# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PT PF04886.7 ETS72872.1 - 1.9e-08 33.4 25.5 1.5e-07 30.6 17.7 2.2 1 1 0 1 1 1 1 PT repeat DUF4106 PF13388.1 ETS72872.1 - 0.14 11.1 15.3 0.028 13.3 8.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Dimer_Tnp_hAT PF05699.9 ETS72873.1 - 6.2e-15 54.5 0.0 1.4e-12 47.0 0.0 3.3 3 0 0 3 3 3 2 hAT family C-terminal dimerisation region DUF3505 PF12013.3 ETS72874.1 - 1.2e-31 109.1 4.5 1.2e-31 109.1 3.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 ETS72874.1 - 0.059 13.6 0.6 0.059 13.6 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DEAD PF00270.24 ETS72875.1 - 4.1e-14 52.4 0.0 6.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS72875.1 - 1.8e-05 24.6 0.0 0.00022 21.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS72875.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Thioredoxin_6 PF13848.1 ETS72876.1 - 2.4e-22 79.6 0.0 3.5e-18 66.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 ETS72876.1 - 1.1e-05 25.0 0.0 0.00069 19.2 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin Nol1_Nop2_Fmu PF01189.12 ETS72877.1 - 2.7e-17 63.0 0.0 6.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family Cut8_N PF14482.1 ETS72877.1 - 0.05 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DUF1996 PF09362.5 ETS72878.1 - 1e-64 218.4 0.1 1e-64 218.4 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Aminotran_3 PF00202.16 ETS72879.1 - 6.2e-70 235.7 0.1 7.8e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SnoaL_4 PF13577.1 ETS72880.1 - 1.2e-13 51.1 0.3 1.4e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain CMD PF02627.15 ETS72881.1 - 0.012 15.4 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF310 PF03750.8 ETS72881.1 - 0.047 13.8 0.2 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF310) ADH_N PF08240.7 ETS72882.1 - 1.7e-25 88.8 3.1 3.1e-25 88.0 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS72882.1 - 1.8e-08 33.9 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1273 PF06908.6 ETS72882.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) 2-Hacid_dh_C PF02826.14 ETS72882.1 - 0.068 12.3 0.4 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Xpo1 PF08389.7 ETS72883.1 - 1e-30 106.6 0.1 1e-30 106.6 0.1 3.6 5 1 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.17 ETS72883.1 - 0.00048 19.9 0.3 5.5 7.3 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat DUF605 PF04652.11 ETS72884.1 - 4.8 6.4 9.9 5.7 6.2 6.8 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_M18 PF02127.10 ETS72885.1 - 2.8e-165 550.0 0.0 8.5e-165 548.4 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 ETS72885.1 - 1.1e-07 30.8 0.3 0.00015 20.6 0.0 3.0 3 0 0 3 3 3 3 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 ETS72885.1 - 0.072 12.5 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 ArfGap PF01412.13 ETS72886.1 - 2.4 7.9 11.5 2.3 8.0 6.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Plasmodium_Vir PF05795.6 ETS72886.1 - 4.1 6.5 4.3 3.2 6.8 1.6 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Dala_Dala_lig_N PF01820.16 ETS72886.1 - 7 6.9 8.9 27 5.0 6.2 2.0 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus LMBR1 PF04791.11 ETS72886.1 - 8.8 4.7 4.3 15 3.9 3.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Whi5 PF08528.6 ETS72887.1 - 9.5e-05 21.9 0.2 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 Whi5 like HEAT_2 PF13646.1 ETS72888.1 - 7.5e-15 54.9 16.3 0.00048 20.3 0.0 8.0 6 2 2 8 8 8 4 HEAT repeats HEAT PF02985.17 ETS72888.1 - 5.8e-10 38.4 26.1 0.016 15.2 0.0 11.1 12 0 0 12 12 12 3 HEAT repeat Vac14_Fab1_bd PF12755.2 ETS72888.1 - 1.2e-07 32.0 0.0 0.0055 17.0 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETS72888.1 - 2.8e-05 23.5 1.1 1.4 8.1 0.0 5.0 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 ETS72888.1 - 0.00028 21.2 17.8 18 5.9 0.0 9.7 8 0 0 8 8 8 1 HEAT-like repeat Condensin2nSMC PF12422.3 ETS72888.1 - 0.037 13.7 0.9 0.8 9.4 0.1 3.4 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DpnD-PcfM PF14207.1 ETS72888.1 - 0.25 11.1 0.1 0.57 9.9 0.0 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein Transcrip_reg PF01709.15 ETS72889.1 - 5.5e-57 192.5 0.7 6.2e-57 192.4 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator Glyco_transf_22 PF03901.12 ETS72891.1 - 8.4e-62 209.5 22.3 1e-61 209.2 15.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Phosphodiest PF01663.17 ETS72892.1 - 4.7e-18 65.6 0.8 2e-17 63.5 0.6 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS72892.1 - 3.9e-05 22.9 0.0 0.00054 19.2 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 ETS72892.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily RRM_1 PF00076.17 ETS72894.1 - 1.2e-57 191.4 0.1 1.2e-17 63.2 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS72894.1 - 6.5e-46 154.1 0.1 9.8e-14 51.0 0.0 5.9 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS72894.1 - 1.6e-18 66.3 0.0 4.5e-06 26.4 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd3 PF12719.2 ETS72895.1 - 1.9e-93 312.7 3.4 6.2e-93 311.0 0.4 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 ETS72895.1 - 3.3e-10 40.1 16.3 6e-06 26.4 0.9 6.0 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 ETS72895.1 - 1.1e-07 31.2 8.0 0.089 12.9 0.0 7.0 6 1 1 7 7 7 1 HEAT repeat MMS19_N PF14500.1 ETS72895.1 - 0.0013 18.0 0.3 0.18 11.0 0.0 3.4 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 ETS72895.1 - 0.0015 18.9 19.8 0.0036 17.7 1.0 6.7 4 1 3 7 7 7 2 HEAT-like repeat Cohesin_HEAT PF12765.2 ETS72895.1 - 0.028 14.3 1.9 1.2 9.1 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion EGF_2 PF07974.8 ETS72896.1 - 0.0014 18.7 10.6 0.0025 17.9 7.4 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 ETS72896.1 - 0.013 15.5 8.3 0.023 14.7 5.8 1.3 1 0 0 1 1 1 0 EB module p450 PF00067.17 ETS72897.1 - 3.6e-77 259.8 0.0 4.6e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS72898.1 - 5e-14 52.5 0.1 8.5e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS72898.1 - 4.4e-07 29.7 0.1 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS72898.1 - 0.00015 21.6 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS72899.1 - 2.6e-29 102.3 1.5 3.3e-29 101.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS72899.1 - 2.3e-27 96.3 0.1 2.7e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS72899.1 - 1.8e-10 40.8 1.3 6.1e-10 39.0 0.9 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS72899.1 - 0.00037 19.9 0.4 0.0014 18.1 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS72899.1 - 0.0028 17.3 1.0 0.0059 16.3 0.2 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 ETS72899.1 - 0.044 13.3 2.6 0.53 9.8 1.8 2.2 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_35 PF01301.14 ETS72900.1 - 2.4e-68 230.8 1.0 1.7e-67 228.0 0.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS72900.1 - 8.5e-53 178.4 0.0 1.4e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS72900.1 - 1e-36 125.5 2.5 1.3e-18 67.2 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS72900.1 - 1.4e-22 78.8 0.1 3.4e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cys_Met_Meta_PP PF01053.15 ETS72901.1 - 1.6e-57 194.5 0.0 4e-57 193.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Polysacc_deac_1 PF01522.16 ETS72902.1 - 7e-27 93.5 0.0 9.8e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1510 PF07423.6 ETS72902.1 - 0.11 11.8 0.9 0.19 11.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Glyco_hydro_3_C PF01915.17 ETS72903.1 - 4.9e-41 140.7 0.0 1.1e-40 139.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS72903.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Sporozoite_P67 PF05642.6 ETS72903.1 - 0.021 12.6 5.8 0.023 12.5 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_3 PF00933.16 ETS72904.1 - 8.2e-51 172.7 0.0 1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CorA PF01544.13 ETS72906.1 - 0.017 14.1 7.1 0.0093 15.0 2.5 2.3 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein APH PF01636.18 ETS72907.1 - 6.6e-05 22.7 0.5 0.03 14.0 0.2 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 ETS72907.1 - 0.019 14.1 0.0 2 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein kinase domain Pkinase_Tyr PF07714.12 ETS72907.1 - 0.11 11.5 0.0 6.4 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 ETS72908.1 - 4.1e-85 285.3 0.0 5.9e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS72908.1 - 2.5e-49 167.8 0.5 2.9e-48 164.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS72908.1 - 8.1e-24 83.3 0.1 1.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_16 PF00722.16 ETS72910.1 - 1.3e-11 44.0 0.0 1.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 ETS72910.1 - 1.8e-06 26.3 0.5 0.0079 14.4 0.5 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WD40 PF00400.27 ETS72912.1 - 1.1e-24 85.3 9.7 1.7e-06 27.6 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETS72912.1 - 0.00084 17.6 1.3 0.00084 17.6 0.9 2.7 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Cyclin_N PF00134.18 ETS72912.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HA2 PF04408.18 ETS72913.1 - 6.4e-26 90.3 0.0 2.3e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS72913.1 - 4.8e-24 84.3 0.0 1.8e-23 82.4 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETS72913.1 - 3.6e-12 45.9 0.0 9.3e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS72913.1 - 3.8e-08 33.0 0.4 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS72913.1 - 2.4e-05 24.4 0.1 6.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 ETS72913.1 - 0.00064 19.5 2.3 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 ETS72913.1 - 0.00069 19.1 0.2 0.0017 17.8 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 ETS72913.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 ETS72913.1 - 0.0023 16.9 0.0 0.0023 16.9 0.0 1.6 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 ETS72913.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain KaiC PF06745.8 ETS72913.1 - 0.0059 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.1 ETS72913.1 - 0.012 15.9 0.3 0.1 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 ETS72913.1 - 0.015 14.1 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 ETS72913.1 - 0.018 14.9 0.2 0.16 11.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS72913.1 - 0.044 14.0 0.1 0.24 11.6 0.0 2.4 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 ETS72913.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 ETS72913.1 - 0.056 13.0 0.1 0.79 9.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 ETS72913.1 - 0.071 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS72913.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Glycos_transf_2 PF00535.21 ETS72914.1 - 9.9e-33 113.1 0.0 1.2e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETS72914.1 - 2.3e-13 50.4 0.0 3.8e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 ETS72914.1 - 2.7e-08 33.2 0.0 3.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS72914.1 - 0.00066 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 adh_short PF00106.20 ETS72915.1 - 2.2e-32 112.2 1.2 3.1e-32 111.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS72915.1 - 3.5e-27 95.7 0.2 7.8e-27 94.5 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS72915.1 - 3.5e-15 56.1 0.2 4.9e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 ETS72915.1 - 0.026 14.3 0.5 0.041 13.7 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 ETS72915.1 - 0.03 13.9 0.6 0.049 13.2 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS72915.1 - 0.078 12.1 0.2 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SAC3_GANP PF03399.11 ETS72916.1 - 0.00031 20.3 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 ETS72916.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF3944 PF13099.1 ETS72916.1 - 0.1 12.0 0.2 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Shadoo PF14999.1 ETS72916.1 - 1.1 9.0 4.5 2.2 8.1 3.0 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Gly-rich_Ago1 PF12764.2 ETS72916.1 - 3.7 8.2 10.0 3.2 8.4 1.6 2.2 2 0 0 2 2 2 0 Glycine-rich region of argonaut Transp_cyt_pur PF02133.10 ETS72917.1 - 2.2e-73 247.2 45.8 2.6e-73 247.0 31.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Flavin_Reduct PF01613.13 ETS72918.1 - 5.1e-21 75.1 0.5 7.9e-21 74.5 0.3 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Asr PF06392.6 ETS72918.1 - 0.39 11.1 5.5 0.77 10.1 3.8 1.5 1 0 0 1 1 1 0 Acid shock protein repeat DUF1749 PF08538.5 ETS72920.1 - 4.5e-97 324.5 0.0 5.3e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 ETS72920.1 - 2.9e-05 23.7 0.1 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 ETS72920.1 - 0.0005 20.0 1.0 0.00084 19.2 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS72920.1 - 0.026 14.2 0.0 0.1 12.3 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 ETS72920.1 - 0.068 12.5 0.0 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 ETS72920.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) XPA_C PF05181.7 ETS72920.1 - 0.12 11.9 0.1 0.37 10.3 0.1 1.7 1 0 0 1 1 1 0 XPA protein C-terminus MFS_1 PF07690.11 ETS72921.1 - 2.6e-19 69.1 56.5 6.5e-18 64.5 36.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 ETS72922.1 - 1.3e-42 145.7 56.2 1.3e-42 145.7 39.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS72922.1 - 3.2e-20 71.8 19.7 5.3e-20 71.1 13.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS72922.1 - 2.2e-18 66.0 5.9 2.2e-18 66.0 4.1 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter Ank_2 PF12796.2 ETS72923.1 - 6.7e-25 87.2 6.3 2.5e-12 46.9 0.1 5.5 5 1 1 6 6 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS72923.1 - 1.6e-15 55.6 3.9 0.001 19.1 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 ETS72923.1 - 1.7e-15 56.6 7.8 1.5e-06 28.2 0.0 6.3 4 2 3 7 7 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS72923.1 - 1.7e-14 53.8 7.6 6.4e-06 26.5 0.1 7.1 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 ETS72923.1 - 1e-12 47.1 5.7 0.00018 21.1 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.7 ETS72923.1 - 6.2e-10 38.9 0.1 1.7e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS72923.1 - 5.2e-05 23.3 3.0 0.00021 21.3 0.2 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS72923.1 - 8.2e-05 22.7 0.1 0.00062 19.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS72923.1 - 0.0007 19.8 0.0 0.0026 17.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETS72923.1 - 0.0019 18.3 0.1 0.016 15.3 0.0 2.6 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.1 ETS72923.1 - 0.016 14.5 0.0 0.055 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS72923.1 - 0.019 15.7 0.0 0.081 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS72923.1 - 0.024 14.3 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 ETS72923.1 - 0.05 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS72923.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 adh_short PF00106.20 ETS72924.1 - 4.1e-15 56.0 0.1 6.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS72924.1 - 2.3e-08 33.8 0.1 3.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS72924.1 - 0.00049 19.6 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.19 ETS72925.1 - 5.9e-41 140.5 0.0 8.7e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Sigma70_r1_2 PF00140.15 ETS72925.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 FAD_binding_3 PF01494.14 ETS72926.1 - 2e-11 43.5 1.1 3.1e-10 39.6 0.3 2.9 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 ETS72926.1 - 4.5e-08 32.3 0.0 1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS72926.1 - 3.5e-07 29.4 3.4 0.00015 20.7 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS72926.1 - 9.4e-07 28.9 0.3 1.6e-05 24.9 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS72926.1 - 4.5e-05 23.3 0.1 0.00041 20.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS72926.1 - 5.6e-05 21.9 0.3 0.085 11.4 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.22 ETS72926.1 - 9.7e-05 22.6 0.1 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS72926.1 - 9.8e-05 21.5 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS72926.1 - 0.00019 20.0 0.1 0.0027 16.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS72926.1 - 0.00076 18.5 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS72926.1 - 0.00096 19.2 0.0 0.0033 17.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS72926.1 - 0.0023 16.8 0.0 0.02 13.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS72926.1 - 0.0054 16.5 0.4 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 ETS72926.1 - 0.04 13.4 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETS72926.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 ETS72927.1 - 2.2e-34 118.7 30.1 3.4e-34 118.1 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.3 ETS72927.1 - 0.011 15.3 0.5 0.045 13.4 0.1 2.1 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus DUF4131 PF13567.1 ETS72927.1 - 1.8 7.9 13.6 3.5 7.0 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Histidinol_dh PF00815.15 ETS72928.1 - 1.3e-118 396.2 0.3 1.6e-118 395.9 0.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Peptidase_S8 PF00082.17 ETS72929.1 - 4.4e-52 176.9 0.0 1.7e-51 175.0 0.0 2.0 2 1 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 ETS72929.1 - 6.3e-06 26.5 0.0 3.7e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 ETS72929.1 - 0.0022 17.6 0.0 0.0059 16.2 0.0 1.7 1 0 0 1 1 1 1 PA domain UCH PF00443.24 ETS72931.1 - 4.6e-42 143.9 0.0 6.9e-36 123.7 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS72931.1 - 8.8e-17 61.4 0.0 3e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GCC2_GCC3 PF07699.8 ETS72931.1 - 0.62 9.6 3.2 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 F_bP_aldolase PF01116.15 ETS72932.1 - 1.2e-96 323.2 0.0 1.4e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 ETS72932.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase C26 Glyco_hydro_35 PF01301.14 ETS72933.1 - 3.9e-86 289.2 0.0 5.2e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS72933.1 - 2.9e-59 199.4 6.9 4.8e-59 198.7 4.8 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS72933.1 - 1.2e-46 157.5 11.3 5.6e-26 90.9 1.0 4.1 4 1 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS72933.1 - 3e-16 58.5 0.3 1.2e-15 56.6 0.2 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 DUF3994 PF13159.1 ETS72934.1 - 0.0022 18.2 1.1 0.0059 16.8 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3994) Pkinase PF00069.20 ETS72935.1 - 2.2e-56 190.8 0.1 2.8e-39 134.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS72935.1 - 3.4e-26 91.8 0.1 2.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS72935.1 - 7.2e-05 21.8 0.0 0.00014 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS72935.1 - 0.00025 20.8 0.2 0.017 14.8 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS72935.1 - 0.00058 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 ETS72935.1 - 0.039 12.7 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 ETS72935.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 ETS72935.1 - 0.48 9.7 4.1 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 ETS72936.1 - 8.1e-06 25.8 1.0 1.5e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 ETS72936.1 - 0.055 12.7 0.9 0.098 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Spectrin PF00435.16 ETS72938.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat MotB_plug PF13677.1 ETS72938.1 - 0.38 10.1 1.7 0.94 8.8 1.2 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB ketoacyl-synt PF00109.21 ETS72939.1 - 3.6e-81 272.3 0.0 6.6e-81 271.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 ETS72939.1 - 1.1e-77 261.2 0.1 1.7e-77 260.6 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 ETS72939.1 - 1.6e-57 194.0 1.1 3.8e-57 192.8 0.1 2.3 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 ETS72939.1 - 5.7e-49 166.2 0.6 5.7e-49 166.2 0.4 3.0 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 ETS72939.1 - 2.5e-47 161.4 1.4 5.9e-47 160.2 0.9 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 ETS72939.1 - 8e-40 135.3 1.5 1.8e-39 134.2 1.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 ETS72939.1 - 1.2e-38 133.2 1.0 2.8e-38 132.0 0.7 1.5 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 ETS72939.1 - 2.3e-17 64.0 0.0 9.9e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain AMP-binding_C PF13193.1 ETS72939.1 - 4.4e-14 53.1 0.3 6.1e-13 49.5 0.1 3.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 ETS72939.1 - 3e-11 43.4 0.3 4e-07 30.2 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS72939.1 - 1.8e-07 30.4 0.1 3.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 ETS72939.1 - 0.00035 20.3 0.3 0.2 11.4 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family FlgN PF05130.7 ETS72939.1 - 0.12 12.6 0.2 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 FlgN protein Sucrose_synth PF00862.14 ETS72939.1 - 0.76 7.6 0.0 1.3 6.9 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase Sugar_tr PF00083.19 ETS72940.1 - 2.2e-91 306.6 21.1 2.5e-91 306.5 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS72940.1 - 8.9e-22 77.2 21.6 8.9e-22 77.2 15.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS72940.1 - 1.4e-05 23.5 0.8 2.4e-05 22.7 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 ETS72940.1 - 0.12 12.4 4.3 0.2 11.7 2.0 2.1 1 1 0 1 1 1 0 Phage holin family 2 DUF2530 PF10745.4 ETS72940.1 - 3.4 7.6 7.0 0.35 10.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Lyase_1 PF00206.15 ETS72941.1 - 9.7e-49 166.2 0.0 2.7e-48 164.7 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 ETS72941.1 - 5.2e-21 74.4 0.0 1.6e-19 69.6 0.0 2.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF2680 PF10925.3 ETS72941.1 - 0.042 13.7 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Fungal_trans PF04082.13 ETS72942.1 - 1.1e-22 80.1 1.1 1.8e-22 79.4 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS72942.1 - 9e-09 35.1 9.0 1.7e-08 34.2 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.7 ETS72943.1 - 2.7e-22 79.1 0.0 3.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 ETS72944.1 - 4.4e-87 292.8 6.7 5.4e-87 292.5 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 ETS72945.1 - 4.5e-07 28.8 0.0 5e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Poly_export PF02563.11 ETS72945.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein VirE3 PF06661.6 ETS72945.1 - 0.023 13.8 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 VirE3 Mpv17_PMP22 PF04117.7 ETS72946.1 - 5.4e-24 83.6 0.2 1.9e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 ETS72947.1 - 9.5e-154 511.5 0.4 1.1e-153 511.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 ETS72947.1 - 0.13 12.5 1.3 8.5 6.7 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain DSS1_SEM1 PF05160.8 ETS72948.1 - 1.2e-21 76.2 18.8 1.2e-20 73.0 13.0 2.0 1 1 0 1 1 1 1 DSS1/SEM1 family Rhamno_transf PF11316.3 ETS72948.1 - 0.098 11.8 0.2 0.13 11.4 0.1 1.2 1 1 0 1 1 1 0 Putative rhamnosyl transferase Cwf_Cwc_15 PF04889.7 ETS72948.1 - 1.6 8.3 11.8 1.7 8.2 8.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3808 PF10300.4 ETS72949.1 - 1.2e-121 406.5 0.0 1.4e-121 406.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 ETS72949.1 - 0.00037 20.7 0.2 0.031 14.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS72949.1 - 0.0013 18.4 0.3 0.0089 15.8 0.2 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS72949.1 - 0.0031 17.4 0.2 0.013 15.4 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS72949.1 - 0.0055 16.5 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS72949.1 - 0.011 16.2 3.3 0.042 14.4 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS72949.1 - 0.06 13.7 0.1 0.5 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS72949.1 - 0.35 10.5 2.6 0.45 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP_N PF01213.14 ETS72950.1 - 3.6e-37 128.3 0.0 4.1e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal RB_B PF01857.15 ETS72950.1 - 0.067 12.6 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain RPW8 PF05659.6 ETS72950.1 - 0.097 12.2 0.0 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3237 PF11578.3 ETS72951.1 - 4.9e-32 110.3 0.0 5.5e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.11 ETS72952.1 - 5.6e-37 127.2 20.3 5.6e-37 127.2 14.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS72952.1 - 2e-06 26.7 35.8 6.9e-06 24.8 22.2 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 ETS72953.1 - 2.1e-33 115.3 3.0 3.1e-33 114.7 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 ETS72954.1 - 1.4e-115 386.2 0.1 1.7e-115 385.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Flt3_lig PF02947.9 ETS72954.1 - 0.0061 16.4 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 1 flt3 ligand YbjQ_1 PF01906.12 ETS72954.1 - 0.099 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative heavy-metal-binding RPE65 PF03055.10 ETS72955.1 - 1.3e-137 459.2 0.0 1.5e-137 459.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3824 PF12868.2 ETS72956.1 - 0.14 13.0 1.0 0.16 12.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ATP-synt_E PF05680.7 ETS72956.1 - 0.23 11.4 3.5 0.39 10.6 2.5 1.5 1 1 0 1 1 1 0 ATP synthase E chain Aldo_ket_red PF00248.16 ETS72957.1 - 2.7e-39 134.7 0.0 1.3e-37 129.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Saccharop_dh PF03435.13 ETS72957.1 - 0.13 11.2 0.0 0.75 8.7 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase HIT PF01230.18 ETS72958.1 - 2.1e-16 60.2 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETS72958.1 - 1.7e-07 31.4 0.0 2.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ETS72958.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.8 ETS72959.1 - 3.8e-15 55.0 7.9 5e-15 54.6 5.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 ETS72959.1 - 0.0006 19.4 0.2 0.00068 19.2 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ETS72959.1 - 0.012 15.4 1.0 0.016 14.9 0.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 ETS72959.1 - 0.028 14.2 0.3 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 ETS72959.1 - 0.065 12.7 2.8 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain FYDLN_acid PF09538.5 ETS72959.1 - 0.093 13.3 0.3 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-dskA_traR PF01258.12 ETS72959.1 - 0.13 12.0 4.8 0.2 11.4 3.3 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger GFA PF04828.9 ETS72959.1 - 0.15 12.0 1.7 5.3 7.0 1.2 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 ETS72959.1 - 0.52 9.6 7.0 1.1 8.5 4.8 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 ETS72959.1 - 8.9 6.6 7.7 6.7 7.0 0.2 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain ATP_bind_1 PF03029.12 ETS72960.1 - 1.9e-75 253.5 0.0 2.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 ETS72960.1 - 8.2e-05 22.7 0.0 0.00027 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 ETS72960.1 - 0.00013 20.8 0.1 0.068 11.9 0.0 2.3 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 ETS72960.1 - 0.00025 20.5 0.0 0.025 14.0 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS72960.1 - 0.00026 20.9 0.1 0.0009 19.1 0.0 2.0 2 1 0 2 2 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS72960.1 - 0.0012 19.3 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 ETS72960.1 - 0.0022 18.8 1.0 0.0058 17.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS72960.1 - 0.0023 17.9 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETS72960.1 - 0.0024 17.7 0.2 0.0046 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 ETS72960.1 - 0.0042 16.5 0.4 0.014 14.9 0.3 1.9 1 1 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.7 ETS72960.1 - 0.0045 16.1 0.6 0.0083 15.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 ETS72960.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.13 ETS72960.1 - 0.006 15.8 0.0 0.16 11.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B NB-ARC PF00931.17 ETS72960.1 - 0.0064 15.3 0.2 0.016 14.0 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.13 ETS72960.1 - 0.016 14.7 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 ETS72960.1 - 0.017 14.5 0.0 0.045 13.2 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 ETS72960.1 - 0.02 14.1 0.0 0.8 8.9 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_30 PF13604.1 ETS72960.1 - 0.026 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETS72960.1 - 0.035 13.5 0.0 0.53 9.7 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 ETS72960.1 - 0.038 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS72960.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 ETS72960.1 - 0.11 11.8 0.8 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.1 ETS72960.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.6 2 1 1 3 3 2 0 AAA domain AAA_23 PF13476.1 ETS72960.1 - 0.51 10.6 3.3 6 7.1 2.3 2.1 1 1 0 1 1 1 0 AAA domain Daxx PF03344.10 ETS72960.1 - 0.56 8.6 11.8 0.75 8.2 8.2 1.1 1 0 0 1 1 1 0 Daxx Family BTB PF00651.26 ETS72962.1 - 5e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 ETS72962.1 - 0.0088 16.1 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Peptidase_S24 PF00717.18 ETS72964.1 - 6.6e-07 28.8 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like CwfJ_C_1 PF04677.10 ETS72965.1 - 8.2e-31 106.1 0.0 1.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 ETS72965.1 - 6.2e-23 81.1 0.1 1.9e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 TFIIB PF00382.14 ETS72966.1 - 6.7e-30 102.7 0.0 5.7e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 ETS72966.1 - 1.7e-20 73.0 0.3 1.7e-20 73.0 0.2 3.5 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 ETS72966.1 - 0.00051 19.6 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Bac_rhamnosid PF05592.6 ETS72967.1 - 8.7e-23 80.2 0.0 8e-20 70.5 0.0 2.6 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS72967.1 - 2e-06 26.7 0.0 4.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Nucleos_tra2_C PF07662.8 ETS72968.1 - 1.1e-68 230.8 2.8 1.1e-68 230.8 2.0 2.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 ETS72968.1 - 7.1e-23 80.7 5.2 7.1e-23 80.7 3.6 2.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 ETS72968.1 - 0.012 15.5 7.0 0.012 15.5 4.9 3.9 4 0 0 4 4 4 0 Nucleoside recognition NADH-u_ox-rdase PF10785.4 ETS72968.1 - 0.018 15.2 0.1 0.076 13.2 0.1 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TauD PF02668.11 ETS72969.1 - 1.5e-43 149.3 0.1 1.9e-43 149.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.6 ETS72969.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) UQ_con PF00179.21 ETS72970.1 - 1.1e-42 144.7 0.0 1.2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS72970.1 - 8.1e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS72970.1 - 0.00076 19.3 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 RWD domain RabGAP-TBC PF00566.13 ETS72971.1 - 5.8e-37 127.2 0.0 2e-33 115.6 0.0 2.6 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Transketolase_N PF00456.16 ETS72971.1 - 0.041 12.6 0.1 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Excalibur PF05901.6 ETS72973.1 - 0.11 12.8 1.2 5.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Excalibur calcium-binding domain DEAD PF00270.24 ETS72974.1 - 3e-47 160.2 0.0 4.8e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS72974.1 - 6.7e-26 89.9 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS72974.1 - 0.00024 21.0 0.1 0.0024 17.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Daxx PF03344.10 ETS72974.1 - 0.1 11.0 14.4 0.14 10.5 10.0 1.1 1 0 0 1 1 1 0 Daxx Family ORC6 PF05460.8 ETS72974.1 - 0.17 10.9 7.7 0.26 10.3 5.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.7 ETS72974.1 - 1.1 7.1 12.9 1.5 6.6 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS72974.1 - 3.1 5.7 10.5 4.6 5.1 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Brix PF04427.13 ETS72975.1 - 1.6e-54 184.5 0.0 2.2e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2681 PF10883.3 ETS72975.1 - 0.035 14.2 3.7 0.086 13.0 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PBP_sp32 PF07222.7 ETS72975.1 - 9.2 5.3 8.4 24 3.9 5.8 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF791 PF05631.9 ETS72976.1 - 2.7e-47 161.2 4.4 3.9e-47 160.6 1.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETS72976.1 - 1.4e-19 70.0 22.3 6.9e-19 67.7 11.9 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS72976.1 - 9.3e-06 25.3 0.1 0.00094 18.9 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 ETS72976.1 - 6.3e-05 21.7 4.2 6.3e-05 21.7 2.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS72976.1 - 0.0025 16.2 0.8 0.0025 16.2 0.5 3.3 3 1 0 3 3 3 1 MFS/sugar transport protein HsbA PF12296.3 ETS72977.1 - 3.5e-22 78.5 7.9 4.5e-22 78.2 5.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FA_hydroxylase PF04116.8 ETS72978.1 - 1.3e-06 28.7 8.0 1.3e-06 28.7 5.5 2.6 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Abhydrolase_6 PF12697.2 ETS72979.1 - 2.6e-21 76.5 0.4 1.6e-20 74.0 0.3 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS72979.1 - 3.9e-09 36.4 0.0 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS72979.1 - 2.8e-07 30.3 0.0 1.3e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 ETS72979.1 - 0.22 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family GST_N_3 PF13417.1 ETS72980.1 - 4.5e-07 30.0 0.0 1.2e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS72980.1 - 1.4e-05 24.8 3.1 1.8e-05 24.5 0.7 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS72980.1 - 0.0019 18.1 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS72980.1 - 0.0042 17.5 0.2 0.0083 16.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CD34_antigen PF06365.7 ETS72981.1 - 0.00047 19.8 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family Protocadherin PF08374.6 ETS72981.1 - 0.00055 19.6 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 ETS72981.1 - 0.00084 19.6 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.13 ETS72981.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.1 ETS72981.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.5 2 0 0 2 2 2 1 TMEM154 protein family DUF1191 PF06697.7 ETS72981.1 - 0.0017 17.2 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF1049 PF06305.6 ETS72981.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Adeno_E3_CR2 PF02439.10 ETS72981.1 - 0.014 14.9 0.3 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3084 PF11283.3 ETS72981.1 - 0.016 15.0 0.4 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) DUF3377 PF11857.3 ETS72981.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Syndecan PF01034.15 ETS72981.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 ETS72981.1 - 0.051 11.8 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 ETS72981.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF3357 PF11837.3 ETS72981.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SKG6 PF08693.5 ETS72981.1 - 0.14 11.4 3.2 0.24 10.7 2.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GNVR PF13807.1 ETS72981.1 - 0.15 11.8 0.7 3.2 7.5 0.3 2.2 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Pex14_N PF04695.8 ETS72982.1 - 0.03 14.3 4.2 0.042 13.8 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 ETS72982.1 - 0.41 9.9 5.7 0.45 9.8 4.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF3149 PF11346.3 ETS72982.1 - 0.67 9.5 3.2 1.2 8.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) EBA-175_VI PF11556.3 ETS72982.1 - 0.9 9.6 4.2 1.6 8.8 2.9 1.3 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 Amidoligase_2 PF12224.3 ETS72983.1 - 7.9e-13 48.5 0.3 1.7e-08 34.3 0.0 2.7 2 1 0 2 2 2 2 Putative amidoligase enzyme Zn_clus PF00172.13 ETS72984.1 - 2.9e-08 33.4 10.9 4.7e-08 32.8 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain JAB PF01398.16 ETS72986.1 - 7.8e-09 35.2 0.1 3.2e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 ETS72986.1 - 0.084 12.0 0.5 6.6 5.8 0.1 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal AdoHcyase PF05221.12 ETS72987.1 - 1.7e-137 456.7 0.1 1.9e-137 456.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 ETS72987.1 - 8e-84 279.4 2.4 1.4e-83 278.6 1.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS72987.1 - 1.1e-06 27.9 0.5 2.8e-06 26.6 0.2 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 ETS72987.1 - 0.0079 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 ETS72987.1 - 0.022 14.1 0.5 0.043 13.1 0.4 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 ETS72988.1 - 3.2e-55 186.0 0.0 4.3e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS72988.1 - 3.5e-18 65.3 0.0 4.1e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS72988.1 - 9.3e-06 25.5 0.0 2.6e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 ETS72989.1 - 5.2e-80 269.2 29.2 6.3e-80 268.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS72989.1 - 1.9e-34 118.9 55.7 3.8e-33 114.6 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS72989.1 - 1.6e-09 36.6 26.0 3.6e-05 22.3 5.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 ETS72989.1 - 0.00049 18.3 4.5 0.00049 18.3 3.1 2.9 2 1 1 3 3 3 2 Transmembrane secretion effector TRI12 PF06609.8 ETS72989.1 - 0.001 17.3 2.4 0.001 17.3 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 ETS72989.1 - 0.011 15.4 1.8 0.12 12.2 0.1 2.9 2 1 0 2 2 2 0 MFS_1 like family Mito_carr PF00153.22 ETS72990.1 - 2.9e-46 155.1 2.4 2.2e-19 68.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ChAPs PF09295.5 ETS72991.1 - 2.9e-156 520.2 0.0 4e-156 519.7 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 ETS72991.1 - 2.8e-07 30.5 0.2 0.39 11.4 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS72991.1 - 4.1e-06 26.1 0.4 0.18 11.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS72991.1 - 4.7e-06 25.9 0.1 0.058 13.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS72991.1 - 6.1e-06 25.7 1.3 0.014 15.2 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS72991.1 - 9.3e-06 25.2 1.1 0.0019 17.7 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.1 ETS72991.1 - 0.00074 19.4 1.0 17 5.4 0.2 4.5 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS72991.1 - 0.00082 18.8 0.1 0.29 10.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS72991.1 - 0.0032 18.1 0.0 5.9 7.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS72991.1 - 0.0062 16.8 0.1 0.18 12.1 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS72991.1 - 0.021 14.6 0.1 11 6.0 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS72991.1 - 0.027 14.9 0.1 24 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2007 PF09413.5 ETS72991.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) PPR_3 PF13812.1 ETS72991.1 - 0.085 13.1 0.0 40 4.8 0.0 3.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_11 PF13414.1 ETS72992.1 - 2.2e-06 27.1 2.3 0.11 12.2 0.2 5.1 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 ETS72992.1 - 0.003 17.6 0.4 19 5.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS72992.1 - 0.36 11.5 6.9 13 6.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.13 ETS72993.1 - 9.1e-12 44.3 2.5 1.1e-11 44.0 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_N_3 PF13417.1 ETS72994.1 - 3.2e-11 43.2 0.0 5.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS72994.1 - 7.5e-11 41.8 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS72994.1 - 2.4e-10 40.2 0.0 4.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS72994.1 - 5.2e-08 32.9 0.0 2.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS72994.1 - 0.00041 20.1 0.1 0.00096 18.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS72994.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 ETS72995.1 - 1.6e-58 198.3 0.0 1.8e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.16 ETS72996.1 - 2.8e-10 39.7 0.8 1.2e-09 37.6 0.6 2.0 1 1 0 1 1 1 1 Dioxygenase AA_permease PF00324.16 ETS72997.1 - 7.5e-114 380.6 44.3 9.3e-114 380.3 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS72997.1 - 7e-36 123.6 49.0 9.6e-36 123.2 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_2 PF03446.10 ETS72998.1 - 2.2e-29 102.4 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS72998.1 - 2.7e-23 82.3 0.0 4.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh_N PF03721.9 ETS72998.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETS72998.1 - 0.066 13.4 0.2 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF970 PF06153.6 ETS72998.1 - 0.11 12.5 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF970) Aldedh PF00171.17 ETS72999.1 - 2.5e-175 583.2 0.1 2.8e-175 583.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_polI_A14 PF08203.6 ETS72999.1 - 0.12 12.6 0.2 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 DUF1993 PF09351.5 ETS73000.1 - 1.7e-46 158.0 0.0 1.9e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) YjcZ PF13990.1 ETS73000.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein E1-E2_ATPase PF00122.15 ETS73001.1 - 6.8e-61 205.2 6.7 6.3e-60 202.0 3.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS73001.1 - 1e-31 109.8 3.3 1e-31 109.8 2.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS73001.1 - 2.3e-29 103.3 0.0 9.1e-28 98.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS73001.1 - 4e-15 55.0 0.1 1.2e-14 53.5 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 ETS73001.1 - 1.2e-14 54.0 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS73001.1 - 7.1e-13 49.1 1.4 1.8e-12 47.8 1.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS73001.1 - 2e-07 30.8 1.4 6.9e-06 25.8 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SID-1_RNA_chan PF13965.1 ETS73001.1 - 0.047 11.8 2.6 0.25 9.4 0.2 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 2TM PF13239.1 ETS73001.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.6 3 0 0 3 3 3 0 2TM domain Amidohydro_3 PF07969.6 ETS73002.1 - 1.3e-56 192.5 2.4 1.7e-56 192.2 1.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS73002.1 - 1.2e-07 31.4 0.1 5.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS73002.1 - 0.00014 21.6 0.3 0.21 11.2 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 ETS73002.1 - 0.0063 16.5 4.5 0.012 15.7 0.0 2.7 2 1 0 2 2 2 1 Amidohydrolase Lactamase_B_2 PF12706.2 ETS73003.1 - 4.4e-24 85.1 0.0 5.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS73003.1 - 2.8e-12 46.6 0.0 3.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS73003.1 - 0.033 13.8 0.9 0.069 12.8 0.6 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily SprT-like PF10263.4 ETS73005.1 - 1.9e-05 24.3 0.1 3.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 SprT-like family DUF3633 PF12315.3 ETS73005.1 - 0.0017 17.7 0.3 0.0028 16.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) Phage_portal_2 PF05136.8 ETS73006.1 - 0.0096 14.4 2.6 0.012 14.2 1.8 1.0 1 0 0 1 1 1 1 Phage portal protein, lambda family DUF3060 PF11259.3 ETS73006.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) Glyco_hydro_30 PF02055.11 ETS73007.1 - 5.9e-45 153.3 6.2 7.7e-45 153.0 4.3 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 ETS73007.1 - 0.0008 18.4 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 BTB PF00651.26 ETS73008.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain UQ_con PF00179.21 ETS73009.1 - 2.7e-26 91.6 0.0 3.7e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 ETS73010.1 - 6.2e-41 140.9 0.2 8.1e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Surface antigen MFS_1 PF07690.11 ETS73011.1 - 1.8e-22 79.5 33.7 1.8e-22 79.5 23.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73011.1 - 1.6e-12 46.8 3.5 1.6e-12 46.8 2.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter IATP PF04568.7 ETS73012.1 - 0.0073 16.3 3.2 0.0073 16.3 2.2 1.8 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP adh_short PF00106.20 ETS73013.1 - 2.9e-16 59.8 1.4 1e-15 58.0 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73013.1 - 6.1e-06 26.1 0.0 9.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73013.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS73013.1 - 0.0023 17.6 0.4 0.0067 16.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 ETS73013.1 - 0.003 17.2 0.4 0.015 15.0 0.3 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS73013.1 - 0.034 14.1 0.2 0.064 13.2 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF2567 PF10821.3 ETS73014.1 - 0.25 10.8 5.8 0.073 12.5 1.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2567) DUF1705 PF08019.7 ETS73014.1 - 5.2 6.5 17.4 0.11 11.9 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) ADH_N PF08240.7 ETS73015.1 - 1.1e-08 34.7 0.4 4.8e-08 32.7 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73015.1 - 1.8e-07 30.7 0.9 3.8e-07 29.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 ETS73016.1 - 2e-18 66.8 0.0 1.2e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS73016.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ETS73016.1 - 0.028 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETS73016.1 - 0.04 13.9 0.4 0.89 9.5 0.3 2.6 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 ETS73016.1 - 0.091 11.4 0.1 0.17 10.5 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Apolipoprotein PF01442.13 ETS73017.1 - 0.027 13.9 0.2 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FMO-like PF00743.14 ETS73018.1 - 1.3e-26 92.9 0.0 1.5e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS73018.1 - 3.8e-18 66.3 0.1 2.8e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS73018.1 - 1.6e-06 28.1 0.0 0.00033 20.5 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS73018.1 - 1.6e-06 27.2 1.2 0.03 13.2 0.0 3.4 3 1 1 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS73018.1 - 3.8e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS73018.1 - 5.8e-05 22.9 0.2 0.0019 17.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS73018.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS73018.1 - 0.15 10.4 0.2 0.25 9.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Saccharop_dh PF03435.13 ETS73019.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFS_1 PF07690.11 ETS73020.1 - 3.9e-24 85.0 54.3 7.6e-21 74.2 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 ETS73021.1 - 3.9e-58 197.2 0.0 5.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS73021.1 - 1.1e-06 27.8 0.5 0.00099 18.0 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS73021.1 - 2.7e-05 22.8 0.3 9.6e-05 21.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 ETS73021.1 - 9.4e-05 21.6 0.2 0.00019 20.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS73021.1 - 0.00021 20.2 0.1 0.0005 19.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS73021.1 - 0.00066 19.6 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS73021.1 - 0.0014 18.6 0.1 0.0038 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS73021.1 - 0.0015 17.5 0.4 0.024 13.5 0.2 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 ETS73021.1 - 0.002 16.8 0.0 0.0045 15.6 0.0 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 ETS73021.1 - 0.0062 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS73021.1 - 0.042 13.9 0.1 0.18 11.8 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS73021.1 - 0.05 14.0 1.3 0.15 12.4 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DIT1_PvcA PF05141.7 ETS73022.1 - 6.9e-86 288.0 0.0 9.4e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 ETS73022.1 - 2.1e-26 93.1 0.0 8.4e-26 91.1 0.0 2.0 3 0 0 3 3 3 1 Taurine catabolism dioxygenase TauD, TfdA family Epimerase PF01370.16 ETS73023.1 - 7.8e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73023.1 - 2.4e-10 40.7 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS73023.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 ETS73023.1 - 0.0033 16.3 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 ETS73023.1 - 0.0033 17.3 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 ETS73023.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 ETS73023.1 - 0.066 11.9 0.0 0.2 10.3 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 ETS73024.1 - 1.2e-29 102.9 0.0 1.6e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73024.1 - 3.5e-08 33.1 6.7 5.8e-08 32.5 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 ETS73025.1 - 5.9e-25 88.3 0.0 7.5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 ETS73026.1 - 1.6e-44 152.1 0.0 2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 ETS73027.1 - 6.3e-18 65.5 0.0 1.7e-17 64.1 0.0 1.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS73027.1 - 8.2e-11 40.7 0.0 1.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS73027.1 - 7.4e-09 34.9 0.1 3.1e-06 26.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS73027.1 - 9.3e-05 22.3 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS73027.1 - 0.0019 17.1 0.0 0.0072 15.2 0.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 ETS73027.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETS73027.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 ETS73028.1 - 1.8e-26 93.0 0.0 3.8e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73028.1 - 4.2e-10 39.5 0.0 1.7e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS73028.1 - 4e-05 23.1 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS73028.1 - 0.0012 17.5 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS73028.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS73028.1 - 0.028 14.1 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PCNA_N PF00705.13 ETS73028.1 - 0.054 13.0 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Polysacc_synt_2 PF02719.10 ETS73028.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.8 ETS73029.1 - 2.4e-24 86.1 0.0 3.2e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS73029.1 - 1.9e-12 46.4 0.0 2.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS73029.1 - 0.0014 18.4 0.1 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS73029.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_12 PF01670.11 ETS73030.1 - 3.5e-17 62.6 0.4 6.6e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Med3 PF11593.3 ETS73030.1 - 1.7 7.8 15.4 2.1 7.4 10.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Claudin_2 PF13903.1 ETS73031.1 - 0.0018 17.9 0.9 0.24 11.0 0.2 2.4 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Melittin PF01372.12 ETS73031.1 - 0.084 12.2 0.2 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Melittin Bestrophin PF01062.16 ETS73031.1 - 2.1 7.1 7.1 0.34 9.7 1.3 2.2 3 1 0 3 3 3 0 Bestrophin, RFP-TM, chloride channel Glyco_hydro_3 PF00933.16 ETS73032.1 - 1.5e-76 257.2 0.0 2.6e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS73032.1 - 9.8e-59 198.6 0.0 1.6e-58 197.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS73032.1 - 3e-19 68.7 0.0 6.3e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS73032.1 - 2.1e-06 27.4 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Tnp_DNA_bind PF14706.1 ETS73032.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Transposase DNA-binding Sugar_tr PF00083.19 ETS73033.1 - 3.9e-74 249.8 29.9 4.6e-74 249.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73033.1 - 6.4e-17 61.3 39.6 1.9e-16 59.7 22.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS73034.1 - 0.00023 20.1 2.6 0.00095 18.1 1.8 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.9 ETS73035.1 - 4.7e-71 239.0 1.3 5.3e-71 238.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GCIP PF13324.1 ETS73036.1 - 3.3e-06 26.5 0.7 8.5e-06 25.1 0.5 1.6 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Fungal_trans_2 PF11951.3 ETS73036.1 - 0.021 13.4 0.0 0.042 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain EcoR124_C PF12008.3 ETS73036.1 - 0.038 13.1 3.9 0.69 9.0 1.2 2.3 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal SPOC PF07744.8 ETS73037.1 - 4.1e-14 53.0 0.0 8.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 ETS73037.1 - 8e-13 48.4 2.3 8e-13 48.4 1.6 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 ETS73037.1 - 1.7e-08 34.0 8.4 3.1e-08 33.1 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-XS PF03470.9 ETS73037.1 - 0.029 14.4 0.6 0.13 12.3 0.4 2.1 1 0 0 1 1 1 0 XS zinc finger domain Proteasome PF00227.21 ETS73038.1 - 2.2e-60 203.1 0.1 2.7e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS73038.1 - 2.8e-14 52.1 0.2 6.9e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 ETS73038.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit NTP_transferase PF00483.18 ETS73039.1 - 2.3e-28 99.1 0.0 2.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 ETS73039.1 - 1.5e-10 40.0 4.4 2.8e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 ETS73039.1 - 1.6e-06 28.3 0.0 2.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 ETS73039.1 - 0.014 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.7 ETS73039.1 - 0.087 11.3 0.0 0.41 9.1 0.0 1.9 2 0 0 2 2 2 0 L-fucokinase Hexapep_2 PF14602.1 ETS73039.1 - 0.14 11.7 1.0 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Peptidase_M54 PF07998.6 ETS73040.1 - 5.2e-10 39.4 0.2 9.2e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.19 ETS73040.1 - 0.00095 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin PF01421.14 ETS73040.1 - 0.02 14.4 1.9 0.039 13.5 1.3 1.5 1 1 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M57 PF12388.3 ETS73040.1 - 0.023 14.0 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Endonuclease_1 PF04231.8 ETS73040.1 - 0.027 14.3 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease I Reprolysin_3 PF13582.1 ETS73040.1 - 0.032 14.7 0.2 0.054 14.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 ETS73040.1 - 0.037 12.5 0.9 0.058 11.8 0.7 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.1 ETS73040.1 - 0.072 13.0 1.0 0.14 12.0 0.7 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ETS73040.1 - 0.082 12.9 0.5 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 ETS73040.1 - 0.15 10.8 0.4 0.24 10.2 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 FAA_hydrolase PF01557.13 ETS73041.1 - 4.3e-51 173.4 0.0 6e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETS73041.1 - 2.1e-28 98.4 0.1 3.5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 ETS73042.1 - 1.1e-16 60.5 0.1 2.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73042.1 - 1.5e-07 31.2 12.5 2.8e-07 30.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 ETS73042.1 - 0.24 11.1 1.6 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit COG5 PF10392.4 ETS73042.1 - 1.5 8.7 5.3 18 5.2 0.1 3.5 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Arylesterase PF01731.15 ETS73043.1 - 0.036 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Methyltransf_23 PF13489.1 ETS73045.1 - 8.6e-07 28.8 0.0 2.8e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73045.1 - 5.3e-06 26.8 0.0 9.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73045.1 - 0.00012 22.6 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS73045.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS73045.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS73045.1 - 0.003 17.5 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73045.1 - 0.0032 17.9 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73045.1 - 0.0073 16.6 0.0 0.017 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain ketoacyl-synt PF00109.21 ETS73046.1 - 7e-74 248.5 0.2 1.7e-73 247.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS73046.1 - 1e-48 165.3 0.0 5.4e-48 163.0 0.0 2.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 ETS73046.1 - 3.1e-45 154.9 0.1 7.6e-45 153.6 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 ETS73046.1 - 4.1e-44 150.9 0.0 7.5e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS73046.1 - 2.2e-39 135.0 0.0 1.1e-38 132.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS73046.1 - 2.6e-38 130.5 0.2 8.5e-38 128.8 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS73046.1 - 6.6e-16 58.5 0.0 1.8e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS73046.1 - 9.8e-14 51.3 0.0 2.7e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73046.1 - 2.5e-11 44.1 0.0 1.1e-10 42.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73046.1 - 3.4e-09 36.4 0.0 6.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73046.1 - 9.3e-09 35.6 0.0 4.3e-08 33.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS73046.1 - 5.5e-06 25.6 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 ETS73046.1 - 0.00016 21.8 0.1 0.00044 20.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS73046.1 - 0.00023 20.2 0.1 0.00046 19.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 ETS73046.1 - 0.0092 15.4 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase ACP_syn_III PF08545.5 ETS73046.1 - 0.026 14.1 0.3 0.076 12.6 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MTS PF05175.9 ETS73046.1 - 0.029 13.7 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain ThiF PF00899.16 ETS73046.1 - 0.18 11.6 0.8 0.85 9.4 0.3 2.4 2 0 0 2 2 2 0 ThiF family DUF3129 PF11327.3 ETS73048.1 - 1.2e-35 122.9 14.9 1.6e-35 122.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) ADH_zinc_N PF00107.21 ETS73049.1 - 2.3e-29 101.5 2.0 3.9e-29 100.8 1.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS73049.1 - 1.9e-28 98.4 1.5 3.3e-28 97.6 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS73049.1 - 1.2e-19 71.4 0.5 2.8e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 ETS73049.1 - 0.009 15.9 0.9 0.021 14.7 0.6 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS73049.1 - 0.014 15.3 0.7 0.038 14.0 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 ETS73049.1 - 0.094 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DegV PF02645.11 ETS73049.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 ELFV_dehydrog PF00208.16 ETS73049.1 - 0.3 10.6 2.7 0.29 10.6 0.9 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PBP1_TM PF14812.1 ETS73050.1 - 0.4 11.0 1.8 0.62 10.4 1.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3659 PF12396.3 ETS73053.1 - 5e-16 58.1 6.4 8.3e-11 41.4 3.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF3659 PF12396.3 ETS73054.1 - 1.5e-164 533.8 114.1 4.5e-24 83.9 0.4 12.2 11 2 1 12 12 12 9 Protein of unknown function (DUF3659) Apolipoprotein PF01442.13 ETS73054.1 - 0.0012 18.3 0.0 0.007 15.8 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.5 ETS73054.1 - 0.017 15.0 0.1 2 8.5 0.1 3.2 2 1 0 2 2 2 0 Phasin protein DUF883 PF05957.8 ETS73054.1 - 0.022 15.1 11.7 0.77 10.1 0.1 4.9 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) MCP_N PF05581.7 ETS73054.1 - 0.33 11.1 6.1 12 6.0 0.1 4.1 1 1 4 5 5 5 0 Vibrio chemotaxis protein N terminus PGAP1 PF07819.8 ETS73055.1 - 1.9e-05 24.3 0.0 9.5e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS73055.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS73055.1 - 0.00061 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETS73055.1 - 0.0042 16.4 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 ETS73055.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PY_rept_46 PF09689.5 ETS73055.1 - 0.27 11.6 2.5 12 6.2 0.1 3.1 3 0 0 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) Chlorosome_CsmC PF11098.3 ETS73056.1 - 0.83 9.3 10.8 1.4 8.6 7.5 1.4 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF4175 PF13779.1 ETS73056.1 - 3.1 5.3 4.5 3.5 5.1 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Acetyltransf_1 PF00583.19 ETS73057.1 - 1.2e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS73057.1 - 0.0055 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box PF00646.28 ETS73058.1 - 9.7e-05 21.9 0.0 0.00027 20.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 ETS73058.1 - 0.00027 20.6 3.2 0.00044 19.9 1.0 2.2 2 2 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 ETS73058.1 - 0.00048 19.7 0.6 0.00098 18.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like CBM-like PF14683.1 ETS73060.1 - 4.1e-40 137.1 0.4 9.1e-40 136.0 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 ETS73060.1 - 2e-21 75.9 1.0 5.9e-21 74.3 0.7 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 ETS73060.1 - 6.5e-07 29.3 1.5 2.1e-06 27.6 1.0 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 ETS73060.1 - 0.00025 21.1 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) phage_tail_N PF08400.5 ETS73060.1 - 0.025 14.2 0.2 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Cu_amine_oxid PF01179.15 ETS73061.1 - 1e-168 561.3 0.0 1.3e-168 561.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS73061.1 - 2.2e-21 75.7 0.9 3.8e-21 75.0 0.1 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 ETS73061.1 - 1.3e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.7 ETS73061.1 - 0.28 10.1 0.0 0.48 9.3 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC p450 PF00067.17 ETS73062.1 - 8.2e-61 205.9 0.0 1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS73063.1 - 6e-16 58.8 0.6 6e-16 58.8 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73063.1 - 1.2e-08 35.0 0.3 1.9e-08 34.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73063.1 - 1.5e-05 24.7 0.4 2.4e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS73063.1 - 0.00087 18.7 0.4 0.0014 18.0 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73063.1 - 0.058 13.3 0.6 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS73063.1 - 0.093 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETS73063.1 - 0.34 10.7 2.0 0.57 10.0 0.2 2.2 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HgmA PF04209.8 ETS73064.1 - 4.3e-175 582.1 0.1 5e-175 581.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAD_binding_3 PF01494.14 ETS73065.1 - 2.2e-15 56.6 0.0 4.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS73065.1 - 0.011 14.6 0.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApoLp-III PF07464.6 ETS73066.1 - 3.9e-05 23.7 1.4 8e-05 22.6 1.0 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF3552 PF12072.3 ETS73066.1 - 0.00029 20.1 5.8 0.00029 20.1 4.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF2359 PF10151.4 ETS73066.1 - 0.0009 17.8 0.1 0.0013 17.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) FlaC_arch PF05377.6 ETS73066.1 - 0.0021 17.8 2.0 0.5 10.2 1.1 2.8 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) DUF4375 PF14300.1 ETS73066.1 - 0.0022 17.9 1.5 0.0058 16.6 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4375) DUF1664 PF07889.7 ETS73066.1 - 0.0046 16.7 1.0 0.017 14.9 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Prominin PF05478.6 ETS73066.1 - 0.0054 14.3 0.8 0.0054 14.3 0.5 2.0 1 1 1 2 2 2 1 Prominin DUF948 PF06103.6 ETS73066.1 - 0.0067 16.2 1.7 0.065 13.1 1.1 2.5 3 0 0 3 3 2 1 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 ETS73066.1 - 0.0075 16.6 2.5 0.043 14.2 0.7 2.4 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF883 PF05957.8 ETS73066.1 - 0.0077 16.6 3.1 0.03 14.7 2.2 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Carbpep_Y_N PF05388.6 ETS73066.1 - 0.0095 16.0 0.2 0.021 14.9 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Filament PF00038.16 ETS73066.1 - 0.014 14.8 1.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein PqqD PF05402.7 ETS73066.1 - 0.019 14.9 0.6 0.047 13.6 0.1 1.9 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Phage_GP20 PF06810.6 ETS73066.1 - 0.023 14.1 1.6 0.023 14.1 1.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2884 PF11101.3 ETS73066.1 - 0.025 13.9 0.6 0.025 13.9 0.4 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2884) Rifin_STEVOR PF02009.11 ETS73066.1 - 0.028 14.0 0.3 0.041 13.5 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family NAAA-beta PF15508.1 ETS73066.1 - 0.031 14.6 1.0 0.75 10.1 0.3 2.8 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2305 PF10230.4 ETS73066.1 - 0.035 13.5 2.7 0.045 13.1 1.0 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Phasin PF05597.6 ETS73066.1 - 0.036 13.8 5.6 0.023 14.4 2.0 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) UPF0150 PF03681.10 ETS73066.1 - 0.037 13.6 0.1 0.081 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Sec8_exocyst PF04048.9 ETS73066.1 - 0.039 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Apolipoprotein PF01442.13 ETS73066.1 - 0.04 13.4 0.1 0.083 12.3 0.0 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Activator-TraM PF11657.3 ETS73066.1 - 0.046 13.2 3.5 0.073 12.5 2.4 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM GP41 PF00517.12 ETS73066.1 - 0.046 13.2 1.5 0.072 12.6 0.6 1.6 2 0 0 2 2 1 0 Retroviral envelope protein DUF2229 PF09989.4 ETS73066.1 - 0.099 12.0 0.4 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FIVAR PF07554.8 ETS73066.1 - 0.1 12.8 1.6 0.19 11.9 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain PEP-utilisers_N PF05524.8 ETS73066.1 - 0.1 12.3 1.6 0.5 10.1 1.1 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal ISG65-75 PF11727.3 ETS73066.1 - 0.11 11.5 3.9 0.19 10.7 2.7 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein THOC7 PF05615.8 ETS73066.1 - 0.13 12.5 1.5 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.17 ETS73066.1 - 0.15 12.1 4.6 0.41 10.6 0.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3359 PF11839.3 ETS73066.1 - 0.15 12.4 2.0 1.1 9.6 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) LEA_1 PF03760.10 ETS73066.1 - 0.17 12.0 8.6 0.33 11.1 6.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 KfrA_N PF11740.3 ETS73066.1 - 0.29 11.5 7.1 0.13 12.7 2.0 2.3 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term YtxH PF12732.2 ETS73066.1 - 0.35 11.2 8.1 2.3 8.6 5.6 2.2 1 1 0 1 1 1 0 YtxH-like protein DUF4618 PF15397.1 ETS73066.1 - 0.37 10.0 4.0 0.82 8.9 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) ARGLU PF15346.1 ETS73066.1 - 0.44 10.3 6.3 0.058 13.1 0.6 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Prefoldin_2 PF01920.15 ETS73066.1 - 0.68 9.7 5.9 0.31 10.7 1.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit Osmo_CC PF08946.5 ETS73066.1 - 0.84 9.7 4.1 1.3 9.0 1.4 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1451 PF07295.6 ETS73066.1 - 1.4 8.7 4.4 0.52 10.0 1.4 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1451) Prefoldin PF02996.12 ETS73066.1 - 1.6 8.3 6.2 0.85 9.2 2.5 1.8 2 0 0 2 2 2 0 Prefoldin subunit Bap31 PF05529.7 ETS73066.1 - 4.8 6.5 6.7 43 3.4 0.0 2.5 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like DUF2634 PF10934.3 ETS73067.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) HJURP_mid PF12346.3 ETS73067.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat Abhydrolase_6 PF12697.2 ETS73068.1 - 6.1e-23 81.8 0.1 7.9e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73068.1 - 1.3e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73068.1 - 9e-10 38.4 0.1 2.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS73068.1 - 1.9e-05 24.9 0.2 3.3e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 ETS73068.1 - 0.0074 15.9 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase MRP-L28 PF09812.4 ETS73068.1 - 0.019 14.8 2.9 0.029 14.1 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 FRG1 PF06229.7 ETS73068.1 - 0.11 11.8 0.6 0.17 11.3 0.4 1.2 1 0 0 1 1 1 0 FRG1-like family zf-SNAP50_C PF12251.3 ETS73068.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal PGAP1 PF07819.8 ETS73068.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein AT_hook PF02178.14 ETS73069.1 - 0.0021 17.5 19.4 0.18 11.5 4.8 2.7 2 0 0 2 2 2 2 AT hook motif MRP-L20 PF12824.2 ETS73069.1 - 2 8.3 8.5 1 9.3 4.2 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 TPR_MLP1_2 PF07926.7 ETS73071.1 - 1.2e-27 96.2 26.9 1.2e-27 96.2 18.7 18.2 4 3 11 15 15 15 3 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 ETS73071.1 - 0.00029 20.7 6.8 0.00029 20.7 4.7 22.4 9 6 12 22 22 22 2 Centrosome localisation domain of PPC89 WEMBL PF05701.6 ETS73071.1 - 0.0008 17.9 19.9 0.0008 17.9 13.8 11.9 5 4 5 10 10 10 4 Weak chloroplast movement under blue light SlyX PF04102.7 ETS73071.1 - 0.0027 18.0 2.0 0.0027 18.0 1.4 20.7 16 7 5 21 21 21 2 SlyX Spectrin PF00435.16 ETS73071.1 - 0.0033 17.7 8.7 0.0033 17.7 6.0 19.6 6 4 16 23 23 23 1 Spectrin repeat DcpS_C PF11969.3 ETS73072.1 - 1.4e-05 25.2 0.3 0.055 13.7 0.1 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding SLBP_RNA_bind PF15247.1 ETS73072.1 - 0.039 13.7 1.3 0.039 13.7 0.9 2.1 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain Zn_clus PF00172.13 ETS73073.1 - 0.00028 20.7 5.3 0.00053 19.8 3.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS73073.1 - 0.00079 18.1 0.8 0.0051 15.4 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 ETS73074.1 - 6.9e-92 308.0 0.0 8e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.17 ETS73075.1 - 6.9e-67 225.9 0.0 8.3e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 ETS73076.1 - 2.1e-30 105.5 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS73076.1 - 4.3e-27 94.1 0.0 4e-26 91.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 ETS73076.1 - 1.8e-24 85.2 0.2 3.1e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 ETS73076.1 - 1.8e-05 24.7 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS73076.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Gram_pos_anchor PF00746.16 ETS73076.1 - 4.2 7.3 7.2 6.2 6.7 0.2 2.6 2 0 0 2 2 2 0 Gram positive anchor Lyase_1 PF00206.15 ETS73077.1 - 4e-24 85.3 0.1 8.5e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Lyase ASL_C2 PF14698.1 ETS73077.1 - 4.9e-09 36.1 0.2 2.6e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Baculo_PEP_C PF04513.7 ETS73077.1 - 0.057 13.2 0.3 7.1 6.4 0.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nbl1_Borealin_N PF10444.4 ETS73077.1 - 0.082 12.2 0.0 2.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Syntaxin_2 PF14523.1 ETS73077.1 - 0.11 12.5 0.1 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Big_3_4 PF13754.1 ETS73078.1 - 0.062 13.6 4.1 0.11 12.8 0.5 2.8 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Aldo_ket_red PF00248.16 ETS73079.1 - 5e-55 186.3 0.0 6.5e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Actin PF00022.14 ETS73081.1 - 7.1e-101 337.4 0.0 8.3e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETS73081.1 - 0.034 12.7 0.0 0.73 8.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein UFD1 PF03152.9 ETS73083.1 - 4e-25 87.9 0.0 4.1e-20 71.6 0.0 2.8 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 PRP21_like_P PF12230.3 ETS73083.1 - 0.34 10.3 3.4 1.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-H2C2_5 PF13909.1 ETS73083.1 - 7.5 6.9 9.4 0.62 10.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Glyco_hydro_35 PF01301.14 ETS73084.1 - 1.8e-81 273.9 0.0 1.8e-81 273.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS73084.1 - 3.9e-59 199.0 2.6 6.5e-59 198.3 1.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS73084.1 - 1.2e-41 141.4 9.5 1.7e-23 82.9 1.0 3.6 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS73084.1 - 2.5e-20 71.6 0.0 8.6e-20 69.9 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 GCR1_C PF12550.3 ETS73086.1 - 5.9e-23 80.5 1.8 1.1e-22 79.6 1.2 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Baculo_PEP_C PF04513.7 ETS73086.1 - 0.023 14.5 1.5 0.035 13.9 1.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LOH1CR12 PF10158.4 ETS73086.1 - 0.13 12.0 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Tumour suppressor protein DUF3493 PF11998.3 ETS73090.1 - 0.079 12.8 1.5 9.5 6.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Pribosyltran PF00156.22 ETS73091.1 - 6e-09 35.6 0.4 5.4e-08 32.6 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Lipase_GDSL_2 PF13472.1 ETS73092.1 - 1.1e-17 64.7 0.7 1.1e-17 64.7 0.5 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS73092.1 - 1.5e-10 41.3 5.4 1.5e-10 41.3 3.7 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase DAHP_synth_1 PF00793.15 ETS73093.1 - 5.9e-99 330.1 0.1 7.4e-99 329.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.4 ETS73095.1 - 4.4e-15 55.6 0.0 8.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF1987 PF09345.5 ETS73095.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Abhydrolase_6 PF12697.2 ETS73096.1 - 1.9e-28 99.8 1.9 2.3e-28 99.6 1.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73096.1 - 4.4e-09 36.2 0.2 2.8e-07 30.3 0.2 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS73096.1 - 6.2e-09 35.7 0.1 1.8e-08 34.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS73096.1 - 3.1e-06 26.9 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase MFS_1 PF07690.11 ETS73097.1 - 1.1e-28 99.9 29.3 1.1e-28 99.9 20.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS73097.1 - 0.89 9.0 14.4 0.031 13.7 4.2 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PTR2 PF00854.16 ETS73098.1 - 1.8e-25 89.5 1.8 5e-12 45.2 2.2 2.4 1 1 0 2 2 2 2 POT family LAMTOR PF15454.1 ETS73099.1 - 4.8e-16 58.8 0.5 9.3e-16 57.8 0.3 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF1311 PF07007.7 ETS73099.1 - 0.061 13.4 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) Cmc1 PF08583.5 ETS73100.1 - 0.0083 15.8 1.2 3.1 7.6 0.1 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C2H2_jaz PF12171.3 ETS73101.1 - 0.0012 18.9 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS73101.1 - 0.026 14.7 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 ETS73101.1 - 0.036 14.2 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Med7 PF05983.6 ETS73102.1 - 2.1e-53 180.3 0.0 2.5e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 MED7 protein DPM3 PF08285.6 ETS73105.1 - 4.2e-33 113.0 0.2 4.6e-33 112.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.4 ETS73107.1 - 1.3e-24 85.3 6.9 1.3e-24 85.3 4.8 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF605 PF04652.11 ETS73107.1 - 0.46 9.8 18.0 0.11 11.9 9.0 1.9 2 0 0 2 2 2 0 Vta1 like DUF3669 PF12417.3 ETS73108.1 - 2.3e-24 84.8 0.2 6e-24 83.5 0.1 1.7 2 0 0 2 2 2 1 Zinc finger protein ADH_N PF08240.7 ETS73110.1 - 2.8e-24 84.9 2.8 4.7e-24 84.2 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73110.1 - 1.9e-21 75.9 0.0 3.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73110.1 - 3.2e-07 31.2 0.0 5.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS73110.1 - 3.5e-05 23.0 0.1 5.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS73110.1 - 0.034 13.9 0.1 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4241 PF14025.1 ETS73110.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) ELFV_dehydrog PF00208.16 ETS73110.1 - 0.047 13.2 0.1 0.071 12.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CAP PF00188.21 ETS73111.1 - 1e-08 35.6 2.3 1e-08 35.6 1.6 1.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family GRP PF07172.6 ETS73111.1 - 9.6e-05 22.7 1.6 0.00021 21.7 1.1 1.5 1 0 0 1 1 1 1 Glycine rich protein family Acyl_transf_3 PF01757.17 ETS73112.1 - 3.1e-19 68.9 30.0 5.7e-19 68.1 20.8 1.5 1 0 0 1 1 1 1 Acyltransferase family FAD_binding_3 PF01494.14 ETS73113.1 - 2.3e-31 109.1 0.0 3.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS73113.1 - 6.4e-07 28.6 0.1 2.1e-06 26.8 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 ETS73113.1 - 9.5e-07 28.0 3.5 2.4e-05 23.4 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS73113.1 - 9.3e-06 24.9 0.7 0.039 13.0 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS73113.1 - 1.4e-05 25.0 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS73113.1 - 5.8e-05 23.4 0.9 0.00019 21.7 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS73113.1 - 6.3e-05 21.6 0.4 0.0056 15.1 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 ETS73113.1 - 0.00084 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 ETS73113.1 - 0.0019 16.9 0.5 0.0088 14.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 ETS73113.1 - 0.01 14.9 0.2 0.022 13.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 ETS73113.1 - 0.01 16.0 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 ETS73113.1 - 0.022 14.6 0.3 0.05 13.4 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETS73113.1 - 0.048 13.4 0.3 13 5.6 0.0 2.8 2 1 1 3 3 3 0 ThiF family Pyr_redox_3 PF13738.1 ETS73113.1 - 0.054 13.5 0.1 0.086 12.8 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS73113.1 - 0.079 12.5 0.9 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 ETS73113.1 - 0.11 11.3 0.6 0.21 10.3 0.4 1.5 1 1 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 ETS73113.1 - 0.13 11.9 0.3 0.43 10.1 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS73113.1 - 0.18 11.2 2.6 2.2 7.6 0.1 3.1 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA AXE1 PF05448.7 ETS73114.1 - 0.063 11.7 0.0 0.13 10.7 0.0 1.4 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) DUF463 PF04317.7 ETS73114.1 - 0.18 10.3 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Glyco_hydro_61 PF03443.9 ETS73115.1 - 3.1e-44 151.3 0.0 3.9e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.13 ETS73116.1 - 2.1e-08 33.9 7.3 4.6e-08 32.8 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3377 PF11857.3 ETS73116.1 - 0.089 12.4 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2427 PF10348.4 ETS73117.1 - 0.19 11.3 3.7 3.7 7.1 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Sugar_tr PF00083.19 ETS73118.1 - 1e-118 396.7 26.2 1.4e-118 396.3 18.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73118.1 - 1.2e-24 86.7 46.0 1.1e-18 67.0 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 ETS73118.1 - 0.058 13.0 2.3 0.13 11.9 0.3 2.4 2 0 0 2 2 2 0 Lysis protein S Myb_DNA-bind_6 PF13921.1 ETS73119.1 - 1.1e-06 28.6 0.2 3.1e-06 27.1 0.1 1.8 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS73119.1 - 0.0073 16.3 0.1 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.3 ETS73119.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GST_N PF02798.15 ETS73120.1 - 2.8e-11 43.4 0.0 1.1e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS73120.1 - 3.8e-10 39.6 0.0 8.6e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS73120.1 - 3.3e-08 33.3 0.0 7.8e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS73120.1 - 3.1e-06 27.3 0.0 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS73120.1 - 3.3e-06 27.0 0.0 2.3e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS73120.1 - 0.00016 22.0 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UbiA PF01040.13 ETS73121.1 - 2.6e-31 108.7 18.2 3.9e-31 108.2 12.6 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 ETS73121.1 - 0.087 12.8 0.8 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Mito_carr PF00153.22 ETS73121.1 - 0.12 12.0 0.9 9.4 6.0 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein BCS1_N PF08740.6 ETS73122.1 - 9e-31 106.9 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 ETS73122.1 - 1.9e-17 63.7 0.0 7e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS73122.1 - 1.5e-05 24.1 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS73122.1 - 0.00013 22.8 0.0 0.00041 21.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 ETS73122.1 - 0.0036 17.0 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 ETS73122.1 - 0.0057 16.0 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS73122.1 - 0.0092 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETS73122.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 ETS73122.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS73122.1 - 0.021 14.8 0.1 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 ETS73122.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 ETS73122.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Polyoma_lg_T_C PF06431.6 ETS73122.1 - 0.051 12.2 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_18 PF13238.1 ETS73122.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETS73122.1 - 0.076 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 ETS73122.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS73122.1 - 0.14 12.3 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETS73122.1 - 0.19 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Methyltransf_PK PF05891.7 ETS73123.1 - 2e-76 256.1 0.0 2.4e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 ETS73123.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73123.1 - 0.0002 21.7 0.0 0.00035 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SET PF00856.23 ETS73124.1 - 2.7e-10 40.7 0.2 6.3e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 SET domain SET PF00856.23 ETS73125.1 - 0.0071 16.6 0.0 0.0075 16.5 0.0 1.1 1 0 0 1 1 1 1 SET domain Transaldolase PF00923.14 ETS73126.1 - 2.5e-47 161.3 0.0 3.4e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase mRNA_triPase PF02940.10 ETS73128.1 - 1.2e-49 168.9 0.0 1.8e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 ETS73129.1 - 2.6e-42 140.6 18.3 5.4e-08 32.6 0.0 9.5 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 ETS73129.1 - 1.9e-16 60.1 0.0 4.7e-12 46.0 0.0 5.1 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 ETS73129.1 - 2.5e-08 33.2 0.0 2.3 8.5 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 ETS73129.1 - 4.2e-07 30.2 0.2 0.00097 19.5 0.0 4.7 4 1 0 4 4 4 1 HEAT-like repeat Codanin-1_C PF15296.1 ETS73129.1 - 0.025 14.4 0.1 0.088 12.6 0.0 1.9 1 0 0 1 1 1 0 Codanin-1 C-terminus MFS_1 PF07690.11 ETS73130.1 - 1.1e-29 103.2 29.9 7.9e-26 90.5 9.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73130.1 - 2.4e-25 89.0 26.2 2.7e-24 85.5 18.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.11 ETS73130.1 - 0.0032 16.2 0.1 0.0053 15.5 0.1 1.4 1 0 0 1 1 1 1 BT1 family PIRT PF15099.1 ETS73130.1 - 0.071 12.3 0.8 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family NADH_u_ox_C PF12853.2 ETS73130.1 - 0.074 12.7 0.0 8.7 6.1 0.1 2.2 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit HSP70 PF00012.15 ETS73131.1 - 5.2e-05 21.3 0.0 0.00011 20.2 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein Sec8_exocyst PF04048.9 ETS73132.1 - 0.56 9.8 6.2 15 5.2 0.2 3.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Catalase PF00199.14 ETS73133.1 - 2.3e-168 559.8 2.0 2.8e-168 559.5 1.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 ETS73133.1 - 8.7e-16 57.5 0.1 2.4e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive YscO PF07321.7 ETS73133.1 - 0.062 13.1 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO MFS_1 PF07690.11 ETS73134.1 - 2.9e-39 134.8 34.9 2.9e-39 134.8 24.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73134.1 - 8.5e-14 50.9 24.1 1.4e-13 50.2 16.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS73134.1 - 5.1e-10 38.1 0.1 5.1e-10 38.1 0.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Xan_ur_permease PF00860.15 ETS73135.1 - 9.3e-66 221.9 36.9 2.4e-64 217.2 25.6 2.1 1 1 0 1 1 1 1 Permease family Fungal_trans PF04082.13 ETS73136.1 - 1.5e-13 50.1 0.0 2.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73136.1 - 6.3e-05 22.8 12.9 0.00011 21.9 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1314 PF07013.6 ETS73136.1 - 0.032 13.6 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) DHquinase_I PF01487.10 ETS73138.1 - 3.5e-43 147.8 0.0 5.8e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 ETS73138.1 - 2.8e-20 72.1 0.1 6.3e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 ETS73138.1 - 2.2e-13 50.3 0.0 4.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 ETS73138.1 - 7.4e-12 45.5 0.0 1.7e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 ETS73138.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS73138.1 - 0.0072 17.1 0.1 0.022 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 ETS73138.1 - 0.038 14.3 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.12 ETS73138.1 - 0.078 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ABC_tran PF00005.22 ETS73138.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter OCD_Mu_crystall PF02423.10 ETS73138.1 - 0.098 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Saccharop_dh PF03435.13 ETS73138.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_16 PF13191.1 ETS73138.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS73138.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AP_endonuc_2 PF01261.19 ETS73139.1 - 1.9e-28 99.2 0.0 2.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 ETS73140.1 - 1.6e-130 435.6 25.9 1.9e-130 435.4 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73140.1 - 5.7e-26 91.0 33.3 5.7e-26 91.0 23.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 ETS73141.1 - 1.8e-22 79.1 0.0 3.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS73141.1 - 3.3e-16 59.6 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.20 ETS73142.1 - 5.3e-71 239.0 0.0 9e-71 238.3 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 ETS73143.1 - 6.3e-63 210.2 0.2 7.1e-63 210.0 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II WD40 PF00400.27 ETS73144.1 - 5.6e-08 32.3 4.3 0.23 11.4 0.3 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat TFIIA PF03153.8 ETS73144.1 - 0.01 15.7 4.7 0.011 15.6 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apc4_WD40 PF12894.2 ETS73144.1 - 0.067 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.7 ETS73144.1 - 1.5 6.6 15.9 2 6.2 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 ETS73144.1 - 3.7 7.0 10.8 5.6 6.4 7.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 ETS73144.1 - 5.4 4.9 13.8 7.5 4.4 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 ETS73144.1 - 6.2 5.8 15.7 9.1 5.3 10.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Methyltransf_23 PF13489.1 ETS73145.1 - 1.7e-16 60.3 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73145.1 - 6.5e-12 46.0 0.2 2.2e-10 41.1 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73145.1 - 1.1e-09 38.6 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73145.1 - 3e-08 33.3 0.0 4.1e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73145.1 - 1.7e-07 31.6 0.0 2.7e-06 27.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73145.1 - 2.4e-06 27.8 0.0 8.3e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETS73145.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 ETS73145.1 - 0.00042 19.4 0.0 0.00094 18.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 ETS73145.1 - 0.031 13.4 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 ETS73145.1 - 0.034 14.1 0.0 0.19 11.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS73145.1 - 0.037 13.4 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 ETS73145.1 - 0.042 12.9 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 ETS73145.1 - 0.043 12.9 0.0 0.26 10.3 0.0 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Glyco_hydro_18 PF00704.23 ETS73146.1 - 2.8e-44 151.9 0.0 3.4e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MARVEL PF01284.18 ETS73147.1 - 7.4e-19 68.0 23.3 9.3e-19 67.6 16.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4018 PF13210.1 ETS73147.1 - 0.024 14.0 4.0 0.032 13.5 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Cupin_2 PF07883.6 ETS73148.1 - 3.2e-10 39.3 0.1 4.3e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.7 ETS73148.1 - 0.00021 20.8 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 ETS73148.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS73148.1 - 0.0088 15.7 0.0 0.0097 15.5 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 ETS73148.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Peptidase_A4 PF01828.12 ETS73149.1 - 5.1e-87 290.3 14.3 6.1e-87 290.0 9.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family Pam16 PF03656.8 ETS73149.1 - 0.054 13.3 2.3 0.054 13.2 0.5 1.8 2 0 0 2 2 2 0 Pam16 Peptidase_A4 PF01828.12 ETS73150.1 - 2.8e-81 271.5 10.2 3.4e-81 271.2 7.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family CBM_4_9 PF02018.12 ETS73150.1 - 0.21 11.5 4.5 1.5 8.8 0.1 3.2 2 1 1 3 3 3 0 Carbohydrate binding domain Bac_rhamnosid PF05592.6 ETS73151.1 - 7.8e-23 80.4 0.1 2.7e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 ETS73151.1 - 1.8e-08 34.0 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF1769 PF08588.5 ETS73153.1 - 4.7e-30 103.3 0.4 1.1e-29 102.1 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3506 PF12014.3 ETS73154.1 - 5.5e-39 133.0 0.0 8.9e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 ETS73154.1 - 7.8e-07 28.7 0.1 3.3e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS73154.1 - 1.5e-05 24.5 0.2 1.5e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.6 ETS73155.1 - 7e-09 35.0 0.0 1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS73155.1 - 0.008 15.6 0.0 0.0092 15.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Abhydrolase_6 PF12697.2 ETS73156.1 - 2e-13 50.7 0.5 3.7e-13 49.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73156.1 - 8.2e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73156.1 - 0.00048 19.7 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peroxidase_2 PF01328.12 ETS73157.1 - 2.6e-13 49.3 1.3 2.8e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Peroxidase, family 2 Unstab_antitox PF09720.5 ETS73157.1 - 0.042 13.5 0.6 0.08 12.6 0.4 1.4 1 0 0 1 1 1 0 Putative addiction module component Sugar_tr PF00083.19 ETS73158.1 - 2.8e-71 240.4 13.4 3.2e-71 240.2 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73158.1 - 4.1e-31 107.9 29.8 4.5e-24 84.8 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS73158.1 - 0.00035 18.9 0.8 0.00035 18.9 0.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 ETS73158.1 - 0.0016 17.2 3.0 0.0039 15.9 2.1 1.6 1 0 0 1 1 1 1 PUCC protein MFS_1_like PF12832.2 ETS73158.1 - 0.0047 16.6 0.3 0.097 12.4 0.0 3.0 2 1 1 3 3 3 1 MFS_1 like family DUF2850 PF11012.3 ETS73159.1 - 0.025 14.7 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) GATase PF00117.23 ETS73160.1 - 7.2e-06 25.5 0.2 8.7e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I AA_permease_2 PF13520.1 ETS73161.1 - 2.3e-51 174.7 50.9 2.8e-51 174.3 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS73161.1 - 9.5e-22 76.9 45.5 1.4e-21 76.4 31.5 1.2 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.1 ETS73161.1 - 1.5 6.8 7.8 0.06 11.5 1.1 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 HATPase_c PF02518.21 ETS73162.1 - 2.2e-23 82.0 0.0 4.6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS73162.1 - 1.3e-21 76.6 0.4 2.6e-21 75.7 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 ETS73162.1 - 7.4e-12 45.5 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 ETS73162.1 - 3.6e-09 36.6 0.0 9.5e-08 32.0 0.0 2.7 2 0 0 2 2 2 1 PAS fold HisKA PF00512.20 ETS73162.1 - 1.1e-06 28.5 3.4 1.2e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 ETS73162.1 - 7.7e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 ETS73162.1 - 6.7e-05 22.5 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 ETS73162.1 - 0.019 14.6 0.0 0.085 12.5 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.1 ETS73162.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 GAF domain PAS_7 PF12860.2 ETS73162.1 - 0.079 12.9 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 PAS fold Beta-lactamase PF00144.19 ETS73164.1 - 8.9e-19 67.6 0.3 1.2e-18 67.2 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Sulfatase PF00884.18 ETS73165.1 - 2e-45 155.3 0.2 2.7e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS73165.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Abhydrolase_6 PF12697.2 ETS73166.1 - 2.1e-31 109.5 0.0 2.4e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73166.1 - 8.2e-16 58.2 0.0 1.6e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS73166.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS73166.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Iso_dh PF00180.15 ETS73167.1 - 9e-99 330.7 0.0 1.4e-98 330.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.14 ETS73169.1 - 2.5e-20 72.6 0.0 3.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 GLTT PF01744.15 ETS73170.1 - 6.8e-05 22.1 0.5 0.00016 21.0 0.2 1.7 2 0 0 2 2 2 1 GLTT repeat (6 copies) CR6_interact PF10147.4 ETS73171.1 - 0.0057 15.9 4.0 0.014 14.7 2.8 1.6 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Herpes_gE PF02480.11 ETS73171.1 - 0.052 11.8 0.0 0.082 11.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Polyketide_cyc2 PF10604.4 ETS73173.1 - 1.1e-11 45.0 0.1 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ETS73173.1 - 0.049 13.6 1.1 0.072 13.0 0.5 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.18 ETS73175.1 - 1.3e-13 50.6 0.2 3.2e-13 49.3 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS73175.1 - 8.1e-09 35.2 1.1 2.6e-08 33.6 0.7 1.9 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS73175.1 - 0.2 10.7 0.2 0.3 10.1 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aa_trans PF01490.13 ETS73176.1 - 1e-77 261.3 27.9 1.2e-77 261.1 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NIF3 PF01784.13 ETS73178.1 - 4.6e-05 23.1 0.0 7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RPEL PF02755.10 ETS73179.1 - 4.9e-19 67.0 2.9 1.4e-09 36.9 0.2 2.5 2 0 0 2 2 2 2 RPEL repeat Microtub_bind PF13931.1 ETS73179.1 - 0.14 12.2 2.9 0.18 11.9 2.0 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding DUF4267 PF14087.1 ETS73180.1 - 2.7e-11 43.0 3.9 3.4e-11 42.7 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3318 PF11780.3 ETS73180.1 - 4.5 6.8 7.1 1.2 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3318) E1-E2_ATPase PF00122.15 ETS73181.1 - 1.1e-63 214.4 3.2 1.8e-63 213.6 2.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS73181.1 - 6.7e-31 108.3 0.0 2.5e-26 93.4 0.0 2.4 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 ETS73181.1 - 1.1e-29 103.2 6.9 1.1e-29 103.2 4.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 ETS73181.1 - 1.1e-17 63.8 0.0 3.4e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 ETS73181.1 - 4.1e-15 54.9 0.0 9.2e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS73181.1 - 7.8e-14 52.2 0.0 1.7e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS73181.1 - 2e-05 24.2 0.3 0.00088 18.9 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pilus_PilP PF11356.3 ETS73181.1 - 0.068 13.4 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Type IV pilus biogenesis Sugar_tr PF00083.19 ETS73182.1 - 5.6e-130 433.9 26.5 6.3e-130 433.7 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73182.1 - 7.8e-23 80.7 51.1 7e-20 71.0 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MutS_V PF00488.16 ETS73183.1 - 3e-78 262.4 0.0 5e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS73183.1 - 7.1e-49 166.3 0.0 1.9e-48 164.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETS73183.1 - 2.1e-32 111.5 0.0 4.3e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 ETS73183.1 - 8.8e-15 54.6 1.3 2.2e-14 53.3 0.9 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 ETS73183.1 - 5.1e-14 52.4 2.1 6.8e-14 52.1 0.0 2.4 3 0 0 3 3 3 1 MutS domain II AAA_29 PF13555.1 ETS73183.1 - 0.03 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Shugoshin_C PF07557.6 ETS73183.1 - 5.7 6.5 10.3 0.27 10.7 0.5 2.6 2 0 0 2 2 2 0 Shugoshin C terminus NmrA PF05368.8 ETS73184.1 - 1.3e-41 142.3 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS73184.1 - 1.7e-10 41.2 0.1 2.3e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 ETS73184.1 - 0.0084 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Ribosomal_S28e PF01200.13 ETS73184.1 - 0.043 13.5 0.2 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S28e adh_short PF00106.20 ETS73184.1 - 0.057 13.3 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sial-lect-inser PF09264.5 ETS73184.1 - 0.068 12.4 0.3 0.097 11.9 0.2 1.2 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Semialdhyde_dh PF01118.19 ETS73184.1 - 0.076 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS73185.1 - 1.2e-22 80.5 0.4 6.9e-22 78.1 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73185.1 - 1.7e-09 37.8 0.0 1.8e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73185.1 - 1.5e-08 34.4 0.2 2.7e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 ETS73185.1 - 0.014 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 ETS73185.1 - 0.11 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G_glu_transpept PF01019.16 ETS73187.1 - 6.5e-158 526.3 0.4 7.5e-158 526.1 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fungal_trans PF04082.13 ETS73188.1 - 3.5e-17 62.1 0.0 2.6e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Melibiase PF02065.13 ETS73189.1 - 0.049 12.3 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Melibiase p450 PF00067.17 ETS73190.1 - 2.8e-45 154.7 0.0 5.2e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.9 ETS73191.1 - 3.5e-68 229.7 13.4 3.8e-57 193.5 3.7 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 ETS73191.1 - 1.9e-11 43.8 3.6 2.1e-05 24.0 0.0 3.2 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_16 PF00722.16 ETS73192.1 - 4.2e-33 114.1 5.1 4.2e-33 114.1 3.5 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 ETS73192.1 - 1.7e-05 24.6 14.1 3.1e-05 23.8 9.8 1.4 1 0 0 1 1 1 1 Chitin recognition protein GAS PF13851.1 ETS73193.1 - 0.0081 15.3 0.5 0.0081 15.3 0.3 2.4 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 ETS73193.1 - 5.5 6.6 6.9 12 5.4 0.4 3.2 2 1 1 3 3 3 0 Mnd1 family PK PF00224.16 ETS73194.1 - 1e-167 557.1 7.3 1.3e-167 556.7 5.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 ETS73194.1 - 5.5e-30 103.3 0.0 1.9e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 ETS73194.1 - 3.1e-05 22.9 0.4 0.0001 21.2 0.2 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Aldedh PF00171.17 ETS73195.1 - 6.5e-147 489.5 0.0 7.7e-147 489.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.2 ETS73196.1 - 3.1e-23 81.9 0.2 1.9e-08 34.5 0.0 5.5 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS73196.1 - 2.7e-19 67.9 9.1 0.00014 21.4 0.0 7.4 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 ETS73196.1 - 5.2e-14 51.9 5.7 7.6e-05 22.8 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS73196.1 - 3.5e-12 46.4 0.3 0.013 15.9 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73196.1 - 1e-11 43.8 4.9 0.54 10.6 0.0 7.8 7 1 0 7 7 7 3 Ankyrin repeat F-box PF00646.28 ETS73196.1 - 0.042 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF924 PF06041.6 ETS73197.1 - 1.6e-15 57.3 0.0 4.1e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) AA_permease_2 PF13520.1 ETS73198.1 - 2.6e-76 256.8 23.6 3.3e-76 256.5 16.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS73198.1 - 1e-13 50.5 19.5 1.8e-13 49.7 13.5 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3040 PF11239.3 ETS73198.1 - 6.2 6.9 10.9 0.82 9.7 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Myelin-PO_C PF10570.4 ETS73199.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.8 1 1 1 2 2 2 0 Myelin-PO cytoplasmic C-term p65 binding region p450 PF00067.17 ETS73200.1 - 3.6e-53 180.7 0.0 5.1e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 ETS73200.1 - 0.0084 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Reticulon Methyltransf_23 PF13489.1 ETS73201.1 - 3.9e-18 65.6 0.0 8.5e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73201.1 - 4.2e-11 43.1 0.0 8.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73201.1 - 1.3e-10 41.8 0.1 2.6e-09 37.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73201.1 - 8.2e-10 38.4 0.0 1.4e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73201.1 - 1.2e-07 32.0 0.0 1.1e-06 29.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73201.1 - 0.0014 18.9 0.0 0.0049 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETS73201.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 ETS73201.1 - 0.0076 15.4 0.0 0.018 14.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 ETS73201.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS73201.1 - 0.042 13.8 0.2 0.51 10.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 ETS73201.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF3129 PF11327.3 ETS73202.1 - 4.4e-42 143.9 13.4 5.9e-42 143.5 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PA14_2 PF10528.4 ETS73202.1 - 0.15 12.0 1.2 0.44 10.5 0.0 2.1 1 1 0 2 2 2 0 GLEYA domain Zn_clus PF00172.13 ETS73204.1 - 1.6e-19 69.5 25.5 1e-09 38.1 6.4 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73204.1 - 1.8e-16 59.8 1.3 2.9e-16 59.1 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.17 ETS73205.1 - 2.5e-105 353.0 1.3 3.2e-105 352.6 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3336 PF11815.3 ETS73206.1 - 7.6e-42 142.2 0.5 2.1e-41 140.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 ETS73206.1 - 6.6e-22 78.4 0.7 5e-21 75.5 0.0 2.6 3 0 0 3 3 3 1 Patatin-like phospholipase PBP1_TM PF14812.1 ETS73206.1 - 0.74 10.1 9.9 3.4 8.0 1.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 ETS73207.1 - 4.7e-08 33.1 3.6 1.5e-06 28.2 2.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73207.1 - 1.2e-07 31.6 0.1 8.3e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS73207.1 - 2.1e-06 27.1 0.1 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_GDSL_2 PF13472.1 ETS73208.1 - 1.1e-07 32.1 0.0 1.7e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS73208.1 - 1.7e-07 31.2 0.0 4.1e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1510 PF07423.6 ETS73208.1 - 0.024 14.0 0.1 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1628 PF07790.6 ETS73208.1 - 0.076 13.7 0.5 0.21 12.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) ABC2_membrane_2 PF12679.2 ETS73208.1 - 0.083 11.7 0.7 0.14 10.9 0.1 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein SSP160 PF06933.6 ETS73208.1 - 0.94 7.3 11.6 1.3 6.9 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 ETS73210.1 - 4.3e-35 121.0 27.8 5.8e-35 120.6 19.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 ETS73210.1 - 0.014 15.7 0.0 0.058 13.7 0.0 2.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M35 PF02102.10 ETS73211.1 - 2.6e-90 302.7 16.4 2.9e-90 302.5 11.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 ETS73211.1 - 3.4e-09 37.3 0.4 6.1e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Abhydrolase_6 PF12697.2 ETS73213.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 ETS73214.1 - 3.8e-72 242.6 0.8 3.8e-72 242.6 0.5 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 ETS73214.1 - 5.3e-07 29.1 9.3 1.3e-06 27.9 6.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.17 ETS73214.1 - 0.057 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Senescence_reg PF04520.8 ETS73214.1 - 0.06 13.8 0.6 0.09 13.2 0.4 1.2 1 0 0 1 1 1 0 Senescence regulator adh_short PF00106.20 ETS73215.1 - 1.2e-26 93.6 2.9 1.9e-26 92.9 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73215.1 - 4.9e-24 85.4 0.1 6.1e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73215.1 - 1.7e-16 60.4 0.9 2.2e-16 60.0 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS73215.1 - 6.6e-08 32.2 0.1 1.3e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS73215.1 - 9.5e-05 21.2 0.0 0.00012 20.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 ETS73215.1 - 0.0077 16.6 1.5 1.4 9.4 0.1 2.7 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 ETS73215.1 - 0.014 14.2 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 ETS73215.1 - 0.019 13.9 0.1 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CTP_transf_2 PF01467.21 ETS73216.1 - 1.8e-05 24.8 0.2 7.5e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase WD40 PF00400.27 ETS73217.1 - 7.1e-22 76.4 9.8 6.3e-09 35.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 ETS73218.1 - 8.8e-26 89.9 0.1 1.6e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73218.1 - 6.9e-14 52.8 0.0 1.4e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS73218.1 - 4.8e-07 29.5 0.0 2.9e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Spt5-NGN PF03439.8 ETS73219.1 - 6e-24 83.5 0.0 1.1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 ETS73219.1 - 9.3e-22 77.7 63.6 2.8e-13 50.3 10.5 5.1 2 1 3 5 5 5 4 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 ETS73219.1 - 7.8e-16 58.4 9.5 7.8e-16 58.4 6.6 4.0 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 ETS73219.1 - 2.7e-07 30.0 15.4 0.0021 17.7 0.7 5.4 6 0 0 6 6 6 2 KOW motif YajC PF02699.10 ETS73219.1 - 4.1 7.1 10.2 12 5.6 0.1 4.0 4 1 1 5 5 5 0 Preprotein translocase subunit Glyco_hydro_61 PF03443.9 ETS73220.1 - 2.6e-56 190.8 0.1 3e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1966 PF09260.6 ETS73220.1 - 0.11 12.5 0.9 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) NQR2_RnfD_RnfE PF03116.10 ETS73222.1 - 0.01 15.0 2.4 0.015 14.5 1.7 1.2 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Pkinase PF00069.20 ETS73224.1 - 1.3e-44 152.2 0.0 3.8e-44 150.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS73224.1 - 8.9e-32 110.1 0.0 1.4e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS73224.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.10 ETS73225.1 - 5.2e-135 450.7 0.0 6e-135 450.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Bac_rhodopsin PF01036.13 ETS73226.1 - 9.8e-59 198.3 9.7 1.3e-58 197.9 6.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CHRD PF07452.7 ETS73227.1 - 0.012 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 CHRD domain FYTT PF07078.6 ETS73230.1 - 7.7e-06 25.4 2.3 0.00066 19.0 0.4 2.1 2 0 0 2 2 2 2 Forty-two-three protein Prog_receptor PF02161.10 ETS73230.1 - 0.038 12.8 2.4 0.044 12.6 1.7 1.1 1 0 0 1 1 1 0 Progesterone receptor RNA_pol_3_Rpc31 PF11705.3 ETS73230.1 - 0.13 12.1 10.2 0.22 11.4 7.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 ETS73230.1 - 0.16 11.4 6.8 0.24 10.8 4.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 ETS73230.1 - 0.18 9.4 2.3 0.17 9.5 1.6 1.1 1 0 0 1 1 1 0 Ycf1 Atrophin-1 PF03154.10 ETS73230.1 - 0.29 9.2 10.5 0.35 8.9 7.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family RRN3 PF05327.6 ETS73230.1 - 1.1 7.2 6.3 1.6 6.7 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GAGA_bind PF06217.7 ETS73230.1 - 1.1 9.1 5.4 1.5 8.7 3.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FAM178 PF14816.1 ETS73230.1 - 1.3 7.6 5.0 1.6 7.3 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 FoP_duplication PF13865.1 ETS73230.1 - 2.6 8.5 9.1 4.2 7.8 4.2 2.3 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Na_H_antiport_2 PF13726.1 ETS73234.1 - 0.014 15.3 2.4 0.062 13.2 1.7 2.0 1 1 0 1 1 1 0 Na+-H+ antiporter family NADH_Oxid_Nqo15 PF11497.3 ETS73235.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 CDC45 PF02724.9 ETS73236.1 - 5.2 4.9 14.2 10 4.0 9.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 ETS73236.1 - 6.4 4.3 7.6 9 3.9 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FoP_duplication PF13865.1 ETS73238.1 - 4.7 7.7 19.0 55 4.3 9.1 3.6 2 2 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.14 ETS73240.1 - 0.16 12.4 7.3 1.7 9.1 0.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Reo_sigmaC PF04582.7 ETS73242.1 - 0.0011 18.2 52.2 0.068 12.3 4.8 6.6 1 1 6 7 7 7 7 Reovirus sigma C capsid protein DUF3552 PF12072.3 ETS73242.1 - 0.0027 16.9 13.3 0.0027 16.9 9.2 8.3 2 2 7 9 9 9 4 Domain of unknown function (DUF3552) Spc7 PF08317.6 ETS73242.1 - 0.054 12.1 104.0 0.018 13.7 2.9 6.9 1 1 5 7 7 7 0 Spc7 kinetochore protein ATP-synt_E_2 PF08112.6 ETS73242.1 - 0.098 12.7 18.0 1.7 8.7 0.5 5.1 4 0 0 4 4 4 0 ATP synthase epsilon subunit AAA_13 PF13166.1 ETS73242.1 - 0.93 7.8 95.5 0.0074 14.8 5.7 4.7 1 1 2 4 4 4 0 AAA domain AAA_13 PF13166.1 ETS73244.1 - 0.72 8.2 43.9 0.099 11.0 11.4 2.1 1 1 1 2 2 2 0 AAA domain Kinesin-relat_1 PF12711.2 ETS73245.1 - 0.017 15.5 0.8 0.037 14.4 0.6 1.6 1 0 0 1 1 1 0 Kinesin motor T5orf172 PF10544.4 ETS73245.1 - 0.073 13.4 0.3 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 T5orf172 domain Lactamase_B_2 PF12706.2 ETS73246.1 - 2.6e-11 43.4 0.0 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS73246.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 ETS73247.1 - 0.0016 18.4 0.1 0.0042 17.0 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase DUF4196 PF13846.1 ETS73247.1 - 0.028 14.7 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) PI-PLC-X PF00388.14 ETS73248.1 - 4.8e-62 207.6 0.0 7.9e-62 206.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS73248.1 - 9.6e-38 128.7 0.0 2e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 ETS73248.1 - 4.2e-05 23.4 0.0 0.0024 17.8 0.0 2.6 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 ETS73248.1 - 0.0048 16.7 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 C2 domain peroxidase PF00141.18 ETS73249.1 - 1.1e-32 113.3 0.8 1.5e-32 112.9 0.6 1.1 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.2 ETS73249.1 - 0.25 11.1 1.3 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 F-box-like Fungal_trans PF04082.13 ETS73250.1 - 4.3e-20 71.6 0.0 1.1e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73250.1 - 1.5e-09 37.5 11.0 2.4e-09 36.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 ETS73251.1 - 1.4e-13 50.6 0.1 3.7e-13 49.2 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain CcmH PF03918.9 ETS73252.1 - 0.0037 16.2 0.2 0.45 9.4 0.0 2.4 2 0 0 2 2 2 2 Cytochrome C biogenesis protein Gpi16 PF04113.9 ETS73254.1 - 1.5e-236 785.8 0.0 2e-236 785.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 ETS73255.1 - 2.1e-72 243.7 0.1 2.6e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus AAA_13 PF13166.1 ETS73255.1 - 0.055 11.9 0.1 0.071 11.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 ETS73256.1 - 0.012 15.2 1.4 0.017 14.7 1.0 1.2 1 0 0 1 1 1 0 IncA protein CDC27 PF09507.5 ETS73256.1 - 0.58 9.3 27.7 1.1 8.4 19.2 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 ETS73256.1 - 1.3 8.8 19.9 1.7 8.4 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1479 PF07350.7 ETS73257.1 - 1.9e-155 517.4 0.0 2.3e-155 517.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) GMC_oxred_N PF00732.14 ETS73259.1 - 1.2e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS73259.1 - 1.2e-31 109.9 0.0 2.3e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS73259.1 - 5e-09 35.4 0.0 0.0004 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS73259.1 - 6.7e-06 25.2 0.0 0.00051 19.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS73259.1 - 2.2e-05 24.3 0.0 5.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS73259.1 - 0.00013 21.9 0.1 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS73259.1 - 0.0076 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS73259.1 - 0.019 14.0 0.1 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 ETS73259.1 - 0.026 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS73259.1 - 0.038 12.4 0.0 0.19 10.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Sugar_tr PF00083.19 ETS73260.1 - 3.4e-121 404.9 23.2 3.9e-121 404.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73260.1 - 7.8e-27 93.8 61.3 4e-24 85.0 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 ETS73261.1 - 6.8e-93 311.6 0.9 9.9e-93 311.0 0.6 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 ETS73261.1 - 1.3e-06 28.2 1.6 1.6e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 ETS73261.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Tyrosinase PF00264.15 ETS73262.1 - 4.7e-34 118.4 7.5 6.8e-34 117.9 5.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF885 PF05960.6 ETS73264.1 - 1.5e-47 162.9 0.1 3e-47 162.0 0.1 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Asparaginase_2 PF01112.13 ETS73265.1 - 2.4e-40 138.2 0.2 1.6e-19 69.7 0.0 3.6 3 1 0 3 3 3 3 Asparaginase Tim17 PF02466.14 ETS73266.1 - 6e-34 116.8 5.9 7.3e-34 116.5 4.1 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 ETS73267.1 - 2.9e-109 365.6 24.5 3.7e-109 365.2 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73267.1 - 1.8e-21 76.2 67.7 1.1e-17 63.7 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS73267.1 - 9.1e-08 30.7 7.8 5.2e-06 24.9 1.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_M20 PF01546.23 ETS73268.1 - 6e-23 81.3 0.0 1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 ETS73268.1 - 4.3e-18 64.4 0.5 0.00046 19.9 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 ETS73268.1 - 2e-06 27.4 0.0 3.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS73268.1 - 0.014 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PQQ_3 PF13570.1 ETS73268.1 - 3.2 8.1 5.4 3 8.2 0.0 3.6 5 0 0 5 5 5 0 PQQ-like domain DPBB_1 PF03330.13 ETS73272.1 - 4.3e-12 45.8 0.5 1.7e-11 43.9 0.1 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 ETS73272.1 - 2.9e-05 24.0 1.5 8.1e-05 22.6 0.2 2.2 2 0 0 2 2 2 1 Cerato-platanin Barwin PF00967.12 ETS73272.1 - 0.00055 19.6 1.4 0.0016 18.0 0.2 2.0 2 0 0 2 2 2 1 Barwin family Mo-co_dimer PF03404.11 ETS73272.1 - 0.006 16.2 0.1 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pollen_allerg_1 PF01357.16 ETS73272.1 - 0.0068 16.1 1.2 0.013 15.2 0.9 1.4 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.15 ETS73272.1 - 0.095 12.5 0.9 0.095 12.5 0.6 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Clr5 PF14420.1 ETS73273.1 - 1e-21 76.5 2.0 2.6e-21 75.2 1.4 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_19 PF14559.1 ETS73273.1 - 0.00083 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS73273.1 - 0.033 14.8 0.0 0.093 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ATG27 PF09451.5 ETS73274.1 - 2.8e-71 239.9 0.0 4e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Spt20 PF12090.3 ETS73275.1 - 9.1e-47 158.7 0.0 9.1e-47 158.7 0.0 5.5 3 2 0 3 3 3 1 Spt20 family Hexapep PF00132.19 ETS73277.1 - 6.7e-09 34.8 0.3 0.0003 20.1 0.0 2.5 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 ETS73277.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 ETS73277.1 - 0.039 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.1 ETS73277.1 - 0.11 12.1 6.7 30 4.2 4.5 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2 PF00096.21 ETS73278.1 - 0.00053 20.1 12.8 0.16 12.3 3.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS73278.1 - 0.005 17.0 12.2 0.09 13.1 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 ETS73278.1 - 0.0096 15.5 0.6 0.024 14.2 0.4 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 ETS73278.1 - 0.023 14.8 4.7 0.043 13.9 3.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 ETS73278.1 - 0.037 13.9 0.7 0.11 12.4 0.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS73278.1 - 1.8 8.9 11.4 0.31 11.4 3.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_S24e PF01282.14 ETS73279.1 - 5.5e-32 109.4 0.0 9.3e-32 108.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e LRR_1 PF00560.28 ETS73280.1 - 0.00011 21.7 2.2 1.9 8.8 0.1 5.3 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 ETS73280.1 - 0.00017 21.2 1.9 10 6.8 0.0 5.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 ETS73280.1 - 0.0031 17.4 2.6 4.2 7.7 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 ETS73280.1 - 0.005 16.4 1.3 13 5.5 0.0 4.5 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) adh_short_C2 PF13561.1 ETS73281.1 - 6.9e-31 107.8 0.5 8.2e-31 107.6 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS73281.1 - 2e-25 89.6 1.0 2.7e-25 89.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73281.1 - 3.2e-09 36.7 0.5 8.4e-09 35.3 0.3 1.6 1 1 0 1 1 1 1 KR domain Dioxygenase_C PF00775.16 ETS73282.1 - 8.7e-12 44.6 0.1 1.7e-11 43.7 0.1 1.5 1 1 0 1 1 1 1 Dioxygenase Pec_lyase_C PF00544.14 ETS73283.1 - 2.6e-29 102.1 3.9 1.7e-27 96.2 2.7 2.6 1 1 0 1 1 1 1 Pectate lyase Mito_carr PF00153.22 ETS73284.1 - 1.2e-45 153.0 8.6 1.5e-16 59.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 ETS73284.1 - 0.093 12.2 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif NAD_binding_10 PF13460.1 ETS73285.1 - 2.9e-10 40.4 0.0 3.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS73285.1 - 5.9e-08 32.4 0.0 7.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS73285.1 - 1.4e-06 27.3 0.0 0.017 14.0 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 ETS73285.1 - 4.8e-05 22.2 0.0 6.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETS73285.1 - 0.00012 22.0 0.1 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 ETS73285.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 ETS73285.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETS73285.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS73285.1 - 0.063 12.1 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 ETS73285.1 - 0.067 12.1 0.1 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 ETS73286.1 - 5.4e-17 62.4 0.1 9.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold BCA_ABC_TP_C PF12399.3 ETS73286.1 - 0.031 13.9 0.1 0.084 12.5 0.1 1.8 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Zn_clus PF00172.13 ETS73287.1 - 3.6e-05 23.5 7.3 7.2e-05 22.6 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73287.1 - 0.058 12.2 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Dickkopf_N PF04706.7 ETS73287.1 - 0.97 9.6 8.9 2.2 8.5 6.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.17 ETS73288.1 - 1.4e-73 248.0 0.0 1.9e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 ETS73288.1 - 4e-34 117.9 0.0 6.6e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETS73288.1 - 2.1e-23 82.8 0.2 5.3e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 ETS73288.1 - 4.5e-14 52.9 0.0 1.3e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 ETS73288.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 ETS73288.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain FAD_binding_6 PF00970.19 ETS73288.1 - 0.12 12.4 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS73288.1 - 0.17 11.7 0.0 3.5 7.5 0.0 2.6 2 1 1 3 3 3 0 Ferric reductase NAD binding domain adh_short_C2 PF13561.1 ETS73289.1 - 3e-27 95.9 0.0 3.7e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS73289.1 - 1.1e-21 77.4 1.9 1.5e-21 77.0 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73289.1 - 0.0003 20.4 0.9 0.00046 19.8 0.6 1.3 1 1 0 1 1 1 1 KR domain DLH PF01738.13 ETS73290.1 - 1.3e-21 76.8 0.0 1.5e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS73290.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 ETS73291.1 - 8.1e-33 113.5 28.2 1.1e-32 113.2 19.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 ETS73291.1 - 0.027 14.8 0.1 0.098 13.0 0.1 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2627 PF11118.3 ETS73291.1 - 0.37 10.9 0.1 0.37 10.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) Peptidase_M35 PF02102.10 ETS73292.1 - 2e-80 270.1 17.9 2.2e-80 270.0 12.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 ETS73292.1 - 4.8e-09 36.8 0.6 1e-08 35.8 0.3 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF4397 PF14344.1 ETS73292.1 - 0.00052 20.3 1.1 0.017 15.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4397) MmgE_PrpD PF03972.9 ETS73293.1 - 1.4e-70 237.7 1.7 1.7e-70 237.4 1.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ADH_zinc_N PF00107.21 ETS73294.1 - 4e-20 71.6 0.0 6.7e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73294.1 - 1.3e-05 26.1 0.0 2.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 ETS73296.1 - 9.4e-28 96.7 0.0 1.9e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73296.1 - 5.6e-09 35.7 8.5 1e-08 34.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS73297.1 - 8.2e-53 179.3 0.0 1.1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73297.1 - 9.6e-06 25.4 6.9 9.6e-06 25.4 4.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Conotoxin PF02950.12 ETS73298.1 - 0.012 16.4 0.4 0.012 16.4 0.3 4.2 5 0 0 5 5 5 0 Conotoxin Syndecan PF01034.15 ETS73298.1 - 0.059 13.0 0.4 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain NUDIX PF00293.23 ETS73299.1 - 3.5e-15 55.8 0.1 6.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 ETS73299.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 NUDIX domain MFS_1 PF07690.11 ETS73300.1 - 6.9e-21 74.3 35.9 6.7e-20 71.0 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS73300.1 - 2.2e-06 26.3 10.9 2.2e-06 26.3 7.6 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.19 ETS73300.1 - 3.7e-05 22.4 25.9 0.00052 18.7 18.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3938 PF13074.1 ETS73300.1 - 0.025 14.4 0.3 0.072 12.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF2811 PF10929.3 ETS73300.1 - 0.026 14.5 0.2 0.062 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) DUF4149 PF13664.1 ETS73300.1 - 2.2 8.4 8.9 0.2 11.7 0.9 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) Fil_haemagg_2 PF13332.1 ETS73301.1 - 0.069 12.9 3.7 0.075 12.8 2.6 1.2 1 0 0 1 1 1 0 Haemagluttinin repeat Zn_clus PF00172.13 ETS73302.1 - 7e-08 32.2 10.7 7e-08 32.2 7.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73302.1 - 7.8e-07 28.2 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PspA_IM30 PF04012.7 ETS73302.1 - 0.064 12.6 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.7 ETS73303.1 - 2.6 7.8 6.8 4.6 7.0 1.9 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Amidohydro_4 PF13147.1 ETS73304.1 - 1.6e-20 74.2 0.8 1.5e-14 54.6 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 ETS73304.1 - 1.7e-10 41.0 0.1 4.4e-08 33.1 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS73304.1 - 2.5e-10 40.0 0.2 8.6e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS73304.1 - 7.8e-07 28.6 6.0 4.4e-05 22.8 0.5 2.4 2 1 0 2 2 2 2 Amidohydrolase family TRCF PF03461.10 ETS73306.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 TRCF domain PGC7_Stella PF15549.1 ETS73306.1 - 0.05 13.6 2.4 0.51 10.3 0.3 2.2 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Pho88 PF10032.4 ETS73307.1 - 1e-82 276.0 0.2 1.2e-82 275.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 ETS73308.1 - 1.8e-29 101.0 2.2 3.7e-29 100.0 1.6 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 ETS73308.1 - 0.016 14.8 2.1 0.016 14.8 1.5 1.7 2 0 0 2 2 2 0 XPA protein N-terminal TF_Zn_Ribbon PF08271.7 ETS73308.1 - 0.97 8.8 7.1 5.5 6.4 0.7 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Pribosyltran_N PF13793.1 ETS73309.1 - 4.6e-43 145.6 0.9 3.3e-42 142.8 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 ETS73309.1 - 6.3e-42 143.3 1.7 3.1e-36 124.8 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 ETS73309.1 - 3.9e-13 49.2 1.0 1.3e-12 47.5 0.5 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS73309.1 - 0.0056 15.9 0.2 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.14 ETS73310.1 - 3.7e-61 204.3 0.3 7.5e-61 203.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.5 ETS73311.1 - 7e-36 122.6 0.0 8.5e-36 122.4 0.0 1.1 1 0 0 1 1 1 1 Ctf8 MFS_1 PF07690.11 ETS73312.1 - 5.2e-35 120.7 45.1 3.2e-33 114.9 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTH2 PF01981.11 ETS73314.1 - 5.7e-47 158.1 0.2 8.3e-47 157.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Baculo_PEP_C PF04513.7 ETS73315.1 - 4.5e-08 33.0 25.3 0.022 14.5 1.3 5.3 3 1 1 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETS73315.1 - 0.0027 16.9 3.7 0.0027 16.9 2.6 4.1 2 2 1 4 4 4 2 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 ETS73315.1 - 0.012 15.3 32.8 0.25 11.0 0.0 5.4 5 1 0 5 5 5 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 ETS73315.1 - 0.032 14.1 17.3 0.95 9.3 0.0 5.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) IncA PF04156.9 ETS73315.1 - 0.034 13.7 38.8 20 4.7 14.8 5.8 4 1 0 4 4 4 0 IncA protein Filament PF00038.16 ETS73315.1 - 0.053 12.9 37.2 0.032 13.7 15.7 3.9 3 1 0 3 3 3 0 Intermediate filament protein VASP_tetra PF08776.6 ETS73315.1 - 0.17 11.2 4.3 0.6 9.4 0.0 3.8 4 0 0 4 4 4 0 VASP tetramerisation domain HisKA_3 PF07730.8 ETS73315.1 - 0.37 11.1 8.3 5.9 7.3 0.2 4.5 2 1 3 5 5 5 0 Histidine kinase ApoO PF09769.4 ETS73315.1 - 1.3 8.6 5.7 1.6 8.4 0.6 3.3 2 1 2 4 4 4 0 Apolipoprotein O TIP49 PF06068.8 ETS73316.1 - 8.1e-174 577.9 4.2 9.6e-174 577.7 2.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 ETS73316.1 - 2.6e-08 34.1 0.4 3.3e-05 24.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS73316.1 - 6.1e-07 28.7 1.6 9.4e-05 21.5 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 ETS73316.1 - 2e-06 26.8 0.4 3.2e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 ETS73316.1 - 0.00057 20.0 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 ETS73316.1 - 0.00077 18.6 0.6 0.0077 15.4 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETS73316.1 - 0.001 19.0 0.0 0.0056 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ETS73316.1 - 0.0032 17.3 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS73316.1 - 0.022 14.5 0.1 0.074 12.8 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 ETS73316.1 - 0.031 13.6 0.1 0.07 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS73316.1 - 0.037 13.4 0.0 7 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 ETS73316.1 - 0.045 13.4 0.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 ETS73316.1 - 0.08 13.2 0.0 0.6 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS73316.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gp_dh_C PF02800.15 ETS73317.1 - 2.3e-74 248.0 0.2 3.3e-74 247.5 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 ETS73317.1 - 3.4e-60 202.3 0.1 5.7e-60 201.6 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS73317.1 - 0.0028 17.5 0.5 0.018 14.9 0.0 2.4 2 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 ETS73317.1 - 0.077 12.5 0.2 0.31 10.5 0.0 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS73317.1 - 0.083 12.0 0.1 0.52 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 ETS73318.1 - 2.2e-20 72.6 0.0 4e-20 71.8 0.0 1.4 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 ETS73318.1 - 6.3e-07 29.5 0.0 2e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS73318.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFA PF04828.9 ETS73319.1 - 1.9e-16 59.7 10.9 3.4e-09 36.5 0.5 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme AP_endonuc_2 PF01261.19 ETS73320.1 - 5.4e-32 110.8 0.2 8.9e-32 110.0 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DHquinase_I PF01487.10 ETS73321.1 - 1.2e-29 103.6 0.0 2.2e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 ETS73321.1 - 2.5e-19 69.1 0.0 1.1e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 ETS73321.1 - 4.1e-17 62.5 0.1 9e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 ETS73321.1 - 3.1e-12 46.7 0.0 9.6e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 ETS73321.1 - 0.00095 19.9 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ThiF PF00899.16 ETS73321.1 - 0.15 11.9 0.7 7.1 6.4 0.1 2.4 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 ETS73322.1 - 6.8e-15 54.6 0.9 1.5e-14 53.4 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73322.1 - 8.8e-09 35.1 11.3 1.7e-08 34.1 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asn_synthase PF00733.16 ETS73322.1 - 0.044 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase Shikimate_dh_N PF08501.6 ETS73323.1 - 3.3e-20 71.9 0.0 7e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS73323.1 - 6.5e-14 52.1 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 ETS73323.1 - 0.024 15.1 0.0 0.067 13.7 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 ETS73323.1 - 0.051 12.5 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase eRF1_3 PF03465.10 ETS73323.1 - 0.053 13.7 0.0 0.083 13.1 0.0 1.4 1 1 0 1 1 1 0 eRF1 domain 3 F420_oxidored PF03807.12 ETS73323.1 - 0.069 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 ETS73323.1 - 0.11 12.9 0.0 0.3 11.6 0.0 1.6 2 0 0 2 2 2 0 CoA binding domain ThiF PF00899.16 ETS73323.1 - 0.16 11.7 0.3 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 ThiF family Dioxygenase_C PF00775.16 ETS73324.1 - 1.2e-46 158.3 0.0 1.6e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS73324.1 - 6.7e-15 54.8 0.0 1.5e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fe-ADH PF00465.14 ETS73325.1 - 8.5e-70 235.2 0.1 9.7e-70 235.0 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS73325.1 - 2.7e-12 46.5 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase GrpB PF04229.9 ETS73326.1 - 2.6e-45 154.1 0.2 3.2e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 GrpB protein Shikimate_dh_N PF08501.6 ETS73327.1 - 3.2e-18 65.5 0.0 1.3e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS73327.1 - 4.2e-12 46.3 0.0 9.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 ETS73327.1 - 0.0095 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family SnoaL_4 PF13577.1 ETS73328.1 - 7.8e-08 32.2 0.1 1.2e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS73328.1 - 0.0067 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 ETS73328.1 - 0.008 16.2 0.7 0.012 15.6 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 ETS73328.1 - 0.014 15.7 0.5 0.024 15.0 0.4 1.3 1 0 0 1 1 1 0 SnoaL-like domain FAD_binding_4 PF01565.18 ETS73329.1 - 3.4e-24 84.8 0.8 6.1e-24 84.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain WSC PF01822.14 ETS73330.1 - 2.5e-13 49.7 8.9 2.5e-13 49.7 6.1 3.9 2 1 0 2 2 2 1 WSC domain Utp14 PF04615.8 ETS73330.1 - 4.6 5.2 11.8 5.7 4.9 8.2 1.1 1 0 0 1 1 1 0 Utp14 protein p450 PF00067.17 ETS73331.1 - 9.1e-68 228.8 0.0 1.2e-67 228.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 ETS73331.1 - 2.6e-65 220.4 0.0 3.7e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS73331.1 - 6.5e-15 55.8 0.1 3.9e-14 53.3 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 ETS73332.1 - 1.1e-22 79.9 0.1 1.6e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73332.1 - 3.1e-09 37.8 0.0 6.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS73332.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RTA1 PF04479.8 ETS73333.1 - 2.3e-51 174.4 12.4 3.6e-51 173.8 8.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Tannase PF07519.6 ETS73334.1 - 2.4e-88 296.9 0.8 8.8e-88 295.0 0.5 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 ETS73334.1 - 7.8e-05 21.9 0.2 0.011 14.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS73334.1 - 0.015 15.2 0.1 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73334.1 - 0.024 14.1 0.1 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tannase PF07519.6 ETS73335.1 - 2.4e-90 303.5 0.1 2.8e-90 303.3 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS73335.1 - 1.9e-07 31.2 0.0 1.2e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73335.1 - 2.2e-05 24.2 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS73335.1 - 0.00018 20.8 0.0 0.075 12.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS73335.1 - 0.00049 19.7 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 ETS73336.1 - 1.3e-67 228.3 0.0 1.6e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MMS19_C PF12460.3 ETS73336.1 - 0.029 13.0 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Cu_bind_like PF02298.12 ETS73337.1 - 0.006 16.3 0.1 0.02 14.7 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Bmp PF02608.9 ETS73337.1 - 0.044 12.5 0.1 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Basic membrane protein COesterase PF00135.23 ETS73338.1 - 7.5e-17 61.2 0.3 1.5e-16 60.2 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS73338.1 - 0.0005 19.7 0.0 0.0019 17.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Tannase PF07519.6 ETS73339.1 - 2.4e-126 422.2 5.7 2.9e-126 421.9 3.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Alpha-L-AF_C PF06964.7 ETS73340.1 - 4.9e-32 111.1 0.1 1.3e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus DUF2220 PF09983.4 ETS73340.1 - 0.086 11.9 0.7 0.16 11.1 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Sugar_tr PF00083.19 ETS73341.1 - 1.2e-91 307.6 23.2 1.4e-91 307.3 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73341.1 - 5.2e-23 81.3 26.2 5.2e-23 81.3 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.4 ETS73342.1 - 0.1 12.0 8.5 0.19 11.1 5.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Melibiase PF02065.13 ETS73344.1 - 6.4e-145 482.7 0.0 8e-145 482.4 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 ETS73344.1 - 1.2e-05 24.3 0.1 1.8e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 SART-1 PF03343.8 ETS73345.1 - 8.4e-149 496.7 63.7 1e-148 496.4 44.1 1.1 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 ETS73346.1 - 2.5e-101 339.4 0.4 3.2e-101 339.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 ETS73346.1 - 2.8e-33 113.3 1.0 9.3e-33 111.7 0.7 2.0 1 0 0 1 1 1 1 Starch binding domain AAA_17 PF13207.1 ETS73347.1 - 2e-06 28.6 0.0 4.3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 ETS73347.1 - 0.00027 20.6 0.0 0.00058 19.5 0.0 1.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 ETS73347.1 - 0.00029 20.4 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 ETS73347.1 - 0.0039 17.4 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS73347.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETS73347.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 ETS73347.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 ETS73347.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.9 ETS73348.1 - 1.1e-77 260.9 0.0 1.2e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS73348.1 - 6e-07 29.4 0.0 8.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ATP-grasp_2 PF08442.5 ETS73350.1 - 2.3e-78 262.2 1.4 2.3e-78 262.2 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 ETS73350.1 - 8.8e-27 93.5 0.4 1.6e-26 92.7 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 ETS73350.1 - 2.4e-07 30.2 0.1 7.2e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 ETS73350.1 - 0.00024 20.7 1.2 0.0034 16.9 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 ETS73350.1 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 ETS73350.1 - 0.013 15.1 0.2 1.8 8.1 0.0 2.4 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Peripla_BP_2 PF01497.13 ETS73350.1 - 0.036 13.1 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Zn_clus PF00172.13 ETS73351.1 - 2.4e-05 24.1 9.4 2.4e-05 24.1 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_mat-A PF03863.8 ETS73351.1 - 0.0051 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Phage maturation protein DUF3112 PF11309.3 ETS73352.1 - 5.6e-38 130.2 10.9 9.1e-38 129.5 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) HXXEE PF13787.1 ETS73353.1 - 9.1e-25 87.2 4.1 5.3e-14 52.5 0.2 4.2 2 2 2 4 4 4 2 Protein of unknown function with HXXEE motif NmrA PF05368.8 ETS73354.1 - 1.2e-36 126.0 0.0 1.