EOO01382.1 - 1.7e-09 37.5 0.6 1.4e-08 34.5 0.1 2.6 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EOO01382.1 - 9e-07 29.0 0.0 9e-07 29.0 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EOO01382.1 - 1.9e-05 24.8 0.1 0.00012 22.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain Peptidase_M19 PF01244.16 EOO01383.1 - 1.3e-46 159.0 0.0 1.6e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3260 PF11658.3 EOO01383.1 - 0.17 9.9 0.1 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Pkinase PF00069.20 EOO01384.1 - 1.8e-69 233.8 0.0 2.6e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01384.1 - 9.1e-33 113.4 0.0 2e-32 112.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO01384.1 - 8.6e-06 24.9 0.0 0.00019 20.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EOO01384.1 - 0.0092 15.0 0.2 0.031 13.3 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EOO01384.1 - 0.012 15.3 8.5 0.031 13.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EOO01384.1 - 0.044 12.6 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.19 EOO01385.1 - 5.4e-24 84.5 12.7 6.1e-24 84.4 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EOO01385.1 - 0.0094 14.3 10.2 0.012 13.9 7.1 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein NfeD PF01957.13 EOO01385.1 - 1.1 9.3 5.6 1.9 8.6 1.6 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding HlyIII PF03006.15 EOO01385.1 - 3.3 7.0 9.0 0.62 9.4 3.2 1.8 1 1 0 1 1 1 0 Haemolysin-III related TFIIIC_delta PF12657.2 EOO01387.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term ALO PF04030.9 EOO01387.1 - 0.21 11.1 1.6 0.23 11.0 0.4 1.6 2 1 0 2 2 2 0 D-arabinono-1,4-lactone oxidase DAO PF01266.19 EOO01388.1 - 1.5e-45 155.6 0.0 1.7e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EOO01388.1 - 0.0057 16.4 0.0 0.058 13.1 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EOO01388.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EOO01388.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Melibiase PF02065.13 EOO01388.1 - 0.014 14.1 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 Melibiase Pyr_redox_3 PF13738.1 EOO01388.1 - 0.043 13.8 0.0 0.41 10.6 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO01388.1 - 0.056 13.3 0.1 2.1 8.1 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EOO01388.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EOO01388.1 - 0.14 12.5 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Alpha_L_fucos PF01120.12 EOO01389.1 - 3.8e-70 236.5 0.1 4.8e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EOO01389.1 - 0.0018 18.3 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 PseudoU_synth_1 PF01416.15 EOO01390.1 - 1.2e-23 83.5 0.2 3.1e-11 43.6 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase Hydantoinase_B PF02538.9 EOO01391.1 - 4.5e-129 431.0 0.0 1.9e-108 363.0 0.0 2.7 2 1 1 3 3 3 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO01391.1 - 2.4e-85 286.1 1.3 3.7e-83 278.9 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO01391.1 - 1.2e-39 135.6 2.2 1.7e-38 131.9 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CaM-KIIN PF15170.1 EOO01391.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor Peptidase_C12 PF01088.16 EOO01392.1 - 4.7e-13 48.8 0.0 5.6e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YvfG PF09628.5 EOO01392.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 YvfG protein Med22 PF06179.7 EOO01393.1 - 3.5e-16 59.1 1.3 4.2e-16 58.9 0.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Peptidase_S28 PF05577.7 EOO01393.1 - 0.052 12.1 0.0 0.09 11.3 0.0 1.3 2 0 0 2 2 2 0 Serine carboxypeptidase S28 HisKA PF00512.20 EOO01393.1 - 0.12 12.3 6.1 0.96 9.4 0.6 2.8 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain Toxin-deaminase PF14424.1 EOO01393.1 - 0.19 11.7 0.6 13 5.7 0.1 2.1 1 1 1 2 2 2 0 The BURPS668_1122 family of deaminases Pkinase PF00069.20 EOO01394.1 - 1.8e-69 233.7 0.0 2.2e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01394.1 - 1.8e-31 109.1 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EOO01394.1 - 0.0037 17.0 0.0 0.0077 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EOO01394.1 - 0.0045 16.0 0.0 0.0066 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EOO01394.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EOO01394.1 - 0.092 11.7 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family STAT1_TAZ2bind PF12162.3 EOO01395.1 - 1.8 8.0 5.0 2 7.9 1.6 2.2 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain MFS_1 PF07690.11 EOO01396.1 - 3.7e-26 91.6 19.1 4.8e-26 91.3 13.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ninjurin PF04923.7 EOO01396.1 - 0.019 14.6 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Ninjurin Herpes_IE1 PF07340.6 EOO01396.1 - 0.11 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein NicO PF03824.11 EOO01397.1 - 9.1e-45 153.1 0.2 9.1e-45 153.1 0.1 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.16 EOO01398.1 - 7.6e-51 172.8 2.2 3.8e-35 121.3 0.6 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease DUF1681 PF07933.9 EOO01400.1 - 2.5e-60 202.6 0.0 3.6e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribosomal_60s PF00428.14 EOO01400.1 - 0.11 12.8 3.1 0.25 11.7 1.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF605 PF04652.11 EOO01400.1 - 0.15 11.4 2.7 0.16 11.3 1.9 1.1 1 0 0 1 1 1 0 Vta1 like Aminotran_1_2 PF00155.16 EOO01401.1 - 3.5e-08 32.7 0.0 2.2e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class I and II Tannase PF07519.6 EOO01401.1 - 0.014 14.0 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase ETF PF01012.16 EOO01402.1 - 3.1e-36 124.5 0.3 3.8e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RRM_1 PF00076.17 EOO01403.1 - 8.1e-32 108.6 0.1 4.2e-15 55.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO01403.1 - 1.1e-24 86.1 0.0 2e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO01403.1 - 4.4e-09 36.0 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EOO01403.1 - 0.017 14.8 0.2 9.2 6.0 0.0 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.3 EOO01403.1 - 0.058 13.1 0.2 17 5.2 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 API5 PF05918.6 EOO01403.1 - 0.2 10.0 1.5 0.31 9.4 1.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Rhomboid PF01694.17 EOO01404.1 - 5.6e-34 117.2 8.7 5.6e-34 117.2 6.0 2.0 2 0 0 2 2 2 1 Rhomboid family DUF1426 PF07234.6 EOO01404.1 - 0.072 12.8 0.4 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) ABC2_membrane_5 PF13346.1 EOO01404.1 - 1.6 7.9 16.6 0.42 9.8 1.9 3.1 4 0 0 4 4 4 0 ABC-2 family transporter protein Carn_acyltransf PF00755.15 EOO01405.1 - 8.8e-178 592.0 0.0 1e-177 591.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.27 EOO01407.1 - 4.6e-27 92.8 8.8 9.1e-08 31.7 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EOO01407.1 - 4.5e-06 25.0 4.2 0.21 9.7 0.0 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EOO01407.1 - 0.022 14.5 0.0 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MARVEL PF01284.18 EOO01408.1 - 5.3e-05 23.0 19.7 7.5e-05 22.5 13.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Malic_M PF03949.10 EOO01409.1 - 9.5e-89 297.3 0.0 1.3e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EOO01409.1 - 2.4e-70 235.8 0.0 4.7e-70 234.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Rep_fac_C PF08542.6 EOO01410.1 - 9.4e-19 67.2 0.0 1.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EOO01410.1 - 2.1e-12 47.0 0.0 1.6e-10 40.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EOO01410.1 - 4.2e-12 46.4 0.0 7.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EOO01410.1 - 1.9e-07 31.0 0.0 4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO01410.1 - 1.8e-06 28.0 0.0 8.1e-05 22.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EOO01410.1 - 1.7e-05 24.0 0.0 4.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EOO01410.1 - 2.3e-05 24.5 0.1 0.036 14.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 EOO01410.1 - 3.8e-05 22.5 0.0 0.019 13.6 0.0 2.6 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EOO01410.1 - 8.1e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EOO01410.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EOO01410.1 - 0.00025 20.5 0.1 0.045 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_5 PF07728.9 EOO01410.1 - 0.0024 17.6 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EOO01410.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EOO01410.1 - 0.0026 16.9 0.0 0.035 13.2 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EOO01410.1 - 0.0034 16.9 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EOO01410.1 - 0.0055 16.1 0.0 0.05 12.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 EOO01410.1 - 0.0058 16.3 0.5 0.031 14.0 0.1 2.2 2 1 0 3 3 2 1 NTPase DEAD PF00270.24 EOO01410.1 - 0.0059 16.1 0.1 0.25 10.8 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase ArgK PF03308.11 EOO01410.1 - 0.0069 15.1 0.1 0.019 13.7 0.0 1.6 1 1 1 2 2 2 1 ArgK protein KTI12 PF08433.5 EOO01410.1 - 0.0071 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DNA_pol3_gamma3 PF12169.3 EOO01410.1 - 0.01 15.5 0.7 0.52 10.0 0.0 3.0 4 0 0 4 4 3 0 DNA polymerase III subunits gamma and tau domain III AAA_11 PF13086.1 EOO01410.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EOO01410.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EOO01410.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EOO01410.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EOO01410.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EOO01410.1 - 0.14 12.3 0.1 0.52 10.5 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Flg_bb_rod PF00460.15 EOO01410.1 - 0.65 9.7 3.2 14 5.5 0.5 2.6 2 0 0 2 2 2 0 Flagella basal body rod protein Saccharop_dh PF03435.13 EOO01411.1 - 4.9e-131 437.2 0.0 5.6e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EOO01411.1 - 6e-05 23.1 0.4 9.2e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EOO01411.1 - 0.0004 20.4 0.1 0.00066 19.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EOO01411.1 - 0.0018 17.6 1.3 0.018 14.4 0.2 2.6 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_3 PF03447.11 EOO01411.1 - 0.032 14.6 0.3 0.057 13.8 0.2 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EOO01411.1 - 0.043 14.3 0.1 0.078 13.4 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Bax1-I PF01027.15 EOO01412.1 - 2.6 7.5 13.9 0.68 9.5 4.0 2.4 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 EOO01412.1 - 4.7 5.8 21.7 19 3.8 14.3 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily Kelch_5 PF13854.1 EOO01413.1 - 4.6e-10 39.2 6.4 7.7e-09 35.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EOO01413.1 - 0.011 15.4 2.3 0.46 10.3 0.5 3.3 2 1 0 2 2 2 0 Galactose oxidase, central domain SKG6 PF08693.5 EOO01413.1 - 0.085 12.1 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_3 PF13415.1 EOO01413.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF4243 PF14027.1 EOO01414.1 - 3e-85 286.5 3.3 7.4e-84 281.9 2.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) DUF2607 PF10795.4 EOO01414.1 - 0.0015 18.3 0.0 0.0043 16.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2607) WSC PF01822.14 EOO01415.1 - 9.9e-55 182.4 52.4 2.4e-20 72.2 6.7 4.0 4 0 0 4 4 4 3 WSC domain peroxidase PF00141.18 EOO01415.1 - 5.5e-25 88.1 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acetyltransf_1 PF00583.19 EOO01416.1 - 0.046 13.7 0.1 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EOO01416.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EOO01416.1 - 0.093 12.3 0.0 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cpn10 PF00166.16 EOO01417.1 - 3.6e-27 94.1 0.0 4.1e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Exo70 PF03081.10 EOO01418.1 - 6.4e-71 239.0 0.0 1.2e-70 238.2 0.0 1.4 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 EOO01418.1 - 0.013 15.3 6.0 4.4 7.1 0.1 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 EOO01418.1 - 2.8 7.0 10.1 8 5.6 0.1 3.6 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 EOO01418.1 - 3.7 7.0 6.4 1 8.8 0.1 2.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain BCIP PF13862.1 EOO01419.1 - 1.2e-66 223.9 0.1 1.5e-66 223.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Csm1 PF12539.3 EOO01420.1 - 1.8e-26 92.4 0.1 4.7e-26 91.0 0.0 1.8 2 1 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 ERM PF00769.14 EOO01420.1 - 3.5e-05 23.4 9.3 4.9e-05 22.9 6.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Phlebovirus_NSM PF07246.6 EOO01420.1 - 0.0014 17.8 5.4 0.0018 17.4 3.7 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M TMF_DNA_bd PF12329.3 EOO01420.1 - 0.0022 17.7 5.1 0.0022 17.7 3.6 3.0 2 1 2 4 4 3 1 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.7 EOO01420.1 - 0.0031 16.9 19.8 0.0054 16.1 10.6 2.5 2 1 1 3 3 2 1 PspA/IM30 family Snf7 PF03357.16 EOO01420.1 - 0.0096 15.3 9.5 0.015 14.6 6.6 1.2 1 0 0 1 1 1 1 Snf7 ADIP PF11559.3 EOO01420.1 - 0.011 15.6 8.5 0.021 14.7 5.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BBP1_C PF15272.1 EOO01420.1 - 0.014 14.9 3.4 0.018 14.6 2.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal FimP PF09766.4 EOO01420.1 - 0.018 14.1 6.1 0.023 13.7 4.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein AAA_13 PF13166.1 EOO01420.1 - 0.025 13.0 7.5 0.033 12.6 5.2 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EOO01420.1 - 0.027 12.3 1.3 0.03 12.1 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.8 EOO01420.1 - 0.052 11.6 8.4 0.068 11.2 5.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HlyD_2 PF12700.2 EOO01420.1 - 0.059 12.5 2.4 0.078 12.1 1.6 1.3 1 0 0 1 1 1 0 HlyD family secretion protein FemAB PF02388.11 EOO01420.1 - 0.059 12.0 5.9 0.079 11.6 4.1 1.2 1 0 0 1 1 1 0 FemAB family Rootletin PF15035.1 EOO01420.1 - 0.082 12.8 8.6 0.14 12.1 6.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 EOO01420.1 - 0.088 11.2 3.4 0.11 10.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF812 PF05667.6 EOO01420.1 - 0.091 11.2 7.4 0.14 10.6 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fmp27_WPPW PF10359.4 EOO01420.1 - 0.093 11.1 4.0 0.12 10.8 2.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 EOO01420.1 - 0.11 11.6 2.0 0.14 11.2 1.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein YvrJ PF12841.2 EOO01420.1 - 0.12 11.6 0.2 0.38 10.0 0.1 1.9 1 0 0 1 1 1 0 YvrJ protein family AAA_27 PF13514.1 EOO01420.1 - 0.13 9.8 11.6 0.16 9.6 8.1 1.0 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EOO01420.1 - 0.14 11.6 7.2 0.34 10.4 4.8 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EOO01420.1 - 0.15 10.7 8.7 0.23 10.0 6.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3209 PF11483.3 EOO01420.1 - 0.15 12.4 2.2 0.37 11.1 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) Fib_alpha PF08702.5 EOO01420.1 - 0.15 12.1 4.7 0.27 11.3 3.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EOO01420.1 - 0.16 12.0 13.4 0.18 11.8 5.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.6 EOO01420.1 - 0.18 11.0 1.1 0.25 10.5 0.7 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4407 PF14362.1 EOO01420.1 - 0.18 10.6 10.9 0.24 10.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC37_N PF03234.9 EOO01420.1 - 0.24 11.6 4.7 0.36 11.1 3.2 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Dor1 PF04124.7 EOO01420.1 - 0.26 9.6 5.8 0.37 9.2 4.0 1.2 1 0 0 1 1 1 0 Dor1-like family TPR_MLP1_2 PF07926.7 EOO01420.1 - 0.31 10.7 16.3 0.19 11.4 9.6 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AATF-Che1 PF13339.1 EOO01420.1 - 0.4 10.8 7.2 0.75 9.9 4.5 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Cast PF10174.4 EOO01420.1 - 0.55 8.2 13.3 13 3.7 2.9 2.0 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone TBCA PF02970.11 EOO01420.1 - 0.77 9.8 6.7 0.19 11.8 1.3 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A IncA PF04156.9 EOO01420.1 - 0.8 9.2 9.9 1.4 8.5 5.8 1.9 1 1 1 2 2 2 0 IncA protein Vfa1 PF08432.5 EOO01420.1 - 0.95 9.4 7.7 1.4 8.8 5.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAS PF13851.1 EOO01420.1 - 0.97 8.5 11.1 1.1 8.4 6.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EOO01420.1 - 1 9.2 14.3 1.9 8.3 9.9 1.4 1 0 0 1 1 1 0 Tropomyosin like Phage_GP20 PF06810.6 EOO01420.1 - 1.5 8.2 11.1 6.9 6.0 7.7 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 FliD_N PF02465.13 EOO01420.1 - 2.2 8.7 14.9 1.7 9.0 8.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FUSC PF04632.7 EOO01420.1 - 2.3 6.5 4.4 3 6.1 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 EOO01420.1 - 2.3 7.0 10.2 3.6 6.4 6.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EOO01420.1 - 2.7 6.9 11.5 3.5 6.5 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EOO01420.1 - 4.8 7.5 6.9 26 5.2 4.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 EOO01420.1 - 6.7 6.8 10.8 2.5 8.2 0.4 3.1 2 1 1 3 3 3 0 Central kinetochore-associated Macoilin PF09726.4 EOO01420.1 - 7 4.8 10.2 9.2 4.4 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Phage_lysis PF03245.8 EOO01420.1 - 7.1 6.6 13.1 2.7e+02 1.5 9.1 2.4 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein DivIVA PF05103.8 EOO01420.1 - 7.4 6.6 13.9 1.3 9.0 2.6 2.3 1 1 1 2 2 2 0 DivIVA protein SlyX PF04102.7 EOO01420.1 - 7.6 6.9 8.7 1.1 9.6 0.3 3.0 2 1 2 4 4 3 0 SlyX DUF4140 PF13600.1 EOO01420.1 - 8.5 6.8 9.4 2.9 8.3 1.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 EOO01420.1 - 9 5.9 10.4 4.9 6.7 2.8 1.7 1 1 1 2 2 2 0 Mnd1 family Bap31 PF05529.7 EOO01420.1 - 9.1 5.6 9.5 17 4.7 5.9 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Cupin_1 PF00190.17 EOO01421.1 - 2.9e-10 39.7 0.1 4.8e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EOO01421.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 Cupin domain PfkB PF00294.19 EOO01422.1 - 1e-14 54.4 0.0 5.8e-09 35.5 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase LCM PF04072.9 EOO01423.1 - 2.9e-24 85.6 0.1 5.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF572 PF04502.8 EOO01424.1 - 1.4e-77 261.1 9.3 1.6e-77 260.8 6.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EOO01424.1 - 0.019 14.8 0.3 0.062 13.1 0.2 1.8 1 1 0 1 1 1 0 Benyvirus 14KDa protein DUF4661 PF15576.1 EOO01424.1 - 1.5 8.4 5.1 2.3 7.8 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Mito_carr PF00153.22 EOO01425.1 - 0.0029 17.2 0.2 0.2 11.3 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial carrier protein CorA PF01544.13 EOO01425.1 - 0.086 11.8 0.6 0.15 11.0 0.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1418 PF07214.7 EOO01425.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Fungal_trans PF04082.13 EOO01426.1 - 3.5e-39 134.2 1.1 3.5e-39 134.2 0.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain BCDHK_Adom3 PF10436.4 EOO01427.1 - 1.3e-33 115.8 0.1 1.5e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF2999 PF11212.3 EOO01427.1 - 0.11 12.5 0.1 2 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) F-box-like PF12937.2 EOO01428.1 - 3.5e-07 29.8 1.0 5.3e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EOO01428.1 - 2.2e-06 27.1 0.2 8.2e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 EOO01428.1 - 0.015 14.8 16.4 0.18 11.4 2.2 3.8 4 0 0 4 4 4 0 Ubiquitin interaction motif WD40 PF00400.27 EOO01428.1 - 0.03 14.2 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat UQ_con PF00179.21 EOO01429.1 - 7.6e-52 174.4 0.0 8.6e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO01429.1 - 8.5e-07 28.7 0.0 9.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO01429.1 - 0.026 14.3 0.2 0.054 13.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain EMP24_GP25L PF01105.19 EOO01430.1 - 3.5e-46 157.2 1.9 3.9e-46 157.0 1.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4428 PF14471.1 EOO01431.1 - 0.015 15.0 0.2 6.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Pinin_SDK_N PF04697.8 EOO01432.1 - 0.25 11.3 3.1 0.23 11.5 1.0 1.6 1 1 0 1 1 1 0 pinin/SDK conserved region CAP_N PF01213.14 EOO01434.1 - 9.6e-83 278.0 28.3 5.7e-82 275.4 19.6 2.8 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EOO01434.1 - 3.1e-54 182.6 3.9 4.4e-54 182.1 2.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EOO01434.1 - 0.18 11.2 2.1 0.7 9.3 1.3 1.8 1 1 0 1 1 1 0 Tubulin binding cofactor C TauD PF02668.11 EOO01435.1 - 7.8e-36 124.0 0.1 1e-35 123.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MoeA_N PF03453.12 EOO01436.1 - 5.2e-36 123.4 3.8 7.4e-36 122.9 2.6 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EOO01436.1 - 2.5e-31 108.0 0.2 6e-31 106.7 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.10 EOO01436.1 - 0.0002 21.2 0.1 0.0033 17.3 0.0 2.8 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) Serinc PF03348.10 EOO01437.1 - 1.4e-174 580.8 8.6 1.8e-174 580.5 5.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Histone PF00125.19 EOO01438.1 - 8.6e-09 35.4 0.1 1e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RP-C_C PF11800.3 EOO01438.1 - 0.067 12.8 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Asparaginase PF00710.15 EOO01439.1 - 1.8e-94 316.1 0.0 2.6e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 EOO01439.1 - 3.5e-15 54.9 0.2 2.2e-06 27.1 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EOO01439.1 - 6.6e-15 55.2 0.5 1.3e-14 54.2 0.4 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EOO01439.1 - 3.1e-11 43.1 0.1 2.3e-07 30.8 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO01439.1 - 5.9e-10 39.3 0.2 5e-06 26.8 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01439.1 - 5.1e-07 29.3 0.2 0.0069 16.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat CN_hydrolase PF00795.17 EOO01440.1 - 1.7e-12 47.0 0.0 1.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Thiolase_N PF00108.18 EOO01441.1 - 6.3e-94 313.8 0.7 9.6e-94 313.2 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EOO01441.1 - 7e-38 128.8 0.9 7e-38 128.8 0.6 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EOO01441.1 - 0.00023 20.7 1.0 0.00095 18.7 0.6 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HypA PF01155.14 EOO01442.1 - 0.066 12.9 8.3 0.3 10.7 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EOO01442.1 - 1.5 8.7 14.6 0.46 10.3 1.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 EOO01442.1 - 2.1 8.1 16.7 2 8.2 0.2 3.8 3 1 0 3 3 3 0 zinc-RING finger domain Ist1 PF03398.9 EOO01443.1 - 2.6e-66 222.0 1.3 5.5e-66 221.0 0.9 1.6 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIID-18kDa PF02269.11 EOO01443.1 - 1.2e-24 85.9 0.5 1.7e-23 82.1 0.0 2.9 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 EOO01443.1 - 0.062 12.4 0.8 0.12 11.5 0.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FUSC PF04632.7 EOO01443.1 - 0.6 8.4 1.9 0.92 7.8 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_transf_15 PF01793.11 EOO01444.1 - 3.5e-130 433.7 8.8 4.2e-130 433.5 6.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NAD_kinase PF01513.16 EOO01445.1 - 7.7e-67 225.0 0.0 1.2e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase IF3_C PF00707.17 EOO01445.1 - 0.031 14.0 0.6 0.072 12.8 0.2 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Sugar_tr PF00083.19 EOO01446.1 - 8.5e-35 120.1 6.7 1.1e-26 93.4 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01446.1 - 8.2e-05 21.4 8.1 8.4e-05 21.4 4.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily RSS_P20 PF11757.3 EOO01446.1 - 0.02 15.0 0.1 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like PIH1 PF08190.7 EOO01447.1 - 0.39 10.1 2.6 0.76 9.1 1.8 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 adh_short_C2 PF13561.1 EOO01448.1 - 2.6e-24 86.3 0.6 7e-24 84.9 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO01448.1 - 3.3e-21 75.9 1.1 6e-21 75.0 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01448.1 - 6.4e-07 29.2 2.3 6.4e-06 25.9 1.6 2.1 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EOO01448.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EOO01448.1 - 0.0046 16.7 0.9 0.025 14.2 0.3 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Eno-Rase_NADH_b PF12242.3 EOO01448.1 - 0.007 16.1 0.5 0.018 14.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EOO01448.1 - 0.0085 15.5 0.1 0.74 9.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EOO01448.1 - 0.012 16.0 0.5 0.022 15.1 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EOO01448.1 - 0.015 14.9 0.4 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 EOO01448.1 - 0.048 13.2 0.2 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 EOO01448.1 - 0.057 13.4 0.1 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding PGA2 PF07543.7 EOO01449.1 - 1.6e-43 147.8 6.5 1.8e-43 147.7 4.5 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 IPP-2 PF04979.9 EOO01449.1 - 0.52 10.5 6.8 0.73 10.0 4.7 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DDRGK PF09756.4 EOO01449.1 - 1 8.7 14.2 1.5 8.2 9.9 1.1 1 0 0 1 1 1 0 DDRGK domain SLY PF12485.3 EOO01449.1 - 7.2 6.8 7.9 22 5.2 5.5 1.7 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein POT1 PF02765.12 EOO01450.1 - 1.7e-10 40.9 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 IF4E PF01652.13 EOO01451.1 - 8.4e-53 178.2 0.0 1.3e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_L4 PF00573.17 EOO01452.1 - 1.8e-38 131.8 0.1 2.5e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EOO01452.1 - 2.6e-29 100.9 0.7 2.6e-29 100.9 0.5 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PigN PF04987.9 EOO01453.1 - 5.9e-119 397.5 28.4 1.2e-65 221.9 9.5 2.3 1 1 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EOO01453.1 - 1.1e-11 44.7 0.7 7.6e-10 38.6 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EOO01453.1 - 1.3e-09 37.7 0.2 1.9e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EOO01453.1 - 0.00039 19.8 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Kinesin PF00225.18 EOO01454.1 - 5.8e-113 376.9 0.2 1.4e-112 375.7 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain AAA_25 PF13481.1 EOO01454.1 - 1.1 8.6 4.5 8 5.8 0.3 3.7 4 0 0 4 4 4 0 AAA domain MTHFR PF02219.12 EOO01455.1 - 1.3e-100 336.1 0.0 2e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase adh_short PF00106.20 EOO01457.1 - 1.8e-21 76.7 2.0 9.4e-21 74.4 0.5 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO01457.1 - 9.8e-13 48.1 0.1 1.6e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO01457.1 - 4.4e-07 29.5 0.0 6.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO01457.1 - 0.033 14.1 0.7 0.085 12.8 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding SWIRM PF04433.12 EOO01458.1 - 4.8e-35 119.5 0.0 1e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EOO01458.1 - 1e-07 31.8 0.1 2.4e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EOO01458.1 - 2e-05 24.5 0.1 6.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.3 EOO01458.1 - 0.0087 15.8 3.3 0.022 14.4 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Metallophos PF00149.23 EOO01459.1 - 2.3e-25 89.1 0.0 1.9e-16 60.0 0.1 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Pet127 PF08634.5 EOO01460.1 - 2.3e-93 312.3 1.4 2.3e-93 312.3 1.0 1.7 2 0 0 2 2 2 1 Mitochondrial protein Pet127 CPL PF08144.6 EOO01460.1 - 0.071 12.9 0.7 0.26 11.1 0.2 2.0 2 0 0 2 2 2 0 CPL (NUC119) domain CPSase_sm_chain PF00988.17 EOO01461.1 - 6e-46 155.1 0.0 9.1e-46 154.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EOO01461.1 - 1.2e-45 155.3 0.0 1.7e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EOO01461.1 - 1.8e-06 27.5 0.1 0.00024 20.5 0.1 2.8 1 1 0 1 1 1 1 Peptidase C26 Septin PF00735.13 EOO01462.1 - 9.2e-116 385.7 0.2 9.2e-116 385.7 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EOO01462.1 - 6.1e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EOO01462.1 - 2.8e-06 26.8 0.2 5.7e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EOO01462.1 - 1.1e-05 24.7 0.0 2.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EOO01462.1 - 0.0023 18.3 0.1 0.0081 16.6 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EOO01462.1 - 0.0034 16.9 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EOO01462.1 - 0.0038 17.3 0.4 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EOO01462.1 - 0.0066 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EOO01462.1 - 0.0072 15.1 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EOO01462.1 - 0.011 15.2 0.9 0.017 14.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.7 EOO01462.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EOO01462.1 - 0.018 14.4 0.5 0.054 12.8 0.4 1.8 1 1 0 1 1 1 0 Ras family T2SE PF00437.15 EOO01462.1 - 0.036 12.9 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 EOO01462.1 - 0.039 13.5 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EOO01462.1 - 0.041 14.1 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EOO01462.1 - 0.068 12.6 0.3 2.8 7.4 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EOO01462.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EOO01462.1 - 0.083 11.8 1.5 0.14 11.0 1.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF2968 PF11180.3 EOO01462.1 - 0.089 12.1 6.3 0.24 10.7 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ArgK PF03308.11 EOO01462.1 - 0.092 11.5 2.7 0.78 8.4 0.0 2.9 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 EOO01462.1 - 0.099 12.4 7.9 0.68 9.7 0.1 3.1 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EOO01462.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.1 EOO01462.1 - 0.13 12.2 2.7 0.35 10.8 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Ribosomal_L6e PF01159.14 EOO01462.1 - 0.23 11.7 5.6 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Myc-LZ PF02344.10 EOO01462.1 - 0.34 10.5 6.6 0.22 11.1 0.5 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain IGPD PF00475.13 EOO01463.1 - 4.1e-60 201.8 0.5 5.6e-60 201.4 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF2437 PF10370.4 EOO01464.1 - 0.48 10.8 2.7 3.6 8.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF2437) ArfGap PF01412.13 EOO01465.1 - 1.7e-32 111.6 0.1 2.9e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CD99L2 PF12301.3 EOO01466.1 - 0.059 13.0 3.2 0.21 11.2 0.0 2.9 2 1 1 3 3 3 0 CD99 antigen like protein 2 Pkinase PF00069.20 EOO01467.1 - 6.1e-30 104.2 0.0 9.1e-30 103.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01467.1 - 1.4e-08 34.1 0.0 6.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EOO01467.1 - 0.0023 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family adh_short PF00106.20 EOO01468.1 - 2e-11 44.0 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01468.1 - 3.3e-05 23.6 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PhoD PF09423.5 EOO01469.1 - 7.9e-54 182.9 0.0 2e-28 99.1 0.0 2.2 1 1 1 2 2 2 2 PhoD-like phosphatase LRR_9 PF14580.1 EOO01470.1 - 2e-51 174.0 0.3 4.4e-51 172.9 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EOO01470.1 - 1.4e-09 37.5 6.2 6.1e-06 25.8 1.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EOO01470.1 - 2.1e-09 36.7 4.6 8.1e-05 22.1 0.1 4.4 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) DUF4349 PF14257.1 EOO01470.1 - 0.011 14.9 2.7 0.018 14.3 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_7 PF13504.1 EOO01470.1 - 0.027 14.6 1.7 34 5.2 0.1 4.9 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EOO01470.1 - 0.081 13.0 0.0 1.1e+02 3.4 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 EOO01470.1 - 0.15 12.1 6.6 20 5.7 0.4 5.1 5 1 1 6 6 6 0 Leucine Rich Repeat PspB PF06667.7 EOO01470.1 - 0.17 11.8 1.3 0.59 10.0 0.9 1.9 1 0 0 1 1 1 0 Phage shock protein B RHH_1 PF01402.16 EOO01470.1 - 0.2 11.5 1.8 0.54 10.2 0.4 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family zf-C2H2_4 PF13894.1 EOO01471.1 - 0.014 15.6 0.5 0.014 15.6 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Vps51 PF08700.6 EOO01473.1 - 1.5e-16 60.0 3.3 1.5e-16 60.0 2.3 2.3 3 0 0 3 3 3 1 Vps51/Vps67 TSC22 PF01166.13 EOO01473.1 - 0.036 14.0 0.4 9.5 6.2 0.1 3.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Sec5 PF15469.1 EOO01473.1 - 0.037 13.7 7.5 0.53 9.9 1.7 2.7 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF2383 PF09537.5 EOO01473.1 - 0.11 12.8 4.7 0.2 11.9 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Thioredoxin PF00085.15 EOO01474.1 - 4.3e-60 199.8 0.0 7.9e-30 102.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EOO01474.1 - 3.1e-25 88.6 1.6 4.7e-25 88.0 0.6 1.7 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EOO01474.1 - 2.6e-19 69.4 0.0 9.8e-09 35.3 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EOO01474.1 - 2.6e-13 49.9 0.0 1.3e-05 25.1 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EOO01474.1 - 1.4e-12 47.4 0.0 7e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EOO01474.1 - 9.7e-09 34.9 0.1 0.0054 16.4 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EOO01474.1 - 7.8e-06 25.4 0.2 0.029 13.9 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EOO01474.1 - 2.9e-05 23.6 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 EOO01474.1 - 0.00015 21.7 1.5 0.58 10.1 0.0 3.1 2 2 1 3 3 3 2 Thioredoxin ERp29_N PF07912.8 EOO01474.1 - 0.00048 20.0 0.4 0.0093 15.8 0.0 2.8 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EOO01474.1 - 0.0075 16.0 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 EOO01474.1 - 0.014 15.4 0.1 8 6.5 0.0 2.8 2 1 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.1 EOO01474.1 - 0.026 14.6 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain TraF PF13728.1 EOO01474.1 - 0.028 13.9 0.0 0.27 10.7 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein WSC PF01822.14 EOO01475.1 - 2.2e-34 117.2 21.3 3.7e-18 65.2 2.0 2.1 2 0 0 2 2 2 2 WSC domain Cys_Met_Meta_PP PF01053.15 EOO01476.1 - 4.4e-118 393.9 0.0 5e-118 393.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EOO01476.1 - 0.00065 18.7 0.1 0.00094 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II POTRA_2 PF08479.6 EOO01476.1 - 0.01 15.4 0.0 0.04 13.5 0.0 1.9 2 0 0 2 2 2 0 POTRA domain, ShlB-type NIR_SIR_ferr PF03460.12 EOO01476.1 - 0.057 13.0 0.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Exo_endo_phos PF03372.18 EOO01477.1 - 2.2e-27 96.6 0.8 3.4e-27 95.9 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EOO01477.1 - 0.034 13.9 0.2 0.37 10.5 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DKCLD PF08068.7 EOO01478.1 - 1e-29 102.1 0.1 6.4e-29 99.6 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EOO01478.1 - 1.3e-23 83.8 0.1 5.9e-21 75.1 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EOO01478.1 - 2.3e-20 72.0 0.5 4.3e-20 71.2 0.3 1.5 1 0 0 1 1 1 1 PUA domain RR_TM4-6 PF06459.7 EOO01478.1 - 9.3 6.0 7.4 13 5.6 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PGAP1 PF07819.8 EOO01479.1 - 8.2e-90 300.3 0.0 1e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EOO01479.1 - 5.4e-07 29.4 0.0 9.3e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO01479.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO01479.1 - 0.0046 16.5 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EOO01479.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Putative esterase DUF676 PF05057.9 EOO01479.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 EOO01479.1 - 0.065 11.9 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF915 PF06028.6 EOO01479.1 - 0.068 12.2 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EOO01479.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Metallophos PF00149.23 EOO01480.1 - 2.9e-44 150.8 1.0 3.7e-44 150.5 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tau95 PF09734.4 EOO01481.1 - 6.8e-58 196.4 0.0 8.8e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH_32 PF13565.1 EOO01481.1 - 0.045 14.5 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Cwf_Cwc_15 PF04889.7 EOO01481.1 - 0.21 11.2 9.6 0.32 10.6 5.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EOO01481.1 - 4.6 5.0 19.1 6.1 4.6 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family EBP PF05241.7 EOO01482.1 - 4.8e-70 234.5 6.0 5.9e-70 234.2 4.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF788 PF05620.6 EOO01482.1 - 2.3 8.0 6.1 0.43 10.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3302 PF11742.3 EOO01482.1 - 3.6 7.5 7.3 1.7 8.5 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3302) WD40 PF00400.27 EOO01484.1 - 5.4e-28 95.8 5.7 3.2e-06 26.7 0.9 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EOO01484.1 - 0.00052 19.5 3.0 0.0017 17.8 0.8 2.4 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.16 EOO01484.1 - 0.016 14.6 0.4 4.7 6.9 0.1 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.1 EOO01484.1 - 0.036 14.3 11.9 8.6 6.7 0.1 5.2 4 1 1 5 5 5 0 PQQ-like domain Gp5_C PF06715.7 EOO01484.1 - 0.075 12.9 0.5 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) SLAC1 PF03595.12 EOO01485.1 - 1.6e-59 201.2 31.3 2.3e-59 200.6 21.7 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel Radical_SAM PF04055.16 EOO01485.1 - 5e-24 85.3 0.1 9.3e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EOO01485.1 - 2.5e-23 81.9 0.0 5.6e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EOO01485.1 - 3.5e-06 27.0 0.1 2.1e-05 24.5 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin CENP-S PF15630.1 EOO01486.1 - 6.3e-33 112.7 0.0 1.2e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EOO01486.1 - 0.048 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GFA PF04828.9 EOO01487.1 - 1.1e-15 57.3 5.0 4.9e-07 29.6 0.1 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EOO01487.1 - 0.011 15.1 1.1 0.011 15.1 0.8 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EOO01487.1 - 0.016 14.7 6.6 0.61 9.6 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Rsm1 PF08600.5 EOO01487.1 - 0.26 11.1 1.6 0.79 9.6 0.3 2.1 2 0 0 2 2 2 0 Rsm1-like Nudix_N_2 PF14803.1 EOO01487.1 - 0.33 10.6 7.2 1.2 8.8 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal zf-CSL PF05207.8 EOO01487.1 - 1.7 8.2 12.8 0.4 10.2 1.6 3.0 3 0 0 3 3 3 0 CSL zinc finger DEC-1_N PF04625.8 EOO01488.1 - 8.5 4.9 15.3 1.2 7.7 7.6 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region FMO-like PF00743.14 EOO01489.1 - 8.3e-40 136.4 0.0 2.6e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EOO01489.1 - 4.5e-17 62.7 0.0 1.2e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO01489.1 - 8.8e-15 54.8 0.0 3.6e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EOO01489.1 - 3.2e-12 46.0 1.0 4e-10 39.1 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EOO01489.1 - 9.4e-11 41.9 0.0 1.2e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO01489.1 - 9.7e-08 31.2 0.0 0.021 13.7 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO01489.1 - 3.2e-06 27.0 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EOO01489.1 - 1e-05 24.7 0.1 0.00028 20.0 0.0 2.4 3 0 0 3 3 3 1 Thi4 family TrkA_N PF02254.13 EOO01489.1 - 0.00041 20.3 0.0 0.33 10.9 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain FAD_binding_2 PF00890.19 EOO01489.1 - 0.0014 17.6 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EOO01489.1 - 0.0017 17.4 0.1 0.011 14.7 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.19 EOO01489.1 - 0.002 17.2 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Strep_67kDa_ant PF06100.6 EOO01489.1 - 0.0038 15.6 0.1 0.022 13.1 0.0 1.9 2 0 0 2 2 2 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_7 PF13241.1 EOO01489.1 - 0.0095 16.1 0.0 5.6 7.2 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding FMN_red PF03358.10 EOO01489.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase HI0933_like PF03486.9 EOO01489.1 - 0.02 13.3 0.1 0.29 9.5 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.22 EOO01489.1 - 0.056 13.8 1.3 2.4 8.6 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EOO01489.1 - 0.067 13.2 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EOO01489.1 - 0.31 9.8 1.8 3.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2993 PF11209.3 EOO01490.1 - 0.018 14.9 0.1 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) CM_2 PF01817.16 EOO01491.1 - 1.6e-08 34.5 0.1 2e-05 24.5 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II Mak16 PF04874.9 EOO01491.1 - 0.043 13.8 1.0 0.14 12.2 0.1 2.3 3 0 0 3 3 3 0 Mak16 protein C-terminal region DUF3864 PF12980.2 EOO01491.1 - 0.044 13.9 0.7 1.2 9.4 0.2 2.6 2 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) WD40 PF00400.27 EOO01492.1 - 4.4e-54 178.5 25.5 5e-12 45.1 0.0 12.0 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 EOO01492.1 - 2.6e-27 94.9 0.0 3.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EOO01492.1 - 6.3e-06 26.0 0.5 0.17 11.5 0.0 6.0 6 2 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EOO01492.1 - 0.0057 15.7 0.1 8.9 5.3 0.0 3.9 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EOO01492.1 - 0.017 13.2 0.5 2.1 6.3 0.2 3.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SKIP_SNW PF02731.10 EOO01493.1 - 3.8e-67 224.6 4.8 3.8e-67 224.6 3.4 2.8 3 0 0 3 3 3 1 SKIP/SNW domain IBR PF01485.16 EOO01494.1 - 0.12 12.2 1.6 0.21 11.4 1.1 1.3 1 0 0 1 1 1 0 IBR domain USP7_ICP0_bdg PF12436.3 EOO01495.1 - 1.4e-85 286.5 0.0 2.2e-84 282.6 0.0 2.5 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EOO01495.1 - 9.9e-56 188.8 1.9 3.2e-55 187.1 1.5 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EOO01495.1 - 1.8e-54 184.3 14.1 7.8e-52 175.7 2.7 5.4 5 1 0 5 5 5 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EOO01495.1 - 1.2e-26 93.8 0.1 1.9e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EOO01495.1 - 7.4e-14 52.0 0.0 4e-13 49.6 0.0 2.3 1 0 0 1 1 1 1 MATH domain TPR_12 PF13424.1 EOO01496.1 - 0.0038 17.1 0.0 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 EOO01496.1 - 0.0082 16.0 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EOO01496.1 - 0.056 13.2 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EOO01496.1 - 0.3 11.0 1.5 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11 PF00298.14 EOO01497.1 - 2.3e-24 85.3 0.0 2.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF2823 PF11034.3 EOO01498.1 - 2e-34 117.5 10.9 2.2e-34 117.4 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) IER PF05760.7 EOO01498.1 - 0.089 12.7 2.6 0.094 12.6 1.8 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) COPI_assoc PF08507.5 EOO01499.1 - 2.5e-46 156.8 7.2 2.7e-46 156.6 5.0 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 EOO01499.1 - 0.32 10.0 8.9 0.29 10.2 1.2 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD DUF3784 PF12650.2 EOO01499.1 - 8.7 6.3 12.1 1.8 8.5 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) ATP-synt_C PF00137.16 EOO01500.1 - 2e-28 98.0 24.0 1.3e-17 63.4 4.8 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Cation_efflux PF01545.16 EOO01500.1 - 0.72 8.8 10.3 0.15 11.1 0.2 2.6 1 1 0 2 2 2 0 Cation efflux family DNA_mis_repair PF01119.14 EOO01501.1 - 8.5e-20 70.3 0.0 2.2e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EOO01501.1 - 8.3e-16 57.8 0.1 2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EOO01501.1 - 3.2e-14 52.7 0.5 3.1e-12 46.3 0.0 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EOO01501.1 - 5.2e-12 45.4 0.0 2e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIF_alpha PF05793.7 EOO01501.1 - 0.094 11.0 31.5 0.16 10.3 21.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aldo_ket_red PF00248.16 EOO01502.1 - 5.7e-62 209.1 0.0 6.5e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1279 PF06916.8 EOO01502.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Asp PF00026.18 EOO01503.1 - 3.4e-10 39.6 5.4 7.2e-06 25.4 0.2 3.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EOO01503.1 - 0.0014 18.1 0.1 0.096 12.2 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF3579 PF12112.3 EOO01503.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) DUF3894 PF13033.1 EOO01503.1 - 0.91 9.5 3.6 0.61 10.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) Cohesin_load PF10345.4 EOO01504.1 - 9.3e-118 394.0 0.2 1e-117 393.8 0.2 1.0 1 0 0 1 1 1 1 Cohesin loading factor PfkB PF00294.19 EOO01505.1 - 1.1e-53 182.3 0.8 1.3e-53 182.0 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pyr_redox_2 PF07992.9 EOO01507.1 - 5.5e-08 32.9 0.0 9.6e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO01507.1 - 6.6e-05 23.0 0.3 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EOO01507.1 - 0.00016 20.7 0.2 0.00022 20.2 0.1 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EOO01507.1 - 0.00018 20.5 1.3 0.32 9.8 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EOO01507.1 - 0.00035 20.9 0.3 0.00072 19.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.14 EOO01507.1 - 0.0056 16.3 0.1 0.022 14.4 0.0 2.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain NAD_binding_9 PF13454.1 EOO01507.1 - 0.054 13.2 0.5 6.1 6.5 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EOO01507.1 - 0.091 11.8 0.1 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family IF-2B PF01008.12 EOO01508.1 - 2.2e-39 135.1 0.0 3.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family GARS_N PF02844.10 EOO01508.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain DEDD_Tnp_IS110 PF01548.12 EOO01508.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Transposase MAS20 PF02064.10 EOO01509.1 - 9.3e-16 57.8 0.2 3.3e-15 56.0 0.2 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor DUF466 PF04328.8 EOO01509.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF466) OEP PF02321.13 EOO01509.1 - 0.041 13.4 3.7 0.08 12.5 2.6 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Ctr PF04145.10 EOO01509.1 - 0.064 13.3 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DBINO PF13892.1 EOO01509.1 - 0.092 12.7 6.3 0.14 12.2 4.4 1.2 1 0 0 1 1 1 0 DNA-binding domain DUF3824 PF12868.2 EOO01509.1 - 0.74 10.7 7.3 2.6 9.0 5.1 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Nbs1_C PF08599.5 EOO01509.1 - 1.3 8.9 4.4 0.74 9.7 1.4 1.7 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 SNF2_N PF00176.18 EOO01510.1 - 1.4e-73 247.2 0.0 2.1e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EOO01510.1 - 2e-17 63.0 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EOO01510.1 - 7.3e-11 41.7 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EOO01510.1 - 8.4e-10 38.3 9.6 8.4e-10 38.3 6.7 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EOO01510.1 - 4.6e-09 35.8 10.9 6.8e-09 35.2 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO01510.1 - 1.6e-08 34.3 11.3 1.6e-08 34.3 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO01510.1 - 2.2e-08 33.6 10.9 2.2e-08 33.6 7.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO01510.1 - 5.5e-07 29.2 9.6 1.2e-06 28.1 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EOO01510.1 - 1.8e-06 27.7 9.9 3.7e-06 26.7 6.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EOO01510.1 - 6.3e-05 23.0 6.5 0.00015 21.7 4.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EOO01510.1 - 0.00026 20.7 4.6 0.00064 19.4 3.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DHC_N1 PF08385.7 EOO01510.1 - 0.0028 16.1 0.3 0.0044 15.4 0.2 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Rad50_zn_hook PF04423.9 EOO01510.1 - 0.0034 16.8 1.1 1 8.8 0.1 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Apc11 PF12861.2 EOO01510.1 - 0.0048 16.6 3.5 0.01 15.6 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EOO01510.1 - 0.0049 16.5 7.4 0.0049 16.5 5.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EOO01510.1 - 0.027 14.0 7.8 0.1 12.2 5.5 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EOO01510.1 - 0.3 10.6 4.2 0.69 9.5 2.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.7 EOO01510.1 - 1.3 8.8 6.0 2.6 7.8 4.1 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.9 EOO01510.1 - 1.6 8.2 10.3 0.29 10.6 1.2 2.7 2 1 1 3 3 3 0 P-11 zinc finger DZR PF12773.2 EOO01510.1 - 2.9 7.7 6.1 7.9 6.3 4.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon TFIIA_gamma_C PF02751.9 EOO01512.1 - 2.5e-26 91.2 0.9 3.6e-26 90.7 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EOO01512.1 - 1.3e-25 88.6 0.3 1.9e-25 88.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain FAD_binding_4 PF01565.18 EOO01513.1 - 1.9e-26 92.1 0.5 3.1e-26 91.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EOO01513.1 - 4.2e-05 23.3 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 EOO01513.1 - 0.0056 16.3 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 EOO01513.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Clat_adaptor_s PF01217.15 EOO01514.1 - 1.4e-56 190.1 1.6 1.5e-56 190.0 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FAD_binding_1 PF00667.15 EOO01515.1 - 6.2e-29 101.0 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EOO01515.1 - 7.3e-23 81.1 0.0 1.3e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EOO01515.1 - 6.5e-12 45.9 0.0 1.5e-08 35.1 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EOO01515.1 - 4.8e-05 23.3 0.0 9.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain UCH PF00443.24 EOO01516.1 - 4.7e-28 98.0 0.0 7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EOO01516.1 - 3e-12 46.4 0.1 5.6e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EOO01516.1 - 0.0059 16.0 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3112 PF11309.3 EOO01517.1 - 2.4e-49 167.1 19.2 4.1e-45 153.4 4.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Clr2 PF10383.4 EOO01519.1 - 4e-15 56.0 0.2 6.5e-14 52.1 0.2 2.3 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 DUF3402 PF11882.3 EOO01520.1 - 6.5e-116 387.7 0.0 9.5e-116 387.2 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) AgrD PF05931.6 EOO01520.1 - 0.31 10.6 1.4 0.77 9.4 0.9 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein ETF PF01012.16 EOO01521.1 - 6.9e-41 139.6 0.4 6.9e-41 139.6 0.3 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EOO01521.1 - 2e-36 123.4 0.3 5.5e-36 122.0 0.2 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DnaJ PF00226.26 EOO01522.1 - 4.1e-27 93.6 2.4 6.4e-27 93.0 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EOO01522.1 - 4.5e-21 74.5 2.2 1.9e-18 66.1 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain B56 PF01603.15 EOO01523.1 - 2.6e-175 582.9 4.1 3e-175 582.7 2.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) WD40 PF00400.27 EOO01524.1 - 5.3e-13 48.3 11.9 2.5e-07 30.3 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat HAD_2 PF13419.1 EOO01525.1 - 7.5e-19 68.6 0.0 1e-18 68.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EOO01525.1 - 2.9e-09 36.5 0.2 5.8e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EOO01525.1 - 8e-07 29.6 0.1 3.5e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EOO01525.1 - 0.00011 21.9 0.0 0.0094 15.6 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase UDPG_MGDP_dh_C PF03720.10 EOO01525.1 - 0.011 15.9 0.1 0.065 13.3 0.0 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Asp_Glu_race PF01177.17 EOO01525.1 - 0.042 13.7 0.2 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 Asp/Glu/Hydantoin racemase PAP2 PF01569.16 EOO01526.1 - 3.1e-15 55.9 1.6 3.1e-15 55.9 1.1 2.1 1 1 1 2 2 2 1 PAP2 superfamily Phage_holin_3 PF05106.7 EOO01526.1 - 0.015 15.2 6.8 0.96 9.4 1.5 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DUF212 PF02681.9 EOO01526.1 - 0.023 14.3 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family ATP_bind_1 PF03029.12 EOO01527.1 - 6.5e-68 228.8 0.0 8.9e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Atg14 PF10186.4 EOO01528.1 - 0.52 9.2 9.1 0.61 8.9 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RR_TM4-6 PF06459.7 EOO01528.1 - 7.2 6.4 15.7 11 5.8 10.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zn_clus PF00172.13 EOO01529.1 - 6e-09 35.6 12.5 1.2e-08 34.6 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EOO01529.1 - 0.0014 17.2 0.0 0.002 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Svf1 PF08622.5 EOO01530.1 - 2.9e-121 404.4 0.0 3.6e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EOO01530.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) KH_4 PF13083.1 EOO01530.1 - 0.0042 16.6 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 KH domain MCM PF00493.18 EOO01531.1 - 2.1e-129 431.0 0.4 3.2e-129 430.4 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EOO01531.1 - 3.9e-17 62.8 0.1 2.2e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EOO01531.1 - 2.9e-07 29.8 0.0 3.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EOO01531.1 - 0.0048 16.5 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EOO01531.1 - 0.014 14.8 0.0 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Fungal_trans_2 PF11951.3 EOO01532.1 - 0.00021 20.0 0.0 0.00033 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 EOO01533.1 - 2e-59 200.2 0.1 2.6e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EOO01533.1 - 5.2e-26 90.7 0.0 3.3e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EOO01533.1 - 1.2e-16 60.5 3.4 1.2e-16 60.5 2.4 2.1 2 1 1 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EOO01533.1 - 3.6e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EOO01533.1 - 0.00017 21.1 0.5 0.00042 19.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EOO01533.1 - 0.0026 18.2 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EOO01533.1 - 0.086 12.3 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EOO01534.1 - 1.8e-38 131.7 0.0 3.2e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO01534.1 - 2.6e-06 27.6 0.4 0.001 19.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EOO01534.1 - 2.7e-06 27.5 0.7 0.00012 22.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EOO01534.1 - 7.2e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EOO01534.1 - 1.8e-05 23.9 0.0 3.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EOO01534.1 - 3.3e-05 23.6 0.1 0.00027 20.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EOO01534.1 - 3.5e-05 24.6 0.0 0.0001 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EOO01534.1 - 4.6e-05 23.3 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EOO01534.1 - 0.00069 18.7 0.2 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EOO01534.1 - 0.00072 19.4 0.0 0.0023 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EOO01534.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EOO01534.1 - 0.0011 19.0 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EOO01534.1 - 0.0011 18.1 0.1 0.0032 16.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EOO01534.1 - 0.0021 17.7 0.2 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EOO01534.1 - 0.003 17.7 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.7 EOO01534.1 - 0.0046 16.6 0.0 0.014 15.0 0.0 1.9 1 1 1 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 EOO01534.1 - 0.0072 15.8 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EOO01534.1 - 0.012 14.9 2.3 0.1 11.9 0.1 2.7 2 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EOO01534.1 - 0.014 15.4 0.1 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EOO01534.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EOO01534.1 - 0.019 13.8 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EOO01534.1 - 0.022 13.6 0.0 0.06 12.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Oxidored_nitro PF00148.14 EOO01534.1 - 0.024 13.2 0.0 0.18 10.4 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Arch_ATPase PF01637.13 EOO01534.1 - 0.032 13.9 0.0 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 EOO01534.1 - 0.06 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EOO01534.1 - 0.06 12.0 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 EOO01534.1 - 0.066 12.9 0.1 13 5.4 0.0 2.9 3 0 0 3 3 3 0 NTPase Phage_GP20 PF06810.6 EOO01534.1 - 0.066 12.6 0.8 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 ABC_tran PF00005.22 EOO01534.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.13 EOO01534.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EOO01534.1 - 0.076 13.3 2.8 0.095 13.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 EOO01534.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EOO01534.1 - 0.099 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EOO01534.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein tRNA-synt_1g PF09334.6 EOO01535.1 - 7.2e-132 439.7 0.2 4e-129 430.6 0.2 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EOO01535.1 - 1.5e-05 23.2 2.9 0.0029 15.6 0.0 2.9 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EOO01535.1 - 0.00022 21.0 0.3 0.00084 19.1 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF1682 PF07946.9 EOO01535.1 - 0.22 10.3 7.7 0.36 9.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) K_channel_TID PF07941.6 EOO01535.1 - 0.32 11.2 5.1 0.65 10.2 3.6 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SR-25 PF10500.4 EOO01535.1 - 1.1 8.7 12.6 1.7 8.0 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDO_I PF05995.7 EOO01536.1 - 0.0009 18.4 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I Methyltransf_33 PF10017.4 EOO01537.1 - 1.5e-30 105.7 0.0 2.7e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EOO01537.1 - 2.2e-20 73.0 0.3 2.6e-19 69.6 0.2 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EOO01537.1 - 0.004 17.4 0.1 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily SAP PF02037.22 EOO01538.1 - 2.8e-13 49.0 0.4 5.8e-13 47.9 0.3 1.6 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 EOO01538.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_P_Rpp14 PF01900.14 EOO01539.1 - 5e-38 129.3 0.0 6.5e-38 128.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Tim17 PF02466.14 EOO01540.1 - 1.7e-48 163.8 11.7 2e-48 163.6 8.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EOO01540.1 - 0.018 14.9 0.1 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) NDUF_B12 PF08122.7 EOO01540.1 - 1.7 8.4 4.1 11 5.8 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Glyco_hydro_16 PF00722.16 EOO01541.1 - 5.7e-12 45.2 0.8 1.2e-11 44.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 GP41 PF00517.12 EOO01541.1 - 0.0074 15.8 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Retroviral envelope protein Wzy_C PF04932.10 EOO01541.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase ASFV_J13L PF05568.6 EOO01541.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Synaptobrevin PF00957.16 EOO01541.1 - 0.039 13.5 0.2 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 Synaptobrevin Sensor PF13796.1 EOO01541.1 - 0.058 12.9 0.2 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative sensor DUF2142 PF09913.4 EOO01541.1 - 0.058 12.0 0.9 0.11 11.1 0.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2771 PF10969.3 EOO01541.1 - 0.061 12.5 0.4 0.49 9.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) RELT PF12606.3 EOO01541.1 - 0.29 10.3 4.1 0.49 9.5 2.9 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF4307 PF14155.1 EOO01541.1 - 0.33 10.7 3.6 0.15 11.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) VirB8 PF04335.8 EOO01541.1 - 1.6 8.2 8.0 1.1 8.7 1.6 2.1 1 1 1 2 2 2 0 VirB8 protein WD40 PF00400.27 EOO01542.1 - 8.2e-21 73.0 0.1 2.2e-06 27.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF917 PF06032.7 EOO01543.1 - 3.6e-106 354.6 0.1 7.9e-106 353.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EOO01543.1 - 6.2e-48 163.3 4.6 6.2e-48 163.3 3.2 2.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO01543.1 - 1.6e-18 66.8 0.3 3.7e-16 59.1 0.2 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EOO01543.1 - 0.00029 19.8 0.8 0.065 12.1 0.1 2.5 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.15 EOO01543.1 - 0.0012 18.1 3.1 0.11 11.7 0.8 3.1 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MerR-DNA-bind PF09278.6 EOO01544.1 - 0.035 14.4 0.0 0.069 13.5 0.0 1.5 2 0 0 2 2 2 0 MerR, DNA binding Abhydrolase_3 PF07859.8 EOO01545.1 - 3.3e-16 59.4 0.5 8.8e-14 51.5 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EOO01545.1 - 1.1e-10 40.7 0.1 1.7e-09 36.8 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EOO01545.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family OTU PF02338.14 EOO01549.1 - 1.7e-12 48.0 0.0 3.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.15 EOO01549.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 UBX domain Lipase_GDSL_2 PF13472.1 EOO01550.1 - 2.7e-08 34.1 0.0 3.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO01550.1 - 0.0002 21.2 0.1 0.00042 20.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EOO01550.1 - 0.015 15.0 0.3 0.057 13.1 0.2 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_tranf_2_5 PF13712.1 EOO01550.1 - 0.069 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family MFS_1 PF07690.11 EOO01551.1 - 8.2e-28 97.1 25.2 8.2e-28 97.1 17.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.8 EOO01552.1 - 2.3e-14 53.2 0.0 3.5e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01552.1 - 4.8e-13 49.5 0.1 7.2e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EOO01552.1 - 4.5e-07 29.1 0.1 7.8e-07 28.4 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EOO01552.1 - 0.00018 21.0 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EOO01552.1 - 0.00058 19.7 0.1 0.0015 18.4 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EOO01552.1 - 0.00096 19.0 0.4 0.002 18.0 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 EOO01552.1 - 0.0014 18.4 0.2 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EOO01552.1 - 0.0019 18.5 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EOO01552.1 - 0.004 15.8 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EOO01552.1 - 0.0095 16.2 0.1 0.026 14.8 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EOO01552.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.13 EOO01552.1 - 0.024 14.6 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EOO01552.1 - 0.085 13.3 0.1 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 EOO01552.1 - 0.13 12.4 0.1 4.8 7.3 0.1 2.4 1 1 0 1 1 1 0 CoA binding domain MFS_1 PF07690.11 EOO01553.1 - 2.7e-09 36.2 10.2 4.4e-09 35.5 7.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3112 PF11309.3 EOO01553.1 - 0.011 15.4 1.9 0.026 14.2 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) SP_C-Propep PF08999.5 EOO01553.1 - 1.1 8.7 3.6 0.5 9.8 0.3 2.1 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide WSC PF01822.14 EOO01554.1 - 1.3e-13 50.6 12.5 3.7e-13 49.1 8.6 1.8 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EOO01554.1 - 6.1e-09 35.0 1.1 1.5e-08 33.8 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EOO01554.1 - 0.00049 19.7 1.9 0.00093 18.7 1.3 1.4 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.1 EOO01554.1 - 0.00083 18.8 0.5 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF4448 PF14610.1 EOO01554.1 - 0.00083 18.8 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1191 PF06697.7 EOO01554.1 - 0.0074 15.1 0.2 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Glycophorin_A PF01102.13 EOO01554.1 - 0.011 15.4 0.5 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 Glycophorin A Trp_oprn_chp PF09534.5 EOO01554.1 - 0.013 15.0 0.8 0.021 14.4 0.5 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rax2 PF12768.2 EOO01554.1 - 0.043 13.0 0.2 0.063 12.4 0.2 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EOO01554.1 - 0.044 14.1 1.0 0.46 10.9 0.0 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sel1 PF08238.7 EOO01555.1 - 3.2e-11 43.4 34.3 0.00016 22.1 0.1 7.4 7 0 0 7 7 7 3 Sel1 repeat TPR_1 PF00515.23 EOO01555.1 - 0.002 17.6 0.4 0.002 17.6 0.3 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EOO01555.1 - 0.03 14.2 0.3 0.03 14.2 0.2 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EOO01555.1 - 0.061 14.0 0.2 0.061 14.0 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EOO01555.1 - 0.082 12.7 0.1 0.34 10.7 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EOO01555.1 - 0.16 11.6 9.0 0.11 12.2 0.4 3.2 3 1 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 EOO01555.1 - 0.18 11.6 3.0 0.2 11.5 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EOO01555.1 - 0.36 11.3 0.1 0.36 11.3 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO01555.1 - 0.43 11.3 8.9 1.3 9.8 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EOO01556.1 - 6.4e-149 496.5 0.0 1e-148 495.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EOO01556.1 - 2.4e-85 286.6 0.0 3.2e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EOO01556.1 - 7e-51 168.3 12.8 2.4e-09 36.7 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Clathrin PF00637.15 EOO01556.1 - 0.036 13.6 0.3 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.3 EOO01556.1 - 0.15 10.1 8.7 0.28 9.2 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Bromodomain PF00439.20 EOO01558.1 - 1.7e-38 130.4 1.2 2.4e-20 72.2 0.5 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EOO01558.1 - 2.4e-19 69.2 1.7 8.6e-19 67.4 1.2 2.0 1 0 0 1 1 1 1 BAH domain AAT PF03417.11 EOO01559.1 - 6.5e-07 29.0 0.1 1.6e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MFS_1 PF07690.11 EOO01560.1 - 1.2e-39 136.0 48.0 1.2e-39 136.0 33.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO01560.1 - 1.2e-16 60.0 26.5 2.4e-16 59.0 18.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M43 PF05572.8 EOO01561.1 - 7.3e-13 48.3 0.1 1.4e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EOO01561.1 - 7.6e-06 25.9 0.4 1.6e-05 24.9 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EOO01561.1 - 0.00019 21.5 1.2 0.00032 20.8 0.7 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EOO01561.1 - 0.00081 19.9 0.7 0.006 17.1 0.2 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EOO01561.1 - 0.014 14.9 0.2 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NYN PF01936.13 EOO01562.1 - 0.023 15.0 0.0 0.069 13.4 0.0 1.9 1 1 0 1 1 1 0 NYN domain EI24 PF07264.6 EOO01563.1 - 1.5e-08 34.3 11.7 5.4e-07 29.2 8.1 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.10 EOO01564.1 - 1.2e-139 465.0 0.0 1.5e-139 464.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family HEAT PF02985.17 EOO01565.1 - 1.7e-18 64.9 10.0 0.0012 18.7 0.0 8.9 9 0 0 9 9 8 5 HEAT repeat HEAT_2 PF13646.1 EOO01565.1 - 2.3e-18 66.2 11.4 4.6e-10 39.6 0.1 8.0 6 2 2 8 8 5 4 HEAT repeats HEAT_EZ PF13513.1 EOO01565.1 - 1.1e-14 54.3 15.5 0.00011 22.5 0.0 10.3 8 2 3 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EOO01565.1 - 1.6e-10 41.2 1.2 0.0017 18.7 0.0 7.6 7 2 4 11 11 9 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EOO01565.1 - 6e-09 35.7 0.0 0.00011 21.9 0.0 4.6 2 2 2 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EOO01565.1 - 8.5e-09 34.6 0.5 3e-05 22.9 0.1 3.4 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EOO01565.1 - 5e-08 32.5 0.3 0.0023 17.3 0.0 5.7 6 1 1 7 7 7 1 CLASP N terminal Cnd1 PF12717.2 EOO01565.1 - 0.00012 21.9 0.8 1.4 8.6 0.0 5.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EOO01565.1 - 0.00016 20.1 0.0 0.0012 17.1 0.0 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit CAS_CSE1 PF03378.10 EOO01565.1 - 0.00038 18.8 0.1 1 7.5 0.0 3.3 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus Adaptin_N PF01602.15 EOO01565.1 - 0.00053 18.4 1.8 0.061 11.6 0.3 3.5 2 1 2 4 4 4 2 Adaptin N terminal region TFCD_C PF12612.3 EOO01565.1 - 0.0021 17.5 0.2 0.29 10.5 0.0 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Arm PF00514.18 EOO01565.1 - 0.0035 17.1 8.7 0.89 9.4 0.1 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EOO01565.1 - 0.0068 15.5 5.3 0.66 9.0 0.0 3.7 3 1 0 3 3 3 1 V-ATPase subunit H TAN PF11640.3 EOO01565.1 - 0.0085 15.8 0.4 0.04 13.6 0.1 2.4 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Telomere_reg-2 PF10193.4 EOO01565.1 - 0.017 15.4 0.6 0.017 15.4 0.4 2.7 4 0 0 4 4 2 0 Telomere length regulation protein DUF3535 PF12054.3 EOO01565.1 - 0.025 13.1 0.1 0.053 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) HrcA_DNA-bdg PF03444.10 EOO01565.1 - 0.037 13.4 1.5 47 3.5 0.0 3.8 4 0 0 4 4 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Xpo1 PF08389.7 EOO01565.1 - 0.057 13.3 0.1 8.5 6.2 0.0 3.8 3 0 0 3 3 3 0 Exportin 1-like protein FdhE PF04216.7 EOO01565.1 - 0.061 13.0 4.3 0.11 12.2 0.1 3.1 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation DUF4042 PF13251.1 EOO01565.1 - 0.073 12.5 0.0 6.6 6.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) IBN_N PF03810.14 EOO01565.1 - 0.084 12.8 0.0 0.75 9.7 0.0 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain Apolipoprotein PF01442.13 EOO01565.1 - 0.4 10.1 5.4 11 5.4 0.2 3.6 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain Ammonium_transp PF00909.16 EOO01566.1 - 2.2e-112 375.4 20.9 2.5e-112 375.2 14.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ax_dynein_light PF10211.4 EOO01567.1 - 0.00019 21.3 8.4 0.00019 21.3 5.8 2.4 2 1 1 3 3 3 1 Axonemal dynein light chain Mito_fiss_reg PF05308.6 EOO01567.1 - 0.00089 18.6 6.5 0.00089 18.6 4.5 1.5 2 0 0 2 2 2 1 Mitochondrial fission regulator CENP-F_leu_zip PF10473.4 EOO01567.1 - 0.0011 18.8 5.0 0.0011 18.8 3.4 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GOLGA2L5 PF15070.1 EOO01567.1 - 0.0043 15.6 10.0 0.0043 15.6 7.0 2.0 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Baculo_PEP_C PF04513.7 EOO01567.1 - 0.006 16.4 6.3 0.036 13.9 1.0 2.6 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EOO01567.1 - 0.0064 16.3 23.5 0.084 12.7 6.1 3.0 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 EOO01567.1 - 0.025 11.9 20.7 0.04 11.2 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 EOO01567.1 - 0.028 14.1 0.3 0.028 14.1 0.2 4.4 5 0 0 5 5 4 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EOO01567.1 - 0.03 13.4 3.1 0.31 10.1 0.4 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EOO01567.1 - 0.043 13.9 13.8 0.52 10.4 2.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EOO01567.1 - 0.088 11.9 27.4 0.28 10.3 4.2 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CortBP2 PF09727.4 EOO01567.1 - 0.12 11.8 20.3 0.057 12.9 7.2 2.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 IncA PF04156.9 EOO01567.1 - 0.14 11.7 26.5 0.55 9.8 10.9 2.3 1 1 1 2 2 2 0 IncA protein SPX PF03105.14 EOO01567.1 - 0.15 11.8 18.7 1.4 8.6 11.9 2.0 1 1 1 2 2 2 0 SPX domain Filament PF00038.16 EOO01567.1 - 0.17 11.3 24.4 0.14 11.5 5.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein IFT57 PF10498.4 EOO01567.1 - 0.25 10.0 20.0 1.2 7.7 6.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Striatin PF08232.7 EOO01567.1 - 0.43 10.8 19.2 2.3 8.5 5.4 2.3 1 1 1 2 2 2 0 Striatin family YlqD PF11068.3 EOO01567.1 - 0.45 10.5 18.8 0.62 10.0 3.8 2.2 1 1 1 2 2 2 0 YlqD protein DUF3450 PF11932.3 EOO01567.1 - 0.51 9.5 18.5 0.13 11.5 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF919 PF06034.6 EOO01567.1 - 0.59 9.7 0.1 0.59 9.7 0.0 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CDC37_N PF03234.9 EOO01567.1 - 0.75 10.0 16.4 1.1 9.5 11.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding MUG113 PF13455.1 EOO01567.1 - 0.87 10.0 6.0 0.48 10.9 0.5 2.3 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Atg14 PF10186.4 EOO01567.1 - 0.9 8.4 17.3 1.4 7.7 12.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EOO01567.1 - 0.91 7.8 19.0 1.2 7.5 13.2 1.1 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EOO01567.1 - 1.2 8.9 25.6 0.38 10.4 10.4 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EOO01567.1 - 1.2 9.1 22.3 1.2 9.1 1.8 4.6 1 1 4 5 5 5 0 bZIP transcription factor Cut12 PF11500.3 EOO01567.1 - 1.4 8.5 14.8 1.1 8.8 3.1 2.4 1 1 0 2 2 2 0 Spindle pole body formation-associated protein DUF1311 PF07007.7 EOO01567.1 - 1.5 8.9 12.2 3.1e+02 1.5 8.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1311) APG6 PF04111.7 EOO01567.1 - 1.7 7.6 28.8 1.1 8.1 7.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EOO01567.1 - 1.8 8.2 24.0 3 7.4 5.5 2.3 1 1 1 2 2 2 0 Mnd1 family DUF2968 PF11180.3 EOO01567.1 - 2.1 7.6 16.5 0.42 9.9 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) OmpH PF03938.9 EOO01567.1 - 2.2 8.1 21.6 2.4e+02 1.5 15.0 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 EOO01567.1 - 2.3 8.6 21.1 0.7 10.2 3.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EOO01567.1 - 2.3 7.7 26.7 0.77 9.2 2.0 4.7 1 1 3 5 5 5 0 Septum formation initiator GrpE PF01025.14 EOO01567.1 - 3.5 7.1 25.8 0.98 8.9 3.6 3.0 1 1 1 2 2 2 0 GrpE CTNNB1_binding PF08347.6 EOO01567.1 - 3.7 7.7 12.8 5.5 7.1 7.4 2.1 1 1 1 2 2 2 0 N-terminal CTNNB1 binding TBPIP PF07106.8 EOO01567.1 - 3.9 6.9 22.5 1.7 8.1 5.1 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cauli_DNA-bind PF03310.8 EOO01567.1 - 4.7 7.0 8.3 1.6 8.6 3.1 1.9 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein UPF0242 PF06785.6 EOO01567.1 - 5.8 5.4 13.1 7.8 5.0 9.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4407 PF14362.1 EOO01567.1 - 6.6 5.5 19.8 50 2.7 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF904 PF06005.7 EOO01567.1 - 7.3 6.9 24.5 27 5.1 2.0 3.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 EOO01567.1 - 7.5 6.2 26.4 4.4 7.0 9.8 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 EOO01567.1 - 8.5 6.0 13.7 4.5 6.9 4.2 2.3 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 bZIP_2 PF07716.10 EOO01567.1 - 8.9 6.2 26.0 12 5.8 1.9 4.9 2 2 3 5 5 5 0 Basic region leucine zipper adh_short PF00106.20 EOO01569.1 - 6.7e-19 68.4 0.2 8.2e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01569.1 - 2e-12 47.1 0.5 2.7e-12 46.7 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO01569.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CRCB PF02537.10 EOO01569.1 - 0.1 12.5 0.1 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 CrcB-like protein Shikimate_DH PF01488.15 EOO01569.1 - 0.2 11.7 0.9 0.36 10.9 0.5 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_11 PF00457.12 EOO01570.1 - 8.9e-78 259.8 22.6 1e-77 259.6 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SAC3_GANP PF03399.11 EOO01571.1 - 1.1e-25 90.4 0.0 1.5e-25 89.9 0.0 1.3 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EOO01571.1 - 1.9e-20 73.1 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 GPI-anchored PF10342.4 EOO01572.1 - 4.5e-07 30.2 0.0 6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UDP-g_GGTase PF06427.6 EOO01574.1 - 3.2e-63 212.8 0.0 5.9e-62 208.7 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EOO01574.1 - 0.00092 18.6 1.0 0.0028 17.0 0.7 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Cofilin_ADF PF00241.15 EOO01575.1 - 1.1e-17 64.0 0.1 1.2e-17 63.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SNF2_N PF00176.18 EOO01576.1 - 2.1e-69 233.5 0.0 3.4e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EOO01576.1 - 6.6e-64 215.3 6.1 2.5e-63 213.4 3.8 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EOO01576.1 - 4.7e-13 48.8 0.0 1.7e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EOO01576.1 - 3.8e-05 22.6 0.1 0.00013 20.8 0.0 1.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EOO01576.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Citrate_ly_lig PF08218.6 EOO01576.1 - 0.01 15.3 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain AAA_22 PF13401.1 EOO01576.1 - 0.12 12.5 0.1 1.5 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain CBS PF00571.23 EOO01577.1 - 1e-18 66.8 1.4 1.9e-06 27.5 0.1 4.5 4 0 0 4 4 4 4 CBS domain Pectinesterase PF01095.14 EOO01578.1 - 3.1e-42 144.1 7.6 3.1e-42 144.1 5.3 2.4 2 0 0 2 2 2 1 Pectinesterase DUF1975 PF09318.5 EOO01578.1 - 0.021 14.4 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) Gcd10p PF04189.8 EOO01579.1 - 8.8e-66 222.0 0.0 1.8e-65 221.0 0.0 1.5 1 1 0 1 1 1 1 Gcd10p family Pyr_redox_2 PF07992.9 EOO01581.1 - 5.4e-13 49.2 2.5 2.5e-05 24.2 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO01581.1 - 2.6e-12 46.9 1.1 4e-09 36.7 0.4 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO01581.1 - 3.1e-06 27.3 0.4 0.27 11.2 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO01581.1 - 0.00019 20.4 8.4 0.021 13.7 0.2 3.8 2 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EOO01581.1 - 0.015 15.0 6.0 3.9 7.2 0.0 3.9 4 1 1 5 5 5 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EOO01581.1 - 0.019 13.6 3.9 1.6 7.2 0.0 2.6 2 1 1 3 3 3 0 Tryptophan halogenase Abhydrolase_6 PF12697.2 EOO01581.1 - 0.034 14.0 0.0 0.098 12.5 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family K_oxygenase PF13434.1 EOO01581.1 - 0.048 12.5 0.0 0.16 10.8 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_S9 PF00326.16 EOO01581.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family GIDA PF01134.17 EOO01581.1 - 0.11 11.3 3.5 0.96 8.2 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF4066 PF13278.1 EOO01584.1 - 7.5e-11 41.5 0.0 8.7e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EOO01584.1 - 1.8e-07 30.6 0.0 2.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_3_C PF01915.17 EOO01585.1 - 7e-64 215.4 0.2 1e-62 211.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EOO01585.1 - 1.1e-47 162.4 0.0 1.6e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EOO01585.1 - 1.7e-20 72.7 0.2 4.5e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EOO01585.1 - 4.8e-06 26.2 0.0 9.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Exo_endo_phos PF03372.18 EOO01586.1 - 9.2e-10 38.8 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myosin_N PF02736.14 EOO01586.1 - 0.1 12.3 0.8 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain P21-Arc PF04062.9 EOO01588.1 - 9.8e-48 162.2 0.0 1.1e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NmrA PF05368.8 EOO01589.1 - 2.8e-22 79.1 0.0 4.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01589.1 - 5.4e-14 52.6 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EOO01589.1 - 0.013 14.5 0.5 0.021 13.8 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EOO01589.1 - 0.02 14.3 0.5 0.056 12.8 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1003 PF06210.6 EOO01589.1 - 0.024 14.5 0.4 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) 3Beta_HSD PF01073.14 EOO01589.1 - 0.089 11.4 1.4 0.12 11.0 0.1 1.9 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EOO01589.1 - 0.11 12.4 3.7 0.063 13.1 0.8 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DUF2758 PF10957.3 EOO01589.1 - 0.22 11.3 1.0 0.44 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) Tyrosinase PF00264.15 EOO01590.1 - 1.7e-23 83.9 1.4 2.3e-23 83.5 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase AIRS PF00586.19 EOO01590.1 - 0.0052 16.9 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GF_recep_IV PF14843.1 EOO01590.1 - 0.031 13.8 0.1 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV Paf67 PF10255.4 EOO01591.1 - 1.8e-153 511.2 0.6 2.1e-153 510.9 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EOO01591.1 - 0.023 14.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EOO01591.1 - 0.063 12.9 0.1 0.81 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat End_beta_barrel PF12195.3 EOO01591.1 - 0.075 12.7 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase TPR_12 PF13424.1 EOO01591.1 - 0.12 12.3 0.8 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 EOO01592.1 - 4.7e-27 95.3 0.0 5.7e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO01592.1 - 1.8e-22 80.0 0.1 2.4e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01592.1 - 1.7e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 KR domain TIM-br_sig_trns PF09370.5 EOO01592.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein NAD_binding_4 PF07993.7 EOO01592.1 - 0.079 11.8 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Usp PF00582.21 EOO01593.1 - 5.1e-14 52.6 0.4 1.9e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Protocadherin PF08374.6 EOO01593.1 - 0.15 11.7 2.2 0.3 10.6 1.5 1.6 1 1 0 1 1 1 0 Protocadherin DUF834 PF05754.9 EOO01593.1 - 1.1 9.1 7.8 0.35 10.6 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF834) HeLo PF14479.1 EOO01594.1 - 8e-43 146.6 0.1 1.1e-42 146.2 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 EOO01594.1 - 6.3e-15 54.8 0.4 1.4e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 Het-s 218-289 DUF4572 PF15139.1 EOO01594.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) Ank_2 PF12796.2 EOO01595.1 - 6e-39 132.2 0.5 6.5e-14 52.0 0.0 5.5 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EOO01595.1 - 1.2e-28 98.9 3.0 2.2e-08 34.4 0.0 7.5 4 1 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO01595.1 - 1e-25 87.2 0.3 1.3e-06 28.0 0.0 9.6 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.25 EOO01595.1 - 7.5e-25 85.4 6.1 3.9e-08 32.7 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EOO01595.1 - 1.1e-20 73.1 5.9 4.2e-11 42.7 0.1 7.6 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Fe-ADH PF00465.14 EOO01596.1 - 3.1e-100 335.3 1.4 5.7e-100 334.4 0.1 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.17 EOO01596.1 - 5.7e-24 84.2 9.0 3.9e-23 81.5 6.2 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.1 EOO01596.1 - 6.3e-17 61.6 1.1 4.4e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fmp27 PF10344.4 EOO01598.1 - 3.9e-247 822.2 0.0 7e-247 821.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EOO01598.1 - 4.5e-173 576.3 0.1 4.5e-173 576.3 0.1 2.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EOO01598.1 - 1.2e-157 525.1 0.1 1.2e-157 525.1 0.1 1.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EOO01598.1 - 4.8e-53 179.2 0.0 1.2e-52 177.9 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EOO01598.1 - 6.4e-51 172.2 0.5 1.6e-50 170.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EOO01598.1 - 8.6e-35 119.2 0.1 5.6e-34 116.6 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain MFS_1 PF07690.11 EOO01599.1 - 1e-06 27.7 5.8 1e-06 27.7 4.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Aa_trans PF01490.13 EOO01599.1 - 0.0072 14.8 1.1 0.0073 14.8 0.2 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein PEX11 PF05648.9 EOO01600.1 - 3.8e-05 23.0 2.1 0.018 14.3 0.0 2.7 3 0 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Oxidored_FMN PF00724.15 EOO01601.1 - 2e-88 296.6 0.0 2.4e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Flu_B_M2 PF04772.7 EOO01601.1 - 0.0082 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Influenza B matrix protein 2 (BM2) DJ-1_PfpI PF01965.19 EOO01602.1 - 1.3e-16 60.4 0.0 2.6e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EOO01602.1 - 1.5e-05 24.4 0.0 4.4e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family RRM_1 PF00076.17 EOO01603.1 - 5.5e-13 48.3 0.0 9.9e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO01603.1 - 6e-12 45.3 0.0 9.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO01603.1 - 2.5e-05 24.0 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 EOO01603.1 - 4.3 7.1 19.5 7 6.4 13.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NACHT PF05729.7 EOO01604.1 - 1.7e-10 40.7 0.0 2.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EOO01604.1 - 4.7e-05 23.5 0.0 9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO01604.1 - 8.8e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 EOO01604.1 - 0.0042 16.2 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EOO01604.1 - 0.0086 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EOO01604.1 - 0.0092 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EOO01604.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 EOO01604.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EOO01604.1 - 0.015 14.3 0.1 2.9 6.7 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 EOO01604.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EOO01604.1 - 0.052 13.4 0.0 0.75 9.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EOO01604.1 - 0.077 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EOO01604.1 - 0.089 13.0 0.2 0.34 11.2 0.0 2.2 3 1 0 3 3 2 0 AAA domain AAA_10 PF12846.2 EOO01604.1 - 0.09 12.1 0.0 0.39 10.1 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain cobW PF02492.14 EOO01604.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EOO01604.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 NTPase Ag332 PF04671.7 EOO01604.1 - 0.28 11.0 1.3 0.53 10.1 0.9 1.5 1 0 0 1 1 1 0 Erythrocyte membrane-associated giant protein antigen 332 F-box PF00646.28 EOO01605.1 - 2.2e-07 30.3 2.5 4e-07 29.5 1.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EOO01605.1 - 7.8e-06 25.5 1.7 1.7e-05 24.4 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EOO01605.1 - 0.00053 19.6 0.0 0.00091 18.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain Glyco_transf_4 PF13439.1 EOO01606.1 - 0.045 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Alpha-2-MRAP_N PF06400.6 EOO01606.1 - 0.1 12.3 1.7 0.5 10.0 0.1 2.6 1 1 2 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain ABA_GPCR PF12430.3 EOO01607.1 - 2e-51 173.9 0.1 3.5e-51 173.1 0.1 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EOO01607.1 - 9.5e-19 67.2 0.5 9.6e-18 63.9 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) NYN PF01936.13 EOO01608.1 - 4.1e-32 111.4 0.0 8.2e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 EOO01608.1 - 1.4e-18 66.4 0.0 3.1e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Arginase PF00491.16 EOO01608.1 - 3.4e-08 33.1 0.0 5.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Arginase family Agro_virD5 PF04730.7 EOO01608.1 - 0.12 10.3 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Tetrabrachion PF11401.3 EOO01609.1 - 0.015 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetrabrachion Amidohydro_3 PF07969.6 EOO01610.1 - 1.2e-51 176.2 0.7 1.4e-51 175.9 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EOO01610.1 - 5.6e-10 38.9 0.1 3.4e-09 36.3 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 EOO01610.1 - 5.4e-09 36.1 1.0 7.6e-07 29.0 0.7 3.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EOO01610.1 - 2.4e-06 27.7 1.2 0.01 15.8 0.0 2.9 3 1 0 3 3 3 2 Amidohydrolase RE_XcyI PF09571.5 EOO01610.1 - 0.16 10.8 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease Oxidored_FMN PF00724.15 EOO01611.1 - 5.3e-93 311.7 0.0 6.1e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GTP_EFTU PF00009.22 EOO01612.1 - 5.5e-54 182.4 0.0 9.7e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EOO01612.1 - 3.2e-16 58.9 0.0 1e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EOO01612.1 - 2.5e-08 33.9 0.0 6.5e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EOO01612.1 - 1.3e-06 28.1 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EOO01612.1 - 0.0001 21.8 0.0 0.012 15.1 0.0 2.9 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EOO01612.1 - 0.0079 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase UBX PF00789.15 EOO01613.1 - 2.5e-11 43.4 0.0 4.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF2763 PF10961.3 EOO01613.1 - 0.014 15.7 0.1 0.014 15.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) BTV_NS2 PF04514.7 EOO01613.1 - 0.049 12.5 7.3 0.084 11.7 5.1 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF21 PF01595.15 EOO01613.1 - 0.078 12.2 0.1 0.24 10.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF21 CAF-1_p150 PF11600.3 EOO01613.1 - 0.52 9.6 23.9 1.1 8.6 16.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal VSG_B PF13206.1 EOO01613.1 - 1.2 8.2 11.8 1.9 7.5 8.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain PCI PF01399.22 EOO01614.1 - 1.6e-19 70.1 0.1 4.3e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EOO01614.1 - 1.8e-06 27.7 0.3 7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EOO01614.1 - 0.00099 18.7 1.4 0.28 11.0 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO01614.1 - 0.027 14.0 1.3 0.28 10.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EOO01614.1 - 0.048 12.7 0.1 0.65 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_2 PF07719.12 EOO01614.1 - 0.049 13.5 6.3 0.17 11.8 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EOO01614.1 - 0.06 13.3 0.8 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EOO01614.1 - 0.11 12.4 8.3 0.17 11.8 0.2 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EOO01614.1 - 0.22 11.3 3.3 0.45 10.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EOO01614.1 - 5.6 6.6 7.4 0.58 9.8 0.1 3.0 5 0 0 5 5 5 0 TPR repeat Gp5_OB PF06714.6 EOO01616.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Gp5 N-terminal OB domain FAD-oxidase_C PF02913.14 EOO01618.1 - 6.9e-58 195.8 0.0 8.5e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EOO01618.1 - 3.5e-18 65.4 0.0 7.4e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Cu-oxidase_3 PF07732.10 EOO01619.1 - 9.1e-47 157.6 8.5 5.9e-44 148.5 0.6 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EOO01619.1 - 8.9e-34 115.9 14.4 1.2e-33 115.5 2.6 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EOO01619.1 - 3e-29 101.9 0.0 9e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EOO01619.1 - 0.099 12.5 0.0 5.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Cupredoxin-like domain AhpC-TSA_2 PF13911.1 EOO01620.1 - 1.6e-14 53.7 0.2 3.7e-14 52.6 0.2 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EOO01620.1 - 4.1e-06 26.4 0.0 9.1e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EOO01620.1 - 2.9e-05 23.6 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin SMN PF06003.7 EOO01620.1 - 1.3 8.0 6.1 2.6 7.0 4.2 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) EGF_2 PF07974.8 EOO01621.1 - 0.048 13.8 9.6 0.12 12.5 6.7 1.7 1 1 0 1 1 1 0 EGF-like domain Ribosomal_L24e PF01246.15 EOO01622.1 - 6.5e-31 106.0 0.3 6.5e-31 106.0 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e PTS_IIA PF02255.11 EOO01622.1 - 3.1 7.7 6.6 5.2 7.0 4.5 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Methyltransf_2 PF00891.13 EOO01623.1 - 1.5e-31 109.4 0.0 2.5e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EOO01623.1 - 1e-05 26.0 0.0 3.4e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01623.1 - 0.033 13.7 0.0 0.09 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 EOO01623.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MPC PF03650.8 EOO01624.1 - 6.4e-42 142.2 1.1 9.9e-42 141.6 0.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CBP4 PF07960.6 EOO01625.1 - 2.4e-37 127.4 0.6 3.4e-37 126.9 0.4 1.2 1 0 0 1 1 1 1 CBP4 ERCC4 PF02732.10 EOO01625.1 - 0.005 16.5 0.5 0.0059 16.3 0.4 1.1 1 0 0 1 1 1 1 ERCC4 domain FANCF PF11107.3 EOO01625.1 - 0.0063 15.7 0.0 0.0076 15.5 0.0 1.0 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) AAA_11 PF13086.1 EOO01625.1 - 0.03 13.8 0.5 0.034 13.7 0.3 1.0 1 0 0 1 1 1 0 AAA domain DUF2852 PF11014.3 EOO01625.1 - 0.43 10.5 3.2 0.36 10.7 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) SET PF00856.23 EOO01626.1 - 3.9e-16 59.7 0.0 6.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 SET domain Redoxin PF08534.5 EOO01627.1 - 4.8e-34 117.0 0.3 5.4e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EOO01627.1 - 8.8e-13 48.0 0.1 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ras PF00071.17 EOO01629.1 - 4.3e-52 175.7 0.0 5.4e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO01629.1 - 1.2e-19 70.9 0.0 4.1e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EOO01629.1 - 1.3e-09 37.5 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EOO01629.1 - 9.9e-07 28.3 0.1 9e-06 25.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EOO01629.1 - 0.00023 21.1 0.1 0.0005 20.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EOO01629.1 - 0.017 15.2 0.2 0.31 11.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EOO01629.1 - 0.06 13.3 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain L51_S25_CI-B8 PF05047.11 EOO01630.1 - 1.6e-14 53.3 0.0 2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.6 EOO01630.1 - 0.02 15.0 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Plant calmodulin-binding domain Methyltransf_32 PF13679.1 EOO01631.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EOO01631.1 - 0.041 13.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EOO01631.1 - 0.05 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EOO01631.1 - 0.057 13.1 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4132 PF13569.1 EOO01631.1 - 0.06 12.8 0.1 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) FtsJ PF01728.14 EOO01631.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EOO01631.1 - 0.083 11.5 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GidB PF02527.10 EOO01631.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EOO01631.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain IGF2_C PF08365.6 EOO01632.1 - 0.062 13.0 3.3 0.24 11.1 2.3 2.0 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide DUF914 PF06027.7 EOO01633.1 - 8.4e-103 343.7 16.4 1.1e-102 343.3 11.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EOO01633.1 - 6.4e-05 23.0 8.0 6.4e-05 23.0 5.5 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EOO01633.1 - 0.74 8.6 16.6 1.7 7.4 11.5 1.6 1 1 0 1 1 1 0 UAA transporter family DUF2516 PF10724.4 EOO01633.1 - 1.8 8.6 10.0 6.6 6.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) FUSC-like PF12805.2 EOO01633.1 - 9.5 5.0 10.1 0.46 9.3 1.2 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS eIF-5a PF01287.15 EOO01634.1 - 2.5e-05 24.1 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.3 EOO01634.1 - 0.38 11.3 16.0 0.27 11.7 1.2 2.4 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SLS PF14611.1 EOO01635.1 - 0.014 14.8 5.5 0.023 14.1 3.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator IL7 PF01415.11 EOO01635.1 - 0.049 13.2 6.0 0.11 12.1 3.3 2.1 1 1 0 1 1 1 0 Interleukin 7/9 family Spc7 PF08317.6 EOO01635.1 - 0.12 10.9 19.4 0.065 11.8 1.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF883 PF05957.8 EOO01635.1 - 0.12 12.7 6.6 0.25 11.7 0.8 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phage_GPO PF05929.6 EOO01635.1 - 0.28 10.3 7.3 0.19 10.9 3.7 1.6 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EOO01635.1 - 3.9 7.0 15.8 1.3 8.6 1.3 2.3 1 1 1 2 2 2 0 IncA protein YgaB PF14182.1 EOO01635.1 - 4.1 7.7 14.0 8.3 6.7 1.3 3.3 1 1 2 3 3 3 0 YgaB-like protein CENP-T PF15511.1 EOO01636.1 - 2.3e-101 340.0 34.8 1.6e-100 337.3 20.1 2.6 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EOO01636.1 - 6.4e-09 35.8 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EOO01636.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EOO01636.1 - 0.0025 17.8 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mem_trans PF03547.13 EOO01637.1 - 2.6e-18 65.5 0.1 7.2e-18 64.0 0.0 1.7 1 1 0 1 1 1 1 Membrane transport protein DUF1819 PF08849.6 EOO01637.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF2076 PF09849.4 EOO01638.1 - 4.9e-09 36.6 8.9 5.9e-09 36.3 6.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EOO01638.1 - 6e-06 26.0 3.6 9.8e-06 25.3 2.5 1.4 1 0 0 1 1 1 1 CHCH domain RAB3GAP2_N PF14655.1 EOO01638.1 - 0.083 11.8 0.1 0.086 11.8 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GCK PF07802.6 EOO01638.1 - 0.13 12.3 0.9 0.18 11.9 0.2 1.4 1 1 1 2 2 2 0 GCK domain COX6B PF02297.12 EOO01638.1 - 0.18 11.8 3.5 0.27 11.2 2.4 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Bindin PF02084.10 EOO01638.1 - 0.23 11.4 4.4 0.27 11.2 3.1 1.1 1 0 0 1 1 1 0 Bindin DUF605 PF04652.11 EOO01638.1 - 1 8.7 9.9 1.3 8.3 6.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF751 PF05421.6 EOO01639.1 - 0.13 12.5 1.9 3.5 7.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF751) PQ-loop PF04193.9 EOO01639.1 - 0.23 11.0 3.9 0.18 11.3 0.7 2.1 1 1 1 2 2 2 0 PQ loop repeat Pkinase PF00069.20 EOO01640.1 - 1e-52 178.9 0.0 7.8e-50 169.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01640.1 - 6.6e-33 113.8 0.0 1.5e-31 109.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO01640.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EOO01640.1 - 0.0014 17.5 0.1 0.0021 16.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EOO01640.1 - 0.021 14.5 0.2 0.088 12.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EOO01640.1 - 0.062 12.0 0.1 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Phostensin_N PF13916.1 EOO01640.1 - 2.4 8.1 5.3 2 8.4 0.1 2.6 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal SUR7 PF06687.7 EOO01641.1 - 5.4e-33 114.3 10.9 6.5e-33 114.0 7.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.6 EOO01641.1 - 0.097 12.2 13.3 0.016 14.8 6.3 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF2724 PF10893.3 EOO01641.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Claudin_2 PF13903.1 EOO01641.1 - 0.26 10.9 25.8 0.02 14.5 11.5 2.4 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EOO01641.1 - 4 6.6 9.4 0.37 9.9 3.4 1.5 2 0 0 2 2 2 0 Clc-like MFS_1 PF07690.11 EOO01643.1 - 7.6e-20 70.9 44.2 7.6e-20 70.9 30.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.1 EOO01644.1 - 8.9e-19 67.6 0.0 1.7e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EOO01644.1 - 5.5e-12 45.7 0.0 2.3e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EOO01644.1 - 1.4e-06 27.9 0.2 0.0061 16.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EOO01644.1 - 0.00097 19.2 0.0 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EOO01644.1 - 0.011 15.3 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EOO01644.1 - 0.15 11.7 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 EOO01645.1 - 2.2e-10 39.9 0.5 5e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO01645.1 - 2e-09 37.2 0.1 5.2e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EOO01645.1 - 0.14 10.6 68.9 0.01 14.3 36.4 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 NAC PF01849.13 EOO01646.1 - 2.2e-21 75.1 0.2 3.3e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 NAC domain Coq4 PF05019.8 EOO01647.1 - 1.1e-86 289.3 0.0 1.3e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SecE PF00584.15 EOO01649.1 - 1.3e-14 53.4 0.0 1.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Semialdhyde_dhC PF02774.13 EOO01650.1 - 4.2e-37 127.7 0.0 5.9e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EOO01650.1 - 8.9e-25 87.3 0.0 6.6e-24 84.5 0.0 2.4 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EOO01650.1 - 0.016 15.0 0.0 0.046 13.6 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EOO01650.1 - 0.067 13.7 0.1 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CPSase_L_D2 PF02786.12 EOO01651.1 - 4.4e-74 248.3 0.0 7.2e-74 247.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EOO01651.1 - 2.2e-35 120.8 0.0 4.5e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EOO01651.1 - 9.1e-34 115.8 0.0 1.8e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EOO01651.1 - 6e-19 68.4 0.1 1.2e-18 67.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EOO01651.1 - 1.7e-17 62.8 0.9 5.6e-17 61.1 0.6 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EOO01651.1 - 5.2e-16 58.3 0.0 8.6e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EOO01651.1 - 3.7e-09 36.2 0.0 7.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EOO01651.1 - 9.3e-09 34.8 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EOO01651.1 - 2.5e-07 30.2 0.0 0.017 14.8 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EOO01651.1 - 8.6e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EOO01651.1 - 7.2e-05 22.2 0.0 0.12 11.6 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EOO01651.1 - 0.00017 21.8 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.6 EOO01651.1 - 0.0008 18.9 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EOO01651.1 - 0.0075 15.4 0.1 2 7.5 0.0 2.7 2 1 1 3 3 3 2 HlyD family secretion protein DUF3182 PF11379.3 EOO01651.1 - 0.09 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Fumble PF03630.9 EOO01652.1 - 1.4e-131 438.3 0.0 1.4e-130 435.0 0.0 2.0 1 1 0 1 1 1 1 Fumble Thioredoxin PF00085.15 EOO01653.1 - 6.6e-25 86.8 0.2 9.9e-25 86.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EOO01653.1 - 3.1e-06 27.2 0.1 0.00049 20.1 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EOO01653.1 - 7e-06 26.2 0.5 3.1e-05 24.1 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EOO01653.1 - 0.0029 17.1 0.4 1 8.9 0.0 2.3 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EOO01653.1 - 0.0092 15.6 0.2 2.5 7.7 0.1 2.2 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EOO01653.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 EOO01653.1 - 0.054 12.2 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.1 EOO01653.1 - 0.06 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RGS PF00615.14 EOO01654.1 - 3.6e-05 23.8 0.1 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain IATP PF04568.7 EOO01654.1 - 0.11 12.5 0.2 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Peptidase_C1_2 PF03051.10 EOO01655.1 - 3.4e-158 526.7 0.0 4e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EOO01655.1 - 8.9e-08 32.2 0.0 0.00093 19.1 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease Methyltransf_23 PF13489.1 EOO01656.1 - 2.4e-24 85.8 0.0 3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO01656.1 - 2.6e-12 47.0 0.0 4.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO01656.1 - 4e-10 40.2 0.0 6.4e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01656.1 - 5.2e-10 39.1 0.0 1.1e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01656.1 - 5e-09 36.5 0.0 4.7e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO01656.1 - 5.4e-07 29.9 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO01656.1 - 3e-05 23.1 0.0 0.00017 20.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EOO01656.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EOO01656.1 - 0.0021 18.0 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO01656.1 - 0.0042 16.4 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EOO01656.1 - 0.0044 17.0 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EOO01656.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EOO01656.1 - 0.025 13.6 0.0 0.34 9.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EOO01656.1 - 0.038 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RNase_PH PF01138.16 EOO01657.1 - 1.1e-09 38.7 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EOO01657.1 - 0.0002 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Sugar_tr PF00083.19 EOO01658.1 - 4.3e-57 193.6 30.6 9.8e-39 133.1 8.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO01658.1 - 4.6e-20 71.6 33.1 9.4e-16 57.4 8.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RRM_6 PF14259.1 EOO01659.1 - 0.00042 20.2 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 EOO01662.1 - 2.6e-48 163.4 0.0 4.9e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EOO01662.1 - 2.7e-14 53.1 0.2 8.6e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PAT1 PF09770.4 EOO01662.1 - 0.36 9.0 42.9 0.039 12.2 26.3 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TBPIP PF07106.8 EOO01663.1 - 0.086 12.3 9.3 0.3 10.6 0.8 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EOO01663.1 - 0.25 11.0 12.7 1.4 8.6 1.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EOO01663.1 - 0.27 10.4 14.2 0.48 9.5 1.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.4 EOO01663.1 - 0.52 10.5 10.3 0.65 10.2 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.11 EOO01663.1 - 1.3 9.0 16.5 0.22 11.5 2.8 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Atg14 PF10186.4 EOO01663.1 - 2.3 7.0 16.7 0.19 10.6 3.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3708 PF12501.3 EOO01663.1 - 2.3 8.0 5.7 0.87 9.4 0.4 2.4 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter HK97-gp10_like PF04883.7 EOO01663.1 - 7.2 7.6 8.7 1.4 9.8 0.1 3.1 3 1 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component DUF972 PF06156.8 EOO01663.1 - 9.1 6.6 11.9 2.1 8.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Peptidase_C65 PF10275.4 EOO01664.1 - 6e-46 156.7 0.0 7.3e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain Asparaginase PF00710.15 EOO01665.1 - 1.2e-50 172.1 0.2 1.6e-50 171.8 0.1 1.1 1 0 0 1 1 1 1 Asparaginase Ras PF00071.17 EOO01666.1 - 7.5e-54 181.4 0.0 8.5e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO01666.1 - 8e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO01666.1 - 1e-06 28.0 0.0 1.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PI-PLC-Y PF00387.14 EOO01667.1 - 1.2e-38 131.7 0.4 2e-38 130.9 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.14 EOO01667.1 - 8.8e-24 83.5 0.1 2.1e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain BPL_LplA_LipB PF03099.14 EOO01669.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ApbA_C PF08546.6 EOO01670.1 - 9.4e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pox_H7 PF04787.7 EOO01670.1 - 0.00081 19.2 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Late protein H7 Saw1 PF11561.3 EOO01670.1 - 0.075 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 TPR_12 PF13424.1 EOO01671.1 - 6.3e-13 48.4 2.9 2.8e-05 23.9 0.1 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EOO01671.1 - 2.4e-05 24.5 6.8 0.31 11.4 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EOO01671.1 - 9.2e-05 22.2 3.9 2.1 8.3 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EOO01671.1 - 0.019 14.8 5.0 1.6 8.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO01671.1 - 0.11 13.2 10.0 0.74 10.6 0.2 5.8 5 2 2 7 7 7 0 Tetratricopeptide repeat Atg14 PF10186.4 EOO01671.1 - 0.11 11.3 5.1 0.26 10.1 3.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EOO01671.1 - 0.36 9.1 2.0 0.64 8.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AKNA PF12443.3 EOO01671.1 - 0.6 10.1 4.2 1.7 8.7 0.6 3.2 3 1 0 3 3 3 0 AT-hook-containing transcription factor IncA PF04156.9 EOO01671.1 - 3.1 7.3 9.4 2 7.9 4.5 2.2 2 0 0 2 2 2 0 IncA protein NUDIX PF00293.23 EOO01672.1 - 1.7e-05 24.5 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Romo1 PF10247.4 EOO01673.1 - 7.2e-19 67.7 9.1 6.6e-17 61.4 6.3 2.1 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Sas10_Utp3 PF04000.10 EOO01674.1 - 1.4e-17 63.6 0.5 1.4e-17 63.6 0.3 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family OmpA PF00691.15 EOO01674.1 - 0.019 15.3 2.9 0.032 14.6 2.0 1.5 1 1 0 1 1 1 0 OmpA family DUF310 PF03750.8 EOO01674.1 - 0.042 14.0 0.7 0.072 13.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF310) NPV_P10 PF05531.7 EOO01674.1 - 0.29 11.3 3.7 5 7.4 0.2 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Paramyxo_ncap PF00973.14 EOO01674.1 - 0.58 8.7 6.2 0.69 8.5 4.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.2 EOO01674.1 - 6.2 4.3 7.5 7.1 4.1 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CWC25 PF12542.3 EOO01675.1 - 1e-22 80.4 0.0 1e-22 80.4 0.0 3.1 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 EOO01675.1 - 5.9e-10 39.0 3.1 5.9e-10 39.0 2.2 2.6 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR RPA_interact_M PF14767.1 EOO01675.1 - 1.5 9.6 7.5 0.46 11.2 0.6 2.8 2 1 0 2 2 2 0 Replication protein A interacting middle TP_methylase PF00590.15 EOO01677.1 - 1.8e-43 148.6 0.8 1.4e-42 145.7 0.1 2.6 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EOO01677.1 - 1.6e-12 47.5 0.0 3.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EOO01677.1 - 4.7e-08 32.2 0.0 2.9e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EOO01677.1 - 4.7e-05 22.2 0.0 9e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central MoCF_biosynth PF00994.19 EOO01677.1 - 0.062 12.7 0.0 1.7 8.0 0.0 2.4 1 1 0 1 1 1 0 Probable molybdopterin binding domain p450 PF00067.17 EOO01678.1 - 9.2e-47 159.6 0.5 5.7e-46 156.9 0.3 1.8 1 1 0 1 1 1 1 Cytochrome P450 Gemini_AL1_M PF08283.6 EOO01678.1 - 0.069 12.9 0.1 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Geminivirus rep protein central domain Decorin_bind PF02352.10 EOO01678.1 - 0.095 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Decorin binding protein NUDIX PF00293.23 EOO01679.1 - 3.7e-17 62.2 0.0 5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain 4HBT PF03061.17 EOO01680.1 - 1.7e-06 28.0 0.1 3.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Ras PF00071.17 EOO01682.1 - 3.6e-54 182.5 0.0 4.2e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO01682.1 - 3.8e-16 59.6 0.0 5.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO01682.1 - 5.2e-09 35.5 0.0 8.6e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EOO01682.1 - 0.00061 18.9 0.0 0.00068 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EOO01682.1 - 0.0045 16.2 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EOO01682.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EOO01682.1 - 0.011 14.4 0.0 0.013 14.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 EOO01682.1 - 0.087 13.1 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EOO01682.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FAD_binding_7 PF03441.9 EOO01683.1 - 8.3e-53 179.3 0.3 1.2e-52 178.9 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EOO01683.1 - 2.5e-18 66.3 0.0 4.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase adh_short_C2 PF13561.1 EOO01684.1 - 1.3e-22 80.7 1.4 1.5e-22 80.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO01684.1 - 1.3e-09 38.2 5.5 1.6e-09 37.8 3.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01684.1 - 0.0015 18.2 0.8 0.0015 18.2 0.6 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.14 EOO01684.1 - 0.0056 15.7 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EOO01684.1 - 0.013 15.2 0.6 0.039 13.7 0.4 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EOO01684.1 - 0.057 13.6 0.1 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.16 EOO01684.1 - 0.12 11.8 0.6 1.2 8.4 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PI-PLC-X PF00388.14 EOO01685.1 - 1.2e-11 44.1 0.1 1.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SIR2 PF02146.12 EOO01686.1 - 2.5e-45 154.3 0.0 4.1e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family adh_short PF00106.20 EOO01687.1 - 5.7e-23 81.6 1.4 1.1e-20 74.1 1.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO01687.1 - 2.6e-09 36.9 0.1 1.2e-05 25.0 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EOO01687.1 - 4e-06 26.7 0.0 0.00047 20.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO01687.1 - 0.018 14.4 1.1 0.044 13.1 0.2 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1687 PF07955.6 EOO01688.1 - 1.4e-21 76.8 1.0 4.4e-21 75.2 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EOO01688.1 - 0.0057 16.7 0.0 0.38 10.8 0.0 2.5 2 1 0 2 2 2 1 ArsC family CMS1 PF14617.1 EOO01689.1 - 1.1e-87 293.2 2.1 1.3e-87 293.0 1.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EOO01689.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3441 PF11923.3 EOO01690.1 - 3.9e-32 110.1 0.8 1.7e-31 108.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EOO01690.1 - 3.5e-31 108.2 13.8 3.5e-31 108.2 9.6 3.2 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EOO01690.1 - 4.5e-24 84.1 0.0 1.2e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Myb_DNA-binding PF00249.26 EOO01691.1 - 9.7e-12 44.7 0.4 1.4e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EOO01691.1 - 1e-11 44.7 0.1 7.9e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 EOO01691.1 - 0.026 14.2 2.5 1.2 8.8 0.1 2.8 3 0 0 3 3 3 0 SLIDE SURF1 PF02104.10 EOO01692.1 - 7.7e-66 221.9 0.1 1.1e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Rsm22 PF09243.5 EOO01693.1 - 1.3e-30 106.3 0.0 5.5e-30 104.3 0.0 2.0 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Lactonase PF10282.4 EOO01693.1 - 1.5e-10 40.7 1.0 0.00017 20.8 0.0 3.8 3 1 1 4 4 4 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EOO01693.1 - 1.9e-07 29.7 0.0 0.00018 19.9 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Methyltransf_23 PF13489.1 EOO01693.1 - 3.1e-05 23.7 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fungal_trans_2 PF11951.3 EOO01694.1 - 0.069 11.7 0.0 0.39 9.2 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ribosomal_S4e PF00900.15 EOO01695.1 - 4.3e-31 106.4 0.2 8.7e-31 105.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EOO01695.1 - 2.3e-18 65.7 3.5 4.4e-18 64.8 2.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EOO01695.1 - 1.6e-06 27.4 0.0 3.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EOO01695.1 - 9.3e-06 25.1 1.1 9.3e-06 25.1 0.8 3.0 4 0 0 4 4 4 1 KOW motif RdRP PF05183.7 EOO01697.1 - 3e-182 607.3 0.0 3.9e-182 606.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1348 PF07080.6 EOO01698.1 - 2.6e-58 195.9 7.4 3.2e-58 195.5 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EOO01698.1 - 1.1e-06 29.0 1.7 1.5e-06 28.5 1.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EOO01698.1 - 0.00012 22.2 0.2 0.00018 21.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) dsDNA_bind PF01984.15 EOO01700.1 - 1.1e-35 121.8 12.1 1.4e-35 121.5 8.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EOO01700.1 - 0.021 15.0 1.5 0.024 14.8 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Alb1 PF09135.6 EOO01700.1 - 0.4 11.3 7.4 2.2 8.9 0.4 2.2 1 1 1 2 2 2 0 Alb1 WD40 PF00400.27 EOO01701.1 - 3.2e-23 80.6 14.0 2.9e-08 33.2 0.6 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat CDC45 PF02724.9 EOO01701.1 - 1.3 7.0 7.3 1.8 6.4 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sel1 PF08238.7 EOO01702.1 - 6.9e-45 150.4 29.0 7.5e-07 29.5 0.0 7.7 8 0 0 8 8 8 7 Sel1 repeat TPR_19 PF14559.1 EOO01702.1 - 1.8 8.9 16.6 13 6.2 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EOO01702.1 - 2.6 8.6 14.1 2.6 8.6 0.0 5.9 6 2 0 6 6 6 0 Tetratricopeptide repeat Pyridox_oxidase PF01243.15 EOO01703.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gln-synt_C PF00120.19 EOO01705.1 - 7.8e-62 208.7 0.0 9.9e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Alpha-amylase PF00128.19 EOO01706.1 - 1.3e-19 70.7 0.0 6.5e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EOO01706.1 - 5.9e-16 58.7 0.0 9.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EOO01706.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EOO01706.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EOO01706.1 - 0.098 13.2 0.3 0.26 11.8 0.2 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain His_biosynth PF00977.16 EOO01706.1 - 0.24 10.6 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Glyco_hydro_16 PF00722.16 EOO01707.1 - 1.1e-40 138.9 1.1 1.7e-40 138.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GFO_IDH_MocA_C PF02894.12 EOO01708.1 - 9.3e-18 64.0 0.5 7e-17 61.2 0.2 2.4 2 1 1 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EOO01708.1 - 5.7e-17 62.3 0.0 1e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Amidase PF01425.16 EOO01709.1 - 4.4e-69 233.4 1.0 2e-64 218.0 0.1 2.1 2 0 0 2 2 2 2 Amidase DUF1593 PF07632.6 EOO01710.1 - 4e-62 209.8 0.0 6.4e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) IU_nuc_hydro PF01156.14 EOO01710.1 - 0.039 13.1 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Methyltransf_23 PF13489.1 EOO01711.1 - 3.2e-18 65.9 0.0 4.9e-18 65.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO01711.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01711.1 - 4e-08 32.9 0.0 1.5e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO01711.1 - 2e-06 28.3 0.0 2.5e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01711.1 - 3.1e-06 27.5 0.0 1.5e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO01711.1 - 4.9e-06 26.8 0.0 8.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO01711.1 - 0.0038 16.3 0.0 0.0093 15.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EOO01711.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EOO01711.1 - 0.016 14.3 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EOO01711.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain CheR PF01739.13 EOO01711.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EOO01711.1 - 0.13 11.3 0.0 0.47 9.5 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EOO01711.1 - 0.16 11.1 0.2 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Sugar_tr PF00083.19 EOO01712.1 - 1.8e-73 247.6 18.2 5e-56 190.1 4.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Aldolase_II PF00596.16 EOO01713.1 - 3.9e-39 134.1 0.1 4.5e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Drf_FH1 PF06346.7 EOO01714.1 - 0.0002 20.8 24.2 0.0002 20.8 16.8 2.1 1 1 1 2 2 2 1 Formin Homology Region 1 Nop14 PF04147.7 EOO01715.1 - 0.072 11.0 11.7 0.091 10.6 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EOO01715.1 - 0.41 9.0 13.6 0.67 8.3 9.4 1.3 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 EOO01715.1 - 1.5 8.3 13.1 2.8 7.4 9.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EOO01715.1 - 2.8 5.8 13.7 4.6 5.1 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein GAS PF13851.1 EOO01716.1 - 6.6 5.8 66.8 3.8 6.6 17.1 3.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RNA_pol_Rpb1_5 PF04998.12 EOO01717.1 - 5.6e-86 288.2 0.3 1e-85 287.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EOO01717.1 - 3.6e-82 276.3 0.0 5.6e-82 275.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EOO01717.1 - 1.6e-68 229.8 0.1 5.1e-68 228.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.12 EOO01717.1 - 3e-29 100.8 0.1 9.7e-29 99.2 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 EOO01717.1 - 1.4e-17 63.9 0.0 3.4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Mito_carr PF00153.22 EOO01718.1 - 6.1e-75 247.0 1.9 2.9e-24 84.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_61 PF03443.9 EOO01719.1 - 2.1e-33 116.0 0.8 5.4e-31 108.1 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.12 EOO01720.1 - 2.1e-73 247.3 3.8 3.2e-56 190.9 1.6 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 EOO01720.1 - 0.051 12.0 0.5 0.099 11.0 0.1 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 71 FtsJ PF01728.14 EOO01721.1 - 2.4e-47 161.2 0.0 2.9e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase RRM_5 PF13893.1 EOO01722.1 - 3.4e-05 23.5 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EOO01722.1 - 7.6e-05 22.2 0.0 0.00024 20.6 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO01722.1 - 0.025 14.5 0.0 0.097 12.6 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 EOO01723.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) zf-RING_2 PF13639.1 EOO01723.1 - 0.004 16.9 1.7 0.004 16.9 1.2 2.0 2 0 0 2 2 2 1 Ring finger domain Ank PF00023.25 EOO01723.1 - 0.0049 16.6 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat TPR_14 PF13428.1 EOO01723.1 - 0.026 15.1 0.6 13 6.7 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-RING-like PF08746.6 EOO01723.1 - 1.9 8.5 8.2 1 9.3 2.6 2.5 3 0 0 3 3 3 0 RING-like domain zf-C3HC4_2 PF13923.1 EOO01723.1 - 2.7 8.1 6.9 0.3 11.1 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_39 PF01229.12 EOO01724.1 - 0.001 17.5 0.1 0.0014 17.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 GMC_oxred_C PF05199.8 EOO01725.1 - 2e-23 83.2 0.3 3.7e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EOO01725.1 - 3.9e-23 82.0 0.0 6.1e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EOO01725.1 - 2.5e-08 33.4 1.4 5.9e-08 32.2 0.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 EOO01725.1 - 0.00088 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_61 PF03443.9 EOO01726.1 - 3.4e-39 134.9 0.0 4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_C53 PF05550.6 EOO01726.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 CH PF00307.26 EOO01727.1 - 1.9e-63 211.2 0.0 1.8e-16 60.1 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EOO01727.1 - 5.9e-08 32.7 0.3 1.6e-06 28.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EOO01727.1 - 2.3e-05 23.3 1.6 0.4 10.1 0.2 3.7 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 EOO01727.1 - 0.009 15.6 0.0 42 3.8 0.0 3.8 4 0 0 4 4 4 0 CAMSAP CH domain EF-hand_6 PF13405.1 EOO01727.1 - 0.036 13.9 3.7 0.12 12.3 0.1 3.2 4 0 0 4 4 4 0 EF-hand domain MBOAT PF03062.14 EOO01728.1 - 2.7e-30 105.5 18.0 2.7e-30 105.5 12.4 2.5 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EOO01728.1 - 6.7e-06 26.0 4.4 1.7e-05 24.7 3.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L18e PF00828.14 EOO01729.1 - 4.7e-25 88.4 0.0 4.7e-25 88.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Sugar_tr PF00083.19 EOO01730.1 - 4e-33 114.6 1.0 5.4e-33 114.2 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OST3_OST6 PF04756.8 EOO01731.1 - 1.8e-20 73.1 1.2 2.5e-20 72.6 0.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family QCR10 PF09796.4 EOO01731.1 - 0.98 9.1 4.8 0.3 10.7 0.2 2.3 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) NADH-u_ox-rdase PF10785.4 EOO01731.1 - 4.2 7.6 5.6 1.7 8.9 0.0 2.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Sedlin_N PF04628.8 EOO01732.1 - 2.8e-18 66.0 0.0 4.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.16 EOO01732.1 - 1.1e-09 38.1 0.0 5.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sybindin PF04099.7 EOO01732.1 - 0.049 13.3 0.0 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Sybindin-like family Cache_3 PF14827.1 EOO01732.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase IU_nuc_hydro PF01156.14 EOO01735.1 - 1.1e-22 80.7 0.0 1.3e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Xan_ur_permease PF00860.15 EOO01737.1 - 2.1e-40 138.4 21.0 9.9e-40 136.2 14.5 1.9 1 1 0 1 1 1 1 Permease family PH_10 PF15411.1 EOO01738.1 - 5.9e-46 155.4 0.2 1.1e-45 154.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EOO01738.1 - 2.1e-31 107.8 0.0 4.6e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EOO01738.1 - 5.2e-21 75.3 0.0 8.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EOO01738.1 - 1.5e-08 34.1 0.0 3.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain NUDE_C PF04880.8 EOO01739.1 - 7.7e-23 81.6 1.0 7.7e-23 81.6 0.7 2.1 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region IncA PF04156.9 EOO01739.1 - 0.0018 17.8 32.2 0.068 12.7 13.6 2.2 1 1 1 2 2 2 2 IncA protein DUF904 PF06005.7 EOO01739.1 - 0.0021 18.3 7.5 0.0021 18.3 5.2 3.5 1 1 1 2 2 1 1 Protein of unknown function (DUF904) Filament PF00038.16 EOO01739.1 - 0.028 13.8 28.9 0.2 11.0 20.1 1.9 1 1 0 1 1 1 0 Intermediate filament protein WEMBL PF05701.6 EOO01739.1 - 0.028 12.8 28.1 0.037 12.4 19.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EOO01739.1 - 0.064 13.1 30.6 2.7 7.8 8.7 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.8 EOO01739.1 - 0.12 11.8 9.5 0.059 12.8 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) EF1G PF00647.14 EOO01739.1 - 0.12 12.0 0.9 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Laminin_II PF06009.7 EOO01739.1 - 1 9.1 15.0 98 2.6 0.1 3.4 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.6 EOO01739.1 - 2.2 8.0 28.5 3.8 7.2 12.0 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.4 EOO01739.1 - 2.4 8.1 19.0 5.4e+02 0.4 13.2 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein IFT57 PF10498.4 EOO01739.1 - 2.5 6.7 22.1 0.023 13.4 5.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FliD_N PF02465.13 EOO01739.1 - 2.8 8.3 7.7 1.5 9.2 0.2 2.9 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus AAA_13 PF13166.1 EOO01739.1 - 2.9 6.2 21.5 4 5.7 14.9 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 EOO01739.1 - 3.3 7.5 33.4 15 5.4 13.9 3.2 1 1 1 2 2 2 0 Tropomyosin like ACC_central PF08326.7 EOO01740.1 - 5.3e-258 857.8 0.0 6.7e-258 857.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EOO01740.1 - 1e-177 591.4 0.0 1.3e-177 591.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EOO01740.1 - 6.2e-52 175.9 0.0 1.2e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EOO01740.1 - 3.6e-24 84.9 0.1 7.2e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EOO01740.1 - 2.1e-20 72.7 0.0 2e-18 66.3 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EOO01740.1 - 1.7e-16 59.5 0.1 4.2e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EOO01740.1 - 4.8e-10 39.4 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EOO01740.1 - 0.0075 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EOO01740.1 - 0.017 14.7 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like DUF1722 PF08349.6 EOO01741.1 - 0.039 13.8 0.0 0.4 10.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1722) Sugar_tr PF00083.19 EOO01742.1 - 8.8e-63 212.4 30.4 1.1e-62 212.1 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01742.1 - 1.4e-23 83.2 28.0 2.1e-23 82.6 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 EOO01743.1 - 3.3e-51 174.2 0.0 4.5e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain TNF PF00229.13 EOO01744.1 - 0.0061 16.1 0.0 12 5.4 0.0 3.9 2 1 3 5 5 5 1 TNF(Tumour Necrosis Factor) family RasGAP_C PF03836.10 EOO01744.1 - 0.01 15.5 0.1 3.7 7.2 0.0 2.8 1 1 2 3 3 3 0 RasGAP C-terminus DUF2072 PF09845.4 EOO01744.1 - 0.11 12.4 0.1 7.9 6.4 0.0 2.5 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) Abhydrolase_6 PF12697.2 EOO01745.1 - 3.8e-28 98.9 0.0 5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO01745.1 - 2.8e-23 82.6 0.0 4.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO01745.1 - 1.4e-11 44.3 0.0 6.1e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EOO01745.1 - 7e-05 21.4 0.0 0.0007 18.1 0.0 2.0 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EOO01745.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Amidase PF01425.16 EOO01746.1 - 1.5e-37 129.5 0.4 1.7e-37 129.3 0.3 1.1 1 0 0 1 1 1 1 Amidase ALS_ss_C PF10369.4 EOO01746.1 - 0.14 11.8 0.0 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Small subunit of acetolactate synthase MR_MLE_C PF13378.1 EOO01747.1 - 1.4e-12 47.5 0.0 4.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EOO01747.1 - 2.1e-12 47.3 0.0 4.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EOO01747.1 - 1.3e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 3Beta_HSD PF01073.14 EOO01748.1 - 1.3e-06 27.3 0.0 1.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EOO01748.1 - 3.1e-06 26.7 0.2 1.4e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO01748.1 - 5.9e-06 26.4 0.1 1.6e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EOO01748.1 - 0.00012 21.0 0.0 0.00036 19.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Peptidase_S8 PF00082.17 EOO01749.1 - 1.3e-25 90.0 11.2 1.5e-25 89.9 7.7 1.0 1 0 0 1 1 1 1 Subtilase family DUF21 PF01595.15 EOO01749.1 - 0.11 11.8 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 Big_2 PF02368.13 EOO01750.1 - 0.18 11.6 2.1 6.6 6.6 0.1 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 2) Saccharop_dh PF03435.13 EOO01751.1 - 4.4e-11 42.3 0.0 1.2e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase DUF3150 PF11348.3 EOO01751.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Het-C PF07217.6 EOO01752.1 - 4.2e-127 424.8 0.2 7.8e-101 338.1 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C DUF883 PF05957.8 EOO01752.1 - 8.6e-05 22.8 4.2 0.0028 18.0 1.1 3.8 2 1 2 4 4 4 1 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 EOO01752.1 - 0.00065 19.5 6.4 0.37 10.7 0.1 4.9 2 2 4 6 6 6 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Chlorosome_CsmC PF11098.3 EOO01752.1 - 0.0067 16.1 8.8 0.026 14.2 1.1 2.8 1 1 1 2 2 2 1 Chlorosome envelope protein C YtxH PF12732.2 EOO01752.1 - 0.0082 16.4 2.4 1.9 8.9 0.2 3.9 2 1 1 3 3 3 1 YtxH-like protein PRD PF00874.15 EOO01752.1 - 0.022 14.8 0.1 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 PRD domain Apolipoprotein PF01442.13 EOO01752.1 - 0.074 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.6 EOO01752.1 - 0.075 12.7 7.7 0.12 12.1 0.8 3.6 2 2 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.6 EOO01752.1 - 0.095 12.7 1.9 0.48 10.4 0.2 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ISG65-75 PF11727.3 EOO01752.1 - 1.2 8.1 6.0 0.36 9.8 1.0 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Methyltransf_2 PF00891.13 EOO01753.1 - 2.2e-30 105.6 0.0 4.5e-30 104.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Sugar_tr PF00083.19 EOO01754.1 - 1.9e-102 343.1 21.7 2.3e-102 342.9 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01754.1 - 2.9e-22 78.8 17.1 2.9e-22 78.8 11.8 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP-synt_ab PF00006.20 EOO01755.1 - 1e-71 240.8 0.0 1.9e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EOO01755.1 - 1.6e-26 93.0 0.1 5.4e-26 91.2 0.1 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EOO01755.1 - 1.2e-15 57.4 2.8 3.3e-15 56.0 2.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EOO01755.1 - 0.0059 16.4 1.4 0.014 15.2 0.5 2.1 2 0 0 2 2 2 1 HAS barrel domain Arch_ATPase PF01637.13 EOO01755.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MFS_1 PF07690.11 EOO01756.1 - 1e-32 113.2 23.3 5.8e-32 110.7 15.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 EOO01756.1 - 0.0093 15.2 2.9 0.0093 15.2 2.0 3.1 3 1 0 3 3 3 1 ABC-2 family transporter protein ESSS PF10183.4 EOO01756.1 - 0.0098 16.2 0.1 0.039 14.3 0.1 2.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aldedh PF00171.17 EOO01757.1 - 1.4e-124 415.9 0.0 1.9e-124 415.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 EOO01757.1 - 4.4e-27 95.0 0.9 9.2e-27 93.9 0.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO01757.1 - 2.9e-08 33.5 0.7 5.4e-08 32.7 0.5 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO01757.1 - 2.1e-07 30.9 0.1 4.5e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LuxC PF05893.9 EOO01757.1 - 2.8e-07 29.6 0.1 2.4e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) 3HCDH_N PF02737.13 EOO01757.1 - 0.00032 20.3 0.5 0.0024 17.5 0.2 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_3 PF13474.1 EOO01759.1 - 0.00087 19.3 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EOO01759.1 - 0.0021 17.9 0.4 0.0041 17.0 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain Carb_kinase PF01256.12 EOO01760.1 - 1.9e-56 191.1 0.1 2.6e-56 190.6 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EOO01760.1 - 0.00035 19.8 0.1 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.19 EOO01760.1 - 0.0012 18.0 0.0 0.0041 16.2 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EOO01760.1 - 0.015 14.4 0.1 0.052 12.7 0.1 1.9 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase CD99L2 PF12301.3 EOO01761.1 - 0.028 14.1 1.4 0.04 13.6 0.9 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 APG12 PF04110.8 EOO01762.1 - 9.3e-26 89.8 0.0 1.3e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EOO01762.1 - 0.0004 20.3 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Cellulase PF00150.13 EOO01763.1 - 2.3e-12 46.7 0.5 2.3e-12 46.7 0.4 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) BCCT PF02028.12 EOO01763.1 - 0.19 9.9 3.6 0.29 9.3 2.5 1.1 1 0 0 1 1 1 0 BCCT family transporter Dfp1_Him1_M PF08630.5 EOO01764.1 - 1.4e-44 150.8 0.0 3e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EOO01764.1 - 1.6e-24 85.3 0.3 3e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EOO01764.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EOO01764.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Adaptin_binding PF10199.4 EOO01764.1 - 0.82 9.9 7.1 0.18 12.1 0.2 3.0 3 2 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 PNP_UDP_1 PF01048.15 EOO01765.1 - 1.1e-34 119.4 0.7 1.4e-34 119.0 0.5 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily F-actin_cap_A PF01267.12 EOO01766.1 - 1e-92 310.0 0.0 1.2e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Med13_C PF06333.7 EOO01768.1 - 9.2e-54 182.5 0.0 1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal WD40 PF00400.27 EOO01769.1 - 5e-16 57.8 1.5 1.5e-06 27.8 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat IKI3 PF04762.7 EOO01769.1 - 0.0029 15.4 0.0 0.0041 15.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 EOO01769.1 - 0.014 15.1 0.1 0.15 11.7 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EOO01769.1 - 0.016 13.5 0.0 0.039 12.2 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 EOO01769.1 - 0.091 12.4 0.0 16 5.3 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ParA PF10609.4 EOO01770.1 - 2.9e-33 113.5 0.3 4.5e-33 112.9 0.2 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EOO01770.1 - 0.011 15.1 0.1 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EOO01770.1 - 0.041 13.4 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.1 EOO01770.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinocilin protein Glyco_hydro_7 PF00840.15 EOO01771.1 - 5e-213 707.2 24.3 5.8e-213 707.0 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 OCD_Mu_crystall PF02423.10 EOO01772.1 - 5.7e-20 71.2 0.3 1.6e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family DUF4054 PF13262.1 EOO01772.1 - 0.024 14.8 0.0 0.083 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Aminotran_1_2 PF00155.16 EOO01773.1 - 1.1e-36 126.5 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EOO01773.1 - 0.0061 15.1 0.0 0.0094 14.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EOO01773.1 - 0.066 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1593 PF07632.6 EOO01774.1 - 8.4e-72 241.5 0.0 1.1e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EOO01774.1 - 0.0027 16.1 0.0 0.0035 15.7 0.0 1.2 1 0 0 1 1 1 1 REJ domain SIR2 PF02146.12 EOO01775.1 - 1.1e-21 77.3 0.0 2.1e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.5 EOO01775.1 - 0.26 10.8 3.5 5.7 6.