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS73354.1 - 9.4e-13 48.5 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS73354.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS73354.1 - 0.0002 20.1 0.0 0.00031 19.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETS73354.1 - 0.00062 19.4 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS73354.1 - 0.0023 17.4 0.0 0.0052 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS73354.1 - 0.0024 16.8 0.0 0.0072 15.2 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 ETS73354.1 - 0.01 16.1 0.2 1.3 9.3 0.0 2.4 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 ETS73355.1 - 5.6e-18 64.7 4.6 7.9e-18 64.2 2.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2802 PF10975.3 ETS73355.1 - 0.36 10.5 2.2 9.1 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Aldolase_II PF00596.16 ETS73356.1 - 3.3e-41 140.9 1.0 4.3e-41 140.5 0.7 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ecl1 PF12855.2 ETS73357.1 - 5.5e-08 31.9 1.9 8.7e-08 31.3 1.3 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Tis11B_N PF04553.7 ETS73357.1 - 0.0078 16.3 1.0 0.012 15.8 0.7 1.4 1 0 0 1 1 1 1 Tis11B like protein, N terminus Med12-PQL PF12144.3 ETS73357.1 - 0.017 14.4 0.7 0.023 14.0 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain zf-MYND PF01753.13 ETS73357.1 - 0.42 10.5 3.1 0.83 9.5 2.1 1.4 1 0 0 1 1 1 0 MYND finger Cpn60_TCP1 PF00118.19 ETS73359.1 - 8.9e-163 542.3 0.8 1e-162 542.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 ETS73360.1 - 3e-42 143.4 12.1 3e-42 143.4 8.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) RNA_polI_A34 PF08208.6 ETS73360.1 - 0.035 13.7 7.6 0.05 13.2 5.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 LCD1 PF09798.4 ETS73360.1 - 0.38 8.6 4.2 0.47 8.3 2.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Peptidase_S49_N PF08496.5 ETS73360.1 - 1.3 8.7 5.9 2 8.2 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DNA_pol3_a_NII PF11490.3 ETS73360.1 - 2.4 7.8 10.9 3.7 7.1 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RNase_H2-Ydr279 PF09468.5 ETS73360.1 - 2.5 7.2 7.0 3.8 6.6 4.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4407 PF14362.1 ETS73360.1 - 4.5 6.1 6.8 4.9 6.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.11 ETS73360.1 - 4.6 6.6 11.8 6.7 6.1 8.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Med19 PF10278.4 ETS73360.1 - 9 5.9 11.4 15 5.1 7.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 His_Phos_1 PF00300.17 ETS73361.1 - 9.6e-34 116.7 1.1 2e-33 115.7 0.1 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 ETS73361.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2456 PF10445.4 ETS73362.1 - 0.011 15.5 1.1 0.49 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) Zn_clus PF00172.13 ETS73363.1 - 0.00022 21.0 7.2 0.00042 20.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73363.1 - 0.001 18.0 0.3 0.0035 16.2 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS73364.1 - 1.6e-28 99.4 65.4 2.4e-25 89.0 33.1 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73364.1 - 1.4e-09 37.0 15.9 1.4e-09 37.0 11.0 2.8 1 1 0 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 ETS73365.1 - 1.4e-71 240.5 0.0 1.6e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 ETS73366.1 - 3.9e-23 82.1 0.1 5.9e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73366.1 - 3.4e-11 43.1 0.0 4.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73366.1 - 3.1e-05 23.8 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73366.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ETS73366.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PP-binding PF00550.20 ETS73367.1 - 0.00014 22.0 0.1 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 ETS73368.1 - 6.2e-21 74.8 0.0 8.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS73368.1 - 2e-16 60.3 0.0 2.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73368.1 - 3.6e-10 40.8 0.0 6.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS73368.1 - 3.8e-08 32.9 0.0 2.4e-07 30.3 0.0 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.20 ETS73369.1 - 5.4e-16 58.9 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73369.1 - 6.3e-10 39.0 0.0 8.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73369.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73369.1 - 0.00054 19.4 0.0 0.00088 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73369.1 - 0.0025 17.8 0.1 0.0045 17.0 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding DUF3328 PF11807.3 ETS73371.1 - 8.9e-16 58.2 0.1 1.4e-15 57.6 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acyl_transf_3 PF01757.17 ETS73372.1 - 1.5e-18 66.7 29.6 3.8e-18 65.4 20.5 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 ETS73372.1 - 0.002 17.5 9.5 0.0038 16.6 2.3 3.0 3 1 0 3 3 3 2 Protein of unknown function (DUF1624) Glyco_trans_2_3 PF13632.1 ETS73373.1 - 2.8e-12 46.7 5.2 2.8e-12 46.7 3.6 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS73373.1 - 1.3e-11 44.8 0.4 2.6e-11 43.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS73373.1 - 7.7e-10 38.3 0.5 4.2e-09 35.9 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 ETS73373.1 - 8.4e-09 34.3 0.7 1e-07 30.7 0.5 2.1 1 1 0 1 1 1 1 Chitin synthase DUF3353 PF11833.3 ETS73373.1 - 0.056 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Glycos_transf_2 PF00535.21 ETS73373.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 YqjK PF13997.1 ETS73373.1 - 7.3 6.8 9.8 0.19 11.8 0.9 2.7 2 1 1 3 3 3 0 YqjK-like protein EBV-NA1 PF02905.9 ETS73374.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Alpha-L-AF_C PF06964.7 ETS73375.1 - 5.1e-37 127.3 0.4 7.5e-37 126.8 0.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus p450 PF00067.17 ETS73376.1 - 1.6e-57 195.0 0.0 2.2e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 ETS73378.1 - 1.3e-05 24.0 0.3 2.1e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.15 ETS73379.1 - 3.2e-47 161.5 1.6 4.3e-47 161.1 1.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase E1-E2_ATPase PF00122.15 ETS73380.1 - 0.18 10.8 0.3 0.32 9.9 0.2 1.5 1 0 0 1 1 1 0 E1-E2 ATPase p450 PF00067.17 ETS73381.1 - 2.7e-48 164.6 0.0 3.8e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.9 ETS73383.1 - 8.2e-20 70.5 0.1 1.2e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S8 PF00082.17 ETS73385.1 - 1.9e-17 63.3 0.4 4.3e-17 62.1 0.2 1.5 1 1 0 1 1 1 1 Subtilase family Ank_3 PF13606.1 ETS73385.1 - 0.00018 21.3 0.2 0.41 11.0 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 ETS73385.1 - 0.0049 17.1 0.2 0.35 11.2 0.1 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS73385.1 - 0.064 13.7 0.0 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 ETS73385.1 - 0.07 12.9 0.1 0.77 9.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat DUF2435 PF10363.4 ETS73385.1 - 0.1 12.4 0.0 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Ank_2 PF12796.2 ETS73386.1 - 8.9e-118 384.9 11.7 1.4e-19 70.1 0.5 13.2 5 5 9 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 ETS73386.1 - 9e-99 318.7 37.4 1e-07 31.3 0.1 24.4 24 1 0 24 24 24 18 Ankyrin repeat Ank_4 PF13637.1 ETS73386.1 - 1.1e-84 277.4 24.4 8.4e-07 29.3 0.0 17.8 10 5 8 18 18 18 17 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS73386.1 - 3.7e-83 271.6 30.3 2.2e-10 40.4 0.2 17.8 11 6 9 20 20 20 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73386.1 - 5.7e-77 245.9 20.0 9.3e-05 22.3 0.2 23.3 23 0 0 23 23 23 16 Ankyrin repeat ZZ PF00569.12 ETS73386.1 - 3.7e-05 23.1 5.8 8.6e-05 22.0 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type ABM PF03992.11 ETS73387.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Pectate_lyase_3 PF12708.2 ETS73390.1 - 8.6e-58 196.1 21.2 9.5e-51 173.0 3.7 3.9 4 1 1 5 5 5 2 Pectate lyase superfamily protein Acetyltransf_4 PF13420.1 ETS73391.1 - 2.8e-09 37.1 0.0 3.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS73391.1 - 3.8e-09 36.4 0.0 5.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS73391.1 - 9.9e-09 35.2 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS73391.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS73391.1 - 0.004 17.0 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Na_Ca_ex PF01699.19 ETS73392.1 - 1.4e-16 60.3 4.2 1.8e-16 59.9 2.9 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein ABC2_membrane_5 PF13346.1 ETS73392.1 - 0.036 13.3 1.7 0.062 12.5 1.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Yip1 PF04893.12 ETS73392.1 - 0.42 10.1 8.2 0.6 9.5 5.7 1.3 1 1 0 1 1 1 0 Yip1 domain FtsX PF02687.16 ETS73392.1 - 0.59 9.9 6.4 0.19 11.4 2.2 1.8 2 1 0 2 2 2 0 FtsX-like permease family VCBS PF13517.1 ETS73393.1 - 1.4e-28 98.9 76.2 1.8e-09 37.8 4.3 8.3 4 3 5 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS73393.1 - 3.7e-16 58.2 49.6 0.00036 20.1 1.9 8.5 7 0 0 7 7 7 6 FG-GAP repeat Lipase_GDSL PF00657.17 ETS73393.1 - 4e-12 46.4 0.1 8.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS73393.1 - 8.3e-10 39.0 0.1 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 ETS73393.1 - 3.4e-07 29.8 16.5 0.089 12.2 0.0 6.1 3 2 3 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 ETS73393.1 - 3.4e-05 23.6 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans_2 PF11951.3 ETS73394.1 - 2.6e-10 39.4 0.0 3.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73394.1 - 0.0012 18.7 1.1 0.0023 17.7 0.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.1 ETS73396.1 - 9.8e-05 22.7 0.0 0.68 10.5 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS73396.1 - 0.0006 20.1 0.0 0.0061 16.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS73396.1 - 0.0077 16.3 0.0 5.5 7.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 ETS73397.1 - 1.2e-20 73.4 0.1 1.5e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS73398.1 - 1.2e-53 182.2 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS73399.1 - 4.3e-19 68.3 0.0 3.4e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MCPsignal PF00015.16 ETS73400.1 - 1 8.8 7.1 2.3 7.6 4.9 1.6 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.6 ETS73400.1 - 1.6 8.4 4.4 2.5 7.8 3.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 ETS73400.1 - 2.7 7.2 5.8 6.7 5.9 4.0 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Ank_2 PF12796.2 ETS73401.1 - 2.3e-14 53.4 0.0 0.00021 21.5 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS73401.1 - 4.1e-11 42.7 3.7 0.61 10.4 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73401.1 - 4.9e-10 38.6 6.5 0.98 9.8 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 ETS73401.1 - 7.6e-07 29.4 0.1 5.5 7.6 0.0 5.7 4 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS73401.1 - 5.6e-05 22.7 16.2 2.2 8.2 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Pkinase PF00069.20 ETS73402.1 - 7.3e-28 97.4 0.0 1.2e-27 96.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS73402.1 - 2.9e-13 49.4 0.0 3.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS73402.1 - 0.0059 15.5 0.1 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS73402.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TilS PF09179.6 ETS73403.1 - 0.051 13.5 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TilS substrate binding domain HATPase_c PF02518.21 ETS73405.1 - 1.5e-20 72.9 0.1 4.7e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS73405.1 - 5e-19 68.3 0.0 1.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 ETS73405.1 - 4.3e-12 45.8 0.1 1.3e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Glyco_hydro_cc PF11790.3 ETS73406.1 - 1.4e-49 168.7 0.9 2.2e-49 168.0 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ecm33 PF12454.3 ETS73406.1 - 0.018 14.9 0.1 0.018 14.9 0.0 2.9 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Cellulase PF00150.13 ETS73406.1 - 0.043 13.0 0.2 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Cation_ATPase_C PF00689.16 ETS73408.1 - 0.23 10.9 9.0 0.5 9.8 6.3 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4191 PF13829.1 ETS73408.1 - 3.2 6.8 6.6 0.96 8.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4191) zf-RING_2 PF13639.1 ETS73409.1 - 4.8e-14 51.8 4.4 7.5e-14 51.2 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS73409.1 - 6.3e-08 32.6 0.1 1.2e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS73409.1 - 7.7e-07 28.6 2.7 1.2e-06 28.0 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS73409.1 - 1.4e-05 25.0 4.6 2.2e-05 24.3 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS73409.1 - 1.4e-05 24.7 1.7 2.2e-05 24.0 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS73409.1 - 0.00011 21.7 1.3 0.00018 21.0 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS73409.1 - 0.0015 18.3 0.7 0.0027 17.4 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETS73409.1 - 0.027 14.0 2.2 0.047 13.2 1.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 ETS73409.1 - 0.21 11.6 2.4 0.34 10.9 1.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 ETS73409.1 - 0.72 9.5 2.4 1.4 8.7 1.6 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 ETS73409.1 - 6.8 6.7 6.4 7.6 6.5 2.4 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain CAP_GLY PF01302.20 ETS73410.1 - 1.1e-22 79.5 1.5 1.5e-22 79.0 1.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 ETS73410.1 - 6.1e-21 74.4 0.0 9.2e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 ETS73410.1 - 6.4e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.26 ETS73411.1 - 6.9e-10 38.8 0.8 4.4e-09 36.2 0.5 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS73411.1 - 4.5e-08 33.0 0.3 3.2e-07 30.3 0.1 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 ETS73413.1 - 1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS73413.1 - 7.5e-08 32.2 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73413.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73413.1 - 9.3e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73413.1 - 9.7e-07 29.1 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73413.1 - 4.3e-06 26.4 0.0 5.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS73413.1 - 8.3e-06 25.8 0.9 2.3e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 ETS73414.1 - 2.4e-19 69.9 0.2 3.8e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SRX PF09201.5 ETS73414.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRX NAD_binding_3 PF03447.11 ETS73414.1 - 0.094 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 ETS73414.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aldo_ket_red PF00248.16 ETS73415.1 - 2.7e-23 82.1 0.0 4.8e-22 78.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family VHS PF00790.14 ETS73416.1 - 0.0016 18.1 0.0 0.0054 16.3 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-C2HC_2 PF13913.1 ETS73416.1 - 0.024 14.2 3.9 0.12 12.0 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 ETS73416.1 - 0.058 12.8 0.4 0.79 9.2 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 CTD_bind PF04818.8 ETS73416.1 - 0.072 13.3 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 ETS73416.1 - 0.12 12.4 0.9 0.36 11.0 0.6 1.8 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-C2H2 PF00096.21 ETS73416.1 - 0.27 11.6 2.3 20 5.7 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3487 PF11990.3 ETS73417.1 - 0.77 9.1 7.8 0.099 12.0 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Cu_bind_like PF02298.12 ETS73418.1 - 0.014 15.1 0.3 0.014 15.1 0.2 2.8 2 1 0 2 2 2 0 Plastocyanin-like domain ALAD PF00490.16 ETS73418.1 - 0.66 8.8 0.0 0.66 8.8 0.0 2.2 2 1 0 2 2 2 0 Delta-aminolevulinic acid dehydratase SMN PF06003.7 ETS73419.1 - 3e-06 26.5 9.1 0.00016 20.8 0.7 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.17 ETS73420.1 - 2.5e-17 62.2 0.0 7e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS73420.1 - 1.8e-11 43.8 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS73420.1 - 1.8e-09 37.3 0.1 4.1e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAB PF10375.4 ETS73421.1 - 2.3e-08 33.3 0.1 4.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 ETS73421.1 - 0.0046 16.4 56.2 0.013 14.9 20.3 2.2 1 1 1 2 2 2 2 Intermediate filament protein DUF3584 PF12128.3 ETS73421.1 - 0.021 12.1 58.3 0.077 10.3 25.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 ETS73421.1 - 0.25 11.6 23.0 0.063 13.5 0.7 5.0 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 ETS73421.1 - 1.1 8.6 25.4 0.095 12.0 0.3 3.9 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 ETS73421.1 - 1.1 9.1 66.1 3.8 7.3 13.2 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 ETS73421.1 - 1.3 7.3 60.1 3.9 5.8 7.6 3.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Tropomyosin PF00261.15 ETS73421.1 - 1.5 7.8 62.3 22 4.0 22.3 2.9 1 1 1 2 2 2 0 Tropomyosin Lectin_N PF03954.9 ETS73421.1 - 1.7 8.0 24.5 1.1 8.6 2.9 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Reo_sigmaC PF04582.7 ETS73421.1 - 3.4 6.7 15.8 1.4 8.0 0.3 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 ETS73421.1 - 4.2 6.9 57.0 0.72 9.4 10.7 4.1 1 1 4 5 5 5 0 Mnd1 family Baculo_PEP_C PF04513.7 ETS73421.1 - 5.2 6.8 18.4 0.97 9.2 1.7 3.7 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 ETS73421.1 - 6.3 6.0 52.8 7.8 5.7 15.8 3.7 1 1 1 2 2 1 0 Laminin Domain I RskA PF10099.4 ETS73422.1 - 4.2 7.0 8.0 26 4.4 4.5 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA CHD5 PF04420.9 ETS73423.1 - 1.2e-60 203.8 1.8 1.5e-60 203.5 1.2 1.1 1 0 0 1 1 1 1 CHD5-like protein Myosin_tail_1 PF01576.14 ETS73423.1 - 0.006 14.3 0.9 0.0076 14.0 0.6 1.0 1 0 0 1 1 1 1 Myosin tail DUF1515 PF07439.6 ETS73423.1 - 0.049 13.4 0.6 0.088 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) FlxA PF14282.1 ETS73423.1 - 0.068 13.1 0.8 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 FlxA-like protein TMEM247 PF15444.1 ETS73423.1 - 0.094 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1640 PF07798.6 ETS73423.1 - 0.47 10.4 3.5 0.095 12.7 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) PPTA PF01239.17 ETS73424.1 - 6.1e-11 41.1 9.6 0.00021 20.5 0.2 4.8 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat Cnd1 PF12717.2 ETS73424.1 - 0.016 15.0 0.1 0.045 13.6 0.0 1.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Asp PF00026.18 ETS73425.1 - 1e-68 231.9 8.6 1.7e-68 231.2 5.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS73425.1 - 1.1e-10 41.6 0.1 1.1e-10 41.6 0.1 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 ETS73425.1 - 0.0011 18.5 0.2 0.0033 16.9 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal BAAT_C PF08840.6 ETS73425.1 - 0.0057 16.3 0.7 3.7 7.2 0.5 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Asp_protease_2 PF13650.1 ETS73425.1 - 0.083 13.4 4.9 0.27 11.7 0.0 3.5 3 1 0 3 3 3 0 Aspartyl protease Na_H_Exchanger PF00999.16 ETS73426.1 - 1.7e-32 112.4 37.9 8.4e-26 90.3 17.2 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family MFS_1_like PF12832.2 ETS73426.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.7 4 0 0 4 4 4 0 MFS_1 like family SLAC1 PF03595.12 ETS73427.1 - 4.3e-73 245.8 45.4 4.9e-73 245.6 31.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PP2C PF00481.16 ETS73428.1 - 1.5e-34 119.5 0.0 4.2e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETS73428.1 - 0.00064 19.1 0.1 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C HET PF06985.6 ETS73429.1 - 1.1e-24 87.1 0.1 2.5e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MEKHLA PF08670.6 ETS73429.1 - 0.039 13.4 0.4 1.3 8.5 0.0 2.8 3 0 0 3 3 3 0 MEKHLA domain Peptidase_S41 PF03572.13 ETS73430.1 - 3.2e-08 33.1 0.0 1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 NACHT PF05729.7 ETS73431.1 - 1.4e-06 28.0 0.1 3.7e-06 26.6 0.0 1.7 2 0 0 2 2 1 1 NACHT domain NB-ARC PF00931.17 ETS73431.1 - 1.7e-06 27.1 0.0 2.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETS73431.1 - 8e-06 26.0 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS73431.1 - 0.00014 22.6 0.0 0.00057 20.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS73431.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETS73431.1 - 0.0012 18.8 0.1 0.0044 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS73431.1 - 0.0032 17.6 0.0 0.0078 16.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETS73431.1 - 0.0057 16.7 0.0 0.54 10.3 0.0 2.8 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 ETS73431.1 - 0.0061 16.5 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 ETS73431.1 - 0.0092 15.4 0.0 0.023 14.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS73431.1 - 0.0096 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS73431.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 ETS73431.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 ETS73431.1 - 0.04 13.6 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 ETS73431.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.7 ETS73431.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 ETS73431.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 ETS73431.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BC10 PF06726.7 ETS73432.1 - 1.7e-16 60.0 11.0 2.6e-16 59.3 7.6 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF2461 PF09365.5 ETS73435.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Glycos_transf_2 PF00535.21 ETS73436.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Bacteriocin_IIc PF10439.4 ETS73436.1 - 0.27 11.3 1.9 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Zn_clus PF00172.13 ETS73437.1 - 6.2e-05 22.8 15.2 0.00011 22.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF829 PF05705.9 ETS73438.1 - 2.4e-39 135.4 0.0 3e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Lumazine_bd_2 PF12893.2 ETS73439.1 - 2.8e-22 79.4 0.1 3.2e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.2 ETS73439.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain ADH_N PF08240.7 ETS73440.1 - 4.5e-21 74.6 0.0 8.6e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73440.1 - 3.4e-13 49.2 0.1 5.3e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS73440.1 - 0.11 11.5 0.2 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 ETS73441.1 - 1.3e-29 103.0 32.3 1.8e-29 102.6 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.23 ETS73442.1 - 9.2e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.11 ETS73442.1 - 9.7e-06 24.5 0.0 1.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Peptidase_C26 PF07722.8 ETS73442.1 - 0.0094 15.4 0.8 0.074 12.4 0.6 2.4 1 1 0 1 1 1 1 Peptidase C26 Zn_clus PF00172.13 ETS73443.1 - 2.5e-09 36.8 10.1 5.6e-09 35.7 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73443.1 - 5.1e-05 22.2 1.2 9.7e-05 21.3 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 ETS73444.1 - 1.3e-11 44.8 0.0 5.8e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 ETS73445.1 - 1.2e-16 61.0 1.5 5.1e-14 52.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS73445.1 - 2.2e-06 27.4 0.1 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73445.1 - 2.3e-06 27.5 0.1 1.5e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73445.1 - 0.001 18.5 0.1 0.0067 15.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73445.1 - 0.0011 19.0 0.1 0.026 14.5 0.1 2.6 1 1 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 ETS73447.1 - 3.3e-56 190.7 0.0 4.1e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS73448.1 - 1.7e-12 47.6 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73448.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73448.1 - 0.00026 20.8 0.0 0.00034 20.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73448.1 - 0.015 14.7 0.0 0.16 11.3 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 ETS73449.1 - 9.9e-20 70.4 0.7 2e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS73449.1 - 5.9e-10 38.8 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS73449.1 - 0.0033 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Abhydrolase_6 PF12697.2 ETS73450.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73450.1 - 2.8e-15 56.3 0.0 4.1e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS73450.1 - 1.9e-07 30.8 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS73450.1 - 4.8e-07 29.2 0.0 0.00059 19.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 ETS73450.1 - 9.4e-06 24.3 0.0 3.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 ETS73450.1 - 0.00043 19.8 0.2 0.025 14.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 ETS73450.1 - 0.0013 18.5 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 ETS73450.1 - 0.0055 15.3 0.0 0.015 13.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 ETS73450.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family ketoacyl-synt PF00109.21 ETS73451.1 - 4.6e-66 222.8 0.0 7.9e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 ETS73451.1 - 6.7e-57 192.8 0.0 1.1e-56 192.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 ETS73451.1 - 4.1e-51 173.2 0.0 8.1e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 ETS73451.1 - 1e-50 172.9 0.0 1.9e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS73451.1 - 8.5e-38 129.8 0.8 2e-37 128.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS73451.1 - 7.1e-35 119.4 0.8 1.4e-33 115.2 0.2 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS73451.1 - 9.3e-19 67.2 0.0 2.1e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73451.1 - 1.6e-13 51.6 0.0 4.3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS73451.1 - 4e-08 32.9 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS73451.1 - 7.4e-07 29.3 0.0 2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS73451.1 - 7.6e-05 21.8 0.1 0.00071 18.6 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Peptidase_M28 PF04389.12 ETS73452.1 - 3.5e-27 95.2 0.6 6.1e-27 94.4 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS73452.1 - 0.00031 20.3 0.1 0.00045 19.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Methyltransf_2 PF00891.13 ETS73453.1 - 1.7e-21 76.5 0.0 2.5e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_34 PF13601.1 ETS73453.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.2 ETS73453.1 - 0.035 13.7 1.7 0.077 12.6 0.1 2.3 3 0 0 3 3 3 0 MarR family HTH_IclR PF09339.5 ETS73453.1 - 0.05 13.1 1.6 0.13 11.9 0.2 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.15 ETS73453.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator FeoC PF09012.5 ETS73453.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_5 PF01022.15 ETS73453.1 - 0.18 11.4 1.3 0.34 10.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Dimerisation PF08100.6 ETS73453.1 - 0.51 10.2 3.2 0.6 9.9 0.6 2.3 2 0 0 2 2 2 0 Dimerisation domain Mac PF12464.3 ETS73455.1 - 6.8e-05 22.8 0.0 8.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Maltose acetyltransferase His_Phos_1 PF00300.17 ETS73455.1 - 0.03 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF2410 PF10307.4 ETS73456.1 - 9.3e-81 269.9 0.0 1.4e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) MFS_1 PF07690.11 ETS73457.1 - 1.1e-34 119.7 36.8 1.1e-34 119.7 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73457.1 - 1.4e-07 30.4 15.7 1.4e-07 30.4 10.9 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter AAA_16 PF13191.1 ETS73458.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 ETS73458.1 - 0.004 16.4 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FHA PF00498.21 ETS73459.1 - 2.5e-15 56.3 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 ETS73459.1 - 6.4 5.1 33.1 8.7 4.6 23.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DuffyBP_N PF12377.3 ETS73461.1 - 0.14 12.4 0.3 7.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Duffy binding protein N terminal MFS_1 PF07690.11 ETS73462.1 - 5.9e-31 107.4 53.0 9e-22 77.2 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS73462.1 - 5.3e-12 44.8 10.6 5.3e-12 44.8 7.3 2.3 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 ETS73462.1 - 0.00059 18.5 20.5 0.00059 18.5 14.2 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 ETS73462.1 - 0.00093 18.9 10.1 0.0017 18.1 1.0 2.9 2 0 0 2 2 2 2 MFS_1 like family OPT PF03169.10 ETS73463.1 - 4.4e-158 527.5 53.0 5.1e-158 527.3 36.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 ETS73463.1 - 0.42 9.7 4.4 0.15 11.1 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DNA_primase_S PF01896.14 ETS73464.1 - 5.9e-55 185.0 0.4 1.1e-54 184.2 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF3942 PF13078.1 ETS73464.1 - 0.08 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) Tyrosinase PF00264.15 ETS73465.1 - 8.1e-50 170.0 0.3 1.2e-49 169.5 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase CP2 PF04516.10 ETS73466.1 - 1.9e-84 282.4 0.0 2.9e-84 281.8 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 ETS73466.1 - 0.018 13.5 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Tektin family Not3 PF04065.10 ETS73466.1 - 0.028 13.6 0.8 0.049 12.9 0.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component SAP PF02037.22 ETS73467.1 - 1.5e-08 33.9 1.1 0.00046 19.6 0.1 2.8 2 0 0 2 2 2 2 SAP domain LMBR1 PF04791.11 ETS73467.1 - 0.33 9.4 0.3 0.42 9.1 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Oxysterol_BP PF01237.13 ETS73468.1 - 2.2e-54 184.3 0.0 5.4e-44 150.1 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein UDPGT PF00201.13 ETS73469.1 - 1.1e-07 30.7 0.0 3.2e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 ETS73469.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain XPG_I PF00867.13 ETS73470.1 - 2.7e-17 62.6 0.0 4.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ETS73470.1 - 7.4e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Epimerase PF01370.16 ETS73471.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS73471.1 - 2.6e-10 39.4 0.0 3.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS73471.1 - 5.3e-10 38.6 0.1 6.3e-09 35.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS73471.1 - 9.7e-10 38.7 0.5 3.6e-09 36.8 0.3 2.0 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 ETS73471.1 - 1.2e-06 28.3 0.8 8.7e-06 25.5 0.6 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 ETS73471.1 - 2e-05 23.9 0.3 5.8e-05 22.4 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 ETS73471.1 - 0.00023 21.1 0.6 0.0011 18.8 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS73471.1 - 0.0039 16.1 0.0 0.033 13.0 0.0 2.0 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_transf_36 PF06165.6 ETS73472.1 - 1.8e-20 72.8 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 ETS73472.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family Bac_rhamnosid PF05592.6 ETS73472.1 - 0.0014 16.9 0.2 0.003 15.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS73472.1 - 0.0015 17.3 0.3 0.0025 16.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 AT_hook PF02178.14 ETS73473.1 - 3.2 7.7 22.8 0.26 11.1 0.7 4.7 4 0 0 4 4 4 0 AT hook motif eIF2A PF08662.6 ETS73474.1 - 1.3e-80 269.7 0.2 6.1e-79 264.2 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 ETS73474.1 - 1.7e-06 27.6 0.2 1.8 8.5 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CDV3 PF15359.1 ETS73474.1 - 0.036 14.1 3.8 0.049 13.6 0.1 2.9 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Amino_oxidase PF01593.19 ETS73476.1 - 4.4e-11 42.5 0.3 1e-09 38.0 0.2 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS73476.1 - 6e-11 41.8 0.1 3.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS73476.1 - 1.5e-09 37.7 0.1 4.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS73476.1 - 1.9e-05 24.9 0.0 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS73476.1 - 0.017 14.0 0.0 0.059 12.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS73476.1 - 0.022 14.5 0.3 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS73476.1 - 0.055 13.3 0.0 5.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS73476.1 - 0.093 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS73476.1 - 0.14 12.1 0.1 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Helitron_like_N PF14214.1 ETS73479.1 - 3.4e-30 105.1 0.4 3.4e-30 105.1 0.3 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Rep_1 PF01446.12 ETS73479.1 - 0.0037 16.6 0.1 0.0069 15.7 0.1 1.3 1 0 0 1 1 1 1 Replication protein DUF2717 PF10911.3 ETS73480.1 - 0.06 12.8 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Drc1-Sld2 PF11719.3 ETS73481.1 - 6.9e-92 308.7 26.1 7.9e-92 308.5 18.1 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein SOG2 PF10428.4 ETS73481.1 - 0.55 8.8 4.2 1 7.9 2.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_2 PF13639.1 ETS73482.1 - 3.3e-06 26.8 11.0 5.7e-06 26.0 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS73482.1 - 5.7e-06 25.8 8.1 1e-05 25.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS73482.1 - 1.3e-05 25.1 8.3 2.3e-05 24.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS73482.1 - 6.1e-05 22.6 8.7 9.5e-05 21.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS73482.1 - 0.00017 21.6 9.3 0.00048 20.1 6.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger IGFBP PF00219.13 ETS73482.1 - 2.2 8.9 8.3 0.22 12.0 2.3 1.8 2 0 0 2 2 2 0 Insulin-like growth factor binding protein zf-MIZ PF02891.15 ETS73482.1 - 3.8 7.1 8.4 6.9 6.2 5.8 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger p450 PF00067.17 ETS73483.1 - 2e-53 181.5 0.0 2.5e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.16 ETS73484.1 - 3.7e-14 52.4 0.0 7.2e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETS73484.1 - 9.7e-05 21.8 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 ETS73484.1 - 0.00062 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain TPR_12 PF13424.1 ETS73484.1 - 0.036 13.9 0.4 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2450 PF10475.4 ETS73484.1 - 0.18 10.7 0.1 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Prefoldin_2 PF01920.15 ETS73485.1 - 6.4e-23 80.5 17.8 7.7e-23 80.2 12.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 ETS73485.1 - 0.00035 20.2 1.8 0.00035 20.2 1.2 2.5 2 1 0 2 2 2 1 Prefoldin subunit IncA PF04156.9 ETS73485.1 - 0.00078 19.0 15.1 0.0035 16.9 10.5 1.8 1 1 0 1 1 1 1 IncA protein Prefoldin_3 PF13758.1 ETS73485.1 - 0.0016 18.2 8.5 0.002 17.8 5.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.6 ETS73485.1 - 0.0031 16.2 12.6 0.0038 15.9 8.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein YgaB PF14182.1 ETS73485.1 - 0.014 15.6 5.5 0.014 15.6 3.8 2.4 2 1 0 2 2 2 0 YgaB-like protein PAD PF03068.10 ETS73485.1 - 0.022 13.2 0.9 0.024 13.0 0.6 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) KH_5 PF13184.1 ETS73485.1 - 0.03 14.1 2.6 0.03 14.1 1.8 1.8 1 1 1 2 2 2 0 NusA-like KH domain DUF4201 PF13870.1 ETS73485.1 - 0.06 12.7 13.4 0.59 9.5 9.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) MutS_IV PF05190.13 ETS73485.1 - 0.073 13.2 3.8 1.3 9.2 2.2 2.3 1 1 0 1 1 1 0 MutS family domain IV TPR_MLP1_2 PF07926.7 ETS73485.1 - 0.1 12.3 16.6 0.44 10.2 4.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliD_C PF07195.7 ETS73485.1 - 0.13 11.5 8.7 0.27 10.5 6.0 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DivIC PF04977.10 ETS73485.1 - 0.16 11.4 20.1 1 8.8 1.1 3.2 2 1 0 2 2 2 0 Septum formation initiator GAS PF13851.1 ETS73485.1 - 0.19 10.8 17.7 4.2 6.5 12.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IF3_C PF00707.17 ETS73485.1 - 0.26 11.0 5.0 0.071 12.8 0.8 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain CALCOCO1 PF07888.6 ETS73485.1 - 0.32 9.2 9.1 0.36 9.0 6.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_I PF06008.9 ETS73485.1 - 0.37 10.0 15.3 1.4 8.1 4.0 2.1 2 0 0 2 2 2 0 Laminin Domain I CDC37_N PF03234.9 ETS73485.1 - 0.45 10.8 10.2 0.57 10.4 7.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4164 PF13747.1 ETS73485.1 - 0.5 10.5 7.0 0.22 11.6 1.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) TcdA_TcdB PF12919.2 ETS73485.1 - 0.52 8.7 6.9 0.71 8.2 4.8 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MCPsignal PF00015.16 ETS73485.1 - 0.53 9.7 8.9 0.077 12.5 2.4 1.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ADIP PF11559.3 ETS73485.1 - 0.64 9.9 13.3 0.49 10.2 1.4 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Med28 PF11594.3 ETS73485.1 - 1.1 9.5 10.5 0.27 11.5 2.7 2.0 1 1 1 2 2 2 0 Mediator complex subunit 28 FlaC_arch PF05377.6 ETS73485.1 - 1.1 9.1 10.6 5.4 6.9 0.9 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 ETS73485.1 - 1.1 9.5 9.9 2.4 8.4 2.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4570 PF15134.1 ETS73485.1 - 1.4 8.8 6.5 3.8 7.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF1192 PF06698.6 ETS73485.1 - 1.5 8.7 9.9 1.1 9.1 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Occludin_ELL PF07303.8 ETS73485.1 - 1.5 9.6 8.1 1.1 10.0 1.5 2.1 2 0 0 2 2 2 0 Occludin homology domain Seryl_tRNA_N PF02403.17 ETS73485.1 - 1.5 8.8 15.7 60 3.7 10.9 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF848 PF05852.6 ETS73485.1 - 1.6 8.6 9.5 1.9 8.2 0.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin_1 PF12718.2 ETS73485.1 - 2.3 8.0 16.8 36 4.1 5.4 2.1 1 1 0 1 1 1 0 Tropomyosin like BRE1 PF08647.6 ETS73485.1 - 2.5 8.1 12.9 0.36 10.8 0.9 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ETRAMP PF09716.5 ETS73485.1 - 2.5 8.0 4.4 3.7 7.5 3.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF948 PF06103.6 ETS73485.1 - 2.6 7.9 7.3 3.7 7.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 ETS73485.1 - 2.7 7.6 16.3 5.5 6.6 2.6 2.1 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 ETS73485.1 - 3.1 8.3 12.1 7.8 7.0 3.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 ETS73485.1 - 3.6 5.7 12.7 4.2 5.5 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Cob_adeno_trans PF01923.13 ETS73485.1 - 4.6 6.9 8.2 5.9 6.6 0.5 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Atg14 PF10186.4 ETS73485.1 - 5.7 5.8 16.5 31 3.3 11.4 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 ETS73485.1 - 6.3 6.5 15.4 5.4 6.7 4.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 T2SM PF04612.7 ETS73485.1 - 6.5 6.5 8.4 1.8 8.3 2.2 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF2802 PF10975.3 ETS73485.1 - 7.9 6.3 9.7 5.2 6.9 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Val_tRNA-synt_C PF10458.4 ETS73485.1 - 8.9 6.4 13.3 2.6 8.2 0.5 3.2 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF3450 PF11932.3 ETS73485.1 - 9.8 5.3 13.7 3.4 6.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.5 ETS73485.1 - 9.9 6.2 11.8 1.5 8.9 1.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA PF00004.24 ETS73486.1 - 1.1e-42 145.3 0.0 1.9e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 ETS73486.1 - 3.9e-26 90.6 0.0 1.8e-25 88.5 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 ETS73486.1 - 3e-22 78.2 1.8 6.9e-22 77.1 0.8 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 ETS73486.1 - 8.8e-06 26.5 0.5 4.7e-05 24.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS73486.1 - 1.3e-05 24.4 0.0 2.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS73486.1 - 2e-05 24.3 0.0 0.00016 21.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS73486.1 - 2.2e-05 24.3 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS73486.1 - 3.2e-05 24.0 0.1 0.002 18.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS73486.1 - 4e-05 23.7 0.1 0.009 16.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 ETS73486.1 - 4.3e-05 23.0 0.0 9.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 ETS73486.1 - 4.5e-05 22.3 0.0 7.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 ETS73486.1 - 6.1e-05 22.5 1.4 0.15 11.4 0.1 3.5 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 ETS73486.1 - 9.7e-05 22.4 0.0 0.00063 19.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETS73486.1 - 0.00042 20.1 0.0 0.0014 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETS73486.1 - 0.00043 19.2 0.0 0.0008 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 ETS73486.1 - 0.00044 20.2 0.0 0.0022 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 ETS73486.1 - 0.0036 16.4 0.1 0.1 11.6 0.0 2.6 2 1 1 3 3 3 1 Zeta toxin AAA_24 PF13479.1 ETS73486.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS73486.1 - 0.0061 16.8 0.1 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS73486.1 - 0.022 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 ETS73486.1 - 0.025 13.7 0.1 0.066 12.3 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 ETS73486.1 - 0.025 14.2 0.0 0.35 10.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETS73486.1 - 0.027 14.1 0.2 0.13 11.9 0.0 2.1 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 ETS73486.1 - 0.036 13.1 0.0 6.1 5.8 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 ETS73486.1 - 0.041 13.1 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 ETS73486.1 - 0.045 12.6 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 ETS73486.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.1 ETS73486.1 - 0.085 12.7 0.1 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 ETS73486.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 ETS73486.1 - 0.13 11.7 0.0 0.4 10.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 ETS73486.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 ETS73486.1 - 0.13 11.6 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase 3Beta_HSD PF01073.14 ETS73488.1 - 0.0028 16.4 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3Beta_HSD PF01073.14 ETS73489.1 - 1.1e-16 60.4 0.0 1.3e-15 56.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS73489.1 - 2e-12 47.0 0.0 2.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS73489.1 - 9.1e-10 37.8 0.0 5.3e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 ETS73489.1 - 0.00043 19.2 0.0 0.00078 18.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS73489.1 - 0.00043 20.3 0.0 0.0025 17.8 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS73489.1 - 0.0011 18.8 0.0 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS73489.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 ETS73490.1 - 1.4e-28 99.6 30.3 1.4e-28 99.6 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73490.1 - 7.9e-10 37.8 13.5 7.9e-10 37.8 9.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter NmrA PF05368.8 ETS73491.1 - 2.7e-18 66.0 0.0 3.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS73491.1 - 4.7e-15 56.0 0.0 8.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS73491.1 - 0.0009 18.7 0.1 0.02 14.3 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family AP_endonuc_2 PF01261.19 ETS73491.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Cpn60_TCP1 PF00118.19 ETS73491.1 - 0.077 11.5 0.0 0.17 10.5 0.0 1.4 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family TGS PF02824.16 ETS73491.1 - 0.14 12.0 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 TGS domain MFS_1 PF07690.11 ETS73492.1 - 1.4e-16 60.2 12.7 1.8e-16 59.8 8.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.14 ETS73492.1 - 0.016 15.2 0.7 0.034 14.1 0.5 1.5 1 0 0 1 1 1 0 Cellulose binding domain FSH1 PF03959.8 ETS73493.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 ETS73493.1 - 3.9e-08 32.9 0.0 4.9e-06 26.1 0.0 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 ETS73493.1 - 1.9e-06 27.9 0.0 5.8e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73493.1 - 0.00021 21.0 0.0 0.0005 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fringe PF02434.11 ETS73494.1 - 7.1e-06 25.4 0.6 0.0042 16.3 0.5 3.1 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 ETS73494.1 - 0.00019 21.1 0.8 0.00056 19.5 0.6 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 ETS73494.1 - 0.028 14.2 0.4 0.063 13.1 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.7 ETS73494.1 - 0.036 13.6 0.4 0.066 12.8 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain DUF3106 PF11304.3 ETS73494.1 - 0.047 14.0 0.3 0.9 9.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) PAN_1 PF00024.21 ETS73494.1 - 0.067 12.9 0.7 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 PAN domain DLH PF01738.13 ETS73497.1 - 5e-28 97.8 0.0 6.5e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS73497.1 - 1.5e-09 37.7 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS73497.1 - 2.5e-05 24.2 0.0 0.0021 17.9 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73497.1 - 0.0011 18.5 0.0 0.011 15.3 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 ETS73497.1 - 0.01 15.5 0.0 0.71 9.5 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal 3Beta_HSD PF01073.14 ETS73498.1 - 5.3e-17 61.4 0.0 9.7e-17 60.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS73498.1 - 1.9e-15 56.9 0.0 2.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS73498.1 - 6.4e-14 51.4 0.0 2.2e-12 46.4 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS73498.1 - 3.2e-11 43.5 0.1 1.2e-10 41.6 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 ETS73498.1 - 1.8e-06 27.9 0.2 3.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS73498.1 - 1.3e-05 24.2 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS73498.1 - 5.9e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 ETS73498.1 - 0.00018 20.5 0.2 0.0005 19.0 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain COG5 PF10392.4 ETS73498.1 - 0.026 14.4 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DapB_N PF01113.15 ETS73498.1 - 0.029 14.2 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ETS73498.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 ETS73498.1 - 0.061 12.5 0.1 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_47 PF01532.15 ETS73499.1 - 1.1e-173 578.0 0.4 1.1e-173 578.0 0.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Fig1 PF12351.3 ETS73500.1 - 9.1e-57 191.8 4.5 9.1e-57 191.8 3.1 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 ETS73500.1 - 1.9e-07 30.8 9.2 2.5e-07 30.4 6.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 ETS73500.1 - 0.00036 19.5 7.6 0.00036 19.5 5.3 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 ETS73500.1 - 0.09 13.0 8.2 0.15 12.2 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF1673 PF07895.6 ETS73500.1 - 5.5 6.4 12.7 0.026 14.0 1.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) Pkinase PF00069.20 ETS73501.1 - 3.7e-26 91.8 0.0 6.8e-26 90.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS73501.1 - 2.3e-05 23.6 0.1 5.1e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 ETS73501.1 - 0.0031 16.5 0.2 0.0063 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS73501.1 - 0.046 13.4 2.6 0.45 10.2 0.8 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.17 ETS73502.1 - 1.3e-29 103.0 0.0 1.7e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.8 ETS73502.1 - 0.022 12.9 0.0 0.037 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) polyprenyl_synt PF00348.12 ETS73503.1 - 2.6e-53 180.5 0.1 3.3e-50 170.3 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 ETS73503.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 ETS73504.1 - 6.6e-34 116.6 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_3 PF13878.1 ETS73505.1 - 9.6e-07 28.2 0.4 1.9e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Peroxidase_2 PF01328.12 ETS73506.1 - 8.3e-10 37.8 0.1 4.4e-09 35.4 0.1 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.6 ETS73507.1 - 6.3e-12 45.1 7.3 1.3e-11 44.1 5.0 1.5 1 0 0 1 1 1 1 CFEM domain PsbH PF00737.15 ETS73507.1 - 8.9 5.9 7.1 0.82 9.2 1.2 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein GMC_oxred_N PF00732.14 ETS73508.1 - 2.7e-27 95.6 0.0 1.2e-16 60.7 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS73508.1 - 1.4e-24 87.0 0.0 2.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS73508.1 - 0.0002 21.2 0.0 0.009 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS73508.1 - 0.00035 20.5 0.8 0.0018 18.2 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS73508.1 - 0.00049 19.0 0.5 0.007 15.3 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.11 ETS73508.1 - 0.0042 16.5 0.3 0.013 14.9 0.2 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 ETS73508.1 - 0.017 13.9 0.9 0.029 13.2 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS73508.1 - 0.021 14.8 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS73508.1 - 0.11 11.4 0.2 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS73508.1 - 0.14 11.7 0.4 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 ETS73508.1 - 0.16 10.3 0.1 0.3 9.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 ETS73508.1 - 0.19 10.7 0.2 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GST_N PF02798.15 ETS73509.1 - 9.1e-17 61.0 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS73509.1 - 2.3e-14 53.3 0.0 3.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS73509.1 - 1.2e-11 44.4 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 ETS73509.1 - 0.12 12.8 0.1 0.34 11.3 0.0 1.7 1 1 1 2 2 2 0 MetRS-N binding domain FAD_binding_3 PF01494.14 ETS73510.1 - 5.8e-70 236.1 0.0 7.1e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 ETS73511.1 - 3.1e-07 30.1 10.1 5.5e-07 29.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 ETS73511.1 - 0.12 12.8 0.5 0.46 10.9 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_92 PF07971.7 ETS73512.1 - 1.9e-163 544.7 0.0 2.4e-162 541.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 O-FucT PF10250.4 ETS73513.1 - 0.00014 21.0 0.0 0.0025 16.9 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AvrE PF11725.3 ETS73513.1 - 0.28 8.1 0.0 0.36 7.7 0.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor Amidohydro_1 PF01979.15 ETS73514.1 - 5.4e-20 72.3 1.7 9.7e-18 64.8 1.2 2.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS73514.1 - 1.8e-18 67.5 0.0 4.9e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS73514.1 - 3.5e-12 45.9 0.1 9.7e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS73514.1 - 1.9e-07 30.6 0.3 0.0016 17.7 0.1 2.8 2 1 1 3 3 3 2 Amidohydrolase family DUF3425 PF11905.3 ETS73515.1 - 5e-32 110.6 0.0 1e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.12 ETS73515.1 - 0.012 15.8 2.5 0.023 14.9 1.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.20 ETS73516.1 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73516.1 - 1.4e-05 24.8 0.0 4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 KR domain MIP PF00230.15 ETS73517.1 - 9.2e-47 159.4 14.8 1.3e-46 158.9 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 ETS73518.1 - 2e-43 148.4 36.1 2e-43 148.4 25.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73518.1 - 6e-13 48.1 32.5 7.4e-12 44.5 22.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS73518.1 - 9.7e-05 20.7 1.0 0.00016 20.0 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CbiM PF01891.11 ETS73518.1 - 0.2 11.2 18.5 0.14 11.7 5.0 3.3 3 2 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region ABC_tran PF00005.22 ETS73519.1 - 1.9e-49 167.5 0.1 2.3e-23 83.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 ETS73519.1 - 3.9e-47 160.1 25.2 2.3e-28 98.7 3.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 ETS73519.1 - 3.7e-18 66.4 7.0 3.5e-07 30.4 0.7 4.2 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS73519.1 - 2.6e-09 36.7 0.5 0.0037 16.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 ETS73519.1 - 6.1e-09 36.1 0.6 0.0041 17.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 ETS73519.1 - 8.4e-09 34.9 0.1 0.0071 15.4 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 ETS73519.1 - 1.5e-08 34.1 2.5 0.011 14.9 0.1 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS73519.1 - 1.1e-07 32.3 0.1 0.0095 16.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS73519.1 - 5.2e-07 28.9 1.9 0.011 14.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 ETS73519.1 - 5.7e-07 29.3 0.2 0.0072 15.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 ETS73519.1 - 9.2e-07 28.5 0.3 0.00079 19.1 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 ETS73519.1 - 4.8e-06 26.7 1.5 0.078 13.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS73519.1 - 5.9e-06 25.7 3.9 0.021 14.3 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS73519.1 - 1.7e-05 25.6 0.0 0.38 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 ETS73519.1 - 2.9e-05 23.9 0.5 0.74 9.7 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 ETS73519.1 - 4e-05 23.2 4.6 0.02 14.3 0.3 2.3 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 ETS73519.1 - 5.7e-05 22.9 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase cobW PF02492.14 ETS73519.1 - 7.9e-05 22.1 1.6 0.088 12.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 ETS73519.1 - 0.00011 22.2 1.1 0.037 13.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS73519.1 - 0.00012 21.1 0.2 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 ETS73519.1 - 0.0002 21.0 0.1 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS73519.1 - 0.00077 19.7 0.1 0.72 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS73519.1 - 0.0018 17.7 3.0 0.13 11.7 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 ETS73519.1 - 0.0021 18.1 0.2 2.2 8.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 ETS73519.1 - 0.0026 17.3 0.4 2.5 7.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ETS73519.1 - 0.0027 17.4 1.4 2.3 7.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MobB PF03205.9 ETS73519.1 - 0.0032 17.1 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETS73519.1 - 0.0034 17.8 0.5 2.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 ETS73519.1 - 0.0056 16.5 1.5 1.9 8.3 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 ETS73519.1 - 0.0068 16.6 0.1 4.8 7.3 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS73519.1 - 0.018 14.6 0.3 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 ETS73519.1 - 0.027 14.3 0.3 6 6.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 ETS73519.1 - 0.032 12.8 0.4 0.13 10.8 0.1 2.0 3 0 0 3 3 2 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.12 ETS73519.1 - 0.034 13.6 2.9 5.5 6.4 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 ETS73519.1 - 0.043 13.1 2.8 1.8 7.8 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP-synt_ab PF00006.20 ETS73519.1 - 0.043 13.2 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 ETS73519.1 - 0.044 13.1 0.7 15 4.9 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 ETS73519.1 - 0.047 13.6 2.6 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETS73519.1 - 0.064 12.7 0.5 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 ETS73519.1 - 0.08 12.6 0.6 6.2 6.4 0.1 3.4 4 0 0 4 4 4 0 NTPase KaiC PF06745.8 ETS73519.1 - 0.096 11.7 0.2 2.5 7.1 0.1 2.7 3 0 0 3 3 3 0 KaiC Septin PF00735.13 ETS73519.1 - 0.12 11.3 1.3 7.8 5.4 0.1 2.2 2 0 0 2 2 2 0 Septin PRK PF00485.13 ETS73519.1 - 0.15 11.5 0.5 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2791 PF10923.3 ETS73519.1 - 0.16 10.5 0.0 9.5 4.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Sigma54_activat PF00158.21 ETS73519.1 - 0.19 11.2 0.1 20 4.6 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 ETS73519.1 - 0.26 10.4 0.4 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 ETS73519.1 - 0.32 9.9 0.8 12 4.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 ETS73519.1 - 0.36 9.9 1.5 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 ETS73519.1 - 6 6.6 5.5 19 5.0 0.1 2.9 4 0 0 4 4 2 0 Dynamin family Ank_2 PF12796.2 ETS73521.1 - 4.7e-14 52.4 0.1 2.7e-07 30.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS73521.1 - 1e-09 37.6 0.2 0.0098 15.6 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETS73521.1 - 2.3e-06 27.6 0.7 0.32 11.3 0.0 4.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73521.1 - 3.5e-06 26.7 0.9 0.26 11.6 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 ETS73521.1 - 0.00032 21.1 0.8 3.6 8.2 0.1 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 ETS73521.1 - 0.0037 17.0 0.0 0.24 11.2 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) ADH_N PF08240.7 ETS73522.1 - 1.1e-25 89.5 2.3 2.5e-25 88.3 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73522.1 - 8e-16 57.7 0.0 1.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 ETS73522.1 - 0.043 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 ETS73522.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 ETS73522.1 - 0.1 13.5 0.0 0.17 12.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 ETS73523.1 - 1.9e-34 119.5 0.2 2.2e-34 119.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS73523.1 - 2.1e-34 118.8 6.6 2.7e-34 118.4 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73523.1 - 1.9e-17 63.5 2.4 2.6e-17 63.0 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS73523.1 - 4.8e-05 22.9 1.2 0.00016 21.1 0.8 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS73523.1 - 0.055 13.2 0.8 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 ETS73524.1 - 4.1e-25 88.1 0.3 6e-25 87.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS73525.1 - 5.4e-90 302.1 23.9 6.8e-90 301.8 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73525.1 - 6.2e-14 51.4 38.3 8.3e-14 51.0 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.19 ETS73526.1 - 5e-25 87.6 0.1 8.5e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETS73526.1 - 3.5e-06 26.4 2.8 0.00052 19.4 0.0 2.7 3 0 0 3 3 3 2 N-terminal domain of DJ-1_PfpI family APH PF01636.18 ETS73527.1 - 1.1e-08 35.1 0.1 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 ETS73528.1 - 2.7e-21 76.5 0.0 1e-18 68.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS73528.1 - 1.3e-12 47.2 0.0 7.9e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 ETS73528.1 - 2.6e-08 32.5 0.0 9e-07 27.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS73528.1 - 0.00028 20.8 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 ETS73529.1 - 6.3e-05 22.9 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF4291 PF14124.1 ETS73529.1 - 0.031 13.9 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Fungal_trans_2 PF11951.3 ETS73530.1 - 8.1e-32 110.2 0.0 1.7e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73530.1 - 1.3e-08 34.6 12.0 2.1e-08 33.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 ETS73530.1 - 0.075 12.7 4.6 0.19 11.4 3.2 1.8 1 0 0 1 1 1 0 AT hook motif ADH_zinc_N PF00107.21 ETS73531.1 - 2.1e-18 66.1 0.0 3.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73531.1 - 1e-05 26.4 0.0 2.8e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 ETS73531.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Myb_DNA-bind_6 PF13921.1 ETS73532.1 - 5.8e-14 51.9 2.3 3.9e-08 33.2 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS73532.1 - 3.8e-07 30.0 7.1 9.5e-05 22.3 0.1 3.3 3 1 0 3 3 3 2 Myb-like DNA-binding domain FMO-like PF00743.14 ETS73533.1 - 1.2e-43 149.1 0.0 4e-22 78.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS73533.1 - 2.4e-18 66.9 0.1 3.5e-17 63.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS73533.1 - 5e-10 39.5 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS73533.1 - 2.4e-08 33.8 0.1 2.1e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS73533.1 - 7.4e-08 31.6 2.4 6.1e-06 25.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS73533.1 - 8e-07 28.2 0.8 1.8e-05 23.8 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS73533.1 - 1.5e-06 27.6 0.0 0.00032 19.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 ETS73533.1 - 1.6e-06 27.9 2.3 2.9e-05 23.8 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS73533.1 - 9.1e-05 21.6 0.0 0.00026 20.1 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETS73533.1 - 0.00027 21.2 3.2 0.0033 17.7 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS73533.1 - 0.0037 16.3 0.1 0.0073 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS73533.1 - 0.005 15.9 0.1 0.022 13.8 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 ETS73533.1 - 0.017 15.2 0.0 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 ETS73533.1 - 0.023 13.5 0.1 0.047 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS73533.1 - 0.031 12.7 0.2 0.056 11.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 ETS73533.1 - 0.055 12.3 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 ETS73533.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 ETS73533.1 - 0.15 11.7 0.2 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 ETS73534.1 - 1.2e-15 57.0 21.7 6.3e-13 48.1 6.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS73534.1 - 0.0014 18.4 1.1 0.0042 16.8 0.6 2.0 2 0 0 2 2 2 1 MFS_1 like family MFS_1 PF07690.11 ETS73535.1 - 0.0087 14.8 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 ETS73536.1 - 5.4e-53 180.2 0.2 6.6e-53 180.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family peroxidase PF00141.18 ETS73537.1 - 1.1e-21 77.4 0.1 1.6e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_61 PF03443.9 ETS73538.1 - 4.8e-61 206.3 0.1 4.8e-61 206.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Methyltransf_18 PF12847.2 ETS73539.1 - 3.4e-11 43.7 0.0 5.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73539.1 - 1.2e-10 41.6 0.0 2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS73539.1 - 5.9e-10 39.1 0.0 9.5e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS73539.1 - 7.9e-10 38.7 0.1 1.8e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73539.1 - 2.3e-07 30.5 0.0 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73539.1 - 7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS73539.1 - 8.8e-06 24.9 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS73539.1 - 0.00047 20.5 0.0 0.00081 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 ETS73539.1 - 0.0027 16.7 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS73539.1 - 0.0053 15.9 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 ETS73539.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.9 ETS73539.1 - 0.046 13.1 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 ETS73539.1 - 0.071 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.14 ETS73539.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 ETS73539.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ELYS PF13934.1 ETS73540.1 - 5.2e-56 189.9 0.0 6.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 ETS73541.1 - 6.1e-75 251.2 15.0 2.8e-74 249.0 10.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS73541.1 - 2.3e-26 92.0 0.0 1.3e-25 89.6 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS73541.1 - 4.4e-12 46.5 6.9 2.3e-05 24.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS73541.1 - 1.4e-07 32.0 14.1 1.4e-07 32.0 9.8 7.1 3 2 2 5 5 3 1 AAA domain AAA_29 PF13555.1 ETS73541.1 - 0.00033 20.1 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.7 ETS73541.1 - 0.0013 18.5 1.8 0.0013 18.5 1.3 9.1 4 2 5 9 9 9 1 Laminin Domain II DivIC PF04977.10 ETS73541.1 - 0.002 17.5 5.8 0.002 17.5 4.0 11.9 6 4 8 14 14 14 1 Septum formation initiator Tektin PF03148.9 ETS73541.1 - 0.0021 16.6 18.8 0.0021 16.6 13.0 7.1 3 2 3 7 7 7 1 Tektin family Filament PF00038.16 ETS73541.1 - 0.0038 16.7 50.8 0.0038 16.7 35.2 5.6 3 2 0 3 3 2 1 Intermediate filament protein Reo_sigmaC PF04582.7 ETS73541.1 - 0.047 12.8 32.6 0.019 14.1 0.9 4.7 3 2 1 4 4 4 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 ETS73541.1 - 0.51 10.1 7.2 6.3 6.6 0.0 5.0 4 1 1 5 5 5 0 DASH complex subunit Dam1 AAA_13 PF13166.1 ETS73541.1 - 3.2 6.1 120.0 0.054 11.9 20.5 6.1 3 2 2 5 5 5 0 AAA domain Beta-lactamase PF00144.19 ETS73544.1 - 1.9e-59 201.3 0.3 2.3e-59 201.0 0.2 1.0 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_3 PF00933.16 ETS73546.1 - 8.7e-84 281.0 0.0 1.3e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS73546.1 - 3.4e-49 167.4 0.3 7.2e-49 166.3 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS73546.1 - 4.7e-21 74.5 0.0 9.1e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_61 PF03443.9 ETS73547.1 - 1.4e-49 168.8 1.9 1.6e-49 168.6 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_7 PF00840.15 ETS73548.1 - 3e-84 282.9 25.6 9.8e-29 99.9 1.3 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 Nuc_sug_transp PF04142.10 ETS73549.1 - 0.28 10.2 4.6 0.35 9.9 0.2 2.0 1 1 0 2 2 2 0 Nucleotide-sugar transporter DUF1772 PF08592.6 ETS73549.1 - 0.64 9.7 5.3 0.11 12.2 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4267 PF14087.1 ETS73550.1 - 6.9e-17 61.0 3.3 8.5e-17 60.7 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PX PF00787.19 ETS73551.1 - 1e-15 57.5 0.0 1.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 ETS73551.1 - 4.8e-13 48.5 6.8 1.2e-12 47.3 4.7 1.7 1 0 0 1 1 1 1 SNARE domain IncA PF04156.9 ETS73551.1 - 1.3 8.5 7.2 0.91 9.0 3.7 1.7 2 0 0 2 2 2 0 IncA protein GMC_oxred_N PF00732.14 ETS73552.1 - 1.6e-60 204.8 0.0 2e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS73552.1 - 2.3e-31 109.0 0.1 3.6e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS73552.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETS73552.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_11 PF08241.7 ETS73553.1 - 2.4e-07 31.1 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73553.1 - 2e-06 28.0 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73553.1 - 5.6e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73553.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 ETS73553.1 - 0.059 13.0 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.15 ETS73554.1 - 9.5e-50 169.4 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 ETS73554.1 - 7.2e-07 28.3 0.0 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Fungal_trans PF04082.13 ETS73556.1 - 3.5e-13 49.0 0.2 6.1e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73556.1 - 1.3e-08 34.5 10.7 2.1e-08 33.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS73557.1 - 3.7e-14 52.2 35.9 3.7e-14 52.2 24.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Innexin PF00876.13 ETS73557.1 - 0.036 13.1 0.1 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Innexin p450 PF00067.17 ETS73558.1 - 1.3e-50 172.3 0.0 2.4e-50 171.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 ETS73559.1 - 6.3e-10 38.2 2.5 6.9e-10 38.0 0.4 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MGC-24 PF05283.6 ETS73559.1 - 0.00029 20.6 5.7 0.0004 20.2 4.0 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 ETS73559.1 - 0.00048 19.8 0.0 0.00063 19.4 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family VSP PF03302.8 ETS73559.1 - 0.0013 17.4 1.6 0.0018 17.0 1.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4448 PF14610.1 ETS73559.1 - 0.0028 17.1 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 ETS73559.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.7 ETS73559.1 - 0.0082 15.5 0.4 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor CcoS PF03597.10 ETS73559.1 - 0.028 13.8 0.5 0.049 13.0 0.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Med3 PF11593.3 ETS73559.1 - 0.3 10.2 13.3 0.68 9.1 9.1 1.5 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal EII-Sor PF03609.9 ETS73559.1 - 0.35 10.1 2.4 0.49 9.6 1.7 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component GRA6 PF05084.8 ETS73559.1 - 0.53 9.7 5.3 0.11 12.0 0.6 1.9 1 1 1 2 2 2 0 Granule antigen protein (GRA6) SSP160 PF06933.6 ETS73559.1 - 1.7 6.5 21.3 2.3 6.1 14.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly_transf_sug PF04488.10 ETS73560.1 - 3.3e-10 40.2 0.0 8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETS73560.1 - 0.0002 20.6 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PAN_2 PF08276.6 ETS73561.1 - 1.5e-06 27.9 1.8 0.29 10.9 0.0 3.5 3 0 0 3 3 3 3 PAN-like domain PAN_4 PF14295.1 ETS73561.1 - 0.0011 18.6 11.3 0.38 10.4 0.1 3.8 3 0 0 3 3 3 2 PAN domain F-box-like PF12937.2 ETS73562.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS73562.1 - 0.036 13.7 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box domain AA_permease_2 PF13520.1 ETS73563.1 - 3e-43 147.9 54.2 3.8e-43 147.6 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS73563.1 - 9.2e-29 100.1 50.5 1.2e-28 99.7 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4200 PF13863.1 ETS73564.1 - 2.1 8.2 8.0 0.083 12.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NAD_synthase PF02540.12 ETS73565.1 - 3.1e-23 81.9 0.0 9.3e-23 80.3 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 ETS73565.1 - 5.5e-21 74.7 0.0 9.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DBINO PF13892.1 ETS73565.1 - 0.12 12.4 0.1 4.8 7.2 0.1 2.3 2 0 0 2 2 2 0 DNA-binding domain Glyco_hydro_3 PF00933.16 ETS73566.1 - 5.5e-92 307.9 0.0 8.1e-92 307.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS73566.1 - 1.3e-56 191.6 0.3 9.5e-56 188.8 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS73566.1 - 2.8e-14 52.8 0.0 5.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.6 ETS73567.1 - 3.6e-34 117.9 0.0 5.9e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTA2 PF13095.1 ETS73571.1 - 7.1e-20 71.4 0.0 1.6e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 NAD_binding_10 PF13460.1 ETS73572.1 - 3.5e-12 46.6 0.0 6.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS73572.1 - 9.7e-09 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS73572.1 - 4e-05 23.1 0.0 7.5e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS73572.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS73572.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase adh_short PF00106.20 ETS73573.1 - 4.2e-14 52.8 0.0 6.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73573.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73573.1 - 0.003 17.0 0.0 0.0072 15.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS73573.1 - 0.0085 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Peptidase_S41 PF03572.13 ETS73573.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S41 Glyco_hydro_1 PF00232.13 ETS73574.1 - 2.3e-142 474.4 1.7 2.8e-142 474.1 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fringe PF02434.11 ETS73576.1 - 0.0002 20.6 0.5 0.0021 17.3 0.3 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 ETS73576.1 - 0.0068 16.0 0.1 0.027 14.0 0.0 2.0 1 1 1 2 2 2 1 Galactosyltransferase PAN_4 PF14295.1 ETS73576.1 - 0.03 14.0 1.5 0.069 12.8 1.1 1.6 1 0 0 1 1 1 0 PAN domain PAP2_3 PF14378.1 ETS73578.1 - 3.5e-18 65.8 19.8 5.4e-15 55.4 1.7 2.7 3 0 0 3 3 3 2 PAP2 superfamily PAP2_C PF14360.1 ETS73578.1 - 0.024 14.8 0.3 0.024 14.8 0.2 2.9 5 0 0 5 5 5 0 PAP2 superfamily C-terminal RtcB PF01139.12 ETS73578.1 - 0.041 12.8 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Pex14_N PF04695.8 ETS73578.1 - 0.073 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3328 PF11807.3 ETS73579.1 - 1.1e-25 90.5 0.5 1.9e-25 89.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APH PF01636.18 ETS73580.1 - 1.9e-17 63.8 0.1 3.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS73580.1 - 0.00015 21.3 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YfcL PF08891.6 ETS73580.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 YfcL protein Glycoprotein_B PF00606.13 ETS73581.1 - 0.0055 14.7 0.9 0.0079 14.2 0.6 1.2 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Macoilin PF09726.4 ETS73581.1 - 0.1 10.8 0.3 0.089 11.0 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Orbi_VP3 PF01700.11 ETS73581.1 - 1 6.7 3.7 4.2 4.6 1.9 1.9 1 1 1 2 2 2 0 Orbivirus VP3 (T2) protein p450 PF00067.17 ETS73583.1 - 6.9e-52 176.4 0.0 8.9e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3433 PF11915.3 ETS73584.1 - 1.5e-32 111.6 18.1 2.4e-18 66.0 2.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) PrgI PF12666.2 ETS73584.1 - 9.9 6.3 6.5 1.3 9.1 0.4 2.6 2 1 1 3 3 3 0 PrgI family protein Nha1_C PF08619.5 ETS73585.1 - 2.8e-81 274.0 53.6 3e-76 257.4 30.7 2.3 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 ETS73585.1 - 5e-67 226.0 20.8 6e-67 225.8 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.1 ETS73585.1 - 0.043 13.5 0.2 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain Tom22 PF04281.8 ETS73586.1 - 2e-48 163.3 0.3 2.5e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Pectate_lyase_3 PF12708.2 ETS73587.1 - 2.6e-34 119.3 9.2 2e-22 80.4 1.7 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 ETS73587.1 - 0.2 11.3 8.1 0.03 14.0 1.3 2.6 3 0 0 3 3 3 0 Right handed beta helix region FAD_binding_4 PF01565.18 ETS73588.1 - 9.2e-14 51.1 4.6 9.2e-14 51.1 3.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS73588.1 - 0.00023 20.9 0.0 0.00056 19.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF2079 PF09852.4 ETS73589.1 - 0.98 8.0 10.2 2.8 6.5 0.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) Ank_2 PF12796.2 ETS73591.1 - 0.015 15.6 0.0 0.04 14.2 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS73591.1 - 0.077 13.2 0.0 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 ETS73591.1 - 0.11 12.3 0.0 30 4.6 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_23 PF13489.1 ETS73592.1 - 5.6e-07 29.4 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73592.1 - 1.7e-06 27.7 0.0 4.7e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73592.1 - 0.00014 22.3 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS73592.1 - 0.004 17.4 0.0 0.017 15.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS73592.1 - 0.0046 16.9 0.1 0.02 14.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73592.1 - 0.0047 17.3 0.0 0.026 14.9 0.0 2.3 3 1 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS73592.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ETS73592.1 - 0.024 15.1 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 ETS73592.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TIR_2 PF13676.1 ETS73592.1 - 0.14 12.3 0.1 5.6 7.1 0.0 2.8 3 0 0 3 3 3 0 TIR domain CheR PF01739.13 ETS73592.1 - 0.15 11.3 0.0 0.69 9.1 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ebola_NP PF05505.7 ETS73593.1 - 0.96 7.4 10.6 0.023 12.7 2.5 1.7 2 0 0 2 2 2 0 Ebola nucleoprotein DUF4449 PF14613.1 ETS73594.1 - 1.4e-68 229.9 2.7 1.4e-68 229.9 1.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF4346 PF14251.1 ETS73594.1 - 0.044 13.5 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) PIF1 PF05970.9 ETS73595.1 - 2.7e-62 210.8 0.1 7.1e-49 166.6 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 ETS73595.1 - 2.2e-18 66.5 0.0 4.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS73595.1 - 5.3e-08 33.0 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS73595.1 - 1e-05 25.1 0.1 2.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 ETS73595.1 - 6.5e-05 23.1 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS73595.1 - 9.3e-05 22.4 0.2 0.00025 21.1 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 ETS73595.1 - 0.00014 21.9 0.0 0.00059 19.9 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 ETS73595.1 - 0.00021 19.2 0.0 0.00066 17.5 0.0 1.7 2 0 0 2 2 2 1 Helicase IstB_IS21 PF01695.12 ETS73595.1 - 0.00042 19.7 0.1 0.013 14.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.11 ETS73595.1 - 0.0026 17.0 0.0 0.011 14.9 0.0 2.1 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.22 ETS73595.1 - 0.0052 17.0 4.4 0.023 14.9 0.0 3.0 1 1 1 2 2 2 1 ABC transporter T2SE PF00437.15 ETS73595.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 ETS73595.1 - 0.0067 15.9 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 ETS73595.1 - 0.031 13.9 0.2 0.27 10.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.11 ETS73595.1 - 0.044 12.5 0.0 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase AAA_25 PF13481.1 ETS73595.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETS73595.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 ETS73595.1 - 0.066 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS73595.1 - 0.14 12.9 0.0 0.32 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MAPEG PF01124.13 ETS73596.1 - 1.9e-14 53.3 4.2 2.3e-14 53.1 2.9 1.1 1 0 0 1 1 1 1 MAPEG family DUF1308 PF07000.6 ETS73597.1 - 4.3e-42 144.0 0.0 6.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Recep_L_domain PF01030.19 ETS73599.1 - 0.00027 20.8 1.3 0.57 10.1 0.0 3.9 1 1 3 4 4 4 2 Receptor L domain IncA PF04156.9 ETS73599.1 - 0.004 16.7 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 IncA protein LRR_5 PF13306.1 ETS73599.1 - 0.033 13.8 0.4 0.16 11.6 0.3 1.9 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) Rifin_STEVOR PF02009.11 ETS73599.1 - 0.044 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DNA_ligase_A_M PF01068.16 ETS73600.1 - 2.9e-44 150.8 0.1 9.5e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETS73600.1 - 2e-38 131.9 0.0 4.9e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETS73600.1 - 4.7e-13 49.3 0.0 1.7e-12 47.5 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 ETS73600.1 - 2.8e-09 37.0 0.1 4.3e-07 29.9 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 ETS73600.1 - 0.0068 16.1 0.0 0.15 11.7 0.0 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.3 ETS73600.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV PTCB-BRCT PF12738.2 ETS73600.1 - 0.019 14.8 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain UPRTase PF14681.1 ETS73601.1 - 2.5e-73 245.6 0.0 2.9e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 ETS73601.1 - 1.9e-06 27.6 0.0 3.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 ETS73601.1 - 0.012 14.7 0.4 0.12 11.4 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI CRCB PF02537.10 ETS73602.1 - 6.6e-29 100.1 19.5 2.7e-18 65.9 4.9 3.5 3 1 0 3 3 3 3 CrcB-like protein PEHE PF15275.1 ETS73602.1 - 0.039 14.4 0.6 0.039 14.4 0.5 1.5 2 0 0 2 2 2 0 PEHE domain DUF2968 PF11180.3 ETS73602.1 - 0.074 12.4 4.0 0.12 11.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF2201_N PF13203.1 ETS73602.1 - 0.11 11.6 1.3 0.16 11.0 0.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain YjeF_N PF03853.10 ETS73603.1 - 6.7e-37 126.6 0.1 9.3e-37 126.2 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 ETS73603.1 - 4.8e-14 52.7 0.8 1.3e-13 51.3 0.5 1.8 1 0 0 1 1 1 1 FDF domain DEC-1_N PF04625.8 ETS73603.1 - 0.019 13.6 6.9 0.035 12.7 4.8 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aldo_ket_red PF00248.16 ETS73604.1 - 6.5e-61 205.6 0.0 8.1e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 ETS73605.1 - 4.5e-44 151.0 0.4 6e-44 150.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase PRK PF00485.13 ETS73606.1 - 2.2e-57 193.7 0.0 3.2e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 ETS73606.1 - 6.6e-41 139.8 0.0 9.7e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 ETS73606.1 - 5.7e-10 40.0 0.1 1.2e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS73606.1 - 1e-05 25.8 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS73606.1 - 0.00013 21.9 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 ETS73606.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 ETS73606.1 - 0.0023 18.2 0.3 0.049 13.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 ETS73606.1 - 0.0042 16.2 0.0 0.0082 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 ETS73606.1 - 0.0093 16.1 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 ETS73606.1 - 0.0095 15.6 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 ETS73606.1 - 0.011 14.5 0.0 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 ETS73606.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 ETS73606.1 - 0.03 14.3 0.1 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS73606.1 - 0.073 12.6 0.1 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 ETS73606.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 ETS73606.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 ETS73606.1 - 0.16 11.3 0.1 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLTH PF10607.4 ETS73607.1 - 1.3e-32 112.4 0.0 1.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 ETS73607.1 - 8.6e-07 28.5 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 LisH ATP-synt_DE PF00401.15 ETS73607.1 - 0.1 12.5 0.1 2 8.3 0.0 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ETC_C1_NDUFA4 PF04800.7 ETS73608.1 - 9.5e-38 128.1 0.4 1.5e-37 127.4 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Mucin PF01456.12 ETS73608.1 - 0.94 9.2 9.8 1.3 8.7 6.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein F1F0-ATPsyn_F PF10791.4 ETS73609.1 - 1.2e-41 140.8 0.1 1.3e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF3716 PF12511.3 ETS73611.1 - 4.4e-11 42.2 3.5 6.5e-11 41.6 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Gp37_Gp68 PF07505.6 ETS73611.1 - 0.034 13.2 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 MCM PF00493.18 ETS73612.1 - 1.2e-136 454.9 0.8 1.2e-136 454.9 0.6 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 ETS73612.1 - 6.4e-22 78.3 0.0 2.6e-21 76.3 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS73612.1 - 3.2e-07 29.7 0.0 1.1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS73612.1 - 0.001 18.7 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS73612.1 - 0.0012 18.3 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 ETS73612.1 - 0.019 14.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2360 PF10152.4 ETS73612.1 - 0.27 11.5 8.2 1.6 9.0 0.1 3.5 4 1 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4118 PF13493.1 ETS73613.1 - 0.078 13.1 1.9 0.11 12.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Glycoprotein_B PF00606.13 ETS73613.1 - 0.29 9.1 3.0 0.31 8.9 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF1593 PF07632.6 ETS73614.1 - 1.1e-93 313.3 0.0 1.4e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 ETS73614.1 - 0.0012 17.3 0.0 0.0019 16.6 0.0 1.3 1 0 0 1 1 1 1 REJ domain DUF4360 PF14273.1 ETS73615.1 - 7.4e-53 178.9 3.2 3.2e-52 176.8 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4360) IBR PF01485.16 ETS73616.1 - 1.9e-17 62.8 19.4 2.1e-10 40.3 4.2 5.8 6 1 1 7 7 7 3 IBR domain DUF1335 PF07056.6 ETS73616.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) FAD_binding_4 PF01565.18 ETS73617.1 - 2.5e-23 82.1 2.1 4.4e-23 81.2 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS73617.1 - 0.00014 21.6 0.0 0.00046 20.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Dabb PF07876.7 ETS73618.1 - 7.5e-21 74.3 0.1 1.1e-18 67.4 0.0 2.1 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain RTA1 PF04479.8 ETS73620.1 - 1.3e-07 31.3 8.9 3.4e-07 29.9 5.7 2.0 1 1 1 2 2 2 1 RTA1 like protein DUF3810 PF12725.2 ETS73620.1 - 0.11 11.4 0.7 0.16 10.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MerC PF03203.9 ETS73620.1 - 0.25 11.6 5.5 0.13 12.5 1.5 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein MFS_1 PF07690.11 ETS73622.1 - 1.8e-28 99.2 72.0 1.7e-17 63.1 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS73622.1 - 0.00021 19.8 14.7 0.00021 19.8 10.2 2.9 1 1 0 2 2 2 1 MFS/sugar transport protein HeLo PF14479.1 ETS73623.1 - 1.2 8.7 5.4 0.33 10.6 1.4 1.7 2 0 0 2 2 2 0 Prion-inhibition and propagation MIP-T3 PF10243.4 ETS73623.1 - 7.6 4.8 19.7 9.1 4.6 13.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MUG2_C PF08593.5 ETS73625.1 - 0.25 11.6 3.1 0.55 10.4 2.1 1.6 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal Zn_clus PF00172.13 ETS73626.1 - 6.1e-08 32.4 10.1 1e-07 31.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS73626.1 - 3.2e-05 22.6 0.0 7.1e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLDc PF00614.17 ETS73628.1 - 5.7e-15 54.5 2.0 8.1e-07 28.6 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 ETS73628.1 - 1.2e-11 44.4 0.0 5e-06 26.2 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Glyco_hydro_cc PF11790.3 ETS73629.1 - 2e-49 168.1 0.0 2.4e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TPR_11 PF13414.1 ETS73630.1 - 6.1e-11 41.8 0.8 6.1e-11 41.8 0.5 2.3 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 ETS73630.1 - 1.6e-06 27.9 0.5 3.9e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS73630.1 - 0.00027 20.5 0.8 0.63 10.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS73630.1 - 0.0012 18.3 2.0 0.61 9.8 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS73630.1 - 0.0045 17.2 0.4 0.018 15.3 0.3 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS73630.1 - 0.0072 16.4 1.5 0.014 15.5 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETS73630.1 - 0.0074 16.0 0.1 7.3 6.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat YukC PF10140.4 ETS73630.1 - 0.0097 14.5 0.5 0.014 13.9 0.4 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC ATP-synt_D PF01813.12 ETS73630.1 - 0.2 11.2 3.2 0.4 10.2 0.3 2.2 2 0 0 2 2 2 0 ATP synthase subunit D HAD_2 PF13419.1 ETS73631.1 - 1.8e-11 44.5 0.0 4.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS73631.1 - 9.4e-05 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS73631.1 - 0.00065 20.1 0.0 0.18 12.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 ETS73632.1 - 5.8e-09 35.0 1.8 1.1e-08 34.0 1.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2132 PF09905.4 ETS73632.1 - 0.029 14.3 0.2 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) TFIIA PF03153.8 ETS73632.1 - 0.43 10.4 4.8 0.24 11.2 0.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 ETS73633.1 - 1.1e-22 79.0 1.5 3.8e-05 23.3 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat Acyltransferase PF01553.16 ETS73634.1 - 2e-16 59.6 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 ETS73635.1 - 1.5e-26 91.8 0.0 6.7e-26 89.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Beta-lactamase PF00144.19 ETS73636.1 - 5.1e-31 107.9 0.1 9.3e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase XAP5 PF04921.9 ETS73637.1 - 2.3e-77 259.7 2.1 2.3e-77 259.7 1.5 1.5 2 0 0 2 2 2 1 XAP5, circadian clock regulator Ribosomal_60s PF00428.14 ETS73637.1 - 6.8 7.1 18.6 0.051 13.9 3.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 ETS73637.1 - 10 5.7 12.3 0.9 9.1 5.4 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region HET PF06985.6 ETS73638.1 - 2.4e-21 76.3 0.8 4e-21 75.6 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS73639.1 - 1.6e-41 142.2 29.6 2.4e-40 138.3 9.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS73639.1 - 0.024 14.3 5.6 0.11 12.2 0.8 3.3 3 0 0 3 3 3 0 MFS_1 like family Sec62 PF03839.11 ETS73639.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Fip1 PF05182.8 ETS73640.1 - 1.1e-20 72.6 0.9 2.2e-20 71.6 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif Metal_resist PF13801.1 ETS73640.1 - 6.8 6.7 7.7 2.3 8.2 3.0 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Nucleoporin_FG PF13634.1 ETS73641.1 - 2.9e-12 46.8 109.1 2.2e-08 34.2 40.3 3.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region Not3 PF04065.10 ETS73641.1 - 0.0082 15.4 0.6 0.024 13.8 0.4 1.7 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Fib_alpha PF08702.5 ETS73641.1 - 0.14 12.3 0.9 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FoP_duplication PF13865.1 ETS73641.1 - 1.2 9.6 4.8 10 6.6 0.0 3.3 3 1 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.11 ETS73642.1 - 1.6e-18 66.5 13.5 8.4e-18 64.1 9.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 ETS73643.1 - 1.5e-11 43.6 30.1 2.9e-06 26.2 11.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily SNO PF01174.14 ETS73644.1 - 2.7e-54 183.6 0.0 1.5e-43 148.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 ETS73644.1 - 1.7e-09 37.4 0.0 4.6e-08 32.8 0.0 2.3 2 1 1 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 ETS73644.1 - 8.3e-05 22.1 0.0 0.00068 19.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 ETS73644.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS73644.1 - 0.00028 20.3 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 ETS73644.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 SOR_SNZ PF01680.12 ETS73645.1 - 6.4e-106 352.5 4.0 8.9e-106 352.1 2.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 ETS73645.1 - 5.5e-09 35.4 3.0 3.2e-06 26.3 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 ETS73645.1 - 0.0016 17.3 1.0 0.58 8.9 0.0 2.7 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.9 ETS73645.1 - 0.0027 16.6 0.8 0.05 12.5 0.0 2.7 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 ETS73645.1 - 0.0039 16.2 0.1 0.04 12.9 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 ETS73645.1 - 0.0058 15.9 0.5 0.13 11.5 0.0 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 ETS73645.1 - 0.045 12.8 7.8 0.03 13.4 0.5 2.5 2 1 0 2 2 2 0 Nitronate monooxygenase DUF4398 PF14346.1 ETS73645.1 - 0.051 13.6 0.1 0.051 13.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TMP-TENI PF02581.12 ETS73645.1 - 0.12 11.4 2.0 1.3 8.1 0.0 3.0 4 0 0 4 4 4 0 Thiamine monophosphate synthase/TENI SKG6 PF08693.5 ETS73646.1 - 0.053 12.8 0.0 0.053 12.8 0.0 2.3 2 1 0 2 2 2 0 Transmembrane alpha-helix domain DUF2353 PF09789.4 ETS73649.1 - 0.0023 17.2 0.1 0.0023 17.2 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DPRP PF04244.8 ETS73649.1 - 0.19 11.2 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein Fungal_trans PF04082.13 ETS73650.1 - 0.00013 20.9 0.1 0.00021 20.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.6 ETS73651.1 - 3.1e-13 49.3 12.2 6.7e-13 48.2 8.5 1.6 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 ETS73652.1 - 1.9e-26 92.9 0.0 4.8e-17 62.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS73652.1 - 5.8e-26 91.5 0.0 1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 ETS73652.1 - 5.7e-05 23.0 0.2 0.00017 21.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS73652.1 - 0.0027 16.6 0.0 0.007 15.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 ETS73652.1 - 0.0066 15.9 0.4 0.019 14.3 0.3 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETS73652.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS73652.1 - 0.075 11.8 1.5 0.11 11.2 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 ETS73652.1 - 0.078 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 ETS73652.1 - 0.08 11.3 0.3 0.11 10.9 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 ETS73652.1 - 0.24 11.0 0.2 0.41 10.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 ETS73653.1 - 2.3e-72 244.0 19.5 2.8e-72 243.7 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73653.1 - 1.5e-23 83.1 30.8 1.2e-19 70.3 7.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 ETS73654.1 - 1.3e-17 64.2 0.0 2.9e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS73656.1 - 1.5e-38 132.4 46.9 1.3e-35 122.7 18.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 ETS73656.1 - 0.012 15.1 2.3 0.012 15.1 1.6 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Cu-oxidase_3 PF07732.10 ETS73657.1 - 3.1e-38 130.1 2.6 8.4e-38 128.7 1.8 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS73657.1 - 4e-37 126.7 10.0 8.6e-37 125.7 0.5 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS73657.1 - 4.8e-35 120.8 2.8 4.7e-33 114.3 0.7 2.5 2 0 0 2 2 2 2 Multicopper oxidase CENP-L PF13092.1 ETS73660.1 - 4.8e-29 101.2 0.0 7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ank_2 PF12796.2 ETS73661.1 - 3.5e-14 52.8 0.4 4.8e-05 23.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS73661.1 - 2.6e-12 46.9 0.9 3.3e-07 30.6 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS73661.1 - 1.9e-10 39.9 1.2 0.0023 17.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETS73661.1 - 3.2e-10 39.9 0.1 0.002 18.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73661.1 - 7e-09 35.0 0.1 0.096 12.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 ETS73661.1 - 0.0014 18.2 0.2 0.0014 18.2 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain Seryl_tRNA_N PF02403.17 ETS73661.1 - 0.3 11.1 8.2 6.5 6.8 5.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 ETS73661.1 - 0.31 10.9 6.5 0.69 9.8 4.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TBPIP PF07106.8 ETS73661.1 - 0.32 10.5 5.8 0.36 10.3 2.9 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 ETS73661.1 - 0.49 10.2 14.2 0.14 12.0 7.5 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 ETS73661.1 - 0.51 9.9 4.5 0.98 8.9 3.1 1.4 1 0 0 1 1 1 0 IncA protein Complex1_LYR PF05347.10 ETS73662.1 - 1e-06 28.4 3.0 2.1e-06 27.4 2.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS73662.1 - 2.5e-05 24.3 2.2 5.4e-05 23.3 1.5 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 ETS73663.1 - 1.2e-14 54.1 0.1 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS73663.1 - 2.3e-07 30.4 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 ETS73663.1 - 3.1e-06 27.2 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS73663.1 - 0.00027 21.0 0.0 0.00036 20.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS73663.1 - 0.0024 18.0 0.2 0.003 17.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS73663.1 - 0.0065 16.4 0.0 0.019 14.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS73663.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F-box PF00646.28 ETS73666.1 - 0.069 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 F-box domain EDR1 PF14381.1 ETS73667.1 - 0.077 12.5 1.6 0.16 11.5 1.1 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 CHDCT2 PF08074.6 ETS73668.1 - 0.012 15.3 0.4 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain FAD_binding_3 PF01494.14 ETS73669.1 - 1.2e-15 57.4 6.6 7.4e-15 54.8 3.4 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS73669.1 - 3.7e-06 26.8 0.2 8.7e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS73669.1 - 6.4e-05 22.0 3.1 0.0012 17.8 0.9 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS73669.1 - 0.00016 21.4 1.4 0.00096 18.9 1.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS73669.1 - 0.00029 19.8 1.0 0.00029 19.8 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 ETS73669.1 - 0.00043 19.8 0.2 0.0012 18.4 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS73669.1 - 0.00057 20.0 0.2 0.0016 18.5 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS73669.1 - 0.0007 18.3 0.0 0.0069 15.0 0.0 2.0 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS73669.1 - 0.00079 19.3 0.3 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS73669.1 - 0.0014 19.0 1.2 0.0045 17.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS73669.1 - 0.02 13.3 0.9 0.038 12.4 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 ETS73669.1 - 0.055 12.3 0.5 0.083 11.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Flavi_NS5 PF00972.15 ETS73669.1 - 0.073 10.9 1.8 0.69 7.7 0.1 2.1 2 0 0 2 2 2 0 Flavivirus RNA-directed RNA polymerase KTSC PF13619.1 ETS73669.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 KTSC domain Lycopene_cycl PF05834.7 ETS73669.1 - 0.22 10.3 6.4 0.23 10.3 1.6 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein AMP-binding PF00501.23 ETS73670.1 - 1.1e-80 271.0 0.0 1.7e-78 263.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 ETS73670.1 - 4e-69 232.7 0.0 1.2e-40 139.2 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 ETS73670.1 - 1.4e-30 105.3 0.1 2.4e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.11 ETS73670.1 - 0.0011 18.6 0.1 0.043 13.3 0.0 2.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Laminin_I PF06008.9 ETS73670.1 - 0.012 14.9 0.2 0.056 12.7 0.0 2.0 2 0 0 2 2 2 0 Laminin Domain I HRDC PF00570.18 ETS73670.1 - 0.06 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 HRDC domain Myb_DNA-bind_3 PF12776.2 ETS73671.1 - 6.6e-18 65.1 0.2 1.1e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Asp PF00026.18 ETS73672.1 - 5.1e-69 232.9 7.9 6.2e-69 232.6 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 ETS73672.1 - 0.0054 17.2 4.8 0.12 12.8 1.2 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 ETS73672.1 - 0.0073 15.8 0.1 0.02 14.4 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 ETS73672.1 - 0.0095 15.9 0.1 0.045 13.7 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Glyco_hydro_97 PF10566.4 ETS73673.1 - 0.063 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 DUF4470 PF14737.1 ETS73674.1 - 4.1e-22 77.8 0.1 9.5e-22 76.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TehB PF03848.9 ETS73674.1 - 0.043 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Abhydrolase_5 PF12695.2 ETS73675.1 - 1.5e-16 60.4 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS73675.1 - 3.7e-07 30.2 0.8 0.0018 18.1 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS73675.1 - 0.001 18.3 0.1 0.18 10.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS73675.1 - 0.0017 17.9 0.0 0.0047 16.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 ETS73675.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF915 PF06028.6 ETS73675.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.6 ETS73675.1 - 0.035 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) FSH1 PF03959.8 ETS73675.1 - 0.11 11.9 0.0 0.4 10.0 0.0 1.8 1 1 1 2 2 2 0 Serine hydrolase (FSH1) MFS_1 PF07690.11 ETS73676.1 - 1.2e-31 109.7 41.8 4.2e-31 107.9 29.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 ETS73676.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3431 PF11913.3 ETS73679.1 - 5.2e-50 169.9 0.1 5.8e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) AIM24 PF01987.12 ETS73680.1 - 9.6e-49 165.7 0.0 1.2e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Acyl-CoA_dh_1 PF00441.19 ETS73681.1 - 2.3e-36 125.1 1.0 4.6e-36 124.1 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS73681.1 - 3.2e-13 48.9 1.5 6e-13 48.1 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS73681.1 - 6.1e-13 49.1 0.1 1.4e-12 48.0 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS73681.1 - 3.6e-08 33.9 0.0 8.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 ETS73681.1 - 0.0036 16.7 0.1 0.01 15.2 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.18 ETS73682.1 - 6.1e-41 140.7 0.0 1.8e-40 139.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS73682.1 - 1.5e-06 27.5 0.0 3.5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 ETS73682.1 - 0.0041 16.4 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 ETS73682.1 - 0.0046 15.6 0.0 0.021 13.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 ETS73682.1 - 0.022 13.7 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Kdo PF06293.9 ETS73682.1 - 0.13 11.3 0.0 0.84 8.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gpi1 PF05024.10 ETS73683.1 - 7.3e-65 218.1 8.5 1.3e-64 217.3 5.9 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3333 PF11812.3 ETS73683.1 - 0.055 13.4 0.3 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) DNA_pol_A_exo1 PF01612.15 ETS73685.1 - 1.4e-39 135.3 0.2 2.4e-39 134.6 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 ETS73685.1 - 3.5e-23 81.7 0.1 1e-22 80.2 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 ETS73685.1 - 1.3e-12 47.2 0.1 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain GCV_T PF01571.16 ETS73686.1 - 5.3e-36 123.9 0.0 7.4e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS73686.1 - 4e-10 39.5 0.0 1.3e-09 37.9 0.0 1.9 2 1 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain adh_short_C2 PF13561.1 ETS73687.1 - 8.9e-18 64.9 0.1 1.2e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS73687.1 - 7.2e-07 29.2 0.5 1.2e-06 28.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Bacteriocin_IId PF09221.5 ETS73687.1 - 1.3 8.9 6.1 13 5.8 2.2 2.2 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like adh_short PF00106.20 ETS73688.1 - 1.4e-14 54.3 0.3 1.5e-14 54.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73688.1 - 2.3e-08 33.8 0.2 2.8e-08 33.6 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73688.1 - 6.2e-07 29.4 0.1 7.1e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73688.1 - 1e-05 25.1 0.0 1.1e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS73688.1 - 0.00068 19.3 1.6 0.00093 18.9 0.9 1.5 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 ETS73688.1 - 0.00082 19.0 0.2 0.0011 18.5 0.2 1.1 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.1 ETS73688.1 - 0.00093 19.2 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS73688.1 - 0.011 14.3 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 ETS73688.1 - 0.016 15.0 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UPF0146 PF03686.8 ETS73688.1 - 0.031 14.0 0.1 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) THF_DHG_CYH_C PF02882.14 ETS73688.1 - 0.039 13.0 0.1 0.08 12.0 0.0 1.6 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 ETS73688.1 - 0.064 12.3 0.1 0.083 12.0 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thiolase_C PF02803.13 ETS73688.1 - 0.071 12.5 0.7 0.15 11.4 0.2 1.7 1 1 1 2 2 2 0 Thiolase, C-terminal domain Polysacc_synt_2 PF02719.10 ETS73688.1 - 0.091 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Thioesterase PF00975.15 ETS73689.1 - 4e-12 46.8 0.0 7e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 ETS73689.1 - 2.2e-06 27.7 0.3 4.3e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73689.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS73689.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETS73689.1 - 0.063 12.8 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 ETS73690.1 - 1.1e-29 103.8 0.2 1.3e-29 103.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS73690.1 - 8.4e-29 100.6 0.2 1.2e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73690.1 - 5.9e-16 58.6 0.1 8.1e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_6 PF08030.7 ETS73691.1 - 2.6e-31 108.6 0.0 4.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS73691.1 - 2.2e-20 72.4 0.0 6.1e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 ETS73691.1 - 1.1e-16 61.0 16.4 5.7e-16 58.7 7.5 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 ETS73691.1 - 0.027 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain UQ_con PF00179.21 ETS73692.1 - 1.5e-51 173.4 0.0 1.7e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS73692.1 - 6.5e-05 22.6 0.0 7.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS73692.1 - 0.0048 16.7 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETS73692.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain CVNH PF08881.5 ETS73693.1 - 2.5e-30 104.7 0.3 3.1e-30 104.4 0.2 1.1 1 0 0 1 1 1 1 CVNH domain p450 PF00067.17 ETS73694.1 - 1.2e-56 192.1 0.0 1.6e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 ETS73696.1 - 6e-22 77.3 22.6 5.1e-07 29.5 0.6 5.2 3 2 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETS73696.1 - 4.2e-17 61.4 31.3 0.02 14.8 0.5 9.0 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS73696.1 - 1.2e-15 57.5 17.5 0.25 11.6 0.2 7.9 1 1 6 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 ETS73696.1 - 4.7e-14 52.2 9.2 0.00025 21.1 0.1 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS73696.1 - 1.3e-09 38.4 32.4 0.0012 19.4 0.3 7.3 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETS73696.1 - 1.8e-09 36.8 10.9 1.9 8.6 0.1 7.9 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 ETS73696.1 - 5.6e-08 31.9 0.0 2.1e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 ETS73696.1 - 1.8e-06 28.0 29.8 0.74 10.6 0.3 8.9 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS73696.1 - 2e-06 27.8 8.4 9.9 6.8 0.0 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 ETS73696.1 - 4.8e-06 26.7 0.0 1.8e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 ETS73696.1 - 1.4e-05 25.1 0.1 8.6e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73696.1 - 1.5e-05 24.7 0.0 4.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_7 PF13176.1 ETS73696.1 - 3.1e-05 23.4 24.7 0.39 10.6 0.0 8.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS73696.1 - 3.3e-05 23.3 0.8 7.2 6.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PGAP1 PF07819.8 ETS73696.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS73696.1 - 0.0012 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_11 PF13414.1 ETS73696.1 - 0.0044 16.6 16.6 0.12 12.0 0.3 5.7 2 1 6 8 8 8 2 TPR repeat DUF900 PF05990.7 ETS73696.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 ETS73696.1 - 0.04 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0079 PF02367.12 ETS73696.1 - 0.079 12.5 4.8 1.5 8.4 0.1 3.4 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 SCFA_trans PF02667.9 ETS73696.1 - 0.1 11.3 0.1 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Short chain fatty acid transporter Cas_DxTHG PF09455.5 ETS73696.1 - 0.13 11.3 2.7 2.3 7.2 0.1 2.8 1 1 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family Paf67 PF10255.4 ETS73696.1 - 0.23 10.3 1.8 2.8 6.7 0.0 2.9 1 1 3 4 4 4 0 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.9 ETS73696.1 - 2.1 8.9 26.5 0.43 11.1 0.3 6.2 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS73696.1 - 9 6.4 31.1 4 7.6 0.1 8.1 4 1 6 10 10 9 0 Tetratricopeptide repeat DUF3883 PF13020.1 ETS73697.1 - 1.2e-05 24.9 0.1 3.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) GST_N PF02798.15 ETS73700.1 - 4.6e-10 39.5 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS73700.1 - 1.3e-09 37.9 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS73700.1 - 2.7e-09 37.3 0.1 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS73700.1 - 2.2e-08 34.1 0.0 4.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS73700.1 - 2.7e-08 33.6 0.0 5.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS73700.1 - 1.6e-06 27.8 0.1 3.3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pectate_lyase_3 PF12708.2 ETS73701.1 - 6.6e-59 199.7 25.3 2.7e-53 181.3 5.0 3.5 3 1 0 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 ETS73701.1 - 9.8e-16 57.7 0.1 9.8e-16 57.7 0.0 2.3 2 0 0 2 2 2 1 Subtilase family HMG_CoA_synt_N PF01154.12 ETS73705.1 - 2.3e-81 271.4 0.0 2.7e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 ETS73705.1 - 2e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF697 PF05128.7 ETS73705.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF2235 PF09994.4 ETS73706.1 - 3.1e-65 220.3 0.0 7.2e-65 219.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1682 PF07946.9 ETS73706.1 - 3.1 6.5 10.3 0.042 12.6 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) adh_short PF00106.20 ETS73707.1 - 1.2e-12 48.0 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73707.1 - 6.6e-06 26.0 0.0 1.9e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73707.1 - 5.7e-05 22.8 0.0 9.2e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 KR domain TIR-like PF10137.4 ETS73707.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Zn_clus PF00172.13 ETS73708.1 - 0.003 17.4 9.9 0.0066 16.3 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_10 PF13374.1 ETS73709.1 - 1.1e-66 219.0 7.2 1.9e-09 37.1 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETS73709.1 - 2.6e-58 193.9 5.2 9.5e-17 60.7 0.6 6.7 4 1 4 8 8 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS73709.1 - 1.3e-16 60.7 4.5 3.1e-05 24.5 0.2 6.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS73709.1 - 3.2e-16 57.7 13.5 0.0067 16.1 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETS73709.1 - 1.1e-15 56.4 12.4 0.019 14.5 0.4 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 ETS73709.1 - 9.2e-14 50.4 11.4 0.24 11.9 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS73709.1 - 1.2e-13 50.4 7.7 1.1e-05 25.0 0.5 5.1 3 2 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETS73709.1 - 1.4e-12 46.5 20.2 0.044 13.7 0.3 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS73709.1 - 3.3e-11 42.4 4.3 0.62 10.4 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.7 ETS73709.1 - 8e-09 35.3 0.0 1.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Apc3 PF12895.2 ETS73709.1 - 4.9e-08 32.9 0.1 0.04 14.0 0.0 4.3 1 1 5 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 FTCD PF02971.9 ETS73709.1 - 1.2e-07 31.4 0.8 4.2 7.0 0.0 5.0 1 1 4 5 5 5 2 Formiminotransferase domain TPR_14 PF13428.1 ETS73709.1 - 1.6e-07 31.2 23.3 0.6 10.8 0.5 8.6 5 3 4 9 9 8 3 Tetratricopeptide repeat AAA_25 PF13481.1 ETS73709.1 - 1.9e-07 30.7 0.0 1.1e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETS73709.1 - 5e-07 28.8 0.0 7.5e-06 25.0 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 ETS73709.1 - 9.3e-07 29.1 14.3 0.1 12.9 1.1 5.9 4 1 3 7 7 6 3 Tetratricopeptide repeat AAA_22 PF13401.1 ETS73709.1 - 0.0002 21.5 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS73709.1 - 0.00026 21.0 0.0 0.00026 21.0 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain TPR_8 PF13181.1 ETS73709.1 - 0.00072 19.1 10.6 1.3 8.9 0.1 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Rab5-bind PF09311.6 ETS73709.1 - 0.0058 16.5 6.7 0.37 10.6 1.1 3.0 2 1 0 2 2 2 2 Rabaptin-like protein TPR_6 PF13174.1 ETS73709.1 - 0.029 14.8 7.6 1.7e+02 3.0 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3366 PF11846.3 ETS73709.1 - 0.076 12.8 6.3 24 4.7 0.0 5.6 2 1 2 5 5 5 0 Domain of unknown function (DUF3366) MIT PF04212.13 ETS73709.1 - 1.3 8.9 4.7 0.67 9.8 0.3 2.9 2 1 1 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETS73709.1 - 2.7 7.8 9.1 7.9 6.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GST_N PF02798.15 ETS73710.1 - 4.5e-13 49.1 0.0 1.4e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS73710.1 - 3.5e-11 43.1 0.0 6.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS73710.1 - 4.6e-11 42.4 0.0 8.3e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS73710.1 - 1e-10 41.4 0.0 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS73710.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS73710.1 - 1.7e-06 28.4 0.1 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 ETS73711.1 - 3.3e-08 33.2 0.1 1.5e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS73711.1 - 0.00023 20.1 0.1 0.00051 19.0 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 ETS73711.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS73711.1 - 0.03 14.3 0.1 0.087 12.8 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 ETS73711.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1846 PF08903.6 ETS73712.1 - 0.067 11.6 0.3 0.099 11.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Sulfatase PF00884.18 ETS73713.1 - 7.9e-62 209.1 0.0 1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS73713.1 - 3e-06 26.7 0.6 0.0039 16.5 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 ETS73713.1 - 0.00044 18.7 0.5 0.0009 17.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sugar_tr PF00083.19 ETS73714.1 - 1.4e-75 254.6 27.6 1.6e-75 254.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73714.1 - 6.1e-13 48.2 45.0 6e-09 35.0 14.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS73714.1 - 6.2e-05 21.5 7.1 6.2e-05 21.5 4.9 3.2 3 1 1 4 4 4 2 MFS/sugar transport protein Metallophos PF00149.23 ETS73715.1 - 0.0042 16.5 3.4 0.0095 15.3 2.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_49 PF03718.8 ETS73716.1 - 1.3e-174 581.4 0.1 1.7e-174 581.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 HET PF06985.6 ETS73717.1 - 1.5e-26 93.2 0.0 6.2e-26 91.2 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABM PF03992.11 ETS73718.1 - 2.8e-05 24.0 0.0 3.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.13 ETS73719.1 - 5e-08 32.1 0.1 1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73719.1 - 5.4e-06 26.2 7.8 1.1e-05 25.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_red_lgN PF00317.16 ETS73719.1 - 0.088 12.6 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain FAD_binding_3 PF01494.14 ETS73720.1 - 4.2e-17 62.2 0.1 2.6e-11 43.1 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS73720.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS73720.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS73720.1 - 0.074 13.4 0.0 0.35 11.2 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS73720.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 ETS73721.1 - 6e-20 71.4 0.0 1.2e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS73721.1 - 4.1e-16 59.5 0.0 6.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS73721.1 - 1.1e-08 34.8 0.0 1.7e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS73721.1 - 2.7e-05 23.2 0.1 4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 ETS73721.1 - 0.0007 19.5 0.1 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 ETS73721.1 - 0.0026 17.6 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 ETS73721.1 - 0.0033 17.3 0.1 0.0077 16.1 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 ETS73721.1 - 0.0052 16.4 0.1 0.016 14.8 0.0 1.7 1 1 1 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.14 ETS73721.1 - 0.066 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS73721.1 - 0.076 11.7 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_4 PF13439.1 ETS73721.1 - 0.093 12.4 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 CbiJ PF02571.9 ETS73721.1 - 0.14 11.4 0.1 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK DNA_repr_REX1B PF14966.1 ETS73722.1 - 0.094 13.0 2.8 0.11 12.9 0.7 2.1 2 0 0 2 2 2 0 DNA repair REX1-B ALMT PF11744.3 ETS73722.1 - 0.3 9.6 6.1 0.64 8.6 4.2 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.5 ETS73722.1 - 3.5 7.7 12.3 0.9 9.6 0.1 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 ETS73722.1 - 3.6 6.6 11.8 2.9 6.9 5.7 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4038 PF13204.1 ETS73723.1 - 8.2e-48 163.1 0.3 2.4e-46 158.3 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.2 ETS73723.1 - 3.5e-07 29.9 0.3 9e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Putative collagen-binding domain of a collagenase YL1_C PF08265.6 ETS73723.1 - 0.083 12.4 0.0 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Aldo_ket_red PF00248.16 ETS73724.1 - 3.8e-54 183.4 0.0 4.3e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.16 ETS73725.1 - 7.5e-07 28.6 5.5 1.3e-06 27.8 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_M4 PF01447.13 ETS73725.1 - 0.017 15.2 0.6 0.045 13.8 0.5 1.6 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain p450 PF00067.17 ETS73726.1 - 1.5e-51 175.3 0.0 3.9e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 IncA PF04156.9 ETS73727.1 - 3.5e-08 33.2 158.5 0.034 13.7 10.4 8.2 1 1 6 7 7 6 5 IncA protein DUF3584 PF12128.3 ETS73727.1 - 8.4e-07 26.7 58.5 8.4e-07 26.7 40.6 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 ETS73727.1 - 1.3e-06 28.3 160.9 0.0082 16.0 10.5 8.7 1 1 9 10 10 10 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 ETS73727.1 - 8e-06 25.2 83.2 0.0012 18.0 9.4 5.5 1 1 4 5 5 5 3 Reovirus sigma C capsid protein WEMBL PF05701.6 ETS73727.1 - 1.7e-05 23.5 187.8 0.00029 19.4 57.4 4.1 1 1 3 4 4 4 3 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 ETS73727.1 - 1.8e-05 22.7 156.1 2.1e-05 22.4 52.2 3.8 1 1 3 4 4 4 4 Myosin tail Filament PF00038.16 ETS73727.1 - 2e-05 24.2 128.5 0.34 10.3 32.3 6.9 1 1 3 4 4 4 3 Intermediate filament protein GAS PF13851.1 ETS73727.1 - 0.00012 21.3 139.6 0.29 10.2 14.2 7.5 1 1 7 8 8 8 5 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 ETS73727.1 - 0.00034 20.4 70.4 0.00075 19.3 22.5 7.9 1 1 7 8 8 6 2 Tropomyosin like DUF4201 PF13870.1 ETS73727.1 - 0.0028 17.1 117.8 0.2 11.0 5.0 9.2 2 2 6 8 8 8 5 Domain of unknown function (DUF4201) Spc7 PF08317.6 ETS73727.1 - 0.0047 15.6 26.4 0.0047 15.6 18.3 6.3 1 1 5 6 6 6 4 Spc7 kinetochore protein AAA_27 PF13514.1 ETS73727.1 - 0.0082 13.9 148.0 0.15 9.6 26.6 3.1 1 1 2 3 3 3 3 AAA domain Spectrin PF00435.16 ETS73727.1 - 0.011 15.9 8.3 0.011 15.9 5.7 9.6 2 2 8 10 10 7 0 Spectrin repeat HOOK PF05622.7 ETS73727.1 - 0.032 12.0 122.4 0.029 12.1 0.8 4.9 1 1 2 4 4 4 0 HOOK protein ERM PF00769.14 ETS73727.1 - 0.056 12.9 163.9 0.28 10.6 19.0 6.1 1 1 4 5 5 5 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 ETS73727.1 - 0.11 10.9 132.6 0.1 11.0 25.0 5.3 1 1 4 5 5 5 0 AAA domain MscS_porin PF12795.2 ETS73727.1 - 0.11 11.7 152.3 0.25 10.6 19.3 7.8 1 1 5 7 7 7 0 Mechanosensitive ion channel porin domain CALCOCO1 PF07888.6 ETS73727.1 - 0.15 10.3 121.8 0.2 9.9 19.1 3.8 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like Snapin_Pallidin PF14712.1 ETS73727.1 - 0.94 9.8 94.0 0.35 11.1 4.6 10.6 2 2 9 11 11 10 0 Snapin/Pallidin ATG16 PF08614.6 ETS73727.1 - 1.3 8.8 142.4 0.28 10.9 3.0 7.3 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 ETS73727.1 - 5.9 6.7 80.1 1 9.1 1.6 8.7 2 2 5 9 9 9 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 ETS73727.1 - 9.8 6.2 85.4 2.2 8.3 4.5 7.6 1 1 4 7 7 7 0 Fibrinogen alpha/beta chain family p450 PF00067.17 ETS73728.1 - 3.2e-42 144.6 0.0 4.1e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 ETS73730.1 - 1.1e-95 320.3 0.0 1.3e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETS73730.1 - 0.024 13.5 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II HAD_2 PF13419.1 ETS73731.1 - 3.4e-25 89.2 0.1 4.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS73731.1 - 0.00035 21.0 0.0 0.00076 19.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAO PF01266.19 ETS73732.1 - 3.5e-51 174.2 1.2 4.1e-51 173.9 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS73732.1 - 4.7e-09 36.6 0.5 6.9e-07 29.5 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS73732.1 - 5.9e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS73732.1 - 0.00038 19.6 0.0 0.00085 18.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 ETS73732.1 - 0.0004 19.3 2.3 0.0019 17.1 1.6 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS73732.1 - 0.00042 20.1 0.1 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS73732.1 - 0.0034 17.2 0.1 0.0092 15.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS73732.1 - 0.0047 15.9 0.2 0.028 13.3 0.0 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 ETS73732.1 - 0.0076 15.3 1.2 0.14 11.1 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS73732.1 - 0.028 12.9 0.2 1.6 7.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 ETS73732.1 - 0.056 13.8 1.8 9.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS73732.1 - 0.08 11.9 0.2 8.6 5.3 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain CBS PF00571.23 ETS73733.1 - 4.1e-42 141.7 11.2 4.3e-11 42.4 0.0 6.3 7 0 0 7 7 7 4 CBS domain PB1 PF00564.19 ETS73733.1 - 6.4e-09 35.3 0.1 1.8e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Myc_N PF01056.13 ETS73733.1 - 0.04 13.0 0.2 0.04 13.0 0.1 2.2 3 0 0 3 3 3 0 Myc amino-terminal region Tyrosinase PF00264.15 ETS73734.1 - 5.1e-26 92.2 5.8 1.7e-12 48.0 2.1 2.1 1 1 1 2 2 2 2 Common central domain of tyrosinase Tyrosinase PF00264.15 ETS73735.1 - 8.2e-19 68.6 4.0 1.5e-18 67.7 2.8 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.23 ETS73736.1 - 2.9e-05 23.5 3.0 0.001 18.4 2.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS73736.1 - 0.00025 20.9 0.0 0.00065 19.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldo_ket_red PF00248.16 ETS73737.1 - 8.5e-50 169.1 0.0 1.1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_C PF00137.16 ETS73739.1 - 1.1e-15 57.3 9.5 1.1e-15 57.3 6.6 1.9 2 1 1 3 3 3 1 ATP synthase subunit C WPP PF13943.1 ETS73739.1 - 0.27 11.4 3.0 0.4 10.9 2.1 1.3 1 0 0 1 1 1 0 WPP domain SpoIID PF08486.5 ETS73739.1 - 2 8.7 6.7 2.7 8.3 4.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein MOZ_SAS PF01853.13 ETS73741.1 - 3.2e-52 176.5 0.0 6e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Chordopox_E11 PF06138.7 ETS73742.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus E11 protein HET PF06985.6 ETS73743.1 - 1.6e-22 80.1 1.2 7.6e-19 68.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 ETS73744.1 - 1.2e-89 300.9 0.0 1.8e-89 300.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS73744.1 - 4.1e-48 163.1 0.0 9.6e-48 161.9 0.0 1.6 2 0 0 2 2 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 ETS73744.1 - 2.5e-06 26.7 0.1 0.00086 18.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 ETS73744.1 - 4e-05 22.6 0.1 0.00023 20.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS73744.1 - 0.00029 19.8 0.0 0.00049 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS73744.1 - 0.00033 20.6 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS73744.1 - 0.00033 20.6 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS73744.1 - 0.00046 18.7 0.0 0.00076 18.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS73744.1 - 0.00068 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 ETS73744.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS73744.1 - 0.0032 16.3 0.1 0.008 15.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS73744.1 - 0.025 13.6 0.1 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS73744.1 - 0.036 14.1 0.1 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS73744.1 - 0.038 12.8 0.0 0.77 8.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase XdhC_C PF13478.1 ETS73744.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_9 PF13454.1 ETS73744.1 - 0.11 12.2 0.2 1.3 8.7 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding DUF3218 PF11508.3 ETS73744.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Clp1 PF06807.9 ETS73745.1 - 2.4e-11 43.7 0.0 9.6e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETS73745.1 - 0.00026 20.6 0.0 0.00082 19.0 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETS73745.1 - 0.017 15.8 0.0 0.04 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 ETS73745.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 MutS domain V AAA_14 PF13173.1 ETS73745.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.6 ETS73746.1 - 4e-19 69.0 27.8 4e-19 69.0 19.3 4.9 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Zn_clus PF00172.13 ETS73747.1 - 0.099 12.5 14.5 0.19 11.6 10.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.16 ETS73748.1 - 1.8e-08 34.0 15.6 1.8e-08 34.0 10.8 2.4 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 ETS73748.1 - 5.6e-06 26.0 5.5 5.6e-06 26.0 3.8 2.1 3 0 0 3 3 3 1 PAP2 superfamily DUF1056 PF06341.6 ETS73748.1 - 1.7 8.7 6.1 0.5 10.4 1.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1056) NACHT PF05729.7 ETS73749.1 - 1e-15 57.7 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 ETS73749.1 - 4.1e-08 32.7 4.9 7.4e-05 22.4 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETS73749.1 - 1.7e-05 23.8 0.0 5.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region RNA_helicase PF00910.17 ETS73749.1 - 0.025 14.7 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4642 PF15484.1 ETS73749.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) AAA_19 PF13245.1 ETS73749.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Muted PF14942.1 ETS73749.1 - 0.69 9.7 5.3 9.1 6.1 0.9 3.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.20 ETS73750.1 - 3.3e-69 232.9 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS73750.1 - 4.2e-30 104.6 0.0 5.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS73750.1 - 5.5e-06 25.5 0.0 9.8e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS73750.1 - 0.00062 19.5 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS73750.1 - 0.0023 17.0 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS73750.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ank_2 PF12796.2 ETS73751.1 - 6.3e-246 795.6 79.1 8.3e-20 70.9 1.0 16.5 4 3 13 20 20 20 20 Ankyrin repeats (3 copies) Ank PF00023.25 ETS73751.1 - 1.6e-175 560.9 86.1 1.3e-08 34.2 0.1 35.5 35 0 0 35 35 35 31 Ankyrin repeat Ank_4 PF13637.1 ETS73751.1 - 1.5e-137 445.8 45.6 9.8e-11 41.8 0.1 24.3 13 6 14 27 27 27 26 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73751.1 - 2.1e-125 395.8 48.8 9.1e-05 22.3 0.0 34.2 34 1 1 35 35 35 28 Ankyrin repeat Ank_5 PF13857.1 ETS73751.1 - 4.5e-121 392.1 67.3 8.2e-11 41.7 0.0 28.8 7 5 24 31 31 31 26 Ankyrin repeats (many copies) NACHT PF05729.7 ETS73751.1 - 3.3e-09 36.6 0.0 1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS73751.1 - 9.5e-08 32.2 0.5 5.8e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS73751.1 - 0.00018 21.6 0.0 0.00084 19.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain PH_8 PF15409.1 ETS73751.1 - 0.11 12.5 0.1 23 5.1 0.0 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain RF-1 PF00472.15 ETS73752.1 - 8.8e-13 48.0 0.2 1.2e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2059 PF09832.4 ETS73752.1 - 0.052 13.5 1.0 0.27 11.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF2913 PF11140.3 ETS73752.1 - 0.054 12.7 0.6 0.1 11.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) RRM_1 PF00076.17 ETS73753.1 - 1.2e-10 40.8 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS73753.1 - 1.1e-06 28.4 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS73753.1 - 2.2e-05 24.2 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 ETS73754.1 - 2.1e-65 221.0 0.0 3.4e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 ETS73757.1 - 7.5e-21 74.5 0.1 4.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS73757.1 - 0.0017 18.3 0.0 0.0056 16.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS73757.1 - 0.0028 16.5 0.1 0.009 14.9 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS73757.1 - 0.0084 16.4 0.3 1.6 9.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS73757.1 - 0.031 13.1 0.3 0.056 12.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS73757.1 - 0.039 13.6 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 ETS73757.1 - 0.047 13.5 0.2 0.17 11.7 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2089 PF09862.4 ETS73757.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Lycopene_cycl PF05834.7 ETS73757.1 - 0.16 10.8 0.8 2.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein LETM1 PF07766.8 ETS73759.1 - 3.6e-09 36.0 0.1 3.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein Ribonuc_L-PSP PF01042.16 ETS73760.1 - 6e-30 103.4 0.1 6.8e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dynamin_N PF00350.18 ETS73761.1 - 5.7e-29 101.0 0.0 1.3e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS73761.1 - 1.8e-19 69.6 0.0 2.1e-17 62.8 0.1 2.7 2 1 0 2 2 2 1 Dynamin central region GED PF02212.13 ETS73761.1 - 1.9e-05 24.4 1.5 0.0011 18.8 0.0 3.5 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS73761.1 - 0.0087 16.0 0.0 0.037 13.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS73761.1 - 0.023 15.1 0.0 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 ETS73761.1 - 0.028 13.9 0.1 0.3 10.5 0.0 2.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family HR1 PF02185.11 ETS73761.1 - 0.039 13.6 0.3 1.9 8.3 0.1 2.9 2 0 0 2 2 2 0 Hr1 repeat AAA_21 PF13304.1 ETS73761.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain XFP_N PF09364.5 ETS73762.1 - 1.8e-177 589.6 0.0 2.3e-177 589.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 ETS73762.1 - 1.3e-81 272.9 0.0 1.8e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 ETS73762.1 - 3.7e-80 267.7 0.0 9.2e-80 266.4 0.0 1.7 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase E1_dh PF00676.15 ETS73762.1 - 0.19 10.4 0.0 0.47 9.1 0.0 1.6 1 0 0 1 1 1 0 Dehydrogenase E1 component p450 PF00067.17 ETS73763.1 - 1.5e-43 149.0 0.0 1.8e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS73765.1 - 3.8e-52 177.3 0.0 5.7e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3254 PF11630.3 ETS73766.1 - 0.043 13.7 0.1 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) Methyltransf_2 PF00891.13 ETS73767.1 - 4.2e-34 117.8 0.0 5e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS73767.1 - 2e-05 25.1 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73767.1 - 0.00062 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS73767.1 - 0.0044 16.7 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS73767.1 - 0.0048 16.5 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain BCL_N PF04714.8 ETS73767.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 BCL7, N-terminal conserver region CheR PF01739.13 ETS73767.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Fungal_trans PF04082.13 ETS73768.1 - 1.1e-06 27.7 0.7 2e-06 26.8 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73768.1 - 3.1e-05 23.7 8.9 4.9e-05 23.1 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 ETS73769.1 - 3.9e-10 40.1 0.0 8.5e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_4 PF01565.18 ETS73771.1 - 3.5e-26 91.3 1.5 6.6e-26 90.4 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS73771.1 - 0.00016 21.4 0.3 0.00039 20.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.4 ETS73772.1 - 2.1e-26 92.8 1.7 2.8e-26 92.4 1.2 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS73772.1 - 0.00039 19.8 0.1 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Glyco_hydro_35 PF01301.14 ETS73773.1 - 1.2e-76 258.0 0.4 1.9e-76 257.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS73773.1 - 1.4e-58 197.2 0.4 2.1e-58 196.6 0.3 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS73773.1 - 3.1e-49 165.8 8.9 2.2e-25 89.1 1.1 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS73773.1 - 6.5e-19 67.1 0.0 1.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Transferase PF02458.10 ETS73774.1 - 4.2e-13 48.5 0.0 9.8e-12 44.0 0.0 2.6 2 1 0 2 2 2 1 Transferase family Condensation PF00668.15 ETS73774.1 - 0.028 13.2 0.0 0.062 12.1 0.0 1.5 2 0 0 2 2 2 0 Condensation domain DUF346 PF03984.8 ETS73775.1 - 0.0082 15.5 1.3 0.0082 15.5 0.9 5.8 6 1 0 6 6 6 3 Repeat of unknown function (DUF346) DUF551 PF04448.7 ETS73775.1 - 0.044 14.5 1.0 3.8 8.3 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF551) VCBS PF13517.1 ETS73775.1 - 6.3 7.2 12.3 26 5.2 2.8 3.8 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAM33 PF02330.11 ETS73776.1 - 6.9e-33 114.1 3.5 8.3e-33 113.8 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein XPG_I PF00867.13 ETS73777.1 - 2.2e-24 85.3 0.0 4.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ETS73777.1 - 5.6e-21 74.7 0.0 1.2e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 ETS73777.1 - 0.00074 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing HTH_24 PF13412.1 ETS73777.1 - 0.065 12.6 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding 5_3_exonuc PF01367.15 ETS73777.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF2962 PF11176.3 ETS73778.1 - 1.1e-42 145.1 1.7 1.3e-42 145.0 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) ATP-synt_ab_C PF00306.22 ETS73778.1 - 0.027 14.9 0.1 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HTH_32 PF13565.1 ETS73778.1 - 0.085 13.6 7.2 0.86 10.4 0.1 2.5 1 1 1 2 2 2 0 Homeodomain-like domain IBR PF01485.16 ETS73779.1 - 1e-23 82.9 44.2 1.3e-11 44.2 3.4 4.5 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 ETS73779.1 - 7.2e-09 35.3 36.1 4.5e-06 26.4 2.9 3.6 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4 PF00097.20 ETS73779.1 - 8.9e-08 31.6 39.3 3.2e-05 23.4 3.2 4.4 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS73779.1 - 2.1e-05 24.4 7.0 2.1e-05 24.4 4.9 4.6 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS73779.1 - 0.0035 17.0 7.7 0.0035 17.0 5.3 3.9 2 1 1 3 3 3 1 zinc-RING finger domain UN_NPL4 PF11543.3 ETS73779.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.1 ETS73779.1 - 0.032 14.1 33.4 0.11 12.4 2.0 4.6 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS73779.1 - 0.18 11.5 20.8 0.043 13.5 1.6 3.8 3 0 0 3 3 3 0 RING-type zinc-finger MFS_1 PF07690.11 ETS73780.1 - 1.7e-34 119.1 53.8 1.7e-34 119.1 37.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS73780.1 - 0.17 11.6 5.9 0.035 13.8 0.9 2.3 2 0 0 2 2 2 0 MFS_1 like family Zn_clus PF00172.13 ETS73781.1 - 4.2e-05 23.3 8.5 0.0001 22.1 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73781.1 - 9.3e-05 21.4 0.1 9.3e-05 21.4 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain IncA PF04156.9 ETS73781.1 - 0.19 11.3 1.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 IncA protein Redoxin PF08534.5 ETS73782.1 - 1.4e-25 89.5 0.0 1.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS73782.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glyco_hydro_61 PF03443.9 ETS73783.1 - 5.9e-23 81.8 0.0 7.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 ETS73784.1 - 4e-25 88.2 30.2 4e-25 88.2 20.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MAPEG PF01124.13 ETS73785.1 - 6.4e-17 61.3 1.3 7.4e-17 61.1 0.9 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 ETS73785.1 - 0.36 10.5 3.9 0.26 11.0 1.5 1.6 1 1 0 1 1 1 0 Bacterial Transmembrane Pair family DUF167 PF02594.11 ETS73786.1 - 3.9e-19 68.3 0.5 6.2e-19 67.7 0.2 1.4 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 DUF3115 PF11312.3 ETS73788.1 - 2.6e-63 213.7 0.0 3.3e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Arc PF03869.9 ETS73789.1 - 0.017 14.7 0.9 4 7.1 0.1 2.2 2 0 0 2 2 2 0 Arc-like DNA binding domain DUF4111 PF13427.1 ETS73789.1 - 0.039 13.7 0.5 4.4 7.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) VirionAssem_T7 PF11653.3 ETS73789.1 - 0.084 13.6 1.1 2.3 9.0 0.1 2.1 1 1 1 2 2 2 0 Bacteriophage T7 virion assembly protein DUF413 PF04219.7 ETS73789.1 - 0.1 12.3 1.0 0.36 10.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF DUF2389 PF09493.5 ETS73789.1 - 0.92 9.8 7.0 0.76 10.0 0.7 2.2 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) DUF1059 PF06348.6 ETS73789.1 - 7.1 6.5 6.0 18 5.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Glyco_hydro_47 PF01532.15 ETS73791.1 - 4.9e-160 533.0 0.0 6.3e-160 532.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ADH_N PF08240.7 ETS73792.1 - 1.3e-26 92.5 4.8 2.1e-26 91.8 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73792.1 - 5.4e-17 61.5 0.0 4.3e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS73792.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS73792.1 - 0.012 15.2 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 ETS73792.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETS73792.1 - 0.26 11.1 2.0 0.6 9.9 0.8 2.0 2 0 0 2 2 2 0 ThiF family Adaptin_N PF01602.15 ETS73794.1 - 1.6e-145 485.4 3.7 2.3e-145 484.9 2.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETS73794.1 - 3.8e-25 88.7 1.2 2.5e-24 86.0 0.0 2.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS73794.1 - 4e-16 59.0 0.5 1.8e-06 28.0 0.0 5.0 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 ETS73794.1 - 4.1e-11 41.9 3.5 0.016 15.2 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 ETS73794.1 - 8.6e-06 26.0 0.5 1.9 9.0 0.0 5.8 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 ETS73794.1 - 0.0024 17.6 0.3 7.4 6.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 ETS73794.1 - 0.006 16.2 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.3 ETS73794.1 - 0.0096 15.5 0.8 0.18 11.4 0.1 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 ETS73794.1 - 0.018 14.3 0.2 2.2 7.5 0.0 3.2 3 1 1 4 4 4 0 CLASP N terminal DUF1548 PF07579.6 ETS73794.1 - 0.099 12.7 0.1 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DIOX_N PF14226.1 ETS73796.1 - 5e-28 97.9 0.0 8.