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) NAD_binding_10 PF13460.1 EOO01776.1 - 5.5e-13 49.3 1.6 6.7e-13 49.0 1.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO01776.1 - 3e-08 33.4 0.0 6.2e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 EOO01776.1 - 3.2e-06 25.8 0.0 5.5e-05 21.8 0.0 2.0 1 1 1 2 2 2 1 HIM1 NmrA PF05368.8 EOO01776.1 - 8.9e-06 25.1 0.5 3.7e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EOO01776.1 - 0.00069 18.6 0.0 1.7 7.4 0.0 2.9 1 1 2 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.14 EOO01776.1 - 0.02 13.5 0.0 0.17 10.5 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EOO01776.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Atx10homo_assoc PF09759.4 EOO01777.1 - 1e-11 44.4 0.0 3.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain NeA_P2 PF12312.3 EOO01777.1 - 0.65 9.1 3.4 1.2 8.2 2.3 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Zip PF02535.17 EOO01777.1 - 2.1 7.2 22.3 3.5 6.5 15.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Arrestin_N PF00339.24 EOO01778.1 - 2.7e-15 56.4 0.0 4.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EOO01778.1 - 1.1e-14 54.6 0.1 3.3e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EOO01778.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like RPN7 PF10602.4 EOO01779.1 - 3.7e-56 189.3 1.6 4.5e-56 189.0 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EOO01779.1 - 4e-14 52.7 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EOO01779.1 - 0.15 12.7 1.9 2.2 9.1 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2381 PF09544.5 EOO01780.1 - 0.015 14.3 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DHBP_synthase PF00926.14 EOO01781.1 - 8.7e-74 246.9 0.0 4.6e-73 244.5 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Pro_CA PF00484.14 EOO01782.1 - 2.9e-45 153.9 0.1 3.5e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 Carbonic anhydrase TauD PF02668.11 EOO01783.1 - 1.5e-41 142.7 0.1 2.3e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MOZ_SAS PF01853.13 EOO01784.1 - 5.4e-80 267.0 0.1 7.5e-80 266.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family CD99L2 PF12301.3 EOO01785.1 - 0.0066 16.1 1.3 0.0083 15.8 0.3 1.5 1 1 1 2 2 2 1 CD99 antigen like protein 2 DUF2371 PF10177.4 EOO01785.1 - 0.098 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) EVC2_like PF12297.3 EOO01785.1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein M_domain PF12938.2 EOO01785.1 - 0.33 10.7 1.4 0.42 10.3 1.0 1.1 1 0 0 1 1 1 0 M domain of GW182 ApbA PF02558.11 EOO01786.1 - 7.3e-28 96.9 0.0 1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EOO01786.1 - 7.3e-25 87.3 0.0 1.8e-24 86.1 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DUF3786 PF12654.2 EOO01787.1 - 0.015 14.6 0.3 0.049 12.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Reo_sigmaC PF04582.7 EOO01787.1 - 0.31 10.1 37.2 0.23 10.6 2.7 4.9 2 1 3 5 5 5 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 EOO01788.1 - 3.5e-46 157.5 35.2 6.7e-46 156.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO01788.1 - 4.1e-10 38.4 2.8 6.2e-10 37.9 1.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EOO01788.1 - 1.7e-08 33.4 25.2 1.6e-07 30.3 17.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 EOO01788.1 - 0.74 9.5 7.2 0.058 13.1 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) PAS PF00989.19 EOO01789.1 - 0.0023 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Sugar_tr PF00083.19 EOO01790.1 - 5e-69 233.0 22.9 5.8e-69 232.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01790.1 - 4.5e-13 48.6 26.6 1.3e-12 47.1 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01790.1 - 0.00076 17.9 25.2 0.013 13.9 4.1 3.6 2 2 1 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EOO01790.1 - 0.11 12.2 4.4 0.36 10.6 0.1 3.3 3 0 0 3 3 3 0 MFS_1 like family Thiolase_N PF00108.18 EOO01791.1 - 5.4e-78 261.6 2.6 8e-78 261.0 1.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EOO01791.1 - 4.7e-44 148.7 0.2 9.1e-44 147.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EOO01791.1 - 0.072 13.1 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PEX11 PF05648.9 EOO01792.1 - 3.6e-74 248.7 0.3 4.1e-74 248.6 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ENTH PF01417.15 EOO01793.1 - 8.6e-50 167.7 0.1 1.5e-49 166.9 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EOO01793.1 - 0.0048 15.6 0.0 0.007 15.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 EOO01793.1 - 0.019 14.4 4.0 0.023 14.2 0.3 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 EOO01793.1 - 0.033 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.1 EOO01793.1 - 0.098 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF1510 PF07423.6 EOO01793.1 - 1.2 8.4 11.2 0.81 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Yae1_N PF09811.4 EOO01793.1 - 6.6 6.3 6.8 2.1 7.9 0.6 2.8 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Miro PF08477.8 EOO01794.1 - 2.2e-35 121.6 0.0 3.6e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EOO01794.1 - 1e-33 114.9 0.0 2.2e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EOO01794.1 - 5.9e-32 108.7 0.2 1.3e-31 107.6 0.2 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EOO01794.1 - 7.2e-24 84.0 0.0 1e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 EOO01794.1 - 1.6e-08 34.5 0.6 0.00035 20.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EOO01794.1 - 5.1e-08 31.6 2.7 0.0046 16.1 0.1 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EOO01794.1 - 7.2e-08 32.3 0.0 0.00017 21.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.1 EOO01794.1 - 2.4e-06 26.9 2.7 0.07 13.0 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.1 EOO01794.1 - 3.2e-06 27.2 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EOO01794.1 - 1.3e-05 24.5 0.0 0.033 13.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EOO01794.1 - 3e-05 23.9 0.1 0.33 10.7 0.1 3.2 2 1 1 3 3 3 2 Dynamin family EF-hand_5 PF13202.1 EOO01794.1 - 5e-05 22.4 4.9 0.056 12.8 1.4 3.0 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 EOO01794.1 - 0.00018 21.6 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EOO01794.1 - 0.0014 18.1 0.0 1.3 8.4 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EOO01794.1 - 0.0015 18.8 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EOO01794.1 - 0.0018 17.4 0.0 0.87 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EOO01794.1 - 0.0024 17.5 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EOO01794.1 - 0.0062 15.4 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EOO01794.1 - 0.0071 16.5 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EOO01794.1 - 0.011 15.1 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 EOO01794.1 - 0.013 15.1 2.9 2.6 7.7 0.5 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.1 EOO01794.1 - 0.013 15.1 0.6 0.059 13.0 0.1 2.1 2 0 0 2 2 2 0 EF hand AAA_28 PF13521.1 EOO01794.1 - 0.016 15.1 0.0 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 EOO01794.1 - 0.021 13.6 0.1 0.62 8.8 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.9 EOO01794.1 - 0.021 14.5 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EOO01794.1 - 0.022 14.2 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EOO01794.1 - 0.038 13.6 0.1 1.9 8.1 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Septin PF00735.13 EOO01794.1 - 0.04 12.9 0.0 0.25 10.3 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EOO01794.1 - 0.054 13.8 0.1 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EOO01794.1 - 0.079 12.6 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 EOO01794.1 - 0.12 12.2 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EOO01794.1 - 0.13 11.5 0.0 5.7 6.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain zf-RING_2 PF13639.1 EOO01796.1 - 6.3e-11 41.9 5.6 9.7e-11 41.3 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EOO01796.1 - 2.9e-07 30.2 0.8 4.9e-07 29.5 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EOO01796.1 - 5.5e-07 29.6 1.0 1.1e-06 28.6 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EOO01796.1 - 9e-05 22.0 2.6 0.0002 20.9 1.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO01796.1 - 0.00017 21.5 4.7 0.00028 20.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO01796.1 - 0.00018 21.0 3.5 0.00031 20.3 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO01796.1 - 0.0043 16.7 2.8 0.0081 15.8 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Rad50_zn_hook PF04423.9 EOO01796.1 - 0.012 15.0 4.5 0.044 13.2 0.2 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EOO01796.1 - 0.039 13.6 3.2 0.071 12.8 0.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 EOO01796.1 - 0.096 12.8 3.1 9.2 6.4 0.0 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 EOO01796.1 - 0.11 12.1 5.4 0.56 9.8 3.9 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EOO01796.1 - 0.12 12.3 3.4 3.2 7.7 2.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EOO01796.1 - 0.33 10.7 3.6 1 9.1 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Fungal_trans PF04082.13 EOO01798.1 - 0.0066 15.3 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M24 PF00557.19 EOO01799.1 - 2.8e-52 177.3 0.1 3.6e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EOO01799.1 - 2.7e-38 130.3 0.0 4.6e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TFIIE_beta PF02186.10 EOO01800.1 - 7.7e-06 25.8 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain HTH_11 PF08279.7 EOO01800.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 HTH domain Pantoate_transf PF02548.10 EOO01801.1 - 1.2e-104 349.1 0.2 1.3e-104 348.9 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EOO01801.1 - 1.4e-11 44.1 0.5 1.8e-11 43.7 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Flavokinase PF01687.12 EOO01802.1 - 6.9e-34 116.4 0.0 8e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.11 EOO01803.1 - 2.6e-37 128.3 32.3 3.1e-37 128.0 22.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO01803.1 - 6.4e-06 24.6 1.8 6.4e-06 24.6 1.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EOO01803.1 - 0.00053 18.2 0.9 0.00053 18.2 0.6 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector Inositol_P PF00459.20 EOO01804.1 - 2.4e-52 177.9 2.3 5e-52 176.8 1.6 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Fapy_DNA_glyco PF01149.19 EOO01805.1 - 6.7e-27 94.1 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EOO01805.1 - 4e-20 71.3 0.0 7.6e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EOO01805.1 - 8.1e-05 21.3 4.2 0.025 13.1 0.0 2.9 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) KicB PF03882.9 EOO01805.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 KicB killing factor RNA_polI_A34 PF08208.6 EOO01805.1 - 3.9 7.1 24.6 6.3 6.4 17.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-Nse PF11789.3 EOO01806.1 - 7.2e-22 76.6 0.2 1.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EOO01806.1 - 0.00034 20.2 0.2 0.00074 19.1 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EOO01806.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1840 PF08895.6 EOO01806.1 - 1 9.4 6.0 0.68 9.9 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) UQ_con PF00179.21 EOO01807.1 - 2.3e-35 121.0 0.1 2.8e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_MCEL PF03291.11 EOO01808.1 - 4.9e-67 226.1 0.0 3.2e-46 157.7 0.0 2.4 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EOO01808.1 - 8.5e-10 39.0 0.0 0.00065 20.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EOO01808.1 - 3.1e-08 34.1 0.0 7.9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO01808.1 - 2.3e-07 31.2 0.0 4.1e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO01808.1 - 7.7e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO01808.1 - 1.5e-06 28.4 0.0 8.1e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01808.1 - 1.9e-06 27.5 0.0 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EOO01808.1 - 5.8e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.6 EOO01808.1 - 0.13 10.9 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Raftlin PF15250.1 EOO01808.1 - 0.2 10.1 0.0 0.2 10.1 0.0 1.6 2 0 0 2 2 2 0 Raftlin DDRGK PF09756.4 EOO01808.1 - 1.7 8.0 6.3 0.19 11.1 0.3 2.2 2 0 0 2 2 2 0 DDRGK domain Ribosomal_L7Ae PF01248.21 EOO01809.1 - 4.5e-20 70.9 0.6 7.7e-20 70.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.7 EOO01809.1 - 0.047 12.4 0.1 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) PH PF00169.24 EOO01810.1 - 0.00043 20.4 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 EOO01810.1 - 0.016 14.7 0.2 0.036 13.5 0.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CK2S PF15011.1 EOO01810.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate SseC PF04888.7 EOO01810.1 - 0.27 10.5 5.8 0.037 13.3 0.5 1.9 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family p450 PF00067.17 EOO01811.1 - 6.3e-27 94.2 0.0 1.3e-23 83.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 PDZ_1 PF12812.2 EOO01811.1 - 0.043 13.7 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 PDZ-like domain DUF572 PF04502.8 EOO01812.1 - 1.3e-55 188.8 0.0 1.7e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) NUC153 PF08159.7 EOO01813.1 - 5.7e-15 54.5 1.4 1.4e-14 53.3 1.0 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EOO01813.1 - 0.00016 21.4 0.1 0.001 18.8 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat eIF2A PF08662.6 EOO01813.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A RFXA_RFXANK_bdg PF15289.1 EOO01813.1 - 2.7 8.2 7.6 11 6.2 0.7 2.4 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DSBA PF01323.15 EOO01814.1 - 7e-24 84.4 0.0 9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EOO01814.1 - 0.0087 16.2 0.0 3.5 7.8 0.0 2.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EOO01814.1 - 0.015 15.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 EOO01814.1 - 0.047 13.5 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain Cyt-b5 PF00173.23 EOO01815.1 - 1.2e-25 89.0 0.3 1.5e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 EOO01815.1 - 0.12 12.3 0.8 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 YqzH-like protein Nup96 PF12110.3 EOO01816.1 - 4.4e-90 301.7 0.1 6.2e-90 301.2 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EOO01816.1 - 3.4e-48 163.0 0.0 5.7e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EOO01816.1 - 6.6e-18 64.9 350.6 2.6e-10 40.5 34.5 9.7 5 2 4 9 9 9 4 Nucleoporin FG repeat region Peptidase_S10 PF00450.17 EOO01817.1 - 5.4e-70 236.6 0.2 8.1e-70 236.0 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EOO01817.1 - 0.0021 17.9 0.0 0.01 15.7 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family HLH PF00010.21 EOO01818.1 - 2.1e-17 62.5 0.0 1.1e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FBPase PF00316.15 EOO01819.1 - 1.2e-123 412.1 0.1 1.3e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Transket_pyr PF02779.19 EOO01820.1 - 2.8e-42 144.2 0.0 4.5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EOO01820.1 - 1.4e-34 118.6 0.0 3.1e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PHY PF00360.15 EOO01821.1 - 5.7e-29 100.5 0.0 1.1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EOO01821.1 - 1.2e-18 66.8 0.2 2.1e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EOO01821.1 - 2.6e-16 60.1 0.0 1.5e-15 57.6 0.0 2.4 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 EOO01821.1 - 7.4e-16 58.1 0.1 6e-15 55.2 0.0 2.7 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EOO01821.1 - 3.2e-12 46.2 0.6 1e-11 44.6 0.4 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EOO01821.1 - 3.5e-09 37.0 0.0 1.4e-08 35.1 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EOO01821.1 - 0.075 13.4 0.0 0.73 10.2 0.0 2.5 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.6 EOO01821.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold AAA PF00004.24 EOO01822.1 - 8.2e-17 61.6 0.0 1.3e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO01822.1 - 0.00011 22.3 0.2 0.0006 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO01822.1 - 0.00048 20.1 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EOO01822.1 - 0.00079 19.1 0.2 0.0035 17.0 0.0 2.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EOO01822.1 - 0.0016 18.1 0.1 0.0046 16.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EOO01822.1 - 0.0089 16.8 0.1 0.02 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EOO01822.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EOO01822.1 - 0.019 14.3 0.1 0.032 13.6 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 EOO01822.1 - 0.057 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EOO01822.1 - 0.066 13.1 0.7 0.36 10.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EOO01822.1 - 0.074 12.6 0.2 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EOO01822.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EOO01822.1 - 0.12 11.7 0.6 0.3 10.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EOO01822.1 - 0.14 11.3 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EOO01822.1 - 0.16 11.6 0.1 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 NTPase MFS_1 PF07690.11 EOO01823.1 - 8.9e-22 77.2 20.5 1.4e-21 76.6 14.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin PF00085.15 EOO01824.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EOO01824.1 - 0.0092 16.1 0.1 0.34 11.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EOO01824.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.1 EOO01824.1 - 0.054 13.0 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin RVP_2 PF08284.6 EOO01824.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Thioredoxin_7 PF13899.1 EOO01824.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Slu7 PF11708.3 EOO01827.1 - 1.3e-77 260.7 20.6 1.3e-77 260.7 14.3 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 EOO01827.1 - 0.00082 19.1 3.2 0.0014 18.4 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EOO01827.1 - 0.0049 16.5 0.9 0.0099 15.5 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Sigma70_r2 PF04542.9 EOO01827.1 - 0.056 13.0 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 region 2 zf-CCHC_6 PF15288.1 EOO01827.1 - 0.098 12.3 4.0 0.24 11.1 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2404 PF10296.4 EOO01829.1 - 2.6e-33 114.0 0.0 2.2e-32 111.0 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EOO01829.1 - 0.00079 19.5 0.0 0.3 11.3 0.0 2.4 1 1 1 2 2 2 2 PH domain Ribosomal_L37e PF01907.14 EOO01833.1 - 0.067 13.0 0.7 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L37e DNA_pol_B PF00136.16 EOO01835.1 - 3.5e-99 332.7 0.1 4.4e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 EOO01835.1 - 3e-17 62.3 3.2 3e-17 62.3 2.2 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EOO01835.1 - 0.002 17.9 2.3 0.0044 16.8 1.6 1.5 1 0 0 1 1 1 1 Double zinc ribbon DUF2116 PF09889.4 EOO01835.1 - 0.14 12.0 4.9 0.57 10.0 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ank_2 PF12796.2 EOO01836.1 - 3.2e-10 40.1 0.2 2.5e-09 37.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EOO01836.1 - 1.7e-07 31.5 1.0 0.0001 22.7 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO01836.1 - 3.7e-07 30.1 0.1 0.042 14.1 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EOO01836.1 - 3.9e-07 29.5 1.3 0.068 13.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EOO01836.1 - 7.8e-06 25.6 0.8 0.15 12.4 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Dioxygenase_C PF00775.16 EOO01837.1 - 7.8e-10 38.3 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase AAA_13 PF13166.1 EOO01838.1 - 0.00017 20.2 8.6 0.00026 19.6 6.0 1.3 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EOO01838.1 - 0.00031 20.4 16.1 0.035 13.7 0.9 2.4 2 0 0 2 2 2 2 IncA protein TMF_DNA_bd PF12329.3 EOO01838.1 - 0.018 14.8 3.1 0.018 14.8 2.2 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.6 EOO01838.1 - 0.022 14.1 9.6 0.18 11.1 1.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.4 EOO01838.1 - 0.032 14.3 2.8 0.032 14.3 2.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 EOO01838.1 - 0.045 13.7 16.9 0.19 11.6 5.0 3.1 3 0 0 3 3 3 0 FlxA-like protein Fib_alpha PF08702.5 EOO01838.1 - 0.046 13.8 9.1 0.052 13.6 4.2 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SCIMP PF15050.1 EOO01838.1 - 0.087 12.7 1.3 0.17 11.7 0.2 1.9 1 1 1 2 2 2 0 SCIMP protein Spc7 PF08317.6 EOO01838.1 - 0.12 10.9 21.1 0.21 10.2 12.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 EOO01838.1 - 0.13 11.1 20.3 0.48 9.3 7.3 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EOO01838.1 - 0.19 10.9 10.1 0.57 9.3 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.6 EOO01838.1 - 0.3 10.8 22.0 2.4 7.9 3.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.9 EOO01838.1 - 0.34 10.8 16.9 0.22 11.4 4.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 EOO01838.1 - 0.5 10.6 7.0 2.7 8.3 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EOO01838.1 - 0.74 9.3 21.1 2.5 7.6 3.7 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EOO01838.1 - 0.8 9.4 12.9 1.3 8.7 1.2 2.8 2 1 1 3 3 3 0 Laminin Domain II Rootletin PF15035.1 EOO01838.1 - 0.91 9.4 21.5 0.8 9.6 10.3 2.6 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion DUF4613 PF15390.1 EOO01838.1 - 0.98 7.5 5.9 0.34 9.0 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) Effector_1 PF04518.7 EOO01838.1 - 1.2 8.0 5.3 4.1 6.2 0.5 2.2 2 0 0 2 2 2 0 Effector from type III secretion system SlyX PF04102.7 EOO01838.1 - 1.3 9.4 13.2 7.8 6.9 3.5 3.6 2 1 1 3 3 3 0 SlyX Mnd1 PF03962.10 EOO01838.1 - 1.6 8.3 20.4 0.84 9.2 6.4 2.5 1 1 1 2 2 2 0 Mnd1 family ERM PF00769.14 EOO01838.1 - 1.8 8.0 25.8 0.51 9.8 8.9 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 EOO01838.1 - 2.3 8.0 20.1 1.7 8.4 6.5 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EOO01838.1 - 4.3 7.2 6.8 14 5.6 0.3 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FemAB PF02388.11 EOO01838.1 - 4.7 5.7 14.4 0.24 10.0 1.4 2.4 1 1 0 2 2 2 0 FemAB family CENP-Q PF13094.1 EOO01838.1 - 4.7 7.2 29.9 6 6.8 18.9 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 EOO01838.1 - 5.1 6.2 24.7 3.7 6.6 4.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HAUS5 PF14817.1 EOO01838.1 - 5.4 5.4 19.7 37 2.6 13.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 GrpE PF01025.14 EOO01838.1 - 7.6 6.0 22.2 0.88 9.0 5.8 3.1 2 1 1 3 3 3 0 GrpE MerR-DNA-bind PF09278.6 EOO01838.1 - 7.8 6.9 15.8 5.1 7.5 0.8 3.4 2 2 0 2 2 2 0 MerR, DNA binding YlqD PF11068.3 EOO01838.1 - 8.7 6.3 19.8 0.95 9.5 4.8 2.8 3 0 0 3 3 3 0 YlqD protein DUF4201 PF13870.1 EOO01838.1 - 9.7 5.5 20.1 2.7 7.3 1.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) PA PF02225.17 EOO01839.1 - 3e-13 49.3 0.0 1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 PA domain Ribosomal_S4 PF00163.14 EOO01840.1 - 4.3e-29 100.7 1.1 9e-29 99.7 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EOO01840.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.6 3 0 0 3 3 3 1 S4 domain SBP_bac_11 PF13531.1 EOO01842.1 - 0.0052 16.4 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein MFS_1 PF07690.11 EOO01844.1 - 3.4e-34 118.1 32.0 3.6e-26 91.7 6.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO01844.1 - 6.1e-13 48.1 8.6 6.1e-13 48.1 6.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2207 PF09972.4 EOO01844.1 - 3.1 6.2 8.1 2.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_S7 PF00949.16 EOO01846.1 - 0.015 14.7 0.1 0.031 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease HMGL-like PF00682.14 EOO01847.1 - 1.5e-17 64.0 0.0 1.4e-15 57.6 0.0 2.2 1 1 0 1 1 1 1 HMGL-like Cupin_2 PF07883.6 EOO01848.1 - 9.2e-15 53.9 0.6 1.5e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EOO01848.1 - 0.00014 21.1 0.1 0.0056 16.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EOO01848.1 - 0.00054 19.6 0.3 0.0019 17.8 0.1 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain DUF1255 PF06865.6 EOO01848.1 - 0.015 15.5 0.0 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1255) Cupin_4 PF08007.7 EOO01848.1 - 0.079 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Ribosomal_L37e PF01907.14 EOO01849.1 - 1e-27 95.6 13.0 1.5e-27 95.1 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EOO01849.1 - 0.0016 18.1 1.9 0.0025 17.6 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EOO01849.1 - 0.0087 15.2 0.6 0.015 14.4 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EOO01849.1 - 0.27 10.7 3.9 3.1 7.3 2.8 2.1 1 1 1 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EOO01849.1 - 0.37 10.7 4.9 17 5.4 3.4 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4 PF00097.20 EOO01849.1 - 1.8 8.2 5.8 3 7.5 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 EOO01849.1 - 5.7 6.4 11.6 2.3 7.6 0.4 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 EOO01849.1 - 6 6.5 11.9 9.6 5.8 0.6 2.3 1 1 1 2 2 2 0 Ribosomal L40e family BBE PF08031.7 EOO01850.1 - 1.9e-05 24.4 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EOO01850.1 - 0.05 12.7 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_3 PF01494.14 EOO01851.1 - 2e-19 69.8 0.0 4.3e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO01851.1 - 1.2e-11 44.1 1.8 1.8e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO01851.1 - 3.9e-06 25.9 2.9 5.9e-06 25.3 2.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EOO01851.1 - 8.5e-06 26.0 0.3 0.0045 17.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO01851.1 - 2.4e-05 24.2 0.3 0.00011 22.0 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO01851.1 - 5.9e-05 22.3 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO01851.1 - 0.00012 20.7 0.9 0.00099 17.6 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EOO01851.1 - 0.00013 21.9 0.4 0.00037 20.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EOO01851.1 - 0.00022 20.2 0.1 0.0011 17.9 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.5 EOO01851.1 - 0.0048 15.7 0.0 0.018 13.8 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 EOO01851.1 - 0.0091 15.1 0.7 0.014 14.5 0.5 1.2 1 0 0 1 1 1 1 Thi4 family SnAC PF14619.1 EOO01851.1 - 0.041 14.0 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Pyr_redox_3 PF13738.1 EOO01851.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO01851.1 - 0.11 11.3 0.4 0.33 9.8 0.3 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EOO01851.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GST_N_3 PF13417.1 EOO01852.1 - 2.7e-17 62.7 0.0 3.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EOO01852.1 - 5e-17 61.8 0.0 6.6e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EOO01852.1 - 1e-13 51.0 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lipase_GDSL PF00657.17 EOO01853.1 - 1.2e-18 67.8 0.2 1.7e-18 67.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EOO01853.1 - 1.7e-14 54.3 0.1 3.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EOO01853.1 - 0.004 16.9 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Sensor_TM1 PF13755.1 EOO01854.1 - 0.14 11.6 1.3 0.56 9.7 0.1 2.1 1 1 1 2 2 2 0 Sensor N-terminal transmembrane domain OAD_gamma PF04277.8 EOO01854.1 - 0.2 12.0 1.4 0.23 11.8 0.1 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ATP-synt_DE PF00401.15 EOO01854.1 - 0.2 11.5 12.1 0.35 10.7 8.4 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF718 PF05336.8 EOO01855.1 - 1.2e-34 118.2 0.2 1.8e-34 117.6 0.1 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF718) DUF1295 PF06966.7 EOO01856.1 - 1.1e-11 44.5 0.2 1.6e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EOO01856.1 - 6.9e-06 24.8 1.0 1.1e-05 24.1 0.7 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 EOO01856.1 - 0.0016 18.2 0.3 0.0024 17.6 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase IncA PF04156.9 EOO01857.1 - 7.5e-07 28.9 35.3 0.00036 20.1 2.9 3.8 2 1 2 4 4 4 4 IncA protein Myosin_tail_1 PF01576.14 EOO01857.1 - 3 5.4 48.5 0.17 9.6 12.6 3.3 2 1 1 3 3 3 0 Myosin tail UPF0253 PF06786.7 EOO01858.1 - 0.1 12.7 0.3 15 5.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Ribosomal_L21e PF01157.13 EOO01859.1 - 4.3e-40 135.5 4.7 4.3e-40 135.5 3.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Aminotran_4 PF01063.14 EOO01862.1 - 7.5e-32 110.6 0.0 9.5e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Sec6 PF06046.8 EOO01863.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 Aldo_ket_red PF00248.16 EOO01864.1 - 8.5e-30 103.5 0.0 9.7e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.18 EOO01865.1 - 2.5e-17 63.2 2.0 3.2e-17 62.8 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region adh_short PF00106.20 EOO01867.1 - 2e-27 96.1 0.3 2.8e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01867.1 - 1.1e-22 80.9 0.0 1.4e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO01867.1 - 1.1e-13 51.2 0.1 1.6e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EOO01867.1 - 0.0015 18.1 1.2 0.69 9.4 0.3 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 EOO01867.1 - 0.028 13.5 0.5 0.05 12.6 0.3 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.6 EOO01867.1 - 0.082 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) HSP70 PF00012.15 EOO01868.1 - 1.3e-61 208.2 7.1 3.7e-59 200.2 0.0 3.5 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.8 EOO01868.1 - 0.0012 17.5 0.1 0.0038 15.8 0.1 1.8 1 0 0 1 1 1 1 MreB/Mbl protein Herpes_capsid PF06112.6 EOO01868.1 - 1.9 8.5 20.4 1.4 8.9 1.5 3.1 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein TcdB_toxin_midN PF12256.3 EOO01869.1 - 3.9e-15 55.7 5.5 1.2e-09 37.8 0.3 5.8 5 0 0 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region RHS_repeat PF05593.9 EOO01869.1 - 7.6e-09 35.5 40.7 0.22 11.7 0.1 13.7 13 2 0 14 14 14 4 RHS Repeat VCBS PF13517.1 EOO01869.1 - 9.4e-08 32.2 11.7 0.019 15.3 0.0 5.2 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO01869.1 - 5.7e-05 22.6 2.1 0.01 15.5 0.1 3.3 2 0 0 2 2 2 2 FG-GAP repeat SpvB PF03534.8 EOO01869.1 - 0.00011 21.3 0.4 0.44 9.5 0.1 2.5 2 0 0 2 2 2 2 Salmonella virulence plasmid 65kDa B protein Asp PF00026.18 EOO01870.1 - 3.9e-66 223.4 0.2 4.5e-66 223.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EOO01870.1 - 2.9e-06 27.6 0.2 0.0016 18.8 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EOO01870.1 - 0.00052 19.5 0.0 0.0023 17.4 0.0 2.1 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EOO01870.1 - 0.00074 19.4 0.0 0.0035 17.3 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal B1 PF02246.10 EOO01870.1 - 0.14 11.9 0.6 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein L b1 domain ERG4_ERG24 PF01222.12 EOO01871.1 - 6.2e-112 374.2 20.4 1.1e-72 244.9 6.1 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Beta-lactamase PF00144.19 EOO01872.1 - 5.6e-47 160.3 0.0 6.9e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Alpha-amylase PF00128.19 EOO01873.1 - 2.5e-29 102.7 0.0 4.3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Aconitase PF00330.15 EOO01874.1 - 7e-64 216.0 0.2 7.3e-41 140.1 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EOO01874.1 - 1.4e-16 60.7 0.0 3.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain AIP3 PF03915.8 EOO01875.1 - 5e-164 546.2 8.8 5e-164 546.2 6.1 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 EOO01875.1 - 0.003 16.9 0.5 0.003 16.9 0.4 3.1 4 0 0 4 4 4 1 Hepatic lectin, N-terminal domain FliL PF03748.9 EOO01875.1 - 0.014 15.3 0.2 0.077 12.9 0.1 2.3 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Thymidylat_synt PF00303.14 EOO01875.1 - 0.031 13.2 2.0 0.042 12.8 0.0 2.1 2 1 0 3 3 3 0 Thymidylate synthase GNVR PF13807.1 EOO01875.1 - 0.25 11.1 1.5 2 8.1 0.1 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF3138 PF11336.3 EOO01875.1 - 0.46 8.6 1.2 0.66 8.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Syntaxin_2 PF14523.1 EOO01875.1 - 1.9 8.5 0.0 1.9 8.5 0.0 4.4 4 1 1 5 5 5 0 Syntaxin-like protein MFS_1 PF07690.11 EOO01877.1 - 4.4e-34 117.7 36.8 6.6e-34 117.1 25.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CSL PF05207.8 EOO01878.1 - 1.3e-24 85.4 1.5 1.6e-24 85.1 1.0 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EOO01878.1 - 0.0038 17.1 0.3 0.0078 16.1 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EOO01878.1 - 0.11 11.8 0.4 0.25 10.7 0.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Glyco_hydro_31 PF01055.21 EOO01879.1 - 5.5e-127 424.2 0.7 6.9e-127 423.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EOO01879.1 - 2.1e-05 24.2 0.3 0.00011 22.0 0.0 2.4 3 0 0 3 3 3 1 Galactose mutarotase-like A_deaminase PF00962.17 EOO01880.1 - 6.2e-25 87.8 0.0 6.9e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cluap1 PF10234.4 EOO01881.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF16 PF01519.11 EOO01881.1 - 0.04 14.1 0.4 0.04 14.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DASH_Spc34 PF08657.5 EOO01881.1 - 0.043 13.4 0.4 0.043 13.4 0.3 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 Sipho_Gp157 PF05565.6 EOO01881.1 - 0.37 10.3 3.3 0.24 10.9 0.8 1.6 2 0 0 2 2 2 0 Siphovirus Gp157 Striatin PF08232.7 EOO01881.1 - 0.44 10.8 8.9 0.12 12.6 0.7 2.2 2 0 0 2 2 2 0 Striatin family ADIP PF11559.3 EOO01881.1 - 0.65 9.8 7.8 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BAF1_ABF1 PF04684.8 EOO01881.1 - 0.74 8.5 16.0 1.4 7.6 11.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EOO01881.1 - 1.4 7.1 28.6 2.1 6.4 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF241 PF03087.9 EOO01881.1 - 1.4 8.3 8.1 0.12 11.7 1.3 1.9 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF605 PF04652.11 EOO01881.1 - 1.7 7.9 27.0 2 7.7 18.7 1.1 1 0 0 1 1 1 0 Vta1 like CENP-Q PF13094.1 EOO01881.1 - 8.3 6.4 16.0 0.64 10.0 3.1 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Aldo_ket_red PF00248.16 EOO01882.1 - 9.6e-70 234.6 0.0 1.1e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SGL PF08450.7 EOO01883.1 - 4.4e-24 85.2 1.2 1.5e-23 83.4 0.8 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EOO01883.1 - 5.4e-05 23.0 0.0 0.0015 18.4 0.0 2.6 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.11 EOO01883.1 - 0.00018 21.4 0.0 0.00083 19.3 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase LsmAD PF06741.8 EOO01885.1 - 2.9e-21 75.3 2.5 2.9e-21 75.3 1.7 2.3 3 0 0 3 3 3 1 LsmAD domain AA_permease PF00324.16 EOO01887.1 - 1.8e-69 234.3 27.4 2.2e-69 234.0 19.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO01887.1 - 4.4e-19 68.3 30.6 5.5e-19 68.0 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EOO01887.1 - 0.24 11.1 6.9 0.17 11.6 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Synaptobrevin PF00957.16 EOO01887.1 - 0.33 10.5 0.1 0.33 10.5 0.0 2.7 3 0 0 3 3 3 0 Synaptobrevin DUF3397 PF11877.3 EOO01887.1 - 1.8 8.5 0.0 1.8 8.5 0.0 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3397) PrgI PF12666.2 EOO01887.1 - 6.2 7.0 12.7 0.34 11.0 0.6 2.9 3 0 0 3 3 3 0 PrgI family protein FAD_binding_3 PF01494.14 EOO01888.1 - 9.7e-21 74.1 0.1 3.6e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EOO01888.1 - 0.00035 19.4 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 EOO01888.1 - 0.00061 18.7 0.0 0.002 17.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO01888.1 - 0.0016 18.3 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EOO01888.1 - 0.0056 15.1 0.0 0.011 14.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EOO01888.1 - 0.0078 16.1 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO01888.1 - 0.0097 16.2 0.1 0.08 13.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CP_ATPgrasp_1 PF04174.8 EOO01888.1 - 0.01 14.4 0.1 0.12 11.0 0.0 2.0 2 0 0 2 2 2 0 A circularly permuted ATPgrasp Trp_halogenase PF04820.9 EOO01888.1 - 0.034 12.7 0.0 0.072 11.7 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 EOO01888.1 - 0.039 13.3 0.1 0.15 11.4 0.0 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EOO01888.1 - 0.039 12.8 0.2 0.3 9.9 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EOO01888.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 EOO01889.1 - 1e-59 202.0 0.0 1.4e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO01889.1 - 2.6e-06 27.2 9.0 4.9e-06 26.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_4 PF13418.1 EOO01890.1 - 2.4e-21 75.2 4.7 1.4e-06 27.9 0.0 3.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EOO01890.1 - 1.8e-19 69.3 2.8 2.3e-08 33.9 0.1 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EOO01890.1 - 8.9e-19 66.7 1.5 1.8e-08 33.7 0.4 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EOO01890.1 - 1.5e-17 63.0 1.2 0.00014 21.6 0.1 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EOO01890.1 - 7.7e-17 60.6 2.6 5.2e-09 35.8 0.7 3.3 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EOO01890.1 - 1.8e-14 52.8 2.2 5.1e-06 26.0 0.6 3.5 3 0 0 3 3 3 3 Kelch motif DUF904 PF06005.7 EOO01890.1 - 9.7 6.5 30.7 0.044 14.0 4.4 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF904) Raptor_N PF14538.1 EOO01891.1 - 2.1e-64 216.0 0.0 3e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain tRNA-synt_2 PF00152.15 EOO01892.1 - 1.9e-14 53.2 0.0 3.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EOO01892.1 - 0.00069 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PhoU PF01895.14 EOO01892.1 - 0.86 10.0 4.2 0.19 12.2 0.3 1.7 2 0 0 2 2 2 0 PhoU domain WD40 PF00400.27 EOO01893.1 - 0.00012 21.8 0.3 0.039 13.8 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 EOO01893.1 - 0.0073 14.5 0.0 0.0078 14.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FA_desaturase PF00487.19 EOO01894.1 - 2.6e-33 115.5 21.4 3.4e-33 115.1 14.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EOO01894.1 - 8.6e-20 69.7 0.2 1.8e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HhH-GPD PF00730.20 EOO01895.1 - 6.3e-17 61.8 0.0 4.3e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF2051 PF09738.4 EOO01896.1 - 4.7e-05 22.8 7.5 4.7e-05 22.8 5.2 1.8 2 1 0 2 2 2 1 Double stranded RNA binding protein (DUF2051) DUF4646 PF15496.1 EOO01896.1 - 9.4e-05 22.4 0.2 0.0003 20.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 EOO01896.1 - 0.0016 17.8 18.2 0.0016 17.8 12.6 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nucleopor_Nup85 PF07575.8 EOO01897.1 - 1.8e-05 23.2 0.1 0.00028 19.2 0.0 2.3 2 1 0 2 2 2 1 Nup85 Nucleoporin UPF0253 PF06786.7 EOO01897.1 - 0.11 12.6 0.8 1.5 8.9 0.3 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Nucleoplasmin PF03066.10 EOO01897.1 - 0.5 9.8 6.9 0.71 9.3 3.7 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EOO01897.1 - 2.9 8.2 15.7 0.042 14.1 5.1 2.3 1 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.7 EOO01898.1 - 3.7e-08 33.7 0.0 5.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO01898.1 - 6.6e-06 25.9 0.0 9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO01898.1 - 7.6e-05 23.1 0.0 9.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO01898.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Herpes_LP PF03363.8 EOO01898.1 - 0.0053 16.3 3.6 0.0071 15.9 2.5 1.2 1 0 0 1 1 1 1 Herpesvirus leader protein Ubie_methyltran PF01209.13 EOO01898.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family G-patch PF01585.18 EOO01899.1 - 1.9e-11 43.5 1.8 2.2e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 EOO01899.1 - 6e-06 26.0 0.1 1.1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EOO01899.1 - 0.0025 17.4 0.1 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO01899.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 EOO01899.1 - 4.6 5.8 5.5 8 5.0 3.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Amino_oxidase PF01593.19 EOO01900.1 - 9.3e-52 176.5 0.0 2.7e-51 175.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EOO01900.1 - 8.6e-14 51.3 0.4 1.7e-13 50.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO01900.1 - 6.3e-09 35.2 0.0 1.2e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO01900.1 - 4.2e-07 30.2 0.1 0.00036 20.6 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO01900.1 - 1e-06 28.1 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO01900.1 - 3.7e-06 26.0 1.4 5.4e-06 25.5 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EOO01900.1 - 1.1e-05 25.7 0.2 2.8e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO01900.1 - 2.1e-05 23.1 0.2 4.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EOO01900.1 - 0.00018 20.7 0.1 0.00028 20.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EOO01900.1 - 0.00028 20.0 0.1 0.00045 19.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EOO01900.1 - 0.001 18.0 0.3 0.0018 17.2 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EOO01900.1 - 0.003 17.4 0.2 0.009 15.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO01900.1 - 0.0078 15.1 0.1 0.016 14.1 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Ecm33 PF12454.3 EOO01901.1 - 2.7e-12 46.3 5.7 8e-12 44.8 3.9 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EOO01901.1 - 3.4e-05 23.7 1.8 0.86 9.5 0.0 4.5 1 1 4 5 5 5 2 Receptor L domain DUF4522 PF15022.1 EOO01901.1 - 0.0047 16.6 0.0 0.83 9.3 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4522) LRR_5 PF13306.1 EOO01901.1 - 0.006 16.2 3.1 0.23 11.1 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EOO01901.1 - 0.054 13.2 0.3 0.054 13.2 0.2 2.8 2 0 0 2 2 2 0 Leucine rich repeat Aldo_ket_red PF00248.16 EOO01902.1 - 8.4e-41 139.6 0.0 9.6e-40 136.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Amino_oxidase PF01593.19 EOO01903.1 - 6.2e-48 163.9 0.0 7.2e-27 94.5 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase IF-2B PF01008.12 EOO01903.1 - 1.8e-42 145.2 0.0 5e-42 143.8 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NAD_binding_8 PF13450.1 EOO01903.1 - 2.6e-13 49.7 1.5 6.2e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EOO01903.1 - 3.6e-05 23.9 0.4 0.0001 22.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO01903.1 - 0.0012 17.9 0.0 0.0032 16.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EOO01903.1 - 0.0017 18.7 1.7 0.0027 18.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO01903.1 - 0.0029 16.5 0.4 0.0085 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase XdhC_C PF13478.1 EOO01903.1 - 0.0048 17.2 0.9 1.7 8.9 0.0 3.1 3 1 0 3 3 3 1 XdhC Rossmann domain NAD_binding_9 PF13454.1 EOO01903.1 - 0.012 15.3 0.4 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EOO01903.1 - 0.018 13.9 0.1 0.018 13.9 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EOO01903.1 - 0.03 12.8 0.3 0.11 10.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EOO01903.1 - 0.031 13.3 0.5 0.057 12.4 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EOO01903.1 - 0.059 13.0 0.1 0.22 11.1 0.1 2.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EOO01903.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 EOO01904.1 - 5.9e-70 235.3 0.1 6.6e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_15 PF00723.16 EOO01904.1 - 0.05 12.1 0.0 0.089 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DUF1498 PF07385.7 EOO01904.1 - 0.12 11.4 0.1 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) Acetyltransf_1 PF00583.19 EOO01905.1 - 3e-16 59.2 0.1 6.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EOO01905.1 - 2.1e-07 30.6 0.1 3.7e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EOO01905.1 - 3.1e-06 27.2 0.2 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EOO01905.1 - 0.0022 18.1 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EOO01905.1 - 0.005 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EOO01905.1 - 0.047 13.8 0.0 0.09 12.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EOO01905.1 - 0.051 13.5 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EOO01905.1 - 0.12 12.0 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase zf-CCHC PF00098.18 EOO01906.1 - 2.6e-62 203.9 118.5 1.3e-06 28.0 0.9 13.6 13 1 0 13 13 13 12 Zinc knuckle zf-CCHC_2 PF13696.1 EOO01906.1 - 1.4e-08 34.1 69.9 0.0049 16.3 0.6 12.7 7 2 6 13 13 13 8 Zinc knuckle zf-CCHC_4 PF14392.1 EOO01906.1 - 2.1e-08 33.6 79.6 0.15 11.7 0.1 12.4 12 0 0 12 12 12 10 Zinc knuckle zf-CCHC_3 PF13917.1 EOO01906.1 - 0.0019 17.8 88.0 0.1 12.3 0.4 12.0 4 4 8 12 12 12 9 Zinc knuckle AMP-binding PF00501.23 EOO01907.1 - 8.1e-86 287.9 0.0 9.6e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO01907.1 - 1.5e-14 54.7 0.0 3.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EOO01907.1 - 0.0013 17.4 0.0 0.02 13.4 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.9 EOO01908.1 - 1.1e-08 35.1 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Acyl-CoA_dh_1 PF00441.19 EOO01909.1 - 1.2e-32 113.0 0.3 2.1e-32 112.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EOO01909.1 - 4.6e-20 71.1 0.0 1e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EOO01909.1 - 3.6e-15 55.2 0.3 6.8e-15 54.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EOO01909.1 - 3.3e-07 30.8 0.0 7.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EOO01909.1 - 0.0062 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF952 PF06108.7 EOO01910.1 - 4.3e-21 74.5 0.0 5.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) UCH PF00443.24 EOO01911.1 - 5.5e-44 150.3 0.0 1.2e-43 149.1 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EOO01911.1 - 1.8e-12 47.2 0.0 2.7e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2408 PF10303.4 EOO01912.1 - 2.6e-49 166.7 3.6 4.1e-29 101.3 0.0 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) TMF_TATA_bd PF12325.3 EOO01912.1 - 0.045 13.4 1.7 0.081 12.6 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EOO01912.1 - 0.14 11.9 0.6 1.5 8.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EOO01912.1 - 0.19 11.9 3.5 21 5.4 0.0 4.5 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein CorA PF01544.13 EOO01912.1 - 0.62 9.0 3.6 0.42 9.5 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Anp1 PF03452.9 EOO01913.1 - 1.9e-108 361.7 0.2 2.2e-108 361.4 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EOO01913.1 - 6.7e-05 22.6 0.4 0.11 12.1 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 WD40 PF00400.27 EOO01914.1 - 6.5e-29 98.7 5.3 2.6e-09 36.6 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Motile_Sperm PF00635.21 EOO01915.1 - 9.4e-24 83.1 0.3 1.6e-23 82.4 0.2 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EOO01915.1 - 0.056 13.5 0.1 0.26 11.3 0.0 2.0 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBX PF00789.15 EOO01916.1 - 8.7e-06 25.7 0.0 2.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EOO01916.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 EOO01916.1 - 0.0044 17.0 0.2 0.0099 15.9 0.1 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NOZZLE PF08744.5 EOO01916.1 - 0.05 12.9 1.3 0.071 12.4 0.9 1.3 1 0 0 1 1 1 0 Plant transcription factor NOZZLE zf-C2H2 PF00096.21 EOO01916.1 - 0.1 12.9 0.4 0.23 11.9 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.1 EOO01916.1 - 0.73 10.1 6.0 0.88 9.8 4.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein APG6 PF04111.7 EOO01916.1 - 4.6 6.1 26.0 8.1 5.3 18.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 adh_short PF00106.20 EOO01917.1 - 1.1e-12 48.2 0.3 2.1e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01917.1 - 0.0009 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO01917.1 - 0.0066 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO01917.1 - 0.074 13.0 0.5 0.22 11.5 0.2 1.9 2 1 0 2 2 2 0 NADH(P)-binding UCR_14kD PF02271.11 EOO01918.1 - 6.9e-44 147.9 0.2 7.9e-44 147.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit adh_short PF00106.20 EOO01919.1 - 5.5e-30 104.4 0.3 7.6e-30 104.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01919.1 - 6.2e-25 88.3 0.6 1.5e-23 83.8 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO01919.1 - 1.6e-13 50.6 0.1 2.2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO01919.1 - 9.7e-07 28.4 0.1 5.4e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AhpC-TSA PF00578.16 EOO01920.1 - 6.9e-26 90.3 0.0 9.8e-26 89.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EOO01920.1 - 4.8e-15 55.3 0.0 6.8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EOO01920.1 - 0.0017 18.2 0.0 0.0085 16.0 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme zf-CCHC PF00098.18 EOO01922.1 - 4.2e-29 99.0 30.9 1.3e-09 37.5 2.3 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EOO01922.1 - 5.7e-06 25.9 20.9 0.046 13.3 0.7 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 EOO01922.1 - 3.4e-05 23.4 21.1 0.12 12.0 0.3 4.1 2 1 2 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EOO01922.1 - 0.00045 19.6 20.1 0.0089 15.4 0.4 4.2 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 EOO01922.1 - 0.076 12.6 1.2 0.076 12.6 0.8 3.9 3 1 1 4 4 4 0 Zinc knuckle Ribosomal_60s PF00428.14 EOO01923.1 - 9.4e-26 90.0 13.9 1.1e-25 89.7 9.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jun PF03957.8 EOO01923.1 - 0.039 13.6 1.0 0.043 13.5 0.7 1.1 1 0 0 1 1 1 0 Jun-like transcription factor OCC1 PF15506.1 EOO01923.1 - 7.9 6.4 8.1 16 5.4 5.6 1.5 1 0 0 1 1 1 0 OCC1 family Membr_traf_MHD PF10540.4 EOO01924.1 - 1.2e-22 80.1 0.6 4e-22 78.4 0.2 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EOO01924.1 - 2.1e-17 62.7 0.1 5.2e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain 4HBT_3 PF13622.1 EOO01924.1 - 1.3e-16 61.1 0.0 3.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF810 PF05664.6 EOO01924.1 - 1.5e-07 30.1 0.3 2.5e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Rep_N PF08724.5 EOO01924.1 - 0.057 12.9 0.2 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Rep protein catalytic domain like 4HBT PF03061.17 EOO01924.1 - 0.097 12.8 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 Thioesterase superfamily GTP_EFTU PF00009.22 EOO01926.1 - 6.4e-38 130.0 0.0 1.1e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EOO01926.1 - 1.6e-36 124.1 0.4 3.3e-36 123.1 0.3 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EOO01926.1 - 1.6e-10 40.9 0.2 3.4e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EOO01926.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EOO01926.1 - 0.11 12.3 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Dynamin family EMP24_GP25L PF01105.19 EOO01927.1 - 0.049 13.3 4.6 0.42 10.3 2.2 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin_2 PF14523.1 EOO01927.1 - 1.2 9.1 7.1 2.6 8.1 0.5 3.1 2 1 0 2 2 2 0 Syntaxin-like protein Pkinase PF00069.20 EOO01928.1 - 3.7e-77 258.9 0.1 6.3e-77 258.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO01928.1 - 3.5e-39 134.4 0.0 5.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EOO01928.1 - 6.6e-17 61.3 0.4 1.7e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EOO01928.1 - 2.1e-10 40.0 0.0 3.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EOO01928.1 - 0.00063 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EOO01928.1 - 0.016 14.9 0.0 0.061 13.0 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EOO01928.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EOO01928.1 - 0.023 13.5 0.1 0.041 12.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EOO01928.1 - 0.19 11.0 1.4 0.36 10.1 0.2 1.9 2 1 1 3 3 3 0 RIO1 family ADK PF00406.17 EOO01930.1 - 5.8e-45 152.8 0.0 9.8e-45 152.1 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EOO01930.1 - 5.5e-08 33.1 0.0 8.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EOO01930.1 - 2.1e-06 28.5 0.0 3.2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EOO01930.1 - 2.9e-05 23.9 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EOO01930.1 - 5.2e-05 22.7 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase MRP_L53 PF10780.4 EOO01932.1 - 1.9e-19 69.3 0.7 1.9e-19 69.3 0.5 1.5 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.8 EOO01932.1 - 0.06 13.0 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Ecotin Pyrophosphatase PF00719.14 EOO01933.1 - 4.9e-52 175.5 0.2 6.3e-52 175.1 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PfkB PF00294.19 EOO01934.1 - 2.9e-18 66.0 0.2 4.3e-16 58.9 0.2 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Sec20 PF03908.8 EOO01935.1 - 1.8e-14 53.1 2.4 1.8e-14 53.1 0.4 1.9 2 0 0 2 2 2 1 Sec20 DUF2353 PF09789.4 EOO01935.1 - 0.015 14.5 0.9 0.015 14.5 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Med30 PF11315.3 EOO01935.1 - 0.097 12.8 3.3 0.37 10.9 0.2 2.6 2 0 0 2 2 2 0 Mediator complex subunit 30 Syntaxin PF00804.20 EOO01935.1 - 0.11 12.6 4.0 0.15 12.2 0.5 2.4 2 0 0 2 2 2 0 Syntaxin CCDC32 PF14989.1 EOO01935.1 - 0.31 10.8 7.0 3.3 7.5 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Hrs_helical PF12210.3 EOO01935.1 - 0.55 10.5 3.4 8 6.7 0.1 3.1 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Syntaxin-6_N PF09177.6 EOO01935.1 - 2.9 8.3 5.7 13 6.2 1.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.10 EOO01935.1 - 3.1 6.9 9.3 1.4 8.0 0.9 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Indigoidine_A PF04227.7 EOO01936.1 - 3e-107 358.2 0.9 3.5e-107 357.9 0.6 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein PCI PF01399.22 EOO01937.1 - 2e-12 47.3 0.2 4.8e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 PCI domain DUF202 PF02656.10 EOO01938.1 - 0.0048 17.0 5.5 0.0097 16.1 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF3329 PF11808.3 EOO01938.1 - 0.03 14.3 0.1 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Tetraspannin PF00335.15 EOO01938.1 - 0.11 11.8 7.2 0.21 10.8 5.0 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF4064 PF13273.1 EOO01938.1 - 0.3 11.1 2.4 0.59 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) COX1 PF00115.15 EOO01938.1 - 0.71 8.4 7.1 0.068 11.7 1.9 1.3 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I MARVEL PF01284.18 EOO01938.1 - 2 8.2 11.1 2.8 7.7 7.0 1.8 1 1 1 2 2 2 0 Membrane-associating domain WD40 PF00400.27 EOO01940.1 - 8.7e-10 38.1 0.6 0.022 14.6 0.3 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 EOO01940.1 - 0.0087 15.7 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EOO01940.1 - 0.12 11.8 0.0 24 4.5 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NmrA PF05368.8 EOO01942.1 - 3.7e-60 203.0 0.0 4.7e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01942.1 - 2.7e-15 56.8 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EOO01942.1 - 1.5e-06 27.1 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DIOX_N PF14226.1 EOO01943.1 - 9.9e-26 90.5 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO01943.1 - 1.7e-21 76.3 0.0 3.8e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EOO01944.1 - 4.3e-29 101.3 24.2 4.3e-29 101.3 16.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-DHHC PF01529.15 EOO01944.1 - 0.31 10.4 5.9 0.093 12.1 0.4 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_88 PF07470.8 EOO01945.1 - 1.1e-79 267.9 1.4 1.2e-79 267.7 1.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 EOO01945.1 - 1.3 8.3 7.6 2 7.7 0.6 2.7 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 MatE PF01554.13 EOO01948.1 - 1.8e-48 164.2 25.5 1.4e-26 93.0 3.6 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EOO01948.1 - 7e-09 35.6 5.5 7e-09 35.6 3.8 4.1 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.11 EOO01949.1 - 8.8e-23 80.5 15.5 8.8e-23 80.5 10.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO01949.1 - 4.2e-13 48.6 0.6 5.1e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EOO01949.1 - 7.5e-06 24.3 3.7 9.8e-06 23.9 2.5 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.1 EOO01949.1 - 0.0015 16.9 4.4 0.0015 16.9 3.0 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 EOO01949.1 - 0.0049 15.1 3.1 0.0064 14.7 2.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EOO01949.1 - 0.021 13.4 1.1 0.031 12.8 0.8 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter DUF4131 PF13567.1 EOO01949.1 - 5.3 6.4 8.5 2.9 7.2 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Reo_sigmaC PF04582.7 EOO01950.1 - 0.94 8.5 28.8 0.68 9.0 0.4 4.5 2 1 3 6 6 6 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EOO01950.1 - 2.6 6.6 82.9 0.023 13.3 16.6 5.5 2 1 4 6 6 6 0 Spc7 kinetochore protein MFS_1 PF07690.11 EOO01951.1 - 1.3e-33 116.2 22.9 1.6e-33 115.9 15.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO01951.1 - 4.8e-14 51.7 3.5 4.8e-14 51.7 2.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EOO01951.1 - 2.2e-05 22.8 4.2 3.1e-05 22.3 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NmrA PF05368.8 EOO01952.1 - 4.2e-25 88.3 0.0 5.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO01952.1 - 3.8e-12 46.5 0.0 4.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EOO01952.1 - 1.5e-10 40.5 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EOO01952.1 - 7.5e-05 22.8 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EOO01952.1 - 0.00021 20.8 0.2 0.00069 19.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EOO01952.1 - 0.00064 19.6 0.1 0.0013 18.6 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EOO01952.1 - 0.0073 15.0 0.1 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 EOO01952.1 - 0.011 15.5 3.0 1.2 8.9 0.0 2.5 1 1 1 2 2 2 0 ThiF family NAD_binding_4 PF07993.7 EOO01952.1 - 0.015 14.2 0.1 0.073 11.9 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EOO01952.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EOO01952.1 - 0.022 15.0 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EOO01952.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 EOO01953.1 - 5.5e-14 52.4 0.1 2.7e-13 50.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO01953.1 - 1.8e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EOO01953.1 - 3.6e-06 27.1 0.1 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EOO01953.1 - 0.00011 21.4 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EOO01953.1 - 0.00093 18.6 0.0 0.0082 15.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO01953.1 - 0.053 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.8 EOO01953.1 - 0.058 12.0 0.2 0.091 11.3 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase F420_oxidored PF03807.12 EOO01953.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Arginase PF00491.16 EOO01954.1 - 4.2e-89 298.5 0.0 5.2e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EOO01954.1 - 0.064 13.4 0.2 0.18 12.0 0.0 1.7 1 1 1 2 2 2 0 UPF0489 domain Sugar_tr PF00083.19 EOO01955.1 - 1.3e-66 225.0 26.0 1.5e-66 224.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO01955.1 - 8.2e-08 31.3 35.3 8.2e-08 31.3 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO01955.1 - 0.0078 14.6 27.6 0.011 14.1 6.8 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein nlz1 PF12402.3 EOO01956.1 - 0.034 14.4 0.1 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 Transp_cyt_pur PF02133.10 EOO01957.1 - 1.5e-25 89.6 33.6 2.2e-25 89.0 23.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_4 PF08386.5 EOO01958.1 - 1.3e-20 73.2 0.0 2.4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EOO01958.1 - 4.3e-09 36.5 0.6 0.00058 19.8 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO01958.1 - 2e-07 30.7 0.6 2.1e-06 27.4 0.3 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.17 EOO01959.1 - 3e-08 33.2 0.0 3.6e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3 PF00933.16 EOO01960.1 - 1.2e-93 313.3 0.0 1.7e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO01960.1 - 7.7e-59 198.9 0.0 8.4e-58 195.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO01960.1 - 9.7e-26 89.5 0.0 1.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Halo_GVPC PF05465.8 EOO01960.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat LA-virus_coat PF09220.5 EOO01961.1 - 0.069 11.5 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 L-A virus, major coat protein Abhydrolase_3 PF07859.8 EOO01962.1 - 2.9e-60 203.4 0.1 3.8e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EOO01962.1 - 6.6e-06 25.4 0.0 0.00019 20.7 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EOO01962.1 - 2.1e-05 23.4 0.0 3.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EOO01962.1 - 4e-05 22.9 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EOO01962.1 - 4.8e-05 23.1 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EOO01962.1 - 0.0021 16.6 0.0 0.0052 15.3 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Nrap PF03813.9 EOO01963.1 - 1.2e-142 476.6 0.0 1.3e-142 476.4 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DASH_Dam1 PF08653.5 EOO01964.1 - 3.2e-27 94.0 0.9 4.6e-27 93.5 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 BolA PF01722.13 EOO01965.1 - 2.4e-21 75.4 0.0 3e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein ASF1_hist_chap PF04729.8 EOO01966.1 - 2.5e-66 222.0 0.1 3.2e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.5 EOO01966.1 - 0.41 9.6 18.3 0.51 9.3 12.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EOO01966.1 - 4.9 4.9 21.7 6.6 4.5 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family Thi4 PF01946.12 EOO01967.1 - 3.7e-105 350.1 0.1 4.7e-105 349.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EOO01967.1 - 5.5e-07 28.8 1.3 1.7e-06 27.2 0.8 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EOO01967.1 - 1e-05 24.6 0.5 4.2e-05 22.6 0.3 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EOO01967.1 - 2.1e-05 24.4 0.3 5.2e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EOO01967.1 - 0.00014 20.8 2.0 0.0017 17.2 0.8 2.4 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EOO01967.1 - 0.00016 21.6 0.1 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO01967.1 - 0.00039 20.5 0.1 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO01967.1 - 0.00098 18.9 1.4 0.002 17.9 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EOO01967.1 - 0.0053 15.9 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO01967.1 - 0.016 13.6 0.8 0.024 13.1 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein CoA_trans PF01144.18 EOO01968.1 - 3.2e-98 327.2 0.5 1.6e-59 200.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mog1 PF04603.7 EOO01969.1 - 8.6e-18 64.6 0.0 1.6e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Cellulase PF00150.13 EOO01970.1 - 1.3e-11 44.2 2.9 2.6e-07 30.1 0.8 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EOO01970.1 - 0.0055 15.8 0.4 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase XFP_N PF09364.5 EOO01971.1 - 3.1e-177 588.8 0.0 4e-177 588.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EOO01971.1 - 1.4e-82 276.0 0.0 2.1e-82 275.4 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EOO01971.1 - 4.7e-82 273.9 0.0 1.3e-81 272.4 0.0 1.7 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase UCH PF00443.24 EOO01972.1 - 8.9e-36 123.3 0.0 6.6e-35 120.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EOO01972.1 - 3.4e-14 52.9 0.0 9.1e-09 35.1 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Med9 PF07544.8 EOO01973.1 - 1.1e-22 79.5 0.0 1.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 PEP-utilisers_N PF05524.8 EOO01973.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Gpi1 PF05024.10 EOO01974.1 - 2.5e-64 216.4 8.7 5.7e-64 215.2 6.0 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) GPI-anchored PF10342.4 EOO01974.1 - 1.1e-08 35.4 0.7 3.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Neurensin PF14927.1 EOO01974.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Neurensin DNA_pol3_delta PF06144.8 EOO01974.1 - 0.29 10.6 1.7 0.44 10.0 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ATP-synt_E PF05680.7 EOO01974.1 - 1.5 8.8 4.2 4 7.4 2.9 1.6 1 0 0 1 1 1 0 ATP synthase E chain iPGM_N PF06415.8 EOO01975.1 - 3.6e-74 248.8 0.0 4.8e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EOO01975.1 - 1.5e-71 240.7 0.0 1.8e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EOO01975.1 - 5.2e-07 29.3 0.0 1.6e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EOO01975.1 - 0.00012 21.4 0.0 0.00086 18.5 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 EOO01975.1 - 0.00095 18.5 0.0 0.0033 16.7 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Leucyl-specific PF14795.1 EOO01975.1 - 0.12 12.2 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain AMMECR1 PF01871.12 EOO01976.1 - 1.3e-43 148.1 0.0 8.8e-43 145.3 0.0 1.9 2 0 0 2 2 2 1 AMMECR1 PP28 PF10252.4 EOO01977.1 - 2.6e-27 94.6 17.1 2.6e-27 94.6 11.9 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 GP38 PF05268.6 EOO01977.1 - 0.4 10.0 4.7 0.54 9.6 3.3 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Daxx PF03344.10 EOO01977.1 - 4 5.8 31.0 6.4 5.1 21.5 1.3 1 0 0 1 1 1 0 Daxx Family Glyco_hydro_17 PF00332.13 EOO01978.1 - 2.2e-08 33.5 5.7 2.3e-07 30.1 0.3 2.3 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 DUF167 PF02594.11 EOO01979.1 - 4.2e-17 61.8 0.4 5.5e-17 61.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DJ-1_PfpI PF01965.19 EOO01980.1 - 2.8e-09 36.6 0.0 2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EOO01980.1 - 0.00012 21.3 0.0 0.00058 19.1 0.0 1.9 1 1 0 1 1 1 1 Putative amidotransferase Esterase_phd PF10503.4 EOO01981.1 - 0.015 14.5 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase TPR_11 PF13414.1 EOO01982.1 - 2.4e-48 161.6 40.8 8.5e-09 34.9 0.1 13.2 12 2 2 14 14 13 12 TPR repeat TPR_16 PF13432.1 EOO01982.1 - 1.1e-38 131.1 42.3 5.7e-08 33.2 0.6 12.6 9 3 3 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 EOO01982.1 - 6.1e-36 119.4 44.9 0.0071 16.1 0.1 16.8 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_19 PF14559.1 EOO01982.1 - 1.5e-35 121.3 27.1 7.4e-06 26.2 1.5 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.1 EOO01982.1 - 1.7e-32 108.9 35.5 0.0076 16.7 0.0 16.6 11 6 6 17 17 17 9 Tetratricopeptide repeat TPR_1 PF00515.23 EOO01982.1 - 6.4e-30 101.5 39.3 0.00083 18.8 0.0 15.9 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_12 PF13424.1 EOO01982.1 - 4.5e-28 96.9 38.7 1.6e-05 24.7 0.0 13.1 7 3 5 14 14 14 11 Tetratricopeptide repeat TPR_17 PF13431.1 EOO01982.1 - 1e-27 93.9 18.4 0.11 12.7 0.0 17.1 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_8 PF13181.1 EOO01982.1 - 3.2e-18 64.0 18.9 0.0072 16.0 0.0 13.3 13 1 1 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 EOO01982.1 - 4.1e-17 60.5 32.6 0.015 15.0 0.0 15.2 15 1 1 16 16 16 3 Tetratricopeptide repeat Apc3 PF12895.2 EOO01982.1 - 1.2e-11 44.5 23.4 9.4e-05 22.4 0.0 8.9 8 3 1 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EOO01982.1 - 5e-08 32.6 16.6 0.0073 16.1 1.0 8.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EOO01982.1 - 5.9e-07 29.5 28.8 0.59 10.7 0.1 13.9 17 0 0 17 17 14 1 Tetratricopeptide repeat TPR_10 PF13374.1 EOO01982.1 - 1.1e-05 25.2 14.3 1.9 8.5 0.0 7.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EOO01982.1 - 5.8e-05 23.1 14.2 1 9.5 0.2 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 EOO01982.1 - 7.5e-05 22.7 16.4 1.5 9.4 0.2 9.2 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF2225 PF09986.4 EOO01982.1 - 0.00017 21.1 0.4 0.9 8.9 0.2 3.7 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_WDAD PF04053.9 EOO01982.1 - 0.0093 14.8 0.1 0.035 12.8 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region HemY_N PF07219.8 EOO01982.1 - 0.011 15.2 2.6 24 4.5 0.0 4.9 4 1 1 5 5 5 0 HemY protein N-terminus ChAPs PF09295.5 EOO01982.1 - 0.022 13.5 0.7 10 4.7 0.0 3.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) IBR PF01485.16 EOO01983.1 - 2.3e-22 78.6 46.7 2e-12 46.7 4.2 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EOO01983.1 - 7.8e-06 25.4 43.3 0.00059 19.4 4.8 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO01983.1 - 4.4e-05 23.4 8.3 4.4e-05 23.4 5.8 4.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EOO01983.1 - 6.6e-05 22.6 43.5 0.001 18.8 5.4 3.6 2 1 1 3 3 3 3 Ring finger domain UN_NPL4 PF11543.3 EOO01983.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EOO01983.1 - 0.25 11.1 45.3 0.024 14.3 6.3 3.8 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EOO01983.1 - 1.4 8.8 35.4 0.16 11.8 2.1 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EOO01983.1 - 5.4 6.8 23.3 0.49 10.1 2.3 3.7 3 0 0 3 3 3 0 RING-type zinc-finger XPG_I PF00867.13 EOO01984.1 - 1.7e-25 88.8 0.0 4.1e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EOO01984.1 - 8.2e-19 67.7 0.0 1.8e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EOO01984.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing ATP-synt_C PF00137.16 EOO01985.1 - 3.2e-16 58.9 10.5 5.3e-16 58.2 7.3 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF367 PF04034.8 EOO01986.1 - 6e-48 161.6 0.1 8.7e-48 161.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EOO01986.1 - 5.7e-12 44.9 1.2 1.2e-11 43.9 0.8 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 EOO01986.1 - 0.034 12.6 25.3 0.045 12.2 17.5 1.0 1 0 0 1 1 1 0 Daxx Family TBCC PF07986.7 EOO01987.1 - 2.4e-33 114.1 0.1 4.5e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C SprT-like PF10263.4 EOO01988.1 - 2.2e-51 173.6 5.1 3e-51 173.1 3.5 1.2 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EOO01988.1 - 0.014 15.6 0.2 0.014 15.6 0.1 2.2 3 0 0 3 3 3 0 HMG (high mobility group) box Peptidase_MA_2 PF13485.1 EOO01988.1 - 0.099 12.6 0.5 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Lyase_1 PF00206.15 EOO01988.1 - 0.13 11.3 1.5 0.11 11.7 0.1 1.5 2 0 0 2 2 2 0 Lyase DUF155 PF02582.9 EOO01989.1 - 1.3e-42 145.6 0.0 1.9e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 EOO01989.1 - 0.028 13.7 0.0 0.075 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Redoxin PF08534.5 EOO01990.1 - 1.7e-28 98.9 0.0 2.1e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF1767 PF08585.7 EOO01991.1 - 2.9e-08 33.8 0.0 5.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Tim17 PF02466.14 EOO01992.1 - 8.1e-14 51.7 9.4 1.1e-13 51.3 6.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DNA_primase_S PF01896.14 EOO01993.1 - 2e-54 183.3 0.5 3.4e-54 182.6 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Clr5 PF14420.1 EOO01994.1 - 4.8e-20 71.1 3.1 1.1e-19 69.9 2.2 1.7 1 0 0 1 1 1 1 Clr5 domain MutS_V PF00488.16 EOO01996.1 - 1.4e-98 329.0 0.0 2.2e-98 328.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EOO01996.1 - 4.3e-40 137.7 1.4 9.3e-40 136.5 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EOO01996.1 - 8.4e-21 74.4 1.6 1.6e-20 73.5 0.0 2.4 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EOO01996.1 - 1.9e-19 69.7 0.0 9.4e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EOO01996.1 - 8.3e-05 22.6 6.5 0.024 14.7 0.3 3.8 3 1 1 4 4 4 2 MutS family domain IV AAA_22 PF13401.1 EOO01996.1 - 0.01 15.9 0.4 1.6 8.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain Peptidase_M16 PF00675.15 EOO01996.1 - 0.065 12.9 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) eIF2A PF08662.6 EOO01998.1 - 6.1e-78 260.9 0.0 2.3e-77 259.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EOO01998.1 - 0.00058 19.6 0.7 13 5.8 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EOO01998.1 - 0.0027 17.7 0.5 0.013 15.5 0.2 2.3 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 Menin PF05053.8 EOO01998.1 - 8 4.4 7.5 12 3.9 5.2 1.1 1 0 0 1 1 1 0 Menin Aminotran_1_2 PF00155.16 EOO01999.1 - 5e-36 124.4 0.0 6e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EOO01999.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF676 PF05057.9 EOO02000.1 - 0.00019 20.8 0.1 0.0013 18.0 0.0 2.1 1 1 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EOO02000.1 - 0.013 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Dot_icm_IcmQ PF09475.5 EOO02000.1 - 0.014 14.6 0.0 0.091 11.9 0.0 2.0 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Abhydrolase_6 PF12697.2 EOO02000.1 - 0.058 13.2 0.1 0.1 12.4 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Glucan_synthase PF02364.10 EOO02001.1 - 0 1451.0 0.0 0 1450.3 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EOO02001.1 - 1.3e-40 137.9 0.2 3.4e-40 136.5 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MAM33 PF02330.11 EOO02002.1 - 3.8e-35 121.5 0.2 1e-33 116.8 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein HIT PF01230.18 EOO02003.1 - 4.9e-24 84.7 0.1 6.9e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EOO02003.1 - 2.6e-14 53.4 0.0 4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EOO02003.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 EOO02003.1 - 0.2 11.3 0.8 5.5 6.7 0.2 2.2 2 0 0 2 2 2 0 Streptococcal histidine triad protein His_Phos_2 PF00328.17 EOO02004.1 - 1.1e-36 126.9 0.0 5e-20 72.1 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PI3K_1B_p101 PF10486.4 EOO02004.1 - 0.095 10.2 0.2 0.13 9.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_A_exo1 PF01612.15 EOO02005.1 - 4.3e-43 146.8 0.2 6.5e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EOO02005.1 - 4.2e-27 94.2 0.1 1.3e-26 92.7 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EOO02005.1 - 3.5e-14 52.2 0.2 1.1e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 HRDC domain Suf PF05843.9 EOO02006.1 - 9.5e-34 117.3 0.3 1.6e-31 110.1 0.0 3.2 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) Vps51 PF08700.6 EOO02007.1 - 8.5e-21 73.6 0.9 1.3e-20 73.0 0.6 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EOO02007.1 - 0.0088 14.5 0.2 0.012 14.1 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family NIF3 PF01784.13 EOO02008.1 - 1.1e-60 205.2 0.0 1.4e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) VHS PF00790.14 EOO02009.1 - 4.9e-46 155.8 0.0 3e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EOO02009.1 - 1.4e-25 89.1 0.9 4e-25 87.7 0.6 1.8 1 0 0 1 1 1 1 GAT domain Hat1_N PF10394.4 EOO02009.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus GTP_EFTU PF00009.22 EOO02011.1 - 5.2e-37 127.1 3.3 5.2e-37 127.1 2.3 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EOO02011.1 - 8.3e-27 93.2 0.6 2.6e-26 91.6 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EOO02011.1 - 2.1e-11 43.7 3.9 2.5e-07 30.7 1.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EOO02011.1 - 1.1e-06 28.5 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EOO02011.1 - 3.8e-05 24.1 0.0 9.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO02011.1 - 4.5e-05 22.7 0.0 7.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EOO02011.1 - 0.00029 20.1 0.2 0.0011 18.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EOO02011.1 - 0.00088 18.7 0.1 0.0027 17.1 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EOO02011.1 - 0.011 15.6 0.8 1.5 8.6 0.1 3.1 2 1 1 3 3 3 0 Dynamin family GTP_EFTU_D4 PF14578.1 EOO02011.1 - 0.016 14.8 0.1 0.016 14.8 0.1 3.8 4 0 0 4 4 4 0 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EOO02011.1 - 0.016 14.7 0.0 0.08 12.4 0.0 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EOO02011.1 - 0.018 14.2 0.2 0.065 12.4 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_60s PF00428.14 EOO02011.1 - 0.21 12.0 5.5 0.69 10.3 3.8 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 EOO02012.1 - 3.2e-61 206.7 0.0 4.6e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02012.1 - 1.1e-43 149.1 0.0 1.7e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02012.1 - 2.7e-09 36.4 0.0 1.4e-07 30.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EOO02012.1 - 0.0026 16.8 0.0 0.0088 15.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EOO02012.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_methylase PF00145.12 EOO02013.1 - 5.1e-32 111.3 0.0 7.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EOO02013.1 - 3.7e-06 26.6 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 2 BAH domain Asp PF00026.18 EOO02014.1 - 1.7e-110 369.1 0.6 2.1e-110 368.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO02014.1 - 9.6e-12 45.1 0.1 3.2e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO02014.1 - 2e-06 28.1 0.0 0.071 13.6 0.0 3.3 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EOO02014.1 - 1.5e-05 24.6 0.0 0.00035 20.1 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EOO02014.1 - 0.046 13.8 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain CP2 PF04516.10 EOO02015.1 - 3.2e-85 284.9 0.0 3.9e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 EOO02015.1 - 0.0058 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Major spike protein (G protein) Tektin PF03148.9 EOO02015.1 - 0.0071 14.9 0.0 0.0094 14.5 0.0 1.1 1 0 0 1 1 1 1 Tektin family CG-1 PF03859.11 EOO02015.1 - 0.037 13.5 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 CG-1 domain Neogenin_C PF06583.7 EOO02015.1 - 0.078 12.5 0.1 0.42 10.1 0.1 1.9 1 1 0 1 1 1 0 Neogenin C-terminus TMF_DNA_bd PF12329.3 EOO02015.1 - 0.087 12.6 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CorA PF01544.13 EOO02016.1 - 1.2e-10 40.8 0.1 2.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Nucleos_tra2_N PF01773.15 EOO02016.1 - 0.091 13.1 0.2 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus CobU PF02283.11 EOO02017.1 - 1.3 8.4 4.5 6.1 6.2 3.1 2.0 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Piwi PF02171.12 EOO02018.1 - 1.3e-71 241.0 0.2 1.8e-71 240.5 0.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EOO02018.1 - 3.4e-12 45.8 0.3 6.4e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EOO02018.1 - 2.1e-08 33.4 0.0 4.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) GPP34 PF05719.6 EOO02019.1 - 2.5e-65 220.3 0.2 3.2e-65 220.0 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ras PF00071.17 EOO02020.1 - 3.7e-39 133.7 0.0 2.3e-25 88.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EOO02020.1 - 5.1e-12 46.3 0.0 8.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO02020.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EOO02020.1 - 0.0019 17.4 0.0 0.0074 15.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EOO02020.1 - 0.031 13.7 0.0 0.63 9.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 EOO02020.1 - 0.054 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MFS_1 PF07690.11 EOO02021.1 - 4.7e-16 58.4 38.8 5.1e-15 55.0 26.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily SURF6 PF04935.7 EOO02022.1 - 2.8e-49 167.3 38.5 2.8e-49 167.3 26.7 3.7 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EOO02022.1 - 1.5e-07 31.3 4.5 1.5e-07 31.3 3.1 7.9 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 BNR_2 PF13088.1 EOO02023.1 - 0.00064 19.0 0.0 0.0022 17.3 0.0 1.8 1 1 0 1 1 1 1 BNR repeat-like domain IMP_cyclohyd PF07826.6 EOO02023.1 - 0.037 13.3 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein PUF PF00806.14 EOO02024.1 - 2.7e-13 48.5 0.0 0.024 14.1 0.0 6.0 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.14 EOO02024.1 - 2.4e-12 46.0 0.0 3.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MFS_1 PF07690.11 EOO02025.1 - 3.4e-36 124.6 35.8 3.4e-36 124.6 24.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C3Hc3H PF13891.1 EOO02026.1 - 0.11 12.6 0.2 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain CRAL_TRIO PF00650.15 EOO02027.1 - 1.2e-43 148.3 0.1 2.2e-43 147.4 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EOO02027.1 - 3.8e-15 55.7 2.0 1.3e-14 53.9 0.0 2.6 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EOO02027.1 - 4.3e-11 42.9 0.0 8.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Amidase PF01425.16 EOO02028.1 - 8.9e-96 321.4 0.0 1.2e-95 320.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Cu2_monoox_C PF03712.10 EOO02029.1 - 1.8e-19 69.6 0.0 3.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 EOO02029.1 - 8.1e-17 61.4 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.12 EOO02029.1 - 6.3e-16 58.4 0.1 1.8e-15 56.9 0.0 1.9 1 1 1 2 2 2 1 DOMON domain TRI12 PF06609.8 EOO02031.1 - 1.2e-22 79.9 19.8 1.7e-22 79.4 13.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EOO02031.1 - 3e-18 65.6 47.8 6.5e-16 57.9 31.4 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 EOO02032.1 - 4.3e-11 43.1 0.0 1e-10 41.8 0.0 1.5 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EOO02032.1 - 4.2e-08 32.7 0.0 4.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EOO02032.1 - 0.049 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EOO02032.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UQ_con PF00179.21 EOO02033.1 - 2.7e-30 104.6 0.0 3.4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO02033.1 - 3.7e-05 23.4 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO02033.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Nop14 PF04147.7 EOO02034.1 - 4.5e-258 858.5 25.1 5.5e-258 858.2 17.4 1.1 1 0 0 1 1 1 1 Nop14-like family Sel1 PF08238.7 EOO02035.1 - 5.6e-13 49.0 7.0 0.0012 19.4 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat RVT_2 PF07727.9 EOO02035.1 - 0.024 13.5 0.2 0.038 12.9 0.2 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M22 PF00814.20 EOO02036.1 - 3.8e-43 147.9 0.0 7.2e-39 133.8 0.0 3.8 1 1 1 2 2 2 2 Glycoprotease family YycC PF14174.1 EOO02036.1 - 0.0065 16.1 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 YycC-like protein MutL PF13941.1 EOO02036.1 - 0.027 12.7 0.0 0.043 12.1 0.0 1.2 1 0 0 1 1 1 0 MutL protein COesterase PF00135.23 EOO02037.1 - 5.7e-93 312.4 0.1 2.7e-83 280.5 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO02037.1 - 1.4e-10 41.0 0.2 3.5e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO02037.1 - 0.00018 21.3 0.2 0.00045 19.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO02037.1 - 0.015 15.2 0.8 0.027 14.3 0.6 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1168 PF06658.7 EOO02037.1 - 0.2 11.1 0.9 0.36 10.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Glyco_transf_34 PF05637.7 EOO02038.1 - 1.5e-65 221.0 0.4 2.1e-65 220.6 0.3 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RhoGAP PF00620.22 EOO02039.1 - 2.5e-37 127.8 0.2 7.2e-37 126.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EOO02039.1 - 2.5e-06 27.4 10.2 4.4e-06 26.6 5.9 2.2 2 0 0 2 2 2 1 LIM domain 2-oxoacid_dh PF00198.18 EOO02040.1 - 1e-74 250.7 0.1 1.4e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EOO02040.1 - 6e-16 57.8 0.0 1.6e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EOO02040.1 - 3.1e-11 42.6 1.6 3.7e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 e3 binding domain AAA PF00004.24 EOO02041.1 - 4.4e-50 169.2 0.0 5.5e-44 149.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EOO02041.1 - 8.8e-06 25.2 0.1 0.00015 21.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EOO02041.1 - 5.5e-05 23.9 0.0 0.00019 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EOO02041.1 - 8.8e-05 21.6 0.0 0.00027 20.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EOO02041.1 - 0.00021 21.4 0.0 0.003 17.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EOO02041.1 - 0.00031 19.6 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 EOO02041.1 - 0.00036 19.9 0.0 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EOO02041.1 - 0.00036 20.5 2.3 0.012 15.6 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.9 EOO02041.1 - 0.00098 19.0 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EOO02041.1 - 0.0011 18.6 0.1 0.0075 15.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EOO02041.1 - 0.0032 17.6 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EOO02041.1 - 0.0041 15.9 0.0 0.007 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EOO02041.1 - 0.0043 16.7 0.0 0.027 14.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EOO02041.1 - 0.0064 15.6 0.3 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EOO02041.1 - 0.0099 15.0 0.1 0.033 13.2 0.0 1.8 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 EOO02041.1 - 0.018 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EOO02041.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EOO02041.1 - 0.028 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EOO02041.1 - 0.038 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EOO02041.1 - 0.044 12.7 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EOO02041.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EOO02041.1 - 0.048 13.3 0.0 1 9.0 0.0 2.7 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.21 EOO02041.1 - 0.059 12.8 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EOO02041.1 - 0.064 12.8 1.8 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EOO02041.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Trehalase PF01204.13 EOO02042.1 - 6.7e-118 394.5 5.6 4.8e-117 391.7 3.9 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EOO02042.1 - 0.00018 20.3 0.7 0.0008 18.2 0.1 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase EF1_GNE PF00736.14 EOO02044.1 - 3.3e-31 106.8 2.5 6e-31 105.9 1.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EOO02044.1 - 1.3e-14 54.0 7.7 1.3e-14 54.0 5.3 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EOO02044.1 - 0.002 18.5 0.0 0.006 17.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EOO02044.1 - 0.11 12.4 0.4 1.5 8.7 0.3 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EOO02044.1 - 0.17 11.8 0.6 0.62 10.0 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_16 PF00722.16 EOO02045.1 - 1.3e-09 37.5 0.7 8.7e-09 34.9 0.1 2.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 EOO02045.1 - 0.052 13.1 1.7 0.1 12.2 0.3 2.2 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) Pkinase PF00069.20 EOO02046.1 - 4.3e-36 124.3 0.0 3.8e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02046.1 - 8.2e-14 51.2 0.0 0.00012 21.2 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EOO02046.1 - 0.0013 18.4 0.0 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EOO02046.1 - 0.006 15.5 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like ATP-cone PF03477.11 EOO02046.1 - 0.18 12.2 0.7 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 ATP cone domain Ribosomal_L10 PF00466.15 EOO02047.1 - 4.5e-25 87.4 0.0 1.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EOO02047.1 - 3.3e-17 62.6 6.6 4.3e-17 62.3 2.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.5 EOO02047.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 VirE N-terminal domain tRNA-synt_2d PF01409.15 EOO02049.1 - 6.4e-86 287.5 0.0 9.1e-86 287.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EOO02049.1 - 2.3e-06 26.6 0.6 0.00018 20.4 0.1 3.1 2 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EOO02049.1 - 0.00078 19.0 0.0 0.002 17.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_1e PF01406.14 EOO02050.1 - 4.6e-116 387.1 0.0 4.6e-116 387.1 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EOO02050.1 - 1.7e-06 26.9 1.0 0.0092 14.6 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Ribosomal_L29 PF00831.18 EOO02051.1 - 2.9e-17 62.1 1.5 2.9e-17 62.1 1.0 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EOO02051.1 - 0.04 14.1 0.5 0.048 13.9 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 YPEB PF14620.1 EOO02051.1 - 0.18 10.8 1.1 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 YpeB sporulation Oxidored_FMN PF00724.15 EOO02052.1 - 2.5e-77 260.1 0.0 1.5e-73 247.7 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sec63 PF02889.11 EOO02053.1 - 1.3e-195 648.7 0.0 6.5e-108 360.6 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EOO02053.1 - 1e-53 181.2 1.1 2.8e-30 105.0 0.0 4.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EOO02053.1 - 1e-16 61.3 0.0 7.5e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EOO02053.1 - 1.2e-09 37.9 0.0 1.3e-08 34.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EOO02053.1 - 2.3e-06 27.7 0.1 0.015 15.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EOO02053.1 - 0.00094 18.1 0.0 0.71 8.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.11 EOO02053.1 - 0.003 16.8 0.0 0.36 10.0 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_10 PF12846.2 EOO02053.1 - 0.075 12.4 3.6 8.6 5.7 0.0 4.6 6 1 1 7 7 7 0 AAA-like domain Peptidase_M28 PF04389.12 EOO02054.1 - 1.3e-38 132.5 0.0 1.7e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Flavi_NS4B PF01349.12 EOO02054.1 - 0.15 10.9 0.1 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B But2 PF09792.4 EOO02055.1 - 8e-06 25.6 0.2 1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain IU_nuc_hydro PF01156.14 EOO02056.1 - 2.3e-54 184.7 0.0 1.4e-43 149.3 0.0 2.0 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DnaJ PF00226.26 EOO02057.1 - 2e-25 88.3 2.7 3.5e-25 87.4 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EOO02057.1 - 3.1e-21 75.0 0.0 6e-18 64.5 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EOO02057.1 - 1.2e-14 54.1 17.7 2.2e-14 53.2 12.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EOO02057.1 - 0.0013 18.3 9.0 0.055 13.1 1.6 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EOO02057.1 - 0.19 11.5 6.4 2.4 8.0 1.2 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 EOO02057.1 - 0.27 11.0 4.3 2.1 8.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 EOO02057.1 - 1.7 8.7 7.4 22 5.1 0.1 3.7 4 0 0 4 4 4 0 zinc-finger Opy2 PF09463.5 EOO02057.1 - 2 8.5 6.3 5.7 7.1 0.7 3.0 3 0 0 3 3 3 0 Opy2 protein Lar_restr_allev PF14354.1 EOO02057.1 - 5.6 7.3 8.8 87 3.5 6.2 2.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar MutS_V PF00488.16 EOO02058.1 - 2.1e-79 266.2 0.0 3.5e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EOO02058.1 - 5.3e-36 124.3 5.0 8.3e-36 123.6 3.4 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EOO02058.1 - 5.8e-19 68.1 0.0 1.7e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EOO02058.1 - 1.3e-09 38.1 0.0 4.5e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EOO02058.1 - 0.0021 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EOO02058.1 - 0.032 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EOO02058.1 - 0.078 12.9 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EOO02058.1 - 0.094 12.8 0.2 2.1 8.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EOO02058.1 - 0.12 12.7 0.1 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.1 EOO02059.1 - 7.1e-28 97.5 0.0 8.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EOO02059.1 - 8e-07 29.1 0.0 9.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO02059.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EOO02059.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sld5 PF05916.6 EOO02060.1 - 4.1e-13 49.5 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein Cgr1 PF03879.9 EOO02061.1 - 1.3e-35 121.8 32.5 1.4e-35 121.7 22.5 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EOO02061.1 - 0.0098 16.2 10.5 0.012 15.9 7.3 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Prismane PF03063.15 EOO02061.1 - 0.59 8.4 4.9 0.64 8.3 3.4 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Silic_transp PF03842.8 EOO02061.1 - 5.4 4.9 6.2 6 4.8 4.3 1.0 1 0 0 1 1 1 0 Silicon transporter COPIIcoated_ERV PF07970.7 EOO02062.1 - 5.2e-72 242.0 0.0 5e-48 163.6 0.0 2.4 3 0 0 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EOO02062.1 - 3.5e-10 39.7 0.3 8.4e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PhoD PF09423.5 EOO02063.1 - 1.3e-09 37.2 0.0 1.4e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase UreF PF01730.11 EOO02064.1 - 0.11 12.6 1.7 0.15 12.1 0.5 1.7 1 1 1 2 2 2 0 UreF zf-HC5HC2H_2 PF13832.1 EOO02065.1 - 1.5e-19 70.0 1.5 1.5e-19 70.0 1.0 4.2 5 0 0 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EOO02065.1 - 8.8e-18 64.2 22.3 1.1e-17 63.9 1.7 4.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EOO02065.1 - 3.9e-17 62.1 0.1 7.8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EOO02065.1 - 7.7e-12 44.7 56.3 1.1e-06 28.2 5.8 6.0 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EOO02065.1 - 2.1e-08 33.3 3.7 2.1e-08 33.3 2.5 5.5 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 EOO02065.1 - 2.6e-05 23.8 33.8 0.076 12.7 1.2 4.3 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 C1_1 PF00130.17 EOO02065.1 - 0.0033 17.1 2.5 0.0033 17.1 1.7 5.7 5 1 1 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) ELM2 PF01448.19 EOO02065.1 - 0.037 14.6 0.0 0.52 10.9 0.0 2.8 2 0 0 2 2 2 0 ELM2 domain TrkA_C PF02080.16 EOO02065.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain GATA PF00320.22 EOO02065.1 - 2.3 7.6 13.1 0.029 13.7 0.4 3.8 4 0 0 4 4 4 0 GATA zinc finger EMP24_GP25L PF01105.19 EOO02066.1 - 3.3e-45 154.0 0.0 3.7e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 EOO02066.1 - 0.0034 16.6 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase SpoU_methylase PF00588.14 EOO02066.1 - 0.0089 15.9 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 1 SpoU rRNA Methylase family dCMP_cyt_deam_1 PF00383.17 EOO02067.1 - 3.8e-09 36.1 0.1 6.1e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EOO02067.1 - 0.057 13.2 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase DUF2417 PF10329.4 EOO02068.1 - 9.4e-44 149.5 2.4 1.3e-43 149.0 1.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EOO02068.1 - 8.9e-07 29.0 0.1 1.4e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EOO02069.1 - 1.3e-73 248.1 0.0 1.6e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.3 EOO02069.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) DEAD PF00270.24 EOO02070.1 - 5.3e-43 146.4 0.0 3.8e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO02070.1 - 1e-23 83.0 0.0 3.4e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO02070.1 - 0.018 14.8 0.0 0.15 11.8 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EOO02070.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Arf PF00025.16 EOO02071.1 - 1.4e-79 265.3 0.2 1.7e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EOO02071.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EOO02071.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EOO02071.1 - 2.2e-12 46.3 1.7 2.3e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EOO02071.1 - 3.7e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EOO02071.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO02071.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EOO02071.1 - 0.0087 15.1 0.6 0.018 14.0 0.4 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EOO02071.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EOO02071.1 - 0.04 13.7 0.2 0.097 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain LSM PF01423.17 EOO02072.1 - 1e-16 60.2 0.0 1.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain ORC3_N PF07034.6 EOO02073.1 - 6.3e-38 130.5 1.3 6.3e-38 130.5 0.9 1.9 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus O-FucT PF10250.4 EOO02074.1 - 2.1e-07 30.4 0.1 6.5e-07 28.7 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NPL4 PF05021.10 EOO02075.1 - 5.9e-130 432.8 0.0 7.2e-130 432.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EOO02075.1 - 6.4e-69 230.2 0.1 1.1e-68 229.5 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EOO02075.1 - 0.0024 18.1 0.0 0.0075 16.5 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 EOO02075.1 - 0.015 15.0 0.4 0.029 14.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) HMG_box_2 PF09011.5 EOO02076.1 - 6.4e-11 42.4 3.1 2.9e-07 30.7 0.5 3.0 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EOO02076.1 - 4.8e-10 39.5 0.2 4.8e-10 39.5 0.2 3.5 3 0 0 3 3 3 2 HMG (high mobility group) box FAD_binding_2 PF00890.19 EOO02077.1 - 1.8e-122 409.1 3.9 2.2e-122 408.9 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EOO02077.1 - 8.5e-47 158.2 0.6 1.2e-46 157.6 0.4 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EOO02077.1 - 1.2e-05 25.2 0.1 0.067 13.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO02077.1 - 1.8e-05 23.9 0.2 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EOO02077.1 - 0.00031 19.7 0.8 0.14 11.0 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EOO02077.1 - 0.0013 17.7 0.1 0.005 15.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EOO02077.1 - 0.01 14.8 0.1 0.01 14.8 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain CPSase_L_D2 PF02786.12 EOO02078.1 - 3e-109 363.2 0.0 7.8e-85 283.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EOO02078.1 - 1.2e-40 138.0 0.0 3.2e-40 136.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EOO02078.1 - 2.3e-38 131.8 0.0 2.5e-20 72.9 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EOO02078.1 - 3e-35 120.6 0.0 1.9e-16 60.1 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EOO02078.1 - 4.8e-24 84.7 0.0 2.2e-08 33.2 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EOO02078.1 - 7.3e-22 77.5 0.1 3.1e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EOO02078.1 - 4.5e-17 62.1 0.6 1.2e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EOO02078.1 - 1e-09 38.1 0.0 5.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EOO02078.1 - 5.2e-07 29.6 0.1 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EOO02078.1 - 1.4e-06 27.9 0.4 0.032 13.7 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EOO02078.1 - 6e-05 22.3 0.1 0.044 12.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EOO02078.1 - 0.064 13.1 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain COPI_C PF06957.6 EOO02079.1 - 0.56 8.6 7.7 1 7.7 5.3 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.7 EOO02079.1 - 1.6 7.8 4.8 3.5 6.8 3.3 1.5 1 0 0 1 1 1 0 NOA36 protein Sec66 PF09802.4 EOO02080.1 - 3.1e-81 271.2 0.1 3.6e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Kinesin PF00225.18 EOO02081.1 - 2.7e-96 322.1 1.5 3.1e-96 321.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain ECIST_Cterm PF14784.1 EOO02081.1 - 0.052 13.5 0.2 16 5.4 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Vfa1 PF08432.5 EOO02081.1 - 2 8.3 12.4 0.17 11.9 2.1 3.0 2 1 1 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Tom37_C PF11801.3 EOO02081.1 - 7.1 6.4 7.3 18 5.1 2.0 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain V_ATPase_I PF01496.14 EOO02081.1 - 7.3 4.3 8.9 1.6 6.4 0.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Proteasome PF00227.21 EOO02082.1 - 1.1e-46 158.5 0.1 1.4e-46 158.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EOO02082.1 - 7.7e-13 47.4 0.3 1.9e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF836 PF05768.9 EOO02084.1 - 4e-10 39.8 0.0 5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EOO02084.1 - 0.045 13.7 0.1 0.089 12.7 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin CHORD PF04968.7 EOO02086.1 - 4.1e-52 174.2 19.4 4.8e-26 90.7 4.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EOO02086.1 - 7.3e-15 55.2 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 CS domain TALPID3 PF15324.1 EOO02086.1 - 1.3 6.2 7.9 1.7 5.8 5.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF4187 PF13821.1 EOO02087.1 - 9.7e-17 60.3 3.5 3.6e-16 58.4 2.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EOO02087.1 - 9.6e-09 34.8 1.6 1.9e-08 33.9 1.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EOO02087.1 - 0.0094 15.7 1.9 0.052 13.4 1.1 2.6 1 1 0 1 1 1 1 DExH-box splicing factor binding site MAP7 PF05672.6 EOO02087.1 - 9 5.6 35.3 0.033 13.5 10.1 3.2 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family UQ_con PF00179.21 EOO02088.1 - 6.4e-11 41.8 0.6 1e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme 3Beta_HSD PF01073.14 EOO02089.1 - 1.3e-66 224.1 0.0 1.5e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EOO02089.1 - 5e-30 104.6 0.2 6.8e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EOO02089.1 - 1.1e-15 57.2 1.0 2e-13 49.8 0.7 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EOO02089.1 - 2e-14 53.1 0.1 2.8e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EOO02089.1 - 5.9e-11 42.7 0.1 1.3e-10 41.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EOO02089.1 - 2.9e-07 29.6 0.1 6.9e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EOO02089.1 - 7.8e-06 25.9 0.5 2.4e-05 24.3 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02089.1 - 0.00042 20.0 1.8 0.003 17.2 1.3 2.1 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 EOO02089.1 - 0.0068 16.3 0.1 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 EOO02089.1 - 0.012 15.9 0.0 0.034 14.5 0.0 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF3798 PF12683.2 EOO02089.1 - 0.02 14.0 0.4 0.032 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Stk19 PF10494.4 EOO02091.1 - 3.7e-66 223.0 0.0 5.5e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.15 EOO02091.1 - 2.5e-30 105.4 2.1 2.5e-30 105.4 1.5 1.7 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EOO02091.1 - 2.6e-15 56.0 0.0 5.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EOO02091.1 - 6.4e-10 38.4 0.0 1.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain SKI PF01202.17 EOO02092.1 - 0.00082 19.2 0.0 0.00096 19.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EOO02092.1 - 0.00082 19.6 0.1 0.0031 17.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EOO02092.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ribosomal_L6e PF01159.14 EOO02093.1 - 3e-38 130.3 0.4 4.6e-38 129.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e NPV_P10 PF05531.7 EOO02094.1 - 2.4e-05 24.5 6.6 0.026 14.7 0.3 3.3 4 0 0 4 4 2 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EOO02094.1 - 0.00017 20.1 3.4 0.00017 20.1 2.3 2.7 2 1 1 3 3 3 1 AAA domain DUF3584 PF12128.3 EOO02094.1 - 0.00029 18.3 22.0 0.00039 17.9 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Phage_GP20 PF06810.6 EOO02094.1 - 0.00091 18.6 13.0 0.16 11.4 0.1 3.8 4 0 0 4 4 4 2 Phage minor structural protein GP20 Filament PF00038.16 EOO02094.1 - 0.004 16.6 32.8 0.023 14.1 1.4 3.3 1 1 1 3 3 3 2 Intermediate filament protein Mod_r PF07200.8 EOO02094.1 - 0.21 11.5 16.7 0.05 13.5 2.8 3.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 EOO02094.1 - 0.21 10.7 5.1 0.66 9.0 0.3 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Zn_ribbon_2 PF12674.2 EOO02094.1 - 0.24 11.7 1.2 11 6.4 0.0 3.1 3 0 0 3 3 2 0 Putative zinc ribbon domain Glyco_hydro_4C PF11975.3 EOO02094.1 - 0.25 11.1 3.7 5.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain PilJ PF13675.1 EOO02094.1 - 0.39 11.0 17.6 0.1 12.8 1.8 3.8 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 EOO02094.1 - 0.48 10.5 16.3 0.11 12.6 2.3 4.1 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-CCHC_2 PF13696.1 EOO02094.1 - 0.51 9.8 1.3 5.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Pkip-1 PF06878.6 EOO02094.1 - 0.75 9.6 7.7 0.5 10.2 2.0 2.4 1 1 1 2 2 2 0 Pkip-1 protein Laminin_II PF06009.7 EOO02094.1 - 0.77 9.5 12.0 0.87 9.3 0.9 3.6 3 1 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EOO02094.1 - 0.78 9.5 4.1 1.3 8.8 0.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 EOO02094.1 - 0.84 9.3 27.2 13 5.5 11.6 3.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EOO02094.1 - 0.92 9.4 7.3 2.1 8.3 0.2 3.7 4 0 0 4 4 4 0 FlxA-like protein DASH_Dam1 PF08653.5 EOO02094.1 - 1.3 8.8 2.9 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-CCHC_4 PF14392.1 EOO02094.1 - 1.3 8.7 3.9 12 5.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Spc7 PF08317.6 EOO02094.1 - 1.4 7.5 26.2 0.049 12.2 4.8 3.2 1 1 0 3 3 3 0 Spc7 kinetochore protein MscS_porin PF12795.2 EOO02094.1 - 1.6 7.9 20.3 0.39 9.9 1.5 3.2 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain Fez1 PF06818.10 EOO02094.1 - 1.9 8.4 34.6 0.053 13.5 11.0 3.3 2 1 1 3 3 3 0 Fez1 DivIVA PF05103.8 EOO02094.1 - 2.5 8.1 23.8 0.23 11.4 2.7 3.8 2 1 2 4 4 4 0 DivIVA protein TMF_DNA_bd PF12329.3 EOO02094.1 - 3 7.6 39.1 0.55 10.0 2.3 5.8 4 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding Nsp1_C PF05064.8 EOO02094.1 - 3.4 7.3 9.8 2.5 7.7 1.7 3.0 3 0 0 3 3 3 0 Nsp1-like C-terminal region TBPIP PF07106.8 EOO02094.1 - 3.6 7.0 17.7 0.45 10.0 1.8 3.6 4 0 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EOO02094.1 - 4.7 7.3 13.1 1.5 8.8 0.6 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ISG65-75 PF11727.3 EOO02094.1 - 7.2 5.5 15.2 1.8 7.5 3.4 2.5 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF3450 PF11932.3 EOO02094.1 - 7.3 5.7 16.2 0.8 8.9 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Occludin_ELL PF07303.8 EOO02094.1 - 7.5 7.3 12.5 1.8 9.3 1.0 3.4 3 0 0 3 3 3 0 Occludin homology domain DUF948 PF06103.6 EOO02094.1 - 7.9 6.4 7.3 0.63 9.9 0.6 2.4 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EOO02094.1 - 9.9 6.2 23.0 2 8.4 4.0 4.3 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Aldedh PF00171.17 EOO02095.1 - 2.3e-108 362.5 0.0 2.7e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF758 PF05527.6 EOO02096.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF758) DUF2976 PF11190.3 EOO02096.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Rhomboid PF01694.17 EOO02097.1 - 6.3e-19 68.4 4.0 6.3e-19 68.4 2.8 1.5 2 0 0 2 2 2 1 Rhomboid family Glyco_hydro_38 PF01074.17 EOO02098.1 - 1.4e-90 303.2 0.4 2.5e-90 302.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EOO02098.1 - 2.3e-76 257.4 0.1 5.6e-76 256.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EOO02098.1 - 2.9e-27 94.6 0.0 5.6e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DUF3074 PF11274.3 EOO02099.1 - 1.2e-43 148.8 0.0 1.8e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF1237 PF06824.6 EOO02100.1 - 1.2e-175 584.2 0.0 1.5e-175 583.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) He_PIG PF05345.7 EOO02101.1 - 0.01 15.8 1.5 0.17 11.9 0.2 2.7 2 0 0 2 2 2 0 Putative Ig domain Abhydro_lipase PF04083.11 EOO02102.1 - 5.8e-21 73.6 0.0 1.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EOO02102.1 - 4e-07 30.1 0.1 9.4e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02102.1 - 0.00065 19.4 0.0 0.001 18.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO02102.1 - 0.044 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PYST-C1 PF09690.5 EOO02102.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Nop14 PF04147.7 EOO02103.1 - 0.41 8.5 18.6 0.5 8.2 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EOO02103.1 - 0.44 8.9 15.3 0.87 7.9 10.6 1.4 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EOO02103.1 - 1.3 7.3 13.9 2 6.6 9.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_3_Rpc31 PF11705.3 EOO02103.1 - 1.7 8.5 22.7 3.6 7.4 15.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EOO02103.1 - 2.4 7.9 26.3 4.5 7.0 18.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EOO02103.1 - 4.4 5.2 12.1 7.1 4.5 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EOO02103.1 - 8.5 5.9 15.1 17 4.9 10.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA PF00004.24 EOO02104.1 - 6.9e-16 58.6 0.0 2e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EOO02104.1 - 7e-13 48.5 0.0 2.8e-07 30.3 0.0 2.5 3 0 0 3 3 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EOO02104.1 - 1e-12 47.5 0.0 4.3e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EOO02104.1 - 8.3e-11 41.7 0.0 5.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EOO02104.1 - 5.5e-07 29.7 0.1 0.00011 22.3 0.0 3.3 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EOO02104.1 - 1.8e-06 27.1 0.0 5.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EOO02104.1 - 2.1e-05 24.2 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02104.1 - 2.3e-05 24.0 0.0 6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EOO02104.1 - 2.6e-05 24.3 0.1 0.00096 19.1 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EOO02104.1 - 0.00019 21.3 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EOO02104.1 - 0.00033 19.8 0.0 0.022 13.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EOO02104.1 - 0.00096 18.8 0.1 0.032 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EOO02104.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EOO02104.1 - 0.0019 17.6 0.0 0.01 15.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EOO02104.1 - 0.0021 18.8 0.0 0.0057 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EOO02104.1 - 0.0028 17.2 0.2 0.0071 15.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EOO02104.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EOO02104.1 - 0.0054 15.6 0.0 0.0084 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EOO02104.1 - 0.0055 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EOO02104.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_3 PF07726.6 EOO02104.1 - 0.011 15.3 0.0 0.057 13.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EOO02104.1 - 0.015 15.5 0.1 0.064 13.5 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EOO02104.1 - 0.022 14.3 0.1 0.27 10.7 0.0 2.7 2 2 1 3 3 3 0 AAA domain TIP49 PF06068.8 EOO02104.1 - 0.031 13.0 0.0 0.46 9.1 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 EOO02104.1 - 0.044 13.4 0.0 0.6 9.7 0.0 2.2 2 1 0 3 3 2 0 Archaeal ATPase AAA_33 PF13671.1 EOO02104.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.8 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EOO02104.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 EOO02104.1 - 0.077 12.8 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EOO02104.1 - 0.091 12.1 0.1 1 8.7 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain SNF2_N PF00176.18 EOO02104.1 - 0.096 11.4 0.0 2.1 7.0 0.0 2.4 3 0 0 3 3 3 0 SNF2 family N-terminal domain Proteasome PF00227.21 EOO02105.1 - 1.1e-48 165.0 0.2 1.3e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 EOO02105.1 - 0.012 15.4 0.6 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF554 PF04474.7 EOO02105.1 - 0.019 14.1 0.1 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Paramyxo_P PF01806.12 EOO02106.1 - 0.17 11.1 0.8 2.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region Clathrin_lg_ch PF01086.12 EOO02107.1 - 0.076 12.9 6.4 0.098 12.5 4.5 1.0 1 0 0 1 1 1 0 Clathrin light chain Herpes_capsid PF06112.6 EOO02107.1 - 0.39 10.7 7.3 0.45 10.5 5.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein eIF-3c_N PF05470.7 EOO02107.1 - 0.79 7.7 4.7 0.84 7.6 3.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Apt1 PF10351.4 EOO02107.1 - 1.9 7.2 8.5 2.3 6.9 5.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 EOO02107.1 - 2.4 6.1 10.1 2.8 5.9 7.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3818 PF12825.2 EOO02108.1 - 5.1e-129 429.8 10.6 6.3e-127 422.9 7.4 2.2 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EOO02108.1 - 1.2e-43 148.0 0.8 2.8e-43 146.8 0.6 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EOO02108.1 - 5e-17 61.7 0.2 6.4e-16 58.1 0.0 2.9 3 1 0 3 3 3 1 PX domain Myc_N PF01056.13 EOO02108.1 - 0.031 13.4 1.4 0.067 12.3 1.0 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Synaphin PF05835.7 EOO02109.1 - 0.3 11.2 4.4 0.55 10.3 0.2 2.0 1 1 1 2 2 2 0 Synaphin protein DUF4407 PF14362.1 EOO02109.1 - 0.71 8.7 3.6 0.83 8.5 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 EOO02110.1 - 0.0076 16.0 0.0 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat HpcH_HpaI PF03328.9 EOO02111.1 - 1.5e-12 46.8 0.3 2e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MtmB PF05369.7 EOO02111.1 - 0.041 12.0 0.0 0.047 11.8 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB PK PF00224.16 EOO02111.1 - 0.043 12.4 0.2 0.07 11.7 0.2 1.4 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Beta_elim_lyase PF01212.16 EOO02112.1 - 2.6e-65 220.4 0.0 3.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EOO02112.1 - 1.1e-05 23.9 0.0 1.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Anp1 PF03452.9 EOO02113.1 - 2.5e-109 364.6 0.0 2.9e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EOO02113.1 - 0.0067 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 AICARFT_IMPCHas PF01808.13 EOO02114.1 - 6.4e-112 373.7 0.0 8.2e-112 373.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EOO02114.1 - 8.1e-24 83.3 0.0 1.5e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF4504 PF14953.1 EOO02115.1 - 0.034 13.4 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Proteasom_Rpn13 PF04683.8 EOO02116.1 - 3.4e-27 94.3 0.0 1.1e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.17 EOO02116.1 - 7.5e-13 47.9 1.2 5.2e-05 22.8 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02116.1 - 1.1e-10 41.3 0.1 0.00031 20.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02116.1 - 2.7e-05 23.8 0.0 8.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L27_2 PF09045.5 EOO02116.1 - 0.039 13.5 0.4 0.098 12.2 0.3 1.6 1 0 0 1 1 1 0 L27_2 Fib_alpha PF08702.5 EOO02117.1 - 0.00038 20.5 1.6 0.00069 19.7 1.1 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EOO02117.1 - 0.0013 17.4 0.7 0.002 16.8 0.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2077 PF09850.4 EOO02117.1 - 0.0054 16.1 0.7 0.0096 15.3 0.3 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2077) DUF2205 PF10224.4 EOO02117.1 - 0.03 13.8 0.7 0.23 11.0 0.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Laminin_II PF06009.7 EOO02117.1 - 0.079 12.7 0.5 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Laminin Domain II MCPsignal PF00015.16 EOO02117.1 - 0.084 12.4 0.6 0.19 11.2 0.3 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Occludin_ELL PF07303.8 EOO02117.1 - 0.086 13.5 1.5 0.18 12.5 0.5 1.9 1 1 0 1 1 1 0 Occludin homology domain EMP24_GP25L PF01105.19 EOO02117.1 - 0.089 12.5 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 EOO02117.1 - 0.11 12.0 3.7 0.15 11.5 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Put_DNA-bind_N PF06971.8 EOO02117.1 - 0.11 12.2 0.5 0.75 9.6 0.0 2.6 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus Sec34 PF04136.10 EOO02117.1 - 0.13 11.9 0.8 1 9.0 0.1 2.2 1 1 1 2 2 2 0 Sec34-like family DUF4140 PF13600.1 EOO02117.1 - 0.13 12.6 1.7 0.86 10.0 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.7 EOO02117.1 - 0.17 11.8 1.2 6 6.8 0.2 2.6 2 0 0 2 2 2 0 Phage shock protein B SlyX PF04102.7 EOO02117.1 - 0.17 12.2 3.5 0.18 12.2 1.2 1.9 2 0 0 2 2 2 0 SlyX DUF607 PF04678.8 EOO02117.1 - 0.26 11.2 1.7 0.63 9.9 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF904 PF06005.7 EOO02117.1 - 0.3 11.4 5.3 13 6.2 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Snapin_Pallidin PF14712.1 EOO02117.1 - 0.3 11.4 2.8 0.95 9.8 0.7 2.4 1 1 0 2 2 2 0 Snapin/Pallidin Prominin PF05478.6 EOO02117.1 - 2.6 5.4 6.8 0.56 7.6 1.3 1.8 1 1 1 2 2 2 0 Prominin Atg14 PF10186.4 EOO02117.1 - 3.4 6.5 6.6 3.9 6.3 3.0 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_C15 PF01470.12 EOO02118.1 - 3e-13 50.0 0.0 1.4e-06 28.2 0.0 2.3 2 1 0 2 2 2 2 Pyroglutamyl peptidase YLP PF02757.12 EOO02118.1 - 1.5 8.7 4.6 1.9 8.4 0.4 2.7 2 0 0 2 2 2 0 YLP motif CAP_GLY PF01302.20 EOO02119.1 - 2.1e-09 36.9 3.3 3.4e-09 36.2 2.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain RTC PF01137.16 EOO02120.1 - 2.7e-29 101.5 0.0 3.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EOO02120.1 - 1.5e-27 95.6 0.1 2.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AAA_2 PF07724.9 EOO02121.1 - 1.4e-43 148.7 0.0 1.5e-42 145.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EOO02121.1 - 5.2e-26 90.3 0.2 1.5e-25 88.8 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EOO02121.1 - 1.4e-19 70.6 0.0 2e-10 40.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EOO02121.1 - 1.2e-12 47.7 0.0 8e-09 35.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EOO02121.1 - 3.3e-11 43.5 9.8 0.00018 21.5 0.0 4.8 3 2 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EOO02121.1 - 4.7e-09 36.4 0.1 0.0022 18.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EOO02121.1 - 3e-07 30.0 0.3 0.00038 19.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EOO02121.1 - 4.3e-06 26.6 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EOO02121.1 - 7.9e-06 25.7 4.7 0.1 12.2 0.1 4.5 2 2 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 EOO02121.1 - 3e-05 23.7 0.2 0.24 11.0 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EOO02121.1 - 0.0001 23.1 5.6 0.022 15.5 0.0 3.9 4 1 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 EOO02121.1 - 0.00019 20.8 0.0 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 EOO02121.1 - 0.00027 21.2 0.9 0.23 11.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.1 EOO02121.1 - 0.0007 19.9 8.6 0.13 12.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EOO02121.1 - 0.00083 19.0 0.0 0.099 12.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EOO02121.1 - 0.0016 18.1 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EOO02121.1 - 0.002 18.0 0.0 3 7.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EOO02121.1 - 0.0028 17.0 0.7 1.7 8.0 0.0 3.1 2 2 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 EOO02121.1 - 0.005 17.0 0.0 0.83 9.8 0.0 3.1 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EOO02121.1 - 0.0051 16.7 0.6 9.1 6.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 EOO02121.1 - 0.0065 15.6 0.0 2.8 7.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EOO02121.1 - 0.0066 15.6 0.1 2.5 7.2 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 EOO02121.1 - 0.009 15.4 0.0 0.42 10.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EOO02121.1 - 0.01 15.3 0.0 0.6 9.4 0.0 3.3 2 2 0 2 2 2 1 AAA-like domain AAA_30 PF13604.1 EOO02121.1 - 0.012 15.1 0.4 0.87 9.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain PhoH PF02562.11 EOO02121.1 - 0.019 14.1 0.1 0.46 9.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EOO02121.1 - 0.021 14.6 2.9 4.8 6.9 0.0 3.6 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 EOO02121.1 - 0.03 13.2 0.4 1 8.2 0.1 3.1 3 2 0 3 3 2 0 Protein of unknown function (DUF815) PIF1 PF05970.9 EOO02121.1 - 0.035 13.0 0.0 3.7 6.3 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase PduV-EutP PF10662.4 EOO02121.1 - 0.035 13.5 0.0 0.99 8.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADIP PF11559.3 EOO02121.1 - 0.076 12.9 10.2 0.16 11.8 7.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Miro PF08477.8 EOO02121.1 - 0.08 13.4 0.1 6.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EOO02121.1 - 0.098 12.2 0.1 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain OEP PF02321.13 EOO02121.1 - 0.1 12.1 13.0 0.044 13.3 6.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein APG6 PF04111.7 EOO02121.1 - 0.19 10.7 6.5 0.33 9.9 4.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_15 PF13175.1 EOO02121.1 - 0.25 10.3 2.5 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain V_ATPase_I PF01496.14 EOO02121.1 - 0.32 8.7 3.9 0.45 8.3 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EOO02121.1 - 0.38 9.6 7.9 0.69 8.7 5.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EOO02121.1 - 0.43 10.4 5.9 1.2 9.0 4.1 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EOO02121.1 - 0.96 9.0 11.3 2.4 7.6 7.8 1.6 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EOO02121.1 - 0.99 9.6 17.1 1.3e+02 2.7 11.3 3.2 2 1 0 2 2 2 0 AAA domain Mnd1 PF03962.10 EOO02121.1 - 1.1 8.8 11.0 2.2 7.8 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 EOO02121.1 - 2.1 8.4 16.4 0.92 9.5 8.3 2.8 3 0 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 EOO02121.1 - 3.2 7.2 10.5 8.6 5.8 7.3 1.7 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EOO02121.1 - 4.3 7.3 9.9 1.4 8.9 3.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF3405 PF11885.3 EOO02122.1 - 7.6e-212 703.9 6.6 9.9e-212 703.5 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Peptidase_M49 PF03571.10 EOO02123.1 - 7.4e-225 747.1 0.0 8.8e-225 746.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 NodZ PF05830.6 EOO02125.1 - 0.1 11.1 1.6 5.8 5.4 0.1 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) PWWP PF00855.12 EOO02126.1 - 9e-15 54.6 0.0 4.8e-14 52.3 0.0 2.4 1 1 0 1 1 1 1 PWWP domain Per1 PF04080.8 EOO02127.1 - 3.4e-105 351.2 6.2 4.2e-105 350.9 4.3 1.1 1 0 0 1 1 1 1 Per1-like SH3BGR PF04908.10 EOO02128.1 - 0.00014 21.7 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein ATP-synt_10 PF05176.9 EOO02130.1 - 1.5e-86 289.8 0.0 1.7e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Sugar_tr PF00083.19 EOO02133.1 - 1.5e-23 83.1 1.1 3.1e-15 55.7 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter A_deaminase PF00962.17 EOO02134.1 - 1.6e-29 102.9 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase FAD_binding_4 PF01565.18 EOO02135.1 - 5.1e-22 77.8 2.1 9.1e-22 77.0 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain PIF1 PF05970.9 EOO02136.1 - 1.2e-57 195.5 3.6 1.1e-54 185.8 0.4 2.7 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EOO02136.1 - 8e-17 61.4 0.0 1.9e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EOO02136.1 - 1.9e-07 31.2 0.0 7.3e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO02136.1 - 6.3e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EOO02136.1 - 5.5e-05 23.2 0.0 0.00049 20.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EOO02136.1 - 6e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 EOO02136.1 - 6.4e-05 20.9 0.8 0.0014 16.4 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 EOO02136.1 - 0.00077 19.4 0.4 0.0028 17.6 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain T2SE PF00437.15 EOO02136.1 - 0.006 15.5 0.1 0.016 14.1 0.1 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EOO02136.1 - 0.0068 16.5 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EOO02136.1 - 0.0096 15.8 0.0 0.035 14.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EOO02136.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EOO02136.1 - 0.015 14.7 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EOO02136.1 - 0.018 14.4 0.3 0.34 10.3 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain PhoH PF02562.11 EOO02136.1 - 0.02 14.1 0.1 0.086 12.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF258 PF03193.11 EOO02136.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EOO02136.1 - 0.029 14.6 0.0 0.14 12.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EOO02136.1 - 0.035 13.8 0.2 0.3 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.11 EOO02136.1 - 0.041 12.6 0.1 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.4 EOO02136.1 - 0.042 12.8 0.0 0.092 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EOO02136.1 - 0.048 13.7 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TEX33 PF15400.1 EOO02136.1 - 0.064 13.6 0.2 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family Peptidase_M74 PF03411.8 EOO02136.1 - 0.08 12.1 0.0 0.08 12.1 0.0 2.0 2 0 0 2 2 1 0 Penicillin-insensitive murein endopeptidase Sigma54_activat PF00158.21 EOO02136.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EOO02136.1 - 0.1 11.4 0.1 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EOO02136.1 - 0.11 12.1 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 1 0 NTPase Arch_ATPase PF01637.13 EOO02136.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase YjeF_N PF03853.10 EOO02137.1 - 2e-37 128.4 0.0 2.9e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EOO02137.1 - 6.6e-12 45.8 0.3 6.6e-12 45.8 0.2 2.1 2 0 0 2 2 2 1 FDF domain ADH_N PF08240.7 EOO02138.1 - 3e-24 84.8 4.0 4.9e-24 84.1 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO02138.1 - 5.6e-15 55.0 0.1 1.5e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EOO02138.1 - 4.7e-05 22.6 0.0 7.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adenine_deam_C PF13382.1 EOO02139.1 - 5e-49 165.7 0.0 1.2e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 EOO02139.1 - 8.2e-19 68.4 0.1 1.4e-09 38.0 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EOO02139.1 - 2.3e-14 54.1 6.3 9.8e-07 29.0 2.0 2.4 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EOO02139.1 - 3.2e-12 46.0 1.5 6.5e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EOO02139.1 - 0.0021 17.3 2.3 0.66 9.1 0.2 2.4 1 1 0 2 2 2 2 Amidohydrolase family Trypsin PF00089.21 EOO02140.1 - 6.2e-06 25.9 0.2 1.5e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EOO02140.1 - 0.0046 16.9 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Sugar_tr PF00083.19 EOO02141.1 - 4.6e-39 134.2 15.0 5e-39 134.1 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02141.1 - 1.6e-12 46.8 21.7 1.1e-11 44.1 15.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Scs3p PF10261.4 EOO02142.1 - 1.1e-62 211.2 4.8 1.4e-62 210.8 3.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.4 EOO02142.1 - 1.8e-14 53.2 0.0 3.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Cation_efflux PF01545.16 EOO02142.1 - 0.11 11.5 0.4 0.17 10.8 0.3 1.2 1 0 0 1 1 1 0 Cation efflux family COesterase PF00135.23 EOO02143.1 - 3.6e-56 190.9 0.9 1.3e-29 103.3 0.1 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO02143.1 - 2.6e-09 36.9 0.2 6.1e-07 29.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO02143.1 - 0.046 13.4 0.1 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Oxidored_FMN PF00724.15 EOO02145.1 - 8.3e-38 130.2 0.0 1.6e-31 109.5 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EOO02145.1 - 0.0011 17.8 0.1 0.032 13.0 0.0 2.3 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) DUF1382 PF07131.6 EOO02145.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) AP_endonuc_2 PF01261.19 EOO02145.1 - 0.048 12.9 0.2 0.92 8.7 0.1 2.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel MTHFR PF02219.12 EOO02145.1 - 0.059 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase WD40 PF00400.27 EOO02146.1 - 1.5e-44 148.3 12.5 2.9e-09 36.4 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EOO02146.1 - 1.9e-10 40.3 0.6 4.1e-10 39.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EOO02146.1 - 5.8e-07 29.0 0.0 1.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EOO02146.1 - 4e-06 25.2 4.5 0.033 12.3 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EOO02146.1 - 0.0013 18.2 0.1 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EOO02146.1 - 0.0025 16.1 0.0 0.0063 14.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Fungal_trans PF04082.13 EOO02147.1 - 4e-06 25.8 1.9 1.8e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain LRAT PF04970.8 EOO02147.1 - 0.12 12.2 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Pectate_lyase_3 PF12708.2 EOO02148.1 - 2.1e-92 309.3 20.9 8e-72 241.9 7.7 2.6 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EOO02148.1 - 1.5e-06 27.5 4.1 0.0051 16.2 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EOO02148.1 - 0.0025 17.5 10.4 0.0025 17.5 7.2 2.9 2 2 0 2 2 2 1 Right handed beta helix region ABC_tran PF00005.22 EOO02149.1 - 5.3e-50 169.2 0.4 7e-30 104.1 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EOO02149.1 - 3.3e-21 75.9 23.7 3.7e-20 72.4 3.4 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EOO02149.1 - 5.9e-07 29.7 1.6 0.3 10.9 0.0 4.4 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EOO02149.1 - 6.7e-07 28.7 1.0 0.017 14.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EOO02149.1 - 1.2e-05 25.2 0.9 0.1 12.5 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 EOO02149.1 - 1.3e-05 24.5 5.9 1.7 7.8 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 EOO02149.1 - 0.00019 21.9 1.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein ATP_bind_1 PF03029.12 EOO02149.1 - 0.00032 20.3 1.2 0.03 13.8 0.0 3.4 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EOO02149.1 - 0.00041 20.3 0.4 0.46 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EOO02149.1 - 0.00069 19.0 0.1 2 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EOO02149.1 - 0.0013 19.5 0.0 6.5 7.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EOO02149.1 - 0.0034 17.2 2.8 0.022 14.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 ArgK PF03308.11 EOO02149.1 - 0.02 13.6 1.9 1.9 7.1 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 EOO02149.1 - 0.025 14.8 9.9 0.48 10.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 EOO02149.1 - 0.025 13.6 1.7 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EOO02149.1 - 0.026 13.7 0.2 6.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EOO02149.1 - 0.028 13.8 1.2 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EOO02149.1 - 0.039 13.5 3.0 0.64 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EOO02149.1 - 0.043 12.7 0.1 4.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 EOO02149.1 - 0.056 12.3 0.6 3 6.6 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF2207 PF09972.4 EOO02149.1 - 0.26 9.8 3.0 0.22 10.0 0.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Dynamin_N PF00350.18 EOO02149.1 - 0.27 11.0 7.4 0.51 10.1 0.6 3.0 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.1 EOO02149.1 - 0.79 9.8 3.5 16 5.6 0.1 3.4 3 1 0 3 3 3 0 AAA domain Polysacc_deac_1 PF01522.16 EOO02150.1 - 2.1e-14 53.1 0.0 3.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DIOX_N PF14226.1 EOO02151.1 - 5.5e-29 101.0 0.1 7.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO02151.1 - 6.5e-24 84.0 0.0 1.6e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-bind_4 PF13837.1 EOO02152.1 - 0.044 13.9 0.1 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain VCBS PF13517.1 EOO02153.1 - 1.9e-35 121.0 53.9 2.2e-11 43.9 2.1 8.2 4 2 4 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO02153.1 - 3.3e-17 61.6 35.1 0.0039 16.8 0.0 8.1 8 0 0 8 8 8 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EOO02153.1 - 2.4e-13 49.9 11.1 0.09 12.2 0.0 6.5 3 2 3 6 6 6 6 Insecticide toxin TcdB middle/N-terminal region SUKH_5 PF14567.1 EOO02153.1 - 0.098 12.1 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall p450 PF00067.17 EOO02154.1 - 1.1e-39 136.2 0.0 1.4e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.9 EOO02157.1 - 5.9e-57 192.9 0.1 7.7e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RTA1 PF04479.8 EOO02158.1 - 5.4e-52 176.5 9.5 7.9e-52 175.9 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein SAD_SRA PF02182.12 EOO02159.1 - 6.6e-27 93.7 0.0 1e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain MFS_1 PF07690.11 EOO02160.1 - 4.4e-35 121.0 50.4 2.6e-34 118.5 34.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO02160.1 - 0.00016 20.4 16.4 0.00016 20.4 11.4 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter DUF917 PF06032.7 EOO02161.1 - 2.6e-106 355.1 0.6 4e-106 354.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EOO02161.1 - 1.8e-50 171.6 1.1 4.7e-49 167.0 0.7 2.2 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO02161.1 - 7.8e-10 38.5 0.5 2.6e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EOO02161.1 - 0.00067 18.6 0.2 0.39 9.6 0.0 2.3 2 0 0 2 2 2 2 StbA protein MreB_Mbl PF06723.8 EOO02161.1 - 0.0024 16.5 1.2 0.24 9.9 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein MutL PF13941.1 EOO02161.1 - 0.02 13.2 0.0 0.04 12.2 0.0 1.4 1 0 0 1 1 1 0 MutL protein adh_short_C2 PF13561.1 EOO02162.1 - 8.9e-36 123.8 0.0 1.1e-35 123.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO02162.1 - 7.8e-28 97.4 0.0 9.8e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02162.1 - 3.4e-09 36.6 0.0 4.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EOO02162.1 - 0.0033 16.4 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EOO02162.1 - 0.0062 15.9 0.0 0.029 13.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AA_permease_2 PF13520.1 EOO02163.1 - 7.4e-73 245.4 26.1 1.1e-72 244.9 18.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO02163.1 - 2.6e-18 65.6 22.1 3.9e-18 65.0 15.3 1.3 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.13 EOO02164.1 - 9e-21 74.1 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Sugar_tr PF00083.19 EOO02165.1 - 1.9e-110 369.5 19.0 2.2e-110 369.3 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02165.1 - 7.9e-25 87.3 25.0 1.3e-16 60.3 1.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EOO02165.1 - 0.0029 15.7 0.5 0.0049 14.9 0.4 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EOO02165.1 - 0.014 15.3 4.8 0.22 11.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Epimerase PF01370.16 EOO02166.1 - 9.6e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO02166.1 - 3.5e-09 36.9 1.6 2.9e-08 33.9 1.0 2.3 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EOO02166.1 - 9.2e-07 27.8 0.0 1.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EOO02166.1 - 6.5e-05 22.2 0.6 0.00018 20.8 0.4 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EOO02166.1 - 0.0014 18.5 3.9 0.06 13.2 2.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EOO02166.1 - 0.0084 15.0 0.1 0.47 9.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Herpes_heli_pri PF05774.6 EOO02166.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component KR PF08659.5 EOO02166.1 - 0.024 14.2 0.9 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 KR domain Glyco_hydro_18 PF00704.23 EOO02167.1 - 1.4e-43 149.6 3.9 2.4e-43 148.8 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EOO02167.1 - 8.1e-31 105.7 4.5 1e-30 105.4 1.4 2.7 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.14 EOO02167.1 - 0.00062 19.6 4.4 0.00062 19.6 3.0 3.3 3 0 0 3 3 3 1 Chitin recognition protein TauD PF02668.11 EOO02168.1 - 9.6e-41 140.1 0.1 1.6e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 EOO02169.1 - 5.3e-17 62.4 0.5 1.3e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO02169.1 - 2.5e-08 34.0 0.0 4.