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS73796.1 - 2e-18 66.4 0.0 4.6e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS73797.1 - 4.2e-30 104.6 21.4 4.2e-30 104.6 14.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PAS_9 PF13426.1 ETS73798.1 - 5.4e-20 71.6 0.0 1.5e-11 44.5 0.0 3.4 3 0 0 3 3 3 2 PAS domain GATA PF00320.22 ETS73798.1 - 7.7e-15 53.9 7.6 1.6e-14 52.9 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 ETS73798.1 - 8.2e-11 41.8 0.0 2.8e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 ETS73798.1 - 1.1e-05 25.3 0.2 0.0063 16.4 0.0 4.0 3 1 0 3 3 3 1 PAS domain PAS PF00989.19 ETS73798.1 - 2.2e-05 24.2 0.0 0.018 14.8 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 ETS73798.1 - 0.00033 20.6 0.0 0.17 11.9 0.0 3.2 3 0 0 3 3 3 1 PAS fold DIOX_N PF14226.1 ETS73799.1 - 4.7e-25 88.3 0.0 7.4e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS73799.1 - 3.2e-22 78.6 0.0 5.9e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SnoaL_4 PF13577.1 ETS73800.1 - 1.5e-10 41.0 0.7 1.9e-10 40.7 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS73800.1 - 0.047 13.9 1.2 0.075 13.2 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Scytalone_dh PF02982.9 ETS73800.1 - 0.055 13.0 0.2 0.076 12.5 0.1 1.5 1 1 0 1 1 1 0 Scytalone dehydratase MFS_1 PF07690.11 ETS73801.1 - 5.7e-17 61.4 42.6 5.7e-17 61.4 29.5 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS73801.1 - 3e-05 22.7 7.1 3e-05 22.7 4.9 3.5 1 1 2 3 3 3 2 Sugar (and other) transporter DUF4463 PF14703.1 ETS73802.1 - 0.066 13.7 0.2 1.7 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF1102 PF06510.6 ETS73802.1 - 0.18 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Tautomerase_3 PF14832.1 ETS73806.1 - 3.4e-14 53.0 0.1 4e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 ETS73806.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme BolA PF01722.13 ETS73807.1 - 1.9e-21 75.8 0.0 2.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 ETS73808.1 - 1.7e-54 184.9 0.0 2e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4197 PF13852.1 ETS73808.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Vps51 PF08700.6 ETS73809.1 - 2.9e-29 100.7 0.7 4.6e-29 100.0 0.1 1.7 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 ETS73809.1 - 0.00032 19.2 1.1 0.00043 18.8 0.8 1.1 1 0 0 1 1 1 1 Dor1-like family BBP1_C PF15272.1 ETS73809.1 - 0.025 14.1 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal COG5 PF10392.4 ETS73809.1 - 0.033 14.1 0.3 0.062 13.2 0.2 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Prominin PF05478.6 ETS73809.1 - 0.085 10.3 0.2 0.12 9.8 0.1 1.2 1 0 0 1 1 1 0 Prominin DUF1767 PF08585.7 ETS73810.1 - 5.2e-07 29.8 0.0 7.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) COG5 PF10392.4 ETS73811.1 - 8.3e-39 132.5 2.0 8.3e-39 132.5 1.4 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Dor1 PF04124.7 ETS73811.1 - 0.021 13.2 0.4 0.041 12.3 0.3 1.5 1 0 0 1 1 1 0 Dor1-like family SPX PF03105.14 ETS73811.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 SPX domain DUF1192 PF06698.6 ETS73812.1 - 0.022 14.5 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Epiglycanin_C PF14654.1 ETS73813.1 - 0.00084 19.3 1.1 0.0015 18.5 0.1 1.9 2 0 0 2 2 2 1 Mucin, catalytic, TM and cytoplasmic tail region Rifin_STEVOR PF02009.11 ETS73813.1 - 0.0014 18.2 0.1 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 ETS73813.1 - 0.005 16.3 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ODV-E18 PF10717.4 ETS73813.1 - 0.024 14.0 0.1 0.068 12.6 0.0 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TMEM154 PF15102.1 ETS73813.1 - 8 6.1 15.3 6.4e+02 -0.1 10.6 2.4 1 1 0 1 1 1 0 TMEM154 protein family Sulfotransfer_3 PF13469.1 ETS73814.1 - 0.11 13.4 0.9 0.2 12.5 0.6 1.6 1 1 0 1 1 1 0 Sulfotransferase family Methyltransf_23 PF13489.1 ETS73815.1 - 5.8e-11 42.3 0.0 9.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73815.1 - 4.2e-06 27.1 0.0 9.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73815.1 - 2.2e-05 25.0 0.0 8.5e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS73815.1 - 0.0009 19.6 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS73815.1 - 0.0029 16.6 0.0 0.008 15.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 ETS73815.1 - 0.0057 16.1 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 ETS73815.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CFEM PF05730.6 ETS73816.1 - 2e-12 46.7 10.5 3.4e-12 46.0 7.3 1.4 1 0 0 1 1 1 1 CFEM domain Nitroreductase PF00881.19 ETS73816.1 - 0.095 12.5 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Nitroreductase family Gamma-thionin PF00304.15 ETS73816.1 - 0.23 11.5 4.0 0.88 9.6 0.4 2.2 2 0 0 2 2 2 0 Gamma-thionin family HCV_NS5a_1a PF08300.8 ETS73817.1 - 0.53 10.2 5.9 0.6 10.0 4.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain FMN_dh PF01070.13 ETS73818.1 - 7.5e-101 337.5 0.1 3.8e-73 246.3 0.0 2.2 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS73818.1 - 1.1e-21 76.3 0.0 2.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS73818.1 - 2.4e-08 33.3 0.1 4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 ETS73818.1 - 3.1e-05 23.3 0.4 0.061 12.5 0.0 2.8 3 0 0 3 3 3 2 Histidine biosynthesis protein IMPDH PF00478.20 ETS73818.1 - 7.3e-05 21.8 4.3 0.00039 19.4 1.9 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ETS73818.1 - 0.0022 17.1 0.3 0.52 9.3 0.0 2.9 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 ETS73818.1 - 0.0092 14.8 0.3 0.078 11.7 0.0 2.1 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 ETS73818.1 - 0.02 13.8 0.1 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 ETS73818.1 - 0.025 13.7 0.1 0.051 12.7 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase DUF561 PF04481.7 ETS73818.1 - 0.19 10.6 0.2 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Fungal_trans PF04082.13 ETS73819.1 - 7.3e-07 28.3 0.1 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73819.1 - 5e-05 23.1 12.5 9.1e-05 22.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_EGF PF00053.19 ETS73819.1 - 0.1 12.5 10.1 0.25 11.3 7.0 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) HET PF06985.6 ETS73820.1 - 9.2e-28 97.1 0.0 2e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 ETS73821.1 - 1.8e-16 60.5 0.0 4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS73821.1 - 0.0003 20.8 0.0 0.0013 18.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS73821.1 - 0.0014 18.7 0.1 0.0083 16.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS73821.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.7 ETS73821.1 - 0.023 14.1 0.0 0.56 9.6 0.0 2.6 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) RP-C_C PF11800.3 ETS73821.1 - 0.069 12.8 0.7 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Sigma54_activat PF00158.21 ETS73821.1 - 0.093 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4363 PF14276.1 ETS73822.1 - 0.17 11.6 4.0 5.8 6.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Syntaxin PF00804.20 ETS73822.1 - 0.95 9.6 5.9 7 6.8 0.0 3.0 2 1 0 2 2 2 0 Syntaxin LdpA_C PF12617.3 ETS73823.1 - 0.096 11.9 0.4 1.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Fungal_trans_2 PF11951.3 ETS73824.1 - 1.4e-06 27.1 0.1 2.3e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS73824.1 - 0.0036 16.2 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.8 ETS73825.1 - 4.7e-17 61.3 0.0 1.2e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 ETS73825.1 - 2.2e-16 59.9 0.1 3.4e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS73825.1 - 7.9e-10 38.9 0.2 1.3e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS73825.1 - 4.4e-07 29.0 0.0 1.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 ETS73825.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 ETS73825.1 - 0.012 14.4 0.1 0.026 13.3 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Lipase_3 PF01764.20 ETS73825.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4350 PF14258.1 ETS73825.1 - 0.032 14.4 0.2 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Peptidase_S9 PF00326.16 ETS73825.1 - 0.16 11.1 0.2 0.36 10.0 0.1 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Amidohydro_2 PF04909.9 ETS73826.1 - 5e-42 144.3 0.1 6.2e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase HET PF06985.6 ETS73827.1 - 1.4e-12 47.9 0.0 5.8e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) SKG6 PF08693.5 ETS73828.1 - 0.0097 15.2 0.1 0.03 13.6 0.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Hce2 PF14856.1 ETS73829.1 - 9.9e-12 44.6 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Abhydrolase_5 PF12695.2 ETS73830.1 - 2.2e-08 33.9 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETS73830.1 - 0.00025 20.3 0.0 0.00066 18.9 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 ETS73830.1 - 0.00035 20.0 0.0 0.011 15.1 0.0 2.3 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 ETS73830.1 - 0.05 12.0 0.0 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.2 ETS73831.1 - 0.0038 16.9 0.3 0.0082 15.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF3431 PF11913.3 ETS73832.1 - 5.2e-84 281.1 0.0 6.6e-84 280.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Herpes_gE PF02480.11 ETS73833.1 - 0.00063 18.1 0.2 0.00072 17.9 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 ETS73833.1 - 0.0093 15.4 4.3 0.012 15.0 3.0 1.1 1 0 0 1 1 1 1 Vta1 like Rifin_STEVOR PF02009.11 ETS73833.1 - 0.02 14.5 0.1 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 ETS73833.1 - 0.078 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.13 ETS73833.1 - 0.31 10.8 11.5 0.67 9.7 8.0 1.7 1 1 0 1 1 1 0 Glycophorin A p450 PF00067.17 ETS73834.1 - 2.3e-49 168.2 0.0 3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Latarcin PF10279.4 ETS73834.1 - 0.025 14.7 0.1 7.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Latarcin precursor DUF2985 PF11204.3 ETS73835.1 - 3.9e-36 122.6 0.8 7.6e-36 121.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) COesterase PF00135.23 ETS73837.1 - 1.1e-85 288.4 0.0 3.3e-68 230.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS73837.1 - 1.4e-09 37.8 0.2 9.7e-09 35.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_35 PF01301.14 ETS73838.1 - 1.4e-72 244.7 0.0 3e-72 243.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS73838.1 - 7.3e-59 198.1 0.7 1.1e-58 197.6 0.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS73838.1 - 4.8e-56 187.7 5.3 1e-31 109.4 0.6 3.3 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS73838.1 - 2.6e-20 71.5 0.0 6.7e-20 70.2 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Fungal_trans PF04082.13 ETS73839.1 - 1.9e-16 59.7 0.1 3.3e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS73840.1 - 1.1e-41 142.7 39.7 2.2e-41 141.7 26.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 ETS73841.1 - 4.5e-26 91.7 0.1 5.8e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73841.1 - 1.9e-13 50.5 0.0 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73841.1 - 1e-12 48.3 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73841.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73841.1 - 0.00017 21.6 0.0 0.00033 20.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS73841.1 - 0.031 14.0 0.2 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 ETS73841.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.5 ETS73841.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidase PF01425.16 ETS73842.1 - 4.9e-89 299.1 0.0 6.4e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 ETS73843.1 - 1.1e-05 25.2 6.5 2.6e-05 24.0 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HOASN PF14515.1 ETS73843.1 - 0.091 13.1 0.6 0.21 12.0 0.4 1.7 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Abhydrolase_6 PF12697.2 ETS73844.1 - 1.9e-30 106.4 0.2 2.5e-30 106.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73844.1 - 5.1e-14 52.3 0.0 4.4e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS73844.1 - 1.4e-07 31.3 0.0 2.3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS73844.1 - 0.00013 20.5 0.0 0.00022 19.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family ArabFuran-catal PF09206.6 ETS73845.1 - 1.9e-162 539.7 22.7 2.7e-162 539.2 15.7 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 ETS73845.1 - 6.9e-60 200.8 3.2 1.1e-59 200.1 2.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) CRAL_TRIO PF00650.15 ETS73846.1 - 1.2e-39 135.4 0.0 1.6e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS73846.1 - 5.9e-11 42.3 0.1 1.6e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 ETS73846.1 - 2.8e-08 33.8 0.0 5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CUE PF02845.11 ETS73846.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 CUE domain Minor_tail_Z PF06763.6 ETS73846.1 - 0.062 12.9 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) Lactonase PF10282.4 ETS73847.1 - 2.4e-07 30.1 0.4 0.0048 16.0 0.0 3.0 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller NHL PF01436.16 ETS73847.1 - 0.047 13.6 0.0 10 6.2 0.0 3.8 3 0 0 3 3 3 0 NHL repeat OTT_1508_deam PF14441.1 ETS73848.1 - 6.4e-27 94.1 0.0 1.3e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase YCII PF03795.9 ETS73849.1 - 0.0047 17.0 0.0 0.032 14.4 0.0 2.1 1 1 1 2 2 2 1 YCII-related domain Glyco_hydro_11 PF00457.12 ETS73850.1 - 1.5e-53 180.8 15.2 1.9e-53 180.5 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-H2C2 PF09337.5 ETS73851.1 - 2.9e-21 74.6 1.8 4.7e-21 73.9 1.3 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 ETS73851.1 - 0.00017 21.5 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 ETS73851.1 - 0.00068 19.6 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS73851.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 ETS73852.1 - 5.8e-63 212.7 0.1 7e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73852.1 - 4.5e-09 36.0 10.0 8.8e-09 35.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS73853.1 - 2.8e-37 128.2 53.2 1.2e-35 122.8 36.9 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS73853.1 - 2e-12 46.1 20.0 5.3e-12 44.7 13.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4229 PF14012.1 ETS73853.1 - 0.0078 16.0 2.5 0.0078 16.0 1.8 4.3 5 0 0 5 5 5 1 Protein of unknown function (DUF4229) p450 PF00067.17 ETS73854.1 - 6.7e-07 28.1 0.0 9.4e-07 27.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS73855.1 - 1.4e-59 201.8 0.0 1.9e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS73858.1 - 1.4e-15 56.7 0.1 3.1e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.12 ETS73861.1 - 2.1e-12 46.3 0.0 7.6e-12 44.5 0.0 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 adh_short PF00106.20 ETS73864.1 - 2.5e-17 63.2 2.5 1.1e-15 57.9 1.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73864.1 - 2.5e-12 47.1 0.1 5.5e-11 42.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73864.1 - 9.6e-08 31.8 0.2 2.2e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS73864.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MOFRL PF05161.8 ETS73864.1 - 0.044 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 MOFRL family Epimerase PF01370.16 ETS73864.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 ETS73865.1 - 1.1e-10 41.0 0.0 2.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 ETS73865.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS73865.1 - 0.01 15.5 1.3 0.033 13.9 0.7 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.6 ETS73865.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Ribosomal_S26e PF01283.14 ETS73866.1 - 1.4e-50 170.3 10.0 1.6e-50 170.1 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 ETS73866.1 - 0.059 13.7 0.6 5 7.5 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 ETS73866.1 - 0.074 13.4 1.1 2.6 8.5 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1918 PF08940.6 ETS73866.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) ubiquitin PF00240.18 ETS73867.1 - 1.6e-34 117.1 0.9 2.7e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 ETS73867.1 - 1.4e-28 98.4 2.6 2.9e-28 97.4 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 ETS73867.1 - 5.9e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS73867.1 - 8.5e-06 25.9 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETS73867.1 - 0.00012 21.8 0.1 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETS73867.1 - 0.00068 19.4 0.7 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETS73867.1 - 0.0042 17.2 0.5 0.0058 16.7 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETS73867.1 - 0.057 13.4 0.7 0.1 12.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 ETS73867.1 - 0.086 11.1 2.4 2.2 6.5 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 ETS73868.1 - 3.5e-100 335.8 0.8 4e-100 335.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Endomucin PF07010.7 ETS73869.1 - 0.0083 15.4 0.4 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Endomucin Rifin_STEVOR PF02009.11 ETS73869.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family gpUL132 PF11359.3 ETS73869.1 - 1.4 8.1 4.6 2.3 7.4 3.2 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 NfeD PF01957.13 ETS73870.1 - 0.034 14.2 0.2 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DNA_pol_viral_N PF00242.12 ETS73870.1 - 1.9 7.4 4.9 3.2 6.6 3.4 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Zn_clus PF00172.13 ETS73871.1 - 1e-09 38.1 12.5 1.6e-09 37.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS73871.1 - 1.1e-09 37.3 0.1 3e-09 35.9 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 ETS73872.1 - 1.3e-58 198.1 3.6 1.3e-58 198.1 2.5 1.7 2 0 0 2 2 2 1 RTA1 like protein HemY_N PF07219.8 ETS73872.1 - 1.9 8.0 4.3 0.91 9.0 0.8 2.1 2 0 0 2 2 2 0 HemY protein N-terminus Arginase PF00491.16 ETS73873.1 - 1.4e-75 254.2 0.1 1.6e-75 253.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 ETS73874.1 - 2.4e-06 27.4 16.6 3.7e-06 26.8 11.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Ion_trans PF00520.26 ETS73874.1 - 0.041 13.1 1.2 0.041 13.1 0.8 2.9 2 1 1 3 3 3 0 Ion transport protein 7TMR-DISM_7TM PF07695.6 ETS73874.1 - 0.055 13.1 22.1 0.033 13.8 9.2 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Virul_fac_BrkB PF03631.10 ETS73874.1 - 0.11 11.8 17.5 0.037 13.3 9.0 1.9 2 0 0 2 2 2 0 Virulence factor BrkB DUF3671 PF12420.3 ETS73874.1 - 0.35 10.8 2.6 31 4.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function Glyco_transf_90 PF05686.7 ETS73876.1 - 8.7e-14 51.0 1.9 1e-11 44.1 0.2 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Ank_2 PF12796.2 ETS73878.1 - 3.6e-23 81.7 1.8 1.6e-12 47.5 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS73878.1 - 6.4e-20 69.9 10.3 2e-07 30.4 0.2 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETS73878.1 - 3.3e-17 62.1 6.8 3.4e-06 27.1 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS73878.1 - 1.4e-16 60.4 10.1 3.4e-07 30.6 0.2 4.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS73878.1 - 4.2e-16 57.4 2.2 0.00012 21.9 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF1993 PF09351.5 ETS73880.1 - 2.8e-22 79.3 0.0 3.4e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) ArsC PF03960.10 ETS73880.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 1 1 2 2 2 0 ArsC family DUF1479 PF07350.7 ETS73881.1 - 2.3e-162 540.2 0.0 2.6e-162 540.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS73881.1 - 0.025 14.6 0.3 6.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 ETS73881.1 - 0.047 13.3 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 ETS73882.1 - 0.0051 15.7 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73882.1 - 0.078 12.8 5.7 0.14 12.0 4.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2697 PF10906.3 ETS73883.1 - 0.089 12.8 0.2 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2697) But2 PF09792.4 ETS73885.1 - 1e-49 168.0 2.1 1e-49 168.0 1.5 3.5 4 0 0 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain Shisa PF13908.1 ETS73886.1 - 0.042 14.0 0.4 0.076 13.1 0.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 ETS73886.1 - 0.061 11.5 0.0 0.087 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SNF2_N PF00176.18 ETS73888.1 - 1.2e-07 30.8 0.0 1.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS73888.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 ETS73889.1 - 8.9e-16 57.5 68.5 3.3e-12 45.7 25.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 ETS73890.1 - 8.5e-30 102.7 0.2 1.4e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS73890.1 - 2.2e-23 82.2 0.0 3.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS73890.1 - 5e-08 33.8 0.1 8.4e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 ETS73890.1 - 9.6e-05 21.9 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Saccharop_dh PF03435.13 ETS73890.1 - 0.00025 20.1 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_3 PF03447.11 ETS73890.1 - 0.0064 16.8 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 ETS73890.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lyase_1 PF00206.15 ETS73890.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Lyase Reticulon PF02453.12 ETS73891.1 - 2e-19 69.8 1.2 3.6e-19 68.9 0.9 1.4 1 0 0 1 1 1 1 Reticulon MRP-S31 PF15433.1 ETS73891.1 - 0.0019 17.7 5.8 0.0028 17.1 4.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 DUF883 PF05957.8 ETS73891.1 - 0.052 13.9 2.2 2 8.8 2.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 ETS73891.1 - 7.7 6.9 9.3 65 4.0 6.4 2.4 1 1 0 1 1 1 0 YtxH-like protein GMC_oxred_C PF05199.8 ETS73892.1 - 1.3e-32 113.0 0.0 2.6e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS73892.1 - 5.9e-29 101.1 0.0 1.5e-19 70.3 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.1 ETS73892.1 - 0.0011 18.9 0.2 0.0033 17.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS73892.1 - 0.0056 16.5 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS73892.1 - 0.0083 15.0 1.5 0.31 9.8 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS73892.1 - 0.0091 14.8 0.3 0.015 14.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS73892.1 - 0.012 15.6 0.1 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS73892.1 - 0.049 13.0 0.1 0.088 12.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 ETS73893.1 - 2.2e-31 109.2 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS73893.1 - 0.00018 20.5 0.0 0.022 13.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS73893.1 - 0.0029 17.5 0.1 0.0075 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS73893.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HET PF06985.6 ETS73894.1 - 2.5e-19 69.7 0.2 5.9e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 ETS73895.1 - 3.6e-59 200.3 0.0 8e-59 199.2 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS73895.1 - 1.7e-37 128.9 0.0 2.5e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS73895.1 - 1.4e-05 24.1 0.1 0.00042 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS73895.1 - 0.0001 21.3 0.4 0.0052 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS73895.1 - 0.038 12.9 0.1 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 ETS73895.1 - 0.053 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 ETS73895.1 - 0.069 13.1 0.4 0.2 11.7 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4360 PF14273.1 ETS73896.1 - 2e-72 242.7 7.5 2.2e-72 242.5 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.16 ETS73897.1 - 5.6e-102 341.1 0.0 9.4e-102 340.3 0.0 1.3 2 0 0 2 2 2 1 Citrate synthase ICL PF00463.16 ETS73898.1 - 9.5e-197 654.3 0.0 1.1e-196 654.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS73898.1 - 4.2e-10 39.2 0.0 1.4e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 ETS73898.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain adh_short PF00106.20 ETS73899.1 - 7.2e-29 100.8 1.3 1e-28 100.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS73899.1 - 6.9e-19 68.5 0.0 9.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS73899.1 - 7.5e-11 42.0 1.3 1.1e-10 41.4 0.9 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS73899.1 - 9.4e-05 21.4 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS73899.1 - 0.00054 19.4 0.0 0.00088 18.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETS73899.1 - 0.00054 19.6 0.1 0.00096 18.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS73899.1 - 0.0024 16.6 0.1 0.014 14.1 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 ETS73899.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS73899.1 - 0.017 15.6 0.0 0.045 14.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 ETS73899.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Eno-Rase_NADH_b PF12242.3 ETS73899.1 - 0.16 11.7 2.3 0.5 10.2 0.1 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gln-synt_C PF00120.19 ETS73900.1 - 5.3e-61 206.0 0.0 6.8e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain GDC-P PF02347.11 ETS73901.1 - 2.4e-173 576.7 0.0 1.3e-160 534.8 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 ETS73901.1 - 2.7e-08 32.9 0.1 0.0015 17.3 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETS73901.1 - 1e-07 31.4 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETS73901.1 - 0.00092 17.5 0.0 0.024 12.9 0.0 2.3 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Nup54 PF13874.1 ETS73902.1 - 7.6e-40 135.8 0.3 7.6e-40 135.8 0.2 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 V-SNARE_C PF12352.3 ETS73902.1 - 0.0093 16.0 0.2 1 9.4 0.0 2.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF342 PF03961.8 ETS73902.1 - 0.1 10.9 1.5 0.19 10.1 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Nucleoporin_FG PF13634.1 ETS73902.1 - 0.89 9.8 23.7 1.6 8.9 16.4 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region CHCH PF06747.8 ETS73903.1 - 8.8e-10 38.2 15.2 1.7e-08 34.1 4.3 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 ETS73903.1 - 0.00012 21.7 11.0 0.026 14.3 0.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 ETS73903.1 - 0.73 9.9 7.4 0.76 9.8 0.9 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CAP PF00188.21 ETS73905.1 - 2e-18 67.0 5.9 4.5e-18 65.9 4.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_28 PF00295.12 ETS73906.1 - 1e-87 294.1 17.2 1.2e-87 293.9 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 WD40 PF00400.27 ETS73907.1 - 3.7e-29 99.5 5.0 1.1e-05 25.0 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETS73907.1 - 0.013 14.9 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ADH_zinc_N PF00107.21 ETS73908.1 - 3e-23 81.7 3.4 6.9e-23 80.6 0.3 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS73908.1 - 6.3e-21 74.1 4.2 1.1e-20 73.4 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 ETS73908.1 - 6e-05 23.6 0.1 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS73908.1 - 0.0012 18.5 0.5 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETS73908.1 - 0.0024 17.2 0.2 0.0044 16.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N_2 PF13602.1 ETS73908.1 - 0.02 15.8 0.6 0.04 14.8 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 ETS73908.1 - 0.027 14.4 1.2 0.06 13.3 0.3 1.8 2 0 0 2 2 2 0 TrkA-N domain HAD_2 PF13419.1 ETS73909.1 - 5.2e-21 75.6 0.0 8.6e-21 74.9 0.0 1.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS73909.1 - 7.2e-08 32.0 0.0 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS73909.1 - 1e-07 32.6 0.0 6.4e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS73909.1 - 0.00069 19.8 0.0 0.001 19.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETS73909.1 - 0.0013 18.6 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.16 ETS73910.1 - 2e-37 128.2 5.1 3.2e-37 127.6 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TP_methylase PF00590.15 ETS73911.1 - 3.4e-45 154.3 0.4 8.4e-45 153.0 0.1 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 ETS73911.1 - 3.4e-10 40.0 0.0 6.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 ETS73911.1 - 3.2e-07 29.5 0.1 5.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 ETS73911.1 - 2.6e-06 26.2 0.0 5.4e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central VSP PF03302.8 ETS73912.1 - 0.00088 18.0 0.6 0.0016 17.1 0.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4646 PF15496.1 ETS73914.1 - 0.0009 19.2 0.0 0.0098 15.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Antifungal_prot PF11402.3 ETS73915.1 - 0.01 16.0 1.1 0.02 15.0 0.7 1.5 1 0 0 1 1 1 0 Antifungal protein Imm26 PF15572.1 ETS73915.1 - 0.093 12.8 0.1 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 26 SH3_1 PF00018.23 ETS73917.1 - 2.6e-09 36.3 0.1 4.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS73917.1 - 5.9e-07 28.9 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS73917.1 - 1.5e-06 27.6 0.0 2.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.4 ETS73917.1 - 0.072 13.0 1.9 0.36 10.8 0.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) DUF4021 PF13213.1 ETS73917.1 - 0.19 11.3 0.3 0.34 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4021) DUF1516 PF07457.6 ETS73917.1 - 0.77 9.8 4.7 1.2 9.2 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) AAA_28 PF13521.1 ETS73918.1 - 0.053 13.4 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cas_GSU0054 PF09609.5 ETS73918.1 - 0.064 12.0 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Aa_trans PF01490.13 ETS73919.1 - 3.8e-93 312.1 13.0 5e-93 311.7 9.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 ETS73919.1 - 1.5e-05 23.9 18.1 1.5e-05 23.9 12.5 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TauD PF02668.11 ETS73920.1 - 4.6e-43 147.7 0.1 5.5e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.4 ETS73920.1 - 0.029 14.2 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DASH_Spc19 PF08287.6 ETS73921.1 - 3.6e-41 140.3 0.0 6e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Spc19 DUF3584 PF12128.3 ETS73921.1 - 0.00066 17.1 1.2 0.0008 16.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) COG5 PF10392.4 ETS73921.1 - 0.017 15.0 1.9 4.2 7.3 0.2 3.0 2 1 0 3 3 3 0 Golgi transport complex subunit 5 Surfac_D-trimer PF09006.6 ETS73921.1 - 0.052 13.2 0.7 1.5 8.6 0.2 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Prefoldin_2 PF01920.15 ETS73921.1 - 0.065 13.0 3.7 4.8 6.9 2.6 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlxA PF14282.1 ETS73921.1 - 0.11 12.4 2.4 0.26 11.2 0.8 2.1 1 1 1 2 2 2 0 FlxA-like protein DUF1843 PF08898.5 ETS73921.1 - 2.6 8.1 5.8 8.7 6.4 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Macoilin PF09726.4 ETS73921.1 - 3.6 5.7 6.4 12 4.0 4.4 1.6 1 1 0 1 1 1 0 Transmembrane protein TRAM_LAG1_CLN8 PF03798.11 ETS73922.1 - 2.8e-41 141.2 15.6 2.8e-41 141.2 10.8 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 ETS73922.1 - 5e-17 61.1 0.0 1.1e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Bax1-I PF01027.15 ETS73923.1 - 2.5e-49 167.6 26.1 3e-49 167.4 18.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Septin PF00735.13 ETS73924.1 - 1.8e-106 355.2 0.1 4.2e-106 354.0 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 ETS73924.1 - 0.00027 20.8 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS73924.1 - 0.0026 17.5 4.8 1 9.1 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 ETS73924.1 - 0.0048 16.1 0.3 0.015 14.4 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS73924.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETS73924.1 - 0.022 15.2 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 ETS73924.1 - 0.028 13.8 0.1 0.095 12.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 ETS73924.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 ETS73924.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 ETS73924.1 - 0.078 13.7 4.2 0.21 12.3 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS73924.1 - 0.083 13.0 0.0 0.31 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS73924.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3653 PF12375.3 ETS73924.1 - 0.26 11.5 1.6 6.6 7.0 0.5 2.6 2 1 0 2 2 2 0 Phage protein V_ATPase_I PF01496.14 ETS73924.1 - 0.93 7.2 4.1 1.3 6.8 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPA_interact_M PF14767.1 ETS73924.1 - 1.9 9.2 14.2 47 4.8 8.5 3.3 2 1 0 2 2 2 0 Replication protein A interacting middle WD40 PF00400.27 ETS73925.1 - 1.1e-10 40.9 1.0 0.0016 18.2 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat IKI3 PF04762.7 ETS73925.1 - 0.011 13.6 0.0 0.015 13.1 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Apc4_WD40 PF12894.2 ETS73925.1 - 0.095 12.2 0.0 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 ETS73925.1 - 0.15 11.1 0.1 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.17 ETS73926.1 - 7.2e-14 51.1 0.3 2e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS73926.1 - 6.1e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS73926.1 - 8.8e-05 22.2 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.6 ETS73927.1 - 2.2e-38 132.1 0.0 7.2e-38 130.4 0.0 1.8 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.10 ETS73928.1 - 4.2e-51 172.8 0.0 8.3e-51 171.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 ETS73928.1 - 0.00028 20.8 0.0 0.00082 19.3 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.6 ETS73928.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Peptidase_S10 PF00450.17 ETS73929.1 - 3.7e-85 286.5 0.2 5e-85 286.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.16 ETS73929.1 - 0.018 14.2 0.3 0.12 11.5 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family HipA_N PF07805.7 ETS73931.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 HipA-like N-terminal domain Gas_vesicle_C PF01304.12 ETS73931.1 - 0.1 12.2 1.2 0.27 10.8 0.8 1.7 1 1 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Fungal_trans PF04082.13 ETS73932.1 - 1.9e-16 59.7 0.8 2.8e-16 59.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS73932.1 - 4.6e-09 36.0 10.2 9.2e-09 35.0 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS73933.1 - 4.8e-85 285.8 0.0 6.6e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 ETS73933.1 - 3.2e-33 115.0 0.0 5.3e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETS73933.1 - 8.3e-22 77.7 0.0 1.7e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 ETS73933.1 - 4.2e-12 46.6 0.0 1.3e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 ETS73933.1 - 0.00014 21.7 0.0 0.00039 20.3 0.0 1.8 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 ETS73933.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain MPC PF03650.8 ETS73934.1 - 1.7e-42 144.1 0.5 2.4e-42 143.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 ETS73934.1 - 0.2 11.5 1.3 0.41 10.5 0.9 1.6 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.11 ETS73935.1 - 3.2e-12 45.9 0.0 4.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.6 ETS73935.1 - 0.1 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain RRM_1 PF00076.17 ETS73936.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS73936.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pol_alpha_B_N PF08418.5 ETS73936.1 - 0.65 9.4 5.8 0.69 9.4 1.8 2.2 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1687 PF07955.6 ETS73937.1 - 4.2e-19 68.8 0.3 1.3e-18 67.2 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) GST_N_2 PF13409.1 ETS73937.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain IMD PF08397.6 ETS73939.1 - 4.3e-05 22.9 3.3 0.00029 20.2 2.3 1.9 1 1 0 1 1 1 1 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.17 ETS73939.1 - 0.047 13.7 1.1 0.093 12.7 0.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.1 ETS73939.1 - 0.1 11.6 1.0 0.16 11.0 0.7 1.2 1 0 0 1 1 1 0 TMCO5 family FAD_binding_3 PF01494.14 ETS73940.1 - 3.2e-22 79.0 0.0 1.2e-21 77.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS73940.1 - 6.7e-09 35.1 1.7 2.9e-05 23.1 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS73940.1 - 9e-06 25.6 1.3 0.00012 22.0 0.8 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS73940.1 - 0.00041 20.2 0.8 0.00072 19.4 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS73940.1 - 0.00082 18.2 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 ETS73940.1 - 0.0057 15.3 0.7 0.27 9.8 0.3 2.8 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS73940.1 - 0.0096 14.8 1.2 0.016 14.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS73940.1 - 0.014 15.8 4.1 0.018 15.3 1.4 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS73940.1 - 0.084 12.9 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS73940.1 - 0.089 11.6 1.7 1.3 7.8 1.1 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 ETS73940.1 - 0.11 11.3 0.3 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PrgI PF12666.2 ETS73942.1 - 0.013 15.6 0.8 0.013 15.6 0.6 2.8 2 1 1 3 3 3 0 PrgI family protein AMP-binding PF00501.23 ETS73943.1 - 2.9e-73 246.6 0.0 3.5e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS73943.1 - 7.8e-14 52.3 0.1 2.4e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HAD_2 PF13419.1 ETS73944.1 - 4.7e-06 26.9 0.0 0.047 13.9 0.0 2.7 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS73944.1 - 1.3e-05 24.8 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Dioxygenase_C PF00775.16 ETS73945.1 - 3.5e-45 153.5 0.0 4.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS73945.1 - 1e-11 44.6 0.1 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 ETS73945.1 - 0.077 13.0 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_10 PF00331.15 ETS73946.1 - 2.5e-104 348.7 0.0 2.9e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 ETS73946.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) SnoaL_3 PF13474.1 ETS73946.1 - 0.027 14.5 0.5 0.46 10.5 0.1 2.4 2 1 0 2 2 2 0 SnoaL-like domain G6PD_C PF02781.11 ETS73946.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Glyco_hydro_62 PF03664.8 ETS73947.1 - 3.2e-75 252.7 13.6 3.8e-75 252.5 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 GDPD_2 PF13653.1 ETS73949.1 - 0.026 14.7 0.1 0.065 13.4 0.1 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family zf-MYND PF01753.13 ETS73950.1 - 0.00015 21.5 4.2 0.00015 21.5 2.9 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 ETS73950.1 - 0.0066 16.0 4.4 0.012 15.2 3.0 1.4 1 0 0 1 1 1 1 HIT zinc finger Ecl1 PF12855.2 ETS73950.1 - 0.32 10.3 9.0 0.77 9.1 6.3 1.7 1 1 0 1 1 1 0 Life-span regulatory factor Methyltrn_RNA_3 PF02598.12 ETS73951.1 - 2.6e-74 250.2 0.0 3e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.15 ETS73952.1 - 1.2e-28 98.8 0.0 1.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS73952.1 - 9.4e-07 29.0 0.1 3e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS73952.1 - 5.7e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 ETS73952.1 - 0.00032 20.2 0.1 0.089 12.3 0.1 2.2 1 1 1 2 2 2 2 Redoxin Phosducin PF02114.11 ETS73952.1 - 0.00063 18.5 0.3 0.0076 15.0 0.0 2.0 2 0 0 2 2 2 1 Phosducin AhpC-TSA PF00578.16 ETS73952.1 - 0.00076 19.1 0.1 0.0019 17.9 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 ETS73952.1 - 0.0038 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 ETS73952.1 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 ETS73952.1 - 0.11 12.4 0.2 5.8 6.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Rsm22 PF09243.5 ETS73953.1 - 3.3e-33 114.8 0.0 1.4e-31 109.5 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 ETS73953.1 - 6.5e-05 22.7 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS73953.1 - 0.004 17.7 0.8 0.063 13.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Melibiase PF02065.13 ETS73955.1 - 2.7e-05 23.0 0.0 4.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 ETS73955.1 - 0.00011 21.1 0.1 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Fungal_trans PF04082.13 ETS73956.1 - 6.2e-08 31.8 0.0 1.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 ETS73957.1 - 9.4e-131 436.4 0.0 1.1e-130 436.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 ETS73957.1 - 7e-53 178.6 0.0 1.3e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 ETS73957.1 - 0.0069 15.1 0.2 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Sugar_tr PF00083.19 ETS73958.1 - 1.5e-101 340.2 26.5 1.8e-101 339.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS73958.1 - 3.3e-27 95.1 47.5 3e-25 88.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 ETS73958.1 - 7.4e-05 21.6 0.5 7.4e-05 21.6 0.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF791) DUF948 PF06103.6 ETS73959.1 - 0.00053 19.7 0.3 0.0012 18.6 0.2 1.7 2 0 0 2 2 1 1 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 ETS73959.1 - 0.0014 18.2 1.2 0.0022 17.5 0.8 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Dor1 PF04124.7 ETS73959.1 - 0.0043 15.5 1.1 0.0058 15.1 0.8 1.1 1 0 0 1 1 1 1 Dor1-like family Prominin PF05478.6 ETS73959.1 - 0.0054 14.3 1.1 0.0072 13.9 0.8 1.1 1 0 0 1 1 1 1 Prominin Vps5 PF09325.5 ETS73959.1 - 0.011 15.0 0.2 0.037 13.2 0.1 1.8 1 1 1 2 2 2 0 Vps5 C terminal like Reo_sigmaC PF04582.7 ETS73959.1 - 0.013 14.7 5.9 0.019 14.1 4.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 ETS73959.1 - 0.018 15.4 0.7 0.35 11.3 0.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.1 ETS73959.1 - 0.02 15.2 0.1 0.038 14.2 0.1 1.5 1 1 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 ETS73959.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator LXG PF04740.7 ETS73959.1 - 0.029 14.1 2.5 0.06 13.1 1.7 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily Spc7 PF08317.6 ETS73959.1 - 0.043 12.4 0.1 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.20 ETS73959.1 - 0.083 13.0 1.4 0.19 11.8 1.0 1.6 1 1 0 1 1 1 0 Syntaxin Baculo_PEP_C PF04513.7 ETS73959.1 - 0.095 12.5 22.6 0.096 12.5 8.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3818 PF12825.2 ETS73959.1 - 0.11 11.1 1.6 0.18 10.4 0.9 1.5 1 1 1 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Mitofilin PF09731.4 ETS73959.1 - 0.12 11.0 0.5 0.16 10.5 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UPF0118 PF01594.11 ETS73959.1 - 0.12 11.3 2.5 0.18 10.7 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 LOH1CR12 PF10158.4 ETS73959.1 - 0.26 11.0 1.8 0.6 9.8 1.3 1.5 1 1 0 1 1 1 0 Tumour suppressor protein RTX PF02382.10 ETS73959.1 - 0.27 9.4 5.8 0.6 8.3 4.0 1.5 1 1 1 2 2 2 0 RTX N-terminal domain DASH_Spc19 PF08287.6 ETS73959.1 - 0.28 10.7 3.5 0.37 10.3 0.7 2.1 1 1 1 2 2 2 0 Spc19 HSBP1 PF06825.7 ETS73959.1 - 0.34 10.4 2.4 6.9 6.3 1.6 2.7 1 1 0 1 1 1 0 Heat shock factor binding protein 1 SF-assemblin PF06705.6 ETS73959.1 - 0.35 9.9 3.6 0.48 9.5 2.5 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin DASH_Duo1 PF08651.5 ETS73959.1 - 0.36 10.4 4.2 8.4 6.0 2.9 2.3 1 1 0 1 1 1 0 DASH complex subunit Duo1 HsbA PF12296.3 ETS73959.1 - 5.9 6.7 9.9 42 4.0 6.9 2.3 1 1 0 1 1 1 0 Hydrophobic surface binding protein A YjeF_N PF03853.10 ETS73960.1 - 3.2e-36 124.4 0.0 3.8e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ABC_sub_bind PF04392.7 ETS73960.1 - 0.066 12.1 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Ribosomal_S16 PF00886.14 ETS73961.1 - 5.1e-25 86.9 0.1 1.7e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S16 CPSase_L_D2 PF02786.12 ETS73962.1 - 6.1e-72 241.3 0.0 1.2e-71 240.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 ETS73962.1 - 7.9e-38 128.7 0.0 1.8e-37 127.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 ETS73962.1 - 7.7e-35 119.3 0.0 1.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 ETS73962.1 - 2.8e-16 59.1 0.0 5.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 ETS73962.1 - 4.2e-16 59.2 0.0 8.1e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 ETS73962.1 - 1.1e-15 57.0 1.9 1.1e-15 57.0 1.3 2.3 2 0 0 2 2 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ETS73962.1 - 4.5e-08 32.6 0.2 0.01 15.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 ETS73962.1 - 2.5e-06 27.0 0.0 7e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.1 ETS73962.1 - 3.9e-06 27.1 0.1 0.19 12.0 0.0 3.1 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 ETS73962.1 - 1.7e-05 24.2 0.0 3.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ETS73962.1 - 0.00064 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 ETS73962.1 - 0.0016 17.8 0.9 0.61 9.3 0.1 2.8 2 1 1 3 3 3 2 HlyD family secretion protein RimK PF08443.6 ETS73962.1 - 0.0041 16.6 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 ETS73962.1 - 0.1 11.7 2.0 2.4 7.2 0.0 2.7 2 1 1 3 3 3 0 HlyD family secretion protein Pyridox_oxidase PF01243.15 ETS73963.1 - 2.1e-13 50.0 0.0 7.1e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 ETS73963.1 - 0.001 18.9 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 ETS73963.1 - 0.0029 15.7 0.1 0.0034 15.4 0.1 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Peroxidase_2 PF01328.12 ETS73964.1 - 6.1e-48 163.1 0.5 7.6e-48 162.7 0.3 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.13 ETS73965.1 - 5.8e-08 32.5 9.4 1.1e-07 31.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS73965.1 - 1.1e-07 31.0 0.0 2.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS73966.1 - 2.1e-28 99.0 45.0 3.3e-27 95.1 11.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 ETS73967.1 - 3.6e-106 355.7 6.0 4.4e-106 355.5 4.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.20 ETS73968.1 - 1.5e-20 73.8 0.2 2.8e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS73968.1 - 2.7e-08 33.6 0.1 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS73968.1 - 1.7e-07 31.2 0.0 3.4e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS73968.1 - 1.4e-06 27.9 0.1 2.5e-06 27.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS73968.1 - 0.019 15.0 0.3 0.049 13.6 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 ETS73968.1 - 0.035 13.3 0.2 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1736 PF08409.6 ETS73968.1 - 0.13 11.8 0.7 6.9 6.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1736) Fungal_trans PF04082.13 ETS73969.1 - 2.5e-05 23.2 0.5 8e-05 21.6 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_54 PF04666.8 ETS73971.1 - 0.014 14.1 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region RRM_1 PF00076.17 ETS73972.1 - 2.5e-24 84.6 0.1 1.7e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS73972.1 - 2.1e-20 72.4 0.0 7.8e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS73972.1 - 7.2e-15 54.5 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 ETS73974.1 - 2.7e-20 72.6 0.2 1.3e-19 70.3 0.0 2.3 2 1 0 2 2 2 1 PCI domain Asp_Glu_race_2 PF14669.1 ETS73974.1 - 0.0067 15.7 1.3 0.29 10.4 0.0 2.4 2 0 0 2 2 2 2 Putative aspartate racemase EST1_DNA_bind PF10373.4 ETS73974.1 - 0.022 13.9 0.4 0.51 9.4 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain FSH1 PF03959.8 ETS73975.1 - 5.7e-64 215.4 0.0 7.2e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 ETS73975.1 - 1.7e-07 31.0 0.5 2.5e-07 30.5 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS73975.1 - 1.3e-06 28.4 3.5 3e-05 24.0 2.5 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS73975.1 - 0.0011 18.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 ETS73975.1 - 0.0023 17.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.4 ETS73975.1 - 0.017 14.3 0.6 0.17 11.1 0.7 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase Chorion_S16 PF05836.7 ETS73975.1 - 0.022 14.6 0.1 0.022 14.6 0.1 1.7 2 0 0 2 2 2 0 Chorion protein S16 Abhydrolase_2 PF02230.11 ETS73975.1 - 0.028 13.8 1.2 1.1 8.7 1.0 3.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2048 PF09752.4 ETS73975.1 - 0.035 12.9 0.1 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 ETS73975.1 - 0.05 13.8 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain AXE1 PF05448.7 ETS73975.1 - 0.13 10.7 0.1 0.21 10.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ATP-synt_J PF04911.7 ETS73976.1 - 5.6e-24 83.3 5.2 1.1e-18 66.3 0.3 2.1 1 1 1 2 2 2 2 ATP synthase j chain NIPSNAP PF07978.8 ETS73977.1 - 4.7e-39 132.4 0.3 5.7e-28 96.8 0.0 2.5 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.4 ETS73978.1 - 6.1e-69 232.1 0.0 7.1e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 ETS73979.1 - 1.2e-21 76.8 0.0 1.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 ETS73979.1 - 7.4e-14 51.0 0.0 1.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Alba Acetyltransf_7 PF13508.1 ETS73979.1 - 0.016 15.3 0.0 3.5 7.8 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 ETS73980.1 - 4.5e-21 75.7 2.0 5.5e-21 75.4 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS73980.1 - 3.5e-16 59.2 0.1 7.7e-16 58.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS73980.1 - 3.9e-05 23.4 0.0 8.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 ETS73980.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.20 ETS73980.1 - 0.052 13.1 0.1 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 ETS73980.1 - 0.13 10.6 0.0 0.82 8.1 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 ETS73980.1 - 0.34 9.7 3.6 0.081 11.7 0.2 1.7 2 1 0 2 2 2 0 Chlorophyllase enzyme Abhydro_lipase PF04083.11 ETS73980.1 - 0.41 10.0 3.6 2.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Mucin PF01456.12 ETS73982.1 - 9 6.0 22.3 11 5.7 15.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein NACHT PF05729.7 ETS73983.1 - 3e-10 40.0 0.0 8.5e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS73983.1 - 1e-07 32.1 0.1 1.2e-06 28.6 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS73983.1 - 1.3e-05 25.2 0.6 0.0003 20.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS73983.1 - 9.9e-05 22.1 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 ETS73983.1 - 0.00027 21.0 0.1 0.0015 18.6 0.0 2.4 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 ETS73983.1 - 0.00072 19.7 0.0 0.0099 16.0 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS73983.1 - 0.0009 20.0 0.0 0.0068 17.2 0.0 2.7 2 1 0 2 2 1 1 AAA domain Ank PF00023.25 ETS73983.1 - 0.0028 17.3 0.1 0.9 9.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat AAA_24 PF13479.1 ETS73983.1 - 0.0032 17.0 0.0 0.0094 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 ETS73983.1 - 0.0039 17.2 0.1 0.034 14.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 ETS73983.1 - 0.0065 16.7 0.5 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 ETS73983.1 - 0.01 14.7 0.0 0.034 13.0 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 ETS73983.1 - 0.019 15.2 0.0 0.059 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS73983.1 - 0.019 14.4 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Ank_2 PF12796.2 ETS73983.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF258 PF03193.11 ETS73983.1 - 0.041 13.0 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS73983.1 - 0.043 13.7 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 ETS73983.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 ETS73983.1 - 0.078 11.9 1.4 0.24 10.3 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Lys-AminoMut_A PF09043.6 ETS73983.1 - 0.12 10.4 0.2 0.19 9.8 0.2 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit AAA_13 PF13166.1 ETS73983.1 - 0.19 10.1 8.5 2.1 6.7 0.8 3.1 3 1 1 4 4 4 0 AAA domain AAA_23 PF13476.1 ETS73983.1 - 0.44 10.8 2.5 1.8 8.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain RPA_interact_M PF14767.1 ETS73984.1 - 0.00017 22.2 4.2 1.8 9.3 0.1 4.3 1 1 3 4 4 4 1 Replication protein A interacting middle PMI_typeI PF01238.16 ETS73984.1 - 0.0019 17.2 3.7 0.021 13.7 0.6 2.7 1 1 2 3 3 3 1 Phosphomannose isomerase type I BID PF06393.6 ETS73984.1 - 0.0054 16.1 5.9 2 7.7 0.1 4.0 1 1 4 5 5 5 2 BH3 interacting domain (BID) DUF3632 PF12311.3 ETS73984.1 - 0.037 13.8 8.1 1.4 8.7 1.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3632) Pex19 PF04614.7 ETS73984.1 - 0.06 12.9 14.5 0.18 11.3 9.6 2.0 1 1 0 1 1 1 0 Pex19 protein family DUF3731 PF12531.3 ETS73984.1 - 0.19 11.1 6.0 1.7 8.1 0.7 2.1 1 1 1 2 2 2 0 DNA-K related protein Mt_ATP-synt_B PF05405.9 ETS73984.1 - 0.31 10.4 1.6 0.75 9.2 0.2 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DinB_2 PF12867.2 ETS73984.1 - 0.32 11.3 2.5 15 5.9 0.3 2.6 1 1 1 2 2 2 0 DinB superfamily DUF1018 PF06252.7 ETS73984.1 - 0.6 10.6 7.8 5 7.6 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) DUF1631 PF07793.6 ETS73984.1 - 1.3 7.0 17.0 2.4 6.1 11.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) Dynein_heavy PF03028.10 ETS73984.1 - 1.5 6.7 4.6 1.5 6.7 0.6 1.9 1 1 1 2 2 2 0 Dynein heavy chain and region D6 of dynein motor DUF2937 PF11157.3 ETS73984.1 - 1.6 8.0 10.4 3.5 6.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF3549 PF12069.3 ETS73984.1 - 2.4 6.8 7.3 2.6 6.7 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3549) ThylakoidFormat PF11264.3 ETS73984.1 - 3.3 7.2 7.6 3.7 7.0 3.8 2.0 1 1 1 2 2 2 0 Thylakoid formation protein Rubis-subs-bind PF09273.6 ETS73984.1 - 3.5 7.5 6.7 4.4e+02 0.7 4.6 2.8 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding APH PF01636.18 ETS73984.1 - 3.8 7.1 5.4 14 5.3 1.9 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRP-alpha_N PF04086.8 ETS73984.1 - 3.8 6.7 12.2 4.9 6.4 8.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.8 ETS73984.1 - 4.1 6.5 12.6 5.9 6.0 8.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RLL PF10036.4 ETS73984.1 - 4.2 6.7 7.1 8.2 5.7 5.0 1.5 1 1 0 1 1 1 0 Putative carnitine deficiency-associated protein HemY_N PF07219.8 ETS73984.1 - 4.2 6.9 8.9 1.4 8.4 2.1 2.5 1 1 2 3 3 3 0 HemY protein N-terminus HNF-1_N PF04814.8 ETS73984.1 - 4.6 7.2 7.2 29 4.7 5.0 2.0 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cep57_MT_bd PF06657.8 ETS73984.1 - 6.2 6.8 12.7 12 5.8 0.1 4.2 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 MRI PF15325.1 ETS73984.1 - 8.8 7.3 20.8 2.6 9.0 4.9 2.2 1 1 1 2 2 2 0 Modulator of retrovirus infection Yippee-Mis18 PF03226.9 ETS73987.1 - 2.4e-17 62.7 0.4 4.5e-17 61.8 0.1 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA PF00004.24 ETS73988.1 - 2.1e-14 53.8 0.0 5.6e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS73988.1 - 3.1e-07 30.0 0.9 4e-05 23.2 0.0 3.6 4 1 0 4 4 4 1 Part of AAA domain AAA_16 PF13191.1 ETS73988.1 - 0.0018 18.2 0.1 0.0067 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS73988.1 - 0.0028 17.8 0.1 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS73988.1 - 0.01 16.6 0.0 0.23 12.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS73988.1 - 0.015 15.0 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 ETS73988.1 - 0.024 14.6 0.0 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS73988.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS73988.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 ETS73988.1 - 0.092 13.0 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETS73988.1 - 0.15 10.9 0.1 0.27 10.1 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 ETS73988.1 - 0.17 10.9 0.3 0.56 9.2 0.1 1.9 2 0 0 2 2 2 0 KaiC NPP1 PF05630.6 ETS73990.1 - 3.2e-66 223.0 3.8 3.7e-66 222.8 2.6 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 ETS73990.1 - 0.14 10.1 1.2 0.19 9.6 0.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) p450 PF00067.17 ETS73991.1 - 1.6e-69 234.6 0.0 2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 ETS73992.1 - 5.6e-16 59.2 0.1 6.5e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 EthD domain DUF4511 PF14974.1 ETS73992.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) Glyco_hydro_3 PF00933.16 ETS73995.1 - 3.1e-81 272.6 0.0 4.4e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS73995.1 - 5.3e-41 140.6 0.2 8.3e-40 136.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS73995.1 - 3.5e-20 71.6 0.1 7e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Beta-lactamase PF00144.19 ETS73996.1 - 4.8e-28 98.1 0.0 7.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M24 PF00557.19 ETS73998.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS73998.1 - 6.7e-07 29.8 0.0 1.6e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain OCD_Mu_crystall PF02423.10 ETS73999.1 - 4.5e-18 65.0 0.0 7.3e-18 64.3 0.0 1.3 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 ETS73999.1 - 0.001 19.2 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Arginosuc_synth PF00764.14 ETS74000.1 - 4.6e-39 134.5 0.0 5.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 ETS74000.1 - 2.6e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ETS74000.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Shikimate_dh_N PF08501.6 ETS74000.1 - 0.024 14.6 0.3 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain tRNA_Me_trans PF03054.11 ETS74000.1 - 0.044 12.3 0.0 0.067 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase APH PF01636.18 ETS74001.1 - 1.9e-17 63.8 0.5 3e-17 63.1 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS74001.1 - 0.00018 20.7 0.3 0.00036 19.7 0.1 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 ETS74001.1 - 0.011 14.4 0.1 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 ETS74001.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1479 PF07350.7 ETS74002.1 - 1.2e-152 508.1 0.0 1.5e-152 507.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS74002.1 - 0.0019 18.2 0.2 0.35 10.8 0.0 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 ETS74003.1 - 4.8e-08 32.2 0.1 8.7e-08 31.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 ETS74003.1 - 0.32 11.1 4.4 0.78 9.9 3.0 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Pkinase PF00069.20 ETS74005.1 - 3.7e-07 29.5 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74005.1 - 0.017 14.1 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 ETS74005.1 - 0.018 14.7 0.1 0.034 13.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 ETS74005.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 ETS74006.1 - 9e-23 80.7 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74006.1 - 2.2e-13 49.8 0.0 3.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VWA_2 PF13519.1 ETS74006.1 - 0.00082 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 ETS74006.1 - 0.016 14.9 1.3 0.051 13.2 0.0 2.3 2 1 0 2 2 2 0 von Willebrand factor type A domain YebO PF13974.1 ETS74007.1 - 0.016 14.9 2.1 0.016 14.9 1.5 2.3 2 0 0 2 2 2 0 YebO-like protein FtsX PF02687.16 ETS74007.1 - 0.14 11.8 2.6 0.29 10.8 1.8 1.4 1 0 0 1 1 1 0 FtsX-like permease family Ank PF00023.25 ETS74008.1 - 0.017 14.9 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat EHN PF06441.7 ETS74009.1 - 1.5e-30 105.3 0.0 2.6e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS74009.1 - 4.7e-11 43.0 3.4 4.7e-11 43.0 2.3 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS74009.1 - 1.4e-07 31.3 0.2 4.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS74009.1 - 0.1 12.3 0.1 0.81 9.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family HutD PF05962.6 ETS74009.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 HutD Glyco_hydro_11 PF00457.12 ETS74011.1 - 1.1e-58 197.6 14.0 1.3e-58 197.4 9.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3724 PF12521.3 ETS74011.1 - 0.027 14.1 2.8 0.18 11.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) ABC_tran PF00005.22 ETS74012.1 - 7.1e-41 139.7 0.0 3.2e-21 76.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS74012.1 - 5.7e-33 114.5 46.2 6.1e-25 88.1 14.5 3.0 4 0 0 4 4 4 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS74012.1 - 1.1e-08 35.4 0.4 0.01 15.8 0.2 3.5 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 ETS74012.1 - 9.2e-08 31.5 1.1 0.079 12.1 0.3 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS74012.1 - 0.0064 15.9 0.3 0.062 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS74012.1 - 0.0086 16.4 0.1 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS74012.1 - 0.0092 16.1 0.0 0.33 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS74012.1 - 0.01 15.8 4.3 0.7 9.8 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 ETS74012.1 - 0.025 15.4 0.0 0.068 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS74012.1 - 0.035 14.0 1.3 0.074 12.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 ETS74012.1 - 0.036 14.0 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 ETS74012.1 - 0.054 12.6 0.6 0.93 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 ETS74012.1 - 0.083 12.7 0.0 1 9.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 ETS74012.1 - 0.097 12.3 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 ETS74012.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Glu-tRNAGln PF02686.10 ETS74012.1 - 0.13 12.0 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Glyco_transf_8 PF01501.15 ETS74012.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 AAA_18 PF13238.1 ETS74012.1 - 0.2 11.9 0.0 0.54 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fic PF02661.13 ETS74014.1 - 9e-13 48.7 0.0 2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Epimerase PF01370.16 ETS74015.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Kelch_5 PF13854.1 ETS74016.1 - 3.7e-35 119.3 4.8 2.6e-08 33.6 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 ETS74016.1 - 1.2e-33 114.6 10.3 1.5e-06 27.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS74016.1 - 1.1e-28 98.6 12.4 1.8e-07 31.1 0.1 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS74016.1 - 4.2e-28 96.3 8.0 5.3e-11 42.1 0.6 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 ETS74016.1 - 2.6e-25 87.6 5.1 5.8e-07 28.9 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 ETS74016.1 - 2.2e-21 74.7 9.5 1.1e-06 28.2 0.1 6.7 6 1 0 6 6 6 4 Kelch motif RAG2 PF03089.9 ETS74016.1 - 0.0069 15.1 0.3 0.47 9.1 0.0 3.4 4 1 0 4 4 4 1 Recombination activating protein 2 Vac_Fusion PF02346.11 ETS74016.1 - 3.5 7.1 7.0 3.4 7.1 0.0 4.0 4 0 0 4 4 4 0 Chordopoxvirus fusion protein Raptor_N PF14538.1 ETS74017.1 - 6.9e-64 214.3 0.0 1.3e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 ETS74017.1 - 3e-08 33.2 4.3 0.51 10.3 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETS74017.1 - 0.0012 18.5 0.2 0.057 13.2 0.1 2.7 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 ETS74017.1 - 0.0013 18.9 0.9 0.0096 16.1 0.1 2.7 3 0 0 3 3 3 1 HEAT repeats HRXXH PF13933.1 ETS74018.1 - 5.8e-102 340.3 0.0 8.2e-102 339.8 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family SSP160 PF06933.6 ETS74019.1 - 4.1 5.2 21.9 0.82 7.5 5.8 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Zip PF02535.17 ETS74020.1 - 4e-28 98.3 42.9 9.6e-12 44.5 5.2 3.6 3 1 1 4 4 4 3 ZIP Zinc transporter OTT_1508_deam PF14441.1 ETS74021.1 - 8.1e-09 35.4 0.1 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase KSR1-SAM PF13543.1 ETS74021.1 - 0.022 14.5 0.1 0.091 12.5 0.0 2.0 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Dynamin_N PF00350.18 ETS74022.1 - 2.9e-29 102.0 0.0 6.5e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS74022.1 - 5.3e-17 61.5 0.2 1.5e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 ETS74022.1 - 0.00012 22.0 0.0 0.0021 18.0 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS74022.1 - 0.0027 18.1 0.0 0.021 15.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 ETS74022.1 - 0.016 15.2 0.0 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS74022.1 - 0.016 15.5 0.3 4.3 7.6 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.1 ETS74022.1 - 0.026 14.8 0.1 0.79 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain p450 PF00067.17 ETS74023.1 - 7.2e-39 133.5 0.0 8.6e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.9 ETS74025.1 - 5.7e-24 83.8 2.8 1.7e-10 40.7 0.0 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.20 ETS74028.1 - 6.2e-24 84.7 0.2 1.2e-23 83.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74028.1 - 9.4e-18 64.8 0.1 1.7e-16 60.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74028.1 - 1e-07 31.8 0.1 2.1e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS74028.1 - 0.0056 16.1 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 ETS74029.1 - 2.2e-67 223.4 7.5 1.5e-19 70.0 0.0 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74029.1 - 1.9e-61 200.9 18.5 4.5e-07 29.3 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.1 ETS74029.1 - 3.9e-47 153.5 3.2 5.8e-05 22.9 0.0 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 ETS74029.1 - 5.2e-38 128.7 6.0 2.3e-08 34.3 0.1 6.8 4 1 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS74029.1 - 6.5e-28 96.1 16.6 0.0003 20.9 0.0 9.8 1 1 9 10 10 10 7 Ankyrin repeats (many copies) DUF4350 PF14258.1 ETS74029.1 - 0.0036 17.4 2.9 50 4.2 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4350) Mur_ligase PF01225.20 ETS74029.1 - 0.015 15.3 3.8 1.1 9.3 0.9 4.0 3 1 0 3 3 3 0 Mur ligase family, catalytic domain Methyltransf_29 PF03141.11 ETS74029.1 - 0.12 10.7 0.2 19 3.3 0.0 3.6 3 1 2 5 5 5 0 Putative S-adenosyl-L-methionine-dependent methyltransferase INTS5_C PF14838.1 ETS74029.1 - 0.23 9.7 0.0 1.2 7.3 0.0 2.0 1 1 1 2 2 2 0 Integrator complex subunit 5 C-terminus HET PF06985.6 ETS74030.1 - 1.8e-35 122.0 0.4 2.7e-35 121.5 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS74031.1 - 8.3e-22 77.3 36.8 8.9e-13 47.6 5.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74031.1 - 0.0024 16.5 7.3 0.0024 16.5 5.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Bax1-I PF01027.15 ETS74031.1 - 0.56 9.7 20.5 0.074 12.6 5.8 3.1 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 HET PF06985.6 ETS74032.1 - 2.7e-23 82.6 0.3 5.5e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS74033.1 - 3.2e-70 232.5 4.6 5.6e-22 77.8 0.0 6.1 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS74033.1 - 8.4e-68 223.6 7.7 1.2e-14 54.3 0.0 8.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.25 ETS74033.1 - 1.1e-67 220.6 19.1 2.2e-10 39.7 0.1 11.4 10 1 1 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 ETS74033.1 - 1.2e-51 167.5 13.7 2e-07 30.5 0.0 11.9 11 1 1 12 12 10 8 Ankyrin repeat Ank_5 PF13857.1 ETS74033.1 - 5.4e-49 163.1 10.2 5.3e-11 42.4 0.0 8.0 3 2 4 7 7 7 7 Ankyrin repeats (many copies) NACHT PF05729.7 ETS74033.1 - 1.3e-09 37.9 0.1 4.4e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS74033.1 - 6.9e-07 29.4 0.1 2.7e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS74033.1 - 5.1e-05 23.4 0.0 0.0002 21.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.9 ETS74033.1 - 6.1e-05 22.1 0.2 0.043 12.8 0.0 2.8 3 0 0 3 3 3 2 KAP family P-loop domain ABC_tran PF00005.22 ETS74033.1 - 0.0084 16.4 0.0 0.036 14.3 0.0 2.0 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETS74033.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 ETS74033.1 - 0.033 13.6 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 ETS74033.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.11 ETS74033.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase ArgK PF03308.11 ETS74033.1 - 0.099 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 ETS74033.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS74033.1 - 0.15 12.8 0.9 0.61 10.9 0.1 2.5 2 1 0 2 2 1 0 AAA domain DUF3962 PF13111.1 ETS74033.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) DUF2075 PF09848.4 ETS74033.1 - 0.24 10.3 0.3 1.1 8.0 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) p450 PF00067.17 ETS74034.1 - 2.1e-06 26.5 0.0 2.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS74035.1 - 1.7e-28 99.5 0.3 2.8e-28 98.8 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 ETS74037.1 - 4.7e-17 62.4 0.0 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS74037.1 - 0.0015 18.2 0.3 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS74037.1 - 0.0091 15.9 0.8 0.03 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS74037.1 - 0.0093 16.1 1.6 0.086 12.9 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 ETS74037.1 - 0.018 14.7 0.2 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS74037.1 - 0.023 15.5 0.0 0.13 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS74037.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETS74037.1 - 0.065 12.9 0.2 9.1 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 ETS74037.1 - 0.07 12.7 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETS74037.1 - 0.095 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PNP_UDP_1 PF01048.15 ETS74038.1 - 8.8e-17 60.8 0.1 5.8e-16 58.1 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Arylsulfotran_2 PF14269.1 ETS74039.1 - 3.3e-47 161.0 0.1 4.7e-47 160.5 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS74039.1 - 4.2e-10 38.7 0.0 8.1e-10 37.8 0.0 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans_2 PF11951.3 ETS74040.1 - 0.0018 16.9 1.4 0.003 16.2 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Metallophos PF00149.23 ETS74041.1 - 1.5e-12 47.3 0.0 2.8e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS74041.1 - 1.8e-09 37.6 0.1 4.6e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1652 PF07865.6 ETS74041.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF4131 PF13567.1 ETS74041.1 - 0.14 11.5 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ctr PF04145.10 ETS74041.1 - 0.15 12.1 0.1 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family Pet191_N PF10203.4 ETS74042.1 - 1.7e-15 56.7 0.2 2.4e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydro_lipase PF04083.11 ETS74043.1 - 2.1e-22 78.2 0.1 4.6e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 ETS74043.1 - 6e-18 65.2 0.1 8.2e-17 61.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS74043.1 - 0.00068 19.4 0.0 0.0069 16.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 ETS74043.1 - 0.0019 17.6 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DUF605 PF04652.11 ETS74043.1 - 0.49 9.7 12.4 1.3 8.3 6.6 2.0 2 0 0 2 2 2 0 Vta1 like Transaldolase PF00923.14 ETS74044.1 - 4.7e-95 318.0 1.5 5.4e-95 317.8 1.0 1.0 1 0 0 1 1 1 1 Transaldolase SNase PF00565.12 ETS74045.1 - 2.3e-68 227.3 5.7 4.2e-21 75.2 0.2 5.7 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 ETS74045.1 - 8.9e-27 93.3 0.3 6.6e-26 90.5 0.0 2.5 3 0 0 3 3 3 1 Tudor domain SMN PF06003.7 ETS74045.1 - 1.6e-06 27.4 0.2 4.3e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 ETS74046.1 - 4.1e-44 150.1 5.4 4.8e-44 149.9 3.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.17 ETS74047.1 - 2.7e-63 213.9 0.0 4.1e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 ETS74047.1 - 4.4e-29 101.6 1.6 8e-29 100.7 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 ETS74047.1 - 1.2e-11 44.6 0.0 8.8e-10 38.6 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETS74047.1 - 9e-06 25.8 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Tropomyosin PF00261.15 ETS74047.1 - 0.26 10.3 2.9 0.45 9.5 2.0 1.3 1 0 0 1 1 1 0 Tropomyosin Het-C PF07217.6 ETS74048.1 - 1.6e-156 522.0 0.0 2e-156 521.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.13 ETS74048.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C DDE_Tnp_ISAZ013 PF07592.6 ETS74048.1 - 0.071 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Meleagrin PF08189.6 ETS74049.1 - 0.017 14.6 2.6 0.039 13.4 1.8 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family DUF1180 PF06679.7 ETS74049.1 - 0.11 12.4 1.3 0.15 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Asparaginase_2 PF01112.13 ETS74050.1 - 1e-84 284.0 7.7 1.2e-84 283.7 5.4 1.0 1 0 0 1 1 1 1 Asparaginase CFEM PF05730.6 ETS74051.1 - 3.3e-05 23.6 8.9 5.6e-05 22.8 1.1 3.2 2 0 0 2 2 2 2 CFEM domain Ank_5 PF13857.1 ETS74052.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) E1-E2_ATPase PF00122.15 ETS74054.1 - 2.4e-53 180.5 1.7 2.4e-53 180.5 1.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS74054.1 - 5.7e-39 133.5 5.3 5.7e-39 133.5 3.7 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS74054.1 - 6.5e-31 108.4 0.0 1.7e-29 103.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS74054.1 - 1.3e-17 63.4 0.0 2.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS74054.1 - 7.5e-13 49.0 0.0 2.3e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS74054.1 - 1.5e-11 43.5 0.0 3.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS74054.1 - 6.4e-05 22.6 1.0 0.00018 21.2 0.6 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAM176 PF14851.1 ETS74054.1 - 0.43 10.2 1.7 27 4.4 0.0 2.6 2 0 0 2 2 2 0 FAM176 family Chitin_bind_3 PF03067.10 ETS74055.1 - 4.1e-05 23.9 0.1 0.00015 22.0 0.1 1.8 1 1 0 1 1 1 1 Chitin binding domain Peptidase_S41 PF03572.13 ETS74056.1 - 3.9e-08 32.9 0.0 1.6e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 CutC PF03932.9 ETS74056.1 - 0.068 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 CutC family DUF3328 PF11807.3 ETS74058.1 - 2.6e-37 128.6 0.1 3.6e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.22 ETS74059.1 - 4e-51 172.9 0.1 2.6e-27 95.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS74059.1 - 2.6e-25 89.3 28.9 3.3e-19 69.3 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS74059.1 - 4.8e-13 49.7 3.9 2.2e-05 24.5 0.0 4.7 3 2 0 5 5 4 3 AAA domain SMC_N PF02463.14 ETS74059.1 - 8.1e-12 44.8 4.4 2.3e-05 23.7 0.5 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 ETS74059.1 - 1.4e-05 24.1 0.2 0.0052 15.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS74059.1 - 6.5e-05 23.0 0.3 0.66 10.1 0.0 3.4 4 1 0 4 4 2 2 AAA domain Zeta_toxin PF06414.7 ETS74059.1 - 7.2e-05 21.9 0.1 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 ETS74059.1 - 0.00015 22.0 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS74059.1 - 0.00015 22.5 0.5 0.18 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS74059.1 - 0.00016 21.1 2.1 0.41 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 ETS74059.1 - 0.0002 21.8 0.2 0.47 10.9 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 ETS74059.1 - 0.0004 20.3 0.4 0.3 11.0 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 ETS74059.1 - 0.00046 19.6 0.9 0.046 13.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 ETS74059.1 - 0.00053 20.0 0.4 0.64 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETS74059.1 - 0.00054 19.1 1.3 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETS74059.1 - 0.00063 19.5 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 ETS74059.1 - 0.00089 18.9 1.0 0.51 10.0 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 ETS74059.1 - 0.00094 18.6 0.7 0.98 8.7 0.1 2.9 3 0 0 3 3 3 2 AAA-like domain NTPase_1 PF03266.10 ETS74059.1 - 0.0013 18.4 1.6 0.75 9.4 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA PF00004.24 ETS74059.1 - 0.0016 18.6 0.3 0.48 10.6 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS74059.1 - 0.002 17.0 1.0 0.31 9.8 0.3 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 ETS74059.1 - 0.0097 15.6 0.8 0.11 12.2 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_25 PF13481.1 ETS74059.1 - 0.016 14.6 0.3 2 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETS74059.1 - 0.016 15.0 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 ETS74059.1 - 0.018 14.9 0.1 2 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS74059.1 - 0.019 15.3 2.2 2.7 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS74059.1 - 0.019 14.5 0.2 0.78 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETS74059.1 - 0.02 14.8 0.9 0.54 10.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain SbcCD_C PF13558.1 ETS74059.1 - 0.02 14.7 0.1 0.41 10.6 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRPRB PF09439.5 ETS74059.1 - 0.022 13.9 0.4 3 7.0 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 ETS74059.1 - 0.033 13.6 0.0 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 ETS74059.1 - 0.037 13.4 0.7 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 ETS74059.1 - 0.038 13.6 0.2 0.99 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.9 ETS74059.1 - 0.15 11.0 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.4 ETS74059.1 - 0.18 11.2 1.7 0.96 8.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 ETS74059.1 - 0.32 10.7 3.1 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 ETS74059.1 - 0.33 9.9 0.0 19 4.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 ETS74060.1 - 2.3e-72 243.2 0.0 3.8e-72 242.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74060.1 - 1.6e-36 125.7 0.1 9.3e-33 113.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS74060.1 - 7.4e-07 28.4 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS74060.1 - 0.0027 17.4 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS74060.1 - 0.0065 16.0 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 ETS74060.1 - 0.013 14.5 0.0 0.037 13.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 ETS74060.1 - 0.088 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC SMC_N PF02463.14 ETS74061.1 - 2.6e-23 82.4 0.0 5.5e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS74061.1 - 2.9e-12 47.3 18.2 2.9e-12 47.3 12.6 5.3 3 2 1 4 4 2 1 AAA domain AAA_21 PF13304.1 ETS74061.1 - 2.1e-08 34.5 1.2 5.5e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 ETS74061.1 - 8e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF465 PF04325.8 ETS74061.1 - 0.00056 19.5 0.9 0.00056 19.5 0.6 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF465) AAA_25 PF13481.1 ETS74061.1 - 0.0024 17.3 0.0 0.011 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain Cauli_AT PF03233.8 ETS74061.1 - 0.015 15.0 0.5 0.015 15.0 0.4 5.3 4 1 0 4 4 4 0 Aphid transmission protein SRP54 PF00448.17 ETS74061.1 - 0.017 14.5 2.4 0.37 10.1 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.24 ETS74061.1 - 0.023 14.9 0.1 0.23 11.6 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS74061.1 - 0.027 14.5 2.3 1.3 9.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 ETS74061.1 - 0.16 11.1 9.5 1.1 8.3 0.3 4.1 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETS74061.1 - 0.21 11.3 13.7 7.1 6.4 0.7 4.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.1 ETS74061.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.8 3 1 1 4 4 4 0 AAA ATPase domain AAA_17 PF13207.1 ETS74061.1 - 0.54 11.0 0.0 0.54 11.0 0.0 4.1 3 2 0 3 3 2 0 AAA domain L27_1 PF09058.5 ETS74061.1 - 1.5 8.7 10.8 2.7 7.9 0.5 3.5 3 0 0 3 3 3 0 L27_1 zf-CCHC PF00098.18 ETS74062.1 - 3.9e-07 29.6 2.9 7.5e-07 28.7 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Glyco_hydro_43 PF04616.9 ETS74063.1 - 2.2e-64 217.2 0.4 2.6e-64 217.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF946 PF06101.6 ETS74064.1 - 1.9e-08 32.7 0.2 2.7e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Protocadherin PF08374.6 ETS74064.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protocadherin HET PF06985.6 ETS74065.1 - 1.1e-20 74.2 0.1 1.9e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Patatin PF01734.17 ETS74066.1 - 1.2e-24 87.3 0.2 4.1e-24 85.6 0.0 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase Ras PF00071.17 ETS74067.1 - 1e-40 138.7 0.1 1.7e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS74067.1 - 1.8e-14 54.2 0.0 3.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS74067.1 - 0.00019 20.7 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF629 PF04780.7 ETS74067.1 - 0.00039 19.0 1.8 0.00075 18.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF629) MMR_HSR1 PF01926.18 ETS74067.1 - 0.0033 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS74067.1 - 0.016 14.6 0.0 0.1 11.9 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain zf-Di19 PF05605.7 ETS74067.1 - 0.021 14.9 4.8 1.2 9.3 0.5 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SRPRB PF09439.5 ETS74067.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Vps39_2 PF10367.4 ETS74067.1 - 0.089 12.9 2.6 8.1 6.6 0.1 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_4 PF13894.1 ETS74067.1 - 0.11 12.9 15.6 5.3 7.6 0.4 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Pro-MCH PF05824.7 ETS74067.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) Fra10Ac1 PF09725.4 ETS74067.1 - 0.54 10.3 3.1 0.29 11.2 0.5 1.8 2 0 0 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 DZR PF12773.2 ETS74067.1 - 0.93 9.3 4.4 3.2 7.6 1.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_2 PF12756.2 ETS74067.1 - 0.99 9.5 7.0 6.1 7.0 0.9 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 ETS74067.1 - 3.7 7.8 9.5 0.46 10.7 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 ETS74067.1 - 4.7 7.4 10.2 0.4 10.9 0.3 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3505) Sugar_tr PF00083.19 ETS74068.1 - 2e-69 234.3 29.9 2.5e-69 234.0 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74068.1 - 3.3e-23 81.9 44.7 4.3e-16 58.5 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 ETS74069.1 - 3.1e-44 151.3 0.1 4.4e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS74069.1 - 8.5e-08 32.1 0.1 8.2e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS74069.1 - 3.4e-07 30.3 0.0 0.00089 19.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS74069.1 - 5.3e-06 25.5 0.1 0.00051 18.9 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 ETS74069.1 - 0.00095 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS74069.1 - 0.0014 18.7 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS74069.1 - 0.0027 17.4 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS74069.1 - 0.0059 15.2 0.0 0.21 10.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 ETS74069.1 - 0.018 13.9 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 ETS74069.1 - 0.019 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 ETS74069.1 - 0.022 14.7 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 ETS74069.1 - 0.056 13.8 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS74069.1 - 0.061 11.7 0.0 1.6 7.0 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 ETS74069.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 ETS74069.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GBP_PSP PF02425.10 ETS74069.1 - 0.3 10.6 2.0 1.2 8.7 0.5 2.6 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide DUF1338 PF07063.8 ETS74070.1 - 2.9e-76 256.4 0.0 3.6e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF1450 PF07293.6 ETS74070.1 - 0.14 12.1 0.0 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) 2-Hacid_dh_C PF02826.14 ETS74071.1 - 2.7e-58 196.0 0.0 3.7e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS74071.1 - 7.4e-20 70.7 0.0 9.1e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS74071.1 - 4.5e-09 36.3 0.3 2.4e-08 33.9 0.1 2.2 2 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS74071.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ETS74071.1 - 0.032 13.5 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 ETS74071.1 - 0.038 13.4 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Asp_Glu_race PF01177.17 ETS74072.1 - 4e-11 43.2 0.1 3.2e-06 27.2 0.0 2.0 1 1 1 2 2 2 2 Asp/Glu/Hydantoin racemase Aldolase_II PF00596.16 ETS74073.1 - 2.3e-48 164.2 0.0 3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 ETS74074.1 - 3.9e-32 111.1 0.0 7e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74074.1 - 0.021 14.7 4.4 0.049 13.5 3.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 ETS74075.1 - 2.9e-25 89.0 0.1 4e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS74075.1 - 2e-11 43.1 0.0 1.4e-10 40.3 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS74075.1 - 0.0024 17.6 1.8 0.0051 16.5 1.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETS74075.1 - 0.0047 15.7 0.6 0.17 10.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family 3D PF06725.6 ETS74075.1 - 0.013 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 3D domain AAA_16 PF13191.1 ETS74076.1 - 6.8e-10 39.2 0.9 2e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Asp_protease_2 PF13650.1 ETS74076.1 - 3.2e-08 33.9 0.4 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease AAA_22 PF13401.1 ETS74076.1 - 7.8e-07 29.3 1.3 2.3e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETS74076.1 - 8.8e-07 28.0 0.0 1.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain gag-asp_proteas PF13975.1 ETS74076.1 - 4.2e-06 26.4 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 ETS74076.1 - 0.00029 20.3 0.0 0.055 13.0 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease Arch_ATPase PF01637.13 ETS74076.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase RVP PF00077.15 ETS74076.1 - 0.007 16.2 0.0 8.7 6.3 0.0 3.2 3 1 0 3 3 3 2 Retroviral aspartyl protease Cytochrom_B_C PF00032.12 ETS74077.1 - 0.11 12.7 3.7 0.2 11.8 2.6 1.5 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD VIT1 PF01988.14 ETS74077.1 - 1.2 8.5 7.1 2.3 7.6 4.9 1.4 1 0 0 1 1 1 0 VIT family DUF2975 PF11188.3 ETS74077.1 - 1.6 8.4 12.4 0.57 9.9 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) PNP_UDP_1 PF01048.15 ETS74078.1 - 8.8e-17 60.8 0.2 4.1e-16 58.6 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily MAT1 PF06391.8 ETS74078.1 - 0.087 12.3 1.7 6.4 6.3 0.1 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 TPR_10 PF13374.1 ETS74079.1 - 1.7e-47 158.0 6.0 5.1e-10 38.9 0.1 7.6 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 ETS74079.1 - 1.7e-35 120.7 13.7 9.1e-10 38.3 0.1 6.5 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS74079.1 - 3e-09 36.4 0.4 0.014 15.0 0.0 4.1 3 1 1 4 4 3 3 TPR repeat TPR_16 PF13432.1 ETS74079.1 - 5.5e-08 33.2 1.8 0.52 11.0 0.0 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS74079.1 - 1.2e-07 30.9 10.0 0.016 14.9 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETS74079.1 - 1.9e-07 31.3 0.0 7.9e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 ETS74079.1 - 1.4e-06 27.6 13.9 0.11 12.1 0.1 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS74079.1 - 4.2e-05 23.4 3.6 3.2 8.1 0.1 5.9 5 1 0 5 5 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 ETS74079.1 - 0.002 17.0 0.0 0.81 8.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_20 PF14561.1 ETS74079.1 - 0.0063 16.6 0.9 0.1 12.7 0.1 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS74079.1 - 0.011 16.0 6.0 3 8.2 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS74079.1 - 0.011 15.8 7.5 1.1 9.4 0.2 3.6 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETS74079.1 - 0.012 15.4 0.6 0.012 15.4 0.5 5.3 8 0 0 8 8 5 0 Tetratricopeptide repeat AAA_25 PF13481.1 ETS74079.1 - 0.037 13.4 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma70_ner PF04546.8 ETS74079.1 - 0.12 12.0 7.6 0.049 13.2 3.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_8 PF13181.1 ETS74079.1 - 0.18 11.6 6.8 2.5 8.0 0.7 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 ETS74079.1 - 0.31 10.8 15.8 0.37 10.6 1.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 ETS74079.1 - 0.43 10.8 14.2 0.056 13.6 6.3 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PPR PF01535.15 ETS74079.1 - 0.8 9.8 2.9 7.3 6.8 0.0 3.7 4 0 0 4 4 3 0 PPR repeat NOA36 PF06524.7 ETS74079.1 - 7 5.8 13.7 16 4.6 9.5 1.5 1 0 0 1 1 1 0 NOA36 protein COesterase PF00135.23 ETS74080.1 - 2.9e-87 293.5 0.0 3.7e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS74080.1 - 1.7e-09 37.5 1.2 8.6e-09 35.2 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS74080.1 - 0.0011 18.2 0.1 0.0028 16.9 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family LigB PF02900.13 ETS74081.1 - 1.7e-45 155.1 0.1 2e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 ETS74082.1 - 0.00035 20.5 0.1 0.00091 19.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS74082.1 - 0.0018 18.3 0.1 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS74082.1 - 0.026 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 ETS74082.1 - 0.027 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 ETS74082.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS74082.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 ETS74083.1 - 4.7e-49 167.0 0.1 6.3e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74083.1 - 4.1e-08 32.9 7.0 8.8e-08 31.9 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.6 ETS74084.1 - 0.031 15.2 0.1 0.45 11.4 0.0 2.1 1 1 0 1 1 1 0 EthD domain Glyco_hydro_28 PF00295.12 ETS74085.1 - 8.8e-32 110.3 0.1 1.5e-31 109.5 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.20 ETS74086.1 - 2.1e-48 164.7 0.0 4.1e-45 153.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74086.1 - 1.4e-31 109.5 0.0 3.5e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 ETS74086.1 - 0.00029 19.7 0.1 0.00051 18.9 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 ETS74086.1 - 0.00066 18.7 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETS74086.1 - 0.15 10.8 0.1 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SUR7 PF06687.7 ETS74087.1 - 5.8e-29 101.1 11.5 7.7e-29 100.7 7.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 ETS74087.1 - 0.0037 16.9 15.6 0.0037 16.9 10.8 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 ETS74087.1 - 0.065 12.8 0.2 0.065 12.8 0.2 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Clc-like PF07062.7 ETS74087.1 - 0.52 9.5 7.3 0.037 13.2 1.2 1.7 2 0 0 2 2 2 0 Clc-like Zn_clus PF00172.13 ETS74088.1 - 3.8e-08 33.0 4.1 5.4e-08 32.6 2.9 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSSP PF03940.8 ETS74088.1 - 0.23 10.8 6.1 0.38 10.1 4.2 1.3 1 0 0 1 1 1 0 Male specific sperm protein Fungal_trans_2 PF11951.3 ETS74089.1 - 1.5e-18 66.5 0.0 4.1e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Molybdopterin PF00384.17 ETS74089.1 - 0.063 11.9 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase RE_HpaII PF09561.5 ETS74089.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 HpaII restriction endonuclease Dioxygenase_C PF00775.16 ETS74090.1 - 9.9e-12 44.4 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase ADH_N PF08240.7 ETS74091.1 - 7.6e-11 41.7 0.0 2.6e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS74091.1 - 2.2e-08 33.7 0.1 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS74091.1 - 0.04 13.7 0.5 0.097 12.4 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FixQ PF05545.6 ETS74092.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Kinesin PF00225.18 ETS74093.1 - 8.4e-78 261.4 3.4 1.1e-77 261.0 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Filament PF00038.16 ETS74093.1 - 0.2 11.1 37.3 2.9 7.2 24.3 3.1 2 1 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.7 ETS74093.1 - 1.9 8.2 12.1 0.77 9.5 3.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 ETS74093.1 - 1.9 8.4 14.5 0.78 9.6 0.4 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CASP_C PF08172.7 ETS74094.1 - 0.33 9.9 5.5 0.66 8.9 3.8 1.5 1 0 0 1 1 1 0 CASP C terminal AhpC-TSA_2 PF13911.1 ETS74095.1 - 3.5e-16 59.1 0.1 6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 ETS74095.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 ETS74095.1 - 0.00034 20.1 0.0 0.0013 18.3 0.0 1.8 1 1 1 2 2 2 1 Redoxin PAP_assoc PF03828.14 ETS74096.1 - 6.9e-16 57.9 0.1 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETS74096.1 - 4.2e-05 23.7 0.0 8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.9 ETS74097.1 - 4.9e-18 64.8 1.3 6.5e-18 64.4 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme YmaF PF12788.2 ETS74097.1 - 0.027 14.5 0.2 0.039 14.1 0.2 1.2 1 0 0 1 1 1 0 YmaF family RNA_POL_M_15KD PF02150.11 ETS74097.1 - 0.74 9.5 4.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit HET PF06985.6 ETS74098.1 - 7.1e-18 65.1 5.1 5.2e-15 55.8 1.6 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4528 PF15031.1 ETS74098.1 - 0.052 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) MCLC PF05934.6 ETS74099.1 - 6.2 4.9 7.3 9.5 4.3 5.1 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) OPT PF03169.10 ETS74101.1 - 1.6e-173 578.5 57.5 1.9e-173 578.2 39.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RAMP4 PF06624.7 ETS74101.1 - 0.061 12.8 0.9 12 5.5 0.0 2.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF3480 PF11979.3 ETS74101.1 - 0.098 11.2 0.1 0.26 9.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) SH3_1 PF00018.23 ETS74102.1 - 1.8e-15 56.0 0.4 2.8e-15 55.4 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS74102.1 - 1e-10 41.0 0.1 1.5e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS74102.1 - 3.6e-10 39.1 0.0 5.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.6 ETS74102.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) EAF PF09816.4 ETS74103.1 - 2.8e-17 62.6 0.2 9e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor DUF4278 PF14105.1 ETS74103.1 - 0.13 12.2 0.4 0.53 10.2 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) Cwf_Cwc_15 PF04889.7 ETS74103.1 - 0.81 9.3 24.5 0.64 9.6 5.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein adh_short PF00106.20 ETS74104.1 - 1.4e-26 93.3 0.4 1.9e-26 93.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74104.1 - 6.2e-24 85.0 0.0 7.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74104.1 - 2.7e-07 30.4 0.2 4.2e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 ETS74104.1 - 0.0016 17.4 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS74104.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ala_racemase_N PF01168.15 ETS74105.1 - 9.3e-28 97.2 0.3 1.1e-27 96.9 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 ETS74105.1 - 2.1e-18 66.3 0.0 4.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain UPF0081 PF03652.10 ETS74105.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Na_Ca_ex PF01699.19 ETS74106.1 - 9.5e-49 164.5 29.9 6.5e-26 90.6 6.6 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Peptidase_C21 PF05381.7 ETS74106.1 - 0.0057 16.7 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Tymovirus endopeptidase ABC2_membrane_2 PF12679.2 ETS74106.1 - 0.11 11.3 13.5 0.12 11.2 0.3 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.1 ETS74106.1 - 4 6.8 6.3 7.4 5.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glyoxalase PF00903.20 ETS74107.1 - 2.7e-40 137.3 0.3 4.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS74107.1 - 4.5e-32 110.8 0.2 8.2e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETS74107.1 - 1.2e-18 67.0 0.0 9.2e-08 32.0 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ETS74107.1 - 1.5e-06 28.2 0.0 0.045 13.6 0.0 3.3 2 1 1 3 3 3 2 Glyoxalase-like domain CppA_N PF14506.1 ETS74107.1 - 0.058 13.0 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal 2-Hacid_dh_C PF02826.14 ETS74108.1 - 1.9e-51 173.7 0.0 2.9e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS74108.1 - 1.4e-32 111.9 0.0 2.3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.1 ETS74109.1 - 4.5e-10 39.8 0.5 5.7e-10 39.4 0.4 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS74109.1 - 2.2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 ETS74109.1 - 1.3e-05 23.8 0.0 1.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 HIM1 3Beta_HSD PF01073.14 ETS74109.1 - 6.4e-05 21.7 0.0 0.00019 20.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETS74109.1 - 8.4e-05 21.9 0.5 0.00026 20.3 0.4 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 ETS74109.1 - 0.00013 20.9 0.0 0.19 10.6 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 ETS74109.1 - 0.028 14.7 0.0 0.062 13.6 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SelR PF01641.13 ETS74110.1 - 2.4e-49 166.1 0.0 2.8e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 ETS74110.1 - 0.014 15.1 0.4 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 ETS74110.1 - 0.017 14.4 1.6 0.31 10.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 ETS74110.1 - 0.026 14.5 0.6 0.1 12.6 0.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.1 ETS74110.1 - 0.14 12.4 2.5 13 6.1 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.2 ETS74110.1 - 0.17 11.6 3.9 8.5 6.2 0.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.1 ETS74110.1 - 0.18 11.6 2.3 14 5.6 0.1 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Isochorismatase PF00857.15 ETS74112.1 - 1.8e-41 142.0 0.0 2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Ferrochelatase PF00762.14 ETS74112.1 - 0.046 12.6 0.2 0.4 9.6 0.1 2.0 2 0 0 2 2 2 0 Ferrochelatase DUF4552 PF15089.1 ETS74112.1 - 0.16 10.8 0.3 0.24 10.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Aminotran_1_2 PF00155.16 ETS74113.1 - 3.5e-36 124.9 0.0 5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 ETS74114.1 - 6.2e-56 188.5 0.6 6.2e-56 188.5 0.4 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 ETS74114.1 - 4.5e-13 49.4 0.0 9.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 ETS74114.1 - 0.019 15.5 0.9 0.082 13.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS74114.1 - 0.023 14.4 0.1 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS74114.1 - 0.054 13.4 0.4 0.23 11.4 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS74114.1 - 0.062 13.1 1.5 0.16 11.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS74114.1 - 0.24 11.9 0.2 0.24 11.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 ETS74115.1 - 1.7e-62 211.2 0.0 7e-43 146.7 0.0 2.9 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 ETS74115.1 - 9.3e-08 32.4 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74115.1 - 3.7e-07 30.6 0.0 9.8e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74115.1 - 8.3e-07 29.4 0.0 9.1e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74115.1 - 1.5e-06 28.0 0.0 5.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS74115.1 - 4.3e-05 23.8 0.0 0.00015 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74115.1 - 0.00031 20.3 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 ETS74115.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 ETS74115.1 - 0.029 13.4 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 ETS74115.1 - 0.096 11.3 0.1 0.23 10.0 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) FAM176 PF14851.1 ETS74115.1 - 7.3 6.2 8.7 8.3 6.0 4.2 2.1 2 0 0 2 2 2 0 FAM176 family MFS_1 PF07690.11 ETS74116.1 - 7.3e-16 57.8 48.3 7.3e-16 57.8 33.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-C2H2 PF00096.21 ETS74117.1 - 2.7e-10 39.9 14.5 9.5e-05 22.5 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS74117.1 - 9.3e-08 32.0 11.5 9.5e-07 28.8 0.9 2.8 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS74117.1 - 1.2e-07 31.5 8.7 0.00019 21.5 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS74117.1 - 0.0014 18.7 4.0 0.19 11.9 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding BolA PF01722.13 ETS74117.1 - 0.0017 18.2 0.9 1.6 8.7 0.1 2.3 1 1 1 2 2 2 2 BolA-like protein zf-H2C2_5 PF13909.1 ETS74117.1 - 0.01 15.9 8.7 0.058 13.6 2.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 ETS74117.1 - 0.055 13.3 6.2 2.4 8.1 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Bunya_G2 PF03563.8 ETS74117.1 - 0.3 9.9 0.8 0.43 9.4 0.6 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-met PF12874.2 ETS74117.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.9 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 ETS74117.1 - 0.43 10.3 9.3 3.4 7.4 1.9 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.10 ETS74117.1 - 0.93 9.2 6.7 0.71 9.6 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger Malate_synthase PF01274.17 ETS74118.1 - 1.2e-233 775.9 0.0 1.3e-233 775.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 ETS74118.1 - 0.057 12.2 0.0 0.11 11.2 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Lyase_1 PF00206.15 ETS74119.1 - 2.8e-113 378.2 0.1 3.7e-113 377.8 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 ETS74119.1 - 9.5e-23 80.0 0.0 2.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 ETS74119.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Peptidase_C2 PF00648.16 ETS74120.1 - 9.4e-11 41.2 0.0 2.6e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_C1 PF00112.18 ETS74120.1 - 0.0064 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Papain family cysteine protease p450 PF00067.17 ETS74121.1 - 9.6e-09 34.2 0.0 1.1e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS74122.1 - 1.1e-11 44.0 0.0 1.2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 ETS74124.1 - 3e-10 40.3 2.7 4.3e-10 39.8 1.9 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74124.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_racemase PF05544.6 ETS74125.1 - 3.4e-59 200.2 0.0 4.4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.13 ETS74126.1 - 2.8e-17 62.4 0.6 5.7e-17 61.4 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74126.1 - 1e-07 31.6 14.2 2.1e-07 30.7 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS74127.1 - 7.9e-29 100.4 31.8 7.9e-29 100.4 22.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS74127.1 - 1.1 9.2 11.1 0.25 11.3 1.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) DSBA PF01323.15 ETS74128.1 - 1.1e-26 93.5 0.0 1.3e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FMO-like PF00743.14 ETS74129.1 - 7.8e-26 90.3 0.0 9.4e-14 50.4 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS74129.1 - 2.5e-10 40.7 0.0 7.4e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS74129.1 - 2.4e-06 26.7 0.0 9.6e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS74129.1 - 1.4e-05 25.1 0.0 0.0001 22.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF2530 PF10745.4 ETS74129.1 - 0.074 13.0 0.2 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MFS_1 PF07690.11 ETS74130.1 - 8e-37 126.7 31.4 1.9e-35 122.2 23.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74130.1 - 6.7e-07 28.2 30.0 5.4e-06 25.2 15.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1228 PF06779.9 ETS74130.1 - 1e-05 25.4 4.1 0.0089 16.0 0.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) ESSS PF10183.4 ETS74130.1 - 0.081 13.3 0.1 0.33 11.3 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 2OG-FeII_Oxy PF03171.15 ETS74131.1 - 1.9e-12 47.3 0.0 4.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS74131.1 - 8.5e-08 32.7 1.0 1.1e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal MR_MLE_N PF02746.11 ETS74132.1 - 8.7e-14 51.5 0.0 2.3e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.1 ETS74132.1 - 2e-13 50.2 0.1 4.6e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS74132.1 - 9.4e-09 35.6 0.3 9.4e-09 35.6 0.2 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DC_STAMP PF07782.8 ETS74132.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 DC-STAMP-like protein Aldolase_II PF00596.16 ETS74133.1 - 1.3e-23 83.5 0.1 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldolase_II PF00596.16 ETS74134.1 - 6.5e-18 64.9 0.0 7.4e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aa_trans PF01490.13 ETS74135.1 - 2.8e-35 121.6 35.2 3.3e-35 121.3 24.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein OCD_Mu_crystall PF02423.10 ETS74136.1 - 1e-10 40.9 0.0 3.6e-09 35.8 0.0 2.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 ETS74136.1 - 4.8e-06 26.7 0.0 3.6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 ETS74136.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TMF_DNA_bd PF12329.3 ETS74136.1 - 0.12 12.2 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TruB_C PF09142.6 ETS74136.1 - 0.12 11.9 0.5 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal DUF521 PF04412.8 ETS74137.1 - 1.3e-130 435.5 0.0 1.7e-130 435.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 ETS74137.1 - 1.4e-28 98.3 0.3 3e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF126 Fungal_trans PF04082.13 ETS74138.1 - 5.8e-13 48.3 0.2 1.3e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_114 PF03537.8 ETS74139.1 - 1.8e-08 34.0 0.0 3.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 FAD_binding_2 PF00890.19 ETS74140.1 - 5.2e-73 246.2 0.0 6.9e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS74140.1 - 1.2e-08 34.4 0.0 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 ETS74140.1 - 1.5e-06 27.4 0.2 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS74140.1 - 6e-05 23.0 0.0 0.0006 19.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS74140.1 - 0.00031 20.7 0.4 0.00031 20.7 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS74140.1 - 0.00037 19.1 0.0 0.00062 18.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 ETS74140.1 - 0.0004 19.3 1.9 0.014 14.3 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 ETS74140.1 - 0.02 13.9 5.8 0.027 13.5 1.4 2.6 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.14 ETS74140.1 - 0.09 11.8 0.6 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain ERG2_Sigma1R PF04622.7 ETS74141.1 - 9.6e-90 299.5 1.5 1.1e-89 299.4 1.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein IBV_3C PF03620.8 ETS74142.1 - 0.19 11.6 1.6 0.35 10.8 0.2 2.0 1 1 1 2 2 2 0 IBV 3C protein DUF2670 PF10875.3 ETS74142.1 - 1.2 9.1 3.7 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Ribosomal_60s PF00428.14 ETS74143.1 - 0.0085 16.4 0.3 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PhyH PF05721.8 ETS74144.1 - 2.4e-10 40.7 0.0 7.2e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 ETS74145.1 - 3.4e-07 29.1 0.5 4.8e-07 28.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74145.1 - 0.0014 18.4 9.2 0.0031 17.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS74146.1 - 3.9e-100 335.5 28.0 4.5e-100 335.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74146.1 - 8.4e-33 113.5 27.8 8.4e-33 113.5 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS74146.1 - 5.2e-08 31.5 0.9 7.4e-08 31.0 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Lig_chan PF00060.21 ETS74146.1 - 0.037 13.7 0.1 0.037 13.7 0.1 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel VQ PF05678.9 ETS74146.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 VQ motif COesterase PF00135.23 ETS74148.1 - 1.2e-72 245.3 0.0 1.7e-68 231.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS74148.1 - 4.4e-06 26.4 0.0 1.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zip PF02535.17 ETS74149.1 - 4.7e-50 170.3 0.1 5.5e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Methyltransf_11 PF08241.7 ETS74151.1 - 5.8e-08 33.1 0.0 9.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS74151.1 - 3.3e-05 23.1 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS74151.1 - 0.0019 18.5 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74151.1 - 0.011 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS74151.1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS74151.1 - 0.059 12.9 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Radical_SAM PF04055.16 ETS74152.1 - 4e-14 53.1 0.0 6.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF3367 PF11847.3 ETS74152.1 - 0.037 11.9 0.1 0.049 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) PhyH PF05721.8 ETS74154.1 - 1.2e-23 84.2 0.0 1.7e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_20 PF00728.17 ETS74157.1 - 1.4e-35 123.0 2.5 8e-35 120.6 1.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 ETS74157.1 - 8.6e-07 29.5 0.0 2.5e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Alpha_L_fucos PF01120.12 ETS74158.1 - 2.8e-75 253.3 1.0 3.9e-75 252.9 0.7 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Glyco_hydro_35 PF01301.14 ETS74159.1 - 3.5e-83 279.5 0.4 5e-83 279.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 ETS74159.1 - 6.4e-07 29.6 0.6 6.8e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Pmp3 PF01679.12 ETS74161.1 - 2.4e-12 46.3 5.7 3.2e-12 45.9 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L34e PF01199.13 ETS74161.1 - 0.0011 19.1 0.6 0.0016 18.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF4246 PF14033.1 ETS74162.1 - 2.1e-134 448.8 5.0 5.5e-134 447.5 3.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) DUF3000 PF11452.3 ETS74162.1 - 0.036 13.2 0.2 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) MFS_1 PF07690.11 ETS74163.1 - 4.8e-35 120.9 27.8 4.8e-35 120.9 19.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HupE_UreJ_2 PF13795.1 ETS74163.1 - 0.017 14.5 0.2 0.017 14.5 0.1 2.1 2 0 0 2 2 2 0 HupE / UreJ protein DUF485 PF04341.7 ETS74163.1 - 0.24 11.1 0.1 0.24 11.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function, DUF485 Aminotran_5 PF00266.14 ETS74164.1 - 2.5e-11 42.9 0.0 4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 ETS74164.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 ETS74165.1 - 4.1e-139 463.6 0.0 5.1e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 ETS74165.1 - 0.0033 15.9 0.0 0.1 11.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Fungal_trans PF04082.13 ETS74166.1 - 2e-13 49.7 0.3 5e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74166.1 - 4.7e-07 29.6 13.2 7.7e-07 28.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM196 PF15265.1 ETS74166.1 - 6.8 5.7 17.3 1.8 7.7 8.3 2.0 2 0 0 2 2 2 0 FAM196 family SSF PF00474.12 ETS74167.1 - 7.8e-21 74.1 32.9 7.8e-21 74.1 22.8 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family Bac_luciferase PF00296.15 ETS74168.1 - 6.9e-58 196.1 0.4 1.1e-57 195.5 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase CPSase_L_chain PF00289.17 ETS74168.1 - 0.02 14.9 0.0 0.065 13.3 0.0 1.8 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain PNP_UDP_1 PF01048.15 ETS74169.1 - 0.00025 20.0 0.0 0.00073 18.5 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily UbiA PF01040.13 ETS74170.1 - 7.9e-19 67.8 20.9 9.6e-19 67.6 13.8 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF754 PF05449.6 ETS74170.1 - 0.041 13.8 1.5 0.69 9.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF754) PAS_9 PF13426.1 ETS74171.1 - 1e-17 64.3 0.0 6e-14 52.2 0.0 2.7 2 0 0 2 2 2 2 PAS domain RGS PF00615.14 ETS74171.1 - 9.8e-13 48.2 0.0 2.8e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.5 ETS74171.1 - 0.053 13.5 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold PAS_3 PF08447.6 ETS74171.1 - 0.13 12.3 0.0 0.92 9.6 0.0 2.4 2 1 0 2 2 2 0 PAS fold DUF2263 PF10021.4 ETS74172.1 - 4.6e-18 65.6 0.0 9.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BPL_LplA_LipB PF03099.14 ETS74173.1 - 3.5e-09 36.7 0.0 1.3e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.4 ETS74174.1 - 7.4e-56 189.2 0.0 1.1e-55 188.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain FYDLN_acid PF09538.5 ETS74175.1 - 0.65 10.6 13.3 1.2 9.7 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 ETS74175.1 - 1.3 6.9 6.0 1.8 6.5 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETS74175.1 - 2.1 6.1 7.5 2.6 5.8 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_UL49_2 PF04823.7 ETS74176.1 - 0.15 12.0 1.4 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein Grp1_Fun34_YaaH PF01184.14 ETS74177.1 - 6.5e-29 100.7 18.2 8.6e-29 100.3 12.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BCHF PF07284.6 ETS74177.1 - 0.42 10.4 3.9 0.89 9.3 2.7 1.5 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) PCI PF01399.22 ETS74178.1 - 2e-17 63.4 0.7 5.7e-17 61.9 0.0 2.1 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 ETS74178.1 - 3.3e-06 26.9 0.1 8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 ETS74178.1 - 3.4e-05 23.3 0.3 0.09 12.6 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS74178.1 - 0.002 18.0 0.0 1.8 8.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS74178.1 - 0.007 15.9 0.3 0.23 11.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS74178.1 - 0.025 14.2 0.2 0.23 11.1 0.0 2.7 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 ETS74178.1 - 0.031 14.1 3.2 0.14 12.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS74178.1 - 0.44 10.5 4.3 3.1 7.8 0.0 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS74178.1 - 3.2 7.7 5.2 1.4 8.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.3 ETS74179.1 - 2.3e-25 88.8 3.6 2.3e-25 88.8 2.5 4.6 3 1 1 4 4 4 2 Pre-mRNA splicing factor Cir_N PF10197.4 ETS74179.1 - 2.2e-13 49.9 2.5 2.2e-13 49.9 1.7 3.5 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3328 PF11807.3 ETS74181.1 - 3.6e-22 79.1 4.9 2.2e-21 76.5 3.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Ras PF00071.17 ETS74182.1 - 4.6e-54 182.1 0.0 5.3e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS74182.1 - 3.4e-16 59.7 0.0 4.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS74182.1 - 3.4e-10 39.4 0.0 8e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS74182.1 - 3.1e-05 23.2 0.0 3.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS74182.1 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS74182.1 - 0.0029 16.8 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 ETS74182.1 - 0.011 14.4 0.0 0.027 13.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 ETS74182.1 - 0.038 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase GTP_EFTU PF00009.22 ETS74182.1 - 0.066 12.6 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETS74182.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Cu-oxidase_3 PF07732.10 ETS74183.1 - 1.4e-45 153.7 4.1 3.7e-42 142.7 0.2 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS74183.1 - 5.1e-33 113.5 8.6 2.5e-30 104.7 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS74183.1 - 3.1e-27 95.4 1.0 1.7e-26 93.0 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Romo1 PF10247.4 ETS74184.1 - 1.8e-24 85.7 13.7 2.5e-17 62.8 3.6 2.2 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 ETS74184.1 - 0.014 15.4 7.0 0.041 13.9 4.4 1.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 ETS74184.1 - 1.5 8.4 3.8 1.1 8.9 0.1 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain FHA PF00498.21 ETS74185.1 - 7.5e-18 64.4 0.0 2e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain IFT57 PF10498.4 ETS74185.1 - 6.7 5.3 10.4 4.4 5.9 2.3 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NACHT PF05729.7 ETS74186.1 - 0.009 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Peptidase_S9 PF00326.16 ETS74187.1 - 0.00036 19.8 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS74187.1 - 0.0012 18.8 0.1 0.0031 17.4 0.0 1.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74187.1 - 0.0016 18.2 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 ETS74188.1 - 1.2e-77 256.3 1.4 1.5e-19 70.0 0.1 7.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74188.1 - 1.8e-67 219.9 0.9 1e-07 31.4 0.1 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 ETS74188.1 - 2.1e-55 184.1 0.9 2.4e-11 43.8 0.1 9.1 4 3 6 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74188.1 - 2.1e-52 169.8 0.3 0.00013 21.8 0.1 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 ETS74188.1 - 3.3e-47 157.4 3.6 3.5e-10 39.7 0.0 10.7 3 2 7 11 11 11 8 Ankyrin repeats (many copies) AMNp_N PF10423.4 ETS74188.1 - 0.0033 17.0 0.0 2.8 7.5 0.0 3.3 3 1 1 4 4 4 2 Bacterial AMP nucleoside phosphorylase N-terminus Dioxygenase_C PF00775.16 ETS74190.1 - 9.5e-10 38.0 0.1 1.7e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase NACHT PF05729.7 ETS74191.1 - 5.4e-07 29.4 0.0 1.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS74191.1 - 1.2e-05 25.5 0.2 0.00079 19.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 ETS74191.1 - 0.0029 17.8 0.1 0.01 16.1 0.0 2.0 2 1 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 ETS74191.1 - 0.0037 16.1 0.1 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 ETS74191.1 - 0.0042 17.1 0.4 0.021 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS74191.1 - 0.0053 17.5 0.1 0.062 14.1 0.0 2.9 3 1 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 ETS74191.1 - 0.0056 16.4 0.1 0.033 13.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 ETS74191.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS74191.1 - 0.04 13.3 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 ETS74191.1 - 0.063 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS74191.1 - 0.07 13.4 3.0 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS74191.1 - 0.073 12.6 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS74191.1 - 0.11 12.7 0.1 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.2 ETS74192.1 - 1.9e-45 153.1 0.1 2.7e-20 72.4 0.0 6.7 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS74192.1 - 8.2e-39 131.3 6.5 1.6e-09 37.9 0.0 9.4 8 1 2 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.25 ETS74192.1 - 7.2e-29 98.1 9.1 1.2e-06 28.0 0.0 10.5 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.1 ETS74192.1 - 2e-25 86.2 1.8 0.00028 20.8 0.0 10.0 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 ETS74192.1 - 1.9e-23 81.9 6.3 0.015 15.5 0.0 9.6 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS74192.1 - 1.6e-14 53.4 0.1 3.3e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain ADH_zinc_N PF00107.21 ETS74193.1 - 1e-09 38.0 0.4 1.8e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS74193.1 - 1.2e-07 31.3 0.0 2.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pertus-S5-tox PF09276.5 ETS74194.1 - 0.13 12.2 0.1 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin S5 subunit COesterase PF00135.23 ETS74195.1 - 1e-71 242.3 3.0 4e-71 240.3 2.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS74195.1 - 0.0026 17.3 0.1 0.0083 15.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS74195.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family LysM PF01476.15 ETS74196.1 - 1.4e-06 28.0 0.0 0.00039 20.2 0.0 3.2 3 0 0 3 3 3 2 LysM domain ADH_zinc_N_2 PF13602.1 ETS74197.1 - 7.9e-21 75.2 0.3 1.8e-20 74.0 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS74197.1 - 9.1e-10 38.1 0.1 1.7e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS74197.1 - 1.4e-07 31.2 0.0 1.5e-06 27.9 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 ETS74197.1 - 0.019 14.5 0.2 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 ETS74197.1 - 0.042 13.4 1.9 0.051 13.1 0.4 1.6 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3812 PF12757.2 ETS74197.1 - 0.047 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) NAD_binding_10 PF13460.1 ETS74197.1 - 0.061 13.3 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding FdhE PF04216.7 ETS74198.1 - 0.083 12.5 3.8 0.13 11.9 2.4 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation MutS_III PF05192.13 ETS74198.1 - 0.094 12.4 2.7 0.13 12.0 1.9 1.3 1 0 0 1 1 1 0 MutS domain III DUF2207 PF09972.4 ETS74199.1 - 0.03 12.9 0.2 0.037 12.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.2 ETS74199.1 - 0.054 13.4 1.4 0.091 12.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) KLRAQ PF10205.4 ETS74199.1 - 0.077 13.0 1.9 0.11 12.5 0.4 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Tetraspannin PF00335.15 ETS74199.1 - 3.5 6.8 8.0 5.3 6.2 5.5 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1625 PF07787.7 ETS74199.1 - 7.2 5.7 7.2 6.7 5.8 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Tyrosinase PF00264.15 ETS74200.1 - 6.8e-42 144.1 3.4 1e-41 143.5 2.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HET PF06985.6 ETS74201.1 - 1.2e-22 80.5 5.7 1e-19 71.0 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Methyltransf_11 PF08241.7 ETS74202.1 - 9.4e-16 58.0 0.0 2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS74202.1 - 2.6e-11 43.8 0.0 4.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74202.1 - 2.8e-11 43.2 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74202.1 - 1.2e-09 38.6 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS74202.1 - 5.2e-09 36.3 0.0 8.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74202.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS74202.1 - 7.4e-05 21.9 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS74202.1 - 8e-05 22.6 0.2 0.00029 20.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS74202.1 - 0.003 16.9 0.0 0.0087 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 ETS74202.1 - 0.0041 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 ETS74202.1 - 0.066 12.2 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 ETS74202.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3491 PF11996.3 ETS74202.1 - 0.13 9.7 0.0 0.17 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) Pkinase PF00069.20 ETS74203.1 - 4.5e-12 45.6 0.0 9.4e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74203.1 - 3.7e-06 26.2 0.0 8.4e-06 25.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.17 ETS74204.1 - 2.4e-16 59.7 0.0 3.5e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family CorA PF01544.13 ETS74206.1 - 8.7e-13 47.9 4.0 1.8e-11 43.5 1.0 2.5 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Flu_M2 PF00599.12 ETS74206.1 - 0.036 13.8 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Influenza Matrix protein (M2) PMP22_Claudin PF00822.15 ETS74206.1 - 0.19 11.3 0.5 1.6 8.3 0.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family WD40 PF00400.27 ETS74210.1 - 1.7e-14 53.0 3.9 1.1e-05 25.1 0.0 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETS74210.1 - 0.00029 19.1 4.2 0.013 13.7 0.7 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 ETS74210.1 - 0.0078 15.7 0.7 0.11 11.9 0.4 2.5 1 1 0 1 1 1 1 PQQ-like domain Big_2 PF02368.13 ETS74210.1 - 0.033 14.0 0.6 0.097 12.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Pro-kuma_activ PF09286.6 ETS74211.1 - 1.8e-48 164.2 0.8 2.9e-48 163.5 0.5 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS74211.1 - 3e-08 33.1 3.1 4.8e-08 32.4 2.1 1.2 1 0 0 1 1 1 1 Subtilase family Zn_peptidase PF04228.8 ETS74212.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase TRI12 PF06609.8 ETS74213.1 - 1.7e-80 270.9 23.4 2.2e-80 270.5 16.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS74213.1 - 1.5e-22 79.8 51.4 1.2e-21 76.7 34.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74213.1 - 6.9e-11 41.3 11.8 6.9e-11 41.3 8.1 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter Mid2 PF04478.7 ETS74215.1 - 1.6e-06 27.6 3.3 1.6e-06 27.6 2.3 2.9 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 ETS74215.1 - 0.00077 18.7 0.2 0.00077 18.7 0.1 2.9 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 ETS74215.1 - 0.31 10.5 1.3 0.78 9.2 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TFIIA PF03153.8 ETS74215.1 - 0.5 10.2 10.4 0.62 9.8 7.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETS74215.1 - 2 6.5 21.2 2.3 6.4 14.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 ETS74215.1 - 6.8 4.3 17.2 9.1 3.8 11.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CTP_transf_2 PF01467.21 ETS74217.1 - 0.00019 21.5 0.1 0.0022 18.0 0.1 2.5 3 0 0 3 3 3 1 Cytidylyltransferase TraH_2 PF06871.6 ETS74217.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 TraH_2 Amidohydro_1 PF01979.15 ETS74218.1 - 4e-25 89.1 0.0 6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS74218.1 - 1.5e-13 50.3 0.0 6.6e-13 48.2 0.0 2.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS74218.1 - 2.8e-10 40.6 1.7 5.9e-08 33.0 1.2 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS74218.1 - 1.7e-08 34.0 0.3 2.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Cerato-platanin PF07249.7 ETS74219.1 - 8.1e-55 183.9 5.4 9.5e-55 183.7 3.7 1.0 1 0 0 1 1 1 1 Cerato-platanin Bundlin PF05307.6 ETS74219.1 - 3.8 7.4 5.5 25 4.8 3.5 2.3 1 1 0 1 1 1 0 Bundlin M20_dimer PF07687.9 ETS74220.1 - 1.1e-09 38.0 0.1 2.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 ETS74220.1 - 1.8e-06 27.5 2.6 2.9e-06 26.9 1.7 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 ETS74221.1 - 2.4e-38 131.7 32.3 2.9e-38 131.4 22.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Baculo_PEP_C PF04513.7 ETS74222.1 - 0.015 15.1 0.7 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M36 PF02128.10 ETS74223.1 - 2.9e-155 516.7 6.1 3.8e-155 516.3 4.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 ETS74223.1 - 1.7e-11 43.4 1.9 1e-10 40.8 1.8 2.0 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 ETS74223.1 - 0.0091 16.0 0.5 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M4_C PF02868.10 ETS74223.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M50B PF13398.1 ETS74223.1 - 0.2 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like IF-2B PF01008.12 ETS74224.1 - 3e-26 92.0 0.0 5.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 ETS74224.1 - 3.4e-08 33.1 0.0 5.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2450 PF10475.4 ETS74224.1 - 0.048 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Fungal_trans PF04082.13 ETS74225.1 - 3e-12 45.9 0.0 6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74225.1 - 1.2e-06 28.2 9.7 1.2e-06 28.2 6.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprT-like PF10263.4 ETS74226.1 - 0.0013 18.4 0.1 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 SprT-like family ABC_tran PF00005.22 ETS74227.1 - 1.5e-47 161.2 0.2 3.8e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 ETS74227.1 - 6.9e-23 81.2 41.7 2.6e-14 53.0 16.1 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 ETS74227.1 - 4.2e-20 72.9 2.0 7.8e-05 22.7 0.0 4.6 4 1 1 5 5 5 4 AAA domain AAA_29 PF13555.1 ETS74227.1 - 1.2e-08 34.2 3.2 0.0011 18.4 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 ETS74227.1 - 2.1e-06 27.1 3.0 0.43 9.7 0.2 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS74227.1 - 8.3e-06 26.2 4.1 0.045 14.0 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS74227.1 - 9.5e-05 22.4 0.8 0.46 10.4 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane PF01061.19 ETS74227.1 - 0.0014 17.7 15.1 0.0014 17.7 10.4 4.3 3 2 0 3 3 3 1 ABC-2 type transporter DUF258 PF03193.11 ETS74227.1 - 0.0024 17.0 0.8 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 ETS74227.1 - 0.0032 16.5 0.0 3.9 6.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 ETS74227.1 - 0.015 14.6 0.2 2.8 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS74227.1 - 0.025 14.1 1.0 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ETS74227.1 - 0.03 13.1 1.1 0.22 10.2 0.1 2.2 2 0 0 2 2 2 0 ArgK protein SRP54 PF00448.17 ETS74227.1 - 0.09 12.2 0.3 12 5.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 ETS74227.1 - 0.12 12.4 0.8 22 5.1 0.2 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS74227.1 - 0.16 11.0 0.9 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 ETS74227.1 - 0.26 11.0 3.7 14 5.5 0.0 3.8 4 0 0 4 4 3 0 Part of AAA domain G-alpha PF00503.15 ETS74227.1 - 0.48 9.0 0.0 3.3 6.3 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 ETS74227.1 - 0.95 9.3 2.8 29 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 ETS74227.1 - 1.2 8.8 3.4 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 FAM176 PF14851.1 ETS74227.1 - 1.8 8.2 5.0 26 4.4 0.0 2.6 2 0 0 2 2 2 0 FAM176 family T4SS PF07996.6 ETS74228.1 - 0.0022 17.8 0.6 0.0039 17.0 0.4 1.4 1 0 0 1 1 1 1 Type IV secretion system proteins HemX PF04375.9 ETS74228.1 - 0.038 12.5 3.0 0.057 11.9 2.1 1.2 1 0 0 1 1 1 0 HemX rve_3 PF13683.1 ETS74228.1 - 0.12 11.8 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain IncA PF04156.9 ETS74228.1 - 0.14 11.7 4.9 0.23 11.0 3.4 1.3 1 0 0 1 1 1 0 IncA protein OEP PF02321.13 ETS74228.1 - 0.18 11.3 9.5 0.27 10.8 6.6 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein T2SM PF04612.7 ETS74228.1 - 0.2 11.4 4.9 0.43 10.3 3.4 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Synaphin PF05835.7 ETS74228.1 - 0.22 11.6 3.0 0.37 10.9 2.1 1.3 1 0 0 1 1 1 0 Synaphin protein DUF4398 PF14346.1 ETS74228.1 - 0.3 11.1 8.1 0.44 10.6 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) CENP-Q PF13094.1 ETS74228.1 - 0.47 10.4 9.2 0.23 11.4 3.9 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Rad4 PF03835.10 ETS74229.1 - 1.1e-30 105.9 0.1 2.8e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 ETS74229.1 - 1.6e-22 79.0 0.0 3.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 ETS74229.1 - 3.6e-20 71.2 0.0 1.2e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 ETS74229.1 - 1.6e-09 37.9 0.0 6.8e-09 35.9 0.0 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 ETS74229.1 - 0.0023 18.1 0.3 0.0023 18.1 0.2 3.5 3 1 0 3 3 3 1 Transglutaminase-like superfamily Amidohydro_2 PF04909.9 ETS74230.1 - 1.2e-08 34.8 0.0 5.3e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS74230.1 - 4.5e-08 33.4 0.5 6.3e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.1 ETS74230.1 - 0.033 14.3 0.1 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 CoA binding domain HMG_CoA_synt_C PF08540.5 ETS74231.1 - 1.4e-101 339.6 0.3 2e-101 339.2 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 ETS74231.1 - 7.2e-92 305.6 0.6 1.1e-91 305.1 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Peptidase_C41 PF05417.6 ETS74231.1 - 0.11 12.0 0.1 52 3.3 0.0 3.1 3 0 0 3 3 3 0 Hepatitis E cysteine protease RRM_1 PF00076.17 ETS74232.1 - 4.1e-19 67.9 0.1 3e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS74232.1 - 1.8e-15 56.6 0.0 2.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS74232.1 - 5.5e-10 38.9 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PXA PF02194.10 ETS74233.1 - 4e-54 183.0 0.4 4e-54 183.0 0.2 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 ETS74233.1 - 1.9e-29 102.0 0.1 8.2e-29 99.9 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 ETS74233.1 - 8e-21 73.9 0.6 2.1e-20 72.6 0.4 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 ETS74233.1 - 1.4e-11 44.5 0.2 1.8e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain AA_permease_2 PF13520.1 ETS74234.1 - 3.2e-42 144.5 56.0 4e-42 144.2 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS74234.1 - 5.3e-27 94.2 52.6 6.4e-27 94.0 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease Methyltransf_4 PF02390.12 ETS74235.1 - 1.9e-53 180.4 0.0 2.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS74235.1 - 0.00066 20.2 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS74235.1 - 0.0029 17.6 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS74235.1 - 0.0041 17.4 0.1 0.02 15.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74235.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74235.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74235.1 - 0.021 15.3 0.0 0.22 12.0 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 ETS74235.1 - 0.021 13.7 0.0 0.051 12.5 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 ETS74235.1 - 0.035 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS74235.1 - 0.04 14.3 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain MTS PF05175.9 ETS74235.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 ETS74235.1 - 0.043 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pex14_N PF04695.8 ETS74236.1 - 1.6e-39 135.0 0.0 1.6e-39 135.0 0.0 2.9 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 ETS74236.1 - 2.3e-05 24.5 1.5 4.7e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein DUF1241 PF06840.6 ETS74236.1 - 0.0029 16.8 1.4 0.0046 16.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinesin-relat_1 PF12711.2 ETS74236.1 - 0.0057 17.0 0.4 0.014 15.7 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor DUF3584 PF12128.3 ETS74236.1 - 0.028 11.7 6.5 0.037 11.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 ETS74236.1 - 0.11 12.1 6.2 0.18 11.3 4.3 1.4 1 0 0 1 1 1 0 IncA protein Nup88 PF10168.4 ETS74236.1 - 0.26 9.0 2.5 0.35 8.6 1.8 1.1 1 0 0 1 1 1 0 Nuclear pore component Sipho_Gp157 PF05565.6 ETS74236.1 - 1.1 8.8 9.1 1.9 8.0 3.9 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 Orbi_VP5 PF00901.12 ETS74236.1 - 6.6 4.8 6.6 9.3 4.3 4.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Abhydrolase_3 PF07859.8 ETS74237.1 - 9.6e-37 126.5 0.0 2.5e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS74237.1 - 0.0016 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS74237.1 - 0.0019 17.9 0.0 0.0053 16.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3298 PF11738.3 ETS74237.1 - 0.14 12.6 0.1 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) FAD_binding_4 PF01565.18 ETS74238.1 - 6.2e-16 58.1 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyrid_oxidase_2 PF13883.1 ETS74239.1 - 1.7e-41 141.8 0.0 2.8e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase WSC PF01822.14 ETS74240.1 - 2.2e-13 49.9 6.3 4.1e-13 49.0 4.4 1.5 1 0 0 1 1 1 1 WSC domain DUF1517 PF07466.6 ETS74240.1 - 0.03 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) GATA PF00320.22 ETS74241.1 - 1.7e-16 59.2 1.9 3.3e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 ETS74241.1 - 2.4e-12 46.1 1.0 4.3e-12 45.3 0.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.3 ETS74242.1 - 2.8e-33 115.0 2.0 5.8e-33 114.0 1.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74242.1 - 2.9e-07 30.2 9.5 4.5e-07 29.6 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imp-YgjV PF10688.4 ETS74242.1 - 0.086 12.2 0.2 12 5.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial inner membrane protein MFS_1 PF07690.11 ETS74243.1 - 6.6e-32 110.5 54.6 3.4e-30 104.9 37.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TFR_dimer PF04253.10 ETS74244.1 - 1.9e-18 66.2 0.0 3e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS74244.1 - 3.4e-17 62.7 0.0 6.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS74244.1 - 5e-05 22.9 0.1 0.0002 21.0 0.0 2.0 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 ETS74244.1 - 0.0078 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 ETS74244.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 GTF2I PF02946.9 ETS74245.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 GTF2I-like repeat RRM_1 PF00076.17 ETS74245.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTX_C PF08339.5 ETS74247.1 - 0.12 12.0 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 RTX C-terminal domain DUF202 PF02656.10 ETS74249.1 - 0.28 11.4 21.2 2 8.7 0.3 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) PhoD PF09423.5 ETS74250.1 - 5.9e-148 493.1 6.7 6.9e-148 492.9 4.6 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Citrate_synt PF00285.16 ETS74251.1 - 1.1e-113 379.5 0.0 1.5e-113 379.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Ctr PF04145.10 ETS74257.1 - 2.3e-29 102.2 0.1 2.9e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.13 ETS74258.1 - 2.6e-23 80.9 0.4 3.8e-23 80.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 ETS74258.1 - 0.13 11.5 0.1 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Tetraspannin PF00335.15 ETS74259.1 - 4.7e-05 22.7 5.9 0.00027 20.2 4.1 2.0 1 1 0 1 1 1 1 Tetraspanin family adh_short PF00106.20 ETS74260.1 - 2.1e-08 34.2 1.1 2.6e-06 27.4 0.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74260.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74260.1 - 0.0017 18.0 0.2 0.0042 16.7 0.0 1.7 2 0 0 2 2 2 1 KR domain PTCB-BRCT PF12738.2 ETS74261.1 - 5.4e-11 42.1 0.0 9.4e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 ETS74261.1 - 4.9e-10 39.4 0.0 9.