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_S10 PF00450.17 EOO02171.1 - 6.2e-40 137.6 1.1 7.8e-40 137.3 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 EOO02172.1 - 1.2 7.7 15.5 1.7 7.2 8.6 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily PrgI PF12666.2 EOO02172.1 - 1.9 8.7 7.0 0.26 11.4 1.0 2.1 1 1 1 2 2 2 0 PrgI family protein GFA PF04828.9 EOO02173.1 - 0.00053 19.8 0.1 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.17 EOO02174.1 - 4e-52 177.2 0.0 5.5e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 EOO02175.1 - 4.6e-96 321.6 0.0 5.3e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EOO02175.1 - 0.047 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyoxalase_2 PF12681.2 EOO02175.1 - 0.089 13.4 0.1 3.9 8.1 0.0 3.1 3 1 0 3 3 3 0 Glyoxalase-like domain Methyltransf_23 PF13489.1 EOO02176.1 - 3.7e-20 72.2 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO02176.1 - 1.6e-11 44.7 0.0 3.2e-10 40.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02176.1 - 3.1e-11 43.0 0.0 1.5e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO02176.1 - 4.1e-10 40.0 0.0 1.9e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO02176.1 - 8e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO02176.1 - 0.00048 19.2 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 EOO02176.1 - 0.00079 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EOO02176.1 - 0.0014 18.6 0.0 0.041 13.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO02176.1 - 0.0018 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO02176.1 - 0.0045 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EOO02176.1 - 0.0058 16.6 0.1 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EOO02176.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 EOO02176.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.15 EOO02176.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BUD22 PF09073.5 EOO02177.1 - 2.7e-71 240.8 29.7 3.8e-71 240.4 20.6 1.2 1 0 0 1 1 1 1 BUD22 Peptidase_M20 PF01546.23 EOO02178.1 - 1e-23 83.8 0.1 1.3e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EOO02178.1 - 2.2e-06 27.4 0.1 4.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EOO02178.1 - 0.0056 16.4 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 UCH_1 PF13423.1 EOO02179.1 - 1.3e-41 143.0 0.0 2.1e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EOO02179.1 - 1.9e-26 93.3 0.0 4.8e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EOO02179.1 - 0.0009 18.4 0.0 0.0053 15.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YojJ PF10372.4 EOO02179.1 - 0.053 13.3 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Filament PF00038.16 EOO02181.1 - 6.7e-10 38.9 143.4 0.0095 15.4 26.5 6.1 1 1 4 5 5 5 5 Intermediate filament protein AAA_13 PF13166.1 EOO02181.1 - 0.59 8.5 132.7 0.016 13.7 12.5 5.2 1 1 2 4 4 4 0 AAA domain SNF2_N PF00176.18 EOO02182.1 - 8.5e-76 254.5 0.0 8.4e-75 251.3 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EOO02182.1 - 4e-12 45.8 0.0 8.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EOO02182.1 - 0.0063 15.9 2.2 0.0089 15.4 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 RNase_H2-Ydr279 PF09468.5 EOO02182.1 - 0.92 8.6 8.5 0.8 8.8 1.7 2.5 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) CTP_synth_N PF06418.9 EOO02183.1 - 1.3e-118 395.0 1.5 2.1e-118 394.4 1.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EOO02183.1 - 3.8e-54 183.0 0.0 5.9e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EOO02183.1 - 2e-06 27.3 0.0 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EOO02183.1 - 0.00036 20.0 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.20 EOO02184.1 - 3.1e-10 40.2 0.0 5.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02184.1 - 0.00023 20.8 0.1 0.00041 20.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO02184.1 - 0.06 12.2 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.14 EOO02185.1 - 2.4e-10 40.0 0.4 6.8e-10 38.5 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EOO02185.1 - 0.00088 19.3 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EOO02185.1 - 0.028 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SE PF08491.5 EOO02185.1 - 0.028 13.2 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AATF-Che1 PF13339.1 EOO02186.1 - 7.6e-31 106.9 4.0 2.6e-30 105.2 2.8 2.0 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EOO02186.1 - 8.1e-31 105.9 0.1 8.1e-31 105.9 0.1 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Spc7 PF08317.6 EOO02187.1 - 0.00062 18.5 12.6 0.00077 18.2 8.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MerR-DNA-bind PF09278.6 EOO02187.1 - 0.037 14.4 1.1 0.037 14.4 0.7 3.1 2 1 1 3 3 3 0 MerR, DNA binding CDC37_N PF03234.9 EOO02187.1 - 0.16 12.2 11.7 0.13 12.6 7.0 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 EOO02187.1 - 2.5 7.0 10.8 3.3 6.6 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 EOO02187.1 - 2.9 7.6 20.1 15 5.3 13.9 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2992 PF11208.3 EOO02187.1 - 4 7.3 15.4 6 6.7 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) IncA PF04156.9 EOO02187.1 - 4.2 6.9 13.3 6.3 6.3 9.2 1.4 1 0 0 1 1 1 0 IncA protein DUF4537 PF15057.1 EOO02188.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Milton PF12448.3 EOO02188.1 - 0.012 15.8 0.5 0.012 15.8 0.4 1.9 2 0 0 2 2 2 0 Kinesin associated protein Aldolase_II PF00596.16 EOO02189.1 - 1.2e-20 73.8 0.0 3.7e-13 49.4 0.0 2.1 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain Chal_sti_synt_N PF00195.14 EOO02190.1 - 8.3e-23 80.8 0.1 1.3e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EOO02190.1 - 1.3e-20 73.8 0.0 2.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EOO02190.1 - 2.1e-05 23.7 0.0 4.2e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EOO02190.1 - 0.00019 21.3 0.0 0.00075 19.4 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EOO02190.1 - 0.00052 19.6 0.2 0.0083 15.7 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sugar_tr PF00083.19 EOO02191.1 - 4.3e-67 226.6 10.9 4.3e-67 226.6 7.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02191.1 - 8.7e-08 31.2 18.7 1.1e-06 27.6 7.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO02192.1 - 6.4e-87 292.0 22.2 7.7e-87 291.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02192.1 - 3.1e-26 91.9 30.5 8.1e-26 90.5 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO02192.1 - 4.5e-06 25.3 29.7 0.0023 16.3 9.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EOO02192.1 - 0.088 11.5 17.1 0.012 14.3 6.8 2.4 2 1 1 3 3 3 0 PUCC protein VHS PF00790.14 EOO02193.1 - 5.1e-35 120.1 0.4 1.2e-34 118.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 EOO02193.1 - 9.3e-17 60.3 0.2 2.1e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EOO02193.1 - 4.9e-16 57.8 0.1 1.3e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EOO02193.1 - 6.2e-16 57.6 0.0 1.3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 EOO02193.1 - 0.0057 16.5 2.0 0.015 15.2 0.5 2.2 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 EOO02193.1 - 0.041 13.4 4.9 0.14 11.7 3.4 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 EOO02193.1 - 0.96 8.8 4.4 0.17 11.3 0.3 1.7 2 0 0 2 2 2 0 TIR domain CK_II_beta PF01214.13 EOO02194.1 - 4.1e-76 254.5 0.0 6.9e-76 253.8 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit SET PF00856.23 EOO02196.1 - 6.5e-07 29.7 0.0 0.026 14.8 0.0 3.1 2 1 0 2 2 2 2 SET domain FTR1 PF03239.9 EOO02197.1 - 3.3e-85 285.7 3.8 3.9e-85 285.4 2.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 EOO02197.1 - 0.012 15.3 0.4 0.012 15.3 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) Tmemb_14 PF03647.8 EOO02197.1 - 0.73 10.2 7.8 1.4 9.3 0.1 3.0 3 0 0 3 3 3 0 Transmembrane proteins 14C NuA4 PF09340.5 EOO02198.1 - 0.012 15.2 1.7 0.022 14.3 1.2 1.6 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 HAND PF09110.6 EOO02198.1 - 0.35 11.2 7.0 0.7 10.3 4.9 1.6 1 1 0 1 1 1 0 HAND DUF3713 PF12506.3 EOO02198.1 - 1.1 9.4 3.4 4.2 7.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) Glyco_hydro_3_C PF01915.17 EOO02199.1 - 4.6e-60 202.9 0.0 1.4e-59 201.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EOO02199.1 - 3.3e-59 200.3 0.0 4.5e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EOO02199.1 - 3.2e-14 52.6 0.0 2e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EOO02199.1 - 3.8e-13 49.3 0.5 1.7e-12 47.2 0.1 2.1 2 0 0 2 2 2 1 PA14 domain Cupin_1 PF00190.17 EOO02201.1 - 5.5e-11 42.0 0.1 8.1e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Cupin RestrictionSfiI PF11487.3 EOO02201.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI RRM_1 PF00076.17 EOO02202.1 - 6.5e-09 35.2 0.0 1.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02202.1 - 6.5e-08 32.4 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EOO02202.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EOO02202.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Cu-oxidase_2 PF07731.9 EOO02203.1 - 1.1e-42 144.7 14.3 6.7e-39 132.5 2.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EOO02203.1 - 5.9e-39 132.4 9.1 2.8e-37 127.0 1.0 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EOO02203.1 - 2.5e-37 128.2 3.7 1.4e-33 116.0 0.5 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 EOO02203.1 - 0.0027 17.5 0.0 8.7 6.3 0.0 3.6 2 1 0 2 2 2 2 Cupredoxin-like domain COX2 PF00116.15 EOO02203.1 - 0.016 15.0 0.5 1.2 8.9 0.1 3.3 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, periplasmic domain LigB PF02900.13 EOO02204.1 - 2.9e-48 164.2 0.0 3.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.19 EOO02205.1 - 2.4e-31 108.8 27.4 3.7e-18 65.3 7.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO02205.1 - 1e-19 70.4 37.1 8.7e-12 44.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EOO02206.1 - 1.3e-22 80.5 0.5 6.4e-22 78.2 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO02206.1 - 1.9e-11 44.2 0.0 9.9e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO02206.1 - 4e-08 33.1 1.4 2e-07 30.8 0.3 2.0 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EOO02206.1 - 0.01 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EOO02206.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EOO02206.1 - 0.042 13.8 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 EOO02206.1 - 0.056 13.8 0.8 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 EOO02206.1 - 0.094 12.1 0.0 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GTP_EFTU PF00009.22 EOO02207.1 - 1.5e-44 151.6 0.0 2.6e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EOO02207.1 - 8.8e-21 73.9 0.6 2.4e-20 72.5 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EOO02207.1 - 3.3e-08 33.5 1.6 5.9e-08 32.7 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EOO02207.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EOO02207.1 - 0.08 11.6 0.4 0.15 10.7 0.3 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Mito_carr PF00153.22 EOO02208.1 - 2.5e-59 196.9 3.6 1.6e-20 72.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EOO02208.1 - 0.046 13.7 2.6 0.082 12.9 0.0 2.7 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family PEPCK_ATP PF01293.15 EOO02209.1 - 2.4e-215 715.4 0.0 2.8e-215 715.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EOO02209.1 - 0.0076 16.5 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EOO02209.1 - 0.077 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EOO02209.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EOO02209.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain BTB PF00651.26 EOO02210.1 - 3.7e-13 49.4 0.0 2.7e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain DUF106 PF01956.11 EOO02212.1 - 7.3 6.0 11.3 49 3.4 6.9 2.4 2 1 0 2 2 2 0 Integral membrane protein DUF106 PTPA PF03095.10 EOO02213.1 - 2.2e-113 378.4 0.0 2.6e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Mito_carr PF00153.22 EOO02214.1 - 4.1e-54 180.2 3.5 6.1e-19 67.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.15 EOO02214.1 - 0.045 13.3 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex ABC2_membrane PF01061.19 EOO02215.1 - 3.8e-83 277.7 57.9 4.5e-44 150.1 13.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EOO02215.1 - 7.5e-36 123.4 0.0 7.5e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EOO02215.1 - 1e-29 102.2 0.1 1.4e-26 92.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EOO02215.1 - 7.8e-08 32.2 0.0 2.4e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EOO02215.1 - 4.1e-07 29.6 0.1 0.0024 17.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EOO02215.1 - 2.5e-06 27.4 0.1 0.0049 16.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EOO02215.1 - 3.3e-06 27.8 0.0 0.01 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EOO02215.1 - 4.4e-06 26.8 0.0 0.03 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EOO02215.1 - 0.00014 21.2 0.2 0.0064 15.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EOO02215.1 - 0.00019 21.4 0.2 0.077 12.9 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EOO02215.1 - 0.00023 21.2 0.0 0.6 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EOO02215.1 - 0.00024 20.6 1.1 0.028 13.8 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EOO02215.1 - 0.00026 20.6 0.5 0.61 9.7 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EOO02215.1 - 0.00055 19.1 0.0 0.0024 17.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EOO02215.1 - 0.0011 19.0 0.1 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO02215.1 - 0.0013 18.4 0.6 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EOO02215.1 - 0.0023 18.2 0.0 0.51 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EOO02215.1 - 0.006 16.2 0.7 2.6 7.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EOO02215.1 - 0.0074 15.5 0.1 0.58 9.3 0.0 2.9 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EOO02215.1 - 0.02 15.3 0.0 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EOO02215.1 - 0.021 15.0 0.1 13 6.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EOO02215.1 - 0.041 13.3 1.3 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EOO02215.1 - 0.042 12.8 0.0 2.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 EOO02215.1 - 0.064 12.2 44.4 0.27 10.2 8.2 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein Arch_ATPase PF01637.13 EOO02215.1 - 0.077 12.6 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EOO02215.1 - 0.083 13.0 1.4 8.3 6.6 0.0 3.7 5 0 0 5 5 4 0 RNA helicase FtsK_SpoIIIE PF01580.13 EOO02215.1 - 0.12 11.8 0.2 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EOO02215.1 - 0.12 11.8 1.4 4.9 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 EOO02215.1 - 0.15 12.4 2.8 0.5 10.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EOO02215.1 - 0.16 11.5 0.6 7.6 6.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF3073 PF11273.3 EOO02215.1 - 1.8 9.1 4.6 0.5 10.9 0.2 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF3073) Pertussis_S1 PF02917.9 EOO02216.1 - 0.033 13.7 0.1 0.081 12.4 0.1 1.6 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 FAD-oxidase_C PF02913.14 EOO02218.1 - 7e-64 215.5 0.0 9.9e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EOO02218.1 - 9.8e-37 125.5 0.3 1.9e-36 124.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L7Ae PF01248.21 EOO02219.1 - 1.2e-28 98.4 0.9 1.5e-28 98.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EOO02219.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Zn_clus PF00172.13 EOO02220.1 - 2.2e-06 27.4 12.3 4.1e-06 26.5 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CH PF00307.26 EOO02221.1 - 4.7e-40 135.9 0.2 2.6e-19 69.2 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EOO02221.1 - 8.1e-27 92.9 0.0 2.7e-26 91.2 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EOO02221.1 - 3.7e-12 45.7 0.5 2.4e-07 30.2 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EOO02221.1 - 0.00075 19.1 0.1 0.0036 17.0 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.16 EOO02221.1 - 0.00081 19.6 3.9 0.31 11.3 1.1 2.7 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.1 EOO02221.1 - 0.0081 15.7 0.3 0.041 13.5 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EOO02221.1 - 0.039 13.2 0.0 0.13 11.6 0.0 2.0 1 0 0 1 1 1 0 EF hand Sipho_Gp157 PF05565.6 EOO02221.1 - 0.57 9.7 4.6 0.49 9.9 0.2 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Flavodoxin_5 PF12724.2 EOO02222.1 - 2.1e-17 63.4 0.0 2.9e-14 53.2 0.0 2.0 2 0 0 2 2 2 2 Flavodoxin domain Flavodoxin_1 PF00258.20 EOO02222.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin Flavodoxin_4 PF12682.2 EOO02222.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_3 PF12641.2 EOO02222.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain TCTP PF00838.12 EOO02223.1 - 1.2e-67 227.0 3.6 1.3e-67 226.9 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PPR_2 PF13041.1 EOO02224.1 - 1.4e-15 56.9 0.0 0.00013 21.8 0.0 4.1 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EOO02224.1 - 1.1e-14 53.3 2.1 0.0076 16.4 0.0 6.2 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 EOO02224.1 - 4.9e-08 32.4 2.5 0.028 14.3 0.0 5.3 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 EOO02224.1 - 0.00054 19.3 0.3 4 7.0 0.0 4.0 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.6 EOO02224.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) DnaB PF00772.16 EOO02224.1 - 0.061 13.1 0.1 3.2 7.6 0.0 2.6 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain DUF1722 PF08349.6 EOO02224.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) TPR_14 PF13428.1 EOO02224.1 - 0.17 12.5 0.4 19 6.2 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat ABM PF03992.11 EOO02225.1 - 0.00069 19.5 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SH3_1 PF00018.23 EOO02226.1 - 3.2e-06 26.4 0.0 6.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EOO02226.1 - 4e-05 23.1 0.1 6.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EOO02226.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Arginase PF00491.16 EOO02227.1 - 3.5e-90 302.0 0.0 4.2e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EOO02227.1 - 0.12 12.5 0.3 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 UPF0489 domain Lipase_3 PF01764.20 EOO02228.1 - 2.8e-08 33.4 0.1 6.3e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.7 EOO02228.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EOO02228.1 - 0.028 14.1 0.1 0.097 12.4 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family DIOX_N PF14226.1 EOO02229.1 - 1.6e-23 83.4 0.0 2.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO02229.1 - 6e-10 39.3 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAO PF01266.19 EOO02230.1 - 2.1e-19 69.6 0.0 1.5e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO02230.1 - 0.0002 21.2 0.2 0.00055 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EOO02230.1 - 0.00058 19.7 0.1 0.0093 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EOO02230.1 - 0.0082 15.9 0.1 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family FAD_binding_3 PF01494.14 EOO02230.1 - 0.0098 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EOO02230.1 - 0.018 13.9 0.2 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EOO02230.1 - 0.02 15.2 0.2 0.053 13.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO02230.1 - 0.059 12.4 0.1 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EOO02230.1 - 0.12 12.1 0.1 1.2 8.9 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EOO02230.1 - 0.12 11.1 0.0 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.24 EOO02231.1 - 1.6e-40 138.3 0.0 3.2e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO02231.1 - 1.3e-26 92.2 0.1 3.3e-26 90.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EOO02231.1 - 1.4e-05 24.0 0.0 3.2e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EOO02231.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S8 PF00410.14 EOO02232.1 - 3.4e-25 88.3 0.0 4.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-RING_2 PF13639.1 EOO02233.1 - 1.9e-08 33.9 5.1 2.8e-08 33.4 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EOO02233.1 - 2.1e-08 33.6 4.7 6.9e-08 32.0 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO02233.1 - 1.8e-07 31.0 3.5 5e-07 29.6 2.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02233.1 - 5.8e-07 29.1 2.0 1.2e-06 28.0 1.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EOO02233.1 - 8.2e-07 28.7 2.3 8.5e-07 28.6 0.2 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EOO02233.1 - 3.1e-06 26.7 0.6 5.9e-06 25.8 0.4 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EOO02233.1 - 3.1e-05 23.7 5.8 0.00012 21.8 4.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EOO02233.1 - 0.00012 21.7 1.1 0.00024 20.7 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EOO02233.1 - 0.8 9.8 5.5 8.2 6.6 4.0 2.4 1 1 1 2 2 2 0 RING-H2 zinc finger PUF PF00806.14 EOO02234.1 - 3.7e-64 208.7 11.5 1.3e-08 33.8 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 EOO02234.1 - 0.19 11.8 2.1 6.3 6.9 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF2346 PF09803.4 EOO02235.1 - 0.00049 19.8 6.4 0.0013 18.5 4.4 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) MscS_TM PF12794.2 EOO02235.1 - 9.8 4.6 6.9 13 4.2 4.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 His_Phos_2 PF00328.17 EOO02236.1 - 2.7e-24 86.1 0.0 1.3e-22 80.6 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.19 EOO02237.1 - 2.4e-57 194.4 15.4 2e-35 122.2 4.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO02237.1 - 0.00018 20.3 20.4 0.0014 17.4 14.4 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily tRNA-synt_2b PF00587.20 EOO02238.1 - 5.2e-65 218.2 0.0 9.6e-65 217.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EOO02238.1 - 3.4e-19 68.5 0.0 1.2e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain Amidohydro_2 PF04909.9 EOO02239.1 - 1.2e-11 44.6 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase PGAP1 PF07819.8 EOO02239.1 - 3.9e-05 23.3 0.0 8.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EOO02239.1 - 0.00058 19.5 0.0 0.066 12.7 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO02239.1 - 0.0017 18.2 1.9 0.0051 16.7 1.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02239.1 - 0.0031 17.2 3.1 0.0079 15.9 1.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EOO02239.1 - 0.0036 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EOO02239.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TatD_DNase PF01026.16 EOO02239.1 - 0.072 12.2 0.0 0.92 8.6 0.0 2.1 2 0 0 2 2 2 0 TatD related DNase DUF676 PF05057.9 EOO02239.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EOO02239.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DnaJ PF00226.26 EOO02242.1 - 5.4e-08 32.4 0.1 1.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Draxin PF15550.1 EOO02242.1 - 1.9 8.0 19.4 2.7 7.5 13.5 1.2 1 0 0 1 1 1 0 Draxin Ebola_NP PF05505.7 EOO02242.1 - 2.7 5.9 12.6 3.3 5.6 8.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Hanta_nucleocap PF00846.13 EOO02242.1 - 9.2 4.8 10.0 15 4.1 6.8 1.4 1 1 0 1 1 1 0 Hantavirus nucleocapsid protein Paf1 PF03985.8 EOO02243.1 - 6.1e-48 163.6 0.0 7.9e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Paf1 Pkinase PF00069.20 EOO02244.1 - 1.8e-60 204.3 0.0 2.1e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02244.1 - 2.5e-36 125.0 0.0 3.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02244.1 - 2.2e-08 33.4 0.0 3.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EOO02244.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BUD22 PF09073.5 EOO02245.1 - 7.9 5.4 20.2 9.9 5.1 14.0 1.1 1 0 0 1 1 1 0 BUD22 WD40 PF00400.27 EOO02246.1 - 1.4e-24 84.9 14.5 1.5e-07 31.0 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EOO02246.1 - 0.061 12.0 0.1 0.25 10.0 0.0 1.9 2 1 1 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.1 EOO02246.1 - 0.078 13.2 2.7 51 4.3 0.0 4.7 5 2 0 5 5 5 0 PQQ-like domain PQQ PF01011.16 EOO02246.1 - 0.21 11.1 1.2 18 5.0 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat FA_hydroxylase PF04116.8 EOO02247.1 - 3e-16 59.8 14.6 3e-16 59.8 10.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Leu_Phe_trans PF03588.9 EOO02247.1 - 0.15 11.2 1.6 0.99 8.5 0.0 2.2 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase DUF1640 PF07798.6 EOO02248.1 - 7.5e-14 52.1 3.6 1.2e-13 51.5 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 EOO02248.1 - 0.00038 19.3 0.1 0.00066 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Baculo_PEP_C PF04513.7 EOO02248.1 - 0.11 12.3 5.1 0.2 11.5 3.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RR_TM4-6 PF06459.7 EOO02248.1 - 0.39 10.5 10.0 1.2 9.0 6.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CRAL_TRIO PF00650.15 EOO02249.1 - 1.8e-42 144.5 0.0 2.4e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EOO02249.1 - 2.3e-11 43.6 1.0 2.3e-11 43.6 0.7 2.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EOO02249.1 - 0.006 16.4 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2283 PF10049.4 EOO02249.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) TruD PF01142.13 EOO02250.1 - 1.6e-49 168.5 0.0 2e-46 158.3 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Proteasome PF00227.21 EOO02251.1 - 1.1e-55 187.8 0.1 1.6e-55 187.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EOO02251.1 - 2e-05 23.7 0.1 2e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DAO PF01266.19 EOO02252.1 - 7.4e-10 38.2 0.0 8.8e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HEAT_2 PF13646.1 EOO02253.1 - 9.7e-13 48.2 5.9 0.0073 16.5 0.0 6.3 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EOO02253.1 - 9.7e-07 28.3 14.9 0.17 12.0 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EOO02253.1 - 0.00012 22.3 0.0 0.099 13.0 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Resolvase PF00239.16 EOO02253.1 - 0.039 13.8 0.4 0.35 10.7 0.0 2.9 3 0 0 3 3 3 0 Resolvase, N terminal domain Ribosomal_L19 PF01245.15 EOO02254.1 - 6.3e-19 67.8 0.2 1.1e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Rer1 PF03248.8 EOO02255.1 - 8.7e-75 250.1 7.2 1.6e-65 219.9 1.6 2.0 2 0 0 2 2 2 2 Rer1 family FUSC_2 PF13515.1 EOO02255.1 - 1.6 8.6 10.3 7.4 6.5 7.1 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein-like AAA_5 PF07728.9 EOO02256.1 - 2.8e-10 40.0 0.0 4.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EOO02256.1 - 1.2e-06 28.5 0.0 5.5e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EOO02256.1 - 1.3e-06 28.5 0.0 3e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO02256.1 - 9.7e-05 23.1 0.3 0.039 14.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 EOO02256.1 - 0.00046 20.0 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EOO02256.1 - 0.00051 20.0 0.1 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain Sigma54_activat PF00158.21 EOO02256.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EOO02256.1 - 0.0066 15.6 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EOO02256.1 - 0.013 15.6 0.1 0.073 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EOO02256.1 - 0.039 14.2 0.4 0.19 12.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EOO02256.1 - 0.091 12.4 0.0 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 EOO02256.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Rotamase PF00639.16 EOO02259.1 - 6.5e-17 62.0 2.1 7.2e-17 61.9 0.8 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EOO02259.1 - 3.6e-15 56.2 1.0 3.6e-15 56.2 0.7 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EOO02259.1 - 5.4e-05 23.8 0.9 8.1e-05 23.2 0.6 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain YL1_C PF08265.6 EOO02260.1 - 3.4e-15 55.2 1.2 5.1e-15 54.7 0.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 EOO02260.1 - 0.032 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger PTPLA PF04387.9 EOO02261.1 - 7.3e-47 158.8 7.5 7.3e-47 158.8 5.2 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA P12 PF12669.2 EOO02261.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family CCSMST1 PF15013.1 EOO02261.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.0 3 0 0 3 3 3 0 CCSMST1 family PALP PF00291.20 EOO02263.1 - 1.2e-59 202.0 0.1 1.5e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sulfatase PF00884.18 EOO02264.1 - 6.1e-28 97.8 0.0 8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EOO02264.1 - 0.001 17.5 0.0 0.0018 16.8 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4259 PF14078.1 EOO02265.1 - 0.015 15.7 0.1 0.036 14.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) ECH PF00378.15 EOO02266.1 - 6.5e-71 238.3 0.0 8.1e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Thg1 PF04446.7 EOO02266.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase Pol_alpha_B_N PF08418.5 EOO02267.1 - 2.2e-52 178.1 0.5 2.1e-29 102.8 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EOO02267.1 - 5.8e-31 107.3 0.1 9.4e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Transcrip_reg PF01709.15 EOO02268.1 - 8.4e-50 169.0 0.2 9.4e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator dCMP_cyt_deam_2 PF08211.6 EOO02268.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region HTH_psq PF05225.11 EOO02268.1 - 0.4 10.2 0.1 0.4 10.2 0.0 2.5 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Catalase PF00199.14 EOO02269.1 - 2.5e-162 539.9 3.8 9.2e-90 301.0 0.9 2.3 2 1 1 3 3 3 2 Catalase Catalase-rel PF06628.7 EOO02269.1 - 1.8e-12 46.8 0.0 3.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF865 PF05906.6 EOO02269.1 - 1.1 8.8 4.2 0.55 9.8 0.4 2.3 3 0 0 3 3 3 0 Herpesvirus-7 repeat of unknown function (DUF865) Lipase_GDSL_2 PF13472.1 EOO02270.1 - 4.9e-14 52.8 0.0 1.2e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Glyco_transf_90 PF05686.7 EOO02271.1 - 1.5e-12 46.9 8.6 1.5e-11 43.5 6.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 GCV_T PF01571.16 EOO02272.1 - 1.8e-14 53.6 0.0 2.2e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EOO02272.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain zf-CHY PF05495.7 EOO02273.1 - 8.5e-09 35.4 15.7 1.1e-08 35.0 10.9 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EOO02273.1 - 0.13 12.1 13.0 1.5 8.6 6.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 EOO02273.1 - 0.58 9.8 13.2 1 9.0 9.1 1.3 1 0 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 EOO02273.1 - 1.7 8.3 10.5 0.24 11.0 3.7 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EOO02273.1 - 1.8 8.5 13.1 2.7 8.0 5.7 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF3797 PF12677.2 EOO02273.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) RNHCP PF12647.2 EOO02273.1 - 2.3 8.0 8.7 1.1 9.1 3.2 2.2 2 1 0 2 2 2 0 RNHCP domain C1_4 PF07975.7 EOO02273.1 - 3.6 7.6 15.5 9.5 6.3 5.7 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain Evr1_Alr PF04777.8 EOO02273.1 - 5.2 7.0 10.8 56 3.7 7.4 2.5 1 1 1 2 2 2 0 Erv1 / Alr family Skp1 PF01466.14 EOO02274.1 - 1.3e-39 134.0 1.1 2.6e-39 133.1 0.8 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EOO02274.1 - 5.8e-23 80.7 0.0 1.3e-22 79.6 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EOO02274.1 - 0.12 12.3 1.6 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Mis12 PF05859.7 EOO02275.1 - 1e-41 142.1 0.0 1.6e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Arf PF00025.16 EOO02276.1 - 1.5e-58 196.8 0.2 4e-57 192.2 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EOO02276.1 - 3.9e-08 32.3 0.1 9e-08 31.2 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EOO02276.1 - 2.2e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EOO02276.1 - 5.4e-06 25.7 0.0 6.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EOO02276.1 - 1.7e-05 24.0 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EOO02276.1 - 0.00018 21.9 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EOO02276.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EOO02276.1 - 0.017 13.8 0.1 0.033 12.9 0.1 1.4 1 1 0 1 1 1 0 ArgK protein DUF3986 PF13143.1 EOO02276.1 - 0.083 13.3 0.2 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Helicase_C_3 PF13625.1 EOO02277.1 - 8.6e-26 90.2 0.0 4.1e-24 84.7 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO02277.1 - 8.9e-17 61.5 0.1 7.1e-16 58.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EOO02277.1 - 6.2e-11 42.0 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EOO02277.1 - 2.3e-10 39.7 0.1 3.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EOO02277.1 - 3.9e-06 26.4 0.0 2.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Gluconate_2-dh3 PF13618.1 EOO02277.1 - 0.057 13.5 0.5 0.17 11.9 0.0 2.1 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 YL1 PF05764.8 EOO02278.1 - 4.8e-62 209.7 29.7 4.8e-62 209.7 20.6 2.4 3 0 0 3 3 3 1 YL1 nuclear protein GNVR PF13807.1 EOO02279.1 - 0.014 15.0 0.5 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase GIDE PF12483.3 EOO02279.1 - 0.14 11.5 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase Pyr_redox_2 PF07992.9 EOO02280.1 - 2.4e-31 109.1 0.0 6.4e-31 107.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO02280.1 - 2.5e-25 88.6 0.6 1.5e-20 73.3 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EOO02280.1 - 2.7e-22 78.8 0.0 6.6e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 EOO02280.1 - 5.4e-10 39.6 0.1 3.1e-05 24.1 0.1 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO02280.1 - 4.9e-06 25.2 1.0 0.0095 14.4 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 EOO02280.1 - 8.4e-06 24.9 0.0 0.047 12.5 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EOO02280.1 - 1.1e-05 25.1 0.1 0.065 12.8 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EOO02280.1 - 4e-05 22.6 4.5 0.031 13.1 0.1 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EOO02280.1 - 4.4e-05 22.7 0.5 0.2 10.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EOO02280.1 - 0.00038 19.4 2.2 0.0026 16.6 0.5 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EOO02280.1 - 0.00059 19.8 1.5 0.14 12.2 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EOO02280.1 - 0.00071 18.5 0.3 0.091 11.5 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EOO02280.1 - 0.00087 18.4 0.2 0.46 9.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EOO02280.1 - 0.00094 18.6 0.2 0.24 10.7 0.0 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 EOO02280.1 - 0.0043 16.1 0.2 0.024 13.7 0.0 2.3 2 1 1 3 3 3 1 Thi4 family XdhC_C PF13478.1 EOO02280.1 - 0.0061 16.8 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EOO02280.1 - 0.009 15.5 0.1 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EOO02280.1 - 0.042 13.0 0.2 0.37 9.9 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EOO02280.1 - 0.043 13.5 0.1 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EOO02280.1 - 0.056 13.4 0.4 11 6.0 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 EOO02280.1 - 0.078 13.2 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Rubella_E2 PF05749.6 EOO02280.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 F420_oxidored PF03807.12 EOO02280.1 - 0.55 10.7 2.8 7.7 7.0 0.2 3.3 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Prp19_bind PF06991.6 EOO02281.1 - 2.7e-48 164.6 40.6 2.7e-48 164.6 28.2 2.4 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain Ras PF00071.17 EOO02282.1 - 1.7e-52 177.0 0.0 2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO02282.1 - 4.7e-16 59.3 0.0 1.2e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EOO02282.1 - 1.6e-06 27.4 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EOO02283.1 - 1.3e-08 34.7 0.6 6.9e-08 32.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EOO02283.1 - 1.2e-06 27.7 0.0 3.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EOO02283.1 - 6.1e-05 22.8 1.9 0.048 13.4 0.0 3.0 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 EOO02283.1 - 0.00015 20.9 0.0 0.43 9.6 0.0 2.5 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.1 EOO02283.1 - 0.0014 18.0 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EOO02283.1 - 0.0015 18.0 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EOO02283.1 - 0.0016 18.7 5.6 0.15 12.3 0.0 4.0 4 1 0 4 4 4 1 ABC transporter Septin PF00735.13 EOO02283.1 - 0.0029 16.6 0.2 0.011 14.7 0.2 2.0 1 1 0 1 1 1 1 Septin T2SE PF00437.15 EOO02283.1 - 0.003 16.4 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EOO02283.1 - 0.0046 16.6 2.0 0.04 13.6 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_16 PF13191.1 EOO02283.1 - 0.0057 16.6 0.0 0.066 13.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.8 EOO02283.1 - 0.0064 15.3 0.0 0.017 13.9 0.0 1.7 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.22 EOO02283.1 - 0.0079 15.6 0.3 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EOO02283.1 - 0.0082 16.4 0.2 0.0082 16.4 0.1 3.2 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EOO02283.1 - 0.016 15.7 0.0 0.21 12.1 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_22 PF13401.1 EOO02283.1 - 0.023 14.8 0.0 0.37 10.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 EOO02284.1 - 3e-71 239.9 0.0 4.7e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EOO02284.1 - 9.9e-08 31.7 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain OmpH PF03938.9 EOO02284.1 - 0.0024 17.8 1.4 0.0037 17.1 0.9 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) KfrA_N PF11740.3 EOO02284.1 - 0.024 15.0 3.9 0.057 13.8 2.7 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Nup35_RRM_2 PF14605.1 EOO02284.1 - 0.086 12.6 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif tRNA_anti_2 PF13742.1 EOO02284.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain V_ATPase_I PF01496.14 EOO02284.1 - 0.16 9.7 0.3 0.24 9.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2681 PF10883.3 EOO02284.1 - 5 7.3 8.2 12 6.2 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Phosphodiest PF01663.17 EOO02285.1 - 5.1e-14 52.3 0.2 8.3e-14 51.6 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EOO02285.1 - 1.7e-05 24.3 0.2 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EOO02285.1 - 9e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF3445 PF11927.3 EOO02286.1 - 8.7e-64 215.2 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ank_2 PF12796.2 EOO02287.1 - 3.4e-17 62.5 0.1 2.6e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EOO02287.1 - 5.7e-14 51.1 0.4 3.6e-06 26.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EOO02287.1 - 6e-10 38.3 0.0 0.12 12.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EOO02287.1 - 1.4e-09 38.1 0.0 0.0016 18.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO02287.1 - 1.4e-07 31.5 0.9 3.2e-05 24.0 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.2 EOO02287.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EOO02287.1 - 0.0026 17.3 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain Glyco_hydro_7 PF00840.15 EOO02288.1 - 1.7e-194 646.1 20.5 2e-194 645.9 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 MFS_1 PF07690.11 EOO02290.1 - 4.2e-27 94.7 34.8 4.2e-27 94.7 24.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily CVNH PF08881.5 EOO02294.1 - 3.2e-18 65.8 0.1 3.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Glyco_hydro_31 PF01055.21 EOO02295.1 - 5.7e-111 371.4 1.0 6.9e-111 371.1 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EOO02295.1 - 1e-15 57.3 0.1 5.2e-15 55.0 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Cation_ATPase_C PF00689.16 EOO02296.1 - 1.1e-44 152.1 8.7 1.1e-44 152.1 6.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.15 EOO02296.1 - 2.8e-24 85.4 1.1 7.8e-24 83.9 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EOO02296.1 - 9.8e-24 84.9 0.6 2.9e-23 83.4 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO02296.1 - 4.1e-18 65.1 0.0 1.1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EOO02296.1 - 4.4e-14 51.6 0.1 5.2e-13 48.2 0.1 2.5 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EOO02296.1 - 2.2e-10 40.9 0.0 3.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO02296.1 - 1.6e-05 24.5 0.2 8.8e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EOO02296.1 - 0.0031 17.4 0.2 0.4 10.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) Gemini_mov PF01708.11 EOO02296.1 - 0.054 13.0 0.2 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein SpoA PF01052.15 EOO02296.1 - 0.059 12.9 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Surface presentation of antigens (SPOA) NDUF_B8 PF05821.6 EOO02297.1 - 8.5e-06 25.5 0.1 1.1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) FAD_binding_4 PF01565.18 EOO02298.1 - 4.2e-21 74.8 3.5 9.4e-21 73.7 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EOO02298.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like AAA PF00004.24 EOO02299.1 - 4.2e-18 65.8 0.0 2.1e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EOO02299.1 - 0.00082 19.4 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EOO02299.1 - 0.0022 18.1 0.6 0.061 13.4 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 EOO02299.1 - 0.0028 17.3 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EOO02299.1 - 0.0041 16.6 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EOO02299.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EOO02299.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EOO02299.1 - 0.15 12.2 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Tim54 PF11711.3 EOO02299.1 - 0.2 10.2 4.1 0.31 9.5 2.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MFS_1 PF07690.11 EOO02300.1 - 3.5e-29 101.6 24.4 3.5e-29 101.6 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SecE PF00584.15 EOO02300.1 - 0.0063 16.0 5.0 0.044 13.3 0.0 3.1 3 0 0 3 3 3 2 SecE/Sec61-gamma subunits of protein translocation complex p450 PF00067.17 EOO02301.1 - 8.6e-43 146.5 0.0 2.6e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 YqgB PF11036.3 EOO02301.1 - 0.0089 15.5 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Virulence promoting factor MFS_1 PF07690.11 EOO02302.1 - 1.4e-29 102.9 28.0 3.6e-29 101.5 19.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EOO02303.1 - 8.6e-29 100.3 23.3 2.3e-27 95.6 15.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4386 PF14329.1 EOO02303.1 - 0.011 15.2 2.2 0.011 15.2 1.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4386) Sugar_tr PF00083.19 EOO02304.1 - 4.2e-90 302.5 25.0 4.7e-90 302.3 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02304.1 - 4.8e-29 101.1 25.1 4.8e-29 101.1 17.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 EOO02304.1 - 0.11 12.1 3.3 0.37 10.4 2.3 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1049 PF06305.6 EOO02304.1 - 0.91 9.0 4.8 2.1 7.9 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) PD40 PF07676.7 EOO02305.1 - 1.9e-15 56.1 0.4 1.2e-06 28.0 0.0 3.5 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EOO02305.1 - 0.0001 21.0 0.0 0.0095 14.5 0.0 2.9 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EOO02305.1 - 0.0034 17.1 0.0 0.16 11.6 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.27 EOO02306.1 - 7.9e-29 96.7 7.5 1.2e-09 36.7 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EOO02306.1 - 1.3e-23 82.3 9.4 1.2e-13 50.4 0.5 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EOO02306.1 - 8.6e-22 77.0 6.7 6.3e-18 64.6 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EOO02306.1 - 1.2e-21 75.0 2.4 2.1e-07 29.9 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EOO02306.1 - 3.4e-19 66.9 5.1 1.1e-08 34.2 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.4 EOO02306.1 - 7.4e-07 29.1 0.5 1.7e-05 24.7 0.1 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EOO02306.1 - 3.4e-06 26.7 3.2 0.0022 17.6 0.3 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EOO02306.1 - 7e-05 22.6 0.7 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 EOO02306.1 - 0.02 14.8 0.4 0.05 13.5 0.1 1.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand TerB PF05099.8 EOO02306.1 - 0.02 14.6 0.6 0.058 13.1 0.1 1.7 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF3349 PF11829.3 EOO02306.1 - 0.032 14.6 0.1 0.094 13.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Mst1_SARAH PF11629.3 EOO02306.1 - 0.038 13.7 1.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1880 PF08976.6 EOO02306.1 - 0.062 13.4 0.0 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) VCBS PF13517.1 EOO02306.1 - 5.6 7.4 7.7 41 4.6 5.3 2.4 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Cu_amine_oxid PF01179.15 EOO02307.1 - 1.3e-114 383.1 6.6 1.6e-114 382.8 4.6 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EOO02307.1 - 6.1e-40 134.9 0.3 1.3e-39 133.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EOO02307.1 - 0.027 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain DEPP PF15343.1 EOO02307.1 - 0.21 11.1 0.1 0.55 9.8 0.0 1.6 2 0 0 2 2 2 0 Decidual protein induced by progesterone family Aminotran_3 PF00202.16 EOO02308.1 - 6.2e-93 311.3 0.0 7.6e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EOO02308.1 - 0.056 12.3 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II ComZ PF10815.3 EOO02308.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ComZ Isochorismatase PF00857.15 EOO02309.1 - 1.4e-18 67.4 0.0 1.7e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PK_C PF02887.11 EOO02309.1 - 0.01 15.3 0.0 0.027 14.0 0.0 1.8 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain FAD_binding_2 PF00890.19 EOO02310.1 - 1.7e-91 307.1 0.0 1.9e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EOO02310.1 - 4.9e-06 26.4 0.1 2.2e-05 24.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EOO02310.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EOO02310.1 - 2.8e-05 23.3 0.3 0.00026 20.1 0.0 2.5 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EOO02310.1 - 0.00013 20.9 0.1 0.0007 18.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EOO02310.1 - 0.00065 18.6 0.7 0.001 18.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EOO02310.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO02310.1 - 0.0017 18.2 0.0 0.017 15.0 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO02310.1 - 0.01 14.3 4.3 0.069 11.6 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 EOO02310.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EOO02310.1 - 0.03 13.2 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EOO02310.1 - 0.057 12.4 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EOO02311.1 - 2.7e-13 49.3 39.5 1.1e-12 47.3 24.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO02311.1 - 1.7e-07 29.8 16.5 2.5e-07 29.3 11.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M28 PF04389.12 EOO02312.1 - 5.6e-30 104.4 0.0 9.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EOO02312.1 - 2.1e-11 43.3 0.0 1.7e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EOO02312.1 - 0.00036 20.0 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EOO02312.1 - 0.16 10.6 0.0 0.74 8.5 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase p450 PF00067.17 EOO02313.1 - 2.2e-70 237.5 0.0 2.4e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.1 EOO02314.1 - 0.51 9.7 4.9 0.083 12.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) COX14 PF14880.1 EOO02314.1 - 0.68 9.6 0.0 0.68 9.6 0.0 2.4 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Jiraiya PF15038.1 EOO02314.1 - 1.3 8.4 6.5 0.092 12.1 0.9 1.7 2 0 0 2 2 2 0 Jiraiya Aldo_ket_red PF00248.16 EOO02315.1 - 5.4e-35 120.5 0.0 6.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EOO02316.1 - 1e-35 123.1 50.5 4.4e-35 121.0 34.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO02316.1 - 2.3e-14 52.8 10.9 2.3e-14 52.8 7.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter 2-Hacid_dh_C PF02826.14 EOO02317.1 - 3.7e-56 189.0 0.1 4.8e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EOO02317.1 - 4.6e-28 97.3 0.0 5.7e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EOO02317.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EOO02317.1 - 0.01 15.7 0.1 0.033 14.0 0.0 1.8 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.14 EOO02317.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase IlvN PF07991.7 EOO02317.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF2205 PF10224.4 EOO02319.1 - 1e-31 108.2 0.6 1.5e-31 107.7 0.4 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 EOO02319.1 - 0.026 13.2 0.2 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain YtxH PF12732.2 EOO02319.1 - 0.031 14.6 0.3 0.045 14.1 0.2 1.3 1 0 0 1 1 1 0 YtxH-like protein DUF3450 PF11932.3 EOO02319.1 - 0.1 11.8 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glyco_hydro_11 PF00457.12 EOO02320.1 - 8.2e-79 263.2 23.0 9.6e-79 262.9 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SNF2_N PF00176.18 EOO02321.1 - 4.2e-75 252.3 0.8 6.1e-75 251.7 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EOO02321.1 - 6.9e-14 51.4 0.1 1.9e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EOO02321.1 - 2.5e-05 23.9 7.2 9.8e-05 22.0 5.0 2.1 1 0 0 1 1 1 1 HSA HDA2-3 PF11496.3 EOO02321.1 - 0.00029 19.7 0.4 0.31 9.8 0.0 2.8 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DUF4038 PF13204.1 EOO02323.1 - 4.3e-53 180.5 3.4 2e-34 119.2 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) MFS_1 PF07690.11 EOO02324.1 - 2.4e-08 33.0 18.2 2.9e-08 32.8 12.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EOO02324.1 - 0.00043 18.9 5.3 0.00048 18.7 3.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like NAD_binding_2 PF03446.10 EOO02326.1 - 1.6e-31 109.3 0.6 2.6e-31 108.6 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EOO02326.1 - 3.8e-24 85.0 0.2 1.1e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EOO02326.1 - 4.6e-08 32.1 0.3 6.7e-08 31.6 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EOO02326.1 - 0.00011 22.4 0.1 0.00029 21.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1442 PF07279.6 EOO02326.1 - 0.088 11.9 0.1 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) DUF3094 PF11293.3 EOO02327.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) GFA PF04828.9 EOO02328.1 - 4.9e-17 61.6 0.9 7.4e-17 61.0 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EOO02328.1 - 0.071 12.8 0.4 0.071 12.8 0.3 2.9 3 0 0 3 3 3 0 Nudix N-terminal DUF2197 PF09963.4 EOO02328.1 - 0.16 11.9 0.3 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Cys_rich_CWC PF14375.1 EOO02328.1 - 0.94 9.4 7.5 0.73 9.8 2.8 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC DUF1272 PF06906.6 EOO02328.1 - 3.6 7.5 7.6 7.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Sugar_tr PF00083.19 EOO02329.1 - 2e-76 257.4 13.3 2.7e-75 253.6 9.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02329.1 - 1.7e-14 53.3 20.2 1e-13 50.7 11.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Exo_endo_phos PF03372.18 EOO02330.1 - 8.9e-09 35.6 0.2 1.4e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EOO02330.1 - 0.028 14.0 0.1 7.2 6.2 0.0 3.2 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Lactamase_B PF00753.22 EOO02331.1 - 6.4e-06 25.9 7.7 4.9e-05 23.0 5.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EOO02331.1 - 3.3e-05 23.5 0.1 5.6e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ADH_zinc_N PF00107.21 EOO02332.1 - 8.5e-21 73.8 0.0 1.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO02332.1 - 4.1e-08 34.1 0.0 7.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.16 EOO02333.1 - 6.1e-28 96.9 0.0 8.6e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EOO02333.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Sulfatase PF00884.18 EOO02334.1 - 5.6e-46 157.1 0.0 7.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EOO02334.1 - 0.0017 16.8 0.0 0.0024 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EOO02334.1 - 0.07 13.4 0.3 1 9.6 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 EOO02335.1 - 2e-113 379.3 25.4 2.9e-113 378.8 17.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02335.1 - 7.5e-26 90.6 36.4 1e-20 73.8 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 EOO02335.1 - 0.044 13.4 0.4 0.18 11.5 0.2 2.0 1 0 0 1 1 1 0 Lysis protein S PALP PF00291.20 EOO02336.1 - 4.4e-74 249.4 0.7 5.9e-74 249.0 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EOO02336.1 - 3.6e-37 125.8 0.0 2e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Fungal_trans_2 PF11951.3 EOO02337.1 - 3.5e-10 39.0 0.0 4.3e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 EOO02340.1 - 9.7e-72 241.6 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO02340.1 - 2e-12 47.8 0.1 8.9e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FKBP_C PF00254.23 EOO02341.1 - 2.4e-33 114.0 0.0 5.2e-33 112.9 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIG-S PF10510.4 EOO02342.1 - 8e-149 496.6 0.0 9.2e-149 496.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Pro_CA PF00484.14 EOO02343.1 - 1.1e-26 93.7 0.0 1.8e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase SGL PF08450.7 EOO02343.1 - 0.00036 19.9 1.5 0.033 13.5 0.1 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Polysacc_synt_4 PF04669.8 EOO02344.1 - 6.3e-27 94.1 1.4 3.3e-26 91.8 1.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Elongin_A PF06881.6 EOO02344.1 - 0.021 15.1 0.5 0.034 14.5 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2491 PF10679.4 EOO02344.1 - 0.054 12.4 0.6 0.06 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Rota_NSP4 PF01452.11 EOO02344.1 - 0.72 9.1 3.1 0.71 9.1 0.5 1.9 2 0 0 2 2 2 0 Rotavirus non structural protein Abhydrolase_5 PF12695.2 EOO02345.1 - 1.1e-07 31.7 0.0 7.9e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EOO02345.1 - 0.0011 18.2 0.1 0.022 13.9 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EOO02345.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EOO02345.1 - 0.024 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ycf1 PF05758.7 EOO02345.1 - 0.095 10.4 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Transp_cyt_pur PF02133.10 EOO02346.1 - 5.9e-20 71.2 31.8 5.6e-18 64.7 21.8 2.9 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PC_rep PF01851.17 EOO02347.1 - 6.2e-42 139.5 14.7 5.3e-08 32.6 0.0 9.1 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EOO02347.1 - 1.5e-17 63.6 0.0 3.1e-12 46.5 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EOO02347.1 - 8.2e-09 34.8 1.0 0.81 9.9 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EOO02347.1 - 2.8e-07 30.8 1.4 0.00017 21.9 0.0 4.6 4 1 0 4 4 4 1 HEAT-like repeat DUF3506 PF12014.3 EOO02348.1 - 4.6e-46 155.9 0.0 7.9e-46 155.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EOO02348.1 - 7.9e-09 35.1 2.0 1.4e-08 34.3 1.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EOO02348.1 - 1.7e-07 30.7 1.3 3.4e-07 29.7 0.9 1.5 1 0 0 1 1 1 1 F-box domain DUF3760 PF12586.3 EOO02348.1 - 0.037 13.8 0.2 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Elongin_A PF06881.6 EOO02348.1 - 0.075 13.4 0.1 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Myb_DNA-bind_6 PF13921.1 EOO02349.1 - 8.1e-05 22.6 0.6 0.00016 21.7 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1769 PF08588.5 EOO02350.1 - 3.8e-29 100.4 0.4 2.6e-28 97.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Asparaginase PF00710.15 EOO02351.1 - 8.1e-40 136.6 0.0 9.8e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Asparaginase DnaJ-X PF14308.1 EOO02352.1 - 5.1e-72 241.4 1.5 5.1e-72 241.4 1.0 2.3 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EOO02352.1 - 2.3e-26 91.3 1.1 6e-26 89.9 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain Aldose_epim PF01263.15 EOO02353.1 - 3.1e-44 151.2 0.1 4e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ADH_zinc_N_2 PF13602.1 EOO02354.1 - 4.1e-07 30.9 0.0 8.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO02354.1 - 4.3e-06 26.3 0.1 3.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acp26Ab PF05777.7 EOO02354.1 - 0.15 12.5 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) FAD_binding_2 PF00890.19 EOO02355.1 - 2.3e-55 188.1 1.0 2.7e-55 187.9 0.7 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO02355.1 - 4.2e-09 35.7 0.6 1.8e-07 30.4 0.4 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO02355.1 - 1.5e-08 34.4 1.2 4.6e-08 32.9 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EOO02355.1 - 3.9e-07 29.4 0.3 9.6e-07 28.2 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EOO02355.1 - 6.2e-07 28.6 6.3 7.6e-05 21.7 1.7 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EOO02355.1 - 3.7e-05 23.8 0.1 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO02355.1 - 0.00012 22.0 0.4 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO02355.1 - 0.00016 20.2 8.4 0.00031 19.3 0.6 2.9 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EOO02355.1 - 0.00026 20.1 0.9 0.00078 18.6 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EOO02355.1 - 0.00055 19.1 0.7 0.00084 18.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EOO02355.1 - 0.0011 19.2 0.6 0.0072 16.7 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO02355.1 - 0.019 13.8 0.8 0.029 13.3 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EOO02355.1 - 0.081 12.4 0.2 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S5 PF00333.15 EOO02356.1 - 4.3e-26 90.4 1.5 1.2e-25 88.9 1.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EOO02356.1 - 1.1e-20 72.6 0.0 2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain AhpC-TSA PF00578.16 EOO02357.1 - 1.7e-31 108.4 0.0 2.2e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EOO02357.1 - 2.4e-11 43.0 0.1 4.8e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EOO02357.1 - 1.3e-10 41.0 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin GET2 PF08690.5 EOO02358.1 - 1.9 7.6 5.8 2.7 7.1 4.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Rrn6 PF10214.4 EOO02358.1 - 8.3 4.3 10.0 0.7 7.9 2.5 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor F-box-like PF12937.2 EOO02359.1 - 5.3e-05 22.8 0.0 0.00079 19.1 0.0 2.9 3 1 0 3 3 3 1 F-box-like DUF4267 PF14087.1 EOO02360.1 - 6.1e-13 48.3 1.0 7e-13 48.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) FHA PF00498.21 EOO02361.1 - 6.6e-10 38.9 0.1 1.4e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EOO02361.1 - 0.00017 21.6 0.1 0.0026 17.8 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4554 PF15091.1 EOO02361.1 - 0.086 11.5 0.4 0.19 10.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Acetyltransf_1 PF00583.19 EOO02362.1 - 1.3e-10 41.1 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EOO02362.1 - 2.4e-06 27.6 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EOO02362.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EOO02362.1 - 0.00074 19.6 0.0 0.00094 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO02362.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain ADK_lid PF05191.9 EOO02362.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase, active site lid Acetyltransf_4 PF13420.1 EOO02362.1 - 0.1 12.5 0.0 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EOO02362.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EOO02362.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Memo PF01875.12 EOO02363.1 - 3.1e-72 242.7 0.0 3.6e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein IMS PF00817.15 EOO02364.1 - 1.7e-42 144.7 0.2 3.2e-42 143.8 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EOO02364.1 - 2e-17 63.3 0.0 4.8e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EOO02364.1 - 1.9e-05 24.3 0.0 4.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 EOO02364.1 - 0.0062 16.1 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 VPS28 protein Arg_repressor PF01316.16 EOO02364.1 - 0.15 11.6 0.7 0.32 10.5 0.5 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Cupin_2 PF07883.6 EOO02365.1 - 2.7e-11 42.7 0.1 3.6e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EOO02365.1 - 3.2e-05 23.4 0.0 3.6e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EOO02365.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Auxin_BP PF02041.11 EOO02365.1 - 0.0058 16.0 0.0 0.0069 15.8 0.0 1.0 1 0 0 1 1 1 1 Auxin binding protein MFS_1 PF07690.11 EOO02366.1 - 7.6e-33 113.6 27.0 7.6e-33 113.6 18.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TMPIT PF07851.8 EOO02366.1 - 0.19 10.7 2.7 0.37 9.7 1.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein TLD PF07534.11 EOO02367.1 - 1.6e-29 102.6 0.0 3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 TLD MUG2_C PF08593.5 EOO02367.1 - 3.9e-14 52.6 0.2 1.2e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal DUF3176 PF11374.3 EOO02368.1 - 0.043 13.6 1.4 0.18 11.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) Peptidase_S8 PF00082.17 EOO02369.1 - 1.9e-44 151.9 17.0 2.9e-44 151.3 11.8 1.2 1 0 0 1 1 1 1 Subtilase family COesterase PF00135.23 EOO02370.1 - 1.5e-43 149.3 0.7 3.1e-24 85.6 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO02370.1 - 0.051 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold NmrA PF05368.8 EOO02371.1 - 1.3e-25 90.0 0.5 1.6e-25 89.6 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO02371.1 - 1.6e-18 67.3 0.4 2.5e-18 66.7 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EOO02371.1 - 5.1e-07 29.3 0.1 1.3e-06 28.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EOO02371.1 - 1e-06 27.9 0.9 1.8e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EOO02371.1 - 0.00056 18.7 0.1 0.0013 17.4 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EOO02371.1 - 0.00061 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EOO02371.1 - 0.0018 18.2 0.1 0.0036 17.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EOO02371.1 - 0.0042 17.3 0.1 0.0082 16.3 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EOO02371.1 - 0.012 15.9 0.5 0.031 14.5 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.10 EOO02371.1 - 0.018 14.6 0.3 0.056 13.0 0.1 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 EOO02371.1 - 0.018 14.9 0.3 0.041 13.7 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase XdhC_C PF13478.1 EOO02371.1 - 0.094 13.0 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain DUF2095 PF09868.4 EOO02371.1 - 0.12 12.1 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) HgmA PF04209.8 EOO02373.1 - 8.3e-97 324.2 0.0 9.5e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase UbiA PF01040.13 EOO02374.1 - 1.1e-23 83.7 17.4 1.3e-23 83.5 12.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 EOO02374.1 - 0.14 12.2 0.2 0.39 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pyr_redox PF00070.22 EOO02375.1 - 1.1e-15 57.8 1.3 1.4e-13 51.0 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO02375.1 - 2.6e-13 50.3 0.5 6.6e-07 29.4 0.1 2.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO02375.1 - 4.3e-07 30.1 0.6 0.00026 21.1 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO02375.1 - 6.3e-06 25.3 2.0 0.016 14.1 0.2 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EOO02375.1 - 0.00011 21.2 0.1 0.00023 20.1 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EOO02375.1 - 0.0013 17.3 0.5 0.68 8.3 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 EOO02375.1 - 0.0016 17.1 0.4 0.99 7.9 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EOO02375.1 - 0.0036 16.2 0.2 0.0074 15.2 0.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein DNA_processg_A PF02481.10 EOO02375.1 - 0.0071 15.2 0.1 2.3 7.0 0.1 2.4 2 0 0 2 2 2 2 DNA recombination-mediator protein A GIDA PF01134.17 EOO02375.1 - 0.038 12.8 0.6 0.84 8.4 0.1 2.7 2 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EOO02375.1 - 0.04 13.6 4.9 4.5 7.0 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EOO02375.1 - 0.082 11.9 1.9 0.084 11.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.10 EOO02375.1 - 0.089 10.9 0.4 0.31 9.1 0.1 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) AMP-binding PF00501.23 EOO02376.1 - 2.3e-28 98.7 0.1 3.2e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO02376.1 - 7e-13 49.3 0.0 1.2e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 EOO02377.1 - 8.6e-43 145.8 0.5 1.3e-42 145.2 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EOO02377.1 - 0.0027 17.8 0.1 0.005 17.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.10 EOO02378.1 - 8.1e-90 301.4 34.9 9.6e-90 301.2 24.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC_tran PF00005.22 EOO02379.1 - 5.1e-31 107.7 0.0 8.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EOO02379.1 - 1.3e-10 41.2 3.5 1.7e-10 40.7 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EOO02379.1 - 2.6e-09 37.4 0.0 3.1e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EOO02379.1 - 5e-05 22.6 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EOO02379.1 - 0.00015 21.2 0.1 0.0004 19.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EOO02379.1 - 0.00025 21.1 0.1 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EOO02379.1 - 0.00033 20.5 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EOO02379.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EOO02379.1 - 0.0076 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EOO02379.1 - 0.009 16.1 0.1 0.097 12.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EOO02379.1 - 0.012 15.5 0.1 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EOO02379.1 - 0.019 14.3 0.4 0.092 12.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EOO02379.1 - 0.02 15.7 0.6 0.042 14.6 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EOO02379.1 - 0.039 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EOO02379.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 EOO02379.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 EOO02379.1 - 0.058 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EOO02379.1 - 0.081 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EOO02379.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EOO02379.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EOO02379.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin family TrkH PF02386.11 EOO02380.1 - 7.7e-48 162.8 7.8 1.4e-42 145.5 0.9 2.1 2 0 0 2 2 2 2 Cation transport protein DUF3336 PF11815.3 EOO02381.1 - 1.8e-35 121.5 0.0 3.5e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EOO02381.1 - 1.5e-23 83.7 0.0 3.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF463 PF04317.7 EOO02382.1 - 0.054 12.0 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Translin PF01997.11 EOO02383.1 - 4.9e-43 147.0 0.0 6e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Translin family SQS_PSY PF00494.14 EOO02384.1 - 4.2e-37 127.8 0.0 1.4e-36 126.2 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase RPEL PF02755.10 EOO02385.1 - 2.6e-18 64.7 4.2 1.2e-09 37.2 0.0 2.8 3 0 0 3 3 3 2 RPEL repeat Myb_DNA-bind_2 PF08914.6 EOO02386.1 - 0.13 12.0 0.7 0.31 10.8 0.5 1.5 1 0 0 1 1 1 0 Rap1 Myb domain HIG_1_N PF04588.8 EOO02387.1 - 8.8e-24 83.0 1.6 1.3e-23 82.5 1.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF445 PF04286.7 EOO02387.1 - 0.077 12.5 1.6 0.092 12.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1510 PF07423.6 EOO02387.1 - 0.078 12.3 9.2 0.11 11.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cyt-b5 PF00173.23 EOO02388.1 - 4.1e-15 55.3 0.0 5.7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RmlD_sub_bind PF04321.12 EOO02389.1 - 4.1e-13 48.8 0.0 1e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EOO02389.1 - 4.2e-10 39.4 0.0 7.8e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EOO02389.1 - 0.00049 19.0 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EOO02389.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Macro PF01661.16 EOO02389.1 - 0.034 14.0 0.2 0.23 11.4 0.0 2.3 3 1 0 3 3 3 0 Macro domain KR PF08659.5 EOO02389.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.6 2 0 0 2 2 2 0 KR domain Rhodanese PF00581.15 EOO02390.1 - 7.2e-21 74.6 0.0 7.8e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RAP1 PF07218.6 EOO02391.1 - 1.1 7.2 14.5 1.7 6.6 10.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) U79_P34 PF03064.11 EOO02391.1 - 1.7 8.1 27.5 4 6.8 19.1 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Paf1 PF03985.8 EOO02391.1 - 2.1 7.0 29.5 3.2 6.4 20.4 1.2 1 0 0 1 1 1 0 Paf1 DDHD PF02862.12 EOO02391.1 - 3.3 7.4 20.2 6.7 6.4 14.0 1.5 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 EOO02391.1 - 4.2 4.9 20.4 6.3 4.3 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 EOO02391.1 - 4.2 7.0 21.2 7.9 6.1 14.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Borrelia_P83 PF05262.6 EOO02391.1 - 4.9 5.3 29.7 10 4.2 20.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.10 EOO02391.1 - 5.4 5.5 19.6 8.7 4.8 13.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpb1_5 PF04998.12 EOO02391.1 - 6.7 5.8 16.4 32 3.6 11.8 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DUF1510 PF07423.6 EOO02391.1 - 8.3 5.7 38.7 17 4.6 26.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDRGK PF09756.4 EOO02391.1 - 9.5 5.5 45.1 65 2.8 0.0 2.5 2 0 0 2 2 2 0 DDRGK domain Grp1_Fun34_YaaH PF01184.14 EOO02392.1 - 5.6e-87 290.4 19.5 7.8e-87 289.9 13.5 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family mRNA_triPase PF02940.10 EOO02393.1 - 3.6e-35 121.6 0.5 4.1e-35 121.4 0.4 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain FAD_binding_3 PF01494.14 EOO02394.1 - 0.0006 18.9 0.1 0.0016 17.5 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Tannase PF07519.6 EOO02395.1 - 1.5e-51 175.6 0.4 2.2e-50 171.7 0.3 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase PAH PF02671.16 EOO02395.1 - 0.0086 15.6 0.0 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Paired amphipathic helix repeat SNARE PF05739.14 EOO02396.1 - 9.5e-12 44.4 7.6 9.5e-12 44.4 5.3 3.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EOO02396.1 - 1.3e-05 25.2 16.5 0.004 17.3 11.4 3.1 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.1 EOO02396.1 - 0.0017 18.3 5.0 0.0017 18.3 3.5 2.4 2 0 0 2 2 2 1 Syntaxin-like protein EphA2_TM PF14575.1 EOO02396.1 - 0.0029 17.9 0.5 0.0073 16.6 0.3 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EOO02396.1 - 0.003 17.5 1.3 0.0089 16.0 0.9 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 EOO02396.1 - 0.0061 15.9 1.8 0.013 14.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Rifin_STEVOR PF02009.11 EOO02396.1 - 0.0063 16.1 6.4 0.0063 16.1 4.4 2.0 1 1 0 2 2 2 1 Rifin/stevor family Endomucin PF07010.7 EOO02396.1 - 0.017 14.5 0.2 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Endomucin DUF2096 PF09869.4 EOO02396.1 - 0.024 14.5 0.7 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Lge1 PF11488.3 EOO02396.1 - 0.029 14.5 2.9 2 8.6 0.0 3.0 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF3792 PF12670.2 EOO02396.1 - 0.062 13.1 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Wzy_C PF04932.10 EOO02396.1 - 0.14 11.9 0.7 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 O-Antigen ligase DUF2839 PF10999.3 EOO02396.1 - 0.15 12.1 0.6 0.33 11.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) 7tm_7 PF08395.7 EOO02396.1 - 0.16 10.9 4.5 0.25 10.3 0.0 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor Chordopox_A13L PF05961.6 EOO02396.1 - 0.28 11.1 2.6 0.67 9.9 1.8 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2116 PF09889.4 EOO02396.1 - 0.3 10.9 2.0 0.91 9.3 1.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MitMem_reg PF13012.1 EOO02396.1 - 0.68 10.0 5.0 0.45 10.6 0.5 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function V-SNARE PF05008.10 EOO02396.1 - 0.69 10.1 15.4 2.6 8.2 2.3 3.8 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF4094 PF13334.1 EOO02396.1 - 0.79 10.1 5.5 1.1 9.7 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Sec5 PF15469.1 EOO02396.1 - 1.1 8.9 7.9 3 7.5 1.7 2.8 2 1 1 3 3 3 0 Exocyst complex component Sec5 DUF1993 PF09351.5 EOO02396.1 - 3.7 7.4 8.9 0.48 10.3 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DUF4381 PF14316.1 EOO02396.1 - 3.8 7.6 7.1 39 4.3 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Shisa PF13908.1 EOO02396.1 - 7.3 6.7 7.2 0.35 11.0 0.2 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2203 PF09969.4 EOO02396.1 - 10 6.4 10.1 35 4.6 1.8 3.1 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Oxidored_molyb PF00174.14 EOO02397.1 - 2.5e-53 179.9 0.0 3.7e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EOO02397.1 - 3.1e-28 98.0 0.2 8.1e-28 96.6 0.1 1.7 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EOO02397.1 - 4.9e-14 51.8 0.2 8.5e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 EOO02397.1 - 0.46 10.4 2.2 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Jiv90 PF14901.1 EOO02397.1 - 2.2 8.3 7.4 4.5 7.3 0.0 4.2 4 1 1 5 5 5 0 Cleavage inducing molecular chaperone Abhydrolase_6 PF12697.2 EOO02398.1 - 6.4e-11 42.5 1.8 6.4e-11 42.5 1.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02398.1 - 0.0002 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO02398.1 - 0.00061 19.4 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EOO02398.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.7 EOO02398.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 EOO02399.1 - 6.9e-19 68.6 7.2 9.3e-19 68.2 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02399.1 - 3.4e-08 33.3 1.7 1.2e-07 31.6 1.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EOO02399.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 EOO02399.1 - 0.036 13.6 0.1 0.3 10.6 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EOO02399.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1057 PF06342.7 EOO02399.1 - 0.06 12.1 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Transaldolase PF00923.14 EOO02401.1 - 2e-34 119.0 0.0 3.7e-34 118.1 0.0 1.3 1 1 0 1 1 1 1 Transaldolase SSF PF00474.12 EOO02402.1 - 2.7e-21 75.6 28.3 4.9e-21 74.8 19.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family GFO_IDH_MocA PF01408.17 EOO02403.1 - 2.8e-17 63.3 0.0 6.1e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EOO02403.1 - 2.1e-08 33.9 0.0 1.4e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 EOO02403.1 - 0.03 14.1 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 EOO02404.1 - 1.7e-12 46.7 29.4 5.9e-08 31.8 0.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 EOO02405.1 - 8e-13 48.2 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.17 EOO02406.1 - 1.3e-33 116.2 0.7 1.9e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SKI PF01202.17 EOO02407.1 - 3.1e-14 53.1 0.0 3.8e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EOO02407.1 - 4e-12 46.2 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EOO02407.1 - 2.3e-11 44.5 0.0 5.1e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EOO02407.1 - 4.5e-10 39.9 0.0 7.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EOO02407.1 - 2.8e-05 24.2 0.1 7.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02407.1 - 0.00024 20.7 0.5 0.00053 19.6 0.2 1.8 2 1 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 EOO02407.1 - 0.00056 19.9 0.4 0.0012 18.8 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 EOO02407.1 - 0.001 17.8 0.0 0.0019 16.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EOO02407.1 - 0.0011 18.6 0.1 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EOO02407.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.7 2 0 0 2 2 1 1 NACHT domain APS_kinase PF01583.15 EOO02407.1 - 0.002 17.7 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase T2SE PF00437.15 EOO02407.1 - 0.0026 16.7 0.2 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EOO02407.1 - 0.0031 16.5 0.0 0.0031 16.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EOO02407.1 - 0.0035 17.5 0.3 0.0067 16.6 0.2 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EOO02407.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EOO02407.1 - 0.0079 15.3 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EOO02407.1 - 0.012 15.4 0.1 0.11 12.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain ADK PF00406.17 EOO02407.1 - 0.033 14.0 0.3 5 6.9 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase ABC_tran PF00005.22 EOO02407.1 - 0.033 14.4 0.0 0.051 13.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EOO02407.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EOO02407.1 - 0.036 13.4 0.2 0.053 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EOO02407.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EOO02407.1 - 0.042 13.8 0.4 0.062 13.2 0.3 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EOO02407.1 - 0.047 13.7 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 EOO02407.1 - 0.049 12.8 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin2 PF13189.1 EOO02407.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_31 PF13614.1 EOO02407.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IPPT PF01715.12 EOO02407.1 - 0.066 12.2 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 IPP transferase CoaE PF01121.15 EOO02407.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase IPT PF01745.11 EOO02407.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase NTPase_1 PF03266.10 EOO02407.1 - 0.12 12.0 0.6 0.68 9.6 0.1 2.0 1 1 0 2 2 2 0 NTPase CbiA PF01656.18 EOO02407.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EOO02407.1 - 0.29 11.4 1.2 0.33 11.2 0.2 1.5 2 0 0 2 2 1 0 AAA domain FAD_binding_3 PF01494.14 EOO02408.1 - 9.6e-13 47.9 0.1 2.6e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EOO02408.1 - 1.2e-05 24.4 0.0 0.005 15.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO02408.1 - 9.2e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EOO02408.1 - 0.00015 22.1 0.2 0.21 12.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO02408.1 - 0.0035 16.3 0.1 0.0084 15.0 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EOO02408.1 - 0.0088 14.9 0.3 0.11 11.2 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.12 EOO02408.1 - 0.023 13.7 0.3 0.047 12.7 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EOO02408.1 - 0.049 13.5 0.1 0.089 12.6 0.1 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EOO02408.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EOO02408.1 - 0.089 12.5 1.7 5 6.8 0.3 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EOO02408.1 - 0.15 10.8 0.0 5.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.13 EOO02409.1 - 2.2e-22 79.1 0.3 4.8e-22 78.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO02409.1 - 1.6e-05 24.7 15.0 2.8e-05 23.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EOO02410.1 - 1.3e-23 82.7 3.3 2.2e-23 82.0 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO02410.1 - 6.9e-17 61.2 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EOO02410.1 - 3.2e-09 36.9 0.2 5.8e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EOO02410.1 - 0.01 14.9 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC2_membrane PF01061.19 EOO02411.1 - 3.4e-77 258.3 46.4 5.5e-41 140.0 12.1 3.5 2 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EOO02411.1 - 9.4e-44 149.0 0.0 2e-23 83.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EOO02411.1 - 3.4e-26 90.8 0.6 4.6e-24 84.0 0.1 2.7 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EOO02411.1 - 1.2e-12 47.5 21.8 1.9e-07 30.4 5.0 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EOO02411.1 - 3.2e-06 27.2 0.3 0.0014 18.6 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EOO02411.1 - 6.5e-06 26.3 0.0 0.049 13.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EOO02411.1 - 3.5e-05 23.2 0.1 0.0068 15.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EOO02411.1 - 6.7e-05 22.1 0.5 0.0005 19.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EOO02411.1 - 0.00016 20.9 0.0 0.27 10.4 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EOO02411.1 - 0.00026 20.6 0.4 0.027 14.0 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EOO02411.1 - 0.00029 20.5 0.0 0.48 10.2 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 EOO02411.1 - 0.0008 19.6 0.3 6.1 7.0 0.0 4.0 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EOO02411.1 - 0.0023 17.4 0.5 0.022 14.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EOO02411.1 - 0.0031 17.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EOO02411.1 - 0.0045 16.6 0.2 0.41 10.2 0.1 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EOO02411.1 - 0.0046 16.4 0.2 0.28 10.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EOO02411.1 - 0.0098 15.8 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EOO02411.1 - 0.011 15.2 0.0 0.5 9.8 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EOO02411.1 - 0.012 15.6 0.1 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EOO02411.1 - 0.013 16.2 0.0 0.27 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EOO02411.1 - 0.032 13.7 0.2 0.59 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EOO02411.1 - 0.038 14.4 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EOO02411.1 - 0.042 13.7 0.1 0.39 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EOO02411.1 - 0.051 13.8 0.1 2 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EOO02411.1 - 0.057 13.3 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EOO02411.1 - 0.063 13.2 0.1 7 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EOO02411.1 - 0.18 10.6 0.3 2.7 6.7 0.1 2.3 2 1 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 EOO02411.1 - 0.19 10.4 0.1 0.56 8.9 0.0 1.7 2 0 0 2 2 2 0 ArgK protein FKS1_dom1 PF14288.1 EOO02412.1 - 3.6e-38 130.0 2.7 3.8e-38 129.9 0.8 1.9 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF843 PF05814.6 EOO02412.1 - 0.33 10.7 2.6 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Cupin_2 PF07883.6 EOO02413.1 - 4.9e-16 57.9 0.1 1.2e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EOO02413.1 - 0.00034 20.3 2.6 0.0062 16.2 0.5 2.8 2 1 1 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EOO02413.1 - 0.00042 19.7 0.0 1.7 8.0 0.0 2.9 2 1 1 3 3 3 3 Cupin cNMP_binding PF00027.24 EOO02413.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF1992 PF09350.5 EOO02413.1 - 0.036 13.8 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Fungal_trans PF04082.13 EOO02414.1 - 2.6e-16 59.3 0.1 3.9e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO02414.1 - 1.4e-08 34.4 9.4 2.6e-08 33.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 EOO02415.1 - 3.5e-135 451.3 0.1 4e-135 451.2 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FMO-like PF00743.14 EOO02416.1 - 1.1e-21 76.7 0.0 2.2e-16 59.1 0.1 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EOO02416.1 - 1.6e-20 74.0 0.0 3.4e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EOO02416.1 - 2.9e-09 36.3 0.0 2.1e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EOO02416.1 - 1.3e-08 35.0 0.0 2.1e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO02416.1 - 1.8e-05 25.0 0.6 1.9 8.9 0.0 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EOO02416.1 - 0.00018 20.6 0.0 0.029 13.5 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EOO02416.1 - 0.00019 20.6 0.0 0.13 11.3 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO02416.1 - 0.00037 20.4 0.9 0.057 13.4 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EOO02416.1 - 0.00042 19.4 0.2 0.72 8.8 0.2 3.2 4 0 0 4 4 4 2 FAD binding domain DAO PF01266.19 EOO02416.1 - 0.00044 19.2 0.3 0.79 8.5 0.3 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EOO02416.1 - 0.0017 18.1 4.2 0.034 13.9 0.1 3.3 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 EOO02416.1 - 0.002 17.2 0.0 0.38 9.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EOO02416.1 - 0.0043 15.5 0.1 0.39 9.1 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EOO02416.1 - 0.0067 15.3 0.8 0.35 9.6 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EOO02416.1 - 0.061 12.1 0.3 1.5 7.5 0.9 2.5 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 EOO02416.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NmrA PF05368.8 EOO02418.1 - 5e-32 111.0 0.0 1.6e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO02418.1 - 3.2e-13 50.0 0.0 4.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO02418.1 - 2.2e-06 27.2 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EOO02418.1 - 0.00095 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EOO02418.1 - 0.0013 17.4 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EOO02418.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Ribosomal_S11 PF00411.14 EOO02420.1 - 3.5e-10 40.0 0.0 5.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Mito_carr PF00153.22 EOO02421.1 - 8.9e-61 201.6 0.0 2.8e-20 71.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FKBP_C PF00254.23 EOO02422.1 - 1.4e-31 108.3 0.0 5.8e-31 106.3 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF572 PF04502.8 EOO02422.1 - 0.76 8.9 29.9 0.68 9.1 7.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) MFS_1 PF07690.11 EOO02423.1 - 7.4e-53 179.4 35.7 7.4e-53 179.4 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO02423.1 - 2.9e-10 39.3 29.0 1.5e-09 36.9 20.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EOO02423.1 - 5.1e-08 31.5 0.5 7.8e-08 30.9 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2583 PF10762.4 EOO02423.1 - 0.87 9.7 3.7 0.34 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Cpn60_TCP1 PF00118.19 EOO02424.1 - 3e-140 468.0 13.6 3.7e-140 467.7 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EOO02424.1 - 0.024 14.0 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF2263 PF10021.4 EOO02425.1 - 6.2e-26 91.1 0.0 1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Glyco_trans_2_3 PF13632.1 EOO02426.1 - 5e-13 49.2 0.0 9.6e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 ATG11 PF10377.4 EOO02427.1 - 5.1e-42 142.8 0.0 9.2e-42 141.9 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 11 Cleaved_Adhesin PF07675.6 EOO02427.1 - 0.0054 16.3 0.1 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Cleaved Adhesin Domain WD40 PF00400.27 EOO02428.1 - 2.1e-45 151.0 19.7 1.1e-11 44.1 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EOO02428.1 - 7.7e-05 21.0 2.3 0.004 15.3 0.3 3.3 3 1 0 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EOO02428.1 - 0.00079 19.1 0.0 0.011 15.4 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EOO02428.1 - 0.0035 15.7 0.0 0.0076 14.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EOO02428.1 - 0.028 13.9 0.0 14 5.2 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.5 EOO02428.1 - 0.082 11.1 0.1 6.2 4.9 0.0 2.8 3 0 0 3 3 3 0 VID27 cytoplasmic protein zf-UBR PF02207.15 EOO02429.1 - 1.1e-17 63.4 16.1 2.8e-17 62.1 11.2 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EOO02429.1 - 0.00028 20.5 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Arf PF00025.16 EOO02430.1 - 8.1e-30 103.3 0.0 9e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EOO02430.1 - 3.8e-13 49.1 0.0 4.1e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EOO02430.1 - 4.7e-06 25.5 0.0 1.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EOO02430.1 - 3.2e-05 24.3 0.0 7.4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EOO02430.1 - 0.00022 20.4 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EOO02430.1 - 0.0013 18.2 0.0 0.0014 18.1 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain F_bP_aldolase PF01116.15 EOO02431.1 - 1.5e-98 329.4 0.0 1.7e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II FAD_binding_3 PF01494.14 EOO02432.1 - 4.9e-14 52.1 0.1 4.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EOO02432.1 - 0.21 10.3 0.0 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Ribosomal_L9_N PF01281.14 EOO02434.1 - 1.1e-06 27.8 0.0 1.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EOO02434.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DSPc PF00782.15 EOO02435.1 - 2e-16 59.7 0.0 3.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EOO02435.1 - 1.2e-06 28.0 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.1 EOO02435.1 - 3.1e-06 27.2 0.0 0.00044 20.2 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PP1_bind PF15276.1 EOO02435.1 - 0.072 13.1 1.2 0.26 11.3 0.3 2.4 1 1 1 2 2 2 0 Protein phosphatase 1 binding PTPlike_phytase PF14566.1 EOO02435.1 - 0.1 12.6 0.0 0.1 12.6 0.0 2.1 2 1 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EOO02435.1 - 0.14 12.4 1.5 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Mago-bind PF09282.5 EOO02436.1 - 1.4e-13 50.1 2.0 2.5e-13 49.3 1.4 1.4 1 0 0 1 1 1 1 Mago binding Hid1 PF12722.2 EOO02436.1 - 0.45 8.1 1.6 0.45 8.1 1.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ammonium_transp PF00909.16 EOO02437.1 - 1.7e-116 389.0 31.4 1.9e-116 388.8 21.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF373 PF04123.8 EOO02437.1 - 0.88 8.5 5.0 0.12 11.4 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF2207 PF09972.4 EOO02437.1 - 1.4 7.4 7.7 3.9 5.9 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CBFD_NFYB_HMF PF00808.18 EOO02438.1 - 2.6e-09 37.0 0.2 4.8e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EOO02438.1 - 4.9e-05 23.3 0.0 8.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 EOO02438.1 - 0.092 12.5 0.2 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Astro_capsid PF03115.9 EOO02438.1 - 0.21 9.7 8.5 0.3 9.3 5.9 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor GN3L_Grn1 PF08701.6 EOO02439.1 - 8.5e-25 86.4 16.6 1.6e-24 85.6 11.5 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EOO02439.1 - 4.6e-21 74.9 0.1 8.5e-15 54.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EOO02439.1 - 2.9e-07 30.4 4.4 0.013 15.3 0.2 3.7 2 2 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EOO02439.1 - 5e-07 29.3 0.0 0.026 13.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EOO02439.1 - 0.00031 19.9 0.1 0.00053 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EOO02439.1 - 0.00071 18.8 0.0 0.019 14.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EOO02439.1 - 0.013 15.9 1.3 2 8.9 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 EOO02439.1 - 0.019 14.9 1.2 0.19 11.6 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EOO02439.1 - 0.024 13.3 0.1 0.024 13.3 0.1 2.1 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 EOO02439.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B BCS1_N PF08740.6 EOO02440.1 - 2e-39 135.1 0.0 3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EOO02440.1 - 4.8e-19 68.8 0.0 7.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO02440.1 - 1.9e-05 25.4 0.1 6.1e-05 23.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EOO02440.1 - 7.1e-05 22.2 0.0 0.00048 19.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO02440.1 - 0.00015 21.8 0.0 0.00085 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EOO02440.1 - 0.00071 19.4 0.0 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EOO02440.1 - 0.00071 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EOO02440.1 - 0.00083 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EOO02440.1 - 0.00091 18.3 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EOO02440.1 - 0.006 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EOO02440.1 - 0.0076 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EOO02440.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 EOO02440.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EOO02440.1 - 0.015 14.8 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EOO02440.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EOO02440.1 - 0.016 15.5 0.0 0.038 14.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EOO02440.1 - 0.018 14.7 0.4 0.084 12.6 0.0 2.4 2 1 0 2 2 1 0 Part of AAA domain KaiC PF06745.8 EOO02440.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 EOO02440.1 - 0.03 13.8 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EOO02440.1 - 0.041 14.3 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 EOO02440.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EOO02440.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EOO02440.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 EOO02440.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain FMN_bind PF04205.9 EOO02440.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 FMN-binding domain DUF258 PF03193.11 EOO02440.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EOO02440.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EOO02440.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EOO02440.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_15 PF00723.16 EOO02441.1 - 1.4e-65 221.6 0.0 5.6e-44 150.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EOO02441.1 - 9.3e-34 114.9 1.4 2.2e-33 113.7 1.0 1.7 1 0 0 1 1 1 1 Starch binding domain Peptidase_S66 PF02016.10 EOO02442.1 - 9.8e-55 185.4 0.0 1.1e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 LD-carboxypeptidase TauD PF02668.11 EOO02443.1 - 2e-09 37.5 0.1 6e-07 29.3 0.1 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EOO02443.1 - 0.084 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 CsiD IATP PF04568.7 EOO02444.1 - 8.1e-21 73.9 0.7 9.5e-21 73.7 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HrpB2 PF09487.5 EOO02444.1 - 0.042 14.0 0.2 0.056 13.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) DUF489 PF04356.7 EOO02444.1 - 0.06 12.9 0.3 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Baculo_PP31 PF05311.6 EOO02444.1 - 0.11 11.7 0.8 0.12 11.5 0.6 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NPV_P10 PF05531.7 EOO02444.1 - 0.14 12.3 1.1 0.21 11.8 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1003 PF06210.6 EOO02444.1 - 0.35 10.8 2.9 0.5 10.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) TspO_MBR PF03073.10 EOO02445.1 - 1.2e-40 138.4 5.0 1.5e-40 138.1 3.5 1.1 1 0 0 1 1 1 1 TspO/MBR family HAD_2 PF13419.1 EOO02446.1 - 3.7e-16 59.8 0.0 4.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EOO02446.1 - 5.1e-10 38.9 0.0 8.9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EOO02446.1 - 1.5e-08 35.3 0.0 0.00014 22.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EOO02446.1 - 2.4e-05 24.6 0.0 2.8e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EOO02446.1 - 0.0075 16.1 0.1 0.11 12.3 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 EOO02446.1 - 0.02 14.9 0.0 0.048 13.6 0.0 1.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 COesterase PF00135.23 EOO02447.1 - 5.2e-74 249.8 0.0 3.9e-61 207.3 0.2 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 EOO02447.1 - 4.1e-05 23.2 0.1 0.00033 20.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_Rpb2_6 PF00562.23 EOO02448.1 - 6.9e-115 383.8 0.1 8.8e-115 383.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 EOO02448.1 - 8.8e-28 97.0 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EOO02448.1 - 2.2e-25 88.1 0.0 4.8e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EOO02448.1 - 1.8e-23 82.2 0.0 3.6e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EOO02448.1 - 1.5e-14 53.9 0.0 7.3e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EOO02448.1 - 0.0019 18.0 0.2 0.0047 16.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Fringe PF02434.11 EOO02449.1 - 2.7e-06 26.8 0.1 4e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 EOO02449.1 - 2e-05 24.2 0.1 3.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EOO02449.1 - 0.031 13.9 1.4 0.058 13.1 1.0 1.3 1 0 0 1 1 1 0 PAN domain DUF4066 PF13278.1 EOO02450.1 - 1.3e-12 47.2 0.0 1.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EOO02450.1 - 0.0045 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PGM_PMM_I PF02878.11 EOO02451.1 - 8.3e-33 112.7 0.0 1.3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EOO02451.1 - 2.2e-25 88.9 0.0 3.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EOO02451.1 - 4.7e-15 55.7 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EOO02451.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3661 PF12400.3 EOO02452.1 - 4.2e-43 146.5 1.5 6.4e-43 145.9 1.0 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein Zip PF02535.17 EOO02452.1 - 0.33 9.9 1.8 0.51 9.2 0.8 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter His_Phos_2 PF00328.17 EOO02453.1 - 6.7e-43 147.3 0.0 7.6e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HET PF06985.6 EOO02454.1 - 4.2e-22 78.8 0.1 7.7e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.15 EOO02455.1 - 2.7e-58 196.7 1.1 4.7e-58 195.9 0.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EOO02455.1 - 1.4e-25 89.9 1.4 1.4e-25 89.9 1.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EOO02455.1 - 1.2e-23 84.6 0.0 5.7e-23 82.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO02455.1 - 1.3e-18 66.7 0.0 2.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EOO02455.1 - 2.2e-14 54.0 0.0 6.3e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO02455.1 - 4e-05 23.3 0.4 0.0022 17.5 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_9_N PF15420.1 EOO02455.1 - 4.3 7.0 9.1 0.95 9.1 1.7 2.6 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus RabGAP-TBC PF00566.13 EOO02456.1 - 4.3e-30 104.7 0.0 3.1e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HTH_30 PF13556.1 EOO02456.1 - 0.047 13.2 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-CSL PF05207.8 EOO02457.1 - 4.4e-18 64.5 0.3 6.5e-18 63.9 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EOO02457.1 - 6.9e-12 44.9 0.3 1.8e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Ribosomal_L35p PF01632.14 EOO02457.1 - 0.24 11.3 5.1 0.1 12.5 1.3 2.0 1 1 1 2 2 2 0 Ribosomal protein L35 Tim44 PF04280.10 EOO02458.1 - 2.4e-33 115.1 0.0 6.7e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain PPV_E1_C PF00519.12 EOO02458.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase HMG_box PF00505.14 EOO02459.1 - 1.6e-25 89.1 1.4 2.1e-25 88.7 0.9 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EOO02459.1 - 8.6e-19 67.6 1.8 1.2e-18 67.1 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EOO02459.1 - 0.00052 19.7 0.5 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EOO02459.1 - 0.025 14.7 0.1 0.068 13.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 EOO02459.1 - 0.086 13.1 1.5 0.35 11.1 1.0 2.0 1 1 0 1 1 1 0 Cold shock protein DEAD box A NmrA PF05368.8 EOO02461.1 - 2.6e-12 46.4 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO02461.1 - 6.5e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EOO02461.1 - 1.1e-06 28.7 0.2 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02461.1 - 2.7e-05 23.8 0.3 5.2e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO02461.1 - 2.9e-05 23.6 0.1 4.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO02461.1 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EOO02461.1 - 0.0034 17.7 3.0 0.028 14.8 0.9 2.8 2 1 1 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EOO02461.1 - 0.04 12.8 0.1 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EOO02461.1 - 0.12 11.2 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain bact-PGI_C PF10432.4 EOO02462.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region Rhodanese PF00581.15 EOO02462.1 - 0.092 13.0 0.0 0.51 10.6 0.0 2.1 1 1 1 2 2 2 0 Rhodanese-like domain SIS PF01380.17 EOO02462.1 - 0.12 11.9 0.3 0.49 9.9 0.0 2.2 3 0 0 3 3 3 0 SIS domain AAA PF00004.24 EOO02463.1 - 9.9e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO02463.1 - 3.6e-06 27.1 0.1 0.00059 19.9 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EOO02463.1 - 2.2e-05 24.2 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EOO02463.1 - 0.00022 21.1 0.0 0.00071 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EOO02463.1 - 0.00026 21.0 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EOO02463.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EOO02463.1 - 0.0044 17.8 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02463.1 - 0.0078 15.9 0.2 0.021 14.5 0.1 1.7 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EOO02463.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EOO02463.1 - 0.018 14.9 0.1 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EOO02463.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EOO02463.1 - 0.028 14.0 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EOO02463.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EOO02463.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EOO02463.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EOO02463.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EOO02463.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EOO02463.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EOO02463.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EOO02463.1 - 0.14 11.8 0.9 11 5.6 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 EOO02463.1 - 0.15 11.4 0.2 0.42 9.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 EOO02464.1 - 3.5e-20 72.9 0.2 5e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_5 PF13857.1 EOO02465.1 - 4.4e-12 45.8 0.0 6.4e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO02465.1 - 1.8e-06 28.3 0.0 0.00021 21.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EOO02465.1 - 0.00038 20.1 0.1 0.023 14.4 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeat PX PF00787.19 EOO02465.1 - 0.00069 19.3 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 PX domain Ank_2 PF12796.2 EOO02465.1 - 0.0012 19.1 0.0 0.0052 17.1 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EOO02465.1 - 0.0027 17.8 0.0 0.79 10.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Phage_Gp23 PF10669.4 EOO02465.1 - 1.1 9.4 4.9 20 5.2 0.7 2.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) AAA_11 PF13086.1 EOO02466.1 - 9.5e-60 202.1 0.5 5e-59 199.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EOO02466.1 - 3.2e-28 98.4 0.0 7.2e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02466.1 - 4.8e-13 48.6 0.2 5e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EOO02466.1 - 1.7e-10 40.7 0.0 8.7e-09 35.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EOO02466.1 - 4e-08 33.2 0.0 1.5e-07 31.3 0.0 2.0 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EOO02466.1 - 6.3e-06 25.7 0.1 2.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EOO02466.1 - 6.5e-06 25.3 0.4 4.3e-05 22.6 0.3 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EOO02466.1 - 0.00012 22.1 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EOO02466.1 - 0.00019 21.0 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EOO02466.1 - 0.00058 19.3 0.2 0.019 14.3 0.0 2.9 1 1 2 3 3 3 1 AAA domain Helicase_RecD PF05127.9 EOO02466.1 - 0.00092 18.8 0.0 0.09 12.3 0.0 2.4 2 0 0 2 2 2 1 Helicase Flavi_DEAD PF07652.9 EOO02466.1 - 0.0013 18.5 0.1 0.0086 15.8 0.0 2.3 3 0 0 3 3 2 1 Flavivirus DEAD domain DEAD PF00270.24 EOO02466.1 - 0.0013 18.2 0.0 0.012 15.1 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EOO02466.1 - 0.0015 17.5 0.2 0.0064 15.4 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Zot PF05707.7 EOO02466.1 - 0.0018 17.8 0.2 0.014 14.8 0.0 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EOO02466.1 - 0.0029 17.0 0.0 0.0077 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EOO02466.1 - 0.0031 17.0 0.0 0.016 14.6 0.0 1.9 1 1 1 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EOO02466.1 - 0.0048 16.8 0.2 0.016 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 EOO02466.1 - 0.0085 14.7 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 EOO02466.1 - 0.0087 15.3 0.0 0.062 12.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EOO02466.1 - 0.01 16.0 0.7 0.072 13.2 0.0 2.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.2 EOO02466.1 - 0.052 12.8 0.1 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_5 PF07728.9 EOO02466.1 - 0.06 13.0 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 EOO02466.1 - 0.12 11.7 1.3 2 7.8 0.9 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 EOO02466.1 - 0.14 11.6 0.9 0.4 10.1 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EOO02466.1 - 0.43 11.4 2.8 0.98 10.2 0.9 2.6 2 1 0 2 2 1 0 AAA domain RNB PF00773.14 EOO02468.1 - 2.6e-92 309.5 0.0 3.9e-92 309.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EOO02468.1 - 1.2e-08 35.1 0.5 7.6e-08 32.5 0.1 2.6 2 1 0 2 2 2 1 PIN domain OB_RNB PF08206.6 EOO02468.1 - 0.058 12.9 0.0 0.2 11.2 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease B OB domain CENP-H PF05837.7 EOO02469.1 - 5.2e-26 90.8 9.0 7.4e-26 90.3 2.7 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) FlxA PF14282.1 EOO02469.1 - 0.25 11.3 5.8 0.25 11.2 1.1 2.3 2 0 0 2 2 2 0 FlxA-like protein Phage_lysis PF03245.8 EOO02469.1 - 0.28 11.1 7.0 0.16 11.9 0.2 2.7 2 2 1 3 3 3 0 Bacteriophage Rz lysis protein AATF-Che1 PF13339.1 EOO02469.1 - 0.33 11.0 5.6 1.7 8.8 0.3 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF972 PF06156.8 EOO02469.1 - 0.67 10.3 10.1 0.16 12.3 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) COG2 PF06148.6 EOO02469.1 - 1.1 9.1 6.0 0.5 10.2 1.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Flagellin_N PF00669.15 EOO02469.1 - 1.4 8.6 4.1 3.8 7.3 0.4 2.4 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region CorA PF01544.13 EOO02469.1 - 8.6 5.2 7.2 1.8 7.5 0.8 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FimP PF09766.4 EOO02470.1 - 5e-28 98.2 12.2 7.6e-28 97.5 8.4 1.2 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 EOO02470.1 - 0.0067 16.2 0.9 0.0067 16.2 0.6 3.5 2 2 2 4 4 4 1 K-box region DUF87 PF01935.12 EOO02470.1 - 0.025 14.4 5.3 0.03 14.1 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Cortex-I_coil PF09304.5 EOO02470.1 - 0.026 14.5 19.5 0.034 14.1 4.2 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 EOO02470.1 - 0.042 13.6 18.4 0.41 10.4 3.4 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flagellin_N PF00669.15 EOO02470.1 - 0.16 11.7 9.1 0.88 9.3 0.5 2.6 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 EOO02470.1 - 0.19 12.0 13.2 0.9 9.9 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EOO02470.1 - 1 9.2 27.3 0.19 11.6 1.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) Snapin_Pallidin PF14712.1 EOO02470.1 - 1.7 8.9 14.8 0.22 11.8 2.6 2.7 2 1 1 3 3 3 0 Snapin/Pallidin ADIP PF11559.3 EOO02470.1 - 2.8 7.8 21.6 4.3 7.2 2.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RRM_1 PF00076.17 EOO02471.1 - 8.2e-19 67.0 0.7 2.4e-18 65.5 0.2 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02471.1 - 1.1e-13 50.9 0.0 1.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02471.1 - 4.2e-09 36.1 0.1 6.6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.17 EOO02472.1 - 2.4e-13 50.6 0.0 6.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EOO02472.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA-rel_N PF06812.7 EOO02472.1 - 0.11 12.3 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 ImpA-related N-terminal DUF1768 PF08719.6 EOO02473.1 - 8.2e-52 175.1 0.0 9.7e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Oxysterol_BP PF01237.13 EOO02474.1 - 3.9e-88 295.3 0.0 4.7e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RNase_T PF00929.19 EOO02475.1 - 1.9e-29 103.0 0.2 2.2e-29 102.8 0.2 1.0 1 0 0 1 1 1 1 Exonuclease DUF3622 PF12286.3 EOO02475.1 - 0.028 14.7 0.1 0.078 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3622) HK97-gp10_like PF04883.7 EOO02475.1 - 0.15 12.9 0.3 9.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component HlyIII PF03006.15 EOO02476.1 - 2.7e-54 183.9 21.4 3.3e-54 183.6 14.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related BAF PF02961.9 EOO02476.1 - 0.13 12.5 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Barrier to autointegration factor DUF883 PF05957.8 EOO02476.1 - 0.14 12.6 7.2 0.97 9.8 1.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YchF-GTPase_C PF06071.8 EOO02477.1 - 3.8e-34 116.3 0.3 8.6e-34 115.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EOO02477.1 - 1.8e-12 47.2 0.0 4.7e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EOO02477.1 - 0.00033 20.4 0.1 0.00084 19.1 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EOO02477.1 - 0.00051 19.3 0.0 0.00093 18.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EOO02477.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EOO02477.1 - 0.046 14.0 0.4 24 5.2 0.9 2.9 2 1 0 2 2 2 0 AAA domain DUF1642 PF07852.6 EOO02477.1 - 0.052 13.8 0.1 1.5 9.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1642) BetaGal_dom3 PF13363.1 EOO02477.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 MobB PF03205.9 EOO02477.1 - 0.061 13.0 2.0 4 7.1 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AKAP95 PF04988.7 EOO02477.1 - 0.062 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) AAA_17 PF13207.1 EOO02477.1 - 0.067 14.0 0.1 0.5 11.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EOO02477.1 - 0.085 12.6 0.3 5.5 6.7 0.0 3.0 1 1 1 3 3 3 0 Dynamin family Minor_capsid_1 PF10665.4 EOO02477.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein SnoaL_2 PF12680.2 EOO02479.1 - 0.0081 16.5 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain Alpha-amylase PF00128.19 EOO02480.1 - 4.9e-27 95.1 0.0 8.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EOO02480.1 - 3.4e-07 30.2 0.2 2.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Abi_2 PF07751.6 EOO02480.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Abi-like protein FTA2 PF13095.1 EOO02481.1 - 4e-16 59.2 0.0 6.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ppx-GppA PF02541.11 EOO02482.1 - 3.7e-32 111.6 0.0 7e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Peptidase_S8 PF00082.17 EOO02483.1 - 1.3e-18 67.1 0.0 1.6e-18 66.8 0.0 1.3 1 1 0 1 1 1 1 Subtilase family Nsp1_C PF05064.8 EOO02484.1 - 3.4e-35 120.2 7.9 3.4e-35 120.2 5.5 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region Myosin_tail_1 PF01576.14 EOO02484.1 - 0.0013 16.5 7.2 0.007 14.1 5.0 1.8 1 1 0 1 1 1 1 Myosin tail Lipoprotein_6 PF01441.14 EOO02484.1 - 0.0024 17.7 1.7 0.013 15.4 0.2 2.2 1 1 1 2 2 2 1 Lipoprotein NPV_P10 PF05531.7 EOO02484.1 - 0.0029 17.8 3.9 2.7 8.3 0.0 3.4 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 EOO02484.1 - 0.004 15.4 6.6 0.024 12.8 0.0 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.7 EOO02484.1 - 0.011 15.5 4.0 0.31 10.8 0.0 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 EOO02484.1 - 0.012 14.9 14.8 0.24 10.6 6.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EOO02484.1 - 0.012 14.7 1.4 0.21 10.7 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EOO02484.1 - 0.013 15.3 7.5 0.056 13.3 4.8 2.2 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.11 EOO02484.1 - 0.016 15.2 1.5 0.016 15.2 1.0 2.4 3 0 0 3 3 3 0 Flagellar FliJ protein DUF1664 PF07889.7 EOO02484.1 - 0.025 14.3 3.1 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EOO02484.1 - 0.028 14.7 4.1 0.19 12.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 EOO02484.1 - 0.035 13.2 3.8 0.041 13.0 2.6 1.2 1 0 0 1 1 1 0 TMCO5 family MCPsignal PF00015.16 EOO02484.1 - 0.046 13.2 2.8 0.81 9.1 0.1 2.1 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 EOO02484.1 - 0.056 12.7 6.3 0.055 12.7 3.6 1.5 1 1 0 1 1 1 0 Laminin Domain I APG6 PF04111.7 EOO02484.1 - 0.061 12.3 7.3 0.19 10.7 5.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EOO02484.1 - 0.063 12.4 5.8 8.2 5.5 0.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HSBP1 PF06825.7 EOO02484.1 - 0.081 12.5 2.2 0.33 10.5 0.3 2.7 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF2315 PF10231.4 EOO02484.1 - 0.091 12.6 1.4 0.24 11.2 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) DOG1 PF14144.1 EOO02484.1 - 0.094 12.7 1.5 13 5.8 0.0 2.9 2 1 1 3 3 3 0 Seed dormancy control Spc7 PF08317.6 EOO02484.1 - 0.1 11.2 7.0 0.66 8.5 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4435 PF14491.1 EOO02484.1 - 0.13 12.0 1.2 0.15 11.9 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) DUF2203 PF09969.4 EOO02484.1 - 0.14 12.4 0.9 0.52 10.5 0.2 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF641 PF04859.7 EOO02484.1 - 0.15 11.8 4.9 0.072 12.8 0.5 2.3 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) ERM PF00769.14 EOO02484.1 - 0.15 11.5 7.2 0.071 12.6 3.2 1.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V-SNARE PF05008.10 EOO02484.1 - 0.16 12.1 7.2 0.53 10.4 0.9 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Synaptonemal_3 PF15191.1 EOO02484.1 - 0.16 11.7 1.2 0.29 10.8 0.1 2.0 2 1 0 2 2 1 0 Synaptonemal complex central element protein 3 CorA PF01544.13 EOO02484.1 - 0.2 10.6 4.3 4.3 6.2 1.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EOO02484.1 - 0.23 11.0 7.4 0.65 9.5 5.3 1.8 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EOO02484.1 - 0.26 9.7 6.9 0.57 8.5 4.8 1.5 1 1 0 1 1 1 0 AAA domain Tropomyosin PF00261.15 EOO02484.1 - 0.3 10.1 8.2 3.1 6.8 5.5 2.1 1 1 0 1 1 1 0 Tropomyosin ING PF12998.2 EOO02484.1 - 0.33 11.2 4.9 7.2 6.9 1.5 2.6 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding COG2 PF06148.6 EOO02484.1 - 0.35 10.7 4.0 6.5 6.6 0.6 3.2 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EOO02484.1 - 0.62 9.8 6.1 3.5 7.3 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF948 PF06103.6 EOO02484.1 - 0.78 9.6 3.1 8.6 6.2 0.0 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EOO02484.1 - 0.82 7.4 4.9 5.3 4.7 2.7 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 EOO02484.1 - 0.95 9.6 6.9 0.71 10.0 1.2 2.7 3 1 0 3 3 2 0 Domain of unknown function (DUF4164) ParB PF08775.5 EOO02484.1 - 1.4 9.2 4.3 6.8 7.0 0.1 2.3 2 1 0 2 2 2 0 ParB family Syntaxin-6_N PF09177.6 EOO02484.1 - 3 8.3 7.5 7.9 6.9 3.8 2.7 1 1 3 4 4 3 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 EOO02484.1 - 3.3 7.6 9.6 4.1 7.3 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EOO02484.1 - 3.7 7.6 8.4 5.4 7.0 0.1 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EOO02484.1 - 4.2 7.1 10.2 10 5.8 2.5 3.2 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.4 EOO02484.1 - 7.5 6.7 8.4 26 5.0 1.7 2.9 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 EOO02484.1 - 9.7 5.9 13.1 2.6 7.7 5.6 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SASP_gamma PF04259.9 EOO02484.1 - 9.9 6.3 8.2 4.1 7.6 0.4 2.3 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type 14-3-3 PF00244.15 EOO02485.1 - 2.6e-116 386.7 2.6 3.1e-116 386.5 1.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 EOO02485.1 - 0.051 13.3 0.1 0.19 11.4 0.0 2.1 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF837 PF05769.6 EOO02485.1 - 0.1 12.1 1.5 6.5 6.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Pkinase PF00069.20 EOO02486.1 - 5.7e-08 32.2 0.0 5.1e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02486.1 - 0.0011 18.1 0.0 0.33 9.9 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase MFS_1 PF07690.11 EOO02487.1 - 3.4e-14 52.3 58.8 6.7e-09 34.9 22.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO02487.1 - 9e-05 20.8 15.3 0.00017 19.9 10.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 EOO02487.1 - 0.00016 20.5 15.6 0.0004 19.2 7.7 2.6 2 1 0 3 3 3 2 PUCC protein adh_short_C2 PF13561.1 EOO02488.1 - 1.3e-35 123.3 0.2 1.6e-35 123.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO02488.1 - 9.6e-25 87.4 1.3 1.3e-24 86.9 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02488.1 - 3.6e-11 43.0 0.3 5.2e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EOO02488.1 - 0.00014 21.4 0.1 0.00023 20.8 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.16 EOO02488.1 - 0.0026 17.2 0.2 0.01 15.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 EOO02488.1 - 0.0078 15.4 0.5 0.012 14.8 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NADH5_C PF06455.6 EOO02488.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus adh_short_C2 PF13561.1 EOO02489.1 - 4.9e-29 101.8 0.1 6e-27 94.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO02489.1 - 5.6e-20 71.9 1.4 1.7e-19 70.3 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02489.1 - 3.3e-09 36.6 0.2 6.1e-09 35.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO02489.1 - 1.6e-06 27.7 0.2 0.0032 16.9 0.2 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family DUF3546 PF12066.3 EOO02490.1 - 5.8e-28 97.0 0.5 5.8e-28 97.0 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EOO02490.1 - 9.5e-25 85.9 0.1 2.4e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EOO02490.1 - 3.9e-13 50.0 0.5 9.3e-13 48.8 0.4 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 RCR PF12273.3 EOO02491.1 - 5.7e-25 88.3 7.6 7.8e-25 87.9 5.3 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EOO02491.1 - 0.00011 21.9 0.6 0.00013 21.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Orthoreo_P10 PF07204.6 EOO02491.1 - 0.052 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Rhabdo_glycop PF00974.13 EOO02491.1 - 0.14 10.3 0.9 0.22 9.7 0.6 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PROL5-SMR PF15621.1 EOO02491.1 - 2.5 8.5 13.1 22 5.5 9.2 2.0 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DEAD PF00270.24 EOO02492.1 - 3.9e-43 146.8 0.0 1.3e-41 141.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO02492.1 - 1.5e-25 88.8 0.1 3.2e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EOO02492.1 - 0.54 9.7 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Corona_S2 PF01601.11 EOO02493.1 - 10 4.1 19.7 14 3.6 13.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ATP-synt_F6 PF05511.6 EOO02494.1 - 0.067 13.0 0.1 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 WAC_Acf1_DNA_bd PF10537.4 EOO02494.1 - 0.21 11.7 2.7 0.39 10.9 1.1 1.9 1 1 1 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal FAD_binding_3 PF01494.14 EOO02495.1 - 3.3e-17 62.5 0.1 2e-16 60.0 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO02495.1 - 2.5e-05 23.3 0.2 0.025 13.5 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EOO02495.1 - 0.00049 20.4 0.1 0.0033 17.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO02495.1 - 0.026 14.5 0.1 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SAM_MT PF04445.8 EOO02495.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase RNA_pol PF00940.14 EOO02496.1 - 3.2e-163 542.9 0.0 4.8e-163 542.3 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EOO02496.1 - 5.9e-79 265.5 0.4 1.2e-78 264.5 0.2 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.9 EOO02497.1 - 1.9e-27 95.9 0.1 2.8e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EOO02497.1 - 1.1e-07 31.5 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 DHH family Oligomerisation PF02410.10 EOO02498.1 - 0.0026 17.7 0.0 0.034 14.1 0.0 2.6 2 0 0 2 2 2 1 Oligomerisation domain S1-P1_nuclease PF02265.11 EOO02499.1 - 4e-74 249.4 0.2 4.5e-74 249.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GATase PF00117.23 EOO02500.1 - 4.5e-11 42.5 0.0 5.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMC_oxred_N PF00732.14 EOO02501.1 - 8e-53 179.4 0.0 1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO02501.1 - 1.4e-33 116.2 0.0 2.3e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EOO02501.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EOO02501.1 - 0.007 15.2 2.2 1.9 7.2 1.6 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EOO02501.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO02501.1 - 0.18 11.8 0.5 0.46 10.5 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ring_hydroxyl_A PF00848.14 EOO02502.1 - 1.9e-25 89.7 1.5 5.4e-17 62.1 1.1 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EOO02502.1 - 1.8e-14 53.0 0.1 4e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rhabdo_glycop PF00974.13 EOO02502.1 - 0.015 13.6 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein FAD_binding_3 PF01494.14 EOO02504.1 - 1.8e-27 96.3 0.6 4.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EOO02504.1 - 1.9e-06 27.0 0.0 0.043 12.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EOO02504.1 - 7.8e-05 21.4 0.4 0.11 11.0 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EOO02504.1 - 0.0005 20.0 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EOO02504.1 - 0.00059 18.4 0.0 0.094 11.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EOO02504.1 - 0.0012 18.4 0.1 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EOO02504.1 - 0.0014 18.9 0.0 0.024 15.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO02504.1 - 0.034 14.0 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EOO02504.1 - 0.057 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.11 EOO02505.1 - 7.2e-39 133.4 51.0 4.5e-38 130.8 35.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 EOO02506.1 - 4.4e-12 46.4 0.0 7.1e-08 32.8 0.0 3.4 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EOO02506.1 - 1.8e-09 37.9 2.3 0.0026 17.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EOO02506.1 - 4e-05 23.6 4.5 0.0021 18.0 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DnaJ_CXXCXGXG PF00684.14 EOO02506.1 - 4.3e-05 23.4 2.1 0.018 15.0 0.1 3.2 3 0 0 3 3 3 1 DnaJ central domain SMC_N PF02463.14 EOO02506.1 - 0.0021 17.3 0.0 13 4.9 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EOO02506.1 - 0.0054 16.2 0.1 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EOO02506.1 - 0.009 15.4 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EOO02506.1 - 0.015 16.1 0.0 0.072 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EOO02506.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 EOO02506.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EOO02506.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EOO02506.1 - 0.027 14.1 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 1 0 Part of AAA domain ArgK PF03308.11 EOO02506.1 - 0.031 13.0 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Viral_helicase1 PF01443.13 EOO02506.1 - 0.043 13.3 0.1 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EOO02506.1 - 0.065 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EOO02506.1 - 0.084 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EOO02506.1 - 0.096 12.3 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EOO02506.1 - 0.1 12.7 0.0 0.4 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EOO02506.1 - 0.11 11.4 0.0 34 3.3 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Catalase PF00199.14 EOO02507.1 - 9.4e-88 294.4 0.4 1.1e-87 294.1 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EOO02507.1 - 4.7e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive PTR2 PF00854.16 EOO02508.1 - 1.9e-33 115.7 16.5 8.6e-17 60.9 0.1 3.1 1 1 1 3 3 3 2 POT family DUF1469 PF07332.6 EOO02508.1 - 0.0011 18.6 0.2 0.0011 18.6 0.2 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1469) CcmH PF03918.9 EOO02508.1 - 0.056 12.4 0.7 5.3 6.0 0.0 2.6 2 1 0 2 2 2 0 Cytochrome C biogenesis protein Tmemb_170 PF10190.4 EOO02508.1 - 1.9 8.5 8.4 6.9 6.7 0.3 3.3 3 0 0 3 3 3 0 Putative transmembrane protein 170 AA_permease PF00324.16 EOO02509.1 - 7.9e-97 324.5 38.9 9.8e-97 324.2 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO02509.1 - 1.3e-26 93.1 45.0 1.6e-26 92.7 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1680 PF07944.7 EOO02510.1 - 1.2e-93 314.1 0.0 2e-93 313.4 0.0 1.3 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_transf_28 PF03033.15 EOO02511.1 - 2e-19 69.7 0.0 2.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain F-box PF00646.28 EOO02512.1 - 0.0023 17.5 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EOO02512.1 - 0.008 15.8 0.1 0.026 14.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like OPT PF03169.10 EOO02514.1 - 6.1e-160 533.6 46.8 7.3e-160 533.4 32.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ATP-synt_8 PF00895.15 EOO02514.1 - 2 8.7 12.2 7.5 6.8 2.9 3.3 2 0 0 2 2 2 0 ATP synthase protein 8 DAO PF01266.19 EOO02515.1 - 4.6e-30 104.7 0.0 8e-30 103.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_C PF05199.8 EOO02516.1 - 5.5e-21 75.3 0.0 7.9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Hydantoinase_B PF02538.9 EOO02517.1 - 2.2e-108 362.8 0.1 3e-108 362.3 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO02517.1 - 8.2e-92 307.3 0.3 1.8e-91 306.2 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO02517.1 - 3.2e-56 189.6 0.3 1.9e-54 183.8 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region BRCT_assoc PF12820.2 EOO02518.1 - 0.012 15.3 0.4 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Spc7 PF08317.6 EOO02518.1 - 0.11 11.1 5.0 0.12 11.0 3.5 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein SseC PF04888.7 EOO02518.1 - 0.44 9.8 5.6 0.49 9.6 3.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TMCO5 PF14992.1 EOO02518.1 - 0.62 9.1 7.2 0.63 9.1 5.0 1.0 1 0 0 1 1 1 0 TMCO5 family Rrp15p PF07890.7 EOO02518.1 - 1.1 9.2 6.6 1.3 9.1 4.5 1.1 1 0 0 1 1 1 0 Rrp15p DUF3552 PF12072.3 EOO02518.1 - 3.5 6.7 9.9 4.1 6.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DAO PF01266.19 EOO02519.1 - 3.2e-60 203.9 0.3 4.7e-60 203.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EOO02519.1 - 8.2e-53 178.8 0.0 1.5e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EOO02519.1 - 2.9e-17 62.4 0.1 9.3e-17 60.8 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.22 EOO02519.1 - 1.2e-05 25.5 0.2 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO02519.1 - 0.00061 18.7 0.2 0.00093 18.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 EOO02519.1 - 0.00077 19.4 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.1 EOO02519.1 - 0.003 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EOO02519.1 - 0.0053 15.4 0.2 0.023 13.3 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase SoxG PF04268.7 EOO02519.1 - 0.0059 16.4 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family NAD_binding_8 PF13450.1 EOO02519.1 - 0.008 16.1 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EOO02519.1 - 0.03 14.1 0.1 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 EOO02519.1 - 0.036 13.8 0.1 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EOO02519.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EOO02519.1 - 0.11 11.3 0.2 1.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EOO02519.1 - 0.12 11.4 0.5 0.81 8.6 0.3 2.0 1 1 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EOO02519.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EOO02520.1 - 2.2e-66 223.9 1.9 2.8e-66 223.6 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EOO02520.1 - 1.4e-59 201.6 0.2 1.4e-59 201.6 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 EOO02520.1 - 8.8e-59 198.1 0.0 2.2e-58 196.9 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EOO02520.1 - 1.1e-48 166.1 0.3 2.1e-48 165.3 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EOO02520.1 - 4.5e-46 156.8 0.1 2.8e-45 154.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EOO02520.1 - 1.8e-39 134.2 0.0 5.4e-39 132.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EOO02520.1 - 1.8e-16 60.4 0.0 5.8e-16 58.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EOO02520.1 - 1.8e-12 46.9 0.0 1.8e-12 46.9 0.0 3.0 3 1 1 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EOO02520.1 - 1.9e-11 43.9 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EOO02520.1 - 2.5e-11 44.5 0.1 1.4e-10 42.0 0.0 2.5 1 1 1 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EOO02520.1 - 2.4e-06 28.0 0.0 1.7e-05 25.3 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EOO02520.1 - 5.6e-06 26.0 0.1 1.2e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EOO02520.1 - 7.1e-06 26.4 0.1 7e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02520.1 - 9.1e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EOO02520.1 - 0.00011 22.3 1.0 0.00025 21.2 0.4 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 EOO02520.1 - 0.00036 20.5 0.2 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO02520.1 - 0.027 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EOO02520.1 - 0.055 14.3 0.0 0.2 12.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain LEM PF03020.10 EOO02520.1 - 0.056 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 LEM domain Polysacc_synt_2 PF02719.10 EOO02520.1 - 0.38 9.6 0.0 0.64 8.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IU_nuc_hydro PF01156.14 EOO02521.1 - 2e-31 109.4 0.0 2.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.11 EOO02522.1 - 1.1e-29 103.3 12.5 1.4e-29 102.9 8.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 EOO02522.1 - 0.0019 17.6 0.6 0.0019 17.6 0.4 2.8 2 1 0 2 2 2 1 7TM receptor with intracellular HD hydrolase DUF2408 PF10303.4 EOO02523.1 - 0.086 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FRG2 PF15315.1 EOO02523.1 - 0.46 10.4 7.7 0.6 10.0 5.3 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Reo_sigmaC PF04582.7 EOO02524.1 - 0.014 14.5 0.4 0.021 14.0 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EOO02524.1 - 0.12 12.2 0.5 0.85 9.4 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 EOO02524.1 - 0.12 12.3 1.6 0.47 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2732 PF10809.3 EOO02524.1 - 0.51 9.9 4.3 0.2 11.2 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) IncA PF04156.9 EOO02524.1 - 1.6 8.2 7.0 7.3 6.1 4.8 1.9 1 1 0 1 1 1 0 IncA protein TPP_enzyme_N PF02776.13 EOO02525.1 - 3.2e-34 117.9 0.0 5.5e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EOO02525.1 - 9.1e-15 54.5 0.1 2.4e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EOO02525.1 - 2.2e-12 46.8 0.0 5.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.15 EOO02525.1 - 0.03 13.0 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Histone PF00125.19 EOO02526.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EOO02526.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.26 EOO02527.1 - 3.6e-25 87.4 3.2 1.1e-24 85.9 2.3 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EOO02527.1 - 1.1e-13 50.6 2.8 1.7e-08 33.9 0.0 5.3 3 3 1 6 6 6 2 TPR repeat TPR_14 PF13428.1 EOO02527.1 - 3.4e-11 42.7 1.5 0.061 13.9 0.1 6.2 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EOO02527.1 - 5.5e-11 41.5 4.3 0.024 14.5 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EOO02527.1 - 6.8e-11 42.5 2.5 0.00075 20.0 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EOO02527.1 - 8.3e-11 41.0 0.1 0.00046 19.6 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EOO02527.1 - 1.3e-10 40.3 0.1 0.0015 18.1 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EOO02527.1 - 1.3e-08 34.5 0.1 0.0001 22.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EOO02527.1 - 3e-06 27.3 5.2 2 9.0 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EOO02527.1 - 6.1e-06 26.4 4.1 0.0078 16.5 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EOO02527.1 - 5e-05 23.1 1.2 0.047 13.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EOO02527.1 - 6.9e-05 22.3 3.9 0.42 10.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EOO02527.1 - 0.00069 19.4 3.2 0.016 15.1 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat SLS PF14611.1 EOO02527.1 - 0.0012 18.3 0.2 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator TPR_15 PF13429.1 EOO02527.1 - 0.012 14.6 3.6 3.6 6.5 0.0 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EOO02527.1 - 0.029 14.4 0.5 3.7 7.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIF4G PF02854.14 EOO02528.1 - 9.9e-24 83.9 0.5 2.5e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EOO02528.1 - 2.3e-16 59.4 0.0 6.7e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 MA3 domain Pyr_redox_dim PF02852.17 EOO02529.1 - 1.4e-39 134.4 0.0 5.3e-39 132.6 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EOO02529.1 - 1.3e-37 129.6 11.7 6.5e-36 124.0 8.1 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO02529.1 - 3.4e-25 88.2 12.0 1.1e-21 76.9 1.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO02529.1 - 6.9e-12 45.2 2.4 3.2e-06 27.0 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EOO02529.1 - 1.5e-10 40.8 4.8 8.9e-10 38.2 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EOO02529.1 - 2.5e-10 39.7 3.3 5e-08 32.2 0.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EOO02529.1 - 2.4e-09 36.5 7.2 2.9e-07 29.6 1.8 3.2 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 EOO02529.1 - 2.7e-09 37.4 1.7 0.0001 22.4 0.4 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO02529.1 - 1.1e-07 31.0 18.8 8.3e-05 21.6 1.3 4.0 2 2 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.12 EOO02529.1 - 1.3e-06 27.7 5.7 4.1e-05 22.8 0.4 2.5 2 1 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EOO02529.1 - 1.3e-06 27.1 13.4 5.8e-05 21.7 1.2 4.1 4 1 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EOO02529.1 - 9.7e-05 21.4 0.3 0.31 9.