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 ETS74261.1 - 0.0014 18.3 0.3 0.0039 16.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.16 ETS74261.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain CTC1 PF15489.1 ETS74262.1 - 0.0064 13.9 0.0 0.0087 13.4 0.0 1.1 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 eIF-1a PF01176.14 ETS74263.1 - 2.1e-27 94.2 0.1 3e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DAGK_acc PF00609.14 ETS74263.1 - 0.056 13.5 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain WH1 PF00568.18 ETS74264.1 - 1e-27 96.0 0.1 1.4e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 ETS74264.1 - 0.0021 17.5 0.3 0.0049 16.4 0.2 1.6 1 0 0 1 1 1 1 WH2 motif DUF2076 PF09849.4 ETS74264.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 3.3 4 1 1 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2076) ERCC4 PF02732.10 ETS74266.1 - 2.1e-25 89.1 0.0 4.5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Glycoprotein_B PF00606.13 ETS74267.1 - 0.028 12.4 1.5 0.029 12.3 1.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Zn_ribbon_recom PF13408.1 ETS74267.1 - 0.11 12.7 1.8 0.15 12.2 1.2 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain CN_hydrolase PF00795.17 ETS74268.1 - 9.1e-39 132.7 0.0 1.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NACHT PF05729.7 ETS74270.1 - 3.7e-08 33.2 0.1 1.1e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS74270.1 - 0.00014 22.0 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.1 ETS74270.1 - 0.00016 21.7 0.0 0.0023 18.1 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS74270.1 - 0.00021 21.5 0.0 0.00093 19.4 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.1 ETS74270.1 - 0.00021 21.3 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.1 ETS74270.1 - 0.00038 20.8 0.2 0.025 15.0 0.0 3.0 2 1 1 3 3 2 1 Ankyrin repeats (many copies) AAA_10 PF12846.2 ETS74270.1 - 0.00083 18.8 0.5 0.0097 15.3 0.0 3.0 3 1 0 3 3 2 1 AAA-like domain Abhydrolase_6 PF12697.2 ETS74270.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_helicase PF00910.17 ETS74270.1 - 0.018 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 ETS74270.1 - 0.023 14.6 0.0 0.22 11.4 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ank PF00023.25 ETS74270.1 - 0.03 14.1 0.6 0.46 10.3 0.0 3.4 3 0 0 3 3 2 0 Ankyrin repeat AAA_30 PF13604.1 ETS74270.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS74270.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 ETS74270.1 - 0.078 13.2 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 ETS74270.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS74270.1 - 0.1 11.4 0.2 0.28 9.9 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 ETS74270.1 - 0.11 11.8 0.0 0.34 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS74270.1 - 0.12 13.2 0.0 0.67 10.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS74270.1 - 0.15 12.2 0.0 0.68 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.9 ETS74270.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_19 PF13245.1 ETS74270.1 - 0.22 11.2 0.0 0.51 10.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 ETS74270.1 - 5 7.3 7.6 0.3 11.3 0.4 2.5 2 1 1 3 3 3 0 AAA domain Sugar_tr PF00083.19 ETS74271.1 - 6.3e-104 348.0 19.7 8.4e-104 347.6 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74271.1 - 6.3e-27 94.2 42.8 1.7e-24 86.1 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 ETS74271.1 - 0.078 11.0 5.8 0.036 12.1 1.3 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Ricin_B_lectin PF00652.17 ETS74272.1 - 2.4e-14 53.4 1.6 1.6e-13 50.7 1.1 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 ETS74272.1 - 9.7e-08 32.3 1.0 8.4e-07 29.3 0.7 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like F-box-like_2 PF13013.1 ETS74273.1 - 0.0022 17.7 0.3 0.06 13.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like domain bZIP_1 PF00170.16 ETS74274.1 - 8.7e-11 41.6 4.0 2e-10 40.4 2.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS74274.1 - 6.3e-06 25.9 6.2 1.2e-05 25.0 4.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MFS_1 PF07690.11 ETS74275.1 - 2.9e-13 49.2 47.7 2.9e-13 49.2 33.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74275.1 - 7.3e-06 24.8 10.9 7.3e-06 24.8 7.5 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter DoxD PF04173.8 ETS74275.1 - 0.22 11.1 6.4 3.1 7.4 2.6 2.5 1 1 1 2 2 2 0 TQO small subunit DoxD WD40 PF00400.27 ETS74277.1 - 8.5e-48 158.6 21.1 6.7e-12 44.8 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 ETS74277.1 - 2.5e-06 27.3 5.7 0.1 12.3 0.9 3.8 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 ETS74277.1 - 0.8 7.4 3.9 2.8 5.6 0.5 2.1 2 0 0 2 2 2 0 IKI3 family GSDH PF07995.6 ETS74278.1 - 2.4e-05 23.5 2.5 5e-05 22.5 0.5 2.5 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 ETS74278.1 - 0.00039 20.2 0.3 3.5 7.7 0.0 4.2 3 1 1 4 4 4 2 NHL repeat SGL PF08450.7 ETS74278.1 - 0.0028 17.0 0.6 0.35 10.1 0.1 2.9 2 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 ETS74278.1 - 0.0042 16.8 0.0 0.79 9.5 0.0 2.9 2 0 0 2 2 2 1 Beta-propeller repeat PD40 PF07676.7 ETS74278.1 - 0.098 12.3 2.0 0.85 9.3 0.2 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DAO PF01266.19 ETS74279.1 - 3.5e-53 180.7 0.0 4.1e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS74279.1 - 1.7e-07 31.1 0.1 4.8e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS74279.1 - 1.3e-06 28.6 0.0 0.53 10.3 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS74279.1 - 1.8e-06 27.2 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS74279.1 - 0.00017 21.4 0.1 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS74279.1 - 0.00022 21.1 0.2 0.0038 17.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS74279.1 - 0.00023 21.4 0.0 0.062 13.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS74279.1 - 0.00068 18.2 0.0 0.51 8.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 ETS74279.1 - 0.00072 18.5 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 ETS74279.1 - 0.017 14.0 0.0 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 ETS74279.1 - 0.044 12.6 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Flavoprotein PF02441.14 ETS74282.1 - 1.5e-18 66.7 0.2 2.9e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein MR_MLE_C PF13378.1 ETS74283.1 - 1.1e-19 70.4 0.0 6.9e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS74283.1 - 4.1e-13 49.6 0.1 1.3e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 ETS74283.1 - 0.00046 20.1 0.1 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 ETS74283.1 - 0.0045 15.9 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF1772 PF08592.6 ETS74284.1 - 0.013 15.2 0.6 0.013 15.2 0.4 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) OpgC_C PF10129.4 ETS74284.1 - 0.044 12.4 1.1 0.046 12.4 0.7 1.1 1 0 0 1 1 1 0 OpgC protein zf-Nse PF11789.3 ETS74286.1 - 1e-18 66.5 0.4 1.8e-18 65.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 ETS74286.1 - 0.00016 21.3 1.9 0.00018 21.1 0.4 1.8 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 ETS74286.1 - 0.0025 17.7 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 ETS74286.1 - 0.019 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETS74286.1 - 0.027 14.2 0.6 0.052 13.3 0.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 ETS74286.1 - 0.063 12.8 0.6 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FtsK_SpoIIIE PF01580.13 ETS74286.1 - 0.1 12.0 5.9 0.17 11.3 3.8 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family zf-rbx1 PF12678.2 ETS74286.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS74286.1 - 0.12 12.2 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Miro PF08477.8 ETS74287.1 - 5.2e-35 120.5 0.0 1e-19 71.1 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 ETS74287.1 - 1.5e-33 114.4 0.0 3e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 ETS74287.1 - 1.9e-30 103.9 0.3 3.9e-30 102.9 0.1 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 ETS74287.1 - 4.9e-23 81.2 0.0 7.5e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 ETS74287.1 - 4.1e-08 33.2 0.5 0.00046 20.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 ETS74287.1 - 1.3e-07 31.6 0.0 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS74287.1 - 2.6e-07 30.6 0.6 0.12 12.1 0.0 3.4 2 1 1 3 3 3 2 Dynamin family EF-hand_1 PF00036.27 ETS74287.1 - 4.6e-07 28.6 3.6 0.0052 16.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETS74287.1 - 1.2e-06 27.9 4.2 0.013 15.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.1 ETS74287.1 - 6.8e-06 26.1 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain GTP_EFTU PF00009.22 ETS74287.1 - 8.1e-05 22.1 0.0 0.45 9.9 0.0 3.2 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 ETS74287.1 - 0.00046 19.3 5.2 0.16 11.3 1.1 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 ETS74287.1 - 0.00088 19.4 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS74287.1 - 0.0011 18.5 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arf PF00025.16 ETS74287.1 - 0.0013 18.0 0.0 0.27 10.4 0.0 2.7 2 2 0 2 2 2 1 ADP-ribosylation factor family MobB PF03205.9 ETS74287.1 - 0.0037 16.9 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 ETS74287.1 - 0.0077 15.8 3.7 0.23 11.1 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair AAA_24 PF13479.1 ETS74287.1 - 0.0079 15.7 0.0 0.035 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS74287.1 - 0.016 15.3 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 ETS74287.1 - 0.021 14.7 0.0 5 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 ETS74287.1 - 0.024 14.3 0.4 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.22 ETS74287.1 - 0.045 14.0 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 ETS74287.1 - 0.064 12.4 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 ETS74287.1 - 0.071 12.1 0.0 0.4 9.6 0.0 1.9 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 ETS74287.1 - 0.096 12.2 0.1 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 ETS74287.1 - 0.11 12.1 0.0 8.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 ETS74287.1 - 0.11 11.3 0.1 1 8.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 ETS74287.1 - 0.16 11.3 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 ETS74288.1 - 6e-19 67.1 11.1 7.4e-06 25.6 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETS74288.1 - 0.013 15.2 0.0 0.076 12.7 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A ECR1_N PF14382.1 ETS74288.1 - 0.043 13.1 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Cytochrom_D1 PF02239.11 ETS74288.1 - 0.046 12.0 0.0 0.072 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arrestin_C PF02752.17 ETS74289.1 - 1.6e-20 73.6 0.1 1.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS74289.1 - 2.5e-17 63.0 0.0 1.4e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 ETS74289.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 ETS74290.1 - 3.4e-05 23.9 0.0 6.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PH domain MxiH PF09392.5 ETS74290.1 - 1.9 9.0 6.2 16 6.1 0.0 3.3 2 1 1 3 3 3 0 Type III secretion needle MxiH like DUF3836 PF12930.2 ETS74291.1 - 0.16 11.4 1.7 0.19 11.2 0.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF3836) Pkinase PF00069.20 ETS74292.1 - 8.5e-27 93.9 0.0 1e-19 70.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74292.1 - 0.00012 21.2 0.0 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LANC_like PF05147.8 ETS74293.1 - 1.6e-18 66.4 0.0 2.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein ABC_tran PF00005.22 ETS74294.1 - 1.8e-48 164.3 1.1 5.8e-23 81.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 ETS74294.1 - 5.6e-19 67.7 6.3 5.6e-19 67.7 4.4 4.0 4 1 2 6 6 3 1 ABC transporter AAA_21 PF13304.1 ETS74294.1 - 6.8e-18 65.6 0.3 0.00032 20.7 0.0 4.7 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 ETS74294.1 - 9.1e-11 41.3 3.7 0.0029 16.8 0.0 4.6 5 0 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 ETS74294.1 - 2.7e-09 37.8 0.2 0.0048 17.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 ETS74294.1 - 4.1e-07 29.3 0.1 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS74294.1 - 4.4e-07 29.3 0.1 0.0092 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 ETS74294.1 - 1.3e-06 27.7 4.9 0.32 9.9 0.0 4.9 5 1 0 5 5 5 2 AAA ATPase domain MMR_HSR1 PF01926.18 ETS74294.1 - 1.6e-06 28.0 0.0 0.013 15.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 ETS74294.1 - 2.1e-06 28.2 0.0 0.016 15.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 ETS74294.1 - 1.8e-05 25.0 5.2 0.045 14.0 0.0 3.7 5 0 0 5 5 2 2 AAA domain AAA_16 PF13191.1 ETS74294.1 - 2.5e-05 24.3 2.1 0.024 14.6 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS74294.1 - 2.5e-05 24.4 0.2 0.3 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 ETS74294.1 - 2.9e-05 23.7 0.1 0.14 11.8 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS74294.1 - 6e-05 23.2 0.0 0.16 12.1 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETS74294.1 - 9e-05 22.3 0.1 0.66 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS74294.1 - 0.00012 22.4 18.5 0.006 16.9 0.0 4.7 5 0 0 5 5 5 2 AAA domain ArgK PF03308.11 ETS74294.1 - 0.00017 20.4 0.7 0.38 9.4 0.0 2.8 3 0 0 3 3 2 2 ArgK protein ATP-synt_ab PF00006.20 ETS74294.1 - 0.00019 20.9 0.1 0.042 13.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 ETS74294.1 - 0.00039 20.0 0.1 0.55 9.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 ETS74294.1 - 0.00042 20.3 3.8 0.08 12.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 ETS74294.1 - 0.00069 19.4 0.5 0.58 10.1 0.2 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 ETS74294.1 - 0.001 18.9 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 ETS74294.1 - 0.0011 18.7 0.1 0.24 11.1 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_10 PF12846.2 ETS74294.1 - 0.0021 17.5 0.1 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 ETS74294.1 - 0.0028 17.0 0.2 1.5 8.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS74294.1 - 0.0041 17.2 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 ETS74294.1 - 0.005 15.9 0.8 0.17 10.9 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.14 ETS74294.1 - 0.0092 15.4 0.7 1.5 8.2 0.5 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 ETS74294.1 - 0.014 14.2 0.1 5.2 5.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 ETS74294.1 - 0.02 14.6 0.5 3 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 ETS74294.1 - 0.044 12.6 0.0 0.64 8.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 ETS74294.1 - 0.076 12.5 0.1 14 5.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 ETS74294.1 - 0.14 11.5 1.8 4.5 6.6 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS74294.1 - 0.2 11.4 8.9 0.94 9.2 0.0 4.1 4 1 0 4 4 4 0 Dynamin family Tubulin PF00091.20 ETS74296.1 - 3.6e-70 236.1 0.0 6.3e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS74296.1 - 3e-49 166.2 0.1 5.1e-49 165.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS74296.1 - 8.3e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETS74296.1 - 0.0037 16.7 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain NIR_SIR PF01077.17 ETS74297.1 - 3.6e-30 104.4 0.0 6.8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 ETS74297.1 - 1e-26 94.0 0.0 4.6e-26 91.9 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS74297.1 - 2.3e-18 66.3 1.9 1.9e-16 60.2 0.3 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 ETS74297.1 - 1.5e-14 53.7 4.4 3.3e-12 46.2 2.4 3.1 3 0 0 3 3 3 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 ETS74297.1 - 6.8e-13 48.2 0.0 3.9e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Rieske PF00355.21 ETS74297.1 - 7.8e-11 41.3 0.8 3.2e-10 39.4 0.2 2.4 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 ETS74297.1 - 5.6e-10 38.7 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 ETS74297.1 - 7.3e-10 39.2 0.0 3.6e-05 23.9 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS74297.1 - 0.00074 19.3 1.2 4.3 7.0 0.0 3.9 2 2 2 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 ETS74297.1 - 0.002 17.3 0.1 0.19 10.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 ETS74297.1 - 0.11 11.4 0.0 0.28 10.0 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) SUI1 PF01253.17 ETS74298.1 - 1.5e-13 50.3 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 adh_short PF00106.20 ETS74299.1 - 3.6e-30 105.0 0.6 5.8e-30 104.3 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74299.1 - 3.7e-26 92.3 0.0 4.6e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74299.1 - 2.8e-10 40.1 0.6 8.5e-10 38.5 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 ETS74299.1 - 0.011 15.1 0.3 0.019 14.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS74299.1 - 0.18 11.7 3.8 0.6 10.0 2.7 1.8 1 1 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 ETS74300.1 - 9e-59 198.7 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74300.1 - 1.6e-31 109.3 0.0 2.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS74300.1 - 1.4e-05 24.1 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS74300.1 - 0.0052 16.5 1.9 0.0075 16.0 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS74300.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BCS1_N PF08740.6 ETS74301.1 - 2.8e-45 154.2 0.1 2.8e-45 154.2 0.0 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 ETS74301.1 - 3.3e-17 62.9 0.0 1.2e-08 35.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS74301.1 - 0.0012 18.5 0.0 0.006 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETS74301.1 - 0.0029 17.0 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS74301.1 - 0.0078 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS74301.1 - 0.0088 16.8 0.0 0.0088 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS74301.1 - 0.015 15.2 0.5 0.075 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 ETS74301.1 - 0.047 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS74301.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC FPN1 PF06963.7 ETS74302.1 - 6.1e-131 436.7 23.2 7.1e-131 436.5 16.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Suf PF05843.9 ETS74303.1 - 0.0027 17.5 11.1 0.0029 17.3 7.7 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF1675 PF07897.6 ETS74303.1 - 0.1 12.4 6.6 0.11 12.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hid1 PF12722.2 ETS74303.1 - 0.91 7.1 7.3 0.94 7.0 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 ETS74303.1 - 1.9 5.4 9.5 2 5.2 6.6 1.0 1 0 0 1 1 1 0 Pathogenicity factor Macoilin PF09726.4 ETS74303.1 - 1.9 6.6 8.9 2.2 6.4 6.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 ETS74303.1 - 2.9 6.0 30.4 3.3 5.8 21.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 ETS74303.1 - 3.6 5.6 33.2 4.3 5.4 23.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4078 PF13300.1 ETS74305.1 - 1.7e-30 104.9 12.7 1.7e-30 104.9 8.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) THOC7 PF05615.8 ETS74305.1 - 0.4 10.9 12.4 9.8 6.4 6.0 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Homoserine_dh PF00742.14 ETS74306.1 - 5.9e-52 175.9 0.0 7.9e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 ETS74306.1 - 2.8e-18 66.4 0.0 5.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.16 ETS74306.1 - 0.022 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase ApbA PF02558.11 ETS74306.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 ETS74307.1 - 0.00012 22.0 0.1 0.0095 15.8 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS74307.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.11 ETS74308.1 - 2.4e-26 92.2 36.7 3e-26 91.9 25.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS74308.1 - 0.0086 15.8 0.3 0.0086 15.8 0.2 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF3487 PF11990.3 ETS74308.1 - 6.6 6.1 9.2 2 7.8 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) UCR_hinge PF02320.11 ETS74309.1 - 1.4e-27 95.3 7.1 1.4e-27 95.3 4.9 1.8 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 ETS74309.1 - 0.0021 16.1 15.8 0.0023 16.0 10.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Merozoite_SPAM PF07133.6 ETS74309.1 - 0.11 12.4 37.6 0.14 12.0 26.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.10 ETS74309.1 - 0.11 11.1 12.3 0.12 11.0 8.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 ETS74309.1 - 0.17 10.3 36.4 0.2 10.1 25.2 1.0 1 0 0 1 1 1 0 Daxx Family SRP-alpha_N PF04086.8 ETS74309.1 - 0.4 10.0 17.1 0.47 9.8 11.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MIP-T3 PF10243.4 ETS74309.1 - 0.44 8.9 30.6 0.54 8.6 21.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CKAP2_C PF15297.1 ETS74309.1 - 0.68 8.6 18.5 0.8 8.4 12.8 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Suf PF05843.9 ETS74309.1 - 1 9.0 6.3 1.2 8.8 4.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1510 PF07423.6 ETS74309.1 - 1.3 8.2 31.6 1.6 8.0 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 ETS74309.1 - 1.4 8.0 31.9 1.6 7.9 22.1 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS74309.1 - 1.7 6.4 34.9 1.9 6.3 24.2 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 ETS74309.1 - 1.7 8.6 24.1 2.3 8.2 16.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2413 PF10310.4 ETS74309.1 - 2.2 7.0 20.4 2.5 6.8 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 ETS74309.1 - 3 7.5 13.4 3.9 7.1 9.3 1.2 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.5 ETS74309.1 - 3.1 6.7 27.3 3.6 6.5 18.9 1.1 1 0 0 1 1 1 0 BUD22 Mitofilin PF09731.4 ETS74309.1 - 3.7 6.1 21.7 4 5.9 15.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4045 PF13254.1 ETS74309.1 - 4.1 6.5 16.9 4.8 6.3 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 ETS74309.1 - 4.6 6.2 15.2 5.1 6.1 10.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CENP-T PF15511.1 ETS74309.1 - 5.5 6.1 23.1 6.5 5.8 16.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 ETS74309.1 - 6.7 6.1 27.8 9 5.6 19.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 ETS74309.1 - 7.6 6.3 26.8 9.3 6.0 18.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 ETS74309.1 - 7.7 5.8 29.6 13 5.1 20.5 1.4 1 0 0 1 1 1 0 DDRGK domain RRN3 PF05327.6 ETS74309.1 - 7.8 4.4 15.6 8.9 4.2 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.7 ETS74309.1 - 8.9 4.9 10.3 11 4.6 7.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.1 ETS74309.1 - 9.6 4.6 13.2 11 4.3 9.2 1.1 1 0 0 1 1 1 0 Raftlin WWbp PF10349.4 ETS74310.1 - 3.9e-09 37.4 0.1 7.2e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Lipase_GDSL_2 PF13472.1 ETS74310.1 - 0.05 13.7 0.1 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GRAM PF02893.15 ETS74310.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Drf_GBD PF06371.8 ETS74311.1 - 7.6e-14 51.4 0.3 1.1e-12 47.7 0.2 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Actino_peptide PF14408.1 ETS74312.1 - 0.12 12.3 1.8 0.27 11.2 1.2 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Suc_Fer-like PF06999.7 ETS74313.1 - 6.2e-33 114.7 0.0 2.3e-28 99.8 0.0 2.3 2 0 0 2 2 2 2 Sucrase/ferredoxin-like Acyltransferase PF01553.16 ETS74314.1 - 3.1e-11 42.8 0.0 4e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase BRAP2 PF07576.7 ETS74315.1 - 1.9e-20 72.4 0.0 3.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 ETS74315.1 - 5.4e-19 68.0 3.5 1.6e-18 66.5 2.4 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 ETS74315.1 - 1.7e-10 40.5 10.1 1.7e-10 40.5 7.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 ETS74315.1 - 2e-06 27.3 7.5 5.9e-06 25.8 5.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS74315.1 - 2.5e-05 23.9 8.2 2.5e-05 23.9 5.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS74315.1 - 2.6e-05 24.1 9.1 2.6e-05 24.1 6.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS74315.1 - 3.5e-05 23.3 7.2 3.5e-05 23.3 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS74315.1 - 0.00096 18.8 4.6 0.0015 18.1 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETS74315.1 - 0.0015 18.6 5.3 0.0015 18.6 3.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger ApoO PF09769.4 ETS74315.1 - 0.08 12.6 0.5 0.18 11.5 0.2 1.7 1 1 1 2 2 2 0 Apolipoprotein O Baculo_RING PF05883.6 ETS74315.1 - 0.11 12.3 1.5 0.3 10.9 1.0 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 ETS74315.1 - 0.15 11.8 7.9 0.019 14.7 2.2 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 ETS74315.1 - 0.18 11.3 10.7 10 5.7 7.7 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 ETS74315.1 - 0.33 10.5 6.7 0.75 9.4 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prefoldin_2 PF01920.15 ETS74315.1 - 0.7 9.6 11.3 0.26 11.0 5.6 2.0 1 1 0 1 1 1 0 Prefoldin subunit DUF972 PF06156.8 ETS74315.1 - 1.3 9.4 12.8 2.1 8.7 3.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ERM PF00769.14 ETS74315.1 - 2.9 7.3 20.9 0.079 12.4 9.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 ETS74315.1 - 4.6 7.2 16.3 0.9 9.4 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 ETS74315.1 - 6 5.8 15.7 0.39 9.7 6.2 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 ubiquitin PF00240.18 ETS74316.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 ETS74316.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS74316.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETS74316.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETS74316.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETS74316.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETS74316.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 ETS74316.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 ETS74316.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 ETS74316.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 ETS74316.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 ETS74316.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 ETS74316.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 ETS74316.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 ETS74316.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 ETS74316.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 ETS74316.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 ETS74316.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 ETS74316.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 ETS74316.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 ETS74316.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Zn_clus PF00172.13 ETS74318.1 - 0.012 15.5 7.2 0.024 14.5 5.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 ETS74318.1 - 0.045 12.7 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Prenyltrans PF00432.16 ETS74319.1 - 2.4e-41 138.9 24.1 1.9e-09 36.8 0.2 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS74319.1 - 2.6e-23 82.5 0.0 5.5e-17 62.1 0.0 3.5 2 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS74319.1 - 1.7e-05 24.7 0.0 0.00031 20.7 0.0 2.6 2 1 0 2 2 2 1 Prenyltransferase-like DND1_DSRM PF14709.1 ETS74320.1 - 0.00037 20.7 0.1 0.00078 19.6 0.1 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 ETS74320.1 - 0.032 14.7 1.4 0.039 14.5 0.1 1.9 2 1 0 2 2 2 0 Double-stranded RNA binding motif NTP_transferase PF00483.18 ETS74321.1 - 1.1e-46 159.2 0.0 2.6e-46 157.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 ETS74321.1 - 1.8e-12 46.1 8.2 1.3e-09 37.1 1.1 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 ETS74321.1 - 2.4e-12 47.1 0.0 3.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 ETS74321.1 - 1.2e-06 27.9 2.5 1.2e-06 27.9 1.7 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 ETS74321.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FGGY_C PF02782.11 ETS74322.1 - 1.3e-71 240.3 0.2 2e-71 239.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETS74322.1 - 8.2e-65 218.5 0.0 1.1e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Collagen PF01391.13 ETS74322.1 - 0.092 12.3 3.3 0.23 11.0 2.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Nramp PF01566.13 ETS74324.1 - 1.3e-88 297.1 17.1 1.3e-88 297.1 11.9 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein PEMT PF04191.8 ETS74325.1 - 2.9e-33 114.1 2.6 2.9e-33 114.1 1.8 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.6 ETS74326.1 - 8.1e-34 116.5 0.0 8.1e-34 116.5 0.0 2.8 4 0 0 4 4 4 1 RXT2-like, N-terminal DUF4167 PF13763.1 ETS74326.1 - 0.07 13.1 0.3 0.07 13.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Gryzun PF07919.7 ETS74327.1 - 3.3e-92 309.5 0.1 4.1e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 ETS74327.1 - 3.2e-71 239.7 7.4 2.3e-67 227.0 5.1 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 HisG PF01634.13 ETS74327.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Gryzun-like PF12742.2 ETS74327.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Tyrosinase PF00264.15 ETS74328.1 - 4.2e-52 177.5 3.5 6.8e-52 176.8 2.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DHDPS PF00701.17 ETS74329.1 - 1.8e-39 135.0 0.0 2.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidase PF01425.16 ETS74330.1 - 4.1e-80 269.7 1.6 5.3e-80 269.4 1.1 1.1 1 0 0 1 1 1 1 Amidase GST_C_3 PF14497.1 ETS74332.1 - 1e-06 29.1 0.0 4.4e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS74332.1 - 0.001 18.8 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4565 PF15127.1 ETS74332.1 - 0.13 12.5 0.2 2.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4565) DUF3437 PF11919.3 ETS74333.1 - 3e-31 106.9 0.0 7.6e-31 105.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Glyco_hydro_6 PF01341.12 ETS74333.1 - 0.31 10.4 0.4 0.87 8.9 0.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolases family 6 DUF981 PF06168.6 ETS74334.1 - 0.05 13.3 0.1 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) MFS_1 PF07690.11 ETS74335.1 - 3.9e-21 75.1 53.5 2.4e-15 56.0 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans2 PF04188.8 ETS74337.1 - 1e-63 215.8 10.8 1.2e-63 215.5 7.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PMT_2 PF13231.1 ETS74337.1 - 1.5e-09 37.9 2.4 1.5e-09 37.9 1.6 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase 2OG-FeII_Oxy PF03171.15 ETS74338.1 - 2e-11 44.0 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS74338.1 - 9.1e-11 42.3 0.0 1.8e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UbiA PF01040.13 ETS74339.1 - 6.1e-23 81.3 13.8 8.8e-23 80.8 9.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 ETS74340.1 - 3.6e-52 177.4 0.0 4.6e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS74343.1 - 7.5e-29 100.6 0.1 1.4e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT_2 PF13279.1 ETS74344.1 - 0.027 14.8 0.1 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily PDR_CDR PF06422.7 ETS74345.1 - 0.86 9.2 4.2 0.48 10.1 0.4 2.5 2 1 0 2 2 2 0 CDR ABC transporter NMT1 PF09084.6 ETS74346.1 - 4.1e-11 42.8 0.1 5.5e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.7 ETS74346.1 - 0.00084 18.7 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.2 ETS74346.1 - 0.0009 18.6 0.4 0.0016 17.8 0.3 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 ETS74346.1 - 0.081 12.2 0.3 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 NMT1-like family NACHT PF05729.7 ETS74348.1 - 6.7e-09 35.6 0.3 1.7e-08 34.3 0.2 1.7 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETS74348.1 - 0.00049 19.0 0.0 0.045 12.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 ETS74348.1 - 0.00058 20.1 0.3 0.0043 17.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETS74348.1 - 0.00086 19.3 0.0 0.00086 19.3 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS74348.1 - 0.0012 18.9 4.7 0.0034 17.5 0.1 3.5 2 2 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETS74348.1 - 0.002 17.2 0.3 0.0061 15.5 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 ETS74348.1 - 0.0022 18.1 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 ETS74348.1 - 0.0026 17.2 0.1 0.0026 17.2 0.1 2.4 1 1 2 3 3 3 1 AAA-like domain AAA_23 PF13476.1 ETS74348.1 - 0.0062 16.8 0.2 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS74348.1 - 0.0079 16.3 0.5 0.58 10.3 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 ETS74348.1 - 0.0099 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS74348.1 - 0.011 16.5 0.0 0.13 13.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 ETS74348.1 - 0.012 15.4 0.2 0.1 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS74348.1 - 0.014 14.4 0.0 0.047 12.7 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 ETS74348.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 ETS74348.1 - 0.02 13.8 1.2 0.84 8.4 0.0 2.6 3 1 0 3 3 3 0 Type II/IV secretion system protein AAA_18 PF13238.1 ETS74348.1 - 0.02 15.2 0.0 0.071 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETS74348.1 - 0.021 14.3 0.7 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 ETS74348.1 - 0.027 13.8 0.0 0.34 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS74348.1 - 0.064 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETS74348.1 - 0.07 12.8 0.1 0.37 10.4 0.0 2.3 2 2 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 ETS74348.1 - 0.079 12.6 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 NTPase Acp26Ab PF05777.7 ETS74348.1 - 0.085 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Miro PF08477.8 ETS74348.1 - 0.095 13.2 0.6 0.25 11.8 0.0 2.1 2 1 0 2 2 1 0 Miro-like protein cobW PF02492.14 ETS74348.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 ETS74348.1 - 0.1 11.8 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ku_PK_bind PF08785.6 ETS74348.1 - 0.19 11.6 3.1 0.7 9.8 0.1 3.1 3 0 0 3 3 3 0 Ku C terminal domain like Arginase PF00491.16 ETS74349.1 - 2.3e-31 109.1 0.0 2.8e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ldh_2 PF02615.9 ETS74350.1 - 1.8e-102 342.5 0.0 2.1e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pkinase PF00069.20 ETS74351.1 - 1.8e-26 92.8 0.0 3.3e-26 92.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74351.1 - 4.9e-05 22.5 0.0 0.00067 18.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.23 ETS74353.1 - 2.6e-06 26.9 2.5 7.7e-06 25.4 1.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS74353.1 - 5.2e-05 23.1 1.3 0.00011 22.0 0.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box PF00646.28 ETS74354.1 - 0.00094 18.7 0.3 0.0029 17.2 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS74354.1 - 0.0064 16.1 0.1 0.021 14.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like TauD PF02668.11 ETS74355.1 - 1.7e-16 60.6 0.7 3e-16 59.8 0.4 1.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS74355.1 - 0.0048 15.8 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 CsiD MFS_1 PF07690.11 ETS74356.1 - 6.3e-45 153.4 48.7 1.7e-44 151.9 32.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS74356.1 - 1.8e-15 56.2 23.1 2.2e-15 55.8 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS74356.1 - 1.1e-12 47.2 14.0 1.1e-12 47.2 9.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS74356.1 - 0.011 15.5 1.7 0.16 11.7 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family DUF2530 PF10745.4 ETS74356.1 - 0.025 14.5 1.3 0.025 14.5 0.9 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) PUCC PF03209.10 ETS74356.1 - 4.4 5.9 25.6 0.34 9.5 8.2 3.3 2 1 2 4 4 4 0 PUCC protein UDPG_MGDP_dh_N PF03721.9 ETS74357.1 - 2.4e-47 160.7 0.6 1.9e-28 99.1 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETS74357.1 - 3.3e-32 110.5 0.0 8.9e-32 109.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 ETS74357.1 - 3.9e-23 81.6 0.0 1.2e-17 64.0 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 ETS74357.1 - 0.00049 19.1 0.0 0.00089 18.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 ETS74357.1 - 0.00075 19.3 0.1 1.5 8.6 0.1 3.0 2 1 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS74357.1 - 0.0063 16.2 0.7 4.4 7.0 0.1 2.9 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 ETS74357.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 ETS74357.1 - 0.016 14.8 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS74357.1 - 0.071 13.2 0.0 4.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 ETS74357.1 - 0.075 13.0 0.5 0.47 10.4 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain tRNA-synt_1 PF00133.17 ETS74358.1 - 9.9e-213 707.4 0.0 5.6e-212 704.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS74358.1 - 1.3e-30 106.1 0.8 3.9e-30 104.6 0.5 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS74358.1 - 1.7e-14 53.2 1.3 6.2e-06 25.1 0.2 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ETS74358.1 - 9.1e-13 47.9 1.6 4.9e-08 32.4 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 DUF4028 PF13220.1 ETS74358.1 - 0.029 14.0 0.3 0.095 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Peptidase_M28 PF04389.12 ETS74359.1 - 3.3e-18 66.0 0.3 7.9e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 ETS74359.1 - 9.4e-05 21.9 0.0 0.00028 20.4 0.0 1.8 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 ETS74359.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 ETS74359.1 - 0.0027 17.2 0.0 0.0059 16.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 ETS74359.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Glycos_transf_2 PF00535.21 ETS74361.1 - 6.6e-27 94.2 0.1 1.3e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETS74361.1 - 4.4e-10 39.7 0.1 2.4e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 ETS74361.1 - 4.9e-08 32.3 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 ETS74361.1 - 2.7e-06 27.6 0.0 6.5e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 MFS_1 PF07690.11 ETS74362.1 - 8.4e-22 77.3 32.3 3.3e-13 49.0 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 ETS74363.1 - 4.2e-46 156.6 0.2 3.8e-26 92.0 0.1 3.5 4 1 0 4 4 3 2 ABC transporter ABC_membrane PF00664.18 ETS74363.1 - 3.3e-33 115.2 43.0 3.5e-30 105.3 13.0 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS74363.1 - 3.8e-10 39.3 1.7 0.049 12.8 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS74363.1 - 2.1e-09 37.7 0.2 0.24 11.3 0.0 4.9 4 1 1 5 5 5 2 AAA domain DUF258 PF03193.11 ETS74363.1 - 7e-06 25.3 0.2 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS74363.1 - 1.4e-05 24.9 0.3 0.021 14.7 0.0 3.2 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS74363.1 - 2.7e-05 24.2 1.3 0.047 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 ETS74363.1 - 9.2e-05 22.9 0.1 0.63 10.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 ETS74363.1 - 0.0001 21.7 0.3 0.43 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS74363.1 - 0.00048 20.2 0.6 1.5 8.9 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS74363.1 - 0.0011 18.3 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 ETS74363.1 - 0.0012 18.4 0.5 0.1 12.0 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 ETS74363.1 - 0.0013 18.5 1.5 0.077 12.8 0.0 2.8 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.7 ETS74363.1 - 0.0017 17.4 0.9 1.1 8.3 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.1 ETS74363.1 - 0.016 15.1 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 ETS74363.1 - 0.016 14.9 0.1 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 ETS74363.1 - 0.019 13.8 0.7 0.76 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETS74363.1 - 0.029 14.6 0.0 8.4 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 ETS74363.1 - 0.044 13.3 0.1 4 6.8 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 ETS74363.1 - 0.052 12.9 1.1 4.6 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 ETS74363.1 - 0.056 12.8 1.1 5.9 6.2 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 ETS74363.1 - 0.061 12.2 0.2 5.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 ETS74363.1 - 0.07 12.9 1.3 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 ETS74363.1 - 0.071 12.8 0.6 8 6.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS74363.1 - 0.084 13.0 0.1 1.5 9.0 0.0 3.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) SH3BGR PF04908.10 ETS74363.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein AAA_30 PF13604.1 ETS74363.1 - 0.1 12.1 0.2 10 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DEAD PF00270.24 ETS74363.1 - 0.15 11.5 0.2 16 4.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 ETS74363.1 - 0.18 12.6 0.0 17 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 ETS74364.1 - 1.6e-08 33.7 22.5 1e-07 30.9 12.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS74364.1 - 3.9e-06 25.5 2.9 3.9e-06 25.5 2.0 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein DUF3328 PF11807.3 ETS74365.1 - 1.2e-15 57.8 0.2 2.1e-15 57.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Pyridox_oxidase PF01243.15 ETS74366.1 - 0.00012 21.9 1.3 11 6.1 0.0 4.6 2 2 3 5 5 5 1 Pyridoxamine 5'-phosphate oxidase ProQ PF04352.8 ETS74366.1 - 0.00052 19.6 6.2 2 8.0 0.1 4.6 3 1 2 5 5 5 2 ProQ/FINO family IceA2 PF05862.6 ETS74366.1 - 0.00096 18.8 3.6 60 3.4 0.1 5.0 5 0 0 5 5 5 0 Helicobacter pylori IceA2 protein DUF2358 PF10184.4 ETS74366.1 - 0.0084 16.0 0.0 1.2e+02 2.6 0.0 4.6 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2358) Amidohydro_5 PF13594.1 ETS74366.1 - 0.011 15.5 2.5 9.6 6.1 0.1 3.4 3 0 0 3 3 3 0 Amidohydrolase DUF3659 PF12396.3 ETS74366.1 - 0.021 14.5 0.4 6 6.6 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3659) NADPH_Ox PF08414.5 ETS74366.1 - 0.051 13.6 0.0 8.1 6.6 0.0 2.5 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase MrpF_PhaF PF04066.8 ETS74366.1 - 0.1 12.8 6.6 9.7 6.5 0.1 4.6 5 0 0 5 5 5 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Bombolitin PF08096.6 ETS74366.1 - 0.11 12.6 2.1 5.5 7.2 0.0 3.8 4 0 0 4 4 4 0 Bombolitin family UDPG_MGDP_dh PF00984.14 ETS74366.1 - 0.74 10.0 4.6 4.8 7.4 0.1 3.3 2 2 2 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain HTH_AsnC-type PF13404.1 ETS74366.1 - 8.6 5.9 12.4 8.4 6.0 0.1 5.2 5 1 0 5 5 5 0 AsnC-type helix-turn-helix domain Collagen PF01391.13 ETS74367.1 - 4.5e-05 22.9 1.8 7.1e-05 22.2 1.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GFO_IDH_MocA PF01408.17 ETS74367.1 - 0.00063 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA PF00004.24 ETS74368.1 - 2.3e-41 141.0 0.0 1.2e-14 54.6 0.0 6.3 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 ETS74368.1 - 3e-41 141.0 0.6 2.7e-40 137.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 ETS74368.1 - 4.4e-30 104.9 22.8 3.4e-26 92.2 0.0 6.6 5 2 1 6 6 6 2 AAA domain AAA_19 PF13245.1 ETS74368.1 - 1.8e-18 66.0 0.7 0.00011 21.8 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_30 PF13604.1 ETS74368.1 - 1.7e-13 50.6 10.6 0.0013 18.3 0.0 6.6 6 0 0 6 6 5 4 AAA domain AAA_17 PF13207.1 ETS74368.1 - 1.9e-13 51.2 2.2 0.084 13.6 0.0 5.4 4 0 0 4 4 4 4 AAA domain AAA_22 PF13401.1 ETS74368.1 - 6.3e-10 39.3 16.4 0.0087 16.2 0.1 8.5 8 3 0 8 8 7 3 AAA domain AAA_5 PF07728.9 ETS74368.1 - 6.5e-10 38.8 5.6 0.11 12.2 0.0 5.9 7 0 0 7 7 7 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS74368.1 - 4.7e-09 35.7 0.1 0.036 13.2 0.0 5.0 4 1 1 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS74368.1 - 1.7e-08 34.8 3.0 1.5 9.1 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 ETS74368.1 - 1.3e-07 31.7 6.0 0.31 11.0 0.0 6.0 5 0 0 5 5 4 3 AAA ATPase domain IstB_IS21 PF01695.12 ETS74368.1 - 1.8e-07 30.7 0.0 3.9 6.8 0.0 5.0 4 0 0 4 4 4 3 IstB-like ATP binding protein Torsin PF06309.6 ETS74368.1 - 8e-07 28.9 0.0 5.5 6.8 0.0 4.6 4 0 0 4 4 4 2 Torsin RNA_helicase PF00910.17 ETS74368.1 - 2.6e-06 27.5 4.1 1.6 8.9 0.0 5.4 5 0 0 5 5 5 2 RNA helicase AAA_33 PF13671.1 ETS74368.1 - 0.0003 20.6 11.4 1.5 8.7 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 ETS74368.1 - 0.016 14.5 9.9 5.5 6.3 0.0 5.8 5 1 1 6 6 6 0 AAA domain AAA_28 PF13521.1 ETS74368.1 - 0.032 14.1 11.9 2 8.3 0.0 5.3 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.1 ETS74368.1 - 0.1 12.1 18.4 0.3 10.6 0.4 5.2 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.17 ETS74368.1 - 0.12 11.7 6.1 0.38 10.1 0.0 4.3 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain BRE PF06113.7 ETS74368.1 - 0.17 10.9 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) SH3_2 PF07653.12 ETS74369.1 - 0.039 13.4 0.7 1.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Variant SH3 domain MFS_1 PF07690.11 ETS74370.1 - 4.7e-34 117.6 53.7 4e-21 75.1 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74370.1 - 4e-05 22.3 37.8 0.00037 19.1 10.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS74370.1 - 1.4 8.7 10.4 3.4 7.5 3.3 3.4 3 0 0 3 3 3 0 MFS_1 like family Fungal_trans PF04082.13 ETS74371.1 - 3.2e-16 58.9 0.2 7.8e-16 57.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74372.1 - 5.2e-09 35.8 11.6 8.4e-09 35.2 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lamp PF01299.12 ETS74374.1 - 0.34 9.9 2.0 0.47 9.5 0.2 1.8 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) CENP-H PF05837.7 ETS74374.1 - 0.43 10.7 2.4 0.73 10.0 1.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) MFS_1 PF07690.11 ETS74375.1 - 2.1e-30 105.6 49.4 3.2e-27 95.1 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS74375.1 - 0.018 15.0 0.2 0.018 15.0 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) V_ATPase_I PF01496.14 ETS74375.1 - 4.1 5.1 6.6 6.9 4.3 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 ETS74376.1 - 3.8e-32 111.3 27.1 3.8e-32 111.3 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74376.1 - 1.2e-11 43.9 8.4 1.2e-11 43.9 5.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS74376.1 - 1e-07 30.5 1.9 1.6e-07 29.9 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bestrophin PF01062.16 ETS74378.1 - 1.3e-47 162.1 0.6 5.5e-46 156.8 0.4 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TraQ PF09679.5 ETS74379.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) p450 PF00067.17 ETS74380.1 - 1.1e-13 50.5 0.2 2.9e-13 49.1 0.2 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF489 PF04356.7 ETS74380.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Trp_DMAT PF11991.3 ETS74381.1 - 2e-87 293.7 0.0 2.3e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Arylsulfotran_2 PF14269.1 ETS74382.1 - 1.1e-60 205.2 2.5 1.6e-60 204.7 1.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS74382.1 - 3.1e-14 52.3 1.1 6.5e-13 48.0 0.8 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.16 ETS74382.1 - 0.003 17.0 0.2 19 5.0 0.0 4.4 4 0 0 4 4 4 2 PQQ enzyme repeat Glyco_hydro_3 PF00933.16 ETS74383.1 - 4.4e-91 304.9 0.0 6.2e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS74383.1 - 1.4e-54 185.0 1.1 1.1e-53 182.1 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS74383.1 - 5.1e-22 77.5 1.8 7.7e-22 77.0 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 ETS74384.1 - 6.5e-20 71.0 0.2 1.1e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain TRI12 PF06609.8 ETS74385.1 - 7.6e-24 83.8 23.3 1e-23 83.4 16.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS74385.1 - 4.4e-22 78.2 51.2 4.5e-22 78.2 33.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S15 PF02129.13 ETS74386.1 - 1.3e-39 136.2 0.2 1.1e-37 129.9 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS74386.1 - 2.5e-23 83.1 0.0 4.5e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS74386.1 - 8.5e-07 29.0 0.3 2.6e-06 27.5 0.1 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS74386.1 - 0.0045 15.5 0.0 0.92 7.9 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 ETS74386.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase ABC_tran PF00005.22 ETS74387.1 - 1.1e-40 139.1 0.0 3e-22 79.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS74387.1 - 9.4e-28 97.3 30.1 7.7e-20 71.4 1.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS74387.1 - 6.6e-14 51.6 4.5 5.9e-05 22.3 0.4 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS74387.1 - 6.8e-12 45.9 0.0 0.22 11.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain AAA_33 PF13671.1 ETS74387.1 - 6.6e-08 32.5 0.0 0.011 15.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 ETS74387.1 - 4.5e-06 26.8 0.7 0.11 12.6 0.3 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 ETS74387.1 - 9.2e-06 26.1 0.0 0.022 15.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 ETS74387.1 - 1.2e-05 24.7 0.6 0.18 11.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS74387.1 - 2.4e-05 24.3 1.0 0.059 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 ETS74387.1 - 5.3e-05 22.9 0.8 0.18 11.4 0.1 2.8 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETS74387.1 - 0.00031 21.5 1.1 0.13 13.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ETS74387.1 - 0.00043 20.6 0.1 0.69 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 ETS74387.1 - 0.00073 19.0 0.4 0.19 11.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 ETS74387.1 - 0.00093 18.9 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 ETS74387.1 - 0.001 19.0 0.2 0.17 11.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 ETS74387.1 - 0.0019 17.1 1.6 0.15 10.9 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 ETS74387.1 - 0.002 18.3 0.1 2.1 8.5 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS74387.1 - 0.0021 17.9 0.0 0.18 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS74387.1 - 0.0027 18.0 0.2 1 9.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS74387.1 - 0.003 17.0 0.3 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 ETS74387.1 - 0.0039 16.9 0.6 0.61 9.8 0.0 3.5 4 0 0 4 4 2 1 Part of AAA domain AAA_25 PF13481.1 ETS74387.1 - 0.0046 16.3 0.0 1.1 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 ETS74387.1 - 0.012 15.4 0.1 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 ETS74387.1 - 0.014 14.4 0.0 2.2 7.3 0.0 2.5 2 1 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 ETS74387.1 - 0.018 14.2 0.2 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 ETS74387.1 - 0.025 14.1 0.1 6.8 6.1 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 ETS74387.1 - 0.054 13.1 0.1 7.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 ETS74387.1 - 0.059 13.1 1.0 4.7 7.0 0.2 2.4 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 ETS74387.1 - 0.074 11.6 0.3 0.62 8.5 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 ETS74387.1 - 0.076 12.9 3.4 0.67 9.9 0.1 3.7 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit GTP_EFTU PF00009.22 ETS74387.1 - 0.096 12.1 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Trehalose_PPase PF02358.11 ETS74387.1 - 0.13 11.1 0.1 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase AAA_10 PF12846.2 ETS74387.1 - 0.16 11.4 2.0 13 5.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_24 PF13479.1 ETS74387.1 - 0.24 10.9 0.0 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RTA1 PF04479.8 ETS74388.1 - 4.3e-48 163.7 3.9 4.3e-48 163.7 2.7 1.4 2 0 0 2 2 2 1 RTA1 like protein p450 PF00067.17 ETS74389.1 - 1.2e-74 251.5 0.0 1.4e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.12 ETS74390.1 - 2.1e-40 138.3 0.7 2.7e-40 138.0 0.5 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.3 ETS74392.1 - 5.8e-07 28.4 0.0 1.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GSDH PF07995.6 ETS74394.1 - 4.6e-08 32.5 0.0 8.2e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.1 ETS74394.1 - 0.1 12.2 3.1 8.6 6.1 0.0 3.8 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat PTR2 PF00854.16 ETS74395.1 - 2.7e-30 105.3 15.9 1.8e-28 99.3 6.9 3.2 1 1 1 2 2 2 1 POT family DUF1469 PF07332.6 ETS74395.1 - 0.0048 16.6 0.1 0.0048 16.6 0.1 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1469) DUF4311 PF14188.1 ETS74395.1 - 0.033 13.6 9.3 0.17 11.3 2.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4311) CcmH PF03918.9 ETS74395.1 - 0.17 10.9 1.3 6.1 5.8 0.0 2.7 2 1 0 2 2 2 0 Cytochrome C biogenesis protein Herpes_US9 PF06072.6 ETS74395.1 - 0.25 11.2 3.1 7.8 6.4 0.2 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Amidohydro_4 PF13147.1 ETS74396.1 - 9e-20 71.8 0.0 1.2e-19 71.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS74396.1 - 4.6e-13 48.7 0.0 9.8e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS74396.1 - 1.4e-12 47.9 0.0 5e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 ETS74396.1 - 0.0043 16.3 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 ETS74396.1 - 0.009 16.1 0.1 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Asp PF00026.18 ETS74397.1 - 2.9e-42 145.0 0.1 3.6e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 ETS74397.1 - 0.00025 20.6 0.1 0.0026 17.2 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 ETS74397.1 - 0.0052 17.2 0.6 12 6.5 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease RuvA_C PF07499.8 ETS74397.1 - 0.2 11.8 0.9 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 RuvA, C-terminal domain Rad1 PF02144.11 ETS74398.1 - 0.098 11.4 0.1 0.21 10.3 0.0 1.4 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 FF PF01846.14 ETS74399.1 - 6.2e-13 48.4 11.6 2.9e-12 46.3 0.6 3.6 3 0 0 3 3 3 2 FF domain WW PF00397.21 ETS74399.1 - 3.6e-08 33.1 3.7 3.6e-08 33.1 2.6 2.6 2 0 0 2 2 2 1 WW domain DLH PF01738.13 ETS74400.1 - 3.3e-26 91.9 0.0 4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS74400.1 - 0.00018 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF953 PF06110.6 ETS74403.1 - 2.3e-20 72.1 0.1 2.8e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 ETS74403.1 - 0.00025 20.6 0.1 0.00042 19.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin PAP2 PF01569.16 ETS74404.1 - 2.4e-22 79.0 0.3 2.4e-22 79.0 0.2 2.2 1 1 1 2 2 2 1 PAP2 superfamily YibE_F PF07907.6 ETS74404.1 - 0.00076 18.7 1.5 0.006 15.8 1.0 2.0 2 0 0 2 2 2 1 YibE/F-like protein SNARE_assoc PF09335.6 ETS74404.1 - 0.028 14.6 3.1 0.41 10.8 1.4 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein RseC_MucC PF04246.7 ETS74404.1 - 0.064 12.8 1.4 6 6.4 0.2 2.9 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Dynamin_N PF00350.18 ETS74405.1 - 5.4e-21 75.1 0.0 5.1e-20 71.9 0.0 2.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS74405.1 - 9.4e-11 41.0 0.0 3.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 ETS74405.1 - 0.002 18.0 0.2 0.002 18.0 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.22 ETS74405.1 - 0.015 15.5 0.0 0.094 13.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.8 ETS74405.1 - 0.073 11.8 0.0 0.24 10.1 0.0 1.8 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 ETS74405.1 - 0.15 12.6 0.0 0.95 9.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Sugar_tr PF00083.19 ETS74406.1 - 2.6e-82 276.7 21.3 3e-82 276.5 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74406.1 - 8.4e-29 100.3 19.5 1.2e-28 99.9 13.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS74406.1 - 9.8e-05 20.7 5.4 0.00026 19.3 1.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 ETS74406.1 - 0.0056 16.1 4.4 0.0056 16.1 3.1 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 YrhK PF14145.1 ETS74406.1 - 0.32 10.6 7.4 15 5.3 2.9 3.6 2 1 0 2 2 2 0 YrhK-like protein A2M_N PF01835.14 ETS74407.1 - 0.0091 16.2 0.0 0.15 12.2 0.0 2.6 2 1 0 2 2 2 1 MG2 domain DUF1212 PF06738.7 ETS74407.1 - 1.3 8.4 8.3 3.9 6.8 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) p450 PF00067.17 ETS74408.1 - 6.3e-29 100.8 0.0 8.4e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glycoamylase PF10091.4 ETS74408.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase Peroxidase_2 PF01328.12 ETS74409.1 - 7.8e-44 149.6 0.3 9.3e-44 149.3 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Phosphoesterase PF04185.9 ETS74411.1 - 1.5e-32 113.2 2.1 2e-31 109.5 1.0 2.2 1 1 1 2 2 2 1 Phosphoesterase family Sulfatase PF00884.18 ETS74411.1 - 0.02 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Sulfatase adh_short_C2 PF13561.1 ETS74412.1 - 1.7e-31 109.8 0.0 2.1e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS74412.1 - 4.4e-27 95.0 0.1 5.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74412.1 - 1.6e-08 34.4 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS74412.1 - 0.024 14.0 0.0 0.67 9.3 0.0 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 ETS74412.1 - 0.041 12.9 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 ETS74412.1 - 0.11 12.2 0.2 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 ETS74413.1 - 8e-17 61.6 0.2 1.3e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74413.1 - 6.3e-09 35.7 0.1 9.1e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Peptidase_M19 PF01244.16 ETS74414.1 - 5.6e-70 235.8 0.0 6.8e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.11 ETS74415.1 - 4.2e-31 107.9 25.5 4.2e-31 107.9 17.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Adeno_E3_14_5 PF04834.7 ETS74415.1 - 2.6 8.5 5.9 2.1 8.8 0.2 3.0 2 1 0 3 3 3 0 Early E3 14.5 kDa protein VCBS PF13517.1 ETS74416.1 - 1.5e-16 60.4 10.0 5.9e-06 26.5 1.4 3.8 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS74416.1 - 9.9e-16 56.9 17.6 0.0017 17.9 0.6 4.9 4 0 0 4 4 4 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 ETS74416.1 - 1.1e-08 34.7 3.8 0.16 11.4 0.3 4.2 3 1 1 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 ETS74416.1 - 0.016 14.5 13.7 3.2 7.2 0.4 4.3 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.27 ETS74416.1 - 0.21 10.9 9.4 3.6 7.1 0.1 4.2 4 0 0 4 4 4 0 EF hand Rcd1 PF04078.8 ETS74417.1 - 1.1e-129 430.9 3.4 1.3e-129 430.6 2.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.9 ETS74417.1 - 0.16 11.0 3.8 9.2 5.2 2.6 3.0 1 1 0 1 1 1 0 V-ATPase subunit H BAF1_ABF1 PF04684.8 ETS74417.1 - 2.2 7.0 9.0 3.7 6.2 6.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UvrD_C PF13361.1 ETS74419.1 - 2.5e-78 264.0 0.0 3.3e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 ETS74419.1 - 7.7e-63 212.6 0.6 4.7e-61 206.8 0.4 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 ETS74419.1 - 5.4e-14 52.1 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 ETS74419.1 - 1e-12 47.5 0.4 1.1e-11 44.2 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS74419.1 - 6.4e-06 25.8 0.2 0.00028 20.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETS74419.1 - 1.1e-05 25.0 0.1 0.2 11.1 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 ETS74419.1 - 0.0026 17.1 0.0 0.025 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 ETS74419.1 - 0.022 14.3 0.3 0.097 12.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain Amidohydro_4 PF13147.1 ETS74420.1 - 3e-12 47.1 1.5 3.3e-11 43.7 1.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS74420.1 - 1e-06 28.6 0.0 0.0001 22.1 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 ETS74420.1 - 9.8e-06 25.0 0.0 6.1e-05 22.4 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS74420.1 - 0.00026 20.7 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_3 PF00933.16 ETS74421.1 - 4.1e-53 180.3 0.0 5.7e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 ETS74421.1 - 0.006 16.5 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 ETS74421.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.1 ETS74421.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS74421.1 - 0.14 12.3 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 ETS74422.1 - 9e-35 120.3 0.3 1e-33 116.8 0.0 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.11 ETS74423.1 - 5.3e-33 114.2 0.0 6.1e-26 91.0 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 ETS74423.1 - 1.6e-31 109.2 0.0 2.3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.15 ETS74424.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_31 PF01055.21 ETS74425.1 - 2e-110 369.6 0.2 2.5e-110 369.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS74425.1 - 2.4e-16 59.3 0.0 1.8e-15 56.5 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.16 ETS74426.1 - 2.8e-65 220.2 0.0 3.6e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS74426.1 - 4.4e-57 193.2 0.1 6.9e-57 192.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS74426.1 - 4.2e-23 81.0 2.2 7.7e-23 80.2 0.2 2.5 3 0 0 3 3 3 1 Fibronectin type III-like domain Sugar-bind PF04198.8 ETS74426.1 - 0.0038 16.1 0.1 0.0078 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain HET PF06985.6 ETS74427.1 - 2.9e-29 102.0 0.0 5.9e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_1_2 PF00155.16 ETS74428.1 - 1.3e-10 40.8 0.0 1.1e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS74428.1 - 0.0061 15.1 0.0 0.034 12.7 0.0 2.0 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase VHS PF00790.14 ETS74429.1 - 4.6e-35 120.3 0.0 1e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 ETS74429.1 - 1.2e-15 56.8 0.2 2.3e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS74429.1 - 4e-15 54.9 0.2 9.3e-15 53.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 ETS74429.1 - 4.2e-13 48.5 0.0 1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 ETS74429.1 - 0.032 14.2 2.2 0.082 12.8 0.9 2.1 2 0 0 2 2 2 0 GAT domain UIM PF02809.15 ETS74429.1 - 0.063 12.8 6.9 0.17 11.5 4.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 ETS74429.1 - 0.14 11.5 0.4 0.28 10.6 0.3 1.4 1 0 0 1 1 1 0 TIR domain ATG13 PF10033.4 ETS74430.1 - 7.5e-63 212.0 0.0 1.3e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF1237 PF06824.6 ETS74431.1 - 1.6e-161 537.6 0.1 1.9e-161 537.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Glyco_hydro_92 PF07971.7 ETS74432.1 - 8.5e-169 562.3 0.0 1e-168 562.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Cyt-b5 PF00173.23 ETS74433.1 - 2.2e-13 49.8 0.0 5.2e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 ETS74433.1 - 7.6e-12 44.3 0.0 3.3e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 ETS74433.1 - 2.5e-10 40.8 0.0 6.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 ETS74433.1 - 1e-09 38.1 0.0 2.9e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 ETS74434.1 - 4.4e-10 39.3 11.9 6.8e-10 38.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS74434.1 - 0.0005 19.0 0.0 0.0016 17.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zds_C PF08632.5 ETS74436.1 - 6e-31 105.6 0.4 1.1e-30 104.7 0.3 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bac_rhamnosid PF05592.6 ETS74437.1 - 1e-20 73.4 3.2 1.1e-18 66.7 2.1 2.5 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase SET PF00856.23 ETS74438.1 - 2.1e-05 24.8 0.0 0.24 11.7 0.0 3.1 2 1 0 2 2 2 2 SET domain Cu-oxidase_3 PF07732.10 ETS74440.1 - 1.4e-40 137.7 6.6 4.1e-40 136.1 1.8 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS74440.1 - 1.5e-36 124.9 0.8 1.5e-36 124.9 0.6 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS74440.1 - 1.2e-34 119.4 1.2 5.8e-34 117.2 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Glyco_hydro_43 PF04616.9 ETS74441.1 - 4e-54 183.6 5.6 5.8e-54 183.1 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SNF2_N PF00176.18 ETS74442.1 - 2.1e-74 249.9 0.7 6.5e-74 248.4 0.5 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS74442.1 - 3.5e-11 42.8 0.0 1.3e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 ETS74442.1 - 0.002 17.5 0.2 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 Nucleoplasmin PF03066.10 ETS74442.1 - 0.0069 15.9 0.1 0.0069 15.9 0.1 4.4 3 1 0 3 3 3 1 Nucleoplasmin YpzG PF14139.1 ETS74442.1 - 0.046 13.6 0.4 2.6 8.0 0.1 2.8 2 0 0 2 2 2 0 YpzG-like protein zf-AD PF07776.10 ETS74442.1 - 0.078 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DZR PF12773.2 ETS74442.1 - 0.087 12.6 0.3 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ran-binding PF05508.6 ETS74443.1 - 5.4e-77 258.6 0.0 7.2e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 ETS74444.1 - 1.1e-43 148.8 0.0 1.9e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS74444.1 - 2.8e-21 75.5 0.0 8.1e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS74444.1 - 6.7e-08 32.5 2.1 1.8e-07 31.1 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS74444.1 - 0.00017 21.5 0.0 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 ETS74444.1 - 0.012 14.2 0.2 0.023 13.3 0.2 1.4 1 0 0 1 1 1 0 G-protein alpha subunit PhageP22-tail PF09251.5 ETS74444.1 - 2.5 6.2 8.2 3.7 5.7 5.7 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike PEPCK_ATP PF01293.15 ETS74445.1 - 1.4e-215 716.2 0.0 1.6e-215 716.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 ETS74445.1 - 0.075 12.5 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETS74445.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS74445.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain 2-Hacid_dh_C PF02826.14 ETS74446.1 - 2.4e-38 131.0 0.0 3.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS74446.1 - 3.2e-17 62.2 0.1 4e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 ETS74446.1 - 2.3e-05 24.7 0.1 5.6e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETS74446.1 - 0.00032 20.5 0.2 0.00055 19.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 ETS74446.1 - 0.001 18.9 0.8 0.003 17.4 0.5 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 ETS74446.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ANF_receptor PF01094.23 ETS74446.1 - 0.012 14.4 0.0 0.036 12.8 0.0 1.8 1 1 1 2 2 2 0 Receptor family ligand binding region UCH_1 PF13423.1 ETS74447.1 - 1.3e-48 165.9 0.1 2.1e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 ETS74447.1 - 2.3e-25 89.7 0.0 5.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 ETS74447.1 - 2.3e-12 46.6 0.0 2.1e-11 43.4 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tnp_zf-ribbon_2 PF13842.1 ETS74447.1 - 0.047 14.1 0.5 14 6.1 0.0 2.8 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Macoilin PF09726.4 ETS74448.1 - 0.21 9.8 6.7 0.25 9.5 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_23 PF13489.1 ETS74449.1 - 4e-14 52.6 0.0 8.7e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74449.1 - 6.5e-06 26.5 0.0 0.0011 19.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS74449.1 - 6.6e-06 25.3 0.0 0.0037 16.4 0.0 2.3 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS74449.1 - 5.5e-05 23.5 0.0 0.00029 21.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS74449.1 - 0.00089 19.5 0.0 0.0074 16.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74449.1 - 0.002 17.6 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74449.1 - 0.012 16.2 0.0 0.09 13.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain NmrA PF05368.8 ETS74450.1 - 3e-13 49.5 0.0 4.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74450.1 - 5.4e-12 46.0 0.0 1.2e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS74450.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2811 PF10929.3 ETS74450.1 - 0.092 12.7 0.6 0.55 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2811) AATase PF07247.7 ETS74451.1 - 1.7e-23 82.9 0.0 4.1e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 ETS74451.1 - 2.4e-10 39.7 1.1 3.9e-10 39.0 0.8 1.3 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 ETS74451.1 - 0.00043 19.9 0.2 0.00077 19.0 0.1 1.4 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain T2SE_Nter PF05157.10 ETS74451.1 - 0.043 13.8 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain FMO-like PF00743.14 ETS74452.1 - 7.4e-67 225.7 0.0 1.2e-66 224.9 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS74452.1 - 1.9e-22 80.3 0.0 2.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS74452.1 - 1.7e-09 37.1 0.2 1.6e-07 30.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS74452.1 - 1.2e-08 35.0 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS74452.1 - 2.5e-08 33.8 0.0 8.9e-08 32.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS74452.1 - 9.4e-07 28.7 0.0 1.9e-05 24.4 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS74452.1 - 6.6e-05 23.2 0.0 0.0018 18.6 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS74452.1 - 0.00013 21.1 0.0 0.00042 19.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 ETS74452.1 - 0.00039 19.4 0.0 0.019 13.8 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS74452.1 - 0.00045 19.3 0.2 0.002 17.2 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_10 PF13460.1 ETS74452.1 - 0.0028 17.6 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 ETS74452.1 - 0.003 17.6 0.0 0.65 10.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS74452.1 - 0.0042 17.3 0.0 2.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS74452.1 - 0.006 15.7 0.0 0.6 9.2 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS74452.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 ETS74452.1 - 0.017 13.5 0.1 0.048 12.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.7 ETS74452.1 - 0.067 12.5 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 ETS74452.1 - 0.13 12.2 0.1 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pedibin PF08182.6 ETS74452.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family GFA PF04828.9 ETS74453.1 - 1.4e-16 60.1 2.5 2.2e-08 33.9 0.0 2.9 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 ETS74453.1 - 6.1 6.7 13.4 5 7.0 0.6 3.7 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like Yip1 PF04893.12 ETS74454.1 - 2.2 7.7 14.8 0.18 11.3 4.8 2.2 1 1 1 2 2 2 0 Yip1 domain 4HBT PF03061.17 ETS74456.1 - 4.4e-13 49.1 0.1 6.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 ETS74456.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF3611 PF12263.3 ETS74458.1 - 0.016 14.5 3.2 0.039 13.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) 60KD_IMP PF02096.15 ETS74458.1 - 0.035 13.7 1.9 0.047 13.3 0.1 1.9 1 1 1 2 2 2 0 60Kd inner membrane protein DUF805 PF05656.9 ETS74458.1 - 0.55 10.0 10.3 1.5 8.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) MASE1 PF05231.9 ETS74458.1 - 1.1 8.2 10.0 8.5 5.2 7.2 1.8 1 1 0 1 1 1 0 MASE1 Peroxidase_2 PF01328.12 ETS74459.1 - 1.6e-30 105.8 1.0 2e-30 105.5 0.7 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.16 ETS74460.1 - 3.3e-89 298.8 0.0 4.6e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS74460.1 - 2.4e-48 164.6 0.0 8.5e-47 159.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS74460.1 - 7.9e-18 64.1 0.0 1.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Myb_DNA-bind_4 PF13837.1 ETS74461.1 - 5.5e-05 23.2 0.1 0.00011 22.2 0.1 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS74461.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS74461.1 - 0.0022 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 ETS74461.1 - 0.075 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3280 PF11684.3 ETS74461.1 - 0.081 13.1 0.0 0.081 13.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2380) Med3 PF11593.3 ETS74461.1 - 0.82 8.8 8.4 1 8.5 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC2_membrane PF01061.19 ETS74462.1 - 3.2e-79 264.9 59.7 4.1e-44 150.2 14.1 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS74462.1 - 2e-37 128.5 0.3 1.9e-18 67.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 ETS74462.1 - 2.9e-29 100.7 6.8 4.3e-26 90.5 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 ETS74462.1 - 7.4e-08 31.8 27.7 5.3e-05 22.4 5.6 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 ETS74462.1 - 2.5e-06 27.3 1.9 0.032 14.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 ETS74462.1 - 2.8e-06 26.8 0.1 0.012 14.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC_trans_N PF14510.1 ETS74462.1 - 4.6e-06 26.6 0.5 2.1e-05 24.5 0.0 2.4 3 0 0 3 3 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 ETS74462.1 - 1.6e-05 24.3 0.4 0.0059 16.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 ETS74462.1 - 3e-05 24.8 0.0 0.035 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETS74462.1 - 4.3e-05 23.6 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS74462.1 - 5.1e-05 23.4 0.1 0.41 10.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS74462.1 - 0.00014 21.1 0.0 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS74462.1 - 0.00016 21.1 0.4 0.0096 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS74462.1 - 0.00029 20.8 0.0 0.16 11.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 ETS74462.1 - 0.00085 18.9 0.7 0.84 9.2 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 ETS74462.1 - 0.0022 18.3 0.0 0.79 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETS74462.1 - 0.0034 16.6 0.1 0.33 10.1 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 ETS74462.1 - 0.0065 16.1 1.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 ETS74462.1 - 0.019 15.1 1.1 8.5 6.6 0.0 4.1 4 0 0 4 4 4 0 RNA helicase Miro PF08477.8 ETS74462.1 - 0.022 15.2 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 ETS74462.1 - 0.022 14.2 0.2 0.79 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 ETS74462.1 - 0.027 14.6 0.1 16 5.7 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS74462.1 - 0.04 13.6 0.6 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 ETS74462.1 - 0.042 13.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 ETS74462.1 - 0.045 13.2 1.7 1.4 8.4 0.1 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 ETS74462.1 - 0.22 10.6 0.9 7.6 5.5 0.1 2.7 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 ETS74462.1 - 0.36 10.3 2.0 9.6 5.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS74462.1 - 0.41 10.5 5.2 0.48 10.3 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_15 PF13175.1 ETS74462.1 - 0.51 9.3 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.2 ETS74464.1 - 1.2e-88 291.5 25.1 1.7e-16 60.3 0.3 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74464.1 - 1.5e-49 163.4 22.6 4e-07 29.5 0.0 12.4 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 ETS74464.1 - 1.2e-44 149.8 8.7 2.4e-09 37.4 0.0 7.8 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74464.1 - 1.5e-32 108.3 13.1 0.0014 18.6 0.0 12.2 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 ETS74464.1 - 4.8e-24 83.8 19.5 3.5e-06 27.0 0.0 8.8 3 2 8 11 11 10 8 Ankyrin repeats (many copies) NACHT PF05729.7 ETS74464.1 - 1.9e-08 34.1 0.1 4.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 ETS74464.1 - 4.7e-06 25.8 1.5 0.036 13.0 0.4 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.1 ETS74464.1 - 5.3e-05 23.2 0.0 0.00018 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 ETS74464.1 - 0.00018 21.1 0.0 0.00051 19.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS74464.1 - 0.0022 18.1 0.0 0.0074 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS74464.1 - 0.0042 17.2 0.0 0.017 15.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) rRNA_proc-arch PF13234.1 ETS74464.1 - 0.0075 15.4 0.0 0.074 12.2 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain Arch_ATPase PF01637.13 ETS74464.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_30 PF13604.1 ETS74464.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETS74464.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 ETS74464.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETS74464.1 - 0.026 14.2 0.1 0.08 12.6 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 ETS74464.1 - 0.038 12.6 0.0 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 ETS74464.1 - 0.052 13.8 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS74464.1 - 0.053 12.3 0.0 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 ETS74464.1 - 0.054 13.2 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.22 ETS74464.1 - 0.056 13.7 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_35 PF14516.1 ETS74464.1 - 0.056 12.0 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_10 PF12846.2 ETS74464.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 ETS74464.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DAP3 PF10236.4 ETS74464.1 - 0.19 10.6 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF1843 PF08898.5 ETS74464.1 - 0.53 10.3 0.0 0.53 10.3 0.0 5.3 6 0 0 6 6 5 0 Domain of unknown function (DUF1843) Meth_synt_2 PF01717.13 ETS74466.1 - 3.1e-17 62.5 0.0 2.1e-12 46.6 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS74466.1 - 3.1e-05 23.4 0.0 0.053 12.7 0.0 3.2 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain IncA PF04156.9 ETS74467.1 - 0.00015 21.3 0.4 0.00029 20.5 0.3 1.4 1 0 0 1 1 1 1 IncA protein EcoR124_C PF12008.3 ETS74467.1 - 0.043 12.9 0.1 0.081 12.0 0.1 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Catalase PF00199.14 ETS74468.1 - 4.5e-163 542.4 0.0 5.2e-163 542.1 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 ETS74468.1 - 0.00048 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Nup160 PF11715.3 ETS74468.1 - 0.23 9.5 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Oxidored_molyb PF00174.14 ETS74469.1 - 8.8e-48 161.9 0.0 2.4e-46 157.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 ETS74469.1 - 2.3e-24 85.4 3.7 3.9e-24 84.7 2.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Response_reg PF00072.19 ETS74470.1 - 3e-16 59.4 0.1 8.4e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 ETS74470.1 - 6.5e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS74470.1 - 5.2e-09 35.9 0.1 4.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain FleQ PF06490.6 ETS74470.1 - 0.032 14.3 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ GAF_3 PF13492.1 ETS74470.1 - 0.083 12.9 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 GAF domain Abhydrolase_6 PF12697.2 ETS74471.1 - 2.1e-27 96.5 0.5 2.3e-27 96.3 0.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74471.1 - 9.2e-16 57.9 0.0 1.5e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS74471.1 - 0.00011 22.5 0.0 0.00043 20.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 ETS74471.1 - 0.00024 20.7 0.0 0.00067 19.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 ETS74471.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 ETS74471.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.8 ETS74471.1 - 0.053 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold GtrA PF04138.9 ETS74472.1 - 0.017 15.0 3.1 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 GtrA-like protein DUF1705 PF08019.7 ETS74472.1 - 0.22 11.0 9.2 0.27 10.7 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) p450 PF00067.17 ETS74473.1 - 2.3e-40 138.5 0.0 3.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS74474.1 - 6.4e-31 107.5 1.5 9.2e-31 106.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74474.1 - 2.1e-27 96.4 0.2 2.9e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74474.1 - 2.9e-12 46.6 0.2 4.5e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS74474.1 - 1.1e-05 25.0 0.1 2.5e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 ETS74474.1 - 0.0002 21.0 0.3 0.00084 19.0 0.1 2.2 2 0 0 2 2 2 1 PA domain Methyltransf_25 PF13649.1 ETS74474.1 - 0.031 14.6 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 ETS74474.1 - 0.032 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_S8 PF00082.17 ETS74475.1 - 1.8e-45 155.2 21.7 2.6e-45 154.7 15.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 ETS74475.1 - 4.2e-12 46.4 0.0 9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fungal_trans_2 PF11951.3 ETS74476.1 - 1.3e-31 109.5 2.0 1.9e-31 109.0 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74476.1 - 1.4e-10 40.8 11.5 2.3e-10 40.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 ETS74477.1 - 5e-17 60.5 13.0 1.1e-11 43.6 4.6 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS74477.1 - 2.6e-12 46.0 15.1 3.7e-09 36.0 4.5 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 ETS74477.1 - 1.3e-08 34.6 0.1 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.11 ETS74478.1 - 3.6e-20 71.9 51.0 6.7e-16 57.9 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myosin_tail_1 PF01576.14 ETS74479.1 - 0.00035 18.4 69.6 0.0077 14.0 1.5 3.4 2 1 1 3 3 3 3 Myosin tail GAS PF13851.1 ETS74479.1 - 0.00084 18.5 71.1 0.031 13.4 2.3 5.8 2 2 3 5 5 5 4 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETS74479.1 - 7.3 6.1 75.0 2.6 7.5 8.5 6.3 2 2 3 5 5 5 0 IncA protein Spermine_synth PF01564.12 ETS74480.1 - 1.3e-07 30.8 0.0 4.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 ETS74480.1 - 1.1e-06 28.5 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74480.1 - 0.0085 16.6 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74480.1 - 0.028 14.1 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74480.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS74480.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Secretin_N_2 PF07655.8 ETS74481.1 - 2.7 8.4 12.0 4.9 7.6 8.3 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain MRI PF15325.1 ETS74481.1 - 5.6 7.9 10.7 13 6.8 7.4 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection RAP1 PF07218.6 ETS74481.1 - 9.3 4.2 9.7 11 3.9 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Porin_4 PF13609.1 ETS74482.1 - 2.3 7.6 12.5 28 4.0 8.6 2.0 1 1 0 1 1 1 0 Gram-negative porin Rad10 PF03834.9 ETS74484.1 - 2e-30 104.2 0.0 3.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 ETS74484.1 - 0.0001 22.3 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Glyco_hydro_47 PF01532.15 ETS74485.1 - 2.2e-140 468.2 0.0 2.5e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1295 PF06966.7 ETS74486.1 - 5.6e-39 133.8 0.3 2.7e-37 128.2 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 ETS74486.1 - 0.17 11.9 1.1 0.35 11.0 0.0 2.1 3 0 0 3 3 3 0 Phospholipid methyltransferase FBPase PF00316.15 ETS74487.1 - 9.4e-122 405.8 0.0 1.1e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Peptidase_S10 PF00450.17 ETS74488.1 - 8.3e-75 252.5 0.0 2.3e-74 251.0 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS74488.1 - 0.0029 17.5 0.1 0.0071 16.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4001 PF13165.1 ETS74488.1 - 0.12 12.0 0.3 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) DUF3237 PF11578.3 ETS74490.1 - 5.2e-32 110.2 0.1 8.8e-32 109.4 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Acatn PF13000.2 ETS74490.1 - 0.028 12.9 0.1 0.031 12.7 0.1 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Sec3_C PF09763.4 ETS74491.1 - 2.7e-230 766.2 5.5 3.5e-230 765.8 3.8 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 ETS74491.1 - 1.6e-29 101.6 0.1 3.5e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 ETS74491.1 - 0.00048 20.1 1.1 0.009 16.1 0.0 3.4 4 0 0 4 4 4 1 Sec3 exocyst complex subunit DUF2408 PF10303.4 ETS74491.1 - 0.011 15.8 2.1 0.14 12.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) MutS_II PF05188.12 ETS74491.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 MutS domain II ARID PF01388.16 ETS74492.1 - 1.2e-14 53.9 0.0 3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.10 ETS74492.1 - 0.0035 17.4 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Arm PF00514.18 ETS74492.1 - 0.015 15.1 1.1 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SEN1_N PF12726.2 ETS74492.1 - 0.032 12.2 0.1 0.047 11.7 0.1 1.2 1 0 0 1 1 1 0 SEN1 N terminal HEAT_2 PF13646.1 ETS74492.1 - 0.11 12.8 0.2 3.2 8.0 0.2 2.9 2 1 1 3 3 3 0 HEAT repeats TFIIA PF03153.8 ETS74492.1 - 2.5 7.8 5.7 4 7.2 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.17 ETS74494.1 - 6.9e-15 55.5 0.0 3.1e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 ETS74494.1 - 0.00011 22.1 22.4 0.004 17.1 5.8 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 ETS74494.1 - 0.0024 18.1 0.0 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 ETS74494.1 - 0.0041 16.3 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS74494.1 - 0.015 15.4 0.0 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS74494.1 - 0.034 14.0 0.0 0.088 12.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS74494.1 - 0.051 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 ETS74494.1 - 0.065 12.3 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 ETS74494.1 - 0.14 12.4 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETS74494.1 - 0.15 11.5 0.0 0.44 9.9 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain zf-RING_2 PF13639.1 ETS74494.1 - 0.17 11.7 17.9 0.16 11.8 4.8 3.1 3 0 0 3 3 2 0 Ring finger domain AAA_29 PF13555.1 ETS74494.1 - 0.19 11.2 0.0 0.46 10.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC4 PF00097.20 ETS74494.1 - 0.27 10.9 19.5 0.083 12.5 4.8 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS74494.1 - 3.7 7.3 22.4 0.048 13.4 4.8 3.0 2 1 0 2 2 2 0 zinc-RING finger domain ZZ PF00569.12 ETS74494.1 - 9.7 5.8 12.9 1.3 8.6 5.7 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Atx10homo_assoc PF09759.4 ETS74495.1 - 2.9e-09 36.5 0.0 7.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain VIT1 PF01988.14 ETS74498.1 - 0.12 11.8 8.7 0.18 11.2 6.0 1.2 1 0 0 1 1 1 0 VIT family PrgI PF12666.2 ETS74498.1 - 2 8.5 4.9 3.6 7.8 3.4 1.5 1 0 0 1 1 1 0 PrgI family protein AMP-binding PF00501.23 ETS74499.1 - 8.6e-77 258.2 0.0 1.2e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS74499.1 - 6.5e-09 36.6 0.0 1.5e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cerato-platanin PF07249.7 ETS74500.1 - 5.9e-05 23.0 0.1 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 Cerato-platanin AA_permease_2 PF13520.1 ETS74501.1 - 6.5e-79 265.4 33.5 8.2e-79 265.1 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS74501.1 - 1.8e-18 66.1 28.7 2.6e-18 65.6 19.9 1.2 1 0 0 1 1 1 1 Amino acid permease CorA PF01544.13 ETS74502.1 - 0.024 13.6 4.3 0.021 13.8 1.4 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein EMP70 PF02990.11 ETS74502.1 - 0.048 12.1 0.1 0.071 11.5 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF1537 PF07005.6 ETS74503.1 - 5.1e-25 88.4 3.1 7e-25 88.0 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Fungal_trans PF04082.13 ETS74504.1 - 1.5e-08 33.8 1.8 1.5e-08 33.8 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain YgaB PF14182.1 ETS74504.1 - 0.25 11.6 2.3 1.7 8.9 0.1 2.9 3 0 0 3 3 3 0 YgaB-like protein MFS_1 PF07690.11 ETS74505.1 - 2.2e-33 115.4 32.3 2.2e-33 115.4 22.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SAF PF08666.7 ETS74506.1 - 4.2e-09 36.6 0.0 1.2e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 SAF domain NAD_binding_3 PF03447.11 ETS74506.1 - 5.5e-06 26.7 0.0 2.1e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 ETS74506.1 - 2.9e-05 24.5 0.1 8.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_N PF00044.19 ETS74506.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.23 ETS74508.1 - 5.2e-65 219.4 0.0 6.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS74508.1 - 5.9e-11 43.1 0.2 1.6e-10 41.7 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RHH_1 PF01402.16 ETS74508.1 - 0.097 12.6 0.3 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Hce2 PF14856.1 ETS74509.1 - 8.9e-15 54.3 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Epimerase PF01370.16 ETS74510.1 - 3.4e-18 65.9 0.1 4.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS74510.1 - 4.4e-14 52.9 0.0 6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS74510.1 - 4.3e-07 28.9 0.2 0.0035 16.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETS74510.1 - 1.2e-06 28.0 0.3 4.6e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 ETS74510.1 - 3.8e-05 23.6 1.2 5.9e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 ETS74510.1 - 0.00013 20.9 0.0 0.0019 17.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETS74510.1 - 0.052 12.4 0.1 0.91 8.3 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein KR PF08659.5 ETS74510.1 - 0.51 9.9 2.9 0.67 9.5 0.2 2.4 2 1 0 2 2 2 0 KR domain Zn_clus PF00172.13 ETS74511.1 - 0.0027 17.5 9.4 0.005 16.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS74512.1 - 2.4e-87 293.4 20.0 2.7e-87 293.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74512.1 - 8.5e-30 103.6 47.4 4.7e-27 94.6 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS74512.1 - 1.2 8.9 7.7 11 5.8 0.0 3.5 3 0 0 3 3 3 0 MFS_1 like family DUF3720 PF12517.3 ETS74514.1 - 0.014 16.0 3.6 0.019 15.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Pex24p PF06398.6 ETS74515.1 - 6.8e-102 340.9 0.6 8.4e-102 340.6 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PWWP PF00855.12 ETS74516.1 - 2.3e-06 27.7 0.5 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 PWWP domain Abhydrolase_6 PF12697.2 ETS74517.1 - 3.5e-24 85.9 0.0 4.2e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS74517.1 - 2.2e-15 56.8 0.0 3.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS74517.1 - 2.1e-08 34.0 0.0 6.4e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS74517.1 - 7e-06 24.7 0.0 1.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family FAT PF02259.18 ETS74518.1 - 2.1e-124 415.0 6.9 4.4e-124 414.0 4.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 ETS74518.1 - 2.4e-61 207.2 0.1 4e-61 206.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 ETS74518.1 - 2.4e-60 203.0 2.2 4e-59 199.1 0.2 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 ETS74518.1 - 8e-43 144.6 3.1 1e-42 144.2 0.0 3.0 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 ETS74518.1 - 1.4e-14 53.2 0.2 3.1e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 ETS74518.1 - 1.7e-14 53.8 11.3 0.0015 18.7 0.1 7.3 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.17 ETS74518.1 - 3.3e-12 45.4 15.3 0.091 12.8 0.0 10.4 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 ETS74518.1 - 4.5e-12 46.0 7.3 0.00073 19.9 0.0 9.8 7 2 2 9 9 8 2 HEAT-like repeat Adaptin_N PF01602.15 ETS74518.1 - 1.4e-06 26.9 1.6 1 7.5 0.0 5.0 3 1 1 4 4 4 3 Adaptin N terminal region UME PF08064.8 ETS74518.1 - 8.6e-06 25.6 0.6 1.4 8.8 0.0 5.6 5 1 0 5 5 5 2 UME (NUC010) domain Sec7_N PF12783.2 ETS74518.1 - 1.1 8.6 6.5 35 3.7 0.0 4.7 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Rtf2 PF04641.7 ETS74519.1 - 1.3e-50 172.0 5.5 1.5e-50 171.8 3.8 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 ETS74519.1 - 0.0014 18.2 0.0 0.0037 16.9 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 ETS74519.1 - 0.0072 16.0 0.1 0.015 14.9 0.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETS74519.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 ETS74519.1 - 0.093 12.4 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 ETS74519.1 - 1.4 8.6 4.6 7.1 6.4 0.6 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RR_TM4-6 PF06459.7 ETS74519.1 - 3 7.6 8.5 4.1 7.2 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 ETS74519.1 - 5.4 6.4 15.2 8.8 5.7 10.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PRKCSH-like PF12999.2 ETS74520.1 - 1.1e-38 132.5 13.2 9.8e-24 83.8 3.2 3.2 3 1 1 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 ETS74520.1 - 9.7e-30 103.0 1.5 9.7e-30 103.0 1.1 2.2 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 ETS74520.1 - 2.8e-12 47.2 2.0 9.4e-12 45.5 1.4 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Osmo_CC PF08946.5 ETS74520.1 - 0.0014 18.6 4.4 0.0051 16.8 3.1 2.1 1 0 0 1 1 1 1 Osmosensory transporter coiled coil DUF4200 PF13863.1 ETS74520.1 - 0.0047 16.8 14.8 0.0047 16.8 10.3 2.4 3 0 0 3 3 2 1 Domain of unknown function (DUF4200) TolA PF06519.6 ETS74520.1 - 0.011 15.6 0.0 0.041 13.8 0.0 1.9 2 0 0 2 2 1 0 TolA C-terminal V_ATPase_I PF01496.14 ETS74520.1 - 0.023 12.5 2.2 0.03 12.2 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ldl_recept_a PF00057.13 ETS74520.1 - 0.028 14.3 1.5 0.028 14.3 1.1 2.4 2 0 0 2 2 1 0 Low-density lipoprotein receptor domain class A CASP_C PF08172.7 ETS74520.1 - 0.063 12.2 3.1 0.12 11.4 2.1 1.3 1 0 0 1 1 1 0 CASP C terminal Vps5 PF09325.5 ETS74520.1 - 0.096 11.9 7.4 0.26 10.4 4.4 2.1 2 0 0 2 2 2 0 Vps5 C terminal like APG6 PF04111.7 ETS74520.1 - 0.17 10.8 5.2 0.44 9.5 3.6 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Effector_1 PF04518.7 ETS74520.1 - 0.24 10.3 2.0 0.23 10.4 0.5 1.6 2 0 0 2 2 2 0 Effector from type III secretion system Filament PF00038.16 ETS74520.1 - 0.47 9.8 16.9 0.64 9.4 5.6 2.3 1 1 1 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.4 ETS74520.1 - 0.69 9.7 9.4 0.68 9.7 5.1 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain IncA PF04156.9 ETS74520.1 - 0.86 9.1 9.6 1.8 8.1 5.9 2.0 2 0 0 2 2 2 0 IncA protein DUF3373 PF11853.3 ETS74520.1 - 1.1 7.6 6.6 0.22 10.0 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Prefoldin_2 PF01920.15 ETS74520.1 - 1.7 8.4 16.6 0.036 13.8 4.9 3.0 3 1 0 3 3 3 0 Prefoldin subunit Fmp27_WPPW PF10359.4 ETS74520.1 - 1.7 6.9 10.0 0.21 9.9 4.1 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Syntaxin_2 PF14523.1 ETS74520.1 - 2.4 8.2 9.0 0.44 10.6 3.1 2.1 2 0 0 2 2 1 0 Syntaxin-like protein Macoilin PF09726.4 ETS74520.1 - 2.9 6.0 10.6 6.9 4.8 7.4 1.5 1 0 0 1 1 1 0 Transmembrane protein TMPIT PF07851.8 ETS74520.1 - 4.1 6.3 5.5 6.5 5.7 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 ETS74520.1 - 4.5 7.3 8.7 8.2 6.5 2.6 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 ETS74520.1 - 5.9 7.2 9.9 84 3.5 5.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 ETS74520.1 - 9.2 5.3 11.5 17 4.4 8.0 1.4 1 0 0 1 1 1 0 TMCO5 family PHO4 PF01384.15 ETS74521.1 - 7.8e-101 336.9 21.4 1.1e-100 336.4 14.8 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF486 PF04342.7 ETS74521.1 - 0.058 13.4 0.1 0.058 13.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF486 Gin PF10764.4 ETS74522.1 - 0.071 12.8 0.5 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-met2 PF12907.2 ETS74522.1 - 0.11 12.4 0.4 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc-binding Vint PF14623.1 ETS74523.1 - 2.4e-42 144.1 0.0 4e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Hint-domain VWA_2 PF13519.1 ETS74523.1 - 9.7e-23 81.1 0.0 2.6e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Vwaint PF14624.1 ETS74523.1 - 7.3e-22 77.2 0.0 1.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.23 ETS74523.1 - 1.4e-16 60.6 0.0 2.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETS74523.1 - 8.8e-13 48.2 0.1 6e-11 42.2 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain HATPase_c PF02518.21 ETS74524.1 - 6.1e-23 80.6 0.0 1.9e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS74524.1 - 9.8e-23 80.3 0.3 2.7e-22 78.8 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 ETS74524.1 - 4.9e-11 42.9 0.0 0.00035 20.9 0.0 3.9 3 1 0 3 3 3 3 PAS domain PAS_4 PF08448.5 ETS74524.1 - 2.6e-09 37.0 0.0 0.051 13.6 0.0 3.7 3 1 0 3 3 3 3 PAS fold HisKA PF00512.20 ETS74524.1 - 3e-08 33.5 0.1 2.7e-07 30.4 0.1 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 ETS74524.1 - 3.5e-07 29.8 0.0 0.02 14.7 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 ETS74524.1 - 4.6e-05 23.4 0.1 0.00076 19.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 ETS74524.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain DUF2217 PF10265.4 ETS74525.1 - 2 7.0 3.7 6.6 5.3 2.6 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FR47 PF08445.5 ETS74526.1 - 0.00021 20.9 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 ETS74526.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS74526.1 - 0.00096 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS74526.1 - 0.0016 18.5 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS74526.1 - 0.012 15.7 0.1 0.03 14.4 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS74526.1 - 0.052 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 ETS74527.1 - 0.00079 18.9 0.2 0.0024 17.4 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase EamA PF00892.15 ETS74528.1 - 2.2e-23 82.6 33.1 2e-13 50.4 9.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 ETS74528.1 - 0.0058 16.8 27.8 0.036 14.2 4.0 3.1 2 2 1 3 3 3 2 Multidrug resistance efflux transporter NADH-u_ox-rdase PF10785.4 ETS74528.1 - 0.52 10.5 3.2 54 4.1 0.0 4.2 3 2 1 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TPT PF03151.11 ETS74528.1 - 7.4 6.2 18.8 1.7 8.2 7.7 2.9 2 2 0 2 2 2 0 Triose-phosphate Transporter family ABC2_membrane PF01061.19 ETS74529.1 - 1.3e-95 318.5 64.1 2.5e-50 170.5 14.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 ETS74529.1 - 9e-40 134.5 4.5 5.7e-32 109.4 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 ETS74529.1 - 5.4e-34 117.4 0.0 3.5e-16 59.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 ETS74529.1 - 1.3e-17 63.6 0.0 3.6e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS74529.1 - 5.9e-09 35.5 0.4 1.7e-05 24.2 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS74529.1 - 2.5e-07 30.6 0.1 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS74529.1 - 9.8e-07 28.9 0.5 3.7e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETS74529.1 - 5.2e-06 25.8 0.9 0.0012 18.2 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETS74529.1 - 1.6e-05 24.1 0.0 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS74529.1 - 2.3e-05 25.1 0.0 0.12 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 ETS74529.1 - 0.00011 21.7 0.5 0.0037 16.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 ETS74529.1 - 0.00033 20.9 0.1 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETS74529.1 - 0.00052 20.0 0.2 0.29 11.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 ETS74529.1 - 0.00063 19.8 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETS74529.1 - 0.001 18.3 0.0 2.1 7.5 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 ETS74529.1 - 0.002 17.8 0.4 2.4 7.9 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 ETS74529.1 - 0.0021 17.7 0.1 0.46 10.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 ETS74529.1 - 0.011 15.6 0.4 0.2 11.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 ETS74529.1 - 0.012 15.8 0.2 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 ETS74529.1 - 0.025 15.0 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 ETS74529.1 - 0.029 13.9 0.3 0.54 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS74529.1 - 0.036 13.6 0.5 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 ETS74529.1 - 0.099 12.0 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 ETS74529.1 - 0.1 12.8 0.8 0.21 11.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 ETS74529.1 - 0.12 12.3 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 ETS74529.1 - 0.2 11.5 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS74529.1 - 0.22 11.2 0.0 7.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 ETS74529.1 - 0.33 9.8 0.1 9.3 5.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 ETS74529.1 - 0.36 10.2 2.0 8.9 5.6 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain NTPase_1 PF03266.10 ETS74529.1 - 0.37 10.5 0.5 15 5.2 0.1 2.8 3 0 0 3 3 3 0 NTPase ABC2_membrane_3 PF12698.2 ETS74529.1 - 3.6 6.5 55.8 0.15 11.0 11.5 4.1 3 2 1 4 4 4 0 ABC-2 family transporter protein Fib_alpha PF08702.5 ETS74531.1 - 0.00058 20.0 2.6 0.0012 18.9 1.8 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family SlyX PF04102.7 ETS74531.1 - 0.00082 19.6 11.4 0.066 13.6 0.8 2.9 1 1 1 2 2 2 2 SlyX ATG16 PF08614.6 ETS74531.1 - 0.0033 17.2 8.6 0.16 11.7 3.0 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 ETS74531.1 - 0.013 14.7 1.5 0.013 14.7 1.0 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med9 PF07544.8 ETS74531.1 - 0.023 14.4 6.0 4 7.2 0.0 3.1 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.1 ETS74531.1 - 0.025 14.6 4.6 0.049 13.6 3.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 ETS74531.1 - 0.063 12.8 7.0 0.13 11.8 4.9 1.5 1 0 0 1 1 1 0 IncA protein DASH_Spc34 PF08657.5 ETS74531.1 - 0.066 12.8 3.1 0.1 12.2 2.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 KxDL PF10241.4 ETS74531.1 - 0.089 12.7 3.1 3 7.8 0.9 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein APG6 PF04111.7 ETS74531.1 - 0.16 10.9 2.3 0.24 10.3 1.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 ETS74531.1 - 0.21 10.0 0.9 0.29 9.5 0.6 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 ETS74531.1 - 0.52 10.1 9.2 0.65 9.8 4.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 ETS74531.1 - 0.57 9.3 6.0 0.33 10.1 2.2 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.1 ETS74531.1 - 0.67 9.0 7.2 1 8.4 5.0 1.2 1 0 0 1 1 1 0 TMCO5 family DUF2968 PF11180.3 ETS74531.1 - 0.7 9.2 13.2 1.2 8.4 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NPV_P10 PF05531.7 ETS74531.1 - 0.71 10.1 9.1 20 5.5 5.1 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.15 ETS74531.1 - 0.93 9.2 8.5 3.6 7.3 3.1 2.6 1 1 2 3 3 3 0 Prefoldin subunit DUF724 PF05266.9 ETS74531.1 - 0.97 9.0 5.1 1.2 8.7 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) RBD-FIP PF09457.5 ETS74531.1 - 0.97 9.2 4.3 23 4.8 0.4 2.8 2 1 1 3 3 3 0 FIP domain ADIP PF11559.3 ETS74531.1 - 1.3 8.8 8.8 1.7 8.5 5.0 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 ETS74531.1 - 1.7 8.9 7.0 11 6.3 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 ETS74531.1 - 1.8 8.7 5.9 14 5.8 2.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 ETS74531.1 - 3.9 7.0 12.3 14 5.2 5.9 2.4 1 1 0 2 2 2 0 Septum formation initiator Fungal_trans PF04082.13 ETS74532.1 - 1e-33 116.3 0.0 2.1e-33 115.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74532.1 - 9.7e-09 35.0 14.1 1.7e-08 34.2 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YjgF_endoribonc PF14588.1 ETS74532.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Imm_superinfect PF14373.1 ETS74533.1 - 0.17 11.5 2.7 0.45 10.1 1.9 1.7 1 0 0 1 1 1 0 Superinfection immunity protein DUF1996 PF09362.5 ETS74534.1 - 3.4e-76 256.0 3.5 5.1e-76 255.4 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pex16 PF08610.5 ETS74535.1 - 7e-105 350.7 1.3 8.5e-105 350.4 0.9 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.15 ETS74535.1 - 0.041 14.2 0.5 5.8 7.3 0.1 2.6 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus NUDIX PF00293.23 ETS74536.1 - 6.9e-11 41.9 0.1 1.1e-10 41.2 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain SWIRM PF04433.12 ETS74537.1 - 1.4e-13 50.7 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain adh_short PF00106.20 ETS74538.1 - 4.7e-23 81.9 0.4 6.8e-22 78.1 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74538.1 - 2.3e-18 66.8 0.5 3.7e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74538.1 - 3.4e-09 36.6 0.3 1.1e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 ETS74538.1 - 6.4e-06 26.3 0.1 1.1e-05 25.5 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 ETS74538.1 - 0.0076 16.2 0.9 0.046 13.7 0.4 2.2 2 1 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 ETS74538.1 - 0.0095 15.4 0.2 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 ETS74538.1 - 0.015 14.2 0.1 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1776 PF08643.5 ETS74538.1 - 0.036 13.1 0.0 0.095 11.8 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) AAA PF00004.24 ETS74539.1 - 1.5e-17 64.0 0.0 7e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS74539.1 - 1.2e-05 25.4 0.3 0.00084 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS74539.1 - 0.00052 19.7 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 ETS74539.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS74539.1 - 0.0045 17.0 0.7 0.03 14.3 0.5 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 ETS74539.1 - 0.012 15.0 0.1 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS74539.1 - 0.03 14.1 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 ETS74539.1 - 0.042 12.8 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETS74539.1 - 0.055 13.7 0.3 0.67 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 ETS74539.1 - 0.076 13.8 1.2 0.31 11.8 0.0 2.7 3 1 0 3 3 3 0 AAA domain Zot PF05707.7 ETS74539.1 - 0.1 12.0 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Abhydrolase_5 PF12695.2 ETS74540.1 - 2.6e-06 27.2 0.0 5.5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS74540.1 - 0.0003 20.4 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS74540.1 - 0.00095 18.4 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 ETS74540.1 - 0.001 17.6 0.0 0.007 14.9 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 ETS74540.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 ETS74540.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Pro-kuma_activ PF09286.6 ETS74541.1 - 4.7e-38 130.4 0.0 8.2e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS74541.1 - 2.6e-07 30.0 0.4 4.5e-07 29.3 0.3 1.3 1 0 0 1 1 1 1 Subtilase family SpoU_methylase PF00588.14 ETS74542.1 - 6.2e-28 97.4 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 ETS74542.1 - 5.3e-06 26.5 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 ETS74543.1 - 3.9e-68 228.1 9.5 7.8e-68 227.1 6.6 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 ETS74543.1 - 1.3e-57 194.9 0.0 1.9e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS74543.1 - 2.7e-14 52.7 0.0 6.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETS74543.1 - 1.1e-11 44.1 0.4 2.5e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 ETS74543.1 - 6.6e-07 28.9 15.3 0.0023 17.5 3.5 3.3 2 1 1 3 3 3 2 PHD-finger Chromo PF00385.19 ETS74543.1 - 0.0049 16.5 0.2 0.0049 16.5 0.1 3.7 5 0 0 5 5 5 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 ETS74543.1 - 0.0054 16.5 0.0 0.097 12.4 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_1 PF14446.1 ETS74543.1 - 0.043 13.5 6.1 0.04 13.6 1.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.9 ETS74543.1 - 0.62 9.7 4.3 2.6 7.7 0.1 3.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid SnAC PF14619.1 ETS74543.1 - 3.2 7.9 10.5 0.28 11.3 1.7 3.4 4 0 0 4 4 4 0 Snf2-ATP coupling, chromatin remodelling complex DUF342 PF03961.8 ETS74545.1 - 0.0091 14.4 5.8 0.018 13.4 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF342) HeLo PF14479.1 ETS74545.1 - 0.063 13.0 7.3 0.19 11.4 5.0 1.8 1 0 0 1 1 1 0 Prion-inhibition and propagation Z1 PF10593.4 ETS74545.1 - 0.12 11.5 5.3 0.21 10.7 3.7 1.4 1 0 0 1 1 1 0 Z1 domain SPX PF03105.14 ETS74545.1 - 0.29 10.8 13.6 0.13 12.0 7.3 2.0 2 0 0 2 2 2 0 SPX domain LMBR1 PF04791.11 ETS74545.1 - 1.9 6.9 7.6 2.6 6.5 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 ETS74545.1 - 2.5 5.8 12.5 0.71 7.6 6.5 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 ETS74545.1 - 7.7 5.7 15.2 17 4.6 10.5 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L7Ae PF01248.21 ETS74546.1 - 6.4e-25 86.4 0.0 7.3e-25 86.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 ETS74547.1 - 2.1e-31 108.4 0.1 2.8e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3176 PF11374.3 ETS74549.1 - 4.6e-18 65.1 6.0 1.4e-17 63.5 0.5 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) p450 PF00067.17 ETS74550.1 - 2.5e-45 154.8 0.0 3.5e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 ETS74551.1 - 1.3e-06 28.1 12.9 2.2e-06 27.4 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS74551.1 - 2.4e-05 23.1 1.5 0.00013 20.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain HR1 PF02185.11 ETS74552.1 - 0.22 11.3 0.5 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Hr1 repeat Pro_isomerase PF00160.16 ETS74553.1 - 6e-45 153.2 0.2 1e-44 152.5 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 ETS74553.1 - 9.3e-10 38.0 6.6 2.5e-05 23.8 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETS74553.1 - 1.1e-08 34.2 3.6 2e-06 27.2 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS74553.1 - 1.6e-06 27.4 1.9 5.3e-06 25.8 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS74553.1 - 6.4e-06 25.5 0.3 3.3e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS74553.1 - 0.00044 20.1 1.5 0.00076 19.3 0.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS74553.1 - 0.00096 19.4 1.0 0.0042 17.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS74553.1 - 0.0022 18.6 4.2 0.0022 18.6 2.9 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS74553.1 - 0.012 16.1 0.4 0.012 16.1 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RasGAP PF00616.14 ETS74554.1 - 5.9e-43 146.8 0.0 8.3e-41 139.8 0.0 2.5 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 ETS74554.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain Sororin PF09666.5 ETS74555.1 - 0.00076 19.7 2.6 0.0029 17.8 1.8 2.0 1 0 0 1 1 1 1 Sororin protein MRP-L20 PF12824.2 ETS74556.1 - 1.4e-53 181.2 3.2 1.6e-53 181.0 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 ETS74556.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Neugrin Hyccin PF09790.4 ETS74556.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Hyccin FYVE PF01363.16 ETS74557.1 - 9.2 6.2 17.6 0.12 12.3 6.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger Glyco_trans_2_3 PF13632.1 ETS74558.1 - 1.4e-44 152.1 2.3 3.7e-44 150.7 1.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS74558.1 - 5.4e-07 29.6 0.0 9.6e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS74558.1 - 9e-06 25.4 0.0 0.00056 19.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS74558.1 - 0.0072 15.6 0.0 0.026 13.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Trehalase PF01204.13 ETS74559.1 - 3.1e-188 626.5 0.0 4.1e-188 626.1 0.0 1.2 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 ETS74559.1 - 8.1e-17 60.2 0.8 1.3e-16 59.5 0.5 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 ETS74560.1 - 4.2e-284 942.6 0.6 4.7e-284 942.4 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS74560.1 - 4.6e-12 45.6 0.0 3.4e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Sugar_tr PF00083.19 ETS74561.1 - 8.9e-97 324.4 22.1 1e-96 324.2 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74561.1 - 2.2e-26 92.3 32.6 3e-21 75.5 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF946 PF06101.6 ETS74562.1 - 9.4e-11 40.3 1.0 1.5e-10 39.6 0.2 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) Caps_synth PF05704.7 ETS74563.1 - 1e-10 41.2 0.0 2.6e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 ETS74563.1 - 0.0062 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ank_2 PF12796.2 ETS74564.1 - 7.4e-07 29.4 0.0 0.00014 22.0 0.0 3.3 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS74564.1 - 3.2e-05 24.0 0.5 0.019 15.1 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS74564.1 - 4.4e-05 23.0 0.0 0.003 17.2 0.0 3.5 4 1 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETS74564.1 - 6.3e-05 23.3 0.0 3.2 8.3 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74564.1 - 0.0011 18.9 0.0 0.036 14.3 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 ETS74565.1 - 5.7e-20 71.4 0.0 9e-08 32.3 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS74565.1 - 1.8e-15 55.4 0.0 0.016 15.3 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.25 ETS74565.1 - 2.9e-12 45.7 0.0 0.1 12.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS74565.1 - 6.4e-11 42.4 0.1 0.002 18.5 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS74565.1 - 9.8e-08 32.0 0.1 0.01 16.0 0.0 4.3 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS74566.1 - 2.2e-08 34.3 0.0 0.00024 21.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74566.1 - 0.00072 19.2 0.0 30 4.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 ETS74566.1 - 0.0008 19.5 0.0 11 6.3 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS74566.1 - 0.034 14.6 0.3 27 5.4 0.0 4.2 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS74567.1 - 3.5e-23 81.7 0.4 3.1e-10 40.2 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74567.1 - 1.6e-20 71.8 2.2 0.0002 21.0 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 ETS74567.1 - 1.4e-18 65.0 1.7 0.0042 17.1 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 ETS74567.1 - 1.2e-16 60.6 1.4 0.00019 21.8 0.0 6.3 4 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS74567.1 - 7.8e-14 51.3 5.0 0.00015 21.8 0.0 5.9 3 2 3 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.2 ETS74567.1 - 0.0007 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like Filament PF00038.16 ETS74570.1 - 0.00037 20.0 37.3 0.00064 19.2 25.8 1.3 1 0 0 1 1 1 1 Intermediate filament protein MerR-DNA-bind PF09278.6 ETS74570.1 - 0.0044 17.3 3.1 0.065 13.6 1.5 3.4 2 1 0 2 2 2 1 MerR, DNA binding Reo_sigmaC PF04582.7 ETS74570.1 - 0.13 11.3 5.4 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Ank_2 PF12796.2 ETS74573.1 - 2.7e-19 69.3 7.1 2.6e-11 43.7 1.4 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS74573.1 - 3e-13 49.5 3.1 2.2e-05 24.5 0.3 4.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS74573.1 - 6.6e-13 47.7 9.2 1.6e-05 24.4 0.4 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 ETS74573.1 - 6.3e-10 39.3 3.3 8.8e-05 22.9 0.1 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74573.1 - 1.3e-09 37.3 6.4 0.0022 18.0 0.2 5.4 6 0 0 6 6 6 3 Ankyrin repeat F-box-like PF12937.2 ETS74573.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.2 ETS74574.1 - 7.2e-19 67.9 0.0 1.1e-08 35.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74574.1 - 6.4e-14 50.9 1.1 0.0017 18.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS74574.1 - 9.6e-12 45.0 3.0 0.00015 22.1 0.0 5.6 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS74574.1 - 2.4e-11 43.4 0.9 0.00079 19.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74574.1 - 7.2e-09 35.0 1.8 0.15 12.4 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat F-box-like PF12937.2 ETS74574.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like FAD_binding_3 PF01494.14 ETS74575.1 - 2.9e-28 98.9 0.1 1.3e-27 96.8 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS74575.1 - 2.7e-11 42.9 2.9 2e-05 23.6 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS74575.1 - 2.4e-07 29.9 2.2 6.9e-07 28.5 0.7 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS74575.1 - 1.9e-05 24.8 0.2 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS74575.1 - 3.3e-05 23.1 0.7 0.0052 15.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS74575.1 - 8.5e-05 22.4 0.6 0.00025 21.0 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS74575.1 - 0.0016 18.7 1.1 0.018 15.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS74575.1 - 0.0018 17.4 0.1 0.0031 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ETS74575.1 - 0.0034 16.0 1.6 0.023 13.3 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS74575.1 - 0.0046 16.8 2.0 0.04 13.7 1.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS74575.1 - 0.0054 16.5 3.9 0.87 9.3 0.1 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS74575.1 - 0.023 13.5 1.4 0.044 12.6 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 ETS74575.1 - 0.043 12.2 0.2 2.9 6.2 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 ETS74575.1 - 0.052 12.6 0.4 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Cupin_2 PF07883.6 ETS74576.1 - 3e-15 55.4 0.1 4e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS74576.1 - 7.2e-11 41.7 0.0 9e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 ETS74576.1 - 0.0007 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS74576.1 - 0.0048 16.5 0.1 0.0074 15.9 0.0 1.3 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 ETS74576.1 - 0.011 15.4 0.2 0.015 14.8 0.1 1.3 1 1 0 1 1 1 0 Cupin GPI PF06560.6 ETS74576.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Endosulfine PF04667.12 ETS74577.1 - 6.6e-21 74.0 0.1 1.3e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.8 ETS74578.1 - 2e-121 405.2 0.0 2.3e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.1 ETS74579.1 - 4.4e-52 177.4 7.0 2.1e-28 99.9 3.0 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling RNA_Me_trans PF04252.8 ETS74580.1 - 2.4e-48 164.1 0.0 2.8e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.20 ETS74581.1 - 8.5e-05 21.8 0.0 0.00039 19.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Trypan_PARP PF05887.6 ETS74581.1 - 0.0076 16.0 15.7 0.0076 16.0 10.9 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF605 PF04652.11 ETS74581.1 - 1.8 7.8 15.8 2.9 7.2 11.0 1.2 1 0 0 1 1 1 0 Vta1 like Vac7 PF12751.2 ETS74582.1 - 2.9e-113 378.6 9.1 2.2e-101 339.5 0.8 2.6 2 0 0 2 2 2 2 Vacuolar segregation subunit 7 PRP1_N PF06424.7 ETS74583.1 - 2.1e-52 176.9 6.2 2.1e-52 176.9 4.3 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 ETS74583.1 - 1.6e-37 124.5 34.4 0.00011 22.5 0.2 13.8 6 4 9 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 ETS74583.1 - 9.5e-28 96.3 14.7 5.6e-09 36.2 0.1 9.7 7 3 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS74583.1 - 1.3e-26 92.6 20.1 2e-08 34.7 0.2 8.9 5 2 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETS74583.1 - 1.5e-15 56.5 8.8 0.05 13.2 0.0 8.5 6 2 4 10 10 10 6 TPR repeat TPR_2 PF07719.12 ETS74583.1 - 2.5e-13 48.8 11.1 0.23 11.4 0.0 11.0 12 1 1 13 13 12 2 Tetratricopeptide repeat NARP1 PF12569.3 ETS74583.1 - 2.3e-10 39.8 2.5 0.058 12.1 0.0 6.4 5 1 2 7 7 7 3 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 ETS74583.1 - 3.4e-10 39.3 3.1 8.1 6.9 0.1 10.2 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_15 PF13429.1 ETS74583.1 - 6.2e-09 35.3 22.9 7e-06 25.2 2.9 6.4 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS74583.1 - 8.9e-08 31.3 0.0 11 6.0 0.0 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS74583.1 - 1.9e-06 27.9 7.6 18 6.0 0.0 9.2 10 0 0 10 10 9 0 Tetratricopeptide repeat Suf PF05843.9 ETS74583.1 - 7.5e-05 22.5 0.0 0.68 9.6 0.0 4.3 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_7 PF13176.1 ETS74583.1 - 0.00011 21.7 3.4 2.1 8.3 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS74583.1 - 0.00012 22.1 0.1 0.63 10.2 0.0 5.3 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETS74583.1 - 0.00018 21.3 14.7 0.27 11.2 0.0 8.0 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS74583.1 - 0.0065 16.0 0.1 5.4 6.7 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETS74583.1 - 0.0095 15.8 0.7 0.0095 15.8 0.5 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS74583.1 - 1.4 8.9 10.4 52 3.9 0.2 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.5 ETS74583.1 - 4.4 5.9 6.1 23 3.5 0.1 3.6 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Fungal_trans PF04082.13 ETS74584.1 - 2e-27 95.7 0.4 3.1e-27 95.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74584.1 - 3.8e-06 26.7 13.9 6.5e-06 25.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS74585.1 - 2.3e-70 237.4 26.3 2.7e-70 237.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74585.1 - 9.1e-32 110.1 24.2 9.1e-32 110.1 16.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS74585.1 - 1.3e-07 30.2 3.2 1.3e-07 30.2 2.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 ETS74585.1 - 4.9e-07 28.7 0.5 4.9e-07 28.7 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF791) BT1 PF03092.11 ETS74585.1 - 0.0015 17.2 5.3 0.017 13.8 3.5 2.1 1 1 0 1 1 1 1 BT1 family Bromo_TP PF07524.8 ETS74585.1 - 0.04 13.6 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Bromodomain associated DUF1479 PF07350.7 ETS74586.1 - 6.3e-114 380.6 0.0 7.6e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Amidase PF01425.16 ETS74587.1 - 3.8e-80 269.9 0.4 9.6e-80 268.5 0.3 1.6 1 1 0 1 1 1 1 Amidase NAD_binding_10 PF13460.1 ETS74587.1 - 3.2e-12 46.8 0.1 1.2e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS74587.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS74587.1 - 2.8e-10 39.3 0.0 5.6e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETS74587.1 - 0.01 15.1 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 ETS74587.1 - 0.024 14.5 0.1 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.10 ETS74587.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amidase PF01425.16 ETS74588.1 - 1.9e-94 317.0 0.0 2.4e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.17 ETS74589.1 - 2.3e-28 98.9 0.0 3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 ETS74590.1 - 6.2e-82 275.4 29.9 7.2e-82 275.2 20.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pmp3 PF01679.12 ETS74590.1 - 0.016 14.8 2.3 0.016 14.8 1.6 2.7 3 0 0 3 3 3 0 Proteolipid membrane potential modulator MerC PF03203.9 ETS74590.1 - 2.9 8.3 14.4 4.7 7.6 2.5 3.7 3 0 0 3 3 3 0 MerC mercury resistance protein Fungal_trans PF04082.13 ETS74591.1 - 7.5e-15 54.5 0.1 1.3e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0515 PF15135.1 ETS74591.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 TPMT PF05724.6 ETS74591.1 - 0.073 12.4 0.1 0.18 11.2 0.1 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.17 ETS74592.1 - 6.8e-54 183.1 0.0 8.2e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 ETS74593.1 - 7.9e-23 81.4 0.3 2.2e-22 80.0 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS74593.1 - 2.7e-22 79.4 3.0 2.6e-21 76.2 2.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74593.1 - 2.3e-10 40.4 2.6 1.4e-08 34.5 0.0 2.1 1 1 0 2 2 2 2 KR domain Abhydrolase_6 PF12697.2 ETS74594.1 - 1.2e-16 61.2 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS74594.1 - 6.7e-15 55.2 0.2 1e-12 48.1 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS74594.1 - 1.1e-05 25.2 0.0 9.6e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribonuc_L-PSP PF01042.16 ETS74595.1 - 1e-18 67.2 0.0 1.4e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Prenyltrans_1 PF13243.1 ETS74595.1 - 0.056 13.4 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 Prenyltransferase-like Peptidase_M20 PF01546.23 ETS74596.1 - 1.8e-33 115.6 0.0 3.9e-33 114.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS74596.1 - 2.6e-14 52.9 0.0 4.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF605 PF04652.11 ETS74597.1 - 9.6 5.4 25.2 0.59 9.4 8.7 2.1 2 0 0 2 2 2 0 Vta1 like Apolipoprotein PF01442.13 ETS74598.1 - 0.0001 21.9 2.6 0.00014 21.4 1.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4407 PF14362.1 ETS74598.1 - 0.0076 15.2 4.8 0.0089 15.0 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Vps51 PF08700.6 ETS74598.1 - 0.093 12.5 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Vps51/Vps67 OmpH PF03938.9 ETS74598.1 - 0.55 10.1 10.2 0.77 9.6 7.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2514 PF10721.4 ETS74598.1 - 1.2 8.7 12.2 1.9 8.1 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Borrelia_P83 PF05262.6 ETS74598.1 - 2.7 6.1 12.9 3.4 5.8 8.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.8 ETS74598.1 - 4 7.9 9.0 19 5.7 6.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FliE PF02049.13 ETS74598.1 - 4.5 7.3 7.3 1.4 9.0 2.3 2.0 1 1 2 3 3 3 0 Flagellar hook-basal body complex protein FliE RrnaAD PF00398.15 ETS74599.1 - 1.2e-56 191.6 0.0 1.7e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 ETS74599.1 - 1.5e-10 41.0 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74599.1 - 2e-08 34.8 0.0 5.2e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74599.1 - 2.7e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74599.1 - 0.00013 22.3 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS74599.1 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 ETS74599.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 ETS74599.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS74599.1 - 0.00045 19.6 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS74599.1 - 0.00047 19.3 0.0 0.00076 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS74599.1 - 0.002 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS74599.1 - 0.0053 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 ETS74599.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 ETS74599.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 ETS74599.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 ETS74599.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF43 PF01861.11 ETS74599.1 - 0.05 12.5 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Met_10 PF02475.11 ETS74599.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RuvB_N PF05496.7 ETS74599.1 - 0.13 11.3 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PPR PF01535.15 ETS74600.1 - 0.0032 17.3 0.7 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 ETS74600.1 - 0.015 15.2 0.0 0.73 9.8 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family PPR_3 PF13812.1 ETS74600.1 - 0.021 15.0 0.1 26 5.4 0.0 4.5 5 0 0 5 5 5 0 Pentatricopeptide repeat domain PP2C PF00481.16 ETS74601.1 - 8e-82 274.4 0.1 1.2e-81 273.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 ETS74601.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.7 ETS74602.1 - 8.7e-11 41.6 4.5 0.0098 15.9 0.1 4.2 3 1 0 3 3 3 3 Putative Ig domain Herpes_gE PF02480.11 ETS74602.1 - 1.5e-06 26.7 0.3 2.8e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 ETS74602.1 - 0.00013 21.2 3.4 0.00032 19.9 2.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 ETS74602.1 - 0.0006 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 ETS74602.1 - 0.0019 17.8 0.3 0.0056 16.3 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 ETS74602.1 - 0.0053 16.2 1.7 0.013 14.9 1.2 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 ETS74602.1 - 0.0056 16.3 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family Sarcoglycan_2 PF05510.8 ETS74602.1 - 0.0067 14.7 0.0 0.11 10.7 0.0 2.2 2 0 0 2 2 2 1 Sarcoglycan alpha/epsilon Shisa PF13908.1 ETS74602.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Methyltransf_16 PF10294.4 ETS74603.1 - 9.5e-45 152.1 0.0 1.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 ETS74603.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 ETS74603.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74603.1 - 0.087 13.4 0.1 0.17 12.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Zn_Tnp_IS1 PF03811.8 ETS74604.1 - 0.018 14.5 0.2 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 InsA N-terminal domain Abhydrolase_6 PF12697.2 ETS74605.1 - 1e-13 51.7 3.6 1.3e-13 51.4 2.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74605.1 - 4.1e-11 42.8 0.1 5.1e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PHB_acc PF05233.8 ETS74605.1 - 0.049 13.3 0.2 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain PGAP1 PF07819.8 ETS74605.1 - 0.07 12.7 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein DUF3433 PF11915.3 ETS74606.1 - 1.4e-45 153.3 18.1 1.3e-25 89.3 0.5 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) TRP PF06011.7 ETS74607.1 - 6.8e-148 492.8 32.4 8.3e-148 492.5 22.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 ETS74607.1 - 4.8e-45 153.0 1.5 8e-45 152.3 1.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 ETS74607.1 - 0.00027 21.1 0.2 0.00047 20.4 0.1 1.4 1 0 0 1 1 1 1 ML domain GTP_CH_N PF12471.3 ETS74607.1 - 0.028 14.0 0.1 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal DUF1510 PF07423.6 ETS74607.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 ETS74607.1 - 0.6 10.1 1.9 15 5.7 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1712 PF08217.6 ETS74608.1 - 3.8e-13 48.5 0.0 9.9e-09 33.9 0.0 3.1 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Cript PF10235.4 ETS74609.1 - 0.0028 17.9 2.7 0.0037 17.5 0.1 2.0 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Pec_lyase_C PF00544.14 ETS74610.1 - 6.8e-45 153.0 5.9 1e-44 152.4 4.1 1.2 1 0 0 1 1 1 1 Pectate lyase HpcH_HpaI PF03328.9 ETS74612.1 - 2.4e-30 105.0 0.0 2.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 ETS74612.1 - 0.00059 18.8 0.3 0.019 13.8 0.2 2.8 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain C-C_Bond_Lyase PF15617.1 ETS74612.1 - 0.063 12.0 0.0 0.14 10.9 0.0 1.6 1 1 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Iso_dh PF00180.15 ETS74613.1 - 2.7e-73 246.9 0.0 3.2e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_3 PF00933.16 ETS74614.1 - 4.2e-86 288.6 0.0 6e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS74614.1 - 3.3e-42 144.5 0.2 4.2e-41 140.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS74614.1 - 5.6e-25 87.0 0.0 1.1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Patatin PF01734.17 ETS74615.1 - 9.5e-27 94.2 0.0 2.9e-26 92.6 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_11 PF13414.1 ETS74615.1 - 0.0054 16.3 0.4 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 TPR repeat Sina PF03145.11 ETS74617.1 - 0.079 12.6 4.6 0.12 11.9 3.2 1.3 1 0 0 1 1 1 0 Seven in absentia protein family Tnp_zf-ribbon_2 PF13842.1 ETS74617.1 - 0.91 9.9 7.5 2.9 8.3 5.2 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon TFIIIC_sub6 PF10419.4 ETS74618.1 - 5.7e-12 44.8 0.0 9.4e-12 44.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit FXR1P_C PF12235.3 ETS74618.1 - 0.071 13.2 10.5 0.029 14.4 5.2 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal API5 PF05918.6 ETS74618.1 - 1.8 6.9 7.6 2.5 6.4 5.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) His_biosynth PF00977.16 ETS74619.1 - 8.6e-51 172.4 0.5 3.6e-50 170.3 0.4 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 ETS74619.1 - 2.3e-28 98.9 0.0 3.5e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 ETS74619.1 - 1.3e-10 41.1 0.0 5.1e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 ETS74619.1 - 2e-07 30.7 0.0 4.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 ETS74619.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Peptidase C26 Dus PF01207.12 ETS74619.1 - 0.1 11.4 0.1 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) ODC_AZ PF02100.12 ETS74620.1 - 6.6e-28 96.3 0.0 8.4e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 ETS74621.1 - 9.7e-20 70.4 0.1 1.4e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 ETS74621.1 - 0.0007 19.4 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 C-terminal domain of RIG-I Tyr_Deacylase PF02580.11 ETS74622.1 - 3.4e-47 160.0 0.3 4.3e-47 159.7 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 ETS74623.1 - 6.9e-96 320.0 28.6 6.9e-96 320.0 19.8 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 ETS74623.1 - 9.6e-42 142.0 13.5 1.4e-41 141.5 8.3 2.1 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 ETS74623.1 - 0.0065 15.9 3.2 0.015 14.8 2.2 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Endonuc-BglII PF09195.6 ETS74623.1 - 0.12 11.8 5.1 0.073 12.5 1.8 1.9 2 0 0 2 2 2 0 Restriction endonuclease BglII Sec5 PF15469.1 ETS74623.1 - 0.8 9.4 9.7 0.32 10.6 0.8 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Poty_PP PF08440.5 ETS74623.1 - 1.2 8.1 6.7 0.12 11.4 0.8 1.9 2 0 0 2 2 2 0 Potyviridae polyprotein NIT PF08376.5 ETS74623.1 - 1.5 8.2 14.3 0.26 10.7 0.4 3.3 3 1 1 4 4 4 0 Nitrate and nitrite sensing Snapin_Pallidin PF14712.1 ETS74623.1 - 2.4 8.5 10.3 12 6.2 2.0 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Arrestin_N PF00339.24 ETS74624.1 - 3.2e-13 49.7 0.0 2.7e-08 33.7 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 ETS74624.1 - 0.21 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Formyl_trans_N PF00551.14 ETS74625.1 - 4.1e-26 91.6 0.0 6.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase HABP4_PAI-RBP1 PF04774.10 ETS74626.1 - 0.022 15.2 7.8 0.064 13.7 5.4 1.7 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Dehydrin PF00257.14 ETS74626.1 - 0.069 13.4 3.3 0.1 12.9 2.3 1.2 1 0 0 1 1 1 0 Dehydrin CIAPIN1 PF05093.8 ETS74627.1 - 4.8e-35 119.6 3.7 7.6e-35 119.0 2.6 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-MIZ PF02891.15 ETS74628.1 - 5.6e-07 28.9 7.7 2.5e-05 23.6 5.3 2.5 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger SAM_2 PF07647.12 ETS74629.1 - 9.6e-14 50.9 0.0 1.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 ETS74629.1 - 2.4e-13 49.4 0.0 4.7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS74629.1 - 5.5e-11 41.6 0.0 1.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 ETS74629.1 - 1.5e-09 37.9 0.0 3.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETS74629.1 - 6.6e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 ETS74629.1 - 4e-05 23.0 0.0 9.1e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 ETS74629.1 - 0.039 14.1 0.1 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 ETS74629.1 - 0.056 13.5 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_PNT PF02198.11 ETS74629.1 - 0.099 12.4 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain YrbL-PhoP_reg PF10707.4 ETS74630.1 - 0.028 13.7 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_S10 PF00450.17 ETS74631.1 - 5e-112 375.0 0.1 6.7e-112 374.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS74631.1 - 0.0024 17.8 0.0 0.029 14.2 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 ETS74632.1 - 2.8e-08 33.2 11.4 2.7e-06 26.6 7.9 3.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS74632.1 - 0.0024 17.8 1.6 0.0088 16.0 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS74632.1 - 0.05 12.5 3.7 2.4 7.0 0.1 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.5 ETS74632.1 - 0.06 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase DUF3518 PF12031.3 ETS74632.1 - 0.06 12.1 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) NAD_binding_9 PF13454.1 ETS74632.1 - 0.095 12.4 3.7 0.7 9.6 0.2 3.3 2 2 1 3 3 3 0 FAD-NAD(P)-binding PGAP1 PF07819.8 ETS74633.1 - 1.4e-08 34.5 0.1 2.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 ETS74633.1 - 4.6e-07 29.9 0.5 6.2e-07 29.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETS74633.1 - 2.5e-05 23.6 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 ETS74633.1 - 0.00016 21.4 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 ETS74633.1 - 0.00054 19.0 0.0 0.00083 18.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 ETS74633.1 - 0.0073 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 ETS74633.1 - 0.0083 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 ETS74633.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase GspL_C PF12693.2 ETS74633.1 - 0.044 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Lipase_2 PF01674.13 ETS74633.1 - 0.045 13.0 0.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 2) RTA1 PF04479.8 ETS74634.1 - 6.6e-21 74.8 6.9 1e-20 74.2 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein RicinB_lectin_2 PF14200.1 ETS74635.1 - 7.6e-22 77.6 4.4 3.3e-16 59.5 1.8 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETS74635.1 - 2e-08 34.2 0.4 3.9e-08 33.3 0.2 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain TBPIP PF07106.8 ETS74636.1 - 0.0036 16.8 1.0 0.25 10.8 0.1 2.2 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 ETS74636.1 - 0.05 12.9 3.6 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 PspA/IM30 family FlxA PF14282.1 ETS74636.1 - 0.06 13.2 5.1 0.11 12.5 0.7 2.3 2 0 0 2 2 2 0 FlxA-like protein End3 PF12761.2 ETS74636.1 - 0.072 12.7 5.1 0.11 12.1 3.5 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 WXG100 PF06013.7 ETS74636.1 - 0.086 12.8 3.9 0.13 12.3 0.4 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Med9 PF07544.8 ETS74636.1 - 0.096 12.4 0.8 0.54 10.0 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 ETS74636.1 - 0.21 11.6 2.9 1.1 9.3 1.5 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_MT_bd PF06657.8 ETS74636.1 - 0.3 11.0 3.6 0.19 11.6 0.5 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.6 ETS74636.1 - 0.53 9.7 7.9 0.1 12.0 2.3 2.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 bZIP_Maf PF03131.12 ETS74636.1 - 0.54 10.5 3.1 3.1 8.1 0.2 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Swi5 PF07061.6 ETS74636.1 - 0.84 9.4 3.8 14 5.5 0.1 2.5 2 0 0 2 2 2 0 Swi5 Cortex-I_coil PF09304.5 ETS74636.1 - 6.6 6.8 9.3 9.4 6.3 2.4 2.6 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF2935 PF11155.3 ETS74637.1 - 0.00088 19.3 2.5 0.0012 18.9 1.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) ALIX_LYPXL_bnd PF13949.1 ETS74637.1 - 0.00089 18.3 7.1 0.00094 18.2 4.9 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV PilJ PF13675.1 ETS74637.1 - 0.00092 19.5 0.2 0.0013 19.0 0.1 1.2 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term KaiC PF06745.8 ETS74637.1 - 0.0023 17.0 0.6 0.0026 16.9 0.4 1.1 1 0 0 1 1 1 1 KaiC STAT_alpha PF01017.15 ETS74637.1 - 0.0088 15.7 3.3 0.011 15.5 2.3 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain MscS_porin PF12795.2 ETS74637.1 - 0.0097 15.2 4.5 0.015 14.6 3.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF2959 PF11172.3 ETS74637.1 - 0.011 15.5 3.6 0.014 15.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Tropomyosin_1 PF12718.2 ETS74637.1 - 0.012 15.5 10.3 0.014 15.1 7.2 1.3 1 0 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 ETS74637.1 - 0.014 15.4 9.1 0.025 14.6 6.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 ETS74637.1 - 0.017 14.9 3.5 1.8 8.4 0.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ALMT PF11744.3 ETS74637.1 - 0.019 13.6 2.9 0.017 13.7 2.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Rotamase PF00639.16 ETS74637.1 - 0.02 15.6 1.0 0.035 14.8 0.6 1.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain AAA_13 PF13166.1 ETS74637.1 - 0.022 13.2 9.2 0.029 12.8 6.4 1.2 1 0 0 1 1 1 0 AAA domain DUF2413 PF10310.4 ETS74637.1 - 0.026 13.3 1.7 0.033 13.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) GAS PF13851.1 ETS74637.1 - 0.026 13.7 8.1 0.043 13.0 4.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 ETS74637.1 - 0.029 13.6 2.7 0.068 12.4 1.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IL13 PF03487.8 ETS74637.1 - 0.029 14.0 0.1 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin-13 Ran-binding PF05508.6 ETS74637.1 - 0.032 13.1 1.8 0.04 12.8 1.2 1.1 1 0 0 1 1 1 0 RanGTP-binding protein WXG100 PF06013.7 ETS74637.1 - 0.034 14.1 1.0 1.1 9.3 0.1 2.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.4 ETS74637.1 - 0.037 13.8 7.1 0.055 13.3 4.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3144 PF11342.3 ETS74637.1 - 0.038 14.0 1.0 0.1 12.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Myosin_tail_1 PF01576.14 ETS74637.1 - 0.049 11.3 11.3 0.05 11.3 7.9 1.0 1 0 0 1 1 1 0 Myosin tail GrpE PF01025.14 ETS74637.1 - 0.053 13.0 6.0 0.065 12.7 4.1 1.3 1 0 0 1 1 1 0 GrpE TMF_TATA_bd PF12325.3 ETS74637.1 - 0.058 13.1 5.5 0.1 12.3 3.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 ETS74637.1 - 0.063 11.6 5.3 0.073 11.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peripla_BP_2 PF01497.13 ETS74637.1 - 0.065 12.3 0.4 0.087 11.9 0.2 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF4358 PF14270.1 ETS74637.1 - 0.073 12.9 0.7 0.14 12.0 0.2 1.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4358) AAA-ATPase_like PF09820.4 ETS74637.1 - 0.076 12.1 1.3 0.079 12.1 0.9 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase MCC-bdg_PDZ PF10506.4 ETS74637.1 - 0.078 12.8 1.8 0.13 12.1 0.4 1.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3467 PF11950.3 ETS74637.1 - 0.078 12.9 0.2 0.28 11.2 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) ING PF12998.2 ETS74637.1 - 0.081 13.2 2.6 0.32 11.2 1.8 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Baculo_PEP_C PF04513.7 ETS74637.1 - 0.084 12.6 5.2 0.11 12.2 3.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.1 ETS74637.1 - 0.091 12.7 6.6 0.43 10.6 1.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein V-SNARE PF05008.10 ETS74637.1 - 0.092 12.9 5.4 0.3 11.2 3.0 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMPIT PF07851.8 ETS74637.1 - 0.092 11.8 2.8 0.11 11.5 1.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein LOH1CR12 PF10158.4 ETS74637.1 - 0.097 12.4 3.0 0.18 11.5 2.1 1.4 1 1 0 1 1 1 0 Tumour suppressor protein Sec34 PF04136.10 ETS74637.1 - 0.11 12.2 6.4 0.55 9.9 3.9 1.8 1 1 1 2 2 2 0 Sec34-like family GLE1 PF07817.8 ETS74637.1 - 0.11 11.3 0.8 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF4320 PF14208.1 ETS74637.1 - 0.12 12.3 0.8 0.41 10.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) Mod_r PF07200.8 ETS74637.1 - 0.15 12.0 6.4 0.22 11.4 4.4 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SYCE1 PF15233.1 ETS74637.1 - 0.16 11.8 3.7 0.22 11.4 2.2 1.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF1664 PF07889.7 ETS74637.1 - 0.16 11.7 2.1 0.68 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.1 ETS74637.1 - 0.17 11.9 4.7 1.4 9.0 2.8 2.1 1 1 0 1 1 1 0 Sperm tail P35 PF02331.10 ETS74637.1 - 0.19 10.8 5.3 0.24 10.4 3.7 1.1 1 0 0 1 1 1 0 Apoptosis preventing protein DUF2205 PF10224.4 ETS74637.1 - 0.21 11.1 8.0 0.13 11.8 3.6 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Z1 PF10593.4 ETS74637.1 - 0.21 10.7 1.6 0.23 10.6 1.1 1.0 1 0 0 1 1 1 0 Z1 domain DUF3585 PF12130.3 ETS74637.1 - 0.25 11.1 4.7 3.3 7.5 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3585) DUF812 PF05667.6 ETS74637.1 - 0.29 9.6 6.5 0.29 9.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Drf_FH3 PF06367.11 ETS74637.1 - 0.3 10.4 5.4 0.34 10.2 3.7 1.1 1 0 0 1 1 1 0 Diaphanous FH3 Domain DUF2408 PF10303.4 ETS74637.1 - 0.37 10.8 5.5 0.55 10.3 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Uds1 PF15456.1 ETS74637.1 - 0.38 10.7 3.7 0.7 9.8 0.5 2.3 1 1 2 3 3 3 0 Up-regulated During Septation Nbl1_Borealin_N PF10444.4 ETS74637.1 - 0.47 9.8 3.9 1.1 8.6 0.8 2.6 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal DUF883 PF05957.8 ETS74637.1 - 0.47 10.8 3.7 4.7 7.6 0.6 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Rho_Binding PF08912.6 ETS74637.1 - 0.48 10.7 11.9 0.21 11.9 4.5 2.3 1 1 1 2 2 2 0 Rho Binding IncA PF04156.9 ETS74637.1 - 0.49 9.9 5.7 1.7 8.1 3.8 1.7 1 1 1 2 2 2 0 IncA protein CDC37_N PF03234.9 ETS74637.1 - 0.64 10.3 6.7 0.67 10.2 4.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Laminin_II PF06009.7 ETS74637.1 - 0.7 9.6 6.5 3.1 7.5 3.7 1.8 1 1 0 1 1 1 0 Laminin Domain II Syntaxin PF00804.20 ETS74637.1 - 0.71 10.0 8.1 2.2 8.4 3.2 2.1 1 1 1 2 2 2 0 Syntaxin APG6 PF04111.7 ETS74637.1 - 0.77 8.7 8.1 0.83 8.6 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 ETS74637.1 - 0.79 8.3 9.1 0.89 8.1 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 ETS74637.1 - 0.79 9.6 5.9 1.3 8.9 0.5 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.6 ETS74637.1 - 0.88 9.5 7.3 4.7 7.2 4.9 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.5 ETS74637.1 - 1.1 9.3 4.6 2.4 8.2 3.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PilO PF04350.8 ETS74637.1 - 1.2 9.0 4.8 2 8.2 1.6 2.0 1 1 1 2 2 2 0 Pilus assembly protein, PilO DUF745 PF05335.8 ETS74637.1 - 1.2 8.5 5.2 6.7 6.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Cluap1 PF10234.4 ETS74637.1 - 1.3 8.1 7.1 1.4 8.0 5.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 HSCB_C PF07743.8 ETS74637.1 - 1.5 9.3 5.9 1.3 9.5 1.4 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain bZIP_1 PF00170.16 ETS74637.1 - 1.6 8.7 14.1 5.8 6.9 3.9 3.8 1 1 2 3 3 3 0 bZIP transcription factor DASH_Dad3 PF08656.5 ETS74637.1 - 2 8.1 4.7 1.3e+02 2.3 3.2 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 Sec2p PF06428.6 ETS74637.1 - 2.3 8.1 8.1 33 4.3 2.0 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.6 ETS74637.1 - 2.7 7.7 8.7 24 4.6 6.1 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TSC22 PF01166.13 ETS74637.1 - 3 7.8 7.2 1.8 8.5 0.6 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.13 ETS74637.1 - 4 7.2 11.3 4.8 6.9 0.7 3.2 2 2 1 3 3 3 0 Homeobox associated leucine zipper Ly49 PF08391.5 ETS74637.1 - 4.3 7.5 5.5 5.8 7.0 3.7 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region MobC PF05713.6 ETS74637.1 - 7.1 6.6 8.7 35 4.4 6.1 2.3 1 1 0 1 1 1 0 Bacterial mobilisation protein (MobC) DHquinase_I PF01487.10 ETS74638.1 - 5.8e-56 189.6 0.0 8.7e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 ETS74639.1 - 1.5e-27 96.1 0.0 2.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74639.1 - 3e-05 23.8 15.7 5.3e-05 23.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 ETS74639.1 - 2.4 6.8 5.1 4.9 5.8 3.5 1.4 1 0 0 1 1 1 0 Clusterin NAD_binding_6 PF08030.7 ETS74640.1 - 3.6e-20 72.4 0.0 5.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 ETS74640.1 - 1.2e-13 51.2 10.7 1.2e-13 51.2 7.4 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS74640.1 - 8.1e-12 44.9 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 ETS74640.1 - 1.6e-05 25.4 0.0 0.0022 18.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DoxX_3 PF13781.1 ETS74640.1 - 1.9 8.9 8.9 1.3 9.3 2.0 2.6 1 1 1 2 2 2 0 DoxX-like family DHO_dh PF01180.16 ETS74641.1 - 1.4e-23 83.3 0.0 1.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 ETS74641.1 - 0.55 9.3 5.6 0.7 8.9 3.5 1.4 2 0 0 2 2 2 0 Nitronate monooxygenase 3HCDH_N PF02737.13 ETS74642.1 - 3.9e-35 121.1 0.0 5.4e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS74642.1 - 1.4e-11 44.5 0.0 3.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETS74642.1 - 8.4e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS74642.1 - 2e-06 27.5 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldl_recept_b PF00058.12 ETS74642.1 - 0.00012 22.2 0.2 8.3 6.8 0.0 5.2 5 1 0 5 5 5 1 Low-density lipoprotein receptor repeat class B Saccharop_dh PF03435.13 ETS74642.1 - 0.00044 19.3 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 ETS74642.1 - 0.001 18.2 0.1 0.0051 15.9 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arylesterase PF01731.15 ETS74642.1 - 0.0055 16.6 0.0 13 5.8 0.0 3.6 3 0 0 3 3 3 1 Arylesterase Sortase PF04203.8 ETS74642.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Sortase family F420_oxidored PF03807.12 ETS74642.1 - 0.027 14.8 0.0 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 ETS74642.1 - 0.045 13.1 0.0 0.15 11.5 0.0 1.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA RRM_1 PF00076.17 ETS74643.1 - 5.1e-17 61.2 0.0 7.8e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS74643.1 - 4.5e-16 58.5 0.0 8.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS74643.1 - 3.3e-05 23.6 0.0 5.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 ETS74643.1 - 0.011 15.3 1.0 0.013 15.0 0.7 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 ETS74643.1 - 0.092 13.1 0.7 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 ETS74643.1 - 0.22 11.0 4.0 0.35 10.3 2.7 1.2 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 ETS74643.1 - 0.29 8.9 0.7 0.33 8.7 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FadA PF09403.5 ETS74643.1 - 0.52 10.3 4.2 0.76 9.8 2.9 1.2 1 0 0 1 1 1 0 Adhesion protein FadA DUF4337 PF14235.1 ETS74643.1 - 2.6 7.8 4.9 3.4 7.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HECT PF00632.20 ETS74644.1 - 1.5e-91 306.8 0.0 2.1e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 ETS74644.1 - 1.9e-33 113.9 21.9 1.8e-11 43.7 4.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 ETS74644.1 - 5.8e-17 61.3 0.1 1.6e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain CopC PF04234.7 ETS74645.1 - 0.086 13.4 0.5 0.28 11.8 0.0 2.1 2 0 0 2 2 2 0 CopC domain Lsm_interact PF05391.6 ETS74645.1 - 0.12 11.8 0.7 0.4 10.1 0.5 2.0 1 0 0 1 1 1 0 Lsm interaction motif Alba PF01918.16 ETS74646.1 - 0.0011 18.5 0.5 0.0025 17.3 0.3 1.6 1 0 0 1 1 1 1 Alba Pilt PF15453.1 ETS74646.1 - 0.0081 15.8 1.8 0.01 15.5 1.0 1.4 1 1 0 1 1 1 1 Protein incorporated later into Tight Junctions tRNA-synt_His PF13393.1 ETS74646.1 - 0.023 13.7 1.1 0.037 13.0 0.8 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF202 PF02656.10 ETS74647.1 - 2.3e-13 50.1 3.6 2.3e-13 50.1 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 ETS74647.1 - 0.024 14.2 4.9 0.031 13.8 3.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MARVEL PF01284.18 ETS74647.1 - 0.089 12.6 3.5 0.15 11.8 2.5 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF2615 PF11027.3 ETS74647.1 - 0.78 9.6 3.0 2.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) 7TMR-DISM_7TM PF07695.6 ETS74647.1 - 0.82 9.3 8.5 2.6 7.6 5.9 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2207 PF09972.4 ETS74647.1 - 3.2 6.2 5.1 0.67 8.4 1.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Tctex-1 PF03645.8 ETS74648.1 - 1.8e-34 117.6 0.0 2.1e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.2 ETS74650.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like CTP_transf_2 PF01467.21 ETS74651.1 - 6.7e-22 78.2 0.0 1.2e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Fungal_trans PF04082.13 ETS74652.1 - 1.4e-09 37.2 0.6 3.6e-09 35.8 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS74652.1 - 2.4e-06 27.5 8.6 0.0021 18.2 2.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS74652.1 - 5.3e-06 26.3 11.0 0.0006 19.9 2.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2376 PF09550.5 ETS74652.1 - 0.035 14.2 1.9 0.13 12.4 1.3 2.0 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) DUF3948 PF13134.1 ETS74652.1 - 0.46 10.0 3.7 1.2 8.6 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Ion_trans PF00520.26 ETS74654.1 - 1.1e-07 31.3 1.2 1.7e-07 30.7 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein bZIP_1 PF00170.16 ETS74654.1 - 0.00026 20.8 1.1 0.00026 20.8 0.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 ETS74654.1 - 0.0033 17.2 0.2 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein bZIP_2 PF07716.10 ETS74654.1 - 0.0063 16.3 1.5 0.0063 16.3 1.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper HSBP1 PF06825.7 ETS74654.1 - 0.092 12.3 0.4 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF2201_N PF13203.1 ETS74655.1 - 0.15 11.1 1.1 0.19 10.8 0.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MGC-24 PF05283.6 ETS74655.1 - 0.45 10.2 25.1 0.56 9.9 17.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DNA_pol_viral_N PF00242.12 ETS74655.1 - 0.63 9.0 4.7 0.65 8.9 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CFEM PF05730.6 ETS74655.1 - 1.7 8.5 12.0 6.7 6.6 8.0 2.3 1 1 0 1 1 1 0 CFEM domain Macoilin PF09726.4 ETS74655.1 - 8.7 4.4 10.7 11 4.2 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Oxidored_q6 PF01058.17 ETS74656.1 - 2e-22 79.1 0.0 2.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit RbcS PF12338.3 ETS74656.1 - 0.76 9.5 4.5 0.62 9.8 1.6 2.0 2 1 1 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit MFS_1 PF07690.11 ETS74658.1 - 4e-33 114.5 56.1 9.7e-33 113.3 38.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74658.1 - 1.6e-11 43.5 26.6 3.6e-11 42.3 17.7 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter GST_N_3 PF13417.1 ETS74660.1 - 1.2e-13 51.0 0.0 6.4e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS74660.1 - 1.5e-12 47.4 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS74660.1 - 2.7e-12 46.4 0.0 5.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS74660.1 - 1e-09 38.2 0.1 2e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS74660.1 - 1.4e-06 28.1 0.1 2.4e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS74660.1 - 0.0054 17.1 0.1 0.0076 16.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 ETS74661.1 - 8.6e-28 97.1 0.6 1e-27 96.9 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74661.1 - 3.8e-14 53.0 6.2 4.1e-14 53.0 3.5 1.7 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS74661.1 - 1.2e-05 24.8 1.3 1.8e-05 24.2 0.4 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 ETS74661.1 - 0.00035 19.6 1.0 0.00035 19.6 0.7 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS74661.1 - 0.0013 19.0 1.6 0.0021 18.3 0.5 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS74661.1 - 0.015 15.2 3.0 0.029 14.2 2.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ELFV_dehydrog PF00208.16 ETS74661.1 - 0.018 14.6 0.7 0.029 13.9 0.1 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_reductoisom PF02670.11 ETS74661.1 - 0.05 14.1 3.5 5.2 7.6 0.0 2.7 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 ETS74661.1 - 0.064 13.1 1.9 0.21 11.5 1.3 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 ETS74661.1 - 0.11 12.9 2.3 0.26 11.7 1.6 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 ETS74661.1 - 0.11 11.3 4.9 0.05 12.4 0.8 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 ETS74661.1 - 0.12 11.4 2.8 0.18 10.8 0.6 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 ETS74661.1 - 0.27 10.8 4.5 0.22 11.0 1.7 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_2_N PF02837.13 ETS74662.1 - 2.1e-27 95.7 2.1 7.2e-27 93.9 1.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS74662.1 - 1.4e-09 38.3 0.0 6.3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 ETS74662.1 - 3e-09 36.2 0.0 5.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.1 ETS74662.1 - 0.038 14.2 2.2 0.2 11.9 0.5 2.4 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain zf-C3HC4_2 PF13923.1 ETS74663.1 - 5.1e-08 32.7 7.5 9.5e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS74663.1 - 7e-08 32.0 5.9 1.4e-07 31.0 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS74663.1 - 2e-07 30.7 5.7 3.6e-07 29.8 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS74663.1 - 2.6e-07 30.1 6.1 4.6e-07 29.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS74663.1 - 1e-06 28.3 5.2 1.8e-06 27.5 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS74663.1 - 5e-05 23.0 2.4 5e-05 23.0 1.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS74663.1 - 5.9e-05 22.7 5.0 0.0064 16.1 0.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-Nse PF11789.3 ETS74663.1 - 0.061 12.8 5.3 0.15 11.5 3.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY-C PF15616.1 ETS74663.1 - 0.12 12.3 3.3 0.79 9.6 2.3 2.1 1 1 0 1 1 1 0 TerY-C metal binding domain DUF3285 PF11688.3 ETS74663.1 - 0.16 11.6 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) zf-rbx1 PF12678.2 ETS74663.1 - 0.5 10.5 4.5 2.2 8.4 3.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 ETS74663.1 - 1.2 9.1 6.0 14 5.6 4.3 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.15 ETS74663.1 - 2.3 7.7 7.2 8.4 6.0 5.0 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Lipase_GDSL_2 PF13472.1 ETS74664.1 - 4.7e-13 49.6 1.6 5.7e-13 49.3 1.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS74664.1 - 1.2e-09 38.3 0.7 1.7e-09 37.8 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_8 PF08022.7 ETS74665.1 - 5.6e-20 71.1 0.0 9.8e-19 67.1 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 ETS74665.1 - 1.8e-12 47.4 1.7 4.3e-12 46.2 1.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS74665.1 - 1.5e-11 44.4 0.0 4.6e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.27 ETS74665.1 - 0.0053 15.9 0.1 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETS74665.1 - 0.006 16.6 0.8 0.023 14.8 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair FAD_binding_6 PF00970.19 ETS74665.1 - 0.064 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_6 PF13405.1 ETS74665.1 - 0.073 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 ETS74665.1 - 0.098 12.0 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 EF hand GST_N_3 PF13417.1 ETS74666.1 - 2.9e-17 62.6 0.0 9.6e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS74666.1 - 1.1e-13 50.9 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS74666.1 - 4.9e-10 39.4 0.0 9.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS74666.1 - 2.8e-05 23.9 0.1 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 ETS74666.1 - 0.0051 16.7 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin RPE65 PF03055.10 ETS74667.1 - 2.5e-104 349.5 0.0 2.8e-104 349.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Hormone_3 PF00159.13 ETS74668.1 - 0.0013 18.7 3.7 0.013 15.4 0.4 2.6 2 0 0 2 2 2 2 Pancreatic hormone peptide Patatin PF01734.17 ETS74669.1 - 4.1e-22 79.1 0.0 7.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-B_box PF00643.19 ETS74669.1 - 0.001 18.9 10.1 0.0044 16.8 2.8 2.6 2 0 0 2 2 2 1 B-box zinc finger AAA_16 PF13191.1 ETS74669.1 - 0.0014 18.6 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 ETS74669.1 - 0.0022 18.2 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 ETS74669.1 - 0.0026 17.7 0.0 0.0067 16.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 ETS74669.1 - 0.0047 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 ETS74669.1 - 0.0081 15.9 0.6 0.062 13.1 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 Miro PF08477.8 ETS74669.1 - 0.011 16.2 0.0 0.36 11.3 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein AAA_22 PF13401.1 ETS74669.1 - 0.031 14.4 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS74669.1 - 0.044 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 ETS74669.1 - 0.076 12.7 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETS74669.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS74669.1 - 0.19 12.0 0.1 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.1 ETS74669.1 - 1.6 8.8 21.9 0.41 10.7 5.0 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS74669.1 - 3 7.5 18.4 0.83 9.3 3.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFO_IDH_MocA PF01408.17 ETS74670.1 - 1.6e-21 77.0 0.0 2.9e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS74670.1 - 4.7e-10 39.2 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 ETS74670.1 - 0.0013 19.1 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 ETS74670.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AAA_33 PF13671.1 ETS74670.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain MIT PF04212.13 ETS74671.1 - 3.7e-12 45.9 0.4 1e-11 44.5 0.2 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CheY-binding PF09078.6 ETS74671.1 - 0.19 11.7 0.5 0.43 10.6 0.3 1.5 1 0 0 1 1 1 0 CheY binding Lipase_GDSL PF00657.17 ETS74672.1 - 4.3e-07 29.9 0.1 8.1e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.13 ETS74673.1 - 1e-27 96.6 0.1 1.4e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.16 ETS74674.1 - 6.5e-45 153.0 0.0 8.4e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain WG_beta_rep PF14903.1 ETS74674.1 - 0.17 12.1 1.1 13 6.2 0.0 3.0 3 0 0 3 3 3 0 WG containing repeat ADH_zinc_N PF00107.21 ETS74675.1 - 2.5e-25 88.5 0.2 3.8e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS74675.1 - 7.3e-16 59.2 0.2 2.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS74675.1 - 1.2e-06 28.2 0.1 1.1e-05 25.1 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.20 ETS74675.1 - 0.02 14.1 0.3 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.19 ETS74676.1 - 8.2e-35 120.4 2.4 7.8e-30 104.0 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS74676.1 - 1.3e-08 34.9 0.0 0.0011 18.9 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS74676.1 - 3.9e-07 29.3 1.1 3.9e-07 29.3 0.8 2.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS74676.1 - 7e-05 21.4 2.6 0.21 10.0 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.2 ETS74676.1 - 0.00073 18.7 0.3 0.0029 16.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS74676.1 - 0.0008 18.3 1.7 0.062 12.1 0.3 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS74676.1 - 0.054 13.5 0.4 0.19 11.7 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS74676.1 - 0.13 11.1 0.1 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Amidohydro_2 PF04909.9 ETS74677.1 - 2.5e-19 69.9 0.5 3e-19 69.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF221 PF02714.10 ETS74679.1 - 5.5e-96 321.2 20.0 3e-95 318.7 11.3 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS74679.1 - 1.7e-43 147.9 3.3 5.1e-43 146.3 2.3 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 ETS74679.1 - 1.2e-24 85.9 0.6 2.4e-24 85.0 0.4 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 ETS74679.1 - 1.5e-07 31.7 0.5 1.5e-07 31.7 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) HEAT_2 PF13646.1 ETS74680.1 - 9.4e-28 96.3 27.4 3.9e-08 33.4 1.1 6.8 4 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 ETS74680.1 - 6.2e-15 53.8 12.7 0.15 12.2 0.0 9.2 10 0 0 10 10 9 5 HEAT repeat NACHT PF05729.7 ETS74680.1 - 1.3e-14 54.2 0.0 8.9e-14 51.4 0.0 2.6 2 0 0 2 2 1 1 NACHT domain NB-ARC PF00931.17 ETS74680.1 - 4.5e-06 25.7 0.0 1.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.8 ETS74680.1 - 3.2e-05 23.6 0.0 7.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_17 PF13207.1 ETS74680.1 - 4.6e-05 24.2 0.0 0.0015 19.3 0.0 3.4 4 0 0 4 4 2 1 AAA domain Vac14_Fab1_bd PF12755.2 ETS74680.1 - 8.5e-05 22.8 4.0 0.59 10.5 0.1 5.6 5 2 1 6 6 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETS74680.1 - 8.8e-05 22.8 26.0 3.7 8.1 0.0 8.2 7 3 3 11 11 8 2 HEAT-like repeat Cohesin_HEAT PF12765.2 ETS74680.1 - 0.00014 21.7 6.6 0.026 14.4 0.0 4.9 5 0 0 5 5 4 1 HEAT repeat associated with sister chromatid cohesion AAA PF00004.24 ETS74680.1 - 0.00019 21.6 0.0 0.0006 20.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS74680.1 - 0.00047 20.2 0.0 0.0049 17.0 0.0 2.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 ETS74680.1 - 0.00096 19.4 0.0 0.0066 16.7 0.0 2.6 2 0 0 2 2 1 1 AAA domain DUF676 PF05057.9 ETS74680.1 - 0.0023 17.2 0.0 0.005 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 ETS74680.1 - 0.0033 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase AAA_14 PF13173.1 ETS74680.1 - 0.0044 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS74680.1 - 0.0059 16.3 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain NTPase_1 PF03266.10 ETS74680.1 - 0.0064 16.2 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 ETS74680.1 - 0.0065 16.4 3.7 0.061 13.3 0.0 4.0 4 1 0 5 5 4 1 AAA ATPase domain DNA_alkylation PF08713.6 ETS74680.1 - 0.0076 15.7 2.1 0.035 13.6 0.8 2.7 1 1 1 2 2 2 1 DNA alkylation repair enzyme RNA_helicase PF00910.17 ETS74680.1 - 0.0087 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Abhydrolase_6 PF12697.2 ETS74680.1 - 0.012 15.4 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family T2SE PF00437.15 ETS74680.1 - 0.024 13.5 0.0 0.24 10.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IclR PF01614.13 ETS74680.1 - 0.026 14.1 1.5 4.8 6.8 0.0 3.4 3 1 1 4 4 3 0 Bacterial transcriptional regulator Cnd1 PF12717.2 ETS74680.1 - 0.029 14.2 10.6 0.52 10.1 0.1 5.2 4 1 2 6 6 5 0 non-SMC mitotic condensation complex subunit 1 AAA_24 PF13479.1 ETS74680.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 ETS74680.1 - 0.24 11.1 0.0 0.77 9.5 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family Arm PF00514.18 ETS74680.1 - 0.35 10.7 10.1 4.5 7.2 0.0 6.1 7 1 1 8 8 7 0 Armadillo/beta-catenin-like repeat BioW PF03744.8 ETS74680.1 - 0.67 9.3 3.9 36 3.6 0.0 3.7 4 1 0 4 4 3 0 6-carboxyhexanoate--CoA ligase Nsp1_C PF05064.8 ETS74681.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Chitin_bind_1 PF00187.14 ETS74682.1 - 8.4e-28 96.0 296.4 0.00098 19.0 15.3 11.2 10 1 0 10 10 10 10 Chitin recognition protein Glyco_hydro_18 PF00704.23 ETS74683.1 - 1.4e-63 215.4 1.2 2.1e-63 214.8 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS74683.1 - 2e-06 27.6 8.8 2e-06 27.6 6.1 3.8 4 0 0 4 4 4 2 Chitin recognition protein adh_short_C2 PF13561.1 ETS74684.1 - 7.3e-36 124.1 0.2 8.6e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS74684.1 - 1.5e-25 90.0 1.4 2.3e-25 89.4 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74684.1 - 4e-17 62.4 0.4 5.2e-17 62.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS74684.1 - 0.00037 20.0 0.1 0.00053 19.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS74684.1 - 0.03 13.0 0.1 0.037 12.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS74684.1 - 0.074 13.0 2.1 0.23 11.4 1.4 1.8 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_3 PF00933.16 ETS74686.1 - 1.3e-27 96.5 0.0 1.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS74686.1 - 8.5e-27 94.1 0.0 9.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.19 ETS74687.1 - 1.2e-75 254.8 20.6 1.4e-75 254.6 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74687.1 - 1.8e-22 79.5 66.8 3.3e-19 68.8 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GP41 PF00517.12 ETS74687.1 - 1.7 8.2 9.9 0.51 9.8 0.4 3.0 3 0 0 3 3 3 0 Retroviral envelope protein Tyrosinase PF00264.15 ETS74688.1 - 2.3e-42 145.6 0.8 4.5e-42 144.7 0.5 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase DEC-1_N PF04625.8 ETS74688.1 - 0.0058 15.3 8.0 0.0087 14.7 5.5 1.3 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region GMC_oxred_N PF00732.14 ETS74689.1 - 7.6e-51 173.0 0.5 1.5e-49 168.7 0.3 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS74689.1 - 2.9e-34 118.4 0.0 6.6e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS74689.1 - 1.3e-05 24.2 1.2 0.00052 18.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS74689.1 - 1.7e-05 24.7 1.5 2.6e-05 24.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS74689.1 - 4.3e-05 22.6 0.1 7.4e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS74689.1 - 0.00031 20.7 0.1 0.0032 17.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS74689.1 - 0.00035 19.5 1.3 0.0012 17.8 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS74689.1 - 0.0031 16.0 0.4 0.13 10.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS74689.1 - 0.0032 16.5 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS74689.1 - 0.034 14.5 0.1 0.09 13.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS74689.1 - 0.094 12.7 0.5 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 ETS74689.1 - 0.1 12.3 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.17 ETS74690.1 - 3.1e-73 246.9 0.0 4.1e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4646 PF15496.1 ETS74691.1 - 0.0011 18.9 0.4 0.0033 17.4 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4646) AAT PF03417.11 ETS74692.1 - 0.034 13.6 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 ETS74693.1 - 5.1e-20 71.6 0.0 6.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IU_nuc_hydro PF01156.14 ETS74694.1 - 9.7e-56 189.2 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Sugar_tr PF00083.19 ETS74695.1 - 3.3e-94 316.0 28.7 3.8e-94 315.8 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74695.1 - 2.5e-19 69.1 33.2 4.5e-18 65.0 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nro1 PF12753.2 ETS74696.1 - 0.039 12.9 8.9 0.045 12.7 6.2 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF4172 PF13776.1 ETS74696.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) CN_hydrolase PF00795.17 ETS74699.1 - 1e-45 155.4 0.1 2.9e-23 82.1 0.1 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase adh_short PF00106.20 ETS74700.1 - 6e-21 75.0 0.1 1e-20 74.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS74700.1 - 3.1e-11 43.4 0.0 4.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS74700.1 - 9.3e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 ETS74701.1 - 4.1e-07 29.1 0.9 6.9e-07 28.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74701.1 - 7.7e-05 22.5 9.4 0.00013 21.7 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7TM_GPCR_Str PF10326.4 ETS74701.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str MFS_1 PF07690.11 ETS74702.1 - 8.7e-25 87.1 31.5 8.7e-25 87.1 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SdpI PF13630.1 ETS74702.1 - 3.3 7.4 20.3 4 7.2 1.2 4.6 4 0 0 4 4 4 0 SdpI/YhfL protein family Pyr_redox_3 PF13738.1 ETS74703.1 - 1.6e-17 64.2 0.0 3.5e-17 63.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS74703.1 - 3.1e-07 28.9 0.0 1.2e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS74703.1 - 8.2e-06 25.8 0.0 2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS74703.1 - 0.00017 21.5 0.0 0.00087 19.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS74703.1 - 0.1 11.6 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Sporozoite_P67 PF05642.6 ETS74704.1 - 9.6 3.9 19.5 15 3.3 13.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 ETS74705.1 - 1e-60 199.6 26.4 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS74705.1 - 1.5e-05 23.3 8.1 0.24 9.4 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS74705.1 - 0.0097 14.2 0.1 2.3 6.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain mRNA_stabil PF13929.1 ETS74705.1 - 0.11 11.4 0.1 0.33 9.8 0.0 1.7 2 0 0 2 2 2 0 mRNA stabilisation Bromo_TP PF07524.8 ETS74706.1 - 1.1e-16 60.3 0.1 2.7e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 ETS74706.1 - 1.1e-11 44.6 0.1 3e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term LRR_8 PF13855.1 ETS74707.1 - 2.4e-18 65.6 11.9 7e-08 32.1 1.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 ETS74707.1 - 2.2e-17 62.2 0.7 0.001 18.6 0.0 5.0 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.12 ETS74707.1 - 7.9e-16 57.8 0.0 3.7e-14 52.4 0.0 2.2 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 ETS74707.1 - 2.4e-14 53.1 0.0 5.5e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_1 PF00560.28 ETS74707.1 - 1.3e-11 42.7 4.1 0.38 10.9 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich Repeat Kdo PF06293.9 ETS74707.1 - 2.5e-06 26.6 0.0 4.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETS74707.1 - 0.00014 20.8 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_7 PF13504.1 ETS74707.1 - 0.0031 17.4 7.8 3.9 8.0 0.0 5.5 6 0 0 6 6 5 1 Leucine rich repeat APH PF01636.18 ETS74707.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 ETS74707.1 - 0.051 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family LRR_6 PF13516.1 ETS74707.1 - 2.5 8.4 7.2 11 6.4 0.0 4.4 5 0 0 5 5 4 0 Leucine Rich repeat 2OG-FeII_Oxy_2 PF13532.1 ETS74708.1 - 1.7e-25 89.9 0.1 3e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 ETS74708.1 - 8.4e-24 84.4 0.0 3.7e-23 82.3 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.1 ETS74708.1 - 7.2e-05 23.2 0.1 0.0002 21.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS74708.1 - 0.0025 17.7 0.0 0.0086 16.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS74708.1 - 0.017 14.9 0.2 0.046 13.6 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEK_C PF08766.6 ETS74708.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 DEK C terminal domain NTP_transferase PF00483.18 ETS74709.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.6 1 1 1 2 2 2 0 Nucleotidyl transferase Ribosomal_L22 PF00237.14 ETS74710.1 - 4.9e-18 64.9 0.3 3.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e DUF2508 PF10704.4 ETS74710.1 - 0.0079 16.3 1.3 0.0079 16.3 0.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2508) GMC_oxred_C PF05199.8 ETS74711.1 - 3e-28 98.9 0.0 5.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS74711.1 - 1.1e-25 90.3 0.0 8.3e-23 80.9 0.0 3.1 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS74711.1 - 0.0011 18.8 1.3 0.0042 16.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS74711.1 - 0.0058 15.5 2.0 0.081 11.8 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS74711.1 - 0.0075 16.2 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS74711.1 - 0.018 15.0 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS74711.1 - 0.046 12.1 0.3 0.075 11.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 ETS74711.1 - 0.052 12.4 1.8 0.13 11.0 0.8 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 ETS74711.1 - 0.39 9.5 1.0 0.58 9.0 0.7 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M28 PF04389.12 ETS74712.1 - 2e-31 109.0 0.1 3.6e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS74712.1 - 1.7e-15 56.5 0.3 3.7e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 PA domain CrtC PF07143.6 ETS74715.1 - 9.9e-17 61.1 3.5 5.2e-16 58.8 2.4 1.8 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) PSII PF00421.14 ETS74716.1 - 0.018 13.6 0.0 0.053 12.1 0.0 1.7 2 0 0 2 2 2 0 Photosystem II protein Hpre_diP_synt_I PF07456.6 ETS74716.1 - 0.44 10.3 5.2 0.1 12.4 0.4 2.3 3 0 0 3 3 3 0 Heptaprenyl diphosphate synthase component I Pro_racemase PF05544.6 ETS74717.1 - 1.8e-122 408.2 0.1 2e-122 408.0 0.1 1.0 1 0 0 1 1 1 1 Proline racemase OCD_Mu_crystall PF02423.10 ETS74718.1 - 1.3e-09 37.2 0.0 1.5e-06 27.2 0.0 2.7 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 ETS74718.1 - 4.8e-06 26.7 0.0 3.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Aa_trans PF01490.13 ETS74719.1 - 1.7e-43 148.6 36.7 2e-43 148.4 25.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 ETS74719.1 - 0.02 13.4 49.6 2.5 6.5 34.1 2.5 1 1 0 1 1 1 0 Amino acid permease Pertus-S5-tox PF09276.5 ETS74719.1 - 0.13 12.2 0.5 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Pertussis toxin S5 subunit Fungal_trans PF04082.13 ETS74720.1 - 6.6e-15 54.6 0.2 1.5e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lyase_1 PF00206.15 ETS74721.1 - 2.8e-89 299.3 0.0 3.8e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 ETS74721.1 - 8.4e-26 89.8 0.0 1.6e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.4 ETS74721.1 - 0.043 13.3 0.5 0.35 10.3 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain ADH_zinc_N PF00107.21 ETS74722.1 - 1.8e-23 82.5 0.0 3.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS74722.1 - 2.7e-09 37.9 0.0 6.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 ETS74722.1 - 0.006 16.6 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Ank_2 PF12796.2 ETS74723.1 - 3.7e-49 165.0 0.0 3.6e-10 40.0 0.0 7.5 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74723.1 - 2.7e-32 108.9 15.1 5.9e-06 25.8 0.0 12.1 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 ETS74723.1 - 4.4e-32 109.8 10.3 1.5e-10 41.3 0.0 9.5 8 2 3 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74723.1 - 7.6e-30 99.9 3.3 0.02 15.1 0.0 11.5 11 0 0 11 11 10 5 Ankyrin repeat Ank_5 PF13857.1 ETS74723.1 - 2.8e-26 90.9 20.1 2.7e-06 27.4 0.4 10.6 8 3 3 11 11 11 6 Ankyrin repeats (many copies) AAA_22 PF13401.1 ETS74723.1 - 8e-07 29.2 0.0 2.7e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS74723.1 - 2e-05 24.2 0.0 6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS74723.1 - 7.7e-05 22.7 0.0 0.00031 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PIF1 PF05970.9 ETS74723.1 - 0.0059 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Kinesin PF00225.18 ETS74723.1 - 0.0074 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_30 PF13604.1 ETS74723.1 - 0.018 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETS74723.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AMP-binding PF00501.23 ETS74724.1 - 1.4e-52 178.4 0.0 1.8e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 ETS74724.1 - 4.8e-29 102.1 0.0 1.1e-28 101.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 ETS74724.1 - 1e-09 38.5 0.2 2.9e-09 37.0 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 ETS74724.1 - 0.00047 20.1 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74724.1 - 0.021 14.5 0.0 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family PE-PPE PF08237.6 ETS74724.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain ADH_N PF08240.7 ETS74725.1 - 5.3e-08 32.6 0.1 1.7e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS74725.1 - 0.0079 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TLD PF07534.11 ETS74726.1 - 1.5e-28 99.5 0.0 1.3e-27 96.5 0.0 2.1 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 ETS74726.1 - 2.4e-12 46.8 0.9 5e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 ETS74727.1 - 3.1e-15 55.6 1.4 7e-15 54.5 1.0 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ELYS PF13934.1 ETS74727.1 - 0.012 15.3 0.5 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly DUF1168 PF06658.7 ETS74727.1 - 0.29 10.6 12.5 0.54 9.7 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) TAF4 PF05236.9 ETS74727.1 - 0.5 9.5 11.3 0.7 9.1 7.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Adeno_VII PF03228.9 ETS74727.1 - 0.57 10.7 5.6 1.6 9.3 3.9 1.7 1 1 0 1 1 1 0 Adenoviral core protein VII Nop25 PF09805.4 ETS74727.1 - 3 7.8 19.2 0.15 12.1 9.6 1.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PALP PF00291.20 ETS74728.1 - 1.2e-72 244.7 0.9 1.6e-72 244.3 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 ETS74728.1 - 1.1e-42 143.5 0.0 4.6e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 ETS74729.1 - 3e-05 23.8 4.3 5.3e-05 23.1 3.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 GCR PF02155.10 ETS74729.1 - 0.22 10.1 1.9 0.24 10.1 1.3 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor Acetyltransf_1 PF00583.19 ETS74730.1 - 1.1e-16 60.6 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS74730.1 - 2.6e-10 40.2 0.1 4.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS74730.1 - 1.4e-06 28.3 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS74730.1 - 6.2e-06 26.3 0.0 1e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS74730.1 - 1.8e-05 24.4 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 ETS74730.1 - 1.8e-05 24.9 0.0 2.8e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS74730.1 - 3.5e-05 23.7 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2156 PF09924.4 ETS74730.1 - 0.00074 18.4 0.0 0.002 17.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Acetyltransf_9 PF13527.1 ETS74730.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS74730.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HAD_2 PF13419.1 ETS74731.1 - 4.5e-25 88.8 0.0 8.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS74731.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans_2 PF13249.1 ETS74731.1 - 0.00035 20.9 0.0 0.88 10.0 0.0 2.3 2 0 0 2 2 2 2 Prenyltransferase-like Arg_repressor_C PF02863.13 ETS74733.1 - 0.032 13.6 0.0 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain HsbA PF12296.3 ETS74734.1 - 0.0019 18.0 2.0 0.0019 18.0 1.4 1.8 1 1 0 1 1 1 1 Hydrophobic surface binding protein A OppC_N PF12911.2 ETS74736.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF3328 PF11807.3 ETS74736.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Kelch_3 PF13415.1 ETS74737.1 - 2.6e-34 116.5 4.9 1.8e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS74737.1 - 3.1e-28 97.2 9.1 8.3e-15 54.3 0.0 6.7 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS74737.1 - 1.1e-20 72.7 0.1 0.00022 21.2 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 ETS74737.1 - 4.3e-14 52.0 0.2 0.44 10.5 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 ETS74737.1 - 1.1e-12 47.3 0.4 0.061 12.8 0.0 6.1 6 2 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 ETS74737.1 - 1.2e-09 37.4 2.2 0.048 13.4 0.1 5.8 5 1 0 5 5 5 3 Kelch motif PQQ_2 PF13360.1 ETS74737.1 - 0.015 14.7 0.1 0.14 11.5 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain Fungal_trans PF04082.13 ETS74738.1 - 2.6e-14 52.7 1.1 9.7e-14 50.8 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Paxillin PF03535.8 ETS74738.1 - 0.17 11.6 4.2 0.15 11.8 1.0 2.2 2 1 0 2 2 2 0 Paxillin family Zn_clus PF00172.13 ETS74738.1 - 0.85 9.5 5.4 0.16 11.9 0.8 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PGAMP PF07644.6 ETS74741.1 - 1 9.1 2.8 1.3 8.7 0.0 2.4 3 0 0 3 3 3 0 Planctomycete PGAMP Glyco_hydro_18 PF00704.23 ETS74742.1 - 2.3e-75 254.2 0.8 2.8e-75 253.9 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS74742.1 - 3.6e-11 42.8 16.5 3.6e-11 42.8 11.5 1.8 2 0 0 2 2 2 1 Chitin recognition protein PLAC8 PF04749.12 ETS74743.1 - 2.6e-18 66.5 1.7 3.4e-18 66.1 1.2 1.1 1 0 0 1 1 1 1 PLAC8 family ZZ PF00569.12 ETS74744.1 - 6.7e-11 41.5 8.3 1.1e-10 40.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 ETS74744.1 - 5.1e-10 37.9 7.1 0.00015 20.7 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 ETS74744.1 - 9.1e-09 35.3 2.0 0.0019 18.3 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 ETS74744.1 - 8.5e-06 25.2 1.4 0.021 14.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS74744.1 - 9.1e-06 25.1 5.9 0.0047 16.6 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 ETS74744.1 - 0.23 11.2 1.8 1.3 8.7 0.0 2.9 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 ETS74744.1 - 3.7 7.0 5.5 5 6.6 0.1 3.1 3 0 0 3 3 3 0 EF hand Hce2 PF14856.1 ETS74746.1 - 7.8e-18 64.1 0.1 1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor p450 PF00067.17 ETS74747.1 - 2.3e-53 181.3 0.0 3.6e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M50B PF13398.1 ETS74748.1 - 1.3e-55 187.8 19.7 1.9e-55 187.3 13.7 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M41 PF01434.13 ETS74748.1 - 0.016 14.6 0.1 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M50 PF02163.17 ETS74748.1 - 0.017 14.1 0.3 0.017 14.1 0.2 2.9 2 2 1 3 3 3 0 Peptidase family M50 YlaC PF10777.4 ETS74748.1 - 2.9 7.4 5.9 0.21 11.1 0.2 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC FAD_binding_3 PF01494.14 ETS74749.1 - 1.5e-46 159.0 0.0 2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS74749.1 - 1.3e-07 30.8 0.0 0.0026 16.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS74749.1 - 9.9e-06 24.7 0.1 0.013 14.4 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS74749.1 - 2.1e-05 24.4 0.0 5.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS74749.1 - 0.00011 20.8 0.0 0.00096 17.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 ETS74749.1 - 0.0015 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS74749.1 - 0.0039 17.2 0.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS74749.1 - 0.0063 16.8 0.0 0.34 11.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS74749.1 - 0.012 14.7 0.3 0.52 9.3 0.1 2.5 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 ETS74749.1 - 0.017 13.9 0.2 0.038 12.8 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 ETS74749.1 - 0.017 14.1 0.0 0.04 13.0 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 ETS74749.1 - 0.028 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS74749.1 - 0.035 13.9 0.0 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS74749.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 ETS74749.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 ETS74750.1 - 2.8e-14 52.6 21.8 4.8e-14 51.8 15.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HUN PF08729.5 ETS74750.1 - 0.071 12.9 1.0 0.15 11.9 0.7 1.5 1 0 0 1 1 1 0 HPC2 and ubinuclein domain NmrA PF05368.8 ETS74751.1 - 3.8e-31 108.1 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74751.1 - 7.4e-17 61.9 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS74751.1 - 2.4e-05 23.8 0.0 0.0014 18.1 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS74751.1 - 0.00013 21.9 3.8 0.00027 20.9 0.3 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS74751.1 - 0.0036 16.9 0.6 0.0085 15.7 0.2 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 ETS74751.1 - 0.013 15.9 0.5 0.35 11.3 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 ETS74751.1 - 0.023 13.6 0.0 3.1 6.6 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETS74751.1 - 0.031 13.2 0.0 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.13 ETS74751.1 - 0.046 13.7 0.1 0.93 9.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 ETS74751.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pollen_allerg_1 PF01357.16 ETS74752.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Pollen allergen Sdh5 PF03937.11 ETS74752.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF4632 PF15451.1 ETS74752.1 - 1.9 8.4 4.5 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF3844 PF12955.2 ETS74753.1 - 4.5e-36 123.0 4.0 7.9e-36 122.2 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) UvrD_C_2 PF13538.1 ETS74753.1 - 0.0097 16.0 0.0 0.022 14.8 0.0 1.7 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain EGF_2 PF07974.8 ETS74753.1 - 0.24 11.6 8.0 0.56 10.4 5.5 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 ETS74753.1 - 1 9.4 5.4 2.1 8.3 3.8 1.5 1 0 0 1 1 1 0 EGF-like domain NTR2 PF15458.1 ETS74754.1 - 1.9e-55 187.8 23.8 3.1e-55 187.1 16.5 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF244 PF03112.9 ETS74754.1 - 0.14 11.6 0.6 0.32 10.5 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Hrs_helical PF12210.3 ETS74754.1 - 3.2 8.0 7.3 0.75 10.0 0.4 2.6 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate LSM PF01423.17 ETS74755.1 - 5.4e-19 67.5 0.6 6.2e-19 67.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_23 PF13489.1 ETS74756.1 - 1.1e-27 96.7 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74756.1 - 4.5e-10 39.3 0.0 4.1e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74756.1 - 7.8e-08 32.7 0.0 2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74756.1 - 1e-07 32.5 0.0 3e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS74756.1 - 1.5e-07 31.8 0.0 1.4e-06 28.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS74756.1 - 0.00034 19.7 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase UPF0146 PF03686.8 ETS74756.1 - 0.0031 17.3 0.0 0.95 9.2 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0146) Methyltransf_25 PF13649.1 ETS74756.1 - 0.0091 16.3 0.0 0.032 14.6 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS74756.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 ETS74756.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS74756.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 ETS74756.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 ETS74756.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DZR PF12773.2 ETS74757.1 - 0.19 11.5 1.6 0.35 10.7 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon HET PF06985.6 ETS74758.1 - 1.2e-26 93.5 0.4 2.7e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nop14 PF04147.7 ETS74758.1 - 0.0051 14.8 15.9 0.0063 14.5 11.0 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 ETS74758.1 - 0.048 12.8 13.7 0.071 12.3 9.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CENP-B_dimeris PF09026.5 ETS74758.1 - 0.052 13.7 22.4 0.11 12.7 15.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 ETS74758.1 - 0.25 9.7 19.3 0.34 9.3 13.4 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 ETS74758.1 - 0.29 10.7 12.7 0.52 9.8 8.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 ETS74758.1 - 0.5 9.4 17.4 0.82 8.7 12.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 ETS74758.1 - 0.92 8.1 31.6 1.4 7.5 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 ETS74758.1 - 1.1 7.0 10.6 1.7 6.3 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 ETS74758.1 - 1.9 8.1 5.6 4.1 7.0 3.9 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETS74758.1 - 2.7 5.9 15.2 3.8 5.4 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 ETS74758.1 - 4.1 6.8 16.3 6.9 6.1 11.3 1.3 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.8 ETS74758.1 - 5.3 5.6 11.4 8 5.0 7.9 1.1 1 0 0 1 1 1 0 Paf1 Prothymosin PF03247.9 ETS74758.1 - 5.4 7.2 29.3 10 6.3 20.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family TRAP_alpha PF03896.11 ETS74758.1 - 6.4 5.6 13.7 10 5.0 9.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 ETS74758.1 - 7.2 5.7 18.7 10 5.2 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 ETS74758.1 - 8.8 5.5 20.8 13 4.9 14.4 1.2 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.4 ETS74758.1 - 8.9 4.9 9.2 14 4.3 6.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RXT2_N PF08595.6 ETS74758.1 - 9.4 6.0 13.3 19 5.0 9.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NmrA PF05368.8 ETS74759.1 - 3.1e-32 111.7 0.0 3.8e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74759.1 - 2.4e-12 47.2 0.0 4.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS74759.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 ETS74760.1 - 2e-39 134.5 0.0 2.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS74760.1 - 1.8e-11 43.6 0.0 3.2e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TrkA_N PF02254.13 ETS74760.1 - 0.0022 17.9 0.9 0.31 11.0 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain Gp_dh_N PF00044.19 ETS74760.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 ETS74760.1 - 0.042 14.3 0.4 0.24 11.9 0.2 2.1 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 ETS74760.1 - 0.047 14.1 0.4 0.18 12.2 0.2 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ETS74760.1 - 0.15 12.1 0.2 1.2 9.2 0.1 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PhyH PF05721.8 ETS74761.1 - 5.4e-27 95.2 0.0 8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ODV-E18 PF10717.4 ETS74762.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glyco_hydro_7 PF00840.15 ETS74763.1 - 2.2e-193 642.4 20.7 2.6e-193 642.2 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.3 ETS74763.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Pec_lyase_C PF00544.14 ETS74765.1 - 7.3e-17 61.5 0.9 1.1e-16 60.9 0.6 1.3 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 ETS74766.1 - 4.3e-11 42.1 19.1 5.8e-11 41.7 13.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_28 PF00295.12 ETS74767.1 - 1.7e-36 125.8 3.6 7.5e-36 123.7 2.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pro_isomerase PF00160.16 ETS74768.1 - 8.4e-48 162.4 0.4 9.5e-48 162.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 ETS74768.1 - 0.03 14.1 0.1 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain zf-RING_2 PF13639.1 ETS74769.1 - 2.6e-13 49.5 6.0 4.1e-13 48.9 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS74769.1 - 6.3e-08 32.6 2.4 1.3e-07 31.5 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS74769.1 - 3.2e-07 29.8 3.0 5.1e-07 29.2 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS74769.1 - 1.1e-05 24.9 3.4 1.8e-05 24.3 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS74769.1 - 3.8e-05 23.2 2.0 5.7e-05 22.7 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS74769.1 - 9.5e-05 22.3 4.8 0.00015 21.7 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS74769.1 - 0.0014 18.3 1.4 0.0028 17.4 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETS74769.1 - 0.0051 16.3 6.1 0.0083 15.6 4.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 ETS74769.1 - 0.098 12.3 0.3 0.22 11.2 0.1 1.7 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 ETS74769.1 - 0.16 11.9 2.9 0.41 10.6 2.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 ETS74769.1 - 0.2 11.3 5.2 0.33 10.6 3.6 1.4 1 0 0 1 1 1 0 PHD-finger PSK_trans_fac PF07704.6 ETS74769.1 - 0.5 11.0 6.6 0.13 12.9 1.6 2.3 2 0 0 2 2 1 0 Rv0623-like transcription factor RINGv PF12906.2 ETS74769.1 - 0.57 10.2 5.0 1 9.4 3.5 1.4 1 0 0 1 1 1 0 RING-variant domain DUF3752 PF12572.3 ETS74770.1 - 2.1e-37 128.6 0.5 3.9e-37 127.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) SURF2 PF05477.6 ETS74770.1 - 9.9 5.2 7.1 16 4.5 0.6 2.3 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Vps8 PF12816.2 ETS74771.1 - 2.1e-75 252.3 0.3 1.2e-74 249.7 0.0 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 ETS74771.1 - 2.8e-06 26.9 0.1 0.012 15.1 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 ETS74771.1 - 0.005 16.6 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS74771.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS74771.1 - 0.15 12.1 0.1 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RhgB_N PF09284.5 ETS74772.1 - 1e-71 241.1 6.6 1.6e-71 240.5 4.6 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 ETS74772.1 - 2.8e-47 160.4 1.3 2.8e-47 160.4 0.9 3.3 4 0 0 4 4 4 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 ETS74772.1 - 1.7e-13 50.4 3.1 1.7e-13 50.4 2.1 2.4 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 ETS74772.1 - 0.0047 16.9 1.0 0.0047 16.9 0.7 2.4 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Glyco_hydr_30_2 PF14587.1 ETS74773.1 - 1.2e-18 67.2 5.9 2.3e-18 66.2 4.1 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 CLTH PF10607.4 ETS74774.1 - 5.4e-31 107.2 0.0 1.8e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 ETS74774.1 - 5.9e-15 54.7 1.7 7.2e-15 54.4 0.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 ETS74774.1 - 0.00013 21.2 0.1 0.0002 20.6 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 ETS74774.1 - 0.00061 19.7 0.1 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS74774.1 - 0.0013 18.4 0.2 0.0026 17.5 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS74774.1 - 0.0061 16.2 0.2 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS74774.1 - 0.0085 15.9 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS74774.1 - 0.018 14.7 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS74774.1 - 0.091 12.4 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.13 ETS74775.1 - 0.0017 18.2 0.9 1.2 9.2 0.0 3.3 3 1 0 3 3 3 2 Putative peptidoglycan binding domain ADIP PF11559.3 ETS74775.1 - 0.014 15.2 0.5 0.041 13.7 0.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 ETS74775.1 - 0.15 10.5 3.0 0.21 9.9 2.1 1.1 1 0 0 1 1 1 0 AAA domain PspA_IM30 PF04012.7 ETS74775.1 - 0.19 11.0 4.2 0.12 11.6 0.7 2.0 1 1 0 2 2 2 0 PspA/IM30 family Spo0A_C PF08769.6 ETS74775.1 - 0.19 11.6 1.0 0.42 10.4 0.2 1.9 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal FlaC_arch PF05377.6 ETS74775.1 - 0.25 11.2 0.7 0.69 9.8 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 ETS74775.1 - 0.32 10.8 4.2 0.1 12.4 0.6 1.8 2 0 0 2 2 2 0 Tropomyosin like LETM1 PF07766.8 ETS74776.1 - 1.2e-105 352.4 0.2 1.9e-105 351.7 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 ETS74776.1 - 0.00028 20.3 0.0 0.13 11.7 0.0 2.9 2 1 0 2 2 2 2 SAP domain DSBA PF01323.15 ETS74776.1 - 0.018 14.6 3.1 0.046 13.2 2.1 1.8 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MAPEG PF01124.13 ETS74780.1 - 1.4e-13 50.5 4.0 2.2e-13 49.9 2.8 1.2 1 0 0 1 1 1 1 MAPEG family TEA PF01285.13 ETS74782.1 - 4.2e-11 42.6 8.1 6e-08 32.2 0.1 3.3 4 0 0 4 4 4 2 TEA/ATTS domain family RRM_1 PF00076.17 ETS74783.1 - 2e-73 241.9 2.2 6e-21 73.8 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS74783.1 - 2.8e-60 200.2 0.7 2.2e-14 53.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS74783.1 - 3.4e-34 116.4 0.8 2.8e-09 36.6 0.0 5.8 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS74783.1 - 2.3e-08 33.6 0.1 0.093 12.5 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 ETS74783.1 - 3.1e-07 30.0 1.2 0.0024 17.5 0.0 5.3 5 1 0 5 5 5 1 Limkain b1 Smg4_UPF3 PF03467.10 ETS74783.1 - 7.6e-07 29.2 0.0 0.049 13.6 0.0 3.1 3 0 0 3 3 3 2 Smg-4/UPF3 family RRM_3 PF08777.6 ETS74783.1 - 1.3e-05 24.9 0.9 0.51 10.2 0.0 5.1 4 1 0 4 4 4 1 RNA binding motif Dynein_light PF01221.13 ETS74784.1 - 2e-41 139.8 0.7 2.3e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 ETS74784.1 - 0.047 13.2 0.1 0.07 12.6 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 28 ECM11 PF15463.1 ETS74786.1 - 0.029 14.6 0.4 0.063 13.5 0.3 1.6 1 0 0 1 1 1 0 Extracellular mutant protein 11 MRP-S26 PF14943.1 ETS74786.1 - 0.064 12.8 1.7 0.11 12.0 1.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Med2 PF11214.3 ETS74786.1 - 0.19 11.7 1.2 1.4 9.0 0.5 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 Methyltransf_16 PF10294.4 ETS74787.1 - 5.9e-21 74.6 0.0 1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 ETS74787.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.27 ETS74788.1 - 5.2e-27 92.7 12.4 8.4e-08 31.8 0.1 9.9 10 0 0 10 10 10 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETS74788.1 - 0.00072 18.4 5.8 0.011 14.5 2.0 4.0 4 1 0 4 4 4 1 Nup133 N terminal like Glyco_hydro_47 PF01532.15 ETS74789.1 - 2.2e-134 448.5 0.0 2.8e-134 448.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 ETS74789.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 PA domain Myb_DNA-binding PF00249.26 ETS74790.1 - 0.0079 16.2 2.4 6.8 6.8 0.2 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Zn_clus PF00172.13 ETS74791.1 - 2.4e-06 27.3 9.8 2.4e-06 27.3 6.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bgal_small_N PF02929.12 ETS74791.1 - 0.043 12.8 0.2 0.074 12.0 0.1 1.3 1 0 0 1 1 1 0 Beta galactosidase small chain CorA PF01544.13 ETS74792.1 - 1.3e-13 50.6 0.3 2.4e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF607 PF04678.8 ETS74792.1 - 0.039 13.8 0.2 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF4283 PF14111.1 ETS74792.1 - 0.065 12.3 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) SUR7 PF06687.7 ETS74793.1 - 1e-33 116.7 14.6 1.2e-33 116.4 10.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family RCR PF12273.3 ETS74793.1 - 0.05 14.1 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RAP1 PF07218.6 ETS74793.1 - 1.1 7.2 8.8 1.5 6.8 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.23 ETS74794.1 - 1.4e-38 132.2 0.2 1.9e-38 131.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 ETS74795.1 - 7.4e-42 143.3 24.0 8.6e-42 143.1 16.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74795.1 - 1.3e-13 50.3 7.6 1.3e-13 50.3 5.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS74795.1 - 0.14 10.1 5.4 0.022 12.8 0.4 2.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Isochorismatase PF00857.15 ETS74796.1 - 9.7e-31 107.0 0.0 2.1e-30 105.9 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family HATPase_c PF02518.21 ETS74797.1 - 5.5e-23 80.8 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS74797.1 - 2.5e-21 75.7 0.1 5.3e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 ETS74797.1 - 1.9e-11 44.2 0.1 4.4e-09 36.6 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 ETS74797.1 - 1.6e-08 34.5 0.0 0.00013 22.0 0.0 3.3 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 ETS74797.1 - 2.5e-07 30.5 0.2 2.5e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 ETS74797.1 - 3.7e-07 29.9 0.1 7.4e-06 25.7 0.0 3.2 3 1 0 3 3 3 1 PAS fold PAS_3 PF08447.6 ETS74797.1 - 2.7e-05 24.2 0.1 6.4e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 ETS74797.1 - 0.00026 21.4 0.0 0.073 13.5 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 ETS74797.1 - 0.0021 17.8 0.1 0.022 14.6 0.0 2.8 3 0 0 3 3 3 1 PAS domain GAF_3 PF13492.1 ETS74797.1 - 0.0039 17.2 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 GAF domain Coagulase PF08764.5 ETS74797.1 - 0.17 11.7 0.3 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Aldedh PF00171.17 ETS74800.1 - 2.2e-163 543.9 2.9 2.4e-163 543.7 2.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.14 ETS74802.1 - 3.4e-28 98.1 2.0 4.6e-28 97.7 1.4 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PX PF00787.19 ETS74803.1 - 1.3e-19 70.0 0.1 3.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 ETS74803.1 - 2.4e-10 40.0 11.5 4.1e-06 26.2 1.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 ETS74803.1 - 9.7e-05 21.9 4.8 0.00022 20.8 3.3 1.5 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 ETS74803.1 - 0.0028 16.9 0.2 0.0041 16.3 0.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein FlaC_arch PF05377.6 ETS74803.1 - 0.019 14.8 1.2 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3140 PF11338.3 ETS74803.1 - 0.093 12.8 0.6 0.33 11.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) IncA PF04156.9 ETS74803.1 - 0.31 10.6 5.8 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 IncA protein Peptidase_S8 PF00082.17 ETS74804.1 - 1.1e-53 182.2 2.9 1.7e-53 181.6 2.0 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 ETS74804.1 - 3.1e-30 103.7 0.7 7e-30 102.6 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain FixQ PF05545.6 ETS74804.1 - 0.078 12.6 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_transf_90 PF05686.7 ETS74806.1 - 6.1e-06 25.1 0.4 0.0011 17.6 0.0 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 90 Acetyltransf_7 PF13508.1 ETS74807.1 - 3e-07 30.5 0.0 5.2e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS74807.1 - 9.7e-07 28.7 0.2 2e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS74807.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS74807.1 - 0.024 14.4 0.0 0.076 12.8 0.0 1.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain HET PF06985.6 ETS74808.1 - 4.4e-37 127.3 0.4 8.4e-37 126.4 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS74808.1 - 6.3e-09 36.0 0.2 0.00033 20.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74808.1 - 0.00075 19.1 0.0 7.6 6.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETS74808.1 - 0.0051 17.2 0.6 2.9 8.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF1496 PF07383.7 ETS74809.1 - 0.11 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Glyco_hydro_18 PF00704.23 ETS74811.1 - 3.3e-79 266.8 0.3 5.3e-79 266.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS74811.1 - 9e-09 35.1 9.5 9e-09 35.1 6.6 3.9 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 ETS74812.1 - 3.6e-19 68.3 3.5 0.00013 21.7 0.0 6.9 7 0 0 7 7 7 5 LysM domain HTH_Tnp_1 PF01527.15 ETS74812.1 - 0.023 14.6 0.1 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Transposase DUF2401 PF10287.4 ETS74813.1 - 5e-81 271.6 0.7 1e-80 270.6 0.5 1.5 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 ETS74813.1 - 1e-24 86.4 0.1 8.9e-24 83.4 0.0 2.4 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.4 ETS74813.1 - 0.078 11.2 6.1 0.093 11.0 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 ETS74813.1 - 0.09 12.1 3.0 0.19 11.0 2.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NmrA PF05368.8 ETS74814.1 - 9.8e-61 204.9 0.0 1.1e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74814.1 - 2e-11 44.2 0.0 2.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS74814.1 - 3.5e-07 29.1 0.1 5e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 ETS74814.1 - 0.022 13.7 0.1 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 ETS74814.1 - 0.095 12.1 0.1 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peroxin-13_N PF04088.8 ETS74815.1 - 8.5e-58 194.7 0.0 1.3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 ETS74815.1 - 9e-11 41.1 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS74815.1 - 1.1e-07 31.1 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS74815.1 - 8.9e-07 28.4 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IBN_N PF03810.14 ETS74816.1 - 2.8e-13 49.5 0.4 4.7e-12 45.6 0.4 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain OSCP PF00213.13 ETS74816.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Fungal_trans PF04082.13 ETS74817.1 - 5.5e-06 25.4 0.1 1.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.9 ETS74818.1 - 2.6e-37 128.4 1.2 2.6e-37 128.4 0.9 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 ETS74818.1 - 0.00074 19.3 3.8 0.0015 18.3 2.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS74818.1 - 0.064 12.9 1.6 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Ferric_reduct PF01794.14 ETS74818.1 - 0.092 12.8 2.7 0.17 11.9 1.9 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-C3HC4_2 PF13923.1 ETS74818.1 - 0.47 10.5 8.2 0.32 11.0 2.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1_like PF12832.2 ETS74819.1 - 3.9e-18 65.0 0.1 3.9e-18 65.0 0.1 2.8 3 0 0 3 3 3 1 MFS_1 like family Cytochrom_B558a PF05038.8 ETS74819.1 - 0.024 14.2 2.1 0.052 13.1 1.5 1.6 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.22 ETS74820.1 - 8e-17 61.1 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS74820.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PH_6 PF15406.1 ETS74821.1 - 7.1e-38 129.1 0.8 7.1e-38 129.1 0.6 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.24 ETS74821.1 - 0.004 17.3 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3332 PF11810.3 ETS74821.1 - 2.7 7.6 4.9 0.73 9.4 0.0 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF3332) tRNA-synt_2 PF00152.15 ETS74823.1 - 4.4e-77 259.1 0.0 1.1e-76 257.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS74823.1 - 4.9e-10 39.1 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ETS74823.1 - 2.8e-05 23.4 0.0 0.006 15.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 ETS74823.1 - 0.033 13.7 0.0 9.9 5.7 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 ETS74824.1 - 4.4e-21 73.9 2.1 5.1e-21 73.7 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 ETS74824.1 - 0.014 14.8 1.7 0.017 14.5 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) ADK PF00406.17 ETS74825.1 - 5.9e-38 130.1 0.1 2.6e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 ETS74825.1 - 4.1e-14 51.9 0.0 6.8e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 ETS74825.1 - 1.4e-05 25.3 0.1 0.0047 17.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETS74825.1 - 0.0004 21.1 0.0 0.0011 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS74825.1 - 0.00096 19.0 0.2 0.027 14.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 ETS74825.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 ETS74825.1 - 0.098 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DIOX_N PF14226.1 ETS74826.1 - 9.2e-28 97.1 0.0 1.6e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS74826.1 - 1.2e-18 67.2 0.0 4.4e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ECM11 PF15463.1 ETS74827.1 - 0.17 12.1 2.8 0.4 10.9 2.0 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 ER_lumen_recept PF00810.13 ETS74828.1 - 2.1e-36 125.6 4.9 3.3e-36 124.9 3.4 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Glyco_hydro_76 PF03663.9 ETS74829.1 - 1.2e-22 80.8 2.1 2.5e-13 50.1 0.0 3.3 3 1 0 3 3 3 3 Glycosyl hydrolase family 76 DUF2205 PF10224.4 ETS74830.1 - 0.24 11.0 5.1 0.086 12.4 0.8 2.4 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3720 PF12517.3 ETS74831.1 - 0.59 10.8 2.7 0.65 10.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Dehydratase_hem PF13816.1 ETS74832.1 - 1.8e-78 263.7 0.0 2.6e-78 263.1 0.0 1.2 1 1 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.6 ETS74832.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) YppG PF14179.1 ETS74833.1 - 0.87 10.2 12.2 0.46 11.0 5.8 2.2 2 0 0 2 2 2 0 YppG-like protein Ribosomal_S17 PF00366.15 ETS74834.1 - 6.8e-30 102.9 0.4 1.2e-29 102.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 ETS74835.1 - 1.3e-249 830.9 77.1 1.3e-249 830.9 53.4 2.3 2 1 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 ETS74835.1 - 1.4e-120 401.9 6.8 2.9e-120 400.8 4.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 ETS74835.1 - 1.9e-14 53.0 0.0 3.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 Baculo_PEP_C PF04513.7 ETS74835.1 - 0.062 13.1 0.9 0.17 11.6 0.6 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 ETS74837.1 - 6.1e-42 143.5 4.1 2.3e-24 85.9 0.3 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74837.1 - 7.7e-15 54.6 0.4 3.1e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.6 ETS74839.1 - 2e-14 52.8 0.0 3.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF648 PF04890.8 ETS74839.1 - 0.13 11.4 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Brr6_like_C_C PF10104.4 ETS74840.1 - 8.5e-31 106.2 0.2 1.2e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 ETS74841.1 - 5.8e-27 94.2 1.2 7.2e-27 93.8 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74841.1 - 1.2e-09 37.8 11.3 2.2e-09 37.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 ETS74842.1 - 7.1e-141 470.6 44.5 8.5e-140 467.1 30.9 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein TPR_14 PF13428.1 ETS74842.1 - 0.025 15.1 0.0 0.99 10.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3425 PF11905.3 ETS74843.1 - 8.8e-27 93.6 0.1 1.5e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 ETS74844.1 - 5.6e-19 68.6 0.0 8.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74844.1 - 9.8e-10 38.3 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS74844.1 - 2.1e-06 27.7 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS74844.1 - 0.0004 19.8 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS74844.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding TMEM154 PF15102.1 ETS74845.1 - 0.064 12.9 7.6 0.63 9.7 5.2 2.2 1 1 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.5 ETS74845.1 - 0.23 10.7 0.1 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Med3 PF11593.3 ETS74845.1 - 0.48 9.6 8.1 0.49 9.5 5.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Abhydrolase_5 PF12695.2 ETS74847.1 - 1.9e-11 43.8 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS74847.1 - 3.9e-11 43.2 0.1 5.8e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS74847.1 - 8.3e-05 22.2 0.1 0.00016 21.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 ETS74847.1 - 0.00045 19.8 0.1 0.00079 19.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETS74847.1 - 0.0026 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 ETS74847.1 - 0.004 16.9 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS74847.1 - 0.018 14.2 0.2 0.052 12.7 0.2 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 ETS74847.1 - 0.022 14.5 0.1 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase FAD_binding_3 PF01494.14 ETS74849.1 - 3.2e-87 292.8 0.0 4.2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS74849.1 - 6.7e-50 169.0 0.0 1.5e-49 167.9 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 ETS74849.1 - 1.9e-05 23.3 0.6 3e-05 22.6 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 ETS74849.1 - 0.00015 20.7 0.4 0.00025 20.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS74849.1 - 0.00019 21.4 0.8 0.0026 17.6 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS74849.1 - 0.0015 17.7 0.1 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETS74849.1 - 0.0073 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS74849.1 - 0.014 14.2 0.4 0.022 13.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS74849.1 - 0.032 13.8 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 ETS74849.1 - 0.062 12.3 0.7 0.12 11.4 0.4 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS74849.1 - 0.079 11.8 0.3 0.15 10.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 ETS74849.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS74849.1 - 0.087 13.2 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 ETS74850.1 - 0.00022 21.1 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.11 ETS74851.1 - 3.4e-14 52.3 44.5 3.4e-14 52.3 30.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS74851.1 - 2.8e-05 23.6 6.7 2.8e-05 23.6 4.6 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 ETS74853.1 - 6.1e-10 38.3 0.0 1.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS74853.1 - 3.9e-06 26.6 8.4 8.4e-06 25.6 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.9 ETS74854.1 - 1.4e-25 89.5 0.0 1.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2-Hacid_dh_C PF02826.14 ETS74855.1 - 1.3e-48 164.5 0.0 1.7e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS74855.1 - 1.5e-17 63.2 0.0 2.1e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS74855.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETS74855.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 ETS74856.1 - 8.5e-34 116.7 36.7 8.5e-34 116.7 25.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyt-b5 PF00173.23 ETS74857.1 - 7.9e-15 54.4 0.0 1.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 ETS74858.1 - 1.8e-07 31.1 0.1 6.7e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 FHA domain Herpes_gE PF02480.11 ETS74859.1 - 0.00046 18.5 0.0 0.00052 18.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PXPV PF12778.2 ETS74859.1 - 0.036 13.7 1.1 1.7 8.4 0.0 2.6 2 1 0 2 2 2 0 PXPV repeat (3 copies) adh_short PF00106.20 ETS74861.1 - 9.7e-28 97.1 1.0 2.3e-27 95.9 0.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS74861.1 - 1.4e-10 41.1 1.9 4.5e-09 36.2 1.3 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS74861.1 - 3.4e-09 36.8 0.1 6.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS74861.1 - 6.6e-06 26.2 0.3 9.5e-05 22.4 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding UPF0146 PF03686.8 ETS74861.1 - 0.00012 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) DFP PF04127.10 ETS74861.1 - 0.0018 17.9 0.2 0.0052 16.4 0.0 1.8 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 ETS74861.1 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 ETS74861.1 - 0.009 15.9 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.5 ETS74861.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 ETS74861.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS74861.1 - 0.081 12.3 0.1 0.28 10.5 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VWA_2 PF13519.1 ETS74861.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain HET PF06985.6 ETS74863.1 - 4.1e-33 114.4 1.3 7.2e-33 113.6 0.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) A_deaminase PF00962.17 ETS74866.1 - 1.9e-40 138.8 0.0 2e-39 135.4 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.8 ETS74867.1 - 8.4e-10 38.2 0.0 5.6e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS74867.1 - 2.1e-07 31.1 0.0 5.4e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 ETS74867.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 ETS74867.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 ETS74867.1 - 0.027 13.4 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2881 PF11087.3 ETS74867.1 - 0.064 12.7 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) NAD_binding_7 PF13241.1 ETS74867.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CTP_transf_2 PF01467.21 ETS74868.1 - 2.3e-17 63.4 0.0 1.9e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase PhyH PF05721.8 ETS74869.1 - 2.5e-56 191.0 0.0 3.3e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.17 ETS74870.1 - 9.2e-38 127.7 0.2 3.8e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS74870.1 - 2.4e-29 101.1 0.0 2.6e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS74870.1 - 6.2e-15 54.7 0.0 1.8e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS74870.1 - 0.003 17.2 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Cytomega_UL20A PF05984.7 ETS74870.1 - 0.074 13.2 2.4 0.08 13.1 0.5 1.9 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein RRM_3 PF08777.6 ETS74870.1 - 0.11 12.4 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Bestrophin PF01062.16 ETS74870.1 - 8.9 5.1 6.6 14 4.5 4.6 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RabGAP-TBC PF00566.13 ETS74871.1 - 1.9e-47 161.4 0.0 3.2e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.10 ETS74871.1 - 0.11 12.6 1.4 0.32 11.1 1.0 1.8 1 0 0 1 1 1 0 Cullin binding Aminotran_4 PF01063.14 ETS74872.1 - 3.1e-22 79.1 0.0 4.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SIP1 PF04938.7 ETS74873.1 - 0.11 11.8 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2834 PF11196.3 ETS74876.1 - 0.12 12.5 0.3 0.12 12.5 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) PIR PF00399.14 ETS74877.1 - 0.00028 20.1 0.9 0.00028 20.1 0.6 2.5 2 0 0 2 2 2 1 Yeast PIR protein repeat GST_N_3 PF13417.1 ETS74878.1 - 3.4e-11 43.1 0.2 1.1e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS74878.1 - 4.1e-07 29.7 0.3 1e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS74878.1 - 1e-05 25.9 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS74878.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Aft1_HRA PF11786.3 ETS74879.1 - 5.2e-25 87.5 10.1 5.2e-25 87.5 7.0 2.4 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 ETS74879.1 - 6.1e-18 65.6 6.0 6.1e-18 65.6 4.2 3.3 3 0 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 ETS74879.1 - 1.2e-13 50.8 6.2 1.2e-13 50.8 4.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.3 ETS74879.1 - 3.4e-11 43.4 7.2 2.7e-10 40.5 5.0 2.7 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 ETS74879.1 - 1.2e-06 28.1 6.6 2.1e-06 27.4 4.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS74879.1 - 0.0012 19.0 2.5 0.0028 17.9 1.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.8 ETS74879.1 - 0.047 12.6 2.7 0.071 12.0 1.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HeLo PF14479.1 ETS74879.1 - 0.05 13.3 1.1 0.088 12.5 0.7 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Phlebovirus_NSM PF07246.6 ETS74879.1 - 0.087 11.9 1.6 0.16 11.0 1.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Macoilin PF09726.4 ETS74879.1 - 0.13 10.5 8.0 0.16 10.2 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein MIS13 PF08202.6 ETS74880.1 - 3.2e-59 200.4 0.6 7.9e-59 199.1 0.4 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Sdh5 PF03937.11 ETS74881.1 - 1.5e-23 82.2 0.2 2.9e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase FAM117 PF15388.1 ETS74881.1 - 1 8.5 12.3 1.5 7.9 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM117 EMP24_GP25L PF01105.19 ETS74882.1 - 1.1e-41 142.6 0.0 1.2e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 ETS74882.1 - 0.0082 14.3 0.3 0.011 13.9 0.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4337 PF14235.1 ETS74882.1 - 0.044 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-U1 PF06220.7 ETS74883.1 - 5.2e-22 77.1 3.4 8e-22 76.5 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 ETS74883.1 - 0.021 14.9 3.6 0.046 13.8 2.5 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Arginase PF00491.16 ETS74885.1 - 4.3e-89 298.4 0.0 5.3e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 ETS74885.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 UPF0489 domain RP-C PF03428.8 ETS74886.1 - 0.036 13.5 1.4 0.036 13.5 1.0 1.8 1 1 1 2 2 2 0 Replication protein C N-terminal domain YebF PF13995.1 ETS74886.1 - 0.095 12.7 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 YebF-like protein Beta_helix PF13229.1 ETS74887.1 - 1.8e-09 37.5 18.5 1.4e-06 28.1 10.9 3.0 2 1 0 2 2 2 1 Right handed beta helix region Chondroitinas_B PF14592.1 ETS74887.1 - 2.4e-06 26.6 0.0 4.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 ETS74887.1 - 0.0026 16.9 0.9 0.0026 16.9 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) Golgin_A5 PF09787.4 ETS74888.1 - 4.3 5.7 6.3 5.6 5.3 4.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 GFA PF04828.9 ETS74889.1 - 9e-22 76.8 0.0 1.2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.11 ETS74889.1 - 0.012 15.3 0.3 0.028 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 ETS74889.1 - 0.012 14.8 0.5 0.061 12.5 0.0 2.4 3 0 0 3 3 3 0 zinc-ribbon domain NMD3 PF04981.8 ETS74889.1 - 0.075 12.1 0.5 0.44 9.6 0.0 2.0 1 1 0 2 2 2 0 NMD3 family zinc_ribbon_2 PF13240.1 ETS74889.1 - 0.076 12.5 1.5 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 ETS74889.1 - 0.09 12.6 2.7 0.19 11.5 1.0 2.2 2 1 1 3 3 3 0 Double zinc ribbon CpXC PF14353.1 ETS74889.1 - 0.11 12.4 0.2 5.4 6.9 0.0 2.2 1 1 1 2 2 2 0 CpXC protein Nudix_N_2 PF14803.1 ETS74889.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.8 3 0 0 3 3 3 0 Nudix N-terminal TF_Zn_Ribbon PF08271.7 ETS74889.1 - 0.22 10.8 1.5 1.1 8.5 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 ETS74889.1 - 0.87 9.9 3.7 1.4 9.2 0.7 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar F5_F8_type_C PF00754.20 ETS74890.1 - 1.2e-26 93.0 3.5 3.5e-26 91.5 2.5 1.8 1 0 0 1 1 1 1 F5/8 type C domain DUF1929 PF09118.6 ETS74890.1 - 2.1e-24 85.4 0.3 6.4e-24 83.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 ETS74890.1 - 2.2e-10 40.2 9.4 0.00027 20.9 0.0 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETS74890.1 - 4.6e-09 35.6 1.3 0.02 14.4 1.3 4.7 4 0 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.6 ETS74890.1 - 2e-07 30.3 0.6 0.0059 15.6 0.6 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 ETS74890.1 - 4.6e-06 26.1 0.5 0.016 14.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 ETS74890.1 - 1.1e-05 25.0 10.7 0.0088 15.7 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF1365 PF07103.6 ETS74891.1 - 2.5e-27 95.5 0.0 7e-27 94.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.5 ETS74892.1 - 1.2e-24 86.0 1.5 2.3e-24 85.1 1.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 ETS74892.1 - 3.4e-10 39.6 0.0 6.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 ETS74892.1 - 0.00064 19.8 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 ETS74892.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4226 PF10774.4 ETS74893.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) HET PF06985.6 ETS74894.1 - 2.9e-23 82.5 0.0 5.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT PF03061.17 ETS74896.1 - 1.2e-05 25.3 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 ETS74896.1 - 1.3e-05 25.6 0.0 1.6e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 ETS74896.1 - 0.00013 21.0 0.3 0.0002 20.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.17 ETS74897.1 - 1.6e-29 102.8 0.0 2.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 ETS74897.1 - 0.00078 18.8 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain GFA PF04828.9 ETS74897.1 - 0.029 14.3 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ub-Mut7C PF14451.1 ETS74897.1 - 0.08 12.4 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin PAS_4 PF08448.5 ETS74897.1 - 0.1 12.6 0.1 0.62 10.1 0.0 2.3 3 0 0 3 3 3 0 PAS fold DUF3425 PF11905.3 ETS74898.1 - 3.3e-22 78.8 0.1 6.3e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS74898.1 - 0.012 15.5 12.3 0.1 12.5 8.5 2.1 1 1 0 1 1 1 0 bZIP transcription factor Siah-Interact_N PF09032.6 ETS74898.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal DMPK_coil PF08826.5 ETS74898.1 - 0.079 12.8 3.5 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like ATG16 PF08614.6 ETS74898.1 - 0.2 11.4 7.4 0.35 10.6 5.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 ETS74898.1 - 0.21 11.2 2.4 0.4 10.3 1.7 1.4 1 0 0 1 1 1 0 Mnd1 family Med3 PF11593.3 ETS74898.1 - 0.84 8.8 4.1 3.7 6.7 2.9 1.9 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Amidohydro_1 PF01979.15 ETS74899.1 - 1.4e-17 64.4 0.2 4.1e-14 52.9 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 ETS74899.1 - 4.2e-17 63.0 3.2 5.9e-16 59.3 2.2 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS74899.1 - 5.3e-09 35.7 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS74899.1 - 7.9e-09 35.2 0.9 2.5e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase family A_deaminase PF00962.17 ETS74899.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase PCI PF01399.22 ETS74900.1 - 0.00032 20.9 0.1 0.0016 18.7 0.1 2.1 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.1 ETS74900.1 - 0.0019 17.8 0.0 0.19 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS74900.1 - 0.079 12.9 0.4 0.86 9.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Rep_fac-A_C PF08646.5 ETS74901.1 - 3.2e-56 189.1 4.4 3.4e-54 182.5 0.5 2.8 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 ETS74901.1 - 1.2e-20 73.1 0.0 2.6e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 ETS74901.1 - 7.7e-17 60.9 2.3 4.3e-12 45.7 0.0 4.7 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain Prok-RING_1 PF14446.1 ETS74901.1 - 0.15 11.7 2.4 0.32 10.7 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DLH PF01738.13 ETS74902.1 - 5.2e-20 71.6 0.1 8.5e-18 64.4 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS74902.1 - 3.3e-07 30.1 0.1 6e-07 29.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS74902.1 - 3.4e-05 23.8 0.0 0.019 14.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS74902.1 - 0.0022 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 ETS74903.1 - 1.2e-23 83.1 0.0 1.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS74903.1 - 1.3e-18 68.1 0.0 3e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS74903.1 - 1.7e-11 43.7 0.0 1.1e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4516 PF14990.1 ETS74904.1 - 0.11 12.0 0.8 0.38 10.3 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Glyco_hydro_45 PF02015.11 ETS74905.1 - 4.3e-89 297.9 20.6 5e-89 297.6 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Hydantoinase_B PF02538.9 ETS74906.1 - 2.4e-201 669.5 0.0 4.8e-201 668.5 0.0 1.5 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS74906.1 - 6.5e-95 317.5 0.5 1.6e-94 316.3 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS74906.1 - 3.6e-60 202.4 0.9 2.5e-58 196.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF218 PF02698.12 ETS74908.1 - 5.1e-07 29.3 0.0 9.7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_5 PF12695.2 ETS74909.1 - 5.7e-07 29.3 0.1 8.9e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS74909.1 - 6.9e-05 22.8 0.6 0.00011 22.1 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family SLAC1 PF03595.12 ETS74910.1 - 3.5e-78 262.5 40.0 4.1e-78 262.3 27.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2975 PF11188.3 ETS74910.1 - 0.049 13.3 0.2 0.049 13.3 0.1 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF2975) RseC_MucC PF04246.7 ETS74910.1 - 5.9 6.4 8.2 1.9 8.0 1.0 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Apt1 PF10351.4 ETS74910.1 - 8.7 5.0 7.7 12 4.6 5.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF605 PF04652.11 ETS74910.1 - 9.3 5.5 10.0 12 5.1 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 ETS74911.1 - 6.5e-71 238.5 0.0 1.2e-70 237.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74911.1 - 1e-48 165.7 0.0 2e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS74911.1 - 0.0002 20.4 0.0 0.0039 16.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.7 ETS74913.1 - 0.0064 16.5 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain VWA_2 PF13519.1 ETS74913.1 - 0.048 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Mur_ligase_C PF02875.16 ETS74913.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 ETS74914.1 - 1.8e-74 250.2 0.0 2.5e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS74914.1 - 5.1e-38 130.6 0.0 8.5e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 ETS74914.1 - 8.7e-16 57.8 0.2 2.1e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 ETS74914.1 - 1.5e-06 27.4 0.0 5.9e-06 25.4 0.0 1.8 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS74914.1 - 0.00032 20.0 0.2 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 ETS74914.1 - 0.0015 17.1 0.1 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Glyco_transf_92 PF01697.22 ETS74914.1 - 0.021 14.1 0.2 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 APH PF01636.18 ETS74914.1 - 0.17 11.5 2.2 0.38 10.4 0.3 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DNA_pol_E_B PF04042.11 ETS74916.1 - 2.7e-61 206.4 0.0 3.9e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B GCS PF03074.11 ETS74917.1 - 2.1e-158 527.2 0.0 2.7e-158 526.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 ETS74918.1 - 9.7e-16 56.8 3.4 1.7e-15 56.0 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger MFS_1 PF07690.11 ETS74919.1 - 1.3e-08 34.0 38.3 3.8e-07 29.1 20.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3824 PF12868.2 ETS74922.1 - 0.00014 22.8 43.0 0.00082 20.3 16.0 12.6 5 4 11 16 16 16 5 Domain of unknwon function (DUF3824) Gly-zipper_OmpA PF13436.1 ETS74922.1 - 2.1 8.0 22.1 0.071 12.7 0.4 4.8 3 2 0 4 4 4 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_72 PF03198.9 ETS74923.1 - 1.4e-125 418.4 0.4 1.6e-125 418.2 0.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 ETS74923.1 - 7.4e-08 31.9 0.1 4.1e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.3 ETS74923.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) RTA1 PF04479.8 ETS74924.1 - 4.7e-50 170.1 7.3 4.7e-50 170.1 5.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF378 PF04070.7 ETS74924.1 - 0.0029 17.1 2.5 0.0029 17.1 1.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF378) YqjK PF13997.1 ETS74924.1 - 0.034 14.2 1.0 6.4 7.0 0.0 2.9 2 1 0 2 2 2 0 YqjK-like protein HET PF06985.6 ETS74925.1 - 1e-22 80.8 0.1 2.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_lambd_GpG PF06894.6 ETS74925.1 - 0.016 14.8 0.1 0.042 13.4 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) Cu-oxidase_3 PF07732.10 ETS74926.1 - 1.8e-38 130.9 3.3 1.8e-38 130.9 2.3 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS74926.1 - 5e-37 126.4 10.7 7.1e-37 125.9 0.3 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS74926.1 - 8.8e-37 126.4 2.3 1.4e-35 122.5 0.5 2.5 2 0 0 2 2 2 1 Multicopper oxidase VSP PF03302.8 ETS74927.1 - 7.6e-05 21.5 1.8 7.6e-05 21.5 1.3 1.3 1 1 0 1 1 1 1 Giardia variant-specific surface protein Sporozoite_P67 PF05642.6 ETS74927.1 - 0.03 12.1 7.0 0.037 11.9 4.9 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.5 ETS74927.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.16 ETS74927.1 - 0.67 9.8 3.2 1.6 8.6 2.2 1.7 1 0 0 1 1 1 0 Gram positive anchor RAP1 PF07218.6 ETS74927.1 - 2.8 5.9 5.2 3.4 5.6 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Myticin-prepro PF10690.4 ETS74928.1 - 0.051 13.5 0.6 0.13 12.3 0.4 1.8 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel GMC_oxred_N PF00732.14 ETS74929.1 - 1.7e-62 211.2 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS74929.1 - 6.1e-32 110.8 0.0 1.1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS74929.1 - 1.4e-08 34.0 4.6 0.00033 19.6 2.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS74929.1 - 6.1e-06 26.2 0.1 8.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS74929.1 - 7.6e-05 21.7 6.7 0.0013 17.7 2.3 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS74929.1 - 0.00015 20.9 0.7 0.00015 20.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS74929.1 - 0.0007 18.6 0.7 0.0011 18.0 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS74929.1 - 0.0013 17.8 0.4 0.003 16.6 0.3 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETS74929.1 - 0.0016 18.4 2.2 0.0025 17.8 0.7 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS74929.1 - 0.0036 16.2 0.7 0.0059 15.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS74929.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS74929.1 - 0.02 13.4 2.1 0.032 12.7 1.4 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 ETS74929.1 - 0.13 11.7 0.6 0.25 10.7 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 ETS74929.1 - 0.19 9.9 0.0 0.36 9.0 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.2 ETS74929.1 - 0.27 10.2 6.4 0.52 9.3 3.9 1.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase ThiF PF00899.16 ETS74929.1 - 0.46 10.2 2.1 1.2 8.8 1.4 1.7 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 ETS74929.1 - 1.4 7.4 4.3 2.1 6.8 3.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 ETS74930.1 - 3.8e-13 49.2 1.3 2.8e-05 23.3 0.2 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 ETS74930.1 - 0.00017 20.6 0.0 0.00064 18.7 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS74930.1 - 0.00081 19.7 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS74930.1 - 0.0023 17.9 0.1 0.0064 16.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS74930.1 - 0.0023 16.8 0.4 0.0044 15.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS74930.1 - 0.0088 14.5 0.3 0.013 13.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Mvb12 PF09452.5 ETS74930.1 - 0.016 15.4 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Pyr_redox_2 PF07992.9 ETS74930.1 - 0.049 13.5 0.1 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tox-HNH-HHH PF15637.1 ETS74932.1 - 0.1 12.3 1.2 12 5.7 0.0 2.3 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif ketoacyl-synt PF00109.21 ETS74933.1 - 3.7e-67 226.4 0.3 7.5e-67 225.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS74933.1 - 1e-55 188.2 0.1 2.9e-55 186.7 0.1 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 ETS74933.1 - 1.6e-50 172.2 0.3 7.9e-50 169.9 0.2 2.0 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS74933.1 - 3.8e-43 147.3 0.1 1.4e-42 145.4 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS74933.1 - 2e-35 121.2 0.0 8.6e-35 119.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 ETS74933.1 - 2.1e-35 122.3 0.0 4.4e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 ETS74933.1 - 2.9e-17 62.9 0.0 1.3e-16 60.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74933.1 - 8.8e-12 44.8 0.0 8.1e-10 38.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74933.1 - 1.3e-10 41.2 0.0 3.7e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74933.1 - 3.7e-09 36.9 0.0 1.2e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74933.1 - 6e-08 33.2 0.0 2.6e-06 28.0 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 ETS74933.1 - 1.5e-06 28.3 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 ETS74933.1 - 0.00018 21.8 0.0 0.0012 19.1 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS74933.1 - 0.0021 17.2 0.0 0.0051 15.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 ETS74933.1 - 0.0051 15.8 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 ETS74933.1 - 0.039 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 ETS74933.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase HET PF06985.6 ETS74934.1 - 1.4e-14 54.4 1.6 1.4e-13 51.2 0.8 2.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ead_Ea22 PF13935.1 ETS74934.1 - 1.6 9.0 6.6 3 8.1 3.0 2.5 1 1 1 2 2 2 0 Ead/Ea22-like protein HET PF06985.6 ETS74937.1 - 3.1e-24 85.6 2.1 6e-24 84.7 1.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OTT_1508_deam PF14441.1 ETS74938.1 - 1e-06 28.6 0.0 1.5e-05 24.8 0.0 2.4 1 1 1 2 2 2 1 OTT_1508-like deaminase Ornatin PF02088.10 ETS74939.1 - 0.29 10.7 3.9 0.65 9.6 2.7 1.7 1 0 0 1 1 1 0 Ornatin DUF1233 PF06806.7 ETS74940.1 - 0.096 12.2 0.3 4.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Putative excisionase (DUF1233) GATase_7 PF13537.1 ETS74940.1 - 0.11 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain Asp_Glu_race PF01177.17 ETS74941.1 - 5.6e-29 101.6 0.1 6.4e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fructosamin_kin PF03881.9 ETS74942.1 - 6.3e-34 117.2 0.0 7.8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS74942.1 - 9e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DSHCT PF08148.7 ETS74943.1 - 2.9e-61 205.8 0.5 5.2e-61 205.0 0.4 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 ETS74943.1 - 1.7e-20 73.1 0.0 3.8e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS74943.1 - 2.9e-06 27.0 0.9 9.4e-06 25.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 ETS74943.1 - 0.0004 19.6 0.0 0.00089 18.4 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Swi3 PF07962.7 ETS74944.1 - 2e-29 101.0 0.2 5e-29 99.7 0.2 1.7 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.4 ETS74945.1 - 8.5e-34 115.6 0.8 1.4e-33 115.0 0.6 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 ETS74945.1 - 5.9e-28 96.4 0.0 8.3e-28 95.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Fungal_trans PF04082.13 ETS74946.1 - 2e-15 56.3 0.8 5.3e-15 54.9 0.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.13 ETS74947.1 - 3.7e-81 272.7 0.2 7.4e-48 163.1 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS74947.1 - 0.0013 17.7 0.2 0.0033 16.3 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS74947.1 - 0.0029 16.6 0.1 0.0085 15.0 0.1 1.7 1 1 1 2 2 2 1 Conserved region in glutamate synthase Peptidase_M19 PF01244.16 ETS74947.1 - 0.014 14.3 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DHO_dh PF01180.16 ETS74947.1 - 0.031 13.2 0.2 4.4 6.1 0.0 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Snf7 PF03357.16 ETS74948.1 - 3.7e-08 32.9 21.7 3.7e-08 32.9 15.0 1.6 1 1 1 2 2 2 1 Snf7 MS_channel PF00924.13 ETS74948.1 - 0.039 13.2 0.4 0.062 12.6 0.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel Ist1 PF03398.9 ETS74948.1 - 0.052 12.9 6.1 0.29 10.5 4.3 2.0 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway SATase_N PF06426.9 ETS74948.1 - 1.1 9.5 6.7 4.9 7.4 4.6 2.2 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF1451 PF07295.6 ETS74948.1 - 7.3 6.3 8.3 2.7 7.7 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF427 PF04248.7 ETS74949.1 - 6.6e-29 99.4 0.0 8.2e-29 99.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pro-rich_19 PF15455.1 ETS74949.1 - 0.05 12.6 0.6 0.054 12.5 0.4 1.0 1 0 0 1 1 1 0 Proline-rich 19 Sugar_tr PF00083.19 ETS74950.1 - 2.9e-78 263.4 27.8 3.2e-78 263.3 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74950.1 - 3.4e-27 95.0 25.1 2.1e-25 89.2 16.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 ETS74951.1 - 6.7e-37 127.0 12.9 2.6e-19 69.1 5.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS74951.1 - 1.9e-07 30.0 17.5 4.1e-05 22.3 5.4 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter DUF791 PF05631.9 ETS74951.1 - 0.00095 17.9 0.9 0.0017 17.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 ETS74951.1 - 0.0013 18.4 2.0 0.13 12.0 0.4 2.6 2 0 0 2 2 2 2 MFS_1 like family Folate_carrier PF01770.13 ETS74951.1 - 0.016 13.7 0.1 0.016 13.7 0.1 1.8 2 0 0 2 2 2 0 Reduced folate carrier MFS_3 PF05977.8 ETS74951.1 - 0.043 11.9 13.6 0.12 10.4 2.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 ETS74951.1 - 0.071 11.1 4.7 1.2 7.1 0.1 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 ETS74952.1 - 4e-55 187.1 0.0 5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.17 ETS74952.1 - 0.14 11.4 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) zf-RING_2 PF13639.1 ETS74954.1 - 1.1e-13 50.7 6.0 1.8e-13 50.0 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 ETS74954.1 - 6.4e-13 48.2 0.0 1.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 ETS74954.1 - 3.3e-09 36.5 5.6 5.9e-09 35.8 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS74954.1 - 8.8e-09 35.3 3.1 1.6e-08 34.5 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS74954.1 - 2.1e-08 33.7 3.5 3.4e-08 32.9 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS74954.1 - 1e-07 31.4 3.3 1.7e-07 30.7 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS74954.1 - 2.7e-07 30.2 2.7 4.3e-07 29.5 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETS74954.1 - 0.0011 18.7 0.9 0.002 17.9 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETS74954.1 - 0.04 13.7 4.1 0.14 12.1 3.0 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 ETS74954.1 - 0.14 12.2 3.9 0.26 11.3 2.7 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 ETS74954.1 - 0.16 11.9 2.7 0.42 10.6 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 ETS74954.1 - 0.24 11.1 3.0 0.56 9.9 2.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 ETS74954.1 - 0.42 10.2 2.4 0.88 9.1 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 ETS74954.1 - 0.58 10.1 3.7 1.1 9.2 2.5 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 ETS74954.1 - 1.3 8.7 3.1 2.4 7.8 2.1 1.5 1 0 0 1 1 1 0 PHD-finger p450 PF00067.17 ETS74955.1 - 2.6e-66 224.0 0.0 3.2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 ETS74956.1 - 1.8e-123 412.4 20.9 2.1e-123 412.2 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74956.1 - 2.2e-20 72.6 36.4 1.6e-19 69.8 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 ETS74956.1 - 0.018 14.0 7.6 0.041 12.9 5.3 1.6 1 0 0 1 1 1 0 Emopamil binding protein 7tm_1 PF00001.16 ETS74956.1 - 0.053 12.6 6.9 1.2 8.2 0.5 2.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.7 ETS74956.1 - 0.59 10.1 0.0 0.59 10.1 0.0 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3154 PF11351.3 ETS74956.1 - 0.61 9.8 2.6 3.5 7.3 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Rft-1 PF04506.8 ETS74957.1 - 2.4e-91 306.7 4.8 2.9e-91 306.5 3.3 1.0 1 0 0 1 1 1 1 Rft protein DEAD PF00270.24 ETS74958.1 - 1.2e-46 158.3 0.0 6.5e-45 152.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS74958.1 - 6.1e-28 96.5 0.1 3e-27 94.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIF_alpha PF05793.7 ETS74958.1 - 0.00085 17.8 40.2 0.0012 17.3 27.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 ETS74958.1 - 0.0014 17.0 4.5 0.0013 17.1 3.1 1.1 1 0 0 1 1 1 1 Transmembrane protein CMS1 PF14617.1 ETS74958.1 - 0.0079 15.2 0.0 0.0079 15.2 0.0 4.1 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit MIP-T3 PF10243.4 ETS74958.1 - 0.02 13.3 34.5 0.026 13.0 23.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1253 PF06862.7 ETS74958.1 - 0.084 11.2 0.0 0.084 11.2 0.0 2.9 5 1 0 5 5 5 0 Protein of unknown function (DUF1253) Borrelia_P83 PF05262.6 ETS74958.1 - 3.2 5.9 30.8 5 5.2 21.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Daxx PF03344.10 ETS74958.1 - 5.1 5.4 27.4 6.5 5.1 19.0 1.1 1 0 0 1 1 1 0 Daxx Family HORMA PF02301.13 ETS74959.1 - 6.9e-47 159.6 0.0 8e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Tox-MPTase3 PF15639.1 ETS74959.1 - 0.0064 16.2 0.5 0.23 11.1 0.2 2.5 2 1 0 2 2 2 1 Metallopeptidase toxin 3 Glyco_hydro_2_C PF02836.12 ETS74961.1 - 2.5e-83 279.4 0.1 3.2e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 ETS74961.1 - 3.8e-39 133.9 0.1 5.9e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS74961.1 - 4.1e-10 40.0 0.0 1.1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.1 ETS74961.1 - 0.00029 20.6 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase-like PF12876.2 ETS74961.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Sugar-binding cellulase-like Sugar_tr PF00083.19 ETS74962.1 - 1e-73 248.5 28.4 1.2e-73 248.3 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS74962.1 - 3.2e-20 72.1 32.1 3.2e-20 72.1 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 ETS74965.1 - 2.7e-58 197.6 0.0 3.5e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 ETS74966.1 - 1.2e-06 28.3 9.3 2.4e-06 27.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FANCI_S3 PF14677.1 ETS74966.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Abhydrolase_6 PF12697.2 ETS74967.1 - 5.2e-21 75.5 0.0 6.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS74967.1 - 1.9e-06 27.6 0.0 3.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS74967.1 - 1e-05 25.1 0.0 0.00032 20.3 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 ETS74967.1 - 0.026 14.1 0.1 0.059 12.9 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase Ank_2 PF12796.2 ETS74968.1 - 3.8e-32 110.4 5.0 1.1e-12 48.1 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS74968.1 - 6.8e-19 66.6 7.0 7.3e-05 22.3 0.0 10.0 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 ETS74968.1 - 1.4e-18 66.4 0.2 1e-06 28.7 0.0 6.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS74968.1 - 7.1e-18 62.9 0.7 4.8e-05 23.2 0.0 8.8 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.1 ETS74968.1 - 4.6e-17 62.0 0.7 1.4e-07 31.8 0.0 6.1 6 1 1 7 7 7 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 ETS74968.1 - 1.6e-13 50.1 0.0 3.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 ETS74968.1 - 3.8e-09 36.4 0.0 1.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS74968.1 - 0.00037 20.5 0.8 0.0019 18.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain HemY_N PF07219.8 ETS74968.1 - 0.0094 15.4 2.7 1.2 8.7 0.1 3.4 3 0 0 3 3 3 1 HemY protein N-terminus AAA_22 PF13401.1 ETS74968.1 - 0.015 15.4 0.0 0.09 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 ETS74969.1 - 6.5e-20 71.0 4.7 1.4e-19 69.9 3.3 1.6 1 0 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.20 ETS74970.1 - 3.9e-10 39.8 0.1 5.8e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS74970.1 - 7.4e-08 32.9 0.0 1.1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETS74970.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.7 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 ETS74970.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 CppA N-terminal HET PF06985.6 ETS74971.1 - 1.6e-15 57.5 10.4 4.3e-13 49.6 1.8 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS74972.1 - 2e-32 112.2 0.0 5e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3848 PF12959.2 ETS74972.1 - 0.049 13.5 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) HET PF06985.6 ETS74973.1 - 1.1e-18 67.7 0.0 3.2e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C39_2 PF13529.1 ETS74974.1 - 0.028 14.7 0.0 0.13 12.6 0.0 2.1 1 1 1 2 2 2 0 Peptidase_C39 like family DUF427 PF04248.7 ETS74974.1 - 0.04 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FAD_binding_4 PF01565.18 ETS74975.1 - 2.2e-17 62.8 1.0 4.2e-17 61.9 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS74975.1 - 5.4e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.16 ETS74975.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase DUF2306 PF10067.4 ETS74978.1 - 5.9e-12 45.6 3.5 1.3e-11 44.5 2.4 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF4486 PF14858.1 ETS74978.1 - 0.096 10.9 0.1 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) Lipase_GDSL_2 PF13472.1 ETS74979.1 - 1.4e-28 100.2 6.8 1.6e-17 64.2 1.9 2.9 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family VCBS PF13517.1 ETS74979.1 - 8.3e-25 86.9 50.4 8.3e-10 38.8 5.0 6.2 3 2 3 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS74979.1 - 9.1e-16 57.0 34.9 0.00059 19.4 0.9 6.5 6 0 0 6 6 6 5 FG-GAP repeat Lipase_GDSL PF00657.17 ETS74979.1 - 3.1e-14 53.3 1.2 3.1e-14 53.3 0.8 2.4 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 ETS74979.1 - 9.6e-08 31.6 9.8 0.39 10.1 0.1 5.0 4 1 1 5 5 5 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 ETS74979.1 - 0.00024 20.8 0.0 0.00072 19.3 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HET PF06985.6 ETS74980.1 - 6.6e-38 130.0 1.4 2.1e-37 128.3 0.7 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2236 PF09995.4 ETS74981.1 - 4e-05 23.0 0.1 0.00011 21.6 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PIG-S PF10510.4 ETS74982.1 - 3.9e-151 504.2 2.5 4.6e-151 504.0 1.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein PAN_3 PF08277.7 ETS74983.1 - 0.0081 15.7 0.3 0.031 13.8 0.2 2.0 1 0 0 1 1 1 1 PAN-like domain AMP-binding PF00501.23 ETS74984.1 - 6e-72 242.3 0.0 7.7e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS74984.1 - 2.1e-09 38.2 0.0 4.4e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2577 PF10844.3 ETS74984.1 - 0.014 15.4 0.2 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Diphthamide_syn PF01866.12 ETS74985.1 - 4.6e-47 160.7 0.0 9.6e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Putative diphthamide synthesis protein GSH_synth_ATP PF03917.12 ETS74986.1 - 6.2e-100 334.3 0.0 7.6e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 ETS74986.1 - 7.4e-30 103.1 0.0 3.1e-29 101.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic glutathione synthase DAO PF01266.19 ETS74988.1 - 1.3e-30 106.4 0.1 2.4e-30 105.6 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS74988.1 - 5.7e-05 23.0 0.1 0.00031 20.7 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS74988.1 - 0.00017 21.9 0.0 0.0082 16.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS74988.1 - 0.00085 18.2 0.0 0.057 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 ETS74988.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS74988.1 - 0.028 13.3 0.1 0.052 12.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 ETS74988.1 - 0.029 13.4 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 ETS74988.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETS74988.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.1 3 0 0 3 3 3 0 Putative NAD(P)-binding GDI PF00996.13 ETS74988.1 - 0.23 9.7 0.0 0.66 8.2 0.0 1.7 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_9 PF13454.1 ETS74989.1 - 3e-37 127.8 0.0 4.8e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS74989.1 - 5.2e-06 26.6 0.0 8.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS74989.1 - 0.00032 19.7 0.0 0.099 11.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS74989.1 - 0.0069 15.3 0.0 0.056 12.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Cu-oxidase_2 PF07731.9 ETS74991.1 - 2.7e-41 140.3 10.6 5.4e-41 139.3 1.2 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS74991.1 - 2.6e-39 133.5 3.3 2.6e-39 133.5 2.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS74991.1 - 2.3e-35 121.8 3.1 3.1e-34 118.1 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 ETS74992.1 - 3.5e-38 131.2 42.2 1.3e-36 126.0 21.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_H PF00075.19 ETS74993.1 - 8.6e-11 42.3 0.0 1.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 RNase H Asp PF00026.18 ETS74995.1 - 5.1e-65 219.8 11.2 6.9e-65 219.3 7.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS74995.1 - 2.3e-08 34.1 8.7 2.9e-08 33.8 2.4 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS74995.1 - 0.0031 17.9 0.6 4.2 7.9 0.3 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 ETS74995.1 - 0.017 14.9 0.2 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 ETS74995.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 ETS74996.1 - 1.6e-33 115.8 43.8 3.2e-32 111.6 30.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS74996.1 - 7.1e-16 57.5 16.9 1.1e-15 56.9 11.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS74996.1 - 6.4e-13 48.0 10.7 6.4e-13 48.0 7.4 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter GMC_oxred_N PF00732.14 ETS74997.1 - 9.6e-56 189.0 0.0 1.3e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS74997.1 - 8.2e-33 113.7 0.2 1.3e-32 113.1 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS74997.1 - 3.3e-09 36.1 2.2 2.9e-08 33.0 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS74997.1 - 8.4e-05 22.5 0.1 0.00055 19.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS74997.1 - 9.2e-05 21.5 0.1 0.00056 18.9 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS74997.1 - 0.011 14.5 1.0 0.057 12.2 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS74997.1 - 0.018 14.8 0.2 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS74997.1 - 0.022 13.6 0.4 1.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS74997.1 - 0.024 14.6 0.1 0.96 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS74997.1 - 0.053 13.9 0.0 0.37 11.2 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS74997.1 - 0.064 13.0 0.3 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_12 PF08242.7 ETS74998.1 - 5.5e-11 42.8 0.0 9.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS74998.1 - 1e-10 41.9 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS74998.1 - 4.2e-10 39.4 0.0 5.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS74998.1 - 1.4e-09 38.2 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS74998.1 - 1.9e-08 34.8 0.0 8.3e-08 32.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS74998.1 - 4.8e-06 26.3 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS74998.1 - 6.7e-06 25.3 0.0 9.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS74998.1 - 3.4e-05 23.8 0.0 7.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETS74998.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 ETS74998.1 - 0.022 13.8 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 ETS74998.1 - 0.042 12.8 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.20 ETS74999.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1485 PF07364.7 ETS74999.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) DUF3328 PF11807.3 ETS75000.1 - 7.3e-46 156.5 2.5 9e-46 156.2 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3733 PF12534.3 ETS75001.1 - 0.046 13.0 0.3 0.046 13.0 0.2 2.7 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 DUF2614 PF11023.3 ETS75001.1 - 7.7 6.3 10.7 0.71 9.6 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) FAD_binding_4 PF01565.18 ETS75002.1 - 2.2e-20 72.5 6.1 3.5e-20 71.9 4.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS75002.1 - 2.9e-06 27.0 0.8 6.6e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_3 PF01494.14 ETS75003.1 - 2.2e-17 63.1 0.4 1.2e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS75003.1 - 3.4e-09 36.0 0.5 0.00014 20.9 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS75003.1 - 3.2e-05 23.1 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 ETS75003.1 - 0.00024 19.7 0.1 0.00032 19.2 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS75003.1 - 0.00047 20.1 0.3 0.0011 18.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS75003.1 - 0.00079 19.7 0.2 0.002 18.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS75003.1 - 0.0013 17.8 0.6 0.0029 16.7 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS75003.1 - 0.002 17.0 0.9 0.0035 16.2 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS75003.1 - 0.028 13.4 0.2 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 ETS75003.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ketoacyl-synt_C PF02801.17 ETS75004.1 - 7.7e-33 112.8 0.1 1.1e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 ETS75004.1 - 3.2e-25 89.0 0.5 5.7e-13 48.9 0.1 2.2 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 ETS75005.1 - 0.009 14.8 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 2 Condensation domain Peptidase_C48 PF02902.14 ETS75006.1 - 2.1e-05 24.2 0.1 5.2e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MFS_1 PF07690.11 ETS75007.1 - 5.7e-31 107.5 69.9 2.3e-24 85.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS75007.1 - 6e-05 21.7 42.3 0.0032 16.1 12.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS75007.1 - 0.017 14.8 9.1 0.049 13.4 4.5 2.8 2 0 0 2 2 2 0 MFS_1 like family TPR_12 PF13424.1 ETS75008.1 - 1.6e-12 47.1 30.2 9.3e-05 22.2 0.5 9.6 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS75008.1 - 1.1e-07 32.1 15.0 0.024 14.9 0.0 8.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS75008.1 - 5e-06 25.9 17.8 2.8 7.9 0.1 9.4 8 0 0 8 8 8 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETS75008.1 - 3.3e-05 24.0 3.1 6.1e-05 23.1 0.1 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 ETS75008.1 - 0.0019 17.9 0.1 0.0075 15.9 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.1 ETS75008.1 - 0.0038 17.5 16.1 0.37 11.3 0.2 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS75008.1 - 0.0045 16.6 10.1 7.3 6.6 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS75008.1 - 0.046 13.6 28.7 3.4 7.7 0.0 9.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS75008.1 - 0.37 10.8 14.0 15 5.8 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS75008.1 - 3.4 8.5 28.2 15 6.5 0.0 10.3 12 0 0 12 12 12 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 ETS75009.1 - 3.8e-55 186.2 0.1 7.2e-55 185.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 ETS75009.1 - 2.2e-31 107.4 0.0 4.2e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 ETS75009.1 - 1.1e-30 105.5 0.0 2.8e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETS75009.1 - 2.3e-22 78.6 0.0 6.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS75009.1 - 8.9e-13 48.1 0.0 2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF148 PF02520.12 ETS75009.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 SDH_alpha PF03313.10 ETS75010.1 - 3.2e-90 302.0 2.9 5e-90 301.3 2.0 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 ETS75010.1 - 2.4e-50 170.6 0.0 6.1e-50 169.3 0.0 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain Sugar_tr PF00083.19 ETS75011.1 - 1e-71 241.8 25.1 1.2e-71 241.6 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75011.1 - 6.5e-20 71.1 27.5 6.5e-20 71.1 19.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS75011.1 - 0.00019 19.9 2.5 0.00019 19.9 1.7 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein ADH_zinc_N_2 PF13602.1 ETS75012.1 - 9e-19 68.6 0.0 2.4e-18 67.2 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS75012.1 - 9.6e-18 63.9 0.0 2.5e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DFP PF04127.10 ETS75012.1 - 7.4e-05 22.4 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF2855 PF11017.3 ETS75012.1 - 0.00011 21.4 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DapB_N PF01113.15 ETS75012.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 ETS75012.1 - 0.00058 19.3 0.1 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS75012.1 - 0.0011 18.9 0.3 0.0019 18.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS75012.1 - 0.0037 17.0 0.6 0.0073 16.0 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.7 ETS75012.1 - 0.0059 16.3 0.0 0.064 13.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.14 ETS75012.1 - 0.018 14.1 0.1 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 ETS75012.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETS75012.1 - 0.026 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain ELFV_dehydrog PF00208.16 ETS75012.1 - 0.041 13.4 0.5 0.058 12.9 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 ETS75012.1 - 0.043 13.8 0.1 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding PGM_PMM_II PF02879.11 ETS75012.1 - 0.05 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II NAD_binding_3 PF03447.11 ETS75012.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 ETS75014.1 - 3.3e-51 174.0 4.8 3.3e-51 174.0 3.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75014.1 - 2.2e-08 33.8 9.0 5e-08 32.7 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.10 ETS75015.1 - 4e-33 114.4 4.9 6.1e-33 113.8 3.4 1.3 1 0 0 1 1 1 1 Ctr copper transporter family SRP_SPB PF02978.14 ETS75015.1 - 0.29 11.4 5.4 0.48 10.6 3.7 1.4 1 0 0 1 1 1 0 Signal peptide binding domain Hemerythrin PF01814.18 ETS75016.1 - 1e-08 35.3 0.1 1.4e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain APOC4 PF15119.1 ETS75017.1 - 0.13 12.2 0.8 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein C4 Ank PF00023.25 ETS75018.1 - 1.7e-72 235.7 17.0 3.5e-10 39.1 0.0 9.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_2 PF12796.2 ETS75018.1 - 2.4e-72 239.3 1.3 2.2e-18 66.3 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS75018.1 - 9.7e-48 155.3 11.0 9.8e-07 28.4 0.0 9.6 10 0 0 10 10 8 7 Ankyrin repeat Ank_5 PF13857.1 ETS75018.1 - 9.1e-47 156.0 13.8 8.8e-10 38.5 0.1 8.4 3 1 6 9 9 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS75018.1 - 1.9e-43 146.0 15.0 3.3e-10 40.2 0.1 7.3 2 1 6 8 8 7 7 Ankyrin repeats (many copies) NACHT PF05729.7 ETS75018.1 - 9.7e-07 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS75018.1 - 4.8e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS75018.1 - 9.3e-05 22.4 1.1 0.00022 21.2 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 ETS75018.1 - 0.0028 16.6 0.3 0.026 13.5 0.1 2.0 2 0 0 2 2 2 1 KAP family P-loop domain AAA_17 PF13207.1 ETS75018.1 - 0.031 15.0 0.5 0.21 12.4 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS75018.1 - 0.039 13.3 0.1 0.24 10.7 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 ETS75018.1 - 0.043 13.7 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 ETS75018.1 - 0.087 13.1 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS75018.1 - 0.093 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 ETS75018.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 ETS75018.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 ETS75018.1 - 0.23 11.6 0.0 0.5 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 ETS75018.1 - 0.23 10.8 0.1 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HET PF06985.6 ETS75019.1 - 2.2e-21 76.4 0.0 6e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_1 PF00087.16 ETS75021.1 - 0.023 15.0 0.1 0.074 13.4 0.1 2.0 1 0 0 1 1 1 0 Snake toxin CAF-1_p150 PF11600.3 ETS75022.1 - 0.46 9.8 51.4 0.53 9.6 35.6 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 ETS75022.1 - 6.9 5.9 30.1 7.7 5.8 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) EF1_GNE PF00736.14 ETS75023.1 - 6.1e-29 99.5 3.4 1e-28 98.8 2.3 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 ETS75023.1 - 6.4e-11 42.1 4.8 1.6e-10 40.9 3.3 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Zip PF02535.17 ETS75024.1 - 3.7e-46 157.5 4.1 5.2e-46 157.1 2.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_18 PF00704.23 ETS75025.1 - 8.2e-44 150.4 0.4 1.3e-43 149.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 ETS75025.1 - 3.4e-20 71.7 1.7 1.1e-19 70.0 1.1 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.14 ETS75025.1 - 0.00018 21.4 4.1 0.00018 21.4 2.8 2.9 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 ETS75025.1 - 0.00057 19.7 0.2 0.25 11.2 0.0 2.7 2 0 0 2 2 2 2 LysM domain Acetyltransf_3 PF13302.1 ETS75026.1 - 5.7e-12 45.9 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS75026.1 - 0.00069 19.5 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS75026.1 - 0.017 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS75026.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 ETS75027.1 - 1.4e-25 89.4 0.0 2.2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS75027.1 - 0.04 13.8 0.2 0.088 12.7 0.2 1.5 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.20 ETS75028.1 - 2.1e-12 47.2 0.5 3.9e-12 46.4 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75028.1 - 8.2e-08 32.1 0.2 1.2e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS75028.1 - 0.0019 18.2 0.1 0.0098 15.9 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 ETS75028.1 - 0.0027 17.5 0.1 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS75028.1 - 0.033 13.6 0.2 0.066 12.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS75028.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Chitin_synth_1 PF01644.12 ETS75029.1 - 4.7e-67 224.8 0.0 6.9e-67 224.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 ETS75029.1 - 1.2e-27 96.5 0.1 6.7e-23 80.8 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 ETS75029.1 - 3.7e-24 84.2 0.3 9.5e-24 82.9 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 ETS75029.1 - 3e-11 43.3 4.2 1.8e-10 40.8 2.9 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS75029.1 - 1.3e-07 31.6 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF716 PF04819.7 ETS75030.1 - 0.37 10.2 3.1 0.56 9.6 2.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF716) NMT_C PF02799.10 ETS75031.1 - 4.3e-78 261.0 0.2 7.6e-78 260.2 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 ETS75031.1 - 8e-73 243.3 0.1 1.6e-72 242.4 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 ETS75031.1 - 9.8e-05 22.2 0.1 0.004 17.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS75031.1 - 0.0016 18.5 0.2 0.0061 16.7 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NST1 PF13945.1 ETS75031.1 - 2.1 8.3 8.5 0.43 10.6 2.9 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator Bac_luciferase PF00296.15 ETS75032.1 - 1.2e-66 224.9 0.3 1.4e-66 224.6 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abhydrolase_6 PF12697.2 ETS75033.1 - 6.1e-25 88.4 0.0 9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS75033.1 - 8.6e-13 48.3 0.0 1.9e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS75033.1 - 5.5e-12 45.6 0.0 1.5e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS75033.1 - 8.9e-07 28.5 0.0 0.0095 15.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 ETS75033.1 - 2.7e-05 23.4 0.1 0.011 14.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family UPF0227 PF05728.7 ETS75033.1 - 9.5e-05 22.1 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 ETS75033.1 - 0.0003 20.6 0.0 0.0012 18.7 0.0 2.0 1 1 1 2 2 2 1 TAP-like protein DUF2048 PF09752.4 ETS75033.1 - 0.00041 19.3 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) DUF1100 PF06500.6 ETS75033.1 - 0.003 16.1 0.0 0.0042 15.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase_phd PF10503.4 ETS75033.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.13 ETS75033.1 - 0.12 11.6 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 ETS75033.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Methyltransf_2 PF00891.13 ETS75034.1 - 5.1e-31 107.7 0.0 1.4e-30 106.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase NmrA PF05368.8 ETS75035.1 - 1.5e-18 66.9 0.0 1.9e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS75035.1 - 8.6e-16 58.4 0.4 1.2e-15 58.0 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS75035.1 - 4.1e-06 26.4 0.0 7.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GARS_N PF02844.10 ETS75035.1 - 0.0028 18.0 0.1 0.0092 16.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain Saccharop_dh PF03435.13 ETS75035.1 - 0.0037 16.3 0.2 0.0067 15.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 ETS75035.1 - 0.032 12.9 0.1 0.044 12.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FHA PF00498.21 ETS75035.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 FHA domain His_Phos_2 PF00328.17 ETS75036.1 - 4e-18 65.8 0.0 5.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short_C2 PF13561.1 ETS75037.1 - 3.1e-16 59.8 0.7 5.6e-12 45.9 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS75037.1 - 1e-14 54.8 7.6 1.1e-09 38.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS75037.1 - 9.4e-05 22.1 0.7 9.4e-05 22.1 0.5 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS75037.1 - 0.00064 19.2 0.4 0.0044 16.4 0.0 2.3 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS75037.1 - 0.0045 15.7 0.0 0.0078 14.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 ETS75037.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TrkA_N PF02254.13 ETS75037.1 - 0.023 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.1 ETS75037.1 - 0.023 15.0 0.0 0.075 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 ETS75037.1 - 0.049 12.5 0.1 0.095 11.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 ETS75037.1 - 0.053 13.3 0.5 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 ETS75037.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cu_bind_like PF02298.12 ETS75038.1 - 0.022 14.5 0.4 0.06 13.1 0.3 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain SGL PF08450.7 ETS75039.1 - 0.0002 20.8 1.5 0.0017 17.7 0.6 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 ETS75039.1 - 0.044 13.5 1.0 2 8.2 0.1 2.9 3 0 0 3 3 3 0 Beta-propeller repeat HMG-CoA_red PF00368.13 ETS75040.1 - 2.9e-153 509.9 3.3 3.7e-153 509.6 2.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 ETS75040.1 - 8.9e-44 148.8 1.1 1.6e-43 148.0 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 ETS75040.1 - 7.2e-15 54.7 4.5 6.9e-14 51.5 3.1 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 ETS75040.1 - 1.3e-08 33.2 0.4 1.3e-08 33.2 0.3 1.5 2 0 0 2 2 2 1 Patched family Isochorismatase PF00857.15 ETS75041.1 - 4.5e-26 91.8 0.0 7.7e-26 91.0 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF3328 PF11807.3 ETS75044.1 - 2.4e-41 141.7 0.1 3.5e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ldl_recept_b PF00058.12 ETS75045.1 - 0.11 12.8 0.4 14 6.0 0.2 2.2 1 1 1 2 2 2 0 Low-density lipoprotein receptor repeat class B DUF309 PF03745.9 ETS75046.1 - 0.012 15.0 0.6 0.018 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Alpha_GJ PF03229.8 ETS75046.1 - 2.8 8.3 5.4 3.7 7.9 3.7 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J RAP1 PF07218.6 ETS75046.1 - 6 4.8 7.9 5.3 5.0 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1399 PF07173.7 ETS75047.1 - 8.3e-22 77.9 0.3 3.1e-15 56.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) DUF2945 PF11160.3 ETS75048.1 - 1.9e-16 59.5 0.2 1.9e-16 59.5 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2945) MIP-T3 PF10243.4 ETS75048.1 - 0.2 10.1 32.6 0.24 9.8 22.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 ETS75048.1 - 0.46 9.5 44.6 0.65 8.9 30.9 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.8 ETS75048.1 - 0.56 8.2 32.2 0.63 8.1 22.3 1.1 1 0 0 1 1 1 0 Utp14 protein Mem_trans PF03547.13 ETS75048.1 - 0.85 7.8 3.2 0.83 7.8 2.2 1.3 1 0 0 1 1 1 0 Membrane transport protein TFIIF_alpha PF05793.7 ETS75048.1 - 0.91 7.8 49.7 1.1 7.5 34.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETS75048.1 - 3.7 5.3 48.7 4.5 5.0 33.8 1.1 1 0 0 1 1 1 0 Nop14-like family Hce2 PF14856.1 ETS75049.1 - 8.5e-14 51.2 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.1 ETS75050.1 - 0.00063 19.6 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.1 ETS75051.1 - 2.2e-05 24.2 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.1 ETS75052.1 - 1e-10 41.3 0.7 1.3e-10 41.0 0.5 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GH-E PF14410.1 ETS75053.1 - 0.091 12.9 0.1 0.9 9.7 0.0 2.0 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Malic_M PF03949.10 ETS75054.1 - 1.2e-79 267.4 0.1 1.7e-79 266.9 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 ETS75054.1 - 1.2e-61 207.4 0.0 2.3e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain FliT PF05400.8 ETS75055.1 - 0.093 13.1 1.8 1.8 9.0 0.3 2.4 2 0 0 2 2 2 0 Flagellar protein FliT NUP50 PF08911.6 ETS75055.1 - 0.56 10.6 2.2 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) PglZ PF08665.7 ETS75059.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Elong_Iki1 PF10483.4 ETS75059.1 - 0.13 11.6 0.9 1.8 7.8 0.2 2.0 2 0 0 2 2 2 0 Elongator subunit Iki1 DUF678 PF05077.7 ETS75059.1 - 7.6 6.6 6.3 0.93 9.5 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF678) DUF2413 PF10310.4 ETS75061.1 - 7.5e-144 479.8 0.0 8.6e-144 479.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ribosomal_L14 PF00238.14 ETS75063.1 - 4.2e-31 107.2 0.0 4.6e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 ETS75064.1 - 2e-79 267.1 0.3 4.5e-79 265.9 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain DUF1311 PF07007.7 ETS75064.1 - 2.3 8.3 7.0 0.23 11.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) GST_N_3 PF13417.1 ETS75065.1 - 1.8e-11 44.0 0.1 1e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS75065.1 - 6.2e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS75065.1 - 2.5e-05 24.3 0.0 5.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS75065.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS75065.1 - 0.00061 19.6 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS75065.1 - 0.0042 17.5 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bac_luciferase PF00296.15 ETS75066.1 - 2.8e-64 217.1 6.6 3.7e-64 216.7 4.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase COesterase PF00135.23 ETS75067.1 - 8.9e-87 292.0 0.1 6.1e-79 266.1 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS75067.1 - 7.3e-14 51.8 0.1 1.3e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS75067.1 - 2.9e-05 23.8 0.3 5.1e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS75067.1 - 0.026 13.7 0.1 0.056 12.6 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 ETS75068.1 - 2.7e-16 59.2 0.1 4.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75068.1 - 3.1e-09 36.5 7.9 6.7e-09 35.5 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS75069.1 - 1.6e-40 138.9 26.6 1.6e-40 138.9 18.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS75069.1 - 1e-10 40.7 18.0 2e-10 39.8 12.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4191 PF13829.1 ETS75069.1 - 0.75 8.8 7.6 8.1 5.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) JAB PF01398.16 ETS75070.1 - 9.5e-35 118.7 0.0 1.8e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETS75070.1 - 7.3e-27 93.7 1.6 7.3e-27 93.7 1.