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EOO02529.1 - 0.00032 20.3 3.4 0.36 10.3 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EOO02529.1 - 0.00068 18.6 1.8 0.013 14.4 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EOO02529.1 - 0.002 17.2 11.0 0.096 11.7 0.9 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 EOO02529.1 - 0.0046 17.1 5.2 2.5 8.3 0.1 3.6 2 1 0 3 3 3 2 Putative NAD(P)-binding FMO-like PF00743.14 EOO02529.1 - 0.09 10.9 0.6 0.17 10.0 0.4 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EOO02529.1 - 0.093 11.3 6.4 0.052 12.1 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 EOO02529.1 - 0.094 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EOO02529.1 - 0.65 9.6 8.5 0.25 10.9 0.2 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C14 PF00656.17 EOO02530.1 - 6.9e-72 242.1 0.0 8.6e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF605 PF04652.11 EOO02530.1 - 2.5 7.4 11.8 3.9 6.7 8.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF2410 PF10307.4 EOO02531.1 - 4.7e-80 267.6 0.0 6.3e-80 267.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Pkinase PF00069.20 EOO02532.1 - 7.6e-68 228.4 0.0 1.1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02532.1 - 7.9e-28 97.2 0.1 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02532.1 - 0.00059 18.8 0.0 0.00098 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO02532.1 - 0.0019 17.3 0.1 0.0031 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EOO02532.1 - 0.0097 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EOO02532.1 - 0.046 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 EOO02532.1 - 0.077 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 EOO02532.1 - 0.099 11.9 0.3 0.35 10.2 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain PH PF00169.24 EOO02533.1 - 3.3e-10 40.1 0.0 6.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EOO02533.1 - 0.013 13.0 0.5 0.019 12.4 0.3 1.1 1 0 0 1 1 1 0 Prominin Gar1 PF04410.9 EOO02534.1 - 1.7e-42 144.4 0.2 1.7e-42 144.4 0.1 2.1 1 1 1 2 2 2 2 Gar1/Naf1 RNA binding region Cys_Met_Meta_PP PF01053.15 EOO02535.1 - 1.7e-38 131.9 0.0 2.1e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EOO02535.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Glyoxalase_2 PF12681.2 EOO02536.1 - 0.0099 16.4 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain APG9 PF04109.11 EOO02537.1 - 3.3e-119 398.0 2.0 4.5e-119 397.6 1.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 PGG PF13962.1 EOO02537.1 - 0.13 11.8 1.0 0.84 9.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function RTA1 PF04479.8 EOO02538.1 - 2.1e-18 66.6 3.7 3.5e-18 65.9 2.5 1.3 1 0 0 1 1 1 1 RTA1 like protein Mito_carr PF00153.22 EOO02539.1 - 4.2e-50 167.4 2.4 2.7e-23 81.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1917 PF08939.5 EOO02540.1 - 2.1e-58 197.9 2.4 3.1e-56 190.8 1.7 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Histone PF00125.19 EOO02542.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EOO02542.1 - 3.8e-05 23.6 0.0 9.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EOO02542.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EOO02542.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EOO02542.1 - 0.031 14.7 0.6 0.042 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) FA_desaturase PF00487.19 EOO02543.1 - 1.7e-35 122.7 27.0 2.5e-35 122.1 18.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EOO02543.1 - 1.6e-13 50.2 0.1 3.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xpo1 PF08389.7 EOO02544.1 - 7.2e-07 29.2 0.1 1.2e-05 25.2 0.1 3.0 1 1 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 EOO02544.1 - 0.0016 18.2 0.3 0.018 14.9 0.1 3.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain TH1 PF04858.8 EOO02544.1 - 0.14 10.2 0.0 0.23 9.5 0.0 1.2 1 0 0 1 1 1 0 TH1 protein MFS_1 PF07690.11 EOO02546.1 - 7.1e-32 110.4 28.6 7.1e-32 110.4 19.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.16 EOO02546.1 - 4.6e-12 46.1 1.8 4.6e-12 46.1 1.2 2.8 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Rifin_STEVOR PF02009.11 EOO02546.1 - 0.21 11.2 0.3 0.35 10.4 0.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family Fungal_trans_2 PF11951.3 EOO02547.1 - 1.3e-05 24.0 2.7 1.4e-05 23.8 0.9 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 EOO02548.1 - 1.8e-58 197.2 0.0 3e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 N6-adenineMlase PF10237.4 EOO02549.1 - 2.8e-59 199.4 0.0 6.5e-59 198.2 0.0 1.6 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NAD_binding_10 PF13460.1 EOO02549.1 - 6.1e-11 42.6 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO02549.1 - 1e-09 38.0 0.0 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EOO02549.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO02549.1 - 6.5e-07 28.3 0.0 1.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EOO02549.1 - 0.00026 19.9 0.1 0.0092 14.9 0.0 2.7 2 1 0 2 2 2 1 RmlD substrate binding domain COQ9 PF08511.6 EOO02551.1 - 1.1e-30 104.9 0.0 1.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 COQ9 RNA_pol_Rpb2_4 PF04566.8 EOO02551.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Whi5 PF08528.6 EOO02552.1 - 1e-10 40.8 0.1 1.9e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Whi5 like LCAT PF02450.10 EOO02553.1 - 1.1e-97 327.4 0.1 1.4e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EOO02553.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EOO02553.1 - 0.074 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.5 EOO02553.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lactamase_B PF00753.22 EOO02554.1 - 5.3e-20 71.8 0.1 7.6e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EOO02554.1 - 0.0002 20.9 0.1 0.00034 20.2 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HTH_Crp_2 PF13545.1 EOO02554.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HemN_C PF06969.11 EOO02554.1 - 0.039 14.0 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 HemN C-terminal domain DUF2013 PF09431.5 EOO02555.1 - 1.1e-52 177.5 0.8 1.1e-52 177.5 0.6 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF2013) W2 PF02020.13 EOO02556.1 - 2.6e-18 65.7 2.1 2.6e-18 65.7 1.5 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EOO02556.1 - 8e-07 28.3 8.5 0.0026 17.2 1.4 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EOO02556.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase BRK PF07533.11 EOO02556.1 - 0.005 16.2 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 BRK domain Hexapep_2 PF14602.1 EOO02556.1 - 0.0077 15.7 5.8 0.83 9.2 1.1 3.0 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EOO02556.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Microtub_assoc PF07989.6 EOO02557.1 - 1.7e-28 98.2 4.7 1.7e-28 98.2 3.2 13.2 9 3 4 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 EOO02557.1 - 2.2e-08 33.9 5.0 3.2e-07 30.1 3.5 2.6 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein AAA_13 PF13166.1 EOO02557.1 - 5.3e-05 21.9 146.1 0.00029 19.4 19.3 6.3 1 1 6 7 7 7 6 AAA domain MscS_porin PF12795.2 EOO02557.1 - 0.00028 20.2 17.4 0.00028 20.2 12.1 8.7 1 1 5 8 8 8 3 Mechanosensitive ion channel porin domain Leu_zip PF15294.1 EOO02557.1 - 0.00082 18.5 14.1 0.00082 18.5 9.8 7.7 2 2 5 7 7 6 1 Leucine zipper Reo_sigmaC PF04582.7 EOO02557.1 - 0.0025 17.0 64.6 0.0029 16.8 3.2 8.5 2 2 7 9 9 9 5 Reovirus sigma C capsid protein TBPIP PF07106.8 EOO02557.1 - 0.0027 17.2 7.3 0.0027 17.2 5.1 12.4 4 1 10 14 14 14 5 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EOO02557.1 - 0.0042 16.8 19.3 0.0042 16.8 13.4 13.2 6 3 7 13 13 13 8 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EOO02557.1 - 0.0044 16.8 205.7 0.22 11.3 13.7 11.3 3 3 7 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EOO02557.1 - 0.0074 16.0 5.5 0.0074 16.0 3.8 12.0 5 3 6 13 13 13 3 Protein of unknown function (DUF1664) DUF4200 PF13863.1 EOO02557.1 - 0.008 16.1 13.4 0.008 16.1 9.3 13.4 4 2 9 14 14 13 1 Domain of unknown function (DUF4200) SPX PF03105.14 EOO02558.1 - 5.2e-43 147.8 1.7 6.3e-43 147.5 1.2 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EOO02558.1 - 1.9e-07 30.8 9.5 1.9e-07 30.8 6.6 2.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EOO02558.1 - 3e-07 30.1 12.2 5.9e-07 29.2 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EOO02558.1 - 6.2e-07 28.9 10.9 1.4e-06 27.8 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EOO02558.1 - 5.3e-06 26.0 9.3 1e-05 25.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO02558.1 - 6.2e-06 26.1 12.5 1.3e-05 25.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02558.1 - 7.6e-05 22.3 11.5 0.00027 20.5 8.1 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EOO02558.1 - 0.014 15.0 9.3 0.014 15.0 6.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EOO02558.1 - 0.016 15.3 4.5 0.033 14.3 3.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EOO02558.1 - 0.04 13.7 3.8 0.074 12.8 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EOO02558.1 - 0.12 12.0 9.8 0.026 14.1 3.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EOO02558.1 - 0.37 10.6 6.3 1.3 8.8 4.2 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF1644 PF07800.7 EOO02558.1 - 1.2 8.9 6.6 1.6 8.5 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) COG6 PF06419.6 EOO02559.1 - 2.4e-199 663.5 4.7 2.7e-199 663.3 3.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 ArsC PF03960.10 EOO02559.1 - 1.5 8.9 4.1 32 4.6 0.0 3.3 4 0 0 4 4 4 0 ArsC family DUF1835 PF08874.5 EOO02560.1 - 0.0095 15.8 0.2 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1835) DUF3888 PF13027.1 EOO02560.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) TMEMspv1-c74-12 PF11044.3 EOO02560.1 - 4.2 7.0 6.0 1.1 8.8 0.6 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein tRNA-synt_2b PF00587.20 EOO02561.1 - 1.6e-43 148.2 0.8 2.7e-43 147.5 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EOO02561.1 - 2.1e-20 72.4 0.4 4.6e-20 71.3 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EOO02561.1 - 1e-12 47.7 0.0 2.2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EOO02561.1 - 5.4e-11 42.1 0.0 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 TGS domain SMC_N PF02463.14 EOO02562.1 - 6e-21 74.6 15.2 9.8e-20 70.7 10.6 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EOO02562.1 - 5e-12 46.5 21.1 5e-12 46.5 14.7 5.0 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EOO02562.1 - 3.1e-07 30.6 0.2 0.00026 21.0 0.2 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EOO02562.1 - 0.00062 18.9 0.1 0.00062 18.9 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EOO02562.1 - 0.00072 19.0 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EOO02562.1 - 0.00075 19.3 0.0 0.0033 17.3 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EOO02562.1 - 0.051 12.7 15.8 0.069 12.3 0.1 4.5 3 2 2 5 5 5 0 Reovirus sigma C capsid protein TLD PF07534.11 EOO02563.1 - 5.1e-25 88.0 0.0 1.8e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 TLD HEM4 PF02602.10 EOO02563.1 - 6.8e-22 77.8 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Rubella_E2 PF05749.6 EOO02563.1 - 0.26 10.5 4.3 5.2 6.2 0.2 2.7 2 1 0 2 2 2 0 Rubella membrane glycoprotein E2 Ytp1 PF10355.4 EOO02564.1 - 6.8e-115 382.9 8.0 1.1e-114 382.2 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EOO02564.1 - 8e-35 118.5 11.5 1.1e-34 118.1 3.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) KduI PF04962.7 EOO02564.1 - 0.044 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Acetyltransf_1 PF00583.19 EOO02565.1 - 1.6e-19 69.7 0.0 2.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EOO02565.1 - 1.8e-10 40.9 0.0 2.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EOO02565.1 - 2.7e-10 39.8 0.0 4.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EOO02565.1 - 4.2e-10 39.6 0.0 6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EOO02565.1 - 1.3e-08 35.0 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO02565.1 - 4e-08 33.2 0.0 4.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EOO02565.1 - 3.5e-05 23.6 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EOO02565.1 - 0.00051 19.8 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Aconitase PF00330.15 EOO02566.1 - 6e-174 578.9 0.0 1e-173 578.1 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EOO02566.1 - 8.7e-45 152.0 0.0 1.5e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain 2-oxoacid_dh PF00198.18 EOO02567.1 - 6.8e-79 264.3 0.1 9.7e-79 263.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EOO02567.1 - 8.3e-19 67.0 1.8 1.5e-18 66.1 1.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EOO02567.1 - 0.0039 16.4 2.4 0.042 12.9 0.2 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EOO02567.1 - 0.016 14.8 0.6 0.57 9.8 0.1 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.1 EOO02567.1 - 0.016 15.5 0.3 0.12 12.7 0.2 2.1 1 1 0 1 1 1 0 HlyD family secretion protein RR_TM4-6 PF06459.7 EOO02567.1 - 3.4 7.4 9.6 4.9 6.9 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vac14_Fig4_bd PF11916.3 EOO02568.1 - 8.2e-57 191.2 4.0 1.5e-56 190.4 2.8 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EOO02568.1 - 1.6e-08 34.8 3.5 0.0092 16.3 0.1 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EOO02568.1 - 0.11 13.0 5.4 1.9 9.1 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.17 EOO02568.1 - 0.15 12.2 3.6 11 6.3 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat CENP-B_dimeris PF09026.5 EOO02568.1 - 0.23 11.7 4.1 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain G-patch PF01585.18 EOO02569.1 - 6.2e-12 45.1 2.0 1.3e-11 44.0 1.4 1.6 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EOO02569.1 - 2e-11 43.4 0.0 4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EOO02569.1 - 0.027 14.3 1.0 0.027 14.3 0.7 2.5 3 0 0 3 3 3 0 DExH-box splicing factor binding site Gaa1 PF04114.9 EOO02570.1 - 7.7e-95 318.4 0.1 9.2e-95 318.2 0.1 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rsa3 PF14615.1 EOO02571.1 - 7.5e-21 73.1 0.7 9.4e-21 72.8 0.5 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UCH PF00443.24 EOO02572.1 - 5.4e-58 196.2 2.7 7.5e-58 195.7 1.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EOO02572.1 - 6.4e-36 124.2 1.3 8.6e-36 123.8 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EOO02572.1 - 5.2e-05 23.2 0.2 5.2e-05 23.2 0.2 2.6 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-CCHC PF00098.18 EOO02572.1 - 2.3 8.3 10.2 4.7 7.3 0.1 4.3 4 0 0 4 4 4 0 Zinc knuckle SGT1 PF07093.6 EOO02573.1 - 1.2e-145 486.2 35.7 3.9e-144 481.2 24.7 2.0 1 1 0 1 1 1 1 SGT1 protein PAS_9 PF13426.1 EOO02574.1 - 2.3e-31 108.2 0.0 2.1e-17 63.3 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EOO02574.1 - 1.7e-18 66.5 0.0 1.6e-11 44.1 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 EOO02574.1 - 1e-15 57.4 0.0 8.2e-07 28.7 0.0 4.1 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 EOO02574.1 - 4.9e-15 54.5 9.1 1.2e-14 53.3 6.3 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EOO02574.1 - 3.4e-10 39.8 0.0 0.00023 21.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EOO02574.1 - 8.2e-07 29.0 0.0 0.073 13.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.6 EOO02574.1 - 0.00029 21.2 0.0 2.2 8.7 0.0 3.4 3 0 0 3 3 3 1 PAS fold PCI PF01399.22 EOO02576.1 - 6.8e-10 39.1 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain COX5A PF02284.11 EOO02576.1 - 0.06 13.3 0.1 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va EMG1 PF03587.9 EOO02577.1 - 2e-79 265.6 0.0 2.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase zf-C2H2_jaz PF12171.3 EOO02578.1 - 6.4e-10 38.8 0.2 1.1e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EOO02578.1 - 0.031 14.1 0.2 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EOO02578.1 - 0.067 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EOO02578.1 - 0.077 13.3 0.2 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.7 EOO02578.1 - 0.12 11.9 0.2 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 U1 zinc finger Transglut_core2 PF13369.1 EOO02579.1 - 2.6e-15 56.2 0.0 5.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EOO02579.1 - 1.3e-06 28.0 1.0 2.6e-06 27.0 0.7 1.6 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 EOO02579.1 - 8.5e-05 22.4 6.3 0.00013 21.8 1.2 2.9 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 EOO02579.1 - 0.00077 19.0 0.3 0.0016 17.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain Med15 PF09606.5 EOO02580.1 - 0.03 12.5 48.8 0.034 12.3 33.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EOO02580.1 - 1.3 8.8 34.6 2 8.2 24.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.8 EOO02580.1 - 4 5.4 26.4 4.9 5.1 18.3 1.0 1 0 0 1 1 1 0 Utp14 protein Complex1_LYR PF05347.10 EOO02581.1 - 3.1e-11 42.9 2.7 4.2e-11 42.4 1.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EOO02581.1 - 9.9e-09 35.2 1.5 1.4e-08 34.8 1.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HSF_DNA-bind PF00447.12 EOO02582.1 - 3.8e-37 126.6 0.1 9.5e-37 125.3 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EOO02582.1 - 5.7e-21 74.6 0.3 9.9e-21 73.8 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF1635 PF07795.6 EOO02582.1 - 0.036 13.4 0.5 0.061 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF904 PF06005.7 EOO02582.1 - 0.06 13.6 3.0 0.12 12.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CENP-H PF05837.7 EOO02582.1 - 0.086 13.0 4.3 0.16 12.1 3.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 EOO02582.1 - 0.11 12.8 1.6 0.24 11.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EOO02582.1 - 0.48 9.9 3.2 0.73 9.3 2.2 1.2 1 0 0 1 1 1 0 IncA protein Sec23_trunk PF04811.10 EOO02583.1 - 2.2e-70 236.8 0.0 3.3e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EOO02583.1 - 3e-25 87.6 0.1 8.4e-24 82.9 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EOO02583.1 - 1.5e-17 63.8 0.0 3.3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EOO02583.1 - 2.6e-10 39.8 0.0 5.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 EOO02583.1 - 0.2 11.6 0.7 0.47 10.4 0.5 1.5 1 0 0 1 1 1 0 Testis-expressed 12 DnaJ PF00226.26 EOO02585.1 - 9.3e-24 82.9 3.8 1.2e-23 82.5 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EOO02585.1 - 9.4e-10 38.3 4.8 9.4e-10 38.3 3.3 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EOO02585.1 - 1.3e-09 37.9 8.3 4.3e-09 36.2 1.7 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EOO02585.1 - 2.7e-07 30.6 8.4 0.00031 20.7 1.8 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EOO02585.1 - 8.5e-06 25.8 6.0 0.047 14.0 0.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO02585.1 - 2.2e-05 24.4 2.1 0.18 12.2 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EOO02585.1 - 0.00019 21.2 8.0 0.063 13.2 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2387 PF09526.5 EOO02585.1 - 0.0062 16.4 2.1 0.022 14.6 1.4 1.9 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Lact-deh-memb PF09330.6 EOO02585.1 - 0.083 12.2 2.4 0.13 11.6 1.7 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Rep_N PF08724.5 EOO02585.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Rep protein catalytic domain like RRM_1 PF00076.17 EOO02586.1 - 5.1e-33 112.5 0.0 6.2e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02586.1 - 8.8e-29 99.2 0.0 1.2e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02586.1 - 7e-13 48.2 0.0 2.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 EOO02586.1 - 0.0017 17.8 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RRM_3 PF08777.6 EOO02586.1 - 0.094 12.5 0.0 6.4 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Acetyltransf_7 PF13508.1 EOO02587.1 - 9e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO02587.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EOO02587.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EOO02587.1 - 0.0034 17.5 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.17 EOO02588.1 - 2.5e-20 71.8 0.1 1.1e-12 47.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02588.1 - 2.6e-15 56.1 0.0 3.1e-09 36.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02588.1 - 1.4e-06 27.9 0.7 0.013 15.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EOO02588.1 - 0.71 9.7 12.1 0.51 10.1 5.8 2.6 2 1 1 3 3 3 0 RNA binding motif Chitin_synth_1 PF01644.12 EOO02589.1 - 1.1e-80 269.1 0.3 1.7e-80 268.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EOO02589.1 - 2.1e-32 110.6 0.0 3.9e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EOO02589.1 - 1.2e-23 83.3 0.2 9e-18 63.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EOO02589.1 - 4.2e-08 33.1 5.8 4.2e-08 33.1 4.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EOO02589.1 - 3e-07 30.4 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Prominin PF05478.6 EOO02589.1 - 0.021 12.4 0.0 0.036 11.6 0.0 1.4 1 0 0 1 1 1 0 Prominin FHA PF00498.21 EOO02590.1 - 4.7e-10 39.4 0.2 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 FHA domain Peptidase_S10 PF00450.17 EOO02591.1 - 2.5e-90 303.6 0.0 3.4e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HIF-1 PF11413.3 EOO02591.1 - 0.086 12.0 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 zf-CCCH PF00642.19 EOO02592.1 - 0.0015 18.1 1.3 0.0025 17.4 0.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EOO02592.1 - 0.012 15.5 3.0 0.019 14.9 2.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Glutaredoxin PF00462.19 EOO02593.1 - 2.4e-15 56.2 0.0 4.6e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Synthase_beta PF11421.3 EOO02593.1 - 0.69 10.6 6.5 7.8 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Rad52_Rad22 PF04098.10 EOO02594.1 - 7.3e-62 207.6 0.0 1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein GST_N_2 PF13409.1 EOO02595.1 - 1.9e-13 50.1 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EOO02595.1 - 3.8e-12 46.2 0.0 6.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EOO02595.1 - 3.5e-08 33.4 0.0 6.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EOO02595.1 - 5.9e-07 29.2 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EOO02595.1 - 7.9e-06 25.7 0.0 3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EOO02595.1 - 0.011 16.1 0.1 0.019 15.4 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PPTA PF01239.17 EOO02595.1 - 0.069 12.5 0.2 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat PRELI PF04707.9 EOO02596.1 - 2.4e-21 75.9 0.0 1.2e-17 63.9 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family HEAT PF02985.17 EOO02598.1 - 6.9e-07 28.8 0.0 0.035 14.1 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Pkinase_Tyr PF07714.12 EOO02598.1 - 5.9e-05 22.2 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02598.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.2 EOO02598.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EOO02598.1 - 0.1 12.8 0.0 3.3 8.0 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats Lsm_interact PF05391.6 EOO02598.1 - 0.44 10.0 0.1 0.44 10.0 0.0 2.6 3 0 0 3 3 3 0 Lsm interaction motif Aconitase PF00330.15 EOO02599.1 - 4.8e-152 506.6 0.0 1.4e-151 505.1 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EOO02599.1 - 7.3e-38 129.6 0.0 1.2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Actin PF00022.14 EOO02600.1 - 6.1e-133 443.0 0.0 6.9e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Actin Transthyretin PF00576.16 EOO02601.1 - 7e-28 96.7 0.8 7.6e-17 61.2 0.3 2.1 1 1 0 2 2 2 2 HIUase/Transthyretin family tRNA-synt_1b PF00579.20 EOO02602.1 - 6.8e-22 77.9 0.5 1.2e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.14 EOO02603.1 - 3e-17 62.8 0.0 3.9e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ArsA_ATPase PF02374.10 EOO02604.1 - 1.7e-113 378.7 0.0 1.9e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EOO02604.1 - 1.6e-16 60.3 0.2 6.5e-16 58.3 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EOO02604.1 - 1.3e-08 34.8 0.0 7.3e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EOO02604.1 - 4.3e-06 26.1 0.0 8.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EOO02604.1 - 3.2e-05 23.4 0.4 0.0012 18.3 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EOO02604.1 - 0.0057 16.0 0.1 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02604.1 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain YhjQ PF06564.7 EOO02604.1 - 0.022 14.1 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 YhjQ protein IstB_IS21 PF01695.12 EOO02604.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 EOO02604.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EOO02604.1 - 0.074 11.8 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3763 PF12592.3 EOO02604.1 - 0.076 12.6 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) AAA_18 PF13238.1 EOO02604.1 - 0.11 12.8 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sec1 PF00995.18 EOO02605.1 - 2.9e-152 508.2 0.0 3.4e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2985 PF11204.3 EOO02605.1 - 0.12 12.1 0.0 9.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) G_glu_transpept PF01019.16 EOO02606.1 - 2.5e-149 498.0 0.0 2.9e-149 497.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GHMP_kinases_N PF00288.21 EOO02608.1 - 1.7e-12 47.2 0.0 3.9e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EOO02608.1 - 2.9e-05 24.1 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal ZZ PF00569.12 EOO02609.1 - 3.8e-20 71.1 60.1 2.1e-06 27.1 6.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type WD40 PF00400.27 EOO02610.1 - 1.4e-47 157.9 19.5 1.3e-11 43.8 0.0 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EOO02610.1 - 2.6e-05 22.5 4.4 0.28 9.2 0.1 4.6 3 1 1 5 5 5 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EOO02610.1 - 0.021 13.0 0.0 0.049 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EOO02610.1 - 0.028 13.2 0.6 1.8 7.2 0.1 3.1 1 1 1 2 2 2 0 Nup133 N terminal like HPS3_N PF14761.1 EOO02610.1 - 0.035 13.5 0.0 0.38 10.1 0.0 2.2 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Btz PF09405.5 EOO02611.1 - 1.5e-27 96.1 2.2 4.3e-27 94.7 1.5 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding TFIIF_alpha PF05793.7 EOO02611.1 - 4.7 5.4 7.5 6 5.1 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Flavoprotein PF02441.14 EOO02613.1 - 3.1e-42 143.2 0.1 4.1e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein IFRD PF05004.8 EOO02614.1 - 1.8e-23 83.1 0.0 2.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EOO02614.1 - 0.019 15.2 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats HET PF06985.6 EOO02615.1 - 1.6e-27 96.4 0.7 3.2e-27 95.4 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UPF0052 PF01933.13 EOO02616.1 - 9.5e-49 166.3 0.0 1.6e-48 165.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Cut8_C PF08559.5 EOO02617.1 - 7.2e-48 162.0 0.0 9.6e-48 161.6 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EOO02617.1 - 2.9e-16 58.9 0.6 6.4e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EOO02617.1 - 2.3e-08 33.9 1.8 4.7e-08 32.9 1.2 1.6 1 0 0 1 1 1 1 Cut8 proteasome-binding domain AP_endonuc_2 PF01261.19 EOO02617.1 - 0.033 13.4 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Asp PF00026.18 EOO02618.1 - 3.6e-59 200.5 3.0 4.7e-59 200.2 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO02618.1 - 1.2e-07 31.8 0.0 8.5e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO02618.1 - 8.4e-07 29.4 4.4 0.0031 17.9 0.1 3.3 3 1 0 3 3 3 2 Aspartyl protease RF-1 PF00472.15 EOO02619.1 - 2.2e-33 114.4 2.0 4.2e-33 113.5 1.4 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EOO02619.1 - 1.4e-26 92.4 0.0 8.9e-26 89.8 0.0 2.2 2 0 0 2 2 2 1 PCRF domain S_100 PF01023.14 EOO02619.1 - 0.15 11.4 0.5 0.73 9.1 0.0 2.1 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain FlgN PF05130.7 EOO02619.1 - 0.22 11.7 4.8 0.61 10.3 3.4 1.7 1 0 0 1 1 1 0 FlgN protein DUF3602 PF12223.3 EOO02620.1 - 4.4e-18 65.4 15.3 1e-14 54.6 2.2 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) TPR_11 PF13414.1 EOO02621.1 - 6.6e-55 182.6 20.0 4e-14 52.0 0.1 6.6 4 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EOO02621.1 - 9.4e-46 151.6 26.7 1.1e-06 27.9 0.0 11.2 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EOO02621.1 - 4.7e-42 138.5 24.4 9.7e-06 25.1 0.1 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 EOO02621.1 - 2.4e-29 101.0 21.8 2.8e-09 36.7 0.0 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EOO02621.1 - 3.9e-29 100.6 5.9 4.2e-07 30.4 0.1 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EOO02621.1 - 5.1e-23 79.3 7.1 0.0006 19.8 0.0 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EOO02621.1 - 5.3e-15 54.5 13.4 0.036 14.7 0.6 9.3 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EOO02621.1 - 5.7e-15 53.8 19.9 0.022 14.5 0.0 9.9 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EOO02621.1 - 6.9e-15 54.6 7.2 9.5e-05 22.1 0.1 6.0 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EOO02621.1 - 1e-14 53.0 25.0 0.0017 17.9 0.0 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EOO02621.1 - 1.4e-13 50.9 19.9 2.2e-06 27.9 1.2 6.3 3 2 3 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EOO02621.1 - 9.6e-10 38.4 16.2 0.0022 18.1 0.3 5.5 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EOO02621.1 - 2.4e-07 29.8 2.8 0.29 10.4 0.0 5.9 6 0 0 6 6 6 1 SHNi-TPR TPR_15 PF13429.1 EOO02621.1 - 2.9e-07 29.8 5.5 1.2 8.0 0.1 5.1 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 EOO02621.1 - 0.00018 21.3 11.3 1.6 8.7 0.5 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF3856 PF12968.2 EOO02621.1 - 0.00044 20.0 8.2 3.1 7.6 0.1 6.0 6 1 1 7 7 7 2 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EOO02621.1 - 0.0073 16.7 23.2 4.7 7.9 0.4 8.4 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 EOO02621.1 - 0.028 14.5 8.6 0.43 10.7 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc5 PF12862.2 EOO02621.1 - 0.12 12.2 6.1 7.7 6.4 0.0 4.8 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 MAS20 PF02064.10 EOO02621.1 - 0.2 11.5 11.3 3.2 7.6 0.0 4.3 4 1 0 4 4 3 0 MAS20 protein import receptor Sel1 PF08238.7 EOO02621.1 - 0.86 10.3 8.7 1.8 9.3 0.2 4.1 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.7 EOO02621.1 - 1.3 8.8 24.2 3.6 7.5 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 EOO02621.1 - 5 7.0 16.3 20 5.1 0.0 6.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain DWNN PF08783.6 EOO02622.1 - 1.6e-29 101.6 0.0 3.1e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 EOO02622.1 - 7.8e-05 22.4 2.1 0.00015 21.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EOO02622.1 - 0.00025 20.4 3.7 0.00025 20.4 2.5 2.2 2 0 0 2 2 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EOO02622.1 - 0.00058 19.5 0.3 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle MIP-T3 PF10243.4 EOO02622.1 - 0.0077 14.7 23.9 0.099 11.1 3.6 2.1 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 SOBP PF15279.1 EOO02622.1 - 0.056 13.8 32.0 0.11 12.8 14.9 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein zf-Nse PF11789.3 EOO02622.1 - 0.06 12.8 3.5 0.16 11.5 2.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EOO02622.1 - 1 9.4 14.4 0.15 12.1 5.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO02622.1 - 1.5 8.5 7.8 3.3 7.4 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02622.1 - 3.2 7.5 11.7 0.59 9.9 4.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EOO02622.1 - 5.4 6.9 9.1 17 5.3 6.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EOO02622.1 - 7.5 6.3 9.2 1.4 8.6 2.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNARE PF05739.14 EOO02623.1 - 2.8e-13 49.3 4.8 4.2e-13 48.7 2.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EOO02623.1 - 6.2e-10 39.1 10.4 8.4e-10 38.7 2.6 2.4 2 0 0 2 2 2 1 Syntaxin Tannase PF07519.6 EOO02623.1 - 0.029 13.0 0.3 0.031 13.0 0.2 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Sipho_Gp157 PF05565.6 EOO02623.1 - 0.039 13.5 0.3 0.088 12.3 0.2 1.6 1 1 0 1 1 1 0 Siphovirus Gp157 Syntaxin_2 PF14523.1 EOO02623.1 - 0.12 12.3 11.0 0.21 11.6 2.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Allexi_40kDa PF05549.6 EOO02623.1 - 0.49 9.6 3.7 0.67 9.1 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.6 EOO02623.1 - 0.5 7.8 2.8 2.9 5.3 0.1 2.1 2 0 0 2 2 2 0 Prominin CENP-F_leu_zip PF10473.4 EOO02623.1 - 0.81 9.5 9.4 0.58 10.0 0.7 3.4 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 EOO02623.1 - 2.1 8.4 8.6 12 6.0 0.4 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CCDC155 PF14662.1 EOO02623.1 - 4.9 6.6 11.6 0.17 11.4 1.3 2.4 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 DUF3552 PF12072.3 EOO02623.1 - 8.6 5.5 13.9 0.083 12.0 0.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 EOO02623.1 - 8.8 5.1 13.0 0.21 10.5 3.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1640 PF07798.6 EOO02624.1 - 1.5e-56 191.2 5.5 1.6e-56 191.1 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Lzipper-MIP1 PF14389.1 EOO02624.1 - 0.0028 17.7 3.8 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Syntaxin PF00804.20 EOO02624.1 - 0.013 15.6 4.7 0.013 15.6 3.3 2.2 1 1 1 2 2 2 0 Syntaxin DUF1383 PF07134.6 EOO02624.1 - 0.079 11.8 1.0 0.11 11.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1383) cwf21 PF08312.7 EOO02624.1 - 0.1 12.4 2.6 0.42 10.5 1.8 2.2 1 1 0 1 1 1 0 cwf21 domain FTA4 PF13093.1 EOO02624.1 - 0.66 9.3 7.4 1 8.7 5.2 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 THOC7 PF05615.8 EOO02624.1 - 1.8 8.8 8.8 4.1 7.6 6.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Lge1 PF11488.3 EOO02624.1 - 2.2 8.5 6.1 1.1e+02 3.1 4.2 2.4 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 D-ser_dehydrat PF14031.1 EOO02625.1 - 1.3e-21 76.5 0.0 5.5e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EOO02625.1 - 5.2e-11 42.5 0.4 9.1e-11 41.7 0.3 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Bacillus_HBL PF05791.6 EOO02626.1 - 0.0089 15.4 2.0 0.013 14.8 1.4 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF489 PF04356.7 EOO02626.1 - 0.0091 15.6 1.2 0.012 15.2 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF489) ERM PF00769.14 EOO02626.1 - 0.053 13.0 19.2 0.072 12.6 13.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family B-block_TFIIIC PF04182.7 EOO02626.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Baculo_PEP_C PF04513.7 EOO02626.1 - 0.11 12.3 0.1 0.3 10.9 0.0 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.14 EOO02626.1 - 0.19 12.1 4.0 0.38 11.1 2.6 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein V_ATPase_I PF01496.14 EOO02626.1 - 0.61 7.8 4.7 0.69 7.7 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.1 EOO02626.1 - 0.65 9.9 8.5 1.7 8.6 1.1 3.0 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 WXG100 PF06013.7 EOO02626.1 - 2.2 8.3 5.6 21 5.1 0.1 3.0 1 1 3 4 4 4 0 Proteins of 100 residues with WXG Mgr1 PF08602.5 EOO02626.1 - 2.2 7.2 5.0 3.4 6.5 3.5 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Fib_alpha PF08702.5 EOO02626.1 - 3.2 7.8 7.2 9.5 6.3 4.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EOO02626.1 - 9.4 5.7 8.1 13 5.3 0.7 2.8 1 1 1 2 2 2 0 Septum formation initiator Ribonuc_L-PSP PF01042.16 EOO02627.1 - 2.4e-39 133.8 0.1 2.6e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DPPIV_N PF00930.16 EOO02628.1 - 3.6e-105 351.4 0.8 4.8e-105 351.0 0.6 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EOO02628.1 - 3.2e-52 176.8 1.8 7e-52 175.7 1.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EOO02628.1 - 1.2e-10 41.2 0.1 5.5e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EOO02628.1 - 8e-08 32.0 1.1 2.1e-05 24.0 0.4 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EOO02628.1 - 9.3e-08 32.2 0.1 1.4e-06 28.3 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EOO02628.1 - 0.0078 15.5 0.2 0.077 12.2 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF3357 PF11837.3 EOO02628.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Abhydrolase_3 PF07859.8 EOO02628.1 - 0.1 12.1 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold KR PF08659.5 EOO02629.1 - 4.9e-29 101.2 0.2 1.7e-28 99.5 0.1 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EOO02629.1 - 2.3e-20 73.1 1.3 1e-19 71.0 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EOO02629.1 - 2.1e-19 69.8 0.0 8.2e-19 67.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EOO02629.1 - 2.6e-19 69.0 1.7 2e-18 66.1 0.1 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EOO02629.1 - 1.6e-13 50.7 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EOO02629.1 - 3.9e-13 50.3 0.0 5.1e-11 43.5 0.0 3.5 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EOO02629.1 - 5.6e-10 39.5 0.0 8e-09 35.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02629.1 - 1.3e-07 31.3 0.0 3.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO02629.1 - 1.3e-07 32.1 0.0 9.5e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EOO02629.1 - 2.1e-07 31.1 0.5 6e-07 29.6 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EOO02629.1 - 1.2e-06 27.8 0.0 2.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 EOO02629.1 - 8.9e-05 22.2 0.2 0.0002 21.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NodS PF05401.6 EOO02629.1 - 0.019 14.3 0.0 0.04 13.2 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Glycos_transf_N PF04413.11 EOO02629.1 - 0.02 14.0 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) MTS PF05175.9 EOO02629.1 - 0.052 12.9 0.1 0.32 10.3 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EOO02629.1 - 0.092 12.1 0.0 0.29 10.5 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase Glyco_hydro_47 PF01532.15 EOO02630.1 - 6.7e-71 239.2 0.0 8.1e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4407 PF14362.1 EOO02631.1 - 0.13 11.1 12.9 0.23 10.3 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pilt PF15453.1 EOO02631.1 - 0.45 10.1 15.5 0.55 9.8 10.8 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Dynactin_p62 PF05502.8 EOO02631.1 - 2.6 6.7 12.3 3.3 6.3 8.5 1.2 1 0 0 1 1 1 0 Dynactin p62 family Hex_IIIa PF02455.11 EOO02631.1 - 7 5.2 15.4 8.5 4.9 10.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Gln-synt_C PF00120.19 EOO02632.1 - 6.7e-63 212.2 0.0 8e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EOO02632.1 - 2.3e-20 71.9 0.0 3.5e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain KH_3 PF13014.1 EOO02632.1 - 0.089 12.4 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 KH domain Clathrin PF00637.15 EOO02633.1 - 2.5e-206 675.5 29.0 4.5e-33 113.8 1.3 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EOO02633.1 - 2.1e-31 106.0 4.5 0.0011 19.1 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EOO02633.1 - 2.6e-31 107.2 0.1 1.1e-30 105.2 0.0 2.2 1 0 0 1 1 1 1 Clathrin-H-link TPR_12 PF13424.1 EOO02633.1 - 2.2e-06 27.4 2.3 2.1 8.3 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EOO02633.1 - 2.7e-05 23.6 6.1 0.8 9.6 0.1 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO02633.1 - 0.021 14.4 4.1 14 5.4 0.3 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2191 PF09957.4 EOO02633.1 - 0.041 13.6 0.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_2 PF07719.12 EOO02633.1 - 0.28 11.1 8.0 43 4.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO02633.1 - 0.43 11.3 14.1 97 4.0 0.0 8.1 10 1 1 11 11 11 0 Tetratricopeptide repeat MFS_1 PF07690.11 EOO02634.1 - 1.2e-33 116.3 27.9 1.2e-33 116.3 19.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 EOO02635.1 - 1.6e-42 145.0 0.0 2.1e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_3 PF07859.8 EOO02637.1 - 3.2e-63 213.1 0.0 4.2e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EOO02637.1 - 2.2e-08 33.2 0.1 4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EOO02637.1 - 1.8e-07 30.6 0.0 3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EOO02637.1 - 3.1e-05 22.8 0.0 5.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EOO02637.1 - 0.00026 20.7 0.0 0.00056 19.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EOO02637.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DCR PF14047.1 EOO02638.1 - 0.00066 19.9 13.4 1.7 9.0 0.3 4.2 4 0 0 4 4 4 4 Dppa2/4 conserved region DUF3551 PF12071.3 EOO02638.1 - 0.01 15.3 1.7 0.11 12.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3551) MSG PF02349.10 EOO02638.1 - 0.038 13.9 1.6 4.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Major surface glycoprotein TPM PF04536.9 EOO02638.1 - 0.13 12.0 0.1 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase FinO_N PF12602.3 EOO02638.1 - 5.4 7.3 7.2 17 5.7 0.3 2.6 2 1 0 2 2 2 0 Fertility inhibition protein N terminal AA_permease_2 PF13520.1 EOO02640.1 - 2.8e-23 82.1 40.2 7.6e-20 70.8 21.3 2.0 1 1 1 2 2 2 2 Amino acid permease HC2 PF07382.6 EOO02641.1 - 0.013 15.4 40.7 0.017 14.9 28.2 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 RNA_pol_Rpb1_2 PF00623.15 EOO02641.1 - 8.8 6.2 15.9 0.82 9.6 6.5 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 2 V-SNARE PF05008.10 EOO02642.1 - 0.95 9.6 5.3 2.2 8.4 3.7 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus YbjQ_1 PF01906.12 EOO02643.1 - 4.2e-29 101.0 0.2 4.9e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding YobH PF13996.1 EOO02643.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 YobH-like protein FMN_dh PF01070.13 EOO02645.1 - 2e-87 293.3 0.0 1e-84 284.4 0.0 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_M19 PF01244.16 EOO02645.1 - 0.00027 20.0 0.0 0.00069 18.6 0.0 1.6 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) DHO_dh PF01180.16 EOO02645.1 - 0.0013 17.7 0.1 0.0063 15.5 0.0 2.1 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EOO02645.1 - 0.01 15.0 0.4 0.74 9.0 0.0 2.7 1 1 1 2 2 2 0 Histidine biosynthesis protein IMPDH PF00478.20 EOO02645.1 - 0.028 13.3 0.1 0.066 12.0 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EOO02645.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Glu_synthase PF01645.12 EOO02645.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Sugar_tr PF00083.19 EOO02646.1 - 1.7e-68 231.2 25.1 3.9e-55 187.2 9.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1593 PF07632.6 EOO02647.1 - 2.2e-99 331.9 0.1 3e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EOO02647.1 - 0.004 15.5 0.1 0.006 14.9 0.1 1.1 1 0 0 1 1 1 1 REJ domain Amidase PF01425.16 EOO02648.1 - 1.4e-15 57.0 0.0 1.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EOO02649.1 - 5.8e-25 87.7 34.5 2.5e-24 85.6 23.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EOO02649.1 - 1.3 9.1 8.6 0.16 12.0 0.4 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) adh_short PF00106.20 EOO02650.1 - 3.5e-21 75.8 0.2 6.5e-21 74.9 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO02650.1 - 3.3e-13 49.6 0.0 4.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO02650.1 - 8.6e-07 28.9 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EOO02650.1 - 0.0041 16.0 0.1 0.011 14.6 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EOO02650.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EOO02650.1 - 0.044 12.4 0.3 0.12 11.0 0.2 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EOO02650.1 - 0.12 11.2 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phosphoesterase PF04185.9 EOO02651.1 - 2.3e-61 208.1 0.9 3.1e-61 207.6 0.6 1.2 1 0 0 1 1 1 1 Phosphoesterase family Hydantoinase_A PF01968.13 EOO02652.1 - 2.9e-80 269.4 8.4 4.3e-79 265.6 2.3 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EOO02652.1 - 2.3e-51 174.6 0.0 9.8e-36 123.0 0.0 2.9 2 1 1 3 3 3 2 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EOO02652.1 - 3.2e-46 157.0 0.4 1.5e-43 148.3 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EOO02652.1 - 0.012 14.8 0.8 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family C2 PF00168.25 EOO02653.1 - 2.2e-14 53.0 0.1 7.8e-11 41.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EOO02653.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Dioxygenase_C PF00775.16 EOO02654.1 - 1.3e-44 151.5 0.0 1.8e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EOO02654.1 - 4.3e-12 45.8 0.0 7.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Cna_B PF05738.8 EOO02654.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 EOO02654.1 - 0.011 15.7 0.0 0.046 13.7 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EOO02654.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Trep_Strep PF09605.5 EOO02655.1 - 2.7 7.6 9.0 0.068 12.8 0.7 2.1 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Aldo_ket_red PF00248.16 EOO02657.1 - 1.6e-13 50.1 0.0 2.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.19 EOO02658.1 - 4.3e-08 33.0 0.0 7.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EOO02658.1 - 1.5e-06 28.4 0.0 2.3e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EOO02658.1 - 0.00026 20.9 0.1 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO02658.1 - 0.051 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HATPase_c PF02518.21 EOO02659.1 - 3.1e-30 104.1 0.0 8.3e-30 102.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EOO02659.1 - 6.3e-28 97.0 0.3 1.2e-27 96.1 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EOO02659.1 - 2.2e-13 50.0 0.0 5.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EOO02659.1 - 0.00011 22.2 2.2 0.087 13.0 0.0 3.5 3 0 0 3 3 3 2 HAMP domain GRP PF07172.6 EOO02660.1 - 0.12 12.8 0.1 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family AIM24 PF01987.12 EOO02661.1 - 8.2e-51 172.5 0.1 9.7e-51 172.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 IDO PF01231.13 EOO02662.1 - 8e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RRP7 PF12923.2 EOO02663.1 - 4.8e-38 130.1 14.4 4.8e-38 130.1 10.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) INO80_Ies4 PF08193.6 EOO02664.1 - 1.5e-65 221.2 20.7 1.7e-65 221.0 14.4 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 FUSC_2 PF13515.1 EOO02665.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like adh_short PF00106.20 EOO02666.1 - 1.3e-31 109.7 0.2 2e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO02666.1 - 1.2e-27 97.2 0.0 1.8e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO02666.1 - 1.4e-14 54.1 0.1 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO02666.1 - 0.055 12.8 0.1 0.14 11.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.1 EOO02666.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain ORMDL PF04061.9 EOO02667.1 - 2.5e-61 205.1 4.2 3e-61 204.9 2.9 1.0 1 0 0 1 1 1 1 ORMDL family Pkinase PF00069.20 EOO02668.1 - 3e-58 197.0 0.0 3.5e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02668.1 - 1.1e-36 126.2 0.0 1.7e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02668.1 - 1.6e-05 24.0 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like A_deaminase PF00962.17 EOO02669.1 - 7.7e-41 140.0 0.0 3.2e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase Aldo_ket_red PF00248.16 EOO02670.1 - 6.5e-11 41.5 0.0 9e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MOSC PF03473.12 EOO02671.1 - 1.5e-09 37.4 0.0 3.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain NAD_binding_1 PF00175.16 EOO02671.1 - 4.7e-09 36.7 0.3 2.8e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2 PF00111.22 EOO02671.1 - 0.00035 20.2 0.1 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.19 EOO02671.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GTP_EFTU_D2 PF03144.20 EOO02671.1 - 0.014 15.5 0.1 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 2 HTH_32 PF13565.1 EOO02671.1 - 0.077 13.8 0.8 0.73 10.6 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain zf-CCHC_4 PF14392.1 EOO02673.1 - 0.016 14.8 25.8 0.032 13.8 0.3 4.4 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC PF00098.18 EOO02673.1 - 0.34 10.9 35.4 0.092 12.7 3.3 5.2 5 0 0 5 5 5 0 Zinc knuckle API5 PF05918.6 EOO02673.1 - 3 6.2 6.2 4.7 5.5 4.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pex24p PF06398.6 EOO02674.1 - 7.6e-98 327.6 0.0 8.9e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EOO02674.1 - 0.0064 14.4 0.4 0.011 13.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) GST_C_3 PF14497.1 EOO02675.1 - 1.3e-05 25.5 0.1 1.8e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EOO02675.1 - 0.00033 20.4 1.2 0.00069 19.4 0.8 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 EOO02675.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) PRP1_N PF06424.7 EOO02676.1 - 8.3e-45 152.3 8.1 4.6e-27 94.9 1.1 2.6 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EOO02676.1 - 3.2e-30 101.8 32.4 0.0012 19.2 0.1 14.2 6 5 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.1 EOO02676.1 - 1.6e-28 98.8 10.5 4.5e-06 26.8 0.1 9.0 7 2 3 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EOO02676.1 - 2.5e-24 85.3 16.1 0.00047 20.7 0.4 9.0 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EOO02676.1 - 1.4e-14 53.4 7.0 0.025 14.2 0.1 8.3 5 4 3 9 9 9 4 TPR repeat TPR_2 PF07719.12 EOO02676.1 - 2.2e-14 52.1 7.4 0.52 10.3 0.0 10.2 10 1 1 11 11 10 3 Tetratricopeptide repeat NARP1 PF12569.3 EOO02676.1 - 2.2e-10 39.9 0.8 0.012 14.3 0.0 5.8 4 1 2 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 EOO02676.1 - 4.4e-09 35.8 19.4 0.0043 16.1 0.6 6.5 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EOO02676.1 - 1.9e-08 33.8 2.3 1 9.6 0.0 8.7 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EOO02676.1 - 1.1e-06 28.3 5.8 0.0036 17.1 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO02676.1 - 1.3e-06 27.7 0.0 1 9.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EOO02676.1 - 6e-05 22.0 0.2 6e-05 22.0 0.1 4.6 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference TPR_21 PF09976.4 EOO02676.1 - 0.00044 20.2 6.6 0.039 13.8 0.4 4.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EOO02676.1 - 0.00054 19.5 0.3 2.6 8.0 0.1 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF3808 PF10300.4 EOO02676.1 - 0.031 12.8 0.5 1.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EOO02676.1 - 0.033 14.1 11.4 3.9 7.4 0.0 6.9 7 2 1 9 9 8 0 Tetratricopeptide repeat FAT PF02259.18 EOO02676.1 - 0.045 12.7 3.7 11 4.9 0.0 3.4 1 1 1 3 3 3 0 FAT domain TPR_6 PF13174.1 EOO02676.1 - 0.41 11.2 9.0 12 6.6 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat ChAPs PF09295.5 EOO02676.1 - 0.46 9.1 2.1 1.1 7.9 0.1 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Maf1 PF09174.5 EOO02677.1 - 5.3e-62 208.8 0.0 7.6e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF3052 PF11253.3 EOO02677.1 - 0.056 13.0 1.8 0.12 11.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) HAUS6_N PF14661.1 EOO02677.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PC4 PF02229.11 EOO02678.1 - 2.2e-21 74.8 0.1 3.6e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.1 EOO02678.1 - 0.84 9.6 7.6 0.08 12.9 1.1 1.9 1 1 0 2 2 2 0 YqfQ-like protein TUSC2 PF15000.1 EOO02678.1 - 9 6.3 8.2 3.9 7.5 0.5 2.7 2 1 1 3 3 3 0 Tumour suppressor candidate 2 polyprenyl_synt PF00348.12 EOO02679.1 - 1.2e-59 201.2 0.0 1.5e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1279 PF06916.8 EOO02680.1 - 3.1e-12 46.6 0.0 3.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MFS_1 PF07690.11 EOO02681.1 - 2.3e-34 118.6 35.1 2.8e-34 118.3 24.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Syndecan PF01034.15 EOO02681.1 - 0.0052 16.4 0.9 0.026 14.1 0.0 2.6 2 0 0 2 2 2 1 Syndecan domain PALP PF00291.20 EOO02682.1 - 6.5e-38 130.6 0.7 7.9e-38 130.4 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scytalone_dh PF02982.9 EOO02683.1 - 8.4e-62 207.4 0.4 1e-61 207.1 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EOO02683.1 - 7.1e-05 22.7 0.7 8.9e-05 22.4 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2555 PF10742.4 EOO02683.1 - 0.039 13.5 0.3 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) PP2C PF00481.16 EOO02684.1 - 4.1e-82 275.4 0.0 6.1e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EOO02684.1 - 0.0013 18.1 0.0 0.0038 16.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C MARVEL PF01284.18 EOO02685.1 - 1.1e-27 96.6 12.0 1.3e-27 96.3 8.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.6 EOO02685.1 - 0.055 13.3 5.4 1.2 9.0 2.0 2.8 2 1 0 2 2 2 0 M penetrans paralogue family 26 ADIP PF11559.3 EOO02686.1 - 1.7e-38 131.9 9.0 1.7e-38 131.9 6.2 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 EOO02686.1 - 0.00073 19.1 6.2 0.00073 19.1 4.3 3.1 3 0 0 3 3 3 1 IncA protein Spc7 PF08317.6 EOO02686.1 - 0.28 9.7 5.8 0.91 8.1 4.0 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 EOO02686.1 - 0.55 9.9 7.8 8.4 6.1 3.2 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 EOO02686.1 - 0.8 9.4 11.4 7.4 6.3 3.6 3.5 3 1 0 3 3 3 0 Laminin Domain II PhoU PF01895.14 EOO02686.1 - 2.6 8.5 8.3 20 5.7 0.1 4.1 4 1 1 5 5 5 0 PhoU domain MIF4G_like_2 PF09090.6 EOO02686.1 - 6.3 5.9 8.2 7.2 5.7 0.9 2.5 3 0 0 3 3 3 0 MIF4G like CLTH PF10607.4 EOO02687.1 - 1.2e-36 125.6 0.4 2.4e-36 124.6 0.3 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EOO02687.1 - 6.6e-09 35.9 0.1 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EOO02687.1 - 2e-06 27.3 1.0 7.6e-06 25.5 0.0 2.4 3 0 0 3 3 3 1 LisH DUF387 PF04079.11 EOO02687.1 - 0.0013 18.1 0.0 0.0039 16.5 0.0 1.8 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) PAM2 PF07145.10 EOO02688.1 - 0.011 15.1 0.1 0.034 13.6 0.1 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Ndc1_Nup PF09531.5 EOO02688.1 - 5.4 5.2 5.5 2.4 6.5 1.1 2.0 1 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DAO PF01266.19 EOO02690.1 - 3.1e-50 171.1 0.6 5.5e-50 170.2 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO02690.1 - 0.00032 20.8 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO02690.1 - 0.0006 19.7 0.2 0.0014 18.5 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EOO02690.1 - 0.0014 18.5 0.0 0.0071 16.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO02690.1 - 0.0029 16.5 0.5 0.021 13.6 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EOO02690.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EOO02690.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Oxysterol_BP PF01237.13 EOO02691.1 - 1.9e-107 358.8 0.0 2.3e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein ketoacyl-synt PF00109.21 EOO02692.1 - 9.7e-73 244.7 0.0 1.6e-72 244.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EOO02692.1 - 2.4e-49 168.3 0.0 8.5e-48 163.3 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 EOO02692.1 - 7.2e-43 147.4 0.0 1.9e-42 146.0 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EOO02692.1 - 2.2e-34 117.8 1.0 5.6e-34 116.5 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EOO02692.1 - 5.2e-23 81.0 3.6 1.9e-10 40.8 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EOO02692.1 - 2.5e-06 27.5 2.6 0.0034 17.3 0.0 3.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02692.1 - 9.4e-06 25.4 0.2 0.089 12.5 0.0 3.2 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EOO02692.1 - 0.0019 17.2 0.1 0.006 15.5 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_3 PF01596.12 EOO02696.1 - 1.5e-37 128.6 0.0 2.2e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EOO02696.1 - 2.2e-12 47.7 0.1 1.7e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EOO02696.1 - 1.2e-10 41.2 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EOO02696.1 - 4.1e-10 40.2 0.0 8e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02696.1 - 4.7e-10 39.2 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO02696.1 - 1.8e-06 28.0 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO02696.1 - 2.9e-05 24.4 0.1 0.00028 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO02696.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EOO02696.1 - 0.0043 17.3 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO02696.1 - 0.0058 17.0 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO02696.1 - 0.019 13.9 0.0 0.045 12.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase GCD14 PF08704.5 EOO02696.1 - 0.02 14.3 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Usp PF00582.21 EOO02696.1 - 0.027 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Ubie_methyltran PF01209.13 EOO02696.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Response_reg PF00072.19 EOO02696.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain Apolipoprotein PF01442.13 EOO02697.1 - 0.00094 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EOO02697.1 - 0.0035 17.3 5.2 0.0046 16.9 3.6 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.9 EOO02697.1 - 0.043 13.7 3.2 0.052 13.4 2.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LUC7 PF03194.10 EOO02697.1 - 0.21 11.0 2.1 0.25 10.8 1.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Borrelia_P83 PF05262.6 EOO02697.1 - 0.24 9.6 9.6 0.3 9.3 6.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt_B PF00430.13 EOO02697.1 - 1.1 9.0 8.4 0.84 9.4 4.8 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF883 PF05957.8 EOO02697.1 - 2.4 8.5 5.8 2.8 8.4 1.9 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DNA_pol_E_B PF04042.11 EOO02698.1 - 1.1e-62 210.9 0.0 1.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Hydantoinase_B PF02538.9 EOO02699.1 - 3.4e-200 665.7 1.2 9.5e-194 644.4 0.0 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EOO02699.1 - 1.4e-95 319.7 0.7 3e-95 318.6 0.5 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO02699.1 - 5e-59 198.7 5.0 1.5e-58 197.1 0.3 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region SH2_2 PF14633.1 EOO02700.1 - 5.6e-83 277.3 0.1 5.6e-83 277.3 0.1 2.1 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EOO02700.1 - 3.7e-37 126.9 3.8 3.7e-37 126.9 2.6 3.9 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 EOO02700.1 - 4.3e-32 110.7 0.0 3e-31 108.0 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EOO02700.1 - 3.9e-29 100.8 0.0 1.1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EOO02700.1 - 4.6e-25 87.5 34.6 4.6e-25 87.5 24.0 6.7 6 1 1 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EOO02700.1 - 2.5e-19 69.4 2.5 4.1e-18 65.5 1.7 2.8 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 EOO02700.1 - 8.3e-07 29.0 0.3 2.6e-06 27.4 0.2 2.0 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EOO02700.1 - 2.4e-05 24.0 0.0 5.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EOO02700.1 - 0.0043 16.9 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif B12-binding PF02310.14 EOO02700.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DUF92 PF01940.11 EOO02701.1 - 5.1e-54 182.7 0.1 7.2e-49 165.9 0.0 2.1 1 1 1 2 2 2 2 Integral membrane protein DUF92 CTP_transf_1 PF01148.15 EOO02701.1 - 0.26 10.9 3.9 0.3 10.7 0.5 2.1 2 0 0 2 2 2 0 Cytidylyltransferase family MFS_1 PF07690.11 EOO02702.1 - 9e-33 113.4 26.8 1.4e-32 112.8 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ALMT PF11744.3 EOO02702.1 - 0.048 12.3 0.6 0.077 11.6 0.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter HAD_2 PF13419.1 EOO02703.1 - 3.3e-11 43.7 0.0 1e-07 32.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EOO02703.1 - 1.3e-07 31.1 0.2 2.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EOO02703.1 - 3.6e-05 24.2 0.1 0.0001 22.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EOO02703.1 - 0.0083 16.3 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EOO02704.1 - 0.0017 17.2 0.9 0.083 11.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain PNGaseA PF12222.3 EOO02705.1 - 2.8e-137 458.1 7.1 4.4e-132 440.9 5.3 2.1 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A NtA PF03146.10 EOO02705.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Agrin NtA domain APH PF01636.18 EOO02706.1 - 1.4e-09 38.0 1.4 0.00017 21.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EOO02706.1 - 2e-09 36.9 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EOO02706.1 - 1.2e-07 31.0 0.0 8.9e-07 28.1 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EOO02706.1 - 8.4e-07 28.3 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EOO02706.1 - 0.00028 20.2 0.0 0.0009 18.6 0.0 1.9 1 1 0 1 1 1 1 RIO1 family CDC14 PF08045.6 EOO02707.1 - 7.1e-94 313.7 0.0 8.2e-94 313.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Cu-oxidase_2 PF07731.9 EOO02708.1 - 2.9e-43 146.7 6.1 5.9e-38 129.4 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EOO02708.1 - 4.2e-42 142.5 5.5 2.4e-39 133.7 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EOO02708.1 - 5.2e-29 101.2 0.2 4.1e-27 95.0 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EOO02708.1 - 0.018 14.9 0.0 6.4 6.7 0.0 3.1 3 1 0 3 3 3 0 Cupredoxin-like domain Pkinase PF00069.20 EOO02709.1 - 1.6e-57 194.6 0.0 2.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02709.1 - 7.7e-22 77.5 0.4 1.4e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EOO02709.1 - 0.0033 17.1 0.0 0.03 14.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EOO02709.1 - 0.022 14.3 0.9 0.022 14.3 0.6 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 EOO02709.1 - 0.072 12.4 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 RIO1 family IBR PF01485.16 EOO02710.1 - 0.00016 21.4 12.6 0.00016 21.4 8.7 2.7 2 1 0 2 2 2 2 IBR domain eIF-5_eIF-2B PF01873.12 EOO02711.1 - 6.4e-45 151.8 0.1 9.9e-45 151.2 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EOO02711.1 - 0.049 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar MYT1 PF08474.6 EOO02711.1 - 0.13 11.6 1.4 1.4 8.3 0.3 2.3 1 1 1 2 2 2 0 Myelin transcription factor 1 CsbD PF05532.7 EOO02712.1 - 7.2e-18 64.0 25.9 4e-09 36.0 4.3 3.1 2 1 1 3 3 3 3 CsbD-like DUF2937 PF11157.3 EOO02712.1 - 0.064 12.5 1.3 0.11 11.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) AA_permease_2 PF13520.1 EOO02713.1 - 4.2e-49 167.2 35.3 5.6e-49 166.8 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO02713.1 - 3e-18 65.4 33.3 6.2e-18 64.3 23.1 1.4 1 1 0 1 1 1 1 Amino acid permease Clat_adaptor_s PF01217.15 EOO02714.1 - 3.5e-52 175.8 1.7 4.4e-52 175.5 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CMD PF02627.15 EOO02715.1 - 1e-08 34.8 0.0 3.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family BAR PF03114.13 EOO02716.1 - 3.8e-66 222.8 8.2 4.8e-66 222.5 5.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EOO02716.1 - 4.8e-15 54.6 0.3 9.5e-15 53.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EOO02716.1 - 1.3e-14 53.4 0.1 2.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EOO02716.1 - 2.5e-12 46.0 0.9 9.1e-12 44.2 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain Vps5 PF09325.5 EOO02716.1 - 0.56 9.4 9.4 6.7 5.8 3.3 2.2 2 0 0 2 2 2 0 Vps5 C terminal like DUF3986 PF13143.1 EOO02716.1 - 0.86 10.0 5.1 2.8 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) TMPIT PF07851.8 EOO02716.1 - 1.6 7.6 8.0 1.3 8.0 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein F-box-like PF12937.2 EOO02717.1 - 2.9e-10 39.6 0.9 1.2e-09 37.7 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EOO02717.1 - 8.1e-10 38.1 0.1 3.2e-09 36.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EOO02717.1 - 0.041 13.8 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 PRANC domain Aminotran_5 PF00266.14 EOO02718.1 - 6.6e-95 317.9 0.0 8.3e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EOO02718.1 - 2.6e-09 36.6 0.0 3.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EOO02718.1 - 6.7e-05 22.0 0.0 0.00023 20.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EOO02718.1 - 0.01 14.3 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EOO02718.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Lactamase_B_2 PF12706.2 EOO02718.1 - 0.09 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PPR_2 PF13041.1 EOO02719.1 - 1.9e-05 24.5 0.0 0.86 9.6 0.0 3.8 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 EOO02719.1 - 2.4e-05 24.2 1.9 0.27 11.6 0.0 4.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EOO02719.1 - 0.035 14.0 0.1 0.97 9.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Pkinase PF00069.20 EOO02721.1 - 2.8e-76 256.1 0.0 3.7e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02721.1 - 1.3e-37 129.2 0.0 1.8e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EOO02721.1 - 2.4e-16 59.6 0.2 4.6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EOO02721.1 - 4e-06 26.0 0.0 1.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EOO02721.1 - 0.0003 20.1 0.2 0.0006 19.2 0.2 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EOO02721.1 - 0.0026 16.4 0.1 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EOO02721.1 - 0.038 13.7 0.6 0.22 11.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NmrA PF05368.8 EOO02722.1 - 4.6e-12 45.7 0.0 8.3e-10 38.3 0.0 2.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO02722.1 - 4.8e-11 42.9 0.1 1.2e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EOO02722.1 - 0.00064 19.7 0.5 0.001 19.0 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EOO02722.1 - 0.00079 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ribosomal_L37ae PF01780.14 EOO02723.1 - 1.1e-29 102.1 4.2 1.3e-29 101.9 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EOO02723.1 - 0.00081 19.1 3.1 0.0013 18.4 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EOO02723.1 - 0.013 14.9 4.5 0.41 10.1 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.9 EOO02723.1 - 0.03 13.9 3.5 0.55 9.9 0.3 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif YyzF PF14116.1 EOO02723.1 - 0.14 12.1 0.7 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 YyzF-like protein Zn-ribbon_8 PF09723.5 EOO02723.1 - 0.15 12.0 1.8 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYND PF01753.13 EOO02723.1 - 0.16 11.8 3.3 0.29 11.0 2.3 1.4 1 0 0 1 1 1 0 MYND finger Ogr_Delta PF04606.7 EOO02723.1 - 0.2 11.3 1.8 0.48 10.1 1.3 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger C1_1 PF00130.17 EOO02723.1 - 0.26 11.0 3.2 0.38 10.5 2.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EOO02723.1 - 0.5 10.0 4.0 0.64 9.7 2.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.21 EOO02723.1 - 0.99 9.8 4.2 11 6.5 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Sec23_Sec24 PF04810.10 EOO02723.1 - 1.2 8.7 4.1 2.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 EOO02723.1 - 1.7 9.0 7.9 2.6 8.4 1.6 2.4 1 1 1 2 2 2 0 Zinc-finger double domain PHD PF00628.24 EOO02724.1 - 9.2e-10 38.0 5.1 9.2e-10 38.0 3.5 3.0 2 1 1 3 3 3 1 PHD-finger zf-RING_2 PF13639.1 EOO02724.1 - 2.4e-08 33.6 4.1 2.4e-08 33.6 2.8 4.2 3 1 1 4 4 3 1 Ring finger domain zf-rbx1 PF12678.2 EOO02724.1 - 3.8e-06 26.9 16.4 7.8e-06 25.9 5.3 3.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EOO02724.1 - 1.3e-05 24.7 2.2 1.3e-05 24.7 1.5 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02724.1 - 1.6e-05 24.5 3.5 1.6e-05 24.5 2.4 3.6 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EOO02724.1 - 6.3e-05 22.9 2.3 6.3e-05 22.9 1.6 3.9 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EOO02724.1 - 0.00026 20.2 1.9 0.00026 20.2 1.3 2.4 2 1 1 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 EOO02724.1 - 0.0005 19.7 2.3 0.0005 19.7 1.6 3.6 4 1 0 4 4 3 1 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 EOO02724.1 - 0.00054 19.7 3.0 0.00054 19.7 2.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 EOO02724.1 - 0.00068 18.9 1.5 0.0011 18.2 0.7 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EOO02724.1 - 0.0025 17.4 2.8 0.0025 17.4 2.0 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 EOO02724.1 - 0.02 14.2 7.2 0.027 13.7 1.1 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.1 EOO02724.1 - 0.071 12.8 0.4 0.071 12.8 0.3 3.0 3 0 0 3 3 2 0 RING-type zinc-finger DZR PF12773.2 EOO02724.1 - 0.67 9.8 9.4 14 5.6 4.6 3.0 2 1 0 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EOO02724.1 - 2 8.5 7.6 2.5 8.2 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase FANCL_C PF11793.3 EOO02724.1 - 2.3 8.2 8.8 0.19 11.7 0.7 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain DUF1644 PF07800.7 EOO02724.1 - 3.9 7.2 12.0 3.7 7.3 1.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1644) PHF5 PF03660.9 EOO02725.1 - 1.5e-51 172.8 10.6 1.7e-51 172.7 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EOO02725.1 - 1.1 9.1 15.9 8.4 6.3 1.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EOO02725.1 - 1.4 8.7 15.8 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EOO02725.1 - 4.4 4.8 5.8 4.4 4.8 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 EOO02725.1 - 7.1 6.4 15.5 0.2 11.3 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Cpn60_TCP1 PF00118.19 EOO02726.1 - 5.5e-138 460.6 6.2 6.3e-138 460.4 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 EOO02726.1 - 0.084 12.5 0.3 0.24 11.0 0.2 1.8 1 1 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Flavoprotein PF02441.14 EOO02727.1 - 1.9e-29 101.9 0.8 2.5e-29 101.5 0.5 1.1 1 0 0 1 1 1 1 Flavoprotein eIF-5_eIF-2B PF01873.12 EOO02728.1 - 8e-40 135.3 0.0 1.6e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EOO02728.1 - 9.6e-26 89.5 0.7 2.6e-25 88.1 0.5 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1754 PF08555.5 EOO02728.1 - 0.37 11.4 9.8 0.94 10.1 6.8 1.7 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_Rpb1_5 PF04998.12 EOO02728.1 - 1.7 7.8 5.3 8.6 5.5 3.7 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Cwf_Cwc_15 PF04889.7 EOO02729.1 - 2.3e-88 296.0 17.3 2.6e-88 295.8 12.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EOO02729.1 - 0.74 9.0 23.3 0.95 8.6 16.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EOO02729.1 - 0.87 7.4 23.9 0.93 7.3 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family Tom37_C PF11801.3 EOO02729.1 - 1.2 9.0 4.0 1.6 8.5 2.8 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Upf2 PF04050.9 EOO02729.1 - 1.4 8.6 21.5 2.4 7.8 14.9 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF2890 PF11081.3 EOO02729.1 - 1.6 8.7 20.7 2.5 8.1 14.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EOO02729.1 - 3.8 5.4 20.6 4.4 5.2 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EOO02729.1 - 6.3 6.2 19.4 9.2 5.7 13.5 1.2 1 0 0 1 1 1 0 PPP4R2 ABC_membrane PF00664.18 EOO02730.1 - 4.3e-85 285.4 40.8 1.4e-46 159.1 11.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EOO02730.1 - 7.5e-69 230.3 0.3 3.1e-33 114.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EOO02730.1 - 2.2e-13 49.9 0.0 0.00011 21.5 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EOO02730.1 - 5.4e-10 39.7 1.9 0.0083 16.1 0.1 4.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EOO02730.1 - 1.6e-09 38.0 0.2 0.0006 19.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EOO02730.1 - 1.6e-09 37.1 0.5 0.00016 21.0 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EOO02730.1 - 1.6e-07 32.1 0.1 0.011 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EOO02730.1 - 2e-07 29.9 2.4 0.0026 16.4 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EOO02730.1 - 1.5e-06 27.4 0.1 0.13 11.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 EOO02730.1 - 5e-06 26.7 1.9 3.1 8.0 0.0 4.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EOO02730.1 - 6.5e-05 22.4 0.3 0.36 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EOO02730.1 - 6.5e-05 23.3 2.3 0.11 12.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EOO02730.1 - 0.0002 21.5 2.6 0.24 11.5 0.1 3.6 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EOO02730.1 - 0.00039 20.3 0.0 0.74 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EOO02730.1 - 0.00087 19.6 1.8 0.51 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EOO02730.1 - 0.00099 19.0 0.0 2.3 8.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EOO02730.1 - 0.0014 18.4 1.8 2.1 8.3 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EOO02730.1 - 0.0019 17.9 0.2 4 7.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EOO02730.1 - 0.0052 16.3 3.4 3.1 7.3 0.0 4.1 4 1 0 4 4 4 1 AAA domain G-alpha PF00503.15 EOO02730.1 - 0.0061 15.2 0.0 0.74 8.4 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit AAA_10 PF12846.2 EOO02730.1 - 0.0066 15.9 3.4 4.1 6.7 0.0 4.2 4 1 0 4 4 4 1 AAA-like domain AAA_28 PF13521.1 EOO02730.1 - 0.013 15.5 1.4 1.4 8.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EOO02730.1 - 0.014 14.4 0.1 0.92 8.5 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.12 EOO02730.1 - 0.025 14.4 6.2 0.51 10.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EOO02730.1 - 0.035 13.7 1.1 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EOO02730.1 - 0.041 14.0 0.0 4.8 7.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase Rad17 PF03215.10 EOO02730.1 - 0.052 12.2 0.0 0.11 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EOO02730.1 - 0.087 11.9 0.0 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4381 PF14316.1 EOO02730.1 - 0.33 11.0 3.4 0.96 9.5 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) VirB3 PF05101.8 EOO02730.1 - 6 6.9 14.6 0.46 10.4 0.2 4.8 5 0 0 5 5 4 0 Type IV secretory pathway, VirB3-like protein Hydrolase_like PF13242.1 EOO02731.1 - 7.5e-07 28.7 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Cytokin_check_N PF10407.4 EOO02731.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus PH PF00169.24 EOO02732.1 - 0.00062 19.9 0.3 0.0027 17.8 0.2 2.1 1 1 0 1 1 1 1 PH domain GRAM PF02893.15 EOO02732.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Abhydrolase_6 PF12697.2 EOO02733.1 - 5.9e-31 108.1 0.2 1.1e-30 107.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO02733.1 - 3.7e-15 56.0 0.0 2.3e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO02733.1 - 2e-11 43.8 0.0 7.8e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EOO02733.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 EOO02733.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus MoaC PF01967.16 EOO02734.1 - 2.2e-25 88.8 0.1 2.9e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 MoaC family DUF1183 PF06682.7 EOO02735.1 - 1.3e-67 228.6 0.0 1.5e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EOO02736.1 - 0.00057 19.9 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Cript PF10235.4 EOO02737.1 - 2e-32 111.3 12.2 3.3e-32 110.6 8.5 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EOO02737.1 - 0.0017 18.3 6.5 0.0017 18.3 4.5 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 EOO02737.1 - 0.025 14.3 13.3 0.052 13.3 3.1 2.8 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EOO02737.1 - 0.43 10.1 15.4 0.068 12.6 3.1 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EOO02737.1 - 0.61 9.3 13.3 4.6 6.5 5.0 3.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 EOO02737.1 - 1.1 9.0 13.9 17 5.2 7.4 3.0 2 1 1 3 3 3 0 zinc-RING finger domain DUF1272 PF06906.6 EOO02737.1 - 2.8 7.8 8.0 0.25 11.2 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prim_Zn_Ribbon PF08273.7 EOO02737.1 - 6.6 6.8 11.9 14 5.8 0.0 3.3 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Ribosomal_L32p PF01783.18 EOO02737.1 - 6.8 6.9 9.9 0.98 9.6 3.4 2.2 2 1 0 2 2 2 0 Ribosomal L32p protein family AAA PF00004.24 EOO02738.1 - 1.4e-08 34.9 0.0 3.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EOO02738.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EOO02738.1 - 0.0045 17.8 5.8 0.0048 17.7 0.0 3.6 4 1 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EOO02738.1 - 0.017 15.2 0.0 0.06 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EOO02738.1 - 0.019 15.2 0.1 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EOO02738.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EOO02738.1 - 0.063 13.2 0.0 0.063 13.2 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 EOO02738.1 - 0.21 11.3 0.2 0.45 10.2 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain PH_10 PF15411.1 EOO02739.1 - 2.8e-26 91.9 0.1 4.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EOO02739.1 - 2.4e-10 40.3 0.0 7.7e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EOO02739.1 - 1.4e-07 31.3 0.1 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SR-25 PF10500.4 EOO02740.1 - 0.0013 18.2 0.1 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MRP-L46 PF11788.3 EOO02741.1 - 1.2e-24 87.1 0.1 2.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EOO02741.1 - 0.0003 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ELO PF01151.13 EOO02742.1 - 2e-85 286.0 2.9 2.5e-85 285.7 2.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family XPC-binding PF09280.6 EOO02743.1 - 3.3e-24 84.1 12.8 6.9e-24 83.0 8.9 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EOO02743.1 - 8.9e-19 66.6 1.2 1.5e-18 65.9 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EOO02743.1 - 1.7e-16 59.4 4.3 1.4e-09 37.4 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EOO02743.1 - 2.7e-10 39.7 0.8 4.9e-10 38.9 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EOO02743.1 - 0.00028 21.3 0.1 0.00075 19.9 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EOO02743.1 - 0.0016 17.9 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Peptidase_S8 PF00082.17 EOO02743.1 - 0.0035 16.5 1.4 0.0048 16.0 0.9 1.3 1 0 0 1 1 1 1 Subtilase family DUF2407 PF10302.4 EOO02743.1 - 0.0046 17.1 0.0 0.0099 16.0 0.0 1.7 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EOO02743.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EOO02743.1 - 0.042 14.0 0.1 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain eIF-5a PF01287.15 EOO02743.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TPR_16 PF13432.1 EOO02745.1 - 6.3e-07 29.9 5.1 0.0025 18.4 1.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EOO02745.1 - 0.00042 19.8 0.1 0.061 12.9 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EOO02745.1 - 0.0005 19.7 0.1 0.13 12.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EOO02745.1 - 0.0037 17.7 1.6 0.0037 17.7 1.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EOO02745.1 - 0.0044 16.5 0.0 0.46 10.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EOO02745.1 - 0.36 11.4 0.1 0.36 11.4 0.1 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Kazal_1 PF00050.16 EOO02746.1 - 0.075 13.0 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Ins_P5_2-kin PF06090.7 EOO02747.1 - 6.5e-46 156.8 0.0 1.2e-33 116.4 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase AAA PF00004.24 EOO02748.1 - 5.3e-99 327.5 0.0 3.5e-48 163.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EOO02748.1 - 5.4e-19 67.9 0.6 2.2e-18 65.9 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EOO02748.1 - 4.1e-14 52.8 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EOO02748.1 - 8e-14 51.2 0.0 3.5e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EOO02748.1 - 4.4e-13 49.1 0.6 9.4e-07 28.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EOO02748.1 - 1.1e-12 47.9 0.0 1.6e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EOO02748.1 - 1.5e-12 47.8 0.2 0.00061 19.9 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EOO02748.1 - 8.9e-12 45.3 0.0 0.00029 20.8 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EOO02748.1 - 1.5e-11 45.1 0.0 0.00033 21.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 EOO02748.1 - 1.6e-09 36.9 0.1 0.00087 18.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EOO02748.1 - 6.6e-09 35.7 0.0 0.0014 18.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EOO02748.1 - 1e-08 34.8 0.0 0.002 17.6 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EOO02748.1 - 1.3e-08 34.4 5.9 0.037 13.4 0.0 4.8 3 2 2 5 5 5 3 AAA domain Zeta_toxin PF06414.7 EOO02748.1 - 1.1e-07 31.1 0.2 0.011 14.8 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 EOO02748.1 - 1.6e-07 30.9 1.9 0.017 14.8 0.2 3.2 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EOO02748.1 - 1.8e-07 30.5 0.3 0.0055 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EOO02748.1 - 3.3e-07 29.8 0.0 9.8e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 EOO02748.1 - 8.1e-07 29.1 0.0 0.039 14.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EOO02748.1 - 8.8e-07 28.2 0.5 0.23 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 EOO02748.1 - 9.4e-07 28.6 0.0 0.049 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EOO02748.1 - 1.8e-06 28.2 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EOO02748.1 - 1.8e-06 27.0 0.0 0.012 14.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_28 PF13521.1 EOO02748.1 - 2.9e-06 27.3 0.0 0.078 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EOO02748.1 - 3.6e-06 27.0 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EOO02748.1 - 3.6e-06 26.8 0.0 2.6 7.6 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase ResIII PF04851.10 EOO02748.1 - 5.1e-06 26.4 0.0 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EOO02748.1 - 8.6e-06 25.3 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EOO02748.1 - 1e-05 24.5 0.0 0.058 12.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 EOO02748.1 - 1.1e-05 25.2 0.3 3.9e-05 23.4 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 EOO02748.1 - 1.6e-05 25.2 0.0 0.2 11.9 0.0 3.6 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 EOO02748.1 - 1.9e-05 24.4 0.0 0.22 11.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein NACHT PF05729.7 EOO02748.1 - 2.2e-05 24.1 0.0 0.12 12.0 0.0 3.2 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.11 EOO02748.1 - 8.3e-05 21.8 0.2 0.33 10.1 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EOO02748.1 - 0.00018 21.1 0.0 0.58 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EOO02748.1 - 0.0002 21.0 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EOO02748.1 - 0.00021 20.2 0.1 0.24 10.2 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.1 EOO02748.1 - 0.00052 19.6 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EOO02748.1 - 0.0021 17.1 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EOO02748.1 - 0.0027 17.4 0.3 2.2 7.9 0.0 3.8 3 0 0 3 3 3 1 NTPase IPT PF01745.11 EOO02748.1 - 0.0038 16.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase KAP_NTPase PF07693.9 EOO02748.1 - 0.0092 15.0 0.5 1.1 8.2 0.0 3.4 2 2 1 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.13 EOO02748.1 - 0.017 14.6 0.0 0.79 9.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EOO02748.1 - 0.024 14.2 0.1 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 EOO02748.1 - 0.037 13.4 0.2 13 5.2 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) SKI PF01202.17 EOO02748.1 - 0.043 13.6 0.1 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 EOO02748.1 - 0.048 12.5 0.0 2.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.11 EOO02748.1 - 0.058 12.2 0.0 6.7 5.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_10 PF12846.2 EOO02748.1 - 0.079 12.3 0.8 3.5 6.9 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain MobB PF03205.9 EOO02748.1 - 0.08 12.6 1.2 2.4 7.8 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EOO02748.1 - 0.081 12.1 0.3 8.8 5.4 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 EOO02748.1 - 0.088 13.1 0.0 5 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Nucleoside_tran PF01733.13 EOO02750.1 - 2.8e-39 135.1 1.5 1.5e-38 132.6 1.1 2.1 1 1 0 1 1 1 1 Nucleoside transporter Scs3p PF10261.4 EOO02750.1 - 0.043 12.8 1.9 0.26 10.2 0.0 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Catalase PF00199.14 EOO02751.1 - 4.7e-76 255.9 0.0 6.1e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EOO02751.1 - 2.8e-19 68.7 0.0 4.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive PBP PF01161.15 EOO02752.1 - 3.4e-21 75.6 0.0 4.1e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF77 PF01910.12 EOO02753.1 - 3.9e-33 113.0 0.3 4.4e-33 112.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EOO02753.1 - 0.034 14.2 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family SYF2 PF08231.7 EOO02754.1 - 1.2e-52 178.1 17.6 1.2e-52 178.1 12.2 2.3 2 1 0 2 2 2 1 SYF2 splicing factor Plasmid_RAQPRD PF09686.5 EOO02754.1 - 2.4 8.3 8.3 6.8 6.8 2.6 3.0 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Mob_synth_C PF06463.8 EOO02755.1 - 1.8e-36 124.6 0.1 9.5e-36 122.3 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EOO02755.1 - 1.1e-18 67.9 0.0 2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EOO02755.1 - 6.7e-05 23.0 0.0 0.00041 20.4 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EOO02755.1 - 0.00013 22.0 0.0 0.00051 20.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain RRM_1 PF00076.17 EOO02756.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02756.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02756.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3074 PF11274.3 EOO02757.1 - 1.4e-56 191.0 8.1 1.4e-55 187.7 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 EOO02757.1 - 0.0042 16.5 39.0 0.0042 16.5 27.0 3.0 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TPR_MLP1_2 PF07926.7 EOO02757.1 - 0.93 9.2 34.1 1.9 8.2 22.9 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EOO02757.1 - 4.4 5.6 31.2 0.25 9.7 17.0 1.9 2 0 0 2 2 2 0 AAA domain AA_permease PF00324.16 EOO02760.1 - 3.9e-140 467.3 36.8 4.5e-140 467.1 25.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO02760.1 - 3.6e-44 150.9 40.1 4.6e-44 150.6 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease RNase_PH PF01138.16 EOO02761.1 - 6.2e-23 81.5 0.0 1.4e-22 80.4 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EOO02761.1 - 4.7e-06 26.4 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mitofilin PF09731.4 EOO02762.1 - 1.7 7.2 27.6 2.5 6.6 19.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 EOO02762.1 - 2.8 5.5 23.7 4.3 4.8 16.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U3_snoRNA_assoc PF08297.6 EOO02763.1 - 2.4e-10 40.4 0.6 2.4e-10 40.4 0.4 4.0 4 2 0 4 4 4 1 U3 snoRNA associated DUF1749 PF08538.5 EOO02764.1 - 4.9e-69 232.5 0.0 6e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EOO02764.1 - 1.2e-09 38.4 0.0 1.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02764.1 - 0.0001 22.1 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO02764.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EOO02764.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.10 EOO02764.1 - 0.023 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase YEATS PF03366.11 EOO02765.1 - 2e-29 101.1 0.2 3e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 YEATS family Pyr_redox_2 PF07992.9 EOO02766.1 - 1.4e-26 93.6 0.0 1.8e-25 90.0 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO02766.1 - 1.1e-13 51.3 0.0 7.6e-12 45.4 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO02766.1 - 0.00085 19.4 0.1 0.67 9.9 0.0 3.5 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EOO02766.1 - 0.18 12.1 0.5 23 5.3 0.3 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding E1-E2_ATPase PF00122.15 EOO02767.1 - 2.1e-23 82.5 0.0 3.4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EOO02767.1 - 1.2e-20 74.5 0.3 3e-20 73.2 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EOO02767.1 - 3.3e-15 57.0 2.6 6.6e-14 52.8 1.8 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO02767.1 - 9.7e-13 47.8 0.0 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EOO02767.1 - 0.00061 19.4 0.0 0.0069 15.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EOO02767.1 - 0.037 14.2 0.3 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pinin_SDK_memA PF04696.8 EOO02768.1 - 1.5e-27 95.8 16.1 1.5e-27 95.8 11.1 1.8 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF2422 PF10337.4 EOO02768.1 - 7.4 5.2 9.3 9.9 4.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Acetyltransf_1 PF00583.19 EOO02769.1 - 9.7e-09 35.1 0.0 1.4e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EOO02769.1 - 5.9e-08 32.7 0.0 1.7e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EOO02769.1 - 6e-06 26.0 0.0 9.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EOO02769.1 - 8.9e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EOO02769.1 - 4.3e-05 23.3 0.0 0.14 11.9 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EOO02769.1 - 7.3e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EOO02769.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.14 EOO02770.1 - 3.6e-47 160.9 0.3 5e-47 160.4 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO02770.1 - 6.8e-25 88.0 1.3 1.3e-24 87.1 0.0 2.1 2 1 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EOO02770.1 - 4.1e-09 35.8 1.7 6.4e-05 22.0 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO02770.1 - 3e-08 33.7 0.1 5.2e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO02770.1 - 1.1e-07 31.0 4.6 2.6e-07 29.8 3.2 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EOO02770.1 - 7.9e-06 25.8 3.3 1.5e-05 24.8 0.8 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EOO02770.1 - 0.0001 21.4 0.4 0.00019 20.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EOO02770.1 - 0.0001 21.4 2.9 0.0018 17.4 0.1 2.8 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 EOO02770.1 - 0.0019 16.7 0.9 0.0046 15.4 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 EOO02770.1 - 0.041 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EOO02770.1 - 0.067 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EOO02770.1 - 0.11 11.9 2.2 0.17 11.2 1.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EOO02770.1 - 0.13 11.3 1.3 0.21 10.6 0.8 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EOO02770.1 - 0.18 10.6 0.1 1.3 7.8 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.13 EOO02770.1 - 0.27 9.4 0.0 0.7 8.1 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor DUF155 PF02582.9 EOO02771.1 - 4.6e-55 186.2 0.4 7.9e-55 185.4 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 NAD_binding_4 PF07993.7 EOO02772.1 - 0.0083 15.0 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EOO02772.1 - 0.036 14.0 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding HMG_box PF00505.14 EOO02773.1 - 1.4e-09 38.1 5.8 2.3e-09 37.3 2.9 2.3 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EOO02773.1 - 0.00068 19.9 3.5 0.00068 19.9 2.5 3.0 2 1 1 3 3 3 1 HMG-box domain Sec31 PF11549.3 EOO02773.1 - 0.2 11.3 1.7 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein transport protein SEC31 ATP-synt_E PF05680.7 EOO02773.1 - 3.6 7.5 10.9 32 4.5 0.1 2.4 2 0 0 2 2 2 0 ATP synthase E chain DUF1682 PF07946.9 EOO02774.1 - 2.7e-102 341.8 2.4 3.2e-102 341.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.3 EOO02774.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Glyco_hydro_35 PF01301.14 EOO02775.1 - 2.5e-71 240.6 3.2 5.1e-71 239.6 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EOO02775.1 - 1.6e-50 171.0 6.4 3e-50 170.0 4.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EOO02775.1 - 2e-49 166.5 6.5 1e-25 90.1 0.0 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EOO02775.1 - 2.7e-22 77.9 0.5 1e-21 76.0 0.1 2.2 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EOO02775.1 - 2.7e-06 26.7 0.0 0.0019 17.3 0.0 2.8 2 1 1 3 3 3 2 Beta-galactosidase Cellulase PF00150.13 EOO02775.1 - 0.0098 15.1 0.4 0.15 11.2 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) YecM PF06185.7 EOO02775.1 - 0.014 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 YecM protein UPF1_Zn_bind PF09416.5 EOO02776.1 - 4.2e-72 240.7 3.5 1.6e-71 238.8 0.7 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EOO02776.1 - 1e-60 204.5 0.0 2.4e-60 203.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EOO02776.1 - 3.6e-57 193.6 2.7 6.7e-57 192.7 1.8 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02776.1 - 4.1e-14 52.0 0.6 1e-13 50.8 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EOO02776.1 - 4.6e-12 45.9 0.3 1.3e-10 41.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EOO02776.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EOO02776.1 - 1.9e-05 24.4 0.1 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EOO02776.1 - 7.1e-05 22.4 0.1 0.75 9.2 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EOO02776.1 - 7.9e-05 21.7 0.5 0.00069 18.6 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EOO02776.1 - 0.00023 20.5 0.1 0.0058 15.9 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EOO02776.1 - 0.00023 20.2 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 EOO02776.1 - 0.00062 19.3 0.2 0.0016 17.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EOO02776.1 - 0.0024 17.3 0.1 0.0056 16.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 EOO02776.1 - 0.0037 16.4 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 KaiC CbiA PF01656.18 EOO02776.1 - 0.039 13.3 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 EOO02776.1 - 0.041 13.3 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EOO02776.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EOO02776.1 - 0.049 13.0 0.0 0.28 10.5 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain PhoH PF02562.11 EOO02776.1 - 0.064 12.4 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein UvrD_C_2 PF13538.1 EOO02776.1 - 0.08 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SNF2_N PF00176.18 EOO02776.1 - 0.085 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EOO02776.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EOO02776.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_S13_N PF08069.7 EOO02776.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_25 PF13481.1 EOO02776.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3602 PF12223.3 EOO02776.1 - 0.22 11.9 4.1 0.61 10.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) Pro-kuma_activ PF09286.6 EOO02778.1 - 6.3e-39 133.2 0.0 1.7e-38 131.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EOO02778.1 - 7.8e-05 21.9 0.0 0.00017 20.8 0.0 1.5 1 1 0 1 1 1 1 Subtilase family AhpC-TSA_2 PF13911.1 EOO02779.1 - 1.1e-18 67.1 0.0 3.5e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Phosphoprotein PF00922.12 EOO02779.1 - 0.068 12.3 3.4 0.046 12.9 0.4 1.9 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Brix PF04427.13 EOO02780.1 - 1.5e-44 151.9 0.1 1.8e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain Aminotran_4 PF01063.14 EOO02781.1 - 7.5e-26 91.0 0.0 9.6e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DEK_C PF08766.6 EOO02781.1 - 0.054 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 DEK C terminal domain CPSF_A PF03178.10 EOO02783.1 - 1.1e-100 336.8 0.0 2.3e-100 335.8 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 EOO02783.1 - 1.8e-67 227.6 0.0 2.5e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1945 PF09178.5 EOO02783.1 - 0.084 12.7 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) HK PF02110.10 EOO02785.1 - 7.8e-78 261.0 3.5 7.8e-78 261.0 2.4 1.9 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EOO02785.1 - 9.3e-58 194.2 1.7 1.4e-57 193.7 0.6 1.8 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Isochorismatase PF00857.15 EOO02785.1 - 3.8e-31 108.3 0.7 6.5e-30 104.3 0.1 2.8 3 1 0 3 3 3 1 Isochorismatase family Carb_kinase PF01256.12 EOO02785.1 - 0.00073 18.8 0.4 0.0017 17.7 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate kinase PDT PF00800.13 EOO02786.1 - 2e-39 135.0 0.0 1.6e-38 132.0 0.0 2.0 1 1 1 2 2 2 1 Prephenate dehydratase ACT PF01842.20 EOO02786.1 - 0.00031 20.1 0.0 0.0018 17.7 0.0 2.2 3 0 0 3 3 3 1 ACT domain UAA PF08449.6 EOO02787.1 - 4.3e-11 42.2 18.0 4.7e-11 42.1 9.8 1.9 1 1 1 2 2 2 1 UAA transporter family TPT PF03151.11 EOO02787.1 - 3.8e-07 29.8 7.8 3.8e-07 29.8 5.4 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EOO02787.1 - 5.4e-05 23.2 26.5 0.0037 17.3 6.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family WD40 PF00400.27 EOO02788.1 - 4e-71 232.5 11.8 7e-11 41.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EOO02788.1 - 2.2e-24 85.4 9.4 3.5e-24 84.7 6.5 1.2 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EOO02788.1 - 0.00027 19.2 0.9 0.64 8.0 0.0 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EOO02788.1 - 0.001 17.9 0.2 0.32 9.6 0.1 3.3 1 1 3 4 4 4 2 Nup133 N terminal like Filament PF00038.16 EOO02788.1 - 0.012 15.0 2.7 0.018 14.5 1.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Cytochrom_D1 PF02239.11 EOO02788.1 - 0.014 13.7 0.5 0.84 7.8 0.1 2.6 2 1 2 4 4 4 0 Cytochrome D1 heme domain LXG PF04740.7 EOO02788.1 - 0.015 15.0 0.5 0.023 14.5 0.4 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nbas_N PF15492.1 EOO02788.1 - 0.072 12.1 0.0 18 4.3 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF2360 PF10152.4 EOO02788.1 - 6.8 6.9 12.0 1.4e+02 2.7 8.3 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 EOO02789.1 - 1.1e-69 234.4 0.0 2.1e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02789.1 - 9.7e-50 169.0 0.0 1.6e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EOO02789.1 - 2.1e-28 98.3 0.0 5.1e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EOO02789.1 - 4.4e-17 61.6 0.3 2.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EOO02789.1 - 1.9e-15 56.7 0.1 3.5e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EOO02789.1 - 1.8e-12 47.5 0.1 3.5e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EOO02789.1 - 2.4e-08 33.2 0.0 2.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 EOO02789.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain FlgD_ig PF13860.1 EOO02789.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain DUF3500 PF12006.3 EOO02790.1 - 0.024 13.5 0.3 0.034 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) YjfB_motility PF14070.1 EOO02790.1 - 0.054 13.2 0.8 0.054 13.2 0.5 1.8 2 0 0 2 2 2 0 Putative motility protein AP4E_app_platf PF14807.1 EOO02790.1 - 0.099 12.8 1.0 0.24 11.6 0.2 1.9 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform ARD PF03079.9 EOO02791.1 - 8.6e-45 152.5 0.1 1e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EOO02791.1 - 2.5e-09 36.4 0.1 4.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EOO02791.1 - 2.2e-06 27.4 0.1 2.8e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EOO02791.1 - 0.0023 17.3 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin adh_short PF00106.20 EOO02792.1 - 9.6e-17 61.3 0.0 1.4e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02792.1 - 8.9e-08 32.0 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 KR domain SDH_alpha PF03313.10 EOO02792.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain Brix PF04427.13 EOO02793.1 - 1e-33 116.5 0.0 1.5e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain Daxx PF03344.10 EOO02793.1 - 0.033 12.6 11.5 0.042 12.3 8.0 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EOO02793.1 - 0.08 10.8 24.7 0.1 10.5 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family AMPKBI PF04739.10 EOO02793.1 - 0.13 12.0 0.4 0.31 10.9 0.2 1.6 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain RRN3 PF05327.6 EOO02793.1 - 1.9 6.4 7.8 2.8 5.9 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.17 EOO02793.1 - 4.5 6.1 4.9 6 5.7 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter ATP-synt_C PF00137.16 EOO02794.1 - 1.2e-18 66.7 15.0 1.3e-16 60.1 7.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EOO02794.1 - 0.13 11.3 1.9 0.18 10.9 0.8 1.6 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor TCR_zetazeta PF11628.3 EOO02794.1 - 0.43 10.0 2.8 3.3 7.2 0.3 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF3816 PF12822.2 EOO02794.1 - 0.57 10.0 7.9 0.8 9.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Lipase_GDSL_2 PF13472.1 EOO02795.1 - 1.3e-18 67.7 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO02795.1 - 9.5e-17 61.5 0.0 1.1e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EOO02795.1 - 0.092 12.4 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 EOO02796.1 - 3.9e-57 193.3 0.0 7.4e-57 192.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02796.1 - 3.5e-32 111.4 0.0 1.8e-30 105.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EOO02796.1 - 1.5e-09 37.2 0.0 5e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EOO02796.1 - 0.00055 19.7 0.3 0.0013 18.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EOO02797.1 - 3.1e-55 187.1 0.0 5.2e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02797.1 - 1.3e-30 106.3 0.0 2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02797.1 - 4.3e-11 42.2 0.0 8.6e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Ribosomal_L2_C PF03947.13 EOO02798.1 - 1.6e-37 128.1 4.6 2.8e-37 127.4 3.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EOO02798.1 - 1.3e-14 53.8 0.1 2.6e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 EOO02798.1 - 0.098 12.2 0.3 0.22 11.1 0.1 1.6 2 0 0 2 2 2 0 Surface presentation of antigens (SPOA) SPC12 PF06645.8 EOO02799.1 - 7.2e-28 96.2 0.1 8.5e-28 95.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) PfkB PF00294.19 EOO02800.1 - 1.2e-66 224.9 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EOO02800.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Alpha-amylase PF00128.19 EOO02801.1 - 5.7e-45 154.0 0.2 6.4e-45 153.9 0.2 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EOO02801.1 - 0.0016 17.4 0.0 0.0018 17.2 0.0 1.0 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme HSA PF07529.8 EOO02802.1 - 2.3e-21 75.3 1.5 2.3e-21 75.3 1.0 3.4 3 0 0 3 3 3 2 HSA Myb_DNA-bind_6 PF13921.1 EOO02802.1 - 3.3e-14 52.7 1.7 3.3e-14 52.7 1.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EOO02802.1 - 0.0013 18.7 0.4 0.0037 17.2 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain EVI2A PF05399.6 EOO02802.1 - 0.098 11.8 1.6 0.22 10.7 1.1 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) G-patch_2 PF12656.2 EOO02803.1 - 4.1e-13 48.9 0.4 4.1e-13 48.9 0.3 3.3 4 2 0 4 4 4 1 DExH-box splicing factor binding site DUF4598 PF15370.1 EOO02803.1 - 0.016 15.4 4.5 0.016 15.4 3.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) Abi PF02517.11 EOO02804.1 - 2.9e-13 49.7 11.9 2.9e-13 49.7 8.2 2.8 2 1 1 3 3 3 1 CAAX protease self-immunity eRF1_2 PF03464.10 EOO02807.1 - 5.4e-46 156.2 0.1 1e-45 155.3 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EOO02807.1 - 5.6e-41 139.3 0.9 1.1e-40 138.3 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EOO02807.1 - 2.4e-28 98.3 0.0 4.9e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 zf-Mss51 PF13824.1 EOO02808.1 - 1.5e-07 31.1 1.5 3e-07 30.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 AAA_12 PF13087.1 EOO02809.1 - 3.4e-28 98.4 0.0 5.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EOO02809.1 - 2.1e-23 83.1 0.0 4e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO02809.1 - 1.1e-09 37.9 0.0 1.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EOO02809.1 - 2.2e-06 27.3 0.0 0.00091 18.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EOO02809.1 - 8.8e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EOO02809.1 - 0.0019 17.5 0.0 0.0047 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EOO02809.1 - 0.0023 18.1 0.0 0.0091 16.1 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EOO02809.1 - 0.0035 16.8 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 EOO02809.1 - 0.0051 17.6 0.2 0.33 11.7 0.1 3.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EOO02809.1 - 0.0051 16.3 0.1 0.3 10.5 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EOO02809.1 - 0.0054 16.8 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO02809.1 - 0.01 15.8 2.0 0.11 12.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 EOO02809.1 - 0.014 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.10 EOO02809.1 - 0.026 13.3 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD-helicase PF00580.16 EOO02809.1 - 0.038 13.2 1.3 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EOO02809.1 - 0.041 12.8 0.0 0.041 12.8 0.0 2.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EOO02809.1 - 0.067 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EOO02809.1 - 0.072 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase PIF1 PF05970.9 EOO02809.1 - 0.13 11.1 0.1 13 4.5 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase Parvo_NS1 PF01057.12 EOO02809.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EOO02809.1 - 0.19 11.8 0.0 0.55 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RecA PF00154.16 EOO02809.1 - 0.24 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PXA PF02194.10 EOO02810.1 - 1.1e-39 135.8 0.0 1.8e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 PXA domain RNA_pol_L_2 PF13656.1 EOO02811.1 - 2.5e-30 103.7 0.0 3.4e-30 103.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EOO02811.1 - 1.7e-11 43.0 0.0 2.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UPF0160 PF03690.8 EOO02811.1 - 0.045 13.1 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) TRAP_alpha PF03896.11 EOO02811.1 - 0.65 8.9 2.7 0.77 8.6 1.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2146 PF10220.4 EOO02811.1 - 1.1 7.1 3.8 1.4 6.8 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Tankyrase_bdg_C PF15327.1 EOO02811.1 - 1.5 8.9 5.3 2.1 8.4 3.7 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain DUF3321 PF11968.3 EOO02812.1 - 1.8e-48 165.0 0.0 2e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) SNF2_N PF00176.18 EOO02813.1 - 6.9e-45 153.1 0.0 1.5e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EOO02813.1 - 1.1e-13 50.8 0.1 3.8e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HNOB PF07700.10 EOO02813.1 - 0.64 9.5 2.1 7.1 6.1 0.7 2.4 2 0 0 2 2 2 0 Heme NO binding 2OG-FeII_Oxy_2 PF13532.1 EOO02814.1 - 5.6e-13 49.1 0.0 2.7e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EOO02814.1 - 6.9e-06 26.2 0.0 1.9e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.13 EOO02815.1 - 2.1e-53 181.2 30.5 2.7e-53 180.9 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_30 PF02055.11 EOO02816.1 - 1.9e-20 72.5 3.6 9.5e-20 70.2 2.5 1.9 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EOO02816.1 - 3e-13 49.4 0.2 5.6e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Aminotran_1_2 PF00155.16 EOO02817.1 - 1.4e-82 277.5 0.0 1.8e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EOO02817.1 - 4.9e-05 22.2 0.1 0.00013 20.7 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EOO02817.1 - 5.5e-05 21.6 0.0 9.3e-05 20.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3405 PF11885.3 EOO02817.1 - 0.0024 16.1 0.0 0.0035 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sec1 PF00995.18 EOO02818.1 - 7.4e-138 460.6 0.7 1.3e-104 350.9 1.8 2.0 1 1 1 2 2 2 2 Sec1 family B12-binding PF02310.14 EOO02818.1 - 0.018 14.9 0.1 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain FIST PF08495.5 EOO02818.1 - 0.035 13.2 0.0 0.98 8.5 0.0 2.3 2 0 0 2 2 2 0 FIST N domain DUF1649 PF07855.7 EOO02820.1 - 1.2e-58 197.3 0.5 4.6e-57 192.2 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) INSIG PF07281.7 EOO02821.1 - 4.2e-55 186.1 0.3 5.3e-55 185.7 0.2 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GIDA PF01134.17 EOO02822.1 - 1.3e-158 527.9 0.0 1.6e-158 527.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EOO02822.1 - 4.1e-14 52.3 0.0 1.1e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EOO02822.1 - 3.1e-07 30.4 0.2 6.3e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO02822.1 - 3.5e-07 29.6 0.2 5.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EOO02822.1 - 0.00012 21.1 2.2 0.23 10.3 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO02822.1 - 0.00025 20.0 1.8 0.00064 18.6 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EOO02822.1 - 0.0024 17.4 0.3 0.0051 16.3 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EOO02822.1 - 0.076 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO02822.1 - 0.11 10.9 3.5 0.31 9.4 0.5 2.3 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 EOO02822.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding EF-hand_4 PF12763.2 EOO02823.1 - 1.3e-27 95.5 0.0 7e-15 54.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EOO02823.1 - 0.00016 21.7 0.2 0.27 11.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EOO02823.1 - 0.0002 20.9 0.1 0.92 9.5 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EOO02823.1 - 0.00041 19.4 0.0 0.68 9.3 0.0 2.5 2 0 0 2 2 2 2 EF hand DUF1720 PF08226.6 EOO02823.1 - 0.0025 17.8 34.5 0.0025 17.8 23.9 7.0 5 3 2 7 7 7 2 Domain of unknown function (DUF1720) E3_binding PF02817.12 EOO02823.1 - 0.16 11.6 2.7 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 e3 binding domain Sybindin PF04099.7 EOO02824.1 - 1.2e-23 83.3 0.0 1.5e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EOO02824.1 - 0.05 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region CD24 PF14984.1 EOO02824.1 - 0.59 9.9 3.6 0.95 9.3 2.5 1.3 1 0 0 1 1 1 0 CD24 protein Alpha-amylase PF00128.19 EOO02825.1 - 3.4e-23 82.5 0.1 7.7e-23 81.3 0.0 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_42C PF08533.5 EOO02825.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain YopX PF09643.5 EOO02825.1 - 0.04 13.8 0.3 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 YopX protein Alpha-amylase_C PF02806.13 EOO02825.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain CorA PF01544.13 EOO02826.1 - 8.2e-40 136.6 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RsgI_N PF12791.2 EOO02826.1 - 0.07 12.8 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma factor N-terminus NAD_binding_8 PF13450.1 EOO02828.1 - 1e-12 47.8 0.1 2.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO02828.1 - 1.8e-09 36.9 0.1 1.5e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO02828.1 - 2.8e-08 33.8 0.2 1.8e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO02828.1 - 3e-08 32.9 0.8 5.1e-08 32.1 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EOO02828.1 - 7.2e-07 29.5 0.2 0.00097 19.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO02828.1 - 4.2e-06 26.0 0.0 8.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EOO02828.1 - 9.6e-06 24.9 0.6 0.00037 19.6 0.0 2.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO02828.1 - 1.7e-05 23.4 0.7 0.00017 20.1 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EOO02828.1 - 3.3e-05 23.7 0.2 0.0009 19.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EOO02828.1 - 0.00011 21.2 0.1 0.00023 20.2 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EOO02828.1 - 0.00029 20.9 0.2 0.00066 19.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EOO02828.1 - 0.006 15.7 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EOO02828.1 - 0.021 13.9 0.1 0.048 12.7 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EOO02828.1 - 0.021 13.4 0.2 0.037 12.6 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_S9 PF00326.16 EOO02828.1 - 0.022 14.0 0.1 0.049 12.8 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.14 EOO02828.1 - 0.032 13.3 0.0 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.1 EOO02828.1 - 0.046 12.6 0.0 0.67 8.8 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EOO02828.1 - 0.072 13.3 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.11 EOO02828.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EOO02828.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 EOO02828.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain GIDA PF01134.17 EOO02828.1 - 0.3 9.9 0.7 0.44 9.3 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CDP-OH_P_transf PF01066.16 EOO02829.1 - 1.7e-15 57.1 11.3 3.2e-15 56.2 7.8 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase adh_short PF00106.20 EOO02830.1 - 1.3e-31 109.7 0.2 1.6e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO02830.1 - 4.2e-24 85.6 0.0 5.3e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO02830.1 - 1e-13 51.3 0.3 1.4e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EOO02830.1 - 2.7e-05 23.4 0.0 0.00028 20.1 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) DFP PF04127.10 EOO02830.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.15 EOO02830.1 - 0.0063 16.6 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EOO02830.1 - 0.013 14.8 0.1 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.13 EOO02830.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EOO02830.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 EOO02830.1 - 0.034 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EOO02830.1 - 0.039 14.3 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EOO02830.1 - 0.084 12.7 0.2 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RmlD_sub_bind PF04321.12 EOO02830.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EOO02830.1 - 0.11 11.9 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.20 EOO02831.1 - 3e-62 210.1 0.0 5.8e-62 209.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02831.1 - 5e-26 91.3 0.0 7.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02831.1 - 0.0047 15.9 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO02831.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EOO02831.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EOO02831.1 - 0.1 12.3 0.3 0.83 9.3 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-rbx1 PF12678.2 EOO02832.1 - 4.4e-35 119.6 13.5 5.4e-35 119.3 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EOO02832.1 - 4.3e-17 61.7 9.8 5.6e-17 61.3 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EOO02832.1 - 4.6e-07 29.5 11.6 3e-06 26.9 8.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EOO02832.1 - 0.0013 18.3 11.3 0.022 14.4 7.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EOO02832.1 - 0.0038 16.8 9.7 0.45 10.2 6.9 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO02832.1 - 0.051 13.6 12.5 0.055 13.4 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02832.1 - 0.56 9.9 11.7 5.2 6.8 8.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EOO02832.1 - 0.87 9.5 9.3 4.9 7.2 6.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EOO02832.1 - 1.9 8.3 7.0 45 3.8 4.9 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EOO02832.1 - 1.9 8.6 10.8 1.1 9.3 0.6 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF2404 PF10296.4 EOO02833.1 - 4.9e-08 32.9 0.0 1.2e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Pep3_Vps18 PF05131.9 EOO02834.1 - 1.1e-50 170.8 0.1 2.9e-50 169.5 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EOO02834.1 - 1.6e-10 40.7 3.3 1.2e-07 31.4 0.0 3.5 2 1 1 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EOO02834.1 - 0.00039 20.1 1.2 0.00039 20.1 0.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EOO02834.1 - 0.0016 18.0 1.3 0.0016 18.0 0.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain DUF2175 PF09943.4 EOO02834.1 - 0.012 15.6 0.8 0.035 14.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EOO02834.1 - 0.089 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EOO02834.1 - 0.12 12.3 1.2 0.32 11.0 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO02834.1 - 2.8 7.6 5.1 0.45 10.2 0.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.9 EOO02835.1 - 0.0037 17.1 3.3 0.93 9.4 0.3 2.6 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme efThoc1 PF11957.3 EOO02836.1 - 4.1e-158 526.9 7.4 5.1e-158 526.6 5.1 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor WD40 PF00400.27 EOO02837.1 - 6.3e-21 73.4 0.4 5.4e-05 22.9 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EOO02837.1 - 2.4e-05 23.2 0.0 0.0046 15.7 0.0 2.9 1 1 2 3 3 3 2 Nup133 N terminal like Asp PF00026.18 EOO02838.1 - 2.1e-39 135.6 0.2 2.7e-39 135.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EOO02838.1 - 2.1e-06 27.3 0.0 4.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal zf-Tim10_DDP PF02953.10 EOO02839.1 - 4.8e-22 77.0 1.4 6.3e-22 76.6 1.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Gti1_Pac2 PF09729.4 EOO02840.1 - 2.5e-58 196.6 0.0 3.2e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family AIG2_2 PF13772.1 EOO02841.1 - 1.3e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EOO02841.1 - 0.002 18.6 0.1 0.0031 17.9 0.0 1.3 1 1 0 1 1 1 1 AIG2-like family Epimerase PF01370.16 EOO02842.1 - 1.2e-55 188.5 0.0 1.5e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EOO02842.1 - 4.2e-24 84.9 0.0 4e-23 81.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EOO02842.1 - 7.2e-22 77.3 0.0 9.7e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EOO02842.1 - 2.4e-21 75.8 0.1 1.3e-20 73.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EOO02842.1 - 2.5e-21 75.8 0.0 3.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EOO02842.1 - 5.2e-09 36.3 0.0 8.4e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EOO02842.1 - 0.0014 18.5 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EOO02842.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family Lipase3_N PF03893.11 EOO02842.1 - 0.11 12.3 0.0 27 4.6 0.0 3.0 3 0 0 3 3 3 0 Lipase 3 N-terminal region TPT PF03151.11 EOO02843.1 - 1.6e-16 60.3 15.6 1.6e-16 60.3 10.8 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EOO02843.1 - 0.0075 16.3 14.7 0.0075 16.3 10.2 3.1 2 2 1 3 3 3 1 EamA-like transporter family CMAS PF02353.15 EOO02844.1 - 2.8e-60 203.7 0.0 3.5e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EOO02844.1 - 4.1e-13 49.3 0.0 1e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO02844.1 - 8e-08 32.6 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO02844.1 - 0.00054 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO02844.1 - 0.0018 18.8 0.0 0.0062 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO02844.1 - 0.0034 17.4 0.0 0.0084 16.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO02844.1 - 0.0043 17.5 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02844.1 - 0.0045 16.5 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EOO02844.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EOO02844.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 EOO02844.1 - 0.19 11.1 0.1 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MBOAT PF03062.14 EOO02845.1 - 2.1e-45 155.2 8.6 2.1e-45 155.2 6.0 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Fork_head PF00250.13 EOO02846.1 - 1e-33 115.2 0.2 2.3e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Fork head domain tRNA-synt_2b PF00587.20 EOO02847.1 - 6.5e-68 227.6 0.1 9.9e-68 227.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EOO02847.1 - 1.5e-23 82.5 1.9 1.2e-22 79.6 0.0 3.1 3 0 0 3 3 3 1 Anticodon binding domain DUF2346 PF09803.4 EOO02847.1 - 0.071 12.9 0.6 0.24 11.2 0.4 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Ribosomal_L23eN PF03939.8 EOO02849.1 - 1.1e-20 73.3 9.7 1.1e-20 73.3 6.7 3.0 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EOO02849.1 - 8.5e-17 60.8 1.3 1.6e-16 59.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3888 PF13027.1 EOO02849.1 - 0.039 13.8 0.2 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) TGS PF02824.16 EOO02850.1 - 2.6e-18 65.6 0.0 5.8e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EOO02850.1 - 8.4e-18 64.4 0.0 2.5e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EOO02850.1 - 4.6e-09 35.7 0.0 2.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EOO02850.1 - 3.6e-05 23.2 0.1 0.55 9.6 0.0 3.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EOO02850.1 - 0.00017 21.4 0.1 0.042 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EOO02850.1 - 0.0059 15.4 0.3 0.022 13.5 0.0 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EOO02850.1 - 0.029 14.8 0.0 0.39 11.2 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 EOO02850.1 - 0.039 13.1 0.1 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family G10 PF01125.12 EOO02851.1 - 7.9e-36 122.7 0.5 9e-36 122.6 0.3 1.0 1 0 0 1 1 1 1 G10 protein SNase PF00565.12 EOO02851.1 - 0.054 13.7 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphylococcal nuclease homologue DUF1040 PF06288.8 EOO02851.1 - 0.13 12.5 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Peroxin-3 PF04882.7 EOO02852.1 - 1.5e-143 478.6 0.0 1.7e-143 478.4 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DER1 PF04511.10 EOO02853.1 - 4.8e-50 169.8 5.0 6e-50 169.4 3.4 1.0 1 0 0 1 1 1 1 Der1-like family Methyltransf_23 PF13489.1 EOO02854.1 - 2.4e-14 53.3 0.0 4.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO02854.1 - 1e-09 38.1 0.0 3.5e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO02854.1 - 1.3e-09 38.4 0.0 3.7e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO02854.1 - 6.7e-09 36.3 0.3 7.6e-08 32.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO02854.1 - 2.6e-08 34.2 0.0 7.4e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO02854.1 - 1.5e-06 27.4 0.0 2.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EOO02854.1 - 0.00067 19.9 0.0 0.0024 18.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EOO02854.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EOO02854.1 - 0.0098 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EOO02854.1 - 0.013 14.6 0.0 0.046 12.8 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family GARS_A PF01071.14 EOO02855.1 - 2.1e-84 281.9 0.7 2e-83 278.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EOO02855.1 - 1.1e-34 118.8 0.9 4.5e-34 116.9 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EOO02855.1 - 2.4e-31 108.8 0.2 1.7e-30 106.0 0.0 2.3 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EOO02855.1 - 2.7e-25 88.3 0.4 7.6e-25 86.9 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EOO02855.1 - 4.2e-16 58.9 3.2 4.2e-16 58.9 2.2 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EOO02855.1 - 5.6e-11 42.5 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EOO02855.1 - 1.3e-06 27.3 0.0 2.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EOO02855.1 - 6.8e-05 22.2 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EOO02855.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EOO02855.1 - 0.0048 16.3 0.1 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EOO02855.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Tyr-DNA_phospho PF06087.7 EOO02856.1 - 8.6e-36 123.5 0.0 1.6e-35 122.6 0.0 1.4 2 0 0 2 2 2 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EOO02856.1 - 0.0016 17.8 0.6 0.0016 17.8 0.4 2.8 3 0 0 3 3 3 1 Ubiquitin interaction motif MRP-S31 PF15433.1 EOO02856.1 - 0.0041 16.5 5.9 0.0057 16.1 4.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 SRP-alpha_N PF04086.8 EOO02856.1 - 1.2 8.4 9.5 1.7 7.9 6.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ank_2 PF12796.2 EOO02857.1 - 2.5e-23 82.2 0.0 2.3e-15 56.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EOO02857.1 - 3.6e-19 67.5 3.8 1e-07 31.4 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EOO02857.1 - 7e-14 51.5 4.8 2.4e-06 27.5 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO02857.1 - 9.3e-13 47.0 0.3 0.00035 20.5 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EOO02857.1 - 4.1e-11 43.0 0.0 0.00058 20.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) STE3 PF02076.10 EOO02858.1 - 4.3e-46 157.2 18.0 5e-46 157.0 12.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor Sarcoglycan_2 PF05510.8 EOO02858.1 - 0.0098 14.2 0.0 0.24 9.6 0.0 2.1 2 0 0 2 2 2 2 Sarcoglycan alpha/epsilon DUF2834 PF11196.3 EOO02858.1 - 0.056 13.5 0.3 0.056 13.5 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) SSB PF00436.20 EOO02859.1 - 3.6e-20 71.7 0.0 4.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HAD_2 PF13419.1 EOO02860.1 - 6e-28 98.2 0.0 7.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EOO02860.1 - 0.048 13.3 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like FA_hydroxylase PF04116.8 EOO02861.1 - 4.8e-15 55.9 26.3 1.9e-14 54.0 14.3 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily zf-U1 PF06220.7 EOO02862.1 - 0.45 10.1 3.8 5.9 6.5 0.2 2.1 2 0 0 2 2 2 0 U1 zinc finger Ldh_1_C PF02866.13 EOO02863.1 - 2.6e-45 154.2 0.0 3.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EOO02863.1 - 3.2e-42 143.6 0.1 5e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EOO02863.1 - 0.02 13.5 0.0 0.073 11.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2015 PF09435.5 EOO02864.1 - 3.1e-46 156.3 0.0 3.4e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TRAPP PF04051.11 EOO02865.1 - 3.3e-45 153.3 0.0 3.9e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L28e PF01778.12 EOO02866.1 - 2.6e-40 137.4 0.5 3.2e-40 137.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF4150 PF13665.1 EOO02866.1 - 0.12 12.2 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) DUF3328 PF11807.3 EOO02867.1 - 2.6e-48 164.5 0.0 3.1e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2423 PF10338.4 EOO02868.1 - 3.4e-19 68.5 3.8 3.4e-19 68.5 2.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Borrelia_REV PF03978.8 EOO02868.1 - 0.049 13.3 1.6 0.057 13.1 0.8 1.4 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein TP53IP5 PF15331.1 EOO02868.1 - 4.7 7.0 10.3 5.5 6.8 7.1 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF572 PF04502.8 EOO02868.1 - 4.9 6.2 14.2 5.2 6.1 9.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_hydro_16 PF00722.16 EOO02869.1 - 1.5e-43 148.2 3.7 2.4e-43 147.5 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 EOO02870.1 - 1.2e-65 221.8 6.5 1.3e-65 221.7 4.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO02870.1 - 8.9e-14 50.9 25.4 1.7e-08 33.5 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.2 EOO02870.1 - 0.88 9.4 8.8 0.23 11.3 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) zf-RING_5 PF14634.1 EOO02871.1 - 0.00011 21.8 5.7 0.00041 20.0 3.9 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EOO02871.1 - 0.0011 18.5 3.0 0.0028 17.2 2.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO02871.1 - 0.0017 18.3 0.6 0.0017 18.3 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EOO02871.1 - 0.0077 16.0 2.2 0.016 15.0 0.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EOO02871.1 - 0.015 15.0 1.4 0.019 14.7 0.2 1.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EOO02871.1 - 0.018 14.9 1.9 0.065 13.1 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EOO02871.1 - 0.019 14.5 0.4 0.019 14.5 0.3 2.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EOO02871.1 - 0.061 13.2 6.7 0.19 11.6 4.7 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.1 EOO02871.1 - 0.18 11.5 6.9 0.56 9.9 2.8 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 EOO02871.1 - 0.77 9.2 4.8 0.83 9.1 1.8 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain IBR PF01485.16 EOO02871.1 - 4.1 7.3 8.7 2.8 7.8 3.3 2.4 1 1 2 3 3 3 0 IBR domain zinc-ribbons_6 PF07191.7 EOO02871.1 - 6.9 6.5 9.2 6.9 6.5 3.7 2.6 1 1 1 2 2 2 0 zinc-ribbons ILVD_EDD PF00920.16 EOO02873.1 - 2e-195 650.1 0.7 2.3e-195 649.9 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family PhzC-PhzF PF02567.11 EOO02874.1 - 1.3e-37 129.5 0.1 2e-37 128.9 0.1 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short PF00106.20 EOO02875.1 - 2.8e-10 40.3 0.3 7.8e-08 32.4 0.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EOO02875.1 - 6.2e-05 23.0 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EOO02875.1 - 0.00087 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 KR domain LytR_C PF13399.1 EOO02875.1 - 0.13 12.7 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Prp19 PF08606.6 EOO02876.1 - 3e-33 113.3 2.1 3e-33 113.3 1.5 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EOO02876.1 - 7.9e-13 47.7 0.2 0.0074 16.1 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EOO02876.1 - 2.6e-05 24.0 0.0 0.039 13.6 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EOO02876.1 - 0.0009 18.1 0.0 0.082 11.6 0.0 2.4 1 1 0 2 2 2 1 Coatomer WD associated region zf-Nse PF11789.3 EOO02876.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PQQ_2 PF13360.1 EOO02876.1 - 0.0051 16.2 0.9 0.015 14.7 0.2 1.9 1 1 1 2 2 2 1 PQQ-like domain VID27 PF08553.5 EOO02876.1 - 0.0065 14.7 1.0 0.0091 14.2 0.0 1.6 2 0 0 2 2 2 1 VID27 cytoplasmic protein U-box PF04564.10 EOO02876.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 U-box domain Uds1 PF15456.1 EOO02876.1 - 0.013 15.5 2.1 0.023 14.6 1.5 1.3 1 0 0 1 1 1 0 Up-regulated During Septation ADIP PF11559.3 EOO02876.1 - 0.046 13.6 0.3 0.084 12.7 0.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4604 PF15377.1 EOO02877.1 - 2.2e-24 86.4 7.0 3.3e-24 85.8 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Aldo_ket_red PF00248.16 EOO02878.1 - 1.3e-47 161.9 0.0 1.8e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family OHCU_decarbox PF09349.5 EOO02879.1 - 2.3e-38 131.9 0.0 2.9e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Myb_DNA-binding PF00249.26 EOO02880.1 - 1.3e-11 44.3 0.2 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EOO02880.1 - 4e-07 30.0 0.1 0.0058 16.7 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EOO02880.1 - 0.036 13.8 0.4 0.097 12.4 0.1 1.8 1 1 1 2 2 2 0 Rap1 Myb domain MADF_DNA_bdg PF10545.4 EOO02880.1 - 0.078 13.1 0.4 13 6.0 0.0 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_transf_15 PF01793.11 EOO02881.1 - 1.6e-127 425.0 0.3 2.1e-127 424.6 0.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase eRF1_1 PF03463.10 EOO02882.1 - 1.3e-40 138.0 0.0 2.1e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EOO02882.1 - 5.5e-22 78.5 0.0 8.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EOO02882.1 - 3.6e-21 75.5 0.0 7.7e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 DUF4349 PF14257.1 EOO02882.1 - 0.026 13.7 0.1 0.054 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Peptidase_M6 PF05547.6 EOO02883.1 - 0.012 13.6 0.9 0.17 9.8 0.7 2.0 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 DUF2332 PF10094.4 EOO02884.1 - 0.14 11.0 0.2 9 5.1 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2332) COX5B PF01215.14 EOO02885.1 - 5.4e-40 136.2 0.0 7.1e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Dabb PF07876.7 EOO02886.1 - 2.7e-23 82.2 0.0 3.2e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Proteasome PF00227.21 EOO02887.1 - 1e-48 165.1 0.0 1.4e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EOO02887.1 - 1.4e-12 46.6 0.1 2.8e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EOO02887.1 - 0.32 10.5 3.6 0.16 11.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) C2 PF00168.25 EOO02888.1 - 4.9e-15 55.1 0.0 7.3e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain OB_NTP_bind PF07717.11 EOO02890.1 - 3.7e-24 84.7 0.0 8.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EOO02890.1 - 9.5e-24 83.3 0.1 9.5e-24 83.3 0.0 3.1 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EOO02890.1 - 1.2e-11 44.3 0.0 2.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EOO02890.1 - 3.1e-06 27.3 0.0 8.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EOO02890.1 - 1.7e-05 24.4 0.1 6.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EOO02890.1 - 0.00058 18.8 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EOO02890.1 - 0.048 13.4 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 EOO02890.1 - 0.058 13.6 0.3 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Con-6 PF10346.4 EOO02891.1 - 1.3e-30 104.4 3.9 1.8e-16 59.2 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 EOO02891.1 - 0.028 14.3 0.9 0.29 11.0 0.1 2.1 1 1 0 2 2 2 0 Putative toxin 52 SpoIIIAH PF12685.2 EOO02891.1 - 0.11 11.9 3.3 0.33 10.4 2.3 1.9 1 1 0 1 1 1 0 SpoIIIAH-like protein Glyco_transf_8 PF01501.15 EOO02893.1 - 9.4e-23 80.8 0.0 1.4e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 MMR_HSR1_C PF08438.5 EOO02894.1 - 2.2e-32 111.5 0.0 4.2e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EOO02894.1 - 1.9e-08 34.2 0.0 5e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2373 PF10180.4 EOO02895.1 - 5.3e-21 73.9 0.1 9.2e-21 73.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) UPF0546 PF10639.4 EOO02896.1 - 1.6e-37 127.7 0.2 2.2e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EOO02896.1 - 0.00038 20.5 2.0 0.0037 17.2 2.0 2.0 2 0 0 2 2 2 1 EamA-like transporter family DUF485 PF04341.7 EOO02896.1 - 0.064 12.9 1.5 0.58 9.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF485 EmrE PF13536.1 EOO02896.1 - 0.58 10.3 5.1 0.33 11.1 2.3 1.5 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DnaJ PF00226.26 EOO02897.1 - 4.7e-27 93.5 2.3 8.8e-27 92.6 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EOO02897.1 - 4e-16 58.6 0.0 1.2e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EOO02897.1 - 2.5e-14 53.0 17.8 4.6e-14 52.2 12.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EOO02897.1 - 0.016 14.8 8.4 0.33 10.6 0.8 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EOO02897.1 - 8.1 6.2 9.6 0.92 9.2 1.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Lar_restr_allev PF14354.1 EOO02897.1 - 8.9 6.7 8.7 14 6.0 0.3 2.9 1 1 2 3 3 3 0 Restriction alleviation protein Lar MFS_1 PF07690.11 EOO02898.1 - 2e-12 46.5 25.0 1.2e-08 34.1 5.9 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1761 PF08570.5 EOO02899.1 - 1.3e-22 80.0 2.7 1.5e-22 79.9 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) MSP1b PF03429.8 EOO02899.1 - 0.28 9.0 1.7 0.32 8.8 1.2 1.1 1 0 0 1 1 1 0 Major surface protein 1B Fungal_trans PF04082.13 EOO02900.1 - 1.3e-32 112.6 0.3 2.1e-32 112.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO02900.1 - 1e-08 34.9 14.6 1.9e-08 34.0 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EOO02901.1 - 0.00019 21.5 13.5 0.4 11.1 2.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Macoilin PF09726.4 EOO02901.1 - 0.006 14.9 1.2 0.0076 14.5 0.8 1.1 1 0 0 1 1 1 1 Transmembrane protein zf-C2H2 PF00096.21 EOO02901.1 - 0.02 15.2 15.7 0.19 12.1 2.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Atg14 PF10186.4 EOO02901.1 - 0.03 13.2 0.3 0.042 12.7 0.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EOO02901.1 - 0.043 13.6 5.8 0.08 12.7 4.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.6 EOO02901.1 - 0.045 13.6 2.5 0.08 12.8 1.7 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.3 EOO02901.1 - 0.061 12.5 6.3 0.086 12.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COG6 PF06419.6 EOO02901.1 - 0.24 9.4 2.9 0.33 9.0 2.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 APG6 PF04111.7 EOO02901.1 - 0.25 10.3 2.8 0.35 9.8 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EOO02901.1 - 0.45 10.0 4.5 0.8 9.2 3.1 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 EOO02901.1 - 0.47 10.2 6.1 0.099 12.3 0.8 2.1 1 1 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EOO02901.1 - 0.65 9.9 2.7 0.85 9.5 1.4 1.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.1 EOO02901.1 - 1.2 7.9 4.1 1.8 7.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF536 PF04394.9 EOO02901.1 - 1.4 8.7 8.3 2.1 8.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Adenylsucc_synt PF00709.16 EOO02902.1 - 5.3e-27 94.5 0.0 6.3e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase UTP15_C PF09384.5 EOO02903.1 - 5.7e-43 146.1 0.0 6.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 UTP15 C terminal DUF3438 PF11920.3 EOO02904.1 - 0.078 11.8 0.7 0.11 11.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) ATG2_CAD PF13329.1 EOO02905.1 - 1.1e-50 171.3 0.6 3.1e-50 169.8 0.4 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EOO02905.1 - 1.2e-31 108.7 1.9 2.6e-31 107.6 0.3 2.5 3 0 0 3 3 3 1 ATG C terminal domain FAD_binding_3 PF01494.14 EOO02906.1 - 1.9e-05 23.9 0.1 2.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain SIS PF01380.17 EOO02907.1 - 1.6e-11 43.9 0.0 3.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EOO02907.1 - 0.00017 21.3 0.1 0.0005 19.8 0.1 1.8 1 1 1 2 2 2 1 SIS domain Translin PF01997.11 EOO02908.1 - 1.1e-39 136.1 1.3 2.7e-38 131.5 0.9 2.0 1 1 0 1 1 1 1 Translin family Ribosomal_L22e PF01776.12 EOO02909.1 - 5e-46 155.3 0.2 9.5e-46 154.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L22e protein family GDPD PF03009.12 EOO02909.1 - 2.1e-11 43.8 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EOO02909.1 - 0.0016 18.5 3.0 0.0072 16.4 2.1 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PIG-F PF06699.6 EOO02910.1 - 2.8e-56 190.4 5.8 3.5e-56 190.1 4.0 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2298 PF10060.4 EOO02910.1 - 0.0059 15.5 1.6 0.0081 15.0 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) Oxidored_q3 PF00499.15 EOO02910.1 - 0.0072 16.1 0.4 0.014 15.1 0.3 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ABC2_membrane PF01061.19 EOO02910.1 - 0.041 13.0 4.6 0.022 13.9 1.5 1.8 2 1 0 2 2 2 0 ABC-2 type transporter Bacteriocin_IIc PF10439.4 EOO02910.1 - 1.2 9.2 10.7 0.32 11.1 1.6 2.7 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide DUF2062 PF09835.4 EOO02910.1 - 4.4 6.8 13.0 1.8 8.1 5.5 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF3169 PF11368.3 EOO02910.1 - 4.6 6.3 5.3 2.9 7.0 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) Ribosomal_L7Ae PF01248.21 EOO02911.1 - 5e-20 70.8 0.3 4.1e-19 67.8 0.2 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SGT1 PF07093.6 EOO02911.1 - 0.23 9.8 9.3 0.45 8.8 6.5 1.5 1 1 0 1 1 1 0 SGT1 protein FHIPEP PF00771.15 EOO02911.1 - 0.81 7.9 3.8 2.1 6.5 2.3 1.8 1 1 0 1 1 1 0 FHIPEP family Mito_carr PF00153.22 EOO02912.1 - 1.3e-54 181.8 0.5 1.5e-19 69.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Reo_sigmaC PF04582.7 EOO02913.1 - 0.02 14.0 12.9 0.57 9.3 1.6 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4366 PF14283.1 EOO02914.1 - 0.0014 18.1 1.5 0.58 9.5 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4366) DUF3824 PF12868.2 EOO02914.1 - 0.0032 18.4 11.0 0.0032 18.4 7.7 13.3 3 3 11 14 14 14 3 Domain of unknwon function (DUF3824) WD40 PF00400.27 EOO02915.1 - 1.1e-55 183.5 15.6 5.3e-09 35.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EOO02915.1 - 4.9e-12 45.3 0.2 1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EOO02915.1 - 5.9e-11 41.7 0.5 3.2e-10 39.4 0.2 2.3 2 1 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 EOO02915.1 - 0.00034 20.1 1.0 1.1 8.6 0.0 3.1 1 1 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 EOO02915.1 - 0.0012 17.0 7.7 2 6.4 0.8 5.2 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EOO02915.1 - 0.0026 16.5 2.0 4.1 6.0 0.4 4.7 3 2 2 5 5 5 1 Nup133 N terminal like PRANC PF09372.5 EOO02915.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain CPSF_A PF03178.10 EOO02915.1 - 0.13 11.3 0.0 1.4 7.9 0.0 2.4 3 0 0 3 3 3 0 CPSF A subunit region Podoplanin PF05808.6 EOO02916.1 - 0.0021 17.6 1.8 0.0045 16.5 1.2 1.5 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 EOO02916.1 - 0.0079 15.4 0.5 0.0079 15.4 0.4 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.6 EOO02916.1 - 0.0096 13.8 4.8 0.013 13.3 3.3 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Mid2 PF04478.7 EOO02916.1 - 0.015 14.7 0.5 0.029 13.7 0.2 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 EOO02916.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EOO02916.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Mid1 PF12929.2 EOO02917.1 - 3.2e-127 424.7 9.4 3.7e-127 424.6 6.5 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EOO02917.1 - 0.0032 17.8 4.1 0.026 14.8 0.8 2.4 2 0 0 2 2 2 1 Fz domain HP_OMP PF01856.12 EOO02917.1 - 0.017 14.9 2.1 0.078 12.7 0.0 2.2 2 0 0 2 2 2 0 Helicobacter outer membrane protein PS_Dcarbxylase PF02666.10 EOO02918.1 - 6.7e-83 276.9 0.0 9.9e-82 273.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF4202 PF13875.1 EOO02919.1 - 1.2e-59 201.0 0.8 1.1e-58 197.9 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) DUF1793 PF08760.6 EOO02921.1 - 9.1e-79 263.2 1.1 3.1e-78 261.5 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Glyco_transf_8 PF01501.15 EOO02923.1 - 2.7e-37 128.4 0.0 5.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EOO02923.1 - 0.097 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PepX_C PF08530.5 EOO02924.1 - 6e-42 143.9 0.3 9.6e-42 143.3 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EOO02924.1 - 9.3e-38 130.1 0.0 1.3e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EOO02924.1 - 4.8e-05 23.3 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02924.1 - 0.00044 20.0 0.0 0.002 17.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cation_efflux PF01545.16 EOO02925.1 - 4.9e-25 88.1 16.9 2.9e-24 85.6 11.7 1.8 1 1 0 1 1 1 1 Cation efflux family DUF4133 PF13571.1 EOO02925.1 - 3.6 7.8 5.6 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Med5 PF08689.5 EOO02926.1 - 3.1e-15 55.0 0.0 3.5e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 PsbW PF07123.7 EOO02926.1 - 0.0017 18.3 0.5 0.0025 17.8 0.3 1.3 1 0 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) Frag1 PF10277.4 EOO02927.1 - 1.1e-42 145.9 13.2 1.3e-42 145.6 9.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Zn_peptidase_2 PF04298.7 EOO02927.1 - 0.2 10.9 1.4 9.8 5.4 0.0 2.9 1 1 1 3 3 3 0 Putative neutral zinc metallopeptidase DUF3611 PF12263.3 EOO02927.1 - 0.81 9.0 10.6 0.34 10.2 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF3812 PF12757.2 EOO02928.1 - 3e-40 137.1 13.5 3e-40 137.1 9.4 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF3812) MbeD_MobD PF04899.7 EOO02929.1 - 0.054 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like IncA PF04156.9 EOO02929.1 - 0.13 11.8 4.8 0.27 10.8 3.3 1.5 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EOO02929.1 - 0.15 11.5 5.1 0.57 9.7 3.5 1.9 1 0 0 1 1 1 0 Septum formation initiator CENP-Q PF13094.1 EOO02929.1 - 0.41 10.6 10.7 0.13 12.2 4.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ax_dynein_light PF10211.4 EOO02929.1 - 0.82 9.4 7.3 1.8 8.3 5.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Mito_carr PF00153.22 EOO02930.1 - 1.8e-71 235.9 0.9 1.3e-25 88.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EOO02930.1 - 5.8e-19 65.8 5.4 3.4e-07 29.0 0.1 5.7 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 EOO02930.1 - 7.5e-18 62.7 0.7 1.8e-06 27.3 0.1 5.9 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EOO02930.1 - 3.6e-17 62.2 3.0 5e-08 32.9 0.2 3.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EOO02930.1 - 2.1e-14 52.0 2.6 7.8e-06 25.0 0.2 4.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EOO02930.1 - 2.4e-14 52.6 3.0 0.003 17.1 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain pair SMAP PF15477.1 EOO02931.1 - 8.3e-16 58.0 4.7 8.3e-16 58.0 3.2 5.7 3 2 0 3 3 3 1 Small acidic protein family Sec10 PF07393.6 EOO02932.1 - 4.8e-170 567.1 0.0 5.9e-170 566.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EOO02932.1 - 2.4e-07 30.3 0.2 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EOO02932.1 - 3.8e-06 26.4 0.1 9e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Vps53_N PF04100.7 EOO02932.1 - 0.036 12.8 0.3 0.07 11.8 0.2 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal adh_short PF00106.20 EOO02933.1 - 1.9e-29 102.7 0.7 2.2e-29 102.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO02933.1 - 5e-16 59.2 0.0 1.3e-11 44.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO02933.1 - 5.5e-12 45.7 0.4 7.6e-12 45.2 0.3 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EOO02933.1 - 0.01 15.7 0.4 0.017 14.9 0.2 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2334 PF10096.4 EOO02933.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) LA-virus_coat PF09220.5 EOO02933.1 - 0.053 11.9 0.0 0.074 11.4 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein STAG PF08514.6 EOO02934.1 - 1.1e-28 99.3 0.5 4.5e-28 97.3 0.4 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EOO02934.1 - 2.1e-05 24.6 0.0 0.0013 18.9 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats Nipped-B_C PF12830.2 EOO02934.1 - 0.08 12.5 0.6 2.4 7.7 0.0 3.3 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus Med5 PF08689.5 EOO02935.1 - 5.2e-37 127.1 0.0 6.7e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SSF PF00474.12 EOO02935.1 - 0.0016 17.1 0.1 0.0026 16.4 0.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Cation_efflux PF01545.16 EOO02936.1 - 7.1e-28 97.4 9.0 9e-28 97.1 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family PAS_9 PF13426.1 EOO02937.1 - 4.8e-17 62.2 0.0 2.6e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EOO02937.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EOO02937.1 - 0.082 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 PAS fold SAP PF02037.22 EOO02938.1 - 4.3e-14 51.6 0.1 7.8e-14 50.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EOO02938.1 - 0.09 12.3 1.4 0.16 11.5 0.0 2.2 2 1 0 2 2 2 0 HeH/LEM domain CDC27 PF09507.5 EOO02938.1 - 4.4 6.4 14.8 5.6 6.0 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HEAT PF02985.17 EOO02939.1 - 3.3e-27 92.0 6.1 0.00017 21.4 0.0 9.9 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EOO02939.1 - 8.1e-25 86.6 14.6 7.6e-14 51.7 0.0 10.5 8 2 5 13 13 12 6 HEAT-like repeat HEAT_2 PF13646.1 EOO02939.1 - 6.8e-22 77.5 2.1 3.9e-07 30.2 0.0 8.0 3 3 6 9 9 9 6 HEAT repeats MMS19_C PF12460.3 EOO02939.1 - 2.8e-10 39.5 0.0 0.016 13.9 0.0 4.3 4 0 0 4 4 4 3 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 EOO02939.1 - 2.1e-06 27.6 0.3 6.3 6.6 0.1 6.4 5 2 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EOO02939.1 - 2.2e-06 27.4 0.1 0.00014 21.7 0.1 4.0 4 1 0 4 4 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EOO02939.1 - 3.4e-06 27.3 0.0 0.52 10.7 0.0 5.9 6 1 2 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EOO02939.1 - 7.6e-05 22.1 0.0 3 7.1 0.0 5.5 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.18 EOO02939.1 - 0.00026 20.6 6.1 0.078 12.8 0.0 5.7 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 EOO02939.1 - 0.15 11.0 0.3 13 4.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 EOO02939.1 - 0.21 12.1 3.8 44 4.9 0.0 5.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Amidohydro_1 PF01979.15 EOO02941.1 - 2.3e-40 139.2 4.1 2.7e-40 139.0 2.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EOO02941.1 - 2.8e-14 53.8 3.3 4.4e-14 53.1 2.3 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EOO02941.1 - 1e-11 44.7 0.1 1.3e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.17 EOO02941.1 - 0.0023 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 EOO02942.1 - 8.9e-57 192.3 28.9 5e-56 189.8 20.1 1.9 1 1 0 1 1 1 1 Permease family GATase_4 PF13230.1 EOO02943.1 - 3.3e-18 65.3 0.0 1.9e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EOO02943.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EOO02943.1 - 2.8e-06 26.2 0.0 0.00021 20.0 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Bac_rhamnosid PF05592.6 EOO02944.1 - 1.8e-16 59.5 0.2 4.9e-14 51.4 0.1 2.9 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EOO02944.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF608 F-box-like PF12937.2 EOO02948.1 - 0.024 14.3 0.3 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 F-box-like Cytochrom_B_N PF00033.14 EOO02949.1 - 0.038 13.3 0.3 0.038 13.3 0.2 1.8 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EOO02949.1 - 0.042 13.2 2.0 0.11 11.8 1.4 1.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PIG-Y PF15159.1 EOO02949.1 - 2.5 8.3 9.5 10 6.4 6.6 1.9 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y MFS_1 PF07690.11 EOO02950.1 - 7.7e-13 47.8 16.6 7.7e-13 47.8 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EOO02950.1 - 0.0095 14.7 5.9 0.01 14.6 3.1 1.6 1 1 1 2 2 2 1 Nucleoside H+ symporter PetG PF02529.10 EOO02950.1 - 1.4 8.5 7.0 0.14 11.7 0.9 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Mito_carr PF00153.22 EOO02951.1 - 1.9e-42 142.8 10.5 8.1e-17 60.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EOO02952.1 - 2.1e-21 75.3 0.0 3e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO02952.1 - 6.5e-16 58.0 0.0 9.5e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO02952.1 - 5.1e-12 45.4 0.0 7.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TB2_DP1_HVA22 PF03134.14 EOO02953.1 - 4.4e-32 109.6 6.3 6.8e-32 109.0 4.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.16 EOO02953.1 - 0.41 9.5 8.9 1.2 7.9 6.2 1.7 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Kei1 PF08552.6 EOO02953.1 - 0.44 10.1 6.0 0.94 9.1 3.5 1.9 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 UreD PF01774.12 EOO02954.1 - 6.3e-57 192.4 0.1 7.6e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Cyclin_N PF00134.18 EOO02955.1 - 3.1e-43 146.3 0.2 7.9e-43 145.0 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EOO02955.1 - 2.4e-20 72.6 0.1 2e-19 69.6 0.1 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain MarR_2 PF12802.2 EOO02956.1 - 0.057 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 MarR family GldM_N PF12081.3 EOO02956.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain FAD_binding_3 PF01494.14 EOO02957.1 - 5.9e-13 48.5 0.0 1e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO02957.1 - 8e-13 48.0 2.6 5.1e-08 32.1 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EOO02957.1 - 4.2e-07 29.2 0.5 2.1e-06 26.9 0.3 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EOO02957.1 - 4.5e-05 22.1 0.9 0.0006 18.4 0.6 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EOO02957.1 - 5.7e-05 23.0 0.0 0.00026 20.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO02957.1 - 0.00028 19.8 0.5 0.0005 19.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EOO02957.1 - 0.0004 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO02957.1 - 0.0015 18.5 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EOO02957.1 - 0.0018 18.6 0.8 0.069 13.5 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EOO02957.1 - 0.0094 15.0 0.5 0.36 9.8 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EOO02957.1 - 0.061 12.1 0.6 0.15 10.8 0.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Cupin_8 PF13621.1 EOO02958.1 - 3.3e-65 220.0 0.0 4.3e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EOO02958.1 - 1.9e-07 30.6 0.2 0.00078 18.7 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EOO02958.1 - 0.04 14.1 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase GST_N_3 PF13417.1 EOO02959.1 - 8.7e-13 48.3 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EOO02959.1 - 2.5e-12 46.5 0.0 5.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EOO02959.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EOO02959.1 - 4.3e-10 39.6 0.0 8.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EOO02959.1 - 2.1e-09 37.1 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EOO02959.1 - 1.6e-07 31.7 0.0 2.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2838 PF10998.3 EOO02960.1 - 1.3e-46 157.0 12.4 1.3e-46 157.0 8.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.13 EOO02960.1 - 0.011 15.2 1.6 0.03 13.8 0.5 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EOO02960.1 - 0.053 13.1 2.1 0.12 12.0 1.4 1.5 1 0 0 1 1 1 0 IncA protein ApoLp-III PF07464.6 EOO02960.1 - 0.073 13.0 1.9 0.12 12.3 1.3 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PhoU_div PF01865.11 EOO02960.1 - 0.15 11.2 0.2 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 Not3 PF04065.10 EOO02960.1 - 0.17 11.0 3.4 0.28 10.4 2.4 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Val_tRNA-synt_C PF10458.4 EOO02960.1 - 0.47 10.5 4.7 14 5.8 2.1 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3584 PF12128.3 EOO02960.1 - 0.86 6.8 4.7 1.2 6.3 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LigB PF02900.13 EOO02961.1 - 2e-17 63.1 1.8 2.6e-17 62.6 0.2 1.7 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase ADH_zinc_N_2 PF13602.1 EOO02962.1 - 5.5e-23 82.2 0.0 1.2e-22 81.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO02962.1 - 3.4e-14 52.4 0.1 5.5e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EOO02963.1 - 1.3e-14 54.4 1.7 1.8e-14 53.9 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO02963.1 - 6.8e-06 25.8 1.8 1.3e-05 24.9 1.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO02963.1 - 6.2e-05 22.8 0.0 8.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_18 PF12847.2 EOO02963.1 - 0.0047 17.4 0.0 0.02 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Metallophos PF00149.23 EOO02964.1 - 5.3e-13 48.8 2.6 1.7e-12 47.1 1.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 EOO02965.1 - 1.3e-23 83.7 6.3 5.7e-23 81.6 3.2 2.7 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO02965.1 - 7.6e-22 78.2 0.1 1.8e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.2 EOO02965.1 - 1.3e-16 61.1 2.8 2.7e-16 60.1 0.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family KR PF08659.5 EOO02965.1 - 1.2e-11 44.6 3.9 1.9e-11 43.9 1.4 2.1 3 0 0 3 3 3 1 KR domain Abhydrolase_5 PF12695.2 EOO02965.1 - 0.00017 21.3 0.2 0.00032 20.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EOO02965.1 - 0.0012 18.1 0.0 0.094 11.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family RAMP4 PF06624.7 EOO02966.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 YqzE PF14038.1 EOO02966.1 - 1.6 8.5 4.0 2.2 8.0 0.9 2.4 2 1 0 2 2 2 0 YqzE-like protein Abhydrolase_3 PF07859.8 EOO02967.1 - 9.5e-05 22.0 0.2 0.0018 17.8 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO02967.1 - 0.007 16.1 0.5 0.012 15.3 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO02967.1 - 0.015 15.2 1.5 0.023 14.5 1.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EOO02968.1 - 3.4e-16 59.3 0.0 6.7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EOO02968.1 - 3.7e-16 59.6 0.0 6.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal BBE PF08031.7 EOO02968.1 - 0.064 13.1 0.0 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Berberine and berberine like Arm PF00514.18 EOO02969.1 - 1e-94 307.4 15.3 2.8e-13 49.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EOO02969.1 - 9.8e-26 89.8 0.2 5.1e-10 39.5 0.0 5.9 1 1 5 6 6 6 6 HEAT repeats IBB PF01749.15 EOO02969.1 - 1.4e-22 79.6 1.7 2.3e-22 78.9 1.2 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EOO02969.1 - 4.1e-22 78.0 12.2 1.1e-09 38.4 0.1 6.3 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EOO02969.1 - 7.4e-21 72.3 2.2 4.7e-06 26.2 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 EOO02969.1 - 1e-10 41.1 0.0 0.0058 15.7 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EOO02969.1 - 1.5e-05 23.5 0.0 0.0014 16.9 0.0 2.7 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EOO02969.1 - 0.00012 21.9 0.0 0.97 9.3 0.0 4.6 2 1 4 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 EOO02969.1 - 0.00033 20.8 0.4 0.66 10.6 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EOO02969.1 - 0.0014 16.9 0.1 0.56 8.4 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 EOO02969.1 - 0.023 14.2 0.0 18 5.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain TRAP_alpha PF03896.11 EOO02970.1 - 8.7e-05 21.6 0.1 0.00014 20.9 0.0 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Sema PF01403.14 EOO02970.1 - 0.067 11.6 0.0 0.091 11.2 0.0 1.1 1 0 0 1 1 1 0 Sema domain Pkinase PF00069.20 EOO02971.1 - 1.1e-67 227.9 0.0 1.3e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO02971.1 - 1.8e-36 125.5 0.0 2.7e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO02971.1 - 0.00023 20.2 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EOO02971.1 - 0.064 12.9 0.1 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CK2S PF15011.1 EOO02972.1 - 0.038 13.7 0.1 0.39 10.4 0.0 2.3 3 0 0 3 3 3 0 Casein Kinase 2 substrate GCD14 PF08704.5 EOO02972.1 - 0.068 12.6 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Peptidase_M14 PF00246.19 EOO02973.1 - 1.4e-67 228.2 0.0 1.9e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase POT1 PF02765.12 EOO02974.1 - 1.4e-10 41.2 0.0 3.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EOO02974.1 - 0.0071 16.1 0.0 0.7 9.7 0.0 3.3 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain MADF_DNA_bdg PF10545.4 EOO02975.1 - 0.099 12.8 0.1 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Tom37_C PF11801.3 EOO02975.1 - 0.29 10.9 4.6 0.16 11.7 0.3 2.4 2 1 1 3 3 3 0 Tom37 C-terminal domain Fungal_trans_2 PF11951.3 EOO02976.1 - 4.4e-08 32.1 1.1 5e-08 31.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO02976.1 - 7.8e-06 25.6 5.3 1.3e-05 24.9 3.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 EOO02977.1 - 8e-10 37.9 0.0 4.8e-06 25.5 0.0 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EOO02977.1 - 5.6e-09 35.6 11.9 1e-08 34.8 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EOO02977.1 - 2.1e-08 33.7 9.1 3.8e-08 32.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EOO02977.1 - 6.6e-08 32.4 11.2 1.3e-07 31.4 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EOO02977.1 - 1.9e-07 30.5 10.2 3.5e-07 29.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EOO02977.1 - 8.3e-06 25.4 10.7 1.5e-05 24.5 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EOO02977.1 - 3e-05 24.0 7.8 7.6e-05 22.7 5.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EOO02977.1 - 4.5e-05 22.9 4.5 0.00011 21.7 3.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 EOO02977.1 - 0.0037 17.0 1.1 0.0085 15.8 0.7 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Helicase_C PF00271.26 EOO02977.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EOO02977.1 - 0.0055 16.3 5.1 0.03 14.0 3.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EOO02977.1 - 0.01 15.7 9.6 0.019 14.7 6.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EOO02977.1 - 0.34 10.5 7.8 0.14 11.7 3.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EOO02977.1 - 0.72 9.3 5.5 1.8 8.0 3.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-Apc11 PF12861.2 EOO02977.1 - 1.3 8.9 7.1 3.2 7.6 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FMN_dh PF01070.13 EOO02978.1 - 1.4e-86 290.5 0.0 1.7e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EOO02978.1 - 9.5e-06 24.7 0.3 3.1e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EOO02978.1 - 8.4e-05 21.8 0.3 0.00016 20.9 0.1 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EOO02978.1 - 0.00016 20.8 0.1 0.011 14.7 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EOO02978.1 - 0.00036 19.5 0.2 0.0028 16.5 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain zf-HC2 PF13490.1 EOO02978.1 - 0.00079 19.3 0.0 4.1 7.4 0.0 3.9 4 0 0 4 4 4 1 Putative zinc-finger DHO_dh PF01180.16 EOO02978.1 - 0.008 15.1 0.5 0.65 8.8 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EOO02978.1 - 0.044 13.0 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein WD40 PF00400.27 EOO02979.1 - 3.7e-31 105.8 4.5 2.6e-07 30.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EOO02979.1 - 1.8e-06 27.8 0.1 0.0011 18.7 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3425 PF11905.3 EOO02979.1 - 0.066 13.1 0.1 0.58 10.0 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) Dynamin_N PF00350.18 EOO02980.1 - 4.3e-44 150.2 0.0 9.7e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EOO02980.1 - 3.4e-11 42.4 0.6 1.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region Miro PF08477.8 EOO02980.1 - 0.0051 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO02980.1 - 0.01 15.8 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_M4_C PF02868.10 EOO02980.1 - 0.08 12.6 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain AAA_16 PF13191.1 EOO02980.1 - 0.83 9.6 5.2 0.64 9.9 0.0 2.9 3 1 1 4 4 4 0 AAA ATPase domain PQ-loop PF04193.9 EOO02981.1 - 7.6e-32 108.6 16.5 3e-17 61.9 0.7 3.0 3 0 0 3 3 3 2 PQ loop repeat MtrF PF09472.5 EOO02981.1 - 0.035 13.3 0.2 1.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PLDc_N PF13396.1 EOO02981.1 - 0.76 9.5 10.9 2.8 7.6 0.2 3.8 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal AT_hook PF02178.14 EOO02982.1 - 1.4 8.8 46.6 0.26 11.0 1.2 5.4 4 1 1 5 5 5 0 AT hook motif RFX_DNA_binding PF02257.10 EOO02983.1 - 2.3e-29 101.3 0.1 4.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain HA2 PF04408.18 EOO02984.1 - 2.9e-20 72.1 0.1 1.1e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EOO02984.1 - 6.5e-14 51.5 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EOO02984.1 - 2.8e-11 43.2 0.0 6.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EOO02984.1 - 2.5e-10 40.1 0.7 1.4e-09 37.6 0.2 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 EOO02984.1 - 2.9e-08 33.6 0.8 6.7e-08 32.4 0.6 1.7 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 EOO02984.1 - 1.2e-05 25.5 0.2 2.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EOO02984.1 - 0.0031 17.3 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EOO02984.1 - 0.0064 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EOO02984.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 KaiC DND1_DSRM PF14709.1 EOO02984.1 - 0.016 15.4 0.4 0.046 14.0 0.0 2.0 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 PhoH PF02562.11 EOO02984.1 - 0.027 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EOO02984.1 - 0.028 13.3 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EOO02984.1 - 0.038 14.3 0.1 0.038 14.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Zot PF05707.7 EOO02984.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ERM PF00769.14 EOO02985.1 - 0.083 12.4 8.2 0.15 11.5 5.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EOO02985.1 - 0.4 10.5 4.0 0.67 9.8 2.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pex14_N PF04695.8 EOO02985.1 - 2.6 8.1 11.8 0.13 12.3 0.5 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPRY PF00622.23 EOO02986.1 - 2.9e-18 66.1 0.0 4.3e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Hydrolase_4 PF12146.3 EOO02987.1 - 1.4e-20 72.8 0.0 2.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EOO02987.1 - 1.6e-17 64.1 0.2 2.4e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO02987.1 - 1.1e-16 60.8 0.0 1.9e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO02987.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EOO02987.1 - 0.0021 17.3 0.2 0.47 9.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.5 EOO02987.1 - 0.059 12.2 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EOO02987.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpc4 PF05132.9 EOO02988.1 - 1.3e-23 83.4 0.1 3.3e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase III RPC4 Serglycin PF04360.7 EOO02988.1 - 0.23 11.1 2.2 0.46 10.2 1.2 1.7 2 0 0 2 2 2 0 Serglycin SMC_N PF02463.14 EOO02989.1 - 1.9e-48 164.5 38.5 6e-47 159.6 26.7 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EOO02989.1 - 4.8e-26 91.0 0.0 2.8e-25 88.6 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EOO02989.1 - 5.2e-10 39.7 11.7 6.7e-05 22.9 0.1 3.7 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EOO02989.1 - 1.4e-08 34.1 0.0 2.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EOO02989.1 - 8.1e-07 29.5 40.1 8.1e-07 29.5 27.8 6.7 2 2 1 4 4 2 1 AAA domain Reo_sigmaC PF04582.7 EOO02989.1 - 0.00046 19.4 21.3 0.66 9.0 2.5 5.3 3 2 1 5 5 5 3 Reovirus sigma C capsid protein ADIP PF11559.3 EOO02989.1 - 0.0023 17.8 7.6 0.0023 17.8 5.3 9.7 4 4 6 10 10 10 2 Afadin- and alpha -actinin-Binding DUF3552 PF12072.3 EOO02989.1 - 0.0053 15.9 9.1 0.0053 15.9 6.3 7.0 4 1 3 7 7 5 1 Domain of unknown function (DUF3552) SbcCD_C PF13558.1 EOO02989.1 - 0.0058 16.5 0.0 0.033 14.0 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Spc7 PF08317.6 EOO02989.1 - 0.062 11.9 121.2 0.049 12.3 9.2 7.3 3 2 4 7 7 7 0 Spc7 kinetochore protein DUF3584 PF12128.3 EOO02989.1 - 0.39 7.9 128.9 0.022 12.1 41.8 4.4 3 2 1 4 4 4 0 Protein of unknown function (DUF3584) ABC_tran PF00005.22 EOO02989.1 - 0.6 10.4 0.0 0.6 10.4 0.0 7.0 5 3 0 5 5 3 0 ABC transporter WEMBL PF05701.6 EOO02989.1 - 3.2 6.0 126.5 1.9 6.8 21.0 5.3 4 1 1 5 5 5 0 Weak chloroplast movement under blue light AAA_22 PF13401.1 EOO02989.1 - 5 7.2 11.5 10 6.2 0.0 5.2 4 1 0 4 4 4 0 AAA domain Y_phosphatase3 PF13350.1 EOO02993.1 - 3.3e-29 102.2 0.1 1.2e-15 58.1 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EOO02993.1 - 1e-07 31.9 1.2 1.9e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EOO02993.1 - 2.8e-06 26.8 0.0 8.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EOO02993.1 - 0.00088 18.8 0.0 0.04 13.5 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EOO02993.1 - 0.0022 16.8 0.1 0.018 13.8 0.0 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EOO02993.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zn_clus PF00172.13 EOO02994.1 - 0.001 18.9 12.5 0.0018 18.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EOO02994.1 - 0.0016 17.5 0.2 0.0086 15.2 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ DcpS_C PF11969.3 EOO02995.1 - 4.3e-16 59.1 8.3 1e-14 54.7 5.7 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EOO02995.1 - 2e-14 53.8 3.2 7e-14 52.1 2.2 1.9 1 1 0 1 1 1 1 HIT domain Aldedh PF00171.17 EOO02996.1 - 0.015 13.6 0.1 0.034 12.4 0.0 1.7 1 1 0 1 1 1 0 Aldehyde dehydrogenase family Acetyltransf_1 PF00583.19 EOO02997.1 - 3.9e-19 68.4 0.0 5.3e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EOO02997.1 - 1.4e-09 37.9 0.1 2.9e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EOO02997.1 - 2.5e-07 30.3 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EOO02997.1 - 4.7e-06 26.6 0.1 1.3e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EOO02997.1 - 8.2e-06 25.9 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EOO02997.1 - 1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO02997.1 - 2e-05 24.5 0.1 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain N2227 PF07942.7 EOO02998.1 - 7e-103 343.2 0.0 8.4e-103 343.0 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EOO02998.1 - 2.1e-07 30.8 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO02998.1 - 0.00023 21.5 0.0 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO02998.1 - 0.0012 19.2 0.0 0.0044 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO02998.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M20 PF01546.23 EOO02999.1 - 2.8e-18 66.1 0.0 3.4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EOO02999.1 - 3.9e-12 45.9 0.1 8.3e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain NAD_binding_4 PF07993.7 EOO03000.1 - 1.4e-31 109.3 0.0 2.1e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EOO03000.1 - 2.2e-11 43.6 0.0 4.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EOO03000.1 - 6.4e-05 23.1 0.0 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EOO03000.1 - 0.025 14.5 0.1 0.088 12.7 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EOO03000.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EOO03000.1 - 0.22 10.4 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 EOO03001.1 - 2.7e-75 253.6 12.6 2.7e-75 253.6 8.8 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03001.1 - 1.1e-16 60.4 20.6 1.1e-16 60.4 14.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily KR PF08659.5 EOO03002.1 - 4.1e-58 196.0 0.4 4.1e-58 196.0 0.3 2.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EOO03002.1 - 1.8e-55 188.4 0.0 1.2e-54 185.8 0.1 2.3 2 1 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 EOO03002.1 - 3.8e-47 160.2 0.3 3.8e-47 160.2 0.2 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EOO03002.1 - 1.2e-44 152.6 0.1 2.4e-44 151.6 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EOO03002.1 - 1.2e-33 115.5 0.1 3.8e-33 113.8 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EOO03002.1 - 1.3e-26 93.6 0.1 3.8e-23 82.2 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EOO03002.1 - 1.1e-17 63.7 0.0 4.5e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03002.1 - 8.1e-14 52.6 0.0 9.9e-13 49.0 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EOO03002.1 - 2.2e-06 27.8 0.1 5.7e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EOO03002.1 - 1.7e-05 24.4 0.4 3.6e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EOO03002.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EOO03002.1 - 0.33 9.8 0.0 0.58 9.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 EOO03003.1 - 2.2e-62 211.1 17.0 2.7e-62 210.8 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03003.1 - 3e-19 68.9 18.8 2e-10 39.9 3.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C12 PF01088.16 EOO03004.1 - 1.3e-62 210.7 0.0 1.5e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Phage_30_8 PF06019.6 EOO03004.1 - 0.071 12.8 0.1 6.5 6.4 0.1 2.1 2 0 0 2 2 2 0 Phage GP30.8 protein CN_hydrolase PF00795.17 EOO03005.1 - 1.2e-32 112.7 0.0 1.6e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_43 PF04616.9 EOO03006.1 - 6.3e-54 182.9 4.7 1e-53 182.3 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SGL PF08450.7 EOO03007.1 - 0.047 13.0 0.2 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Glyco_hydro_2_C PF02836.12 EOO03008.1 - 1.1e-93 313.4 0.2 1.3e-93 313.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EOO03008.1 - 1.6e-13 51.0 0.2 3.7e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EOO03008.1 - 0.0069 15.9 0.1 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain NAD_binding_6 PF08030.7 EOO03009.1 - 2.2e-31 108.8 0.0 3.7e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EOO03009.1 - 3.2e-21 75.1 0.0 1e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EOO03009.1 - 3.1e-16 59.6 17.2 1e-15 57.9 7.6 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EOO03009.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Carn_acyltransf PF00755.15 EOO03010.1 - 4.9e-73 246.1 0.0 6.7e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase KR PF08659.5 EOO03010.1 - 3e-49 167.1 0.3 7.3e-49 165.8 0.2 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EOO03010.1 - 1e-40 139.4 1.6 2.2e-40 138.3 1.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03010.1 - 7.8e-13 49.4 0.0 6.4e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO03010.1 - 7.6e-11 41.6 0.0 2.2e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EOO03010.1 - 8.2e-08 32.4 0.8 3.4e-07 30.4 0.6 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EOO03010.1 - 0.00024 19.9 0.3 0.0076 14.9 0.1 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EOO03010.1 - 0.0035 17.2 0.2 0.009 15.8 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 EOO03010.1 - 0.012 15.0 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_pol3_delt_C PF14840.1 EOO03010.1 - 0.068 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Abhydrolase_6 PF12697.2 EOO03011.1 - 9.9e-27 94.2 1.9 1.1e-26 94.1 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO03011.1 - 5.3e-09 35.9 0.4 2.4e-08 33.8 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family WSC PF01822.14 EOO03011.1 - 3.3e-06 26.9 10.6 7.2e-06 25.8 7.3 1.6 1 0 0 1 1 1 1 WSC domain Abhydrolase_1 PF00561.15 EOO03011.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold XPG_N PF00752.12 EOO03012.1 - 8.5e-31 106.2 0.0 2.5e-30 104.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EOO03012.1 - 4e-29 100.4 0.8 8.8e-29 99.4 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EOO03012.1 - 1.5e-05 25.1 0.8 7.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.10 EOO03012.1 - 0.062 12.9 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain HXXSHH PF07586.6 EOO03012.1 - 1.5 7.7 4.9 2.3 7.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Pkinase_Tyr PF07714.12 EOO03013.1 - 0.0001 21.5 0.0 0.0032 16.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EOO03013.1 - 0.011 14.9 0.0 0.095 11.8 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain MFS_1 PF07690.11 EOO03014.1 - 7.7e-29 100.5 21.5 9.4e-29 100.2 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 EOO03015.1 - 2.3e-16 60.1 0.1 3e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03015.1 - 6.3e-08 32.4 0.1 8.5e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO03015.1 - 3.2e-07 30.3 0.0 4.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EOO03015.1 - 1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO03015.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding UQ_con PF00179.21 EOO03016.1 - 1.3e-41 141.2 0.0 3.6e-41 139.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO03016.1 - 5.9e-05 22.8 0.0 6.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO03016.1 - 0.0044 16.8 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EOO03016.1 - 0.019 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain CN_hydrolase PF00795.17 EOO03017.1 - 9.7e-34 116.3 0.0 1.2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3632 PF12311.3 EOO03018.1 - 1.9e-22 79.9 0.2 2.5e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Vac14_Fig4_bd PF11916.3 EOO03018.1 - 0.012 14.8 1.3 2.9 6.9 0.2 2.1 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding DAO PF01266.19 EOO03019.1 - 3.7e-51 174.1 5.0 4.2e-51 173.9 3.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO03019.1 - 5.9e-09 36.0 0.1 8.8e-07 29.0 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO03019.1 - 2.9e-07 30.3 1.2 0.0011 18.7 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EOO03019.1 - 1.8e-06 27.1 1.4 0.0032 16.4 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 EOO03019.1 - 2.4e-06 26.7 4.5 0.0065 15.3 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EOO03019.1 - 3.2e-05 23.8 0.0 3.2e-05 23.8 0.0 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EOO03019.1 - 8.6e-05 21.3 3.4 0.012 14.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.1 EOO03019.1 - 0.00011 22.4 0.0 0.00017 21.7 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EOO03019.1 - 0.00063 20.0 2.8 0.0028 18.0 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO03019.1 - 0.00067 18.2 2.9 0.0055 15.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EOO03019.1 - 0.0029 17.7 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO03019.1 - 0.005 15.9 1.4 0.015 14.4 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.14 EOO03019.1 - 0.014 14.4 0.7 0.028 13.5 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_2 PF00890.19 EOO03019.1 - 0.022 13.5 4.7 0.11 11.3 3.3 2.0 1 1 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EOO03019.1 - 0.028 14.0 0.7 0.053 13.1 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EOO03019.1 - 0.037 12.9 0.3 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EOO03019.1 - 0.038 13.0 1.1 0.83 8.6 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EOO03019.1 - 0.055 13.1 0.3 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 EOO03019.1 - 0.057 12.4 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase ApbA PF02558.11 EOO03019.1 - 0.061 12.7 4.3 0.066 12.6 0.9 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EOO03019.1 - 0.084 11.9 0.3 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 EOO03019.1 - 0.16 10.1 0.2 0.4 8.7 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) ADH_zinc_N PF00107.21 EOO03020.1 - 5e-22 77.8 0.0 9e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03020.1 - 1.4e-09 38.9 0.0 3.7e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EOO03020.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Acyl-CoA_dh_1 PF00441.19 EOO03021.1 - 1.5e-40 138.7 0.5 2.2e-40 138.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EOO03021.1 - 5e-22 77.1 0.1 1.1e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EOO03021.1 - 2.2e-19 69.0 0.4 3.9e-19 68.2 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EOO03021.1 - 1.1e-16 61.4 0.0 2.9e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EOO03021.1 - 7.3e-08 32.7 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 EOO03022.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03022.1 - 5.3e-12 46.0 0.0 6.4e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03022.1 - 4.4e-08 32.9 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO03022.1 - 0.00032 20.7 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EOO03022.1 - 0.1 11.5 0.1 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Pkinase PF00069.20 EOO03023.1 - 9.5e-47 159.3 0.0 1.2e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03023.1 - 1.7e-24 86.2 0.0 2.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO03023.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO03023.1 - 0.06 12.4 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_luciferase PF00296.15 EOO03024.1 - 6.1e-68 229.2 0.0 7.4e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.17 EOO03025.1 - 1.3e-53 182.1 0.0 7.2e-53 179.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FixQ PF05545.6 EOO03025.1 - 0.28 10.8 1.6 0.37 10.4 0.3 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Acyl-CoA_dh_N PF02771.11 EOO03026.1 - 1.5e-24 86.7 0.1 4e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EOO03026.1 - 3.1e-22 79.2 1.0 4.9e-22 78.6 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EOO03026.1 - 2.8e-18 65.1 0.0 8.1e-18 63.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EOO03026.1 - 4e-07 30.3 0.8 6.7e-07 29.6 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S8 PF00082.17 EOO03027.1 - 3.8e-46 157.5 4.4 5.3e-46 157.0 3.0 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EOO03027.1 - 0.0043 17.5 0.0 0.0077 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cerato-platanin PF07249.7 EOO03027.1 - 0.044 13.7 0.2 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 Cerato-platanin adh_short PF00106.20 EOO03028.1 - 1.8e-27 96.3 0.1 2.7e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03028.1 - 1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03028.1 - 6.3e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO03028.1 - 0.0032 17.5 0.1 0.0054 16.7 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EOO03028.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ank PF00023.25 EOO03029.1 - 7.2e-25 85.5 9.2 1.2e-09 37.4 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 EOO03029.1 - 8.9e-24 83.6 0.0 1.4e-12 47.8 0.0 4.0 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EOO03029.1 - 9.7e-22 76.9 0.2 7.1e-07 29.5 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO03029.1 - 4.9e-19 66.5 0.9 7.2e-08 31.9 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EOO03029.1 - 9.9e-15 54.2 3.4 2.3e-05 24.4 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Cys_Met_Meta_PP PF01053.15 EOO03030.1 - 3.5e-125 417.2 0.0 4e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EOO03030.1 - 2.3e-12 46.6 0.1 8.2e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EOO03030.1 - 3.9e-11 42.3 0.1 6e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EOO03030.1 - 5.8e-09 35.3 0.0 8.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EOO03030.1 - 3.4e-06 26.4 0.0 6.3e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EOO03030.1 - 0.0003 19.6 0.0 0.00048 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 EOO03030.1 - 0.0018 16.8 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Met_gamma_lyase PF06838.6 EOO03030.1 - 0.095 10.9 0.0 0.18 10.0 0.0 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase CPSase_L_D2 PF02786.12 EOO03030.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AA_permease_2 PF13520.1 EOO03031.1 - 3.1e-52 177.5 51.8 3.9e-52 177.2 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO03031.1 - 2.5e-32 111.8 46.4 2.9e-32 111.6 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 EOO03032.1 - 7.2e-05 22.9 0.2 0.034 14.2 0.0 3.4 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO03032.1 - 0.019 15.3 0.1 0.44 10.9 0.1 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EOO03032.1 - 0.037 14.1 0.2 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pyr_redox_2 PF07992.9 EOO03032.1 - 0.057 13.2 0.5 1.5 8.6 0.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EOO03032.1 - 0.15 10.9 0.4 4.3 6.1 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FlxA PF14282.1 EOO03033.1 - 0.012 15.6 0.2 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein R3H PF01424.17 EOO03033.1 - 0.03 14.0 0.4 0.1 12.2 0.0 2.1 3 0 0 3 3 3 0 R3H domain Baculo_PEP_C PF04513.7 EOO03033.1 - 0.088 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.6 EOO03033.1 - 0.09 12.0 1.0 0.15 11.2 0.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein Tweety PF04906.8 EOO03033.1 - 0.14 10.5 0.2 0.19 10.0 0.1 1.1 1 0 0 1 1 1 0 Tweety Hemagglutinin PF00509.13 EOO03033.1 - 0.18 9.9 0.2 0.24 9.4 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin ABC_tran PF00005.22 EOO03034.1 - 1.4e-11 44.8 0.0 3.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EOO03034.1 - 6.9e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EOO03034.1 - 0.00065 18.4 0.0 0.00099 17.7 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EOO03034.1 - 0.0044 16.8 0.2 0.11 12.3 0.1 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EOO03034.1 - 0.0074 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Glyco_hydro_1 PF00232.13 EOO03036.1 - 2.3e-114 382.0 0.0 2.8e-114 381.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Voltage_CLC PF00654.15 EOO03037.1 - 2.1e-93 313.1 21.6 2.1e-93 313.1 15.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 EOO03037.1 - 6.1 7.1 15.2 0.046 13.7 3.0 3.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Peptidase_M24 PF00557.19 EOO03038.1 - 2.7e-41 141.4 0.1 4e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EOO03038.1 - 1.2e-25 90.4 0.0 3.1e-21 76.2 0.0 2.7 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain WD40 PF00400.27 EOO03039.1 - 6.8e-05 22.5 0.8 0.00021 21.0 0.6 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EOO03039.1 - 0.075 12.4 0.2 1.3 8.4 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain P5CR_dimer PF14748.1 EOO03040.1 - 4.9e-33 113.3 0.6 8.1e-33 112.6 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Neurochondrin PF05536.6 EOO03041.1 - 1.2e-95 320.8 1.9 1.5e-95 320.5 1.3 1.0 1 0 0 1 1 1 1 Neurochondrin DUF3730 PF12530.3 EOO03041.1 - 0.0065 16.4 0.2 4.4 7.1 0.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3730) RIX1 PF08167.7 EOO03041.1 - 0.036 13.7 0.2 0.54 9.9 0.0 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.2 EOO03041.1 - 0.73 9.2 4.2 0.26 10.6 0.2 2.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.20 EOO03042.1 - 9.6e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FHA PF00498.21 EOO03042.1 - 1.3e-12 47.6 0.0 3.8e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 FHA domain Pkinase_Tyr PF07714.12 EOO03042.1 - 3.5e-08 32.8 0.0 5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Whi5 PF08528.6 EOO03043.1 - 8e-09 34.8 0.1 1.3e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Whi5 like CTK3 PF12243.3 EOO03044.1 - 3.1e-60 201.8 1.2 4.4e-60 201.3 0.9 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EOO03044.1 - 1.9e-20 72.6 7.2 5e-20 71.3 5.0 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 EOO03044.1 - 0.041 13.6 0.2 0.076 12.7 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial glycoprotein Fib_alpha PF08702.5 EOO03044.1 - 0.19 11.8 3.1 3 7.9 0.4 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_S10 PF00338.17 EOO03045.1 - 9.6e-23 79.8 0.0 1.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e AAA_5 PF07728.9 EOO03046.1 - 1.9e-53 179.9 1.9 3.2e-22 78.7 0.0 4.6 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 EOO03046.1 - 4.2e-14 52.8 0.2 0.0003 20.9 0.0 4.0 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO03046.1 - 2.1e-13 51.1 0.3 6.3e-05 23.7 0.0 4.1 3 1 0 3 3 3 3 AAA domain AAA_14 PF13173.1 EOO03046.1 - 2.5e-12 46.7 0.1 1.3e-05 25.1 0.0 4.5 4 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EOO03046.1 - 8.3e-12 45.3 3.3 0.0018 18.4 0.2 4.5 4 1 0 4 4 3 3 AAA domain AAA_3 PF07726.6 EOO03046.1 - 1e-11 44.5 0.1 1.1e-05 25.0 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EOO03046.1 - 1.3e-11 43.9 0.0 0.0005 19.0 0.0 3.7 4 0 0 4 4 4 2 Type II/IV secretion system protein Sigma54_activat PF00158.21 EOO03046.1 - 1.7e-11 43.8 0.1 0.0018 17.7 0.0 3.8 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_16 PF13191.1 EOO03046.1 - 1.8e-11 44.3 7.2 6.7e-07 29.4 0.4 4.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 EOO03046.1 - 4.2e-11 43.2 0.2 0.00039 20.7 0.0 3.7 3 0 0 3 3 3 3 AAA domain Sigma54_activ_2 PF14532.1 EOO03046.1 - 1e-10 41.7 0.1 8.3e-06 25.8 0.0 3.7 4 0 0 4 4 3 1 Sigma-54 interaction domain RuvB_N PF05496.7 EOO03046.1 - 5.5e-10 38.6 0.1 0.0024 16.9 0.0 4.1 4 0 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EOO03046.1 - 3e-09 36.4 0.8 0.028 14.1 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain Zeta_toxin PF06414.7 EOO03046.1 - 3.3e-08 32.8 0.9 0.062 12.3 0.0 4.7 5 0 0 5 5 5 2 Zeta toxin AAA_33 PF13671.1 EOO03046.1 - 5.1e-08 32.9 0.8 0.089 12.6 0.0 4.5 4 1 1 5 5 4 2 AAA domain UPF0079 PF02367.12 EOO03046.1 - 1.2e-07 31.3 0.1 0.0054 16.3 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EOO03046.1 - 1.3e-07 31.7 0.3 0.014 15.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase MobB PF03205.9 EOO03046.1 - 1.7e-07 31.0 0.0 0.059 13.0 0.0 3.5 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EOO03046.1 - 8.2e-07 29.4 1.8 0.00045 20.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter AAA_30 PF13604.1 EOO03046.1 - 1.9e-06 27.6 0.3 3.2 7.2 0.0 4.7 4 1 0 4 4 4 0 AAA domain Mg_chelatase PF01078.16 EOO03046.1 - 2.1e-06 27.0 0.3 7.8 5.5 0.0 5.4 5 1 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EOO03046.1 - 2.7e-06 27.4 0.2 0.38 10.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EOO03046.1 - 3e-06 26.9 0.2 0.2 11.2 0.0 3.6 3 0 0 3 3 3 2 NACHT domain AAA_29 PF13555.1 EOO03046.1 - 3.5e-06 26.4 0.0 1.3 8.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain PduV-EutP PF10662.4 EOO03046.1 - 1.3e-05 24.6 0.1 0.0048 16.3 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EOO03046.1 - 2.5e-05 24.0 0.0 0.45 10.1 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase Miro PF08477.8 EOO03046.1 - 7.7e-05 23.1 0.6 0.73 10.3 0.0 3.8 4 0 0 4 4 3 1 Miro-like protein IstB_IS21 PF01695.12 EOO03046.1 - 7.9e-05 22.1 0.0 2.2 7.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF258 PF03193.11 EOO03046.1 - 8.6e-05 21.7 0.0 0.33 10.1 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EOO03046.1 - 0.00011 21.2 0.0 0.37 9.7 0.0 3.1 3 0 0 3 3 3 2 KAP family P-loop domain ResIII PF04851.10 EOO03046.1 - 0.0002 21.2 0.0 0.62 9.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_2 PF07724.9 EOO03046.1 - 0.00029 20.8 0.0 0.33 10.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) SRP54 PF00448.17 EOO03046.1 - 0.00043 19.7 0.2 0.27 10.6 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EOO03046.1 - 0.00048 19.5 0.0 0.22 10.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 EOO03046.1 - 0.00062 18.5 0.0 0.14 10.8 0.0 3.0 3 0 0 3 3 3 1 TIP49 C-terminus AAA_24 PF13479.1 EOO03046.1 - 0.00065 19.3 0.0 4.6 6.7 0.0 3.8 5 0 0 5 5 3 0 AAA domain DEAD PF00270.24 EOO03046.1 - 0.00081 18.9 0.2 0.42 10.0 0.0 3.5 4 0 0 4 4 3 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.18 EOO03046.1 - 0.0011 18.9 0.2 13 5.7 0.0 3.8 4 0 0 4 4 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EOO03046.1 - 0.0021 17.7 2.0 3.3 7.3 0.1 3.7 4 0 0 4 4 3 0 NTPase Rad17 PF03215.10 EOO03046.1 - 0.0022 16.7 0.0 0.096 11.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EOO03046.1 - 0.0026 16.8 0.0 0.62 9.1 0.0 3.0 3 0 0 3 3 3 1 KaiC DUF815 PF05673.8 EOO03046.1 - 0.004 16.1 0.1 0.51 9.2 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EOO03046.1 - 0.0059 16.2 0.2 6.4 6.2 0.0 3.4 3 1 0 3 3 3 0 AAA domain SRPRB PF09439.5 EOO03046.1 - 0.0069 15.6 0.1 5.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 EOO03046.1 - 0.0069 15.6 0.0 0.54 9.4 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein cobW PF02492.14 EOO03046.1 - 0.011 15.2 0.6 22 4.4 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EOO03046.1 - 0.011 15.3 0.1 4.2 6.8 0.0 3.5 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EOO03046.1 - 0.017 14.0 0.0 2.8 6.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 EOO03046.1 - 0.028 13.9 2.7 1.4 8.4 0.0 3.6 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 EOO03046.1 - 0.03 13.3 0.2 0.63 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_23 PF13476.1 EOO03046.1 - 0.035 14.4 9.9 1.2 9.4 0.0 4.0 3 2 0 3 3 3 0 AAA domain CPT PF07931.7 EOO03046.1 - 0.039 13.5 1.3 6.4 6.3 0.0 4.0 4 1 1 5 5 5 0 Chloramphenicol phosphotransferase-like protein DAP3 PF10236.4 EOO03046.1 - 0.039 12.8 0.0 12 4.6 0.0 3.2 4 0 0 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.13 EOO03046.1 - 0.045 13.2 0.0 1.8 7.9 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family tRNA_lig_kinase PF08303.6 EOO03046.1 - 0.08 12.8 0.0 0.44 10.4 0.0 2.3 2 1 1 3 3 1 0 tRNA ligase kinase domain Gtr1_RagA PF04670.7 EOO03046.1 - 0.13 11.3 0.0 5.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATP-synt_ab PF00006.20 EOO03046.1 - 0.15 11.5 0.0 2.8 7.3 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 EOO03046.1 - 0.2 10.9 0.9 20 4.4 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B Thymidylate_kin PF02223.12 EOO03046.1 - 0.44 9.8 3.6 1.8 7.9 0.0 3.4 4 0 0 4 4 4 0 Thymidylate kinase Xpo1 PF08389.7 EOO03047.1 - 1.1e-37 129.1 3.8 6.9e-37 126.6 0.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EOO03047.1 - 6.2e-07 28.9 0.2 1.1 9.4 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EOO03047.1 - 0.012 16.0 1.3 49 4.5 0.0 4.6 3 1 1 4 4 4 0 HEAT-like repeat GUN4 PF05419.7 EOO03047.1 - 0.013 15.3 0.1 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 GUN4-like Cnd3 PF12719.2 EOO03047.1 - 0.037 13.0 0.1 0.16 10.9 0.0 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain FAD_binding_7 PF03441.9 EOO03048.1 - 2.5e-86 289.3 0.1 3.4e-86 288.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EOO03048.1 - 1.4e-32 112.6 0.0 3.9e-32 111.2 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase DNA_ligase_A_M PF01068.16 EOO03049.1 - 8.5e-59 198.3 1.0 1.3e-47 161.7 0.2 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EOO03049.1 - 6.3e-53 179.1 0.0 1.5e-52 177.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EOO03049.1 - 3e-28 98.0 0.0 2e-27 95.4 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EOO03049.1 - 0.052 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EOO03049.1 - 0.11 12.2 0.6 21 4.8 0.0 3.2 3 0 0 3 3 3 0 DNA ligase OB-like domain GFA PF04828.9 EOO03050.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EOO03050.1 - 0.38 10.0 3.0 0.15 11.2 0.3 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Sec15 PF04091.7 EOO03051.1 - 1.1e-116 389.5 3.1 1.1e-116 389.5 2.2 2.0 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EOO03051.1 - 0.0017 17.8 4.0 0.0052 16.2 2.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ATP13 PF12921.2 EOO03051.1 - 0.053 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase expression Peptidase_M18 PF02127.10 EOO03052.1 - 8.7e-168 558.2 0.0 4e-167 556.1 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EOO03052.1 - 4.1e-06 25.7 0.0 0.00092 18.0 0.0 2.6 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Hat1_N PF10394.4 EOO03053.1 - 1e-41 142.6 0.0 1.9e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EOO03053.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1b PF00579.20 EOO03054.1 - 7.7e-56 189.3 0.0 8.3e-34 117.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) E1_dh PF00676.15 EOO03055.1 - 5.2e-112 373.4 0.1 6.4e-112 373.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EOO03055.1 - 0.001 18.0 0.1 0.0024 16.8 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase SSrecog PF03531.9 EOO03056.1 - 2.5e-76 255.9 0.0 2.5e-76 255.9 0.0 1.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EOO03056.1 - 1.3e-23 82.7 0.0 9.4e-23 80.0 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EOO03056.1 - 0.09 11.9 0.0 0.09 11.9 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain CDC45 PF02724.9 EOO03056.1 - 4 5.3 11.1 7.3 4.4 7.7 1.5 1 0 0 1 1 1 0 CDC45-like protein RRM_2 PF04059.7 EOO03058.1 - 6.3e-35 119.0 0.2 1.5e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 EutA PF06277.6 EOO03058.1 - 0.087 11.4 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA RRM_6 PF14259.1 EOO03059.1 - 2.6e-40 136.2 0.1 2.8e-11 43.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EOO03059.1 - 2e-37 126.6 0.1 1.1e-11 44.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03059.1 - 3.1e-20 71.7 0.1 3.9e-05 23.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EOO03059.1 - 1.4e-13 50.1 5.4 1.4e-13 50.1 3.8 3.2 3 0 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 EOO03059.1 - 0.0002 21.1 0.1 0.025 14.3 0.1 2.5 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 EOO03059.1 - 0.0086 16.0 0.1 0.048 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA binding domain Spo7_2_N PF15407.1 EOO03059.1 - 0.0089 15.4 0.0 0.25 10.8 0.0 2.6 2 0 0 2 2 2 1 Sporulation protein family 7 Nup35_RRM_2 PF14605.1 EOO03059.1 - 0.053 13.2 0.0 5.8 6.7 0.0 3.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EOO03059.1 - 0.067 12.6 0.0 1.1 8.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Voltage_CLC PF00654.15 EOO03060.1 - 1.9e-51 175.1 20.5 2.4e-51 174.8 14.2 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EOO03060.1 - 8.3e-08 31.9 0.0 0.0005 19.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain LacI PF00356.16 EOO03060.1 - 0.36 10.4 1.4 0.9 9.2 1.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Fcf2 PF08698.6 EOO03062.1 - 3.6e-27 94.2 0.1 1.3e-26 92.5 0.0 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Ribos_L4_asso_C PF14374.1 EOO03062.1 - 0.028 14.3 0.4 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain TMF_DNA_bd PF12329.3 EOO03062.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding CBFD_NFYB_HMF PF00808.18 EOO03063.1 - 5.5e-20 71.1 0.4 8.1e-20 70.6 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EOO03063.1 - 3.8e-11 42.9 0.1 6.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EOO03063.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sad1_UNC PF07738.8 EOO03064.1 - 5.6e-35 120.0 0.0 9.4e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 EOO03064.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Ribosomal_L12 PF00542.14 EOO03066.1 - 1.6e-19 69.6 5.0 9e-19 67.2 2.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EOO03066.1 - 0.011 16.1 4.3 0.011 16.1 3.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dor1 PF04124.7 EOO03066.1 - 0.051 12.0 0.1 0.085 11.3 0.1 1.3 1 0 0 1 1 1 0 Dor1-like family PP2C_C PF07830.8 EOO03066.1 - 0.052 13.6 0.6 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain EIIBC-GUT_N PF03612.9 EOO03066.1 - 0.092 12.3 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Nitroreductase PF00881.19 EOO03067.1 - 0.00096 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF159 PF02586.9 EOO03068.1 - 8.7e-41 139.7 0.0 1.5e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Imm17 PF15591.1 EOO03068.1 - 0.0072 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Immunity protein 17 Cellulase PF00150.13 EOO03069.1 - 3.2e-52 177.4 0.3 3.7e-52 177.2 0.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rnf-Nqr PF02508.9 EOO03070.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Geminin PF07412.7 EOO03071.1 - 0.03 14.0 0.2 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Geminin Ank_2 PF12796.2 EOO03072.1 - 2e-121 396.6 7.3 2.1e-16 59.9 0.0 8.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EOO03072.1 - 2.2e-101 326.9 2.5 4.2e-06 26.2 0.0 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_3 PF13606.1 EOO03072.1 - 1.5e-90 287.9 0.0 5.1e-05 23.1 0.0 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.1 EOO03072.1 - 1.5e-89 292.9 15.4 1.4e-10 41.4 0.0 11.2 4 3 8 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO03072.1 - 2.3e-72 237.3 10.4 5.4e-08 32.8 0.0 12.8 2 2 12 14 14 14 14 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.12 EOO03072.1 - 2.4e-06 27.2 0.3 2.4 8.0 0.0 6.2 5 2 1 6 6 6 1 Ribosomal protein S6 DUF1874 PF08960.5 EOO03072.1 - 2e-05 24.2 7.1 7.3 6.3 0.0 8.8 6 4 5 12 12 12 1 Domain of unknown function (DUF1874) DUF362 PF04015.7 EOO03072.1 - 2.2e-05 24.0 0.0 9.8 5.5 0.0 5.8 1 1 6 7 7 7 1 Domain of unknown function (DUF362) Nse4-Nse3_bdg PF15412.1 EOO03072.1 - 5.7e-05 22.8 17.4 27 4.6 0.0 10.6 13 0 0 13 13 13 0 Binding domain of Nse4/EID3 to Nse3-MAGE AMNp_N PF10423.4 EOO03072.1 - 0.0069 15.9 0.0 45 3.5 0.0 5.2 5 2 2 7 7 7 0 Bacterial AMP nucleoside phosphorylase N-terminus Diphtheria_R PF01324.14 EOO03072.1 - 0.012 15.1 3.6 28 4.2 0.0 6.9 3 3 9 12 12 12 0 Diphtheria toxin, R domain DUF2285 PF10074.4 EOO03072.1 - 0.016 15.5 1.1 27 5.1 0.0 5.8 7 2 2 9 9 8 0 Uncharacterized conserved protein (DUF2285) SchA_CurD PF04486.7 EOO03072.1 - 0.23 11.3 4.2 70 3.3 0.0 6.4 6 5 4 10 10 10 0 SchA/CurD like domain Ank_5 PF13857.1 EOO03073.1 - 5.4e-14 51.8 0.3 2.2e-07 30.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EOO03073.1 - 5.3e-13 49.1 0.0 8.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EOO03073.1 - 1.5e-12 47.6 0.3 1.8e-06 28.2 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EOO03073.1 - 9.5e-11 40.9 0.1 8.1e-06 25.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat HTH_33 PF13592.1 EOO03073.1 - 3.2e-07 29.7 0.0 6.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Ank_3 PF13606.1 EOO03073.1 - 1.1e-05 25.2 0.0 0.00066 19.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat DDE_3 PF13358.1 EOO03073.1 - 1.1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EOO03073.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.1 EOO03073.1 - 0.034 14.1 0.1 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain HTH_29 PF13551.1 EOO03073.1 - 0.042 13.9 0.1 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DUF2457 PF10446.4 EOO03074.1 - 0.043 12.5 9.4 0.044 12.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BMF PF15185.1 EOO03074.1 - 0.052 12.8 3.3 0.066 12.5 2.3 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Daxx PF03344.10 EOO03074.1 - 0.18 10.2 9.3 0.18 10.2 6.5 1.0 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EOO03074.1 - 0.38 10.2 8.9 0.47 9.9 6.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EOO03074.1 - 0.63 9.6 7.7 0.75 9.3 5.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.8 EOO03074.1 - 0.74 8.4 10.1 0.88 8.2 7.0 1.0 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.7 EOO03074.1 - 0.75 8.9 6.0 0.82 8.8 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EOO03074.1 - 0.97 7.3 7.3 0.96 7.3 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 EOO03074.1 - 1.5 7.9 4.9 1.7 7.7 3.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 EOO03074.1 - 2 8.1 5.6 2.4 7.9 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 EOO03074.1 - 2.3 6.3 8.0 2.5 6.1 5.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein ABC_tran PF00005.22 EOO03076.1 - 2.9e-49 166.8 0.1 4.3e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EOO03076.1 - 2.5e-22 79.5 12.7 2.5e-22 79.5 8.8 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 EOO03076.1 - 1e-09 38.7 0.5 0.024 14.6 0.0 4.1 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 EOO03076.1 - 7e-09 35.2 2.1 0.19 10.9 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EOO03076.1 - 4.1e-07 30.1 0.6 0.021 14.8 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EOO03076.1 - 1.7e-06 27.4 0.5 0.017 14.6 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EOO03076.1 - 6.5e-06 25.4 0.4 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF815 PF05673.8 EOO03076.1 - 2.4e-05 23.4 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EOO03076.1 - 4.5e-05 23.3 0.2 0.1 12.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EOO03076.1 - 9.8e-05 22.5 1.2 0.54 10.3 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EOO03076.1 - 0.00015 21.2 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EOO03076.1 - 0.0003 21.2 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EOO03076.1 - 0.0003 20.6 0.1 0.037 13.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EOO03076.1 - 0.00051 19.2 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 EOO03076.1 - 0.00082 19.7 0.4 0.078 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EOO03076.1 - 0.00092 19.4 0.3 0.17 12.0 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EOO03076.1 - 0.0036 16.7 0.5 0.26 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EOO03076.1 - 0.0049 17.0 0.0 3.4 7.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase Viral_helicase1 PF01443.13 EOO03076.1 - 0.0055 16.2 0.0 4.3 6.7 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EOO03076.1 - 0.0069 15.3 1.2 0.5 9.2 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 EOO03076.1 - 0.0073 16.2 0.5 5.9 6.8 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EOO03076.1 - 0.019 14.6 0.2 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EOO03076.1 - 0.045 13.2 0.3 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EOO03076.1 - 0.054 12.3 0.1 0.41 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 EOO03076.1 - 0.059 12.4 0.1 0.92 8.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family TrwB_AAD_bind PF10412.4 EOO03076.1 - 0.12 11.0 0.1 3.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.4 EOO03076.1 - 0.12 11.8 2.2 0.3 10.5 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 EOO03076.1 - 0.17 10.4 0.2 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_33 PF13671.1 EOO03076.1 - 0.2 11.5 0.0 27 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EOO03076.1 - 0.2 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EOO03076.1 - 0.21 11.2 0.6 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad21_Rec8_N PF04825.8 EOO03077.1 - 1.4e-27 95.8 0.0 2.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EOO03077.1 - 2e-08 33.2 0.0 4.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.9 EOO03079.1 - 4.8e-90 301.6 0.1 6.3e-90 301.2 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EOO03079.1 - 7.8e-29 99.9 0.0 1.6e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.20 EOO03080.1 - 3.5e-18 66.0 2.0 2e-17 63.5 1.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03080.1 - 7e-06 25.9 0.2 3.7e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03080.1 - 7.9e-05 22.3 0.8 0.0014 18.3 0.5 2.4 1 1 0 1 1 1 1 KR domain GDI PF00996.13 EOO03081.1 - 4.4e-12 45.0 0.0 4.8e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor AA_permease_2 PF13520.1 EOO03083.1 - 7.5e-67 225.7 15.8 9.4e-67 225.3 10.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO03083.1 - 3.6e-13 48.6 13.3 3.6e-13 48.6 9.2 2.1 2 0 0 2 2 2 2 Amino acid permease Legionella_OMP PF05150.7 EOO03084.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor DUF572 PF04502.8 EOO03084.1 - 2.3 7.3 15.7 2 7.5 3.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Bac_luciferase PF00296.15 EOO03085.1 - 1.5e-37 129.4 0.0 1.7e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Enterotoxin_a PF01375.12 EOO03085.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain ADH_N PF08240.7 EOO03086.1 - 1.6e-06 27.8 0.0 4.7e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03086.1 - 2e-05 24.1 0.1 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-CCHC PF00098.18 EOO03087.1 - 0.012 15.5 1.5 0.026 14.4 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3584 PF12128.3 EOO03088.1 - 6.8e-05 20.4 60.9 6.8e-05 20.4 42.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) GAS PF13851.1 EOO03088.1 - 0.0054 15.9 5.5 0.0054 15.9 3.8 6.0 1 1 5 6 6 6 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EOO03088.1 - 0.032 12.8 90.1 0.17 10.5 16.3 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF4355 PF14265.1 EOO03090.1 - 0.0033 17.3 0.9 0.0033 17.3 0.7 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4355) tRNA-synt_1c PF00749.16 EOO03090.1 - 0.059 12.0 0.4 0.11 11.1 0.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain RTA1 PF04479.8 EOO03091.1 - 1.2e-30 106.6 2.4 1.5e-30 106.4 1.7 1.0 1 0 0 1 1 1 1 RTA1 like protein Cation_ATPase_C PF00689.16 EOO03091.1 - 0.039 13.4 0.6 0.057 12.9 0.4 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus YqjK PF13997.1 EOO03091.1 - 0.085 13.0 0.2 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 YqjK-like protein DUF2207 PF09972.4 EOO03091.1 - 0.2 10.2 4.5 0.059 11.9 1.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CTV_P6 PF06706.6 EOO03091.1 - 0.78 9.2 7.2 0.085 12.3 1.7 1.8 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein GAS PF13851.1 EOO03092.1 - 0.0014 17.8 78.9 0.022 13.9 13.4 5.7 2 2 4 6 6 6 4 Growth-arrest specific micro-tubule binding IncA PF04156.9 EOO03092.1 - 0.0065 16.0 9.5 0.0065 16.0 6.6 6.6 3 2 3 6 6 6 3 IncA protein DNAPolymera_Pol PF11590.3 EOO03092.1 - 0.011 15.4 0.3 10 5.8 0.6 3.0 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol CorA PF01544.13 EOO03092.1 - 0.018 14.0 0.3 0.018 14.0 0.2 5.2 2 1 4 6 6 6 0 CorA-like Mg2+ transporter protein BRE1 PF08647.6 EOO03092.1 - 0.045 13.7 0.7 0.045 13.7 0.5 7.4 4 2 2 6 6 6 0 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EOO03092.1 - 0.063 12.4 41.7 0.052 12.7 1.9 6.1 2 2 5 7 7 7 0 Reovirus sigma C capsid protein DUF1198 PF06711.6 EOO03092.1 - 0.56 10.0 5.7 5.8 6.7 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1198) Myosin_tail_1 PF01576.14 EOO03092.1 - 0.66 7.6 91.0 0.0037 15.0 29.0 3.0 1 1 2 3 3 3 0 Myosin tail WEMBL PF05701.6 EOO03092.1 - 1.2 7.4 76.3 0.069 11.6 18.3 4.3 1 1 1 3 3 3 0 Weak chloroplast movement under blue light ADIP PF11559.3 EOO03092.1 - 2.8 7.8 80.1 0.05 13.5 6.6 7.8 3 1 4 7 7 7 0 Afadin- and alpha -actinin-Binding ANTH PF07651.11 EOO03093.1 - 2.7e-82 275.6 0.1 1.5e-81 273.1 0.0 2.4 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EOO03093.1 - 7.8e-64 214.2 6.4 7.8e-64 214.2 4.4 5.7 5 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 EOO03093.1 - 0.001 18.9 0.0 0.0052 16.6 0.0 2.4 1 0 0 1 1 1 1 ENTH domain Med15 PF09606.5 EOO03093.1 - 0.45 8.6 30.3 0.93 7.6 21.0 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pterin_bind PF00809.17 EOO03094.1 - 5e-62 208.9 0.1 1.1e-60 204.5 0.0 2.4 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EOO03094.1 - 6.7e-33 113.1 0.0 1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.1 EOO03094.1 - 0.023 13.9 1.7 0.62 9.2 0.1 2.7 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase TRM PF02005.11 EOO03095.1 - 5.4e-107 357.9 0.0 1.9e-92 310.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EOO03095.1 - 0.00095 19.1 0.0 0.003 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EOO03095.1 - 0.0088 15.6 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EOO03095.1 - 0.022 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EOO03095.1 - 0.03 13.7 0.0 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 EOO03095.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MtrC PF04211.8 EOO03096.1 - 0.00069 18.7 0.3 0.00069 18.7 0.2 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit C Claudin_2 PF13903.1 EOO03096.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2892 PF11127.3 EOO03096.1 - 0.26 11.1 4.3 0.41 10.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) CD20 PF04103.10 EOO03096.1 - 0.29 11.0 2.2 0.47 10.3 1.6 1.4 1 1 0 1 1 1 0 CD20-like family DAGK_cat PF00781.19 EOO03097.1 - 1.9e-08 33.8 0.0 7.2e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain LTD PF00932.14 EOO03097.1 - 0.057 13.5 0.2 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Lamin Tail Domain AceK PF06315.6 EOO03097.1 - 0.16 10.1 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF87 PF01935.12 EOO03098.1 - 0.24 11.1 3.1 0.48 10.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF4061 PF13270.1 EOO03098.1 - 0.94 9.6 7.1 0.14 12.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) NYD-SP28_assoc PF14775.1 EOO03098.1 - 1 9.1 8.3 8.7 6.1 1.2 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF4613 PF15390.1 EOO03098.1 - 3.8 5.5 6.1 5.4 5.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) GRAM PF02893.15 EOO03099.1 - 4.1e-17 61.4 0.0 8e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DNA_pol_phi PF04931.8 EOO03099.1 - 1.2 6.8 5.4 1.8 6.2 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_3 PF13302.1 EOO03100.1 - 9.7e-18 64.6 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO03100.1 - 7.4e-06 25.9 0.1 1.3e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.19 EOO03101.1 - 1.6e-33 115.9 5.7 2e-33 115.6 3.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03101.1 - 3.1e-17 62.3 10.9 4.5e-17 61.8 7.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EOO03101.1 - 0.047 12.0 8.6 0.082 11.2 5.9 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein Tho2 PF11262.3 EOO03102.1 - 1.1e-82 277.4 2.2 2.1e-82 276.5 1.5 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EOO03102.1 - 1.1e-21 76.3 0.0 2.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Vps5 PF09325.5 EOO03103.1 - 1.3e-14 54.0 0.9 1.7e-14 53.6 0.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like NST1 PF13945.1 EOO03103.1 - 0.21 11.6 2.9 0.36 10.8 2.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator NB-ARC PF00931.17 EOO03104.1 - 2.5e-11 42.9 0.0 3.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EOO03104.1 - 1.5e-06 28.3 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EOO03104.1 - 0.0035 16.7 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EOO03104.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 EOO03104.1 - 0.055 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FAR1 PF03101.10 EOO03105.1 - 1.7e-06 28.4 0.0 4.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Phosphodiest PF01663.17 EOO03105.1 - 0.0021 17.4 1.1 0.0089 15.3 0.8 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4200 PF13863.1 EOO03105.1 - 0.035 14.0 10.8 0.066 13.1 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 EOO03105.1 - 0.07 12.8 4.6 0.13 12.0 3.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit MEDS PF14417.1 EOO03105.1 - 0.087 11.8 0.3 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Spc7 PF08317.6 EOO03105.1 - 0.099 11.2 3.8 0.15 10.6 2.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF262 PF03235.9 EOO03105.1 - 0.14 12.1 0.6 0.18 11.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Prefoldin PF02996.12 EOO03105.1 - 0.15 11.7 4.4 0.32 10.6 3.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit COG2 PF06148.6 EOO03105.1 - 0.3 10.9 3.2 0.64 9.8 2.2 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 EOO03105.1 - 1.2 8.8 8.7 1.4 8.6 4.8 2.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DHC_N1 PF08385.7 EOO03106.1 - 8.3e-195 648.5 4.0 8.3e-195 648.5 2.8 4.9 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EOO03106.1 - 4.5e-132 440.4 6.0 4.5e-132 440.4 4.2 5.4 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EOO03106.1 - 9.7e-104 347.8 0.0 2.2e-103 346.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EOO03106.1 - 1.3e-77 260.4 0.0 3.4e-77 259.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EOO03106.1 - 8.8e-44 149.4 0.2 1.4e-42 145.5 0.2 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EOO03106.1 - 1e-41 142.8 9.8 1e-41 142.8 6.8 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EOO03106.1 - 1.5e-41 141.7 0.5 5.7e-41 139.8 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 EOO03106.1 - 1.7e-32 112.0 0.0 2.2e-11 43.6 0.0 6.1 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EOO03106.1 - 6.8e-21 74.5 0.0 1e-19 70.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EOO03106.1 - 2.9e-15 56.5 1.0 0.01 15.9 0.0 6.6 6 1 0 6 6 5 3 AAA domain AAA PF00004.24 EOO03106.1 - 4.6e-14 52.7 0.0 0.00049 20.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO03106.1 - 6.2e-10 39.9 0.1 0.022 15.5 0.0 6.0 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 EOO03106.1 - 1.5e-09 37.8 0.1 0.34 10.7 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 EOO03106.1 - 1.9e-08 34.6 2.7 0.018 15.3 0.0 5.9 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 EOO03106.1 - 8.2e-07 28.1 0.0 0.044 12.6 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 EOO03106.1 - 1.6e-06 27.5 0.0 0.23 10.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.1 EOO03106.1 - 1.7e-06 27.9 0.0 0.23 11.3 0.0 5.1 5 0 0 5 5 3 2 AAA domain AAA_16 PF13191.1 EOO03106.1 - 4e-06 26.9 22.1 0.12 12.2 0.0 9.1 7 2 1 8 8 8 2 AAA ATPase domain AAA_19 PF13245.1 EOO03106.1 - 1.7e-05 24.4 0.1 0.89 9.3 0.0 4.8 5 0 0 5 5 5 1 Part of AAA domain ABC_tran PF00005.22 EOO03106.1 - 4.6e-05 23.7 0.1 3.1 8.1 0.0 4.9 4 0 0 4 4 3 1 ABC transporter Mg_chelatase PF01078.16 EOO03106.1 - 0.00011 21.4 0.7 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EOO03106.1 - 0.0062 15.6 5.1 0.97 8.4 0.0 4.2 4 0 0 4 4 3 2 Zeta toxin RNA_helicase PF00910.17 EOO03106.1 - 0.0092 16.1 0.1 37 4.5 0.0 4.9 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EOO03106.1 - 0.035 13.8 0.2 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EOO03106.1 - 0.038 13.3 3.6 0.4 10.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain Xpo1 PF08389.7 EOO03107.1 - 1.3e-27 96.5 5.6 2.8e-27 95.4 0.9 3.5 3 1 1 4 4 4 1 Exportin 1-like protein Adaptin_N PF01602.15 EOO03107.1 - 0.00022 19.6 0.7 0.01 14.1 0.2 2.4 2 0 0 2 2 2 2 Adaptin N terminal region IBN_N PF03810.14 EOO03107.1 - 0.00061 19.6 0.0 0.0021 17.9 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2269 PF10027.4 EOO03108.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Utp21 PF04192.7 EOO03108.1 - 0.014 14.4 3.4 0.021 13.9 2.4 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Baculo_PEP_C PF04513.7 EOO03108.1 - 0.05 13.4 0.5 0.097 12.4 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S28 PF05577.7 EOO03109.1 - 3.7e-48 164.1 0.1 5.3e-48 163.6 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EOO03109.1 - 0.00076 19.4 0.1 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 EOO03109.1 - 0.0017 17.4 0.1 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) CENP-Q PF13094.1 EOO03111.1 - 0.001 19.1 3.0 0.001 19.1 2.1 3.1 3 1 1 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit FAM92 PF06730.6 EOO03111.1 - 0.068 12.5 1.1 0.29 10.4 0.2 2.1 2 0 0 2 2 2 0 FAM92 protein Prefoldin_2 PF01920.15 EOO03111.1 - 0.14 11.8 9.9 0.095 12.4 1.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 EOO03111.1 - 0.35 11.3 4.3 1.6 9.2 0.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CASP_C PF08172.7 EOO03111.1 - 0.46 9.4 6.2 2.5 7.0 3.9 2.4 1 1 0 1 1 1 0 CASP C terminal DUF342 PF03961.8 EOO03111.1 - 1.6 7.0 7.9 0.25 9.7 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4164 PF13747.1 EOO03111.1 - 1.8 8.7 10.5 2.7 8.1 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.4 EOO03111.1 - 2 8.1 11.1 7.1 6.4 2.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain bZIP_1 PF00170.16 EOO03111.1 - 2.5 8.1 13.1 6.6 6.7 2.3 3.1 2 1 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.6 EOO03111.1 - 3.2 7.4 6.5 19 4.9 0.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EOO03111.1 - 4 7.8 6.4 17 5.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EOO03111.1 - 4.6 6.1 7.5 6.4 5.7 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 GrpE PF01025.14 EOO03111.1 - 6.4 6.2 10.8 3.5 7.1 2.8 2.4 2 0 0 2 2 2 0 GrpE TMF_DNA_bd PF12329.3 EOO03111.1 - 6.9 6.5 18.8 0.81 9.5 2.4 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ArfGap PF01412.13 EOO03112.1 - 4.2e-36 123.2 0.3 1e-35 122.0 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-H2C2_2 PF13465.1 EOO03113.1 - 1.9e-10 40.5 16.5 4e-06 26.8 2.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EOO03113.1 - 7e-08 32.3 13.6 0.0012 19.0 2.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO03113.1 - 4.2e-06 26.6 12.3 0.0062 16.7 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Dynamin_N PF00350.18 EOO03114.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.22 EOO03114.1 - 0.00089 19.5 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EOO03114.1 - 0.0022 18.7 0.1 0.0083 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EOO03114.1 - 0.0023 17.8 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EOO03114.1 - 0.0097 15.0 0.0 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin IIGP PF05049.8 EOO03114.1 - 0.0097 14.7 0.0 0.077 11.7 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EOO03114.1 - 0.011 16.2 0.0 0.037 14.5 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein DUF258 PF03193.11 EOO03114.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EOO03114.1 - 0.024 13.7 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family PRK PF00485.13 EOO03114.1 - 0.041 13.4 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EOO03114.1 - 0.064 13.4 0.1 0.33 11.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EOO03114.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EOO03114.1 - 0.069 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_1 PF00561.15 EOO03115.1 - 1.5e-41 142.4 0.0 1.1e-40 139.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO03115.1 - 2.2e-13 50.6 0.3 4.6e-12 46.3 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO03115.1 - 0.0027 17.4 0.1 0.068 12.9 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EOO03115.1 - 0.0078 14.8 0.0 0.028 13.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_4 PF08386.5 EOO03115.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein GSK-3_bind PF05350.7 EOO03116.1 - 0.11 11.9 0.8 0.21 10.9 0.6 1.6 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Solute_trans_a PF03619.11 EOO03117.1 - 6.2e-66 222.5 10.7 7.3e-66 222.2 7.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Senescence PF06911.7 EOO03119.1 - 1.5e-51 174.5 3.8 2.4e-51 173.9 2.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein OPT PF03169.10 EOO03120.1 - 6.7e-160 533.5 35.1 7.7e-160 533.3 24.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AA_permease PF00324.16 EOO03121.1 - 3.1e-83 279.7 34.7 3.4e-57 193.8 10.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EOO03121.1 - 6.2e-12 44.7 35.5 1.2e-10 40.5 9.9 2.1 1 1 1 2 2 2 2 Amino acid permease PgaD PF13994.1 EOO03121.1 - 0.41 10.1 0.0 0.41 10.1 0.0 2.8 3 0 0 3 3 3 0 PgaD-like protein Orthoreo_P10 PF07204.6 EOO03121.1 - 3.1 7.5 9.6 0.13 12.0 1.7 2.3 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 ADH_N PF08240.7 EOO03122.1 - 4.5e-26 90.7 0.6 9.9e-26 89.6 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03122.1 - 1.4e-15 57.0 0.0 4e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EOO03122.1 - 0.0096 15.3 0.2 0.02 14.2 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EOO03122.1 - 0.018 13.9 0.2 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO03122.1 - 0.018 15.0 0.1 0.054 13.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EOO03122.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EOO03122.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EOO03122.1 - 0.032 14.0 0.7 0.059 13.1 0.5 1.3 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EOO03122.1 - 0.036 13.7 0.1 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EOO03122.1 - 0.049 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EOO03122.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EOO03122.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_N PF00732.14 EOO03123.1 - 9e-61 205.6 0.0 3.5e-59 200.3 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO03123.1 - 3.6e-31 108.3 0.0 9.9e-31 106.9 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EOO03123.1 - 3.7e-05 23.6 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EOO03123.1 - 0.00032 19.7 0.1 0.00051 19.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EOO03123.1 - 0.00087 18.2 0.1 0.0032 16.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO03123.1 - 0.0017 18.4 0.0 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO03123.1 - 0.002 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EOO03123.1 - 0.0027 16.6 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EOO03123.1 - 0.0037 15.7 0.0 0.0083 14.6 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EOO03123.1 - 0.02 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO03123.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EOO03123.1 - 0.12 11.3 0.1 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 EOO03123.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PI-PLC-X PF00388.14 EOO03124.1 - 3.9e-08 32.8 0.0 4.6e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF221 PF02714.10 EOO03125.1 - 1.3e-103 346.2 24.5 3.3e-103 344.9 16.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EOO03125.1 - 5.1e-46 156.1 0.9 5.1e-46 156.1 0.6 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EOO03125.1 - 3.5e-29 100.5 0.5 8.5e-29 99.3 0.1 1.8 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EOO03125.1 - 1.8e-21 76.4 1.2 3.2e-21 75.6 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2456 PF10445.4 EOO03125.1 - 1.4 8.9 11.8 1.1 9.1 3.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) Spc97_Spc98 PF04130.8 EOO03126.1 - 1.1e-69 235.2 0.0 3.2e-69 233.7 0.0 1.7 1 1 0 1 1 1 1 Spc97 / Spc98 family TIM21 PF08294.6 EOO03127.1 - 1.1e-40 138.6 0.0 1.2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EOO03127.1 - 1.6e-06 27.5 0.0 3.7e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 NMO PF03060.10 EOO03128.1 - 1e-72 245.0 1.2 1.3e-72 244.7 0.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EOO03128.1 - 3.9e-10 39.1 1.4 6.7e-10 38.3 1.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EOO03128.1 - 7.3e-07 28.3 2.1 1.4e-06 27.4 1.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EOO03128.1 - 0.0022 17.0 0.2 0.0041 16.1 0.2 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EOO03128.1 - 0.014 14.3 1.1 0.031 13.1 0.8 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.9 EOO03128.1 - 0.036 13.0 1.6 0.04 12.8 0.1 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase End3 PF12761.2 EOO03129.1 - 0.054 13.1 0.1 5.5 6.5 0.0 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 POX PF07526.6 EOO03130.1 - 0.0032 17.6 1.2 0.0032 17.6 0.8 2.1 3 0 0 3 3 3 1 Associated with HOX DUF1251 PF06856.6 EOO03130.1 - 0.084 12.3 0.3 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1251) ABC_tran PF00005.22 EOO03131.1 - 1.2e-46 158.3 0.2 5.7e-22 78.4 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EOO03131.1 - 1.9e-14 54.3 5.0 2.5e-08 34.2 0.7 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EOO03131.1 - 4.3e-09 35.9 1.2 0.018 14.2 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EOO03131.1 - 3.5e-08 32.8 0.3 0.00029 20.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EOO03131.1 - 9e-08 32.0 0.1 0.005 16.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EOO03131.1 - 4e-07 30.8 1.6 0.015 16.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain ABC_tran_2 PF12848.2 EOO03131.1 - 4.1e-06 26.5 1.4 1.4e-05 24.8 1.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EOO03131.1 - 5.6e-06 26.4 7.1 0.038 13.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EOO03131.1 - 7.9e-06 26.3 0.0 0.04 14.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EOO03131.1 - 9.3e-06 24.9 0.4 0.067 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EOO03131.1 - 1.2e-05 25.3 0.5 0.0071 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EOO03131.1 - 0.0001 21.9 0.3 0.079 12.6 0.0 2.9 2 1 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 EOO03131.1 - 0.00014 21.7 0.9 0.64 9.8 0.0 3.0 3 0 0 3 3 2 2 Dynamin family MobB PF03205.9 EOO03131.1 - 0.00017 21.3 0.3 0.21 11.2 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EOO03131.1 - 0.00018 21.8 13.4 0.045 14.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.12 EOO03131.1 - 0.00021 21.2 11.2 0.023 14.5 0.3 3.7 4 0 0 4 4 4 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EOO03131.1 - 0.0003 20.9 7.9 0.42 10.7 0.1 4.3 4 2 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EOO03131.1 - 0.00059 19.4 0.1 0.24 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EOO03131.1 - 0.0007 19.8 4.5 0.12 12.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EOO03131.1 - 0.00075 18.3 3.1 0.13 10.9 0.2 2.4 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EOO03131.1 - 0.00075 19.3 1.1 1 9.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA PF00004.24 EOO03131.1 - 0.0015 18.7 0.4 0.42 10.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EOO03131.1 - 0.0015 18.4 0.3 2.5 7.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EOO03131.1 - 0.0027 17.1 0.1 0.56 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EOO03131.1 - 0.0037 16.7 1.1 0.8 9.0 0.1 2.9 3 0 0 3 3 2 1 AAA-like domain DUF815 PF05673.8 EOO03131.1 - 0.0048 15.8 1.5 0.91 8.3 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EOO03131.1 - 0.005 16.5 0.3 4 7.1 0.0 3.1 3 0 0 3 3 3 0 NTPase Arf PF00025.16 EOO03131.1 - 0.0065 15.7 0.7 0.099 11.8 0.2 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EOO03131.1 - 0.0066 16.6 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EOO03131.1 - 0.0075 15.7 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EOO03131.1 - 0.01 15.6 1.5 0.41 10.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EOO03131.1 - 0.021 14.4 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EOO03131.1 - 0.035 13.1 0.2 7.4 5.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.12 EOO03131.1 - 0.047 13.0 3.1 0.49 9.7 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase FtsK_SpoIIIE PF01580.13 EOO03131.1 - 0.047 13.1 0.2 1 8.7 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EOO03131.1 - 0.059 12.8 0.9 11 5.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EOO03131.1 - 0.071 12.8 1.5 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain NB-ARC PF00931.17 EOO03131.1 - 0.072 11.9 1.4 3.4 6.4 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.4 EOO03131.1 - 0.074 12.5 0.3 3.7 7.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EOO03131.1 - 0.13 10.6 11.9 0.045 12.2 0.2 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EOO03131.1 - 0.64 9.0 6.5 0.58 9.1 0.0 3.1 4 0 0 4 4 3 0 AAA ATPase domain GTP_EFTU PF00009.22 EOO03132.1 - 1.8e-39 135.1 0.0 3.1e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EOO03132.1 - 3.5e-22 78.0 0.0 8.9e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EOO03132.1 - 3.3e-15 55.7 0.0 9.4e-14 51.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EOO03132.1 - 4.4e-05 23.5 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EOO03132.1 - 0.073 12.6 0.0 1.7 8.2 0.0 2.6 1 1 0 1 1 1 0 Elongation factor G, domain IV Myb_Cef PF11831.3 EOO03133.1 - 1.7e-58 197.5 5.4 1.7e-58 197.5 3.8 3.4 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EOO03133.1 - 1.7e-21 75.9 4.6 1.8e-10 40.6 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EOO03133.1 - 8.6e-21 73.8 8.8 5.3e-15 55.2 2.2 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EOO03133.1 - 0.028 14.3 1.7 0.7 9.8 0.0 3.7 2 2 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribosomal_S8e PF01201.17 EOO03133.1 - 3.3 7.8 9.7 0.14 12.3 0.7 2.5 2 0 0 2 2 2 0 Ribosomal protein S8e JAB PF01398.16 EOO03134.1 - 3.6e-10 39.5 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EOO03134.1 - 0.0018 18.3 0.0 0.0067 16.5 0.0 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2005 PF09407.5 EOO03134.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) SMC_Nse1 PF07574.8 EOO03135.1 - 4.4e-40 137.4 0.0 5.8e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EOO03135.1 - 1.5e-13 50.4 11.2 2.3e-13 49.9 7.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EOO03135.1 - 3.7 7.4 6.9 6 6.7 4.8 1.3 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.2 EOO03135.1 - 8.5 6.2 8.7 45 3.9 6.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon 5-FTHF_cyc-lig PF01812.15 EOO03136.1 - 4.8e-29 101.4 0.0 5.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Dynamin_N PF00350.18 EOO03137.1 - 1.3e-25 90.1 2.9 5.1e-25 88.2 2.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EOO03137.1 - 1.5e-18 66.6 0.1 1.1e-17 63.8 0.1 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EOO03137.1 - 1.6e-06 28.0 0.0 1.3e-05 25.1 0.0 2.5 2 2 1 3 3 3 1 50S ribosome-binding GTPase GED PF02212.13 EOO03137.1 - 0.0001 22.1 0.6 0.0014 18.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EOO03137.1 - 0.00088 19.7 0.0 0.0031 17.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 EOO03137.1 - 0.012 15.6 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EOO03137.1 - 0.053 12.6 0.0 2 7.5 0.1 2.5 2 0 0 2 2 2 0 AIG1 family DUF1774 PF08611.5 EOO03138.1 - 8.9e-34 115.5 4.3 8.9e-34 115.5 3.0 2.2 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Adeno_E3 PF06040.6 EOO03138.1 - 0.023 14.6 0.1 0.07 13.0 0.0 1.7 1 1 0 1 1 1 0 Adenovirus E3 protein SPRY PF00622.23 EOO03139.1 - 1.9e-09 37.6 0.0 2e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 SPRY domain Acetyltransf_1 PF00583.19 EOO03140.1 - 2.2e-06 27.6 0.1 9.7e-06 25.5 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EOO03140.1 - 0.0011 19.0 0.1 0.0028 17.7 0.0 1.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Nop53 PF07767.6 EOO03142.1 - 0.032 13.2 0.7 0.043 12.8 0.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SUR7 PF06687.7 EOO03143.1 - 1.7e-11 44.0 12.5 1.7e-11 44.0 8.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.9 EOO03143.1 - 0.013 15.3 5.0 0.02 14.7 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Claudin_2 PF13903.1 EOO03143.1 - 0.015 15.0 10.9 0.02 14.5 7.6 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3169 PF11368.3 EOO03143.1 - 0.14 11.3 6.5 0.44 9.7 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) PLAC8 PF04749.12 EOO03143.1 - 0.14 12.7 0.9 0.26 11.8 0.1 1.7 1 1 1 2 2 2 0 PLAC8 family zf-DHHC PF01529.15 EOO03143.1 - 0.23 10.8 5.7 0.11 11.8 1.6 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase RseC_MucC PF04246.7 EOO03143.1 - 1 8.9 8.9 1.2 8.6 3.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Xan_ur_permease PF00860.15 EOO03144.1 - 7.8e-06 24.6 30.7 0.0063 15.0 19.2 2.2 1 1 1 2 2 2 2 Permease family Sulfate_transp PF00916.15 EOO03144.1 - 0.0025 16.8 10.2 0.0025 16.8 7.1 2.9 1 1 1 2 2 2 1 Sulfate transporter family DUF3328 PF11807.3 EOO03145.1 - 5.8e-45 153.6 1.3 6.7e-45 153.4 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NIF PF03031.13 EOO03147.1 - 2.3e-28 98.8 0.0 5.2e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EOO03147.1 - 2.9e-09 36.6 0.0 5.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EOO03147.1 - 9.4e-08 32.1 0.1 8.3e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 EOO03147.1 - 0.0038 16.8 0.1 3.2 7.4 0.0 2.9 2 1 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EOO03147.1 - 0.011 15.3 0.0 0.64 9.7 0.1 3.1 2 0 0 2 2 2 0 Biotin-lipoyl like NmrA PF05368.8 EOO03148.1 - 1.9e-20 73.1 0.1 2.3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO03148.1 - 2.4e-12 47.2 0.2 3.5e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EOO03148.1 - 0.0051 17.1 0.3 0.014 15.6 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EOO03148.1 - 0.013 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 KR domain RNase_H_2 PF13482.1 EOO03148.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 RNase_H superfamily DapB_N PF01113.15 EOO03148.1 - 0.024 14.5 0.4 0.16 11.8 0.2 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EOO03148.1 - 0.027 14.4 0.5 0.062 13.2 0.3 1.6 1 1 0 1 1 1 0 short chain dehydrogenase WHIM3 PF15614.1 EOO03148.1 - 0.086 12.6 0.1 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 F420_oxidored PF03807.12 EOO03148.1 - 0.12 12.8 0.5 0.36 11.2 0.1 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UPF0489 PF12640.2 EOO03148.1 - 0.12 12.5 0.1 0.38 10.9 0.1 1.9 1 1 0 1 1 1 0 UPF0489 domain DIOX_N PF14226.1 EOO03149.1 - 1.3e-22 80.5 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO03149.1 - 1.1e-20 73.7 0.0 2.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 EOO03150.1 - 2.1e-55 188.2 0.0 3.9e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO03150.1 - 9.5e-07 28.0 1.8 3.6e-05 22.8 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EOO03150.1 - 1.2e-05 24.0 0.0 0.00013 20.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EOO03150.1 - 4.5e-05 23.3 0.2 0.00026 20.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EOO03150.1 - 9.4e-05 22.7 0.0 0.0035 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO03150.1 - 0.0017 17.3 0.2 0.0086 14.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EOO03150.1 - 0.0026 17.8 0.0 0.0074 16.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EOO03150.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EOO03150.1 - 0.004 16.1 0.1 0.0073 15.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EOO03150.1 - 0.0041 17.0 0.1 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO03150.1 - 0.0049 15.9 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EOO03150.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_C69 PF03577.10 EOO03150.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 Asp PF00026.18 EOO03151.1 - 6.9e-54 183.2 5.7 9e-54 182.8 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO03151.1 - 1.2e-06 28.5 0.2 1.2e-06 28.5 0.1 2.0 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO03151.1 - 6.2e-05 23.4 3.1 1.9 9.0 0.0 4.3 2 2 1 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EOO03151.1 - 0.026 14.0 0.0 0.07 12.6 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EOO03151.1 - 0.032 14.0 1.3 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.19 EOO03152.1 - 7e-65 219.3 29.9 1.1e-42 146.1 2.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO03152.1 - 2.3e-09 36.4 20.2 2.3e-09 36.4 14.0 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Pectate_lyase PF03211.8 EOO03153.1 - 9.2e-45 152.6 3.7 1.2e-44 152.3 2.6 1.0 1 0 0 1 1 1 1 Pectate lyase Cnd1_N PF12922.2 EOO03155.1 - 3.3e-59 199.3 3.8 3.6e-58 195.9 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EOO03155.1 - 1.2e-57 194.5 1.5 8e-53 178.9 0.3 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EOO03155.1 - 5.9e-11 42.5 2.8 8.3e-05 22.8 0.1 5.3 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EOO03155.1 - 7.5e-08 31.8 11.3 0.033 14.2 0.0 6.6 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EOO03155.1 - 8.3e-06 26.1 4.9 0.017 15.5 0.1 5.1 4 0 0 4 4 4 1 HEAT-like repeat DUF2435 PF10363.4 EOO03155.1 - 0.0016 18.3 0.0 2.3 8.1 0.0 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EOO03155.1 - 0.0019 18.0 0.1 4.2 7.4 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EOO03155.1 - 0.057 12.3 7.6 0.012 14.6 0.8 3.3 3 2 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain UCR_14kD PF02271.11 EOO03156.1 - 0.023 14.4 2.5 3.8 7.3 0.2 2.8 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit CWC25 PF12542.3 EOO03156.1 - 0.073 13.5 1.9 6.9 7.1 1.3 2.8 1 1 0 1 1 1 0 Pre-mRNA splicing factor dCMP_cyt_deam_2 PF08211.6 EOO03156.1 - 0.29 11.1 6.1 16 5.4 3.3 3.0 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region UCH PF00443.24 EOO03157.1 - 6.5e-44 150.0 0.0 1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EOO03157.1 - 1.4e-24 85.9 11.4 8.4e-21 73.8 1.1 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EOO03157.1 - 1.3e-21 77.3 0.0 1.2e-09 38.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EOO03157.1 - 2.1e-21 75.1 0.1 1.9e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain K-box PF01486.12 EOO03157.1 - 0.097 12.4 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 K-box region Eapp_C PF10238.4 EOO03157.1 - 0.55 10.1 4.3 1.1 9.2 0.4 2.9 2 1 0 2 2 2 0 E2F-associated phosphoprotein TauD PF02668.11 EOO03158.1 - 2.2e-41 142.2 0.1 3e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HORMA PF02301.13 EOO03160.1 - 1.7e-39 135.4 0.0 1.9e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Fer4 PF00037.22 EOO03161.1 - 1.3e-13 49.8 16.5 5.1e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EOO03161.1 - 6.7e-12 45.6 10.6 1.1e-11 44.9 7.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EOO03161.1 - 5.8e-10 39.2 8.3 1.1e-09 38.4 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EOO03161.1 - 7.5e-10 39.4 7.0 0.0002 22.0 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EOO03161.1 - 1.8e-09 37.2 21.9 6.7e-08 32.2 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EOO03161.1 - 6.5e-09 35.5 32.1 1e-05 25.2 8.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 EOO03161.1 - 9.6e-08 31.9 20.3 2e-05 24.5 8.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EOO03161.1 - 1.1e-07 31.3 14.7 0.00042 20.0 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EOO03161.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EOO03161.1 - 4.9e-06 26.4 12.7 0.00056 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EOO03161.1 - 8.4e-06 26.0 10.1 0.00096 19.4 7.9 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EOO03161.1 - 2.8e-05 24.4 9.1 0.012 15.9 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EOO03161.1 - 0.0062 16.8 14.9 0.29 11.5 3.2 2.8 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EOO03161.1 - 0.011 16.2 13.0 0.21 12.1 1.1 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EOO03161.1 - 0.067 13.7 16.9 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EOO03161.1 - 0.1 12.7 4.8 0.25 11.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain zf-CCCH PF00642.19 EOO03162.1 - 2.7e-10 39.6 8.4 3.1e-05 23.5 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EOO03162.1 - 0.092 12.7 17.5 0.2 11.6 3.4 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type NifU_N PF01592.11 EOO03163.1 - 8.4e-52 174.4 0.0 1.1e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Phage_DsbA PF11126.3 EOO03164.1 - 0.14 12.2 0.6 0.21 11.6 0.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator DsbA Aminotran_1_2 PF00155.16 EOO03165.1 - 7.9e-42 143.5 0.0 1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EOO03165.1 - 5e-09 34.9 0.0 7.3e-09 34.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EOO03165.1 - 2e-08 33.7 0.0 3.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EOO03165.1 - 3.8e-07 29.1 0.0 5.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.2 EOO03165.1 - 7.8e-05 21.3 0.0 0.00094 17.8 0.0 2.0 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EOO03165.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EOO03165.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Allinase KIP1 PF07765.7 EOO03166.1 - 2.4e-05 24.0 5.3 2.7 7.8 0.0 4.0 1 1 3 4 4 4 3 KIP1-like protein Orthopox_B11R PF07033.6 EOO03166.1 - 0.00027 20.3 2.1 0.41 10.1 0.2 2.7 1 1 2 3 3 3 3 Orthopoxvirus B11R protein Renin_r PF07850.9 EOO03166.1 - 0.0028 17.9 1.9 12 6.2 0.0 3.3 1 1 2 3 3 3 2 Renin receptor-like protein UPF0183 PF03676.9 EOO03166.1 - 0.013 14.0 0.2 2.5 6.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0183) MSA-2c PF12238.3 EOO03166.1 - 0.016 14.9 9.0 0.49 10.0 1.0 2.5 1 1 1 2 2 2 0 Merozoite surface antigen 2c Put_DNA-bind_N PF06971.8 EOO03166.1 - 0.017 14.8 0.8 46 3.8 0.0 3.9 4 0 0 4 4 4 0 Putative DNA-binding protein N-terminus DUF4227 PF14004.1 EOO03166.1 - 0.039 13.8 0.5 38 4.2 0.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4227) Sialidase PF02973.11 EOO03166.1 - 0.064 12.2 0.2 3.2 6.6 0.0 2.0 1 1 1 2 2 2 0 Sialidase, N-terminal domain SBP_bac_8 PF13416.1 EOO03166.1 - 0.49 10.0 7.8 47 3.5 0.1 3.8 1 1 3 4 4 4 0 Bacterial extracellular solute-binding protein DEAD_2 PF06733.10 EOO03167.1 - 4.4e-25 88.0 0.0 6.6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EOO03167.1 - 0.00021 20.8 0.0 0.024 14.1 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EOO03167.1 - 0.00074 19.4 1.2 0.061 13.1 0.9 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EOO03167.1 - 0.0061 15.4 0.1 0.37 9.5 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EOO03167.1 - 0.023 13.9 0.2 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EOO03167.1 - 0.049 13.7 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Amidase PF01425.16 EOO03169.1 - 7.3e-06 25.0 0.0 0.029 13.2 0.0 2.1 2 0 0 2 2 2 2 Amidase Peptidase_S8 PF00082.17 EOO03170.1 - 1.9e-24 86.2 0.0 3.3e-20 72.3 0.0 2.3 1 1 1 2 2 2 2 Subtilase family DUF1034 PF06280.7 EOO03170.1 - 3.8e-06 27.2 0.0 4.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EOO03170.1 - 0.034 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Acetyltransf_1 PF00583.19 EOO03171.1 - 4.8e-15 55.3 0.0 7.6e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EOO03171.1 - 1.5e-08 34.6 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EOO03171.1 - 1.9e-07 31.2 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EOO03171.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EOO03171.1 - 0.00011 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EOO03171.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EOO03171.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EOO03171.1 - 0.091 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EOO03172.1 - 5.4e-121 404.3 22.9 6.2e-121 404.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03172.1 - 2.6e-22 79.0 49.4 1.3e-20 73.4 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_16 PF13432.1 EOO03172.1 - 0.0071 16.9 0.4 0.015 15.9 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EOO03172.1 - 0.033 13.8 0.1 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 TPR repeat DUF3154 PF11351.3 EOO03172.1 - 0.08 12.6 1.2 0.94 9.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) DUF261 PF03196.8 EOO03172.1 - 1.5 8.7 4.6 1.1 9.2 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF261 DUF2370 PF10176.4 EOO03173.1 - 4.6e-85 284.6 0.0 7.2e-85 284.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EOO03173.1 - 0.1 12.8 0.4 0.59 10.3 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Fungal_trans PF04082.13 EOO03174.1 - 3e-05 23.0 0.0 4.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EOO03175.1 - 3e-48 164.0 0.2 3.6e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HeH PF12949.2 EOO03175.1 - 0.049 13.1 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 HeH/LEM domain tRNA-synt_1d PF00750.14 EOO03176.1 - 1e-52 179.1 0.4 2.7e-52 177.7 0.3 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EOO03176.1 - 7.1e-13 48.5 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Lipocalin PF00061.18 EOO03176.1 - 0.069 13.1 1.0 0.43 10.5 0.7 2.1 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Transpeptidase PF00905.17 EOO03176.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Transp_cyt_pur PF02133.10 EOO03177.1 - 5.2e-57 193.3 22.6 6.6e-52 176.5 9.7 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PCMT PF01135.14 EOO03178.1 - 1.2e-53 181.7 0.0 3.9e-38 131.1 0.0 2.0 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EOO03178.1 - 1.3e-06 28.9 0.0 2.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03178.1 - 1.5e-06 27.8 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EOO03178.1 - 5.8e-05 22.8 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO03178.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO03178.1 - 0.0018 18.0 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO03178.1 - 0.0049 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EOO03178.1 - 0.026 14.9 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03178.1 - 0.027 14.8 0.0 0.069 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EOO03178.1 - 0.039 12.9 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 EOO03178.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 EOO03178.1 - 0.066 12.2 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase FPN1 PF06963.7 EOO03179.1 - 9.2e-63 212.1 0.2 1.1e-62 211.8 0.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DEAD PF00270.24 EOO03180.1 - 2.8e-47 160.3 0.0 2.7e-45 153.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO03180.1 - 1.3e-28 98.6 0.0 9.3e-28 95.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO03180.1 - 4e-05 23.5 7.5 5.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EOO03180.1 - 8.8e-05 21.0 0.0 8.8e-05 21.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EOO03180.1 - 0.06 12.4 0.0 0.06 12.4 0.0 3.2 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit MIP-T3 PF10243.4 EOO03180.1 - 0.44 8.9 37.2 0.64 8.4 25.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 EOO03180.1 - 2.9 8.2 11.5 4.5 7.5 8.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein FAM60A PF15396.1 EOO03180.1 - 9.8 5.8 15.5 19 4.9 10.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Transp_cyt_pur PF02133.10 EOO03181.1 - 1.5e-99 333.5 38.9 1.8e-99 333.3 27.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mito_carr PF00153.22 EOO03182.1 - 5.1e-49 163.9 4.3 1.9e-22 78.7 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.20 EOO03183.1 - 1.1e-42 146.0 0.0 7.6e-39 133.4 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03183.1 - 1.8e-14 53.4 0.0 2.7e-08 33.2 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EOO03183.1 - 6.5e-05 22.7 0.1 0.013 15.2 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EOO03183.1 - 0.00075 18.5 0.0 0.21 10.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like YL1 PF05764.8 EOO03183.1 - 0.025 14.1 10.5 0.057 13.0 7.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 EOO03183.1 - 0.091 11.2 10.8 0.13 10.6 7.5 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 EOO03183.1 - 0.25 10.9 7.6 0.46 10.0 5.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Transp_cyt_pur PF02133.10 EOO03184.1 - 3.3e-15 55.5 30.2 3.2e-13 49.0 20.9 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltransf_31 PF13847.1 EOO03185.1 - 6.1e-16 58.3 0.0 7.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO03185.1 - 6.9e-15 55.1 0.0 9.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03185.1 - 1.9e-14 54.1 0.0 9.6e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03185.1 - 1.8e-11 44.2 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03185.1 - 4.8e-11 43.0 0.0 7.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO03185.1 - 9e-11 41.8 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03185.1 - 1.7e-10 41.2 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO03185.1 - 2.1e-07 30.2 0.0 2.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EOO03185.1 - 0.00041 19.1 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.11 EOO03185.1 - 0.00041 19.3 0.0 0.23 10.3 0.0 2.1 2 0 0 2 2 2 2 mRNA capping enzyme PCMT PF01135.14 EOO03185.1 - 0.00087 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EOO03185.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EOO03185.1 - 0.0079 16.1 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EOO03185.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EOO03185.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EOO03185.1 - 0.052 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NodS PF05401.6 EOO03185.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) N2227 PF07942.7 EOO03185.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Methyltransf_20 PF12147.3 EOO03185.1 - 0.13 11.1 0.0 0.81 8.4 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase GRIM-19 PF06212.7 EOO03186.1 - 2.3e-23 82.3 0.1 3.5e-23 81.7 0.0 1.2 1 1 0 1 1 1 1 GRIM-19 protein DUF1479 PF07350.7 EOO03187.1 - 2.2e-126 421.7 0.0 2.7e-126 421.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PP-binding PF00550.20 EOO03188.1 - 8.9e-11 41.9 0.2 1.2e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EOO03188.1 - 8.3e-05 22.5 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier p450 PF00067.17 EOO03189.1 - 9.4e-74 248.5 0.0 1.2e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L18e PF00828.14 EOO03190.1 - 4.5e-33 114.3 0.0 5.3e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Man-6-P_recep PF02157.10 EOO03192.1 - 1.2e-11 44.1 0.0 2.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EOO03192.1 - 2.3e-09 36.8 5.5 6e-09 35.5 2.6 2.2 2 1 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.13 EOO03192.1 - 1.8e-07 31.0 0.2 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PBP1_TM PF14812.1 EOO03192.1 - 4.8 7.5 6.8 0.79 10.0 0.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_3 PF07859.8 EOO03193.1 - 9.1e-07 28.6 0.0 4.7e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EOO03193.1 - 0.027 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_5 PF00266.14 EOO03194.1 - 1.5e-21 76.5 0.0 2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EOO03194.1 - 8.9e-06 24.8 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EOO03194.1 - 0.00038 19.0 0.0 0.00067 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ERG4_ERG24 PF01222.12 EOO03195.1 - 2.4e-172 573.3 0.2 2.8e-172 573.1 0.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EOO03195.1 - 6.7e-06 25.5 0.1 2.1e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_S8 PF00082.17 EOO03196.1 - 1.6e-43 148.8 1.5 2.6e-43 148.1 1.0 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EOO03196.1 - 4e-07 29.6 0.0 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EOO03196.1 - 8.6e-07 29.3 0.0 3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EOO03196.1 - 0.099 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Zn_clus PF00172.13 EOO03197.1 - 3.1e-08 33.3 13.8 6.1e-08 32.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EOO03197.1 - 0.062 12.1 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain PTR2 PF00854.16 EOO03198.1 - 4.3e-44 150.8 13.3 2.9e-43 148.0 9.2 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EOO03198.1 - 8.4e-08 31.2 23.9 3.1e-07 29.4 14.6 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily YqzM PF14141.1 EOO03198.1 - 0.076 12.8 0.5 0.34 10.7 0.3 2.1 1 0 0 1 1 1 0 YqzM-like protein Asp PF00026.18 EOO03199.1 - 1.9e-58 198.2 9.7 2.3e-58 197.9 6.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO03199.1 - 9.3e-08 32.1 0.4 1.3e-05 25.2 0.1 3.5 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EOO03199.1 - 0.012 15.1 0.5 0.05 13.1 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Glyco_hydro_3 PF00933.16 EOO03200.1 - 3.2e-92 308.7 0.0 5e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO03200.1 - 9.5e-57 192.1 2.4 6.8e-56 189.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO03200.1 - 2.6e-15 56.1 0.0 5.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4064 PF13273.1 EOO03201.1 - 3.6 7.7 7.0 3.4 7.8 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ABC_tran PF00005.22 EOO03202.1 - 2.3e-47 160.7 0.0 7.6e-25 87.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EOO03202.1 - 1.4e-28 100.1 29.9 2e-20 73.3 10.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EOO03202.1 - 1.4e-10 40.8 5.7 0.0014 17.9 0.0 5.5 5 1 1 6 6 6 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EOO03202.1 - 7e-09 34.9 0.0 0.0011 17.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EOO03202.1 - 9.7e-09 34.9 0.6 0.0046 16.4 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EOO03202.1 - 2.4e-08 33.4 0.6 0.0026 17.2 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EOO03202.1 - 5.3e-08 33.0 0.0 0.0046 16.9 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.1 EOO03202.1 - 9e-08 32.4 0.1 0.12 12.2 0.1 3.4 2 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 EOO03202.1 - 9.9e-08 32.0 0.3 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EOO03202.1 - 3.4e-06 27.2 0.0 0.069 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EOO03202.1 - 5.5e-06 26.8 0.1 0.053 13.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EOO03202.1 - 8.2e-06 25.4 0.2 0.062 12.7 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EOO03202.1 - 8.9e-06 25.2 0.1 0.059 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EOO03202.1 - 9.2e-06 26.1 0.0 0.14 12.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EOO03202.1 - 1e-05 26.3 0.1 0.18 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EOO03202.1 - 3.9e-05 23.5 0.1 0.21 11.5 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EOO03202.1 - 5.1e-05 23.5 0.1 0.26 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EOO03202.1 - 7.5e-05 21.9 0.2 0.09 11.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 EOO03202.1 - 0.00012 20.8 0.2 0.22 10.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EOO03202.1 - 0.00014 21.5 0.2 0.55 9.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EOO03202.1 - 0.00054 19.5 0.9 0.18 11.3 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EOO03202.1 - 0.001 18.1 0.1 0.77 8.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EOO03202.1 - 0.0012 18.7 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_33 PF13671.1 EOO03202.1 - 0.0015 18.3 0.1 1.9 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EOO03202.1 - 0.0023 17.5 0.1 0.13 11.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EOO03202.1 - 0.0036 16.9 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EOO03202.1 - 0.0061 16.2 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase DUF815 PF05673.8 EOO03202.1 - 0.009 14.9 0.1 0.25 10.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EOO03202.1 - 0.0099 16.0 0.0 7 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.7 EOO03202.1 - 0.015 14.6 0.0 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 EOO03202.1 - 0.016 14.7 0.2 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EOO03202.1 - 0.034 14.0 0.3 1.3 8.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EOO03202.1 - 0.038 13.7 0.2 7.7 6.3 0.1 3.0 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 EOO03202.1 - 0.042 13.7 3.1 11 6.0 0.0 3.8 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EOO03202.1 - 0.062 13.0 0.1 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 NTPase DEAD PF00270.24 EOO03202.1 - 0.071 12.5 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_14 PF13173.1 EOO03202.1 - 0.079 12.8 0.1 6.6 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 EOO03202.1 - 0.09 11.4 0.2 2.3 6.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 EOO03202.1 - 0.099 12.1 0.4 5.6 6.4 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EOO03202.1 - 0.11 12.0 0.4 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 EOO03202.1 - 0.16 10.5 0.1 4.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.17 EOO03202.1 - 0.2 10.4 0.2 7.2 5.3 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EOO03202.1 - 0.2 10.7 1.7 6.9 5.7 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA_15 PF13175.1 EOO03202.1 - 0.29 10.1 0.1 0.86 8.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EOO03202.1 - 0.32 9.9 0.1 22 3.9 0.0 2.2 2 0 0 2 2 2 0 Septin APS_kinase PF01583.15 EOO03202.1 - 0.49 10.0 4.7 11 5.6 0.0 3.6 4 0 0 4 4 4 0 Adenylylsulphate kinase Thioesterase PF00975.15 EOO03203.1 - 3.8e-20 73.0 0.0 2.6e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EOO03203.1 - 4.6e-08 33.2 0.1 5.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO03203.1 - 0.0004 20.1 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO03203.1 - 0.059 12.9 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EOO03203.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thiolase_C PF02803.13 EOO03204.1 - 2.8e-43 146.2 0.4 4.3e-43 145.6 0.3 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EOO03204.1 - 5.8e-29 100.8 0.1 8.4e-29 100.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain FTCD_C PF04961.7 EOO03204.1 - 2.6 7.4 6.1 0.24 10.7 0.3 2.0 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase His_Phos_2 PF00328.17 EOO03205.1 - 3.8e-09 36.3 0.2 8.9e-08 31.8 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) AOX PF01786.12 EOO03206.1 - 2.2e-86 288.5 0.0 2.7e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Rad60-SLD PF11976.3 EOO03207.1 - 8.1e-14 51.0 0.3 3.5e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EOO03207.1 - 2.6e-05 23.5 0.2 0.03 13.7 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin family eIF3_subunit PF08597.5 EOO03208.1 - 2.9e-67 226.7 24.5 3.3e-67 226.6 17.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit HAUS6_N PF14661.1 EOO03208.1 - 4.6 6.5 17.5 2.5 7.3 0.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus GAGA_bind PF06217.7 EOO03208.1 - 6.4 6.6 12.9 2.7 7.8 4.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Vpu PF00558.14 EOO03208.1 - 8.7 5.9 7.4 28 4.3 5.1 1.8 1 0 0 1 1 1 0 Vpu protein CFEM PF05730.6 EOO03209.1 - 2.1e-12 46.6 14.1 2.1e-12 46.6 9.8 1.7 2 0 0 2 2 2 1 CFEM domain Mucin PF01456.12 EOO03209.1 - 0.025 14.3 24.4 0.041 13.6 16.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 EOO03209.1 - 8.9 4.0 13.9 12 3.6 9.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short_C2 PF13561.1 EOO03210.1 - 2.6e-18 66.6 0.1 9.8e-14 51.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO03210.1 - 7.9e-14 51.9 2.1 6.5e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EOO03210.1 - 0.00015 21.5 0.3 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EOO03210.1 - 0.037 13.4 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-C2H2 PF00096.21 EOO03211.1 - 0.00012 22.1 0.5 0.6 10.5 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO03211.1 - 0.00029 20.9 0.9 0.92 9.9 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EOO03211.1 - 0.0024 18.0 0.3 0.029 14.6 0.1 2.5 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 EOO03211.1 - 1.9 8.2 3.8 0.54 9.9 0.4 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Cupin_2 PF07883.6 EOO03212.1 - 8.4e-15 54.0 0.1 1.5e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EOO03212.1 - 3.8e-07 29.6 0.0 5.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EOO03212.1 - 7.4e-06 25.2 0.1 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EOO03212.1 - 3.9e-05 23.3 0.3 7.9e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 EOO03212.1 - 7.1e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.3 EOO03212.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like MannoseP_isomer PF01050.13 EOO03212.1 - 0.0003 20.4 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase EutQ PF06249.7 EOO03212.1 - 0.00093 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ ARD PF03079.9 EOO03212.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family MFS_1 PF07690.11 EOO03213.1 - 3.3e-26 91.8 30.5 4.9e-26 91.2 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ResB PF05140.9 EOO03213.1 - 0.29 9.6 0.8 0.47 8.9 0.6 1.2 1 0 0 1 1 1 0 ResB-like family MDM31_MDM32 PF08118.6 EOO03216.1 - 1e-179 598.2 0.0 5.2e-179 595.8 0.0 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EOO03218.1 - 1.8e-05 24.3 0.7 4.2e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 KH domain Delta_lysin PF05372.6 EOO03219.1 - 0.049 12.9 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family UDG PF03167.14 EOO03220.1 - 1.4e-21 76.5 0.1 4.6e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily UDPGP PF01704.13 EOO03221.1 - 1e-50 172.4 0.0 1.4e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3827 PF12877.2 EOO03223.1 - 2.8 5.9 5.2 3.9 5.4 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) BUD22 PF09073.5 EOO03223.1 - 6.6 5.6 26.9 3.9 6.4 17.5 1.3 1 1 0 1 1 1 0 BUD22 LMBR1 PF04791.11 EOO03224.1 - 1.1e-15 57.1 4.8 1.1e-15 57.1 3.3 2.6 1 1 1 3 3 3 2 LMBR1-like membrane protein Mpv17_PMP22 PF04117.7 EOO03225.1 - 1.2e-26 92.0 1.4 2e-26 91.3 1.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family HET PF06985.6 EOO03226.1 - 1.4e-24 86.8 0.0 4.4e-24 85.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF883 PF05957.8 EOO03227.1 - 0.048 14.0 6.4 0.11 12.8 2.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EOO03227.1 - 0.08 13.3 8.9 0.084 13.2 0.6 2.5 1 1 1 2 2 2 0 YtxH-like protein CsbD PF05532.7 EOO03227.1 - 0.61 9.8 19.4 27 4.5 9.8 3.5 1 1 1 2 2 2 0 CsbD-like LEA_4 PF02987.11 EOO03227.1 - 2.2 8.2 13.1 0.66 9.8 5.3 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein CPSF_A PF03178.10 EOO03228.1 - 1.9e-62 211.1 0.0 2.8e-60 204.0 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region HAD_2 PF13419.1 EOO03229.1 - 5.5e-27 95.1 0.0 7.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EOO03229.1 - 0.016 15.6 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 EOO03230.1 - 5.3e-19 68.9 0.3 7.6e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO03230.1 - 3.1e-17 62.8 0.0 4.7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO03230.1 - 4e-10 38.8 0.0 8.2e-10 37.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EOO03230.1 - 9.7e-10 38.0 0.0 3.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EOO03230.1 - 9.6e-07 27.9 0.0 1.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EOO03230.1 - 0.0034 16.3 0.2 0.43 9.4 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EOO03230.1 - 0.014 14.3 0.1 0.05 12.5 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Epimerase_Csub PF13950.1 EOO03230.1 - 0.038 13.9 0.1 6 6.8 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit AlaDh_PNT_C PF01262.16 EOO03230.1 - 0.046 13.2 0.1 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SNAP PF14938.1 EOO03230.1 - 0.072 12.2 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ZZ PF00569.12 EOO03231.1 - 2.5e-10 39.7 7.1 4.4e-10 38.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EOO03231.1 - 2.6e-09 35.7 4.2 0.0007 18.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EOO03231.1 - 4.9e-07 29.7 3.7 2.5e-06 27.5 2.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EOO03231.1 - 7.9e-07 28.4 4.1 0.0015 18.2 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EOO03231.1 - 0.0005 19.6 2.8 0.64 9.6 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair C1_3 PF07649.7 EOO03231.1 - 0.021 14.8 5.8 0.039 14.0 4.0 1.5 1 0 0 1 1 1 0 C1-like domain DUF3591 PF12157.3 EOO03232.1 - 7.9e-174 578.3 0.1 1.4e-173 577.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 EOO03232.1 - 0.014 15.2 0.9 0.024 14.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EOO03232.1 - 0.12 12.0 1.8 0.28 10.8 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle ADP_ribosyl_GH PF03747.9 EOO03233.1 - 1.3e-65 222.0 0.4 1.4e-65 221.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pescadillo_N PF06732.6 EOO03234.1 - 3.8e-113 377.4 0.3 3.8e-113 377.4 0.2 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EOO03234.1 - 1.2e-09 38.2 0.0 5.5e-09 36.0 0.0 2.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Astro_capsid PF03115.9 EOO03234.1 - 2.7 6.1 7.1 4 5.5 5.0 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Tom37_C PF11801.3 EOO03235.1 - 1.3e-26 93.4 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EOO03235.1 - 4.9e-17 61.9 0.0 1.3e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EOO03235.1 - 0.0048 16.7 0.1 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EOO03235.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arginase PF00491.16 EOO03236.1 - 2.6e-43 148.2 0.1 3e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family PIG-U PF06728.8 EOO03237.1 - 2.6e-67 227.3 25.3 3e-67 227.1 17.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U zf-DHHC PF01529.15 EOO03238.1 - 3.6e-12 46.0 2.1 5.1e-12 45.5 1.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Nop25 PF09805.4 EOO03238.1 - 0.23 11.5 3.5 0.35 10.9 2.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) UPF0183 PF03676.9 EOO03239.1 - 9.9e-36 123.1 0.0 3e-23 82.0 0.0 4.9 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) FAD_binding_8 PF08022.7 EOO03240.1 - 9.2e-23 80.1 0.0 1.9e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EOO03240.1 - 3.1e-22 79.1 0.0 5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EOO03240.1 - 3.8e-18 65.7 10.4 3.8e-18 65.7 7.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EOO03240.1 - 2.9e-05 24.1 0.0 8.8e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EOO03240.1 - 0.15 12.6 0.0 2.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain p450 PF00067.17 EOO03241.1 - 1.4e-30 106.2 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRF-TF PF00319.13 EOO03242.1 - 2.6e-24 84.1 0.2 3.3e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Lactamase_B PF00753.22 EOO03243.1 - 5.5e-05 22.8 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.1 EOO03243.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DZR PF12773.2 EOO03243.1 - 0.032 14.0 0.6 0.058 13.2 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EOO03243.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Kinesin PF00225.18 EOO03244.1 - 2.3e-109 365.1 0.3 6.4e-109 363.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EOO03244.1 - 2.7e-05 24.3 0.6 2.7e-05 24.3 0.4 5.0 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding CIDE-N PF02017.10 EOO03244.1 - 0.073 12.8 3.7 0.65 9.8 0.5 2.7 2 0 0 2 2 2 0 CIDE-N domain Myosin_head PF00063.16 EOO03245.1 - 4.4e-228 758.7 7.3 7.1e-228 758.0 5.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EOO03245.1 - 4.7e-37 127.2 0.0 1.4e-36 125.6 0.0 1.8 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EOO03245.1 - 5.9e-13 47.9 0.3 1.1e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EOO03245.1 - 3.4e-12 45.7 0.2 1.2e-11 43.9 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EOO03245.1 - 9.7e-10 37.7 0.0 2.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 EOO03245.1 - 0.00099 18.5 9.8 0.034 13.7 1.6 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EOO03245.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain SH3_3 PF08239.6 EOO03245.1 - 0.0076 16.4 0.5 0.023 14.8 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.7 EOO03245.1 - 0.012 14.9 0.2 3.3 6.9 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 EOO03245.1 - 0.015 15.2 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Zeta_toxin PF06414.7 EOO03245.1 - 0.02 14.0 0.0 0.052 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EOO03245.1 - 0.02 15.7 0.1 0.082 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EOO03245.1 - 0.025 14.8 0.1 0.081 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF4145 PF13643.1 EOO03245.1 - 0.069 13.0 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) AAA_19 PF13245.1 EOO03245.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EOO03245.1 - 0.12 12.0 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Hexokinase_2 PF03727.11 EOO03246.1 - 1.1e-87 293.2 0.0 1.6e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EOO03246.1 - 1.6e-68 230.1 0.1 8.5e-65 217.9 0.0 3.1 2 1 0 2 2 2 2 Hexokinase MiAMP1 PF09117.5 EOO03246.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 MiAMP1 Pil1 PF13805.1 EOO03247.1 - 2.1e-105 351.7 4.7 3.1e-105 351.1 3.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 EOO03247.1 - 0.011 15.8 1.6 0.066 13.