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 ETS75070.1 - 8.9e-09 34.8 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ank_2 PF12796.2 ETS75072.1 - 1e-34 118.6 18.9 2e-11 44.0 0.1 5.2 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS75072.1 - 2.9e-28 97.2 11.1 1.5e-05 25.1 0.1 8.1 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 ETS75072.1 - 3.4e-28 96.0 12.8 6e-06 25.8 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 ETS75072.1 - 2.9e-25 88.1 10.5 1.6e-05 25.2 0.2 6.6 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75072.1 - 1.7e-22 77.2 6.0 0.0011 18.9 0.0 8.7 7 0 0 7 7 7 6 Ankyrin repeat NACHT PF05729.7 ETS75072.1 - 0.0027 17.3 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS75072.1 - 0.062 13.4 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF869 PF05911.6 ETS75072.1 - 0.55 8.3 3.8 11 4.1 1.0 1.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Acetyltransf_7 PF13508.1 ETS75073.1 - 2.8e-09 37.0 0.0 5.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS75073.1 - 5.5e-08 32.4 0.0 9.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 ETS75073.1 - 4.9e-06 26.4 0.0 8.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS75073.1 - 6.4e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS75073.1 - 0.0014 18.6 0.0 0.0057 16.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1330 PF07045.6 ETS75074.1 - 0.045 13.6 0.1 0.3 10.9 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) FAD-oxidase_C PF02913.14 ETS75075.1 - 5.3e-52 176.6 0.2 1e-51 175.6 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS75075.1 - 8.8e-37 125.6 0.0 2e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 ETS75076.1 - 1.2e-21 76.2 1.2 1.2e-21 76.2 0.9 2.8 3 0 0 3 3 3 1 Clr5 domain Fungal_trans PF04082.13 ETS75077.1 - 4.9e-26 91.1 0.2 9.1e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75077.1 - 0.0047 16.8 9.4 0.0092 15.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Claudin_3 PF06653.6 ETS75077.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Glyco_tranf_2_3 PF13641.1 ETS75078.1 - 1.4e-19 70.8 0.0 2.2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS75078.1 - 3.6e-08 32.8 0.1 8.6e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 ETS75078.1 - 4.7e-08 32.8 0.0 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_76 PF03663.9 ETS75080.1 - 1.4e-134 449.1 4.9 1.8e-134 448.7 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aldo_ket_red PF00248.16 ETS75081.1 - 3.7e-76 255.6 0.0 4.1e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 ETS75084.1 - 2.5e-58 194.3 4.8 2.1e-16 60.0 0.1 6.7 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75084.1 - 9.5e-52 170.3 13.4 1.7e-06 27.5 0.1 11.9 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 ETS75084.1 - 6.9e-40 131.0 9.7 9e-05 22.3 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 ETS75084.1 - 3.3e-35 119.3 12.5 1.1e-06 28.6 0.1 10.1 7 4 3 10 10 10 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS75084.1 - 1.6e-34 117.6 10.3 3e-07 30.7 0.1 9.4 4 2 5 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.7 ETS75084.1 - 1.4e-11 44.3 0.4 3.1e-11 43.2 0.3 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS75084.1 - 0.0019 18.2 1.0 0.015 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS75084.1 - 0.0092 16.1 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS75084.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 ETS75084.1 - 0.083 12.3 0.0 4.1 6.7 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain MerC PF03203.9 ETS75085.1 - 0.092 13.1 5.2 0.18 12.2 0.3 2.9 3 0 0 3 3 3 0 MerC mercury resistance protein DUF4131 PF13567.1 ETS75085.1 - 1.3 8.4 7.1 0.2 11.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Abhydrolase_6 PF12697.2 ETS75086.1 - 9.1e-13 48.6 0.0 1.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS75086.1 - 9.5e-06 25.4 0.3 4.9e-05 23.1 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF3447 PF11929.3 ETS75086.1 - 0.083 12.7 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Arf PF00025.16 ETS75086.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family CopD PF05425.8 ETS75089.1 - 0.013 15.6 0.2 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 Copper resistance protein D HEAT_2 PF13646.1 ETS75090.1 - 8.9e-19 67.5 10.0 1.5e-07 31.5 0.8 5.2 3 2 1 4 4 4 4 HEAT repeats NACHT PF05729.7 ETS75090.1 - 3.3e-15 56.1 0.3 2.1e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.1 ETS75090.1 - 2e-06 28.1 3.0 0.22 12.0 0.1 5.3 2 2 3 5 5 5 2 HEAT-like repeat HEAT PF02985.17 ETS75090.1 - 3.6e-06 26.5 1.3 0.1 12.7 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 ETS75090.1 - 5e-05 21.8 1.1 0.00036 18.9 0.3 2.1 2 0 0 2 2 2 1 Adaptin N terminal region AAA_17 PF13207.1 ETS75090.1 - 5.4e-05 23.9 0.8 0.0016 19.2 0.0 3.7 3 1 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.2 ETS75090.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS75090.1 - 0.00021 20.9 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 ETS75090.1 - 0.00034 20.7 0.0 0.0016 18.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS75090.1 - 0.00054 20.2 1.5 0.0072 16.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ETS75090.1 - 0.00086 19.3 3.1 0.0018 18.2 0.0 2.9 2 1 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.17 ETS75090.1 - 0.0018 17.1 0.0 0.0046 15.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain DNA_alkylation PF08713.6 ETS75090.1 - 0.0073 15.8 4.8 0.27 10.7 0.5 2.7 1 1 1 2 2 2 2 DNA alkylation repair enzyme Arch_ATPase PF01637.13 ETS75090.1 - 0.0098 15.6 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 ETS75090.1 - 0.013 15.2 0.0 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS75090.1 - 0.032 14.1 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 ETS75090.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 ETS75090.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 ETS75090.1 - 0.075 13.3 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 ETS75090.1 - 0.076 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 ETS75090.1 - 0.081 12.4 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vitellogenin_N PF01347.17 ETS75090.1 - 0.084 11.0 0.2 0.19 9.8 0.1 1.5 1 1 1 2 2 2 0 Lipoprotein amino terminal region ArgK PF03308.11 ETS75090.1 - 0.13 11.0 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Viral_helicase1 PF01443.13 ETS75090.1 - 0.24 10.9 0.0 0.6 9.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase F-box PF00646.28 ETS75091.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 F-box domain Kinesin PF00225.18 ETS75092.1 - 2e-115 385.0 0.0 2.8e-115 384.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 ETS75092.1 - 0.018 14.8 3.4 0.041 13.6 2.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Atg14 PF10186.4 ETS75094.1 - 4.3e-20 71.8 0.0 2.5e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3138 PF11336.3 ETS75094.1 - 0.0051 15.0 3.4 0.054 11.6 0.6 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3138) WD40 PF00400.27 ETS75095.1 - 2.2e-11 43.1 9.9 0.01 15.7 0.6 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 ETS75095.1 - 0.00065 19.5 0.7 0.0016 18.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 ETS75095.1 - 0.0061 16.3 1.0 0.0061 16.3 0.7 2.6 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF4379 PF14311.1 ETS75095.1 - 2.7 7.8 8.0 4.9 7.0 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) OrfB_Zn_ribbon PF07282.6 ETS75095.1 - 9.5 5.9 9.2 0.44 10.2 0.7 3.0 4 0 0 4 4 4 0 Putative transposase DNA-binding domain DHDPS PF00701.17 ETS75096.1 - 2.9e-43 147.5 0.0 3.3e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-C2H2 PF00096.21 ETS75098.1 - 1.7e-10 40.5 8.3 5.9e-05 23.1 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS75098.1 - 1.2e-07 31.5 5.0 0.011 16.0 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS75098.1 - 2.2e-05 24.4 1.8 0.051 13.7 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 ETS75098.1 - 0.0015 18.6 2.2 1.7 8.8 0.3 2.6 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 ETS75098.1 - 0.0023 18.0 0.7 0.93 9.7 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 ETS75098.1 - 0.089 13.1 12.8 0.1 12.9 0.1 4.0 5 0 0 5 5 5 0 Zinc-finger double domain zf-HYPF PF07503.7 ETS75098.1 - 0.099 12.0 3.8 0.21 11.0 0.3 2.7 3 0 0 3 3 3 0 HypF finger zf-C2H2_6 PF13912.1 ETS75098.1 - 0.16 11.9 0.6 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 ETS75098.1 - 0.99 9.2 5.0 4.3 7.1 0.1 3.0 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 ETS75098.1 - 2 8.7 7.8 27 5.2 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain OTT_1508_deam PF14441.1 ETS75099.1 - 5.2e-18 65.2 0.1 1.1e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 ETS75099.1 - 0.086 12.8 1.6 0.26 11.2 1.1 1.8 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases PNP_UDP_1 PF01048.15 ETS75100.1 - 1.7e-11 43.5 0.5 1.1e-10 40.9 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 ETS75100.1 - 2.9e-09 37.1 1.0 9.7e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS75100.1 - 0.013 15.6 0.1 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 ETS75100.1 - 0.031 14.5 1.8 0.084 13.1 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 ETS75100.1 - 0.035 13.9 1.1 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat Alpha-amyl_C2 PF07821.7 ETS75100.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain HET PF06985.6 ETS75102.1 - 1e-21 77.5 4.7 1.1e-18 67.7 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1206 PF06724.6 ETS75103.1 - 0.083 12.6 2.0 0.37 10.5 1.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Neuromodulin_N PF10580.4 ETS75103.1 - 0.12 12.0 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Gap junction protein N-terminal region Vanabin-2 PF11437.3 ETS75103.1 - 0.63 10.0 8.8 0.9 9.5 6.1 1.3 1 0 0 1 1 1 0 Vanadium-binding protein 2 DUF2845 PF11006.3 ETS75103.1 - 1.2 9.0 3.7 1.9 8.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) PcF PF09461.5 ETS75103.1 - 1.5 8.7 7.9 0.89 9.5 3.7 2.1 1 1 0 1 1 1 0 Phytotoxin PcF protein BSP_II PF05432.6 ETS75104.1 - 0.00047 19.5 5.0 0.00053 19.3 3.4 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 ETS75104.1 - 0.0023 15.9 10.6 0.0025 15.8 7.3 1.0 1 0 0 1 1 1 1 Nop14-like family FAM176 PF14851.1 ETS75104.1 - 0.02 14.6 2.1 0.03 13.9 1.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 ETS75104.1 - 0.02 12.9 7.1 0.021 12.8 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETS75104.1 - 0.033 13.9 8.0 0.051 13.3 5.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal HSP90 PF00183.13 ETS75104.1 - 0.048 12.0 3.4 0.052 11.9 2.4 1.1 1 0 0 1 1 1 0 Hsp90 protein Beta-APP PF03494.8 ETS75104.1 - 0.049 13.1 0.3 0.097 12.1 0.2 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Sporozoite_P67 PF05642.6 ETS75104.1 - 0.052 11.4 5.2 0.063 11.1 3.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prothymosin PF03247.9 ETS75104.1 - 0.13 12.3 27.1 0.19 11.8 18.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Herpes_gE PF02480.11 ETS75104.1 - 0.14 10.4 0.3 0.22 9.7 0.2 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E eIF-3c_N PF05470.7 ETS75104.1 - 0.15 10.1 3.5 0.16 10.0 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 ETS75104.1 - 0.38 8.7 5.9 0.41 8.6 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 ETS75104.1 - 0.43 9.0 17.8 0.55 8.6 12.4 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 ETS75104.1 - 2.2 7.4 19.5 3.1 6.9 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.6 ETS75104.1 - 2.9 7.5 7.1 4.3 6.9 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 ETS75104.1 - 5.4 6.5 18.1 8 6.0 12.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 ETS75104.1 - 6 6.3 23.3 9.4 5.7 16.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 ETS75104.1 - 6.7 6.0 13.1 9.9 5.4 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DEAD PF00270.24 ETS75106.1 - 4.1e-24 84.9 0.0 7e-23 80.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS75106.1 - 6.6e-23 80.3 0.2 1.4e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS75106.1 - 7.5e-05 22.6 0.2 0.00033 20.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS75106.1 - 0.0022 16.8 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 ETS75106.1 - 0.04 12.4 0.2 0.086 11.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ABC_tran PF00005.22 ETS75107.1 - 1.1e-48 164.9 0.2 3.8e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS75107.1 - 2.2e-27 96.2 35.4 4.8e-24 85.2 12.4 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS75107.1 - 2.5e-11 43.2 0.5 0.0013 18.0 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS75107.1 - 1.1e-10 42.0 0.0 0.0051 16.8 0.0 4.2 2 2 0 3 3 3 2 AAA domain AAA_22 PF13401.1 ETS75107.1 - 4.6e-08 33.2 2.1 0.0027 17.8 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS75107.1 - 4.9e-06 26.6 0.1 0.041 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 ETS75107.1 - 5e-05 22.3 0.8 0.0035 16.2 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF258 PF03193.11 ETS75107.1 - 0.0001 21.5 1.2 0.055 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 ETS75107.1 - 0.00012 21.9 0.3 0.58 10.1 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit cobW PF02492.14 ETS75107.1 - 0.00016 21.2 2.1 0.086 12.2 0.3 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 ETS75107.1 - 0.00033 20.1 1.3 0.039 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain Miro PF08477.8 ETS75107.1 - 0.00041 20.8 0.1 0.069 13.6 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 ETS75107.1 - 0.00063 19.4 1.5 0.078 12.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 ETS75107.1 - 0.00096 18.6 1.0 0.0035 16.8 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS75107.1 - 0.0011 19.2 0.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS75107.1 - 0.0012 19.0 0.0 0.65 10.1 0.0 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 ETS75107.1 - 0.0023 17.3 0.3 0.081 12.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 ETS75107.1 - 0.0043 16.7 1.0 0.073 12.7 0.0 2.8 3 0 0 3 3 2 1 NTPase Pox_A32 PF04665.7 ETS75107.1 - 0.0047 16.2 1.1 0.53 9.5 0.0 2.7 3 0 0 3 3 2 1 Poxvirus A32 protein NACHT PF05729.7 ETS75107.1 - 0.0052 16.4 0.1 2.3 7.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 ETS75107.1 - 0.0053 16.6 0.0 5.2 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 ETS75107.1 - 0.0057 15.3 2.0 0.024 13.2 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 ETS75107.1 - 0.0058 16.0 2.8 1.1 8.5 0.0 3.3 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.18 ETS75107.1 - 0.015 15.0 0.3 3.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 ETS75107.1 - 0.016 14.9 0.1 2.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 ETS75107.1 - 0.019 13.8 1.7 1.5 7.5 0.0 3.1 2 1 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 ETS75107.1 - 0.019 15.2 0.1 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETS75107.1 - 0.027 14.2 1.6 0.059 13.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 ETS75107.1 - 0.029 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 ETS75107.1 - 0.029 14.3 0.1 0.97 9.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 ETS75107.1 - 0.031 13.3 0.4 0.87 8.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 ETS75107.1 - 0.048 12.8 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 ETS75107.1 - 0.055 13.0 2.3 2.2 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 ETS75107.1 - 0.07 12.7 0.9 5.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PRK PF00485.13 ETS75107.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETS75107.1 - 0.26 12.1 0.2 1.1 10.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain Fungal_trans_2 PF11951.3 ETS75108.1 - 4e-18 65.1 2.7 9.1e-18 64.0 1.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Conotoxin PF02950.12 ETS75108.1 - 5 8.0 5.8 2.5 8.9 0.1 2.9 3 0 0 3 3 3 0 Conotoxin GMC_oxred_N PF00732.14 ETS75109.1 - 5.1e-52 176.8 0.0 6.3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS75109.1 - 1e-35 123.1 0.0 2e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS75109.1 - 5e-06 25.6 0.4 0.061 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 ETS75109.1 - 0.0004 19.4 0.0 0.00078 18.4 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 ETS75109.1 - 0.017 14.2 0.3 0.043 12.9 0.1 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 ETS75109.1 - 0.021 14.8 0.5 0.08 12.9 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS75109.1 - 0.027 13.3 0.2 0.049 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS75109.1 - 0.045 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 ETS75110.1 - 3.5e-07 30.4 0.0 0.0097 16.2 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS75110.1 - 5.6e-07 29.1 0.0 0.0053 16.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 ETS75110.1 - 1.1e-06 28.0 0.1 0.00052 19.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 ETS75110.1 - 3.8e-06 26.9 0.1 0.0017 18.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS75110.1 - 3.9e-05 24.0 0.0 0.31 11.6 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF445 PF04286.7 ETS75110.1 - 0.91 8.9 7.6 1.7 8.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NACHT PF05729.7 ETS75111.1 - 6.2e-06 25.9 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS75111.1 - 0.0052 16.9 0.0 0.071 13.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain Apolipoprotein PF01442.13 ETS75111.1 - 0.021 14.3 0.4 0.099 12.1 0.3 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AAA_10 PF12846.2 ETS75111.1 - 0.023 14.1 0.1 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 ETS75111.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 ETS75111.1 - 0.062 13.5 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETS75111.1 - 0.084 12.4 0.2 0.42 10.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADH_N PF08240.7 ETS75112.1 - 4.3e-31 106.8 0.6 1.6e-30 105.0 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS75112.1 - 6.1e-24 84.0 0.1 1.2e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS75112.1 - 1.9e-06 28.8 0.1 4.7e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 ETS75112.1 - 0.0032 17.8 0.0 0.068 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75112.1 - 0.0054 15.2 0.2 0.0077 14.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 ETS75112.1 - 0.039 13.5 0.4 0.078 12.5 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 ETS75112.1 - 0.042 14.4 0.1 0.12 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 ETS75112.1 - 0.066 12.5 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS75112.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 ETS75112.1 - 0.11 12.3 0.7 0.37 10.6 0.4 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydro_2_N PF02837.13 ETS75113.1 - 3.6e-12 46.1 0.0 1.2e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS75113.1 - 3.7e-11 43.4 0.6 1.1e-10 41.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 ETS75113.1 - 4.4e-05 22.5 0.2 7.5e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2236 PF09995.4 ETS75114.1 - 1.5e-54 184.8 2.5 2.3e-54 184.2 1.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) dsrm PF00035.20 ETS75115.1 - 2.3e-06 28.1 0.0 3.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif adh_short PF00106.20 ETS75116.1 - 7.1e-22 78.0 0.9 1e-21 77.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75116.1 - 8.3e-10 38.6 0.6 1.8e-09 37.5 0.4 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS75116.1 - 0.0068 15.1 0.1 0.074 11.7 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.17 ETS75117.1 - 5.1e-42 143.0 0.0 6.7e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS75117.1 - 3.6e-16 59.7 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS75117.1 - 1.3e-10 40.7 0.0 1.1e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS75117.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETS75117.1 - 0.0025 17.2 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 ETS75117.1 - 0.0057 15.8 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 ETS75117.1 - 0.0067 16.5 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS75117.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 ETS75117.1 - 0.017 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS75117.1 - 0.02 14.0 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS75117.1 - 0.034 14.1 0.1 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 ETS75117.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 ETS75117.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 ETS75117.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain 2-Hacid_dh_C PF02826.14 ETS75119.1 - 2.9e-44 150.3 0.0 2.2e-43 147.4 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS75119.1 - 3.1e-05 23.4 0.0 3.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS75119.1 - 0.032 14.0 0.2 0.082 12.7 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 ETS75122.1 - 1.4e-48 165.4 48.1 1.4e-48 165.4 33.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS75122.1 - 4.7e-26 91.1 15.4 6.5e-26 90.6 10.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS75122.1 - 6.2e-13 48.1 12.3 6.2e-13 48.1 8.5 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 ETS75122.1 - 7.8e-09 34.4 33.7 0.00013 20.4 7.5 3.2 2 1 0 2 2 2 2 MFS/sugar transport protein DUF3493 PF11998.3 ETS75123.1 - 0.11 12.4 1.7 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Esterase_phd PF10503.4 ETS75124.1 - 1.1e-21 77.1 1.2 1.6e-21 76.6 0.8 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS75124.1 - 3.8e-10 39.3 1.8 5.5e-10 38.8 1.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS75124.1 - 1.5e-06 28.0 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75124.1 - 0.00011 22.1 0.1 0.00013 21.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS75124.1 - 0.0033 16.9 0.1 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETS75124.1 - 0.0035 16.9 0.3 0.0047 16.5 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS75124.1 - 0.0045 15.7 1.5 0.0093 14.7 0.2 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.15 ETS75124.1 - 0.0078 15.7 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS75124.1 - 0.16 11.3 3.1 0.16 11.3 1.3 1.4 1 1 0 1 1 1 0 Putative esterase Sulfotransfer_3 PF13469.1 ETS75125.1 - 0.0007 20.5 0.1 0.00083 20.3 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family UPF0075 PF03702.9 ETS75126.1 - 0.049 12.5 0.1 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Peptidase_S8 PF00082.17 ETS75127.1 - 4.4e-41 140.8 18.9 6.7e-41 140.2 13.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 ETS75127.1 - 2e-17 63.5 0.1 4.1e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zip PF02535.17 ETS75128.1 - 2.4e-51 174.6 1.1 3e-51 174.3 0.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3357 PF11837.3 ETS75128.1 - 0.014 15.2 2.9 0.83 9.5 0.0 4.1 3 2 1 5 5 5 0 Domain of unknown function (DUF3357) Pkinase PF00069.20 ETS75130.1 - 1.3e-70 237.5 0.0 2.1e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75130.1 - 1.5e-32 112.6 0.0 8e-31 107.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS75130.1 - 0.00018 20.5 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS75130.1 - 0.01 15.6 1.9 0.13 11.9 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 ETS75130.1 - 0.045 13.1 0.4 0.11 11.8 0.3 1.7 1 1 0 1 1 1 0 RIO1 family Glyco_hydro_12 PF01670.11 ETS75132.1 - 7.5e-38 129.7 1.4 1.3e-37 129.0 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 SMP PF04927.7 ETS75133.1 - 2.6e-13 49.7 7.3 1.7e-09 37.5 1.0 2.1 1 1 1 2 2 2 2 Seed maturation protein zf-C2H2_jaz PF12171.3 ETS75134.1 - 5.4e-13 48.6 16.1 9.5e-06 25.6 0.3 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS75134.1 - 3.7e-12 45.9 18.1 1.8e-05 24.7 1.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 ETS75134.1 - 1.6e-11 43.6 23.3 0.026 14.8 1.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS75134.1 - 6.4e-10 38.7 27.5 0.002 18.3 1.7 5.1 5 1 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ETS75134.1 - 3.7e-07 30.1 15.0 0.022 14.8 0.6 4.1 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 ETS75134.1 - 0.00043 20.4 16.1 0.19 12.0 0.2 4.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS75134.1 - 0.011 15.6 12.7 0.021 14.7 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Ecl1 PF12855.2 ETS75134.1 - 0.014 14.6 0.4 1.1 8.6 0.1 2.7 2 1 0 2 2 2 0 Life-span regulatory factor zf-DBF PF07535.7 ETS75134.1 - 0.044 13.4 7.2 0.28 10.8 0.4 3.3 3 0 0 3 3 3 0 DBF zinc finger zf-Di19 PF05605.7 ETS75134.1 - 0.13 12.4 0.2 0.13 12.4 0.1 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 ETS75134.1 - 0.32 10.7 13.2 0.51 10.0 0.1 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C3HC4_3 PF13920.1 ETS75134.1 - 0.39 10.4 8.5 0.11 12.1 2.0 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF629 PF04780.7 ETS75134.1 - 0.39 9.1 11.2 2.2 6.7 1.6 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF629) AKAP95 PF04988.7 ETS75134.1 - 0.73 9.5 7.3 2.5 7.8 0.6 2.6 2 2 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-Sec23_Sec24 PF04810.10 ETS75134.1 - 0.98 9.0 6.2 4.9 6.8 0.2 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-RING_3 PF14369.1 ETS75134.1 - 1.7 8.7 15.7 0.26 11.3 3.7 3.7 2 2 0 2 2 2 0 zinc-finger Pkinase PF00069.20 ETS75135.1 - 2.3e-62 210.4 0.0 5.1e-62 209.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75135.1 - 6.3e-35 120.4 0.0 1.8e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS75135.1 - 4.4e-06 25.8 0.0 0.0043 16.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS75135.1 - 0.0064 16.2 0.2 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS75135.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS75135.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GWT1 PF06423.7 ETS75136.1 - 3.6e-45 153.3 1.8 3.6e-45 153.3 1.3 2.0 2 0 0 2 2 2 1 GWT1 BatA PF07584.6 ETS75136.1 - 0.15 12.2 3.6 0.48 10.6 0.4 3.3 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal Rax2 PF12768.2 ETS75139.1 - 9.4e-05 21.7 0.1 9.4e-05 21.7 0.1 1.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Mid2 PF04478.7 ETS75139.1 - 0.0019 17.6 0.3 0.0039 16.6 0.1 1.5 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor RCR PF12273.3 ETS75139.1 - 0.0037 17.8 7.0 0.0037 17.8 4.8 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Podoplanin PF05808.6 ETS75139.1 - 0.0065 16.0 2.0 0.011 15.3 1.4 1.3 1 0 0 1 1 1 1 Podoplanin IncA PF04156.9 ETS75139.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 ETS75139.1 - 0.016 13.5 0.1 0.02 13.2 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1517 PF07466.6 ETS75139.1 - 0.063 12.2 2.5 0.043 12.8 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 ETS75139.1 - 0.12 11.7 0.1 0.39 10.0 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 ETS75139.1 - 0.48 10.7 9.1 0.92 9.8 6.3 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Glyoxalase_2 PF12681.2 ETS75140.1 - 8.1e-17 61.7 0.0 9.7e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETS75140.1 - 1.2e-12 47.9 0.0 2.2e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETS75140.1 - 7.6e-08 32.3 0.1 1.3e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 ETS75140.1 - 6.7e-06 26.1 0.1 0.00045 20.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyco_transf_28 PF03033.15 ETS75141.1 - 7.8e-19 67.8 0.0 2.2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS75141.1 - 8.5e-07 27.8 0.1 1.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS75141.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FOLN PF09289.5 ETS75142.1 - 0.12 12.2 0.4 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain Sugar_tr PF00083.19 ETS75143.1 - 5.4e-93 312.0 19.9 6.3e-93 311.7 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75143.1 - 5.4e-24 84.5 36.3 6.7e-23 80.9 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS75143.1 - 0.0025 16.0 5.3 0.021 13.0 0.7 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS75144.1 - 2.5e-40 138.2 28.4 2.5e-40 138.2 19.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS75144.1 - 0.017 14.8 5.5 0.021 14.5 2.3 2.4 2 0 0 2 2 2 0 MFS_1 like family GP41 PF00517.12 ETS75144.1 - 3.6 7.0 6.6 0.3 10.6 0.3 2.2 3 0 0 3 3 3 0 Retroviral envelope protein adh_short_C2 PF13561.1 ETS75145.1 - 1.3e-34 120.0 0.0 1.7e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS75145.1 - 9.3e-30 103.7 0.1 1.4e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75145.1 - 1.4e-11 44.3 0.1 2.6e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS75145.1 - 1.3e-07 31.2 0.1 2.7e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 ETS75145.1 - 0.0081 16.5 0.2 0.69 10.3 0.0 2.2 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS75145.1 - 0.0085 16.0 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 ETS75145.1 - 0.017 14.7 0.2 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETS75145.1 - 0.03 14.7 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 ETS75145.1 - 0.063 13.2 0.1 0.096 12.6 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 ETS75145.1 - 0.33 10.7 1.7 0.65 9.8 1.0 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldedh PF00171.17 ETS75147.1 - 4.9e-149 496.5 0.1 6e-149 496.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 ETS75148.1 - 2.2e-23 83.0 1.4 2.7e-23 82.6 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS75148.1 - 2.5e-22 79.8 0.0 3.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS75148.1 - 4e-12 46.1 0.8 5.4e-12 45.7 0.5 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS75148.1 - 0.0065 16.4 0.4 0.014 15.3 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding ATP-grasp_4 PF13535.1 ETS75148.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain zf-C2H2 PF00096.21 ETS75149.1 - 5.1e-06 26.5 3.3 0.021 15.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS75149.1 - 0.00027 21.0 1.9 0.049 13.9 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS75149.1 - 0.0062 16.6 1.6 2.6 8.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Pex14_N PF04695.8 ETS75149.1 - 0.064 13.2 2.9 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-Di19 PF05605.7 ETS75149.1 - 0.11 12.6 1.0 3.4 7.8 0.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 ETS75149.1 - 0.17 11.8 3.0 3.8 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Ribosomal_60s PF00428.14 ETS75149.1 - 0.35 11.2 7.9 0.054 13.9 1.8 2.2 2 1 1 3 3 3 0 60s Acidic ribosomal protein Meth_synt_2 PF01717.13 ETS75150.1 - 1.7e-11 43.6 0.0 1.7e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS75150.1 - 0.00079 18.7 0.0 0.22 10.7 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L39 PF00832.15 ETS75151.1 - 0.064 12.7 0.4 0.12 11.8 0.3 1.4 1 0 0 1 1 1 0 Ribosomal L39 protein AhpC-TSA PF00578.16 ETS75152.1 - 1.8e-31 108.3 0.0 2.6e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS75152.1 - 5.1e-12 45.5 0.0 7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 ETS75152.1 - 6.8e-12 44.8 0.1 1.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 ETS75153.1 - 4.3e-21 74.4 3.3 5.6e-11 42.3 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS75153.1 - 1.3e-17 63.2 0.0 2.6e-08 33.4 0.0 5.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS75153.1 - 7.4e-12 44.9 4.6 1e-05 25.3 0.1 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETS75153.1 - 1.1e-10 41.2 3.1 0.0024 17.9 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 ETS75153.1 - 1.5e-10 40.4 0.0 0.00051 19.5 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 ETS75153.1 - 1.8e-07 30.6 0.2 0.00051 19.7 0.0 4.4 4 1 0 4 4 4 1 Kelch motif BTB PF00651.26 ETS75153.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain But2 PF09792.4 ETS75154.1 - 1.8e-28 99.0 0.0 6.4e-28 97.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.7 ETS75155.1 - 2e-46 157.1 0.7 3.9e-46 156.2 0.5 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 ETS75155.1 - 2.3e-20 72.6 0.2 4.7e-15 55.5 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS75155.1 - 1.2e-05 24.6 0.0 0.00026 20.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS75155.1 - 0.00037 20.3 5.7 0.5 10.1 0.0 4.0 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 ETS75155.1 - 0.00059 19.0 0.1 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arf PF00025.16 ETS75155.1 - 0.052 12.7 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC2_membrane PF01061.19 ETS75157.1 - 3.4e-39 134.1 19.1 7.2e-39 133.1 13.3 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 ETS75157.1 - 5e-26 91.6 0.0 1.1e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 ETS75157.1 - 9.4e-09 34.7 24.0 9.4e-09 34.7 16.6 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.1 ETS75157.1 - 3e-08 33.9 0.1 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain hEGF PF12661.2 ETS75157.1 - 7e-05 22.6 20.2 0.022 14.8 2.0 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 ETS75157.1 - 0.00049 19.5 0.0 0.034 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS75157.1 - 0.0061 16.6 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS75157.1 - 0.01 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETS75157.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS75157.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS75157.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 ETS75157.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 ETS75157.1 - 0.032 13.0 19.1 0.16 10.7 10.7 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_15 PF13175.1 ETS75157.1 - 0.042 12.9 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 ETS75157.1 - 0.046 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 ETS75157.1 - 0.059 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS75157.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS75157.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 ETS75157.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 ETS75157.1 - 0.28 9.8 0.0 1.2 7.7 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein EGF_2 PF07974.8 ETS75157.1 - 6.3 7.0 33.3 0.2 11.8 1.0 4.0 4 0 0 4 4 3 0 EGF-like domain Aminotran_1_2 PF00155.16 ETS75159.1 - 6e-47 160.3 0.0 7.3e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ETS75159.1 - 3.6e-06 25.5 0.0 5.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 ETS75159.1 - 3.8e-06 26.2 0.0 6.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 ETS75159.1 - 5.9e-06 25.0 0.0 7.5e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.14 ETS75159.1 - 1.7e-05 23.7 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 ETS75159.1 - 6.6e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 ETS75159.1 - 8.1e-05 21.4 0.3 0.0028 16.3 0.1 2.2 1 1 1 2 2 2 1 Allinase Asp PF00026.18 ETS75160.1 - 3e-64 217.2 7.0 2.3e-57 194.6 5.2 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 ETS75160.1 - 1.5e-07 31.8 2.8 0.0022 18.4 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 ETS75160.1 - 0.0061 16.5 1.2 0.014 15.3 0.6 1.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 ETS75160.1 - 0.11 12.3 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease GST_C PF00043.20 ETS75161.1 - 5.8e-07 29.4 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS75161.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS75161.1 - 2.6e-05 24.3 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS75161.1 - 9e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS75161.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS75161.1 - 0.04 14.3 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DAO PF01266.19 ETS75162.1 - 7.2e-54 183.0 0.0 8.2e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS75162.1 - 0.023 14.4 0.1 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS75162.1 - 0.025 14.4 0.1 2.5 7.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 ETS75163.1 - 3.7e-10 39.0 30.2 3.7e-10 39.0 20.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS75163.1 - 2.2e-08 33.7 2.5 9.2e-08 31.7 1.7 2.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 ETS75163.1 - 5.4e-08 31.8 8.0 5.4e-08 31.8 5.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Myc_N PF01056.13 ETS75165.1 - 0.028 13.6 2.7 0.03 13.4 1.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PqqD PF05402.7 ETS75165.1 - 0.08 12.9 1.3 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Pox_RNA_Pol_19 PF05320.7 ETS75165.1 - 7.5 6.2 7.3 1.1 9.0 1.9 1.7 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit OB_NTP_bind PF07717.11 ETS75167.1 - 1.3e-13 50.7 0.0 3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS75167.1 - 4.4e-12 45.9 0.0 8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS75167.1 - 7.7e-09 35.2 0.1 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS75168.1 - 1.9e-06 28.0 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 ETS75168.1 - 2.1e-06 27.3 0.1 3.7e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS75168.1 - 8.4e-05 22.4 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 ETS75168.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Fungal_trans PF04082.13 ETS75171.1 - 2e-14 53.1 0.0 3.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75171.1 - 1.1e-06 28.3 11.5 2.2e-06 27.4 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.13 ETS75172.1 - 9.9e-19 67.7 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 ETS75172.1 - 0.05 13.1 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Period_C PF12114.3 ETS75173.1 - 7.5 6.1 7.1 9.4 5.7 4.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Fungal_trans PF04082.13 ETS75174.1 - 5.6e-10 38.5 0.1 1.3e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75174.1 - 5.2e-07 29.4 9.5 1e-06 28.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mso1_C PF14477.1 ETS75174.1 - 0.043 14.1 2.7 7.4 6.9 0.5 2.9 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 DUF59 PF01883.14 ETS75175.1 - 1.1e-06 28.5 0.0 2.8e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 ETS75176.1 - 1.2e-41 142.2 0.0 1.7e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETS75176.1 - 1.6e-26 92.2 0.0 4.6e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETS75176.1 - 3.2e-17 62.1 0.0 8.4e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS75176.1 - 5.2e-08 32.8 0.4 1.8e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETS75176.1 - 3.5e-07 29.9 0.1 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 ETS75176.1 - 0.00011 22.1 0.1 0.0002 21.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS75176.1 - 0.018 15.5 0.1 0.065 13.7 0.1 2.1 1 0 0 1 1 1 0 Miro-like protein Thiolase_N PF00108.18 ETS75177.1 - 9.9e-98 326.3 1.4 1.5e-97 325.7 1.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS75177.1 - 8.6e-44 147.9 0.5 8.6e-44 147.9 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETS75177.1 - 3.6e-05 23.3 0.4 3.6e-05 23.3 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 ETS75177.1 - 0.21 11.2 3.5 0.55 9.9 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 ETS75178.1 - 9e-51 172.8 0.0 2.4e-50 171.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 PAH PF02671.16 ETS75178.1 - 6e-48 160.2 2.8 1.2e-17 63.2 0.5 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 ETS75178.1 - 2.8e-38 129.7 1.0 4.9e-38 128.9 0.0 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Glyco_hydro_43 PF04616.9 ETS75179.1 - 1.8e-47 161.7 8.2 2.1e-47 161.6 5.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Dus PF01207.12 ETS75180.1 - 6.3e-41 140.2 0.0 1.4e-30 106.2 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 ETS75180.1 - 0.24 11.1 12.2 2.1 8.0 0.7 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_3 PF13415.1 ETS75181.1 - 3.6e-47 157.5 22.0 5.4e-10 39.1 0.1 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS75181.1 - 4.3e-46 154.4 18.7 9.1e-10 38.1 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 ETS75181.1 - 8.1e-43 143.7 15.6 1.4e-08 34.1 1.3 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 ETS75181.1 - 7.3e-42 140.7 17.1 1.2e-07 31.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 ETS75181.1 - 3.8e-37 124.9 17.1 3.5e-07 30.1 0.2 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 ETS75181.1 - 1.6e-34 116.3 16.1 5.8e-08 32.2 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Macoilin PF09726.4 ETS75181.1 - 0.065 11.5 0.3 0.066 11.5 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PQQ_3 PF13570.1 ETS75181.1 - 0.95 9.8 17.4 7.8 6.9 0.2 5.6 6 0 0 6 6 6 0 PQQ-like domain E1-E2_ATPase PF00122.15 ETS75183.1 - 2.3e-55 187.1 0.2 4.3e-55 186.2 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 ETS75183.1 - 7.9e-49 163.6 0.2 2.8e-12 46.6 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 ETS75183.1 - 3.2e-48 164.9 1.2 7.9e-48 163.7 0.8 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS75183.1 - 1.5e-14 54.6 0.0 3.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS75183.1 - 1.9e-06 27.6 0.9 7e-05 22.5 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PCI PF01399.22 ETS75184.1 - 1.5e-09 38.1 0.1 2.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 ETS75185.1 - 8.3e-12 45.2 0.0 1.5e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain O-antigen_lig PF13425.1 ETS75185.1 - 2.2 8.2 8.2 4.3 7.3 5.7 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein Ribosomal_L31e PF01198.14 ETS75186.1 - 1.7e-38 130.1 3.3 2.2e-38 129.8 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e M20_dimer PF07687.9 ETS75186.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 1 0 1 1 1 1 Peptidase dimerisation domain SBDS_C PF09377.5 ETS75186.1 - 0.024 14.3 0.3 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 SBDS protein C-terminal domain UQ_con PF00179.21 ETS75187.1 - 1.9e-48 163.4 0.0 2.4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS75187.1 - 5.3e-05 22.9 0.0 7.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS75187.1 - 0.0014 18.5 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETS75187.1 - 0.0039 16.8 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 ETS75188.1 - 3.7e-62 209.8 0.0 5.4e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75188.1 - 1.3e-29 103.0 0.0 2.9e-29 101.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS75188.1 - 8.5e-07 28.2 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS75188.1 - 0.0015 18.3 0.0 0.38 10.4 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 ETS75188.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETS75188.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PIP49_C PF12260.3 ETS75188.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 TFR_dimer PF04253.10 ETS75189.1 - 4.2e-21 74.8 0.0 7.2e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS75189.1 - 2.3e-16 60.0 0.0 4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS75189.1 - 7.1e-08 32.0 0.2 3e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 PA domain TPR_10 PF13374.1 ETS75190.1 - 4.5e-51 169.3 20.6 5.4e-09 35.6 0.0 8.3 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETS75190.1 - 2.3e-44 149.2 20.1 5.2e-13 48.7 0.3 5.1 1 1 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS75190.1 - 1.4e-12 47.9 7.4 0.0082 16.7 0.6 5.2 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETS75190.1 - 2.9e-11 42.2 23.7 0.085 12.6 0.2 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS75190.1 - 5.9e-11 42.3 19.0 0.0011 19.0 1.9 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 ETS75190.1 - 7.9e-11 41.4 9.4 0.0025 17.4 0.0 5.1 3 1 1 4 4 4 4 TPR repeat NB-ARC PF00931.17 ETS75190.1 - 3.5e-09 35.9 0.0 8.3e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 ETS75190.1 - 6.3e-09 35.0 17.4 0.017 15.0 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 ETS75190.1 - 4.1e-07 29.2 0.4 3.2e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_4 PF07721.9 ETS75190.1 - 8.6e-07 28.7 10.2 15 6.3 0.0 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS75190.1 - 9.7e-07 28.1 10.4 0.35 10.5 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS75190.1 - 1.8e-05 24.9 10.1 0.82 10.0 0.0 5.7 3 2 2 6 6 5 3 Tetratricopeptide repeat NACHT PF05729.7 ETS75190.1 - 0.00076 19.1 0.1 0.015 15.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS75190.1 - 0.0011 19.0 0.2 0.0087 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF2087 PF09860.4 ETS75190.1 - 0.0012 18.5 1.0 8.4 6.2 0.0 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) TPR_3 PF07720.7 ETS75190.1 - 0.0028 17.4 10.5 23 4.9 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.15 ETS75190.1 - 0.0068 16.3 0.0 52 4.1 0.0 5.6 6 0 0 6 6 5 0 PPR repeat TPR_17 PF13431.1 ETS75190.1 - 0.026 14.7 3.1 14 6.2 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF1925 PF09094.6 ETS75190.1 - 0.093 12.7 18.3 4.2 7.4 0.0 5.9 2 1 4 6 6 6 0 Domain of unknown function (DUF1925) TPR_14 PF13428.1 ETS75190.1 - 0.12 13.0 16.4 11 6.9 0.6 7.3 4 2 4 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS75190.1 - 0.13 12.1 4.8 3.2 7.6 0.0 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 ETS75190.1 - 1.2 9.3 21.8 2 8.6 0.1 5.6 1 1 5 6 6 6 0 Bacterial transcriptional activator domain F-box-like PF12937.2 ETS75192.1 - 4.6e-10 39.0 3.3 9.8e-10 38.0 2.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS75192.1 - 9.8e-10 37.8 5.0 2.3e-09 36.6 3.5 1.7 1 0 0 1 1 1 1 F-box domain SprT-like PF10263.4 ETS75193.1 - 4.7e-10 39.3 0.0 8.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M50 PF02163.17 ETS75193.1 - 0.034 13.1 0.2 0.053 12.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M50 DFF40 PF09230.5 ETS75194.1 - 0.0034 16.7 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa SprT-like PF10263.4 ETS75194.1 - 0.0068 16.0 0.2 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 SprT-like family DIOX_N PF14226.1 ETS75195.1 - 1.5e-25 89.9 0.0 3.1e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS75195.1 - 4.8e-15 55.6 0.0 9.7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS75196.1 - 1.3e-17 64.4 0.0 2.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS75196.1 - 8.5e-13 48.4 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS75197.1 - 4.9e-26 91.2 25.5 9.7e-26 90.2 17.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 ETS75197.1 - 9.2 6.4 9.3 1 9.4 0.1 3.3 3 0 0 3 3 3 0 2TM domain DUF1664 PF07889.7 ETS75199.1 - 0.78 9.5 9.5 8.8 6.1 0.8 4.3 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 ETS75199.1 - 0.96 8.5 8.5 1 8.4 0.1 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 ETS75199.1 - 2.3 8.1 10.4 96 2.9 0.0 5.7 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) RRF_GI PF12614.3 ETS75199.1 - 5.3 6.8 9.1 1.3 8.8 0.5 3.7 2 2 0 3 3 3 0 Ribosome recycling factor WD40 PF00400.27 ETS75200.1 - 1.5e-09 37.3 10.3 0.00075 19.2 0.0 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS75200.1 - 0.00029 20.3 0.4 0.0015 18.0 0.0 2.1 2 1 0 2 2 2 1 PQQ-like domain NAPRTase PF04095.11 ETS75201.1 - 6.6e-52 176.2 0.0 9.8e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family GIT_SHD PF08518.6 ETS75202.1 - 5.3e-21 73.6 7.4 5.5e-13 48.0 2.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 ETS75202.1 - 0.0041 16.2 21.6 0.0041 16.2 15.0 2.3 1 1 1 2 2 2 1 Autophagy protein Apg6 DUF1843 PF08898.5 ETS75202.1 - 0.022 14.7 0.2 0.022 14.7 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) AAA_13 PF13166.1 ETS75202.1 - 0.94 7.8 25.1 1.9 6.8 17.4 1.4 1 0 0 1 1 1 0 AAA domain Ssu72 PF04722.8 ETS75203.1 - 1.6e-85 285.3 0.0 1.9e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 ETS75204.1 - 8.4e-09 34.6 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS75204.1 - 1.6e-08 33.9 0.1 3.7e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS75204.1 - 6.3e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MARVEL PF01284.18 ETS75205.1 - 5.1e-06 26.3 23.7 7.5e-06 25.8 16.0 1.5 1 1 1 2 2 2 1 Membrane-associating domain 2TM PF13239.1 ETS75205.1 - 5.6 7.1 9.5 7.7 6.6 5.6 1.9 2 0 0 2 2 2 0 2TM domain IBR PF01485.16 ETS75206.1 - 0.00067 19.4 23.5 0.03 14.2 7.0 2.9 2 1 1 3 3 3 2 IBR domain Nop14 PF04147.7 ETS75206.1 - 0.0025 15.8 12.9 0.0039 15.2 8.9 1.2 1 0 0 1 1 1 1 Nop14-like family Atrophin-1 PF03154.10 ETS75206.1 - 0.038 12.1 10.1 0.057 11.5 7.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF164 PF02591.10 ETS75206.1 - 0.067 13.0 2.3 0.27 11.0 0.4 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain SAPS PF04499.10 ETS75206.1 - 0.098 11.2 0.5 0.14 10.7 0.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 ETS75206.1 - 0.11 10.5 9.1 0.16 9.9 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 ETS75206.1 - 0.14 11.6 12.2 0.27 10.7 8.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 ETS75206.1 - 0.61 7.7 7.3 0.11 10.2 2.6 1.4 2 0 0 2 2 2 0 Ycf1 zf-RING_5 PF14634.1 ETS75206.1 - 0.75 9.5 24.8 0.12 12.1 8.8 2.7 2 1 1 3 3 3 0 zinc-RING finger domain C1_4 PF07975.7 ETS75206.1 - 1.1 9.3 22.2 2.6 8.1 4.2 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain BTV_NS2 PF04514.7 ETS75206.1 - 1.4 7.7 12.3 2.8 6.7 8.5 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pox_Ag35 PF03286.9 ETS75206.1 - 1.5 8.3 17.6 3 7.3 12.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.1 ETS75206.1 - 3.9 7.4 10.5 10 6.1 7.3 1.6 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 ETS75206.1 - 5.1 5.4 16.0 8.7 4.6 11.1 1.2 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 ETS75206.1 - 5.2 5.8 14.2 11 4.6 9.8 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3395 PF11875.3 ETS75207.1 - 4.6e-24 84.7 0.0 6.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 ETS75207.1 - 1.5e-07 31.0 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 ETS75208.1 - 0.00039 19.3 0.2 0.00048 19.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_1 PF00175.16 ETS75210.1 - 1.9e-29 102.3 0.0 3.3e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS75210.1 - 1.3e-20 73.3 0.0 2.5e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS75210.1 - 9.5e-09 35.3 0.0 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS75210.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PAF-AH_p_II PF03403.8 ETS75212.1 - 1.5e-56 191.3 0.0 6.5e-54 182.6 0.0 2.3 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 ETS75212.1 - 1.9e-13 50.4 0.1 5.4e-13 48.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75212.1 - 8.9e-12 45.3 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS75212.1 - 3.1e-07 29.5 0.0 4.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS75212.1 - 2e-05 23.5 0.0 0.00051 18.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 ETS75212.1 - 0.0046 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 ETS75212.1 - 0.0059 15.9 0.0 0.19 10.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETS75212.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SnoaL_4 PF13577.1 ETS75213.1 - 3.8e-12 46.2 0.0 4.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.1 ETS75214.1 - 5.8e-12 45.9 0.0 8.6e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 ETS75214.1 - 4.1e-05 22.9 0.0 0.00035 19.8 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Methyltransf_16 PF10294.4 ETS75215.1 - 1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS75215.1 - 9.8e-08 32.5 0.1 2.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS75215.1 - 9.3e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS75215.1 - 4.8e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS75215.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS75215.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS75215.1 - 0.0042 17.0 0.3 0.0078 16.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 ETS75215.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_11 PF08241.7 ETS75215.1 - 0.02 15.3 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETS75215.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF155 PF02582.9 ETS75216.1 - 1.2e-58 197.8 0.2 2.2e-58 197.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GFO_IDH_MocA_C PF02894.12 ETS75217.1 - 6.9e-18 64.5 0.4 2.8e-17 62.5 0.2 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 ETS75217.1 - 1e-15 58.2 0.0 2.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 ETS75218.1 - 1.8e-32 112.4 29.4 1.8e-32 112.4 20.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 ETS75218.1 - 0.17 11.8 2.9 3.1 7.8 0.0 3.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.17 ETS75220.1 - 1.3e-61 208.5 0.0 1.7e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xpo1 PF08389.7 ETS75220.1 - 0.032 14.1 0.1 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Exportin 1-like protein FAD_binding_3 PF01494.14 ETS75221.1 - 2.3e-10 40.0 3.1 5e-09 35.6 1.7 2.8 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 ETS75221.1 - 0.0084 16.4 0.2 0.024 15.0 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS75221.1 - 0.0092 14.9 1.3 1.2 7.9 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75221.1 - 0.021 14.8 0.1 0.058 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_S3 PF00944.14 ETS75222.1 - 0.034 13.5 0.1 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphavirus core protein AMP-binding PF00501.23 ETS75223.1 - 1.6e-60 204.6 0.0 2.4e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 ETS75223.1 - 4.1e-07 29.1 0.1 6.8e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 ETS75223.1 - 0.00045 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site BAR_3_WASP_bdg PF10456.4 ETS75224.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DAO PF01266.19 ETS75225.1 - 5.7e-52 176.8 0.0 7.1e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75225.1 - 0.00022 21.1 0.5 0.00064 19.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS75225.1 - 0.0013 18.8 0.0 0.33 10.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS75225.1 - 0.043 12.8 0.0 0.072 12.1 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 ETS75226.1 - 3.9e-27 94.9 34.1 3.3e-24 85.2 6.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5 PF06946.6 ETS75226.1 - 0.17 12.0 2.9 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 Phage holin Fungal_trans_2 PF11951.3 ETS75227.1 - 1.3e-08 33.8 0.0 2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3483 PF11982.3 ETS75227.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF1254 PF06863.7 ETS75230.1 - 7.9e-24 83.9 2.8 1.9e-23 82.7 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.6 ETS75230.1 - 4.8e-17 62.3 1.9 5.7e-16 58.8 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) tRNA-synt_1b PF00579.20 ETS75232.1 - 1e-71 241.4 0.0 1.4e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4110 PF13422.1 ETS75232.1 - 0.012 15.3 0.2 0.038 13.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CybS PF05328.7 ETS75233.1 - 7.9e-47 158.2 0.0 1.4e-46 157.3 0.0 1.4 2 0 0 2 2 2 1 CybS Sdh_cyt PF01127.17 ETS75233.1 - 0.06 13.1 0.4 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_23 PF13489.1 ETS75234.1 - 2.9e-09 36.8 0.0 5.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS75234.1 - 0.0001 22.8 0.1 0.0023 18.5 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS75234.1 - 0.00045 20.6 0.0 0.002 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS75234.1 - 0.00057 19.5 0.1 0.013 15.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75234.1 - 0.00079 19.8 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_18 PF00704.23 ETS75235.1 - 3.4e-74 250.3 0.0 3.9e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.7 ETS75236.1 - 3.2e-101 338.8 0.0 5.9e-101 338.0 0.0 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 ETS75236.1 - 6.1e-08 31.9 3.6 1.3e-07 30.8 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec15 PF04091.7 ETS75236.1 - 0.00047 19.5 1.0 0.0022 17.3 0.1 2.1 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Zw10 PF06248.8 ETS75236.1 - 0.0028 15.9 2.3 0.0074 14.4 1.6 1.6 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.6 ETS75236.1 - 0.0055 15.3 0.9 0.011 14.4 0.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.4 ETS75236.1 - 0.018 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Ecl1 PF12855.2 ETS75237.1 - 0.00034 19.8 0.3 0.00065 18.9 0.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF2256 PF10013.4 ETS75237.1 - 0.082 12.6 3.4 0.3 10.8 2.3 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_2 PF12674.2 ETS75237.1 - 0.11 12.8 0.2 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain FhuF_C PF11575.3 ETS75237.1 - 7 6.3 8.8 0.61 9.7 2.0 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain NPR2 PF06218.6 ETS75239.1 - 2.2e-122 408.8 0.0 3e-122 408.4 0.0 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 NAD_binding_10 PF13460.1 ETS75240.1 - 7e-17 62.0 0.0 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS75240.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS75240.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 ETS75240.1 - 0.048 12.9 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 ETS75241.1 - 2.2e-24 86.2 0.1 3.4e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS75241.1 - 1.3e-15 57.8 0.0 2.4e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS75241.1 - 5.4e-10 39.2 0.1 8.7e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 ETS75241.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.13 ETS75242.1 - 7.6e-22 77.4 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75242.1 - 4.1e-05 23.4 11.6 7e-05 22.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 ETS75243.1 - 5.6e-23 82.0 0.0 1.3e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS75243.1 - 2.1e-14 52.6 0.1 1.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS75243.1 - 1.9e-09 37.4 0.0 4.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS75243.1 - 2.6e-07 29.9 0.0 0.0027 16.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS75243.1 - 5.3e-05 23.0 0.1 0.00027 20.7 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 ETS75243.1 - 0.01 14.7 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Acyl-CoA_dh_N PF02771.11 ETS75245.1 - 4.7e-06 27.1 0.0 6.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3439 PF11921.3 ETS75245.1 - 0.024 14.3 2.2 0.033 13.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Acyl-CoA_dh_1 PF00441.19 ETS75246.1 - 1.8e-23 83.3 0.4 2.6e-23 82.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS75246.1 - 1e-07 31.3 0.0 2.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS75246.1 - 7.1e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS75246.1 - 0.001 19.6 0.5 0.0045 17.5 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Aldedh PF00171.17 ETS75247.1 - 1.1e-158 528.4 0.0 1.2e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS75247.1 - 0.00023 20.0 0.0 0.00052 18.8 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS75247.1 - 0.0075 15.5 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) adh_short PF00106.20 ETS75248.1 - 9.7e-26 90.6 0.8 1.2e-25 90.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS75248.1 - 2.7e-23 82.9 0.0 3.4e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS75248.1 - 6.2e-10 39.0 0.1 8.2e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.23 ETS75249.1 - 6.6e-87 291.5 0.0 8.4e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS75249.1 - 8.9e-08 32.9 0.2 1.9e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_3 PF13738.1 ETS75250.1 - 6.4e-23 81.8 0.0 1.5e-21 77.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS75250.1 - 5.8e-12 44.5 0.0 1.2e-08 33.6 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS75250.1 - 3.6e-10 39.7 0.0 8.6e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS75250.1 - 3.1e-05 23.8 0.0 0.00022 21.0 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS75250.1 - 0.00056 18.9 0.0 0.15 10.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS75250.1 - 0.0099 14.8 0.0 0.22 10.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS75250.1 - 0.013 14.5 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DUF4339 PF14237.1 ETS75250.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) DUF2890 PF11081.3 ETS75251.1 - 0.038 14.0 0.6 0.039 14.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Helicase_C PF00271.26 ETS75253.1 - 3.2e-10 39.7 0.2 7.3e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 ETS75253.1 - 2e-08 34.1 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS75253.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 ETS75253.1 - 1.7e-05 24.3 1.9 3.5e-05 23.3 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS75253.1 - 0.044 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PALP PF00291.20 ETS75256.1 - 3.8e-33 115.0 0.1 4.3e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 ETS75256.1 - 0.0052 15.7 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 LytB protein Pyr_redox_2 PF07992.9 ETS75259.1 - 1.5e-25 90.2 4.6 8.1e-25 87.8 3.2 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS75259.1 - 2.3e-18 66.3 0.9 2.3e-16 59.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS75259.1 - 8.1e-12 45.6 0.5 4.8e-06 26.7 0.0 3.1 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS75259.1 - 2.7e-08 33.2 1.5 9e-05 21.6 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.19 ETS75259.1 - 1.3e-06 27.5 5.5 0.042 12.7 0.0 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 ETS75259.1 - 3.5e-06 27.2 0.1 0.00086 19.5 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 ETS75259.1 - 5.2e-05 22.5 0.5 0.071 12.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75259.1 - 7.7e-05 22.6 0.2 0.026 14.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS75259.1 - 0.00012 21.2 0.7 0.00079 18.5 0.0 2.3 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.1 ETS75259.1 - 0.00022 20.2 0.4 0.33 9.8 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 ETS75259.1 - 0.0015 17.4 6.0 0.2 10.4 0.4 3.3 2 1 0 3 3 3 2 FAD binding domain GIDA PF01134.17 ETS75259.1 - 0.0029 16.5 5.9 0.49 9.1 0.3 4.1 3 2 1 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS75259.1 - 0.0043 17.1 0.1 4.5 7.3 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 ETS75259.1 - 0.015 15.0 0.3 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS75259.1 - 0.03 12.9 0.1 0.39 9.2 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 ETS75259.1 - 0.03 12.7 1.0 1.7 7.0 0.2 3.1 2 1 1 3 3 3 0 HI0933-like protein Abhydrolase_3 PF07859.8 ETS75260.1 - 2.1e-51 174.5 0.0 2.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS75260.1 - 3.6e-11 42.4 0.6 9.1e-11 41.1 0.4 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS75260.1 - 1.5e-06 27.5 0.0 4.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS75260.1 - 2.4e-05 24.1 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS75260.1 - 5.8e-05 21.8 0.0 7.5e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase PF00756.15 ETS75260.1 - 0.0096 15.3 0.4 0.5 9.7 0.2 2.3 1 1 0 1 1 1 1 Putative esterase FAD_binding_3 PF01494.14 ETS75261.1 - 4.6e-20 71.9 0.0 9.6e-20 70.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS75261.1 - 1.9e-07 31.3 0.0 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS75261.1 - 1.1e-05 25.3 0.1 2.6e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS75261.1 - 7.2e-05 21.8 0.0 0.00017 20.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS75261.1 - 0.002 18.0 0.0 0.0071 16.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75261.1 - 0.0034 15.9 0.0 0.0058 15.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 ETS75261.1 - 0.0046 15.8 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.5 ETS75261.1 - 0.0079 15.0 0.0 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase AlaDh_PNT_C PF01262.16 ETS75261.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 ETS75261.1 - 0.033 13.2 0.0 0.085 11.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 ETS75261.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 ETS75262.1 - 1.5e-43 148.7 0.0 1.9e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 ETS75262.1 - 0.00016 21.4 3.6 0.00016 21.4 2.5 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.9 ETS75263.1 - 5.4e-55 184.9 11.8 6.1e-55 184.8 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 ETS75264.1 - 4.7e-34 115.0 1.0 4.9e-09 35.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS75264.1 - 0.0009 19.0 2.4 1.4 8.6 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS75264.1 - 0.0034 15.5 0.0 1.4 6.9 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 ETS75264.1 - 0.4 9.4 6.8 0.21 10.3 0.1 3.1 2 1 0 4 4 4 0 Coatomer WD associated region GMC_oxred_N PF00732.14 ETS75265.1 - 2.4e-63 214.0 0.0 4.4e-63 213.1 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS75265.1 - 3.8e-33 114.8 0.0 6.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS75265.1 - 0.00027 19.9 0.1 0.00041 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS75265.1 - 0.022 13.5 0.2 1.7 7.3 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 ETS75265.1 - 0.05 12.5 0.1 2.4 6.9 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase CBM_1 PF00734.13 ETS75266.1 - 2e-12 46.5 11.3 2e-12 46.5 7.9 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2793 PF10983.3 ETS75266.1 - 0.038 13.8 0.1 0.22 11.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2793) MARVEL PF01284.18 ETS75268.1 - 0.0023 17.7 19.9 0.0033 17.2 13.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 ETS75268.1 - 0.029 14.0 19.9 1.1 8.9 10.5 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4293 PF14126.1 ETS75268.1 - 2.8 7.8 7.7 0.28 11.1 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4018 PF13210.1 ETS75268.1 - 3 7.1 14.0 0.092 12.1 5.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Microtub_assoc PF07989.6 ETS75269.1 - 8.5e-18 63.9 8.0 8.5e-18 63.9 5.5 7.5 7 2 3 11 11 11 1 Microtubule associated Mto2_bdg PF12808.2 ETS75269.1 - 1.1e-09 38.1 9.7 1.1e-09 38.1 6.7 11.3 13 1 0 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 ETS75269.1 - 0.0018 17.5 2.1 0.0018 17.5 1.5 5.6 4 2 2 6 6 6 4 Reovirus sigma C capsid protein Shugoshin_N PF07558.6 ETS75269.1 - 0.047 13.3 18.6 12 5.7 0.2 7.6 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region FAD_binding_3 PF01494.14 ETS75270.1 - 3.3e-17 62.5 0.2 1.6e-11 43.9 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS75270.1 - 1.9e-05 24.5 0.1 4.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS75270.1 - 0.00032 20.8 0.2 0.035 14.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS75270.1 - 0.001 18.0 0.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS75270.1 - 0.003 17.9 0.2 0.22 11.9 0.0 3.0 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS75270.1 - 0.006 15.5 0.1 0.087 11.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS75270.1 - 0.014 15.1 0.7 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS75270.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PBP PF01161.15 ETS75270.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.9 ETS75270.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75270.1 - 0.18 10.2 0.0 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein PAT1 PF09770.4 ETS75271.1 - 0.19 9.9 17.7 0.25 9.5 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF755 PF05501.6 ETS75271.1 - 1.3 9.0 14.8 2 8.4 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Rick_17kDa_Anti PF05433.10 ETS75271.1 - 2 8.1 28.9 0.06 13.0 15.2 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 ETS75271.1 - 2.2 7.9 16.4 0.022 14.4 5.4 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Acetyltransf_2 PF00797.12 ETS75272.1 - 1e-42 146.3 0.1 5.8e-37 127.5 0.0 2.8 1 1 1 2 2 2 2 N-acetyltransferase RNase_T PF00929.19 ETS75273.1 - 9.5e-17 61.7 0.0 1.5e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 ETS75273.1 - 0.00092 18.7 0.8 0.0033 16.9 0.0 2.1 3 0 0 3 3 3 1 3'-5' exonuclease KAR9 PF08580.5 ETS75274.1 - 0.0075 14.5 21.1 0.16 10.1 11.3 2.1 2 0 0 2 2 2 2 Yeast cortical protein KAR9 Fzo_mitofusin PF04799.8 ETS75274.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region GatB_N PF02934.10 ETS75275.1 - 1.1e-103 346.1 0.0 1.4e-103 345.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 ETS75275.1 - 3.2e-10 39.8 0.0 6.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 GatB domain FA_desaturase PF00487.19 ETS75277.1 - 6.4e-16 58.5 10.3 6.4e-16 58.5 7.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 ETS75277.1 - 1.1e-14 53.9 0.0 3.1e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyoxalase_3 PF13468.1 ETS75278.1 - 3.6e-18 66.0 0.0 4.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain RNase_H PF00075.19 ETS75279.1 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.13 ETS75279.1 - 8.4e-08 31.9 7.6 2.2e-07 30.5 5.3 1.8 1 0 0 1 1 1 1 MYND finger RVT_3 PF13456.1 ETS75279.1 - 0.0017 18.1 0.0 0.45 10.3 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase-like zf-Mss51 PF13824.1 ETS75279.1 - 0.21 11.4 7.2 0.4 10.5 3.0 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_2 PF02230.11 ETS75280.1 - 6e-22 78.1 0.2 1.2e-20 73.9 0.1 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETS75280.1 - 6.8e-07 29.1 0.0 3.6e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75280.1 - 5.4e-06 26.4 0.0 0.01 15.7 0.0 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS75280.1 - 9.1e-06 25.0 0.0 2.9e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 ETS75280.1 - 0.00011 21.5 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase DUF2920 PF11144.3 ETS75280.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DnaJ PF00226.26 ETS75281.1 - 2.1e-08 33.7 0.9 2.1e-08 33.7 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain DEAD PF00270.24 ETS75282.1 - 6.1e-42 142.9 0.0 8.5e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS75282.1 - 2e-23 82.0 0.1 3.9e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS75282.1 - 0.0026 17.6 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit End3 PF12761.2 ETS75282.1 - 0.1 12.2 0.3 0.61 9.6 0.2 2.0 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DSPc PF00782.15 ETS75283.1 - 5.2e-29 100.4 0.0 6.2e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETS75283.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 ETS75283.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 ETS75283.1 - 0.061 12.6 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase tRNA_m1G_MT PF01746.16 ETS75286.1 - 7.5e-32 110.4 0.0 6.3e-23 81.3 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase CAF-1_p150 PF11600.3 ETS75286.1 - 0.88 8.9 29.3 1.6 8.0 20.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MutS_V PF00488.16 ETS75287.1 - 1.7e-97 325.4 0.1 2.5e-97 324.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS75287.1 - 3.1e-40 138.1 1.1 8.2e-40 136.7 0.7 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 ETS75287.1 - 1.9e-24 86.2 0.1 6.9e-24 84.4 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 ETS75287.1 - 6.3e-19 67.9 2.5 1.4e-18 66.8 0.5 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 ETS75287.1 - 5e-18 65.1 0.0 2.5e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 MutS domain I AAA_22 PF13401.1 ETS75287.1 - 0.081 13.0 0.1 1 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain PAN_1 PF00024.21 ETS75288.1 - 0.00018 21.2 12.3 0.34 10.6 0.6 3.8 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 ETS75288.1 - 0.0007 19.2 20.8 0.048 13.3 0.6 3.8 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.6 ETS75288.1 - 0.0072 16.1 0.7 0.0072 16.1 0.5 3.8 3 1 1 4 4 4 2 PAN-like domain PAN_3 PF08277.7 ETS75288.1 - 0.43 10.2 6.8 2.8 7.6 0.1 3.0 3 0 0 3 3 3 0 PAN-like domain adh_short PF00106.20 ETS75289.1 - 8.4e-12 45.3 0.0 1e-10 41.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase FMN_red PF03358.10 ETS75292.1 - 2.6e-12 46.4 0.0 4.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETS75292.1 - 8.6e-07 28.6 0.0 1.5e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold UDPGT PF00201.13 ETS75293.1 - 2e-06 26.6 0.0 2.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 ETS75293.1 - 0.0079 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain AAA_35 PF14516.1 ETS75293.1 - 0.034 12.7 0.0 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MFS_1 PF07690.11 ETS75294.1 - 3e-32 111.7 27.6 3e-32 111.7 19.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS75294.1 - 2.6e-11 42.7 13.8 2.6e-11 42.7 9.6 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF3169 PF11368.3 ETS75294.1 - 0.019 14.1 4.9 1.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CorA PF01544.13 ETS75294.1 - 0.42 9.6 2.7 0.84 8.6 1.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 ETS75294.1 - 2.2 6.7 5.2 0.59 8.6 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 ETS75295.1 - 2.2e-35 121.9 48.4 1.1e-34 119.6 31.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS75295.1 - 2.9e-06 25.7 16.4 3.9e-06 25.3 11.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 ETS75296.1 - 3.6e-36 124.6 0.0 5.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_30 PF02055.11 ETS75297.1 - 1.3e-22 79.6 1.3 3.7e-15 55.1 0.6 2.5 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 ETS75297.1 - 5.1e-16 58.5 2.6 9.9e-15 54.3 0.0 2.2 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_76 PF03663.9 ETS75298.1 - 8.2e-148 492.7 19.8 9.9e-148 492.4 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS75298.1 - 0.014 14.4 7.5 0.51 9.3 0.2 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF4385 PF14328.1 ETS75299.1 - 2.7e-56 189.5 4.7 3.4e-56 189.1 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) SspO PF08175.7 ETS75299.1 - 0.14 12.5 3.5 0.29 11.4 2.4 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein O family Tim17 PF02466.14 ETS75300.1 - 2.7e-11 43.6 7.4 3.9e-11 43.0 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.7 ETS75300.1 - 0.098 12.0 7.5 0.058 12.8 3.4 1.8 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 ETS75300.1 - 0.15 11.7 6.4 0.89 9.2 4.0 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain UCH PF00443.24 ETS75301.1 - 1.3e-37 129.4 0.1 2.4e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS75301.1 - 3.2e-13 49.8 0.6 5.3e-07 29.3 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Methyltransf_16 PF10294.4 ETS75302.1 - 5.1e-17 61.8 0.0 1.2e-16 60.7 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 ETS75302.1 - 6.2e-07 28.8 0.1 8.3e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ETS75302.1 - 9.7e-06 26.1 0.2 1.8e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS75302.1 - 1.6e-05 24.3 0.1 2.7e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 ETS75302.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 ETS75302.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETS75302.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 ETS75302.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Hydrophobin_2 PF06766.6 ETS75303.1 - 1.3e-24 85.6 10.0 1.6e-24 85.3 6.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin HET PF06985.6 ETS75305.1 - 9.2e-13 48.5 0.0 1e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 ETS75306.1 - 7.9e-18 64.6 0.9 9.9e-16 57.7 0.6 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS75306.1 - 4.8e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75306.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS75306.1 - 0.0012 17.7 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS75306.1 - 0.0023 18.0 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS75306.1 - 0.003 16.4 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS75306.1 - 0.0031 17.8 0.1 0.0074 16.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS75306.1 - 0.012 14.4 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase TrkA_N PF02254.13 ETS75306.1 - 0.013 15.4 0.5 0.074 13.0 0.1 2.2 2 1 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 ETS75306.1 - 0.041 12.7 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS75306.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS75306.1 - 0.13 11.3 0.1 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_C PF05199.8 ETS75307.1 - 1.9e-35 122.2 0.1 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS75308.1 - 2.9e-07 29.9 0.0 3.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS75309.1 - 1.4e-35 122.8 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS75309.1 - 3.1e-06 26.3 0.1 5.1e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75309.1 - 9.5e-06 25.5 0.1 2.4e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS75309.1 - 1.6e-05 23.9 0.2 5.5e-05 22.1 0.1 1.8 2 1 1 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 ETS75309.1 - 6.4e-05 22.0 0.0 8.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS75309.1 - 0.00017 20.7 0.4 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETS75309.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75309.1 - 0.0031 16.0 0.0 0.0043 15.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 ETS75309.1 - 0.015 15.0 0.1 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS75309.1 - 0.053 12.1 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 ETS75309.1 - 0.092 12.7 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS75309.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) LysM PF01476.15 ETS75311.1 - 2.8e-09 36.6 0.0 0.018 14.8 0.0 3.4 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.23 ETS75312.1 - 2.2e-74 250.9 0.2 3.7e-74 250.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS75312.1 - 7.6e-07 29.0 7.1 7.6e-07 29.0 4.9 5.6 5 0 0 5 5 5 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 ETS75312.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 LysM PF01476.15 ETS75314.1 - 8.7e-05 22.3 0.0 0.42 10.5 0.0 3.3 3 0 0 3 3 3 2 LysM domain CarbpepA_inh PF02977.10 ETS75314.1 - 1.2 8.7 5.9 7.9 6.1 0.1 4.0 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Sporozoite_P67 PF05642.6 ETS75314.1 - 9.1 3.9 14.4 4.5 5.0 2.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nop PF01798.13 ETS75315.1 - 6.8e-59 197.4 0.1 1.5e-58 196.3 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 ETS75315.1 - 2.6e-17 62.7 0.0 2.6e-17 62.7 0.0 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOSIC PF08060.8 ETS75315.1 - 5e-17 61.4 0.0 1.1e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain GAGA_bind PF06217.7 ETS75315.1 - 0.092 12.6 10.3 0.15 12.0 7.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 ETS75315.1 - 2 8.0 26.6 4.1 7.0 18.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sugar_tr PF00083.19 ETS75316.1 - 1e-107 360.5 21.0 1.2e-107 360.2 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75316.1 - 1.6e-24 86.3 33.0 4.7e-16 58.4 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 ETS75317.1 - 2.7e-46 158.1 0.1 3.4e-46 157.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75317.1 - 3.8e-06 26.8 0.5 1e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS75317.1 - 0.0007 19.7 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS75317.1 - 0.11 12.3 0.3 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 ETS75318.1 - 2.8e-09 36.1 5.9 3.1e-09 36.0 4.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS75319.1 - 5.3e-21 74.6 0.4 9e-21 73.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 ETS75320.1 - 7e-51 172.8 0.0 1.1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75320.1 - 6.3e-30 104.1 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS75320.1 - 2e-06 27.0 0.0 3.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETS75320.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 ETS75321.1 - 7.2e-05 21.9 0.0 0.045 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETS75321.1 - 0.0002 20.5 0.0 0.00063 18.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.20 ETS75323.1 - 0.0044 16.8 2.9 0.0095 15.7 0.2 2.5 2 0 0 2 2 2 1 F5/8 type C domain Trehalase PF01204.13 ETS75323.1 - 0.015 13.9 1.8 0.027 13.1 1.2 1.4 1 1 0 1 1 1 0 Trehalase adh_short PF00106.20 ETS75325.1 - 6.1e-13 49.0 1.1 2.6e-12 46.9 0.2 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS75325.1 - 1.1e-07 31.6 0.4 8.6e-07 28.7 0.2 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 ETS75325.1 - 8.7e-06 25.3 0.0 2.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS75325.1 - 0.022 14.7 0.1 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding BLVR PF06375.6 ETS75325.1 - 0.085 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Glyco_transf_5 PF08323.6 ETS75325.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain COesterase PF00135.23 ETS75326.1 - 1.4e-91 307.8 0.6 3.9e-87 293.1 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS75326.1 - 2.7e-08 33.6 0.1 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold JSRP PF15312.1 ETS75326.1 - 0.095 12.6 0.3 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Fungal_trans_2 PF11951.3 ETS75327.1 - 1.3e-05 23.9 0.2 2.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_4 PF13147.1 ETS75328.1 - 8.8e-23 81.7 0.5 5.3e-22 79.1 0.3 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS75328.1 - 7.1e-20 71.9 0.0 3.1e-09 36.9 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 ETS75328.1 - 1.2e-10 41.1 0.2 2.1e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS75328.1 - 4.4e-10 39.2 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S15 PF02129.13 ETS75328.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TatD_DNase PF01026.16 ETS75328.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase adh_short PF00106.20 ETS75329.1 - 7.3e-14 52.0 0.0 3e-13 50.0 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 ETS75329.1 - 0.044 13.2 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3425 PF11905.3 ETS75330.1 - 1.9e-31 108.7 2.7 3.1e-31 108.0 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PDEase_II PF02112.10 ETS75330.1 - 0.018 13.9 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Abhydrolase_5 PF12695.2 ETS75331.1 - 1.1e-14 54.4 0.0 4.5e-14 52.4 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75331.1 - 5.8e-13 49.2 0.2 9.4e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS75331.1 - 1.3e-06 27.8 0.2 1e-05 24.9 0.1 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 ETS75331.1 - 1.6e-05 24.5 0.3 2.2e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 ETS75331.1 - 0.0012 17.4 0.0 0.0017 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 ETS75331.1 - 0.0039 16.9 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 ETS75331.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0020 PF01170.13 ETS75331.1 - 0.018 14.6 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Chlorophyllase2 PF12740.2 ETS75331.1 - 0.02 13.8 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme FAD_binding_4 PF01565.18 ETS75332.1 - 4.8e-15 55.2 0.1 1.2e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS75332.1 - 4.6e-10 39.2 0.4 9.5e-10 38.2 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.8 ETS75333.1 - 2.7e-14 53.0 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS75333.1 - 3.8e-09 36.7 0.1 5.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 ETS75334.1 - 8.9e-71 238.7 0.0 1.1e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ACR_tran PF00873.14 ETS75334.1 - 0.022 12.2 0.0 0.03 11.7 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HET PF06985.6 ETS75336.1 - 1.3e-31 109.6 1.0 1.3e-31 109.6 0.7 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mucin PF01456.12 ETS75337.1 - 0.00089 19.0 70.2 0.0055 16.4 23.1 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 ETS75337.1 - 8 4.1 41.0 0.027 12.3 8.1 2.1 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Ribonuclease PF00545.15 ETS75338.1 - 2.6e-18 65.8 0.1 3.4e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 ribonuclease Tmemb_14 PF03647.8 ETS75339.1 - 3.9e-26 91.2 2.3 4.3e-26 91.1 1.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.16 ETS75339.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.9 4 0 0 4 4 4 0 Gram positive anchor Peptidase_C97 PF05903.9 ETS75340.1 - 0.00026 20.7 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_M8 PF01457.11 ETS75340.1 - 0.024 12.9 0.0 0.032 12.5 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin ADH_zinc_N PF00107.21 ETS75341.1 - 2.1e-12 46.7 0.0 3.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS75341.1 - 1e-06 28.4 0.0 2.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS75341.1 - 0.053 14.4 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ank_2 PF12796.2 ETS75344.1 - 8.4e-75 247.1 20.8 3.1e-19 69.1 0.0 3.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ras PF00071.17 ETS75344.1 - 4.9e-47 159.3 0.0 8.1e-47 158.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank PF00023.25 ETS75344.1 - 3.6e-36 121.1 14.0 9.5e-06 25.1 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 ETS75344.1 - 5.7e-30 103.1 13.5 6e-06 26.6 0.1 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75344.1 - 5.7e-27 91.0 5.5 0.0014 18.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETS75344.1 - 8.5e-24 83.0 8.4 1.2e-05 25.3 0.1 6.1 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Miro PF08477.8 ETS75344.1 - 3.3e-12 46.9 0.0 2.1e-11 44.3 0.0 2.3 2 1 0 2 2 1 1 Miro-like protein PGAP1 PF07819.8 ETS75344.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS75344.1 - 0.0023 17.2 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.16 ETS75344.1 - 0.0074 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Cutinase PF01083.17 ETS75344.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Cutinase MMR_HSR1 PF01926.18 ETS75344.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 ETS75344.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ADC PF06314.6 ETS75345.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) GMC_oxred_N PF00732.14 ETS75346.1 - 5.1e-55 186.7 0.0 7.1e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS75346.1 - 1.3e-35 122.8 0.1 2.8e-35 121.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.14 ETS75346.1 - 1.5e-17 63.7 0.4 5.2e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 ETS75346.1 - 0.00078 18.4 0.1 0.0027 16.6 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS75346.1 - 0.0011 18.9 0.0 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75346.1 - 0.0019 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS75346.1 - 0.0039 16.9 0.3 0.12 12.0 0.0 3.3 5 0 0 5 5 5 1 FAD-NAD(P)-binding SE PF08491.5 ETS75346.1 - 0.014 14.2 0.0 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 ETS75346.1 - 0.015 14.2 0.7 0.052 12.4 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS75346.1 - 0.041 13.9 0.0 0.18 11.8 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS75346.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 ETS75346.1 - 0.092 13.1 0.9 7.2 7.1 0.0 3.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75346.1 - 0.12 10.7 0.0 0.34 9.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Peptidase_M35 PF02102.10 ETS75347.1 - 2.7e-63 213.7 20.9 3.3e-63 213.5 14.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 ETS75347.1 - 3.1e-11 43.9 1.5 3.1e-11 43.9 1.0 2.1 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase TOBE_2 PF08402.5 ETS75347.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 TOBE domain Peptidase_MA_2 PF13485.1 ETS75349.1 - 2.5e-07 30.7 0.2 4.7e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 ETS75349.1 - 0.00057 19.8 0.1 0.0016 18.4 0.1 1.7 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Gemin7 PF11095.3 ETS75349.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF2235 PF09994.4 ETS75350.1 - 6.9e-64 215.8 0.0 9.3e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.11 ETS75350.1 - 0.13 11.6 0.3 0.35 10.2 0.0 1.7 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase NACHT PF05729.7 ETS75351.1 - 8e-10 38.6 0.0 2.5e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS75351.1 - 4.3e-06 26.8 0.1 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 ETS75351.1 - 0.0029 17.7 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 ETS75351.1 - 0.004 17.2 0.0 0.025 14.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS75351.1 - 0.0093 15.4 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_23 PF13476.1 ETS75351.1 - 0.022 15.0 0.7 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS75351.1 - 0.03 14.6 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 ETS75351.1 - 0.066 12.0 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 ETS75351.1 - 0.1 12.9 0.0 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS75351.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 ETS75351.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS75351.1 - 0.19 11.5 0.1 0.64 9.8 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain NUMOD1 PF07453.8 ETS75351.1 - 0.21 11.5 1.4 0.64 9.9 0.0 2.6 2 0 0 2 2 2 0 NUMOD1 domain DUF3328 PF11807.3 ETS75352.1 - 5.7e-17 62.1 0.2 7e-17 61.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS75353.1 - 4.7e-23 82.0 1.8 1.2e-22 80.6 1.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS75354.1 - 4.2e-18 65.8 0.1 5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DDE_Tnp_IS66 PF03050.9 ETS75354.1 - 0.081 12.1 0.1 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Transposase IS66 family DUF3328 PF11807.3 ETS75355.1 - 9.1e-34 117.0 0.4 1.1e-33 116.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Spin-Ssty PF02513.12 ETS75356.1 - 5.8e-13 48.1 4.8 1.3 8.6 0.0 6.1 5 1 1 6 6 6 6 Spin/Ssty Family Chromo PF00385.19 ETS75356.1 - 9.1e-05 22.0 14.5 9.5 5.9 0.1 5.9 1 1 2 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain EAF PF09816.4 ETS75356.1 - 0.0023 17.8 0.3 0.88 9.5 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase II transcription elongation factor DUF3224 PF11528.3 ETS75356.1 - 0.035 13.6 1.5 6.9 6.1 0.1 2.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3224) Integrase_DNA PF02920.10 ETS75356.1 - 0.71 9.3 19.8 14 5.1 0.1 5.0 1 1 4 5 5 5 0 DNA binding domain of tn916 integrase DUF3921 PF13060.1 ETS75356.1 - 5.3 7.0 10.0 1.9e+02 1.9 0.2 5.0 5 1 1 6 6 6 0 Protein of unknown function (DUF3921) Amastin PF07344.6 ETS75357.1 - 0.00037 20.1 8.9 0.00067 19.3 6.1 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 ETS75357.1 - 0.00079 19.1 5.8 0.00079 19.1 4.0 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Herpes_glycop PF01528.11 ETS75357.1 - 1.4 7.5 11.4 2.1 6.9 7.9 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Acyl_transf_3 PF01757.17 ETS75358.1 - 7.5e-18 64.4 24.5 1.5e-17 63.4 17.0 1.5 1 0 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 ETS75358.1 - 7e-05 22.2 2.2 7e-05 22.2 1.6 2.9 2 2 0 3 3 3 1 Protein of unknown function (DUF1624) DUF4013 PF13197.1 ETS75358.1 - 0.0011 18.3 2.1 0.0011 18.3 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4013) LrgB PF04172.11 ETS75359.1 - 0.032 13.3 1.4 0.045 12.9 0.9 1.1 1 0 0 1 1 1 0 LrgB-like family MAGP PF05507.6 ETS75360.1 - 0.075 12.8 0.4 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) DUF3328 PF11807.3 ETS75361.1 - 3e-25 89.1 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 ETS75362.1 - 9.4e-06 24.6 0.6 1.5e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.17 ETS75363.1 - 9.2e-89 298.4 0.0 1.3e-88 297.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ABC_tran PF00005.22 ETS75364.1 - 8e-40 136.3 0.1 6.9e-20 71.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS75364.1 - 1.8e-37 129.2 26.8 1.2e-24 87.2 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS75364.1 - 2e-14 54.2 0.1 9.4e-06 25.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 ETS75364.1 - 4.7e-13 48.8 1.5 4.2e-05 22.8 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS75364.1 - 2.7e-08 33.2 0.5 0.00093 18.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS75364.1 - 5.2e-08 33.0 0.5 0.015 15.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS75364.1 - 1.7e-06 28.8 0.0 0.049 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 ETS75364.1 - 2.7e-06 27.6 0.0 0.05 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS75364.1 - 3.6e-06 26.0 0.3 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 ETS75364.1 - 1.1e-05 25.3 0.4 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 ETS75364.1 - 1.5e-05 25.0 2.9 0.057 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS75364.1 - 2.3e-05 23.9 0.1 0.2 11.1 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family Miro PF08477.8 ETS75364.1 - 6.1e-05 23.4 0.1 0.018 15.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 ETS75364.1 - 6.2e-05 23.4 0.1 0.3 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS75364.1 - 0.00016 20.9 0.2 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS75364.1 - 0.00019 20.8 0.0 0.013 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS75364.1 - 0.00045 20.1 0.1 0.54 10.2 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS75364.1 - 0.00099 18.6 0.2 0.19 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 ETS75364.1 - 0.0023 17.6 1.3 0.78 9.4 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS75364.1 - 0.0026 17.6 0.9 0.85 9.5 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 ETS75364.1 - 0.0026 17.5 0.8 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family RNA_helicase PF00910.17 ETS75364.1 - 0.004 17.3 0.1 2.3 8.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase TrwB_AAD_bind PF10412.4 ETS75364.1 - 0.0046 15.6 0.0 1.5 7.3 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 ETS75364.1 - 0.012 15.5 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS75364.1 - 0.025 13.6 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 ETS75364.1 - 0.026 14.2 0.6 0.57 9.8 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 ETS75364.1 - 0.028 14.3 0.1 5.1 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.10 ETS75364.1 - 0.033 12.8 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 ETS75364.1 - 0.037 13.7 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 ETS75364.1 - 0.04 13.3 1.1 0.39 10.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 ETS75364.1 - 0.057 12.3 0.0 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 ETS75364.1 - 0.061 12.2 0.2 0.99 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 ETS75364.1 - 0.065 11.9 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 ETS75364.1 - 0.18 11.7 0.2 2.7 7.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 ETS75364.1 - 0.23 10.9 0.8 1.2 8.5 0.3 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 ETS75364.1 - 0.31 10.5 0.7 5 6.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 ETS75364.1 - 0.33 9.9 0.0 9.2 5.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF3290 PF11694.3 ETS75364.1 - 3.2 7.4 5.3 23 4.6 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) HET PF06985.6 ETS75366.1 - 0.0026 17.9 0.1 0.0043 17.2 0.1 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Asp_Glu_race PF01177.17 ETS75367.1 - 1.1e-24 87.5 0.1 1.3e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Ank_2 PF12796.2 ETS75369.1 - 2.7e-18 66.1 0.0 7.5e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.7 ETS75369.1 - 1.9e-13 50.4 0.0 5.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 ETS75369.1 - 6e-13 47.8 0.7 0.00013 21.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS75369.1 - 7.4e-10 39.0 0.5 0.0039 17.6 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS75369.1 - 2e-08 34.1 1.8 0.0041 17.3 0.1 4.7 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75369.1 - 4.1e-08 32.7 0.1 0.049 13.8 0.0 5.4 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.1 ETS75369.1 - 4.1e-06 26.9 0.0 4.3e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETS75369.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 ETS75369.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 ETS75369.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 ETS75369.1 - 0.047 13.5 1.9 0.65 9.8 0.3 2.9 2 1 0 2 2 2 0 AAA domain Lipocalin_5 PF13924.1 ETS75370.1 - 8.6e-20 70.8 0.0 1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain GMC_oxred_N PF00732.14 ETS75371.1 - 5.4e-57 193.2 0.0 6.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS75371.1 - 3.4e-32 111.7 0.2 9.6e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 ETS75371.1 - 1.2e-10 40.8 0.0 0.00013 21.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75371.1 - 0.00013 21.8 0.8 0.00038 20.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS75371.1 - 0.0005 19.0 0.0 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS75371.1 - 0.023 14.5 0.0 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS75371.1 - 0.032 13.0 0.5 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS75371.1 - 0.04 13.9 0.1 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS75371.1 - 0.2 10.0 0.3 4 5.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Dynamin_N PF00350.18 ETS75372.1 - 4.5e-28 98.1 0.0 8.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS75372.1 - 1.9e-13 49.8 0.0 5.1e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 ETS75372.1 - 0.00012 21.9 0.0 0.00057 19.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS75372.1 - 0.0005 20.5 0.0 0.0019 18.6 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 ETS75372.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 ETS75372.1 - 0.078 12.9 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Peptidase_C97 PF05903.9 ETS75373.1 - 0.0025 17.5 0.2 0.0045 16.7 0.1 1.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain PA14_2 PF10528.4 ETS75374.1 - 4.1e-26 91.1 0.5 4.1e-26 91.1 0.3 2.4 2 0 0 2 2 2 1 GLEYA domain Caldesmon PF02029.10 ETS75375.1 - 0.026 12.9 29.7 0.025 13.0 14.3 2.3 2 0 0 2 2 2 0 Caldesmon EthD PF07110.6 ETS75376.1 - 0.0027 18.6 0.1 0.17 12.8 0.0 2.1 1 1 0 1 1 1 1 EthD domain Amidohydro_4 PF13147.1 ETS75377.1 - 1.5e-24 87.4 0.1 4.8e-24 85.8 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS75377.1 - 1.4e-15 57.8 0.4 1.2e-07 31.7 0.0 3.3 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS75377.1 - 1.7e-11 43.7 1.0 1.7e-11 43.7 0.7 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS75377.1 - 5.6e-11 42.2 0.0 2.3e-07 30.4 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family TatD_DNase PF01026.16 ETS75377.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 1 0 1 1 1 0 TatD related DNase CN_hydrolase PF00795.17 ETS75378.1 - 1.7e-20 73.1 0.0 9.7e-20 70.7 0.0 2.1 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase DUF1599 PF07659.6 ETS75382.1 - 0.021 14.8 0.1 0.056 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1599) TPR_11 PF13414.1 ETS75383.1 - 5.8e-06 25.8 0.2 0.064 12.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 ETS75383.1 - 0.00062 19.6 1.3 0.0095 15.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TilS PF09179.6 ETS75383.1 - 0.073 13.0 2.1 2.6 8.1 0.0 3.6 3 0 0 3 3 3 0 TilS substrate binding domain TPR_1 PF00515.23 ETS75383.1 - 0.47 10.1 2.2 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS75383.1 - 1.2 9.2 8.4 6.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PAN_4 PF14295.1 ETS75384.1 - 2.7e-07 30.1 18.1 4.4e-05 23.0 1.6 3.2 2 1 0 2 2 2 2 PAN domain MANEC PF07502.9 ETS75384.1 - 1.9e-05 24.5 5.3 0.082 12.9 0.0 2.8 1 1 0 2 2 2 2 MANEC domain zf-Tim10_DDP PF02953.10 ETS75384.1 - 0.11 11.8 4.4 1.7 8.0 0.7 2.7 2 0 0 2 2 2 0 Tim10/DDP family zinc finger LigD_N PF13298.1 ETS75384.1 - 0.17 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Mucin PF01456.12 ETS75384.1 - 10 5.9 44.0 0.035 13.8 5.0 3.2 2 1 1 3 3 3 0 Mucin-like glycoprotein DUF2236 PF09995.4 ETS75385.1 - 2.6e-57 193.9 0.7 3.3e-57 193.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.3 ETS75386.1 - 6.7e-29 100.4 1.4 1.5e-28 99.3 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Cyt-b5 PF00173.23 ETS75387.1 - 2.3e-20 72.1 0.5 3.2e-20 71.6 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 ETS75387.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.17 ETS75388.1 - 4.1e-20 72.4 0.0 7.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS75388.1 - 9.8e-05 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain T2SF PF00482.18 ETS75388.1 - 0.02 14.8 0.2 0.35 10.7 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Semialdhyde_dh PF01118.19 ETS75388.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.9 ETS75389.1 - 3.6e-111 371.1 3.6 4.9e-111 370.6 2.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 ETS75389.1 - 1.4e-18 67.1 5.9 1.4e-18 67.1 4.1 2.1 2 0 0 2 2 2 1 X8 domain MFS_1 PF07690.11 ETS75390.1 - 3.3e-24 85.2 40.1 3.3e-24 85.2 27.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily AIG2_2 PF13772.1 ETS75391.1 - 9.1e-08 32.1 0.0 0.001 19.1 0.0 2.6 3 0 0 3 3 3 2 AIG2-like family AIG2 PF06094.7 ETS75391.1 - 2e-05 24.9 0.0 3.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family DUF2070 PF09843.4 ETS75391.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Rpn3_C PF08375.6 ETS75392.1 - 3.5e-24 84.9 1.5 3.5e-24 84.9 1.0 2.4 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 ETS75392.1 - 1.4e-20 73.5 0.7 1e-19 70.7 0.0 2.7 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 ETS75392.1 - 0.0064 16.3 0.6 0.02 14.7 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TFIID_20kDa PF03847.8 ETS75394.1 - 9.2e-18 64.3 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.5 ETS75396.1 - 1.3e-53 182.3 5.3 2.4e-52 178.1 3.6 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 ETS75396.1 - 0.0098 15.5 2.4 0.012 15.2 1.7 1.3 1 0 0 1 1 1 1 IncA protein Ribosomal_60s PF00428.14 ETS75396.1 - 0.12 12.7 5.1 43 4.6 0.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein CDC45 PF02724.9 ETS75396.1 - 0.13 10.2 3.7 0.18 9.8 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DSBA PF01323.15 ETS75397.1 - 5.4e-34 117.4 0.0 6.2e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETS75397.1 - 5.8e-05 23.1 0.0 0.00013 21.9 0.0 1.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS75397.1 - 0.001 19.2 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_5 PF13743.1 ETS75397.1 - 0.0078 15.7 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 ETS75397.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain zf-XS PF03470.9 ETS75397.1 - 0.077 13.0 0.6 4.1 7.5 0.1 2.3 2 0 0 2 2 2 0 XS zinc finger domain Polyketide_cyc2 PF10604.4 ETS75398.1 - 1.6e-07 31.5 0.3 1.8e-07 31.4 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2578 PF10843.3 ETS75398.1 - 0.073 12.7 0.4 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) Abhydrolase_3 PF07859.8 ETS75399.1 - 1.1e-44 152.6 0.4 1.8e-44 151.8 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS75399.1 - 0.00068 18.9 0.4 0.003 16.8 0.2 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 ETS75399.1 - 0.0043 15.8 1.6 0.011 14.5 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS75399.1 - 0.042 13.6 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.6 ETS75399.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Fungal_trans PF04082.13 ETS75400.1 - 2.4e-23 82.3 0.5 3.6e-23 81.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75400.1 - 1e-06 28.5 13.0 1.9e-06 27.6 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 ETS75400.1 - 0.41 10.6 6.3 0.81 9.7 4.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Ribosomal_S2 PF00318.15 ETS75401.1 - 5.8e-49 166.1 0.0 1.2e-48 165.0 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S2 Cpn60_TCP1 PF00118.19 ETS75402.1 - 1.6e-139 465.6 3.5 1.9e-139 465.4 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 ETS75402.1 - 0.064 13.0 0.7 1.4 8.7 0.1 2.7 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) PAH PF02671.16 ETS75404.1 - 1e-09 37.8 2.0 7e-09 35.1 1.4 2.0 1 1 0 1 1 1 1 Paired amphipathic helix repeat AAA_26 PF13500.1 ETS75404.1 - 0.001 18.7 0.2 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain TetR_C_6 PF13977.1 ETS75404.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Bacterial transcriptional repressor Corona_nucleoca PF00937.13 ETS75404.1 - 0.1 11.5 1.7 0.15 10.9 1.2 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1680 PF07944.7 ETS75405.1 - 1.7e-133 445.6 0.1 1.9e-133 445.4 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Kelch_1 PF01344.20 ETS75405.1 - 0.055 13.0 0.4 17 5.0 0.0 3.2 2 1 1 3 3 3 0 Kelch motif MRJP PF03022.11 ETS75406.1 - 1.2e-25 90.3 0.0 1.7e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein Mito_carr PF00153.22 ETS75407.1 - 3.3e-59 196.6 5.0 1.8e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein XPG_N PF00752.12 ETS75408.1 - 3.6e-31 107.4 0.0 9.4e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 ETS75408.1 - 7.9e-30 102.7 1.0 1e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 ETS75408.1 - 6.3e-06 26.3 0.1 2.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Abhydrolase_3 PF07859.8 ETS75409.1 - 3.3e-53 180.3 0.0 4.1e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS75409.1 - 0.00098 18.3 0.3 0.26 10.4 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 ETS75409.1 - 0.0028 16.4 0.3 0.0051 15.5 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS75409.1 - 0.0057 16.4 0.0 0.0078 15.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS75409.1 - 0.054 12.1 0.4 0.33 9.5 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) CHU_C PF13585.1 ETS75410.1 - 0.035 13.9 0.4 0.067 13.0 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Zip PF02535.17 ETS75410.1 - 0.052 12.5 2.0 0.057 12.4 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.4 ETS75410.1 - 4 6.8 11.4 6.1 6.2 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 ETS75410.1 - 6.3 4.9 7.4 7.6 4.6 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein FBPase PF00316.15 ETS75411.1 - 3.2e-51 174.0 0.0 4.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase ADH_N PF08240.7 ETS75413.1 - 6.3e-12 45.2 0.6 2.5e-11 43.3 0.4 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS75413.1 - 1.4e-07 31.1 0.3 2.2e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAGAT PF03982.8 ETS75413.1 - 0.011 14.5 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Eno-Rase_NADH_b PF12242.3 ETS75413.1 - 0.052 13.3 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acyl-CoA_dh_1 PF00441.19 ETS75414.1 - 1.1e-39 135.9 0.1 1.6e-39 135.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS75414.1 - 2.3e-20 71.8 0.1 4.4e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS75414.1 - 3.9e-19 69.2 0.0 8.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 ETS75414.1 - 4.5e-17 61.6 0.3 8.4e-17 60.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 ETS75414.1 - 8.6e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain V-ATPase_H_C PF11698.3 ETS75414.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Cys_rich_VLP PF14194.1 ETS75414.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP Fe-S_biosyn PF01521.15 ETS75415.1 - 5.3e-12 45.6 0.0 8.8e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Apc15p PF05841.6 ETS75415.1 - 9 7.0 8.3 2.5 8.8 3.2 2.0 2 1 0 2 2 2 0 Apc15p protein Lgl_C PF08596.5 ETS75416.1 - 5.5e-117 390.5 0.0 9.3e-117 389.8 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 ETS75416.1 - 4.1e-07 29.6 0.7 0.0076 16.0 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETS75416.1 - 0.009 15.4 0.0 2.2 7.8 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 ETS75416.1 - 0.044 13.2 0.0 2.7 7.3 0.0 3.0 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 ETS75416.1 - 0.051 12.3 0.0 2.4 6.7 0.0 2.7 2 1 0 2 2 2 0 Nup133 N terminal like AAA_12 PF13087.1 ETS75417.1 - 7e-40 136.5 0.0 1.5e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS75417.1 - 9.1e-27 94.1 0.0 2.1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS75417.1 - 4.6e-08 32.6 0.3 1.8e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS75417.1 - 1.9e-07 30.8 0.0 2.2e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS75417.1 - 0.00049 20.1 1.0 0.0029 17.6 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 ETS75417.1 - 0.0018 17.3 0.1 1.2 7.9 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 ETS75417.1 - 0.025 14.4 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4066 PF13278.1 ETS75418.1 - 4.7e-31 107.2 0.0 5.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS75418.1 - 5e-10 39.0 0.0 1.1e-09 37.9 0.0 1.6 1 1 1 2 2 2 1 DJ-1/PfpI family CN_hydrolase PF00795.17 ETS75419.1 - 4.6e-36 123.9 0.1 6.1e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_61 PF03443.9 ETS75420.1 - 1.8e-59 201.2 0.1 1.8e-59 201.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Gln-synt_C PF00120.19 ETS75421.1 - 6.7e-62 208.9 0.0 8e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 ETS75421.1 - 1.5e-18 66.1 0.0 2.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Phosphoesterase PF04185.9 ETS75422.1 - 5e-23 81.9 1.2 5e-23 81.9 0.8 1.7 2 0 0 2 2 2 1 Phosphoesterase family Glyco_hydro_3 PF00933.16 ETS75423.1 - 1.2e-55 188.6 0.0 2.2e-55 187.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS75423.1 - 8.1e-34 117.1 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS75423.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AATase PF07247.7 ETS75424.1 - 9e-22 77.2 0.0 2.4e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 ETS75424.1 - 4.9e-08 32.1 0.2 1.7e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 ETS75424.1 - 5.3e-05 22.9 0.1 0.00013 21.5 0.1 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Ank_2 PF12796.2 ETS75425.1 - 5.1e-38 129.3 4.3 6e-13 48.9 0.1 5.5 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) HET PF06985.6 ETS75425.1 - 5.7e-34 117.2 0.2 9.8e-34 116.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.1 ETS75425.1 - 4.7e-22 75.8 11.7 0.0065 16.6 0.0 9.5 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.25 ETS75425.1 - 4.8e-21 73.4 16.3 0.00012 21.7 0.0 9.2 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 ETS75425.1 - 1.7e-15 57.0 5.5 6.5e-06 26.5 0.0 6.9 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS75425.1 - 4.1e-12 45.9 7.7 2.8e-05 24.2 0.0 5.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) DUF2399 PF09664.5 ETS75425.1 - 0.005 16.7 0.0 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) DUF1835 PF08874.5 ETS75425.1 - 0.17 11.8 2.7 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1835) MFS_1 PF07690.11 ETS75426.1 - 1.6e-29 102.7 22.5 1.6e-29 102.7 15.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS75426.1 - 0.024 14.6 3.6 0.24 11.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1049 PF06305.6 ETS75426.1 - 0.11 12.0 0.8 0.72 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) zf-DHHC PF01529.15 ETS75426.1 - 1 8.7 0.0 1 8.7 0.0 2.7 3 1 1 4 4 4 0 DHHC palmitoyltransferase CoA_transf_3 PF02515.12 ETS75428.1 - 1e-30 106.4 0.0 3.9e-29 101.2 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III adh_short_C2 PF13561.1 ETS75429.1 - 5e-26 91.9 0.1 5.9e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS75429.1 - 4.1e-18 65.8 1.3 5.5e-18 65.4 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.8 ETS75430.1 - 3.5e-49 167.2 0.0 4.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS75430.1 - 1.3e-11 43.9 2.2 4e-11 42.3 1.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS75430.1 - 0.02 14.1 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS75432.1 - 1.6e-26 93.5 0.2 2.2e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS75432.1 - 1.5e-11 44.2 0.7 1.2e-10 41.4 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS75432.1 - 7.9e-10 38.6 0.1 2.5e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS75432.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Pyr_redox_3 PF13738.1 ETS75433.1 - 5.1e-23 82.2 0.0 8.5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS75433.1 - 7.3e-14 50.8 0.1 3.7e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS75433.1 - 4.7e-11 42.1 0.0 2.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS75433.1 - 9e-08 32.0 0.0 1.2e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75433.1 - 2.1e-07 31.0 0.0 0.0034 17.2 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS75433.1 - 4.2e-05 22.7 3.0 0.0031 16.6 0.2 2.8 3 0 0 3 3 3 2 Thi4 family NAD_binding_7 PF13241.1 ETS75433.1 - 0.00071 19.7 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.22 ETS75433.1 - 0.0012 19.1 0.8 1.2 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS75433.1 - 0.0013 18.8 0.3 0.054 13.5 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 ETS75433.1 - 0.0034 16.7 0.9 0.096 12.0 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 ETS75433.1 - 0.0042 16.8 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_2 PF03446.10 ETS75433.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 ETS75433.1 - 0.024 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS75433.1 - 0.2 11.2 2.3 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WSC PF01822.14 ETS75434.1 - 4.1e-70 231.7 77.7 1.5e-18 66.4 11.5 4.1 4 0 0 4 4 4 4 WSC domain Acetyltransf_1 PF00583.19 ETS75436.1 - 0.04 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF2227 PF09988.4 ETS75436.1 - 0.058 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) p450 PF00067.17 ETS75437.1 - 6.4e-60 202.9 0.0 7.8e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 ETS75441.1 - 5.4e-36 123.8 0.0 1.3e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75441.1 - 3.6e-09 36.3 8.1 8.2e-09 35.2 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SP_C-Propep PF08999.5 ETS75441.1 - 0.082 12.3 0.3 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide CN_hydrolase PF00795.17 ETS75442.1 - 6.2e-32 110.4 0.0 8e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp PF00026.18 ETS75443.1 - 1.2e-110 369.7 0.1 1.4e-110 369.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS75443.1 - 8.2e-13 48.6 0.0 2.3e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS75443.1 - 8e-08 32.6 0.1 0.001 19.5 0.0 3.1 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 ETS75443.1 - 6.8e-06 25.7 0.0 8.8e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 ETS75443.1 - 0.13 12.4 0.0 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain FAD_binding_2 PF00890.19 ETS75444.1 - 1.3e-61 208.7 4.2 1.5e-61 208.4 2.9 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS75444.1 - 3.1e-10 39.4 1.9 2.8e-09 36.3 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS75444.1 - 1e-08 35.0 0.7 4.8e-08 32.9 0.5 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS75444.1 - 3.2e-06 26.5 2.6 1.2e-05 24.5 1.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS75444.1 - 1.6e-05 25.1 0.1 3.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS75444.1 - 1.6e-05 24.1 2.1 0.00017 20.7 1.4 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS75444.1 - 2.9e-05 24.0 0.7 8.2e-05 22.5 0.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS75444.1 - 4.4e-05 22.5 3.2 8.2e-05 21.6 0.9 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 ETS75444.1 - 0.00029 19.4 0.4 0.00029 19.4 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 ETS75444.1 - 0.00064 18.8 0.6 0.0036 16.4 0.2 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS75444.1 - 0.0011 19.2 0.1 0.0062 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS75444.1 - 0.012 14.5 0.2 0.023 13.6 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 ETS75444.1 - 0.032 13.7 0.4 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 ETS75444.1 - 0.067 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 ETS75445.1 - 7.1e-33 113.7 29.1 1.2e-31 109.7 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SieB PF14163.1 ETS75445.1 - 0.021 14.3 0.1 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B Lipase_GDSL_2 PF13472.1 ETS75446.1 - 1.9e-14 54.1 0.0 2.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS75446.1 - 5e-12 46.1 0.0 6.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ETS75446.1 - 0.002 17.8 0.0 0.023 14.4 0.0 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family PALP PF00291.20 ETS75447.1 - 3e-46 158.0 0.0 3.8e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SHMT PF00464.14 ETS75448.1 - 2.4e-208 691.3 0.0 2.8e-208 691.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 ETS75448.1 - 6e-05 21.9 0.0 9.1e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETS75448.1 - 0.0043 16.2 0.0 0.0081 15.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.5 ETS75448.1 - 0.18 11.5 0.2 1.4 8.7 0.0 2.5 3 0 0 3 3 3 0 FR47-like protein GST_N_3 PF13417.1 ETS75449.1 - 4.8e-08 33.1 0.0 9.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS75449.1 - 7.6e-05 22.6 0.1 0.0009 19.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS75449.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS75449.1 - 0.023 14.8 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS75449.1 - 0.026 14.4 1.6 0.054 13.4 1.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS75449.1 - 0.091 13.2 0.1 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alpha_L_fucos PF01120.12 ETS75451.1 - 4e-83 279.2 6.2 5.3e-83 278.7 4.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 ETS75451.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_43 PF04616.9 ETS75452.1 - 2.4e-67 227.0 2.4 3e-67 226.6 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Bromodomain PF00439.20 ETS75453.1 - 2.9e-21 75.1 0.3 7.5e-21 73.8 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 ETS75453.1 - 2.9e-10 39.7 0.0 1.2e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Bromodomain associated SPARC_Ca_bdg PF10591.4 ETS75453.1 - 0.43 10.6 5.3 2.1 8.4 3.7 2.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region VanZ PF04892.7 ETS75454.1 - 1.4e-10 41.1 2.6 2.1e-10 40.6 1.8 1.2 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 ETS75454.1 - 0.011 14.8 0.7 0.013 14.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Pyridoxal_deC PF00282.14 ETS75455.1 - 5.6e-74 248.8 0.0 6.8e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 ETS75455.1 - 2.5e-06 26.8 0.0 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 ETS75455.1 - 0.002 16.6 0.0 0.003 16.0 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 ETS75455.1 - 0.0039 15.9 0.0 0.0079 14.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Glyco_transf_20 PF00982.16 ETS75455.1 - 0.2 10.0 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 adh_short PF00106.20 ETS75456.1 - 1e-26 93.8 0.0 1.6e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75456.1 - 6.5e-14 51.9 0.0 8.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS75456.1 - 6e-07 29.1 0.0 9.8e-07 28.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS75456.1 - 2e-05 23.6 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 ETS75456.1 - 0.00019 20.5 0.1 0.00026 20.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 ETS75456.1 - 0.0013 17.7 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS75456.1 - 0.024 14.6 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Abhydrolase_3 PF07859.8 ETS75457.1 - 7.2e-55 185.8 0.1 8.8e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS75457.1 - 4.6e-05 22.3 0.0 7.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS75457.1 - 8.5e-05 21.8 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS75457.1 - 0.0028 17.4 0.1 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS75457.1 - 0.0037 16.5 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3402 PF11882.3 ETS75458.1 - 0.086 11.8 0.1 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) PUF PF00806.14 ETS75459.1 - 1.4e-11 43.2 1.6 1 8.9 0.0 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Peptidase_M20 PF01546.23 ETS75460.1 - 3.8e-24 85.2 0.2 5e-24 84.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS75460.1 - 3.5e-21 75.0 0.0 5.6e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS75460.1 - 0.026 14.2 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Glyco_hyd_65N_2 PF14498.1 ETS75462.1 - 1.9e-50 171.7 0.1 2.5e-50 171.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Stig1 PF04885.8 ETS75463.1 - 0.0019 18.4 16.4 0.0019 18.4 11.4 2.4 1 1 1 2 2 2 1 Stigma-specific protein, Stig1 Ank_2 PF12796.2 ETS75464.1 - 5.5e-37 125.9 5.5 2.5e-08 34.1 0.0 5.8 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS75464.1 - 1.7e-29 101.6 12.5 3.5e-06 27.3 0.2 7.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 ETS75464.1 - 4.6e-28 95.5 10.9 1.4e-05 24.6 0.0 9.2 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 ETS75464.1 - 3.5e-25 87.4 7.8 2.9e-09 36.8 0.5 6.4 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75464.1 - 1.4e-22 77.5 13.6 0.00021 21.2 0.4 9.7 11 0 0 11 11 11 4 Ankyrin repeat Trp_DMAT PF11991.3 ETS75465.1 - 6e-73 246.1 0.0 7.3e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.20 ETS75466.1 - 5e-14 52.5 0.1 8.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75466.1 - 8.3e-07 28.8 0.1 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS75466.1 - 0.038 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 ETS75466.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.22 ETS75468.1 - 1.2e-24 87.1 0.1 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS75468.1 - 3.7e-08 33.1 0.3 5.6e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 ETS75469.1 - 4.5e-30 104.3 0.1 6.6e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.15 ETS75470.1 - 4.2e-34 118.6 2.1 6.6e-34 118.0 1.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 ETS75471.1 - 3.8e-30 105.7 6.8 5.1e-30 105.3 4.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3847 PF12958.2 ETS75473.1 - 0.11 12.2 0.0 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) SecE PF00584.15 ETS75474.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex adh_short PF00106.20 ETS75475.1 - 6.4e-23 81.4 0.2 8.9e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS75475.1 - 3.8e-12 46.4 0.1 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS75475.1 - 5.5e-10 39.1 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3090 PF11290.3 ETS75476.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Sugar_tr PF00083.19 ETS75477.1 - 2.3e-83 280.2 25.8 2.8e-83 279.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75477.1 - 1.4e-29 102.9 23.7 1.6e-20 73.1 4.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 ETS75478.1 - 1.8e-08 34.7 0.1 2.9e-08 33.9 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS75478.1 - 5.8e-06 25.0 0.1 0.018 13.5 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans_2 PF11951.3 ETS75479.1 - 1.7e-45 155.2 1.9 2.5e-45 154.7 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 ETS75480.1 - 5.1e-60 199.8 2.8 2.7e-13 50.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75480.1 - 5.5e-53 174.2 0.6 2.7e-05 23.7 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.1 ETS75480.1 - 4.7e-45 150.5 8.7 2.8e-07 30.5 0.2 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS75480.1 - 5.2e-35 119.2 2.3 3.5e-06 27.3 0.0 8.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75480.1 - 1.5e-34 114.5 1.4 0.0024 17.9 0.0 10.3 11 0 0 11 11 11 8 Ankyrin repeat GATase_7 PF13537.1 ETS75480.1 - 0.056 13.1 0.0 29 4.4 0.0 4.0 3 2 2 5 5 5 0 Glutamine amidotransferase domain CHAT PF12770.2 ETS75481.1 - 1.1e-32 113.3 0.0 1.8e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 CHAT domain MFS_1 PF07690.11 ETS75482.1 - 2e-32 112.3 41.0 2e-32 112.3 28.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.16 ETS75483.1 - 1.9e-105 353.3 0.0 2.2e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 Amidase p450 PF00067.17 ETS75484.1 - 4.2e-53 180.5 0.0 6.2e-31 107.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.21 ETS75485.1 - 4.7e-64 216.3 0.0 8.7e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS75485.1 - 2.2e-57 194.8 0.0 3.3e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 ETS75485.1 - 1.3e-50 172.2 0.0 2.5e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 ETS75485.1 - 5.8e-50 169.4 2.1 1.2e-49 168.4 0.6 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 ETS75485.1 - 5.4e-38 130.5 2.0 4.5e-37 127.5 0.6 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS75485.1 - 7.2e-33 112.9 4.5 3.5e-32 110.7 0.3 3.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS75485.1 - 2.2e-20 72.5 1.4 4.6e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS75485.1 - 2.6e-14 54.2 0.0 1.2e-13 52.0 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 ETS75485.1 - 4.8e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 ETS75486.1 - 1.4e-14 54.5 0.0 1.9e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS75486.1 - 7e-13 48.5 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS75486.1 - 9.7e-08 31.4 0.0 1.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETS75486.1 - 1.6e-07 31.0 0.0 3.9e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 ETS75486.1 - 1.2e-05 23.9 0.0 2.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 ETS75486.1 - 3.1e-05 23.7 0.0 0.00012 21.8 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 ETS75486.1 - 0.00025 20.6 0.0 0.00035 20.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS75486.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 ETS75486.1 - 0.069 12.7 0.1 0.29 10.6 0.0 2.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold p450 PF00067.17 ETS75487.1 - 1.3e-42 145.9 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 ETS75487.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF4131 PF13567.1 ETS75487.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) 2OG-FeII_Oxy PF03171.15 ETS75488.1 - 8.2e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS75488.1 - 4.9e-07 30.2 0.0 8.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Asn_synthase PF00733.16 ETS75489.1 - 4.9e-53 180.2 0.9 9.6e-52 175.9 0.6 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS75489.1 - 3.2e-37 127.0 0.0 5.3e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS75489.1 - 4.9e-34 117.1 0.0 8.7e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ETS75489.1 - 1.3e-05 24.0 0.0 0.12 11.0 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 ETS75489.1 - 0.00026 20.2 0.0 0.0006 19.0 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 ETS75489.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Zn_clus PF00172.13 ETS75490.1 - 2.5e-05 24.0 8.6 4.3e-05 23.3 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.8 ETS75491.1 - 6.5e-52 175.4 0.0 2.2e-51 173.6 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Choline_transpo PF04515.7 ETS75492.1 - 1e-102 343.3 22.5 1e-102 343.3 15.6 2.6 1 1 2 3 3 3 1 Plasma-membrane choline transporter Pex14_N PF04695.8 ETS75492.1 - 0.039 14.0 0.9 0.1 12.6 0.6 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pho88 PF10032.4 ETS75493.1 - 0.13 11.5 0.3 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphate transport (Pho88) Esterase_phd PF10503.4 ETS75495.1 - 2e-21 76.2 1.2 2.6e-21 75.9 0.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS75495.1 - 3.3e-14 52.6 0.9 4.8e-14 52.0 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS75495.1 - 0.00034 20.3 0.4 0.00051 19.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS75495.1 - 0.0033 17.0 0.2 0.0079 15.7 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS75495.1 - 0.016 13.9 0.6 0.021 13.5 0.4 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_1 PF00561.15 ETS75495.1 - 0.029 13.9 0.3 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 ETS75496.1 - 3.8e-15 55.4 25.5 3.8e-15 55.4 17.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Galanin PF01296.13 ETS75496.1 - 0.063 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Galanin Sec23_helical PF04815.10 ETS75496.1 - 0.091 12.2 0.2 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 helical domain RPE65 PF03055.10 ETS75497.1 - 3.4e-123 411.7 0.0 3.8e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CFEM PF05730.6 ETS75498.1 - 0.00071 19.3 6.2 0.00097 18.9 4.3 1.2 1 0 0 1 1 1 1 CFEM domain HsbA PF12296.3 ETS75498.1 - 0.48 10.2 4.2 7.1 6.5 0.4 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A COesterase PF00135.23 ETS75499.1 - 2.6e-91 306.9 2.2 4.7e-81 273.1 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS75499.1 - 0.00026 20.6 0.0 0.0006 19.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_GDSL PF00657.17 ETS75500.1 - 1.2e-13 51.4 3.8 1.3e-13 51.3 1.6 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.16 ETS75501.1 - 1e-95 320.5 0.0 1.2e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETS75501.1 - 5.9e-06 25.4 0.0 0.00022 20.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PAS_4 PF08448.5 ETS75502.1 - 0.068 13.2 0.0 0.86 9.6 0.0 2.4 2 0 0 2 2 2 0 PAS fold Zn_clus PF00172.13 ETS75503.1 - 2.2e-07 30.6 12.1 3.5e-07 30.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 ETS75504.1 - 1.7e-23 82.1 0.4 3.1e-23 81.2 0.2 1.5 1 0 0 1 1 1 1 YEATS family Dynamin_N PF00350.18 ETS75505.1 - 9.6e-16 58.0 0.0 2.5e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETS75505.1 - 2.1e-09 37.3 0.1 8.8e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS75505.1 - 6.8e-07 28.9 0.3 3.6e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 ETS75505.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 ETS75505.1 - 0.015 14.7 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETS75505.1 - 0.027 14.7 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 ETS75505.1 - 0.038 14.4 0.0 0.4 11.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 ETS75505.1 - 1.4 9.2 4.4 10 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain Snf7 PF03357.16 ETS75506.1 - 8e-35 119.7 21.3 1.3e-34 119.0 14.8 1.3 1 0 0 1 1 1 1 Snf7 CaMBD PF02888.11 ETS75506.1 - 0.0059 16.4 3.7 0.0059 16.4 2.5 2.2 1 1 1 2 2 2 1 Calmodulin binding domain Ist1 PF03398.9 ETS75506.1 - 0.012 15.0 6.3 0.024 14.0 4.4 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway V_ATPase_I PF01496.14 ETS75506.1 - 0.012 13.5 3.6 0.015 13.2 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M66 PF10462.4 ETS75506.1 - 0.042 12.7 0.6 0.066 12.0 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 HSCB_C PF07743.8 ETS75506.1 - 0.064 13.7 1.5 0.064 13.7 1.0 2.8 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain ATC_hydrolase PF14196.1 ETS75506.1 - 0.25 11.7 0.1 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Peptidase_S46 PF10459.4 ETS75506.1 - 2.2 6.5 11.4 5 5.4 7.9 1.5 1 1 0 1 1 1 0 Peptidase S46 DFF40 PF09230.5 ETS75506.1 - 2.7 7.3 6.8 2.6 7.3 4.2 1.3 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa Fe-ADH PF00465.14 ETS75507.1 - 1.7e-65 221.0 0.0 2.1e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS75507.1 - 3e-09 36.5 0.1 8.6e-05 21.9 0.0 2.6 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase PP2C PF00481.16 ETS75508.1 - 5.4e-62 209.4 0.1 6.1e-51 173.2 0.0 3.3 1 1 2 3 3 3 3 Protein phosphatase 2C Methyltransf_23 PF13489.1 ETS75510.1 - 1.1e-15 57.6 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75510.1 - 3.1e-07 30.7 0.0 1.3e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS75510.1 - 5.7e-07 29.9 0.0 2.3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS75510.1 - 8.5e-06 26.3 0.0 0.0001 22.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS75510.1 - 0.00015 21.3 0.0 0.05 13.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.12 ETS75510.1 - 0.0078 15.2 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 ETS75510.1 - 0.029 14.7 0.0 0.062 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS75510.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 ETS75510.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 ETS75511.1 - 1.6e-20 73.4 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS75511.1 - 7.6e-09 35.9 0.0 1.8e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75511.1 - 4.7e-08 33.4 0.0 2.4e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS75511.1 - 2.6e-07 30.3 0.0 0.011 15.2 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS75511.1 - 1e-05 26.0 0.1 5.7e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS75511.1 - 9.4e-05 22.7 0.0 0.00026 21.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain SH3_1 PF00018.23 ETS75512.1 - 1.2e-05 24.5 0.7 4e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 ETS75512.1 - 0.0057 16.2 0.0 0.016 14.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain gpW PF02831.10 ETS75512.1 - 0.03 13.8 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 gpW FAD_binding_7 PF03441.9 ETS75513.1 - 2e-88 296.2 0.1 3.8e-88 295.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS75513.1 - 1.3e-36 125.8 0.0 5.9e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 DNA photolyase DUF543 PF04418.7 ETS75516.1 - 1e-29 102.2 0.0 1.1e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 ETS75517.1 - 4.6e-52 176.8 0.6 1.3e-51 175.4 0.1 2.0 2 0 0 2 2 2 1 Urb2/Npa2 family TIM PF00121.13 ETS75520.1 - 1e-92 309.6 1.3 1.1e-92 309.4 0.9 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Flavi_NS1 PF00948.16 ETS75520.1 - 0.005 15.2 0.4 0.0066 14.9 0.2 1.1 1 0 0 1 1 1 1 Flavivirus non-structural Protein NS1 Toprim PF01751.17 ETS75520.1 - 0.026 14.5 0.1 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Toprim domain L51_S25_CI-B8 PF05047.11 ETS75521.1 - 1.1e-14 53.9 0.0 1.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pro_CA PF00484.14 ETS75521.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Carbonic anhydrase U1snRNP70_N PF12220.3 ETS75522.1 - 2.8e-27 94.8 1.7 4.5e-27 94.2 1.2 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 ETS75522.1 - 1.4e-16 59.9 0.1 7.9e-16 57.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS75522.1 - 6.3e-12 45.2 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS75522.1 - 2e-08 33.9 0.0 5.1e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 ETS75523.1 - 2e-21 75.7 0.0 2.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 zf-Tim10_DDP PF02953.10 ETS75524.1 - 1.3e-18 66.0 3.8 1.5e-18 65.8 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger INCENP_ARK-bind PF03941.10 ETS75524.1 - 0.17 11.7 1.1 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Nup188 PF10487.4 ETS75525.1 - 2.8e-33 114.9 2.8 8e-33 113.4 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF1987 PF09345.5 ETS75525.1 - 0.0076 16.0 0.0 2.5 7.9 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1987) IGPS PF00218.16 ETS75526.1 - 7.3e-95 316.8 0.2 1.2e-94 316.1 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 ETS75526.1 - 1.9e-50 170.9 0.0 1.8e-49 167.8 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 ETS75526.1 - 1.6e-46 158.3 0.0 3.7e-44 150.6 0.0 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 ETS75526.1 - 0.00012 21.5 0.1 0.00042 19.