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) VTC PF09359.5 EOO03248.1 - 5.6e-101 337.2 0.8 7.8e-101 336.8 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EOO03248.1 - 7e-27 94.9 4.6 2.3e-14 53.8 0.3 3.1 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EOO03248.1 - 6.8e-14 51.8 3.2 1.6e-13 50.6 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.11 EOO03248.1 - 0.2 9.9 0.7 0.31 9.3 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Cys_Met_Meta_PP PF01053.15 EOO03249.1 - 1.7e-21 75.9 0.0 3.6e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EOO03249.1 - 5.7e-07 28.8 0.0 9.2e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Clat_adaptor_s PF01217.15 EOO03250.1 - 1.6e-16 60.2 0.0 7.4e-14 51.6 0.1 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Pkinase PF00069.20 EOO03251.1 - 4.2e-43 147.3 0.0 5.8e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03251.1 - 2.8e-32 111.8 0.0 4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO03251.1 - 0.00033 19.7 0.0 0.0006 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO03251.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribophorin_I PF04597.9 EOO03252.1 - 9.2e-152 505.4 0.1 1.1e-151 505.3 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I FAD_binding_3 PF01494.14 EOO03253.1 - 3.1e-19 69.2 0.0 1.7e-10 40.5 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain SE PF08491.5 EOO03253.1 - 0.0022 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Sua5_yciO_yrdC PF01300.13 EOO03254.1 - 9.4e-52 174.8 0.0 1.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EOO03254.1 - 6.5e-28 97.3 0.0 1.3e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding IFT20 PF14931.1 EOO03254.1 - 0.047 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 MCM PF00493.18 EOO03255.1 - 4.2e-140 466.2 0.1 5.9e-140 465.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EOO03255.1 - 5.6e-26 91.4 0.1 3.1e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EOO03255.1 - 1.4e-05 24.3 0.0 0.00043 19.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EOO03255.1 - 4.3e-05 23.2 0.1 0.00018 21.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EOO03255.1 - 0.0014 18.2 0.0 0.0055 16.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EOO03255.1 - 0.0022 16.7 0.9 0.0042 15.8 0.6 1.4 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.2 EOO03256.1 - 0.00011 22.5 0.0 0.00053 20.2 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) NotI PF12183.3 EOO03256.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI Complex1_49kDa PF00346.14 EOO03257.1 - 2.4e-134 446.5 0.0 3.1e-134 446.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3437 PF11919.3 EOO03258.1 - 8.5e-32 108.7 0.0 2.9e-31 107.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Arylsulfotran_2 PF14269.1 EOO03260.1 - 1.2e-54 185.5 0.0 2e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EOO03260.1 - 4.2e-14 51.9 0.1 3.7e-13 48.8 0.0 2.2 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) TFIIA PF03153.8 EOO03260.1 - 0.16 11.8 20.9 0.27 11.1 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EOO03260.1 - 2.5 6.2 30.8 3.6 5.6 21.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EOO03260.1 - 5.3 6.3 36.5 5 6.4 21.8 2.1 2 0 0 2 2 2 0 Vta1 like MFS_1 PF07690.11 EOO03261.1 - 3.6e-24 85.1 16.9 3.6e-24 85.1 11.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily SCIMP PF15050.1 EOO03261.1 - 0.16 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein Peptidase_M4_C PF02868.10 EOO03262.1 - 2.4e-44 150.9 0.1 8.1e-44 149.2 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 EOO03262.1 - 1.3e-25 90.2 5.0 2.5e-25 89.3 3.5 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Senescence PF06911.7 EOO03262.1 - 0.016 14.9 0.2 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Senescence-associated protein Peptidase_M13 PF01431.16 EOO03262.1 - 0.018 14.2 0.3 0.047 12.8 0.2 1.7 1 0 0 1 1 1 0 Peptidase family M13 BPL_N PF09825.4 EOO03263.1 - 1.5e-141 471.4 0.0 1.8e-141 471.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EOO03263.1 - 3.5e-19 69.0 0.0 5.9e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family p450 PF00067.17 EOO03264.1 - 4.4e-42 144.1 0.2 4.1e-29 101.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Glyco_transf_92 PF01697.22 EOO03265.1 - 2.3e-06 27.1 1.0 3.1e-06 26.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EOO03265.1 - 0.00047 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 EOO03265.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 YkyB PF14177.1 EOO03265.1 - 0.073 13.2 0.0 0.26 11.4 0.0 1.8 1 1 1 2 2 2 0 YkyB-like protein p450 PF00067.17 EOO03266.1 - 9.3e-40 136.5 0.0 1.2e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gpi16 PF04113.9 EOO03267.1 - 2.6e-194 646.3 0.0 3.3e-194 646.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component zf-C2H2 PF00096.21 EOO03268.1 - 0.65 10.4 4.4 0.16 12.3 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO03268.1 - 0.92 9.9 3.9 7.1 7.2 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ADH_N PF08240.7 EOO03269.1 - 9e-18 64.0 0.0 2.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03269.1 - 1.1e-07 31.4 0.0 2e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EOO03269.1 - 0.0048 15.4 0.0 0.0074 14.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Fringe PF02434.11 EOO03270.1 - 1.4e-09 37.5 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EOO03270.1 - 9.1e-09 34.9 0.4 3.4e-08 33.0 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function, DUF604 Hyaluronidase_1 PF07212.6 EOO03270.1 - 0.11 11.4 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Hyaluronidase protein (HylP) FMO-like PF00743.14 EOO03271.1 - 1.1e-23 83.3 0.0 1.7e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EOO03271.1 - 3.7e-12 46.7 0.1 9.8e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EOO03271.1 - 8e-05 21.7 0.2 0.00021 20.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EOO03271.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EOO03271.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EOO03272.1 - 1.6e-21 76.7 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO03272.1 - 1.6e-08 33.8 0.5 0.00012 21.1 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EOO03272.1 - 5.4e-06 26.7 0.4 0.0055 17.0 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EOO03272.1 - 0.0016 18.3 0.8 0.021 14.6 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO03272.1 - 0.0018 17.1 0.1 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EOO03272.1 - 0.044 12.8 1.3 0.074 12.1 0.3 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO03272.1 - 0.082 12.9 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LUC7 PF03194.10 EOO03273.1 - 3.7e-70 236.3 0.1 4.6e-70 236.0 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus zf-C4H2 PF10146.4 EOO03273.1 - 0.1 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4164 PF13747.1 EOO03274.1 - 2.6e-05 24.2 21.1 0.19 11.8 2.6 3.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) AAA_27 PF13514.1 EOO03274.1 - 0.0005 17.9 12.5 0.00057 17.7 8.7 1.1 1 0 0 1 1 1 1 AAA domain WEMBL PF05701.6 EOO03274.1 - 0.00077 18.0 13.6 0.0013 17.2 9.4 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tricorn_C1 PF14684.1 EOO03274.1 - 0.0024 17.6 0.2 0.0045 16.8 0.1 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Sec2p PF06428.6 EOO03274.1 - 0.0026 17.5 2.2 0.0026 17.5 1.5 2.6 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p AAA_13 PF13166.1 EOO03274.1 - 0.0073 14.8 11.7 0.011 14.1 8.1 1.3 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EOO03274.1 - 0.0081 15.6 16.8 0.12 11.7 1.0 2.1 1 1 1 2 2 2 2 Intermediate filament protein GAS PF13851.1 EOO03274.1 - 0.011 14.9 22.6 0.18 11.0 9.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding tRNA-synt_1 PF00133.17 EOO03274.1 - 0.035 12.1 3.5 0.039 11.9 2.4 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) DUF4094 PF13334.1 EOO03274.1 - 0.041 14.2 10.5 0.16 12.4 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Carbpep_Y_N PF05388.6 EOO03274.1 - 0.053 13.6 0.8 0.053 13.6 0.5 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide ADIP PF11559.3 EOO03274.1 - 0.054 13.3 14.6 0.36 10.7 6.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EOO03274.1 - 0.073 12.6 22.5 0.076 12.6 3.0 2.2 1 1 1 2 2 2 0 IncA protein Spectrin PF00435.16 EOO03274.1 - 0.13 12.5 16.9 0.47 10.7 4.3 2.3 1 1 1 2 2 2 0 Spectrin repeat THOC7 PF05615.8 EOO03274.1 - 0.13 12.5 15.3 1.1 9.5 5.6 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Cluap1 PF10234.4 EOO03274.1 - 0.18 11.0 16.2 0.4 9.8 2.9 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Lyase_8_N PF08124.6 EOO03274.1 - 0.22 10.3 7.4 0.32 9.8 5.1 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Laminin_II PF06009.7 EOO03274.1 - 0.24 11.1 9.2 3.3 7.4 2.9 2.3 2 0 0 2 2 2 0 Laminin Domain II tRNA-synt_His PF13393.1 EOO03274.1 - 0.28 10.1 4.1 0.32 10.0 2.4 1.4 1 1 0 1 1 1 0 Histidyl-tRNA synthetase CENP-F_leu_zip PF10473.4 EOO03274.1 - 0.3 10.9 24.1 0.55 10.0 9.4 2.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.1 EOO03274.1 - 0.31 10.7 5.9 0.55 9.8 3.9 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Vps5 PF09325.5 EOO03274.1 - 0.36 10.0 16.4 1.7 7.8 2.4 2.2 1 1 1 2 2 2 0 Vps5 C terminal like Occludin_ELL PF07303.8 EOO03274.1 - 0.37 11.5 15.2 0.24 12.1 5.4 2.9 1 1 2 3 3 3 0 Occludin homology domain DUF3829 PF12889.2 EOO03274.1 - 0.41 9.7 17.0 4.7 6.3 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3086 PF11285.3 EOO03274.1 - 0.44 9.3 9.1 0.74 8.5 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Baculo_PEP_C PF04513.7 EOO03274.1 - 0.45 10.3 3.4 5.7 6.7 1.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3573 PF12097.3 EOO03274.1 - 0.48 8.9 3.5 0.56 8.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Reo_sigmaC PF04582.7 EOO03274.1 - 0.5 9.4 3.8 1.3 8.1 0.6 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein LEA_1 PF03760.10 EOO03274.1 - 0.53 10.4 7.1 1.9 8.6 0.4 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 DUF4200 PF13863.1 EOO03274.1 - 0.58 10.1 24.1 1.9 8.4 4.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Ead_Ea22 PF13935.1 EOO03274.1 - 0.64 10.3 14.6 0.037 14.3 3.9 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein Uso1_p115_C PF04871.8 EOO03274.1 - 0.66 9.8 25.7 0.073 13.0 8.9 2.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.10 EOO03274.1 - 0.69 9.9 15.4 0.39 10.7 7.7 2.1 1 1 1 2 2 2 0 Fez1 Mnd1 PF03962.10 EOO03274.1 - 0.78 9.3 20.7 1.3 8.6 1.9 2.2 1 1 1 2 2 2 0 Mnd1 family DUF745 PF05335.8 EOO03274.1 - 0.88 9.0 7.0 0.93 8.9 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) APG6 PF04111.7 EOO03274.1 - 0.93 8.4 22.3 6 5.8 8.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Sipho_Gp157 PF05565.6 EOO03274.1 - 1.1 8.8 21.9 3 7.4 5.3 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 XhlA PF10779.4 EOO03274.1 - 1.2 9.1 28.4 0.54 10.2 2.2 3.4 2 1 1 3 3 3 0 Haemolysin XhlA Ribosomal_L18_c PF14204.1 EOO03274.1 - 1.5 9.4 9.2 0.13 12.8 1.8 2.1 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region Tropomyosin_1 PF12718.2 EOO03274.1 - 1.6 8.5 26.5 34 4.2 17.2 2.2 1 1 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 EOO03274.1 - 2.1 8.1 23.8 0.92 9.2 3.0 3.3 2 1 1 3 3 3 0 Prefoldin subunit P30 PF07390.6 EOO03274.1 - 2.3 7.6 10.0 0.72 9.3 5.2 1.5 1 1 0 1 1 1 0 Mycoplasma P30 protein TPR_MLP1_2 PF07926.7 EOO03274.1 - 2.8 7.6 21.2 12 5.6 14.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF964 PF06133.6 EOO03274.1 - 2.9 7.9 13.9 0.82 9.7 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Atg14 PF10186.4 EOO03274.1 - 2.9 6.7 19.3 26 3.6 1.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF730 PF05325.6 EOO03274.1 - 3.3 7.5 7.8 13 5.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF4140 PF13600.1 EOO03274.1 - 5.4 7.5 16.0 22 5.5 0.7 3.8 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 EOO03274.1 - 6 6.7 16.6 4.5 7.1 7.9 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Med4 PF10018.4 EOO03274.1 - 7 6.0 18.9 8.3 5.7 3.0 3.6 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 GrpE PF01025.14 EOO03274.1 - 7 6.1 17.0 81 2.7 11.8 2.4 1 1 0 1 1 1 0 GrpE DUF342 PF03961.8 EOO03274.1 - 7.1 4.9 19.5 0.25 9.7 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF724 PF05266.9 EOO03274.1 - 7.3 6.1 21.2 2.9 7.4 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Bap31 PF05529.7 EOO03274.1 - 7.3 5.9 14.6 3.8 6.9 0.9 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Fib_alpha PF08702.5 EOO03274.1 - 7.8 6.6 14.2 4 7.5 3.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 EOO03274.1 - 7.8 6.4 17.6 2.4 8.1 3.6 2.8 1 1 2 3 3 3 0 FlxA-like protein DUF607 PF04678.8 EOO03274.1 - 8.9 6.1 11.1 8.9e+02 -0.4 7.7 2.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Asparaginase_2 PF01112.13 EOO03275.1 - 2.4e-41 141.5 0.3 1.1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Asparaginase Glyco_hydro_43 PF04616.9 EOO03276.1 - 2.3e-49 168.0 6.7 3.1e-49 167.6 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.6 EOO03276.1 - 2.3e-05 24.3 0.3 4.4e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) CBM_4_9 PF02018.12 EOO03276.1 - 0.0095 15.9 1.2 0.17 11.9 0.2 2.6 2 0 0 2 2 2 1 Carbohydrate binding domain DUF1412 PF07203.6 EOO03276.1 - 0.66 9.9 3.6 2.4 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) Tim17 PF02466.14 EOO03277.1 - 1.1e-34 119.2 6.8 1.3e-34 118.9 4.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 EOO03278.1 - 3.1e-76 256.7 28.3 3.5e-76 256.6 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03278.1 - 6e-17 61.3 18.3 6e-17 61.3 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EOO03278.1 - 0.73 9.8 9.0 0.12 12.3 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EOO03279.1 - 9.4e-43 146.2 59.2 4.1e-41 140.8 41.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO03279.1 - 6.4e-12 44.4 31.7 2.6e-11 42.4 20.5 2.2 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EOO03279.1 - 1.8e-08 33.4 16.8 1.8e-08 33.4 11.7 3.0 1 1 1 2 2 2 1 Sugar (and other) transporter AA_permease_2 PF13520.1 EOO03280.1 - 7.7e-21 74.1 37.1 9.1e-21 73.8 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO03280.1 - 4.7e-08 31.7 28.0 6.2e-08 31.4 19.4 1.1 1 0 0 1 1 1 1 Amino acid permease Tfb2 PF03849.9 EOO03281.1 - 1e-137 458.7 0.0 1.5e-137 458.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EOO03281.1 - 5.5e-06 26.1 0.0 4.8e-05 23.1 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Yip1 PF04893.12 EOO03282.1 - 2.8e-07 30.2 11.1 4.4e-05 23.0 4.1 2.4 2 1 0 2 2 2 2 Yip1 domain ADH_zinc_N PF00107.21 EOO03283.1 - 2.3e-10 40.1 0.0 4.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03283.1 - 0.0064 17.3 0.0 0.024 15.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO03283.1 - 0.012 15.3 0.0 0.066 12.9 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain AAA PF00004.24 EOO03284.1 - 1.6e-18 67.1 0.0 3.1e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EOO03284.1 - 8.3e-05 23.4 1.7 0.00061 20.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 EOO03284.1 - 0.00018 21.6 0.1 0.0013 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EOO03284.1 - 0.00025 20.8 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EOO03284.1 - 0.00031 20.7 0.0 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EOO03284.1 - 0.0004 20.6 0.1 0.0033 17.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EOO03284.1 - 0.00075 19.1 0.3 0.0018 18.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 EOO03284.1 - 0.00093 18.7 0.1 0.026 13.9 0.1 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 EOO03284.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EOO03284.1 - 0.017 15.0 0.2 0.099 12.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.12 EOO03284.1 - 0.027 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EOO03284.1 - 0.03 13.2 0.0 0.085 11.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_2 PF07724.9 EOO03284.1 - 0.032 14.1 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EOO03284.1 - 0.037 13.1 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EOO03284.1 - 0.037 13.4 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EOO03284.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EOO03284.1 - 0.054 13.3 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EOO03284.1 - 0.081 12.0 0.2 0.26 10.3 0.1 1.8 1 1 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 EOO03284.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_M66 PF10462.4 EOO03285.1 - 2.3e-05 23.4 0.7 4.1e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase M66 BiPBP_C PF06832.7 EOO03285.1 - 0.0001 22.1 0.0 0.00034 20.4 0.0 1.9 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family Reprolysin_2 PF13574.1 EOO03285.1 - 0.0043 17.1 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EOO03285.1 - 0.0059 16.5 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EOO03285.1 - 0.037 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like P12 PF12669.2 EOO03285.1 - 0.055 13.6 2.6 0.13 12.4 1.8 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family BNR PF02012.15 EOO03285.1 - 0.11 12.4 0.6 0.4 10.6 0.4 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Reprolysin_3 PF13582.1 EOO03285.1 - 1.4 9.4 7.7 0.094 13.2 1.1 2.4 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like TB2_DP1_HVA22 PF03134.14 EOO03286.1 - 2.1e-29 101.0 8.2 3.2e-29 100.5 5.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sugar_tr PF00083.19 EOO03287.1 - 8.8e-73 245.3 30.3 1e-72 245.1 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03287.1 - 4.1e-15 55.3 49.8 3.8e-12 45.5 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 EOO03287.1 - 0.0021 18.3 3.2 0.0021 18.3 2.2 2.8 2 1 1 3 3 3 1 Divalent cation transporter ADH_N PF08240.7 EOO03288.1 - 3.7e-21 74.9 6.2 8e-21 73.8 4.3 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03288.1 - 1.7e-19 69.6 0.0 2.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03288.1 - 1.9e-06 28.8 0.0 3.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EOO03288.1 - 0.00044 19.4 0.4 0.0007 18.7 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EOO03288.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Complex1_LYR PF05347.10 EOO03289.1 - 7e-12 44.9 0.0 5.6e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) UQ_con PF00179.21 EOO03289.1 - 7.8e-11 41.5 0.0 7.8e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Complex1_LYR_1 PF13232.1 EOO03289.1 - 1.4e-10 41.2 0.0 7.2e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Complex1_LYR-like RWD PF05773.17 EOO03289.1 - 0.026 14.4 2.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 0 RWD domain Plug_translocon PF10559.4 EOO03289.1 - 0.11 12.0 0.2 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Plug domain of Sec61p DUF1615 PF07759.7 EOO03289.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) RCC1 PF00415.13 EOO03290.1 - 6.9e-62 205.4 0.0 7.6e-12 45.2 0.0 7.8 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EOO03290.1 - 2e-43 145.1 12.8 2.6e-10 39.6 0.0 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EOO03290.1 - 0.013 14.9 0.0 5.1 6.6 0.0 2.9 2 0 0 2 2 2 0 Putative carbohydrate binding domain Nucleoporin_N PF08801.6 EOO03290.1 - 0.013 14.2 0.5 0.41 9.3 0.0 3.2 3 1 0 3 3 3 0 Nup133 N terminal like DAO PF01266.19 EOO03291.1 - 7.5e-57 192.8 0.7 9e-57 192.5 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO03291.1 - 2.1e-05 24.6 0.2 0.0011 19.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO03291.1 - 0.0029 17.5 0.1 0.0029 17.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EOO03291.1 - 0.012 15.3 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EOO03291.1 - 0.03 13.2 0.1 0.063 12.1 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EOO03291.1 - 0.52 9.1 11.2 0.0074 15.1 0.9 2.4 2 1 0 2 2 2 0 FAD binding domain VIT1 PF01988.14 EOO03292.1 - 6.9e-72 241.3 2.6 7.9e-72 241.1 1.8 1.0 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 EOO03292.1 - 0.11 11.7 4.0 0.067 12.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Orai-1 PF07856.7 EOO03292.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity GlpM PF06942.7 EOO03292.1 - 0.27 11.5 4.7 1 9.6 0.2 3.0 3 1 0 3 3 3 0 GlpM protein DUF3159 PF11361.3 EOO03292.1 - 0.72 9.2 6.4 1.2 8.5 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3159) p450 PF00067.17 EOO03293.1 - 4.1e-35 121.1 0.0 4.7e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Crystall_3 PF08964.5 EOO03294.1 - 0.00014 21.4 0.1 0.00047 19.8 0.0 1.8 1 1 1 2 2 2 1 Beta/Gamma crystallin PAN_2 PF08276.6 EOO03294.1 - 0.017 14.9 1.8 0.024 14.4 1.3 1.3 1 0 0 1 1 1 0 PAN-like domain DUF4189 PF13827.1 EOO03294.1 - 0.2 11.9 3.0 0.38 11.0 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) BetaGal_dom2 PF10435.4 EOO03295.1 - 6.9e-64 214.5 2.4 8.5e-64 214.2 1.6 1.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Glyco_hydro_35 PF01301.14 EOO03295.1 - 3e-20 72.8 0.2 4.4e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 DHDPS PF00701.17 EOO03296.1 - 1.9e-46 157.9 0.0 2.6e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_5 PF12695.2 EOO03297.1 - 0.00026 20.7 0.1 0.00055 19.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EOO03297.1 - 0.0005 19.3 0.0 0.0008 18.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EOO03297.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EOO03297.1 - 0.0031 16.0 0.0 0.015 13.8 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EOO03297.1 - 0.0041 16.3 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 EOO03297.1 - 0.04 13.3 0.1 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 EOO03298.1 - 4.1e-15 56.2 3.4 2e-14 54.0 1.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO03298.1 - 2e-13 50.3 0.3 7.4e-13 48.4 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EOO03298.1 - 5.9e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EOO03298.1 - 0.00018 21.1 0.1 0.00034 20.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EOO03298.1 - 0.00051 19.5 0.8 0.0035 16.8 0.0 2.5 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EOO03298.1 - 0.0019 17.7 0.1 0.0053 16.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EOO03298.1 - 0.0027 17.1 0.3 0.017 14.5 0.2 2.1 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EOO03298.1 - 0.0056 15.2 0.1 0.0089 14.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 EOO03298.1 - 0.038 12.4 0.0 0.067 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PAF-AH_p_II PF03403.8 EOO03298.1 - 0.045 12.0 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 EOO03298.1 - 0.086 11.7 0.1 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase enzyme Ank_2 PF12796.2 EOO03299.1 - 2.8e-71 235.9 11.1 1e-17 64.2 0.1 5.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EOO03299.1 - 9.1e-69 224.0 10.2 1.3e-09 37.4 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 EOO03299.1 - 2.8e-52 169.4 5.6 3e-06 26.9 0.0 9.5 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 EOO03299.1 - 1.5e-50 168.0 13.2 8.1e-11 41.8 0.0 6.2 1 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO03299.1 - 2.2e-50 168.1 6.2 2.5e-09 37.3 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) OPT PF03169.10 EOO03300.1 - 1.9e-86 290.9 19.2 3.9e-75 253.5 8.0 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Methyltransf_23 PF13489.1 EOO03301.1 - 3.9e-14 52.6 0.0 6.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03301.1 - 3.9e-09 36.8 0.0 9.3e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03301.1 - 2.1e-07 31.3 0.0 1.3e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03301.1 - 4.2e-05 23.1 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EOO03301.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EOO03301.1 - 0.007 16.9 0.0 0.022 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03301.1 - 0.034 14.5 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Band_7 PF01145.20 EOO03302.1 - 7.1e-31 107.4 0.9 1.4e-30 106.5 0.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EOO03302.1 - 0.052 13.0 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family UPF0075 PF03702.9 EOO03303.1 - 3.1e-76 256.6 0.0 5.4e-58 196.6 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0075) Glyco_hydro_10 PF00331.15 EOO03304.1 - 3.7e-102 341.6 0.6 4.5e-102 341.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Frankia_peptide PF14407.1 EOO03304.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. ABC_tran PF00005.22 EOO03305.1 - 7.5e-11 42.4 0.0 6.6e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.14 EOO03305.1 - 1.4e-05 24.4 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EOO03305.1 - 0.013 15.5 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4185 PF13810.1 EOO03306.1 - 1.7e-09 37.0 6.6 2.3e-09 36.5 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Kelch_5 PF13854.1 EOO03306.1 - 0.12 12.3 1.1 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Kelch motif ADH_N PF08240.7 EOO03307.1 - 3.5e-27 94.3 0.2 6.8e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03307.1 - 6.9e-14 51.5 0.1 1.6e-13 50.2 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EOO03307.1 - 0.0089 16.1 0.1 0.043 13.9 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EOO03307.1 - 0.023 14.4 0.3 0.054 13.3 0.2 1.6 1 1 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 EOO03307.1 - 0.031 14.3 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 EOO03307.1 - 0.041 14.4 0.1 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EOO03307.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NACHT PF05729.7 EOO03308.1 - 1.3e-13 50.9 0.1 2.7e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EOO03308.1 - 2.8e-06 27.4 0.3 2.8e-06 27.4 0.2 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EOO03308.1 - 3e-05 24.1 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AFG1_ATPase PF03969.11 EOO03308.1 - 0.003 16.4 0.0 0.0079 15.0 0.0 1.7 1 0 0 1 1 1 1 AFG1-like ATPase Arch_ATPase PF01637.13 EOO03308.1 - 0.0033 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EOO03308.1 - 0.0033 16.4 0.0 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EOO03308.1 - 0.02 13.7 0.7 0.042 12.7 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain KAP_NTPase PF07693.9 EOO03308.1 - 0.024 13.6 1.2 0.13 11.2 0.1 2.5 2 1 1 3 3 3 0 KAP family P-loop domain Latarcin PF10279.4 EOO03308.1 - 0.024 14.8 0.5 0.13 12.4 0.1 2.4 2 0 0 2 2 2 0 Latarcin precursor DDHD PF02862.12 EOO03308.1 - 0.034 13.9 0.3 0.083 12.6 0.2 1.5 1 0 0 1 1 1 0 DDHD domain UPF0079 PF02367.12 EOO03308.1 - 0.061 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EOO03308.1 - 0.075 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CHB_HEX_C PF03174.8 EOO03310.1 - 2.3e-12 46.5 10.6 6.3e-12 45.1 4.0 3.1 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 EOO03310.1 - 3e-12 46.4 10.6 5.7e-12 45.5 4.0 2.7 2 0 0 2 2 2 1 Fn3 associated CHB_HEX_C_1 PF13290.1 EOO03310.1 - 5e-11 42.2 11.2 6.4e-11 41.8 3.4 3.0 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain F5_F8_type_C PF00754.20 EOO03310.1 - 1.2e-08 34.7 2.1 5e-08 32.8 0.5 2.7 2 1 1 3 3 3 1 F5/8 type C domain Beta-lactamase PF00144.19 EOO03311.1 - 1.2e-10 40.9 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Esterase_phd PF10503.4 EOO03312.1 - 1.4e-19 70.2 0.3 2.7e-19 69.2 0.2 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EOO03312.1 - 4.6e-13 48.8 0.7 6.7e-13 48.3 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EOO03312.1 - 0.00061 18.6 0.5 0.00081 18.2 0.4 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EOO03312.1 - 0.0022 17.7 0.2 0.0032 17.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EOO03312.1 - 0.008 16.0 0.0 0.032 14.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EOO03312.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SoxZ PF08770.6 EOO03313.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ MFS_1 PF07690.11 EOO03313.1 - 0.41 9.3 8.5 0.37 9.4 5.0 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily AA_permease PF00324.16 EOO03314.1 - 5.9e-109 364.5 47.2 7.2e-109 364.2 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO03314.1 - 9.8e-30 103.4 49.3 1.2e-29 103.1 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pec_lyase_C PF00544.14 EOO03315.1 - 4.4e-45 153.6 7.2 6e-45 153.1 5.0 1.2 1 0 0 1 1 1 1 Pectate lyase NAD_binding_10 PF13460.1 EOO03316.1 - 9.9e-17 61.5 0.5 1.3e-16 61.0 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO03316.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EOO03316.1 - 2.1e-08 33.7 0.3 4.8e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EOO03316.1 - 6.8e-06 24.9 0.0 0.019 13.6 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EOO03316.1 - 0.00016 20.6 0.1 0.00043 19.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EOO03316.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Gly-zipper_YMGG PF13441.1 EOO03316.1 - 0.039 13.4 0.9 0.039 13.4 0.6 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper TrkA_N PF02254.13 EOO03316.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Gly-zipper_Omp PF13488.1 EOO03316.1 - 3.1 7.5 8.0 0.15 11.7 1.0 2.1 2 0 0 2 2 2 0 Glycine zipper p450 PF00067.17 EOO03317.1 - 2.6e-76 257.0 0.0 3e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EOO03318.1 - 1e-21 77.6 0.3 1.4e-21 77.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03318.1 - 7.7e-09 35.4 0.1 1.1e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO03318.1 - 2.9e-06 27.2 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EOO03318.1 - 0.03 14.1 0.2 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PI-PLC-X PF00388.14 EOO03320.1 - 6.4e-47 158.6 0.0 9.5e-47 158.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EOO03320.1 - 1.3e-30 105.7 0.0 2.4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain YL1 PF05764.8 EOO03320.1 - 0.0078 15.8 1.0 0.012 15.2 0.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.7 EOO03320.1 - 0.036 12.4 3.6 0.053 11.9 2.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) C2 PF00168.25 EOO03320.1 - 0.13 12.0 0.8 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 C2 domain CENP-B_dimeris PF09026.5 EOO03320.1 - 1.4 9.2 8.0 0.078 13.2 1.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain adh_short PF00106.20 EOO03321.1 - 2.9e-21 76.0 2.1 4.1e-21 75.5 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03321.1 - 3.3e-17 63.0 0.6 5.5e-17 62.3 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EOO03321.1 - 1e-07 31.4 0.0 2.8e-06 26.7 0.1 2.1 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EOO03321.1 - 1.1e-05 24.8 0.1 3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EOO03321.1 - 7.6e-05 22.7 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EOO03321.1 - 0.00033 20.5 0.1 0.00071 19.4 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EOO03321.1 - 0.0023 17.6 0.4 0.0041 16.7 0.3 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 EOO03321.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.21 EOO03321.1 - 0.013 15.0 0.2 0.031 13.8 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 EOO03321.1 - 0.014 15.7 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EOO03321.1 - 0.018 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Toluene_X PF03349.11 EOO03321.1 - 0.033 12.5 0.4 0.047 12.0 0.3 1.1 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) RmlD_sub_bind PF04321.12 EOO03321.1 - 0.071 11.9 0.2 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EOO03321.1 - 0.094 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.16 EOO03321.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NRDE PF05742.7 EOO03323.1 - 6.9e-42 143.6 0.1 1e-30 106.9 0.0 2.4 2 1 0 2 2 2 2 NRDE protein 2OG-FeII_Oxy PF03171.15 EOO03324.1 - 6.7e-21 74.4 0.0 8.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_47 PF01532.15 EOO03325.1 - 6.2e-167 555.8 0.0 7e-167 555.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 EOO03325.1 - 0.034 13.1 0.1 5.4 5.9 0.0 2.6 3 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EOO03325.1 - 0.09 11.0 0.0 1.4 7.0 0.0 2.5 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) dCMP_cyt_deam_1 PF00383.17 EOO03326.1 - 4e-08 32.8 0.0 6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EOO03326.1 - 0.069 12.9 0.2 0.75 9.6 0.1 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase p450 PF00067.17 EOO03327.1 - 6.2e-29 100.8 0.0 7.6e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PaaSYMP PF14738.1 EOO03327.1 - 0.097 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Miro PF08477.8 EOO03327.1 - 0.11 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein AA_permease PF00324.16 EOO03328.1 - 2.4e-92 309.7 30.7 2.8e-92 309.5 21.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO03328.1 - 5.8e-33 114.0 31.1 7.1e-33 113.7 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease Macro PF01661.16 EOO03329.1 - 2.1e-07 30.8 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Macro domain bZIP_1 PF00170.16 EOO03330.1 - 3.1e-06 27.0 6.8 6.9e-06 25.9 4.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor Pox_A22 PF04848.8 EOO03330.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A22 protein AT_hook PF02178.14 EOO03330.1 - 2.1 8.2 6.1 2.4 8.0 0.7 2.8 2 0 0 2 2 2 0 AT hook motif 4HBT PF03061.17 EOO03331.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HgmA PF04209.8 EOO03332.1 - 4.2e-125 417.4 0.0 4.7e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thymidylat_synt PF00303.14 EOO03333.1 - 4.9e-115 383.1 0.0 5.5e-115 382.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Aldolase_II PF00596.16 EOO03334.1 - 4e-47 160.1 0.0 5.1e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 EOO03335.1 - 9.3e-27 93.6 36.8 2.8e-26 92.0 25.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.6 EOO03335.1 - 1.7 7.9 4.3 0.65 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) UPF0075 PF03702.9 EOO03336.1 - 9.2e-74 248.5 0.0 1e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) AMP-binding PF00501.23 EOO03337.1 - 1.7e-79 267.1 0.0 6.7e-79 265.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EOO03337.1 - 8.3e-76 254.8 0.0 1.7e-75 253.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EOO03337.1 - 1.1e-49 169.2 0.7 1.9e-49 168.3 0.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EOO03337.1 - 1.2e-49 168.7 0.0 1.9e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EOO03337.1 - 8.2e-49 165.7 0.1 2.3e-47 160.9 0.0 2.9 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EOO03337.1 - 3e-41 141.1 0.0 4e-38 130.9 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EOO03337.1 - 4.7e-38 131.2 0.0 8.4e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EOO03337.1 - 8.2e-35 119.9 0.0 1.1e-33 116.2 0.0 2.8 3 1 0 3 3 2 1 Male sterility protein Methyltransf_12 PF08242.7 EOO03337.1 - 9.3e-19 67.7 0.0 2.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EOO03337.1 - 1.3e-17 63.8 1.1 1.4e-07 31.6 0.0 4.3 4 0 0 4 4 4 2 Phosphopantetheine attachment site Epimerase PF01370.16 EOO03337.1 - 1.2e-13 51.0 0.0 3.8e-11 42.8 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 EOO03337.1 - 1.4e-13 51.1 0.0 3.9e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03337.1 - 1.6e-13 50.4 0.0 4.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 EOO03337.1 - 2.1e-12 46.9 0.3 1.4e-05 24.9 0.2 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 EOO03337.1 - 1.3e-09 37.9 0.0 8.3e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03337.1 - 1.4e-09 38.5 0.1 1e-08 35.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 EOO03337.1 - 3.2e-09 36.9 0.1 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EOO03337.1 - 4.6e-05 22.6 0.0 9.2e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EOO03337.1 - 0.00076 18.5 0.0 0.0019 17.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain NodS PF05401.6 EOO03337.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) 3Beta_HSD PF01073.14 EOO03337.1 - 0.016 13.9 0.0 0.092 11.4 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 EOO03337.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Polysacc_synt_2 PF02719.10 EOO03337.1 - 1.6 7.5 0.0 50 2.6 0.0 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Pox_MCEL PF03291.11 EOO03337.1 - 5.3 5.8 0.0 9.6 4.9 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme NmrA PF05368.8 EOO03338.1 - 3.2e-31 108.3 0.0 5.7e-31 107.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO03338.1 - 4.3e-09 36.6 0.1 6.2e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EOO03338.1 - 0.0042 17.3 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EOO03338.1 - 0.0048 16.8 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EOO03338.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EOO03338.1 - 0.028 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EOO03338.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EOO03339.1 - 1.5e-74 251.2 9.0 1.8e-74 250.9 6.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03339.1 - 2.7e-29 102.0 39.7 1.5e-23 83.0 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_assoc PF09775.4 EOO03339.1 - 0.034 13.6 0.1 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Ank_2 PF12796.2 EOO03340.1 - 1.5e-88 291.2 0.0 1.5e-12 47.6 0.0 7.6 4 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EOO03340.1 - 2.3e-58 191.2 0.2 0.00057 19.5 0.0 16.3 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 EOO03340.1 - 3.3e-45 151.7 0.8 2.4e-07 31.0 0.0 12.2 6 3 8 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO03340.1 - 4.4e-42 141.1 0.1 2.4e-05 24.4 0.0 11.1 5 4 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO03340.1 - 1.4e-41 136.3 0.0 0.17 12.1 0.0 15.2 16 0 0 16 16 16 12 Ankyrin repeat TMF_DNA_bd PF12329.3 EOO03342.1 - 0.0013 18.5 2.4 0.0018 18.0 1.7 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 EOO03342.1 - 0.0057 17.0 0.9 0.055 13.9 0.2 2.1 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF1465 PF07323.7 EOO03342.1 - 0.0064 16.0 0.2 0.0091 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) Lebercilin PF15619.1 EOO03342.1 - 0.017 14.5 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.7 EOO03342.1 - 0.022 12.9 0.3 0.028 12.6 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EOO03342.1 - 0.028 13.5 1.5 0.037 13.1 1.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3972 PF13118.1 EOO03342.1 - 0.035 14.1 1.1 0.056 13.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF2203 PF09969.4 EOO03342.1 - 0.036 14.2 0.3 0.059 13.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.3 EOO03342.1 - 0.051 13.3 0.5 0.081 12.6 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Lzipper-MIP1 PF14389.1 EOO03342.1 - 0.055 13.5 0.6 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 RRF PF01765.14 EOO03342.1 - 0.075 12.4 1.1 0.12 11.8 0.4 1.6 1 1 1 2 2 2 0 Ribosome recycling factor Baculo_PEP_C PF04513.7 EOO03342.1 - 0.077 12.8 1.0 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EOO03342.1 - 0.11 12.1 1.0 0.19 11.3 0.7 1.5 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EOO03342.1 - 0.16 11.8 4.1 0.53 10.1 2.8 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Asp PF00026.18 EOO03343.1 - 4.7e-77 259.3 15.6 5.6e-77 259.0 10.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO03343.1 - 1e-08 35.3 5.2 1.6e-08 34.6 1.4 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO03343.1 - 0.00091 19.6 2.2 0.7 10.4 0.3 3.1 2 1 0 2 2 2 2 Aspartyl protease Transp_cyt_pur PF02133.10 EOO03344.1 - 2.4e-54 184.5 30.7 2.9e-54 184.2 21.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF962 PF06127.6 EOO03344.1 - 0.12 12.2 1.7 0.31 10.9 0.0 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF962) MR_MLE_C PF13378.1 EOO03345.1 - 1.7e-32 111.6 0.2 1.6e-31 108.5 0.0 2.4 2 1 1 3 3 3 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EOO03345.1 - 1.9e-20 73.0 0.0 4.1e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EOO03345.1 - 3.2e-09 37.1 0.1 7.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Pyr_redox PF00070.22 EOO03346.1 - 1.6e-14 54.0 0.0 2.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO03346.1 - 2.5e-08 33.2 0.0 0.0016 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO03346.1 - 9.2e-08 32.1 0.0 0.00087 19.2 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EOO03346.1 - 3.2e-07 30.6 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EOO03346.1 - 0.0007 18.3 0.0 0.13 10.8 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase K_oxygenase PF13434.1 EOO03346.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EOO03346.1 - 0.0018 17.2 0.0 0.014 14.3 0.0 1.9 1 1 1 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 EOO03346.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EOO03346.1 - 0.036 14.0 0.1 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EOO03346.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.9 EOO03346.1 - 0.12 10.8 0.1 2.1 6.7 0.1 2.1 1 1 1 2 2 2 0 HI0933-like protein DUF1996 PF09362.5 EOO03347.1 - 7.9e-59 199.1 1.0 1.1e-58 198.6 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_3 PF01494.14 EOO03348.1 - 4.6e-20 71.9 0.2 5e-19 68.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EOO03348.1 - 4.1e-07 29.9 2.8 0.008 15.9 0.1 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EOO03348.1 - 0.0001 21.0 1.5 0.016 13.8 0.4 2.2 1 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EOO03348.1 - 0.0005 20.0 1.1 0.00096 19.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO03348.1 - 0.0017 17.3 1.9 0.031 13.1 1.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO03348.1 - 0.0085 16.1 0.1 0.064 13.2 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO03348.1 - 0.0092 14.8 2.2 0.017 13.9 0.7 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EOO03348.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO03348.1 - 0.027 13.3 0.2 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EOO03348.1 - 0.097 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EOO03348.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mgm101p PF06420.7 EOO03349.1 - 2.1e-88 294.0 0.0 3e-88 293.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Dak1 PF02733.12 EOO03350.1 - 7.6e-111 369.7 3.4 1.1e-110 369.2 2.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EOO03350.1 - 6e-44 149.7 0.1 1e-43 148.9 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain Pyr_redox_3 PF13738.1 EOO03352.1 - 1.5e-08 34.9 0.0 1.4e-07 31.7 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO03352.1 - 0.011 14.0 0.1 0.72 7.9 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EOO03352.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EOO03352.1 - 0.018 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EOO03353.1 - 8.9e-34 116.7 0.0 1.1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO03353.1 - 6.6e-17 62.1 0.3 8e-17 61.8 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO03353.1 - 1.9e-05 24.2 0.0 9.2e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EOO03353.1 - 9.4e-05 22.3 0.7 0.0004 20.3 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO03353.1 - 0.00079 19.1 0.3 0.0022 17.6 0.1 1.7 1 1 1 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EOO03353.1 - 0.0048 15.6 0.0 0.017 13.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EOO03353.1 - 0.066 12.1 0.1 0.19 10.6 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein Peptidase_A4 PF01828.12 EOO03355.1 - 2.5e-86 288.0 12.0 3.1e-86 287.7 8.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family adh_short PF00106.20 EOO03356.1 - 1.8e-31 109.2 2.3 2.4e-31 108.9 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03356.1 - 1.4e-17 64.2 0.0 1.8e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03356.1 - 1.9e-15 56.9 1.7 3.4e-15 56.1 1.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO03356.1 - 0.00014 21.3 0.1 0.00025 20.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO03356.1 - 0.00084 19.3 1.0 0.0019 18.1 0.7 1.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EOO03356.1 - 0.0051 16.5 0.4 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_5 PF08323.6 EOO03356.1 - 0.0088 15.5 0.0 0.27 10.7 0.0 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain Gag_spuma PF03276.9 EOO03356.1 - 0.023 13.0 0.0 0.031 12.6 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein ADH_zinc_N PF00107.21 EOO03356.1 - 0.083 12.4 0.3 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EOO03356.1 - 0.14 11.7 0.7 0.25 10.9 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EOO03357.1 - 2.7e-10 40.4 0.0 4.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PHO4 PF01384.15 EOO03359.1 - 3.7e-98 328.1 16.9 4.4e-98 327.9 11.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family SynMuv_product PF06047.6 EOO03361.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ras-induced vulval development antagonist adh_short PF00106.20 EOO03362.1 - 2.6e-19 69.7 0.3 3.5e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03362.1 - 7.1e-10 38.8 0.0 9.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO03362.1 - 1.1e-05 24.4 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EOO03362.1 - 0.00019 21.1 0.1 0.00039 20.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EOO03362.1 - 0.0012 19.0 0.3 0.0033 17.5 0.2 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EOO03362.1 - 0.042 14.2 0.1 0.093 13.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EOO03362.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EOO03362.1 - 0.24 10.9 1.5 1.8 8.1 0.5 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF885 PF05960.6 EOO03363.1 - 9.4e-49 166.9 0.0 1.4e-48 166.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Nuc_sug_transp PF04142.10 EOO03364.1 - 1.6e-77 259.9 4.3 2.3e-77 259.4 3.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EOO03364.1 - 4.6e-11 42.5 16.6 6e-06 25.9 0.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EOO03364.1 - 6.2e-09 35.1 6.7 1.7e-06 27.2 1.5 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EOO03364.1 - 6.5e-07 29.4 20.7 2.3e-05 24.4 1.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EOO03364.1 - 6.3e-05 23.1 13.6 0.00023 21.3 0.2 2.3 2 0 0 2 2 2 1 Multidrug resistance efflux transporter FUSC_2 PF13515.1 EOO03364.1 - 0.015 15.2 2.2 0.015 15.2 1.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Cu-oxidase_2 PF07731.9 EOO03365.1 - 3.1e-33 114.1 0.8 4e-33 113.8 0.6 1.2 1 0 0 1 1 1 1 Multicopper oxidase RepA_C PF04796.7 EOO03366.1 - 0.059 12.9 2.4 0.086 12.4 1.5 1.4 1 1 0 1 1 1 0 Plasmid encoded RepA protein WbqC PF08889.6 EOO03366.1 - 0.062 12.7 0.8 0.083 12.3 0.5 1.3 1 1 0 1 1 1 0 WbqC-like protein family DUF960 PF06124.6 EOO03366.1 - 0.18 12.1 2.0 0.31 11.3 1.4 1.4 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) MbeD_MobD PF04899.7 EOO03366.1 - 1.6 8.7 5.3 7 6.6 3.7 1.9 1 1 0 1 1 1 0 MbeD/MobD like HET PF06985.6 EOO03368.1 - 2.9e-32 111.7 0.0 5.1e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2-Hacid_dh_C PF02826.14 EOO03369.1 - 4.2e-54 182.3 0.0 7.2e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EOO03369.1 - 8.1e-18 64.1 0.0 1e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EOO03369.1 - 2.1e-07 30.9 0.0 5.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EOO03369.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Prp19 PF08606.6 EOO03369.1 - 0.046 13.4 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like IlvN PF07991.7 EOO03369.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Pyr_redox_3 PF13738.1 EOO03370.1 - 3.2e-27 95.9 0.0 1.1e-26 94.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EOO03370.1 - 2.1e-15 55.9 0.0 8.2e-15 53.9 0.0 1.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EOO03370.1 - 1.8e-14 53.4 0.0 5.1e-13 48.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EOO03370.1 - 4.3e-12 46.3 0.0 9.1e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO03370.1 - 7.3e-11 42.0 0.2 1.7e-07 31.1 0.1 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EOO03370.1 - 7.4e-06 24.6 0.1 0.048 12.1 0.1 2.4 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EOO03370.1 - 9e-06 25.6 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO03370.1 - 4.5e-05 22.5 1.2 0.037 12.9 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EOO03370.1 - 4.9e-05 22.5 0.0 8.2e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO03370.1 - 0.00033 19.6 0.1 0.38 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EOO03370.1 - 0.00042 19.4 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EOO03370.1 - 0.00068 18.6 0.0 0.0034 16.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EOO03370.1 - 0.0018 17.4 0.2 0.051 12.6 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EOO03370.1 - 0.22 11.9 0.6 24 5.4 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pam16 PF03656.8 EOO03371.1 - 6.6e-33 113.2 0.3 8.1e-33 112.9 0.2 1.0 1 0 0 1 1 1 1 Pam16 Cu_amine_oxid PF01179.15 EOO03372.1 - 8.3e-171 568.2 0.0 1e-170 567.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EOO03372.1 - 2.7e-22 78.7 0.5 1.8e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EOO03372.1 - 3.7e-13 49.3 0.1 6.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain OPT PF03169.10 EOO03373.1 - 5e-80 269.7 24.5 2e-66 224.7 9.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Ank_2 PF12796.2 EOO03373.1 - 8.6e-15 54.8 0.0 2.1e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EOO03373.1 - 1e-13 50.2 0.1 1.5e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EOO03373.1 - 5.2e-13 47.8 0.1 3.5e-07 29.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EOO03373.1 - 3.3e-12 46.5 3.8 9.5e-08 32.3 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO03373.1 - 1.9e-10 40.6 0.3 0.00019 21.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Strep_67kDa_ant PF06100.6 EOO03375.1 - 3.3e-232 771.2 0.1 3.9e-232 771.0 0.1 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 EOO03375.1 - 6.9e-08 32.3 0.0 3.3e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO03375.1 - 0.00013 20.9 0.0 0.001 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO03375.1 - 0.004 17.2 0.2 0.24 11.4 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO03375.1 - 0.022 15.1 0.1 4 7.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EOO03375.1 - 0.027 14.2 0.1 0.87 9.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EOO03375.1 - 0.051 13.4 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EOO03375.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TPR_19 PF14559.1 EOO03376.1 - 1.4e-09 38.0 3.0 0.41 11.0 0.0 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EOO03376.1 - 3.7e-08 33.1 1.2 0.034 14.0 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EOO03376.1 - 3.5e-06 26.4 1.6 0.0036 17.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EOO03376.1 - 3.6e-06 26.3 0.0 0.0043 16.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EOO03376.1 - 0.0002 21.6 3.5 23 5.9 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EOO03376.1 - 0.0022 17.6 0.1 2.6 8.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EOO03376.1 - 0.0047 16.5 0.0 0.92 9.1 0.0 3.6 3 2 0 3 3 3 1 TPR repeat TPR_10 PF13374.1 EOO03376.1 - 0.0077 16.1 0.1 30 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EOO03376.1 - 0.0083 16.5 0.1 18 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EOO03376.1 - 0.011 15.5 0.2 14 5.6 0.0 3.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EOO03376.1 - 0.019 15.0 1.3 6.4 6.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EOO03376.1 - 0.13 11.8 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 EOO03377.1 - 1.7e-22 79.8 0.0 3.5e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EOO03377.1 - 1.1e-12 47.3 10.7 0.0064 16.3 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.9 EOO03377.1 - 9.2e-06 25.3 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EOO03377.1 - 0.0056 16.4 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PQQ_3 PF13570.1 EOO03377.1 - 0.25 11.6 3.7 2 8.8 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain MFS_1 PF07690.11 EOO03378.1 - 1e-34 119.8 47.8 2.1e-34 118.8 33.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03378.1 - 1.4e-10 40.4 11.0 1.4e-10 40.4 7.6 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Neisseria_TspB PF05616.8 EOO03378.1 - 0.23 9.7 3.7 0.32 9.2 2.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MFS_1 PF07690.11 EOO03379.1 - 9.3e-34 116.6 24.0 9.3e-34 116.6 16.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.18 EOO03380.1 - 3.4e-42 144.6 0.1 1.8e-40 139.0 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EOO03380.1 - 1.1e-06 28.1 0.1 3.9e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EOO03380.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EOO03380.1 - 0.085 11.2 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 EOO03380.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Lipase_GDSL_2 PF13472.1 EOO03381.1 - 1.1e-12 48.4 0.0 1.4e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO03381.1 - 1.1e-07 31.9 0.5 9.4e-07 28.8 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EOO03381.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FAM91_N PF14647.1 EOO03381.1 - 0.049 12.6 0.0 0.1 11.6 0.0 1.4 1 1 0 1 1 1 0 FAM91 N-terminus Glutaredoxin PF00462.19 EOO03382.1 - 5.3e-16 58.3 0.5 2.5e-15 56.2 0.0 2.3 3 0 0 3 3 3 1 Glutaredoxin GST_N_3 PF13417.1 EOO03382.1 - 0.0019 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EF-1_beta_acid PF10587.4 EOO03382.1 - 0.052 13.6 3.3 0.052 13.6 2.3 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region RNase_T PF00929.19 EOO03383.1 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Trehalose_recp PF06151.8 EOO03383.1 - 0.25 9.6 0.0 0.99 7.6 0.0 1.7 2 0 0 2 2 2 0 Trehalose receptor DUF3828 PF12883.2 EOO03384.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3828) Cys_Met_Meta_PP PF01053.15 EOO03385.1 - 3.2e-140 466.8 0.1 3.6e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EOO03385.1 - 1.7e-07 30.5 0.1 2.4e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EOO03385.1 - 2.7e-06 26.3 0.7 5.2e-06 25.4 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EOO03385.1 - 2.5e-05 23.4 1.2 4.4e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EOO03385.1 - 0.0059 15.3 0.2 0.01 14.5 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_S19 PF00203.16 EOO03386.1 - 7.8e-34 115.1 0.3 1.2e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EOO03386.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH ADH_N PF08240.7 EOO03388.1 - 3.2e-13 49.3 0.0 6.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03388.1 - 2.6e-07 30.2 0.2 5.1e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S-AdoMet_synt_C PF02773.11 EOO03389.1 - 6.1e-77 256.0 0.3 1.1e-76 255.2 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EOO03389.1 - 1.8e-47 160.1 0.0 3.2e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EOO03389.1 - 1.8e-42 143.5 1.0 3.3e-42 142.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 EOO03390.1 - 2e-72 243.5 0.0 2.5e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EOO03390.1 - 3.8e-06 27.7 0.0 1e-05 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EOO03390.1 - 0.0006 19.7 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EOO03390.1 - 0.0031 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EOO03390.1 - 0.0042 16.9 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EOO03390.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EOO03390.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EOO03390.1 - 0.011 15.6 0.0 0.041 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EOO03390.1 - 0.023 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EOO03390.1 - 0.023 14.1 0.0 0.062 12.7 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain Septin PF00735.13 EOO03390.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EOO03390.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EOO03390.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EOO03390.1 - 0.042 13.5 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EOO03390.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPV_E1_C PF00519.12 EOO03390.1 - 0.055 12.0 0.1 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.22 EOO03390.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 EOO03390.1 - 0.065 12.6 0.0 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Thymidylate_kin PF02223.12 EOO03390.1 - 0.079 12.3 0.0 8.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase KAP_NTPase PF07693.9 EOO03390.1 - 0.094 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.1 EOO03390.1 - 0.099 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EOO03390.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EOO03390.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase BNR_2 PF13088.1 EOO03391.1 - 0.035 13.3 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain TPR_1 PF00515.23 EOO03392.1 - 8.9e-25 85.2 3.6 4e-08 32.5 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EOO03392.1 - 1.3e-24 85.6 7.3 6.2e-10 38.5 0.3 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EOO03392.1 - 1.9e-22 77.2 7.1 7.6e-07 28.5 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EOO03392.1 - 4.7e-18 65.3 8.8 2.7e-07 31.0 0.0 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EOO03392.1 - 2.8e-16 58.2 5.0 0.00049 20.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EOO03392.1 - 3.9e-16 58.0 9.8 8.2e-06 26.0 0.1 5.6 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EOO03392.1 - 1.8e-13 50.5 5.2 0.0029 17.9 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EOO03392.1 - 2e-13 49.0 0.8 0.00014 21.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EOO03392.1 - 2.5e-13 48.7 3.2 0.0012 18.4 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EOO03392.1 - 2.6e-13 49.6 7.7 1e-07 31.7 0.1 4.1 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_20 PF14561.1 EOO03392.1 - 1.5e-09 37.8 3.8 0.0021 18.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EOO03392.1 - 3.7e-09 36.3 2.4 0.004 16.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EOO03392.1 - 1.9e-08 34.2 2.2 0.44 11.1 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EOO03392.1 - 0.00026 20.1 0.4 0.55 9.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 EOO03392.1 - 0.0023 17.9 1.3 0.0075 16.3 0.1 2.2 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_3 PF07720.7 EOO03392.1 - 0.0035 17.0 0.1 1.5 8.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EOO03392.1 - 0.061 13.2 9.0 0.71 9.8 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF1641 PF07849.6 EOO03392.1 - 0.12 12.0 0.2 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Amidase PF01425.16 EOO03393.1 - 2.8e-90 303.2 0.0 3.3e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Apq12 PF12716.2 EOO03394.1 - 9.6e-08 31.6 9.1 1.6e-07 30.8 6.3 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis NicO PF03824.11 EOO03394.1 - 0.0097 15.2 0.6 0.013 14.8 0.4 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DsbB PF02600.11 EOO03394.1 - 0.035 13.8 3.2 0.068 12.9 2.2 1.5 1 1 0 1 1 1 0 Disulfide bond formation protein DsbB BTP PF05232.7 EOO03394.1 - 0.19 11.5 4.6 0.43 10.3 3.2 1.6 1 1 0 1 1 1 0 Bacterial Transmembrane Pair family p450 PF00067.17 EOO03395.1 - 1.8e-50 171.8 0.0 2.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.17 EOO03396.1 - 8.1e-54 182.7 5.4 1e-53 182.4 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Brix PF04427.13 EOO03398.1 - 3.9e-36 124.5 0.0 5.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyco_hydro_53 PF07745.8 EOO03399.1 - 4.1e-112 374.2 0.1 4.6e-112 374.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cupin_2 PF07883.6 EOO03400.1 - 0.039 13.4 0.1 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.17 EOO03400.1 - 0.11 12.7 0.4 0.25 11.5 0.1 1.7 1 1 0 2 2 2 0 JmjC domain, hydroxylase RRM_1 PF00076.17 EOO03401.1 - 2.8e-36 122.9 0.0 5.9e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03401.1 - 1.9e-27 94.9 0.0 1.2e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03401.1 - 2.1e-12 46.6 0.0 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EOO03401.1 - 0.004 16.8 0.1 0.071 12.8 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 Spo7_2_N PF15407.1 EOO03401.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 MFS_1 PF07690.11 EOO03402.1 - 3.3e-31 108.2 44.3 3.3e-31 108.2 30.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AIG1 PF04548.11 EOO03404.1 - 1.8e-08 33.7 0.1 3.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EOO03404.1 - 3.6e-08 33.3 0.6 3.3e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EOO03404.1 - 4e-05 22.8 0.1 8.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EOO03404.1 - 8.5e-05 23.0 0.1 0.00021 21.7 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 EOO03404.1 - 8.9e-05 22.8 6.2 0.18 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain Septin PF00735.13 EOO03404.1 - 0.00066 18.7 0.7 0.0015 17.6 0.0 1.9 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EOO03404.1 - 0.00091 19.0 11.4 0.098 12.4 0.1 3.5 2 2 1 3 3 3 2 Dynamin family SRPRB PF09439.5 EOO03404.1 - 0.0025 17.0 3.1 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EOO03404.1 - 0.0054 17.0 3.6 0.015 15.5 0.0 2.6 2 1 1 3 3 3 1 ABC transporter FeoB_N PF02421.13 EOO03404.1 - 0.0081 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF2229 PF09989.4 EOO03404.1 - 0.0097 15.3 2.9 0.016 14.6 2.0 1.2 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) Tropomyosin_1 PF12718.2 EOO03404.1 - 0.011 15.6 10.6 0.017 14.9 7.3 1.3 1 0 0 1 1 1 0 Tropomyosin like cobW PF02492.14 EOO03404.1 - 0.029 13.8 0.2 0.063 12.7 0.1 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 EOO03404.1 - 0.032 13.3 0.3 0.068 12.3 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 EOO03404.1 - 0.043 13.4 0.2 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EOO03404.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EOO03404.1 - 0.058 13.0 3.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EOO03404.1 - 0.058 12.8 0.8 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EOO03404.1 - 0.064 14.0 0.6 0.13 13.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EOO03404.1 - 0.093 12.9 0.4 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AvrB_AvrC PF05394.6 EOO03404.1 - 0.097 11.6 0.4 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Avirulence protein AAA_10 PF12846.2 EOO03404.1 - 0.1 12.0 0.5 0.59 9.5 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain Lipoprotein_6 PF01441.14 EOO03404.1 - 0.12 12.2 5.5 0.18 11.6 3.8 1.2 1 0 0 1 1 1 0 Lipoprotein Snf7 PF03357.16 EOO03404.1 - 0.12 11.7 8.2 0.21 10.9 5.7 1.3 1 0 0 1 1 1 0 Snf7 MobB PF03205.9 EOO03404.1 - 0.17 11.5 5.6 0.039 13.6 0.9 2.2 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF607 PF04678.8 EOO03404.1 - 0.31 10.9 5.4 2.2 8.1 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF607 AAA_18 PF13238.1 EOO03404.1 - 0.32 11.3 3.0 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain LCD1 PF09798.4 EOO03404.1 - 0.46 8.4 6.2 0.66 7.8 4.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein OmpH PF03938.9 EOO03404.1 - 0.87 9.5 6.9 1.4 8.8 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.12 EOO03404.1 - 4 7.1 12.3 0.28 10.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 DivIC PF04977.10 EOO03404.1 - 6 6.4 7.3 1.7 8.2 1.5 2.2 1 1 1 2 2 2 0 Septum formation initiator zf-RanBP PF00641.13 EOO03404.1 - 6.1 6.0 6.9 1.5 8.0 1.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Sugar_tr PF00083.19 EOO03405.1 - 6.4e-58 196.4 13.2 1e-43 149.5 6.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EOO03405.1 - 3.4e-21 75.3 25.2 1.6e-18 66.5 12.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO03405.1 - 0.005 15.0 3.3 0.0071 14.5 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EOO03405.1 - 0.0069 16.1 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 MFS_1 like family Acyl-CoA_dh_C PF12806.2 EOO03405.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF791 PF05631.9 EOO03405.1 - 0.23 10.1 6.6 0.026 13.2 1.5 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF791) Cu_amine_oxid PF01179.15 EOO03406.1 - 1.4e-161 537.8 0.0 1.7e-161 537.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EOO03406.1 - 7.7e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EOO03406.1 - 0.0027 17.7 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_67M PF07488.7 EOO03408.1 - 1.6e-151 503.8 0.0 2.5e-151 503.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EOO03408.1 - 2.7e-91 305.0 0.9 3.9e-91 304.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EOO03408.1 - 1.4e-28 99.3 0.1 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EOO03408.1 - 0.0018 18.8 0.1 0.0037 17.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Dabb PF07876.7 EOO03409.1 - 8e-24 83.9 0.0 9.3e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Seryl_tRNA_N PF02403.17 EOO03410.1 - 0.034 14.1 4.3 0.053 13.5 3.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 EOO03410.1 - 1.3 8.8 5.2 1.8 8.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) adh_short PF00106.20 EOO03411.1 - 1.4e-13 51.1 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03411.1 - 6.9e-06 25.8 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO03411.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3431 PF11913.3 EOO03412.1 - 2.2e-56 190.8 0.1 2.6e-56 190.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Epimerase PF01370.16 EOO03413.1 - 5.1e-25 88.2 0.0 6.5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EOO03413.1 - 1.2e-11 44.0 0.6 1.6e-07 30.5 0.0 3.0 2 1 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EOO03413.1 - 3.8e-11 42.4 0.0 4.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EOO03413.1 - 4.9e-11 42.0 0.1 3.6e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EOO03413.1 - 6.1e-07 28.4 0.0 5.6e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EOO03413.1 - 0.00024 21.0 0.8 0.053 13.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EOO03413.1 - 0.0015 18.2 0.7 0.096 12.3 0.0 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EOO03413.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding MARVEL PF01284.18 EOO03414.1 - 2.3e-15 56.6 12.6 2.7e-15 56.4 8.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain TrbE PF11100.3 EOO03414.1 - 6.2 6.7 7.2 4.8 7.1 2.5 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TrbE YjgP_YjgQ PF03739.9 EOO03414.1 - 7 5.2 8.7 13 4.4 6.1 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family MARVEL PF01284.18 EOO03416.1 - 5.4e-05 23.0 19.7 7.3e-05 22.6 13.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.1 EOO03416.1 - 0.089 12.7 10.9 0.034 14.0 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.6 EOO03416.1 - 7.5 6.1 23.5 18 4.9 10.7 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Flavoprotein PF02441.14 EOO03417.1 - 9.8e-17 60.8 0.0 1.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EOO03417.1 - 0.072 13.6 0.0 8.3 7.0 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) ABC_tran PF00005.22 EOO03418.1 - 2.8e-36 124.8 3.3 9.2e-23 81.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EOO03418.1 - 7.7e-20 70.5 9.8 7.7e-20 70.5 6.8 4.8 4 1 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EOO03418.1 - 3.1e-13 50.3 1.0 7.3e-05 22.8 0.0 3.9 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EOO03418.1 - 1.9e-09 37.0 2.2 0.0012 18.1 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EOO03418.1 - 0.00087 19.1 0.6 0.93 9.4 0.2 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EOO03418.1 - 0.0017 19.1 0.1 0.01 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EOO03418.1 - 0.0071 15.8 1.7 2 7.7 0.2 3.0 2 1 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EOO03418.1 - 0.03 14.4 0.0 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EOO03418.1 - 0.034 14.4 0.0 0.034 14.4 0.0 3.7 3 1 0 3 3 2 0 AAA domain MobB PF03205.9 EOO03418.1 - 0.035 13.8 0.2 0.11 12.2 0.2 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EOO03418.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EOO03418.1 - 0.054 13.8 1.0 0.28 11.4 0.0 2.7 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.1 EOO03418.1 - 0.097 12.4 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain rve_3 PF13683.1 EOO03418.1 - 0.28 10.7 1.2 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain AAA_15 PF13175.1 EOO03418.1 - 0.62 9.0 13.1 0.66 8.9 0.1 4.3 3 1 2 5 5 5 0 AAA ATPase domain Tubulin PF00091.20 EOO03419.1 - 1.9e-70 237.0 0.0 3.3e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EOO03419.1 - 4.1e-49 165.8 0.1 6.5e-49 165.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EOO03419.1 - 8.3e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EOO03419.1 - 0.0045 16.4 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.16 EOO03420.1 - 4.8e-13 48.8 3.9 7.6e-13 48.2 2.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EOO03420.1 - 3.1e-06 26.9 6.2 3.1e-06 26.9 4.3 1.5 2 0 0 2 2 2 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 EOO03420.1 - 0.0092 14.9 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.12 EOO03420.1 - 0.15 12.3 2.7 0.34 11.2 1.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Ndc1_Nup PF09531.5 EOO03420.1 - 5.9 5.1 5.4 9.4 4.5 3.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP40_C PF05022.7 EOO03421.1 - 9.1e-26 90.1 0.5 3e-25 88.5 0.3 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Methyltransf_25 PF13649.1 EOO03422.1 - 2.7e-07 30.8 0.0 5.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03422.1 - 5e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03422.1 - 0.016 15.7 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FF PF01846.14 EOO03422.1 - 0.11 12.4 2.9 0.97 9.4 0.0 3.1 3 0 0 3 3 3 0 FF domain MARVEL PF01284.18 EOO03423.1 - 0.078 12.7 4.9 3.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Membrane-associating domain Peptidase_A24 PF01478.13 EOO03423.1 - 0.15 12.2 6.3 1.8 8.7 1.0 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family NnrU PF07298.6 EOO03423.1 - 0.58 9.4 8.1 1.2 8.4 1.4 2.1 2 0 0 2 2 2 0 NnrU protein Tic20 PF09685.5 EOO03423.1 - 4.3 7.3 11.5 2.2 8.3 3.8 2.2 2 0 0 2 2 2 0 Tic20-like protein Complex1_51K PF01512.12 EOO03424.1 - 5.5e-48 162.5 0.0 1e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EOO03424.1 - 5.6e-18 63.8 1.1 5.6e-18 63.8 0.8 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PEX11 PF05648.9 EOO03424.1 - 3.3e-17 62.5 0.0 1.5e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SLBB PF10531.4 EOO03424.1 - 2.8e-08 33.5 0.0 6.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain adh_short PF00106.20 EOO03427.1 - 2.7e-11 43.6 0.0 7.4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO03427.1 - 3.6e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EOO03427.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWA_CoxE PF05762.9 EOO03428.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DIOX_N PF14226.1 EOO03429.1 - 5.1e-26 91.4 0.0 9.6e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EOO03429.1 - 6.3e-12 45.6 0.0 3.2e-11 43.3 0.0 2.1 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EOO03430.1 - 2.2e-16 60.2 0.1 3.2e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03430.1 - 3.7e-09 36.4 0.2 5.4e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO03430.1 - 0.00013 21.5 0.1 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EOO03430.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EOO03430.1 - 0.0068 15.3 0.5 0.011 14.7 0.4 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EOO03430.1 - 0.0099 14.9 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain vATP-synt_AC39 PF01992.11 EOO03431.1 - 1.9e-119 398.7 0.0 2.1e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EOO03432.1 - 6.3e-53 178.0 0.7 1.1e-52 177.2 0.5 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EOO03432.1 - 1.2e-26 92.2 0.0 2.2e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EOO03432.1 - 8.7e-15 54.6 0.3 8.7e-15 54.6 0.2 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ubiquitin PF00240.18 EOO03433.1 - 0.00047 19.5 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1923 PF09083.5 EOO03433.1 - 0.32 10.5 1.2 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Menin PF05053.8 EOO03433.1 - 1 7.4 2.8 1.3 7.0 1.9 1.1 1 0 0 1 1 1 0 Menin DUF1517 PF07466.6 EOO03433.1 - 2.6 6.9 3.9 0.46 9.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Transp_cyt_pur PF02133.10 EOO03434.1 - 1.7e-95 320.1 40.7 1.9e-95 320.0 28.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_S2 PF00318.15 EOO03435.1 - 1.8e-42 144.9 0.1 3.2e-22 78.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EOO03436.1 - 1.7e-15 56.5 0.1 4.2e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 RasGAP PF00616.14 EOO03438.1 - 6.6e-19 68.3 0.0 6e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EOO03438.1 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Asn_synthase PF00733.16 EOO03439.1 - 1.7e-68 230.8 0.0 2.3e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EOO03439.1 - 3.4e-33 114.0 0.0 9e-33 112.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EOO03439.1 - 1.8e-19 70.0 0.1 7.9e-19 67.9 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EOO03439.1 - 9.2e-07 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EOO03439.1 - 0.00057 18.8 0.1 0.0022 16.9 0.0 1.9 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EOO03439.1 - 0.085 11.5 0.0 0.19 10.3 0.0 1.4 1 1 0 1 1 1 0 Glutamine amidotransferases class-II Porin_3 PF01459.17 EOO03440.1 - 8.4e-63 212.2 7.4 1.8e-62 211.1 5.1 1.5 1 1 0 1 1 1 1 Eukaryotic porin SPAN PF02510.9 EOO03441.1 - 0.095 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein FoP_duplication PF13865.1 EOO03441.1 - 4.7 7.7 5.7 7.3 7.1 4.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 COQ7 PF03232.8 EOO03443.1 - 1.5e-64 216.5 0.0 1.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EOO03443.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.6 1 1 0 1 1 1 0 Rubrerythrin DUF202 PF02656.10 EOO03444.1 - 1.4e-13 50.7 4.9 4.1e-13 49.3 2.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.6 EOO03444.1 - 0.52 9.9 7.3 1.5 8.4 5.1 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2189 PF09955.4 EOO03444.1 - 0.79 9.6 5.7 0.19 11.6 0.8 1.8 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF4131 PF13567.1 EOO03444.1 - 2.8 7.3 5.9 1.9 7.8 2.3 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) FTHFS PF01268.14 EOO03445.1 - 5.2e-258 856.5 0.1 6.9e-258 856.1 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EOO03445.1 - 8.3e-68 226.5 3.0 1.1e-67 226.1 0.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EOO03445.1 - 1.3e-38 131.5 0.1 2.5e-38 130.6 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 EOO03445.1 - 0.13 11.6 0.2 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ino80_Iec3 PF14612.1 EOO03446.1 - 2.1e-49 168.6 4.0 4.6e-26 92.2 3.3 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Pex19 PF04614.7 EOO03447.1 - 4e-65 219.8 12.4 7.7e-65 218.9 8.6 1.3 1 0 0 1 1 1 1 Pex19 protein family FliE PF02049.13 EOO03447.1 - 0.43 10.6 9.7 0.58 10.2 3.2 2.9 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Gluconate_2-dh3 PF13618.1 EOO03447.1 - 1.2 9.3 8.2 2.7 8.1 4.2 2.4 1 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Gln-synt_C PF00120.19 EOO03448.1 - 4.2e-55 186.6 0.0 6.6e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EOO03448.1 - 1.8e-28 99.8 0.0 3.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase NmrA PF05368.8 EOO03450.1 - 9.9e-30 103.5 0.2 2.6e-29 102.1 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO03450.1 - 8.7e-10 38.8 0.4 1.3e-09 38.3 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO03450.1 - 1.7e-05 24.3 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EOO03450.1 - 0.00028 20.8 0.2 0.00061 19.7 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EOO03450.1 - 0.071 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EOO03450.1 - 0.076 12.0 0.3 0.15 11.0 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 EOO03450.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EOO03450.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain RTA1 PF04479.8 EOO03451.1 - 1.3e-17 64.0 8.2 1.7e-17 63.7 5.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Peptidase_M19 PF01244.16 EOO03452.1 - 6.9e-106 353.7 0.0 9.1e-106 353.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) CFEM PF05730.6 EOO03453.1 - 0.83 9.5 13.5 1.6 8.6 8.9 2.0 1 1 0 1 1 1 0 CFEM domain p450 PF00067.17 EOO03454.1 - 2.7e-42 144.8 0.0 3.3e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C2 PF00648.16 EOO03455.1 - 6.2e-56 189.5 1.3 3.3e-38 131.3 0.4 2.6 2 0 0 2 2 2 2 Calpain family cysteine protease Ribosomal_S18 PF01084.15 EOO03456.1 - 4.3e-12 45.6 0.0 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_L24e PF01246.15 EOO03459.1 - 6e-29 99.7 3.2 1.3e-28 98.6 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e PGA2 PF07543.7 EOO03459.1 - 0.12 12.1 10.9 0.26 11.0 7.3 1.7 1 1 0 1 1 1 0 Protein trafficking PGA2 KIAA1430 PF13879.1 EOO03459.1 - 0.52 10.7 6.1 0.12 12.8 1.9 1.6 2 1 0 2 2 2 0 KIAA1430 homologue SPT16 PF08644.6 EOO03461.1 - 6e-57 191.7 0.1 6e-57 191.7 0.1 3.2 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EOO03461.1 - 8.9e-54 181.4 0.6 2.7e-53 179.8 0.4 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EOO03461.1 - 1.4e-24 86.8 0.0 2.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EOO03461.1 - 2.4e-22 78.7 0.1 6.7e-22 77.2 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Alba PF01918.16 EOO03462.1 - 1.7e-05 24.3 0.1 6.3e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Alba Ureidogly_hydro PF04115.7 EOO03463.1 - 2.4e-26 92.0 0.0 3.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF3697 PF12478.3 EOO03463.1 - 0.0072 15.9 0.2 0.0072 15.9 0.2 2.3 3 0 0 3 3 3 1 Ubiquitin-associated protein 2 ALAD PF00490.16 EOO03464.1 - 3.3e-117 391.0 0.0 3.7e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Abhydrolase_3 PF07859.8 EOO03465.1 - 1.8e-58 197.6 0.0 2.3e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EOO03465.1 - 1.9e-06 26.8 0.1 1.2e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EOO03465.1 - 0.00014 21.1 0.0 0.52 9.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EOO03465.1 - 0.00036 20.4 0.4 0.00068 19.5 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO03465.1 - 0.00043 20.0 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EOO03465.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family GSH_synth_ATP PF03917.12 EOO03465.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Glyco_hydro_76 PF03663.9 EOO03466.1 - 1.6e-151 504.9 10.4 2.1e-151 504.5 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EOO03466.1 - 0.033 13.2 8.0 0.67 8.9 0.0 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Tbf5 PF06331.7 EOO03467.1 - 1.3e-28 98.5 0.5 1.4e-28 98.4 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Siah-Interact_N PF09032.6 EOO03469.1 - 0.0011 18.9 1.1 0.0011 18.9 0.7 2.0 2 0 0 2 2 2 1 Siah interacting protein, N terminal bZIP_1 PF00170.16 EOO03469.1 - 0.0016 18.3 18.6 0.05 13.5 12.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor Mnd1 PF03962.10 EOO03469.1 - 0.027 14.1 7.7 0.038 13.6 5.3 1.2 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 EOO03469.1 - 0.056 13.7 0.6 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rep_4 PF05797.6 EOO03469.1 - 0.093 11.4 0.7 0.12 11.0 0.5 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) ATG16 PF08614.6 EOO03469.1 - 0.095 12.5 11.6 0.14 11.9 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EOO03469.1 - 0.11 12.7 6.0 0.19 12.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CENP-K PF11802.3 EOO03469.1 - 0.11 11.6 2.0 0.16 11.2 1.4 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF2937 PF11157.3 EOO03469.1 - 0.24 10.7 1.1 0.42 9.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Birna_RdRp PF04197.7 EOO03469.1 - 0.28 9.1 3.3 0.32 8.9 2.3 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) IncA PF04156.9 EOO03469.1 - 0.54 9.8 5.5 0.77 9.3 3.8 1.2 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 EOO03469.1 - 2.8 6.1 11.6 3.8 5.6 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein MerR_2 PF13591.1 EOO03469.1 - 3 7.4 5.6 13 5.4 3.9 1.9 1 1 0 1 1 1 0 MerR HTH family regulatory protein DUF4407 PF14362.1 EOO03469.1 - 3 6.7 6.3 3.9 6.3 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1880 PF08976.6 EOO03469.1 - 7.8 6.6 7.1 0.61 10.2 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) bZIP_2 PF07716.10 EOO03469.1 - 8.2 6.3 18.7 6.7 6.6 2.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Med31 PF05669.7 EOO03470.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SOH1 FTA4 PF13093.1 EOO03471.1 - 7.5e-63 211.8 0.0 9e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tautomerase_3 PF14832.1 EOO03471.1 - 0.083 12.8 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative oxalocrotonate tautomerase enzyme Cep57_MT_bd PF06657.8 EOO03471.1 - 0.15 12.0 2.3 0.18 11.7 0.5 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2462 PF09495.5 EOO03474.1 - 7e-15 55.5 16.0 7e-15 55.5 11.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.11 EOO03474.1 - 0.0011 18.4 3.9 0.0012 18.2 2.7 1.0 1 0 0 1 1 1 1 Potyvirus P1 protease DnaJ PF00226.26 EOO03475.1 - 8.4e-22 76.6 1.9 1.3e-21 76.0 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4175 PF13779.1 EOO03475.1 - 1.4 6.4 4.4 2.2 5.8 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cu-oxidase_3 PF07732.10 EOO03476.1 - 3.9e-45 152.3 5.7 5.2e-43 145.5 1.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EOO03476.1 - 1.4e-42 144.4 10.9 7.9e-39 132.3 0.2 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EOO03476.1 - 7.6e-33 113.6 0.1 2.4e-32 112.0 0.1 1.9 1 0 0 1 1 1 1 Multicopper oxidase SH3_9 PF14604.1 EOO03477.1 - 3.2e-13 49.0 0.0 7e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EOO03477.1 - 3.2e-12 46.1 0.0 6.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EOO03477.1 - 2.2e-11 42.9 0.0 4.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EOO03477.1 - 1.6e-08 34.6 0.0 3.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EOO03477.1 - 3.1e-06 27.4 0.0 7.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EOO03477.1 - 0.00022 20.6 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pox_I6 PF04595.8 EOO03477.1 - 0.061 12.0 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family PH_8 PF15409.1 EOO03477.1 - 0.12 12.4 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.13 EOO03478.1 - 4e-33 113.6 0.0 9.5e-33 112.4 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain UPF0160 PF03690.8 EOO03479.1 - 3.6e-124 414.3 0.0 4.1e-124 414.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) JAB PF01398.16 EOO03480.1 - 2.6e-17 62.6 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EOO03480.1 - 9e-14 51.5 0.2 1.5e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Y_phosphatase3 PF13350.1 EOO03481.1 - 3.4e-27 95.6 0.0 7.4e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EOO03481.1 - 1.7e-11 44.0 0.0 6e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Methyltransf_23 PF13489.1 EOO03482.1 - 2.3e-15 56.6 0.1 4.5e-15 55.7 0.1 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03482.1 - 2.3e-09 37.8 0.0 3.7e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03482.1 - 4.9e-07 29.4 0.0 4.7e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03482.1 - 1.4e-06 28.6 0.0 4.2e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03482.1 - 1.5e-06 28.6 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03482.1 - 2.1e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO03482.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EOO03482.1 - 0.0052 15.9 0.0 0.018 14.1 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EOO03482.1 - 0.0068 15.9 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EOO03482.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF1793 PF08760.6 EOO03483.1 - 5.7e-62 208.5 0.1 1.6e-61 207.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Endosulfine PF04667.12 EOO03484.1 - 9.4e-22 76.7 0.0 1.8e-21 75.9 0.0 1.5 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region SNF2_N PF00176.18 EOO03485.1 - 3.1e-80 269.1 0.1 3.1e-80 269.1 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EOO03485.1 - 1.8e-44 150.2 2.9 5.1e-44 148.7 2.0 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EOO03485.1 - 6.1e-35 120.0 7.3 6.1e-35 120.0 5.0 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EOO03485.1 - 2.8e-15 55.9 0.0 9.5e-15 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO03485.1 - 7.3e-08 32.4 0.8 4.3e-07 29.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EOO03485.1 - 0.00022 20.7 0.0 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EOO03485.1 - 0.00094 19.1 0.1 0.46 10.5 0.0 3.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 EOO03485.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EOO03485.1 - 0.045 13.6 0.0 0.2 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EOO03486.1 - 0.0026 17.9 16.3 0.037 14.3 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EOO03486.1 - 0.017 15.3 0.3 0.017 15.3 0.2 4.3 4 1 0 4 4 4 0 Zinc finger, C2H2 type Nitroreductase PF00881.19 EOO03486.1 - 0.036 13.8 0.0 0.14 11.9 0.0 1.9 1 1 1 2 2 2 0 Nitroreductase family Salp15 PF12115.3 EOO03486.1 - 1.5 9.0 5.8 1.8 8.8 3.3 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Methyltransf_11 PF08241.7 EOO03488.1 - 1.2e-13 51.3 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO03488.1 - 1.6e-13 50.7 0.0 2.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03488.1 - 2.5e-10 40.7 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03488.1 - 2.9e-09 36.6 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03488.1 - 7.4e-08 32.9 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03488.1 - 2.8e-07 30.8 0.0 4.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO03488.1 - 7.1e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EOO03488.1 - 0.0015 17.2 0.0 0.002 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.13 EOO03488.1 - 0.037 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EOO03488.1 - 0.042 12.9 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EOO03488.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 2 0 0 2 2 2 0 Putative methyltransferase DOT1 PF08123.8 EOO03488.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Glyco_hydro_43 PF04616.9 EOO03489.1 - 9.6e-19 67.5 4.3 9.6e-19 67.5 3.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Tubulin PF00091.20 EOO03490.1 - 3.2e-73 246.1 0.0 4.5e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EOO03490.1 - 4.1e-46 156.1 0.3 8.9e-46 155.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EOO03490.1 - 1.6e-07 31.3 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EOO03490.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain Tctex-1 PF03645.8 EOO03491.1 - 4.1e-33 113.2 0.0 4.7e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NAD_binding_6 PF08030.7 EOO03492.1 - 2.7e-19 69.6 0.0 5.5e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EOO03492.1 - 8.6e-14 51.7 9.9 8.6e-14 51.7 6.8 2.8 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EOO03492.1 - 7.6e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EOO03492.1 - 0.00031 21.2 0.0 0.039 14.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1212 PF06738.7 EOO03492.1 - 1.7 8.0 12.3 7.2 6.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Patatin PF01734.17 EOO03493.1 - 5e-18 65.7 0.1 9.4e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase tRNA-synt_2b PF00587.20 EOO03494.1 - 1.1e-31 109.6 0.4 2e-31 108.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EOO03494.1 - 3.1e-18 65.7 8.2 6.4e-18 64.7 5.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Not3 PF04065.10 EOO03495.1 - 1.1e-99 332.4 20.7 1.7e-99 331.8 14.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EOO03495.1 - 2.6e-43 147.1 11.0 2.6e-43 147.1 7.6 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.6 EOO03495.1 - 0.0018 18.0 3.4 0.0022 17.7 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Syntaxin PF00804.20 EOO03495.1 - 0.0069 16.5 13.0 0.019 15.1 3.1 2.8 3 0 0 3 3 3 2 Syntaxin DUF2373 PF10180.4 EOO03495.1 - 0.0076 15.7 3.2 0.015 14.8 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EOO03495.1 - 0.011 15.6 9.9 0.067 13.1 0.4 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Poty_PP PF08440.5 EOO03495.1 - 0.49 9.4 3.9 0.15 11.1 0.6 1.6 2 0 0 2 2 2 0 Potyviridae polyprotein Sec5 PF15469.1 EOO03495.1 - 0.59 9.8 8.3 2 8.1 0.5 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Snapin_Pallidin PF14712.1 EOO03495.1 - 0.84 9.9 9.5 1.2 9.5 0.3 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.1 EOO03495.1 - 2.2 8.3 7.5 0.26 11.3 1.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF241 PF03087.9 EOO03495.1 - 2.3 7.6 12.2 0.75 9.2 6.1 1.8 1 1 1 2 2 2 0 Arabidopsis protein of unknown function CTP_transf_2 PF01467.21 EOO03496.1 - 1.2e-15 57.9 0.0 6.8e-13 48.9 0.0 3.1 2 1 0 2 2 2 2 Cytidylyltransferase MFS_1 PF07690.11 EOO03497.1 - 8.1e-12 44.5 15.6 2.6e-11 42.8 11.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SUZ PF12752.2 EOO03498.1 - 2.1e-15 56.9 1.3 2.1e-15 56.9 0.9 2.5 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EOO03498.1 - 1.2e-08 34.5 0.1 2.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain ABC1 PF03109.11 EOO03499.1 - 7.4e-32 109.8 0.0 1.2e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family PRELI PF04707.9 EOO03500.1 - 2.1e-42 144.3 0.0 2.6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF4435 PF14491.1 EOO03500.1 - 0.097 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) MCM PF00493.18 EOO03501.1 - 2.1e-140 467.2 0.0 3.5e-140 466.4 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EOO03501.1 - 8.3e-33 113.5 35.9 8.3e-33 113.5 24.9 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EOO03501.1 - 1.8e-21 76.8 0.1 4.5e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EOO03501.1 - 7.7e-08 31.7 0.0 4.3e-06 26.0 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EOO03501.1 - 2.4e-06 27.3 0.0 5.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EOO03501.1 - 0.0015 18.1 0.1 0.018 14.6 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EOO03501.1 - 0.0018 17.7 0.2 0.012 15.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 EOO03501.1 - 0.2 12.0 1.0 0.68 10.3 0.7 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain CENP-Q PF13094.1 EOO03502.1 - 0.0015 18.5 4.1 0.0087 16.0 2.8 2.3 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Phage_lysis PF03245.8 EOO03502.1 - 0.0077 16.2 6.5 1.3 9.0 2.0 2.7 2 0 0 2 2 2 2 Bacteriophage Rz lysis protein FlgN PF05130.7 EOO03502.1 - 0.011 15.9 1.1 0.011 15.9 0.7 2.5 1 1 1 2 2 2 0 FlgN protein End3 PF12761.2 EOO03502.1 - 0.02 14.5 3.6 0.026 14.1 1.9 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 SPATA24 PF15175.1 EOO03502.1 - 0.051 13.2 0.2 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 PV-1 PF06637.6 EOO03502.1 - 0.076 11.5 5.5 0.11 11.0 3.8 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1319 PF07028.6 EOO03502.1 - 0.1 12.7 1.3 7 6.8 0.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Kinetocho_Slk19 PF12709.2 EOO03502.1 - 0.15 12.1 4.5 0.18 11.8 1.2 2.6 1 1 1 2 2 2 0 Central kinetochore-associated SlyX PF04102.7 EOO03502.1 - 0.23 11.8 3.6 3.3 8.1 0.0 3.3 1 1 1 3 3 3 0 SlyX Retrotrans_gag PF03732.12 EOO03502.1 - 0.29 11.2 4.7 0.81 9.7 2.7 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein APG6 PF04111.7 EOO03502.1 - 0.39 9.7 5.0 0.63 9.0 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CorA PF01544.13 EOO03502.1 - 0.55 9.2 5.8 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FMN_bind_2 PF04299.7 EOO03503.1 - 1.1e-51 174.6 0.0 1.3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF605 PF04652.11 EOO03504.1 - 1.3 8.3 37.3 0.27 10.5 6.6 2.2 2 0 0 2 2 2 0 Vta1 like Iso_dh PF00180.15 EOO03505.1 - 3.7e-73 246.4 0.0 4.2e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EOO03505.1 - 0.097 12.6 0.2 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) ADH_N PF08240.7 EOO03506.1 - 3.9e-23 81.2 4.5 5.2e-23 80.8 3.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO03506.1 - 0.056 14.3 0.0 0.074 13.9 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_M24 PF00557.19 EOO03507.1 - 6.4e-44 150.0 0.1 8.2e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.7 EOO03507.1 - 0.44 10.3 5.2 0.97 9.2 3.6 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 NST1 PF13945.1 EOO03507.1 - 0.53 10.3 6.7 0.9 9.5 4.6 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3827 PF12877.2 EOO03507.1 - 0.72 7.8 5.5 1 7.4 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RR_TM4-6 PF06459.7 EOO03507.1 - 1.3 8.8 6.2 2.3 8.0 4.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cupin_5 PF06172.6 EOO03508.1 - 4.5e-20 71.9 0.0 2.6e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily (DUF985) zf-RING_5 PF14634.1 EOO03509.1 - 0.00085 19.0 6.9 0.00085 19.0 4.8 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Daxx PF03344.10 EOO03509.1 - 0.019 13.4 14.4 0.042 12.3 10.0 1.6 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EOO03509.1 - 0.45 8.4 11.1 8.1 4.3 7.2 2.2 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.7 EOO03509.1 - 1.1 8.5 15.5 2.1 7.5 10.7 1.4 1 0 0 1 1 1 0 SDA1 zf-C3HC4_2 PF13923.1 EOO03509.1 - 2.3 8.3 15.9 0.05 13.6 4.3 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COPIIcoated_ERV PF07970.7 EOO03511.1 - 1.7e-35 122.6 0.0 2.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EOO03511.1 - 1.2e-22 79.6 0.0 2.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.27 EOO03512.1 - 1e-30 104.4 1.4 1.2e-11 43.9 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EOO03512.1 - 0.0003 19.7 0.2 0.051 12.3 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Nucleoporin_N PF08801.6 EOO03512.1 - 0.00066 18.5 0.0 0.0015 17.4 0.0 1.6 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 EOO03512.1 - 0.0026 17.4 0.2 1.1 8.9 0.0 3.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EOO03512.1 - 0.0039 15.3 0.0 0.0051 15.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Glyco_hydro_31 PF01055.21 EOO03513.1 - 9.5e-168 558.5 2.3 1.2e-167 558.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EOO03513.1 - 1.2e-11 44.2 1.3 2.5e-10 40.0 0.8 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like SNF2_N PF00176.18 EOO03514.1 - 2.6e-11 42.8 0.0 4.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 EOO03514.1 - 3.9e-10 39.3 0.0 2.6e-07 30.0 0.0 2.9 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase PPR_2 PF13041.1 EOO03515.1 - 4.3e-13 48.9 0.0 1.3e-06 28.2 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.2 EOO03515.1 - 3e-10 39.3 0.0 0.0001 21.7 0.0 3.7 3 0 0 3 3 3 2 PPR repeat PPR PF01535.15 EOO03515.1 - 1.4e-07 31.0 0.3 0.0058 16.5 0.0 3.7 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EOO03515.1 - 2.9e-06 27.1 0.7 0.12 12.7 0.0 4.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain KIP1 PF07765.7 EOO03515.1 - 0.047 13.5 0.8 0.69 9.7 0.2 2.4 2 0 0 2 2 2 0 KIP1-like protein GSH-S_ATP PF02955.11 EOO03515.1 - 0.089 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Pro_isomerase PF00160.16 EOO03516.1 - 2.5e-46 157.7 0.4 4.1e-46 157.0 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EOO03516.1 - 3.2e-12 45.9 6.5 1.6e-07 30.8 0.7 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EOO03516.1 - 5.3e-08 32.1 5.9 6.8e-05 22.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EOO03516.1 - 1.5e-06 27.5 4.5 0.00017 21.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EOO03516.1 - 0.00013 21.8 3.0 0.00083 19.2 1.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EOO03516.1 - 0.00041 19.9 1.0 0.0011 18.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EOO03516.1 - 0.0025 17.6 1.2 0.0071 16.1 0.4 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EOO03516.1 - 0.0027 18.3 7.2 0.057 14.1 2.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EOO03516.1 - 0.061 13.8 0.3 0.061 13.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EOO03516.1 - 0.1 12.4 2.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EOO03516.1 - 0.22 12.2 5.1 0.72 10.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GCS PF03074.11 EOO03517.1 - 1.6e-130 435.5 0.0 2.5e-130 434.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Sigma70_r4 PF04545.11 EOO03517.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PPR_2 PF13041.1 EOO03518.1 - 0.0037 17.2 1.5 0.5 10.3 0.0 3.4 1 1 2 3 3 3 1 PPR repeat family PPR PF01535.15 EOO03518.1 - 0.017 15.0 6.8 1.1 9.3 0.0 4.2 5 0 0 5 5 5 0 PPR repeat SLAC1 PF03595.12 EOO03519.1 - 7.7e-73 244.9 42.4 9.3e-73 244.7 29.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_3 PF00933.16 EOO03520.1 - 5.7e-79 265.1 0.0 9.3e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO03520.1 - 1.3e-69 234.2 0.0 3.2e-69 232.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO03520.1 - 1.7e-25 88.7 1.9 4.8e-25 87.2 1.3 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EOO03520.1 - 8.9e-17 61.0 0.2 2.5e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 PA14 domain CARDB PF07705.6 EOO03520.1 - 0.013 15.5 0.3 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 CARDB CTP_transf_2 PF01467.21 EOO03521.1 - 8.7e-22 77.8 0.0 1.5e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Ion_trans PF00520.26 EOO03522.1 - 2.1e-09 36.9 3.2 3.8e-09 36.0 2.2 1.3 1 0 0 1 1 1 1 Ion transport protein bZIP_1 PF00170.16 EOO03522.1 - 0.0028 17.5 1.9 0.0052 16.7 1.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 EOO03522.1 - 0.0095 15.3 0.3 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 EOO03522.1 - 0.013 15.2 3.4 0.04 13.7 2.4 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Herpes_BLRF2 PF05812.7 EOO03522.1 - 0.025 14.3 0.5 0.036 13.8 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 EOO03522.1 - 0.12 12.7 0.3 0.18 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Med9 PF07544.8 EOO03522.1 - 0.12 12.1 1.0 0.18 11.5 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Ran_BP1 PF00638.13 EOO03524.1 - 5.9e-17 61.8 0.1 1.3e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 RanBP1 domain UQ_con PF00179.21 EOO03525.1 - 5.6e-49 165.1 0.1 6.3e-49 165.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO03525.1 - 5.1e-05 23.0 0.0 7.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO03525.1 - 0.11 12.3 1.3 0.2 11.5 0.9 1.8 1 1 0 1 1 1 0 RWD domain MFS_1 PF07690.11 EOO03527.1 - 3e-31 108.4 22.2 4.1e-31 107.9 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EOO03528.1 - 4.5e-26 89.7 6.4 9.6e-07 28.4 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Bacteriocin_IIi PF11758.3 EOO03528.1 - 0.041 13.5 0.1 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin DUF1996 PF09362.5 EOO03529.1 - 4.7e-76 255.5 10.6 3.7e-75 252.6 4.7 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1996) PLDc PF00614.17 EOO03532.1 - 1.7e-16 59.4 1.5 5.6e-07 29.1 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EOO03532.1 - 5e-13 48.9 0.1 3.2e-08 33.3 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EOO03532.1 - 9e-07 28.6 0.3 1.3e-05 24.9 0.2 2.6 1 1 0 1 1 1 1 PX domain MatE PF01554.13 EOO03533.1 - 7.4e-30 103.7 6.2 1.1e-28 99.8 0.6 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EOO03533.1 - 2.3e-06 27.4 4.7 2.3e-06 27.4 3.3 3.3 2 2 1 3 3 3 3 Polysaccharide biosynthesis C-terminal domain S4 PF01479.20 EOO03534.1 - 4.5e-13 48.4 0.0 8.3e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EOO03534.1 - 3.3e-12 46.6 0.7 5.6e-12 45.8 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain UPF0302 PF08864.5 EOO03534.1 - 0.071 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 UPF0302 domain AA_permease PF00324.16 EOO03535.1 - 1.4e-91 307.2 38.3 1.9e-91 306.8 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO03535.1 - 1.5e-34 119.2 43.6 1.5e-34 119.2 30.2 1.3 2 0 0 2 2 2 1 Amino acid permease PrgI PF12666.2 EOO03535.1 - 0.45 10.6 0.0 0.45 10.6 0.0 4.5 5 1 1 6 6 6 0 PrgI family protein Abhydrolase_6 PF12697.2 EOO03536.1 - 1.2e-22 80.8 0.6 3.5e-22 79.3 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO03536.1 - 1e-08 35.0 0.1 1.3e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO03536.1 - 8.5e-06 25.5 0.0 1.3e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EOO03536.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EOO03536.1 - 0.014 15.5 0.1 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.7 EOO03536.1 - 0.03 13.8 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase Ser_hydrolase PF06821.8 EOO03536.1 - 0.035 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF1253 PF06862.7 EOO03537.1 - 2.9e-164 546.6 0.0 3.7e-164 546.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Cullin_Nedd8 PF10557.4 EOO03538.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain DUF2580 PF10824.3 EOO03538.1 - 2.2 8.6 21.0 4.5 7.6 10.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) DUF883 PF05957.8 EOO03538.1 - 7.3 7.0 18.9 9.9 6.6 4.9 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) GFO_IDH_MocA PF01408.17 EOO03539.1 - 3.1e-14 53.4 0.0 5.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EOO03539.1 - 0.00091 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain YLP PF02757.12 EOO03539.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 YLP motif Pyridoxal_deC PF00282.14 EOO03540.1 - 1.9e-22 79.2 0.0 2.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EOO03540.1 - 2.5e-05 23.5 0.0 6.5e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EOO03540.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II adh_short PF00106.20 EOO03541.1 - 2.5e-10 40.5 0.1 4.8e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03541.1 - 0.0048 16.6 0.4 0.0081 15.9 0.2 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03541.1 - 0.0087 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L44 PF00935.14 EOO03542.1 - 2.4e-32 110.7 7.3 3.2e-32 110.3 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Fungal_trans_2 PF11951.3 EOO03543.1 - 1.2e-10 40.6 0.4 3.3e-10 39.1 0.0 1.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain DSBA PF01323.15 EOO03544.1 - 6.9e-22 77.9 0.0 7.9e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain KorB PF08535.5 EOO03544.1 - 0.1 12.7 0.1 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 KorB domain cwf18 PF08315.7 EOO03545.1 - 3.6e-44 150.3 7.0 3.6e-44 150.3 4.8 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor ECH PF00378.15 EOO03546.1 - 6.2e-12 45.1 0.0 8.2e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_C71 PF12386.3 EOO03546.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei V-SNARE PF05008.10 EOO03548.1 - 0.06 13.5 2.9 0.46 10.6 2.0 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.16 EOO03548.1 - 0.18 12.1 7.8 0.18 12.0 3.7 2.1 2 1 0 2 2 2 0 Spectrin repeat GlnD_UR_UTase PF08335.6 EOO03548.1 - 0.21 11.4 2.3 0.17 11.7 0.3 1.7 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Mnd1 PF03962.10 EOO03548.1 - 0.5 10.0 6.0 0.072 12.7 1.3 1.6 2 1 1 3 3 3 0 Mnd1 family PilJ PF13675.1 EOO03548.1 - 2.8 8.2 12.0 11 6.3 1.4 2.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FAD_binding_3 PF01494.14 EOO03550.1 - 1.2e-19 70.6 0.0 2.8e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EOO03550.1 - 4.7e-09 35.6 0.9 0.0027 16.6 0.0 2.9 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EOO03550.1 - 2e-05 24.8 0.2 0.016 15.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO03550.1 - 0.00097 17.7 0.6 0.0064 15.0 0.4 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EOO03550.1 - 0.001 18.0 0.2 0.16 10.8 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EOO03550.1 - 0.0023 17.9 0.1 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EOO03550.1 - 0.0051 16.8 0.1 0.075 13.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EOO03550.1 - 0.017 13.9 0.0 0.55 9.0 0.0 2.5 3 0 0 3 3 3 0 Squalene epoxidase NAD_binding_9 PF13454.1 EOO03550.1 - 0.034 13.9 0.5 5.1 6.8 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EOO03550.1 - 0.039 12.8 0.0 0.43 9.4 0.0 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EOO03550.1 - 0.042 13.7 0.1 0.16 11.7 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EOO03550.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 EOO03550.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thiolase_C PF02803.13 EOO03551.1 - 4.6e-11 42.2 1.1 1.2e-10 40.8 0.1 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EOO03551.1 - 4.9e-06 26.1 0.2 0.00055 19.5 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EOO03551.1 - 0.0002 20.4 1.1 0.00043 19.3 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain SpoVAD PF07451.6 EOO03551.1 - 0.0018 16.7 0.7 0.21 10.0 0.1 2.3 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 EOO03551.1 - 0.0019 17.7 0.2 0.0037 16.7 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EOO03551.1 - 0.013 15.3 0.8 1.2 9.0 0.3 3.4 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain PseudoU_synth_1 PF01416.15 EOO03552.1 - 1.4e-31 109.0 0.0 3.7e-22 78.7 0.0 3.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase BCDHK_Adom3 PF10436.4 EOO03553.1 - 3.8e-69 231.4 0.0 5.9e-69 230.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EOO03553.1 - 1.7e-14 53.4 0.0 5.2e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EOO03553.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.16 EOO03554.1 - 1.5e-16 60.5 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO03554.1 - 6.5e-11 41.4 0.0 1.4e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EOO03554.1 - 4.9e-10 39.7 0.3 2.3e-09 37.5 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EOO03554.1 - 2.1e-08 33.4 0.0 1.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EOO03554.1 - 7.9e-05 22.6 0.1 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EOO03554.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 EOO03554.1 - 0.033 13.8 0.0 0.079 12.6 0.0 1.6 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EOO03554.1 - 0.085 11.7 0.0 0.19 10.5 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Thr_synth_N PF14821.1 EOO03555.1 - 5.6e-27 93.5 0.0 1.2e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EOO03555.1 - 1.2e-20 73.9 0.0 1.3e-19 70.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CCCH PF00642.19 EOO03556.1 - 3.8e-06 26.4 0.8 3.8e-06 26.4 0.6 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) EF-hand_6 PF13405.1 EOO03557.1 - 7.9e-08 31.5 0.1 0.011 15.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EOO03557.1 - 2.1e-05 23.4 0.2 0.00059 18.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EOO03557.1 - 3e-05 23.1 0.0 0.0004 19.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EOO03557.1 - 0.00056 19.9 1.5 0.00056 19.9 1.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EOO03557.1 - 0.0082 15.7 0.4 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair Fungal_trans PF04082.13 EOO03558.1 - 2.7e-17 62.4 0.2 4.5e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO03558.1 - 2.3e-06 27.3 18.9 5.6e-06 26.1 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2407_C PF13373.1 EOO03559.1 - 3.5e-33 114.4 0.1 4.6e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EOO03559.1 - 1.3e-26 92.6 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain VCBS PF13517.1 EOO03560.1 - 2.2e-32 111.2 74.4 3.7e-10 40.0 5.0 10.2 4 3 7 11 11 11 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO03560.1 - 1.1e-15 56.8 63.7 0.00039 20.0 1.9 9.3 9 0 0 9 9 9 7 FG-GAP repeat Lipase_GDSL PF00657.17 EOO03560.1 - 7.4e-11 42.3 0.1 1.9e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 EOO03560.1 - 1.7e-10 40.6 14.9 0.066 12.6 0.1 6.3 4 2 3 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 EOO03560.1 - 7.6e-08 32.6 0.3 3.2e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EOO03560.1 - 0.00018 21.3 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.17 EOO03561.1 - 5e-09 35.6 0.0 2.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03561.1 - 6.8e-08 32.3 0.0 9.7e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03561.1 - 0.00025 20.8 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EOO03561.1 - 0.00036 20.9 1.4 0.00036 20.9 0.9 3.2 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RNA12 PF10443.4 EOO03562.1 - 7.9e-167 555.1 3.2 1e-166 554.7 2.2 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EOO03562.1 - 5.7e-05 22.9 0.1 0.00039 20.1 0.1 2.3 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EOO03562.1 - 9.1e-05 22.0 0.0 0.00087 18.8 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EOO03562.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_5 PF13893.1 EOO03562.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FTA4 PF13093.1 EOO03562.1 - 0.038 13.4 0.7 0.092 12.1 0.5 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RRM_6 PF14259.1 EOO03562.1 - 0.071 13.1 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SnoaL_2 PF12680.2 EOO03563.1 - 8.4e-05 22.9 0.0 0.0003 21.1 0.0 1.9 1 1 0 1 1 1 1 SnoaL-like domain Peptidase_M41 PF01434.13 EOO03564.1 - 1e-58 198.2 0.1 1.8e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EOO03564.1 - 4.7e-43 146.5 0.0 1.3e-42 145.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.20 EOO03564.1 - 1.1e-17 64.4 0.3 4.5e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO03564.1 - 4.9e-08 32.8 0.0 1.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 KR domain AAA_17 PF13207.1 EOO03564.1 - 4.6e-06 27.4 0.0 4.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO03564.1 - 1.5e-05 25.0 2.8 0.00031 20.7 0.5 3.7 3 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EOO03564.1 - 2.1e-05 24.2 0.0 6.9e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EOO03564.1 - 4.2e-05 22.4 0.0 8.2e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EOO03564.1 - 9.2e-05 22.5 0.2 0.043 13.9 0.0 2.9 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EOO03564.1 - 0.00041 19.4 0.0 0.00089 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EOO03564.1 - 0.0018 18.1 0.0 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EOO03564.1 - 0.0022 17.4 0.1 0.0058 16.0 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EOO03564.1 - 0.0048 16.0 1.0 0.026 13.6 0.2 2.3 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EOO03564.1 - 0.007 16.3 0.1 0.039 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EOO03564.1 - 0.008 16.0 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EOO03564.1 - 0.0099 15.6 0.5 0.0099 15.6 0.4 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EOO03564.1 - 0.012 15.0 1.1 0.11 11.8 0.2 2.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EOO03564.1 - 0.017 14.3 0.3 0.04 13.0 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EOO03564.1 - 0.024 14.9 0.1 0.075 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EOO03564.1 - 0.031 14.1 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EOO03564.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EOO03564.1 - 0.1 12.2 1.1 1.6 8.3 0.1 2.7 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.17 EOO03564.1 - 0.18 10.6 0.1 7.2 5.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Pirin PF02678.11 EOO03565.1 - 5e-33 113.1 0.1 9.3e-33 112.3 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EOO03565.1 - 1.7e-27 95.5 0.0 1.4e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EOO03565.1 - 1.2e-07 31.1 2.0 2.3e-05 23.8 0.5 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EOO03565.1 - 0.0014 18.0 0.4 1.2 8.5 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_7 PF12973.2 EOO03565.1 - 0.087 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain DUF2183 PF09949.4 EOO03566.1 - 5.4e-20 71.1 0.1 1e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) YPEB PF14620.1 EOO03566.1 - 0.039 12.9 0.2 0.059 12.3 0.1 1.1 1 0 0 1 1 1 0 YpeB sporulation Pribosyl_synth PF14572.1 EOO03567.1 - 2.8e-40 138.0 3.4 2.2e-34 118.8 1.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EOO03567.1 - 5.9e-40 135.6 0.3 1.7e-39 134.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EOO03567.1 - 1e-10 41.4 0.4 3.4e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EOO03567.1 - 0.018 14.2 0.2 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF218 PF02698.12 EOO03567.1 - 0.059 12.8 0.0 0.3 10.5 0.0 2.0 1 1 0 1 1 1 0 DUF218 domain CDO_I PF05995.7 EOO03567.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I HSF_DNA-bind PF00447.12 EOO03569.1 - 1.3e-27 96.0 0.7 1.7e-27 95.6 0.5 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Retinal PF15449.1 EOO03569.1 - 0.21 9.1 2.7 0.21 9.2 1.9 1.0 1 0 0 1 1 1 0 Retinal protein DUF972 PF06156.8 EOO03570.1 - 0.00032 20.9 15.2 0.054 13.8 0.4 3.6 1 1 3 4 4 4 2 Protein of unknown function (DUF972) GAS PF13851.1 EOO03570.1 - 0.00065 18.9 18.6 0.0027 16.9 6.3 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EOO03570.1 - 0.00088 19.1 11.1 0.00088 19.1 7.7 2.4 1 1 1 2 2 2 1 Tropomyosin like ADIP PF11559.3 EOO03570.1 - 0.0013 18.6 4.8 0.0013 18.6 3.3 3.3 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EOO03570.1 - 0.0013 18.5 5.3 0.0013 18.5 3.7 2.5 2 2 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EOO03570.1 - 0.0013 18.9 5.9 0.0013 18.9 4.1 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF904) DUF2968 PF11180.3 EOO03570.1 - 0.0014 18.0 4.9 0.0014 18.0 3.4 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF2968) Tropomyosin PF00261.15 EOO03570.1 - 0.0026 16.8 17.5 0.015 14.3 7.4 2.3 1 1 0 2 2 2 1 Tropomyosin TBPIP PF07106.8 EOO03570.1 - 0.0033 16.9 12.9 0.043 13.3 1.7 2.8 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tup_N PF08581.5 EOO03570.1 - 0.0039 17.3 7.1 0.63 10.2 0.2 2.6 2 1 0 2 2 2 2 Tup N-terminal TACC PF05010.9 EOO03570.1 - 0.0056 16.4 4.1 0.0056 16.4 2.8 2.2 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) HALZ PF02183.13 EOO03570.1 - 0.0062 16.2 14.7 0.12 12.1 0.3 4.4 2 1 2 4 4 4 1 Homeobox associated leucine zipper FlxA PF14282.1 EOO03570.1 - 0.0072 16.2 4.5 0.022 14.6 1.6 2.1 1 1 1 2 2 2 2 FlxA-like protein FlaC_arch PF05377.6 EOO03570.1 - 0.0074 16.1 1.5 1.1 9.1 0.0 3.2 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) OmpH PF03938.9 EOO03570.1 - 0.0086 16.0 4.7 0.0086 16.0 3.2 2.1 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Bacillus_HBL PF05791.6 EOO03570.1 - 0.0093 15.3 2.2 0.01 15.1 0.5 1.8 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) TSC22 PF01166.13 EOO03570.1 - 0.011 15.6 12.7 0.73 9.8 0.3 4.4 3 2 2 5 5 4 0 TSC-22/dip/bun family DUF2987 PF11205.3 EOO03570.1 - 0.021 14.4 0.2 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) Reo_sigmaC PF04582.7 EOO03570.1 - 0.023 13.8 0.6 0.033 13.3 0.4 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EOO03570.1 - 0.031 14.2 17.2 1.6 8.7 1.5 4.8 1 1 5 6 6 6 0 bZIP transcription factor Utp12 PF04003.7 EOO03570.1 - 0.055 13.3 1.7 1.5 8.7 0.5 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family Microtub_assoc PF07989.6 EOO03570.1 - 0.06 13.1 3.6 2.2 8.1 0.1 2.9 1 1 0 2 2 2 0 Microtubule associated LPP PF04728.8 EOO03570.1 - 0.067 12.9 2.1 0.47 10.2 0.1 2.8 1 1 1 3 3 2 0 Lipoprotein leucine-zipper APG6 PF04111.7 EOO03570.1 - 0.079 12.0 19.4 0.17 10.8 2.3 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Spherulin4 PF12138.3 EOO03570.1 - 0.084 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 Seryl_tRNA_N PF02403.17 EOO03570.1 - 0.09 12.7 11.6 0.059 13.3 3.8 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.3 EOO03570.1 - 0.1 11.1 0.7 0.13 10.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Baculo_PEP_C PF04513.7 EOO03570.1 - 0.11 12.2 3.9 0.5 10.1 2.6 2.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.6 EOO03570.1 - 0.12 12.2 23.9 0.13 12.1 0.8 3.2 1 1 1 3 3 3 0 Rabaptin-like protein TMF_DNA_bd PF12329.3 EOO03570.1 - 0.18 11.6 15.4 0.17 11.6 0.4 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 EOO03570.1 - 0.2 11.5 0.6 1.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Kinetocho_Slk19 PF12709.2 EOO03570.1 - 0.2 11.7 11.6 7.4 6.7 0.3 3.7 1 1 3 4 4 3 0 Central kinetochore-associated DivIC PF04977.10 EOO03570.1 - 0.21 11.1 21.0 0.098 12.1 0.6 4.2 1 1 3 4 4 4 0 Septum formation initiator Herpes_BLRF2 PF05812.7 EOO03570.1 - 0.23 11.2 10.6 1.9 8.3 0.7 3.5 2 2 2 4 4 4 0 Herpesvirus BLRF2 protein TMPIT PF07851.8 EOO03570.1 - 0.26 10.2 3.1 0.38 9.7 2.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein Seadorna_VP6 PF07407.6 EOO03570.1 - 0.28 9.8 2.4 0.42 9.3 0.3 1.9 1 1 1 2 2 2 0 Seadornavirus VP6 protein IFT57 PF10498.4 EOO03570.1 - 0.35 9.5 8.9 0.12 11.0 4.3 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 EOO03570.1 - 0.53 9.8 22.6 8.6 5.9 15.4 2.1 1 1 0 1 1 1 0 IncA protein DUF4201 PF13870.1 EOO03570.1 - 0.58 9.5 17.8 0.12 11.7 2.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.4 EOO03570.1 - 0.58 10.3 7.0 1.4 9.1 1.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EOO03570.1 - 0.59 8.4 5.5 0.23 9.8 2.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FUSC PF04632.7 EOO03570.1 - 0.74 8.1 14.7 0.94 7.8 10.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Speriolin_N PF15058.1 EOO03570.1 - 0.78 9.6 4.2 0.92 9.3 0.1 2.1 1 1 1 2 2 2 0 Speriolin N terminus DUF4407 PF14362.1 EOO03570.1 - 0.8 8.6 13.6 1.3 7.9 9.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.9 EOO03570.1 - 0.89 9.1 11.3 0.085 12.4 2.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Prominin PF05478.6 EOO03570.1 - 1 6.7 5.4 0.84 7.0 0.4 1.9 1 1 1 2 2 2 0 Prominin Syntaxin PF00804.20 EOO03570.1 - 1.3 9.2 8.6 5.3 7.2 3.3 2.6 1 1 1 2 2 2 0 Syntaxin COG2 PF06148.6 EOO03570.1 - 1.6 8.5 6.3 1.5 8.7 1.6 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.15 EOO03570.1 - 2.6 7.8 13.4 1.3 8.7 0.5 3.5 1 1 1 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 EOO03570.1 - 2.9 7.9 9.6 3.2 7.8 2.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CASP_C PF08172.7 EOO03570.1 - 3.1 6.7 14.6 1 8.3 0.3 3.2 1 1 2 3 3 3 0 CASP C terminal Jnk-SapK_ap_N PF09744.4 EOO03570.1 - 3.3 7.6 18.0 0.11 12.4 1.2 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.10 EOO03570.1 - 3.5 7.5 22.6 0.56 10.0 1.0 5.0 2 2 1 4 4 4 0 Basic region leucine zipper SlyX PF04102.7 EOO03570.1 - 3.5 8.0 13.9 1.4 9.3 1.5 3.5 1 1 2 3 3 3 0 SlyX DUF3450 PF11932.3 EOO03570.1 - 3.6 6.7 16.0 0.15 11.3 3.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.1 EOO03570.1 - 4 7.5 10.9 35 4.4 7.1 2.5 1 1 0 1 1 1 0 Syntaxin-like protein Atg14 PF10186.4 EOO03570.1 - 4.3 6.1 23.5 0.047 12.6 3.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 EOO03570.1 - 5.2 6.8 15.9 1.5 8.5 5.5 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Bap31 PF05529.7 EOO03570.1 - 6.5 6.1 8.7 4.8 6.5 0.5 2.5 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like DUF2681 PF10883.3 EOO03570.1 - 7.1 6.9 15.1 2.3 8.4 1.4 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2681) DUF721 PF05258.7 EOO03570.1 - 7.8 6.7 8.4 5.5 7.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF721) YlqD PF11068.3 EOO03570.1 - 8.7 6.3 13.9 2.1 8.3 4.1 2.8 1 1 2 3 3 3 0 YlqD protein Spc24 PF08286.6 EOO03570.1 - 8.8 6.0 12.1 2.1 8.0 0.8 3.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HAUS6_N PF14661.1 EOO03570.1 - 9.5 5.4 17.5 2.3 7.5 7.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DENN PF02141.16 EOO03571.1 - 9.4e-40 136.3 0.1 1.6e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EOO03571.1 - 7.8e-06 25.7 0.0 3.2e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EOO03571.1 - 0.0021 18.3 3.9 0.0021 18.3 2.7 2.4 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3135 PF11333.3 EOO03571.1 - 6.4 7.0 9.0 0.51 10.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Hydant_A_N PF05378.8 EOO03572.1 - 6.5e-56 188.6 0.0 8.4e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.13 EOO03572.1 - 4e-18 65.5 0.0 1.2e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Pkinase PF00069.20 EOO03573.1 - 1.4e-62 211.2 0.0 1.8e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03573.1 - 1.4e-24 86.5 0.0 2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO03573.1 - 0.0033 16.4 0.0 0.48 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RNase_HII PF01351.13 EOO03574.1 - 1.6e-45 155.2 0.0 2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Steroid_dh PF02544.11 EOO03575.1 - 2e-19 69.8 1.6 4.8e-18 65.3 1.1 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EOO03575.1 - 7.8e-05 22.0 0.4 0.00019 20.8 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Glyoxalase_2 PF12681.2 EOO03575.1 - 0.00043 20.8 0.0 0.0012 19.3 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain HMA PF00403.21 EOO03576.1 - 1.2e-15 57.4 1.2 1.2e-15 57.3 0.4 1.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Glycos_transf_1 PF00534.15 EOO03578.1 - 1.7e-22 79.6 0.0 2.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EOO03578.1 - 9.4e-09 35.5 0.0 6.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 rRNA_proc-arch PF13234.1 EOO03579.1 - 2.8e-94 315.2 0.0 6e-94 314.1 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EOO03579.1 - 4.2e-60 202.0 2.8 8.7e-60 201.0 1.9 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EOO03579.1 - 1.7e-21 76.4 0.0 5.4e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO03579.1 - 1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO03579.1 - 0.0044 16.8 0.2 0.091 12.5 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EOO03579.1 - 0.02 13.8 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Prp19 PF08606.6 EOO03579.1 - 0.027 14.2 0.9 6.6 6.5 0.1 2.9 2 0 0 2 2 2 0 Prp19/Pso4-like DASH_Dad1 PF08649.5 EOO03580.1 - 4.1e-25 87.2 0.6 4.9e-25 86.9 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 LSM PF01423.17 EOO03581.1 - 1.6e-19 69.2 0.2 2e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Cutinase PF01083.17 EOO03582.1 - 6.1e-28 97.7 0.0 6.1e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Cutinase SipA PF09052.5 EOO03582.1 - 5.8 5.1 17.4 7.6 4.7 12.0 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A Aminotran_1_2 PF00155.16 EOO03583.1 - 7.2e-68 229.1 0.0 8.2e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EOO03583.1 - 4.9e-06 25.9 0.0 6.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EOO03583.1 - 0.00045 19.3 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EOO03583.1 - 0.00052 18.4 0.0 0.00088 17.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EOO03583.1 - 0.032 12.9 0.0 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Pyridox_oxidase PF01243.15 EOO03584.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_60s PF00428.14 EOO03584.1 - 0.061 13.7 4.4 0.089 13.2 2.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein APH PF01636.18 EOO03585.1 - 0.0013 18.4 0.2 0.002 17.8 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EOO03585.1 - 0.068 12.7 0.5 0.15 11.6 0.3 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EOO03586.1 - 2e-65 220.6 0.0 2.2e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EOO03586.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EOO03586.1 - 0.0039 15.8 0.0 0.0057 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) His_Phos_2 PF00328.17 EOO03587.1 - 0.019 14.3 0.1 0.028 13.7 0.1 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) EST1 PF10374.4 EOO03587.1 - 0.096 12.6 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 DUF3482 PF11981.3 EOO03587.1 - 0.26 10.4 8.3 0.45 9.6 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Tcf25 PF04910.9 EOO03588.1 - 2.6e-68 230.5 0.9 3.1e-68 230.3 0.1 1.5 2 0 0 2 2 2 1 Transcriptional repressor TCF25 HSP90 PF00183.13 EOO03588.1 - 2.7 6.2 9.2 8.5 4.6 0.0 2.4 2 0 0 2 2 2 0 Hsp90 protein Pribosyl_synth PF14572.1 EOO03589.1 - 4.9e-43 147.0 2.3 8.4e-37 126.6 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EOO03589.1 - 1.8e-28 98.5 0.0 7.5e-28 96.6 0.0 2.0 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EOO03589.1 - 3.8e-12 46.0 0.2 3.8e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EOO03589.1 - 0.043 13.0 0.2 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_61 PF03443.9 EOO03590.1 - 1.9e-44 152.1 0.0 2.3e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Epimerase PF01370.16 EOO03591.1 - 1.4e-12 47.6 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO03591.1 - 1.6e-10 40.1 0.0 2.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EOO03591.1 - 6.3e-07 29.5 1.5 1.5e-06 28.3 1.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EOO03591.1 - 0.0022 16.9 0.1 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EOO03591.1 - 0.039 14.3 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EOO03591.1 - 0.045 13.6 0.1 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Lactonase PF10282.4 EOO03592.1 - 4.6e-38 131.1 0.0 6.5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller tRNA_U5-meth_tr PF05958.6 EOO03593.1 - 2.2e-09 36.4 0.0 2.4e-07 29.7 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EOO03593.1 - 2.3e-07 30.4 0.0 4.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EOO03593.1 - 6.4e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 EOO03593.1 - 6.7e-05 23.4 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EOO03593.1 - 0.00039 19.6 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EOO03593.1 - 0.00039 20.4 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EOO03593.1 - 0.00052 19.6 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.11 EOO03593.1 - 0.014 14.2 0.1 0.026 13.4 0.0 1.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EOO03593.1 - 0.023 14.3 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.10 EOO03593.1 - 0.047 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EOO03593.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EOO03593.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ADH_N PF08240.7 EOO03594.1 - 3.8e-30 103.8 0.2 7.2e-30 102.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO03594.1 - 1.4e-25 89.3 0.3 2.4e-25 88.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HSP70 PF00012.15 EOO03595.1 - 8.3e-270 895.8 5.7 9.5e-270 895.6 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EOO03595.1 - 5.9e-17 61.2 0.0 6.8e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EOO03595.1 - 0.0034 17.0 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EOO03595.1 - 0.0093 15.0 0.0 0.039 13.0 0.0 2.0 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.6 EOO03595.1 - 0.045 12.6 0.0 0.094 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 EOO03595.1 - 0.11 12.2 5.1 4.2 7.2 2.0 3.3 2 1 0 2 2 2 0 Cell division protein FtsA DUF4404 PF14357.1 EOO03595.1 - 1.4 9.3 5.0 2.2 8.7 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RNA_pol_Rpb4 PF03874.11 EOO03596.1 - 1e-22 80.3 0.2 1.2e-22 80.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Mif2_N PF15624.1 EOO03597.1 - 1.8e-35 122.4 0.4 1.8e-35 122.4 0.3 3.4 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EOO03597.1 - 6.7e-33 112.5 0.3 1.1e-32 111.8 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EOO03597.1 - 2e-06 27.2 0.0 5.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Pyridoxal_deC PF00282.14 EOO03598.1 - 7.1e-18 64.2 0.0 1e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EOO03598.1 - 0.00091 18.0 0.0 0.0022 16.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EOO03598.1 - 0.0078 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family LGT PF01790.13 EOO03598.1 - 0.1 11.5 0.5 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Prolipoprotein diacylglyceryl transferase TRF PF08558.5 EOO03599.1 - 7.1e-20 71.3 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EOO03599.1 - 4e-07 29.9 0.1 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EOO03599.1 - 0.0032 17.5 0.0 0.0081 16.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ORC6 PF05460.8 EOO03600.1 - 0.0077 15.3 2.0 0.011 14.8 1.4 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) BBP1_N PF15271.1 EOO03600.1 - 0.0082 16.5 0.3 0.0082 16.5 0.2 1.7 2 0 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein DUF3128 PF11326.3 EOO03601.1 - 7.2e-25 86.9 0.3 1e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CS PF04969.11 EOO03602.1 - 1.7e-11 44.5 0.1 2.6e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 CS domain Nop14 PF04147.7 EOO03602.1 - 1.6 6.5 9.7 1.9 6.2 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.17 EOO03604.1 - 2.9e-188 625.8 0.1 3.3e-188 625.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Alg14 PF08660.6 EOO03605.1 - 2.2e-40 138.4 0.0 3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DBR1 PF05011.8 EOO03606.1 - 1.3e-48 164.5 0.0 2.3e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EOO03606.1 - 1.2e-08 34.5 0.1 2.8e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Asparaginase_2 PF01112.13 EOO03607.1 - 1.2e-35 122.8 4.7 7.3e-21 74.1 0.1 2.3 2 0 0 2 2 2 2 Asparaginase PRMT5 PF05185.11 EOO03608.1 - 3.7e-162 540.3 0.0 4.6e-162 540.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MRP-S25 PF13741.1 EOO03609.1 - 3.8e-70 235.9 8.9 9.9e-66 221.5 2.2 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EOO03609.1 - 0.16 11.8 4.0 1.3 8.9 2.8 2.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 RasGEF PF00617.14 EOO03610.1 - 5.7e-50 169.6 0.0 9.2e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EOO03610.1 - 7.9e-14 51.6 0.3 1.5e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif MFS_1 PF07690.11 EOO03611.1 - 1.5 7.4 29.2 6.9 5.2 20.1 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Y_phosphatase2 PF03162.8 EOO03612.1 - 9.5e-46 155.1 0.0 1.4e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EOO03612.1 - 9.1e-11 42.2 0.0 5.6e-10 39.7 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EOO03612.1 - 5.9e-05 22.6 0.1 9.7e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EOO03612.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribonuclease_3 PF00636.21 EOO03613.1 - 8.9e-38 129.2 0.0 1.9e-17 63.7 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EOO03613.1 - 1.9e-22 79.6 0.0 1.4e-08 34.7 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EOO03613.1 - 3.2e-17 62.0 0.0 1e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EOO03613.1 - 5.4e-17 61.4 0.0 1.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 EOO03614.1 - 1.4e-21 75.4 14.7 0.0005 19.8 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EOO03614.1 - 0.0022 18.2 1.1 0.29 11.4 0.1 3.9 3 1 1 4 4 4 1 PQQ-like domain Nup160 PF11715.3 EOO03614.1 - 0.0087 14.2 0.2 0.81 7.7 0.0 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF627 PF04781.7 EOO03614.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Syntaxin_2 PF14523.1 EOO03616.1 - 3.1e-27 94.5 7.1 4.5e-27 94.0 2.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EOO03616.1 - 4.3e-18 64.7 1.8 1.3e-17 63.1 1.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EOO03616.1 - 0.00036 20.6 0.4 0.00036 20.6 0.3 2.8 1 1 1 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EOO03616.1 - 0.0025 17.3 0.1 0.011 15.3 0.1 2.1 2 0 0 2 2 2 1 Synaptobrevin Gp-FAR-1 PF05823.7 EOO03616.1 - 0.022 14.7 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF883 PF05957.8 EOO03616.1 - 0.065 13.6 9.7 0.78 10.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 EOO03616.1 - 0.12 12.1 3.3 6.4 6.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 EOO03616.1 - 0.26 10.8 10.0 0.14 11.6 1.5 2.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.3 EOO03616.1 - 0.76 8.9 14.5 0.061 12.5 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) T2SF PF00482.18 EOO03616.1 - 1.3 8.9 4.6 0.32 10.9 0.2 2.2 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Mnd1 PF03962.10 EOO03616.1 - 3 7.4 7.9 0.58 9.7 0.1 2.5 1 1 2 3 3 3 0 Mnd1 family RHD3 PF05879.7 EOO03617.1 - 0 1063.3 0.0 0 1063.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EOO03617.1 - 1.1e-07 31.2 0.1 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EOO03617.1 - 9.8e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EOO03617.1 - 0.00013 21.9 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EOO03617.1 - 0.00036 20.5 0.9 0.00082 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EOO03617.1 - 0.00041 20.8 0.1 0.00082 19.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EOO03617.1 - 0.02 13.9 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 Septin Cys_Met_Meta_PP PF01053.15 EOO03617.1 - 0.022 13.0 0.2 0.035 12.4 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3669 PF12417.3 EOO03617.1 - 0.11 12.2 0.8 0.99 9.1 0.0 2.7 2 0 0 2 2 2 0 Zinc finger protein Carn_acyltransf PF00755.15 EOO03618.1 - 3.1e-166 553.9 0.0 5.5e-151 503.6 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase CTP_transf_1 PF01148.15 EOO03619.1 - 8.5e-15 55.1 12.3 9e-13 48.4 4.8 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF4129 PF13559.1 EOO03620.1 - 0.0093 15.9 0.3 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) YrvL PF14184.1 EOO03620.1 - 0.2 11.4 2.4 0.46 10.3 1.7 1.5 1 1 0 1 1 1 0 Regulatory protein YrvL NICE-3 PF07406.6 EOO03620.1 - 1.9 7.9 4.1 10 5.5 0.0 2.6 3 0 0 3 3 3 0 NICE-3 protein DEAD PF00270.24 EOO03621.1 - 7.8e-34 116.6 0.0 2.9e-33 114.7 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EOO03621.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) MarR_2 PF12802.2 EOO03621.1 - 0.02 14.5 0.2 1.5 8.5 0.0 3.3 3 0 0 3 3 3 0 MarR family AAA_22 PF13401.1 EOO03621.1 - 0.17 12.0 1.2 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 EOO03621.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Tfb4 PF03850.9 EOO03622.1 - 5.4e-85 284.9 12.1 4e-62 209.9 0.5 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 Rogdi_lz PF10259.4 EOO03622.1 - 0.059 12.4 0.4 0.088 11.8 0.3 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Smg4_UPF3 PF03467.10 EOO03623.1 - 4e-31 108.3 0.0 1.4e-30 106.5 0.0 2.0 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EOO03623.1 - 1.7e-06 27.5 0.0 4e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03623.1 - 3.4e-06 26.9 0.0 0.00017 21.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03623.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 EOO03624.1 - 3.6e-79 264.8 0.4 3.6e-79 264.8 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EOO03624.1 - 1.5e-26 92.8 0.6 2.7e-26 91.9 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EOO03624.1 - 1.5e-07 30.9 0.2 4e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EOO03624.1 - 2.1e-05 24.1 1.2 0.00082 18.9 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EOO03624.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 EOO03624.1 - 0.03 13.4 0.3 0.056 12.5 0.2 1.4 1 0 0 1 1 1 0 Periplasmic binding protein p450 PF00067.17 EOO03625.1 - 6.3e-50 170.0 0.0 8.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cerato-platanin PF07249.7 EOO03625.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin Perilipin PF03036.11 EOO03626.1 - 0.034 12.9 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Myosin_tail_1 PF01576.14 EOO03627.1 - 0.0026 15.5 12.4 0.0038 15.0 8.6 1.1 1 0 0 1 1 1 1 Myosin tail Borrelia_P83 PF05262.6 EOO03627.1 - 0.0049 15.1 7.9 0.0078 14.5 5.5 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein ERM PF00769.14 EOO03627.1 - 0.0056 16.2 9.8 0.0093 15.5 6.8 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2353 PF09789.4 EOO03627.1 - 0.0089 15.3 6.1 0.014 14.6 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF3323 PF11796.3 EOO03627.1 - 0.017 14.4 3.3 0.025 13.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) CCDC155 PF14662.1 EOO03627.1 - 0.022 14.3 13.0 0.045 13.3 9.0 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CALCOCO1 PF07888.6 EOO03627.1 - 0.094 10.9 6.3 0.13 10.5 4.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like WXG100 PF06013.7 EOO03627.1 - 0.13 12.2 4.0 0.45 10.5 1.7 2.5 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF4201 PF13870.1 EOO03627.1 - 0.19 11.1 12.2 0.41 10.0 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 EOO03627.1 - 0.21 11.1 6.3 0.35 10.4 4.4 1.3 1 0 0 1 1 1 0 IncA protein DUF2937 PF11157.3 EOO03627.1 - 0.21 10.8 3.8 0.37 10.1 2.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) FtsL PF04999.8 EOO03627.1 - 0.22 11.2 2.4 0.42 10.3 1.7 1.4 1 0 0 1 1 1 0 Cell division protein FtsL DUF4559 PF15112.1 EOO03627.1 - 0.23 10.6 6.9 0.32 10.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) AAA_13 PF13166.1 EOO03627.1 - 0.35 9.2 6.2 0.48 8.8 4.3 1.1 1 0 0 1 1 1 0 AAA domain Herpes_UL25 PF01499.11 EOO03627.1 - 0.36 9.0 4.0 0.18 10.0 1.2 1.5 1 1 0 1 1 1 0 Herpesvirus UL25 family APG6 PF04111.7 EOO03627.1 - 0.47 9.4 11.7 0.69 8.9 8.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EOO03627.1 - 0.49 9.5 18.3 0.076 12.1 9.1 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 EOO03627.1 - 0.49 9.0 8.4 0.65 8.6 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 EOO03627.1 - 0.66 7.7 2.3 0.83 7.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EOO03627.1 - 0.7 10.0 6.0 1.5 8.9 4.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LXG PF04740.7 EOO03627.1 - 0.7 9.6 6.3 1.5 8.5 2.7 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF2312 PF10073.4 EOO03627.1 - 1.2 8.4 5.3 0.12 11.7 0.3 1.8 2 1 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Laminin_II PF06009.7 EOO03627.1 - 2.2 8.0 5.6 3.3 7.4 3.9 1.3 1 0 0 1 1 1 0 Laminin Domain II Mnd1 PF03962.10 EOO03627.1 - 3.1 7.4 11.6 9 5.9 8.1 1.6 1 1 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 EOO03627.1 - 4 7.8 9.7 7 7.0 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GBP_C PF02841.9 EOO03627.1 - 4.9 6.2 11.5 7.8 5.5 8.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DivIVA PF05103.8 EOO03627.1 - 5.4 7.0 10.8 4.8 7.2 0.8 2.2 1 1 1 2 2 2 0 DivIVA protein TPR_MLP1_2 PF07926.7 EOO03627.1 - 5.4 6.7 13.9 28 4.4 9.6 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.8 EOO03627.1 - 6.6 5.6 6.3 8.8 5.2 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ald_Xan_dh_C2 PF02738.13 EOO03628.1 - 2.2e-191 636.9 0.0 2.9e-191 636.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EOO03628.1 - 1.5e-50 170.9 0.0 2.7e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EOO03628.1 - 2e-31 108.3 0.0 4.6e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EOO03628.1 - 7.6e-31 106.1 1.4 2e-30 104.7 0.1 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EOO03628.1 - 1.1e-28 98.9 0.0 2.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EOO03628.1 - 2e-08 33.8 1.8 3.4e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain APC_CDC26 PF10471.4 EOO03629.1 - 1.3 9.8 5.5 2.4 8.9 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Ras PF00071.17 EOO03630.1 - 1.8e-45 154.2 0.0 2.2e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO03630.1 - 2.8e-11 43.9 0.0 4.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO03630.1 - 4.3e-05 22.8 0.0 9.9e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Band_7 PF01145.20 EOO03631.1 - 1.3e-26 93.6 3.9 2e-26 92.9 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Snf7 PF03357.16 EOO03632.1 - 5.1e-22 78.0 5.7 5.1e-22 78.0 4.0 1.9 1 1 1 2 2 2 1 Snf7 Peptidase_C2 PF00648.16 EOO03633.1 - 2.1e-59 200.9 5.0 1.1e-39 136.2 0.6 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Dicty_REP PF05086.7 EOO03633.1 - 6.5 4.3 12.6 9.6 3.8 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 EOO03634.1 - 1.3e-28 97.8 3.6 3.6e-10 39.3 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 EOO03634.1 - 2.1e-08 33.9 2.2 2.1e-08 33.9 1.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EOO03634.1 - 7.2e-07 29.1 0.1 0.00061 19.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EOO03634.1 - 4.6e-06 25.6 0.0 2.8e-05 23.1 0.0 1.9 1 1 0 2 2 2 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EOO03634.1 - 0.0011 18.4 0.0 0.48 9.9 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EOO03634.1 - 0.0019 17.8 0.0 5.2 6.8 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Tachylectin PF14517.1 EOO03634.1 - 0.0099 15.2 0.0 0.028 13.7 0.0 1.8 1 1 0 1 1 1 1 Tachylectin DNA_pol_alpha_N PF12254.3 EOO03634.1 - 0.025 14.3 1.7 0.067 13.0 1.2 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 EOO03634.1 - 0.18 9.5 0.1 0.76 7.5 0.0 1.7 1 1 1 2 2 2 0 IKI3 family SPO22 PF08631.5 EOO03635.1 - 4.9e-43 147.1 2.1 1.8e-42 145.3 1.5 2.1 1 1 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like Sex_peptide PF08138.6 EOO03635.1 - 0.071 12.9 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Sex peptide (SP) family DUF2372 PF10178.4 EOO03635.1 - 0.13 12.4 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Hydantoinase_B PF02538.9 EOO03636.1 - 3.3e-76 256.6 6.0 8.3e-45 152.9 3.2 2.0 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase PEPcase_2 PF14010.1 EOO03636.1 - 0.18 10.1 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Cir_N PF10197.4 EOO03638.1 - 0.028 14.4 0.7 0.028 14.4 0.5 4.3 4 1 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR NUDIX PF00293.23 EOO03639.1 - 1e-08 34.9 0.7 1.4e-08 34.4 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain Ndc1_Nup PF09531.5 EOO03640.1 - 1.1e-74 252.0 0.0 1.2e-74 251.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-HIT PF04438.11 EOO03641.1 - 9.5e-10 37.9 8.3 1.4e-09 37.4 5.8 1.3 1 0 0 1 1 1 1 HIT zinc finger KxDL PF10241.4 EOO03643.1 - 6.2e-31 106.1 2.9 8.3e-31 105.7 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein ApoC-I PF04691.7 EOO03643.1 - 0.026 14.2 0.7 0.75 9.5 0.2 2.3 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) Syntaxin PF00804.20 EOO03643.1 - 0.3 11.2 2.5 0.52 10.5 0.1 1.9 1 1 0 1 1 1 0 Syntaxin DUF883 PF05957.8 EOO03643.1 - 4.1 7.8 6.7 9.9 6.6 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LSM14 PF12701.2 EOO03645.1 - 3.1e-34 116.6 0.0 5.8e-34 115.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EOO03645.1 - 3e-20 72.6 2.9 6.4e-20 71.6 2.0 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EOO03645.1 - 7.7e-06 25.7 0.1 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Aldedh PF00171.17 EOO03646.1 - 4.9e-139 463.6 0.0 6e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EOO03646.1 - 6.5e-07 28.4 0.0 0.00095 17.9 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) G_glu_transpept PF01019.16 EOO03648.1 - 6.3e-141 470.3 4.1 5.6e-95 318.7 0.3 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase adh_short PF00106.20 EOO03649.1 - 3.4e-16 59.6 0.2 4.9e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03649.1 - 6.3e-08 32.6 0.0 9.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03649.1 - 0.00023 20.9 0.1 0.00034 20.3 0.1 1.4 1 1 0 1 1 1 1 KR domain UNC45-central PF11701.3 EOO03650.1 - 2.1e-52 176.9 0.1 1.8e-48 164.1 0.0 4.1 3 1 0 4 4 4 2 Myosin-binding striated muscle assembly central Ras PF00071.17 EOO03651.1 - 1.6e-18 66.6 0.0 2.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO03651.1 - 1.6e-07 31.8 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO03651.1 - 0.0027 16.9 0.0 0.044 13.0 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Cir_N PF10197.4 EOO03651.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR G-alpha PF00503.15 EOO03651.1 - 0.068 11.8 0.3 0.09 11.4 0.2 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 EOO03651.1 - 0.069 12.6 0.2 0.35 10.4 0.1 2.0 1 1 1 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EOO03651.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2754 PF10953.3 EOO03652.1 - 0.41 10.7 3.6 0.58 10.2 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2754) PIG-H PF10181.4 EOO03653.1 - 1.6e-28 98.1 0.0 4.8e-28 96.5 0.0 1.7 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component DUF4006 PF13179.1 EOO03653.1 - 0.18 11.3 0.8 0.41 10.2 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Actin PF00022.14 EOO03654.1 - 1.1e-67 228.2 0.0 2.8e-67 226.8 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EOO03654.1 - 0.029 12.9 0.1 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Skp1_POZ PF03931.10 EOO03655.1 - 3.9e-11 42.8 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF1987 PF09345.5 EOO03656.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) MFS_1 PF07690.11 EOO03657.1 - 0.0008 18.2 0.7 0.0008 18.2 0.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YcxB PF14317.1 EOO03657.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein OB_NTP_bind PF07717.11 EOO03658.1 - 2.3e-26 91.8 0.0 6.6e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EOO03658.1 - 4.4e-23 81.2 0.0 8.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EOO03658.1 - 1.1e-10 41.2 0.0 2.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EOO03658.1 - 1.2e-07 31.9 0.1 3.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EOO03658.1 - 5e-07 29.3 0.6 1.3e-06 28.0 0.4 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EOO03658.1 - 0.0014 18.0 0.2 0.0042 16.5 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EOO03658.1 - 0.0027 17.5 0.1 0.57 9.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EOO03658.1 - 0.0064 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EOO03658.1 - 0.0084 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EOO03658.1 - 0.04 14.1 0.4 0.87 9.7 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 EOO03658.1 - 0.061 13.0 0.5 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_23 PF13476.1 EOO03658.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EOO03658.1 - 0.091 12.7 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Response_reg PF00072.19 EOO03658.1 - 0.13 12.2 0.6 0.81 9.7 0.1 2.4 3 0 0 3 3 3 0 Response regulator receiver domain AAA_29 PF13555.1 EOO03658.1 - 0.18 11.3 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Proteasome PF00227.21 EOO03659.1 - 6.8e-57 191.8 0.0 7e-33 113.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EOO03659.1 - 1.9e-11 43.0 0.3 4.2e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Sugar_tr PF00083.19 EOO03660.1 - 5.2e-93 312.0 23.4 6.2e-93 311.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03660.1 - 2.6e-24 85.6 49.9 4e-22 78.4 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.24 EOO03661.1 - 1.3e-56 190.4 0.0 1.9e-38 131.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO03661.1 - 1.3e-11 44.7 0.6 0.00025 21.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EOO03661.1 - 2.5e-08 34.1 0.0 0.0014 18.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 EOO03661.1 - 1.2e-07 31.7 0.0 0.00017 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EOO03661.1 - 1.4e-07 31.4 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EOO03661.1 - 1.7e-07 31.1 0.0 0.0087 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EOO03661.1 - 1.8e-07 30.2 0.0 0.011 14.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EOO03661.1 - 3.9e-07 30.9 0.0 0.01 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EOO03661.1 - 5.7e-07 29.4 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_5 PF07728.9 EOO03661.1 - 5.8e-07 29.3 0.0 0.00067 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EOO03661.1 - 2.1e-06 28.0 0.0 0.0088 16.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EOO03661.1 - 3.5e-06 26.6 0.2 0.011 15.4 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain RuvB_N PF05496.7 EOO03661.1 - 3.8e-06 26.1 0.1 0.038 13.0 0.1 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EOO03661.1 - 4.8e-06 26.6 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EOO03661.1 - 9.2e-06 24.9 0.2 0.0063 15.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EOO03661.1 - 3e-05 24.1 0.1 0.19 11.7 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 EOO03661.1 - 5.8e-05 22.6 0.0 0.36 10.2 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.7 EOO03661.1 - 7e-05 22.5 1.4 2.9 7.5 0.0 3.7 4 0 0 4 4 3 2 NACHT domain AAA_24 PF13479.1 EOO03661.1 - 0.00018 21.1 0.5 0.093 12.3 0.2 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EOO03661.1 - 0.00034 19.5 0.1 0.57 8.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain CDC48_2 PF02933.12 EOO03661.1 - 0.00052 19.6 0.1 0.0059 16.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 EOO03661.1 - 0.00064 19.1 1.0 0.3 10.4 0.0 3.4 3 1 1 4 4 4 1 AAA domain KaiC PF06745.8 EOO03661.1 - 0.00074 18.6 0.4 0.017 14.2 0.0 2.8 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.12 EOO03661.1 - 0.00083 18.8 0.1 0.069 12.5 0.0 2.6 3 0 0 3 3 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 EOO03661.1 - 0.001 19.3 0.3 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EOO03661.1 - 0.0013 18.4 0.3 19 4.8 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase Zeta_toxin PF06414.7 EOO03661.1 - 0.0041 16.2 0.0 0.37 9.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EOO03661.1 - 0.005 16.4 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EOO03661.1 - 0.005 16.8 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EOO03661.1 - 0.0052 16.0 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EOO03661.1 - 0.01 15.3 1.2 28 4.1 0.0 4.0 2 2 1 4 4 4 0 DEAD/DEAH box helicase AAA_30 PF13604.1 EOO03661.1 - 0.012 15.1 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 EOO03661.1 - 0.015 14.5 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 EOO03661.1 - 0.039 12.9 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EOO03661.1 - 0.062 13.1 0.8 7.6 6.3 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EOO03661.1 - 0.065 12.0 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 EOO03661.1 - 0.084 12.4 0.0 10 5.7 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EOO03661.1 - 0.093 12.3 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EOO03661.1 - 0.11 11.6 0.0 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 EOO03661.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EOO03661.1 - 0.14 12.0 0.1 13 5.6 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase Torsin PF06309.6 EOO03661.1 - 0.18 11.7 0.0 7.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Torsin Metallophos PF00149.23 EOO03662.1 - 4.3e-34 117.6 0.0 4.9e-29 101.1 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EOO03662.1 - 0.0052 16.6 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain NOSIC PF08060.8 EOO03662.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 NOSIC (NUC001) domain Sporozoite_P67 PF05642.6 EOO03662.1 - 0.31 8.8 3.6 0.44 8.3 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2416 PF10315.4 EOO03664.1 - 0.00071 19.8 1.0 0.0032 17.6 0.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4645 PF15488.1 EOO03664.1 - 0.13 11.3 0.2 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) zf-C2H2_4 PF13894.1 EOO03665.1 - 0.00053 20.1 4.1 0.39 11.1 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EOO03665.1 - 0.15 12.4 1.9 1.1 9.7 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1977 PF09320.6 EOO03666.1 - 1.3e-23 83.2 0.4 2.7e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EOO03666.1 - 1.8e-21 75.6 0.3 3e-21 74.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_34 PF05637.7 EOO03667.1 - 2.7e-71 239.8 0.0 3.4e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EOO03667.1 - 4.5e-05 22.8 0.0 0.015 14.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 OppC_N PF12911.2 EOO03667.1 - 0.17 11.3 0.7 0.46 9.8 0.5 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4203 PF13886.1 EOO03668.1 - 2.9e-31 108.5 9.1 3.8e-31 108.2 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Cnd3 PF12719.2 EOO03669.1 - 2.4e-94 315.6 0.6 2.4e-94 315.6 0.4 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EOO03669.1 - 2.7e-11 43.5 10.9 3.2e-06 27.3 0.7 4.7 3 2 0 3 3 3 3 HEAT repeats HEAT PF02985.17 EOO03669.1 - 2.7e-06 26.9 10.4 0.11 12.6 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat MMS19_N PF14500.1 EOO03669.1 - 0.0012 18.1 0.5 0.17 11.1 0.0 3.5 2 1 2 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 EOO03669.1 - 0.0073 16.3 0.5 0.8 9.8 0.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EOO03669.1 - 0.027 14.9 1.6 0.027 14.9 1.1 6.6 4 2 4 8 8 8 0 HEAT-like repeat RRM_1 PF00076.17 EOO03670.1 - 8.9e-57 188.6 0.1 4.1e-18 64.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03670.1 - 2e-42 142.9 0.1 6.9e-13 48.3 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03670.1 - 7.6e-19 67.3 0.2 2.9e-07 30.2 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HsbA PF12296.3 EOO03672.1 - 0.053 13.3 0.2 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Matrilin_ccoil PF10393.4 EOO03672.1 - 0.33 10.3 1.7 0.62 9.4 0.5 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CorA PF01544.13 EOO03673.1 - 2.5e-05 23.4 0.1 4.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.23 EOO03674.1 - 1.7e-70 237.5 0.0 2.1e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO03674.1 - 7.5e-17 62.0 0.0 1.7e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_Mu_Gp45 PF06890.7 EOO03674.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Pectate_lyase_3 PF12708.2 EOO03675.1 - 3.1e-82 276.0 23.4 3e-64 217.2 6.0 2.9 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EOO03675.1 - 2.2e-06 27.0 2.9 0.011 15.1 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase E1-E2_ATPase PF00122.15 EOO03676.1 - 2.2e-58 197.0 0.7 2.2e-58 197.0 0.5 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EOO03676.1 - 1.6e-43 148.3 7.8 1.6e-43 148.3 5.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EOO03676.1 - 5.2e-27 95.6 0.0 2.8e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO03676.1 - 7.4e-21 73.9 0.0 1.4e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EOO03676.1 - 1.3e-14 54.8 0.0 5.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO03676.1 - 8.5e-06 25.5 0.5 5.5e-05 22.8 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EOO03676.1 - 4.1e-05 22.9 0.3 0.00039 19.8 0.0 2.8 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus FAD_binding_4 PF01565.18 EOO03677.1 - 5.3e-24 84.2 6.1 1.9e-23 82.4 3.5 2.2 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EOO03677.1 - 0.00019 21.2 0.0 0.0008 19.2 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.9 EOO03677.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Methyltransf_23 PF13489.1 EOO03679.1 - 9.4e-10 38.4 0.0 2.1e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03679.1 - 0.0011 19.4 0.0 0.025 15.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03679.1 - 0.0046 17.4 0.0 0.32 11.4 0.0 3.0 1 1 1 2 2 2 1 Methyltransferase domain Surp PF01805.15 EOO03680.1 - 4.4e-15 55.0 0.0 8.2e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Surp module TAF4 PF05236.9 EOO03680.1 - 0.94 8.6 4.4 1.7 7.8 3.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DASH_Duo1 PF08651.5 EOO03681.1 - 8.8e-31 105.3 0.4 1.3e-30 104.7 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Cut8_N PF14482.1 EOO03683.1 - 2.9 7.9 5.7 2.1 8.3 0.5 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain zf-CHY PF05495.7 EOO03684.1 - 1.8e-17 63.2 25.7 4.8e-16 58.6 10.6 3.3 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 EOO03684.1 - 0.0025 16.8 0.3 0.0025 16.8 0.2 2.3 2 1 0 2 2 2 1 Mu-like prophage protein Com RWD PF05773.17 EOO03684.1 - 0.064 13.1 0.3 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 RWD domain ERM PF00769.14 EOO03684.1 - 0.74 9.3 10.4 0.65 9.4 3.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DZR PF12773.2 EOO03684.1 - 3.5 7.5 19.9 5.3 6.9 0.6 3.8 3 1 0 3 3 3 0 Double zinc ribbon FAD_binding_1 PF00667.15 EOO03685.1 - 2.2e-64 216.8 0.0 3.8e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EOO03685.1 - 2.8e-11 43.9 0.0 8.6e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EOO03685.1 - 2.3e-07 30.8 0.0 5.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Osmo_MPGsynth PF09488.5 EOO03686.1 - 3.1e-130 434.2 0.0 3.8e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glycos_transf_2 PF00535.21 EOO03686.1 - 5.6e-05 22.8 0.8 0.18 11.4 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EOO03686.1 - 0.00046 20.0 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Spp-24 PF07448.6 EOO03686.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) DUF3295 PF11702.3 EOO03687.1 - 6.7e-158 526.8 34.0 7.8e-158 526.5 23.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EOO03687.1 - 2.4e-11 42.9 1.8 8.1e-11 41.3 0.6 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DAO PF01266.19 EOO03690.1 - 9e-52 176.1 0.8 4.7e-51 173.7 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EOO03690.1 - 3.4e-09 36.6 0.7 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EOO03690.1 - 4.4e-07 29.0 0.2 0.00032 19.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EOO03690.1 - 4.4e-06 25.8 0.0 4.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EOO03690.1 - 2.9e-05 24.2 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EOO03690.1 - 3.3e-05 23.8 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EOO03690.1 - 0.00019 21.3 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EOO03690.1 - 0.0086 15.0 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 EOO03690.1 - 0.0096 14.8 0.1 0.77 8.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EOO03690.1 - 0.015 14.3 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EOO03690.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNARE PF05739.14 EOO03691.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 SNARE domain VHS PF00790.14 EOO03692.1 - 4.6e-26 91.1 0.0 9.1e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EOO03692.1 - 2.3e-10 40.3 0.8 5.3e-10 39.1 0.6 1.6 1 0 0 1 1 1 1 GAT domain 2OG-FeII_Oxy PF03171.15 EOO03693.1 - 9.8e-18 64.2 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EOO03694.1 - 9.2e-28 96.8 0.1 1.4e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NTP_transf_2 PF01909.18 EOO03694.1 - 0.035 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DHDPS PF00701.17 EOO03695.1 - 5.2e-39 133.5 0.0 7e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Usp PF00582.21 EOO03698.1 - 2.1e-22 79.8 5.9 3.1e-20 72.7 1.8 2.9 2 1 0 2 2 2 1 Universal stress protein family zf-C2H2_2 PF12756.2 EOO03699.1 - 6.7e-31 106.3 6.6 1.9e-29 101.7 0.7 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EOO03699.1 - 1.5e-06 28.2 4.6 5.3e-06 26.4 3.2 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EOO03699.1 - 0.0006 19.8 6.4 0.0006 19.8 4.5 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EOO03699.1 - 0.009 16.2 8.1 1.6 9.2 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC5 PF06221.8 EOO03699.1 - 0.26 11.0 2.8 23 4.8 0.0 3.3 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-C2H2 PF00096.21 EOO03699.1 - 2.7 8.5 13.6 1.6 9.1 0.7 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type TBP PF00352.16 EOO03700.1 - 3e-70 231.5 0.1 4.5e-35 118.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EOO03700.1 - 0.00024 21.0 0.0 0.86 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EOO03700.1 - 0.014 15.6 0.2 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) RTA1 PF04479.8 EOO03701.1 - 5.4e-36 124.1 7.3 6.3e-36 123.9 5.1 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1600 PF07667.6 EOO03701.1 - 0.087 12.9 0.3 0.087 12.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) Glyco_hydro_16 PF00722.16 EOO03703.1 - 6.3e-44 149.4 3.1 6.3e-44 149.4 2.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 LURAP PF14854.1 EOO03705.1 - 0.0038 16.9 2.4 0.0038 16.9 1.7 2.4 1 1 1 2 2 2 1 Leucine rich adaptor protein HECT PF00632.20 EOO03706.1 - 1.9e-71 240.8 0.0 2.5e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2838 PF10998.3 EOO03706.1 - 0.086 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) E1-E2_ATPase PF00122.15 EOO03707.1 - 2.4e-51 173.9 0.0 4.7e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EOO03707.1 - 9.6e-36 124.2 0.7 3.1e-35 122.5 0.5 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EOO03707.1 - 2.7e-17 62.6 3.9 3.8e-11 42.9 0.1 3.2 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EOO03707.1 - 1.1e-15 58.3 0.0 2.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO03707.1 - 1.2e-05 25.0 0.2 4.6e-05 23.1 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EOO03707.1 - 0.004 17.3 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3210 PF11489.3 EOO03708.1 - 1.7e-203 678.2 91.7 1.7e-203 678.2 63.6 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) NMO PF03060.10 EOO03709.1 - 4.4e-62 210.1 0.1 6.2e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EOO03709.1 - 9.5e-09 34.5 0.0 0.00023 20.1 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EOO03709.1 - 0.0042 15.9 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TTL PF03133.10 EOO03710.1 - 2.7e-58 197.2 0.0 4.7e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EOO03710.1 - 1e-21 77.1 0.0 1.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EOO03710.1 - 0.0059 15.4 0.0 0.038 12.8 0.0 2.2 3 0 0 3 3 3 1 YheC/D like ATP-grasp HSP70 PF00012.15 EOO03711.1 - 2.2e-270 897.7 15.3 2.5e-270 897.6 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EOO03711.1 - 5.7e-18 64.6 2.9 1e-16 60.4 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 EOO03711.1 - 0.0032 16.3 0.5 0.07 11.9 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EOO03711.1 - 0.011 14.8 5.6 0.017 14.2 0.2 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EOO03711.1 - 3.6 7.4 10.1 4.3 7.1 0.1 3.7 3 1 0 3 3 3 0 Cell division protein FtsA AAA_12 PF13087.1 EOO03712.1 - 6.7e-54 182.3 0.0 1.2e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EOO03712.1 - 1.5e-41 142.5 0.7 7.4e-20 71.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.6 EOO03712.1 - 2.9e-29 101.8 0.3 7.7e-29 100.4 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_30 PF13604.1 EOO03712.1 - 8.6e-13 48.3 0.0 2.1e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO03712.1 - 4.9e-11 42.2 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EOO03712.1 - 5.3e-08 32.9 0.2 1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EOO03712.1 - 2.5e-07 30.4 0.3 0.11 11.9 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EOO03712.1 - 2.8e-05 23.8 0.0 9.3e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EOO03712.1 - 3.4e-05 23.3 0.1 6.7e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EOO03712.1 - 0.00038 19.9 0.1 0.00068 19.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EOO03712.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 EOO03712.1 - 0.0024 17.3 0.1 0.0071 15.7 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EOO03712.1 - 0.0041 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EOO03712.1 - 0.0051 15.8 0.1 0.084 11.8 0.1 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.1 EOO03712.1 - 0.0063 15.9 0.0 0.041 13.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EOO03712.1 - 0.0076 16.7 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF2075 PF09848.4 EOO03712.1 - 0.0093 14.9 0.0 0.019 13.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 EOO03712.1 - 0.0099 14.9 0.1 0.022 13.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EOO03712.1 - 0.011 14.6 0.1 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 EOO03712.1 - 0.012 15.3 0.3 0.036 13.8 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 cobW PF02492.14 EOO03712.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EOO03712.1 - 0.025 14.7 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EOO03712.1 - 0.053 13.2 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EOO03712.1 - 0.065 12.7 1.0 0.14 11.5 0.0 2.0 3 0 0 3 3 2 0 FtsK/SpoIIIE family UvrD_C PF13361.1 EOO03712.1 - 0.065 12.6 1.0 12 5.2 0.0 3.3 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EOO03712.1 - 0.08 13.1 0.1 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EOO03712.1 - 0.11 12.3 0.4 0.25 11.1 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EOO03713.1 - 1.2e-70 237.6 0.0 1.7e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03713.1 - 3.6e-46 157.3 0.0 6e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EOO03713.1 - 8.5e-16 58.1 0.0 4.8e-15 55.7 0.0 2.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EOO03713.1 - 6.5e-08 31.8 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EOO03713.1 - 0.031 13.9 2.2 0.12 12.0 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EOO03713.1 - 0.082 11.9 0.2 0.58 9.1 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EOO03713.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain DLH PF01738.13 EOO03714.1 - 5.4e-08 32.3 0.1 6.4e-08 32.1 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Cg6151-P PF10233.4 EOO03715.1 - 1.3e-39 134.6 13.1 1.5e-39 134.4 9.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.4 EOO03715.1 - 0.19 10.2 4.7 0.22 10.0 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1459 PF07312.6 EOO03715.1 - 1.1 9.2 3.4 2.5 8.0 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) DUF1430 PF07242.6 EOO03715.1 - 1.5 8.9 8.4 0.57 10.2 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3040 PF11239.3 EOO03715.1 - 6.1 6.9 11.0 3.6 7.6 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) SR-25 PF10500.4 EOO03716.1 - 4.2 6.7 19.1 6.6 6.1 6.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NST1 PF13945.1 EOO03716.1 - 6.4 6.8 17.6 2.4 8.1 2.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF500 PF04366.7 EOO03717.1 - 4.3e-44 148.9 0.4 7.9e-44 148.1 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EOO03717.1 - 2.9e-14 52.1 0.2 1.2e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EOO03717.1 - 2.4e-12 46.1 0.0 5.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EOO03717.1 - 3.1e-12 45.8 0.0 5.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Aminotran_4 PF01063.14 EOO03718.1 - 7.4e-31 107.3 0.0 9.8e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 EOO03719.1 - 7e-28 97.3 0.0 1.6e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ARID PF01388.16 EOO03720.1 - 3.1e-16 58.9 0.0 8.6e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain KH_1 PF00013.24 EOO03721.1 - 8.2e-84 275.1 31.3 1.3e-12 47.1 0.3 12.8 14 1 0 14 14 14 10 KH domain KH_3 PF13014.1 EOO03721.1 - 2.4e-59 196.1 26.3 1.2e-09 37.6 0.0 12.0 13 0 0 13 13 13 8 KH domain KH_2 PF07650.12 EOO03721.1 - 5e-12 45.2 24.5 0.018 14.5 0.1 8.0 8 0 0 8 8 8 4 KH domain SLS PF14611.1 EOO03721.1 - 2.3e-10 40.2 11.5 0.033 13.6 0.0 6.9 5 2 1 6 6 6 5 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 EOO03721.1 - 0.00039 20.0 8.7 8.6 6.1 0.0 5.5 7 0 0 7 7 7 2 BMC domain KH_4 PF13083.1 EOO03721.1 - 0.00068 19.2 9.1 0.064 12.8 0.1 5.3 5 0 0 5 5 5 2 KH domain KH_5 PF13184.1 EOO03721.1 - 0.0042 16.8 9.7 16 5.3 0.0 6.2 6 0 0 6 6 6 1 NusA-like KH domain DUF1951 PF09188.5 EOO03721.1 - 0.082 12.8 0.4 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) zf-primase PF09329.6 EOO03722.1 - 3.5e-17 61.7 0.8 6.2e-17 60.9 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger TRI12 PF06609.8 EOO03723.1 - 0.0075 14.5 1.6 0.22 9.6 0.1 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EOO03723.1 - 0.022 13.5 1.7 0.092 11.4 0.3 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF2837 PF10997.3 EOO03723.1 - 0.073 12.2 3.0 0.043 12.9 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2837) TPR_MLP1_2 PF07926.7 EOO03724.1 - 4.1e-27 94.5 27.1 4.1e-27 94.5 18.8 18.5 5 4 12 17 17 17 7 TPR/MLP1/MLP2-like protein DUF869 PF05911.6 EOO03724.1 - 2.3e-05 22.8 22.9 2.3e-05 22.8 15.8 10.7 1 1 7 10 10 10 5 Plant protein of unknown function (DUF869) DUF904 PF06005.7 EOO03724.1 - 0.0069 16.6 6.4 0.0069 16.6 4.5 25.4 13 8 7 21 21 21 1 Protein of unknown function (DUF904) zf-C3HC PF07967.8 EOO03725.1 - 1.5e-43 147.8 0.3 2.4e-38 130.9 0.2 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EOO03725.1 - 2.1e-26 91.5 1.1 4.5e-25 87.3 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 EOO03725.1 - 0.0002 21.6 0.1 0.0047 17.3 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Imm33 PF15580.1 EOO03725.1 - 0.011 15.1 0.2 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 33 GTP_EFTU PF00009.22 EOO03726.1 - 9.5e-49 165.3 0.9 1.1e-48 165.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EOO03726.1 - 1.6e-19 69.8 0.4 1.6e-19 69.8 0.2 2.0 3 0 0 3 3 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EOO03726.1 - 2.6e-08 33.8 0.0 5.9e-07 29.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EOO03726.1 - 2.7e-07 30.5 0.1 7.7e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EOO03726.1 - 2.9e-07 30.5 0.1 3.7e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EOO03726.1 - 1.3e-05 25.6 1.0 0.00044 20.7 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EOO03726.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 EOO03726.1 - 0.0077 15.4 0.1 0.59 9.3 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EOO03726.1 - 0.057 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 EOO03726.1 - 0.067 12.4 0.0 1.3 8.2 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 EOO03726.1 - 0.14 11.3 2.1 5.2 6.2 0.1 2.7 2 1 1 3 3 3 0 ADP-ribosylation factor family Glyco_hydro_92 PF07971.7 EOO03727.1 - 1.1e-156 522.4 4.5 1.5e-156 522.0 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF2461 PF09365.5 EOO03727.1 - 3e-70 235.8 0.1 4.4e-70 235.3 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Nop14 PF04147.7 EOO03727.1 - 0.12 10.3 13.0 0.19 9.6 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EOO03727.1 - 0.36 10.3 13.9 0.64 9.5 9.7 1.3 1 0 0 1 1 1 0 PPP4R2 Trypan_PARP PF05887.6 EOO03727.1 - 6.4 6.6 7.9 12 5.7 5.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 EOO03727.1 - 8.4 5.5 13.6 17 4.5 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein adh_short PF00106.20 EOO03728.1 - 7.2e-31 107.3 1.4 9.5e-31 106.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03728.1 - 2.3e-27 96.3 0.2 2.9e-27 95.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03728.1 - 1.5e-11 44.2 0.2 2.2e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO03728.1 - 1.1e-05 25.0 0.1 4.4e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EOO03728.1 - 0.0005 19.7 0.3 0.0014 18.2 0.2 1.8 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 EOO03728.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EOO03728.1 - 0.072 11.7 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SelR PF01641.13 EOO03729.1 - 7.3e-50 167.8 0.0 1.1e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 SelR domain RNase_H2-Ydr279 PF09468.5 EOO03730.1 - 8.4e-92 307.6 2.8 1.1e-91 307.2 1.9 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Pkinase PF00069.20 EOO03731.1 - 3.7e-08 32.8 0.0 9.5e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO03731.1 - 2.1e-07 30.3 0.0 2.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EOO03732.1 - 6.3e-23 81.0 23.7 6.3e-23 81.0 16.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CLN3 PF02487.12 EOO03732.1 - 0.026 13.2 0.5 3.4 6.3 0.0 2.2 2 0 0 2 2 2 0 CLN3 protein MFS_1_like PF12832.2 EOO03732.1 - 0.054 13.2 2.0 0.68 9.7 0.2 2.6 2 0 0 2 2 2 0 MFS_1 like family Methyltransf_16 PF10294.4 EOO03733.1 - 8.1e-12 44.9 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EOO03733.1 - 0.00044 20.8 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EOO03733.1 - 0.0022 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EOO03733.1 - 0.0083 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G SpoIIIAH PF12685.2 EOO03733.1 - 0.019 14.4 0.5 0.035 13.6 0.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein MTS PF05175.9 EOO03733.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF1237 PF06824.6 EOO03734.1 - 1.1e-126 422.8 0.0 2.6e-89 299.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) Seipin PF06775.9 EOO03735.1 - 4.5e-55 186.2 0.4 6.1e-55 185.8 0.3 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PhyH PF05721.8 EOO03736.1 - 1.4e-09 38.3 0.1 4.9e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MIase PF02426.11 EOO03736.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Muconolactone delta-isomerase RRM_1 PF00076.17 EOO03737.1 - 1.2e-83 274.7 6.5 4.6e-23 80.6 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03737.1 - 4.8e-55 183.4 1.7 3e-16 59.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03737.1 - 7.8e-40 134.5 0.2 7.4e-10 38.5 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EOO03737.1 - 1e-30 105.2 3.5 2.2e-30 104.1 1.5 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EOO03737.1 - 0.0002 21.0 1.1 9.1 6.1 0.0 4.7 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EOO03737.1 - 0.00026 20.6 3.0 0.79 9.5 0.0 3.6 3 0 0 3 3 3 1 Limkain b1 CbiG_mid PF11761.3 EOO03737.1 - 0.01 16.0 5.6 4.8 7.4 0.0 4.2 4 0 0 4 4 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 EOO03737.1 - 0.046 13.2 1.7 7.6 6.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain TC1 PF15063.1 EOO03737.1 - 0.084 12.4 1.6 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Thyroid cancer protein 1 Nab6_mRNP_bdg PF10567.4 EOO03737.1 - 0.14 11.1 4.6 0.098 11.6 1.6 1.8 2 0 0 2 2 2 0 RNA-recognition motif RNase_H2-Ydr279 PF09468.5 EOO03737.1 - 0.23 10.6 10.1 0.45 9.6 7.0 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Glyco_hydro_61 PF03443.9 EOO03738.1 - 1.1e-41 143.1 0.0 1.2e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EOO03739.1 - 5.5e-15 54.9 14.2 6.6e-15 54.6 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03739.1 - 0.0013 17.4 5.4 0.0013 17.4 3.7 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EOO03739.1 - 0.15 10.4 14.4 0.91 7.8 10.1 1.9 1 1 1 2 2 2 0 MFS/sugar transport protein Romo1 PF10247.4 EOO03739.1 - 5.9 7.1 11.3 3 8.0 1.9 2.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DEAD PF00270.24 EOO03740.1 - 1.3e-42 145.1 0.1 6.3e-42 142.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO03740.1 - 4.3e-23 80.9 0.0 1.4e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EOO03740.1 - 1.6e-06 27.1 0.0 3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EOO03740.1 - 0.0014 18.5 0.7 0.0058 16.4 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EOO03740.1 - 0.082 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2325 PF10087.4 EOO03740.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) SIR2 PF02146.12 EOO03741.1 - 2.4e-61 206.5 0.0 6.5e-61 205.1 0.0 1.7 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.8 EOO03741.1 - 0.0016 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EOO03741.1 - 0.0092 15.7 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Ribosomal_S7 PF00177.16 EOO03742.1 - 4.4e-23 81.5 0.0 6.4e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NTF2 PF02136.15 EOO03744.1 - 7e-30 103.8 0.0 7.8e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EOO03744.1 - 0.0077 15.2 0.0 0.042 12.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) HECT PF00632.20 EOO03745.1 - 5.3e-83 278.7 0.0 1.1e-82 277.7 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EOO03745.1 - 0.0018 17.7 0.8 0.0041 16.6 0.5 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PSD5 PF07637.6 EOO03745.1 - 0.22 11.5 1.5 32 4.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) ETF_QO PF05187.8 EOO03746.1 - 1.5e-44 150.4 0.0 2.4e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 EOO03746.1 - 2.3e-08 33.9 0.0 7.1e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO03746.1 - 5.6e-08 32.0 0.0 0.00022 20.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO03746.1 - 2.2e-05 23.4 0.5 0.0027 16.6 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EOO03746.1 - 4.9e-05 22.5 0.0 0.0029 16.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EOO03746.1 - 7.7e-05 21.9 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO03746.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO03746.1 - 0.00018 20.1 0.3 0.00027 19.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EOO03746.1 - 0.00079 19.2 0.2 0.0024 17.6 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EOO03746.1 - 0.00095 18.3 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EOO03746.1 - 0.0023 16.6 0.0 0.17 10.5 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EOO03746.1 - 0.0032 17.5 0.0 0.0079 16.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EOO03746.1 - 0.0059 16.9 1.1 0.019 15.3 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 EOO03746.1 - 0.015 14.2 0.2 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EOO03746.1 - 0.048 14.0 0.0 4.1 7.8 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EOO03746.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FCH PF00611.18 EOO03747.1 - 1.8e-22 79.3 1.0 5.9e-22 77.6 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EOO03747.1 - 1.3e-13 50.1 0.0 2.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EOO03747.1 - 2.7e-11 42.8 0.0 6.5e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EOO03747.1 - 7.9e-11 41.2 0.0 5.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Syntaxin PF00804.20 EOO03747.1 - 0.61 10.2 5.5 3.3 7.9 3.8 2.2 1 1 0 1 1 1 0 Syntaxin Beta-lactamase PF00144.19 EOO03748.1 - 2.7e-42 144.9 2.9 3.3e-42 144.6 1.6 1.4 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 EOO03748.1 - 6.7e-07 29.0 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ESSS PF10183.4 EOO03749.1 - 5.8e-30 103.7 0.8 6.6e-30 103.6 0.6 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cpn60_TCP1 PF00118.19 EOO03750.1 - 3.3e-147 491.0 4.2 3.8e-147 490.8 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EOO03750.1 - 0.061 13.2 1.4 19 5.1 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Fip1 PF05182.8 EOO03751.1 - 6.5e-21 73.3 0.9 1.3e-20 72.4 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Abhydrolase_6 PF12697.2 EOO03752.1 - 2.8e-27 96.0 0.0 7.8e-27 94.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO03752.1 - 1.8e-17 63.6 0.0 2.5e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EOO03752.1 - 1.1e-11 44.6 0.0 2.2e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EOO03752.1 - 7.9e-06 25.1 0.0 2.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EOO03752.1 - 0.00029 20.3 0.0 0.00072 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EOO03752.1 - 0.00092 18.7 0.0 0.031 13.7 0.0 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EOO03752.1 - 0.00097 19.4 1.3 0.0063 16.7 0.1 2.7 2 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 EOO03752.1 - 0.0034 17.0 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EOO03752.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 EOO03752.1 - 0.033 13.7 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase DUF2305 PF10230.4 EOO03752.1 - 0.037 13.4 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EOO03752.1 - 0.087 12.3 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EOO03752.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PBP1_TM PF14812.1 EOO03752.1 - 2.1 8.6 7.2 3.3 8.0 3.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UDPGT PF00201.13 EOO03753.1 - 2.8e-05 22.8 0.0 4.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PAP_assoc PF03828.14 EOO03754.1 - 2.3e-16 59.4 0.4 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Cid1 family poly A polymerase Anp1 PF03452.9 EOO03755.1 - 8.7e-122 405.4 2.1 8e-121 402.3 0.0 2.0 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.5 EOO03755.1 - 0.038 13.7 3.5 0.063 13.0 2.4 1.3 1 0 0 1 1 1 0 Rad54 N terminal DUF573 PF04504.9 EOO03755.1 - 0.14 12.4 3.3 0.3 11.3 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Phi_1 PF04674.7 EOO03756.1 - 0.045 12.9 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Vps36_ESCRT-II PF11605.3 EOO03756.1 - 0.077 12.8 0.1 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Sugar_tr PF00083.19 EOO03757.1 - 7.9e-34 116.9 20.8 2.7e-33 115.2 14.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03757.1 - 5.8e-30 104.2 50.0 9.7e-27 93.5 21.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EOO03758.1 - 1.9e-33 115.8 0.0 3.1e-33 115.1 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF4278 PF14105.1 EOO03758.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) UMP1 PF05348.6 EOO03759.1 - 2.2e-23 82.6 0.0 2.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 BAGE PF08180.6 EOO03759.1 - 0.094 12.4 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 B melanoma antigen family Sugar_tr PF00083.19 EOO03760.1 - 1.4e-49 168.8 3.2 1.8e-49 168.5 2.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03760.1 - 2.1e-16 59.5 10.6 2.8e-16 59.1 7.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO03760.1 - 9.3e-05 20.8 1.4 0.00014 20.2 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aminotran_1_2 PF00155.16 EOO03762.1 - 2.2e-88 296.6 0.0 2.5e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PKD_channel PF08016.7 EOO03763.1 - 3.2e-06 25.8 17.2 3.7e-05 22.3 7.5 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.26 EOO03763.1 - 0.0041 16.3 21.4 0.28 10.4 14.8 2.3 1 1 0 1 1 1 1 Ion transport protein Seryl_tRNA_N PF02403.17 EOO03763.1 - 0.067 13.2 0.5 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EOO03763.1 - 0.14 11.6 0.2 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Sulfatase PF00884.18 EOO03765.1 - 2.2e-63 214.3 0.3 2.8e-63 213.9 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EOO03765.1 - 2.6e-09 36.9 1.2 0.00023 20.5 0.0 2.9 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EOO03765.1 - 0.041 12.3 0.0 0.084 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Hydrolase PF00702.21 EOO03766.1 - 5.2e-21 76.0 0.0 1.2e-19 71.5 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EOO03766.1 - 8.6e-21 74.0 0.0 2.5e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EOO03766.1 - 2.5e-20 73.4 0.0 5.5e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EOO03766.1 - 0.00021 21.1 0.0 0.00068 19.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EOO03766.1 - 0.0013 18.3 0.1 0.021 14.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EOO03768.1 - 8e-40 136.6 23.0 8e-40 136.6 16.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03768.1 - 6.5e-11 41.4 6.0 6.5e-11 41.4 4.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EOO03768.1 - 3.5e-07 28.8 1.1 5.3e-07 28.2 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adeno_E3 PF06040.6 EOO03769.1 - 0.073 13.0 0.2 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 protein Med15 PF09606.5 EOO03769.1 - 7 4.7 14.8 7.9 4.5 10.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-L28 PF09812.4 EOO03771.1 - 7.6e-08 32.3 3.6 1.1e-07 31.7 2.4 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Syntaxin-18_N PF10496.4 EOO03772.1 - 1e-12 47.6 0.8 3.8e-12 45.8 0.5 2.1 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EOO03772.1 - 0.0046 16.6 1.2 0.0046 16.6 0.9 2.7 3 0 0 3 3 3 1 SNARE domain HIT PF01230.18 EOO03773.1 - 1.4e-21 76.7 0.0 2.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EOO03773.1 - 0.00014 22.0 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding FAD_binding_3 PF01494.14 EOO03774.1 - 2.8e-12 46.3 0.0 1.2e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EOO03774.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EOO03774.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase Sulfotransfer_3 PF13469.1 EOO03776.1 - 0.33 11.8 3.8 0.58 11.0 2.6 1.6 1 1 0 1 1 1 0 Sulfotransferase family AA_permease PF00324.16 EOO03777.1 - 1.4e-128 429.3 48.7 1.6e-128 429.0 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO03777.1 - 2.3e-34 118.6 54.4 3e-34 118.2 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF383 PF04063.9 EOO03778.1 - 5.5e-69 231.5 0.1 2.9e-68 229.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EOO03778.1 - 2e-24 84.8 2.7 1.3e-23 82.3 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 EOO03778.1 - 0.016 13.4 0.0 0.096 10.9 0.1 2.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit MFS_1 PF07690.11 EOO03779.1 - 2.3e-27 95.6 0.1 2.3e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03779.1 - 3.9e-11 42.2 3.9 4.8e-11 41.9 2.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EOO03779.1 - 0.0001 20.8 1.0 0.00015 20.2 0.7 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein DUF791 PF05631.9 EOO03779.1 - 0.0022 16.7 0.2 0.0033 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) NIR_SIR PF01077.17 EOO03780.1 - 2.9e-53 179.4 0.0 3.7e-47 159.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EOO03780.1 - 5.2e-31 106.0 0.0 1.7e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EOO03780.1 - 5.7e-29 100.9 0.0 1.4e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EOO03780.1 - 6.1e-09 35.7 0.2 4.2e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Mito_carr PF00153.22 EOO03781.1 - 2.7e-57 190.4 1.2 4.6e-19 67.9 0.1 3.8 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EOO03783.1 - 4e-45 151.4 11.1 2.6e-18 65.5 0.2 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein MFS_1 PF07690.11 EOO03784.1 - 2.9e-32 111.7 18.2 3.5e-32 111.5 12.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HgmA PF04209.8 EOO03785.1 - 3.1e-34 118.1 0.1 3.6e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.21 EOO03786.1 - 1.8e-12 46.7 0.8 1.8e-12 46.7 0.5 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IpaD PF06511.6 EOO03786.1 - 0.0095 14.9 11.5 0.015 14.3 8.0 1.2 1 0 0 1 1 1 1 Invasion plasmid antigen IpaD DUF4366 PF14283.1 EOO03786.1 - 0.18 11.2 2.8 0.28 10.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDC27 PF09507.5 EOO03786.1 - 0.34 10.0 27.3 0.46 9.6 18.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_12 PF13424.1 EOO03787.1 - 2.2e-11 43.5 0.2 0.09 12.7 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 EOO03787.1 - 2.8e-10 40.3 3.7 0.051 13.2 0.0 5.9 3 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EOO03787.1 - 2.5e-09 36.9 15.0 2 9.2 0.0 10.2 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 EOO03787.1 - 1.2e-06 28.0 5.0 0.92 9.1 0.0 6.4 7 1 1 8 8 8 2 TPR repeat TPR_15 PF13429.1 EOO03787.1 - 1.6e-05 24.1 4.4 0.00087 18.4 0.7 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EOO03787.1 - 4e-05 23.3 7.0 1.1 9.0 0.1 6.0 6 0 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.1 EOO03787.1 - 0.00015 22.0 0.1 8.5 6.7 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EOO03787.1 - 0.00082 19.9 15.8 0.046 14.3 0.0 7.5 10 0 0 10 10 8 1 Tetratricopeptide repeat RPN7 PF10602.4 EOO03787.1 - 0.001 18.4 0.1 0.0038 16.6 0.1 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EOO03787.1 - 0.0035 17.0 6.3 1.4 8.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 EOO03787.1 - 0.065 13.5 0.1 1.1 9.7 0.0 3.3 3 0 0 3 3 1 0 Pentatricopeptide repeat domain TPR_2 PF07719.12 EOO03787.1 - 0.09 12.7 21.0 9.4 6.4 0.0 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EOO03787.1 - 0.22 10.3 15.7 1 8.1 0.1 6.1 2 2 4 6 6 6 0 NRDE-2, necessary for RNA interference Aldo_ket_red PF00248.16 EOO03788.1 - 1.6e-69 233.9 0.0 2e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF5 PF04855.7 EOO03789.1 - 1.7e-86 289.6 0.0 2.3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EOO03789.1 - 2.4e-05 23.5 1.8 5.8e-05 22.3 1.2 1.7 1 0 0 1 1 1 1 GATA zinc finger 2-oxoacid_dh PF00198.18 EOO03790.1 - 1.7e-76 256.4 0.1 2.3e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EOO03790.1 - 7.4e-19 67.1 0.9 1.5e-18 66.1 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EOO03790.1 - 5.2e-10 38.8 0.5 1.3e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain AATase PF07247.7 EOO03790.1 - 0.13 10.7 0.0 0.25 9.8 0.0 1.4 1 0 0 1 1 1 0 Alcohol acetyltransferase TFIIF_alpha PF05793.7 EOO03790.1 - 0.16 10.3 4.4 0.23 9.7 3.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) 4HBT PF03061.17 EOO03792.1 - 1.5e-12 47.4 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily DUF3608 PF12257.3 EOO03793.1 - 2.3e-65 220.2 0.0 8.3e-65 218.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) ABC_tran PF00005.22 EOO03794.1 - 6.5e-47 159.2 0.0 6.2e-24 84.8 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EOO03794.1 - 2.1e-17 64.0 0.1 0.0007 19.6 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EOO03794.1 - 4.2e-17 62.1 0.1 5.3e-06 25.8 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EOO03794.1 - 4e-10 39.0 0.0 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EOO03794.1 - 3.3e-09 37.3 6.5 0.00012 22.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EOO03794.1 - 3.3e-08 32.8 0.0 0.0003 19.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EOO03794.1 - 4.4e-08 33.9 0.0 0.0064 17.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EOO03794.1 - 8.5e-08 32.4 0.0 0.0021 18.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EOO03794.1 - 1.8e-07 31.1 0.0 0.0045 16.9 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EOO03794.1 - 5.8e-07 29.2 0.2 0.26 10.6 0.0 4.3 4 1 0 5 5 5 2 AAA-like domain AAA_15 PF13175.1 EOO03794.1 - 7.8e-07 28.4 3.5 0.12 11.3 0.0 4.8 4 1 1 5 5 5 1 AAA ATPase domain AAA_28 PF13521.1 EOO03794.1 - 1e-06 28.7 0.1 0.023 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EOO03794.1 - 1.7e-06 27.9 0.0 0.095 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EOO03794.1 - 4.8e-06 27.0 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EOO03794.1 - 6.5e-06 26.4 0.3 0.18 12.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EOO03794.1 - 9.7e-06 25.5 0.0 0.0019 18.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 EOO03794.1 - 1.2e-05 25.1 0.5 0.025 14.4 0.0 3.3 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EOO03794.1 - 1.5e-05 24.7 0.0 0.26 11.0 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EOO03794.1 - 1.6e-05 23.7 0.5 0.2 10.3 0.0 2.9 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 EOO03794.1 - 9.8e-05 22.4 0.0 0.79 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 EOO03794.1 - 0.00011 22.2 0.8 0.8 9.6 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.24 EOO03794.1 - 0.00012 22.2 0.0 0.44 10.7 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EOO03794.1 - 0.00012 21.5 0.0 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EOO03794.1 - 0.00017 21.3 0.0 0.08 12.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EOO03794.1 - 0.00039 20.3 0.0 1.8 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EOO03794.1 - 0.00043 20.0 0.0 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase AAA_13 PF13166.1 EOO03794.1 - 0.0011 17.6 4.1 1.4 7.2 0.0 3.9 4 1 0 4 4 4 2 AAA domain DUF87 PF01935.12 EOO03794.1 - 0.0015 18.4 1.1 0.83 9.4 0.0 3.8 4 0 0 4 4 3 1 Domain of unknown function DUF87 HEAT PF02985.17 EOO03794.1 - 0.0016 18.3 0.5 15 6.0 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat ATP-synt_ab PF00006.20 EOO03794.1 - 0.002 17.6 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EOO03794.1 - 0.0028 17.1 0.0 2.8 7.3 0.0 3.1 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EOO03794.1 - 0.0038 16.8 0.0 6.1 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain ParcG PF10274.4 EOO03794.1 - 0.0056 16.6 0.6 8.5 6.2 0.0 3.2 1 1 1 3 3 3 0 Parkin co-regulated protein Septin PF00735.13 EOO03794.1 - 0.0071 15.3 0.2 1.1 8.2 0.0 2.8 3 0 0 3 3 3 1 Septin MutS_V PF00488.16 EOO03794.1 - 0.0077 15.6 0.1 0.73 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V AAA_25 PF13481.1 EOO03794.1 - 0.0094 15.3 0.0 7.7 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain HEAT_2 PF13646.1 EOO03794.1 - 0.0098 16.1 7.9 0.51 10.6 2.4 3.9 1 1 3 4 4 4 1 HEAT repeats Cnd1 PF12717.2 EOO03794.1 - 0.011 15.5 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Rad17 PF03215.10 EOO03794.1 - 0.014 14.0 0.0 1.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 EOO03794.1 - 0.015 14.8 0.0 7.4 6.0 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EOO03794.1 - 0.017 14.5 0.2 4.1 6.8 0.0 3.2 3 1 0 3 3 3 0 FtsK/SpoIIIE family T2SE PF00437.15 EOO03794.1 - 0.023 13.6 0.1 2.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein PRK PF00485.13 EOO03794.1 - 0.033 13.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 EOO03794.1 - 0.04 12.6 0.1 1.5 7.4 0.0 2.6 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 EOO03794.1 - 0.046 12.5 0.1 0.45 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 EOO03794.1 - 0.05 12.7 0.0 3.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EOO03794.1 - 0.094 12.4 0.0 5.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain ADH_zinc_N PF00107.21 EOO03795.1 - 1.2e-06 28.0 0.2 6.8e-06 25.6 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HMG-CoA_red PF00368.13 EOO03795.1 - 0.00063 18.5 0.0 0.00093 17.9 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ADH_N PF08240.7 EOO03795.1 - 0.0011 18.6 0.0 0.0042 16.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.13 EOO03796.1 - 7e-29 100.4 0.0 9.9e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO03796.1 - 4.3e-09 36.1 10.7 6.6e-09 35.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.11 EOO03797.1 - 6e-45 153.1 0.0 1.2e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EOO03797.1 - 3e-35 121.6 0.0 5.2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EOO03797.1 - 2.3e-15 56.9 1.4 8.8e-15 55.0 1.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EOO03797.1 - 9.3e-11 40.9 0.3 3.7e-10 39.0 0.2 2.1 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.1 EOO03797.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 EOO03797.1 - 0.0065 15.9 0.6 0.027 13.9 0.4 2.1 1 1 0 1 1 1 1 HeH/LEM domain Toprim_3 PF13362.1 EOO03797.1 - 0.079 13.2 0.2 0.57 10.4 0.0 2.5 2 1 1 3 3 3 0 Toprim domain DUF2454 PF10521.4 EOO03798.1 - 4.9e-54 183.2 0.0 8.5e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EOO03798.1 - 8.6e-24 84.1 0.0 1.7e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EOO03798.1 - 8.5e-07 28.4 0.0 3.2e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EOO03798.1 - 0.00059 19.6 0.1 0.0023 17.7 0.1 1.9 1 1 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative HCR PF07111.7 EOO03798.1 - 0.18 9.7 0.0 0.26 9.2 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Ras PF00071.17 EOO03800.1 - 1.6e-49 167.4 0.0 1.8e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO03800.1 - 8.1e-16 58.5 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EOO03800.1 - 6.9e-07 28.6 0.0 9.9e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EOO03800.1 - 0.0071 15.5 0.0 0.0087 15.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EOO03800.1 - 0.031 13.4 0.0 0.057 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EOO03800.1 - 0.036 13.5 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EOO03800.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EOO03800.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 EOO03801.1 - 3.1e-38 131.4 9.5 1.1e-37 129.5 6.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1422 PF07226.6 EOO03801.1 - 0.024 14.3 0.2 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Sugar_tr PF00083.19 EOO03801.1 - 0.33 9.4 15.4 0.092 11.2 0.5 3.1 3 0 0 3 3 3 0 Sugar (and other) transporter DUF1673 PF07895.6 EOO03801.1 - 0.73 9.3 5.9 3.7 7.0 2.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) MFS_1 PF07690.11 EOO03802.1 - 2.6e-18 65.8 17.3 3.6e-18 65.4 12.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.14 EOO03802.1 - 0.023 14.7 0.9 0.043 13.8 0.6 1.4 1 0 0 1 1 1 0 Cellulose binding domain adh_short PF00106.20 EOO03803.1 - 5.1e-17 62.2 0.0 6.5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03803.1 - 8.8e-06 25.6 0.0 1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03803.1 - 0.00047 19.8 0.0 0.00062 19.4 0.0 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 EOO03804.1 - 6.6e-31 107.3 22.8 3.5e-23 81.9 8.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03804.1 - 1.6e-11 43.4 0.6 1.6e-11 43.4 0.4 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter NIR_SIR_ferr PF03460.12 EOO03804.1 - 0.16 11.6 0.3 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Aconitase_C PF00694.14 EOO03805.1 - 7.8e-22 77.7 0.1 3.5e-12 46.5 0.1 2.3 2 0 0 2 2 2 2 Aconitase C-terminal domain Aconitase PF00330.15 EOO03805.1 - 6.3e-18 64.5 0.2 8.6e-13 47.5 0.2 2.7 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) DUF3129 PF11327.3 EOO03806.1 - 7.3e-61 205.2 10.3 9.8e-61 204.7 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) I-set PF07679.11 EOO03806.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Zn_clus PF00172.13 EOO03807.1 - 6.6e-07 29.1 9.1 1.2e-06 28.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAPPC-Trs85 PF12739.2 EOO03808.1 - 8.1e-113 377.1 1.5 1.1e-112 376.6 1.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit BAR_2 PF10455.4 EOO03810.1 - 1.3e-59 201.4 0.2 1.8e-59 201.0 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EOO03810.1 - 1.2e-21 77.2 1.0 9.9e-21 74.2 0.7 1.9 1 1 0 1 1 1 1 BAR domain TauD PF02668.11 EOO03811.1 - 2.7e-40 138.6 0.0 3.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.4 EOO03811.1 - 0.018 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain NST1 PF13945.1 EOO03812.1 - 7.8e-58 195.6 7.0 7.8e-58 195.6 4.8 5.0 2 2 4 6 6 6 1 Salt tolerance down-regulator RNA_pol_3_Rpc31 PF11705.3 EOO03812.1 - 0.0064 16.4 7.0 0.0064 16.4 4.9 6.0 4 1 2 7 7 7 1 DNA-directed RNA polymerase III subunit Rpc31 cobW PF02492.14 EOO03813.1 - 6.2e-37 126.7 0.2 8.8e-37 126.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EOO03813.1 - 0.00027 20.4 0.8 0.0012 18.3 0.6 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CobW_C PF07683.9 EOO03813.1 - 0.00043 19.9 0.0 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.18 EOO03813.1 - 0.0066 16.3 0.8 0.021 14.7 0.5 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EOO03813.1 - 0.012 16.0 0.5 0.12 12.9 0.1 2.5 3 0 0 3 3 2 0 Miro-like protein AAA_19 PF13245.1 EOO03813.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EOO03813.1 - 0.018 13.7 1.9 1.4 7.6 0.1 2.7 3 0 0 3 3 3 0 ArgK protein AAA_18 PF13238.1 EOO03813.1 - 0.021 15.1 0.2 0.047 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EOO03813.1 - 0.021 14.9 0.3 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EOO03813.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 EOO03813.1 - 0.031 14.6 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EOO03813.1 - 0.044 13.3 0.5 0.21 11.0 0.4 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EOO03813.1 - 0.056 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 EOO03813.1 - 0.076 12.0 0.7 7.5 5.4 0.1 2.2 2 0 0 2 2 2 0 Septin DUF258 PF03193.11 EOO03813.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EOO03813.1 - 0.087 12.7 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EOO03813.1 - 0.092 12.7 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EOO03813.1 - 0.093 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EOO03813.1 - 0.14 12.4 0.2 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 ABC transporter PLA2_B PF01735.13 EOO03814.1 - 5.2e-26 90.8 0.0 1.1e-25 89.7 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PHO4 PF01384.15 EOO03816.1 - 6e-73 245.3 6.2 7.1e-73 245.0 4.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family ALMT PF11744.3 EOO03816.1 - 8.3 4.9 7.9 13 4.3 5.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AMP-binding PF00501.23 EOO03817.1 - 1.2e-23 83.1 0.0 1.6e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO03817.1 - 6.2e-13 49.4 0.1 1.4e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidohydro_4 PF13147.1 EOO03818.1 - 1.1e-19 71.5 11.7 6.8e-18 65.6 8.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EOO03818.1 - 7.6e-14 52.1 3.8 2e-13 50.6 2.6 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EOO03818.1 - 9.4e-12 44.8 8.7 6e-11 42.2 4.8 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EOO03818.1 - 4e-06 26.5 0.0 1.4e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase TrkA_N PF02254.13 EOO03818.1 - 0.024 14.6 0.7 0.13 12.2 0.2 2.3 2 1 0 2 2 2 0 TrkA-N domain SAP PF02037.22 EOO03818.1 - 0.15 11.5 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 SAP domain GST_N PF02798.15 EOO03819.1 - 1.2e-13 50.9 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EOO03819.1 - 1.6e-13 50.6 0.0 3.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EOO03819.1 - 2e-12 46.9 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EOO03819.1 - 1.2e-10 41.2 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EOO03819.1 - 3e-09 36.6 0.5 7.5e-09 35.3 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EOO03819.1 - 5e-07 30.1 0.0 7.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.16 EOO03820.1 - 1.4e-23 83.4 0.0 2.6e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EOO03820.1 - 0.13 10.7 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase ETC_C1_NDUFA4 PF04800.7 EOO03821.1 - 1e-38 131.2 0.3 1.4e-38 130.7 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region bact-PGI_C PF10432.4 EOO03821.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region CCDC144C PF14915.1 EOO03824.1 - 0.006 15.5 1.9 0.011 14.6 1.3 1.5 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region Pox_A6 PF04924.7 EOO03824.1 - 0.069 11.9 0.8 0.92 8.2 0.5 2.0 1 1 1 2 2 2 0 Poxvirus A6 protein Atg14 PF10186.4 EOO03824.1 - 0.091 11.6 1.1 0.13 11.2 0.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EOO03824.1 - 0.11 12.3 2.3 0.64 9.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COMP PF11598.3 EOO03824.1 - 0.16 12.0 1.8 23 5.1 0.2 3.2 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein MCM PF00493.18 EOO03825.1 - 2.8e-136 453.6 1.0 4.8e-136 452.9 0.7 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EOO03825.1 - 3.5e-20 72.6 0.0 2.2e-19 70.1 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EOO03825.1 - 2.6e-07 30.0 0.0 7.6e-07 28.4 0.0 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EOO03825.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EOO03825.1 - 0.0023 17.5 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EOO03825.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2360 PF10152.4 EOO03825.1 - 0.21 11.8 6.1 0.094 13.0 0.3 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4066 PF13278.1 EOO03826.1 - 1.1e-24 86.6 0.1 2e-24 85.7 0.1 1.3 2 0 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EOO03826.1 - 1.8e-13 50.1 0.0 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pribosyltran_N PF13793.1 EOO03827.1 - 2.3e-41 140.1 0.0 1.5e-39 134.3 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EOO03827.1 - 2.7e-36 125.0 0.0 3e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EOO03827.1 - 9.7e-07 28.5 0.0 0.00011 21.8 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EOO03827.1 - 0.04 13.1 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HK PF02110.10 EOO03827.1 - 0.088 11.9 0.2 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family ORC6 PF05460.8 EOO03827.1 - 0.2 10.7 5.8 0.27 10.2 3.7 1.4 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) PGAP1 PF07819.8 EOO03828.1 - 0.00075 19.1 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EOO03828.1 - 0.0044 16.7 0.0 0.018 14.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EOO03828.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EOO03828.1 - 0.016 15.0 0.1 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EOO03828.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DEAD PF00270.24 EOO03829.1 - 1.7e-46 157.7 0.0 9.3e-46 155.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EOO03829.1 - 4.7e-23 80.7 2.8 4.7e-23 80.7 1.9 2.1 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EOO03829.1 - 1.9e-21 75.6 0.1 1.2e-20 73.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIF_alpha PF05793.7 EOO03830.1 - 0.0023 16.3 9.4 0.0023 16.3 6.5 2.4 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp PF00026.18 EOO03831.1 - 1.3e-71 241.4 12.6 1.5e-71 241.2 8.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EOO03831.1 - 0.0001 22.2 0.0 0.0011 18.9 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EOO03831.1 - 0.00036 20.9 5.5 0.0027 18.1 1.1 2.9 2 1 0 2 2 2 1 Aspartyl protease RNase_H2_suC PF08615.6 EOO03832.1 - 2.8e-28 98.4 0.0 3.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3659 PF12396.3 EOO03833.1 - 2.7e-14 52.5 10.1 1.6e-11 43.7 2.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) CagX PF03524.10 EOO03833.1 - 0.081 12.1 1.7 2.6 7.2 0.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Aa_trans PF01490.13 EOO03834.1 - 9.5e-58 195.6 32.6 1.1e-57 195.4 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RPE65 PF03055.10 EOO03835.1 - 4.8e-36 124.3 0.0 6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Motile_Sperm PF00635.21 EOO03835.1 - 0.067 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Metallophos PF00149.23 EOO03836.1 - 8.5e-36 123.2 0.5 7.9e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase HBS1_N PF08938.5 EOO03837.1 - 0.0041 17.2 0.5 0.022 14.8 0.0 2.2 1 1 1 2 2 2 1 HBS1 N-terminus Cast PF10174.4 EOO03837.1 - 0.0088 14.1 1.5 0.0096 14.0 1.1 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 EOO03837.1 - 0.014 14.8 2.4 0.016 14.7 1.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF4164 PF13747.1 EOO03837.1 - 0.054 13.6 5.5 0.13 12.4 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) FemAB PF02388.11 EOO03837.1 - 0.069 11.8 0.1 0.088 11.4 0.1 1.0 1 0 0 1 1 1 0 FemAB family FH2 PF02181.18 EOO03837.1 - 0.074 11.9 0.2 0.087 11.6 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain CobN-Mg_chel PF02514.11 EOO03837.1 - 0.11 9.8 1.2 0.14 9.5 0.8 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Exonuc_VII_L PF02601.10 EOO03837.1 - 0.12 11.5 0.2 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSA PF07529.8 EOO03837.1 - 0.36 10.6 5.2 0.56 10.0 3.6 1.3 1 0 0 1 1 1 0 HSA PEP-utilisers_N PF05524.8 EOO03837.1 - 0.79 9.5 4.1 1.6 8.5 0.7 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal 2OG-FeII_Oxy PF03171.15 EOO03838.1 - 6.3e-16 58.4 0.0 8.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPRTase PF14681.1 EOO03840.1 - 5.9e-41 139.9 0.0 8.9e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EOO03840.1 - 2e-11 43.8 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EOO03840.1 - 1.5e-08 35.4 0.0 2.9e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EOO03840.1 - 1.2e-05 25.0 0.0 3.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EOO03840.1 - 4.5e-05 23.3 0.0 0.00018 21.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EOO03840.1 - 6.3e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EOO03840.1 - 0.00096 19.4 0.5 0.0022 18.2 0.3 1.6 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EOO03840.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EOO03840.1 - 0.0059 16.1 0.1 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EOO03840.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EOO03840.1 - 0.011 15.7 0.2 0.021 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EOO03840.1 - 0.013 15.3 1.0 0.032 14.0 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EOO03840.1 - 0.017 14.8 0.1 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EOO03840.1 - 0.018 13.8 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EOO03840.1 - 0.025 13.7 0.0 0.059 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 T2SE PF00437.15 EOO03840.1 - 0.051 12.4 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EOO03840.1 - 0.069 13.2 0.1 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EOO03840.1 - 0.11 11.9 0.2 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EOO03840.1 - 0.12 11.1 0.0 0.27 9.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 EOO03840.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EOO03840.1 - 0.14 12.1 0.2 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase CoaE PF01121.15 EOO03840.1 - 1.7 7.9 4.3 0.78 9.1 0.0 2.4 3 0 0 3 3 3 0 Dephospho-CoA kinase AAA_23 PF13476.1 EOO03840.1 - 4.5 7.5 4.9 1.9 8.7 0.4 1.9 1 1 1 2 2 2 0 AAA domain CUE PF02845.11 EOO03841.1 - 1.4e-06 27.6 0.0 2.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain Tmemb_cc2 PF10267.4 EOO03841.1 - 0.021 13.4 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Aldedh PF00171.17 EOO03841.1 - 0.039 12.2 2.2 0.057 11.7 1.5 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GDA1_CD39 PF01150.12 EOO03842.1 - 9.2e-110 367.1 0.0 1.2e-109 366.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.12 EOO03842.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 E2 (early) protein, C terminal LRR_8 PF13855.1 EOO03843.1 - 0.032 13.9 0.5 0.86 9.4 0.0 3.3 5 0 0 5 5 5 0 Leucine rich repeat Nucleoporin_FG PF13634.1 EOO03844.1 - 8.8e-17 61.3 44.1 8.8e-17 61.3 30.6 2.8 2 1 1 3 3 3 1 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 EOO03844.1 - 0.0051 16.6 0.4 0.66 9.7 0.0 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2580 PF10824.3 EOO03844.1 - 0.0095 16.2 0.1 0.037 14.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2580) Reo_sigmaC PF04582.7 EOO03844.1 - 0.017 14.3 0.8 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Pyr_redox_2 PF07992.9 EOO03845.1 - 2.6e-22 79.6 0.0 3.7e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO03845.1 - 5.2e-15 55.6 0.0 1.4e-10 41.4 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EOO03845.1 - 3.1e-07 29.2 0.3 7.7e-07 27.9 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EOO03845.1 - 1.2e-05 25.3 0.1 3.3e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EOO03845.1 - 1.4e-05 24.5 0.6 4.5e-05 22.9 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EOO03845.1 - 9e-05 21.6 1.5 0.00021 20.5 1.1 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 EOO03845.1 - 0.0013 18.8 0.1 0.99 9.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 EOO03845.1 - 0.048 13.2 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Kei1 PF08552.6 EOO03846.1 - 5e-45 153.4 10.0 9e-45 152.6 6.9 1.3 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.8 EOO03846.1 - 7.5 6.4 8.9 0.96 9.2 2.7 2.1 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CLTH PF10607.4 EOO03847.1 - 1.9e-33 115.1 0.0 3.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EOO03847.1 - 3.3e-08 32.9 0.0 6.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 LisH adh_short PF00106.20 EOO03848.1 - 2.6e-22 79.5 0.0 7.2e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO03848.1 - 7.7e-11 41.9 0.0 9.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO03848.1 - 6.6e-07 29.0 0.0 8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EOO03848.1 - 0.0018 17.3 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EOO03848.1 - 0.0019 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EOO03848.1 - 0.0082 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EOO03848.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EOO03848.1 - 0.012 15.6 0.3 0.031 14.2 0.2 2.0 1 1 0 1 1 1 0 NADH(P)-binding MOZ_SAS PF01853.13 EOO03849.1 - 3.1e-86 287.4 0.6 4.3e-86 286.9 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EOO03849.1 - 1.7e-18 66.0 0.0 4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2316 PF10078.4 EOO03849.1 - 0.041 13.8 0.5 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Acetyltransf_7 PF13508.1 EOO03849.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EOO03849.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.19 EOO03849.1 - 0.12 12.1 1.4 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain CDC27 PF09507.5 EOO03850.1 - 4.4e-66 223.9 22.3 7.8e-40 137.4 11.8 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 DUF1428 PF07237.6 EOO03850.1 - 0.031 14.1 0.4 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) Glyco_hydro_cc PF11790.3 EOO03852.1 - 1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.17 EOO03853.1 - 4.1e-25 87.2 0.6 2e-12 46.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03853.1 - 4.3e-18 65.0 0.0 3.5e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03853.1 - 1.3e-16 60.2 0.0 2.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EOO03853.1 - 0.099 12.4 0.6 0.24 11.2 0.2 1.9 1 1 1 2 2 2 0 RNA binding motif Whi5 PF08528.6 EOO03854.1 - 1e-05 25.0 0.0 1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Whi5 like Tombus_P33 PF08500.5 EOO03854.1 - 0.094 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Tombusvirus p33 NAD_binding_10 PF13460.1 EOO03855.1 - 9.6e-10 38.7 0.0 2.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO03855.1 - 1.2e-07 31.3 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EOO03855.1 - 2.2e-07 30.3 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EOO03855.1 - 1.3e-06 27.3 0.0 2.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EOO03855.1 - 0.0013 17.6 0.1 0.0035 16.2 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EOO03855.1 - 0.0054 16.6 0.2 0.16 11.8 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_20 PF12147.3 EOO03856.1 - 0.13 11.0 0.5 0.17 10.7 0.4 1.2 1 0 0 1 1 1 0 Putative methyltransferase NUDIX PF00293.23 EOO03857.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FSH1 PF03959.8 EOO03858.1 - 4.7e-22 78.4 0.0 7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LuxE PF04443.7 EOO03858.1 - 0.043 12.5 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE adh_short PF00106.20 EOO03860.1 - 8e-33 113.7 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03860.1 - 2e-27 96.5 0.0 3.3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03860.1 - 1.6e-17 63.7 0.0 2.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 KR domain fn3 PF00041.16 EOO03860.1 - 4.4e-09 36.3 2.6 1.1e-05 25.5 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain Epimerase PF01370.16 EOO03860.1 - 0.0073 15.7 0.0 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF924 PF06041.6 EOO03861.1 - 4.3e-14 52.6 0.0 2.1e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Catalase-rel PF06628.7 EOO03861.1 - 0.14 12.0 0.1 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive MFS_1 PF07690.11 EOO03862.1 - 3.8e-10 39.0 42.2 2.4e-09 36.4 27.3 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EOO03862.1 - 2e-07 29.6 11.2 4.1e-07 28.5 7.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GRAM PF02893.15 EOO03862.1 - 0.11 11.9 0.1 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 GRAM domain DUF4131 PF13567.1 EOO03862.1 - 2.6 7.4 15.8 0.089 12.1 2.2 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4131) Bystin PF05291.6 EOO03863.1 - 8.6e-123 409.0 0.0 1.2e-122 408.5 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF4139 PF13598.1 EOO03864.1 - 2.9e-61 207.5 8.4 2.7e-44 151.7 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EOO03864.1 - 9.5e-16 58.1 3.5 9.5e-16 58.1 2.4 4.0 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Tom22 PF04281.8 EOO03864.1 - 2.3 7.7 14.9 0.52 9.8 2.6 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 GAGA_bind PF06217.7 EOO03864.1 - 9.7 6.0 13.9 4.5 7.1 7.4 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family TPR_7 PF13176.1 EOO03866.1 - 0.5 10.2 1.8 5.8 6.9 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EOO03867.1 - 3.1e-43 147.5 0.0 4.7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EOO03867.1 - 6.8e-09 35.4 6.5 1.6e-08 34.2 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EOO03869.1 - 2.4e-08 33.4 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EOO03869.1 - 0.05 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase HycA_repressor PF11046.3 EOO03869.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Peptidase_S8 PF00082.17 EOO03870.1 - 4.1e-53 180.3 0.0 1.1e-52 178.9 0.0 1.8 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EOO03870.1 - 0.0092 16.3 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Rick_17kDa_Anti PF05433.10 EOO03871.1 - 2.4e-06 27.1 5.9 2.4e-06 27.1 4.1 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EOO03871.1 - 0.0066 15.9 4.6 0.0066 15.9 3.2 2.6 2 0 0 2 2 2 1 YMGG-like Gly-zipper TauE PF01925.14 EOO03871.1 - 0.019 14.4 3.8 0.027 13.9 2.7 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Gly-zipper_OmpA PF13436.1 EOO03871.1 - 0.18 11.4 13.5 0.15 11.7 3.1 2.6 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EOO03871.1 - 0.7 9.5 20.4 0.03 13.9 3.8 2.5 2 0 0 2 2 2 0 Glycine zipper DUF3659 PF12396.3 EOO03872.1 - 9.6e-104 339.0 49.2 1.5e-22 79.0 2.5 6.4 6 0 0 6 6 6 5 Protein of unknown function (DUF3659) LEA_4 PF02987.11 EOO03872.1 - 0.022 14.5 0.1 0.022 14.5 0.1 3.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein zf-Tim10_DDP PF02953.10 EOO03872.1 - 0.11 11.8 0.6 0.22 10.8 0.4 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger CDC73 PF05179.9 EOO03874.1 - 2.1e-45 155.1 0.1 6e-45 153.7 0.1 1.8 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family BBE PF08031.7 EOO03875.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.18 EOO03875.1 - 0.048 13.1 0.3 0.077 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Rad60-SLD_2 PF13881.1 EOO03876.1 - 1.2e-11 44.5 0.0 2.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EOO03876.1 - 3.4e-05 23.1 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EOO03876.1 - 0.00081 19.5 0.5 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain MAGE_N PF12440.3 EOO03876.1 - 0.91 9.8 12.7 0.98 9.7 8.0 1.7 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal Ras PF00071.17 EOO03877.1 - 1.4e-59 200.1 0.3 1.8e-59 199.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EOO03877.1 - 4.4e-21 75.5 0.2 8.1e-21 74.7 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EOO03877.1 - 7.4e-18 64.3 0.3 9.2e-18 64.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EOO03877.1 - 2e-08 33.9 0.0 8.9e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EOO03877.1 - 1.8e-06 27.2 0.3 2.3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EOO03877.1 - 8.2e-06 25.7 0.0 1.3e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EOO03877.1 - 9.5e-06 24.9 0.1 1.4e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EOO03877.1 - 0.0091 15.5 0.1 0.031 13.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EOO03877.1 - 0.024 14.4 0.2 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 EOO03877.1 - 0.034 14.0 0.0 2.1 8.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EOO03877.1 - 0.072 12.9 0.3 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EOO03877.1 - 0.082 13.0 0.0 1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EOO03877.1 - 0.09 12.4 0.3 4 7.1 0.0 2.6 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA-synt_1c PF00749.16 EOO03878.1 - 3.8e-98 328.0 0.0 5.5e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EOO03878.1 - 2.2e-33 115.3 0.0 4.3e-32 111.1 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribonucleas_3_3 PF14622.1 EOO03879.1 - 4.7e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EOO03879.1 - 0.0012 19.3 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EOO03879.1 - 0.0024 18.2 0.0 0.0072 16.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Oxidored_FMN PF00724.15 EOO03880.1 - 1.1e-86 290.9 0.0 1.2e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rib_5-P_isom_A PF06026.9 EOO03881.1 - 5e-42 143.1 0.0 2.2e-41 141.0 0.0 1.8 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Methyltransf_23 PF13489.1 EOO03882.1 - 4.2e-19 68.8 0.0 6.7e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO03882.1 - 1.2e-11 45.1 0.0 1.1e-10 42.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO03882.1 - 1.4e-11 44.2 0.0 2.4e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO03882.1 - 6.3e-09 36.2 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO03882.1 - 6.3e-08 32.9 0.0 3.5e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO03882.1 - 0.00017 21.8 0.0 0.00038 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EOO03882.1 - 0.00081 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EOO03882.1 - 0.0011 18.3 0.0 0.0033 16.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EOO03882.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EOO03882.1 - 0.0025 16.8 0.0 0.0068 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EOO03882.1 - 0.0027 17.7 0.1 0.0098 15.8 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EOO03882.1 - 0.0056 15.7 0.1 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EOO03882.1 - 0.0074 15.4 0.0 0.078 12.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EOO03882.1 - 0.025 13.7 0.2 0.51 9.4 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_16 PF10294.4 EOO03882.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase LtrA PF06772.6 EOO03883.1 - 6.5e-12 45.0 11.6 6.5e-12 45.0 8.1 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF2157 PF09925.4 EOO03883.1 - 2.9 7.4 18.2 0.98 9.0 2.8 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) NOT2_3_5 PF04153.13 EOO03884.1 - 1.9e-33 115.1 0.6 2.9e-33 114.5 0.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pro-kuma_activ PF09286.6 EOO03885.1 - 4.6e-30 104.5 0.1 1.1e-29 103.2 0.1 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EOO03885.1 - 0.00013 21.2 0.0 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 Subtilase family zf-C3HC4_3 PF13920.1 EOO03886.1 - 5.1e-08 32.4 12.7 8.7e-08 31.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 EOO03886.1 - 2.4 8.4 9.4 5.1 7.3 6.5 1.5 1 0 0 1 1 1 0 FAM24 family zf-C3HC4_2 PF13923.1 EOO03886.1 - 3.9 7.5 16.2 8 6.5 11.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pentapeptide_2 PF01469.13 EOO03887.1 - 0.00014 21.3 3.7 0.00014 21.3 2.6 3.6 3 0 0 3 3 3 1 Pentapeptide repeats (8 copies) DUF775 PF05603.7 EOO03888.1 - 7.1e-53 179.1 0.0 8.3e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) zf-C2HC5 PF06221.8 EOO03889.1 - 5.9e-22 77.1 5.7 9.5e-22 76.5 4.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF605 PF04652.11 EOO03889.1 - 2.9 7.1 12.6 4.7 6.4 8.7 1.3 1 0 0 1 1 1 0 Vta1 like Na_Ca_ex PF01699.19 EOO03890.1 - 2.2e-46 156.9 28.3 3.8e-23 81.6 8.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RR_TM4-6 PF06459.7 EOO03890.1 - 0.12 12.2 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3433 PF11915.3 EOO03891.1 - 1.2e-14 54.2 2.7 2.5e-14 53.2 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Cation_efflux PF01545.16 EOO03892.1 - 2.5e-61 207.2 1.7 3e-61 206.9 1.2 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 EOO03892.1 - 0.014 14.3 0.8 0.014 14.3 0.5 2.5 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component Ribosomal_60s PF00428.14 EOO03892.1 - 0.45 10.9 9.3 0.86 10.0 6.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macro PF01661.16 EOO03893.1 - 8.7e-39 132.0 0.3 1.3e-38 131.5 0.2 1.3 1 0 0 1 1 1 1 Macro domain U3snoRNP10 PF12397.3 EOO03893.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 RGS PF00615.14 EOO03894.1 - 4e-37 126.9 0.1 1.6e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EOO03894.1 - 1.2e-25 88.9 0.1 4.9e-21 74.2 0.0 3.3 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DEAD PF00270.24 EOO03895.1 - 9.3e-41 139.1 0.0 1.9e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO03895.1 - 1.5e-20 72.7 0.1 3.9e-20 71.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF336 PF03928.9 EOO03895.1 - 0.06 13.1 0.2 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF336) ResIII PF04851.10 EOO03895.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ketoacyl-synt_C PF02801.17 EOO03896.1 - 7.3e-38 129.0 0.1 1.3e-37 128.3 0.0 1.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EOO03896.1 - 0.00046 19.7 0.3 0.0017 17.8 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain IFN-gamma PF00714.12 EOO03897.1 - 0.0071 16.1 2.4 0.011 15.5 0.9 2.0 1 1 0 1 1 1 1 Interferon gamma RNA_pol_3_Rpc31 PF11705.3 EOO03898.1 - 6.8e-28 98.1 10.7 9.7e-28 97.6 7.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.7 EOO03898.1 - 6.7 5.7 12.7 9.1 5.3 8.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT adh_short PF00106.20 EOO03899.1 - 1.3e-32 112.9 0.0 2.3e-32 112.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO03899.1 - 1.7e-14 54.2 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO03899.1 - 5.5e-13 48.9 0.0 8.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EOO03899.1 - 0.032 13.1 0.1 0.062 12.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EOO03899.1 - 0.037 13.8 0.1 0.094 12.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Syja_N PF02383.13 EOO03900.1 - 1.8e-92 309.5 0.0 3.6e-92 308.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain WYL PF13280.1 EOO03900.1 - 0.0037 17.1 0.3 0.019 14.8 0.0 2.2 3 0 0 3 3 3 1 WYL domain TPP_enzyme_N PF02776.13 EOO03901.1 - 5.4e-58 195.2 0.1 8.5e-57 191.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EOO03901.1 - 2.5e-50 169.9 0.1 4.5e-49 165.9 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EOO03901.1 - 3.7e-36 123.8 0.8 1.5e-35 121.9 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain IL13 PF03487.8 EOO03901.1 - 0.094 12.4 0.3 0.39 10.4 0.2 2.1 1 0 0 1 1 1 0 Interleukin-13 MFS_1 PF07690.11 EOO03902.1 - 2.7e-29 101.9 53.2 2.1e-28 99.0 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EOO03902.1 - 8.4e-05 22.2 1.1 0.2 11.5 0.0 3.1 2 0 0 2 2 2 2 MFS_1 like family DUF1938 PF09153.5 EOO03902.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Spo7 PF03907.8 EOO03903.1 - 1.3e-68 230.7 0.0 1.7e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein UQ_con PF00179.21 EOO03904.1 - 3.6e-39 133.3 0.0 4.4e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EOO03904.1 - 0.00014 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EOO03904.1 - 0.031 14.1 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EOO03904.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_7 PF00840.15 EOO03905.1 - 1.2e-97 327.1 6.2 1.3e-97 326.9 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 TAF8_C PF10406.4 EOO03905.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CsbD PF05532.7 EOO03906.1 - 5e-06 26.0 7.1 0.00035 20.1 0.6 2.3 2 0 0 2 2 2 2 CsbD-like DUF1206 PF06724.6 EOO03906.1 - 0.48 10.2 2.2 8.6 6.1 0.2 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) CN_hydrolase PF00795.17 EOO03907.1 - 2.7e-21 75.7 0.0 4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.13 EOO03908.1 - 6.9e-122 405.8 0.4 6.9e-122 405.8 0.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EOO03908.1 - 2.7e-07 30.5 0.0 6.5e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EOO03908.1 - 3.5e-05 23.3 2.1 0.00056 19.3 0.0 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EOO03908.1 - 5.8e-05 22.3 0.5 0.0005 19.2 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EOO03908.1 - 0.00027 21.2 4.4 0.017 15.3 0.0 2.9 2 1 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EOO03908.1 - 0.0008 18.9 2.9 0.0037 16.7 1.8 2.2 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 EOO03908.1 - 0.0012 18.0 2.2 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EOO03908.1 - 0.0015 18.5 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EOO03908.1 - 0.0022 18.1 0.1 0.021 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EOO03908.1 - 0.0022 18.4 0.3 0.0098 16.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EOO03908.1 - 0.0053 16.2 1.8 0.02 14.3 0.0 2.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family Ras PF00071.17 EOO03908.1 - 0.0064 15.8 0.1 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.1 EOO03908.1 - 0.0069 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EOO03908.1 - 0.028 14.2 7.7 0.5 10.1 0.0 3.5 3 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EOO03908.1 - 0.037 14.2 1.0 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 EOO03908.1 - 0.04 13.4 0.1 8.9 5.7 0.0 3.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EOO03908.1 - 0.074 12.6 0.8 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EOO03908.1 - 0.079 11.6 10.7 0.42 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EOO03908.1 - 0.082 12.6 2.2 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EOO03908.1 - 0.099 12.0 0.0 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 EOO03908.1 - 0.23 11.2 2.1 0.34 10.7 0.5 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Phage_GPO PF05929.6 EOO03908.1 - 1.5 7.9 6.5 2.5 7.3 4.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.14 EOO03908.1 - 5.2 4.7 11.1 7.8 4.2 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 EOO03908.1 - 7.6 6.2 7.6 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Exonuc_VII_L PF02601.10 EOO03908.1 - 9.1 5.3 12.1 8.8 5.4 7.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Sugar_tr PF00083.19 EOO03909.1 - 2e-42 145.3 18.8 2.6e-42 144.9 13.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03909.1 - 3.1e-17 62.3 25.1 4.8e-17 61.6 17.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.6 EOO03909.1 - 0.2 11.6 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase muHD PF10291.4 EOO03910.1 - 0.018 14.2 0.0 0.075 12.2 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Nuc_deoxyrib_tr PF05014.10 EOO03910.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase NAD_binding_10 PF13460.1 EOO03911.1 - 9.3e-13 48.5 0.1 1.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EOO03911.1 - 2.1e-11 43.5 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EOO03911.1 - 2.7e-07 29.9 0.0 3.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EOO03911.1 - 2e-05 24.1 0.1 3.7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EOO03911.1 - 0.0037 17.2 0.2 0.0075 16.2 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EOO03911.1 - 0.0089 14.7 0.1 0.025 13.2 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EOO03911.1 - 0.013 15.8 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EOO03911.1 - 0.015 15.6 1.8 0.032 14.6 1.2 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EOO03911.1 - 0.026 15.0 0.1 0.054 14.0 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UPF0146 PF03686.8 EOO03911.1 - 0.048 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Pyr_redox PF00070.22 EOO03911.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EOO03911.1 - 0.089 11.9 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EOO03911.1 - 0.1 12.4 0.2 0.25 11.1 0.2 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EOO03911.1 - 0.12 11.9 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 EOO03912.1 - 1.3e-36 126.0 30.9 1.6e-32 112.5 11.9 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO03912.1 - 8.8e-14 50.9 27.2 1.7e-13 49.9 8.5 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EOO03912.1 - 2.2e-07 29.4 7.3 2.2e-07 29.4 5.0 2.2 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EOO03912.1 - 0.097 11.3 9.0 1.9 7.0 6.3 2.6 1 1 0 1 1 1 0 BT1 family DUF4131 PF13567.1 EOO03912.1 - 6.2 6.1 12.7 14 5.0 0.4 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4131) RabGAP-TBC PF00566.13 EOO03913.1 - 7.5e-35 120.3 0.0 2.5e-33 115.3 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain OPT PF03169.10 EOO03914.1 - 3.3e-71 240.5 15.3 3.9e-71 240.3 10.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NfeD PF01957.13 EOO03914.1 - 1.8 8.6 14.5 4.1 7.5 1.9 3.2 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2207 PF09972.4 EOO03914.1 - 2.7 6.4 6.3 0.32 9.5 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 EOO03915.1 - 2.4e-32 112.0 27.8 3.6e-32 111.4 19.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FliW PF02623.10 EOO03916.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 FliW protein MFS_1 PF07690.11 EOO03920.1 - 1.1e-38 132.9 23.0 6.9e-38 130.2 16.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.1 EOO03920.1 - 0.93 9.6 6.4 3.5 7.7 0.3 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) DUF1049 PF06305.6 EOO03920.1 - 1.9 8.0 5.1 21 4.6 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Sec7 PF01369.15 EOO03921.1 - 6e-64 215.2 2.4 8.9e-64 214.6 0.2 2.4 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EOO03921.1 - 2.7e-52 176.5 1.3 2.7e-52 176.5 0.9 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EOO03921.1 - 4.8e-32 109.3 0.2 4.8e-32 109.3 0.1 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sugar_tr PF00083.19 EOO03922.1 - 7.3e-121 403.8 21.9 1.4e-120 402.9 15.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03922.1 - 4e-22 78.4 53.5 1.1e-12 47.3 20.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 EOO03922.1 - 0.096 12.6 0.3 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Cep57_CLD_2 PF14197.1 EOO03924.1 - 0.07 13.0 18.2 1 9.3 0.9 4.3 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 CDC37_N PF03234.9 EOO03924.1 - 0.76 10.0 14.4 0.064 13.5 6.0 2.1 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding ING PF12998.2 EOO03924.1 - 2.7 8.3 9.7 0.87 9.8 3.5 2.6 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding WLM PF08325.5 EOO03925.1 - 6.5e-05 22.8 1.8 9e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 WLM domain DUF221 PF02714.10 EOO03927.1 - 3.1e-105 351.6 22.2 3.1e-105 351.6 15.4 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EOO03927.1 - 2.4e-17 62.5 0.0 8.5e-17 60.8 0.0 2.0 1 0 0 1 1 1 1 Phosphate metabolism protein RSN1_TM PF13967.1 EOO03927.1 - 6.6e-10 38.7 0.1 6.6e-10 38.7 0.1 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EOO03927.1 - 1.8e-08 34.7 12.9 0.0015 19.0 6.5 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) RNase_H2-Ydr279 PF09468.5 EOO03927.1 - 0.056 12.6 4.0 0.1 11.8 2.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Bap31 PF05529.7 EOO03927.1 - 8.3 5.8 13.9 0.32 10.4 0.8 2.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1077 PF06417.7 EOO03928.1 - 9.3e-48 160.7 4.0 1.2e-47 160.3 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Snf7 PF03357.16 EOO03929.1 - 3.2e-20 72.2 11.1 3.2e-20 72.2 7.7 2.1 1 1 1 2 2 2 1 Snf7 Phage_int_SAM_1 PF02899.12 EOO03929.1 - 0.013 15.6 1.2 0.08 13.1 0.8 2.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Radical_SAM PF04055.16 EOO03929.1 - 0.11 12.6 0.7 1.7 8.7 0.1 2.3 1 1 1 2 2 2 0 Radical SAM superfamily DUF4481 PF14800.1 EOO03929.1 - 0.23 10.3 1.1 0.47 9.3 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) THOC7 PF05615.8 EOO03929.1 - 7.8 6.7 19.3 3.9 7.7 1.6 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1014 PF06244.7 EOO03930.1 - 9e-23 80.7 12.5 3.5e-22 78.8 8.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) RNase_PH PF01138.16 EOO03931.1 - 9.5e-11 42.1 0.3 7.5e-10 39.2 0.0 2.2 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 S4 PF01479.20 EOO03932.1 - 4.8e-15 54.7 0.0 1e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EOO03932.1 - 0.0011 18.5 0.1 0.0091 15.5 0.0 2.2 2 0 0 2 2 2 1 S4 domain EcKinase PF02958.15 EOO03933.1 - 8e-21 74.4 0.0 1.3e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EOO03933.1 - 1.4e-11 44.5 0.3 3.2e-11 43.4 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EOO03933.1 - 4.4e-08 32.1 0.0 1.9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Kelch_5 PF13854.1 EOO03934.1 - 3.2e-14 52.5 10.4 3.2e-12 46.1 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EOO03934.1 - 6.4e-06 26.1 1.0 0.017 15.2 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EOO03934.1 - 0.00013 21.3 5.1 0.097 12.2 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EOO03934.1 - 0.00093 19.2 3.0 9 6.6 0.0 5.2 4 1 0 4 4 4 1 Kelch motif TauD PF02668.11 EOO03935.1 - 5.8e-51 173.6 0.1 6.9e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family End3 PF12761.2 EOO03936.1 - 4.1e-74 248.4 5.4 5.5e-74 248.0 3.7 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EOO03936.1 - 4e-48 161.4 0.0 2e-47 159.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EOO03936.1 - 8e-07 27.9 0.2 1.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EOO03936.1 - 3.8e-06 26.4 0.1 8.6e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EOO03936.1 - 4.4e-05 23.5 0.0 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EOO03936.1 - 0.00074 19.1 0.2 0.0027 17.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EOO03936.1 - 0.004 16.4 0.1 0.013 14.7 0.1 2.0 1 0 0 1 1 1 1 EF hand DUF2408 PF10303.4 EOO03936.1 - 0.022 14.8 1.8 0.092 12.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.7 EOO03936.1 - 0.1 12.8 1.6 26 5.1 0.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EOO03936.1 - 0.16 11.8 5.0 9.7 6.1 0.4 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad3 PF08656.5 EOO03936.1 - 0.32 10.7 6.9 1.5 8.5 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 COG2 PF06148.6 EOO03936.1 - 1.4 8.8 6.0 0.74 9.6 0.5 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 EOO03936.1 - 1.5 8.5 12.1 11 5.7 0.5 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EOO03936.1 - 3.8 7.5 10.7 2.6 8.0 2.4 2.6 1 1 0 2 2 2 0 FlxA-like protein EMP24_GP25L PF01105.19 EOO03936.1 - 3.8 7.1 5.4 5.9 6.5 0.1 2.6 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD TBPIP PF07106.8 EOO03936.1 - 7.1 6.1 11.9 20 4.6 6.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) XAP5 PF04921.9 EOO03937.1 - 8.5e-83 277.5 0.1 2e-82 276.3 0.0 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator Methyltransf_10 PF05971.7 EOO03937.1 - 7.7e-66 222.2 0.0 1.1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EOO03937.1 - 2.2e-05 24.4 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EOO03937.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EOO03937.1 - 0.014 16.0 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 EOO03938.1 - 5.9e-73 245.9 25.5 7.2e-73 245.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO03938.1 - 1.7e-22 79.6 29.4 8.5e-21 74.0 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2613 PF11021.3 EOO03938.1 - 0.077 12.7 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) FNIP_N PF14636.1 EOO03939.1 - 5.8e-22 78.5 0.1 5.8e-22 78.5 0.0 4.5 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 EOO03939.1 - 0.018 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus TRP PF06011.7 EOO03940.1 - 0.042 12.4 0.1 0.045 12.3 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel TMCO5 PF14992.1 EOO03940.1 - 0.13 11.3 6.1 0.15 11.1 4.2 1.1 1 0 0 1 1 1 0 TMCO5 family Arm PF00514.18 EOO03941.1 - 0.018 14.8 1.2 25 4.9 0.2 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EOO03941.1 - 0.32 11.1 3.2 10 6.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DUF1996 PF09362.5 EOO03943.1 - 3.8e-77 259.1 2.0 5.3e-77 258.6 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DAO PF01266.19 EOO03944.1 - 5.9e-11 41.8 0.0 6.9e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EOO03944.1 - 0.027 13.3 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amidohydro_1 PF01979.15 EOO03945.1 - 3.2e-39 135.4 0.1 4.3e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EOO03945.1 - 1.1e-12 48.5 0.0 8.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EOO03945.1 - 2.8e-11 43.0 0.0 8.2e-11 41.5 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EOO03945.1 - 5.1e-07 29.2 0.0 0.00083 18.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family SIR2 PF02146.12 EOO03946.1 - 1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MatE PF01554.13 EOO03947.1 - 6.3e-55 185.2 27.7 5.8e-29 100.8 6.8 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EOO03947.1 - 0.00023 20.9 15.7 0.0028 17.4 5.1 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4311 PF14188.1 EOO03947.1 - 0.0084 15.6 2.4 0.0084 15.6 1.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4311) Peptidase_S41 PF03572.13 EOO03948.1 - 0.0067 15.8 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 ExoD PF06055.7 EOO03949.1 - 0.17 10.9 3.0 1.1 8.3 0.8 2.1 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD GYR PF02756.9 EOO03949.1 - 3.7 7.4 10.2 8.7 6.2 4.3 2.5 2 0 0 2 2 2 0 GYR motif ORC4_C PF14629.1 EOO03950.1 - 6.8e-58 195.4 0.0 1.1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD_2 PF13831.1 EOO03950.1 - 4e-14 51.6 1.7 4e-14 51.6 1.2 1.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EOO03950.1 - 7.5e-11 41.5 5.2 1.3e-10 40.7 3.6 1.4 1 0 0 1 1 1 1 PHD-finger AAA_16 PF13191.1 EOO03950.1 - 1.9e-09 37.7 1.1 1.1e-06 28.7 0.3 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EOO03950.1 - 0.00013 22.0 0.4 0.00051 20.1 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EOO03950.1 - 0.00014 22.0 1.2 0.001 19.2 0.8 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) C1_1 PF00130.17 EOO03950.1 - 0.0034 17.0 0.3 0.0077 15.9 0.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NACHT PF05729.7 EOO03950.1 - 0.0051 16.4 0.2 0.3 10.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 EOO03950.1 - 0.023 14.2 0.1 0.091 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain FYVE_2 PF02318.11 EOO03950.1 - 0.023 14.5 0.7 0.023 14.5 0.5 1.7 2 0 0 2 2 1 0 FYVE-type zinc finger AAA_14 PF13173.1 EOO03950.1 - 0.085 12.7 0.1 0.3 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain C1_3 PF07649.7 EOO03950.1 - 0.15 12.1 4.7 0.31 11.1 3.2 1.6 1 0 0 1 1 1 0 C1-like domain Prok-RING_1 PF14446.1 EOO03950.1 - 0.26 11.0 2.6 0.52 10.0 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_clus PF00172.13 EOO03951.1 - 3.2e-06 26.9 11.7 5e-06 26.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Catalase PF00199.14 EOO03952.1 - 5.3e-60 203.1 0.0 6.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Catalase ABC_tran PF00005.22 EOO03953.1 - 2.8e-22 79.4 0.0 3.8e-09 36.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EOO03953.1 - 1.2e-09 38.5 0.0 0.0096 15.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EOO03953.1 - 1.3e-08 34.6 0.0 0.00024 20.9 0.1 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EOO03953.1 - 7.7e-06 26.7 0.0 0.062 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EOO03953.1 - 0.00043 20.6 0.1 0.072 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EOO03953.1 - 0.0008 18.8 0.1 0.057 12.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EOO03953.1 - 0.00094 19.3 0.0 0.92 9.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EOO03953.1 - 0.0041 17.5 0.0 0.95 9.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EOO03953.1 - 0.0056 16.1 0.0 2.6 7.4 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EOO03953.1 - 0.025 14.5 1.9 5.7 6.8 0.3 2.9 2 2 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EOO03953.1 - 0.037 13.9 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EOO03953.1 - 0.041 13.1 0.1 2.8 7.0 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EOO03953.1 - 0.074 12.4 0.0 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EOO03953.1 - 0.089 12.6 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EOO03953.1 - 0.097 12.8 0.1 0.8 9.9 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EOO03953.1 - 0.11 11.8 0.1 5.1 6.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EOO03953.1 - 0.13 12.4 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EOO03953.1 - 0.16 12.2 0.0 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EOO03953.1 - 0.18 11.5 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EOO03953.1 - 0.22 11.1 0.0 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EOO03953.1 - 0.23 10.4 0.0 4 6.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 EOO03953.1 - 0.26 10.8 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EOO03953.1 - 0.35 9.2 0.1 0.51 8.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EOO03954.1 - 6.2e-16 58.8 0.2 3.1e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EOO03954.1 - 1.2e-05 24.9 0.0 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EOO03954.1 - 0.00042 20.4 0.2 0.003 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EOO03954.1 - 0.0018 19.0 1.7 0.019 15.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EOO03954.1 - 0.0019 17.8 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EOO03954.1 - 0.01 15.8 0.2 0.036 14.0 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EOO03954.1 - 0.075 13.3 2.1 0.23 11.7 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EOO03954.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 EOO03955.1 - 0.024 14.9 5.6 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Cupin_6 PF12852.2 EOO03955.1 - 0.045 13.3 1.8 0.094 12.3 0.4 2.1 2 0 0 2 2 2 0 Cupin Transp_cyt_pur PF02133.10 EOO03956.1 - 5.3e-25 87.8 30.5 3.7e-24 85.0 21.1 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3938 PF13074.1 EOO03956.1 - 1.1 9.0 11.3 0.061 13.1 1.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3938) Sec7 PF01369.15 EOO03957.1 - 6.1e-61 205.4 0.0 1e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EOO03957.1 - 5.8e-19 68.1 0.3 1.4e-11 44.1 0.1 3.1 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal STAT_bind PF02864.10 EOO03957.1 - 0.24 10.9 0.1 0.46 10.0 0.1 1.5 1 0 0 1 1 1 0 STAT protein, DNA binding domain p450 PF00067.17 EOO03958.1 - 1.4e-52 178.7 0.0 2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EOO03959.1 - 1.6e-20 73.8 0.0 3.8e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO03959.1 - 1.2e-10 41.5 4.4 2e-06 28.0 2.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EOO03959.1 - 6.8e-08 31.8 0.0 0.00014 20.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EOO03959.1 - 9.5e-08 32.3 1.7 0.00054 20.0 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO03959.1 - 0.0016 17.4 9.1 0.46 9.3 6.3 3.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EOO03959.1 - 0.0035 16.3 0.5 0.3 9.9 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Mon1 PF03164.9 EOO03959.1 - 0.006 15.2 0.0 0.0084 14.7 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 TrkA_N PF02254.13 EOO03959.1 - 0.0067 16.4 0.8 0.98 9.4 0.0 2.9 2 1 1 3 3 3 1 TrkA-N domain HI0933_like PF03486.9 EOO03959.1 - 0.021 13.3 2.4 2.3 6.5 0.0 3.5 3 1 1 4 4 4 0 HI0933-like protein Thi4 PF01946.12 EOO03959.1 - 0.047 12.7 2.5 2.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EOO03959.1 - 0.057 13.4 0.3 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EOO03959.1 - 0.096 12.4 0.9 5.5 6.7 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding F1F0-ATPsyn_F PF10791.4 EOO03960.1 - 3e-41 139.5 0.9 3.3e-41 139.4 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RNase_T PF00929.19 EOO03961.1 - 3.6e-26 92.3 0.0 5.4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EOO03961.1 - 0.0083 15.6 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.2 EOO03962.1 - 7.9e-65 215.2 10.7 2.5e-22 79.0 0.3 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EOO03962.1 - 2.5e-63 206.8 18.2 4e-09 35.8 0.1 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EOO03962.1 - 3.7e-55 183.3 7.7 9.9e-14 51.4 0.1 7.1 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO03962.1 - 2.7e-47 154.0 7.6 6.8e-06 25.8 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 EOO03962.1 - 1.3e-40 136.4 16.1 1.5e-09 37.8 0.2 7.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF2984 PF11203.3 EOO03962.1 - 1.6 8.8 7.3 0.67 10.1 1.8 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2984) DUF427 PF04248.7 EOO03963.1 - 2.5e-30 103.9 1.0 2.8e-30 103.8 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) GFA PF04828.9 EOO03964.1 - 5.7e-15 55.0 0.0 5.7e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HypD PF01924.11 EOO03964.1 - 0.0081 14.9 0.2 0.01 14.6 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase formation hypA family LSM PF01423.17 EOO03965.1 - 8.2e-16 57.3 0.0 1.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EOO03965.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3552 PF12072.3 EOO03966.1 - 0.054 12.7 1.1 0.078 12.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2782 PF11191.3 EOO03966.1 - 0.17 11.8 0.4 0.48 10.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) SMC_N PF02463.14 EOO03967.1 - 7e-65 218.3 20.6 1.2e-63 214.3 14.3 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EOO03967.1 - 5e-23 81.3 0.7 2.2e-22 79.2 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EOO03967.1 - 3.9e-12 46.7 9.0 3.5e-05 23.9 0.2 4.1 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EOO03967.1 - 2e-10 41.3 19.3 2e-10 41.3 13.4 6.9 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EOO03967.1 - 0.00087 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 EOO03967.1 - 0.0022 17.3 31.8 0.0022 17.3 22.1 6.0 4 2 2 6 6 6 1 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EOO03967.1 - 1 8.4 36.5 0.067 12.3 1.0 6.0 3 2 4 7 7 7 0 Reovirus sigma C capsid protein ADH_N PF08240.7 EOO03968.1 - 2.9e-10 39.8 1.8 2.2e-09 37.0 0.1 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO03968.1 - 0.00038 21.3 0.0 0.00064 20.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO03968.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.18 EOO03969.1 - 1.8e-42 144.4 0.1 3.9e-42 143.4 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EOO03969.1 - 3.6e-42 144.0 0.0 5.5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EOO03969.1 - 0.0014 17.4 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EOO03969.1 - 0.09 13.0 0.3 0.53 10.5 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3672 PF12421.3 EOO03970.1 - 0.081 13.0 5.7 5.3 7.1 3.9 2.4 1 1 0 1 1 1 0 Fibronectin type III protein CBM_4_9 PF02018.12 EOO03970.1 - 9.8 6.1 17.9 0.037 14.0 2.1 3.2 2 2 0 3 3 3 0 Carbohydrate binding domain 2OG-FeII_Oxy_2 PF13532.1 EOO03971.1 - 7e-35 120.6 0.0 9.3e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EOO03971.1 - 1.1e-09 37.9 3.8 2.3e-09 37.0 2.6 1.5 1 0 0 1 1 1 1 GRF zinc finger UTRA PF07702.8 EOO03971.1 - 0.036 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 UTRA domain 2OG-FeII_Oxy PF03171.15 EOO03971.1 - 0.037 14.3 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EOO03971.1 - 0.091 12.2 0.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 CUE domain Adaptin_N PF01602.15 EOO03972.1 - 5.9e-133 443.9 7.6 7.3e-133 443.6 5.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EOO03972.1 - 1.2e-18 67.6 2.5 1.9e-18 66.9 0.1 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EOO03972.1 - 7.5e-17 61.3 7.7 3.4e-11 43.2 0.1 4.8 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EOO03972.1 - 6.4e-13 47.6 3.9 0.00016 21.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.3 EOO03972.1 - 0.00046 19.6 1.9 0.59 9.4 0.0 3.3 3 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EOO03972.1 - 0.00071 19.9 13.9 0.028 14.9 0.1 6.4 6 1 1 7 7 7 1 HEAT-like repeat Atx10homo_assoc PF09759.4 EOO03972.1 - 0.00079 19.1 0.0 0.4 10.4 0.0 3.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EOO03972.1 - 0.0033 17.2 1.2 3.7 7.5 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EOO03972.1 - 0.013 15.4 1.2 0.37 10.7 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) DNA_alkylation PF08713.6 EOO03972.1 - 0.089 12.2 0.1 8.6 5.8 0.0 3.2 2 2 1 3 3 3 0 DNA alkylation repair enzyme T_hemolysin PF12261.3 EOO03972.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Thermostable hemolysin Mob1_phocein PF03637.12 EOO03973.1 - 5.2e-23 81.6 0.0 8.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family KR PF08659.5 EOO03974.1 - 1.9e-47 161.2 9.2 1.6e-32 112.6 0.3 2.9 2 1 1 3 3 3 2 KR domain adh_short PF00106.20 EOO03974.1 - 4.4e-38 130.8 9.7 2.1e-23 83.0 0.2 3.6 3 1 1 4 4 4 2 short chain dehydrogenase ADH_zinc_N PF00107.21 EOO03974.1 - 1.6e-19 69.7 0.0 4.9e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO03974.1 - 7.7e-14 52.6 0.0 2.9e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO03974.1 - 1.8e-09 37.3 0.4 4.5e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EOO03974.1 - 1.8e-08 34.5 0.1 4.6e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EOO03974.1 - 0.00018 21.0 0.3 0.0054 16.1 0.1 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EOO03974.1 - 0.01 14.7 0.3 0.031 13.1 0.1 1.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EOO03974.1 - 0.01 15.0 1.0 0.14 11.4 0.1 2.3 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 EOO03974.1 - 0.011 15.7 2.1 3 7.8 0.1 3.1 3 0 0 3 3 3 0 NADH(P)-binding DUF3453 PF11935.3 EOO03974.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Pyr_redox PF00070.22 EOO03974.1 - 0.021 15.2 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 EOO03974.1 - 0.052 12.2 0.1 0.09 11.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DEAD PF00270.24 EOO03975.1 - 2.3e-40 137.8 0.1 3.8e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO03975.1 - 6.7e-20 70.7 0.0 1.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EOO03975.1 - 2e-14 52.8 0.0 4.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EOO03975.1 - 0.0084 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DSPc PF00782.15 EOO03976.1 - 1.6e-12 47.1 0.0 1.8e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EOO03976.1 - 0.037 12.9 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EOO03976.1 - 0.06 13.5 0.1 0.18 12.0 0.0 1.9 2 1 0 2 2 2 0 Tyrosine phosphatase family Ribosomal_L23 PF00276.15 EOO03977.1 - 1.1e-14 54.1 0.0 1.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 MRP-L46 PF11788.3 EOO03977.1 - 0.1 13.2 1.6 0.17 12.5 1.1 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 TFIIA PF03153.8 EOO03978.1 - 9.9 5.9 9.1 13 5.6 6.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit La PF05383.12 EOO03979.1 - 2.8e-13 49.4 0.0 4.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EOO03979.1 - 2.9e-09 36.4 0.3 5.2e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO03979.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO03979.1 - 2.4e-05 24.0 0.1 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 EOO03981.1 - 5.9e-15 54.7 0.5 5.9e-15 54.7 0.3 2.3 3 0 0 3 3 3 1 DnaJ domain Peptidase_S41 PF03572.13 EOO03984.1 - 4.5e-07 29.4 0.0 1.1e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 CASP_C PF08172.7 EOO03984.1 - 0.12 11.4 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 CASP C terminal DHquinase_I PF01487.10 EOO03985.1 - 7.8e-27 94.3 0.0 1.4e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EOO03985.1 - 6.3e-19 68.3 0.1 1.4e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EOO03985.1 - 2.1e-14 53.3 0.1 5.3e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EOO03985.1 - 4.3e-13 49.5 0.1 1.1e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EOO03985.1 - 0.034 14.5 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EOO03985.1 - 0.18 11.5 0.1 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 ThiF family Fungal_trans PF04082.13 EOO03986.1 - 1.8e-27 95.8 0.0 3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BatA PF07584.6 EOO03986.1 - 0.032 14.4 0.8 17 5.7 0.2 3.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal MFS_1 PF07690.11 EOO03987.1 - 3.5e-29 101.6 33.6 3.5e-29 101.6 23.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.16 EOO03988.1 - 1.4e-11 43.9 0.0 1.6e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.10 EOO03989.1 - 9.3e-15 54.1 7.7 1.1e-14 53.8 5.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bud13 PF09736.4 EOO03990.1 - 6.9e-47 159.3 5.8 6.9e-47 159.3 4.0 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Bac_rhamnosid PF05592.6 EOO03992.1 - 4.1e-108 361.7 2.4 4.7e-108 361.6 1.7 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EOO03992.1 - 0.00096 17.9 1.4 0.0016 17.2 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 RNA_ligase PF09414.5 EOO03993.1 - 3.9e-20 72.4 0.0 6.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase MFS_1 PF07690.11 EOO03995.1 - 5.3e-42 143.7 48.4 5.3e-42 143.7 33.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 EOO03996.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 F-box-like Chitin_synth_1 PF01644.12 EOO03997.1 - 4.8e-84 280.1 0.3 7.2e-84 279.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EOO03997.1 - 1.1e-32 111.4 0.1 2.4e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EOO03997.1 - 1e-23 83.5 2.7 3.2e-20 72.0 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EOO03997.1 - 2.2e-09 37.2 0.2 2.2e-09 37.2 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EOO03997.1 - 2.5e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1237 PF06824.6 EOO03998.1 - 3.5e-171 569.4 0.0 4.1e-171 569.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Phosphoesterase PF04185.9 EOO03999.1 - 4.2e-30 105.1 1.8 1.7e-28 99.8 0.4 2.8 1 1 1 2 2 2 2 Phosphoesterase family DUF4066 PF13278.1 EOO04000.1 - 5.4e-24 84.3 0.2 3.7e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EOO04000.1 - 2.5e-06 27.0 0.0 6.7e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Haemocyan_bet_s PF14830.1 EOO04000.1 - 0.04 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Polysacc_deac_1 PF01522.16 EOO04001.1 - 8.7e-13 47.9 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EOO04001.1 - 0.081 12.3 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Peptidase_S28 PF05577.7 EOO04002.1 - 1.8e-47 161.9 0.1 1.3e-46 159.1 0.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 MOSC PF03473.12 EOO04002.1 - 0.01 15.3 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 MOSC domain SET PF00856.23 EOO04003.1 - 2.4e-08 34.4 0.1 7.5e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 SET domain Tet_JBP PF12851.2 EOO04003.1 - 0.11 11.7 0.1 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF479 PF04336.7 EOO04003.1 - 0.12 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF479 NAD_binding_2 PF03446.10 EOO04004.1 - 1.1e-22 80.6 0.0 2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EOO04004.1 - 0.0001 22.3 0.2 0.00027 20.9 0.2 1.7 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EOO04004.1 - 0.001 19.1 0.3 0.0017 18.4 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EOO04004.1 - 0.026 13.8 0.3 0.079 12.3 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amidase PF01425.16 EOO04004.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Amidase Fungal_trans PF04082.13 EOO04005.1 - 1.6e-09 37.0 0.0 2.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATG16 PF08614.6 EOO04006.1 - 0.95 9.2 10.9 0.52 10.1 3.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EOO04006.1 - 2.5 7.9 11.4 3.7 7.4 2.4 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Ferrochelatase PF00762.14 EOO04008.1 - 3.1e-87 292.4 0.0 3.5e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Nop53 PF07767.6 EOO04009.1 - 7.3e-107 357.7 30.2 9.4e-107 357.3 20.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.6 EOO04009.1 - 0.3 9.3 19.0 0.4 8.8 13.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1515 PF07439.6 EOO04009.1 - 0.51 10.1 3.9 1.5 8.6 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RNA_pol_Rpb8 PF03870.10 EOO04010.1 - 8.1e-37 126.4 0.0 9.1e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 MOSC_N PF03476.11 EOO04011.1 - 3.3e-12 46.1 0.0 5.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EOO04011.1 - 3.2e-11 42.8 0.0 5.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain ThiF PF00899.16 EOO04012.1 - 4.1e-12 46.0 0.0 9.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 ThiF family Thioredoxin PF00085.15 EOO04014.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin PTR2 PF00854.16 EOO04015.1 - 3.9e-25 88.4 2.6 3.9e-25 88.4 1.8 2.2 2 1 0 2 2 2 1 POT family WD40 PF00400.27 EOO04016.1 - 3.2e-25 87.0 2.1 1.2e-08 34.4 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat OPT PF03169.10 EOO04017.1 - 1.8e-144 482.5 45.1 2.1e-144 482.3 31.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 2-Hacid_dh_C PF02826.14 EOO04019.1 - 3.3e-44 150.1 0.0 4.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EOO04019.1 - 2.5e-05 23.7 0.0 8.4e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.16 EOO04019.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 EOO04019.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.1 EOO04019.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EOO04019.1 - 0.039 13.7 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3146 PF11344.3 EOO04019.1 - 0.15 11.5 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) OPT PF03169.10 EOO04020.1 - 1.2e-90 304.7 18.9 1.6e-90 304.3 13.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPR_11 PF13414.1 EOO04021.1 - 5.9e-08 32.2 0.1 0.00027 20.5 0.0 4.2 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 EOO04021.1 - 0.0014 18.6 0.2 0.18 12.0 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_26 PF13500.1 EOO04021.1 - 0.0018 17.9 0.1 0.072 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 EOO04021.1 - 0.0061 17.1 0.7 0.12 13.0 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 EOO04021.1 - 0.0097 15.9 0.1 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.12 EOO04021.1 - 0.015 15.1 1.3 0.57 10.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EOO04021.1 - 0.021 15.2 7.3 0.73 10.4 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EOO04021.1 - 0.035 14.0 1.0 1.6 8.6 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 EOO04021.1 - 0.11 12.6 0.8 4.1 7.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain EFP PF01132.15 EOO04021.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain TPR_1 PF00515.23 EOO04021.1 - 0.21 11.2 4.0 2 8.1 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Snf7 PF03357.16 EOO04022.1 - 1.2e-30 106.1 28.1 1.2e-30 106.1 19.5 2.0 1 1 1 2 2 2 2 Snf7 Allexi_40kDa PF05549.6 EOO04022.1 - 1.4 8.1 8.7 3.6 6.7 6.0 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein Sugar_tr PF00083.19 EOO04023.1 - 4.4e-114 381.5 29.6 5.2e-114 381.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04023.1 - 1.3e-22 80.0 52.6 2.8e-20 72.3 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO04023.1 - 1.1e-07 30.5 28.9 5.8e-05 21.6 6.7 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein Lipoxygenase PF00305.14 EOO04024.1 - 2.1e-30 105.3 0.0 3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Polysacc_deac_1 PF01522.16 EOO04025.1 - 1.8e-10 40.4 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.3 EOO04025.1 - 0.088 12.2 0.1 0.31 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) GMC_oxred_C PF05199.8 EOO04026.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 EOO04027.1 - 1.4e-20 73.3 31.4 1.3e-13 50.4 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_N PF00134.18 EOO04028.1 - 0.012 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Beta-lactamase PF00144.19 EOO04029.1 - 0.0099 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 EOO04030.1 - 1.9e-37 128.7 31.0 1.9e-37 128.7 21.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pept_tRNA_hydro PF01195.14 EOO04031.1 - 9.2e-27 93.7 0.0 1.1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase adh_short PF00106.20 EOO04032.1 - 3.4e-15 56.3 0.1 4.8e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO04032.1 - 6.8e-10 39.1 0.0 9.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO04032.1 - 0.0002 21.0 0.2 0.00048 19.8 0.2 1.6 1 1 0 1 1 1 1 KR domain Sugar_tr PF00083.19 EOO04033.1 - 1.3e-26 93.2 21.3 1.6e-26 92.8 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04033.1 - 1.5e-06 27.2 14.9 1.8e-06 26.8 10.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2854 PF11016.3 EOO04033.1 - 0.085 12.3 0.2 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) Dioxygenase_C PF00775.16 EOO04034.1 - 4.7e-12 45.5 0.2 7.6e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase GrpB PF04229.9 EOO04035.1 - 2.2e-50 170.6 0.0 2.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 GrpB protein DUF4448 PF14610.1 EOO04036.1 - 6.4e-31 107.3 0.0 1.6e-30 106.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EOO04036.1 - 7.7e-06 25.1 0.7 2.1e-05 23.7 0.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EOO04036.1 - 0.1 12.1 0.5 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 BAR PF03114.13 EOO04037.1 - 1.2e-57 195.0 2.0 1.5e-57 194.7 1.4 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 EOO04037.1 - 0.076 13.4 0.9 0.58 10.6 0.0 2.6 3 0 0 3 3 3 0 CP12 domain Peptidase_S8 PF00082.17 EOO04038.1 - 6.5e-16 58.3 0.2 1.2e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EOO04038.1 - 1.9e-11 44.1 0.0 4.7e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EOO04038.1 - 3.6e-09 36.9 0.1 0.0058 17.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO04038.1 - 6.6e-07 28.9 0.0 0.048 13.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EOO04038.1 - 2.2e-06 27.1 0.0 0.011 15.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EOO04038.1 - 0.049 13.8 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Atrophin-1 PF03154.10 EOO04038.1 - 0.076 11.1 4.3 0.12 10.4 3.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family Adap_comp_sub PF00928.16 EOO04039.1 - 9.8e-86 287.0 0.0 1.3e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EOO04039.1 - 3.1e-05 23.7 0.2 5.6e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EOO04039.1 - 0.023 14.5 0.2 0.058 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Protoglobin PF11563.3 EOO04040.1 - 1.1e-37 129.1 0.0 1.5e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Bestrophin PF01062.16 EOO04041.1 - 2.8e-41 141.3 0.5 3.6e-26 91.7 0.1 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FAA_hydrolase PF01557.13 EOO04042.1 - 1.1e-61 208.0 0.0 1.5e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 EOO04043.1 - 4.1e-16 58.6 54.2 2.8e-08 32.8 28.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF543 PF04418.7 EOO04043.1 - 0.17 11.8 1.8 0.78 9.7 1.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF4381 PF14316.1 EOO04043.1 - 0.28 11.3 3.6 9.5 6.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) F_bP_aldolase PF01116.15 EOO04044.1 - 1.5e-56 191.6 0.0 1.7e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.11 EOO04045.1 - 1.7e-32 112.5 27.1 1.7e-32 112.5 18.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Ammonium_transp PF00909.16 EOO04046.1 - 8.4e-118 393.2 27.3 9.6e-118 393.1 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_6 PF01341.12 EOO04047.1 - 7.9e-106 353.8 5.4 1e-105 353.4 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 BAR PF03114.13 EOO04048.1 - 2.2e-53 181.1 7.0 2.6e-53 180.9 4.8 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EOO04048.1 - 1.5e-06 27.3 2.2 1.6e-06 27.2 1.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.8 EOO04048.1 - 0.0019 17.5 4.0 0.0026 17.1 2.8 1.3 1 0 0 1 1 1 1 Arfaptin-like domain Myosin_tail_1 PF01576.14 EOO04048.1 - 0.0031 15.3 7.7 0.0048 14.7 5.3 1.2 1 0 0 1 1 1 1 Myosin tail Herpes_UL25 PF01499.11 EOO04048.1 - 0.03 12.6 2.9 0.04 12.2 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family APG6 PF04111.7 EOO04048.1 - 0.075 12.0 9.8 0.046 12.7 5.6 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EOO04048.1 - 0.63 9.6 7.0 1 8.9 4.8 1.3 1 0 0 1 1 1 0 IncA protein Aldo_ket_red PF00248.16 EOO04049.1 - 3.6e-61 206.4 0.0 4.1e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.21 EOO04050.1 - 4.7e-28 97.3 0.0 9.4e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EOO04050.1 - 8.9e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 UEV domain Auto_anti-p27 PF06677.7 EOO04050.1 - 0.013 15.2 0.8 0.026 14.2 0.0 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Bclx_interact PF08945.5 EOO04050.1 - 0.095 12.2 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain IBR PF01485.16 EOO04050.1 - 0.12 12.2 7.2 0.38 10.6 5.0 1.8 1 1 0 1 1 1 0 IBR domain DUF4387 PF14330.1 EOO04051.1 - 8.6e-36 122.2 0.0 1.