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.13 ETS75526.1 - 0.0017 17.2 0.2 0.014 14.2 0.1 2.1 1 1 1 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.9 ETS75526.1 - 0.0073 15.2 0.9 1.2 8.0 0.0 4.0 4 1 1 5 5 5 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.14 ETS75526.1 - 0.25 10.8 2.5 1.1 8.7 0.1 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain MFS_1 PF07690.11 ETS75527.1 - 2.4e-21 75.8 56.4 1.5e-20 73.2 39.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily RA PF00788.18 ETS75528.1 - 6.8e-15 55.3 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 ETS75528.1 - 7.5e-15 54.5 0.0 1.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETS75528.1 - 9e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_4 PF13637.1 ETS75529.1 - 0.069 13.6 0.0 0.44 11.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3936 PF13072.1 ETS75529.1 - 0.085 12.3 0.4 0.22 11.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Asp PF00026.18 ETS75531.1 - 1.3e-09 37.8 0.1 2.1e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Ras PF00071.17 ETS75532.1 - 3.5e-15 55.7 0.0 4.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Ras family DUF1295 PF06966.7 ETS75533.1 - 3.9e-30 104.8 0.1 5.4e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETS75533.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS75533.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 ETS75533.1 - 0.0024 16.4 0.0 0.0038 15.8 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 ETS75533.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase MARVEL PF01284.18 ETS75534.1 - 1.6 8.5 12.1 6.3 6.6 8.5 1.9 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydro_15 PF00723.16 ETS75535.1 - 5.9e-92 308.5 0.5 6.8e-92 308.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pectate_lyase PF03211.8 ETS75536.1 - 2.5e-61 206.7 2.3 2.5e-61 206.7 1.6 1.9 2 0 0 2 2 2 1 Pectate lyase FLO_LFY PF01698.11 ETS75536.1 - 0.96 8.2 10.3 1.4 7.6 7.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP4R2 PF09184.6 ETS75536.1 - 2 7.9 15.1 2.8 7.4 10.5 1.3 1 0 0 1 1 1 0 PPP4R2 Apt1 PF10351.4 ETS75536.1 - 2.3 7.0 14.6 3.1 6.5 10.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TATR PF03430.8 ETS75536.1 - 5.6 5.4 8.4 7.5 5.0 5.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FAM176 PF14851.1 ETS75536.1 - 6.4 6.4 7.9 13 5.4 5.4 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 ETS75536.1 - 7.3 6.9 13.4 0.27 11.5 5.3 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 ETS75537.1 - 5.7e-46 156.8 37.8 5.7e-46 156.8 26.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS75537.1 - 0.0006 18.1 1.1 0.00092 17.5 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 ETS75537.1 - 0.065 11.3 3.8 0.14 10.2 2.6 1.5 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2214 PF09980.4 ETS75537.1 - 0.36 10.5 4.8 1.5 8.5 0.3 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2214) FAD_binding_3 PF01494.14 ETS75538.1 - 5.1e-18 65.2 0.4 7.9e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS75538.1 - 5e-14 51.9 1.0 4.8e-06 25.7 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS75538.1 - 2.7e-06 27.7 0.0 1.5e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS75538.1 - 0.00022 20.7 0.1 0.0008 18.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 ETS75538.1 - 0.00024 21.0 0.1 0.00062 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75538.1 - 0.0043 16.9 0.7 0.01 15.7 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS75538.1 - 0.0047 15.8 0.2 0.012 14.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 ETS75538.1 - 0.016 13.8 0.3 0.45 9.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 ETS75538.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 ETS75538.1 - 0.05 13.3 0.1 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_2 PF12796.2 ETS75539.1 - 6e-22 77.8 0.4 2.9e-13 49.9 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75539.1 - 2.9e-17 61.5 9.2 0.00031 20.3 0.3 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETS75539.1 - 1.5e-14 53.6 3.0 4.8e-05 23.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS75539.1 - 5.9e-13 48.9 2.0 7.2e-05 23.1 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75539.1 - 7.9e-10 38.0 3.1 0.014 15.6 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat Fungal_trans PF04082.13 ETS75541.1 - 3.3e-12 45.8 0.3 6.3e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75541.1 - 6e-09 35.6 10.5 1.1e-08 34.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDP-g_GGTase PF06427.6 ETS75544.1 - 4.8e-63 212.2 0.0 3.5e-62 209.4 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 ETS75544.1 - 1.8e-05 24.2 1.2 6.9e-05 22.2 0.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.9 ETS75545.1 - 3.4e-150 500.7 0.0 6.4e-150 499.8 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 ETS75545.1 - 2.7e-80 269.9 0.0 4e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 ETS75545.1 - 1.9e-49 163.8 14.2 4.5e-09 35.8 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Clathrin PF00637.15 ETS75545.1 - 0.0065 16.0 0.3 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Nup160 PF11715.3 ETS75545.1 - 0.06 11.4 3.6 1.1 7.2 0.1 3.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SAC3_GANP PF03399.11 ETS75546.1 - 7.5e-22 77.8 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 ETS75546.1 - 6.6e-18 64.8 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Sel1 PF08238.7 ETS75547.1 - 1.7e-14 53.8 28.8 4.4e-07 30.3 0.0 7.3 7 0 0 7 7 7 4 Sel1 repeat TPR_8 PF13181.1 ETS75547.1 - 0.00074 19.1 0.2 0.0039 16.8 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS75547.1 - 0.00092 18.7 2.9 0.00096 18.6 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS75547.1 - 0.0048 17.5 1.6 0.0048 17.5 1.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS75547.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS75547.1 - 0.0061 16.1 5.5 0.0077 15.8 0.1 2.8 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 ETS75547.1 - 0.036 13.9 1.6 0.34 10.8 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS75547.1 - 0.037 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS75547.1 - 0.33 11.5 0.1 0.33 11.5 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.18 ETS75548.1 - 6.4e-67 225.4 0.1 9.6e-67 224.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS75548.1 - 1.5e-13 50.4 0.0 3.8e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS75548.1 - 1.3e-09 37.7 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 ETS75548.1 - 0.0016 17.2 0.1 0.0044 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.10 ETS75548.1 - 0.011 15.1 0.2 0.044 13.1 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 Zn-ribbon_8 PF09723.5 ETS75548.1 - 0.043 13.7 1.0 0.12 12.3 0.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Ank_2 PF12796.2 ETS75549.1 - 3.2e-16 59.4 0.1 1.5e-09 38.0 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75549.1 - 3.6e-11 42.2 0.4 0.00021 20.9 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 ETS75549.1 - 8.5e-11 41.7 0.0 2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 ETS75549.1 - 5e-09 36.4 0.3 0.001 19.4 0.0 6.3 6 1 1 7 7 7 2 Ankyrin repeats (many copies) AAA_22 PF13401.1 ETS75549.1 - 8.2e-08 32.4 0.0 3.8e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS75549.1 - 2.1e-07 30.5 0.0 6.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.1 ETS75549.1 - 2.3e-06 27.6 1.9 0.034 14.3 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75549.1 - 2.9e-06 26.9 0.6 0.077 13.2 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat AAA PF00004.24 ETS75549.1 - 2.2e-05 24.6 0.2 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS75549.1 - 0.00011 22.2 1.5 0.0005 20.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 ETS75549.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 ETS75549.1 - 0.0055 16.3 0.1 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 ETS75549.1 - 0.022 14.3 0.1 0.022 14.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 ETS75549.1 - 0.042 13.3 1.1 0.57 9.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 ETS75549.1 - 0.066 14.0 0.0 0.41 11.4 0.0 2.5 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 ETS75549.1 - 0.083 12.3 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TIMELESS_C PF05029.8 ETS75550.1 - 0.013 14.5 13.9 0.019 13.9 9.7 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region Sporozoite_P67 PF05642.6 ETS75550.1 - 0.028 12.3 9.5 0.04 11.8 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 2OG-FeII_Oxy_3 PF13640.1 ETS75550.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.9 ETS75550.1 - 0.94 7.4 18.4 1.4 6.8 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 ETS75550.1 - 4.3 6.9 21.3 10 5.6 14.8 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Prog_receptor PF02161.10 ETS75550.1 - 4.3 6.0 8.6 0.78 8.4 3.5 1.5 2 0 0 2 2 2 0 Progesterone receptor CobT PF06213.7 ETS75550.1 - 5 6.1 28.0 11 5.0 19.4 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CFEM PF05730.6 ETS75552.1 - 3.2e-15 55.6 13.3 4.6e-15 55.1 9.2 1.2 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 ETS75552.1 - 2.3 8.3 9.3 1.9 8.6 5.3 1.7 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain peroxidase PF00141.18 ETS75553.1 - 1.5e-89 299.4 0.0 2.1e-47 161.5 0.0 2.1 2 0 0 2 2 2 2 Peroxidase PAN_4 PF14295.1 ETS75554.1 - 0.0041 16.8 1.8 0.0041 16.8 1.2 2.7 2 1 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.14 ETS75554.1 - 0.0065 16.4 17.4 0.0065 16.4 12.1 2.7 3 0 0 3 3 3 1 Chitin recognition protein AAA PF00004.24 ETS75555.1 - 1.2e-15 57.9 0.0 2.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS75555.1 - 0.0022 18.1 0.1 0.14 12.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS75555.1 - 0.0034 17.3 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 ETS75555.1 - 0.0082 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 ETS75555.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETS75555.1 - 0.017 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 ETS75555.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 ETS75555.1 - 0.021 13.7 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 ETS75555.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.1 ETS75555.1 - 0.044 14.6 0.4 0.18 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS75555.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 ETS75555.1 - 0.095 13.0 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS75555.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS75555.1 - 0.11 11.9 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 ETS75555.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4606 PF15379.1 ETS75555.1 - 0.2 11.7 18.0 24 5.0 0.0 7.4 2 1 7 9 9 9 0 Domain of unknown function (DUF4606) PIF1 PF05970.9 ETS75555.1 - 0.24 10.2 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF1289 PF06945.8 ETS75555.1 - 0.29 10.6 40.6 4.6 6.7 0.1 10.2 11 0 0 11 11 11 0 Protein of unknown function (DUF1289) EB1 PF03271.12 ETS75557.1 - 4.6e-18 64.9 0.6 9.2e-18 64.0 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 ETS75557.1 - 3.5e-07 30.2 0.9 5.4e-07 29.6 0.7 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 ETS75557.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain adh_short PF00106.20 ETS75558.1 - 2.1e-09 37.5 2.9 3.8e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS75558.1 - 0.0032 17.1 1.6 0.011 15.4 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS75558.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 ETS75559.1 - 2e-53 181.5 0.0 2.6e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 ETS75560.1 - 1.2e-50 172.3 42.5 1.6e-50 171.9 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS75560.1 - 1.5e-18 66.4 37.7 1.7e-18 66.2 25.7 1.3 2 0 0 2 2 2 1 Amino acid permease MFS_1 PF07690.11 ETS75561.1 - 3.8e-39 134.3 28.8 3.8e-39 134.3 20.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS75562.1 - 5.7e-31 107.3 0.1 8.6e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75562.1 - 3.6e-06 26.7 12.5 7.5e-06 25.7 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2597 PF10772.4 ETS75562.1 - 0.0011 18.8 0.0 0.0056 16.5 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2597) Aldo_ket_red PF00248.16 ETS75563.1 - 9e-58 195.3 0.0 1.1e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 ETS75564.1 - 5.4e-48 163.0 0.0 8.9e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS75564.1 - 2.2e-38 131.7 0.1 3.3e-37 127.8 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 ETS75564.1 - 3.2e-15 56.2 0.0 6.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS75564.1 - 1.8e-09 37.7 0.0 2.9e-08 33.8 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site SKI PF01202.17 ETS75564.1 - 2.5e-09 37.1 0.0 1.9e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.1 ETS75564.1 - 3.6e-09 37.4 0.0 1.2e-08 35.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS75564.1 - 9.2e-09 35.3 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS75564.1 - 6.8e-07 29.6 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain 3Beta_HSD PF01073.14 ETS75564.1 - 3e-06 26.1 0.0 9.8e-06 24.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS75564.1 - 1.2e-05 25.2 0.7 6.2e-05 22.9 0.5 2.3 1 1 0 1 1 1 1 short chain dehydrogenase AAA_16 PF13191.1 ETS75564.1 - 0.0004 20.4 0.0 0.0013 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain KR PF08659.5 ETS75564.1 - 0.00041 20.0 0.3 0.0015 18.2 0.2 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS75564.1 - 0.0012 18.9 0.1 0.057 13.4 0.1 2.5 1 1 0 1 1 1 1 NADH(P)-binding APS_kinase PF01583.15 ETS75564.1 - 0.0033 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ANF_receptor PF01094.23 ETS75564.1 - 0.0074 15.1 0.0 0.4 9.4 0.0 2.3 2 0 0 2 2 2 1 Receptor family ligand binding region Zeta_toxin PF06414.7 ETS75564.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Polysacc_synt_2 PF02719.10 ETS75564.1 - 0.013 14.3 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 ETS75564.1 - 0.014 15.6 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PRK PF00485.13 ETS75564.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 ETS75564.1 - 0.032 13.7 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS75564.1 - 0.035 14.3 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 ETS75564.1 - 0.038 13.7 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 ETS75564.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DapB_N PF01113.15 ETS75564.1 - 0.045 13.6 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 ETS75564.1 - 0.048 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 NmrA-like family KAP_NTPase PF07693.9 ETS75564.1 - 0.049 12.6 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 ETS75564.1 - 0.052 13.6 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS75564.1 - 0.053 13.2 0.1 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 ETS75564.1 - 0.062 13.2 0.1 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA12 PF10443.4 ETS75564.1 - 0.066 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Arch_ATPase PF01637.13 ETS75564.1 - 0.07 12.8 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 ETS75564.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_PrkA PF08298.6 ETS75564.1 - 0.087 11.5 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain IBB PF01749.15 ETS75564.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Importin beta binding domain TIP49 PF06068.8 ETS75564.1 - 0.18 10.4 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2183 PF09949.4 ETS75565.1 - 3.7e-32 110.2 0.0 1.6e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 ETS75565.1 - 0.005 16.4 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DEAD PF00270.24 ETS75566.1 - 1.6e-45 154.6 0.5 5.5e-45 152.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS75566.1 - 7.4e-26 89.8 0.0 1.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 ETS75566.1 - 1.1e-05 24.0 0.1 1.1e-05 24.0 0.0 3.0 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) Fungal_trans PF04082.13 ETS75567.1 - 8.3e-33 113.3 0.0 1.4e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75567.1 - 6.1e-06 26.0 10.3 6.1e-06 26.0 7.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 ETS75568.1 - 0.0018 16.7 0.0 0.0023 16.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family Transferase PF02458.10 ETS75569.1 - 7.3e-16 57.6 0.0 9.1e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 ETS75569.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Condensation domain Chitin_bind_3 PF03067.10 ETS75570.1 - 0.00018 21.8 0.0 0.00018 21.8 0.0 1.8 2 1 0 2 2 2 1 Chitin binding domain Glyco_hydro_61 PF03443.9 ETS75570.1 - 0.00091 19.0 0.2 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Tyrosinase PF00264.15 ETS75571.1 - 3.5e-33 115.6 0.3 5.3e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3593 PF12159.3 ETS75573.1 - 0.61 9.9 3.9 1.2 8.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) HEAT_2 PF13646.1 ETS75574.1 - 5.3e-20 71.4 6.9 4.8e-05 23.5 0.1 6.4 5 1 0 6 6 6 4 HEAT repeats NACHT PF05729.7 ETS75574.1 - 5.9e-19 68.3 1.1 1.5e-15 57.2 0.0 3.1 3 0 0 3 3 3 2 NACHT domain HEAT PF02985.17 ETS75574.1 - 4.9e-07 29.2 4.2 0.0028 17.5 0.0 6.8 9 0 0 9 9 9 1 HEAT repeat AAA_22 PF13401.1 ETS75574.1 - 1.8e-06 28.1 0.3 0.0092 16.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain HEAT_EZ PF13513.1 ETS75574.1 - 6.6e-05 23.2 5.7 1.4 9.4 0.0 6.9 7 1 0 7 7 7 1 HEAT-like repeat AAA_17 PF13207.1 ETS75574.1 - 0.00072 20.3 0.0 0.011 16.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETS75574.1 - 0.00083 18.2 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 ETS75574.1 - 0.00087 19.1 0.2 0.0044 16.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 ETS75574.1 - 0.0037 17.5 0.0 0.16 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 ETS75574.1 - 0.0054 15.4 0.0 0.011 14.4 0.0 1.5 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.1 ETS75574.1 - 0.034 14.1 0.2 0.45 10.4 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 ETS75574.1 - 0.086 12.5 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 ETS75574.1 - 0.093 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 ETS75574.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Glyco_hydro_2_N PF02837.13 ETS75576.1 - 1.1e-07 31.5 0.0 2.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain FAD_binding_4 PF01565.18 ETS75577.1 - 1.1e-17 63.8 1.2 1.6e-17 63.2 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS75577.1 - 7.9e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 ETS75578.1 - 4.3e-44 150.7 0.0 6.2e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS75579.1 - 1.2e-42 145.9 47.3 1.2e-42 145.9 32.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS75579.1 - 1.9e-13 49.5 11.0 3e-13 48.8 7.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS75579.1 - 2.4e-11 42.8 13.7 2.4e-11 42.8 9.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_4 PF01565.18 ETS75580.1 - 1.5e-25 89.2 0.1 2.3e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS75580.1 - 0.045 13.6 0.4 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 Berberine and berberine like Death PF00531.17 ETS75580.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Death domain Ank_2 PF12796.2 ETS75581.1 - 5.1e-22 78.0 0.1 4.9e-09 36.4 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75581.1 - 6.4e-12 44.6 2.8 0.5 10.2 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 ETS75581.1 - 5.1e-11 42.7 1.4 0.45 11.0 0.0 5.4 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75581.1 - 4.3e-10 38.8 0.3 0.86 10.0 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 ETS75581.1 - 2e-05 24.6 3.9 0.89 9.8 0.2 5.0 3 2 4 7 7 7 4 Ankyrin repeats (many copies) DUF4145 PF13643.1 ETS75581.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) SGS PF05002.10 ETS75581.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 SGS domain Abhydrolase_3 PF07859.8 ETS75582.1 - 2.3e-26 92.6 2.1 7.5e-22 77.9 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS75582.1 - 1.8e-11 43.6 0.1 8.2e-07 28.4 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS75582.1 - 7.4e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75582.1 - 4.7e-10 39.7 3.8 6.3e-10 39.3 2.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS75582.1 - 1.7e-06 27.1 0.0 2.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS75582.1 - 0.001 17.9 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 ETS75582.1 - 0.0013 18.2 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 ETS75582.1 - 0.012 14.9 0.3 0.046 13.0 0.1 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.23 ETS75582.1 - 0.035 12.8 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_4 PF08386.5 ETS75582.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pro_isomerase PF00160.16 ETS75584.1 - 4e-41 140.8 1.3 4.8e-41 140.5 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M43 PF05572.8 ETS75585.1 - 4.7e-12 45.7 0.6 9.4e-12 44.7 0.1 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 ETS75585.1 - 1.1e-06 28.3 0.4 3.8e-06 26.5 0.3 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETS75585.1 - 1.1e-06 28.8 0.5 2.7e-06 27.5 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 ETS75585.1 - 7.2e-05 22.7 0.5 0.00017 21.6 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 ETS75585.1 - 0.0012 19.3 0.4 0.0082 16.6 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 ETS75585.1 - 0.0032 17.2 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 ETS75585.1 - 0.02 13.7 0.4 0.034 13.0 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.11 ETS75585.1 - 0.037 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DHDPS PF00701.17 ETS75586.1 - 2.5e-32 111.6 0.0 3.2e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MRP-S33 PF08293.6 ETS75586.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 DUF818 PF05677.7 ETS75586.1 - 0.076 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Sulfate_tra_GLY PF13792.1 ETS75586.1 - 0.12 12.0 0.0 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif MR_MLE_C PF13378.1 ETS75587.1 - 1.4e-33 115.2 0.0 2.9e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 ETS75587.1 - 3.2e-15 56.1 0.0 6.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 ETS75587.1 - 1.8e-10 41.1 0.0 6.1e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Cyclase PF04199.8 ETS75588.1 - 4.7e-15 55.6 0.0 7.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Transposase_mut PF00872.13 ETS75589.1 - 0.077 11.5 0.1 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF2976 PF11190.3 ETS75589.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Pectate_lyase PF03211.8 ETS75590.1 - 3.6e-62 209.5 3.6 4.6e-62 209.2 2.5 1.0 1 0 0 1 1 1 1 Pectate lyase DNA_methylase PF00145.12 ETS75591.1 - 1.3e-31 109.9 0.0 2.6e-31 108.9 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 ETS75591.1 - 9.2e-05 22.1 0.0 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 1 BAH domain DUF155 PF02582.9 ETS75592.1 - 8e-37 126.8 0.1 1.6e-36 125.8 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Sec7 PF01369.15 ETS75594.1 - 1.7e-41 142.0 0.0 4.5e-41 140.6 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 ETS75594.1 - 6.7e-19 68.2 0.0 1.5e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Pyr_redox_3 PF13738.1 ETS75595.1 - 9.7e-18 64.9 0.0 2.5e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS75595.1 - 1.3e-08 34.7 0.0 3.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 ETS75595.1 - 3.6e-08 32.0 0.0 9.1e-07 27.4 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 ETS75595.1 - 0.0035 17.1 0.2 0.064 13.0 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS75595.1 - 0.013 14.4 0.0 0.095 11.6 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lactamase_B PF00753.22 ETS75596.1 - 1.8e-21 76.6 0.7 3.1e-21 75.9 0.5 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS75596.1 - 1.7e-07 30.9 0.1 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain OKR_DC_1_N PF03709.10 ETS75596.1 - 0.16 12.0 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Fungal_trans PF04082.13 ETS75597.1 - 0.00036 19.4 0.8 0.0013 17.6 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Cu-oxidase PF00394.17 ETS75598.1 - 1.6e-34 119.0 0.0 1e-31 110.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS75598.1 - 1.9e-31 108.2 1.1 1.9e-31 108.2 0.8 2.4 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS75598.1 - 1.9e-21 76.0 11.6 2e-20 72.6 1.4 3.3 3 1 0 3 3 3 2 Multicopper oxidase Solute_trans_a PF03619.11 ETS75599.1 - 2.2e-41 141.9 10.6 2.8e-41 141.6 7.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CFEM PF05730.6 ETS75600.1 - 7.2e-11 41.7 4.6 1.1e-10 41.1 3.2 1.3 1 0 0 1 1 1 1 CFEM domain Peptidase_C34 PF05413.6 ETS75600.1 - 0.033 14.2 0.5 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Acyl_transf_3 PF01757.17 ETS75601.1 - 1.5e-22 79.9 29.9 6.7e-22 77.7 20.5 2.1 1 1 0 1 1 1 1 Acyltransferase family Acetyltransf_1 PF00583.19 ETS75602.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_transf_20 PF00982.16 ETS75603.1 - 4.4e-147 490.3 0.0 6.7e-147 489.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETS75603.1 - 1e-76 256.9 0.2 2.3e-76 255.8 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 ETS75603.1 - 0.0099 16.0 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Hydrolase_3 PF08282.7 ETS75603.1 - 0.018 14.6 0.1 0.46 10.0 0.0 2.4 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS75603.1 - 0.027 14.6 0.2 0.57 10.3 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.15 ETS75603.1 - 0.18 11.2 0.0 0.76 9.1 0.0 2.1 2 1 0 2 2 2 0 Glycosyl transferases group 1 MFS_1 PF07690.11 ETS75604.1 - 1.3e-37 129.3 48.6 5.1e-37 127.4 32.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS75604.1 - 2.7e-16 58.8 12.2 2.7e-16 58.8 8.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS75604.1 - 9.4e-11 40.9 11.7 9.4e-11 40.9 8.1 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter DUF2975 PF11188.3 ETS75604.1 - 0.012 15.2 0.3 0.012 15.2 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) ketoacyl-synt PF00109.21 ETS75605.1 - 8.1e-62 208.9 0.2 4.2e-61 206.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS75605.1 - 8.6e-61 206.0 2.2 1.6e-60 205.1 1.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 ETS75605.1 - 1.4e-57 194.3 0.1 5e-57 192.4 0.1 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS75605.1 - 1.9e-55 188.1 0.0 3.4e-55 187.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS75605.1 - 2.1e-45 154.6 1.2 4e-45 153.7 0.0 2.2 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS75605.1 - 2.5e-32 111.2 0.1 6.1e-32 109.9 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS75605.1 - 9.1e-21 74.1 0.0 6.4e-20 71.4 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS75605.1 - 1.5e-20 73.0 0.0 4.6e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 ETS75605.1 - 9.6e-13 47.9 0.0 2.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS75605.1 - 1.7e-11 45.0 0.0 7.3e-11 43.0 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 ETS75605.1 - 1.8e-11 44.0 0.0 6.3e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 ETS75605.1 - 4.9e-11 42.3 0.6 1.4e-10 40.9 0.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 ETS75605.1 - 1.6e-10 41.5 0.0 5.9e-10 39.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75605.1 - 3.6e-09 36.9 0.0 1.3e-08 35.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS75605.1 - 2.1e-07 31.2 0.0 3.6e-05 24.0 0.0 3.5 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 ETS75605.1 - 1.3e-06 28.5 0.2 3.7e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS75605.1 - 0.00069 18.6 1.1 0.0026 16.7 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 ETS75605.1 - 0.019 14.4 0.1 0.38 10.1 0.0 2.7 3 1 0 3 3 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 ETS75605.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 ETS75605.1 - 0.083 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF1996 PF09362.5 ETS75608.1 - 8.3e-56 189.2 0.5 1e-55 189.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sipho_tail PF05709.6 ETS75609.1 - 0.014 14.5 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein DUF4394 PF14339.1 ETS75609.1 - 0.036 13.3 0.2 6.6 5.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4394) p450 PF00067.17 ETS75610.1 - 5.3e-57 193.3 0.0 7.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SurE PF01975.12 ETS75611.1 - 0.071 12.3 0.3 0.069 12.4 0.2 1.1 1 0 0 1 1 1 0 Survival protein SurE ISG65-75 PF11727.3 ETS75611.1 - 0.1 11.5 5.4 0.12 11.3 3.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.8 ETS75611.1 - 0.11 12.9 8.4 0.14 12.5 2.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apo-CIII PF05778.7 ETS75611.1 - 0.59 9.5 2.3 17 4.8 0.3 2.3 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) CsbD PF05532.7 ETS75611.1 - 1.2 8.8 21.2 8.7 6.1 10.6 3.3 2 1 0 2 2 2 0 CsbD-like Pkinase PF00069.20 ETS75612.1 - 5.5e-10 38.8 0.0 1.2e-08 34.4 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75612.1 - 1e-06 28.0 0.0 4.8e-05 22.5 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase UDPGT PF00201.13 ETS75613.1 - 0.0027 16.3 0.0 0.052 12.0 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase ECH PF00378.15 ETS75615.1 - 3.2e-45 154.1 0.1 6.3e-42 143.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Ank_2 PF12796.2 ETS75616.1 - 3.3e-17 62.6 0.0 5.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75616.1 - 8.9e-17 59.9 0.4 7e-11 41.3 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS75616.1 - 1.1e-15 57.3 1.0 1.2e-10 41.3 0.4 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75616.1 - 8.8e-15 53.3 0.0 1.2e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS75616.1 - 1.1e-14 54.4 1.5 4.1e-07 30.3 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.3 ETS75617.1 - 1.8e-07 30.1 1.5 0.00029 19.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75617.1 - 0.0018 18.1 14.6 0.0037 17.1 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS75618.1 - 3.3e-32 111.5 37.1 1.6e-31 109.2 25.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily RNase_H PF00075.19 ETS75619.1 - 4.6e-17 62.5 0.0 5.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETS75619.1 - 0.00044 19.9 0.4 0.058 13.1 0.0 2.4 2 1 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.19 ETS75620.1 - 5.1e-11 43.0 0.0 1.2e-10 41.8 0.0 1.6 1 1 1 2 2 2 1 RNase H RVT_3 PF13456.1 ETS75620.1 - 0.00018 21.2 0.6 0.022 14.5 0.0 2.6 2 1 0 2 2 2 2 Reverse transcriptase-like Kinesin PF00225.18 ETS75621.1 - 4.3e-81 272.2 0.1 6e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 ETS75621.1 - 8.7e-05 22.3 2.8 9.4e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.1 ETS75621.1 - 0.0079 16.3 3.4 0.096 12.8 1.8 2.9 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_7 PF14635.1 ETS75621.1 - 0.011 15.7 0.0 0.074 13.1 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif MerR-DNA-bind PF09278.6 ETS75621.1 - 4.7 7.6 6.6 1.6 9.2 1.1 2.7 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.11 ETS75622.1 - 4.3e-38 130.9 35.3 4.3e-38 130.9 24.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 ETS75624.1 - 1.8e-42 145.3 0.0 2.1e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS75624.1 - 3.2e-07 30.4 0.3 4.6e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS75624.1 - 7.2e-07 29.0 0.1 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS75624.1 - 3.6e-06 26.3 0.4 0.0057 15.8 0.1 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 ETS75624.1 - 8.6e-06 25.1 0.1 0.0068 15.7 0.0 2.4 2 1 1 3 3 3 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 ETS75624.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 ETS75624.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.6 ETS75624.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 ETS75624.1 - 0.0025 16.6 0.2 0.014 14.1 0.1 2.1 2 1 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 ETS75624.1 - 0.0028 16.1 0.1 0.0075 14.7 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 ETS75624.1 - 0.0058 15.9 0.6 0.21 10.8 0.0 2.4 3 0 0 3 3 3 1 Esterase PHB depolymerase Esterase PF00756.15 ETS75624.1 - 0.011 15.1 1.1 0.23 10.8 0.7 2.1 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 ETS75624.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain zf-C2H2_2 PF12756.2 ETS75625.1 - 2.1e-24 85.5 3.7 3.3e-24 84.9 2.6 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 ETS75626.1 - 9.9e-10 38.2 12.2 6.9e-05 22.9 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETS75626.1 - 1.6e-09 37.5 20.2 0.00029 20.9 4.8 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS75626.1 - 4.4e-05 23.5 18.5 0.063 13.6 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger C1_4 PF07975.7 ETS75626.1 - 1.3 9.0 6.2 2.9 7.9 4.3 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain p450 PF00067.17 ETS75628.1 - 1.4e-41 142.5 0.0 1.8e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.14 ETS75630.1 - 4.6e-11 42.5 10.0 4.6e-11 42.5 6.9 1.9 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 ETS75630.1 - 6.5e-06 25.3 1.0 6.5e-06 25.3 0.7 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 ETS75630.1 - 0.006 16.9 4.2 0.013 15.8 2.9 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J Podoplanin PF05808.6 ETS75630.1 - 0.0074 15.8 3.2 0.015 14.8 2.2 1.5 1 0 0 1 1 1 1 Podoplanin Plasmodium_Vir PF05795.6 ETS75630.1 - 0.091 11.9 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nitrate_red_gam PF02665.9 ETS75630.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Ank_2 PF12796.2 ETS75632.1 - 1.6e-34 118.0 0.1 3.7e-12 46.4 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75632.1 - 1.9e-26 90.4 13.3 8.7e-06 25.3 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 ETS75632.1 - 1.3e-25 88.7 12.5 1.5e-08 34.6 0.1 7.0 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75632.1 - 2.6e-21 73.5 5.8 0.0012 18.8 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETS75632.1 - 1.9e-19 69.6 5.4 0.00083 19.8 0.1 7.5 6 2 2 8 8 8 4 Ankyrin repeats (many copies) W2 PF02020.13 ETS75633.1 - 3.9e-18 65.1 2.9 6.3e-18 64.5 0.9 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 ETS75633.1 - 7.5e-09 34.7 6.0 0.00084 18.7 0.2 4.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS75633.1 - 2.9e-08 33.1 0.6 0.0021 17.5 0.1 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 ETS75633.1 - 0.002 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 ETS75633.1 - 0.0053 15.3 0.5 0.021 13.3 0.3 1.8 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.2 ETS75633.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain HSF_DNA-bind PF00447.12 ETS75634.1 - 3.2e-34 117.2 0.8 7.2e-34 116.0 0.6 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 ETS75634.1 - 2.5e-21 75.7 0.2 8.9e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain CENP-Q PF13094.1 ETS75634.1 - 0.0025 17.8 4.9 0.0043 17.1 3.4 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_tail_1 PF01576.14 ETS75634.1 - 0.0063 14.3 2.8 0.0085 13.8 2.0 1.1 1 0 0 1 1 1 1 Myosin tail UBN2_3 PF14244.1 ETS75634.1 - 0.15 11.6 4.1 0.55 9.7 0.7 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF972 PF06156.8 ETS75634.1 - 0.19 12.0 1.8 0.4 11.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.7 ETS75634.1 - 0.37 10.9 3.7 0.67 10.1 2.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF904 PF06005.7 ETS75634.1 - 2.1 8.6 5.2 3.9 7.8 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) COesterase PF00135.23 ETS75635.1 - 2.8e-94 316.7 1.2 1.4e-84 284.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS75635.1 - 5.6e-12 45.6 0.1 8.8e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS75635.1 - 0.0013 18.4 0.3 0.0026 17.5 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family RCR PF12273.3 ETS75636.1 - 0.012 16.1 0.3 0.027 15.0 0.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.7 ETS75636.1 - 0.022 14.6 0.8 0.046 13.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) PepSY_TM_2 PF13703.1 ETS75636.1 - 0.056 13.6 0.8 0.082 13.0 0.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Herpes_gE PF02480.11 ETS75636.1 - 0.064 11.5 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAD_binding_3 PF01494.14 ETS75637.1 - 1.1e-78 264.8 0.1 1.4e-78 264.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS75637.1 - 6.2e-44 149.5 0.0 1.4e-43 148.4 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 ETS75637.1 - 7.8e-07 28.3 0.3 0.0019 17.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS75637.1 - 1.7e-05 24.1 0.8 5.9e-05 22.3 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS75637.1 - 0.0013 17.6 0.4 0.0075 15.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS75637.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETS75637.1 - 0.012 15.5 0.2 0.036 14.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS75637.1 - 0.037 12.8 0.0 3.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 ETS75637.1 - 0.086 11.6 0.1 0.57 8.9 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS75637.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PIP5K PF01504.13 ETS75638.1 - 5.2e-33 114.2 0.0 6.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase OST3_OST6 PF04756.8 ETS75639.1 - 6.3 6.3 9.5 0.61 9.6 2.8 1.9 2 0 0 2 2 2 0 OST3 / OST6 family TPR_10 PF13374.1 ETS75640.1 - 9.3e-57 187.4 18.2 1.1e-08 34.6 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETS75640.1 - 1.6e-50 168.9 16.9 3e-16 59.1 0.6 5.6 3 1 2 5 5 5 5 Tetratricopeptide repeat HET PF06985.6 ETS75640.1 - 2.7e-21 76.2 8.9 1e-20 74.3 0.4 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 ETS75640.1 - 4.7e-14 51.7 0.6 1.1e-05 25.0 0.1 4.7 4 0 0 4 4 4 3 TPR repeat TPR_7 PF13176.1 ETS75640.1 - 9e-12 43.8 9.7 0.041 13.6 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS75640.1 - 9.1e-12 43.9 6.1 0.09 12.7 0.2 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS75640.1 - 4.4e-10 38.9 2.2 0.19 12.0 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS75640.1 - 6.7e-10 39.3 2.2 0.016 15.8 0.0 6.0 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS75640.1 - 2e-07 30.3 6.8 0.16 11.6 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETS75640.1 - 9.6e-07 28.9 0.0 6.5e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS75640.1 - 2e-06 27.9 0.8 1e-05 25.6 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain NB-ARC PF00931.17 ETS75640.1 - 3.3e-06 26.1 0.0 7.4e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 ETS75640.1 - 1.3e-05 25.4 3.7 2.2 8.6 0.2 5.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS75640.1 - 5.7e-05 23.4 6.3 32 5.5 0.0 7.5 6 1 2 8 8 8 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS75640.1 - 0.0053 16.8 8.1 0.18 11.9 0.1 4.5 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 ETS75640.1 - 0.0063 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 ETS75640.1 - 0.01 15.2 0.1 0.055 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS75640.1 - 0.014 16.2 0.0 0.14 12.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_3 PF07720.7 ETS75640.1 - 0.015 15.0 0.1 1.2e+02 2.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS75640.1 - 0.016 15.6 0.0 44 4.9 0.0 4.7 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS75640.1 - 0.022 14.5 6.0 11 6.1 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS75640.1 - 0.11 13.0 4.4 20 5.8 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 ETS75640.1 - 0.12 12.5 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4404 PF14357.1 ETS75640.1 - 0.2 12.0 9.1 11 6.5 0.2 4.7 4 1 2 6 6 5 0 Domain of unknown function (DUF4404) DUF3500 PF12006.3 ETS75641.1 - 1.5e-85 286.9 0.0 1.8e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Pec_lyase_C PF00544.14 ETS75642.1 - 8.7e-15 54.7 2.7 2.2e-14 53.4 1.9 1.6 1 1 0 1 1 1 1 Pectate lyase Methyltransf_2 PF00891.13 ETS75643.1 - 1.5e-27 96.3 0.0 4.5e-27 94.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Amino_oxidase PF01593.19 ETS75644.1 - 5.6e-61 206.9 0.1 8.7e-48 163.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS75644.1 - 2.1e-10 40.4 0.3 6.8e-10 38.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS75644.1 - 1.4e-05 24.2 1.4 0.0046 15.9 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS75644.1 - 2.9e-05 24.2 0.1 9.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS75644.1 - 0.00012 21.0 0.2 0.00023 20.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS75644.1 - 0.00071 19.9 0.2 0.065 13.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS75644.1 - 0.002 18.2 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 ETS75644.1 - 0.0047 16.0 0.4 0.019 14.0 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ETS75644.1 - 0.011 14.9 0.6 0.018 14.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 ETS75644.1 - 0.014 14.5 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 ETS75644.1 - 0.022 14.6 0.1 0.065 13.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS75644.1 - 0.035 13.8 0.3 4.4 7.0 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS75644.1 - 0.041 12.7 1.3 0.062 12.1 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 ETS75644.1 - 0.11 11.4 0.1 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AA_permease_2 PF13520.1 ETS75645.1 - 8.9e-49 166.1 50.1 1.1e-48 165.8 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS75645.1 - 9.1e-22 77.0 43.2 1.2e-21 76.6 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease HALZ PF02183.13 ETS75646.1 - 0.33 10.6 2.1 0.87 9.3 1.5 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.20 ETS75647.1 - 2.6e-29 102.1 0.0 3.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75647.1 - 7.9e-16 57.8 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS75647.1 - 0.035 12.9 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 ETS75647.1 - 0.06 13.0 0.8 1.9 8.1 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 ETS75648.1 - 3.7e-23 82.0 0.0 6.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS75648.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS75648.1 - 0.0078 15.0 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase HET PF06985.6 ETS75649.1 - 4.3e-16 59.3 0.0 7.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 ETS75650.1 - 1.4e-59 201.5 0.1 1.4e-59 201.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Mucin PF01456.12 ETS75650.1 - 0.0023 17.7 24.8 0.0043 16.8 17.2 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.3 ETS75650.1 - 0.023 13.9 21.7 0.025 13.8 15.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PBD PF00786.23 ETS75651.1 - 0.00015 22.1 0.2 0.0012 19.2 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain S1 PF00575.18 ETS75652.1 - 9.3e-90 294.7 42.0 3.1e-13 49.5 0.2 13.3 13 0 0 13 13 13 12 S1 RNA binding domain TPR_14 PF13428.1 ETS75652.1 - 9.8e-06 25.7 0.3 0.59 10.9 0.0 5.2 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS75652.1 - 5.8e-05 23.3 2.1 0.58 10.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 ETS75652.1 - 0.00013 21.8 13.0 0.0006 19.6 0.1 4.3 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) S1_2 PF13509.1 ETS75652.1 - 0.0011 18.8 0.2 3.4 7.6 0.0 4.2 4 0 0 4 4 4 2 S1 domain TPR_11 PF13414.1 ETS75652.1 - 0.04 13.5 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Nop14 PF04147.7 ETS75652.1 - 0.28 9.0 31.2 0.71 7.7 21.6 1.6 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETS75652.1 - 4 5.8 34.9 0.0034 15.9 14.8 2.5 2 1 0 2 2 2 0 Daxx Family TMEM171 PF15471.1 ETS75653.1 - 1.1 7.9 4.3 0.32 9.7 0.8 1.6 2 0 0 2 2 2 0 Transmembrane protein family 171 Fmp27 PF10344.4 ETS75654.1 - 2.1e-223 743.7 0.0 3e-223 743.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 ETS75654.1 - 1.2e-173 578.1 3.9 1.2e-173 578.1 2.7 2.0 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 ETS75654.1 - 1.7e-155 518.0 0.5 3.2e-155 517.1 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 ETS75654.1 - 8.2e-55 185.0 0.0 2e-54 183.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 ETS75654.1 - 3.8e-49 166.4 0.1 8.5e-49 165.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 ETS75654.1 - 1.2e-34 118.8 0.0 4.9e-34 116.8 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Glyco_hydro_16 PF00722.16 ETS75655.1 - 2e-09 36.9 0.9 3.2e-09 36.3 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.21 ETS75656.1 - 8.3e-08 31.9 4.2 2.1e-07 30.6 2.9 1.7 1 0 0 1 1 1 1 WW domain Selenoprotein_S PF06936.6 ETS75656.1 - 4.2 6.8 8.7 4.8 6.6 3.3 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1517 PF07466.6 ETS75657.1 - 0.0015 17.5 3.8 0.0024 16.8 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) SKG6 PF08693.5 ETS75657.1 - 0.0083 15.4 3.1 0.0083 15.4 2.1 2.4 2 1 1 3 3 3 1 Transmembrane alpha-helix domain Cytomega_TRL10 PF06084.6 ETS75657.1 - 0.03 14.1 0.2 0.074 12.8 0.1 1.7 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF1180 PF06679.7 ETS75657.1 - 0.057 13.3 1.8 0.14 12.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) YajC PF02699.10 ETS75657.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit P12 PF12669.2 ETS75657.1 - 0.18 12.0 0.5 0.18 12.0 0.3 3.4 2 1 0 2 2 2 0 Virus attachment protein p12 family TMEM154 PF15102.1 ETS75657.1 - 1 9.0 6.7 3.4 7.3 4.6 1.8 1 1 0 1 1 1 0 TMEM154 protein family Proteasome PF00227.21 ETS75658.1 - 1e-56 191.2 0.2 1.5e-56 190.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS75658.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.7 ETS75659.1 - 1e-13 51.2 20.0 1.3e-13 50.9 13.9 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 ETS75659.1 - 0.033 13.9 12.4 0.37 10.6 5.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 ETS75659.1 - 0.83 9.7 13.4 1.1 9.3 3.7 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain DUF3797 PF12677.2 ETS75659.1 - 1.9 8.1 0.0 1.9 8.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Cytochrome_C7 PF14522.1 ETS75659.1 - 2.6 7.7 14.0 4 7.1 9.7 1.3 1 0 0 1 1 1 0 Cytochrome c7 zf-RING_3 PF14369.1 ETS75659.1 - 7.8 6.5 14.0 0.79 9.7 4.9 2.6 1 1 2 3 3 3 0 zinc-finger Zn-ribbon_8 PF09723.5 ETS75659.1 - 8.6 6.4 19.6 1.2 9.1 5.8 2.8 3 0 0 3 3 3 0 Zinc ribbon domain Macoilin PF09726.4 ETS75660.1 - 0.16 10.2 21.0 0.19 9.9 14.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF966 PF06136.8 ETS75660.1 - 0.81 9.0 11.7 1 8.6 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Rifin_STEVOR PF02009.11 ETS75660.1 - 1.6 8.3 4.9 1.8 8.0 3.4 1.1 1 0 0 1 1 1 0 Rifin/stevor family Zn_clus PF00172.13 ETS75661.1 - 3.3e-05 23.7 11.6 5.9e-05 22.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 ETS75662.1 - 4.1e-40 137.6 0.1 6.2e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 ETS75664.1 - 6.7e-29 99.5 0.1 8.3e-29 99.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 ETS75664.1 - 0.0052 17.1 0.1 0.0063 16.8 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein zf-rbx1 PF12678.2 ETS75665.1 - 3.8e-35 119.8 13.5 4.7e-35 119.5 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS75665.1 - 3.8e-17 61.9 9.8 4.9e-17 61.5 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 ETS75665.1 - 5.1e-07 29.4 11.9 3.4e-06 26.7 8.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS75665.1 - 0.0013 18.3 11.5 0.023 14.3 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS75665.1 - 0.0023 17.5 9.3 0.34 10.6 6.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS75665.1 - 0.046 13.7 12.5 0.051 13.6 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS75665.1 - 0.43 10.3 11.6 4.3 7.1 8.0 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 ETS75665.1 - 0.87 9.5 9.4 4.8 7.2 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 ETS75665.1 - 1.6 8.7 10.3 5.3 7.0 7.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 ETS75665.1 - 1.7 8.3 7.1 1.9 8.2 1.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 ETS75665.1 - 1.9 8.6 11.0 1.3e+02 2.8 7.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PNRC PF15365.1 ETS75666.1 - 1.4 8.9 26.3 0.081 12.9 10.3 4.5 4 2 0 4 4 4 0 Proline-rich nuclear receptor coactivator Axin_b-cat_bind PF08833.5 ETS75666.1 - 6.2 6.6 15.8 1.1 8.9 0.1 4.5 4 0 0 4 4 4 0 Axin beta-catenin binding domain p450 PF00067.17 ETS75667.1 - 2.4e-45 154.9 0.0 3.2e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mg-por_mtran_C PF07109.6 ETS75667.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Tyr-DNA_phospho PF06087.7 ETS75668.1 - 3.8e-72 243.3 0.0 6.2e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 ETS75668.1 - 3.2e-05 23.6 0.0 0.00099 18.8 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 ETS75668.1 - 0.0014 18.0 2.9 0.0084 15.6 0.2 4.2 5 0 0 5 5 5 2 Ubiquitin interaction motif NOA36 PF06524.7 ETS75668.1 - 1.3 8.1 8.0 2.2 7.4 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Gti1_Pac2 PF09729.4 ETS75669.1 - 1.3e-58 197.6 0.8 2e-58 197.0 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 ETS75670.1 - 3.8e-16 59.2 3.7 8.1e-16 58.1 2.6 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 ETS75671.1 - 7.9e-159 528.7 0.0 9.7e-159 528.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 ETS75671.1 - 9.6e-16 57.6 0.0 7.9e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 ETS75671.1 - 4.5e-07 29.9 0.2 1.2e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS75671.1 - 8e-07 28.4 0.2 1.4e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS75671.1 - 0.0009 18.1 4.5 0.00094 18.1 1.3 2.3 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 ETS75671.1 - 0.0016 17.3 0.8 0.57 9.0 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS75671.1 - 0.019 13.4 0.6 0.14 10.6 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 ETS75671.1 - 0.024 14.2 0.4 0.042 13.4 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 ETS75671.1 - 0.049 13.8 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 ETS75671.1 - 0.13 12.6 0.2 0.33 11.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS75671.1 - 0.14 11.2 0.2 0.25 10.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Sec1 PF00995.18 ETS75672.1 - 6.8e-153 510.2 0.0 7.8e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 ETS75672.1 - 0.049 13.5 0.1 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain DUF2404 PF10296.4 ETS75673.1 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Peptidase_M24 PF00557.19 ETS75675.1 - 7.9e-45 152.9 0.2 1.1e-44 152.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS75675.1 - 2.1e-27 96.2 0.1 3.6e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain FUN14 PF04930.10 ETS75676.1 - 0.00023 21.3 2.6 0.00023 21.3 1.8 1.8 2 1 0 2 2 2 1 FUN14 family Histone PF00125.19 ETS75677.1 - 2.1e-31 107.8 0.3 2.9e-31 107.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETS75677.1 - 9.3e-05 22.5 0.1 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETS75677.1 - 0.0058 16.6 0.1 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 ETS75677.1 - 0.01 15.0 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 ETS75678.1 - 3.5e-48 163.7 3.5 4e-48 163.5 2.4 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.9 ETS75679.1 - 2.1e-47 160.9 0.3 2.5e-47 160.7 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 ETS75679.1 - 7.8e-09 34.9 0.1 1.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 ETS75679.1 - 5.7e-06 26.0 0.0 7.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 ETS75679.1 - 0.00018 20.9 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Cupin adh_short PF00106.20 ETS75680.1 - 2.5e-23 82.8 0.0 3.8e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75680.1 - 1.7e-13 50.5 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS75680.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 ETS75680.1 - 1.3e-05 25.1 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 ETS75680.1 - 4.1e-05 22.4 0.0 6.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS75680.1 - 0.00034 19.6 0.0 0.00046 19.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS75680.1 - 0.00061 19.8 0.0 0.001 19.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS75680.1 - 0.0015 17.4 0.0 0.003 16.4 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 ETS75680.1 - 0.003 16.8 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 ETS75680.1 - 0.052 13.4 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UAA PF08449.6 ETS75681.1 - 1.4e-11 43.8 17.9 2.1e-11 43.3 12.4 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 ETS75681.1 - 7.1e-09 35.4 8.5 7.1e-09 35.4 5.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS75681.1 - 0.094 12.7 28.0 0.27 11.2 6.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family Tad PF13400.1 ETS75681.1 - 0.33 11.0 5.8 0.45 10.5 2.1 2.6 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Peptidase_A24 PF01478.13 ETS75681.1 - 7.5 6.7 16.7 0.53 10.4 3.7 3.7 2 2 0 2 2 2 0 Type IV leader peptidase family MBOAT PF03062.14 ETS75682.1 - 5.7e-50 170.2 7.3 5.7e-50 170.2 5.0 1.9 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 ETS75682.1 - 2.5 7.8 12.7 0.15 11.7 2.7 2.6 2 0 0 2 2 2 0 PAP2 superfamily DUF2371 PF10177.4 ETS75683.1 - 0.12 12.3 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Abi PF02517.11 ETS75684.1 - 4e-13 49.3 14.6 2.1e-12 47.0 8.9 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity tRNA-synt_1b PF00579.20 ETS75685.1 - 8.6e-72 241.7 0.0 1.1e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LktC PF06261.6 ETS75685.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Ribosomal_S10 PF00338.17 ETS75686.1 - 1.6e-22 79.1 0.0 2.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e JAB PF01398.16 ETS75687.1 - 3.7e-30 104.0 0.1 5.7e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 ETS75687.1 - 3.9e-07 29.6 0.0 7.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain tRNA-synt_1c PF00749.16 ETS75688.1 - 9.2e-95 316.8 0.0 1.2e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PSD1 PF07587.6 ETS75688.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) DnaJ PF00226.26 ETS75689.1 - 2.2e-25 88.1 5.7 2.3e-25 88.1 2.2 2.2 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 ETS75689.1 - 1.7e-21 75.9 0.7 3.2e-19 68.5 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETS75689.1 - 6.1e-14 51.8 18.9 1e-13 51.0 13.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 ETS75689.1 - 0.063 12.9 6.8 0.76 9.4 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Val_tRNA-synt_C PF10458.4 ETS75689.1 - 0.11 12.6 0.9 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Cytochrom_c3_2 PF14537.1 ETS75689.1 - 0.38 11.1 5.8 0.84 10.0 4.0 1.6 1 0 0 1 1 1 0 Cytochrome c3 DUF1356 PF07092.7 ETS75689.1 - 0.9 8.6 5.1 1.2 8.2 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-CHY PF05495.7 ETS75689.1 - 1.4 9.1 6.5 1.4 9.1 0.4 2.3 2 0 0 2 2 2 0 CHY zinc finger Ribosomal_L32e PF01655.13 ETS75690.1 - 6.7e-50 167.7 2.5 6.7e-50 167.7 1.7 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 Pectate_lyase PF03211.8 ETS75691.1 - 6.2e-64 215.3 2.6 7.7e-64 215.0 1.8 1.0 1 0 0 1 1 1 1 Pectate lyase Pyr_redox_2 PF07992.9 ETS75692.1 - 1.4e-38 132.8 0.0 3.1e-38 131.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS75692.1 - 3e-13 49.9 0.0 3.5e-11 43.3 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS75692.1 - 3.3e-09 37.1 0.0 0.0047 17.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M16_C PF05193.16 ETS75693.1 - 6.3e-50 169.4 0.0 2.1e-49 167.6 0.0 1.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS75693.1 - 1.8e-42 144.5 0.0 1.5e-41 141.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tannase PF07519.6 ETS75696.1 - 1.3e-131 439.5 2.8 1.7e-131 439.2 1.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF3129 PF11327.3 ETS75697.1 - 2.4e-17 63.3 16.3 2.4e-17 63.3 11.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) TPR_12 PF13424.1 ETS75698.1 - 1.9e-26 91.7 20.3 6.4e-10 38.8 0.1 5.8 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETS75698.1 - 3.6e-23 80.7 23.7 0.0044 16.9 0.5 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETS75698.1 - 9.2e-19 65.7 13.2 0.16 11.8 0.1 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS75698.1 - 9.9e-16 57.8 17.6 0.0002 21.5 0.1 7.3 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS75698.1 - 1.3e-15 55.9 7.9 0.97 9.5 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS75698.1 - 3.5e-14 52.6 15.8 0.00021 21.3 0.3 6.2 2 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS75698.1 - 4.2e-13 49.5 14.4 0.086 13.5 0.1 7.8 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETS75698.1 - 1.7e-12 46.7 15.4 1.4 9.7 0.1 8.5 8 0 0 8 8 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 ETS75698.1 - 3e-12 45.9 0.0 5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 ETS75698.1 - 3.2e-12 45.3 0.0 0.17 11.7 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS75698.1 - 3.5e-12 45.8 11.3 0.0019 17.7 0.0 6.5 2 1 5 8 8 8 6 TPR repeat TPR_1 PF00515.23 ETS75698.1 - 9.4e-11 40.8 0.3 3.1 7.5 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS75698.1 - 3.2e-10 39.7 5.7 0.61 10.6 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 ETS75698.1 - 1.7e-09 36.9 0.2 5.8 7.1 0.0 7.0 6 0 0 6 6 6 0 PPR repeat TPR_20 PF14561.1 ETS75698.1 - 1.9e-06 27.8 18.3 0.36 10.9 0.3 6.4 2 1 5 7 7 6 3 Tetratricopeptide repeat PPR_1 PF12854.2 ETS75698.1 - 1.4e-05 24.5 0.9 12 5.4 0.0 5.2 5 0 0 5 5 5 0 PPR repeat TPR_4 PF07721.9 ETS75698.1 - 6.2e-05 23.0 8.0 0.5 10.9 0.2 6.4 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 ETS75698.1 - 7.8e-05 22.8 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.1 ETS75698.1 - 0.00043 20.2 4.7 50 4.4 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_2 PF13041.1 ETS75698.1 - 0.00092 19.1 0.1 26 4.9 0.0 5.4 6 0 0 6 6 6 0 PPR repeat family NACHT PF05729.7 ETS75698.1 - 0.0011 18.7 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PPR_3 PF13812.1 ETS75698.1 - 0.0037 17.4 0.7 1.3e+02 3.2 0.0 5.8 6 0 0 6 6 5 0 Pentatricopeptide repeat domain PNP_UDP_1 PF01048.15 ETS75698.1 - 0.011 14.6 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphorylase superfamily DUF4248 PF14053.1 ETS75698.1 - 0.039 13.5 1.1 3.1 7.4 0.0 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF4248) Paf67 PF10255.4 ETS75698.1 - 0.06 12.2 0.2 4.2 6.1 0.0 3.3 2 2 2 4 4 4 0 RNA polymerase I-associated factor PAF67 DUF627 PF04781.7 ETS75698.1 - 0.69 9.5 4.3 7 6.3 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF627) Fic PF02661.13 ETS75699.1 - 1.3e-20 73.8 0.0 3.4e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family WD40 PF00400.27 ETS75700.1 - 5.5e-51 168.7 22.8 4.8e-11 42.0 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 ETS75700.1 - 9e-12 44.5 2.0 2.1e-11 43.3 1.4 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 ETS75700.1 - 3.7e-09 35.2 12.6 0.0098 14.0 0.2 6.2 2 1 5 7 7 7 5 Nucleoporin Nup120/160 F-box PF00646.28 ETS75700.1 - 6.3e-06 25.6 3.1 1.5e-05 24.5 2.1 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 ETS75700.1 - 7.1e-05 22.3 5.0 0.008 15.6 0.6 2.5 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 ETS75700.1 - 0.001 18.8 0.1 2.8 7.7 0.0 3.5 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 ETS75700.1 - 0.012 14.3 0.1 0.073 11.8 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.1 ETS75700.1 - 0.18 12.1 13.2 9.5 6.6 0.0 6.3 6 2 1 7 7 7 0 PQQ-like domain Zip PF02535.17 ETS75701.1 - 1.1e-38 132.9 0.0 2.3e-37 128.7 0.0 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.4 ETS75702.1 - 1.3e-42 145.6 0.0 2.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Glyco_hydro_12 PF01670.11 ETS75702.1 - 0.054 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 Acetyltransf_7 PF13508.1 ETS75702.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS75702.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS75702.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P5CR_dimer PF14748.1 ETS75703.1 - 1e-32 112.3 2.9 1.9e-32 111.4 2.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 ETS75703.1 - 7.2e-14 51.9 2.2 6.7e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 ETS75703.1 - 0.026 14.2 5.4 1.4 8.6 3.7 3.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CTK3 PF12243.3 ETS75704.1 - 3.5e-54 182.2 0.0 5.7e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 ETS75704.1 - 3.9e-18 65.2 9.3 1.1e-17 63.7 6.4 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Ribosomal_L12 PF00542.14 ETS75705.1 - 5e-20 71.2 5.8 4.8e-19 68.1 2.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 ETS75705.1 - 0.0074 16.6 4.1 0.0074 16.6 2.8 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein AAA_5 PF07728.9 ETS75706.1 - 2.8e-128 422.3 0.0 5.9e-21 74.6 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETS75706.1 - 6.4e-30 103.4 0.0 7.6e-11 41.7 0.0 6.6 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 ETS75706.1 - 1.6e-28 99.5 0.2 4.9e-05 23.5 0.0 7.6 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS75706.1 - 8.4e-28 97.6 0.0 0.00016 22.4 0.0 7.5 6 0 0 6 6 6 5 AAA domain AAA_33 PF13671.1 ETS75706.1 - 6e-26 91.0 0.0 0.0006 19.7 0.0 7.6 6 1 0 6 6 6 6 AAA domain AAA_16 PF13191.1 ETS75706.1 - 7.8e-25 87.9 31.9 2.5e-06 27.6 1.2 9.7 9 0 0 9 9 7 5 AAA ATPase domain AAA_22 PF13401.1 ETS75706.1 - 1.1e-22 80.5 1.7 0.0037 17.4 0.0 8.3 7 1 0 7 7 6 6 AAA domain Sigma54_activ_2 PF14532.1 ETS75706.1 - 3.5e-22 78.9 1.1 0.00069 19.6 0.0 8.5 7 1 1 8 8 7 3 Sigma-54 interaction domain AAA_18 PF13238.1 ETS75706.1 - 9e-22 77.7 0.1 0.0016 18.7 0.0 8.4 7 0 0 7 7 7 3 AAA domain Sigma54_activat PF00158.21 ETS75706.1 - 1.7e-19 69.9 0.1 0.027 13.9 0.0 7.0 7 0 0 7 7 7 4 Sigma-54 interaction domain AAA_14 PF13173.1 ETS75706.1 - 2.2e-19 69.6 0.0 0.0008 19.3 0.0 8.0 8 0 0 8 8 7 2 AAA domain T2SE PF00437.15 ETS75706.1 - 2.5e-16 59.3 2.2 0.021 13.7 0.0 6.6 7 0 0 7 7 6 4 Type II/IV secretion system protein RNA_helicase PF00910.17 ETS75706.1 - 2.2e-13 50.3 3.1 0.068 13.3 0.0 7.3 7 0 0 7 7 7 2 RNA helicase UPF0079 PF02367.12 ETS75706.1 - 2.6e-13 49.6 4.7 0.0042 16.6 0.0 6.0 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 ETS75706.1 - 9.3e-13 47.7 1.1 0.012 14.7 0.0 6.0 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 ETS75706.1 - 1.4e-12 47.5 7.2 0.47 10.0 0.0 6.6 6 0 0 6 6 5 4 NACHT domain Zeta_toxin PF06414.7 ETS75706.1 - 1.7e-12 46.8 1.3 0.27 10.3 0.0 7.0 6 0 0 6 6 6 2 Zeta toxin AAA_19 PF13245.1 ETS75706.1 - 1.8e-12 46.7 13.8 0.023 14.4 0.0 7.0 7 0 0 7 7 6 3 Part of AAA domain MobB PF03205.9 ETS75706.1 - 3.4e-12 46.2 2.1 0.65 9.6 0.0 7.6 7 0 0 7 7 7 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 ETS75706.1 - 3.7e-12 46.7 13.3 0.013 15.7 0.0 7.9 8 0 0 8 8 6 4 ABC transporter AAA_29 PF13555.1 ETS75706.1 - 1.3e-11 43.7 1.2 0.32 10.5 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain Arch_ATPase PF01637.13 ETS75706.1 - 2e-11 44.0 0.0 0.015 15.0 0.0 6.7 6 0 0 6 6 6 1 Archaeal ATPase AAA_25 PF13481.1 ETS75706.1 - 3e-11 43.0 2.5 0.77 9.1 0.0 6.2 6 0 0 6 6 5 3 AAA domain DUF258 PF03193.11 ETS75706.1 - 8.4e-11 41.3 7.2 0.62 9.2 0.1 5.9 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_28 PF13521.1 ETS75706.1 - 1.6e-10 41.2 6.3 0.21 11.5 0.0 7.4 7 0 0 7 7 6 1 AAA domain Mg_chelatase PF01078.16 ETS75706.1 - 2.3e-09 36.7 5.4 2.4 7.2 0.0 8.2 9 0 0 9 9 8 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 ETS75706.1 - 1.6e-08 34.1 1.0 0.037 13.5 0.0 6.3 7 0 0 7 7 7 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 ETS75706.1 - 8.4e-08 31.8 1.3 0.18 11.2 0.0 5.9 6 0 0 6 6 6 1 IstB-like ATP binding protein Miro PF08477.8 ETS75706.1 - 1.1e-07 32.3 5.3 6.9 7.1 0.0 7.1 7 0 0 7 7 6 0 Miro-like protein NTPase_1 PF03266.10 ETS75706.1 - 1.5e-07 31.3 5.6 0.83 9.3 0.0 6.3 6 0 0 6 6 6 2 NTPase SRP54 PF00448.17 ETS75706.1 - 6.9e-07 28.9 4.5 0.94 8.8 0.1 5.3 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 ETS75706.1 - 8.3e-07 28.7 0.1 0.31 10.5 0.0 5.5 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 ETS75706.1 - 9.8e-07 27.8 4.1 0.085 11.5 0.0 5.5 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein KTI12 PF08433.5 ETS75706.1 - 2e-06 27.2 0.0 0.12 11.5 0.0 5.0 6 0 0 6 6 5 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 ETS75706.1 - 6.5e-06 26.0 0.2 23 4.9 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_7 PF12775.2 ETS75706.1 - 1.3e-05 24.4 1.8 0.23 10.5 0.0 4.1 5 0 0 5 5 5 2 P-loop containing dynein motor region D3 TIP49 PF06068.8 ETS75706.1 - 3.5e-05 22.6 1.9 3.7 6.1 0.0 5.0 6 0 0 6 6 6 0 TIP49 C-terminus cobW PF02492.14 ETS75706.1 - 9.8e-05 21.8 7.1 2.6 7.4 0.0 5.7 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 ETS75706.1 - 0.0011 18.9 0.7 9.1 6.1 0.0 5.0 4 0 0 4 4 4 0 Shikimate kinase NB-ARC PF00931.17 ETS75706.1 - 0.0011 17.9 3.5 13 4.5 0.0 5.4 6 0 0 6 6 6 0 NB-ARC domain AAA_6 PF12774.2 ETS75706.1 - 0.0016 17.9 0.0 4.6 6.6 0.0 4.6 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 ATP_bind_1 PF03029.12 ETS75706.1 - 0.0025 17.3 9.3 8.6 5.8 0.0 6.3 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 ETS75706.1 - 0.016 15.2 0.2 43 3.9 0.0 5.1 5 1 0 5 5 5 0 AAA domain KaiC PF06745.8 ETS75706.1 - 0.027 13.5 0.0 19 4.2 0.0 4.6 4 0 0 4 4 4 0 KaiC PhoH PF02562.11 ETS75706.1 - 0.039 13.1 0.5 9.1 5.4 0.0 4.0 5 0 0 5 5 3 0 PhoH-like protein ArgK PF03308.11 ETS75706.1 - 0.17 10.6 2.8 12 4.5 0.0 3.8 4 0 0 4 4 4 0 ArgK protein APS_kinase PF01583.15 ETS75706.1 - 0.19 11.3 2.1 11 5.6 0.0 4.1 5 0 0 5 5 3 0 Adenylylsulphate kinase NMO PF03060.10 ETS75707.1 - 3.4e-39 134.9 11.2 1.2e-38 133.0 7.8 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 ETS75707.1 - 3.1e-09 36.1 5.3 5.5e-09 35.3 3.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS75707.1 - 4.7e-08 32.3 2.5 0.0035 16.3 2.0 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS75707.1 - 3.1e-05 23.0 3.7 5.1e-05 22.3 2.6 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Clr5 PF14420.1 ETS75708.1 - 4.9e-17 61.5 0.1 1.3e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain zf-RING_2 PF13639.1 ETS75710.1 - 2.6e-08 33.5 0.2 2.6e-08 33.5 0.2 4.0 3 1 0 3 3 2 1 Ring finger domain PHD PF00628.24 ETS75710.1 - 1.4e-07 31.0 11.2 1.4e-07 31.0 7.8 2.7 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 ETS75710.1 - 6.1e-05 22.6 1.4 6.1e-05 22.6 1.0 3.7 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS75710.1 - 0.00012 21.6 0.4 0.00012 21.6 0.3 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS75710.1 - 0.00013 21.9 15.2 0.00045 20.2 3.2 3.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS75710.1 - 0.00015 21.3 0.1 0.00015 21.3 0.1 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS75710.1 - 0.00046 20.1 0.6 0.00046 20.1 0.4 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS75710.1 - 0.00096 18.9 0.2 0.00096 18.9 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 ETS75710.1 - 0.038 13.1 0.0 0.038 13.1 0.0 3.2 3 0 0 3 3 3 0 Rtf2 RING-finger GcpE PF04551.9 ETS75710.1 - 0.056 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 GcpE protein CotJB PF12652.2 ETS75710.1 - 0.092 12.8 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 CotJB protein PHD_2 PF13831.1 ETS75710.1 - 3.9 6.8 14.2 0.057 12.7 4.1 2.2 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 ETS75710.1 - 8.6 6.4 10.8 0.28 11.1 0.2 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain Ribosomal_L37ae PF01780.14 ETS75711.1 - 6.1e-40 134.9 9.1 6.8e-40 134.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Elf1 PF05129.8 ETS75711.1 - 0.0035 17.0 0.3 0.005 16.5 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 ETS75711.1 - 0.013 15.2 3.4 0.02 14.6 2.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ETS75711.1 - 0.018 14.6 1.3 0.025 14.2 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 ETS75711.1 - 0.031 14.5 0.8 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.5 ETS75711.1 - 0.076 12.4 3.5 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain CarbpepA_inh PF02977.10 ETS75711.1 - 0.23 11.0 2.2 0.84 9.2 1.6 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-BED PF02892.10 ETS75711.1 - 0.59 9.9 6.9 2.4 8.0 0.6 2.4 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.10 ETS75711.1 - 2.6 7.6 6.7 0.69 9.5 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Saccharop_dh PF03435.13 ETS75712.1 - 1e-20 74.0 0.1 1.3e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS75712.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS75712.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF155 PF02582.9 ETS75713.1 - 8.5e-54 182.0 0.4 1.3e-53 181.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 ETS75714.1 - 1.3e-09 38.1 1.5 3.1e-09 36.9 1.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS75714.1 - 0.0013 19.0 3.5 0.0028 17.9 1.9 2.0 1 1 0 1 1 1 1 HMG-box domain bZIP_1 PF00170.16 ETS75714.1 - 0.025 14.5 6.4 0.19 11.7 2.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 ETS75714.1 - 1.6 9.1 5.8 0.65 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3987 PF13148.1 ETS75714.1 - 2.6 6.5 7.8 3.1 6.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Cpn60_TCP1 PF00118.19 ETS75715.1 - 2.3e-138 461.8 3.5 2.6e-138 461.6 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.15 ETS75715.1 - 0.034 13.6 0.2 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 EAL domain HAD PF12710.2 ETS75715.1 - 0.049 13.7 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HET PF06985.6 ETS75716.1 - 6.6e-27 94.3 0.2 1.5e-26 93.1 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS75717.1 - 7.7e-17 61.7 2.9 5e-15 55.8 3.2 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GspH PF12019.3 ETS75717.1 - 0.014 15.5 0.0 0.65 10.1 0.0 2.5 2 0 0 2 2 2 0 Type II transport protein GspH HET PF06985.6 ETS75718.1 - 2.2e-33 115.3 1.9 4.1e-33 114.4 0.7 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS75719.1 - 2.8e-52 177.8 0.0 3.5e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.5 ETS75720.1 - 2.6e-56 190.1 0.2 4.5e-56 189.3 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS75720.1 - 4.4e-42 143.8 1.3 9.4e-42 142.7 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 ETS75720.1 - 3e-15 55.9 0.0 6.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 ETS75720.1 - 1.7e-10 40.9 0.3 6.5e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 ETS75720.1 - 3.1e-10 41.0 0.0 6.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.6 ETS75722.1 - 1.5e-31 109.4 0.0 4.3e-31 107.9 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PH_10 PF15411.1 ETS75724.1 - 9.8e-27 93.4 0.1 1.6e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 ETS75724.1 - 2.1e-10 40.5 0.0 1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 ETS75724.1 - 4.5e-09 36.2 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 ETS75724.1 - 7.9e-08 32.0 5.5 1.5e-07 31.1 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS75724.1 - 0.00058 19.4 2.3 0.001 18.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS75724.1 - 0.00095 18.8 5.1 0.0016 18.1 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS75724.1 - 0.0054 16.8 1.0 0.011 15.8 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETS75724.1 - 0.0055 16.6 4.7 0.01 15.8 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS75724.1 - 0.017 14.7 4.5 0.031 13.9 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 ETS75724.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger NAD_synthase PF02540.12 ETS75724.1 - 0.089 11.6 0.2 1 8.1 0.0 2.1 2 0 0 2 2 2 0 NAD synthase zf-RING-like PF08746.6 ETS75724.1 - 0.3 11.1 4.1 0.54 10.3 2.8 1.4 1 0 0 1 1 1 0 RING-like domain 2OG-FeII_Oxy PF03171.15 ETS75725.1 - 2.8e-10 40.3 0.0 4.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS75725.1 - 9.7e-08 32.5 0.0 2.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_L18e PF00828.14 ETS75726.1 - 8.2e-21 74.7 0.3 1.4e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 WSC PF01822.14 ETS75729.1 - 4.1e-12 45.8 10.1 4.1e-12 45.8 7.0 2.2 2 0 0 2 2 2 1 WSC domain Med3 PF11593.3 ETS75729.1 - 1.2 8.3 17.6 1.4 8.0 12.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 ETS75729.1 - 5.5 4.7 13.3 5.8 4.6 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sel1 PF08238.7 ETS75730.1 - 0.0041 17.7 0.0 0.016 15.8 0.0 2.1 1 0 0 1 1 1 1 Sel1 repeat TPR_14 PF13428.1 ETS75730.1 - 0.098 13.3 1.2 16 6.5 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.6 ETS75731.1 - 4.2e-07 30.1 0.4 4.2e-07 30.1 0.3 4.9 2 1 0 2 2 2 1 U3 snoRNA associated FAD_binding_3 PF01494.14 ETS75732.1 - 3.4e-19 69.1 0.6 1.6e-09 37.3 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS75732.1 - 3e-06 27.1 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS75732.1 - 0.009 14.9 0.0 0.22 10.3 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS75732.1 - 0.016 15.5 0.1 0.28 11.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS75732.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Propep_M14 PF02244.11 ETS75732.1 - 0.12 12.0 0.2 13 5.5 0.0 2.8 3 0 0 3 3 3 0 Carboxypeptidase activation peptide Glyco_hydro_3 PF00933.16 ETS75733.1 - 2.9e-49 167.6 0.0 4.3e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS75733.1 - 1.1e-45 155.8 0.0 7e-45 153.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS75733.1 - 3e-25 87.9 0.0 5.2e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PX PF00787.19 ETS75734.1 - 4.1e-17 61.9 0.0 8.6e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF605 PF04652.11 ETS75734.1 - 0.078 12.3 9.2 0.1 12.0 6.4 1.2 1 0 0 1 1 1 0 Vta1 like Cullin_binding PF03556.10 ETS75735.1 - 5.1e-30 104.0 2.2 8.3e-30 103.3 1.5 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 ETS75735.1 - 4.7e-08 32.4 0.0 9.7e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UPF0270 PF06794.7 ETS75735.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Ribosomal_S6 PF01250.12 ETS75736.1 - 1.4e-08 34.4 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 COX5B PF01215.14 ETS75738.1 - 2.3e-37 127.7 0.0 3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 ETS75738.1 - 0.018 14.5 0.4 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NUDIX PF00293.23 ETS75739.1 - 5.1e-16 58.5 0.0 8.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 ETS75739.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain Asp PF00026.18 ETS75740.1 - 2e-57 194.8 2.6 2.7e-57 194.4 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS75740.1 - 8.9e-07 29.0 0.3 8.9e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS75740.1 - 1.7 9.1 6.5 2.2 8.8 0.0 3.7 4 1 0 4 4 4 0 Aspartyl protease NAD_binding_1 PF00175.16 ETS75741.1 - 1.1e-12 48.4 0.0 2.6e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 ETS75741.1 - 8.7e-10 38.9 0.1 3.1e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 ETS75741.1 - 1.3e-08 34.8 0.0 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 ETS75741.1 - 5.3e-05 22.9 0.1 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 ETS75741.1 - 0.00016 21.6 0.2 0.0062 16.4 0.1 3.0 2 1 1 3 3 3 1 Ferric reductase NAD binding domain NmrA PF05368.8 ETS75742.1 - 2.5e-20 72.7 0.0 3.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS75742.1 - 1e-15 58.2 0.1 1.8e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS75742.1 - 0.038 14.2 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MIP PF00230.15 ETS75744.1 - 9.8e-51 172.3 15.5 1.2e-50 172.0 10.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein C2 PF00168.25 ETS75746.1 - 1.1e-14 54.0 0.1 1.9e-11 43.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain NUDIX PF00293.23 ETS75748.1 - 0.00054 19.5 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_16 PF00722.16 ETS75749.1 - 3.8e-44 150.1 4.3 5.9e-44 149.5 2.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 ETS75749.1 - 0.025 14.5 12.4 0.074 13.0 8.6 1.7 1 0 0 1 1 1 0 Chitin recognition protein WAP PF00095.16 ETS75749.1 - 1.2 9.1 11.7 0.1 12.5 3.7 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' NAD_binding_10 PF13460.1 ETS75750.1 - 4.5e-13 49.6 0.0 1.5e-07 31.5 0.0 2.7 1 1 2 3 3 3 2 NADH(P)-binding NmrA PF05368.8 ETS75750.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MMR_HSR1 PF01926.18 ETS75751.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 ETS75751.1 - 7.2e-06 25.2 2.5 3.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 ETS75751.1 - 0.0025 17.0 0.2 0.011 14.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 ETS75751.1 - 0.0039 16.0 1.1 0.0043 15.9 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 ETS75751.1 - 0.0057 15.9 0.0 0.022 14.0 0.0 2.0 1 1 1 2 2 2 1 Ferrous iron transport protein B DUF4225 PF13988.1 ETS75751.1 - 0.011 15.2 0.6 0.011 15.2 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4225) Dynamin_N PF00350.18 ETS75751.1 - 0.016 15.0 9.8 0.48 10.2 0.0 3.4 2 2 1 3 3 2 0 Dynamin family Miro PF08477.8 ETS75751.1 - 0.023 15.2 0.6 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 ETS75751.1 - 0.027 14.0 0.5 0.058 12.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GBP PF02263.14 ETS75751.1 - 0.034 13.2 0.0 0.094 11.7 0.0 1.7 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Septin PF00735.13 ETS75751.1 - 0.034 13.1 0.0 0.034 13.1 0.0 2.1 2 0 0 2 2 2 0 Septin DUF87 PF01935.12 ETS75751.1 - 0.037 13.8 0.7 0.037 13.8 0.5 2.6 2 1 1 3 3 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 ETS75751.1 - 0.051 13.0 0.1 0.051 13.0 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 ETS75751.1 - 0.059 12.8 0.5 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 ETS75751.1 - 0.077 12.8 1.0 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS75751.1 - 0.093 13.0 1.8 0.25 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 ETS75751.1 - 0.11 12.1 1.7 0.56 9.9 0.3 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3040 PF11239.3 ETS75751.1 - 0.15 12.0 3.2 14 5.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2277 PF10041.4 ETS75751.1 - 0.17 11.8 1.5 0.68 9.9 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) ABC_tran PF00005.22 ETS75751.1 - 0.22 11.7 7.9 3.2 8.0 5.4 2.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 ETS75751.1 - 0.25 11.3 7.5 7.2 6.5 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 ETS75751.1 - 0.46 11.3 0.0 0.46 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 ETS75751.1 - 0.5 9.8 4.9 0.33 10.4 0.2 2.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 ETS75751.1 - 0.65 9.4 3.6 2.4 7.5 0.4 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS75752.1 - 6e-06 26.2 0.1 3e-05 23.9 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase PQQ_2 PF13360.1 ETS75752.1 - 4.9e-05 22.9 0.0 0.0016 17.9 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain Septin PF00735.13 ETS75752.1 - 6.8e-05 22.0 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 ETS75752.1 - 0.00099 18.3 0.0 0.0024 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 ETS75752.1 - 0.055 12.9 0.2 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 ETS75752.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter PQQ PF01011.16 ETS75752.1 - 0.26 10.8 4.2 21 4.8 0.0 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat Dynamin_N PF00350.18 ETS75752.1 - 0.94 9.2 11.3 0.87 9.3 0.0 3.3 2 2 1 3 3 3 0 Dynamin family DUF87 PF01935.12 ETS75752.1 - 3 7.6 9.1 0.94 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Lactonase PF10282.4 ETS75753.1 - 1.7e-48 165.4 0.1 2.2e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 ETS75753.1 - 0.092 12.6 0.0 0.41 10.5 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat OHCU_decarbox PF09349.5 ETS75756.1 - 3.1e-40 138.0 0.7 5.7e-40 137.2 0.5 1.4 1 1 0 1 1 1 1 OHCU decarboxylase RBM39linker PF15519.1 ETS75756.1 - 0.19 12.0 1.0 5.7 7.3 0.0 2.9 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Inhibitor_Mig-6 PF11555.3 ETS75756.1 - 0.24 11.8 4.6 0.55 10.6 3.2 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Prp19 PF08606.6 ETS75757.1 - 3.9e-33 113.0 1.2 8.3e-33 111.9 0.8 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 ETS75757.1 - 6.9e-11 41.5 0.4 0.0041 16.9 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS75757.1 - 0.00076 19.0 1.9 0.036 13.5 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 ETS75757.1 - 0.00082 19.1 0.0 0.67 9.6 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 ETS75757.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 ETS75757.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 ETS75758.1 - 0.0011 18.6 3.2 0.0026 17.4 2.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS75758.1 - 0.011 15.6 1.5 0.011 15.6 1.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS75758.1 - 0.072 12.7 5.7 0.33 10.6 4.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS75758.1 - 0.089 12.6 2.3 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.11 ETS75759.1 - 3.2e-47 160.9 30.3 3.2e-47 160.9 21.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS75759.1 - 0.00028 19.2 1.9 0.0004 18.7 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 ETS75759.1 - 0.02 12.9 0.8 0.051 11.6 0.6 1.7 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Thioredoxin PF00085.15 ETS75760.1 - 3e-11 42.9 0.0 7.5e-10 38.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS75760.1 - 0.0093 16.1 2.0 0.054 13.6 1.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS75760.1 - 0.21 11.7 1.0 0.59 10.2 0.3 2.0 2 1 0 2 2 2 0 Thioredoxin-like RicinB_lectin_2 PF14200.1 ETS75761.1 - 4.3e-18 65.6 0.1 1.3e-13 51.2 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETS75761.1 - 0.0097 15.9 0.0 0.061 13.3 0.0 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Peroxidase_2 PF01328.12 ETS75762.1 - 8.2e-40 136.4 0.1 1.1e-39 136.0 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.3 ETS75763.1 - 0.0023 16.6 4.0 0.0023 16.6 2.8 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 ETS75764.1 - 6.1e-13 48.4 0.0 5.6e-10 38.7 0.0 2.4 1 1 1 2 2 2 2 Dioxygenase DUF1399 PF07173.7 ETS75765.1 - 1.1e-23 84.0 5.7 1.6e-16 60.8 0.5 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Dioxygenase_C PF00775.16 ETS75766.1 - 1.2e-10 40.9 0.1 2.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 ETS75767.1 - 3.2e-30 105.9 6.1 4.3e-30 105.5 4.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.16 ETS75768.1 - 3.6e-08 32.8 0.0 6.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase TPR_10 PF13374.1 ETS75768.1 - 0.065 13.1 0.5 0.16 11.9 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.2 ETS75769.1 - 1.2e-69 230.6 5.6 1.6e-16 60.3 0.0 9.6 5 4 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS75769.1 - 5.4e-44 143.7 19.1 0.00033 20.5 0.0 17.4 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.25 ETS75769.1 - 9.3e-43 141.9 38.5 1.9e-06 27.3 0.0 15.7 17 0 0 17 17 17 10 Ankyrin repeat Ank_4 PF13637.1 ETS75769.1 - 1.9e-40 136.5 14.1 5.3e-09 36.3 0.0 12.0 12 3 1 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS75769.1 - 2.6e-35 119.6 16.7 0.00032 20.8 0.0 13.8 10 3 5 15 15 15 10 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS75769.1 - 2.9e-15 55.8 4.9 6.1e-15 54.8 3.4 1.6 1 0 0 1 1 1 1 Clr5 domain GFO_IDH_MocA PF01408.17 ETS75772.1 - 2.4e-19 70.0 0.1 5.7e-19 68.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 ETS75772.1 - 0.019 15.3 0.1 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2306 PF10067.4 ETS75773.1 - 2.6e-17 62.8 5.4 2.6e-17 62.8 3.8 2.2 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) DUF998 PF06197.8 ETS75773.1 - 0.00034 19.9 7.5 0.00034 19.9 5.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF420 PF04238.7 ETS75773.1 - 0.22 11.4 2.8 4 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) PepSY_TM_2 PF13703.1 ETS75773.1 - 6.1 7.0 12.2 5.2 7.3 3.0 3.1 1 1 2 3 3 3 0 PepSY-associated TM helix Aldedh PF00171.17 ETS75774.1 - 7.8e-139 462.9 0.0 9.4e-139 462.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DLH PF01738.13 ETS75775.1 - 2.1e-19 69.6 0.0 8.1e-19 67.7 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 ETS75775.1 - 7.9e-06 25.9 0.1 0.0019 18.1 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS75775.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS75775.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3712 PF12505.3 ETS75776.1 - 1.1e-20 73.9 0.1 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF4083 PF13314.1 ETS75776.1 - 1.1 9.2 3.6 2.2 8.1 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) CRAL_TRIO PF00650.15 ETS75777.1 - 1.3e-38 131.9 0.0 4.9e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS75777.1 - 1.2e-10 41.3 2.3 2.4e-10 40.3 0.2 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 ETS75777.1 - 5.7e-08 32.7 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2693 PF10902.3 ETS75777.1 - 0.17 11.7 0.9 0.38 10.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Pyr_redox_3 PF13738.1 ETS75778.1 - 5.9e-25 88.5 0.0 9.6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS75778.1 - 6.6e-14 51.0 0.0 4.3e-12 45.0 0.0 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS75778.1 - 1.2e-09 38.0 0.0 1.4e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS75778.1 - 3e-08 33.0 0.0 2.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 ETS75778.1 - 1.1e-07 31.1 0.3 1.1e-05 24.4 0.0 3.0 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS75778.1 - 4.6e-06 25.7 0.1 5.6e-05 22.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS75778.1 - 0.00011 21.2 0.6 0.0054 15.6 0.0 3.1 4 0 0 4 4 4 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS75778.1 - 0.0004 20.3 0.1 0.065 13.1 0.1 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS75778.1 - 0.0034 16.3 0.1 0.048 12.5 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS75778.1 - 0.0037 16.4 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS75778.1 - 0.014 15.7 0.0 6.1 7.3 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS75778.1 - 0.018 14.8 0.2 3.1 7.5 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 ETS75778.1 - 0.026 13.6 0.1 0.049 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 ETS75778.1 - 0.079 11.8 0.1 0.16 10.8 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS75778.1 - 0.14 12.2 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 ETS75778.1 - 0.16 10.4 0.4 0.38 9.1 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF150 PF02576.12 ETS75778.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 Mqo PF06039.10 ETS75778.1 - 0.19 9.8 0.0 1.4 7.0 0.0 2.2 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Abhydrolase_3 PF07859.8 ETS75779.1 - 3.6e-25 88.7 0.0 4.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS75779.1 - 1.5e-09 37.0 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS75779.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 ETS75780.1 - 2.8e-30 105.4 0.1 5.7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75780.1 - 2.2e-10 40.4 0.4 5.9e-10 39.1 0.1 1.8 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS75780.1 - 1.4e-09 38.1 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 ETS75780.1 - 6.5e-05 21.7 0.1 9.7e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS75780.1 - 0.00035 20.0 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 ETS75780.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS75780.1 - 0.0038 17.2 0.1 0.0082 16.1 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS75780.1 - 0.025 13.7 1.6 0.036 13.2 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.13 ETS75781.1 - 1.5e-09 37.5 9.3 3.8e-09 36.2 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS75782.1 - 3.4e-74 250.0 0.0 4.5e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3786 PF12654.2 ETS75782.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) ParA PF10609.4 ETS75782.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ParA/MinD ATPase like PGAP1 PF07819.8 ETS75783.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF835 PF05763.7 ETS75783.1 - 0.062 12.8 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF835) HET PF06985.6 ETS75784.1 - 2e-22 79.8 2.9 3.8e-22 78.9 2.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLT_beta PF02258.11 ETS75784.1 - 0.15 11.9 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Shiga-like toxin beta subunit adh_short PF00106.20 ETS75785.1 - 1.2e-19 70.8 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS75785.1 - 6.2e-10 39.0 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS75785.1 - 3.9e-05 23.1 0.0 6.6e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 ETS75785.1 - 0.0052 16.8 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 ETS75785.1 - 0.053 12.4 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS75785.1 - 0.064 12.1 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein DUF3425 PF11905.3 ETS75786.1 - 1.7e-30 105.6 0.5 2.8e-30 104.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_4 PF01565.18 ETS75788.1 - 1.2e-16 60.4 3.2 3.7e-07 29.6 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 ETS75788.1 - 9.1e-11 41.5 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS75788.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fungal_trans_2 PF11951.3 ETS75789.1 - 5.2e-16 58.2 0.5 7.2e-16 57.7 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGAP1 PF07819.8 ETS75790.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS75790.1 - 5.9e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS75790.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETS75790.1 - 0.0012 18.1 0.0 0.0045 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 ETS75790.1 - 0.0028 17.2 0.1 0.008 15.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS75790.1 - 0.003 17.1 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 ETS75790.1 - 0.0067 16.1 0.2 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 ETS75790.1 - 0.033 13.2 0.0 5.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 ETS75790.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS75790.1 - 0.084 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.10 ETS75790.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Aldedh PF00171.17 ETS75791.1 - 1.1e-122 409.7 2.3 1.2e-122 409.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lantibiotic_a PF14867.1 ETS75791.1 - 0.073 12.3 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 Lantibiotic alpha DUF1487 PF07368.6 ETS75791.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Aldedh PF00171.17 ETS75792.1 - 7.5e-26 90.4 0.1 8.5e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.19 ETS75793.1 - 0.0052 15.7 0.9 1.5 7.6 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS75793.1 - 0.013 15.2 3.2 2.5 7.8 0.2 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS75793.1 - 0.037 14.0 0.1 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75793.1 - 0.046 13.5 0.0 0.082 12.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS75793.1 - 0.051 12.6 4.1 0.82 8.6 2.9 2.7 1 1 0 1 1 1 0 FAD binding domain PHZA_PHZB PF03284.8 ETS75794.1 - 4.7e-19 68.0 0.0 6e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B Cupin_3 PF05899.7 ETS75795.1 - 1e-07 31.2 0.1 1.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 ETS75795.1 - 1.5e-07 31.0 0.1 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.6 ETS75795.1 - 0.0019 17.6 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS75795.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF4098 PF13345.1 ETS75795.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) KduI PF04962.7 ETS75795.1 - 0.095 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Fungal_trans_2 PF11951.3 ETS75796.1 - 1.7e-08 33.5 1.8 1.9e-08 33.3 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLAC1 PF03595.12 ETS75797.1 - 6.5e-59 199.2 33.5 7.4e-59 199.0 23.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Sugar_tr PF00083.19 ETS75798.1 - 5.2e-73 246.1 19.4 6.2e-73 245.8 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75798.1 - 5.5e-34 117.4 43.9 2.2e-28 98.9 18.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_39 PF01229.12 ETS75799.1 - 2.3e-05 23.0 0.2 3.3e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 DUF1680 PF07944.7 ETS75800.1 - 2.9e-116 388.8 0.4 3.6e-116 388.4 0.3 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Fungal_trans PF04082.13 ETS75801.1 - 5.5e-08 32.0 4.1 1e-07 31.1 2.2 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75801.1 - 1.3e-05 24.9 10.7 3.3e-05 23.7 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 ETS75801.1 - 7.7e-05 22.7 1.3 7.7e-05 22.7 0.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS75801.1 - 0.00076 19.6 15.2 0.011 16.0 4.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS75801.1 - 0.0053 17.0 15.8 0.058 13.7 4.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type NAD_binding_10 PF13460.1 ETS75802.1 - 8.3e-10 38.9 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS75802.1 - 3.5e-08 33.1 0.0 6.2e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS75802.1 - 2.7e-05 23.2 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 ETS75802.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS75802.1 - 0.00026 20.9 0.0 0.00078 19.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 ETS75802.1 - 0.029 13.2 0.0 0.095 11.5 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETS75802.1 - 0.05 12.3 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETS75802.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 KR domain EthD PF07110.6 ETS75803.1 - 7.3e-23 81.3 0.5 8.6e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 EthD domain NAD_binding_2 PF03446.10 ETS75804.1 - 2e-35 122.0 0.1 4.3e-35 120.9 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS75804.1 - 2.2e-15 56.8 3.2 3.5e-15 56.1 2.2 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 ETS75804.1 - 1.6e-05 25.2 0.0 4.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS75804.1 - 0.00029 20.0 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_15 PF01793.11 ETS75805.1 - 5.1e-131 436.5 0.3 6.6e-131 436.1 0.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ILVD_EDD PF00920.16 ETS75806.1 - 3.9e-199 662.3 0.1 4.5e-199 662.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Myb_DNA-bind_6 PF13921.1 ETS75807.1 - 3.6e-05 23.7 0.2 0.0023 18.0 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS75807.1 - 0.014 15.4 0.4 0.27 11.3 0.3 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS75808.1 - 2.2e-12 46.8 0.7 1.3e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS75808.1 - 2.5e-12 46.6 1.8 2.4e-06 27.4 0.3 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain WD40 PF00400.27 ETS75810.1 - 1e-25 88.6 9.3 2.9e-10 39.5 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETS75810.1 - 1e-16 60.5 0.0 2.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Chs3p PF12271.3 ETS75812.1 - 2.1e-138 460.2 14.8 2.5e-138 460.0 10.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 ETS75812.1 - 3.7 7.5 11.3 0.19 11.6 3.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) DUF4604 PF15377.1 ETS75813.1 - 2.2e-24 86.4 16.6 3.1e-24 85.9 11.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Glyco_transf_8 PF01501.15 ETS75814.1 - 1.8e-23 83.1 0.0 2.7e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 ETS75814.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 1 0 1 1 1 0 Mannosyltransferase putative DHQ_synthase PF01761.15 ETS75815.1 - 7.3e-54 182.4 0.0 1e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 ETS75815.1 - 3.5e-11 42.9 0.0 5.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 ETS75815.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.3 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase Methyltransf_24 PF13578.1 ETS75816.1 - 3e-13 50.5 0.0 5.7e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ETS75816.1 - 3.4e-12 45.8 0.0 4.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.7 ETS75816.1 - 0.00056 19.2 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_21 PF05050.7 ETS75816.1 - 0.0044 16.9 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain ATP-grasp_4 PF13535.1 ETS75817.1 - 3.6e-06 26.8 0.0 1.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS75817.1 - 1.7e-05 23.7 0.0 0.0001 21.1 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Aldo_ket_red PF00248.16 ETS75818.1 - 1e-49 168.9 0.0 1.2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 ETS75819.1 - 1.9e-35 121.9 0.0 3.3e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS75819.1 - 1.2e-23 83.2 0.0 1.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 ETS75819.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS75819.1 - 2e-05 24.7 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 ETS75819.1 - 0.0066 15.1 0.0 0.024 13.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 ETS75819.1 - 0.016 15.5 0.0 0.057 13.7 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 ETS75819.1 - 0.054 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 ETS75819.1 - 0.13 12.1 1.6 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase WD40 PF00400.27 ETS75820.1 - 2.1e-35 119.3 10.1 1.1e-09 37.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-NADH-PPase PF09297.6 ETS75820.1 - 0.027 13.9 1.5 0.1 12.1 1.0 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 ETS75820.1 - 0.047 13.4 1.5 0.096 12.5 1.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.1 ETS75820.1 - 0.12 12.0 4.1 0.17 11.5 1.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal Thioredoxin PF00085.15 ETS75821.1 - 1.2e-26 92.4 0.0 1.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 ETS75821.1 - 4.3e-07 29.8 0.4 8.2e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 ETS75821.1 - 1.1e-06 28.6 0.0 1.6e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS75821.1 - 2.6e-06 27.5 0.1 2.3e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 ETS75821.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family TrbC_Ftype PF09673.5 ETS75821.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_9 PF14595.1 ETS75821.1 - 0.009 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 ETS75821.1 - 0.063 12.8 0.2 0.076 12.5 0.1 1.5 1 1 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 ETS75821.1 - 0.075 13.0 0.0 0.37 10.8 0.0 2.1 1 1 1 2 2 2 0 Glutaredoxin HyaE PF07449.6 ETS75821.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 ETS75821.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF836 PF05768.9 ETS75821.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Amidoligase_2 PF12224.3 ETS75822.1 - 4.6e-17 62.4 0.0 7e-17 61.8 0.0 1.3 1 1 0 1 1 1 1 Putative amidoligase enzyme SapA PF02199.10 ETS75822.1 - 0.045 13.5 1.3 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 Saposin A-type domain eRF1_1 PF03463.10 ETS75823.1 - 1.9e-39 134.2 0.1 4.9e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 ETS75823.1 - 2e-23 83.1 0.0 3.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ETS75823.1 - 1.2e-19 70.6 0.0 2.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 ETS75824.1 - 7.5e-50 169.3 0.0 1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 ETS75825.1 - 4.4e-82 276.0 22.0 5.1e-82 275.8 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75825.1 - 2.1e-18 66.1 27.7 2.1e-18 66.1 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS75825.1 - 8.8e-05 21.0 32.2 0.00042 18.8 2.1 3.9 2 2 2 4 4 4 2 MFS/sugar transport protein Orbi_VP6 PF01516.11 ETS75826.1 - 0.083 11.9 1.4 0.15 11.1 0.9 1.4 1 1 0 1 1 1 0 Orbivirus helicase VP6 Epimerase PF01370.16 ETS75827.1 - 2.3e-09 37.0 0.0 3.3e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS75827.1 - 5.9e-06 26.3 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS75827.1 - 0.00021 20.5 0.0 0.0014 17.9 0.0 2.2 1 1 2 3 3 3 1 NmrA-like family 3Beta_HSD PF01073.14 ETS75827.1 - 0.00024 19.8 0.0 0.00042 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS75827.1 - 0.00056 19.8 0.1 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 ETS75827.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 ETS75827.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 ETS75827.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 ETS75827.1 - 0.028 13.3 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Rnf-Nqr PF02508.9 ETS75827.1 - 0.036 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Cys_Met_Meta_PP PF01053.15 ETS75827.1 - 0.079 11.2 0.0 0.17 10.1 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme KR PF08659.5 ETS75827.1 - 0.12 12.0 0.1 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 KR domain RNA_pol_3_Rpc31 PF11705.3 ETS75828.1 - 1.6e-33 116.6 11.7 2.2e-33 116.1 8.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 ETS75828.1 - 0.00065 19.6 4.8 0.00075 19.4 3.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2201_N PF13203.1 ETS75828.1 - 0.38 9.8 3.8 0.57 9.2 2.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Cwf_Cwc_15 PF04889.7 ETS75828.1 - 1.1 8.8 14.8 1.8 8.1 10.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gly-rich_Ago1 PF12764.2 ETS75828.1 - 3 8.5 5.4 4.8 7.8 3.2 1.6 1 1 0 1 1 1 0 Glycine-rich region of argonaut AAA PF00004.24 ETS75830.1 - 1.9e-16 60.4 0.6 7.5e-14 52.0 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS75830.1 - 0.00012 21.7 0.1 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS75830.1 - 0.00072 20.3 1.9 0.0053 17.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS75830.1 - 0.0025 17.9 3.5 0.045 13.9 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_5 PF07728.9 ETS75830.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS75830.1 - 0.061 13.2 3.8 0.084 12.8 0.2 3.1 4 1 0 4 4 4 0 AAA ATPase domain SOBP PF15279.1 ETS75830.1 - 2.9 8.1 11.2 5.9 7.1 7.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PKD_channel PF08016.7 ETS75831.1 - 3.3e-06 25.7 18.1 7.8e-05 21.2 12.6 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 ETS75831.1 - 5.9e-05 22.4 26.4 0.027 13.6 18.3 2.4 1 1 0 1 1 1 1 Ion transport protein Ly49 PF08391.5 ETS75831.1 - 0.088 12.9 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF843 PF05814.6 ETS75831.1 - 0.79 9.5 7.2 0.75 9.6 0.3 3.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Sugar_tr PF00083.19 ETS75832.1 - 4.1e-39 134.4 18.2 5.9e-39 133.9 12.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75832.1 - 1.3e-33 116.1 22.0 8.5e-27 93.7 5.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 ETS75832.1 - 0.002 16.6 19.6 0.034 12.6 4.6 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like DUF791 PF05631.9 ETS75832.1 - 0.0089 14.7 8.4 0.019 13.7 0.5 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF791) DUF4131 PF13567.1 ETS75832.1 - 0.033 13.5 2.2 0.26 10.6 0.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Macro PF01661.16 ETS75833.1 - 2.6e-35 120.8 0.0 4.9e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Macro domain Stc1 PF12898.2 ETS75834.1 - 0.04 13.9 7.4 2.2 8.3 0.4 2.7 2 0 0 2 2 2 0 Stc1 domain Elf1 PF05129.8 ETS75834.1 - 0.093 12.4 7.0 2.3 7.9 1.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 ETS75834.1 - 0.31 11.3 4.9 3.1 8.1 0.2 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-TFIIB PF13453.1 ETS75834.1 - 1.6 8.0 11.4 0.14 11.4 1.3 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger XPA_N PF01286.13 ETS75834.1 - 3.2 7.4 7.1 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 XPA protein N-terminal DUF2387 PF09526.5 ETS75834.1 - 7.6 6.5 12.7 2.5 8.0 1.2 3.4 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.1 ETS75834.1 - 9.2 5.6 11.1 14 5.0 1.1 3.0 2 2 0 2 2 2 0 zinc-ribbon domain Cyt-b5 PF00173.23 ETS75835.1 - 1.1e-22 79.6 0.1 1.9e-08 33.9 0.0 4.7 4 0 0 4 4 4 4 Cytochrome b5-like Heme/Steroid binding domain ADH_N PF08240.7 ETS75836.1 - 3.8e-24 84.5 5.0 5.9e-24 83.9 3.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS75836.1 - 4.7e-17 61.7 0.0 7.6e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS75836.1 - 1.6e-08 35.5 0.0 3.2e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS75836.1 - 0.022 13.9 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS75836.1 - 0.063 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Haem_bd PF14376.1 ETS75836.1 - 0.19 11.3 0.2 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Haem-binding domain zf-DHHC PF01529.15 ETS75837.1 - 2.7e-12 46.4 0.4 2.7e-12 46.4 0.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase RNase_T PF00929.19 ETS75839.1 - 4.3e-26 92.1 0.0 6.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 ETS75839.1 - 0.0047 16.4 0.0 0.022 14.2 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF2638 PF10937.3 ETS75841.1 - 1.8 9.6 9.4 0.39 11.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Sec3_C PF09763.4 ETS75841.1 - 2.2 6.3 4.7 2.5 6.1 3.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DLIC PF05783.6 ETS75841.1 - 5.5 5.5 7.6 7.5 5.0 5.2 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) PMSI1 PF15322.1 ETS75841.1 - 6.5 5.7 9.8 7.9 5.4 6.8 1.3 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF566 PF04484.7 ETS75841.1 - 8.1 5.8 10.7 8.5 5.7 7.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) PPR_2 PF13041.1 ETS75842.1 - 5.4e-54 179.9 7.3 2e-09 37.2 0.0 14.1 10 4 5 15 15 15 10 PPR repeat family PPR PF01535.15 ETS75842.1 - 3e-29 98.9 17.8 0.00034 20.3 0.0 13.8 14 1 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 ETS75842.1 - 3.4e-28 96.8 0.2 4.8e-08 32.3 0.0 10.3 11 0 0 11 11 11 6 PPR repeat PPR_3 PF13812.1 ETS75842.1 - 1.2e-27 93.8 34.8 0.00041 20.4 0.0 17.0 18 1 1 19 19 19 7 Pentatricopeptide repeat domain RPM2 PF08579.6 ETS75842.1 - 1.7e-05 24.9 0.1 0.0035 17.4 0.0 3.9 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 ETS75842.1 - 0.17 11.2 0.0 6.1 6.2 0.0 3.3 2 2 2 4 4 4 0 Mitochondrial ATPase expression TPR_7 PF13176.1 ETS75842.1 - 0.87 9.5 4.2 79 3.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat CDC27 PF09507.5 ETS75843.1 - 1.3e-88 298.0 26.2 2e-88 297.4 18.2 1.3 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fe_dep_repress PF01325.14 ETS75843.1 - 0.0022 17.9 0.1 3.3 7.7 0.0 2.5 2 0 0 2 2 2 2 Iron dependent repressor, N-terminal DNA binding domain DUF3653 PF12375.3 ETS75843.1 - 0.55 10.4 4.6 1.6 9.0 0.1 3.6 2 2 1 3 3 3 0 Phage protein zf-C3HC4 PF00097.20 ETS75844.1 - 3.8e-08 32.8 18.2 8.2e-08 31.7 8.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS75844.1 - 2.5e-07 30.2 10.2 2.5e-07 30.2 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS75844.1 - 2.7e-07 30.4 19.1 5.5e-07 29.5 9.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS75844.1 - 4.8e-07 29.5 17.9 1e-06 28.4 8.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETS75844.1 - 8e-07 28.6 12.5 8e-07 28.6 8.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 ETS75844.1 - 1.2e-06 27.9 0.2 2.5e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 ETS75844.1 - 2.6e-06 27.1 7.3 9.2e-06 25.3 2.7 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 ETS75844.1 - 1.7e-05 24.5 16.3 3.3e-05 23.6 8.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS75844.1 - 5e-05 22.9 5.3 5e-05 22.9 3.7 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 ETS75844.1 - 0.0043 17.1 7.9 0.017 15.2 3.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 ETS75844.1 - 0.025 14.5 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 U-box domain Prok-RING_4 PF14447.1 ETS75844.1 - 0.17 11.4 8.2 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Mob_synth_C PF06463.8 ETS75844.1 - 0.3 10.7 8.1 0.11 12.1 3.4 2.0 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C DUF3864 PF12980.2 ETS75844.1 - 0.54 10.5 2.9 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) zf-RING_4 PF14570.1 ETS75844.1 - 1.3 8.6 14.6 0.18 11.4 4.5 2.7 2 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Snf7 PF03357.16 ETS75845.1 - 5.1e-21 74.7 18.0 8.5e-21 74.0 12.2 1.6 1 1 0 1 1 1 1 Snf7 Cu-oxidase_4 PF02578.10 ETS75845.1 - 0.068 12.2 1.4 0.67 8.9 0.1 2.2 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase HHH_2 PF12826.2 ETS75845.1 - 0.1 12.4 0.6 0.94 9.4 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Abhydrolase_2 PF02230.11 ETS75846.1 - 0.0064 15.9 0.1 0.036 13.4 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Nitroreductase PF00881.19 ETS75847.1 - 1.2e-25 90.2 0.1 1.7e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Mononeg_mRNAcap PF14318.1 ETS75848.1 - 0.39 9.7 2.1 1.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V MT PF12777.2 ETS75849.1 - 0.0082 14.9 0.8 0.017 13.8 0.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor HHH_6 PF14579.1 ETS75849.1 - 0.32 11.0 3.2 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3573 PF12097.3 ETS75849.1 - 0.48 8.9 2.3 0.93 8.0 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DinB_2 PF12867.2 ETS75849.1 - 0.86 9.9 5.0 35 4.7 0.5 3.9 2 2 0 2 2 2 0 DinB superfamily COG5 PF10392.4 ETS75849.1 - 0.99 9.3 14.4 9.4 6.2 5.1 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF1515 PF07439.6 ETS75849.1 - 1.4 8.7 10.3 0.24 11.2 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DEAD PF00270.24 ETS75850.1 - 7.4e-42 142.7 0.2 1.3e-41 141.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS75850.1 - 3.9e-18 65.0 0.0 8.4e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 ETS75850.1 - 3.7e-14 52.0 0.1 7.7e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 ETS75850.1 - 0.0029 17.4 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pro-kuma_activ PF09286.6 ETS75851.1 - 5.4e-42 143.2 0.0 1.5e-41 141.7 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS75851.1 - 4.9e-11 42.2 0.3 1.3e-10 40.9 0.1 1.7 1 1 0 1 1 1 1 Subtilase family TRAPPC-Trs85 PF12739.2 ETS75852.1 - 5.2e-114 381.1 0.3 8.4e-114 380.4 0.2 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Catalase PF00199.14 ETS75853.1 - 1.1e-60 205.3 0.0 1.4e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Catalase adh_short PF00106.20 ETS75854.1 - 1.6e-16 60.6 0.2 4.7e-16 59.1 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS75854.1 - 3.4e-10 40.1 0.0 5.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS75854.1 - 1.6e-05 24.6 0.1 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS75854.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PEP_mutase PF13714.1 ETS75856.1 - 1.4e-46 158.6 0.1 1.8e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETS75856.1 - 2.5e-19 68.9 0.1 3.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.6 ETS75857.1 - 2.6e-43 147.6 9.6 3.2e-43 147.3 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PLAC8 PF04749.12 ETS75857.1 - 0.018 15.6 1.5 0.086 13.4 0.1 2.5 3 0 0 3 3 3 0 PLAC8 family MFS_1 PF07690.11 ETS75858.1 - 5e-53 180.0 27.7 2.2e-52 177.9 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS75858.1 - 1.3e-14 53.6 12.8 2.6e-14 52.6 2.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 ETS75858.1 - 1.3e-08 33.5 5.2 2.3e-08 32.7 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS75858.1 - 7.8e-06 24.2 5.5 7.8e-06 24.2 3.8 2.0 3 0 0 3 3 3 1 Transmembrane secretion effector DUF791 PF05631.9 ETS75858.1 - 0.00024 19.9 2.3 0.00024 19.9 1.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF791) PgaD PF13994.1 ETS75858.1 - 0.26 10.7 0.0 0.26 10.7 0.0 3.1 3 0 0 3 3 3 0 PgaD-like protein 2TM PF13239.1 ETS75858.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.2 4 0 0 4 4 4 0 2TM domain V-SNARE_C PF12352.3 ETS75859.1 - 6.8e-15 54.8 0.3 1.7e-14 53.5 0.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 ETS75859.1 - 3.5e-05 23.4 0.2 0.00039 20.0 0.0 2.5 2 1 1 3 3 3 1 Sec20 Occludin_ELL PF07303.8 ETS75859.1 - 0.022 15.4 0.3 0.061 14.0 0.2 1.7 1 0 0 1 1 1 0 Occludin homology domain Sigma70_r4 PF04545.11 ETS75859.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 tRNA-synt_2 PF00152.15 ETS75859.1 - 0.064 12.0 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) FbpA PF05833.6 ETS75859.1 - 0.083 11.4 4.0 0.13 10.7 1.0 2.0 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Katanin_con80 PF13925.1 ETS75859.1 - 0.093 12.4 0.4 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 con80 domain of Katanin IncA PF04156.9 ETS75859.1 - 0.28 10.7 3.0 0.19 11.2 0.6 1.7 2 0 0 2 2 2 0 IncA protein DUF2408 PF10303.4 ETS75859.1 - 0.37 10.9 2.2 0.94 9.5 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DivIC PF04977.10 ETS75859.1 - 4.9 6.7 6.7 4.1 6.9 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator TPK_catalytic PF04263.11 ETS75860.1 - 5.4e-21 74.4 0.0 8.1e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 ETS75860.1 - 1.4e-20 72.7 0.0 2.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 ETS75861.1 - 1.8e-06 27.7 5.7 2.9e-06 27.0 3.9 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 ETS75861.1 - 0.2 11.7 1.8 0.43 10.7 1.3 1.5 1 0 0 1 1 1 0 GCK domain Zn_clus PF00172.13 ETS75862.1 - 0.008 16.0 10.4 0.013 15.3 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS75862.1 - 0.035 12.9 0.4 0.095 11.5 0.1 1.8 2 1 0 2 2 2 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS75863.1 - 9.9e-82 274.8 26.8 1.1e-81 274.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75863.1 - 1.9e-16 59.7 34.7 5e-16 58.3 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS75863.1 - 1.5e-07 30.1 25.0 0.00012 20.5 2.2 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 ETS75863.1 - 4.6e-06 25.4 7.3 1e-05 24.2 5.1 1.5 1 1 0 1 1 1 1 Reduced folate carrier Alpha-amylase PF00128.19 ETS75864.1 - 1.1e-94 317.4 0.0 2.8e-94 316.0 0.0 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DNA_pol_viral_N PF00242.12 ETS75865.1 - 7.7 5.4 13.1 0.56 9.1 1.5 2.3 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 ETS75866.1 - 0.79 7.9 13.0 1.2 7.3 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 ETS75866.1 - 3 6.3 8.7 6.5 5.2 6.0 1.6 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DNA_pol_viral_N PF00242.12 ETS75866.1 - 7.3 5.5 8.8 12 4.7 6.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SKG6 PF08693.5 ETS75867.1 - 0.2 11.0 2.2 0.49 9.7 1.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PBP PF01161.15 ETS75868.1 - 9.8e-23 80.6 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_C14 PF00656.17 ETS75870.1 - 1.2e-69 234.8 0.0 1.4e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 ETS75870.1 - 0.012 15.4 0.1 0.14 12.0 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain WW PF00397.21 ETS75871.1 - 1.9e-05 24.3 4.9 4e-05 23.3 3.4 1.6 1 0 0 1 1 1 1 WW domain Med13_N PF11597.3 ETS75872.1 - 0.039 12.6 0.6 0.048 12.3 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF1682 PF07946.9 ETS75872.1 - 0.72 8.6 4.4 0.88 8.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TPR_MLP1_2 PF07926.7 ETS75873.1 - 0.00011 21.9 41.3 0.088 12.5 11.9 3.3 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Flagellin_C PF00700.16 ETS75873.1 - 0.0015 18.6 14.9 0.45 10.7 0.6 4.0 1 1 2 3 3 3 3 Bacterial flagellin C-terminal helical region Reo_sigmaC PF04582.7 ETS75873.1 - 0.058 12.5 26.1 0.81 8.7 10.0 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fez1 PF06818.10 ETS75873.1 - 0.064 13.2 31.5 0.28 11.1 9.5 3.5 1 1 1 3 3 3 0 Fez1 HrpB7 PF09486.5 ETS75873.1 - 0.068 13.1 23.7 0.042 13.7 3.9 3.6 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.1 ETS75873.1 - 0.09 11.9 29.8 0.19 10.9 10.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 ETS75873.1 - 0.095 11.7 38.8 0.29 10.2 20.3 2.6 1 1 1 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 ETS75873.1 - 0.25 9.0 38.9 0.11 10.1 18.0 2.0 1 1 1 2 2 2 0 Myosin tail EzrA PF06160.7 ETS75873.1 - 0.28 9.3 25.5 0.014 13.5 6.4 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA WEMBL PF05701.6 ETS75873.1 - 2.8 6.3 40.1 0.25 9.7 21.0 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light ADIP PF11559.3 ETS75873.1 - 3.2 7.6 38.3 1.6 8.6 5.3 4.2 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 ETS75873.1 - 3.5 7.5 15.9 10 6.0 0.7 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Filament PF00038.16 ETS75873.1 - 6.5 6.1 32.9 14 5.0 15.0 2.8 1 1 2 3 3 3 0 Intermediate filament protein Osmo_CC PF08946.5 ETS75873.1 - 6.8 6.8 11.7 0.57 10.2 0.7 4.0 5 0 0 5 5 5 0 Osmosensory transporter coiled coil Atg14 PF10186.4 ETS75873.1 - 7.1 5.4 29.4 0.82 8.5 8.1 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 ETS75873.1 - 8.3 6.3 29.4 0.45 10.4 7.7 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) Isochorismatase PF00857.15 ETS75874.1 - 5.3e-24 85.0 0.0 7.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Glycos_transf_1 PF00534.15 ETS75875.1 - 2.9e-36 124.4 0.0 4.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS75875.1 - 4.7e-16 59.1 0.0 8.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETS75875.1 - 4.6e-10 39.6 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETS75875.1 - 6.5e-10 39.3 0.0 1.9e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 ETS75875.1 - 1.1e-07 31.7 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 UDPG_MGDP_dh_N PF03721.9 ETS75876.1 - 2.3e-49 167.3 0.1 2.9e-30 105.0 0.0 2.2 1 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETS75876.1 - 1.8e-32 111.4 0.0 4.2e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 ETS75876.1 - 2.1e-22 79.2 0.0 6.5e-17 61.6 0.0 3.5 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 ETS75876.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS75876.1 - 0.0012 18.5 0.1 1.3 8.6 0.1 2.8 1 1 1 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 ETS75876.1 - 0.0056 16.1 0.0 0.021 14.2 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 ETS75876.1 - 0.0091 15.8 0.0 5.4 6.8 0.0 2.7 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ETS75876.1 - 0.018 14.7 0.0 0.051 13.2 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS75876.1 - 0.045 13.7 0.1 0.51 10.3 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain CoA_trans PF01144.18 ETS75877.1 - 1.6e-99 331.5 2.4 3e-62 209.6 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 ETS75877.1 - 0.00074 19.2 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 ETS75879.1 - 1.2e-36 126.2 23.5 1.8e-36 125.5 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS75879.1 - 1.9e-05 24.2 1.6 6.1e-05 22.5 1.1 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 ETS75879.1 - 0.0041 16.8 1.1 0.027 14.2 0.5 2.5 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans PF04082.13 ETS75880.1 - 0.00063 18.7 1.0 0.0016 17.3 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75880.1 - 0.01 15.7 11.2 0.021 14.7 7.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.20 ETS75883.1 - 1.5e-36 126.1 0.3 4e-36 124.7 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Glyco_hydro_61 PF03443.9 ETS75884.1 - 8.3e-44 150.0 0.2 1e-43 149.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glucodextran_B PF09136.5 ETS75884.1 - 0.079 13.1 2.2 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Glucodextranase, domain B Glyco_hydro_cc PF11790.3 ETS75885.1 - 5.1e-69 232.3 2.2 6e-69 232.1 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.8 ETS75885.1 - 0.036 13.3 1.6 0.091 12.0 1.1 1.7 1 0 0 1 1 1 0 Fip1 motif EF1G PF00647.14 ETS75885.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Thiolase_N PF00108.18 ETS75887.1 - 1e-68 231.1 0.8 1.7e-68 230.5 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS75887.1 - 1.9e-39 133.9 0.3 5.6e-39 132.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 ETS75887.1 - 0.02 14.5 0.4 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 ETS75887.1 - 0.035 14.1 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Amidase PF01425.16 ETS75888.1 - 6.8e-39 133.9 0.0 1.8e-38 132.5 0.0 1.6 1 1 0 1 1 1 1 Amidase AhpC-TSA PF00578.16 ETS75889.1 - 2.1e-37 127.5 0.0 2.8e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS75889.1 - 3.1e-13 49.4 0.0 4.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 ETS75889.1 - 1e-11 44.2 0.0 1.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF4139 PF13598.1 ETS75890.1 - 1.8e-24 86.6 2.1 9.7e-15 54.6 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 ETS75890.1 - 2.3e-11 44.0 0.2 2.3e-11 44.0 0.1 3.2 2 2 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Peptidase_S49_N PF08496.5 ETS75890.1 - 2.3 7.9 4.9 6.1 6.6 3.4 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fungal_trans PF04082.13 ETS75891.1 - 1.6e-09 37.0 0.0 2.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS75891.1 - 1.3e-05 24.9 7.9 2.3e-05 24.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 ETS75892.1 - 6.1e-71 239.5 1.9 1.2e-51 175.9 0.0 2.7 2 1 0 2 2 2 2 Amidase Methyltransf_10 PF05971.7 ETS75893.1 - 1.6e-61 208.0 0.0 2.2e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 ETS75893.1 - 4.3e-07 30.5 0.0 1.8e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS75893.1 - 2.9e-06 27.2 0.1 1.9e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETS75893.1 - 3.9e-05 23.1 0.0 9.1e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS75893.1 - 0.00019 21.0 0.0 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75893.1 - 0.0094 16.4 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS75893.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 ETS75893.1 - 0.04 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 p450 PF00067.17 ETS75894.1 - 6.8e-76 255.6 0.4 8.9e-76 255.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 ETS75894.1 - 3.6e-24 85.4 0.0 1.1e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETS75894.1 - 4.4e-19 68.9 0.0 1.2e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 ETS75894.1 - 6.1e-15 55.7 0.0 3e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 ETS75894.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain DUF2236 PF09995.4 ETS75894.1 - 0.062 12.5 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) RRM_1 PF00076.17 ETS75895.1 - 3.5e-09 36.1 0.0 0.0031 17.1 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS75895.1 - 4.2e-09 36.2 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS75895.1 - 7.5e-05 22.5 0.0 0.0012 18.6 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 ETS75895.1 - 0.28 10.0 6.3 0.19 10.6 0.2 2.1 2 0 0 2 2 2 0 AAR2 protein Nop14 PF04147.7 ETS75895.1 - 3.6 5.3 26.9 0.0067 14.4 11.1 1.7 2 0 0 2 2 2 0 Nop14-like family Aldedh PF00171.17 ETS75896.1 - 6.7e-135 449.9 0.2 7.5e-135 449.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS75896.1 - 4.3e-06 25.7 0.0 2.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS75896.1 - 7.5e-05 22.0 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) MFS_1 PF07690.11 ETS75897.1 - 9.1e-28 96.9 29.2 9.1e-28 96.9 20.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PDGLE PF13190.1 ETS75897.1 - 0.013 15.1 0.0 0.052 13.2 0.0 2.1 1 0 0 1 1 1 0 PDGLE domain GHMP_kinases_N PF00288.21 ETS75898.1 - 1.5e-15 56.9 1.7 3.4e-15 55.8 1.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS75898.1 - 1.8e-06 28.0 0.0 4.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal T4_gp9_10 PF07880.6 ETS75898.1 - 0.093 11.7 0.3 0.3 10.0 0.0 1.9 3 0 0 3 3 3 0 Bacteriophage T4 gp9/10-like protein Sugar_tr PF00083.19 ETS75900.1 - 1.3e-73 248.0 23.7 1.5e-73 247.8 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS75900.1 - 2e-21 76.1 30.1 2e-21 76.1 20.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS75900.1 - 2.4e-05 22.9 23.5 0.00017 20.1 1.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Pantoate_ligase PF02569.10 ETS75901.1 - 8.3e-79 264.2 0.0 1.4e-78 263.5 0.0 1.3 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DUF1237 PF06824.6 ETS75902.1 - 1.3e-177 590.7 0.0 1.5e-177 590.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aminotran_1_2 PF00155.16 ETS75903.1 - 1.3e-13 50.6 0.0 4.1e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS75903.1 - 0.05 12.1 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MOZ_SAS PF01853.13 ETS75904.1 - 1.6e-85 285.1 0.6 2.2e-85 284.6 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 ETS75904.1 - 4.3e-18 64.7 0.3 2.4e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RPA_C PF08784.6 ETS75904.1 - 0.11 12.9 1.3 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Replication protein A C terminal Acetyltransf_1 PF00583.19 ETS75904.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_H2_suC PF08615.6 ETS75905.1 - 8.2e-25 87.2 0.0 9.9e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 ETS75906.1 - 4.4e-68 229.3 0.0 7.3e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 ETS75906.1 - 2.4e-11 43.9 0.0 4.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS75906.1 - 1.8e-10 40.7 0.0 3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS75906.1 - 9.4e-09 35.8 0.0 2.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS75906.1 - 1.4e-08 34.4 0.0 3e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS75906.1 - 5.8e-06 26.3 0.0 1.5e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS75906.1 - 7.9e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ETS75906.1 - 3.9e-05 22.7 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 ETS75906.1 - 0.00066 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 ETS75906.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 ETS75906.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 ETS75906.1 - 0.031 13.6 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 ETS75906.1 - 0.035 13.6 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) GLTP PF08718.6 ETS75907.1 - 1.1e-46 158.5 0.0 4e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Cu-oxidase_3 PF07732.10 ETS75908.1 - 1.2e-20 73.3 0.2 3.7e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS75908.1 - 2.2e-20 72.5 7.9 5.9e-19 67.9 1.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS75908.1 - 1.2e-06 28.5 0.1 4.5e-05 23.4 0.1 2.8 2 0 0 2 2 2 1 Multicopper oxidase Tannase PF07519.6 ETS75909.1 - 4.3e-105 352.1 1.8 5.7e-105 351.7 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase NMD3 PF04981.8 ETS75910.1 - 2.1e-74 249.5 1.4 2.9e-74 249.1 1.0 1.2 1 0 0 1 1 1 1 NMD3 family FoP_duplication PF13865.1 ETS75910.1 - 0.24 11.8 2.8 0.41 11.1 2.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DZR PF12773.2 ETS75910.1 - 0.26 11.1 10.0 1.6 8.5 4.9 2.9 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 ETS75910.1 - 1.3 8.9 5.1 5.8 6.8 1.8 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF4412 PF14371.1 ETS75913.1 - 0.11 12.9 0.1 0.52 10.8 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4412) p450 PF00067.17 ETS75914.1 - 2.8e-47 161.2 0.0 4.7e-47 160.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS75915.1 - 9.7e-35 119.9 32.5 9.7e-35 119.9 22.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 ETS75915.1 - 0.0015 16.6 4.6 0.0047 15.0 1.9 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 ETS75915.1 - 0.018 15.0 8.1 1.6 8.7 0.3 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF1228) Amidohydro_1 PF01979.15 ETS75916.1 - 3.8e-42 145.1 0.2 4.7e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS75916.1 - 3.3e-23 83.0 0.4 8.6e-23 81.7 0.3 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS75916.1 - 1.3e-13 50.5 0.0 4.5e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS75916.1 - 1.3e-12 47.7 2.8 1.6e-10 40.8 0.2 2.5 2 1 0 2 2 2 2 Amidohydrolase family Thioredoxin_2 PF13098.1 ETS75916.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3604 PF12228.3 ETS75917.1 - 1.1e-10 40.4 0.1 0.00012 20.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3604) MFS_1 PF07690.11 ETS75918.1 - 6.1e-28 97.5 10.3 2.2e-27 95.7 6.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS75919.1 - 7.3e-20 70.9 0.6 1.2e-19 70.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 ETS75920.1 - 1.7e-50 171.2 19.6 2e-50 170.9 13.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ank_2 PF12796.2 ETS75921.1 - 4.9e-83 273.5 11.7 3.2e-20 72.2 0.0 5.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS75921.1 - 2.3e-54 178.6 23.7 1.1e-06 28.0 0.2 13.4 12 1 1 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 ETS75921.1 - 1.4e-50 168.8 9.4 3.1e-10 40.2 0.1 9.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS75921.1 - 1e-44 146.0 6.6 7.3e-05 22.6 0.0 12.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 ETS75921.1 - 1e-40 136.7 15.5 2.7e-06 27.4 0.1 11.3 2 2 10 12 12 12 11 Ankyrin repeats (many copies) NACHT PF05729.7 ETS75921.1 - 1.4e-05 24.8 0.0 4.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.9 ETS75921.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 ETS75921.1 - 0.0004 20.4 0.0 0.0019 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 ETS75921.1 - 0.00088 18.3 0.0 0.84 8.5 0.0 2.6 1 1 1 2 2 2 2 KAP family P-loop domain AAA_22 PF13401.1 ETS75921.1 - 0.0059 16.7 0.0 0.055 13.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS75921.1 - 0.011 15.2 0.1 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Cutinase PF01083.17 ETS75921.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA PF00004.24 ETS75921.1 - 0.029 14.5 0.0 0.089 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 ETS75921.1 - 0.045 12.6 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 ETS75921.1 - 0.06 12.3 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PGAP1 PF07819.8 ETS75921.1 - 0.073 12.6 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 ETS75921.1 - 0.074 12.6 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 1 0 Lipase (class 3) p450 PF00067.17 ETS75922.1 - 3.7e-48 164.2 0.0 5e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Apt1 PF10351.4 ETS75924.1 - 0.26 10.0 2.0 0.38 9.5 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain p450 PF00067.17 ETS75925.1 - 8e-53 179.5 0.0 1e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ric8 PF10165.4 ETS75925.1 - 0.23 10.2 0.4 0.33 9.7 0.3 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn GST_N_3 PF13417.1 ETS75926.1 - 6.9e-13 48.6 0.0 4e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS75926.1 - 5.7e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS75926.1 - 3e-10 40.1 0.0 5.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS75926.1 - 5.7e-10 39.0 0.0 9.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS75926.1 - 0.00027 21.3 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS75926.1 - 0.0051 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.15 ETS75927.1 - 1e-52 178.7 0.0 6e-52 176.2 0.0 2.1 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 ETS75928.1 - 5.9e-06 25.3 6.3 6.5e-06 25.2 3.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.14 ETS75929.1 - 2e-15 57.0 0.0 2.6e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_A PF00848.14 ETS75930.1 - 1.3e-15 57.6 2.4 2.3e-15 56.7 1.7 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS75930.1 - 1.1e-13 50.4 0.0 1.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.11 ETS75931.1 - 1.9e-18 66.3 34.0 1.9e-18 66.3 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily T_cell_tran_alt PF15128.1 ETS75931.1 - 0.21 11.0 3.5 0.32 10.4 0.0 2.7 3 0 0 3 3 3 0 T-cell leukemia translocation-altered DAO PF01266.19 ETS75932.1 - 4.2e-42 144.3 1.7 5.1e-42 144.0 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS75932.1 - 0.0011 18.8 1.0 0.0068 16.2 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS75932.1 - 0.0068 15.3 0.4 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS75932.1 - 0.023 14.6 0.2 0.26 11.3 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS75932.1 - 0.024 13.7 3.4 0.026 13.6 1.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS75932.1 - 0.066 12.7 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 ETS75932.1 - 0.067 12.8 1.0 0.53 9.9 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 ETS75932.1 - 0.083 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.19 ETS75932.1 - 0.43 9.3 7.0 29 3.3 4.8 2.1 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.19 ETS75933.1 - 1.3e-10 40.7 0.0 1.4e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF3433 PF11915.3 ETS75934.1 - 1.9e-22 79.2 18.1 7.5e-14 51.6 1.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) LysM PF01476.15 ETS75935.1 - 4.9e-10 39.1 0.1 0.017 14.9 0.0 4.0 4 0 0 4 4 4 3 LysM domain DUF1153 PF06627.6 ETS75935.1 - 0.14 11.9 0.6 3.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) APO_RNA-bind PF05634.6 ETS75935.1 - 0.15 11.2 0.2 6.7 5.8 0.0 2.1 2 0 0 2 2 2 0 APO RNA-binding DUF4597 PF15366.1 ETS75935.1 - 8.3 6.0 10.2 1.3 8.6 0.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) SET PF00856.23 ETS75936.1 - 4.2e-08 33.6 0.1 1.8e-07 31.6 0.0 1.9 2 1 0 2 2 2 1 SET domain MFS_1 PF07690.11 ETS75937.1 - 8.9e-12 44.3 38.8 1.5e-11 43.6 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS75937.1 - 0.00013 21.5 7.1 0.00036 20.0 4.9 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Acetyltransf_7 PF13508.1 ETS75938.1 - 3.7e-07 30.1 0.0 7.5e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS75938.1 - 1.5e-05 24.9 0.0 0.00023 21.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS75938.1 - 0.0036 17.1 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS75938.1 - 0.05 13.7 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GSH-S_ATP PF02955.11 ETS75939.1 - 3.8e-05 22.9 0.0 5.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 ETS75939.1 - 0.00057 19.6 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Herpes_UL74 PF07982.7 ETS75939.1 - 0.11 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins DUF3176 PF11374.3 ETS75940.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Aldedh PF00171.17 ETS75942.1 - 4.2e-105 351.7 2.2 1.5e-102 343.3 1.5 2.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Acyl_transf_1 PF00698.16 ETS75944.1 - 2.6e-64 217.5 0.0 4.8e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 ETS75944.1 - 4.7e-59 199.9 0.1 9.5e-59 198.9 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS75944.1 - 8.6e-54 181.9 0.2 2.1e-53 180.6 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS75944.1 - 2.4e-42 145.1 0.2 4.1e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS75944.1 - 3.4e-39 134.4 0.1 9.5e-39 132.9 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS75944.1 - 4.2e-30 104.0 0.2 1.7e-29 102.1 0.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS75944.1 - 6.4e-17 61.8 0.0 2.4e-16 60.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS75944.1 - 2.7e-16 59.3 0.1 9e-16 57.6 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 ETS75944.1 - 2.3e-14 53.4 0.0 7.3e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS75944.1 - 1.5e-10 40.8 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS75944.1 - 3.9e-10 40.2 0.0 2.8e-09 37.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS75944.1 - 3.2e-09 37.1 0.0 1.2e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS75944.1 - 4.7e-09 37.2 0.0 4.3e-08 34.1 0.0 2.7 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS75944.1 - 1.6e-08 34.2 0.4 4.5e-08 32.8 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS75944.1 - 1.1e-07 32.0 0.1 2.6e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DREV PF05219.7 ETS75944.1 - 0.00049 19.0 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_25 PF13649.1 ETS75944.1 - 0.00085 19.6 0.0 0.0032 17.