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EOO04051.1 - 3.7e-15 55.2 0.0 2.9e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1446) DUF2183 PF09949.4 EOO04052.1 - 1.7e-29 101.7 0.0 3.7e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GST_C_3 PF14497.1 EOO04053.1 - 2.2e-10 40.8 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EOO04053.1 - 1e-07 31.7 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EOO04053.1 - 0.00082 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EOO04053.1 - 0.001 19.1 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 EOO04054.1 - 2.7e-79 266.8 32.8 3.2e-79 266.6 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04054.1 - 3.5e-16 58.8 35.9 3.5e-16 58.8 24.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Amino_oxidase PF01593.19 EOO04055.1 - 1.5e-48 166.0 0.0 1.9e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EOO04055.1 - 1.8e-10 40.6 0.0 5.7e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EOO04055.1 - 0.0002 20.3 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EOO04055.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EOO04055.1 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EOO04055.1 - 0.045 13.5 0.9 0.079 12.7 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EOO04055.1 - 0.048 12.1 0.4 0.072 11.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EOO04055.1 - 0.14 11.2 0.4 0.22 10.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EOO04055.1 - 0.17 12.3 0.5 0.38 11.1 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EOO04056.1 - 3e-29 101.8 32.5 6.9e-29 100.6 22.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2678 PF10856.3 EOO04056.1 - 0.011 15.4 0.4 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Sugar_tr PF00083.19 EOO04057.1 - 2.4e-74 250.5 24.9 2.9e-74 250.2 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04057.1 - 2.4e-19 69.2 25.9 2.4e-19 69.2 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MotB_plug PF13677.1 EOO04057.1 - 0.26 10.6 4.0 0.29 10.4 1.5 2.0 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB DUF3792 PF12670.2 EOO04057.1 - 8.2 6.3 26.0 1.7 8.4 1.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) GSDH PF07995.6 EOO04059.1 - 3.2e-06 26.4 0.8 1.2e-05 24.6 0.3 2.1 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EOO04059.1 - 0.00013 21.7 0.1 19 5.4 0.0 5.0 5 0 0 5 5 5 2 NHL repeat RCC1_2 PF13540.1 EOO04059.1 - 0.0072 15.9 2.2 0.78 9.4 0.1 2.9 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EOO04060.1 - 1.1e-46 157.0 1.4 9.2e-16 57.9 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EOO04060.1 - 8.4e-40 132.6 12.9 8.8e-07 28.4 0.0 8.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EOO04060.1 - 9.3e-37 124.7 3.4 1.5e-06 28.5 0.0 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EOO04060.1 - 3.1e-33 113.0 8.4 5.2e-09 36.0 0.4 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO04060.1 - 1.4e-31 105.3 4.3 4.5e-05 23.2 0.0 7.6 7 1 0 7 7 7 7 Ankyrin repeat Formyl_trans_N PF00551.14 EOO04061.1 - 1.7e-37 128.6 0.1 2.2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EOO04061.1 - 2.7e-10 39.5 0.0 6.2e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EOO04061.1 - 0.018 14.7 0.0 0.059 13.0 0.0 2.0 1 1 0 1 1 1 0 ACT domain AAA PF00004.24 EOO04062.1 - 0.0056 16.8 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IU_nuc_hydro PF01156.14 EOO04063.1 - 5.1e-68 229.5 0.0 6.1e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase NEL PF14496.1 EOO04066.1 - 0.016 14.4 0.1 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting zf-rbx1 PF12678.2 EOO04067.1 - 0.48 10.5 4.3 1.5 8.9 3.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger Sec63 PF02889.11 EOO04068.1 - 8.4e-45 153.3 0.0 1.1e-43 149.6 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EOO04068.1 - 2.5e-17 62.3 0.9 6.3e-17 61.0 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain PAP2_3 PF14378.1 EOO04069.1 - 1.7e-21 76.6 11.4 2.9e-17 62.8 2.7 2.3 2 0 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.1 EOO04069.1 - 0.084 13.1 0.6 0.084 13.1 0.4 3.2 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Acetyltransf_1 PF00583.19 EOO04070.1 - 0.00075 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EOO04070.1 - 0.0016 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EOO04070.1 - 0.0026 17.8 0.0 0.0096 16.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2347 PF09804.4 EOO04071.1 - 8.7e-91 304.0 0.0 2.1e-65 220.8 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EOO04071.1 - 9.3e-40 136.5 1.5 1.7e-39 135.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Peroxidase_2 PF01328.12 EOO04072.1 - 1.2e-06 27.4 0.1 1.3e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Lectin_leg-like PF03388.8 EOO04073.1 - 7.4e-65 218.2 0.0 9.7e-65 217.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EOO04073.1 - 0.039 13.3 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain Bac_luciferase PF00296.15 EOO04074.1 - 6.4e-57 193.0 0.2 9.7e-57 192.4 0.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Isochorismatase PF00857.15 EOO04074.1 - 5.3e-13 49.2 0.0 3.8e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Isochorismatase family Hydantoinase_A PF01968.13 EOO04075.1 - 4.3e-84 282.0 1.3 6.1e-84 281.5 0.9 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EOO04075.1 - 2.4e-12 46.7 0.9 1.9e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_B PF02538.9 EOO04075.1 - 5.4e-12 44.7 0.0 8.1e-12 44.1 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase MutL PF13941.1 EOO04075.1 - 0.0052 15.1 0.2 0.013 13.9 0.1 1.6 1 0 0 1 1 1 1 MutL protein Hydrolase_6 PF13344.1 EOO04076.1 - 2e-14 53.3 0.0 4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EOO04076.1 - 5.4e-12 45.2 0.1 3.3e-11 42.7 0.1 2.1 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EOO04076.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 EOO04077.1 - 1.2e-50 172.3 0.0 1.6e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hexokinase_1 PF00349.16 EOO04078.1 - 9.4e-25 87.1 0.0 1.1e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Hexokinase dCMP_cyt_deam_1 PF00383.17 EOO04079.1 - 9.7e-14 50.8 0.0 1.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EOO04079.1 - 0.073 12.6 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Acyltransferase PF01553.16 EOO04080.1 - 9.4e-34 115.7 0.0 1.5e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EOO04080.1 - 0.034 13.8 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP Actin PF00022.14 EOO04081.1 - 2.8e-30 105.0 0.0 1.4e-18 66.5 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EOO04081.1 - 0.018 13.6 0.0 0.25 9.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Baculo_11_kDa PF06143.6 EOO04082.1 - 0.017 14.4 0.4 0.041 13.2 0.2 1.5 1 1 0 1 1 1 0 Baculovirus 11 kDa family DUF2235 PF09994.4 EOO04083.1 - 3.1e-38 131.7 0.0 4.4e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EOO04083.1 - 0.044 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Afi1 PF07792.7 EOO04084.1 - 1.6e-66 222.8 0.3 3e-66 221.9 0.2 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EOO04084.1 - 2.5e-37 127.0 0.0 4.9e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EOO04084.1 - 7.5e-08 31.2 0.1 0.01 14.3 0.0 4.0 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EOO04084.1 - 0.011 14.9 0.0 0.1 11.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF3295 PF11702.3 EOO04084.1 - 0.015 14.3 7.6 0.023 13.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF1168 PF06658.7 EOO04084.1 - 0.019 14.4 12.4 0.045 13.2 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Astro_capsid PF03115.9 EOO04084.1 - 0.057 11.6 1.2 0.084 11.1 0.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIA PF03153.8 EOO04084.1 - 0.2 11.5 10.3 0.31 10.8 7.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EOO04084.1 - 0.22 9.4 17.1 0.31 8.9 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family FLO_LFY PF01698.11 EOO04084.1 - 0.27 10.0 6.0 0.43 9.3 4.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ebola_NP PF05505.7 EOO04084.1 - 0.73 7.8 8.6 1.2 7.0 6.0 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein RNA_pol_3_Rpc31 PF11705.3 EOO04084.1 - 0.81 9.5 23.3 1.5 8.6 16.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 EOO04084.1 - 0.83 8.6 17.1 1.3 7.9 11.8 1.2 1 0 0 1 1 1 0 BUD22 Protocadherin PF08374.6 EOO04084.1 - 0.88 9.1 5.0 1.7 8.2 3.5 1.4 1 0 0 1 1 1 0 Protocadherin Cwf_Cwc_15 PF04889.7 EOO04084.1 - 1 9.0 18.0 2.1 8.0 12.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EOO04084.1 - 4.7 5.5 16.2 7.8 4.8 11.2 1.2 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 EOO04084.1 - 4.8 5.9 10.1 12 4.6 6.5 1.8 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 EOO04085.1 - 2.2e-24 86.0 2.5 2.7e-24 85.7 1.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 EOO04085.1 - 0.32 9.9 1.7 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase DUF2834 PF11196.3 EOO04085.1 - 0.38 10.9 3.1 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) ICMT PF04140.9 EOO04086.1 - 2.4e-28 98.1 1.1 6.6e-28 96.7 0.8 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EOO04086.1 - 6.2e-14 51.9 2.7 6.2e-14 51.9 1.9 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EOO04086.1 - 0.00043 19.6 2.5 0.00043 19.6 1.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2371 PF10177.4 EOO04086.1 - 0.069 13.0 0.5 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Glyco_hydro_16 PF00722.16 EOO04087.1 - 1.3e-10 40.8 0.5 2.1e-10 40.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Esterase PF00756.15 EOO04088.1 - 9.3e-53 179.2 0.0 1.1e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EOO04088.1 - 1.5e-06 28.0 0.1 1.8e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EOO04088.1 - 6.3e-06 25.5 0.3 2.9e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EOO04088.1 - 1.9e-05 24.6 3.2 2.6e-05 24.2 2.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EOO04088.1 - 0.0019 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EOO04088.1 - 0.0024 16.8 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EOO04088.1 - 0.0081 15.3 0.3 0.016 14.4 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EOO04088.1 - 0.11 11.2 0.1 0.21 10.3 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase LCAT PF02450.10 EOO04088.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Mtc PF03820.12 EOO04090.1 - 1.7e-101 338.9 0.1 1.5e-100 335.8 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier DUF3586 PF12131.3 EOO04091.1 - 0.018 15.0 0.1 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) CorA PF01544.13 EOO04092.1 - 2.6e-09 36.5 1.8 3e-09 36.3 0.3 1.8 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein EB1 PF03271.12 EOO04092.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF4381 PF14316.1 EOO04092.1 - 0.13 12.3 1.9 0.96 9.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C2H2 PF00096.21 EOO04093.1 - 2.8e-31 105.9 58.1 0.0015 18.7 1.4 11.0 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EOO04093.1 - 4.1e-24 83.0 45.4 0.0035 17.5 0.4 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EOO04093.1 - 5.2e-20 70.6 46.7 0.00014 22.0 0.1 9.9 10 1 0 10 10 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EOO04093.1 - 1.2e-08 34.8 38.7 0.00083 19.4 0.6 9.9 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EOO04093.1 - 1.4e-08 34.6 33.4 0.017 15.3 0.2 8.9 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EOO04093.1 - 3.9e-05 23.1 4.2 2.7 7.7 0.1 4.3 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EOO04093.1 - 0.062 13.2 15.9 0.16 11.9 0.5 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Endonuc-dimeris PF09124.5 EOO04093.1 - 0.13 11.9 1.2 0.67 9.6 0.6 2.4 1 1 1 2 2 2 0 T4 recombination endonuclease VII, dimerisation MBOAT PF03062.14 EOO04094.1 - 1.4e-20 73.6 19.5 2.3e-20 72.9 13.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EOO04094.1 - 0.0026 17.7 2.3 0.011 15.7 1.6 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EOO04096.1 - 1.3e-11 43.7 28.3 2.1e-09 36.5 13.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO04096.1 - 3.5e-09 35.4 6.9 2.9e-08 32.4 4.8 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1469 PF07332.6 EOO04096.1 - 0.0099 15.6 0.5 0.0099 15.6 0.4 5.0 5 0 0 5 5 5 2 Protein of unknown function (DUF1469) DUF2040 PF09745.4 EOO04097.1 - 5.7e-34 116.7 27.0 5.7e-34 116.7 18.7 3.6 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) KH_1 PF00013.24 EOO04099.1 - 8.4e-39 131.0 13.5 1e-14 53.8 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EOO04099.1 - 4.5e-30 102.7 13.8 6e-11 41.7 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EOO04099.1 - 1.9e-09 36.9 10.5 0.0054 16.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EOO04099.1 - 3e-08 33.1 3.5 0.054 13.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EOO04099.1 - 0.00014 21.5 4.8 0.65 9.8 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EOO04099.1 - 0.0072 15.7 0.5 0.53 9.7 0.0 3.0 3 0 0 3 3 3 1 dUTPase MFS_1 PF07690.11 EOO04100.1 - 1.3e-23 83.3 31.9 3.1e-12 45.8 3.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EOO04100.1 - 2.9e-08 32.5 14.0 8e-06 24.5 1.8 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein TraL PF07178.6 EOO04100.1 - 0.28 11.2 2.4 19 5.3 0.0 3.1 2 0 0 2 2 2 0 TraL protein Hexapep_2 PF14602.1 EOO04102.1 - 1.8e-11 43.3 3.9 3e-11 42.6 2.7 1.4 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EOO04102.1 - 8.1e-11 40.9 6.2 1.3e-10 40.3 3.5 1.9 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EOO04102.1 - 3e-08 33.5 0.3 4.8e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Acetyltransf_11 PF13720.1 EOO04102.1 - 0.044 14.0 0.1 0.084 13.1 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 F-box-like PF12937.2 EOO04103.1 - 2.1e-09 36.9 0.0 7.5e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EOO04103.1 - 3.3e-08 32.7 6.5 0.021 14.8 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.28 EOO04103.1 - 1e-06 28.2 0.0 3.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EOO04103.1 - 8.2e-06 25.4 4.7 0.06 13.0 0.1 4.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EOO04103.1 - 2.4e-05 23.7 15.3 0.19 11.8 1.1 7.2 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.2 EOO04103.1 - 4.2e-05 23.0 12.0 0.0044 16.5 0.3 5.7 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) PRANC PF09372.5 EOO04103.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 PRANC domain LRR_7 PF13504.1 EOO04103.1 - 1.1 9.7 20.2 8.1 7.1 0.4 7.3 9 0 0 9 9 9 0 Leucine rich repeat SET PF00856.23 EOO04104.1 - 7.1e-08 32.9 0.0 0.00012 22.4 0.0 2.6 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EOO04104.1 - 0.037 13.6 2.9 0.43 10.2 0.8 2.5 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EOO04104.1 - 1.3 9.8 6.9 0.44 11.2 2.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Stm1_N PF09598.5 EOO04105.1 - 3.1e-08 34.2 2.3 3.1e-08 34.2 1.6 4.9 3 1 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EOO04105.1 - 0.00014 22.3 5.0 0.00014 22.3 3.4 3.3 4 0 0 4 4 4 1 Hyaluronan / mRNA binding family Lactamase_B_2 PF12706.2 EOO04106.1 - 1.7e-32 112.5 0.1 3.6e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EOO04106.1 - 7.7e-26 89.3 0.0 2.3e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EOO04106.1 - 2.9e-09 36.8 0.5 1.3e-08 34.7 0.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glucosamine_iso PF01182.15 EOO04107.1 - 3.3e-61 206.4 0.0 4e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF1762 PF08574.5 EOO04108.1 - 5.6e-09 36.2 11.2 5.6e-09 36.2 7.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) DUF4238 PF14022.1 EOO04110.1 - 3.7e-29 101.8 0.1 5.5e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF3123 PF11321.3 EOO04111.1 - 1.3 9.3 6.8 0.25 11.6 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Gly_transf_sug PF04488.10 EOO04112.1 - 4.8e-18 65.4 0.0 8.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EOO04112.1 - 0.0016 16.9 0.1 0.0074 14.8 0.0 1.8 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EOO04112.1 - 0.041 13.0 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF1206 PF06724.6 EOO04112.1 - 1.2 8.9 3.9 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) EndIII_4Fe-2S PF10576.4 EOO04113.1 - 0.31 11.3 3.2 5 7.4 0.2 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Tyrosinase PF00264.15 EOO04114.1 - 1.2e-45 156.3 0.0 1.5e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase MDMPI_N PF11716.3 EOO04115.1 - 0.013 15.9 3.0 0.013 15.9 2.0 2.6 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain Pkinase PF00069.20 EOO04116.1 - 1.9e-59 200.9 0.0 2.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04116.1 - 2.6e-20 72.6 0.0 3.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04116.1 - 2.1e-07 30.1 0.0 3.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EOO04116.1 - 5.8e-05 22.2 0.1 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EOO04116.1 - 0.0015 17.9 0.2 0.0045 16.3 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EOO04116.1 - 0.0026 17.5 0.3 0.0094 15.7 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.1 EOO04116.1 - 0.027 14.8 0.0 0.51 10.7 0.0 3.0 4 0 0 4 4 4 0 PAS domain Seadorna_VP7 PF07387.6 EOO04116.1 - 0.14 10.9 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PI-PLC-X PF00388.14 EOO04117.1 - 1.2e-62 209.6 0.0 2.8e-62 208.4 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EOO04117.1 - 3.5e-38 130.1 0.0 8.9e-38 128.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EOO04117.1 - 0.00055 19.9 0.3 0.048 13.6 0.2 2.6 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like CENP-M PF11111.3 EOO04117.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF4451 PF14616.1 EOO04118.1 - 2.7e-34 117.6 0.2 4.8e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Gelsolin PF00626.17 EOO04119.1 - 6.3e-12 45.0 0.1 7.8e-05 22.2 0.0 3.6 3 2 0 3 3 3 2 Gelsolin repeat MFS_1 PF07690.11 EOO04120.1 - 2e-42 145.2 42.8 2e-42 145.2 29.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO04120.1 - 9.5e-14 50.8 11.4 9.5e-14 50.8 7.9 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter FA_hydroxylase PF04116.8 EOO04122.1 - 1e-13 51.7 20.0 2.3e-13 50.5 11.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PepSY_2 PF13670.1 EOO04124.1 - 4.4 7.2 7.0 0.22 11.4 0.4 2.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF4124 PF13511.1 EOO04124.1 - 7.8 6.6 12.5 0.8 9.7 1.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) zf-Tim10_DDP PF02953.10 EOO04125.1 - 1e-20 72.7 1.3 1.2e-20 72.4 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 EOO04125.1 - 0.072 12.8 1.2 0.11 12.3 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TIL PF01826.12 EOO04125.1 - 0.097 12.7 1.9 0.14 12.2 1.3 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DEAD PF00270.24 EOO04126.1 - 1.2e-29 103.0 0.0 2.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO04126.1 - 2.5e-18 65.6 0.0 1.2e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO04126.1 - 7.6e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4045 PF13254.1 EOO04127.1 - 9.5e-81 272.2 59.9 1.7e-45 156.0 22.2 4.2 2 2 2 4 4 4 2 Domain of unknown function (DUF4045) Pkinase PF00069.20 EOO04128.1 - 1e-71 241.1 0.0 1.2e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04128.1 - 1.2e-38 132.6 0.0 1.5e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04128.1 - 2e-08 33.5 0.0 3.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EOO04128.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EOO04128.1 - 0.12 11.1 0.0 0.33 9.7 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 DLH PF01738.13 EOO04129.1 - 0.017 14.4 0.2 0.025 13.8 0.1 1.2 1 1 0 1 1 1 0 Dienelactone hydrolase family EF-hand_6 PF13405.1 EOO04130.1 - 4.5e-11 41.6 0.3 0.00045 19.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EOO04130.1 - 4.3e-09 35.0 1.0 0.0011 18.0 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EOO04130.1 - 1.3e-06 28.3 0.0 6.1e-06 26.2 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EOO04130.1 - 1.4e-06 27.4 4.5 0.0055 15.9 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EOO04130.1 - 5.1e-05 22.7 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EOO04130.1 - 0.046 13.6 0.0 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF2789 PF10982.3 EOO04130.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) PHD PF00628.24 EOO04131.1 - 4e-09 36.0 7.8 6.4e-09 35.3 5.4 1.3 1 0 0 1 1 1 1 PHD-finger PGAP1 PF07819.8 EOO04132.1 - 1.7e-06 27.8 0.1 3.7e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.10 EOO04132.1 - 0.00019 20.5 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EOO04132.1 - 0.00034 19.9 0.1 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EOO04132.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EOO04132.1 - 0.027 14.3 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO04132.1 - 0.031 14.0 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EOO04132.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Arf PF00025.16 EOO04133.1 - 1.3e-66 223.1 0.9 1.5e-66 222.9 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EOO04133.1 - 4.4e-12 45.3 1.5 3.9e-07 29.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EOO04133.1 - 7.6e-12 44.9 0.0 8.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EOO04133.1 - 8.8e-10 38.1 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EOO04133.1 - 1.8e-09 38.1 0.0 2.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO04133.1 - 1e-08 35.1 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EOO04133.1 - 3.5e-06 26.3 0.0 4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EOO04133.1 - 5.5e-06 25.9 0.0 0.0005 19.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EOO04133.1 - 0.011 15.3 0.2 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 EOO04133.1 - 0.032 15.0 0.2 0.043 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EOO04133.1 - 0.032 13.4 0.2 0.087 12.1 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EOO04133.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EOO04133.1 - 0.052 13.3 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.13 EOO04133.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Fructosamin_kin PF03881.9 EOO04134.1 - 8.3e-22 77.4 0.0 9.5e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EOO04134.1 - 0.007 16.1 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EOO04134.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PTS_2-RNA PF01885.11 EOO04135.1 - 2.6e-66 222.5 0.0 3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF572 PF04502.8 EOO04136.1 - 0.00054 19.2 19.1 0.00069 18.9 13.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF2413 PF10310.4 EOO04136.1 - 0.0045 15.8 15.4 0.0052 15.6 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) GAGA_bind PF06217.7 EOO04136.1 - 0.016 15.1 15.4 0.021 14.7 10.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 EOO04136.1 - 0.018 14.4 20.2 0.031 13.7 14.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 EOO04136.1 - 0.57 8.7 10.1 0.71 8.4 7.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 EOO04136.1 - 1.1 9.1 24.2 1.6 8.5 16.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2146 PF10220.4 EOO04136.1 - 1.9 6.3 12.8 2.5 5.9 8.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Neur_chan_memb PF02932.11 EOO04136.1 - 2.3 8.0 10.4 3.6 7.3 7.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 EOO04136.1 - 2.7 6.4 7.8 3.2 6.2 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 EOO04136.1 - 2.9 5.4 17.4 3.7 5.0 12.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.11 EOO04136.1 - 3.7 6.8 15.8 7.3 5.9 10.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Ndc1_Nup PF09531.5 EOO04136.1 - 3.9 5.7 6.5 4.5 5.5 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GMC_oxred_N PF00732.14 EOO04137.1 - 1.3e-27 96.7 0.1 2.5e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EOO04137.1 - 1.5e-23 83.6 0.3 2.8e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EOO04137.1 - 2.1e-10 40.0 0.3 0.00017 20.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.13 EOO04137.1 - 1.8e-09 37.1 12.1 5.3e-09 35.5 8.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DAO PF01266.19 EOO04137.1 - 2.1e-07 30.2 0.2 6.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO04137.1 - 0.00015 21.6 0.0 0.00053 19.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EOO04137.1 - 0.00028 20.0 0.0 0.073 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO04137.1 - 0.00034 20.5 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EOO04137.1 - 0.00038 20.3 0.1 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.9 EOO04137.1 - 0.00046 18.7 0.0 0.0011 17.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EOO04137.1 - 0.0011 19.0 0.1 0.038 14.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EOO04137.1 - 0.003 17.9 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EOO04137.1 - 0.085 11.8 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EOO04137.1 - 0.12 11.4 1.4 0.22 10.5 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EOO04137.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TPR_11 PF13414.1 EOO04138.1 - 4e-53 176.9 22.9 2e-21 75.4 4.3 5.8 4 2 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EOO04138.1 - 8.3e-47 154.9 15.8 4.5e-10 38.6 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EOO04138.1 - 1.5e-43 143.1 17.6 2.3e-07 30.1 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EOO04138.1 - 1.2e-29 102.3 20.4 1e-07 32.4 0.0 6.4 5 2 2 7 7 6 5 Tetratricopeptide repeat DnaJ PF00226.26 EOO04138.1 - 1.8e-27 94.8 6.4 2e-27 94.6 3.0 2.3 2 0 0 2 2 1 1 DnaJ domain TPR_19 PF14559.1 EOO04138.1 - 1e-25 89.8 22.8 4.2e-09 36.6 0.1 6.4 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EOO04138.1 - 1.4e-24 84.3 18.4 1.1e-05 25.5 0.1 9.1 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EOO04138.1 - 2.2e-22 77.3 15.9 0.00059 19.8 0.0 7.7 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EOO04138.1 - 3.3e-21 73.4 11.3 0.00034 20.1 0.1 7.3 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EOO04138.1 - 1.5e-19 69.6 22.2 6.4e-06 26.0 0.1 6.3 5 2 2 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EOO04138.1 - 5.6e-17 61.6 9.3 1.2e-07 31.7 1.2 3.9 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EOO04138.1 - 7.7e-16 56.5 11.0 0.18 11.6 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EOO04138.1 - 2.1e-12 46.7 16.7 0.0025 17.6 1.0 6.6 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.1 EOO04138.1 - 4.3e-10 39.1 15.8 0.00057 19.0 0.8 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EOO04138.1 - 2.4e-09 37.0 26.9 0.019 15.3 0.1 8.3 10 0 0 10 10 7 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EOO04138.1 - 3.8e-05 23.4 7.8 0.53 10.2 0.0 5.7 3 3 2 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EOO04138.1 - 0.00011 22.2 18.1 0.19 11.8 0.1 5.0 3 3 2 5 5 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EOO04138.1 - 0.00016 20.6 2.7 0.00063 18.6 0.1 2.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 EOO04138.1 - 0.00031 21.0 10.6 0.77 10.0 0.4 4.7 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 EOO04138.1 - 0.00041 20.4 3.1 0.031 14.6 0.0 4.3 4 0 0 4 4 2 1 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EOO04138.1 - 0.0014 17.4 0.8 0.0022 16.7 0.1 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.1 EOO04138.1 - 0.014 15.3 24.9 1.5 8.8 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EOO04138.1 - 0.016 15.4 6.3 1.1 9.5 0.1 4.1 1 1 3 4 4 4 0 Alkyl sulfatase dimerisation Coatomer_E PF04733.9 EOO04138.1 - 0.032 13.4 0.6 2.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Coatomer epsilon subunit SHNi-TPR PF10516.4 EOO04138.1 - 0.045 13.0 5.5 1 8.6 0.0 4.2 5 0 0 5 5 5 0 SHNi-TPR TPR_21 PF09976.4 EOO04138.1 - 0.23 11.3 18.3 0.46 10.4 0.3 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.7 EOO04138.1 - 0.25 10.9 5.5 0.34 10.5 0.2 3.2 3 1 1 4 4 3 0 Protein of unknown function (DUF627) DUF982 PF06169.7 EOO04138.1 - 0.72 9.6 3.5 14 5.4 0.0 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF982) MIT PF04212.13 EOO04138.1 - 1.7 8.5 13.3 22 4.9 1.8 4.9 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain UAA PF08449.6 EOO04139.1 - 3.8e-72 242.7 7.4 1.2e-71 241.1 5.1 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EOO04139.1 - 7.7e-07 29.1 28.1 5e-06 26.5 5.0 3.3 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EOO04139.1 - 5.8e-05 22.3 3.1 0.06 12.4 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EOO04139.1 - 0.00034 20.2 17.7 0.0012 18.5 3.7 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EOO04139.1 - 0.0014 18.8 25.8 0.0016 18.6 6.1 3.1 3 2 0 3 3 3 2 Multidrug resistance efflux transporter RNA_pol_Rpb6 PF01192.17 EOO04140.1 - 1.5e-24 85.4 0.3 2.5e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 RabGAP-TBC PF00566.13 EOO04141.1 - 2.5e-30 105.5 0.4 3.7e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EOO04142.1 - 2.5e-12 46.5 0.0 3.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04142.1 - 0.00069 18.7 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Endonuclease_NS PF01223.18 EOO04143.1 - 5.3e-59 199.3 0.0 9e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Med10 PF09748.4 EOO04144.1 - 4e-41 139.8 0.0 4.7e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PS_Dcarbxylase PF02666.10 EOO04145.1 - 1.9e-54 184.0 0.0 2.7e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EOO04145.1 - 3.6e-35 119.6 0.0 5.3e-18 64.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EOO04145.1 - 0.00081 19.4 0.1 0.0026 17.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EOO04145.1 - 0.0046 16.7 0.4 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EOO04145.1 - 0.0088 15.2 0.4 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EOO04145.1 - 0.02 14.2 0.0 0.078 12.3 0.0 2.1 1 0 0 1 1 1 0 EF hand SCP2 PF02036.12 EOO04146.1 - 1.2e-24 86.4 0.6 1.6e-24 86.1 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EOO04146.1 - 3.3e-06 27.1 0.3 4.3e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal FCH PF00611.18 EOO04148.1 - 1e-22 80.0 6.6 1.7e-22 79.3 0.0 3.3 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EOO04148.1 - 9.9e-21 73.0 0.3 3.5e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EOO04148.1 - 4.9e-15 54.9 5.1 7.6e-15 54.3 3.5 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EOO04148.1 - 2.5e-13 49.1 0.1 3.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EOO04148.1 - 0.0011 18.4 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EOO04148.1 - 0.0023 18.0 0.5 0.072 13.2 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.6 EOO04148.1 - 0.053 12.8 4.8 0.31 10.2 0.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3327 PF11806.3 EOO04148.1 - 0.12 12.7 1.7 0.26 11.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3327) DUF3287 PF11690.3 EOO04148.1 - 0.28 11.2 4.0 4.8 7.2 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) C1_2 PF03107.11 EOO04148.1 - 0.55 10.3 7.8 0.97 9.6 5.4 1.4 1 0 0 1 1 1 0 C1 domain CCDC155 PF14662.1 EOO04148.1 - 0.82 9.2 14.3 0.046 13.3 4.7 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Tup_N PF08581.5 EOO04148.1 - 7.5 6.8 17.1 3.1 8.0 4.9 3.7 2 1 2 4 4 4 0 Tup N-terminal Coatomer_E PF04733.9 EOO04150.1 - 2.5e-63 213.9 4.1 2.9e-63 213.7 2.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EOO04150.1 - 3.2e-08 33.7 18.3 0.004 17.4 0.5 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EOO04150.1 - 3.4e-07 30.7 9.6 7.3e-05 23.3 0.1 4.6 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EOO04150.1 - 8.8e-07 28.2 1.4 0.014 14.4 1.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EOO04150.1 - 1.3e-06 28.3 0.7 0.59 10.3 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EOO04150.1 - 2.8e-06 26.8 1.2 0.013 15.1 0.0 4.0 4 1 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EOO04150.1 - 1.4e-05 25.2 13.6 0.001 19.5 0.6 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 EOO04150.1 - 0.00044 20.3 3.5 0.038 14.0 0.0 3.6 1 1 3 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_1 PF00515.23 EOO04150.1 - 0.0017 17.8 2.1 0.19 11.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EOO04150.1 - 0.0031 17.8 2.1 0.78 10.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EOO04150.1 - 0.0042 16.9 2.0 9.2 6.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EOO04150.1 - 0.0075 16.1 12.9 0.0088 15.8 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EOO04150.1 - 0.012 15.7 0.0 26 5.3 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EOO04150.1 - 0.013 15.2 0.3 0.51 10.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EOO04150.1 - 0.025 14.4 8.8 0.58 10.1 0.4 4.2 2 2 2 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EOO04150.1 - 0.026 14.9 2.5 0.11 12.9 0.5 5.0 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EOO04150.1 - 0.1 12.7 3.3 3.6 7.7 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EOO04150.1 - 0.11 12.3 4.0 1.7 8.5 0.1 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc5 PF12862.2 EOO04150.1 - 0.24 11.2 2.3 53 3.7 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.1 EOO04150.1 - 0.46 10.4 3.7 11 6.1 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.19 EOO04151.1 - 4.1e-18 65.2 0.0 9e-18 64.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EOO04151.1 - 3.5e-07 29.6 0.1 9.2e-07 28.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Transp_cyt_pur PF02133.10 EOO04154.1 - 1.4e-88 297.3 34.7 1.7e-88 297.0 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DEAD PF00270.24 EOO04155.1 - 7.3e-32 110.1 0.1 1.7e-31 108.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO04155.1 - 1.4e-22 79.3 0.0 2.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO04155.1 - 0.00083 19.2 0.0 0.0096 15.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EOO04155.1 - 0.0043 16.6 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EOO04155.1 - 0.0053 16.4 0.3 0.018 14.7 0.1 2.0 1 1 1 2 2 2 1 Part of AAA domain DUF2999 PF11212.3 EOO04155.1 - 0.0094 15.9 0.1 0.031 14.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2999) CMS1 PF14617.1 EOO04155.1 - 0.028 13.4 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EOO04155.1 - 0.076 13.1 1.3 2.9 8.0 0.7 3.0 2 1 0 2 2 2 0 AAA domain Claudin_2 PF13903.1 EOO04156.1 - 8.7e-06 25.5 4.3 0.00025 20.7 0.1 2.0 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.11 EOO04156.1 - 0.24 10.0 9.9 0.59 8.7 6.8 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily Fzo_mitofusin PF04799.8 EOO04156.1 - 0.69 9.2 2.2 0.97 8.7 1.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region CDC50 PF03381.10 EOO04157.1 - 4.5e-98 327.8 0.6 5.6e-98 327.5 0.4 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sirohm_synth_C PF14823.1 EOO04158.1 - 0.064 12.5 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_72 PF03198.9 EOO04159.1 - 6.4e-122 406.4 5.0 7.5e-122 406.2 3.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EOO04159.1 - 2e-08 33.8 1.3 2.3e-07 30.3 0.9 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.3 EOO04159.1 - 0.056 12.6 0.1 0.091 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) BCAS2 PF05700.6 EOO04161.1 - 5.5e-40 137.1 0.0 5.9e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 EOO04161.1 - 0.091 12.5 1.2 0.15 11.8 0.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.24 EOO04162.1 - 3.1e-39 132.6 0.0 1.5e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_23 PF13489.1 EOO04163.1 - 4.3e-07 29.7 0.0 7.4e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EOO04163.1 - 5.6e-05 23.5 0.0 0.00047 20.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO04163.1 - 0.0015 18.9 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pectate_lyase_3 PF12708.2 EOO04164.1 - 6.2e-44 150.7 26.5 9e-38 130.6 6.7 3.4 3 1 0 3 3 3 2 Pectate lyase superfamily protein HAD PF12710.2 EOO04165.1 - 2.4e-10 40.9 0.1 4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EOO04165.1 - 0.0051 16.0 0.0 0.027 13.6 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EOO04165.1 - 0.0066 16.8 0.1 0.035 14.5 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Birna_RdRp PF04197.7 EOO04165.1 - 0.13 10.2 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) UMPH-1 PF05822.7 EOO04165.1 - 0.15 11.3 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Aldedh PF00171.17 EOO04166.1 - 9.3e-110 367.0 0.2 1e-109 366.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EOO04166.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase EamA PF00892.15 EOO04167.1 - 2.8e-11 43.5 29.2 2.4e-06 27.6 0.6 2.6 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EOO04167.1 - 1.5e-06 28.3 0.7 1.5e-06 28.3 0.5 2.8 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EOO04167.1 - 0.0051 16.4 18.6 0.025 14.2 5.7 3.0 3 1 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EOO04167.1 - 0.026 13.6 2.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Cu_amine_oxid PF01179.15 EOO04168.1 - 2.3e-133 444.9 0.1 2.7e-132 441.3 0.0 1.9 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EOO04168.1 - 1.2e-11 44.4 0.0 4.2e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain ODC_AZ PF02100.12 EOO04169.1 - 5.3e-26 90.2 0.0 6.9e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Oxidored_FMN PF00724.15 EOO04171.1 - 5.8e-45 153.7 0.0 7.8e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EOO04171.1 - 0.0089 14.8 0.0 0.031 13.0 0.0 1.8 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) HTH_7 PF02796.10 EOO04171.1 - 0.016 15.0 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Ribosomal_S24e PF01282.14 EOO04172.1 - 4.8e-36 122.4 0.0 7.8e-36 121.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EOO04172.1 - 0.032 13.6 1.0 0.037 13.4 0.7 1.2 1 0 0 1 1 1 0 RRXRR protein FAD_binding_3 PF01494.14 EOO04173.1 - 6e-15 55.1 1.6 2.8e-08 33.2 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EOO04173.1 - 1.4e-10 40.6 0.9 1.5e-06 27.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO04173.1 - 5.1e-09 36.3 0.0 8.4e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EOO04173.1 - 5.9e-08 31.5 0.6 2.6e-05 22.8 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EOO04173.1 - 1.4e-07 30.6 0.5 4e-07 29.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EOO04173.1 - 8.9e-07 28.3 0.4 1.6e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EOO04173.1 - 2.9e-06 27.2 0.1 9.1e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EOO04173.1 - 3.1e-06 26.2 0.1 2.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EOO04173.1 - 2.7e-05 24.4 0.6 0.0056 17.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EOO04173.1 - 4.4e-05 22.2 0.3 0.16 10.5 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EOO04173.1 - 0.00039 19.4 0.3 0.053 12.4 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EOO04173.1 - 0.0039 17.2 0.2 0.0099 15.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO04173.1 - 0.0094 15.0 0.3 0.021 13.9 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EOO04173.1 - 0.029 13.4 0.0 8.1 5.3 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EOO04173.1 - 0.047 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EOO04173.1 - 0.048 13.4 0.5 12 5.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EOO04173.1 - 0.06 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC2_membrane PF01061.19 EOO04175.1 - 8.2e-95 315.8 45.2 8.9e-52 175.3 11.8 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EOO04175.1 - 8.8e-24 84.3 0.0 3e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EOO04175.1 - 8.5e-08 31.5 41.7 2.8e-05 23.3 11.7 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 EOO04175.1 - 0.00067 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EOO04175.1 - 0.0012 18.9 0.0 0.0041 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EOO04175.1 - 0.0018 18.3 0.3 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EOO04175.1 - 0.0067 15.9 0.1 0.021 14.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EOO04175.1 - 0.016 15.1 0.1 1.1 9.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 EOO04175.1 - 0.021 14.2 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EOO04175.1 - 0.074 12.2 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EOO04175.1 - 0.11 12.4 0.4 0.21 11.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EOO04175.1 - 0.11 11.8 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EOO04175.1 - 0.11 12.3 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EOO04175.1 - 0.24 11.2 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1325 PF07039.6 EOO04176.1 - 4.9e-27 94.1 0.0 7.6e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain HDV_ag PF01517.13 EOO04176.1 - 0.0035 17.0 1.0 0.0075 15.9 0.7 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen adh_short PF00106.20 EOO04177.1 - 4.9e-27 94.8 0.0 6.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EOO04177.1 - 6.5e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EOO04177.1 - 4.2e-09 36.5 0.0 5.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EOO04177.1 - 4.2e-05 23.6 0.1 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EOO04177.1 - 7.9e-05 21.9 0.3 0.00011 21.4 0.2 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 EOO04177.1 - 0.0016 18.7 0.0 0.0045 17.3 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EOO04177.1 - 0.0031 16.9 0.0 0.007 15.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EOO04177.1 - 0.0045 16.0 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EOO04177.1 - 0.058 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EOO04177.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Peptidase_M20 PF01546.23 EOO04178.1 - 2.2e-33 115.3 0.0 4.1e-33 114.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EOO04178.1 - 3.8e-14 52.3 0.0 7.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.20 EOO04179.1 - 1.2e-71 240.8 0.0 1.5e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04179.1 - 2.8e-31 108.5 0.0 3.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EOO04179.1 - 0.02 14.6 0.1 0.069 12.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EOO04179.1 - 0.089 11.8 0.1 0.25 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.14 EOO04180.1 - 9.3e-118 393.0 0.0 1.1e-117 392.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EOO04180.1 - 0.027 13.0 0.0 0.19 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein DUF3455 PF11937.3 EOO04182.1 - 1.8e-32 112.7 0.0 3.6e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Response_reg PF00072.19 EOO04183.1 - 1.4e-25 89.4 0.2 2.7e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EOO04183.1 - 2.9e-25 88.1 0.0 5.6e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EOO04183.1 - 1.6e-18 66.4 0.1 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EOO04183.1 - 1.9e-15 57.1 0.0 4.8e-14 52.5 0.0 2.6 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 EOO04183.1 - 1e-07 31.7 0.0 1.6e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EOO04183.1 - 1.6e-06 28.1 0.0 0.0066 16.4 0.0 2.7 3 0 0 3 3 3 2 PAS fold FR47 PF08445.5 EOO04183.1 - 0.043 13.5 0.3 3.7 7.3 0.1 2.6 2 0 0 2 2 2 0 FR47-like protein NDUF_B7 PF05676.8 EOO04184.1 - 2.3e-32 110.1 3.4 3e-32 109.8 2.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EOO04184.1 - 0.019 14.7 2.0 0.025 14.3 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 EOO04184.1 - 1.8 8.8 6.2 1.2 9.3 2.4 1.9 1 1 1 2 2 2 0 Antifungal protein AA_permease PF00324.16 EOO04185.1 - 5.1e-118 394.4 40.6 6.2e-118 394.1 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EOO04185.1 - 5.3e-32 110.8 46.2 7.1e-32 110.4 32.0 1.2 1 0 0 1 1 1 1 Amino acid permease Hexapep PF00132.19 EOO04186.1 - 6.2e-07 28.6 9.5 5.3e-05 22.5 1.6 4.1 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EOO04186.1 - 0.00074 19.0 4.0 0.0066 15.9 0.2 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NPP1 PF05630.6 EOO04187.1 - 2.2e-62 210.4 0.0 2.6e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) 4HBT_2 PF13279.1 EOO04188.1 - 0.0045 17.4 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily PMC2NT PF08066.7 EOO04188.1 - 0.041 14.1 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Voltage_CLC PF00654.15 EOO04189.1 - 2.5e-89 299.7 12.5 3.3e-89 299.3 8.7 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EOO04189.1 - 0.003 17.3 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 CBS domain Amidase PF01425.16 EOO04190.1 - 8e-81 272.1 0.0 9.1e-81 271.9 0.0 1.0 1 0 0 1 1 1 1 Amidase zf-HC2 PF13490.1 EOO04190.1 - 0.039 13.8 0.2 0.14 12.1 0.0 1.9 1 1 1 2 2 2 0 Putative zinc-finger Glyco_hydro_3 PF00933.16 EOO04191.1 - 1.2e-75 254.2 0.0 1.8e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EOO04191.1 - 4.5e-47 160.4 0.0 9.4e-47 159.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO04191.1 - 2e-15 56.4 0.2 7.6e-15 54.6 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EOO04191.1 - 4.4e-11 42.6 0.5 1.3e-10 41.1 0.3 1.7 1 0 0 1 1 1 1 PA14 domain DUF221 PF02714.10 EOO04192.1 - 9.5e-44 149.5 4.2 1.8e-43 148.6 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EOO04192.1 - 6.1e-27 93.3 0.4 1e-26 92.6 0.3 1.3 1 0 0 1 1 1 1 Phosphate metabolism protein Claudin_2 PF13903.1 EOO04192.1 - 5.2 6.7 7.3 0.46 10.1 0.2 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PIRT PF15099.1 EOO04194.1 - 0.55 9.4 1.8 0.48 9.6 0.2 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Colicin_V PF02674.11 EOO04194.1 - 2.9 7.7 9.3 11 5.8 0.1 3.5 3 2 0 3 3 3 0 Colicin V production protein Aldo_ket_red PF00248.16 EOO04195.1 - 7.6e-37 126.6 0.0 1.1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EOO04196.1 - 1.4e-28 99.7 0.1 1.9e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO04196.1 - 6.7e-18 65.3 1.2 7.5e-18 65.1 0.2 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EOO04196.1 - 0.00022 20.7 0.3 0.00096 18.6 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO04196.1 - 0.00023 20.1 1.1 0.00047 19.1 0.8 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EOO04196.1 - 0.018 13.9 0.0 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein PrpR_N PF06506.6 EOO04196.1 - 0.22 10.9 5.7 0.075 12.4 1.1 2.3 3 1 0 3 3 3 0 Propionate catabolism activator ATP-synt_Eps PF04627.8 EOO04196.1 - 1 8.9 3.9 4.8 6.8 0.9 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain Peptidase_M28 PF04389.12 EOO04197.1 - 3e-34 118.3 0.0 4.9e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EOO04197.1 - 2.3e-11 43.2 0.0 7.1e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EOO04197.1 - 0.00057 19.4 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EOO04198.1 - 2.2e-14 52.9 19.2 2.9e-14 52.5 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EOO04198.1 - 8.3e-11 41.1 10.2 1.1e-09 37.4 7.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter M20_dimer PF07687.9 EOO04199.1 - 2.2e-07 30.5 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EOO04199.1 - 0.00019 21.0 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Arf PF00025.16 EOO04200.1 - 2.9e-65 218.7 0.5 3.4e-65 218.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EOO04200.1 - 2.8e-13 49.5 0.1 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EOO04200.1 - 9.9e-13 47.5 1.9 2.2e-09 36.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EOO04200.1 - 9e-12 44.5 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EOO04200.1 - 1e-11 44.4 0.1 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EOO04200.1 - 3.9e-08 33.8 0.0 5.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EOO04200.1 - 0.00028 20.8 0.0 0.00049 20.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EOO04200.1 - 0.048 12.7 0.2 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase GTP_cyclohydro2 PF00925.15 EOO04201.1 - 1.7e-57 193.3 0.0 6.7e-53 178.3 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II NmrA PF05368.8 EOO04202.1 - 3.9e-29 101.5 0.0 4.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO04202.1 - 7.5e-18 65.1 0.0 1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EOO04202.1 - 0.0095 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SHS2_Rpb7-N PF03876.12 EOO04203.1 - 1.6e-06 28.0 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 His_biosynth PF00977.16 EOO04204.1 - 1.2e-48 165.3 0.2 6.5e-48 162.9 0.2 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EOO04204.1 - 2.3e-26 92.4 0.0 3.6e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EOO04204.1 - 4.2e-11 42.8 0.0 4.4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EOO04204.1 - 6.1e-07 29.1 0.0 1.3e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EOO04204.1 - 0.081 12.3 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.12 EOO04204.1 - 0.12 11.1 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) AA_permease_2 PF13520.1 EOO04205.1 - 8.6e-22 77.2 25.0 9.6e-22 77.0 17.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EOO04205.1 - 2e-07 29.7 16.0 2.2e-07 29.5 11.1 1.1 1 0 0 1 1 1 1 Amino acid permease TrbL PF04610.9 EOO04205.1 - 0.24 11.0 13.4 0.2 11.2 8.1 1.7 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2754 PF10953.3 EOO04205.1 - 1.3 9.0 5.7 0.67 10.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Sugar_tr PF00083.19 EOO04206.1 - 3.2e-83 279.7 27.4 3e-82 276.5 19.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04206.1 - 7.7e-26 90.6 39.6 7.8e-26 90.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EOO04207.1 - 6.2e-10 38.7 0.0 2.1e-09 37.1 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EOO04207.1 - 1.8e-09 38.5 0.0 4.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EOO04207.1 - 9e-09 34.9 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PMI_typeI PF01238.16 EOO04208.1 - 5.3e-134 446.8 0.0 6.2e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EOO04208.1 - 0.091 12.2 0.1 4.7 6.7 0.1 2.5 2 1 0 2 2 2 0 Cupin domain Pkinase PF00069.20 EOO04209.1 - 1.4e-61 207.9 0.0 1.8e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04209.1 - 6.4e-31 107.3 0.0 1.1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04209.1 - 0.0027 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EOO04209.1 - 0.025 14.3 0.0 0.21 11.2 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family CFEM PF05730.6 EOO04210.1 - 1.9e-12 46.7 14.1 2.8e-12 46.2 9.8 1.2 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.6 EOO04210.1 - 0.53 8.0 6.5 0.52 8.1 4.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NmrA PF05368.8 EOO04211.1 - 6e-32 110.7 0.1 7.5e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EOO04211.1 - 1.5e-11 44.6 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO04211.1 - 0.00031 20.2 0.0 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EOO04211.1 - 0.00069 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EOO04211.1 - 0.0034 17.2 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EOO04211.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EOO04211.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LMWPc PF01451.16 EOO04212.1 - 2.7e-35 121.6 0.0 3.1e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1680 PF07944.7 EOO04213.1 - 2.5e-20 72.2 0.0 5.1e-20 71.2 0.0 1.4 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Yippee-Mis18 PF03226.9 EOO04214.1 - 4.2e-19 68.3 0.0 6.6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EOO04214.1 - 0.0012 18.7 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I Ribosomal_60s PF00428.14 EOO04214.1 - 4.8 7.6 6.8 5.4 7.4 0.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.11 EOO04215.1 - 1.3e-08 34.0 27.0 3e-08 32.7 18.7 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3902 PF13042.1 EOO04215.1 - 1.3 8.3 9.1 0.13 11.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) ICL PF00463.16 EOO04216.1 - 1.3e-121 406.4 0.3 1.6e-121 406.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EOO04216.1 - 6.9e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ank_2 PF12796.2 EOO04217.1 - 5.9e-16 58.5 0.7 1.6e-05 25.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EOO04217.1 - 7.2e-16 57.1 0.1 5.5e-07 29.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EOO04217.1 - 4.1e-12 45.9 0.9 9.6e-06 25.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EOO04217.1 - 8.4e-11 42.0 0.7 0.00041 20.7 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EOO04217.1 - 2.8e-08 33.2 0.4 0.25 11.7 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EOO04217.1 - 1.9e-07 30.6 0.1 1.5e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Mnd1 PF03962.10 EOO04217.1 - 0.012 15.2 2.1 0.29 10.7 1.3 2.4 1 1 0 1 1 1 0 Mnd1 family DUF1635 PF07795.6 EOO04217.1 - 0.017 14.4 1.0 1.4 8.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF1546 PF07571.8 EOO04217.1 - 0.11 12.5 0.1 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) SnAC PF14619.1 EOO04217.1 - 0.58 10.3 5.1 0.14 12.3 0.4 2.3 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Pro_isomerase PF00160.16 EOO04218.1 - 1.9e-24 86.6 0.0 5.2e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EOO04218.1 - 8.9e-15 54.0 0.0 1.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04218.1 - 8.4e-11 41.6 0.1 3.8e-10 39.5 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04218.1 - 6.1e-09 35.5 0.3 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin_7 PF13899.1 EOO04219.1 - 1.3e-14 54.0 0.1 3.8e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EOO04219.1 - 1.7e-12 46.6 0.4 3.9e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 EOO04219.1 - 4.1e-09 36.3 0.0 8.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 EOO04219.1 - 0.0011 18.6 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EOO04219.1 - 0.016 15.4 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain Prothymosin PF03247.9 EOO04219.1 - 2.4 8.3 9.7 0.22 11.6 2.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family FYDLN_acid PF09538.5 EOO04219.1 - 3.6 8.2 11.7 2.8 8.5 4.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Iso_dh PF00180.15 EOO04221.1 - 1.7e-80 270.6 0.0 1.9e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DEAD PF00270.24 EOO04222.1 - 1.8e-43 147.9 0.0 1.4e-40 138.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EOO04222.1 - 3.5e-20 71.6 0.1 1.2e-19 69.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EOO04222.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EOO04222.1 - 0.0023 17.6 0.2 0.012 15.3 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EOO04222.1 - 0.019 14.5 0.0 2.2 7.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EOO04222.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SecA_DEAD PF07517.9 EOO04222.1 - 0.095 11.9 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_22 PF13401.1 EOO04222.1 - 0.16 12.1 0.7 0.93 9.6 0.5 2.2 2 1 0 2 2 2 0 AAA domain Tyrosinase PF00264.15 EOO04223.1 - 1.8e-47 162.3 1.1 2.4e-47 161.9 0.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase WBS_methylT PF12589.3 EOO04224.1 - 7.7e-17 61.5 4.3 1.5e-16 60.6 3.0 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EOO04224.1 - 9.3e-12 45.2 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EOO04224.1 - 6e-08 32.9 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EOO04224.1 - 2e-06 27.4 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EOO04224.1 - 3.8e-05 24.0 0.0 0.00011 22.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EOO04224.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EOO04224.1 - 0.0002 21.3 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EOO04224.1 - 0.00022 21.7 0.0 0.00051 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EOO04224.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EOO04224.1 - 0.056 12.5 0.0 0.3 10.1 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EOO04224.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EOO04225.1 - 3.3e-07 30.4 0.2 5.1e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EOO04226.1 - 1.4e-10 40.3 6.2 1.4e-10 40.3 4.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1405 PF07187.6 EOO04226.1 - 0.03 14.0 0.9 0.042 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) G3P_acyltransf PF02660.10 EOO04226.1 - 0.13 11.7 4.8 0.026 14.0 1.2 1.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase MFS_1 PF07690.11 EOO04228.1 - 8.8e-08 31.2 1.4 1e-07 31.0 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF997 PF06196.7 EOO04228.1 - 0.049 13.1 0.7 3.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF997) DPBB_1 PF03330.13 EOO04229.1 - 2.6e-09 36.9 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel adh_short PF00106.20 EOO04230.1 - 6.6e-09 35.9 0.0 3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 EOO04230.1 - 0.00029 20.0 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EOO04230.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO04230.1 - 0.024 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain ADH_zinc_N PF00107.21 EOO04231.1 - 3.9e-25 87.8 0.8 5.7e-25 87.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EOO04231.1 - 0.0082 16.1 2.0 0.019 14.9 1.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EOO04231.1 - 0.18 11.2 0.8 0.29 10.5 0.5 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FTCD_C PF04961.7 EOO04231.1 - 0.27 10.6 3.3 0.22 10.9 1.4 1.5 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Alpha-amylase PF00128.19 EOO04232.1 - 7.2e-20 71.6 0.0 2.2e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Pkinase PF00069.20 EOO04234.1 - 6.8e-70 235.1 0.0 1.7e-69 233.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04234.1 - 2.8e-50 170.8 0.0 5e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04234.1 - 0.0022 16.9 0.0 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Ecm29 PF13001.2 EOO04235.1 - 1.6e-118 396.3 0.0 6.6e-118 394.3 0.0 2.1 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 EOO04235.1 - 0.0011 18.9 6.5 1.2 9.4 0.0 6.4 8 0 0 8 8 8 2 HEAT repeat DUF4042 PF13251.1 EOO04235.1 - 0.0032 16.9 0.0 0.18 11.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.1 EOO04235.1 - 0.025 15.0 6.8 0.095 13.2 0.0 5.6 6 0 0 6 6 6 0 HEAT-like repeat Abhydrolase_3 PF07859.8 EOO04236.1 - 2.1e-41 141.8 0.0 4.6e-41 140.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EOO04236.1 - 9.9e-06 24.4 0.0 3.7e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EOO04236.1 - 0.00071 19.3 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EOO04236.1 - 0.0021 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 EOO04236.1 - 0.0033 16.2 0.7 0.013 14.2 0.5 1.8 1 1 0 1 1 1 1 Carboxylesterase family LIP PF03583.9 EOO04236.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Lipase_GDSL PF00657.17 EOO04237.1 - 8.9e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.17 EOO04238.1 - 2.7e-48 161.4 0.0 1.4e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04238.1 - 3.8e-25 87.6 0.0 5.7e-10 39.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04238.1 - 6.8e-21 73.8 0.0 1.2e-08 34.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EOO04238.1 - 2e-05 24.3 0.0 0.00014 21.6 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EOO04238.1 - 5.2e-05 22.9 0.1 0.0032 17.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF4455 PF14643.1 EOO04239.1 - 0.024 13.2 0.1 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Seryl_tRNA_N PF02403.17 EOO04239.1 - 1.3 9.0 8.0 0.14 12.1 1.8 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glyoxalase PF00903.20 EOO04240.1 - 2.5e-11 43.6 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EOO04240.1 - 1.2e-10 41.9 0.0 1.6e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EOO04240.1 - 5.6e-09 35.9 0.0 7.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EOO04240.1 - 0.0086 16.0 0.0 0.12 12.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Dabb PF07876.7 EOO04243.1 - 6.8e-16 58.4 0.0 8.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3292 PF11696.3 EOO04244.1 - 2.7e-230 765.6 0.0 3.4e-230 765.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) MFS_1 PF07690.11 EOO04245.1 - 1.7e-42 145.4 58.4 2.7e-42 144.7 36.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EOO04245.1 - 3.6e-12 45.2 19.3 4.8e-12 44.8 13.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EOO04245.1 - 4.1e-06 25.6 13.6 4.1e-06 25.6 9.4 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter VCBS PF13517.1 EOO04246.1 - 1.6e-31 108.4 49.5 9.9e-13 48.2 0.8 8.7 4 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EOO04246.1 - 7.2e-14 50.9 43.3 0.0015 18.1 0.5 9.7 10 0 0 10 10 10 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EOO04246.1 - 4.2e-09 36.0 15.2 0.28 10.6 0.1 7.1 3 2 3 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 EOO04246.1 - 5.3e-09 36.4 0.1 1.2e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EOO04246.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_3 PF01494.14 EOO04247.1 - 3e-12 46.2 0.0 3.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Carbpep_Y_N PF05388.6 EOO04249.1 - 0.0073 16.4 0.2 2.5 8.3 0.0 2.8 1 1 1 2 2 2 1 Carboxypeptidase Y pro-peptide EspB PF05802.6 EOO04249.1 - 0.014 14.3 1.1 0.026 13.4 0.7 1.4 1 1 0 1 1 1 0 Enterobacterial EspB protein ATG_C PF09333.6 EOO04249.1 - 0.019 15.1 0.7 0.43 10.7 0.5 3.0 1 1 0 1 1 1 0 ATG C terminal domain DUF883 PF05957.8 EOO04249.1 - 0.028 14.7 0.2 2 8.8 0.0 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 EOO04249.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) GvpL_GvpF PF06386.6 EOO04249.1 - 0.075 12.6 0.1 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ISG65-75 PF11727.3 EOO04249.1 - 0.094 11.7 1.2 0.11 11.5 0.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein YtxH PF12732.2 EOO04249.1 - 0.12 12.7 2.1 2.6 8.4 0.8 2.7 1 1 1 2 2 2 0 YtxH-like protein Tape_meas_lam_C PF09718.5 EOO04249.1 - 0.16 11.8 1.2 12 5.9 0.0 2.4 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Chlorosome_CsmC PF11098.3 EOO04249.1 - 0.22 11.2 4.7 0.37 10.4 2.7 1.7 1 1 0 1 1 1 0 Chlorosome envelope protein C FIVAR PF07554.8 EOO04249.1 - 0.38 11.0 5.4 2.2 8.6 0.1 3.5 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Zip PF02535.17 EOO04251.1 - 7 5.5 8.4 12 4.8 5.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter adh_short PF00106.20 EOO04252.1 - 5.1e-28 98.0 1.4 8.9e-28 97.2 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO04252.1 - 2.5e-12 47.0 0.1 3.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO04252.1 - 2.9e-10 40.0 3.4 2.4e-09 37.1 2.4 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO04252.1 - 0.018 14.5 0.2 0.024 14.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO04252.1 - 0.038 13.9 0.2 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding Alkyl_sulf_dimr PF14863.1 EOO04252.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation DUF1227 PF06777.6 EOO04253.1 - 7e-62 207.4 1.2 1e-61 206.8 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EOO04253.1 - 1.5e-44 151.9 0.1 5.6e-44 150.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EOO04253.1 - 3.3e-17 62.4 0.9 3.3e-17 62.4 0.6 1.7 2 0 0 2 2 2 1 DEAD_2 ORC5_C PF14630.1 EOO04254.1 - 4.1e-78 262.5 0.0 5.8e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EOO04254.1 - 1.1e-17 64.6 0.1 2.4e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EOO04254.1 - 0.0085 16.2 0.0 0.025 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EOO04254.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 EOO04254.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) WD40 PF00400.27 EOO04255.1 - 1.3e-46 154.8 17.5 5.7e-13 48.2 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EOO04255.1 - 0.00025 20.4 0.2 18 4.9 0.0 5.0 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EOO04255.1 - 0.2 10.4 1.0 0.5 9.1 0.3 1.7 2 0 0 2 2 2 0 Coatomer WD associated region PUF PF00806.14 EOO04256.1 - 1.7e-37 124.8 0.6 3.7e-06 26.1 0.0 9.2 10 0 0 10 10 10 8 Pumilio-family RNA binding repeat Cpn60_TCP1 PF00118.19 EOO04257.1 - 2.3e-118 395.9 8.6 2.6e-118 395.7 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nramp PF01566.13 EOO04259.1 - 6e-73 245.6 15.2 6e-73 245.6 10.5 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Pkinase PF00069.20 EOO04260.1 - 3.5e-12 46.0 0.0 1.4e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04260.1 - 5.2e-05 22.4 0.0 0.00095 18.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Alpha-L-AF_C PF06964.7 EOO04261.1 - 1.1e-32 113.2 0.0 1.8e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sds3 PF08598.6 EOO04263.1 - 5.9e-49 166.3 5.8 1.2e-48 165.4 4.0 1.6 1 1 0 1 1 1 1 Sds3-like AntA PF08346.7 EOO04263.1 - 0.045 13.9 0.2 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 AntA/AntB antirepressor Alpha-amylase_C PF02806.13 EOO04264.1 - 1.6e-24 85.8 0.0 4.4e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EOO04264.1 - 2e-18 66.8 0.0 5.4e-15 55.6 0.0 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EOO04264.1 - 1.1e-07 31.8 0.0 1.3e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 EOO04264.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 EOO04264.1 - 0.17 10.7 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Mob1_phocein PF03637.12 EOO04265.1 - 1.6e-69 233.0 0.0 2.2e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.15 EOO04266.1 - 3.4e-05 23.4 0.0 0.021 14.4 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Aldo_ket_red PF00248.16 EOO04267.1 - 3.5e-42 144.1 0.0 4.1e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4595 PF15283.1 EOO04268.1 - 0.1 12.2 0.3 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold Med3 PF11593.3 EOO04269.1 - 0.013 14.7 3.8 0.017 14.4 2.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GET2 PF08690.5 EOO04269.1 - 0.51 9.5 3.3 0.78 8.9 2.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 OSCP PF00213.13 EOO04270.1 - 3.5e-45 153.9 0.2 4.2e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 EOO04271.1 - 1.4e-07 29.7 1.0 3.5e-05 21.8 0.0 2.9 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Hep_59 PF07052.6 EOO04271.1 - 0.082 13.2 1.5 0.23 11.8 1.0 1.7 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Auxin_repressed PF05564.7 EOO04272.1 - 0.041 14.4 1.8 0.073 13.6 1.3 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein SpoVIF PF14069.1 EOO04272.1 - 0.079 12.7 0.0 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF382 PF04037.8 EOO04273.1 - 1e-61 206.4 0.7 1e-61 206.4 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EOO04273.1 - 9.5e-22 76.1 4.1 2e-21 75.0 2.9 1.6 1 0 0 1 1 1 1 PSP CENP-B_dimeris PF09026.5 EOO04273.1 - 6.3 7.1 17.5 0.041 14.1 4.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TIP49 PF06068.8 EOO04275.1 - 1.1e-175 584.1 3.5 1.3e-175 583.8 2.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EOO04275.1 - 1.6e-08 33.8 2.4 5.7e-05 22.2 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EOO04275.1 - 6.6e-08 32.8 1.2 8.4e-05 22.7 0.0 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EOO04275.1 - 5.5e-06 25.4 0.4 8.9e-06 24.7 0.3 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EOO04275.1 - 0.00015 21.9 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EOO04275.1 - 0.00029 20.8 0.0 0.0034 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EOO04275.1 - 0.0005 19.2 0.7 0.012 14.7 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EOO04275.1 - 0.0011 18.8 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EOO04275.1 - 0.011 15.2 0.1 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EOO04275.1 - 0.017 14.8 0.1 2.4 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EOO04275.1 - 0.023 14.1 0.1 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EOO04275.1 - 0.029 14.0 0.1 0.083 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EOO04275.1 - 0.074 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EOO04275.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EOO04275.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain MRP-S33 PF08293.6 EOO04276.1 - 1.8e-33 114.3 0.1 2.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 ScpA_ScpB PF02616.9 EOO04276.1 - 0.062 12.8 0.1 0.069 12.7 0.1 1.1 1 0 0 1 1 1 0 ScpA/B protein UFD1 PF03152.9 EOO04277.1 - 1.5e-58 196.8 0.0 1.9e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EOO04277.1 - 0.022 14.3 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Histone PF00125.19 EOO04279.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EOO04279.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EOO04279.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EOO04279.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DAO PF01266.19 EOO04280.1 - 2.4e-50 171.4 0.0 3.5e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EOO04280.1 - 3.2e-08 32.8 0.2 9.2e-08 31.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EOO04280.1 - 9.8e-06 24.8 3.2 0.00013 21.1 2.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EOO04280.1 - 0.00018 21.4 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EOO04280.1 - 0.00029 20.0 0.8 0.018 14.1 0.2 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EOO04280.1 - 0.0013 18.7 0.1 0.0058 16.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EOO04280.1 - 0.0032 17.1 0.1 0.0067 16.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EOO04280.1 - 0.013 13.9 0.4 0.02 13.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EOO04280.1 - 0.021 15.2 0.3 0.051 13.9 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EOO04280.1 - 0.024 13.5 0.1 0.11 11.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EOO04280.1 - 0.037 13.0 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EOO04280.1 - 0.039 14.0 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EOO04280.1 - 0.04 12.8 0.0 0.24 10.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EOO04280.1 - 0.044 13.8 0.2 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PCI PF01399.22 EOO04282.1 - 1.2e-20 73.7 0.2 5.5e-20 71.6 0.1 2.2 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.1 EOO04282.1 - 6.2e-06 25.6 4.6 4 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EOO04282.1 - 7.2e-05 22.2 3.9 0.72 9.8 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 EOO04282.1 - 0.00014 21.2 0.5 0.00025 20.5 0.3 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_16 PF13432.1 EOO04282.1 - 0.0021 18.6 10.1 1.2 9.8 0.5 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EOO04282.1 - 0.0094 15.7 5.4 7.3 6.7 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EOO04282.1 - 0.04 13.6 2.4 0.052 13.3 0.8 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_4 PF07721.9 EOO04282.1 - 0.091 13.2 0.3 0.51 10.9 0.1 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat Med2 PF11214.3 EOO04282.1 - 0.11 12.5 2.9 0.16 12.0 0.0 2.7 3 1 0 3 3 3 0 Mediator complex subunit 2 TPR_12 PF13424.1 EOO04282.1 - 0.14 12.0 17.6 0.22 11.4 0.7 5.0 2 1 2 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EOO04282.1 - 0.15 11.6 6.5 16 5.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EOO04282.1 - 0.38 11.5 9.8 17 6.3 0.1 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat MetRS-N PF09635.5 EOO04282.1 - 0.45 10.9 4.8 1.8 8.9 0.4 3.1 2 1 1 3 3 3 0 MetRS-N binding domain F-box-like PF12937.2 EOO04283.1 - 0.007 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Phe_hydrox_dim PF07976.7 EOO04284.1 - 1.8e-43 148.0 0.0 2.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 EOO04284.1 - 8.9e-26 90.7 0.2 1.9e-25 89.7 0.1 1.5 1 1 1 2 2 2 1 FAD binding domain Nol1_Nop2_Fmu PF01189.12 EOO04285.1 - 2.3e-98 329.0 0.0 4.5e-98 328.1 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family Toprim_Crpt PF13342.1 EOO04285.1 - 0.0072 15.9 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase Methyltransf_31 PF13847.1 EOO04285.1 - 0.018 14.5 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EOO04285.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.12 EOO04285.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin ATP-synt_ab PF00006.20 EOO04286.1 - 9.6e-62 208.2 0.0 1.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EOO04286.1 - 1.1e-25 90.3 0.4 2e-25 89.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EOO04286.1 - 5.7e-25 87.3 0.7 2.8e-24 85.1 0.2 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 EOO04286.1 - 0.006 16.3 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EOO04286.1 - 0.012 15.0 0.5 0.057 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EOO04286.1 - 0.015 15.4 0.1 0.62 10.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EOO04286.1 - 0.016 14.3 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EOO04286.1 - 0.019 14.6 0.1 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EOO04286.1 - 0.024 13.7 0.1 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EOO04286.1 - 0.024 14.2 0.1 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EOO04286.1 - 0.033 14.1 0.4 0.24 11.3 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EOO04286.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EOO04286.1 - 0.07 13.2 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EOO04286.1 - 0.081 11.7 0.7 0.63 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Blt1 PF12754.2 EOO04287.1 - 1.1e-38 133.6 5.6 4.4e-33 115.1 1.7 2.1 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 EOO04287.1 - 4.4e-05 22.7 0.3 7.8e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family XRCC4 PF06632.7 EOO04288.1 - 5.1e-07 28.8 12.0 1.6e-06 27.2 8.3 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 CENP-F_leu_zip PF10473.4 EOO04288.1 - 0.00091 19.0 0.8 0.002 17.9 0.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3585 PF12130.3 EOO04288.1 - 0.0094 15.8 1.2 0.017 14.9 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) FliJ PF02050.11 EOO04288.1 - 0.019 14.9 5.0 0.038 14.0 3.5 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein HR1 PF02185.11 EOO04288.1 - 0.025 14.3 0.4 0.069 12.8 0.3 1.7 1 0 0 1 1 1 0 Hr1 repeat PEP-utilisers_N PF05524.8 EOO04288.1 - 0.028 14.2 4.3 0.1 12.3 2.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal WXG100 PF06013.7 EOO04288.1 - 0.15 12.1 3.2 0.37 10.8 2.2 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Pectate_lyase_3 PF12708.2 EOO04289.1 - 3.9e-58 197.2 26.1 9.6e-46 156.7 3.8 3.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EOO04289.1 - 0.00012 21.4 2.8 0.16 11.4 0.2 3.4 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Adeno_E1B_55K PF01696.12 EOO04289.1 - 0.0086 14.5 0.4 0.014 13.8 0.3 1.2 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen MIP PF00230.15 EOO04291.1 - 2.2e-27 96.0 12.8 2.9e-27 95.6 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.19 EOO04292.1 - 1.3e-93 314.0 17.9 1.9e-93 313.4 12.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04292.1 - 1.2e-27 96.5 21.8 9.3e-20 70.6 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 EOO04292.1 - 0.0054 15.3 1.7 0.0054 15.3 1.2 2.0 1 1 1 2 2 2 1 LacY proton/sugar symporter Lig_chan PF00060.21 EOO04292.1 - 1.6 8.4 4.2 30 4.3 0.2 3.5 3 1 0 3 3 3 0 Ligand-gated ion channel Transket_pyr PF02779.19 EOO04293.1 - 9.2e-65 217.4 0.0 1.6e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EOO04293.1 - 8.9e-56 188.7 0.0 1.3e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PP2C PF00481.16 EOO04294.1 - 2.2e-44 151.7 0.0 3.5e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EOO04294.1 - 8.3e-06 25.6 0.0 0.019 14.6 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EOO04294.1 - 1.3e-05 24.6 0.1 3.6e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SEP PF08059.8 EOO04294.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 SEP domain Glyco_hydro_72 PF03198.9 EOO04295.1 - 7.3e-102 340.5 0.1 2.2e-101 338.9 0.1 1.6 2 0 0 2 2 2 1 Glucanosyltransferase Peptidase_C48 PF02902.14 EOO04296.1 - 4.6e-18 65.6 0.0 1.1e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain COX4 PF02936.9 EOO04297.1 - 4e-50 169.2 0.0 4.7e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ni_hydr_CYTB PF01292.15 EOO04297.1 - 0.026 13.8 0.1 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 WD40 PF00400.27 EOO04300.1 - 2.2e-15 55.8 0.3 0.00012 21.8 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EOO04300.1 - 0.0015 18.2 0.0 1 9.0 0.0 3.5 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Sof1 PF04158.9 EOO04302.1 - 1.2e-30 105.3 18.9 1.7e-30 104.8 13.1 1.2 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EOO04302.1 - 1.1e-18 66.3 0.1 9.5e-09 34.8 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EOO04302.1 - 0.00019 21.2 0.0 0.2 11.4 0.0 2.4 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region tRNA_m1G_MT PF01746.16 EOO04302.1 - 0.021 14.3 0.7 0.032 13.8 0.5 1.3 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase ACBP PF00887.14 EOO04303.1 - 4.7e-32 109.5 0.0 5.3e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EOO04303.1 - 0.14 12.2 0.1 0.75 9.9 0.0 1.9 1 1 0 2 2 2 0 FERM central domain PRP3 PF08572.5 EOO04306.1 - 6.2e-60 202.3 7.5 1.1e-59 201.5 5.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EOO04306.1 - 4.7e-40 136.2 1.9 4.7e-40 136.2 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Myb_DNA-bind_4 PF13837.1 EOO04307.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain LSM PF01423.17 EOO04308.1 - 5.6e-14 51.4 0.0 8.9e-14 50.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain Rep_fac_C PF08542.6 EOO04309.1 - 3.2e-22 78.3 0.0 1.1e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EOO04309.1 - 3.8e-11 42.9 0.0 7.6e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EOO04309.1 - 2e-06 27.9 0.6 0.0001 22.4 0.1 3.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EOO04309.1 - 2.1e-06 27.9 0.0 4.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EOO04309.1 - 8.4e-05 22.6 1.5 0.022 14.7 0.8 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EOO04309.1 - 0.0038 17.1 0.1 0.011 15.6 0.1 1.7 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EOO04309.1 - 0.0098 15.9 0.3 0.4 10.7 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 EOO04309.1 - 0.023 14.9 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.9 EOO04309.1 - 0.028 12.9 0.1 0.13 10.7 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.2 EOO04309.1 - 0.036 13.5 0.2 2.1 7.7 0.0 2.6 2 1 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 EOO04309.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 EOO04309.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) Rad17 PF03215.10 EOO04309.1 - 0.082 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SNF2_N PF00176.18 EOO04309.1 - 0.099 11.4 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Neugrin PF06413.6 EOO04310.1 - 4.6e-13 49.5 1.3 5.2e-13 49.3 0.5 1.5 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EOO04310.1 - 4.2e-07 30.0 3.2 2.1e-06 27.7 2.3 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EOO04310.1 - 0.016 15.3 1.3 0.028 14.5 0.0 2.1 2 1 0 2 2 2 0 Winged helix-turn helix DUF955 PF06114.8 EOO04310.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Herpes_ICP4_C PF03585.9 EOO04310.1 - 0.061 12.0 0.1 0.081 11.6 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region Sigma70_r4 PF04545.11 EOO04310.1 - 0.11 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 UPF0061 PF02696.9 EOO04311.1 - 2.1e-125 418.8 0.0 2.7e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GHL15 PF14885.1 EOO04311.1 - 0.086 13.0 1.5 5.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Hypothetical glycosyl hydrolase family 15 TFIIH_BTF_p62_N PF08567.6 EOO04312.1 - 1.4e-24 85.5 0.0 9.2e-24 82.9 0.0 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EOO04312.1 - 3.5e-24 84.2 2.3 5.5e-13 48.4 0.1 2.7 2 0 0 2 2 2 2 BSD domain Rick_17kDa_Anti PF05433.10 EOO04313.1 - 0.00022 20.8 5.6 0.036 13.7 0.1 2.3 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EOO04313.1 - 0.011 15.2 6.6 0.023 14.1 4.6 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EOO04313.1 - 0.063 12.9 0.5 0.063 12.9 0.4 2.8 2 1 1 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EOO04313.1 - 0.78 9.4 12.0 14 5.4 8.4 2.3 1 1 0 1 1 1 0 Glycine zipper WD40 PF00400.27 EOO04314.1 - 0.00019 21.1 2.7 0.0012 18.6 0.0 3.5 4 1 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.6 EOO04314.1 - 0.082 12.1 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Histone PF00125.19 EOO04316.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EOO04316.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EOO04316.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EOO04316.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EOO04316.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EOO04316.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T VEFS-Box PF09733.4 EOO04317.1 - 7.1e-10 38.6 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Molybdopterin PF00384.17 EOO04318.1 - 1.7e-75 254.4 0.1 1.5e-73 248.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EOO04318.1 - 4.6e-19 67.3 0.1 1.1e-18 66.1 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EOO04318.1 - 9.9e-16 57.6 0.0 2.8e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 EOO04318.1 - 0.00015 21.5 0.1 0.0097 15.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4_19 PF06902.6 EOO04318.1 - 0.075 12.8 1.6 0.7 9.7 1.1 2.4 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 EOO04318.1 - 0.092 12.3 1.1 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EOO04318.1 - 0.38 10.7 3.3 0.4 10.6 0.9 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain AMP-binding PF00501.23 EOO04319.1 - 1.1e-90 304.0 0.2 1.3e-90 303.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO04319.1 - 9.2e-22 77.7 0.5 2e-19 70.3 0.3 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Esterase_phd PF10503.4 EOO04320.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EOO04320.1 - 1.2e-06 27.8 0.6 1.5e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EOO04320.1 - 1.9e-05 24.3 0.1 2.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EOO04320.1 - 0.00019 21.3 0.1 0.00036 20.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EOO04320.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EOO04320.1 - 0.0029 17.0 0.4 0.0034 16.8 0.3 1.2 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 EOO04320.1 - 0.012 15.2 0.3 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EOO04320.1 - 0.051 13.1 0.1 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EOO04320.1 - 0.055 12.9 0.4 0.077 12.4 0.1 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S51 PF03575.12 EOO04320.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Cofilin_ADF PF00241.15 EOO04321.1 - 9.9e-36 122.4 0.3 1.2e-35 122.2 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lamp PF01299.12 EOO04321.1 - 0.066 12.3 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Tenui_NCP PF04876.7 EOO04321.1 - 0.074 12.5 0.3 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein AAA PF00004.24 EOO04323.1 - 6.7e-36 123.4 0.0 4.1e-34 117.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EOO04323.1 - 6e-06 26.4 0.1 0.0021 18.1 0.0 3.3 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EOO04323.1 - 1.7e-05 24.1 0.1 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EOO04323.1 - 3.3e-05 23.8 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EOO04323.1 - 0.0001 22.3 0.2 0.0019 18.1 0.1 3.1 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EOO04323.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EOO04323.1 - 0.0002 20.5 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EOO04323.1 - 0.00032 21.5 0.3 0.0013 19.5 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EOO04323.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EOO04323.1 - 0.0017 18.0 0.1 0.005 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EOO04323.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EOO04323.1 - 0.0045 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 EOO04323.1 - 0.0092 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EOO04323.1 - 0.012 15.2 0.1 0.15 11.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EOO04323.1 - 0.014 14.9 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EOO04323.1 - 0.015 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EOO04323.1 - 0.02 14.8 0.0 0.073 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EOO04323.1 - 0.027 14.2 0.0 0.093 12.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EOO04323.1 - 0.028 14.7 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EOO04323.1 - 0.029 13.7 0.1 0.09 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EOO04323.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EOO04323.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EOO04323.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF849 PF05853.7 EOO04323.1 - 0.096 11.5 0.2 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) KTI12 PF08433.5 EOO04323.1 - 0.1 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GYF PF02213.11 EOO04324.1 - 4.2e-10 39.0 0.2 8e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 GYF domain RNA_pol_Rpb1_5 PF04998.12 EOO04325.1 - 1.7e-87 293.2 0.0 3.6e-87 292.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EOO04325.1 - 1.1e-64 217.3 0.3 2.7e-64 216.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EOO04325.1 - 8.9e-33 113.2 0.0 3.3e-32 111.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EOO04325.1 - 1.3e-16 60.2 0.6 5.5e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EOO04325.1 - 5.6e-07 29.1 1.0 1.3e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Alpha-E PF04168.7 EOO04325.1 - 0.00053 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Nop14 PF04147.7 EOO04325.1 - 0.32 8.8 11.9 0.55 8.0 8.2 1.3 1 0 0 1 1 1 0 Nop14-like family BOP1NT PF08145.7 EOO04326.1 - 3.3e-107 358.0 9.3 5.4e-107 357.3 6.4 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EOO04326.1 - 7.2e-24 82.7 4.7 1.5e-12 46.8 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat BetaGal_dom3 PF13363.1 EOO04326.1 - 0.061 12.7 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 eIF2A PF08662.6 EOO04326.1 - 0.22 11.2 0.0 21 4.7 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1168 PF06658.7 EOO04327.1 - 0.033 13.7 3.6 0.04 13.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PGA2 PF07543.7 EOO04327.1 - 0.083 12.6 2.7 0.088 12.5 1.9 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Rad21_Rec8_N PF04825.8 EOO04328.1 - 4.2e-39 132.9 0.0 7.1e-39 132.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EOO04328.1 - 1.1e-08 34.1 0.4 5.6e-08 31.8 0.1 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EOO04328.1 - 0.001 18.7 0.1 0.034 13.7 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein DnaJ PF00226.26 EOO04329.1 - 2.2e-12 46.5 0.6 4.6e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain E2_bind PF08825.5 EOO04330.1 - 1.3e-30 104.9 0.0 2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EOO04330.1 - 1.9e-26 91.3 0.2 3.1e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EOO04330.1 - 6.2e-14 51.1 1.9 6.2e-14 51.1 1.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EOO04330.1 - 0.00054 20.0 0.1 0.0019 18.2 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 EOO04330.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Ecm33 PF12454.3 EOO04330.1 - 0.044 13.6 2.2 0.16 11.8 1.8 1.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein THOC7 PF05615.8 EOO04331.1 - 8.5e-34 116.7 2.2 8.5e-34 116.7 1.5 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 ATG16 PF08614.6 EOO04331.1 - 0.13 12.0 12.6 0.057 13.2 1.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RTBV_P46 PF06216.6 EOO04331.1 - 1 8.1 5.4 0.69 8.6 0.9 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein TBCA PF02970.11 EOO04332.1 - 5.9e-19 67.9 9.7 9.2e-19 67.3 6.6 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A CENP-Q PF13094.1 EOO04332.1 - 0.0087 16.1 11.2 0.021 14.8 7.7 1.7 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4164 PF13747.1 EOO04332.1 - 0.021 14.9 3.8 0.2 11.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Flagellin_C PF00700.16 EOO04332.1 - 0.046 13.8 1.2 0.3 11.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Phage_lysis PF03245.8 EOO04332.1 - 0.051 13.5 5.8 0.024 14.6 1.6 2.1 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein IncA PF04156.9 EOO04332.1 - 0.073 12.6 9.9 0.088 12.3 6.8 1.1 1 0 0 1 1 1 0 IncA protein KH_5 PF13184.1 EOO04332.1 - 0.092 12.5 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 1 0 NusA-like KH domain HrpB7 PF09486.5 EOO04332.1 - 0.11 12.4 6.6 0.17 11.8 4.6 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ANF_receptor PF01094.23 EOO04332.1 - 0.13 10.9 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region DUF4407 PF14362.1 EOO04332.1 - 0.14 11.0 9.7 0.17 10.8 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.13 EOO04332.1 - 0.16 11.7 1.2 0.3 10.8 0.4 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Remorin_C PF03763.8 EOO04332.1 - 0.17 11.4 6.2 0.28 10.7 4.3 1.5 1 1 0 1 1 1 0 Remorin, C-terminal region Spectrin PF00435.16 EOO04332.1 - 0.19 12.0 6.7 0.081 13.2 2.5 1.8 1 1 1 2 2 2 0 Spectrin repeat DUF4559 PF15112.1 EOO04332.1 - 0.21 10.7 4.2 0.25 10.4 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FadA PF09403.5 EOO04332.1 - 0.28 11.1 5.7 0.36 10.8 4.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Metal_resist PF13801.1 EOO04332.1 - 0.29 11.1 7.5 0.24 11.4 3.3 1.8 2 0 0 2 2 2 0 Heavy-metal resistance ADIP PF11559.3 EOO04332.1 - 0.31 10.9 9.6 0.63 9.9 2.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 EOO04332.1 - 0.58 9.5 5.0 1.5 8.1 0.2 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Pox_A_type_inc PF04508.7 EOO04332.1 - 0.78 9.6 3.7 11 6.0 0.3 2.9 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat OmpH PF03938.9 EOO04332.1 - 0.92 9.4 14.5 3.2 7.6 10.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EOO04332.1 - 1.6 8.9 6.5 21 5.3 4.5 2.0 1 1 0 1 1 1 0 Syntaxin TMF_DNA_bd PF12329.3 EOO04332.1 - 2.2 8.1 12.3 0.24 11.2 1.6 2.5 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EOO04332.1 - 3.4 6.0 9.0 2.8 6.2 1.7 1.6 1 1 1 2 2 2 0 AAA domain Sugarporin_N PF11471.3 EOO04332.1 - 5.3 6.7 7.9 4.2 7.0 0.2 2.8 3 1 0 3 3 2 0 Maltoporin periplasmic N-terminal extension Mnd1 PF03962.10 EOO04332.1 - 8 6.0 9.0 23 4.5 6.3 1.7 1 1 0 1 1 1 0 Mnd1 family DUF4398 PF14346.1 EOO04332.1 - 8.7 6.4 11.8 1.5 8.9 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF925 PF06042.6 EOO04333.1 - 0.032 13.8 0.3 0.034 13.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) HTH_42 PF06224.7 EOO04333.1 - 0.046 13.0 1.0 0.052 12.8 0.7 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DNA_pol_B_3 PF08408.5 EOO04333.1 - 0.07 13.0 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase family B viral insert RE_AlwI PF09491.5 EOO04333.1 - 0.098 11.1 2.7 0.12 10.8 1.9 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease FliG_C PF01706.11 EOO04333.1 - 0.22 11.5 4.9 0.24 11.3 2.1 1.9 1 1 1 2 2 2 0 FliG C-terminal domain Vfa1 PF08432.5 EOO04333.1 - 0.33 10.9 4.5 0.44 10.5 3.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 EOO04333.1 - 0.46 9.3 6.4 0.48 9.2 4.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2884 PF11101.3 EOO04333.1 - 0.49 9.7 6.1 0.29 10.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Phage_GPO PF05929.6 EOO04333.1 - 3.6 6.7 7.8 6.3 5.9 5.4 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Leo1 PF04004.8 EOO04334.1 - 1.1e-34 119.6 0.3 1.1e-34 119.6 0.2 2.1 2 0 0 2 2 2 1 Leo1-like protein TFIIF_beta PF02270.10 EOO04334.1 - 0.042 13.6 1.5 0.088 12.5 1.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit NAD_binding_7 PF13241.1 EOO04334.1 - 0.11 12.8 0.1 0.32 11.2 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF3237 PF11578.3 EOO04335.1 - 3.4e-25 88.1 0.0 3.8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Oxidored_FMN PF00724.15 EOO04336.1 - 4.9e-59 200.0 0.0 6.4e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ThiF PF00899.16 EOO04337.1 - 4.1e-38 130.2 0.1 5.4e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EOO04337.1 - 3.9e-05 23.7 0.3 0.00012 22.1 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EOO04337.1 - 0.014 15.6 0.1 0.023 14.9 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EOO04337.1 - 0.03 14.3 0.1 0.052 13.5 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EOO04337.1 - 0.031 14.6 0.0 0.099 13.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EOO04337.1 - 0.052 12.4 0.1 0.084 11.7 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EOO04337.1 - 0.066 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EOO04337.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Band_7 PF01145.20 EOO04338.1 - 1.2e-23 83.9 2.5 1.8e-23 83.3 1.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Zn_clus PF00172.13 EOO04339.1 - 1.9e-05 24.4 9.8 3.1e-05 23.7 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1003 PF06210.6 EOO04339.1 - 0.22 11.4 0.3 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) RNA_pol_A_bac PF01000.21 EOO04340.1 - 2.3e-28 98.6 0.0 5e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EOO04340.1 - 5.9e-16 57.3 0.0 8.7e-16 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AlaDh_PNT_N PF05222.10 EOO04341.1 - 1.1e-27 96.6 0.0 2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EOO04341.1 - 9.8e-13 48.0 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_phi PF04931.8 EOO04342.1 - 9.5e-57 192.3 45.6 3.7e-55 187.0 31.6 2.6 1 1 0 1 1 1 1 DNA polymerase phi EB1 PF03271.12 EOO04342.1 - 0.026 14.5 0.4 0.32 11.0 0.0 2.7 2 1 1 3 3 3 0 EB1-like C-terminal motif Uteroglobin PF01099.12 EOO04342.1 - 0.026 14.3 5.1 0.056 13.2 0.0 3.4 3 0 0 3 3 3 0 Uteroglobin family Vps35 PF03635.12 EOO04342.1 - 0.14 10.2 7.2 0.019 13.1 0.3 2.4 3 0 0 3 3 3 0 Vacuolar protein sorting-associated protein 35 IncA PF04156.9 EOO04343.1 - 0.0028 17.2 14.5 0.0041 16.7 10.0 1.2 1 0 0 1 1 1 1 IncA protein Matrilin_ccoil PF10393.4 EOO04343.1 - 0.022 14.0 0.1 0.022 14.0 0.0 3.3 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1342 PF07072.6 EOO04343.1 - 0.062 12.9 3.7 0.11 12.1 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1342) PRCC PF10253.4 EOO04343.1 - 0.13 12.9 6.2 0.18 12.4 4.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4613 PF15390.1 EOO04343.1 - 0.24 9.5 8.0 0.35 9.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Hanta_nucleocap PF00846.13 EOO04343.1 - 0.33 9.5 5.3 0.42 9.2 3.7 1.3 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Reo_sigmaC PF04582.7 EOO04343.1 - 0.69 9.0 8.1 1.5 7.9 5.6 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein KxDL PF10241.4 EOO04343.1 - 1.9 8.4 8.7 0.6 10.0 2.4 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein Cauli_AT PF03233.8 EOO04343.1 - 2.1 8.0 14.4 1 9.0 2.4 2.3 1 1 1 2 2 2 0 Aphid transmission protein DUF262 PF03235.9 EOO04343.1 - 2.2 8.1 5.4 2.9 7.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Atg14 PF10186.4 EOO04343.1 - 2.8 6.8 14.1 4.1 6.2 9.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS-augmin3 PF14932.1 EOO04343.1 - 5.1 6.2 16.0 4.6 6.3 9.3 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 EOO04343.1 - 5.4 4.7 14.0 8.6 4.0 9.5 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3153 PF11353.3 EOO04343.1 - 5.7 6.3 7.1 3 7.2 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) CCDC84 PF14968.1 EOO04343.1 - 5.8 6.3 8.6 9.1 5.6 6.0 1.4 1 1 0 1 1 1 0 Coiled coil protein 84 DUF4220 PF13968.1 EOO04343.1 - 7.2 5.6 9.7 0.74 8.8 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) Erp_C PF06780.6 EOO04343.1 - 7.9 6.3 14.5 2.9 7.7 7.5 2.0 1 1 1 2 2 2 0 Erp protein C-terminus RhoGAP PF00620.22 EOO04344.1 - 1e-43 148.5 0.3 1.5e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EOO04344.1 - 9.9e-11 41.7 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EOO04344.1 - 1.2e-07 31.9 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EOO04344.1 - 0.0051 16.8 0.1 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_7 PF15408.1 EOO04344.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Mob1_phocein PF03637.12 EOO04345.1 - 4.1e-36 124.2 2.5 1.9e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family IU_nuc_hydro PF01156.14 EOO04348.1 - 7.9e-70 235.5 0.1 8.8e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Elongin_A PF06881.6 EOO04349.1 - 1.1e-19 70.8 0.7 2.4e-19 69.7 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Proteasome PF00227.21 EOO04350.1 - 5.9e-47 159.4 0.3 2.1e-30 105.4 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EOO04350.1 - 1.4e-11 43.5 0.9 1.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PITH PF06201.8 EOO04351.1 - 9.1e-44 148.8 0.0 1.4e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EOO04351.1 - 5.7e-27 93.4 0.3 1e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EOO04351.1 - 2.9e-07 30.5 0.1 0.00045 20.2 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EOO04351.1 - 2.1e-06 27.8 0.8 1.2e-05 25.4 0.5 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EOO04351.1 - 0.0067 16.1 0.2 0.073 12.7 0.1 2.1 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.6 EOO04351.1 - 0.02 14.8 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 EOO04351.1 - 0.026 14.0 0.3 0.11 12.0 0.2 1.9 1 1 1 2 2 2 0 Redoxin Thioredoxin_7 PF13899.1 EOO04351.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 EOO04351.1 - 0.037 13.5 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 EOO04351.1 - 0.15 11.9 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin domain PRA1 PF03208.14 EOO04353.1 - 4.7e-41 139.6 0.4 5.6e-41 139.4 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein Ni_hydr_CYTB PF01292.15 EOO04353.1 - 0.027 13.8 0.2 0.042 13.2 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4260 PF14079.1 EOO04353.1 - 0.13 12.1 3.4 0.19 11.5 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4260) Fungal_trans_2 PF11951.3 EOO04354.1 - 0.01 14.4 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CorA PF01544.13 EOO04356.1 - 1.2e-37 129.5 1.5 1.6e-36 125.8 1.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Mannosyl_trans3 PF11051.3 EOO04357.1 - 1.3e-68 231.3 0.6 6.9e-68 228.9 0.4 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative ADH_zinc_N PF00107.21 EOO04358.1 - 3.6e-21 75.0 1.0 5.4e-21 74.4 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EOO04358.1 - 1.3e-16 61.6 0.8 4.6e-16 59.8 0.2 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EOO04358.1 - 5.1e-05 22.9 0.2 0.00059 19.5 0.0 2.8 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain LEA_5 PF00477.12 EOO04358.1 - 0.015 15.5 0.4 0.036 14.3 0.3 1.6 1 0 0 1 1 1 0 Small hydrophilic plant seed protein AlaDh_PNT_C PF01262.16 EOO04358.1 - 0.016 14.7 0.3 0.029 13.9 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1509 PF07420.6 EOO04359.1 - 1.4 8.0 10.8 1.9 7.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MFS_1 PF07690.11 EOO04360.1 - 2.6e-34 118.5 57.9 1.8e-31 109.1 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EOO04360.1 - 7.1e-06 24.7 5.9 7.1e-06 24.7 4.1 3.7 2 2 1 4 4 4 2 Vacuole effluxer Atg22 like CSTF2_hinge PF14327.1 EOO04361.1 - 2.7e-30 104.2 2.8 2.7e-30 104.2 2.0 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EOO04361.1 - 7.6e-22 76.7 0.0 1.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04361.1 - 2.1e-16 59.6 0.0 4.4e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04361.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EOO04361.1 - 0.0022 17.2 5.5 0.0022 17.2 3.8 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal PAT1 PF09770.4 EOO04361.1 - 1.6 6.8 9.6 1.9 6.6 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 EOO04362.1 - 1.3e-61 208.5 26.9 1.5e-61 208.3 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04362.1 - 1.4e-19 70.0 38.5 8.1e-14 51.1 11.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COG4 PF08318.7 EOO04363.1 - 1.6e-95 319.6 0.0 2.2e-95 319.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.15 EOO04363.1 - 1.4e-73 246.7 0.1 2.1e-73 246.1 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EOO04363.1 - 5.3e-30 105.4 0.0 4.8e-29 102.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EOO04363.1 - 1.4e-28 99.6 0.1 2.9e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EOO04363.1 - 7.5e-19 66.9 0.0 2e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EOO04363.1 - 1.3e-13 50.6 0.0 3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EOO04363.1 - 1.5e-13 51.3 0.1 2.4e-12 47.4 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EOO04363.1 - 6e-05 22.7 0.9 6e-05 22.7 0.6 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dynamitin PF04912.9 EOO04364.1 - 5.5e-36 124.1 7.5 2.7e-18 65.9 5.8 2.6 2 1 0 2 2 2 2 Dynamitin Laminin_II PF06009.7 EOO04364.1 - 0.0016 18.1 13.2 0.018 14.7 0.1 4.7 4 1 1 5 5 5 1 Laminin Domain II FH2 PF02181.18 EOO04364.1 - 0.0061 15.5 4.9 0.23 10.3 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Spore_III_AB PF09548.5 EOO04364.1 - 0.02 14.6 4.6 0.034 13.9 0.2 2.6 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF972 PF06156.8 EOO04364.1 - 0.022 15.1 3.9 1.9 8.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EOO04364.1 - 0.097 12.4 0.3 2.1 8.1 0.1 2.6 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EOO04364.1 - 0.12 12.5 8.4 2.4 8.3 0.1 4.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 EOO04364.1 - 0.17 11.7 1.9 8.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ATP-synt_E PF05680.7 EOO04364.1 - 0.24 11.3 5.8 0.2 11.6 0.8 2.5 2 0 0 2 2 2 0 ATP synthase E chain RmuC PF02646.11 EOO04364.1 - 0.45 9.3 5.1 0.099 11.4 0.2 2.2 3 0 0 3 3 3 0 RmuC family FlgN PF05130.7 EOO04364.1 - 0.54 10.5 20.2 0.043 14.0 3.4 3.3 2 1 1 3 3 3 0 FlgN protein IncA PF04156.9 EOO04364.1 - 0.57 9.7 10.6 2.6 7.5 0.4 3.0 3 0 0 3 3 3 0 IncA protein DUF904 PF06005.7 EOO04364.1 - 0.66 10.3 8.7 3 8.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Sipho_Gp157 PF05565.6 EOO04364.1 - 0.75 9.3 0.0 0.75 9.3 0.0 3.2 3 1 0 3 3 3 0 Siphovirus Gp157 DivIVA PF05103.8 EOO04364.1 - 0.87 9.6 9.2 9.7 6.2 0.4 3.1 2 1 1 3 3 3 0 DivIVA protein COG2 PF06148.6 EOO04364.1 - 0.94 9.3 5.8 2.6 7.9 0.2 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 EOO04364.1 - 1.1 8.8 10.1 0.58 9.7 0.7 3.0 3 0 0 3 3 3 0 Mnd1 family DegS PF05384.6 EOO04364.1 - 1.2 8.3 6.4 0.33 10.1 0.3 2.8 4 0 0 4 4 4 0 Sensor protein DegS Tropomyosin_1 PF12718.2 EOO04364.1 - 1.3 8.9 16.9 1.6 8.5 0.9 3.4 3 0 0 3 3 3 0 Tropomyosin like Cwf_Cwc_15 PF04889.7 EOO04364.1 - 1.4 8.5 12.9 0.6 9.7 6.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Phage_GP20 PF06810.6 EOO04364.1 - 1.6 8.1 10.0 0.27 10.6 0.9 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 Viral_P18 PF04521.8 EOO04364.1 - 2.1 7.7 6.6 3.2 7.2 0.1 3.2 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 EOO04364.1 - 8.6 5.9 15.8 0.89 9.0 0.3 3.9 3 1 0 3 3 3 0 Septum formation initiator SURF4 PF02077.10 EOO04365.1 - 7.9e-100 333.6 7.7 9e-100 333.4 5.4 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 EOO04365.1 - 3.9 7.6 16.2 0.96 9.6 0.7 2.8 2 1 0 2 2 2 0 Type IV leader peptidase family FA_desaturase PF00487.19 EOO04365.1 - 6.1 6.2 12.5 4.5 6.6 5.9 2.4 1 1 1 2 2 2 0 Fatty acid desaturase DUF1129 PF06570.6 EOO04365.1 - 8 5.7 8.5 0.7 9.1 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Lipase_GDSL PF00657.17 EOO04366.1 - 1.8e-16 60.7 1.3 4.3e-16 59.4 0.9 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EOO04366.1 - 2.2e-16 60.5 3.7 3.4e-16 59.8 2.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family G-patch PF01585.18 EOO04368.1 - 0.00043 19.9 0.0 0.0017 18.0 0.0 2.0 1 1 0 1 1 1 1 G-patch domain BTB PF00651.26 EOO04368.1 - 0.0009 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ycf1 PF05758.7 EOO04368.1 - 0.47 8.1 12.3 0.77 7.4 8.5 1.2 1 0 0 1 1 1 0 Ycf1 Sec62 PF03839.11 EOO04368.1 - 2.4 7.5 21.4 3.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Translocation protein Sec62 DnaJ PF00226.26 EOO04370.1 - 2.8e-19 68.6 0.7 4.4e-19 67.9 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EOO04370.1 - 0.021 14.8 2.5 0.03 14.3 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Sugar_tr PF00083.19 EOO04371.1 - 4.7e-78 262.7 26.2 5.6e-78 262.5 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EOO04371.1 - 2.8e-16 59.1 32.3 2.8e-16 59.1 22.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2574 PF10836.3 EOO04371.1 - 0.078 12.6 0.1 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) NAD_binding_10 PF13460.1 EOO04372.1 - 5.4e-20 72.1 0.8 7.2e-20 71.7 0.6 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO04372.1 - 7.3e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EOO04372.1 - 0.036 12.9 0.0 0.12 11.1 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EOO04372.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glyco_hydro_3_C PF01915.17 EOO04373.1 - 1.3e-54 185.1 0.0 2.5e-54 184.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EOO04373.1 - 3.5e-19 68.4 1.6 2e-18 66.0 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 EOO04373.1 - 0.00065 19.6 1.1 0.0016 18.4 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF11 PA14 PF07691.7 EOO04373.1 - 0.0068 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 PA14 domain NPCBM_assoc PF10633.4 EOO04373.1 - 0.58 10.2 4.9 0.82 9.7 0.3 2.9 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FAD_binding_4 PF01565.18 EOO04374.1 - 7.9e-18 64.2 1.2 1.7e-17 63.1 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EOO04374.1 - 5e-07 29.5 0.3 9.4e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like BCNT PF07572.7 EOO04375.1 - 4.5e-26 90.5 2.3 1e-25 89.4 1.6 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development TIM PF00121.13 EOO04376.1 - 5.9e-87 290.7 0.1 7e-87 290.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EOO04376.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 CutC family AA_kinase PF00696.23 EOO04377.1 - 6.2e-25 88.1 0.9 1.1e-24 87.3 0.6 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EOO04377.1 - 1.3e-17 63.2 0.1 2.4e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 PUA domain Lon_C PF05362.8 EOO04377.1 - 0.02 14.2 0.1 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain AMP-binding PF00501.23 EOO04378.1 - 4e-10 38.6 0.0 5.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EOO04378.1 - 6e-06 27.1 0.0 9.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Dioxygenase_C PF00775.16 EOO04379.1 - 5e-50 169.2 0.0 6.3e-50 168.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EOO04379.1 - 4.4e-11 42.6 0.0 8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EOO04379.1 - 0.00064 19.7 0.0 0.0093 15.9 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cytochrom_B561 PF03188.11 EOO04380.1 - 1.7e-06 27.8 5.7 1.7e-06 27.8 4.0 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 EOO04380.1 - 0.036 13.7 0.5 0.036 13.7 0.3 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF2427 PF10348.4 EOO04380.1 - 0.081 12.5 9.1 0.019 14.5 3.7 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF998 PF06197.8 EOO04380.1 - 0.11 11.7 17.7 0.033 13.5 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) MARVEL PF01284.18 EOO04380.1 - 0.22 11.3 7.0 3.4 7.4 1.1 2.2 2 0 0 2 2 2 0 Membrane-associating domain DUF4079 PF13301.1 EOO04380.1 - 0.56 10.1 10.4 2.8 7.9 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MRAP PF15183.1 EOO04380.1 - 7.6 6.2 6.6 2.2 7.9 0.1 2.7 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family MFS_1 PF07690.11 EOO04381.1 - 3.5e-11 42.4 30.0 1.4e-06 27.2 2.7 4.0 2 1 2 4 4 4 2 Major Facilitator Superfamily MFS_2 PF13347.1 EOO04381.1 - 8.4e-09 34.3 6.1 8.4e-09 34.3 4.2 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein DUF3169 PF11368.3 EOO04381.1 - 2.5 7.2 6.4 7.4 5.6 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Pkinase PF00069.20 EOO04382.1 - 1.9e-69 233.7 0.0 2.4e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04382.1 - 2.9e-43 147.8 0.0 3.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04382.1 - 1.2e-07 30.9 0.0 3.9e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EOO04382.1 - 0.00097 18.2 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EOO04382.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EOO04382.1 - 0.014 14.7 0.0 0.056 12.7 0.0 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.18 EOO04382.1 - 0.025 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nnf1 PF03980.9 EOO04383.1 - 3.8e-30 104.0 0.5 8.3e-30 102.9 0.3 1.6 1 0 0 1 1 1 1 Nnf1 Laminin_I PF06008.9 EOO04383.1 - 0.023 14.0 0.8 0.023 14.0 0.6 1.7 2 0 0 2 2 2 0 Laminin Domain I LOH1CR12 PF10158.4 EOO04383.1 - 0.024 14.4 0.3 0.062 13.0 0.1 1.8 2 0 0 2 2 2 0 Tumour suppressor protein DUF972 PF06156.8 EOO04383.1 - 0.06 13.6 1.0 3.7 7.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) YqjK PF13997.1 EOO04383.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 YqjK-like protein TMCO5 PF14992.1 EOO04383.1 - 0.12 11.5 1.4 0.2 10.7 1.0 1.4 1 0 0 1 1 1 0 TMCO5 family FliT PF05400.8 EOO04383.1 - 0.22 11.9 4.7 0.52 10.7 2.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Baculo_PEP_C PF04513.7 EOO04383.1 - 0.33 10.7 3.6 0.54 10.0 0.9 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.9 EOO04383.1 - 0.38 10.6 4.6 0.28 11.1 0.2 2.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) adh_short PF00106.20 EOO04384.1 - 8.9e-16 58.2 0.0 2.1e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 EOO04384.1 - 0.015 14.3 0.1 0.06 12.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EOO04384.1 - 0.016 15.2 0.1 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EOO04384.1 - 0.026 14.3 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EOO04384.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 KR domain Acyltransferase PF01553.16 EOO04385.1 - 5.9e-15 54.8 0.0 1.5e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase PH_9 PF15410.1 EOO04386.1 - 0.00036 20.6 0.0 0.00048 20.2 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PrpF PF04303.8 EOO04387.1 - 1.4e-79 267.5 1.5 1.5e-79 267.4 1.0 1.0 1 0 0 1 1 1 1 PrpF protein PilZ PF07238.9 EOO04387.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 PilZ domain SRP9-21 PF05486.7 EOO04388.1 - 3.2e-27 94.0 0.0 4e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) PX PF00787.19 EOO04389.1 - 1.6e-19 69.7 0.0 7.3e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EOO04389.1 - 1.6e-16 60.3 9.4 1.5e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like RNA_polI_A14 PF08203.6 EOO04389.1 - 1.1 9.5 5.1 0.64 10.3 0.4 2.7 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 adh_short PF00106.20 EOO04390.1 - 7.8e-19 68.2 1.3 1.6e-18 67.2 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO04390.1 - 7.1e-14 52.1 0.0 8.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO04390.1 - 0.00097 18.8 1.1 0.004 16.8 0.8 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 EOO04390.1 - 0.0025 17.8 1.7 0.0034 17.4 0.9 1.5 1 1 0 1 1 1 1 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EOO04390.1 - 0.016 14.9 0.1 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EOO04390.1 - 0.048 13.1 0.1 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SNF5 PF04855.7 EOO04391.1 - 8.5e-77 257.9 0.3 1.5e-76 257.1 0.2 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 CoA_transf_3 PF02515.12 EOO04392.1 - 4.7e-29 101.0 0.0 5.8e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Polysacc_lyase PF14099.1 EOO04393.1 - 0.014 15.0 7.5 0.022 14.4 5.2 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Rdx PF10262.4 EOO04394.1 - 9.7e-17 60.7 0.0 1.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family Ribosomal_60s PF00428.14 EOO04394.1 - 3.8 7.9 12.9 0.54 10.7 1.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2457 PF10446.4 EOO04396.1 - 7.6e-149 496.3 25.4 7.6e-149 496.3 17.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) DUF3499 PF12005.3 EOO04396.1 - 1.4 9.0 5.6 0.67 10.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF1032 PF06278.6 EOO04396.1 - 8.4 4.7 17.1 21 3.4 11.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1032) Peptidase_M24 PF00557.19 EOO04397.1 - 4.1e-10 39.5 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SCA7 PF08313.7 EOO04398.1 - 7.8e-35 118.3 0.3 7.8e-35 118.3 0.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2457 PF10446.4 EOO04398.1 - 0.0032 16.2 15.7 0.0051 15.5 10.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Omega-toxin PF06357.6 EOO04398.1 - 0.06 12.9 0.1 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Omega-atracotoxin TRAP_alpha PF03896.11 EOO04398.1 - 6 5.7 6.7 11 4.9 4.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit U79_P34 PF03064.11 EOO04398.1 - 7.8 5.9 21.0 13 5.2 14.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Metallophos PF00149.23 EOO04399.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EOO04401.1 - 1.7e-29 101.2 15.9 9.9e-08 31.5 0.1 9.0 6 3 5 11 11 11 7 TPR repeat TPR_1 PF00515.23 EOO04401.1 - 2.5e-27 93.3 15.9 7.3e-05 22.1 0.0 11.9 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.12 EOO04401.1 - 5.5e-24 82.0 24.5 0.0053 16.5 0.0 12.5 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 EOO04401.1 - 4.9e-23 81.2 15.1 6.2e-06 26.4 0.1 10.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EOO04401.1 - 2.7e-21 73.6 14.4 0.00078 19.0 0.0 11.7 12 1 0 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.1 EOO04401.1 - 5.5e-19 67.8 26.1 3.2e-05 23.7 0.1 10.5 7 3 6 13 13 13 9 Tetratricopeptide repeat TPR_7 PF13176.1 EOO04401.1 - 4.9e-18 63.4 18.4 2.2e-05 23.9 0.0 10.2 11 1 1 12 12 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EOO04401.1 - 3.2e-15 55.2 30.2 0.00048 20.5 0.0 13.3 13 4 2 15 15 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 EOO04401.1 - 8.8e-13 48.5 35.9 0.0027 18.3 0.0 10.6 10 3 2 13 13 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 EOO04401.1 - 1.9e-11 43.6 13.3 0.0096 16.3 0.0 10.2 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EOO04401.1 - 1.1e-09 37.7 7.8 0.052 13.7 0.2 10.3 11 0 0 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EOO04401.1 - 5.9e-09 35.9 12.2 0.043 13.9 0.2 7.6 6 1 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EOO04401.1 - 1.2e-05 25.0 3.9 0.51 10.3 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EOO04401.1 - 0.013 15.0 0.2 0.013 15.0 0.2 4.3 6 0 0 6 6 5 0 Foie gras liver health family 1 Pkinase PF00069.20 EOO04402.1 - 7.2e-72 241.6 0.1 1.2e-71 240.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04402.1 - 1e-53 182.0 0.2 1.8e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EOO04402.1 - 3.7e-23 81.6 0.8 8.5e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EOO04402.1 - 8.1e-09 34.8 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EOO04402.1 - 1.5e-08 34.9 0.5 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 EOO04402.1 - 0.0019 18.0 1.9 0.0039 16.9 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EOO04402.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAT1 PF09770.4 EOO04402.1 - 8.8 4.4 23.2 16 3.5 16.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulase PF00150.13 EOO04403.1 - 8.8e-19 67.7 0.5 1.7e-18 66.8 0.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) B12-binding PF02310.14 EOO04403.1 - 0.11 12.3 0.0 3.8 7.4 0.0 2.4 2 1 0 2 2 2 0 B12 binding domain Peptidase_M76 PF09768.4 EOO04404.1 - 7.8e-68 227.3 1.9 9.6e-68 227.0 1.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EOO04404.1 - 2.3 7.8 8.4 0.28 10.8 1.8 2.2 1 1 0 2 2 2 0 SprT-like family AAA PF00004.24 EOO04407.1 - 1.8e-45 154.3 0.0 9.1e-42 142.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EOO04407.1 - 1.3e-05 25.2 1.6 3.9e-05 23.7 0.0 2.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 EOO04407.1 - 1.6e-05 24.9 0.0 5.1e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EOO04407.1 - 6.6e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EOO04407.1 - 0.00027 21.0 0.1 0.0072 16.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EOO04407.1 - 0.00042 20.0 0.0 0.0018 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EOO04407.1 - 0.002 16.8 0.0 0.0041 15.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Bromodomain PF00439.20 EOO04407.1 - 0.0021 17.9 0.0 0.0096 15.8 0.0 2.1 2 0 0 2 2 1 1 Bromodomain AAA_33 PF13671.1 EOO04407.1 - 0.0034 17.2 0.2 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EOO04407.1 - 0.019 15.1 0.0 0.072 13.2 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.1 EOO04407.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EOO04407.1 - 0.032 14.5 0.0 0.54 10.5 0.0 3.0 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EOO04407.1 - 0.033 15.0 0.0 0.033 15.0 0.0 3.6 4 1 0 4 4 3 0 AAA domain RuvB_N PF05496.7 EOO04407.1 - 0.035 13.1 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EOO04407.1 - 0.035 14.1 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EOO04407.1 - 0.038 14.2 0.0 0.038 14.2 0.0 3.8 5 0 0 5 5 3 0 AAA domain Mg_chelatase PF01078.16 EOO04407.1 - 0.05 12.7 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EOO04407.1 - 0.06 13.1 0.1 0.06 13.1 0.1 2.2 2 0 0 2 2 1 0 Part of AAA domain NACHT PF05729.7 EOO04407.1 - 0.16 11.6 0.1 0.4 10.3 0.1 1.7 1 1 0 1 1 1 0 NACHT domain Pkinase PF00069.20 EOO04408.1 - 1e-77 260.8 0.0 1.2e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04408.1 - 1.2e-37 129.4 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EOO04408.1 - 0.0097 14.8 0.0 0.027 13.4 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EOO04408.1 - 0.036 13.7 0.6 0.14 11.8 0.0 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EOO04408.1 - 0.047 12.7 0.1 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WSC PF01822.14 EOO04409.1 - 2.1e-41 139.7 26.7 3.2e-21 75.0 7.5 2.2 2 0 0 2 2 2 2 WSC domain TruB-C_2 PF09157.6 EOO04410.1 - 0.055 13.3 0.0 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal PBP1_TM PF14812.1 EOO04411.1 - 6.8 7.0 9.9 1.8 8.8 0.6 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.22 EOO04413.1 - 6e-44 147.6 2.4 7.6e-22 76.8 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein HEAT_2 PF13646.1 EOO04414.1 - 8.4e-07 29.1 2.2 0.85 9.9 0.0 5.9 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 EOO04414.1 - 7.8e-06 25.5 3.8 4.7 7.5 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat DUF3734 PF12536.3 EOO04414.1 - 0.12 12.5 3.6 0.3 11.2 0.1 3.1 2 0 0 2 2 2 0 Patatin phospholipase HEAT_EZ PF13513.1 EOO04414.1 - 1.9 9.0 8.5 2.7 8.6 0.0 5.2 7 0 0 7 7 7 0 HEAT-like repeat PUF PF00806.14 EOO04415.1 - 6.3e-28 94.6 0.0 2.6e-05 23.4 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EOO04415.1 - 1.1e-13 50.5 0.0 2.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04415.1 - 7.7e-07 28.8 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04415.1 - 1.6e-06 27.9 0.0 5.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.8 EOO04415.1 - 0.42 9.4 9.6 0.76 8.5 6.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAPEG PF01124.13 EOO04416.1 - 3.9e-13 49.1 1.4 4.9e-13 48.8 1.0 1.1 1 0 0 1 1 1 1 MAPEG family Pkinase PF00069.20 EOO04417.1 - 3e-50 170.8 0.0 5.6e-50 169.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EOO04417.1 - 1e-23 83.7 0.0 1.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EOO04417.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EOO04417.1 - 0.0019 17.5 0.2 0.0065 15.8 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EOO04417.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Choline_kinase PF01633.15 EOO04417.1 - 0.38 10.2 2.0 0.32 10.5 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.17 EOO04418.1 - 1.6e-61 203.8 0.0 1.8e-21 75.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04418.1 - 2.1e-43 146.1 0.0 4.3e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04418.1 - 2.4e-31 107.3 0.0 9.1e-11 41.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EOO04418.1 - 1.3e-06 28.0 0.0 0.0052 16.5 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EOO04418.1 - 0.0029 17.5 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.3 EOO04418.1 - 0.06 13.1 0.0 14 5.5 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.6 EOO04418.1 - 0.15 11.9 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif WD40 PF00400.27 EOO04419.1 - 9.4e-21 72.8 4.1 2.2e-11 43.1 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EOO04419.1 - 0.038 12.7 0.0 4.2 5.9 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like L51_S25_CI-B8 PF05047.11 EOO04420.1 - 8.8e-15 54.1 0.0 1.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Metallophos PF00149.23 EOO04422.1 - 9.7e-10 38.1 4.4 1.6e-09 37.4 3.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EOO04422.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF3391 PF11871.3 EOO04423.1 - 6.2 7.0 7.7 0.39 10.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) RNA_pol_I_A49 PF06870.7 EOO04424.1 - 7.5e-78 261.7 0.3 9.7e-78 261.4 0.2 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor RTA1 PF04479.8 EOO04425.1 - 1.9e-37 128.9 3.2 2.9e-37 128.3 2.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 EOO04425.1 - 0.094 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal RRM_6 PF14259.1 EOO04426.1 - 0.0028 17.5 0.1 0.25 11.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Biotin_lipoyl PF00364.17 EOO04427.1 - 3.8e-19 68.0 2.3 7.5e-19 67.1 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EOO04427.1 - 4e-07 29.5 0.0 1.4e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EOO04427.1 - 5.3e-05 22.7 0.0 0.00029 20.4 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 EOO04427.1 - 0.0085 15.4 0.1 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 EOO04427.1 - 0.01 15.0 1.0 0.2 10.7 0.7 2.1 1 1 0 1 1 1 0 HlyD family secretion protein HlyD_3 PF13437.1 EOO04427.1 - 0.082 13.2 0.4 1.8 8.9 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Trypan_PARP PF05887.6 EOO04427.1 - 0.31 10.8 12.1 0.044 13.6 5.3 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MIF4G PF02854.14 EOO04429.1 - 3.8e-52 176.7 0.0 6.8e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EOO04429.1 - 8.9e-21 73.5 0.6 2.6e-20 72.1 0.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Daxx PF03344.10 EOO04429.1 - 1.6 7.1 42.8 2.9 6.2 29.7 1.4 1 0 0 1 1 1 0 Daxx Family Arf PF00025.16 EOO04430.1 - 3e-66 221.9 0.0 3.4e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EOO04430.1 - 4.3e-10 38.8 0.1 1.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EOO04430.1 - 5.6e-08 33.3 0.0 7.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EOO04430.1 - 2e-07 30.5 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EOO04430.1 - 2.4e-07 30.1 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EOO04430.1 - 2.8e-07 30.4 0.0 3.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EOO04430.1 - 7e-06 25.3 0.0 7.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EOO04430.1 - 0.0002 20.8 0.1 0.0089 15.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 EOO04430.1 - 0.099 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 EOO04430.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EOO04430.1 - 0.15 11.4 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Na_H_Exchanger PF00999.16 EOO04431.1 - 7.3e-68 228.8 32.0 8.9e-68 228.5 22.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3149 PF11346.3 EOO04431.1 - 0.06 12.9 3.3 0.32 10.5 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) PepSY_TM_2 PF13703.1 EOO04431.1 - 0.1 12.7 0.3 0.1 12.7 0.2 3.9 5 1 0 5 5 5 0 PepSY-associated TM helix Ribonuc_red_sm PF00268.16 EOO04432.1 - 2.4e-119 397.5 1.3 2.9e-119 397.2 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain U1snRNP70_N PF12220.3 EOO04433.1 - 1.1e-31 108.9 0.5 1.9e-31 108.2 0.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EOO04433.1 - 1.4e-10 40.6 0.2 2.1e-09 36.8 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04433.1 - 3.1e-07 30.2 0.1 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04433.1 - 0.033 14.0 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HET PF06985.6 EOO04434.1 - 8.1e-15 55.1 0.0 1.6e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIP41 PF04176.8 EOO04435.1 - 9.3e-74 246.6 0.0 1.1e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family RRM_1 PF00076.17 EOO04436.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04436.1 - 0.0041 17.0 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04436.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.22 EOO04437.1 - 0.057 12.6 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain ADH_N PF08240.7 EOO04438.1 - 3.7e-23 81.3 1.6 8e-23 80.2 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EOO04438.1 - 4.1e-10 39.2 0.1 6.8e-09 35.3 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EOO04438.1 - 1.3e-05 24.8 0.1 2.3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EOO04438.1 - 2.1e-05 23.7 0.1 3.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EOO04438.1 - 0.0066 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EOO04438.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dynamin_N PF00350.18 EOO04440.1 - 4.6e-07 29.8 0.1 1.9e-06 27.7 0.0 2.0 1 1 1 2 2 2 1 Dynamin family Syntaxin-6_N PF09177.6 EOO04440.1 - 0.81 10.1 4.8 2.7 8.4 0.2 3.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal ADIP PF11559.3 EOO04440.1 - 1 9.2 7.4 0.071 13.0 0.3 2.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EOO04440.1 - 8.8 5.1 8.2 0.79 8.6 0.4 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 adh_short PF00106.20 EOO04441.1 - 1.5e-18 67.2 0.4 4.3e-18 65.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EOO04441.1 - 6.6e-05 22.8 0.1 8.8e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EOO04441.1 - 0.0032 17.1 0.1 0.005 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EOO04441.1 - 0.041 13.3 0.1 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EOO04441.1 - 0.072 13.0 0.1 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding NTF2 PF02136.15 EOO04442.1 - 3.7e-24 85.3 0.4 5.6e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EOO04442.1 - 2.2e-06 27.2 0.1 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EOO04442.1 - 2.5e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EOO04442.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EOO04442.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF4112 PF13430.1 EOO04443.1 - 2.5e-34 117.3 0.5 3.4e-34 116.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PHD PF00628.24 EOO04444.1 - 6.2e-14 51.4 19.3 1.3e-08 34.3 6.9 2.4 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EOO04444.1 - 0.0068 16.1 12.8 0.084 12.6 1.3 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EOO04444.1 - 0.012 14.8 7.9 0.041 13.1 1.3 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 EOO04444.1 - 0.015 15.4 4.7 0.037 14.1 0.3 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 EOO04444.1 - 0.3 10.8 10.5 1.4 8.6 0.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_2 PF12674.2 EOO04444.1 - 8.1 6.8 6.8 53 4.2 4.7 2.3 1 1 0 1 1 1 0 Putative zinc ribbon domain mRNA_cap_enzyme PF01331.14 EOO04446.1 - 1.9e-53 181.0 0.2 2.5e-53 180.6 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EOO04446.1 - 2.8e-22 78.9 0.0 4.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EOO04446.1 - 6.2e-08 32.2 0.1 2.2e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SH3_1 PF00018.23 EOO04447.1 - 1.4e-05 24.3 0.0 3.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EOO04447.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3336 PF11815.3 EOO04448.1 - 3.2e-54 182.3 8.6 5.2e-54 181.7 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EOO04448.1 - 6.4e-21 75.2 0.0 4.6e-20 72.4 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C2H2 PF00096.21 EOO04449.1 - 6.8e-08 32.4 19.2 1.4e-05 25.1 2.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EOO04449.1 - 2.4e-05 24.3 3.8 2.4e-05 24.3 2.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EOO04449.1 - 0.00049 20.2 0.9 0.00049 20.2 0.6 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EOO04449.1 - 0.00081 19.4 1.0 0.00081 19.4 0.7 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EOO04449.1 - 0.12 12.5 2.5 0.29 11.4 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EOO04449.1 - 0.15 12.0 3.7 0.54 10.2 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EOO04449.1 - 0.63 10.1 4.9 3.7 7.7 3.5 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EOO04449.1 - 1 9.8 7.5 0.12 12.7 2.1 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger G-gamma PF00631.17 EOO04450.1 - 9e-27 92.6 0.0 1.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 EOO04451.1 - 3.7e-09 36.8 0.4 3.5e-08 33.7 0.0 2.7 2 0 0 2 2 2 1 PCI domain Cellulase PF00150.13 EOO04452.1 - 1.1e-14 54.2 5.8 1.4e-14 53.9 4.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rad50_zn_hook PF04423.9 EOO04453.1 - 0.024 14.1 5.0 0.23 10.9 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif OmpH PF03938.9 EOO04453.1 - 0.21 11.4 7.9 0.36 10.7 5.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DZR PF12773.2 EOO04453.1 - 0.54 10.1 6.0 4.7 7.1 2.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF3811 PF11656.3 EOO04453.1 - 3 7.9 12.1 1.8 8.7 0.5 3.7 4 1 0 4 4 4 0 YjbD family (DUF3811) E6 PF00518.12 EOO04453.1 - 4.3 7.7 8.1 3 8.2 0.9 2.8 2 1 1 3 3 3 0 Early Protein (E6) DUF2256 PF10013.4 EOO04453.1 - 5 6.9 6.1 8.7 6.1 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4407 PF14362.1 EOO04453.1 - 6.8 5.5 8.2 10 4.9 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RTA1 PF04479.8 EOO04454.1 - 2.1e-41 141.8 6.3 2.9e-41 141.4 4.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4079 PF13301.1 EOO04454.1 - 1.1 9.2 7.2 3.1 7.7 4.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) FYVE_2 PF02318.11 EOO04455.1 - 0.97 9.3 3.8 1.7 8.5 2.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DNA_pol_B PF00136.16 EOO04456.1 - 8.4e-113 377.6 3.0 8.4e-113 377.6 2.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EOO04456.1 - 3.4e-66 222.1 0.0 6.6e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EOO04456.1 - 1.4e-40 139.1 0.0 2.8e-40 138.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EOO04456.1 - 1e-24 86.1 10.4 5.3e-24 83.8 7.2 2.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Lar_restr_allev PF14354.1 EOO04456.1 - 0.087 13.1 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar EPL1 PF10513.4 EOO04457.1 - 1.5e-20 74.0 0.1 1.5e-20 74.0 0.0 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like TMEM171 PF15471.1 EOO04457.1 - 0.91 8.2 2.6 1.7 7.3 1.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 OPT PF03169.10 EOO04458.1 - 2.1e-38 132.1 5.0 2.6e-38 131.8 3.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DHFR_1 PF00186.14 EOO04460.1 - 1.4e-29 102.7 0.0 3.4e-29 101.5 0.0 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase Ribosomal_L10 PF00466.15 EOO04461.1 - 7.5e-23 80.3 0.0 1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 UPF0113 PF03657.8 EOO04462.1 - 9.6e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EOO04462.1 - 0.044 13.4 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 EOO04462.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis ATP-synt_DE_N PF02823.11 EOO04463.1 - 8.8e-20 70.2 0.1 1.3e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain WW PF00397.21 EOO04464.1 - 5.2e-07 29.4 1.4 1.5e-06 27.9 1.0 1.8 1 0 0 1 1 1 1 WW domain adh_short_C2 PF13561.1 EOO04465.1 - 3.4e-32 112.1 0.1 4e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EOO04465.1 - 1.1e-30 106.7 1.2 1.1e-30 106.7 0.8 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EOO04465.1 - 4.7e-13 49.2 0.3 6.5e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EOO04465.1 - 2.9e-05 24.1 0.1 5e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EOO04465.1 - 0.0045 16.4 0.0 0.029 13.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EOO04465.1 - 0.051 13.2 0.2 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMN_dh PF01070.13 EOO04466.1 - 1.5e-45 155.5 0.0 1.8e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ApbA_C PF08546.6 EOO04467.1 - 1.1e-27 96.5 0.0 1.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EOO04467.1 - 6.9e-21 74.2 0.6 2.4e-19 69.2 0.4 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EOO04467.1 - 0.048 13.4 1.0 0.27 11.0 0.5 2.1 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 EOO04468.1 - 1.7e-12 46.7 7.4 7e-12 44.7 4.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.7 EOO04468.1 - 0.25 10.6 9.8 0.4 9.9 4.5 2.0 1 1 1 2 2 2 0 5TMR of 5TMR-LYT FUSC_2 PF13515.1 EOO04468.1 - 1.6 8.6 13.5 0.88 9.4 7.8 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein-like