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS75944.1 - 0.0016 18.4 0.0 0.0096 15.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS75944.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ETS75944.1 - 0.2 10.6 0.0 0.45 9.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Thiolase_N PF00108.18 ETS75944.1 - 0.88 8.4 3.8 6 5.7 2.6 2.1 1 1 0 1 1 1 0 Thiolase, N-terminal domain TauD PF02668.11 ETS75945.1 - 6e-56 189.9 0.3 7.6e-56 189.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 ETS75947.1 - 1.1e-48 165.7 20.7 1.6e-48 165.2 13.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Syntaxin-18_N PF10496.4 ETS75948.1 - 1.6e-13 50.2 0.2 8.1e-13 48.0 0.1 2.2 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus AAA_32 PF13654.1 ETS75948.1 - 0.57 8.7 8.6 1.1 7.7 1.3 2.2 2 1 0 2 2 2 0 AAA domain Phage_int_SAM_2 PF12834.2 ETS75948.1 - 1.1 9.6 5.4 0.53 10.7 0.1 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal Aminotran_1_2 PF00155.16 ETS75949.1 - 2.6e-86 289.8 0.0 3e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Macro_2 PF14519.1 ETS75950.1 - 0.0041 16.2 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 ETS75950.1 - 0.089 12.6 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Macro domain F-box PF00646.28 ETS75951.1 - 4.8e-05 22.8 0.7 0.00013 21.4 0.5 1.7 1 0 0 1 1 1 1 F-box domain BSP_II PF05432.6 ETS75951.1 - 2 7.6 26.2 1.5 8.0 15.2 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Lipase_GDSL PF00657.17 ETS75952.1 - 9.3e-17 61.6 0.3 1.2e-16 61.2 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS75952.1 - 1.6e-13 51.1 0.0 2.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 ETS75952.1 - 2.5e-05 24.0 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Asp PF00026.18 ETS75953.1 - 6.2e-67 226.1 8.9 2e-64 217.8 6.2 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS75953.1 - 3.3e-10 40.1 0.3 2.1e-09 37.5 0.2 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS75953.1 - 7.4e-05 23.1 0.8 0.22 12.0 0.1 3.4 2 1 0 2 2 2 2 Aspartyl protease ADH_N PF08240.7 ETS75954.1 - 2.2e-21 75.6 0.7 3.7e-21 74.9 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS75954.1 - 2.4e-21 75.6 0.3 4.2e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 ETS75954.1 - 0.003 16.4 0.2 0.0037 16.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 ETS75954.1 - 0.02 14.4 0.3 0.032 13.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 ETS75954.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 ETS75954.1 - 0.56 10.0 3.0 0.94 9.2 1.6 1.6 1 1 0 1 1 1 0 ThiF family ABC_tran PF00005.22 ETS75955.1 - 3.4e-47 160.1 1.1 1.4e-23 83.6 0.0 3.8 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 ETS75955.1 - 1.2e-17 64.8 0.2 0.00085 19.3 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 ETS75955.1 - 4.7e-17 61.9 0.8 2.2e-05 23.7 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS75955.1 - 4.9e-10 38.8 0.0 0.0014 18.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS75955.1 - 2.9e-08 33.9 0.0 0.0003 20.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 ETS75955.1 - 4.4e-08 33.9 0.0 0.0063 17.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS75955.1 - 1.2e-07 31.1 0.0 0.00086 18.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 ETS75955.1 - 2.5e-07 31.2 0.2 0.00012 22.4 0.0 3.7 4 1 0 4 4 2 2 AAA domain Dynamin_N PF00350.18 ETS75955.1 - 3e-07 30.3 0.0 0.00041 20.2 0.0 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 ETS75955.1 - 5.1e-07 29.6 0.0 0.0052 16.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 ETS75955.1 - 1.2e-06 28.4 0.0 0.066 13.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 ETS75955.1 - 1.5e-06 28.2 0.0 0.027 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 ETS75955.1 - 2e-06 27.4 0.1 0.26 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 ETS75955.1 - 5.2e-06 26.7 0.4 0.21 11.9 0.0 3.6 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 ETS75955.1 - 6.5e-06 26.6 0.1 0.037 14.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 ETS75955.1 - 6.7e-06 25.4 5.3 0.24 10.3 0.0 4.9 3 2 2 5 5 5 2 AAA ATPase domain AAA PF00004.24 ETS75955.1 - 1.4e-05 25.3 0.0 0.21 11.7 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 ETS75955.1 - 1.8e-05 24.5 0.0 0.054 13.4 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 ETS75955.1 - 2.6e-05 23.9 0.0 0.34 10.6 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 ETS75955.1 - 6.3e-05 22.4 0.0 0.094 12.1 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 ETS75955.1 - 6.8e-05 23.0 0.0 0.62 10.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 ETS75955.1 - 8.9e-05 21.3 0.8 0.35 9.5 0.0 2.7 3 0 0 3 3 3 2 ArgK protein AAA_16 PF13191.1 ETS75955.1 - 0.00013 22.0 1.5 0.87 9.5 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS75955.1 - 0.00013 21.7 0.0 0.37 10.4 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 ETS75955.1 - 0.00016 21.3 0.0 0.074 12.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 ETS75955.1 - 0.00018 21.4 0.0 0.98 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain HEAT_2 PF13646.1 ETS75955.1 - 0.00021 21.5 4.2 0.92 9.8 0.0 3.3 1 1 2 3 3 3 1 HEAT repeats ParcG PF10274.4 ETS75955.1 - 0.00067 19.6 1.8 1.2 9.0 0.0 3.1 1 1 2 3 3 3 2 Parkin co-regulated protein DUF87 PF01935.12 ETS75955.1 - 0.00068 19.5 0.3 0.91 9.2 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 cobW PF02492.14 ETS75955.1 - 0.00099 18.5 0.2 2.4 7.5 0.0 3.6 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 ETS75955.1 - 0.0021 16.6 5.6 1.1 7.5 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_30 PF13604.1 ETS75955.1 - 0.0038 16.8 0.1 4.1 6.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain Septin PF00735.13 ETS75955.1 - 0.0044 16.0 1.6 0.94 8.4 0.0 3.2 3 0 0 3 3 3 1 Septin MutS_V PF00488.16 ETS75955.1 - 0.0054 16.1 0.0 0.6 9.4 0.0 2.6 2 0 0 2 2 2 1 MutS domain V HEAT PF02985.17 ETS75955.1 - 0.011 15.7 0.7 84 3.6 0.1 4.5 4 0 0 4 4 3 0 HEAT repeat ATP_bind_1 PF03029.12 ETS75955.1 - 0.011 15.2 0.0 6.9 6.1 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 ETS75955.1 - 0.014 14.8 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 ETS75955.1 - 0.018 14.4 0.0 6.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 ETS75955.1 - 0.019 14.1 0.0 3.1 6.9 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MMS19_N PF14500.1 ETS75955.1 - 0.023 13.9 1.6 0.34 10.1 0.2 2.6 1 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II FtsK_SpoIIIE PF01580.13 ETS75955.1 - 0.027 13.9 0.9 3.9 6.8 0.0 3.3 4 0 0 4 4 2 0 FtsK/SpoIIIE family PRK PF00485.13 ETS75955.1 - 0.029 13.9 0.0 0.94 9.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 ETS75955.1 - 0.051 12.2 0.0 4.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DAP3 PF10236.4 ETS75955.1 - 0.06 12.2 6.2 0.5 9.2 0.6 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 HEAT_EZ PF13513.1 ETS75955.1 - 0.49 10.9 5.6 1.9e+02 2.7 0.0 5.1 5 1 1 6 6 4 0 HEAT-like repeat SIR2 PF02146.12 ETS75957.1 - 7.4e-24 84.4 2.2 3.5e-11 43.1 0.0 3.5 3 0 0 3 3 3 3 Sir2 family CTP_transf_1 PF01148.15 ETS75958.1 - 5.4e-80 268.7 28.7 6.6e-80 268.5 19.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 ETS75959.1 - 1.9e-32 111.9 0.1 3.7e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) TFIIA PF03153.8 ETS75959.1 - 3.3 7.5 24.1 5.5 6.7 16.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETS75959.1 - 4.3 5.4 35.5 7.3 4.6 24.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_gE PF02480.11 ETS75960.1 - 0.0047 15.2 0.0 0.0056 15.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 ETS75960.1 - 0.096 12.3 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family Glyco_hydro_16 PF00722.16 ETS75961.1 - 1.9e-39 134.9 7.8 1.9e-39 134.9 5.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.6 ETS75961.1 - 0.066 11.0 7.6 0.075 10.8 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 ETS75961.1 - 6.5 4.9 9.0 8.5 4.5 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein TPR_12 PF13424.1 ETS75962.1 - 6.6e-05 22.7 0.3 0.7 9.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat LSM PF01423.17 ETS75962.1 - 0.085 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 LSM domain Clr5 PF14420.1 ETS75963.1 - 2.1e-11 43.5 1.1 2.7e-11 43.1 0.7 1.2 1 0 0 1 1 1 1 Clr5 domain DUF4314 PF14192.1 ETS75963.1 - 0.065 13.5 0.1 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) PD40 PF07676.7 ETS75964.1 - 3e-35 119.3 21.6 2e-06 27.3 1.8 10.0 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETS75964.1 - 3.3e-09 35.8 5.7 0.069 11.7 0.2 6.6 5 1 1 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 ETS75964.1 - 0.04 12.8 0.1 21 3.8 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) FAD_binding_4 PF01565.18 ETS75965.1 - 1.7e-22 79.3 0.6 5.2e-22 77.8 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS75965.1 - 0.031 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF3353 PF11833.3 ETS75966.1 - 0.4 10.1 4.9 1.5 8.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) Abhydrolase_5 PF12695.2 ETS75967.1 - 8.8e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETS75967.1 - 4.2e-06 26.1 0.1 1.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS75967.1 - 0.00011 21.4 0.0 0.00037 19.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 ETS75967.1 - 0.00094 18.6 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 ETS75967.1 - 0.0032 16.0 0.1 0.011 14.2 0.1 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 ETS75967.1 - 0.0059 16.5 0.1 2.5 7.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS75967.1 - 0.069 12.5 0.1 0.36 10.2 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase tRNA-synt_1c PF00749.16 ETS75968.1 - 3.6e-96 321.5 0.0 5e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETS75968.1 - 4.1e-32 111.2 0.0 1.4e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fructosamin_kin PF03881.9 ETS75969.1 - 8.3e-32 110.3 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS75969.1 - 1.5e-08 34.7 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS75969.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase BNR_2 PF13088.1 ETS75970.1 - 3e-10 39.8 2.8 0.0032 16.7 0.0 3.9 1 1 2 4 4 4 4 BNR repeat-like domain BNR PF02012.15 ETS75970.1 - 0.02 14.6 19.7 0.088 12.6 0.4 5.6 5 0 0 5 5 5 0 BNR/Asp-box repeat Pro-kuma_activ PF09286.6 ETS75971.1 - 1.6e-35 122.2 0.2 8.5e-34 116.6 0.0 2.2 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS75971.1 - 1e-07 31.3 5.3 1.9e-07 30.5 3.7 1.4 1 0 0 1 1 1 1 Subtilase family GMC_oxred_N PF00732.14 ETS75972.1 - 7.2e-60 202.6 0.0 9.7e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS75972.1 - 9.9e-35 119.9 0.0 1.7e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS75972.1 - 2.5e-05 23.3 0.0 0.0049 15.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS75972.1 - 0.00081 18.4 0.0 0.003 16.5 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS75972.1 - 0.0098 15.8 1.8 0.014 15.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS75972.1 - 0.016 15.1 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATG16 PF08614.6 ETS75973.1 - 0.0035 17.1 0.2 0.0057 16.4 0.2 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Sigma70_ner PF04546.8 ETS75973.1 - 0.0056 16.3 0.2 0.0056 16.3 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, non-essential region TPR_MLP1_2 PF07926.7 ETS75973.1 - 0.01 15.5 1.2 0.018 14.8 0.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 ETS75973.1 - 0.018 14.3 1.5 0.025 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 ETS75973.1 - 0.023 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 ETS75973.1 - 0.028 14.1 0.2 0.043 13.5 0.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Nsp1_C PF05064.8 ETS75973.1 - 0.051 13.2 0.6 0.088 12.4 0.4 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region APG6 PF04111.7 ETS75973.1 - 0.07 12.1 1.0 0.093 11.7 0.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 ETS75973.1 - 1.1 7.5 5.0 1.6 7.0 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.11 ETS75975.1 - 1.4e-37 129.2 43.9 5.1e-37 127.4 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS75975.1 - 3.9e-09 35.6 11.8 3.9e-09 35.6 8.1 3.9 1 1 3 5 5 5 1 Sugar (and other) transporter Tub_2 PF04525.7 ETS75976.1 - 4.6e-07 29.4 0.3 5.3e-06 25.9 0.2 2.0 1 1 0 1 1 1 1 Tubby C 2 NYAP_C PF15452.1 ETS75976.1 - 0.00025 20.1 0.0 0.0003 19.8 0.0 1.0 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF826 PF05696.6 ETS75977.1 - 0.0077 16.3 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF826) DUF399 PF04187.8 ETS75977.1 - 0.02 14.4 0.1 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF399 UPF0542 PF15086.1 ETS75978.1 - 0.0021 17.7 1.4 0.0021 17.7 1.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0542 SpoVR PF04293.8 ETS75978.1 - 0.0078 14.6 1.3 0.01 14.2 0.9 1.1 1 0 0 1 1 1 1 SpoVR like protein UPF0233 PF06781.7 ETS75978.1 - 1.1 8.9 3.4 1.9 8.1 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) U79_P34 PF03064.11 ETS75978.1 - 1.7 8.1 18.1 2.5 7.5 12.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pyridoxal_deC PF00282.14 ETS75979.1 - 2.1e-119 398.2 0.0 2.5e-119 398.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain LysM PF01476.15 ETS75980.1 - 1.6e-19 69.5 7.0 1.4e-07 31.3 0.1 6.4 6 0 0 6 6 6 4 LysM domain DUF1153 PF06627.6 ETS75980.1 - 0.098 12.5 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Glyco_hydro_18 PF00704.23 ETS75981.1 - 6.8e-80 269.0 2.9 1.2e-79 268.2 2.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS75981.1 - 7e-08 32.3 14.3 7e-08 32.3 9.9 4.7 4 0 0 4 4 4 2 Chitin recognition protein EthD PF07110.6 ETS75983.1 - 3.6e-12 47.0 0.1 4.6e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 EthD domain Acyl_transf_1 PF00698.16 ETS75984.1 - 1.1e-86 291.0 0.2 1.1e-86 291.0 0.1 1.6 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.21 ETS75984.1 - 1.3e-80 270.6 0.0 3.4e-80 269.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS75984.1 - 1.8e-57 193.9 0.1 4.3e-57 192.6 0.1 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS75984.1 - 5.5e-49 166.2 0.1 1.4e-48 164.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS75984.1 - 2e-39 134.1 1.6 1.4e-38 131.3 1.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 ETS75984.1 - 7.6e-17 61.3 0.1 1.9e-16 60.0 0.1 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 ETS75984.1 - 7e-10 39.0 0.0 2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS75984.1 - 0.00037 19.5 0.3 0.001 18.0 0.2 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain HLH PF00010.21 ETS75985.1 - 4.1e-13 48.7 0.1 8e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 ETS75985.1 - 0.097 12.1 0.3 0.097 12.1 0.2 1.9 2 0 0 2 2 2 0 Septum formation initiator Herpes_DNAp_acc PF04929.7 ETS75985.1 - 1.1 8.1 4.3 1.6 7.5 3.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mg_trans_NIPA PF05653.9 ETS75986.1 - 3.5e-64 216.6 4.7 2.9e-61 207.0 1.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 ETS75986.1 - 0.00041 20.3 27.9 0.00078 19.4 2.4 4.0 3 1 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 ETS75986.1 - 0.00048 20.3 0.1 0.00048 20.3 0.1 3.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Iron_permease PF04120.7 ETS75986.1 - 0.012 15.1 1.0 0.14 11.7 0.0 2.8 3 0 0 3 3 3 0 Low affinity iron permease DUF1183 PF06682.7 ETS75986.1 - 0.042 13.4 1.1 0.093 12.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Trp_oprn_chp PF09534.5 ETS75986.1 - 0.062 12.9 0.2 49 3.4 0.0 3.5 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LRR19-TM PF15176.1 ETS75986.1 - 0.1 12.3 0.9 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Ctr PF04145.10 ETS75986.1 - 0.11 12.5 1.8 1.9 8.5 0.1 3.0 3 1 0 3 3 3 0 Ctr copper transporter family WD40 PF00400.27 ETS75987.1 - 2e-22 78.1 19.1 2.7e-06 27.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_N PF14781.1 ETS75987.1 - 0.044 13.4 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal MraZ PF02381.13 ETS75987.1 - 0.087 12.5 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 MraZ protein Cwf_Cwc_15 PF04889.7 ETS75987.1 - 0.51 9.9 8.3 0.99 9.0 5.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SNF2_N PF00176.18 ETS75988.1 - 4e-83 278.6 1.1 4e-83 278.6 0.7 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 ETS75988.1 - 3.7e-22 78.0 0.3 1.2e-21 76.4 0.2 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 ETS75988.1 - 1.5e-19 69.6 0.3 5.7e-17 61.3 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 ETS75988.1 - 2.3e-17 62.8 0.9 2.3e-17 62.8 0.7 3.9 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 ETS75988.1 - 4.6e-13 48.7 14.3 4.6e-13 48.7 9.9 3.5 4 0 0 4 4 4 1 HSA QLQ PF08880.6 ETS75988.1 - 2.2e-07 30.1 9.5 5.8e-07 28.8 6.6 1.8 1 0 0 1 1 1 1 QLQ ANTAR PF03861.9 ETS75989.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 ANTAR domain MFS_1 PF07690.11 ETS75990.1 - 3.9e-24 85.0 37.1 5.2e-24 84.6 25.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_transf_3 PF02515.12 ETS75991.1 - 2e-60 203.3 0.0 2.7e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 ETS75992.1 - 2.9e-31 108.6 4.9 5.4e-31 107.7 3.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS75992.1 - 1e-17 64.7 0.1 2.8e-17 63.3 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS75992.1 - 1.5e-14 54.4 4.5 1.5e-14 54.4 3.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS75992.1 - 2.8e-14 52.3 0.4 2.8e-14 52.3 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Carboxyl_trans PF01039.17 ETS75993.1 - 1.7e-77 260.8 0.1 3.3e-76 256.6 0.0 2.4 2 1 0 2 2 2 2 Carboxyl transferase domain CPSase_L_D2 PF02786.12 ETS75994.1 - 7.8e-54 182.1 0.0 1.1e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 ETS75994.1 - 3.7e-29 100.8 0.0 4.3e-28 97.4 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 ETS75994.1 - 2e-28 98.6 0.0 4.6e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 ETS75994.1 - 8.4e-16 58.2 0.1 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 ETS75994.1 - 6.7e-13 48.0 0.1 2e-12 46.5 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 ETS75994.1 - 4.8e-12 45.2 0.0 6.7e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 ETS75994.1 - 8.3e-08 31.7 2.2 3.3e-07 29.8 0.4 2.6 2 1 1 3 3 3 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 ETS75994.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF2118 PF09891.4 ETS75994.1 - 0.00079 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 ETS75994.1 - 0.001 18.2 0.0 0.017 14.2 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 ETS75994.1 - 0.0015 18.2 0.0 0.0042 16.7 0.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 ETS75994.1 - 0.0068 15.7 1.1 0.015 14.6 0.6 1.6 1 1 0 1 1 1 1 HlyD family secretion protein DUF3182 PF11379.3 ETS75994.1 - 0.015 14.0 0.1 0.54 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) ATP-grasp_3 PF02655.9 ETS75994.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.1 ETS75994.1 - 0.024 14.9 0.2 5.5 7.3 0.1 2.7 1 1 1 2 2 2 0 HlyD family secretion protein RimK PF08443.6 ETS75994.1 - 0.081 12.3 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Sad1_UNC PF07738.8 ETS75995.1 - 2.1e-36 124.6 0.0 4.6e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Kinesin-relat_1 PF12711.2 ETS75995.1 - 2.8 8.3 7.1 0.21 11.9 1.2 2.0 2 0 0 2 2 2 0 Kinesin motor RRM_2 PF04059.7 ETS75996.1 - 3.1e-38 129.6 1.0 5.4e-38 128.8 0.7 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 ETS75996.1 - 0.00019 21.0 0.0 0.12 12.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS75996.1 - 0.0004 20.3 0.0 0.081 12.9 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 ETS75997.1 - 8.2e-118 393.2 1.9 8.2e-118 393.2 1.3 2.4 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 ETS75997.1 - 0.0014 18.1 4.2 0.0034 16.8 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3510 PF12022.3 ETS75997.1 - 0.11 12.6 3.0 5.7 7.0 0.0 3.4 3 1 0 4 4 4 0 Domain of unknown function (DUF3510) CBFD_NFYB_HMF PF00808.18 ETS75998.1 - 1.3e-19 69.9 0.6 1.9e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS75998.1 - 2.7e-11 43.4 0.1 4.1e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 ETS75998.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 ETS75999.1 - 6.1e-31 106.3 0.5 1.3e-30 105.2 0.3 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing RRM_6 PF14259.1 ETS76001.1 - 2e-12 46.8 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS76001.1 - 1e-10 41.0 0.0 1.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS76001.1 - 4.7e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_N PF03234.9 ETS76001.1 - 7.8 6.7 10.0 12 6.1 6.9 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding MLANA PF14991.1 ETS76002.1 - 0.05 13.6 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A RseC_MucC PF04246.7 ETS76002.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC B3_4 PF03483.12 ETS76003.1 - 2.4e-27 95.4 0.0 4.5e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 ETS76003.1 - 2.4e-15 56.0 0.0 2.4e-13 49.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 ETS76003.1 - 0.0021 17.3 0.0 0.0044 16.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FliW PF02623.10 ETS76003.1 - 0.008 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 FliW protein Herpes_V23 PF01802.12 ETS76003.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein HEAT PF02985.17 ETS76004.1 - 8.2e-44 143.7 14.1 0.0027 17.6 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 ETS76004.1 - 3.1e-31 107.5 3.5 1.3e-07 31.7 0.0 7.6 3 3 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 ETS76004.1 - 4.9e-10 39.6 5.8 0.02 15.2 0.1 7.4 6 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETS76004.1 - 5.1e-09 36.3 13.8 0.29 11.6 0.0 9.1 8 1 2 10 10 10 2 HEAT-like repeat CLASP_N PF12348.3 ETS76004.1 - 7e-06 25.5 1.0 0.26 10.6 0.0 4.4 3 2 2 5 5 5 2 CLASP N terminal Adaptin_N PF01602.15 ETS76004.1 - 1.7e-05 23.3 9.7 0.18 10.0 0.2 4.7 2 1 1 4 4 4 3 Adaptin N terminal region DUF2435 PF10363.4 ETS76004.1 - 0.0025 17.6 7.1 0.29 11.0 0.2 4.7 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Arm PF00514.18 ETS76004.1 - 0.0075 16.0 1.8 24 4.9 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 ETS76004.1 - 0.031 13.2 1.1 0.2 10.6 0.1 2.6 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain RIX1 PF08167.7 ETS76004.1 - 0.06 13.0 0.2 2.1 8.0 0.0 3.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 ETS76004.1 - 0.065 13.0 6.3 8.4 6.1 0.1 5.4 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Imm25 PF15571.1 ETS76004.1 - 0.16 12.0 1.7 11 6.1 0.0 3.8 3 1 1 4 4 4 0 Immunity protein 25 Proteasom_PSMB PF10508.4 ETS76004.1 - 0.17 10.1 4.3 0.52 8.5 0.1 2.9 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Methyltransf_18 PF12847.2 ETS76005.1 - 6.3e-14 52.5 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76005.1 - 3.9e-11 42.7 0.0 8e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76005.1 - 1e-06 28.5 0.3 1.8e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76005.1 - 4.5e-06 27.0 0.0 1.8e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS76005.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS76005.1 - 0.00024 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76005.1 - 0.00032 20.9 0.0 0.00061 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76005.1 - 0.00042 20.7 0.0 0.0059 17.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 ETS76005.1 - 0.0029 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 ETS76005.1 - 0.037 13.4 0.0 0.086 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain RXT2_N PF08595.6 ETS76005.1 - 0.11 12.2 3.6 0.22 11.3 2.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1676 PF07898.8 ETS76005.1 - 0.33 11.2 1.9 25 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Nucleoplasmin PF03066.10 ETS76005.1 - 1.7 8.1 12.2 0.024 14.1 3.7 1.5 2 0 0 2 2 2 0 Nucleoplasmin DNA_pol_phi PF04931.8 ETS76005.1 - 3.3 5.3 7.9 4.4 4.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pro-kuma_activ PF09286.6 ETS76009.1 - 2.3e-35 121.7 0.1 5.1e-35 120.6 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS76009.1 - 7e-08 31.9 0.1 7e-08 31.9 0.1 1.9 3 0 0 3 3 3 1 Subtilase family DUF4137 PF13593.1 ETS76010.1 - 5.1e-89 298.4 13.9 5.9e-89 298.2 9.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 ETS76010.1 - 1.2e-10 41.1 9.1 1.2e-10 41.1 6.3 2.4 4 0 0 4 4 4 1 Sodium Bile acid symporter family DUF417 PF04224.7 ETS76010.1 - 0.32 10.3 4.9 0.1 11.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF417 Phtf-FEM1B_bdg PF12129.3 ETS76010.1 - 0.83 8.9 4.9 6.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Male germ-cell putative homeodomain transcription factor GFA PF04828.9 ETS76011.1 - 0.00069 19.5 0.7 0.001 18.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 ETS76011.1 - 0.49 9.6 2.5 0.29 10.3 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_1 PF00232.13 ETS76012.1 - 3.8e-154 513.2 0.0 4.4e-154 513.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.6 ETS76013.1 - 3.8e-26 91.9 0.7 6.8e-26 91.0 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Vps16_N PF04841.8 ETS76015.1 - 2.2e-96 322.9 0.0 4.2e-96 321.9 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 ETS76015.1 - 3.1e-77 259.6 0.0 4.6e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Myotub-related PF06602.9 ETS76016.1 - 3.9e-125 417.3 0.0 5.5e-125 416.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 ETS76016.1 - 0.055 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETS76016.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 ETS76017.1 - 1.1e-16 60.7 0.0 2.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 ETS76017.1 - 2.5e-12 46.1 0.1 4.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 ETS76017.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 ETS76018.1 - 2.5e-101 338.6 14.9 3.2e-101 338.2 10.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 ETS76018.1 - 2.3e-08 34.2 22.7 4.9e-08 33.1 2.5 3.6 2 1 1 3 3 3 3 Multidrug resistance efflux transporter EamA PF00892.15 ETS76018.1 - 1.3e-05 25.2 8.4 1.3e-05 25.2 5.8 2.9 2 1 0 2 2 2 2 EamA-like transporter family DUF2420 PF10336.4 ETS76019.1 - 9.7e-05 21.9 0.4 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 ETS76020.1 - 5e-17 61.8 0.0 7.2e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS76020.1 - 1.5e-08 34.4 0.1 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3484 PF11983.3 ETS76020.1 - 0.06 14.1 0.3 0.23 12.3 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Apc4 PF12896.2 ETS76021.1 - 4.3e-58 196.0 0.8 6.9e-58 195.3 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 ETS76021.1 - 0.0056 16.5 0.0 0.074 12.9 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat AMP-binding PF00501.23 ETS76023.1 - 4.1e-73 246.1 0.0 5.3e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS76023.1 - 5.6e-17 62.4 0.0 1.3e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DCP2 PF05026.8 ETS76024.1 - 6.6e-34 115.6 1.3 1.3e-33 114.6 0.9 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 ETS76024.1 - 3.1e-17 62.4 0.0 6.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GET2 PF08690.5 ETS76024.1 - 0.0027 17.0 1.5 0.0027 17.0 1.0 3.1 2 1 1 3 3 3 1 GET complex subunit GET2 BAF1_ABF1 PF04684.8 ETS76024.1 - 10 4.8 15.9 22 3.7 11.0 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Proho_convert PF12177.3 ETS76026.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Prohormone convertase enzyme Pkinase PF00069.20 ETS76027.1 - 3.6e-60 203.3 0.0 6.1e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76027.1 - 1.2e-29 103.1 0.1 3.5e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS76027.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FDF PF09532.5 ETS76027.1 - 0.67 10.5 11.8 1.7 9.2 8.2 1.6 1 0 0 1 1 1 0 FDF domain APH PF01636.18 ETS76027.1 - 0.75 9.4 6.4 4.8 6.8 4.2 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Red1 PF07964.6 ETS76027.1 - 0.97 7.5 7.3 1.5 6.8 5.0 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Macoilin PF09726.4 ETS76027.1 - 1.9 6.7 13.9 2.6 6.2 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein TEX19 PF15553.1 ETS76027.1 - 4.1 7.2 5.7 49 3.7 0.0 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 Methyltransf_28 PF02636.12 ETS76028.1 - 3.1e-78 262.6 0.0 4.1e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HET PF06985.6 ETS76029.1 - 1.7e-28 99.4 0.8 3.8e-28 98.4 0.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 ETS76031.1 - 4.7e-29 101.3 0.0 8.4e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76031.1 - 1.3e-22 80.1 0.0 2.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 ETS76031.1 - 6.6e-19 68.4 0.0 1.5e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 ETS76031.1 - 1.6 9.2 4.6 34 5.0 0.1 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type MFS_1 PF07690.11 ETS76033.1 - 1.6e-53 181.6 30.8 1.6e-53 181.6 21.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76033.1 - 7e-14 51.2 20.2 1.1e-13 50.5 14.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS76033.1 - 2.4e-07 29.3 0.9 4.1e-07 28.5 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 ETS76033.1 - 0.032 12.2 14.6 0.025 12.6 1.6 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TMPIT PF07851.8 ETS76033.1 - 0.23 10.5 2.6 0.42 9.6 1.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein Abhydrolase_5 PF12695.2 ETS76034.1 - 5.6e-10 39.1 0.0 1.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS76034.1 - 2.7e-07 30.0 0.0 4.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.6 ETS76034.1 - 9.9e-07 27.6 0.0 1.9e-06 26.6 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 ETS76034.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 ETS76034.1 - 1.8e-06 28.0 0.4 3.7e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS76034.1 - 0.0047 16.2 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2974 PF11187.3 ETS76034.1 - 0.0085 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Peptidase_S15 PF02129.13 ETS76034.1 - 0.033 13.6 0.0 0.057 12.8 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 ETS76034.1 - 0.057 11.9 0.0 0.1 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 ETS76034.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 ETS76035.1 - 1.8e-29 102.6 28.0 6.7e-16 57.9 4.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS76035.1 - 5.4e-14 51.6 41.4 1.1e-08 34.1 11.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily KRTAP PF11759.3 ETS76035.1 - 0.49 10.6 4.3 0.21 11.8 0.7 2.1 2 0 0 2 2 2 0 Keratin-associated matrix 4HBT_3 PF13622.1 ETS76036.1 - 5.8e-49 167.1 0.3 6.6e-49 166.9 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Sugar_tr PF00083.19 ETS76037.1 - 1.3e-85 287.7 19.2 1.5e-85 287.5 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76037.1 - 3.8e-23 81.7 37.5 5.7e-18 64.7 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS76037.1 - 0.43 10.6 9.0 2.5 8.1 0.1 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF1228) Chitin_synth_2 PF03142.10 ETS76038.1 - 2.5e-41 141.6 2.0 3e-31 108.4 0.4 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS76038.1 - 3e-09 36.8 5.7 3e-09 36.8 4.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS76038.1 - 2.2e-05 24.4 0.3 0.00067 19.5 0.1 2.7 2 1 1 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS76038.1 - 9e-05 22.2 0.0 0.076 12.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF4131 PF13567.1 ETS76038.1 - 0.085 12.2 1.8 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UDPG_MGDP_dh_N PF03721.9 ETS76039.1 - 2.3e-23 82.5 0.0 1.5e-21 76.6 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 ETS76039.1 - 5.4e-18 64.9 0.0 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 ETS76039.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 ETS76039.1 - 0.00047 20.2 0.0 0.00097 19.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 ETS76039.1 - 0.00064 20.2 0.0 0.0087 16.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76039.1 - 0.0013 19.0 0.0 0.005 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain F420_oxidored PF03807.12 ETS76039.1 - 0.0018 18.6 0.0 0.061 13.7 0.0 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 ETS76039.1 - 0.0033 17.4 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 ETS76039.1 - 0.012 15.0 0.0 4 6.8 0.0 3.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Methyltransf_11 PF08241.7 ETS76039.1 - 0.078 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 ETS76039.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.23 ETS76040.1 - 7.9e-70 235.9 0.0 8.9e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3115 PF11312.3 ETS76040.1 - 0.17 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) DUF3716 PF12511.3 ETS76041.1 - 4.5e-17 61.3 8.2 7.6e-17 60.6 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) CDK2AP PF09806.4 ETS76041.1 - 0.079 13.1 3.6 0.16 12.1 2.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NicO PF03824.11 ETS76041.1 - 1.8 7.8 9.7 3.1 7.0 6.7 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF1771 PF08590.5 ETS76042.1 - 3.7e-24 84.4 9.2 3.7e-24 84.4 6.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 ETS76042.1 - 2.7e-16 59.5 0.5 2.7e-16 59.5 0.3 2.2 2 0 0 2 2 2 1 Smr domain DUF2201_N PF13203.1 ETS76042.1 - 0.39 9.8 15.3 0.62 9.1 1.5 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain PAT1 PF09770.4 ETS76042.1 - 1.4 7.0 15.1 1.7 6.7 10.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G-alpha PF00503.15 ETS76043.1 - 7.6e-135 449.5 2.6 9.2e-135 449.2 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS76043.1 - 3.1e-15 55.8 2.0 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 ETS76043.1 - 8.2e-05 22.0 0.0 0.00036 20.0 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 ETS76043.1 - 0.0015 18.9 0.6 2.7 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 ETS76043.1 - 0.0097 15.0 3.8 0.22 10.6 0.1 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 ETS76043.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 ETS76043.1 - 0.027 13.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 ETS76043.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_23 PF13476.1 ETS76043.1 - 0.091 13.0 0.4 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 ETS76043.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 ETS76043.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GST_N PF02798.15 ETS76044.1 - 1.2e-09 38.2 0.1 2.7e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS76044.1 - 2e-07 30.9 0.1 7.2e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS76044.1 - 5.2e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS76044.1 - 1.2e-06 28.9 0.0 2.1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS76044.1 - 1.8e-06 27.8 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS76044.1 - 3.8e-06 26.7 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Prp18 PF02840.10 ETS76045.1 - 1.6e-52 177.2 0.0 1.6e-52 177.2 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 ETS76045.1 - 3.7e-11 42.0 0.5 3.7e-11 42.0 0.4 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 ETS76045.1 - 0.21 10.7 19.6 0.36 9.9 13.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 ETS76045.1 - 0.66 9.4 14.8 1.6 8.2 10.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3340 PF11818.3 ETS76045.1 - 5 7.0 20.3 0.62 10.0 10.6 1.9 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) CDC45 PF02724.9 ETS76045.1 - 9.9 4.0 13.1 14 3.5 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SAP18 PF06487.7 ETS76046.1 - 8.3e-29 99.8 0.0 1.1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) RPN7 PF10602.4 ETS76047.1 - 5.7e-38 130.0 0.0 1.1e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 ETS76047.1 - 3.8e-15 56.0 0.5 1.4e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 ETS76047.1 - 0.28 11.9 7.4 0.25 12.0 0.4 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 ETS76048.1 - 7.1e-30 103.7 0.0 1.1e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76048.1 - 3.7e-11 42.7 13.8 6.2e-11 42.0 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 ETS76048.1 - 0.098 12.6 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain TEBP_beta PF07404.6 ETS76048.1 - 1.6 7.7 3.6 2.8 7.0 2.5 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Peptidase_M24 PF00557.19 ETS76049.1 - 2.9e-55 187.0 0.0 4.1e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETS76049.1 - 8.3e-22 77.0 0.0 1.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Abhydrolase_6 PF12697.2 ETS76050.1 - 5.8e-06 26.3 1.3 5.3e-05 23.1 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76050.1 - 0.0049 16.4 0.0 0.016 14.7 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 ETS76050.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 ETS76050.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) WAC_Acf1_DNA_bd PF10537.4 ETS76051.1 - 5.7e-39 132.3 1.2 1.4e-38 131.1 0.0 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 ETS76051.1 - 6.6e-17 61.0 0.3 1.2e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 ETS76051.1 - 1.7e-14 53.0 0.3 4.1e-14 51.8 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Alg6_Alg8 PF03155.10 ETS76052.1 - 8.9e-142 473.2 29.6 1.2e-141 472.8 20.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MerC PF03203.9 ETS76052.1 - 2 8.8 11.3 0.036 14.4 1.6 2.8 3 1 0 3 3 3 0 MerC mercury resistance protein Lectin_leg-like PF03388.8 ETS76053.1 - 2.9e-23 82.2 0.0 4.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family CENP-F_leu_zip PF10473.4 ETS76053.1 - 0.013 15.3 3.6 0.037 13.8 2.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATP-synt_D PF01813.12 ETS76053.1 - 0.017 14.6 0.4 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 ATP synthase subunit D DUF4391 PF14335.1 ETS76053.1 - 0.02 14.2 2.8 0.032 13.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Laminin_II PF06009.7 ETS76053.1 - 0.038 13.7 4.3 0.067 12.9 3.0 1.3 1 0 0 1 1 1 0 Laminin Domain II Baculo_PEP_C PF04513.7 ETS76053.1 - 0.093 12.5 2.0 0.17 11.7 1.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4011 PF13195.1 ETS76053.1 - 2.1 8.3 5.3 4.1 7.3 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Fib_alpha PF08702.5 ETS76053.1 - 7.8 6.6 10.0 0.53 10.3 3.3 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tetraspannin PF00335.15 ETS76054.1 - 0.0008 18.7 3.7 0.00088 18.6 1.6 1.6 1 1 1 2 2 2 1 Tetraspanin family MIF PF01187.13 ETS76055.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.7 ETS76056.1 - 2.3e-69 233.0 0.2 2.8e-69 232.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 ETS76056.1 - 0.00065 18.9 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETS76056.1 - 0.0022 18.4 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Pkinase PF00069.20 ETS76057.1 - 1.3e-76 257.1 0.0 1.6e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76057.1 - 3.7e-38 131.0 0.0 5.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS76057.1 - 0.021 13.7 0.0 0.076 11.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETS76057.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS76057.1 - 0.11 12.1 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Septin PF00735.13 ETS76058.1 - 5.3e-18 65.0 0.0 5.7e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETS76058.1 - 0.0036 17.2 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Lysis_S PF04971.7 ETS76058.1 - 0.037 13.7 0.2 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 Lysis protein S FtsK_SpoIIIE PF01580.13 ETS76058.1 - 0.09 12.2 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PAP_central PF04928.12 ETS76059.1 - 7.1e-99 329.7 0.0 9.2e-99 329.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 ETS76059.1 - 1.3e-44 151.4 0.1 4.7e-44 149.6 0.0 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 ETS76059.1 - 2.1e-06 27.9 0.0 5.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain UxuA PF03786.8 ETS76060.1 - 0.078 11.5 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) SCA7 PF08313.7 ETS76061.1 - 1.5e-35 120.6 0.2 5.5e-35 118.8 0.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.9 ETS76061.1 - 0.35 8.8 9.2 0.5 8.3 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.22 ETS76062.1 - 5.7e-38 128.5 2.4 4.4e-12 45.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_2 PF13923.1 ETS76063.1 - 1.6e-08 34.4 13.1 6.5e-05 22.8 2.5 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS76063.1 - 2.4e-06 27.1 16.2 0.00022 20.7 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS76063.1 - 2.2e-05 24.0 17.3 0.00011 21.8 4.9 2.8 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS76063.1 - 5.2e-05 22.9 16.3 0.0012 18.6 3.7 2.8 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 ETS76063.1 - 0.0001 21.9 5.2 0.0001 21.9 3.6 3.1 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS76063.1 - 0.00061 19.6 15.8 0.12 12.2 0.9 3.3 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS76063.1 - 0.00063 19.4 1.2 0.00063 19.4 0.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 ETS76063.1 - 0.027 13.9 7.2 1.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif FYVE PF01363.16 ETS76063.1 - 0.086 12.7 16.5 0.17 11.8 4.9 3.3 2 2 1 3 3 3 0 FYVE zinc finger DRP PF06044.7 ETS76063.1 - 0.19 10.6 1.5 0.61 9.0 0.2 2.0 2 0 0 2 2 2 0 Dam-replacing family zf-AD PF07776.10 ETS76063.1 - 3.3 7.7 12.0 1.9 8.5 0.0 3.7 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-4CXXC_R1 PF10497.4 ETS76063.1 - 5.3 7.2 8.5 0.39 10.8 0.5 2.8 2 1 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Acyltransferase PF01553.16 ETS76064.1 - 1.3e-12 47.2 0.0 2.8e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Nnf1 PF03980.9 ETS76065.1 - 1.1e-29 102.6 0.8 1.8e-29 101.9 0.5 1.4 1 0 0 1 1 1 1 Nnf1 ADIP PF11559.3 ETS76065.1 - 0.017 15.0 3.1 0.05 13.5 0.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 ETS76065.1 - 0.031 14.0 2.1 0.046 13.4 0.4 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 ETS76065.1 - 0.087 12.5 3.7 0.067 12.9 0.7 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 ETS76065.1 - 0.21 11.3 3.8 0.097 12.4 0.8 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 ETS76065.1 - 0.35 10.4 6.5 0.13 11.8 2.5 1.6 2 0 0 2 2 2 0 IncA protein CENP-Q PF13094.1 ETS76065.1 - 0.78 9.7 9.6 0.094 12.7 2.6 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FliT PF05400.8 ETS76065.1 - 0.8 10.1 8.8 0.67 10.4 2.6 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Seryl_tRNA_N PF02403.17 ETS76065.1 - 1 9.4 4.4 10 6.1 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PH_9 PF15410.1 ETS76066.1 - 0.00026 21.1 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 ETS76066.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 PH domain NTF2 PF02136.15 ETS76067.1 - 4.5e-22 78.6 0.5 7.3e-22 77.9 0.3 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 ETS76067.1 - 6.8e-10 38.4 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS76067.1 - 9.3e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS76067.1 - 1.1e-07 31.6 0.1 2.8e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS76067.1 - 2.3e-06 27.3 0.0 5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Cytochrom_B561 PF03188.11 ETS76068.1 - 0.0039 17.0 13.7 0.024 14.4 6.6 2.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 AA_permease_C PF13906.1 ETS76068.1 - 0.0081 16.0 1.3 0.021 14.6 0.9 1.7 1 0 0 1 1 1 1 C-terminus of AA_permease DUF2427 PF10348.4 ETS76068.1 - 0.049 13.2 3.2 0.1 12.1 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4131 PF13567.1 ETS76068.1 - 0.2 11.0 4.8 3.5 6.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1640 PF07798.6 ETS76069.1 - 1.5e-12 47.9 5.8 1.5e-12 47.9 4.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 ETS76070.1 - 9.4e-18 63.8 10.3 9.4e-18 63.8 7.2 2.2 2 1 0 2 2 2 1 cwf21 domain D123 PF07065.9 ETS76071.1 - 1.6e-81 273.7 0.0 6.6e-81 271.6 0.0 1.8 1 1 0 1 1 1 1 D123 Voldacs PF03517.8 ETS76071.1 - 0.0067 16.2 0.2 0.0067 16.2 0.2 2.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Sigma70_ner PF04546.8 ETS76071.1 - 0.88 9.1 10.7 2.6 7.5 1.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop25 PF09805.4 ETS76071.1 - 2.2 8.3 7.4 1 9.4 0.3 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.7 ETS76071.1 - 5.3 4.8 14.1 2.4 5.9 1.8 2.0 2 0 0 2 2 2 0 Nop14-like family Amidohydro_4 PF13147.1 ETS76072.1 - 1.9e-14 54.3 7.9 4.2e-13 49.9 2.8 3.5 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS76072.1 - 9.8e-10 38.5 4.0 1.4e-08 34.7 0.0 2.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 ETS76072.1 - 2.2e-08 33.7 3.7 8.9e-06 25.1 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS76072.1 - 6.4e-06 25.8 0.0 4e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Response_reg PF00072.19 ETS76073.1 - 2.2e-19 69.5 0.0 5e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 ETS76073.1 - 1.1e-12 47.6 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS76073.1 - 9.2e-10 38.3 0.1 3.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 ETS76073.1 - 0.027 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toxin_19 PF08088.7 ETS76074.1 - 3.7 7.5 6.7 0.37 10.7 0.6 2.3 2 1 0 2 2 2 0 Conotoxin I-superfamily DUF3425 PF11905.3 ETS76075.1 - 6.2e-27 94.1 0.6 1e-26 93.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS76075.1 - 0.21 11.5 6.3 0.34 10.8 4.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.20 ETS76076.1 - 1.6e-12 47.6 0.2 1.2e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS76076.1 - 0.0052 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS76076.1 - 0.031 14.2 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding TIR-like PF10137.4 ETS76076.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Zn_clus PF00172.13 ETS76077.1 - 2.6e-07 30.4 4.5 4.9e-07 29.5 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACCA PF03255.9 ETS76077.1 - 0.15 11.5 0.1 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fasciclin PF02469.17 ETS76078.1 - 1.3e-32 112.5 0.2 1.9e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_47 PF01532.15 ETS76079.1 - 6e-129 430.6 0.0 7.5e-129 430.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SKG6 PF08693.5 ETS76079.1 - 0.024 13.9 0.9 0.044 13.1 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TipAS PF07739.8 ETS76079.1 - 0.064 13.5 0.6 0.17 12.2 0.2 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain CD34_antigen PF06365.7 ETS76079.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Autotrns_rpt PF12951.2 ETS76079.1 - 1.4 8.6 8.7 3.8 7.2 2.6 2.6 2 0 0 2 2 2 0 Autotransporter-associated beta strand repeat VSP PF03302.8 ETS76080.1 - 0.00031 19.4 0.4 0.00031 19.4 0.2 1.4 2 0 0 2 2 2 1 Giardia variant-specific surface protein SSP160 PF06933.6 ETS76080.1 - 0.63 7.9 12.3 0.74 7.7 8.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF822 PF05687.8 ETS76080.1 - 1.8 8.9 4.7 2.9 8.2 3.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Fringe PF02434.11 ETS76082.1 - 1.9e-07 30.5 0.0 4e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 ETS76082.1 - 0.011 15.4 2.2 0.027 14.1 1.5 1.7 1 0 0 1 1 1 0 PAN domain Beta-lactamase PF00144.19 ETS76083.1 - 3.1e-48 164.4 0.0 6e-48 163.5 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 ETS76083.1 - 1.9e-12 46.9 0.1 3.4e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Abhydrolase_6 PF12697.2 ETS76084.1 - 4.9e-25 88.7 0.1 6.5e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76084.1 - 4.9e-11 42.5 0.0 2.1e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76084.1 - 5.3e-11 42.5 0.1 3.9e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS76084.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 ETS76084.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 ETS76084.1 - 0.17 11.2 0.0 0.59 9.4 0.0 1.8 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cu-oxidase_2 PF07731.9 ETS76085.1 - 4e-23 81.4 5.4 6.5e-21 74.2 2.4 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS76085.1 - 5.3e-18 64.8 0.2 1.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS76085.1 - 4.9e-06 26.5 0.0 3.7e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase CMAS PF02353.15 ETS76087.1 - 4.5e-62 209.6 0.0 5.7e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 ETS76087.1 - 3.5e-12 46.3 0.0 6.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76087.1 - 7.8e-07 29.4 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS76087.1 - 8.8e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS76087.1 - 1.6e-05 24.8 0.0 0.00029 20.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76087.1 - 2.6e-05 24.7 0.0 7.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76087.1 - 0.00055 19.5 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76087.1 - 0.00097 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76087.1 - 0.0026 18.2 0.0 0.006 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 ETS76087.1 - 0.003 16.8 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 ETS76087.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_2 PF12796.2 ETS76088.1 - 1.1e-28 99.4 0.0 1.3e-13 51.0 0.5 4.0 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76088.1 - 3.7e-20 70.6 11.4 8.1e-08 31.7 0.6 8.7 7 2 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 ETS76088.1 - 6.2e-20 71.1 2.5 1.4e-06 28.5 0.0 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76088.1 - 6.6e-20 70.6 6.9 6.5e-09 35.7 1.1 6.7 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76088.1 - 1.9e-19 67.7 5.4 3.6e-05 23.6 0.1 7.7 8 0 0 8 8 8 5 Ankyrin repeat TipAS PF07739.8 ETS76088.1 - 0.019 15.2 0.4 0.04 14.2 0.3 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF1843 PF08898.5 ETS76088.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Ank_2 PF12796.2 ETS76089.1 - 2.4e-14 53.4 0.0 9.5e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS76089.1 - 2e-13 50.0 0.1 2.5e-07 30.7 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76089.1 - 1.1e-12 48.0 0.0 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS76089.1 - 1.1e-07 31.2 0.0 0.0024 17.5 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETS76089.1 - 5.3e-06 26.1 0.0 0.37 11.1 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat DUF4265 PF14085.1 ETS76089.1 - 0.07 12.8 0.0 0.45 10.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4265) GFA PF04828.9 ETS76092.1 - 1.2e-06 28.3 0.4 1.2e-06 28.3 0.3 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 ETS76092.1 - 0.0042 16.5 1.8 0.0042 16.5 1.3 2.2 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain DUF1049 PF06305.6 ETS76094.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) AJAP1_PANP_C PF15298.1 ETS76094.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF1191 PF06697.7 ETS76094.1 - 0.031 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 ETS76094.1 - 0.034 13.4 0.0 0.034 13.4 0.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HET PF06985.6 ETS76095.1 - 8.6e-30 103.7 0.0 1.3e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS76098.1 - 2.9e-34 117.2 0.4 1.3e-11 44.6 0.0 6.3 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 ETS76098.1 - 3.8e-25 88.5 0.0 7.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 ETS76098.1 - 4.4e-22 78.0 3.4 3.4e-06 27.4 0.0 8.5 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.25 ETS76098.1 - 1.6e-21 74.9 5.6 1.2e-07 31.1 0.0 7.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 ETS76098.1 - 6.6e-20 70.6 3.2 8.3e-06 25.8 0.0 8.7 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 ETS76098.1 - 6.2e-18 64.7 0.0 1.6e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 ETS76098.1 - 1.4e-15 55.7 5.9 0.0023 17.9 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeat Sel1 PF08238.7 ETS76098.1 - 0.0092 16.5 0.0 0.12 13.0 0.0 2.8 2 0 0 2 2 2 1 Sel1 repeat HeLo PF14479.1 ETS76099.1 - 1.2e-15 57.7 0.0 2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 ETS76099.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SnoaL_4 PF13577.1 ETS76100.1 - 8.2e-11 41.9 0.0 9.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain PrpF PF04303.8 ETS76101.1 - 1e-64 218.5 5.2 1.2e-64 218.4 3.6 1.0 1 0 0 1 1 1 1 PrpF protein PS-DH PF14765.1 ETS76101.1 - 0.00097 18.3 1.8 0.0034 16.5 0.2 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase Mito_carr PF00153.22 ETS76102.1 - 7.5e-25 86.4 7.6 2.4e-10 39.9 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.15 ETS76103.1 - 7.2e-164 545.6 0.0 2.1e-163 544.1 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS76103.1 - 1.4e-39 135.2 0.0 2.5e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Sporozoite_P67 PF05642.6 ETS76105.1 - 0.0099 13.7 6.7 0.015 13.2 4.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TEX19 PF15553.1 ETS76105.1 - 0.26 11.1 1.7 0.62 9.9 1.2 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 Menin PF05053.8 ETS76105.1 - 1.7 6.6 13.1 2.9 5.9 9.1 1.3 1 0 0 1 1 1 0 Menin Zip PF02535.17 ETS76106.1 - 9.2e-30 103.7 13.3 4.2e-27 95.0 9.2 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter TauE PF01925.14 ETS76106.1 - 0.023 14.1 0.3 0.023 14.1 0.2 2.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Endonuclease_NS PF01223.18 ETS76107.1 - 5.3e-61 205.8 0.0 6.5e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2477 PF10631.4 ETS76107.1 - 0.19 11.9 0.8 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) WD40 PF00400.27 ETS76108.1 - 3e-47 156.8 19.1 7.2e-08 32.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETS76108.1 - 0.0085 15.8 0.1 1.4 8.6 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETS76108.1 - 0.024 13.3 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like MBOAT PF03062.14 ETS76109.1 - 2.3e-23 82.8 15.8 2.3e-23 82.8 11.0 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 ETS76109.1 - 7.9e-06 25.8 2.0 7.9e-06 25.8 1.4 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RCC_reductase PF06405.6 ETS76109.1 - 0.0028 16.6 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) MFS_1 PF07690.11 ETS76110.1 - 4.9e-16 58.3 40.0 5.9e-08 31.8 5.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 ETS76110.1 - 5.8e-06 24.9 8.3 2.3e-05 22.9 1.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein bZIP_1 PF00170.16 ETS76111.1 - 9.5e-06 25.4 7.7 1.8e-05 24.5 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS76111.1 - 0.13 12.0 6.4 0.38 10.6 4.4 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF4496 PF14908.1 ETS76111.1 - 0.98 9.3 3.8 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) BAF1_ABF1 PF04684.8 ETS76111.1 - 2.9 6.6 17.4 4.7 5.9 12.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Stm1_N PF09598.5 ETS76112.1 - 1.5e-12 48.0 0.8 1.5e-12 48.0 0.5 4.1 3 1 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 ETS76112.1 - 0.00015 22.2 6.7 0.00015 22.2 4.7 2.7 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family mIF3 PF14877.1 ETS76112.1 - 0.016 14.5 0.8 0.032 13.6 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Dppa2_A PF14049.1 ETS76113.1 - 0.018 14.9 1.8 0.038 13.8 1.3 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates BAF1_ABF1 PF04684.8 ETS76113.1 - 3.9 6.2 8.3 5.3 5.7 5.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-C2H2 PF00096.21 ETS76114.1 - 5.6e-27 92.4 58.7 1.8e-05 24.7 0.2 11.0 10 1 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS76114.1 - 2.7e-25 86.7 53.1 0.0031 17.7 0.6 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS76114.1 - 8e-14 51.1 50.1 1.6e-06 28.0 0.8 10.0 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS76114.1 - 5e-07 29.6 31.6 0.11 12.6 0.3 10.6 11 0 0 11 11 11 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS76114.1 - 2.7e-06 27.3 23.6 1.4 9.2 0.1 9.1 10 0 0 10 10 10 3 Zinc-finger of C2H2 type CHORD PF04968.7 ETS76114.1 - 0.00035 20.7 22.9 0.2 11.8 0.1 6.7 4 2 3 7 7 7 2 CHORD zf-C2H2_6 PF13912.1 ETS76114.1 - 0.31 10.9 24.3 0.21 11.5 0.3 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger IBR PF01485.16 ETS76114.1 - 0.74 9.7 22.7 15 5.5 0.0 5.6 2 1 1 3 3 3 0 IBR domain Ogr_Delta PF04606.7 ETS76114.1 - 4.8 6.9 11.9 7.2 6.3 0.1 4.7 4 1 1 5 5 5 0 Ogr/Delta-like zinc finger RNA_pol_Rpb6 PF01192.17 ETS76115.1 - 9.1e-24 82.9 0.3 9.1e-24 82.9 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 Innate_immun PF12782.2 ETS76115.1 - 0.012 14.8 1.6 0.016 14.4 1.1 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family eIF3_subunit PF08597.5 ETS76115.1 - 0.091 12.3 4.8 0.12 11.8 3.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SDA1 PF05285.7 ETS76115.1 - 0.16 11.2 7.2 0.21 10.8 5.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS76115.1 - 3 5.6 12.3 3.8 5.3 8.5 1.0 1 0 0 1 1 1 0 Nop14-like family Esterase PF00756.15 ETS76116.1 - 3.7e-54 183.7 0.0 4.3e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETS76116.1 - 3.8e-08 33.1 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETS76116.1 - 5.4e-07 29.0 0.1 1.8e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 ETS76116.1 - 4.5e-06 26.7 0.0 5.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS76116.1 - 0.0004 19.6 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 ETS76116.1 - 0.0082 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 ETS76116.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 ETS76116.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 ETS76116.1 - 0.053 13.0 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 ETS76116.1 - 0.058 12.9 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.6 ETS76116.1 - 0.14 10.9 0.1 0.57 8.9 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Afi1 PF07792.7 ETS76117.1 - 1.3e-64 216.5 0.2 2.5e-64 215.6 0.2 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 ETS76117.1 - 5.4e-36 122.7 0.0 1e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 ETS76117.1 - 1.4e-08 33.6 0.0 0.0067 14.9 0.0 3.8 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 ETS76117.1 - 0.046 13.0 0.0 0.66 9.2 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Ycf1 PF05758.7 ETS76117.1 - 0.19 9.3 0.4 0.26 8.9 0.3 1.1 1 0 0 1 1 1 0 Ycf1 Astro_capsid PF03115.9 ETS76117.1 - 0.21 9.8 0.4 0.29 9.3 0.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 ETS76117.1 - 1.3 8.6 17.5 2.5 7.7 12.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 ETS76117.1 - 1.8 7.8 11.9 2.9 7.1 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) EF-hand_6 PF13405.1 ETS76118.1 - 3.9e-12 44.9 0.9 1e-05 24.9 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 ETS76118.1 - 4.4e-10 38.1 1.5 0.00065 18.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETS76118.1 - 1e-08 35.1 0.0 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 ETS76118.1 - 7.2e-07 28.2 5.7 0.00088 18.5 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 ETS76118.1 - 3.4e-05 23.3 0.2 0.21 11.2 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 ETS76118.1 - 8e-05 22.4 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain TPR_11 PF13414.1 ETS76119.1 - 2.5e-51 171.2 20.8 6.5e-23 80.1 1.4 6.3 3 2 3 6 6 6 4 TPR repeat TPR_1 PF00515.23 ETS76119.1 - 2.7e-42 140.6 18.7 3.6e-09 35.8 0.1 9.2 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS76119.1 - 2.2e-36 120.8 20.4 2.3e-06 27.0 0.1 8.8 8 1 1 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 ETS76119.1 - 1.7e-29 101.3 2.4 5.9e-29 99.5 1.6 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 ETS76119.1 - 4.8e-25 87.6 17.2 3.4e-09 37.1 0.0 6.7 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS76119.1 - 8.2e-24 83.7 13.6 3e-08 33.8 0.0 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETS76119.1 - 1e-21 75.3 12.3 5e-06 26.6 0.2 7.8 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS76119.1 - 9.9e-21 72.1 12.5 0.00024 21.0 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76119.1 - 6.2e-20 69.4 12.8 0.0011 18.6 0.0 8.1 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS76119.1 - 6.8e-19 67.5 13.0 5.8e-07 29.3 0.0 5.7 2 2 4 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 ETS76119.1 - 9.4e-18 64.1 7.9 1.1e-10 41.5 0.1 4.1 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETS76119.1 - 2e-14 53.2 10.7 2.3e-05 24.1 0.1 5.1 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS76119.1 - 1.4e-11 43.2 9.0 0.12 12.2 0.0 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 ETS76119.1 - 4.3e-09 35.8 9.1 0.00077 18.5 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS76119.1 - 5.1e-08 32.8 17.4 0.0046 17.3 0.1 7.4 8 1 0 8 8 6 2 Tetratricopeptide repeat BTAD PF03704.12 ETS76119.1 - 5.6e-06 26.7 6.0 0.012 15.8 0.1 4.2 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 ETS76119.1 - 1.2e-05 25.3 3.6 0.29 11.6 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 ETS76119.1 - 5.8e-05 23.3 0.6 0.11 12.7 0.0 3.5 2 1 0 2 2 2 1 Alkyl sulfatase dimerisation NARP1 PF12569.3 ETS76119.1 - 6.5e-05 21.8 5.3 0.057 12.1 0.6 3.2 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 ETS76119.1 - 0.0001 22.3 9.0 0.83 9.8 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS76119.1 - 0.00034 20.4 12.6 0.97 9.4 0.5 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 ETS76119.1 - 0.0012 17.6 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 ETS76119.1 - 0.0016 18.3 4.0 7.9 6.4 0.1 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 ETS76119.1 - 0.0016 18.3 7.2 0.12 12.3 0.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 ETS76119.1 - 0.002 16.9 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Coatomer_E PF04733.9 ETS76119.1 - 0.0043 16.2 1.2 0.076 12.1 0.0 2.8 3 1 0 3 3 3 1 Coatomer epsilon subunit SHNi-TPR PF10516.4 ETS76119.1 - 0.045 12.9 0.2 10 5.4 0.0 3.2 2 0 0 2 2 2 0 SHNi-TPR Snurportin1 PF11538.3 ETS76119.1 - 3.5 7.4 6.6 0.96 9.2 0.1 2.9 3 0 0 3 3 2 0 Snurportin1 GSH_synth_ATP PF03917.12 ETS76120.1 - 4.5e-111 371.0 0.0 5.5e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 ETS76120.1 - 8.9e-30 102.8 0.0 1.6e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Condensin2nSMC PF12422.3 ETS76120.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit HET PF06985.6 ETS76121.1 - 1.1e-30 106.6 0.0 2.3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 ETS76122.1 - 1.2e-44 152.2 0.2 2.7e-44 151.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS76122.1 - 2.3e-15 56.1 0.1 8.8e-15 54.3 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Caldesmon PF02029.10 ETS76123.1 - 0.016 13.6 0.5 0.018 13.4 0.4 1.0 1 0 0 1 1 1 0 Caldesmon Alk_phosphatase PF00245.15 ETS76124.1 - 6.6e-104 347.9 0.0 8.9e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 ETS76124.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Ribosomal_60s PF00428.14 ETS76124.1 - 0.021 15.2 0.1 0.072 13.5 0.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin PF00022.14 ETS76125.1 - 2.8e-30 105.0 0.0 6.8e-19 67.5 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 ETS76125.1 - 0.072 11.6 0.0 0.25 9.8 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein PROL5-SMR PF15621.1 ETS76125.1 - 5.9 7.3 7.6 29 5.1 5.4 2.0 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Myb_DNA-bind_6 PF13921.1 ETS76126.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain ATP_transf PF09830.4 ETS76127.1 - 1.3e-15 56.8 0.0 2.9e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 ETS76127.1 - 0.011 16.2 0.1 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 HIT domain SurE PF01975.12 ETS76128.1 - 8.3e-27 93.7 0.0 1.2e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE GATase PF00117.23 ETS76129.1 - 4.2e-09 36.1 0.2 5.9e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETS76129.1 - 0.068 12.6 0.3 0.13 11.6 0.2 1.6 1 1 0 1 1 1 0 Peptidase C26 NicO PF03824.11 ETS76130.1 - 1.1e-62 211.9 9.5 1.5e-62 211.4 6.6 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.16 ETS76131.1 - 2.3e-49 168.0 0.2 5.7e-33 114.1 0.1 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease EF-hand_8 PF13833.1 ETS76132.1 - 1.2e-13 50.4 0.0 1.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS76132.1 - 1.2e-12 46.1 0.8 6.8e-10 37.5 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 ETS76132.1 - 7.2e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 ETS76132.1 - 7.3e-08 31.4 0.4 8.5e-06 24.8 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETS76132.1 - 1.3e-06 27.7 0.1 0.0012 18.5 0.1 2.4 1 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETS76132.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 ETS76132.1 - 0.014 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain UPF0154 PF03672.8 ETS76132.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) HrpB2 PF09487.5 ETS76132.1 - 0.11 12.6 0.3 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) MFS_1 PF07690.11 ETS76134.1 - 1.6e-33 115.8 23.9 1.6e-33 115.8 16.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2422 PF10337.4 ETS76134.1 - 0.57 8.9 4.0 5.4 5.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Amidase PF01425.16 ETS76135.1 - 1.4e-101 340.5 0.0 1.7e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 ETS76136.1 - 1.5e-19 69.8 1.1 2.6e-19 69.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76136.1 - 2.3e-08 33.7 12.7 4.2e-08 32.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 ETS76137.1 - 1.4e-114 383.9 0.2 2.1e-114 383.3 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1295 PF06966.7 ETS76138.1 - 2.9e-30 105.3 0.0 3.9e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 ETS76138.1 - 3.4e-06 26.8 0.0 9.2e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 ETS76138.1 - 0.0022 18.1 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS76138.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 ETS76138.1 - 0.031 12.8 0.0 0.074 11.5 0.0 1.6 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1656 PF07869.7 ETS76138.1 - 0.11 12.3 2.4 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Clathrin PF00637.15 ETS76139.1 - 1.8e-16 60.0 2.0 3e-15 56.0 0.1 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 ETS76139.1 - 1.2e-05 24.9 0.4 3e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS76139.1 - 0.00073 19.2 0.9 0.003 17.2 0.6 2.0 1 1 0 1 1 1 1 zinc-RING finger domain WD40 PF00400.27 ETS76139.1 - 0.0037 17.0 0.4 10 6.1 0.0 3.8 4 1 0 4 4 4 2 WD domain, G-beta repeat C1_1 PF00130.17 ETS76139.1 - 0.096 12.4 0.6 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_7 PF13176.1 ETS76139.1 - 0.1 12.4 0.9 0.56 10.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc1 PF12859.2 ETS76140.1 - 1.8e-25 89.1 0.1 7.4e-25 87.1 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 ETS76140.1 - 2.6e-05 24.1 0.9 0.015 15.5 0.0 4.1 4 0 0 4 4 4 2 Proteasome/cyclosome repeat DUF3533 PF12051.3 ETS76141.1 - 1.9e-112 375.7 19.1 2.2e-112 375.5 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 ETS76141.1 - 0.56 9.8 7.0 0.61 9.7 0.0 3.1 3 0 0 3 3 3 0 CDR ABC transporter Aa_trans PF01490.13 ETS76142.1 - 2.6e-23 82.1 25.3 3.2e-23 81.8 17.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YbjM PF11045.3 ETS76142.1 - 0.016 14.9 6.2 1.5 8.5 1.6 2.8 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae DUF2208 PF09973.4 ETS76142.1 - 0.08 12.1 1.2 0.14 11.4 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Peptidase_C97 PF05903.9 ETS76143.1 - 6.5e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 ETS76143.1 - 0.13 12.2 0.8 0.31 11.0 0.6 1.7 1 1 0 1 1 1 0 Lecithin retinol acyltransferase WD40 PF00400.27 ETS76145.1 - 4.8e-37 124.5 3.4 6.7e-09 35.3 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 ETS76145.1 - 4.8e-07 28.2 2.6 0.19 9.8 0.0 4.6 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Trypsin_2 PF13365.1 ETS76145.1 - 0.0011 18.9 0.1 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Arena_nucleocap PF00843.12 ETS76145.1 - 0.015 13.2 4.2 0.22 9.3 0.0 3.4 2 1 2 4 4 4 0 Arenavirus nucleocapsid protein FmdE PF02663.9 ETS76145.1 - 0.027 14.3 0.0 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon VID27 PF08553.5 ETS76145.1 - 0.088 11.0 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein PDDEXK_1 PF12705.2 ETS76145.1 - 0.2 11.0 0.1 7.9 5.7 0.0 2.5 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Glyco_hydro_31 PF01055.21 ETS76146.1 - 2.3e-83 280.4 0.1 3e-83 280.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS76146.1 - 7.3e-13 48.1 0.0 2.9e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like EF-hand_4 PF12763.2 ETS76147.1 - 2e-26 91.7 0.0 7.2e-14 51.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 ETS76147.1 - 0.00014 21.9 0.0 0.092 12.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.6 ETS76147.1 - 0.00048 20.1 27.0 0.00048 20.1 18.7 8.2 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 ETS76147.1 - 0.00064 18.8 0.0 0.55 9.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 ETS76147.1 - 0.0013 18.4 0.0 1.2 9.2 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain E3_binding PF02817.12 ETS76147.1 - 0.065 12.8 0.0 0.065 12.8 0.0 2.4 3 0 0 3 3 3 0 e3 binding domain CMAS PF02353.15 ETS76148.1 - 1.2e-64 218.0 0.0 1.5e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 ETS76148.1 - 3.7e-10 39.7 0.0 1.4e-09 37.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76148.1 - 1.3e-07 32.0 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76148.1 - 0.00086 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76148.1 - 0.0037 17.7 0.0 0.0096 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76148.1 - 0.0046 17.5 0.0 0.025 15.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 ETS76148.1 - 0.0091 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 ETS76148.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 ETS76148.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 ETS76148.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain G-patch_2 PF12656.2 ETS76149.1 - 5.6e-18 64.5 0.2 3.5e-17 62.0 0.1 2.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site HSA PF07529.8 ETS76150.1 - 1.1e-18 66.8 1.9 1.1e-18 66.8 1.3 5.7 6 0 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.1 ETS76150.1 - 3.4e-14 52.6 0.8 1e-13 51.1 0.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS76150.1 - 0.025 14.6 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain WD40 PF00400.27 ETS76151.1 - 1.2e-16 59.8 0.1 0.00014 21.5 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 ETS76151.1 - 0.14 11.8 0.0 3.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Dicty_REP PF05086.7 ETS76151.1 - 0.4 8.3 2.2 0.55 7.9 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein INSIG PF07281.7 ETS76152.1 - 1.4e-37 128.9 0.7 1.8e-37 128.5 0.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) LON PF02190.11 ETS76153.1 - 3.1e-26 92.3 0.0 5.5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 ETS76153.1 - 7.1e-14 51.4 22.3 6.6e-07 29.1 5.4 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 ETS76153.1 - 2.3e-11 43.5 28.4 1.7e-08 34.3 8.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS76153.1 - 3.6e-10 39.5 28.3 3.8e-08 33.0 9.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 ETS76153.1 - 4.8e-09 35.7 26.6 2.6e-07 30.2 8.1 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS76153.1 - 1.5e-07 31.0 20.6 3.3e-07 29.8 6.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS76153.1 - 1.6e-07 30.8 24.5 1.2e-05 24.8 9.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS76153.1 - 3.4e-05 23.4 4.4 3.4e-05 23.4 3.0 3.3 3 0 0 3 3 3 1 RING-type zinc-finger U-box PF04564.10 ETS76153.1 - 0.0017 18.2 0.1 0.0081 16.1 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-P11 PF03854.9 ETS76153.1 - 0.0023 17.3 6.3 0.0023 17.3 4.4 2.0 2 0 0 2 2 1 1 P-11 zinc finger zf-RING_4 PF14570.1 ETS76153.1 - 0.0024 17.4 6.0 0.0024 17.4 4.1 2.4 3 1 0 3 3 2 1 RING/Ubox like zinc-binding domain UPF0556 PF10572.4 ETS76153.1 - 0.067 12.3 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 zf-RING_6 PF14835.1 ETS76153.1 - 0.19 11.5 16.7 0.21 11.3 3.2 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Clr5 PF14420.1 ETS76154.1 - 1.1e-10 41.1 0.4 2.8e-10 39.9 0.1 1.9 2 0 0 2 2 2 1 Clr5 domain YEATS PF03366.11 ETS76156.1 - 5.8e-12 45.1 0.7 9.8e-12 44.4 0.5 1.3 1 0 0 1 1 1 1 YEATS family zf-RING_2 PF13639.1 ETS76156.1 - 1.2e-07 31.4 5.1 2.2e-07 30.5 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETS76156.1 - 9.3e-07 28.6 2.9 9.3e-07 28.6 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS76156.1 - 1.4e-06 27.8 3.9 3.1e-06 26.7 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS76156.1 - 1.8e-06 27.8 4.9 7.3e-06 25.9 3.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS76156.1 - 7.5e-06 25.5 8.3 3.9e-05 23.2 5.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS76156.1 - 2.2e-05 24.0 5.8 8.6e-05 22.1 4.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS76156.1 - 0.0013 18.4 3.9 0.0013 18.4 2.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 ETS76156.1 - 0.0094 15.5 3.6 3.4 7.3 0.0 3.2 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain CcmH PF03918.9 ETS76156.1 - 0.11 11.4 0.8 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Mu-like_Com PF10122.4 ETS76156.1 - 0.13 11.3 1.4 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-Apc11 PF12861.2 ETS76156.1 - 0.37 10.6 5.8 7.8 6.4 2.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETS76156.1 - 0.55 10.3 8.2 2.5 8.2 3.5 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 ETS76156.1 - 1.4 8.5 7.2 4.3 6.9 5.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit BRCT PF00533.21 ETS76158.1 - 2.2e-07 30.9 0.0 4.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain vMSA PF00695.14 ETS76159.1 - 4.6 6.3 5.4 7.9 5.5 3.8 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Extensin_2 PF04554.8 ETS76159.1 - 6.9 6.6 14.3 22 4.9 9.9 1.9 1 1 0 1 1 1 0 Extensin-like region NACHT PF05729.7 ETS76160.1 - 8.5e-07 28.7 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 ETS76160.1 - 8.7e-06 25.3 0.2 0.00066 19.3 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 ETS76160.1 - 2.8e-05 23.9 0.0 0.0045 17.1 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.1 ETS76160.1 - 0.00013 22.1 0.0 0.0018 18.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 ETS76160.1 - 0.00089 19.5 0.0 0.0074 16.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS76160.1 - 0.0073 16.5 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS76160.1 - 0.019 14.9 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 ETS76160.1 - 0.033 12.6 2.3 0.42 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 ETS76160.1 - 0.033 13.1 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 ETS76160.1 - 0.039 12.8 0.0 0.78 8.5 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain Ank_4 PF13637.1 ETS76160.1 - 0.061 13.8 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RNA_helicase PF00910.17 ETS76160.1 - 0.064 13.4 0.0 0.26 11.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 ETS76160.1 - 0.074 12.9 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bromo_TP PF07524.8 ETS76160.1 - 0.12 12.1 0.0 0.49 10.1 0.0 2.1 1 0 0 1 1 1 0 Bromodomain associated CbiA PF01656.18 ETS76160.1 - 0.48 9.8 2.3 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribonuc_L-PSP PF01042.16 ETS76161.1 - 2.3e-16 59.6 0.1 1.3e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 Endoribonuclease L-PSP Dioxygenase_C PF00775.16 ETS76161.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase Methyltransf_3 PF01596.12 ETS76162.1 - 1.4e-12 47.1 0.0 1.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETS76162.1 - 1.1e-11 45.4 0.0 1.8e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain APH PF01636.18 ETS76163.1 - 1.6e-17 64.0 0.5 2.7e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS76163.1 - 0.00052 19.2 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase SRP54 PF00448.17 ETS76164.1 - 9.6e-76 253.6 1.8 1.8e-75 252.7 0.6 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 ETS76164.1 - 1.4e-25 89.5 3.0 1.4e-25 89.5 2.1 3.7 4 1 1 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 ETS76164.1 - 2.6e-14 53.0 0.3 7.5e-14 51.5 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 ETS76164.1 - 1.4e-08 34.3 0.2 4.5e-08 32.7 0.1 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 ETS76164.1 - 3.9e-07 30.0 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 ETS76164.1 - 1.1e-05 25.1 0.0 3.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETS76164.1 - 2.7e-05 24.9 0.0 6.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 ETS76164.1 - 7.7e-05 22.1 0.1 0.0003 20.2 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 ETS76164.1 - 0.00063 19.0 2.0 2.3 7.3 0.1 3.5 3 1 0 4 4 4 1 Signal recognition particle receptor beta subunit AAA_31 PF13614.1 ETS76164.1 - 0.001 19.0 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 ETS76164.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 ETS76164.1 - 0.002 18.1 0.1 0.0053 16.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain ArgK PF03308.11 ETS76164.1 - 0.0021 16.8 1.3 0.0052 15.5 0.2 2.2 2 1 0 2 2 2 1 ArgK protein ATP_bind_1 PF03029.12 ETS76164.1 - 0.0022 17.5 0.3 0.042 13.3 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 ETS76164.1 - 0.0023 16.6 0.4 0.021 13.4 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 ETS76164.1 - 0.0026 17.8 0.0 0.0095 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS76164.1 - 0.0044 16.1 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 ETS76164.1 - 0.0056 16.0 0.0 0.017 14.4 0.0 1.9 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 ETS76164.1 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS76164.1 - 0.018 14.7 0.3 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 ETS76164.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 ETS76164.1 - 0.031 13.3 0.1 0.066 12.2 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arf PF00025.16 ETS76164.1 - 0.058 12.6 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 ETS76164.1 - 0.067 13.3 0.3 0.27 11.4 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AA_permease PF00324.16 ETS76165.1 - 7.7e-30 103.6 29.1 3.1e-29 101.6 20.2 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76165.1 - 4.5e-15 55.1 25.0 6.8e-15 54.5 17.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF92 PF01940.11 ETS76165.1 - 0.061 12.4 0.0 0.061 12.4 0.0 2.6 3 0 0 3 3 3 0 Integral membrane protein DUF92 7tm_7 PF08395.7 ETS76165.1 - 1.3 7.9 8.2 0.11 11.4 2.1 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor Pkinase PF00069.20 ETS76166.1 - 4.3e-21 75.2 0.0 1.6e-20 73.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76166.1 - 3.6e-14 52.4 0.0 6.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS76166.1 - 0.099 11.4 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cellulase PF00150.13 ETS76167.1 - 2.9e-50 171.0 2.2 3.5e-50 170.7 1.5 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 ETS76168.1 - 1.9e-44 151.7 0.0 2.5e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76168.1 - 1.8e-22 79.6 0.0 2.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BAG PF02179.11 ETS76168.1 - 5e-05 23.3 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 BAG domain Kdo PF06293.9 ETS76168.1 - 9.3e-05 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS76168.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 ETS76169.1 - 0.00026 20.1 0.0 0.026 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 ETS76169.1 - 0.0035 16.5 0.0 0.018 14.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Git3 PF11710.3 ETS76171.1 - 1.1e-22 80.5 13.6 2.8e-22 79.2 9.4 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 ETS76171.1 - 1.2e-06 27.8 10.1 1.8e-06 27.2 7.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 ETS76171.1 - 0.00026 20.6 0.0 0.00077 19.1 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 ETS76171.1 - 0.0026 16.7 11.0 0.0039 16.1 7.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyco_hydro_31 PF01055.21 ETS76172.1 - 1.2e-137 459.3 3.9 1.5e-137 459.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rpp20 PF12328.3 ETS76173.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Ribonucleas_3_3 PF14622.1 ETS76173.1 - 0.16 11.9 0.4 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease-III-like Glyco_transf_15 PF01793.11 ETS76175.1 - 1.7e-113 378.9 8.9 2.1e-113 378.6 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Gly_transf_sug PF04488.10 ETS76176.1 - 7.7e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETS76176.1 - 0.00023 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 ETS76176.1 - 0.00043 18.9 0.1 0.0013 17.2 0.0 1.7 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain HET PF06985.6 ETS76177.1 - 8.1e-21 74.6 0.0 1.7e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS76179.1 - 3.1e-37 128.0 22.5 3.1e-37 128.0 15.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC12 PF06645.8 ETS76179.1 - 1.4 8.7 4.8 2.3 8.0 0.3 3.3 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HpcH_HpaI PF03328.9 ETS76180.1 - 1.4e-35 122.2 0.4 1.6e-35 121.9 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 ETS76180.1 - 0.0015 17.5 0.1 0.063 12.1 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ribonuc_L-PSP PF01042.16 ETS76181.1 - 1.5e-22 79.6 0.0 1.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mg_chelatase_2 PF13335.1 ETS76181.1 - 0.056 13.8 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 2OG-FeII_Oxy PF03171.15 ETS76182.1 - 3e-11 43.4 0.0 5.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS76182.1 - 3.7e-08 33.9 0.0 8.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.13 ETS76183.1 - 4.3e-20 71.6 0.6 8.4e-20 70.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 ETS76183.1 - 4.9e-06 26.5 12.7 0.0094 16.2 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS76183.1 - 9.4e-06 25.6 14.6 0.0041 17.3 1.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 ETS76183.1 - 0.0018 18.4 3.4 0.43 10.8 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 ETS76183.1 - 0.0058 16.8 5.9 0.13 12.6 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS76183.1 - 0.018 15.1 3.0 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS76183.1 - 0.065 13.1 2.5 2.5 8.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met2 PF12907.2 ETS76183.1 - 0.14 12.1 0.9 8.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_2 PF12756.2 ETS76183.1 - 0.95 9.6 6.1 7.9 6.6 0.4 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) IncA PF04156.9 ETS76184.1 - 0.0012 18.4 4.7 0.0016 18.0 3.3 1.2 1 0 0 1 1 1 1 IncA protein DUF2570 PF10828.3 ETS76184.1 - 0.0084 15.6 5.5 0.015 14.8 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF342 PF03961.8 ETS76184.1 - 0.015 13.7 6.9 0.019 13.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HAUS-augmin3 PF14932.1 ETS76184.1 - 0.016 14.4 5.8 0.025 13.7 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Lebercilin PF15619.1 ETS76184.1 - 0.026 13.9 11.7 0.041 13.2 8.1 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Nsp1_C PF05064.8 ETS76184.1 - 0.058 13.0 4.0 0.093 12.3 2.7 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region TMPIT PF07851.8 ETS76184.1 - 0.066 12.2 7.2 0.09 11.8 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.11 ETS76184.1 - 0.079 13.1 6.7 0.2 11.9 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 HSBP1 PF06825.7 ETS76184.1 - 0.083 12.4 0.7 0.44 10.1 0.1 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TMF_DNA_bd PF12329.3 ETS76184.1 - 0.14 11.9 13.2 0.35 10.7 8.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 ETS76184.1 - 0.15 9.9 6.5 0.16 9.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 ETS76184.1 - 0.15 11.5 6.5 0.24 10.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4071 PF13281.1 ETS76184.1 - 0.38 9.5 6.7 0.47 9.2 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Noc2 PF03715.8 ETS76184.1 - 0.41 9.4 3.7 0.63 8.8 2.6 1.3 1 0 0 1 1 1 0 Noc2p family OEP PF02321.13 ETS76184.1 - 0.45 10.0 5.4 11 5.5 0.0 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein ADIP PF11559.3 ETS76184.1 - 0.81 9.5 15.6 2.3 8.0 4.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 ETS76184.1 - 0.91 8.4 10.1 1.1 8.1 7.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Striatin PF08232.7 ETS76184.1 - 1.4 9.2 11.5 2.3 8.5 3.2 2.4 1 1 1 2 2 2 0 Striatin family DUF2968 PF11180.3 ETS76184.1 - 4 6.7 11.3 6.1 6.1 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_23 PF13476.1 ETS76184.1 - 4.4 7.5 10.1 7.5 6.8 7.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.7 ETS76184.1 - 4.8 7.2 5.8 39 4.3 0.3 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat SlyX PF04102.7 ETS76184.1 - 6.8 7.1 6.6 8.3 6.8 2.5 2.4 1 1 1 2 2 2 0 SlyX Amidohydro_2 PF04909.9 ETS76185.1 - 2e-43 148.9 0.2 2.5e-43 148.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SnoaL_4 PF13577.1 ETS76186.1 - 0.0036 17.1 0.2 0.0067 16.3 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 ETS76186.1 - 0.12 12.7 0.1 0.18 12.2 0.1 1.3 1 1 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.2 ETS76187.1 - 2.8e-30 105.8 0.0 3.3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76187.1 - 1e-20 74.0 0.2 1.5e-20 73.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76187.1 - 1.6e-12 47.4 0.3 4.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS76187.1 - 2.1e-09 37.1 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS76187.1 - 1.5e-05 24.3 0.1 0.1 11.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.9 ETS76187.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Ser_hydrolase PF06821.8 ETS76187.1 - 0.00021 20.9 0.1 0.052 13.1 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 ETS76187.1 - 0.00022 20.7 0.7 2.1 7.7 0.1 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DUF1057 PF06342.7 ETS76187.1 - 0.0022 16.8 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 ETS76187.1 - 0.0039 17.4 0.2 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain DLH PF01738.13 ETS76187.1 - 0.0091 15.2 0.0 0.25 10.6 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 ETS76187.1 - 0.013 13.8 2.5 0.62 8.3 0.7 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.5 ETS76187.1 - 0.024 14.5 0.0 0.074 12.9 0.0 1.7 1 1 0 1 1 1 0 TAP-like protein DUF2305 PF10230.4 ETS76187.1 - 0.032 13.6 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 ETS76187.1 - 0.036 13.6 0.3 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.2 ETS76187.1 - 0.044 12.6 0.6 0.18 10.6 0.4 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 ETS76187.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) CoA_transf_3 PF02515.12 ETS76189.1 - 4.6e-31 107.5 0.0 5.6e-30 103.9 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III UPF0262 PF06793.7 ETS76189.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Dioxygenase_C PF00775.16 ETS76190.1 - 2.5e-48 163.7 0.0 3.2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS76190.1 - 2.8e-13 49.6 0.0 4.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 ETS76190.1 - 2.6e-06 27.3 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 ETS76190.1 - 7.6e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) MG1 PF11974.3 ETS76190.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain DUF2824 PF11039.3 ETS76190.1 - 0.096 12.4 0.0 0.41 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2824) DEAD PF00270.24 ETS76191.1 - 9.3e-41 139.1 0.4 2.4e-40 137.8 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS76191.1 - 4e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 ETS76191.1 - 0.0048 16.2 0.5 0.0085 15.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain ResIII PF04851.10 ETS76191.1 - 0.016 15.0 0.1 0.065 13.0 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETS76191.1 - 0.016 14.7 0.7 0.038 13.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS76191.1 - 0.02 14.6 0.2 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 ETS76191.1 - 0.046 13.4 0.5 0.14 11.8 0.0 2.1 3 1 0 3 3 3 0 Flavivirus DEAD domain AAA_22 PF13401.1 ETS76191.1 - 0.09 12.9 1.1 0.42 10.7 0.8 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 ETS76192.1 - 2.5e-71 239.2 1.5 4.7e-71 238.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 ETS76192.1 - 2.9e-10 39.4 0.0 6.9e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 ETS76192.1 - 1.6e-09 37.6 3.2 7.8e-08 32.2 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS76192.1 - 1.7e-08 34.3 1.2 1.7e-08 34.3 0.8 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 ETS76192.1 - 0.00014 21.8 0.0 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 ETS76192.1 - 0.0026 17.4 1.2 0.0026 17.4 0.8 2.7 3 1 0 3 3 3 1 DBF zinc finger Myb_CC_LHEQLE PF14379.1 ETS76192.1 - 0.037 13.5 3.1 0.27 10.8 2.1 2.3 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2_4 PF13894.1 ETS76192.1 - 0.053 13.8 2.1 3.3 8.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pox_P21 PF05313.7 ETS76192.1 - 0.055 12.7 0.1 0.088 12.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF951 PF06107.6 ETS76192.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-U1 PF06220.7 ETS76192.1 - 0.11 12.0 0.8 0.27 10.8 0.6 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 ETS76192.1 - 1 9.8 6.6 2.6 8.5 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1446 PF07287.6 ETS76193.1 - 1.1e-127 425.4 0.2 1.4e-127 425.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) ADH_zinc_N PF00107.21 ETS76195.1 - 5.2e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS76195.1 - 1.5e-09 38.8 0.0 6e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS76195.1 - 3.5e-09 36.4 0.1 9.8e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.14 ETS76195.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain COG2 PF06148.6 ETS76196.1 - 3.7e-25 88.3 0.4 7.7e-25 87.3 0.3 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 ETS76196.1 - 0.00022 21.0 4.5 0.00025 20.8 0.0 2.9 3 1 0 3 3 3 1 Vps51/Vps67 COG5 PF10392.4 ETS76196.1 - 0.02 14.8 0.6 0.064 13.2 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2450 PF10475.4 ETS76196.1 - 0.042 12.7 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sigma70_ner PF04546.8 ETS76196.1 - 0.06 12.9 5.4 0.15 11.7 3.7 1.7 1 1 0 1 1 1 0 Sigma-70, non-essential region HD_4 PF13328.1 ETS76196.1 - 0.089 12.4 1.1 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 HD domain Spc7 PF08317.6 ETS76196.1 - 0.097 11.3 2.1 0.14 10.7 0.5 1.9 2 1 0 2 2 2 0 Spc7 kinetochore protein PBP1_TM PF14812.1 ETS76196.1 - 0.1 12.8 2.0 0.29 11.4 1.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE-A_C-term PF11521.3 ETS76196.1 - 0.3 11.0 4.9 0.19 11.7 0.3 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Hap4_Hap_bind PF10297.4 ETS76197.1 - 2e-09 36.9 7.1 6e-09 35.4 4.9 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 ETS76197.1 - 0.00022 21.0 9.2 0.00022 21.0 6.4 2.8 1 1 2 3 3 3 1 bZIP transcription factor CCDC144C PF14915.1 ETS76197.1 - 0.0015 17.4 4.0 0.0025 16.7 2.8 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF4482 PF14818.1 ETS76197.1 - 0.007 17.0 2.4 0.007 17.0 1.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4482) Striatin PF08232.7 ETS76197.1 - 0.012 15.9 7.3 0.047 13.9 2.2 2.5 2 0 0 2 2 2 0 Striatin family CENP-F_leu_zip PF10473.4 ETS76197.1 - 0.013 15.3 13.1 0.066 13.0 5.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 ETS76197.1 - 0.063 12.4 0.3 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETS76197.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glutaredoxin2_C PF04399.8 ETS76197.1 - 0.091 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PV-1 PF06637.6 ETS76197.1 - 0.28 9.7 9.3 2.5 6.5 2.7 2.2 1 1 1 2 2 2 0 PV-1 protein (PLVAP) IncA PF04156.9 ETS76197.1 - 0.66 9.5 9.0 1.3 8.5 6.3 1.4 1 0 0 1 1 1 0 IncA protein PspB PF06667.7 ETS76197.1 - 0.99 9.3 2.2 2.2 8.2 1.5 1.6 1 0 0 1 1 1 0 Phage shock protein B LURAP PF14854.1 ETS76197.1 - 1.8 8.2 6.0 0.26 11.0 0.9 2.0 2 0 0 2 2 2 0 Leucine rich adaptor protein DUF2066 PF09839.4 ETS76198.1 - 0.051 12.6 0.1 0.85 8.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) FAD_binding_4 PF01565.18 ETS76200.1 - 1.7e-16 59.9 1.6 7.2e-16 57.9 1.1 2.1 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS76200.1 - 3.3e-10 39.7 2.5 6.1e-10 38.8 1.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS76200.1 - 0.00045 19.4 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding RPW8 PF05659.6 ETS76202.1 - 0.015 14.8 0.1 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RIC3 PF15361.1 ETS76202.1 - 0.042 14.0 5.3 0.048 13.8 3.7 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FUSC PF04632.7 ETS76202.1 - 0.18 10.1 2.3 0.23 9.8 1.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GTPase_Cys_C PF12631.2 ETS76202.1 - 0.47 10.9 4.7 0.38 11.1 0.6 2.4 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Med9 PF07544.8 ETS76202.1 - 0.97 9.2 5.6 4.2 7.1 0.9 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Sigma54_AID PF00309.15 ETS76202.1 - 3.7 7.0 15.8 1.6 8.2 3.3 3.1 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) H-kinase_dim PF02895.9 ETS76202.1 - 5.1 7.5 7.3 11 6.4 0.1 2.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain ADIP PF11559.3 ETS76202.1 - 6.2 6.7 14.5 0.34 10.7 2.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ank_5 PF13857.1 ETS76204.1 - 0.003 17.7 0.0 0.11 12.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76204.1 - 0.012 16.1 0.0 1.3 9.6 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS76204.1 - 0.064 13.5 0.0 1.5 9.2 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Zn_clus PF00172.13 ETS76205.1 - 9.9e-06 25.3 11.1 2.3e-05 24.2 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4653 PF15546.1 ETS76205.1 - 1.7 7.8 6.4 2.9 7.1 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) adh_short PF00106.20 ETS76206.1 - 4.7e-23 81.9 0.1 5.9e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS76206.1 - 9.7e-12 45.1 0.1 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS76206.1 - 5.4e-08 32.6 0.1 9.4e-08 31.9 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS76206.1 - 3.3e-05 23.9 0.5 5.9e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS76206.1 - 0.0012 18.3 0.1 0.0025 17.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 ETS76206.1 - 0.0062 15.5 0.2 0.0094 14.9 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 ETS76206.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETS76206.1 - 0.058 13.0 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 ETS76206.1 - 0.083 12.6 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_M3 PF01432.15 ETS76207.1 - 1.3e-99 334.3 2.5 1.8e-99 333.8 1.8 1.1 1 0 0 1 1 1 1 Peptidase family M3 CN_hydrolase PF00795.17 ETS76208.1 - 1.3e-11 44.2 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.5 ETS76209.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit GST_C PF00043.20 ETS76210.1 - 6.5e-10 38.8 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS76210.1 - 2.8e-09 36.9 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS76210.1 - 1.9e-07 30.9 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS76210.1 - 4.8e-07 29.9 0.0 8.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS76210.1 - 5.9e-07 29.9 0.1 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS76210.1 - 2.6e-06 27.2 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NACHT PF05729.7 ETS76211.1 - 1.3e-09 37.9 0.0 3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS76211.1 - 5.8e-07 29.6 0.1 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS76211.1 - 5.8e-06 26.4 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS76211.1 - 0.00034 20.9 0.0 0.00094 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS76211.1 - 0.00089 20.0 0.1 0.0057 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS76211.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETS76211.1 - 0.0076 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS76211.1 - 0.023 14.1 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 ETS76211.1 - 0.059 13.5 0.1 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 ETS76211.1 - 0.11 11.5 0.1 4.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 ETS76211.1 - 0.11 12.2 0.3 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.18 ETS76211.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ytp1 PF10355.4 ETS76212.1 - 1.7e-82 276.6 16.7 1.7e-82 276.6 11.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 ETS76212.1 - 4.9e-32 109.6 1.0 4.9e-32 109.6 0.7 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Glyco_hydro_43 PF04616.9 ETS76213.1 - 1.1e-30 106.7 8.8 1.4e-30 106.4 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FMN_dh PF01070.13 ETS76214.1 - 6.4e-108 360.7 0.0 7.4e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS76214.1 - 3.1e-05 23.0 0.7 4.5e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS76214.1 - 0.00015 20.7 0.2 0.00022 20.2 0.2 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 ETS76214.1 - 0.00035 19.8 0.9 0.00054 19.2 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS76214.1 - 0.0011 18.2 0.2 0.027 13.7 0.1 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 ETS76214.1 - 0.022 13.8 0.6 3.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1212 PF06738.7 ETS76215.1 - 6.3e-53 179.1 14.3 6.5e-50 169.2 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 ETS76215.1 - 1.1e-28 99.7 11.4 1.1e-28 99.7 7.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Peptidase_A8 PF01252.13 ETS76215.1 - 0.0099 15.5 2.9 0.034 13.7 2.0 1.8 1 1 0 1 1 1 1 Signal peptidase (SPase) II DSBA PF01323.15 ETS76216.1 - 9.3e-40 136.2 0.0 1e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETS76216.1 - 2.6e-05 24.2 0.2 3.9e-05 23.7 0.0 1.5 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 ETS76216.1 - 0.00037 20.2 0.1 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_5 PF13743.1 ETS76216.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS76216.1 - 0.022 14.9 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain Glutaredoxin PF00462.19 ETS76216.1 - 0.06 13.3 0.2 0.6 10.1 0.0 2.5 2 1 0 2 2 2 0 Glutaredoxin Acetyltransf_1 PF00583.19 ETS76217.1 - 5.7e-14 51.9 0.2 9.9e-14 51.1 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 ETS76217.1 - 6e-12 45.9 0.0 8.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS76217.1 - 1e-11 45.0 0.1 1.5e-11 44.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS76217.1 - 0.00016 21.5 0.0 0.00038 20.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS76217.1 - 0.0011 19.1 0.1 0.002 18.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS76217.1 - 0.02 14.6 0.2 0.061 13.0 0.0 1.9 2 1 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.1 ETS76217.1 - 0.11 12.5 0.1 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PLU-1 PF08429.6 ETS76219.1 - 6.3e-103 344.1 12.4 1.1e-100 336.7 8.0 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 ETS76219.1 - 4e-41 139.8 0.3 9.8e-41 138.5 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 ETS76219.1 - 1.4e-27 95.3 0.0 3.8e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 ETS76219.1 - 9e-16 57.3 32.8 1.7e-08 34.0 2.7 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 ETS76219.1 - 1.8e-11 43.3 0.3 4e-11 42.2 0.2 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 ETS76219.1 - 6.3e-11 42.1 10.3 6.3e-11 42.1 7.1 2.1 2 0 0 2 2 2 1 C5HC2 zinc finger GIY-YIG PF01541.19 ETS76220.1 - 1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.1 ETS76220.1 - 3.5e-05 23.8 1.1 6.4e-05 23.0 0.8 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 ETS76220.1 - 4.6e-05 23.3 0.8 7.8e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain FANCL_C PF11793.3 ETS76220.1 - 0.006 16.5 2.7 0.011 15.6 1.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 ETS76220.1 - 0.12 12.1 5.5 0.21 11.4 3.8 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 ETS76220.1 - 1.8 8.2 5.5 3.1 7.5 3.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 ETS76220.1 - 7.6 6.6 7.6 28 4.7 5.3 2.0 1 1 0 1 1 1 0 RING-like domain Peptidase_M28 PF04389.12 ETS76221.1 - 5e-26 91.5 0.3 9.7e-26 90.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M28 Ins_allergen_rp PF06757.8 ETS76222.1 - 0.036 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification ELM2 PF01448.19 ETS76222.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 ELM2 domain Abhydrolase_4 PF08386.5 ETS76223.1 - 8e-17 61.0 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS76223.1 - 1.3e-16 60.8 0.1 2e-11 43.9 0.0 2.6 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS76223.1 - 8.9e-06 25.7 0.0 4.9e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_1c PF00749.16 ETS76224.1 - 4.7e-99 331.0 0.0 6.6e-99 330.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 ETS76224.1 - 1.4e-41 142.0 0.1 2.2e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L1 PF00687.16 ETS76225.1 - 1.3e-22 80.2 0.1 1.8e-22 79.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2688 PF10892.3 ETS76225.1 - 0.025 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) HET PF06985.6 ETS76226.1 - 1.1e-25 90.4 0.0 7.7e-25 87.6 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_4 PF08386.5 ETS76227.1 - 8.3e-21 73.8 0.0 3.1e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS76227.1 - 8.9e-14 51.5 0.0 5.7e-12 45.6 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS76227.1 - 1.2e-07 31.8 0.0 1.8e-06 28.0 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76227.1 - 0.0045 16.7 0.0 0.031 14.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 ETS76228.1 - 1.8e-07 30.9 6.3 3.4e-07 30.0 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS76228.1 - 9.5e-07 27.7 0.2 6.4e-06 25.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS76230.1 - 5e-23 81.8 1.5 1.1e-22 80.7 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS76230.1 - 2.3e-14 53.7 0.1 3.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS76230.1 - 1.7e-10 40.8 0.2 2.8e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS76230.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 ETS76230.1 - 0.017 15.2 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Redoxin PF08534.5 ETS76231.1 - 4e-37 127.0 0.0 4.5e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS76231.1 - 4.2e-12 45.8 0.0 5.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF123 PF01986.11 ETS76232.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF123 Fungal_trans PF04082.13 ETS76234.1 - 2.2e-05 23.4 0.2 5.3e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76234.1 - 0.00056 19.7 9.4 0.0013 18.6 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS76235.1 - 3.6e-39 134.4 50.4 2.6e-38 131.6 34.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Lipase_GDSL PF00657.17 ETS76236.1 - 8.2e-09 35.6 0.5 1.1e-08 35.2 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase adh_short PF00106.20 ETS76238.1 - 1.3e-09 38.2 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76238.1 - 4.1e-06 26.5 0.0 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS76238.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Lactonase PF10282.4 ETS76239.1 - 2.7e-59 201.0 0.0 3.5e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller p450 PF00067.17 ETS76240.1 - 1.5e-57 195.1 0.0 2.1e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.1 ETS76241.1 - 1.9e-20 73.4 0.1 3e-20 72.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS76241.1 - 0.011 15.8 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS76241.1 - 0.068 12.9 0.0 0.7 9.6 0.0 2.2 1 1 1 2 2 2 0 FR47-like protein MFS_1 PF07690.11 ETS76244.1 - 4e-33 114.5 43.0 1.9e-30 105.8 19.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76244.1 - 6.7e-12 44.7 17.7 1e-10 40.7 12.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 ETS76244.1 - 0.14 12.5 0.4 0.39 11.1 0.3 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_2 PF00891.13 ETS76245.1 - 2.5e-30 105.4 0.1 3.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase COesterase PF00135.23 ETS76246.1 - 1.9e-89 300.7 0.1 2.7e-89 300.2 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS76246.1 - 1.1e-05 25.1 0.0 5.1e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS76246.1 - 0.073 12.9 0.2 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family CM_2 PF01817.16 ETS76247.1 - 0.014 15.4 0.2 0.014 15.4 0.1 1.9 2 0 0 2 2 2 0 Chorismate mutase type II Helicase_C PF00271.26 ETS76248.1 - 9.4e-12 44.6 0.0 2.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 ETS76248.1 - 4.6e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS76248.1 - 7.1e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Transcript_VP30 PF11507.3 ETS76250.1 - 0.0048 16.7 0.1 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Ebola virus-specific transcription factor VP30 Arf PF00025.16 ETS76251.1 - 5.6e-68 227.5 1.8 6.3e-68 227.4 1.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETS76251.1 - 6.1e-13 48.4 0.0 7.1e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETS76251.1 - 1.1e-12 47.4 1.2 2.9e-07 29.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETS76251.1 - 2.5e-10 39.8 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS76251.1 - 4.8e-10 39.9 0.0 7.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS76251.1 - 2.6e-09 37.0 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS76251.1 - 2.5e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 ETS76251.1 - 3.6e-06 26.5 0.0 0.00031 20.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 ETS76251.1 - 0.0011 19.7 0.1 0.0015 19.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS76251.1 - 0.0034 17.0 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 ETS76251.1 - 0.042 13.3 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 ETS76251.1 - 0.079 12.2 0.3 0.21 10.8 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.13 ETS76251.1 - 0.089 11.8 0.1 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 ETS76252.1 - 5.4e-84 282.8 29.1 1.7e-50 172.5 12.9 6.7 4 3 4 8 8 8 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 ETS76252.1 - 3.6e-09 36.1 0.2 0.00057 19.5 0.0 3.3 3 1 0 3 3 3 2 Gelsolin repeat DUF3894 PF13033.1 ETS76252.1 - 0.85 9.6 0.2 1.6 8.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Ins_allergen_rp PF06757.8 ETS76253.1 - 0.0043 16.5 16.1 8.5 5.8 0.2 5.8 2 2 4 7 7 7 7 Insect allergen related repeat, nitrile-specifier detoxification Acyl-CoA_dh_2 PF08028.6 ETS76254.1 - 8.2e-19 68.1 2.8 1.7e-18 67.1 2.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS76254.1 - 2e-05 25.1 0.1 2e-05 25.1 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 ETS76254.1 - 0.00057 20.0 0.3 0.0012 18.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 ETS76254.1 - 0.017 14.8 0.8 0.21 11.3 0.1 2.9 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2190) Methyltransf_11 PF08241.7 ETS76255.1 - 2.1e-11 44.1 0.0 3.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS76255.1 - 4.4e-11 42.3 0.0 8.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS76255.1 - 3.2e-08 33.8 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76255.1 - 2.1e-06 27.5 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76255.1 - 4.7e-05 23.7 0.0 8.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 ETS76255.1 - 6.6e-05 22.0 0.0 9.8e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 ETS76255.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETS76255.1 - 0.094 12.7 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain S1-P1_nuclease PF02265.11 ETS76256.1 - 2.9e-71 240.0 0.0 3.3e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PDEase_II PF02112.10 ETS76257.1 - 3.6e-55 187.2 0.0 1.9e-22 79.6 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 ETS76257.1 - 0.00036 20.1 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1326 PF07040.6 ETS76257.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) AMP-binding PF00501.23 ETS76259.1 - 4.4e-59 199.9 0.2 8.7e-31 106.7 0.0 4.7 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 ETS76259.1 - 1.8e-11 44.5 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 ETS76259.1 - 8e-05 22.3 0.4 0.00019 21.1 0.3 1.6 1 0 0 1 1 1 1 Gas vesicle protein G SHOCT PF09851.4 ETS76259.1 - 0.45 10.0 2.7 0.85 9.1 1.9 1.5 1 0 0 1 1 1 0 Short C-terminal domain Zn_clus PF00172.13 ETS76260.1 - 4.2e-09 36.1 6.3 7e-09 35.4 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 ETS76261.1 - 6.5e-59 199.5 0.0 1.2e-58 198.6 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS76261.1 - 2.9e-19 69.9 0.0 4.8e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS76261.1 - 4e-09 36.3 0.0 9.5e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS76261.1 - 4.4e-07 29.9 0.0 5.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS76261.1 - 1.1e-06 28.5 1.1 7.3e-05 22.5 0.1 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS76261.1 - 3.8e-06 26.0 0.6 1.3e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS76261.1 - 1.1e-05 24.4 0.5 0.00013 20.9 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 ETS76261.1 - 0.00052 20.0 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding Pyr_redox PF00070.22 ETS76261.1 - 0.001 19.3 0.0 0.074 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS76261.1 - 0.0035 15.8 0.1 0.0055 15.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS76261.1 - 0.031 13.3 0.0 0.16 11.0 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.19 ETS76261.1 - 0.04 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS76261.1 - 0.086 11.9 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 ETS76261.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 ETS76261.1 - 0.13 11.1 0.0 0.97 8.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain ABC_tran PF00005.22 ETS76262.1 - 2e-51 173.8 0.0 2.4e-30 105.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS76262.1 - 5.5e-48 163.7 18.8 3.1e-26 92.3 3.0 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 ETS76262.1 - 1.3e-08 35.1 0.1 0.051 13.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETS76262.1 - 2.1e-08 34.7 0.0 0.00012 22.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 ETS76262.1 - 9.5e-08 31.5 0.6 0.1 11.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 ETS76262.1 - 6.6e-06 25.7 0.0 0.033 13.6 0.0 3.1 2 1 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 ETS76262.1 - 1.5e-05 24.4 0.0 0.075 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS76262.1 - 3.6e-05 23.2 0.2 0.29 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 ETS76262.1 - 7.6e-05 21.7 0.1 0.036 12.9 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 ETS76262.1 - 8.9e-05 21.7 0.0 0.22 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETS76262.1 - 0.00017 20.7 0.8 0.13 11.3 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 ETS76262.1 - 0.00017 21.3 0.6 0.28 10.8 0.0 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ETS76262.1 - 0.00018 21.4 0.1 0.11 12.4 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 ETS76262.1 - 0.00018 22.2 0.0 1.5 9.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS76262.1 - 0.0002 21.4 0.2 6.3 6.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 ETS76262.1 - 0.00041 20.2 0.3 0.023 14.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 ETS76262.1 - 0.00084 19.8 0.4 2.1 8.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 ETS76262.1 - 0.0012 19.1 0.6 3 8.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 ETS76262.1 - 0.0016 18.5 2.9 0.82 9.6 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 ETS76262.1 - 0.0038 16.9 0.1 0.3 10.7 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 ETS76262.1 - 0.0095 15.3 0.0 3.1 7.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 ETS76262.1 - 0.012 15.1 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 ETS76262.1 - 0.014 15.6 0.1 8.9 6.5 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 ETS76262.1 - 0.017 14.7 0.2 5 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETS76262.1 - 0.033 14.0 0.8 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 ETS76262.1 - 0.039 13.8 0.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 ETS76262.1 - 0.051 12.9 1.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1180 PF06679.7 ETS76262.1 - 0.063 13.1 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNA_helicase PF00910.17 ETS76262.1 - 0.1 12.8 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 ETS76262.1 - 0.17 11.3 2.3 1 8.7 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 ETS76262.1 - 0.21 11.2 2.5 4 7.0 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 ETS76262.1 - 0.28 10.4 0.5 10 5.3 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.1 ETS76262.1 - 0.4 10.4 3.7 2.8 7.7 0.0 3.4 3 0 0 3 3 2 0 Part of AAA domain RTA1 PF04479.8 ETS76263.1 - 1.7e-34 119.3 4.6 2.4e-34 118.8 3.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Dioxygenase_C PF00775.16 ETS76264.1 - 7.6e-11 41.5 0.3 2e-08 33.7 0.0 2.7 2 1 0 2 2 2 2 Dioxygenase SIR2 PF02146.12 ETS76265.1 - 2.1e-39 135.0 0.0 3.7e-39 134.2 0.0 1.4 1 1 0 1 1 1 1 Sir2 family TPR_12 PF13424.1 ETS76266.1 - 8.8e-68 224.2 23.9 2.5e-18 65.7 0.6 6.1 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETS76266.1 - 8e-60 197.2 4.6 1e-09 38.0 0.0 8.8 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76266.1 - 1.4e-36 122.5 35.1 1.4e-05 24.4 1.1 8.8 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 ETS76266.1 - 4.2e-34 113.6 14.5 0.00022 20.8 0.1 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 ETS76266.1 - 1.5e-26 90.1 26.4 0.0014 18.4 0.2 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 ETS76266.1 - 3.3e-25 87.4 23.1 2.4e-08 33.4 1.6 5.8 2 2 6 8 8 8 7 TPR repeat HET PF06985.6 ETS76266.1 - 5.6e-23 81.6 6.1 3.6e-21 75.7 2.9 3.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_17 PF13431.1 ETS76266.1 - 2.4e-16 58.4 11.0 0.95 9.8 0.1 9.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76266.1 - 6.2e-16 56.9 36.3 0.002 17.7 0.8 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS76266.1 - 6.9e-14 52.0 17.3 0.00076 20.0 0.2 6.4 5 2 1 6 6 5 4 Tetratricopeptide repeat NB-ARC PF00931.17 ETS76266.1 - 1.1e-13 50.6 0.0 1.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 ETS76266.1 - 1e-11 44.3 15.3 0.6 10.9 0.1 8.6 7 2 2 9 9 7 3 Tetratricopeptide repeat AAA_16 PF13191.1 ETS76266.1 - 1.1e-08 35.2 0.1 3.5e-08 33.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain PPR PF01535.15 ETS76266.1 - 2.3e-08 33.4 8.1 4 7.6 0.0 7.3 7 0 0 7 7 7 2 PPR repeat RPN7 PF10602.4 ETS76266.1 - 0.00033 20.1 12.0 5.5 6.3 0.0 6.6 5 2 2 8 8 7 1 26S proteasome subunit RPN7 Arch_ATPase PF01637.13 ETS76266.1 - 0.0013 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase SPO22 PF08631.5 ETS76266.1 - 0.0031 16.6 4.0 1.3 8.0 0.1 4.0 2 2 1 4 4 4 1 Meiosis protein SPO22/ZIP4 like AAA_22 PF13401.1 ETS76266.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_3 PF07720.7 ETS76266.1 - 0.0069 16.1 23.0 0.98 9.2 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS76266.1 - 0.0073 16.6 0.0 39 5.0 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_14 PF13173.1 ETS76266.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2225 PF09986.4 ETS76266.1 - 1 8.8 12.3 2.8 7.3 1.1 3.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 ETS76266.1 - 1 9.9 37.2 0.46 11.0 0.9 8.3 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETS76266.1 - 2.5 8.0 11.1 70 3.3 0.2 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS76266.1 - 6.3 7.2 27.6 14 6.1 0.3 6.2 2 1 6 8 8 7 0 Tetratricopeptide repeat DLH PF01738.13 ETS76267.1 - 4.3e-13 49.0 0.1 5.1e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.13 ETS76268.1 - 2.5e-13 49.5 0.6 5.3e-13 48.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76268.1 - 1.3e-08 34.6 17.7 2.3e-08 33.7 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC4_C PF14629.1 ETS76268.1 - 0.13 11.6 1.6 0.2 11.0 0.1 1.9 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF1345 PF07077.6 ETS76270.1 - 0.0093 15.4 2.5 0.015 14.8 1.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1345) YfhO PF09586.5 ETS76270.1 - 0.79 7.6 4.4 0.96 7.3 3.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2069 PF09842.4 ETS76270.1 - 0.81 9.6 9.1 0.54 10.2 0.1 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2069) DUF1772 PF08592.6 ETS76270.1 - 4 7.1 10.0 0.79 9.4 2.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) Prion_bPrPp PF11587.3 ETS76270.1 - 5.3 6.8 7.3 10 5.9 2.4 2.7 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal PNTB PF02233.11 ETS76271.1 - 6e-170 565.9 24.3 6e-170 565.9 16.9 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 ETS76271.1 - 1.8e-53 180.5 1.0 3.1e-53 179.7 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 ETS76271.1 - 2.6e-49 166.7 0.0 8e-49 165.1 0.0 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 ETS76271.1 - 1.3e-31 108.6 3.7 1.3e-31 108.6 2.6 5.6 4 2 2 6 6 6 1 Domain of unknown function (DUF3814) TPP_enzyme_M PF00205.17 ETS76271.1 - 0.00083 19.1 0.6 0.01 15.6 0.2 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.14 ETS76271.1 - 0.0023 17.1 0.1 0.33 10.1 0.0 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 ETS76271.1 - 0.0065 16.0 0.1 0.025 14.1 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fumerase PF05681.9 ETS76271.1 - 0.0079 15.3 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Methyltransf_31 PF13847.1 ETS76271.1 - 0.024 14.2 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 ETS76271.1 - 0.031 14.1 1.3 0.11 12.3 0.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS76271.1 - 0.077 11.8 1.1 0.13 11.0 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS76271.1 - 0.083 12.9 7.7 1.6 8.8 0.0 4.6 5 1 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase Tyrosinase PF00264.15 ETS76272.1 - 3.3e-36 125.5 3.7 5.7e-36 124.7 2.5 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Zn_clus PF00172.13 ETS76273.1 - 2.3e-06 27.3 13.2 2.3e-06 27.3 9.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS76274.1 - 3.2e-45 154.3 24.8 3.2e-45 154.3 17.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76274.1 - 3.2e-11 42.4 16.0 1.7e-10 40.1 11.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter SET PF00856.23 ETS76275.1 - 3.7e-15 56.5 0.0 1.7e-14 54.4 0.0 2.1 2 1 0 2 2 2 1 SET domain SAF PF08666.7 ETS76275.1 - 0.0052 17.1 0.2 5.5 7.4 0.0 2.4 2 0 0 2 2 2 2 SAF domain Vfa1 PF08432.5 ETS76276.1 - 0.078 12.9 1.9 0.1 12.5 1.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cellulase PF00150.13 ETS76277.1 - 2e-54 184.7 0.2 2.6e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PLDc_2 PF13091.1 ETS76278.1 - 3.3e-14 52.7 0.0 4.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETS76278.1 - 7.9e-08 31.8 1.5 0.021 14.6 0.2 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 ETS76279.1 - 1.4e-26 93.0 1.1 1.8e-26 92.6 0.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TMEMspv1-c74-12 PF11044.3 ETS76280.1 - 0.16 11.5 0.8 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Abhydrolase_6 PF12697.2 ETS76281.1 - 2e-25 90.0 0.1 2.3e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76281.1 - 3.3e-12 46.3 0.0 5.2e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS76281.1 - 5e-05 23.0 0.0 0.00093 18.8 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 ETS76281.1 - 0.00012 21.5 0.0 0.0011 18.3 0.0 2.3 3 0 0 3 3 3 1 Putative serine esterase (DUF676) DUF900 PF05990.7 ETS76281.1 - 0.0088 15.3 0.0 0.028 13.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 ETS76281.1 - 0.049 13.1 0.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 ETS76281.1 - 0.063 12.7 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF218 PF02698.12 ETS76282.1 - 3.2e-27 94.9 0.0 4.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain AMP-binding PF00501.23 ETS76283.1 - 2.9e-75 253.2 0.0 3.7e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS76283.1 - 2.8e-12 47.3 0.1 1.5e-11 45.0 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ank PF00023.25 ETS76284.1 - 2.5e-08 33.3 0.8 5.6e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 ETS76284.1 - 5e-08 33.1 0.1 2.6e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS76284.1 - 3e-06 27.2 0.2 1.4e-05 25.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76284.1 - 0.00026 21.3 0.0 0.0007 20.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76284.1 - 0.0068 16.5 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat OTT_1508_deam PF14441.1 ETS76284.1 - 0.0076 16.0 0.3 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase MFS_1 PF07690.11 ETS76285.1 - 1.2e-34 119.5 28.1 1.2e-34 119.5 19.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily GlpM PF06942.7 ETS76285.1 - 0.013 15.7 1.7 0.013 15.7 1.2 3.0 4 0 0 4 4 4 0 GlpM protein p450 PF00067.17 ETS76286.1 - 2.4e-64 217.5 0.0 3e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.14 ETS76287.1 - 1.8e-12 47.4 13.8 2.3e-12 47.0 8.6 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS76287.1 - 1.6e-07 31.1 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS76287.1 - 3.1e-07 30.4 0.0 6.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Glyco_hydro_28 PF00295.12 ETS76288.1 - 3.8e-28 98.3 5.4 3.8e-28 98.3 3.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Baculo_PEP_C PF04513.7 ETS76289.1 - 0.0054 16.5 4.5 0.0054 16.5 3.1 5.3 3 2 2 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus NACHT PF05729.7 ETS76293.1 - 3.1e-10 39.9 0.2 3.7e-08 33.2 0.1 2.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS76293.1 - 4.9e-06 26.7 0.0 2.6e-05 24.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS76293.1 - 2.4e-05 24.6 1.8 0.0017 18.6 0.0 3.5 3 1 0 3 3 3 1 ABC transporter Arch_ATPase PF01637.13 ETS76293.1 - 0.0024 17.6 0.0 0.015 14.9 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_30 PF13604.1 ETS76293.1 - 0.0043 16.6 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS76293.1 - 0.0053 16.7 8.5 0.0058 16.6 0.0 4.3 4 2 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 ETS76293.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS76293.1 - 0.021 15.6 0.3 0.15 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS76293.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 ETS76293.1 - 0.059 13.6 0.4 0.27 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Av_adeno_fibre PF06536.6 ETS76293.1 - 0.077 12.7 0.9 0.22 11.2 0.2 2.0 2 0 0 2 2 2 0 Avian adenovirus fibre AAA_23 PF13476.1 ETS76293.1 - 0.13 12.6 0.8 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain FAD_oxidored PF12831.2 ETS76295.1 - 1.1e-88 298.2 0.0 1.5e-88 297.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 ETS76295.1 - 1.3e-29 102.9 0.3 2.1e-29 102.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trp_halogenase PF04820.9 ETS76295.1 - 0.008 14.8 0.9 0.21 10.1 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS76295.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS76295.1 - 0.044 12.6 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 ETS76295.1 - 0.11 11.5 0.2 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 ETS76295.1 - 0.37 9.5 2.8 1.5 7.6 0.4 2.5 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.2 ETS76296.1 - 1.6e-88 297.6 0.0 1.8e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS76296.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Sugar_tr PF00083.19 ETS76297.1 - 3.2e-90 302.8 13.5 4.3e-90 302.4 9.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76297.1 - 5.6e-21 74.6 25.0 3.2e-16 58.9 4.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS76297.1 - 0.00022 19.7 0.4 0.00022 19.7 0.3 4.2 4 1 1 5 5 5 2 MFS/sugar transport protein BT1 PF03092.11 ETS76297.1 - 0.00062 18.5 1.9 0.0063 15.2 1.2 2.1 1 1 0 1 1 1 1 BT1 family GCV_T_C PF08669.6 ETS76297.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain EBP PF05241.7 ETS76297.1 - 0.031 13.3 2.0 0.056 12.4 0.6 2.0 2 0 0 2 2 2 0 Emopamil binding protein DUF2275 PF10039.4 ETS76297.1 - 0.14 12.0 0.1 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) adh_short_C2 PF13561.1 ETS76299.1 - 3.4e-27 95.7 0.1 3.9e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS76299.1 - 1.5e-26 93.3 2.9 2.3e-26 92.7 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76299.1 - 7.6e-13 48.5 0.7 1.4e-12 47.6 0.5 1.4 1 1 0 1 1 1 1 KR domain ThiF PF00899.16 ETS76299.1 - 0.0067 16.2 5.1 0.4 10.4 1.3 2.4 1 1 1 2 2 2 2 ThiF family Polysacc_synt_2 PF02719.10 ETS76299.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-C2H2 PF00096.21 ETS76300.1 - 1.5e-05 25.0 22.5 0.00013 22.0 3.9 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS76300.1 - 3.3e-05 23.9 17.1 0.0017 18.5 3.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS76300.1 - 0.00015 21.8 19.2 0.001 19.2 3.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-UBR PF02207.15 ETS76300.1 - 0.0014 18.2 2.9 0.0024 17.5 2.0 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-C2H2_jaz PF12171.3 ETS76300.1 - 0.024 14.7 2.4 0.024 14.7 1.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 ETS76300.1 - 0.048 13.3 1.0 0.048 13.3 0.7 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF2225 PF09986.4 ETS76300.1 - 0.11 11.9 1.6 0.2 11.0 1.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_2 PF12756.2 ETS76300.1 - 6.4 6.9 9.8 8.4 6.5 2.5 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) NmrA PF05368.8 ETS76301.1 - 9.9e-19 67.5 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 ETS76301.1 - 0.00023 20.2 0.0 0.00029 19.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 ETS76301.1 - 0.00058 19.9 0.0 0.091 12.8 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 ETS76301.1 - 0.04 14.3 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Fork_head PF00250.13 ETS76302.1 - 1.5e-27 95.4 0.6 2.9e-27 94.5 0.4 1.4 1 0 0 1 1 1 1 Fork head domain MIF4G PF02854.14 ETS76303.1 - 5e-29 101.2 0.5 1e-28 100.1 0.3 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 ETS76303.1 - 6.1e-21 74.2 1.8 1.1e-20 73.3 0.1 2.3 3 0 0 3 3 3 1 MA3 domain Vert_IL3-reg_TF PF06529.6 ETS76303.1 - 0.3 9.9 2.2 0.51 9.2 1.5 1.2 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor NOA36 PF06524.7 ETS76303.1 - 2.8 7.1 6.6 4.5 6.4 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein DPM2 PF07297.7 ETS76304.1 - 3.2e-30 104.2 3.0 3.7e-30 104.0 2.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 ETS76304.1 - 0.00023 20.7 1.8 0.00025 20.6 1.2 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 ETS76304.1 - 0.00024 20.9 1.0 0.00024 20.9 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 ETS76304.1 - 0.0086 15.8 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) Herpes_UL43 PF05072.8 ETS76304.1 - 0.036 12.8 0.3 0.052 12.3 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL43 protein COX14 PF14880.1 ETS76304.1 - 0.038 13.6 0.7 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DiS_P_DiS PF06750.8 ETS76304.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF1049 PF06305.6 ETS76304.1 - 1.7 8.2 4.2 0.45 10.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PP2C PF00481.16 ETS76306.1 - 4.4e-31 108.1 0.0 6.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3262 PF11660.3 ETS76306.1 - 0.14 12.2 0.3 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) SpoIIE PF07228.7 ETS76306.1 - 0.16 11.6 0.0 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) BAF1_ABF1 PF04684.8 ETS76307.1 - 1.7 7.4 8.5 2.3 6.9 5.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PUF PF00806.14 ETS76308.1 - 5.1e-50 164.2 7.3 9.4e-09 34.2 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fungal_trans PF04082.13 ETS76310.1 - 7.9e-11 41.3 0.8 1.3e-10 40.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76310.1 - 1e-08 34.9 10.4 1.9e-08 34.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 ETS76310.1 - 2.8 7.7 11.7 9.9 5.9 8.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Phosphodiest PF01663.17 ETS76311.1 - 9.3e-13 48.2 0.3 1.8e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS76311.1 - 6.9e-05 22.1 0.1 0.00013 21.2 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 ETS76311.1 - 0.00012 21.6 0.9 0.0002 20.8 0.6 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DLIC PF05783.6 ETS76312.1 - 0.027 13.1 2.2 0.049 12.3 1.3 1.4 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) Sporozoite_P67 PF05642.6 ETS76312.1 - 0.45 8.3 8.2 0.68 7.7 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 ETS76312.1 - 3 7.0 12.3 5.3 6.2 8.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ABC_membrane PF00664.18 ETS76313.1 - 1.9e-88 296.4 42.2 1.4e-45 155.8 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS76313.1 - 1.2e-66 223.2 0.0 1.4e-32 112.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS76313.1 - 6.9e-12 45.0 0.0 0.00025 20.3 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS76313.1 - 3.1e-10 40.4 1.3 0.016 15.2 0.2 4.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS76313.1 - 2.3e-08 33.4 5.1 0.00031 20.1 0.1 4.0 4 0 0 4 4 4 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 ETS76313.1 - 3.2e-08 32.5 4.0 0.0059 15.2 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 ETS76313.1 - 2.3e-07 31.6 0.1 0.057 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS76313.1 - 4.1e-06 26.0 0.0 0.14 11.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS76313.1 - 8.4e-06 25.8 6.9 0.0037 17.2 0.0 3.8 4 1 0 4 4 4 2 AAA ATPase domain AAA_25 PF13481.1 ETS76313.1 - 1.9e-05 24.1 0.3 0.33 10.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 ETS76313.1 - 0.00045 20.3 1.4 2.8 8.0 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS76313.1 - 0.0027 17.9 0.1 3.1 8.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS76313.1 - 0.0039 17.1 0.6 0.66 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS76313.1 - 0.0065 16.3 0.0 2 8.2 0.0 3.6 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 ETS76313.1 - 0.0066 16.3 5.5 1.1 9.1 0.1 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 ETS76313.1 - 0.0079 16.5 0.3 0.71 10.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 ETS76313.1 - 0.0088 15.6 4.4 4 6.9 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 ETS76313.1 - 0.016 14.9 1.1 9.5 5.9 0.0 3.3 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETS76313.1 - 0.019 14.8 2.4 5.7 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain PapJ PF14855.1 ETS76313.1 - 0.023 14.1 0.3 0.59 9.5 0.0 2.4 2 0 0 2 2 2 0 Pilus-assembly fibrillin subunit, chaperone DUF87 PF01935.12 ETS76313.1 - 0.034 13.9 4.1 5.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 ETS76313.1 - 0.049 13.3 1.1 15 5.2 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 ETS76313.1 - 0.071 12.5 2.9 12 5.1 0.2 3.6 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 ETS76313.1 - 0.08 13.1 0.7 15 5.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase G-alpha PF00503.15 ETS76313.1 - 0.082 11.5 0.0 7.8 5.0 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 ETS76313.1 - 0.32 10.9 1.4 11 5.9 0.1 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase LMBR1 PF04791.11 ETS76314.1 - 2.6e-29 102.1 2.1 4.5e-29 101.3 1.5 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Poty_coat PF00767.13 ETS76314.1 - 0.16 11.2 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Potyvirus coat protein UPF0113 PF03657.8 ETS76315.1 - 9.5e-07 28.6 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 ETS76315.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 ETS76316.1 - 6.1e-29 100.1 3.3 6.9e-29 99.9 0.1 2.7 2 1 1 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 ETS76316.1 - 8e-27 93.6 0.0 2.5e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 CBF/Mak21 family DUF3860 PF12976.2 ETS76317.1 - 0.013 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) DUF1908 PF08926.6 ETS76317.1 - 0.48 9.1 3.6 0.44 9.2 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1908) RNase_P_pop3 PF08228.6 ETS76318.1 - 1.2e-11 44.6 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 UCH PF00443.24 ETS76319.1 - 2.6e-45 154.6 0.4 3.7e-44 150.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS76319.1 - 5.1e-17 62.2 1.2 1.5e-16 60.7 0.3 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 ETS76319.1 - 2.3e-12 46.1 0.0 5.6e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) DUF4175 PF13779.1 ETS76320.1 - 0.43 8.2 12.5 0.62 7.7 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FimP PF09766.4 ETS76320.1 - 0.61 9.1 5.7 0.9 8.5 4.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein APC_CDC26 PF10471.4 ETS76320.1 - 2.3 8.9 13.8 3.9 8.2 7.6 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Apc15p PF05841.6 ETS76320.1 - 2.4 8.9 10.9 0.28 11.9 1.0 2.7 2 0 0 2 2 2 0 Apc15p protein DNA_pol3_alpha PF07733.7 ETS76323.1 - 0.013 13.9 0.2 0.014 13.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit Mod_r PF07200.8 ETS76323.1 - 0.021 14.7 1.8 0.085 12.7 0.5 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NACHT PF05729.7 ETS76324.1 - 6.4e-05 22.6 0.1 0.00042 20.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS76324.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS76324.1 - 0.01 15.7 0.0 0.059 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain PD40 PF07676.7 ETS76324.1 - 0.019 14.6 0.2 15 5.4 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 ETS76324.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PQQ PF01011.16 ETS76324.1 - 0.099 12.2 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat AAA PF00004.24 ETS76324.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Reo_sigmaC PF04582.7 ETS76325.1 - 0.0025 17.0 6.6 0.014 14.6 0.2 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 ETS76325.1 - 0.0069 15.9 2.1 0.017 14.7 0.1 2.1 2 0 0 2 2 2 1 IncA protein KxDL PF10241.4 ETS76325.1 - 0.012 15.5 0.1 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Myosin_tail_1 PF01576.14 ETS76325.1 - 0.081 10.6 0.1 0.12 10.0 0.1 1.3 1 1 0 1 1 1 0 Myosin tail DUF3176 PF11374.3 ETS76326.1 - 1.9e-26 92.1 2.2 1.9e-26 92.1 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) TPP_enzyme_N PF02776.13 ETS76326.1 - 5.9e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2534 PF10749.4 ETS76326.1 - 8.9 6.3 7.2 0.3 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) HET PF06985.6 ETS76327.1 - 6.3e-22 78.2 0.0 1.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tyrosinase PF00264.15 ETS76328.1 - 5.7e-27 95.3 1.9 7.8e-27 94.8 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.14 ETS76329.1 - 7.5e-10 38.3 1.9 7.7e-05 21.9 0.0 3.0 3 1 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 ETS76329.1 - 9.7e-08 30.8 0.0 1.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 ETS76329.1 - 8e-06 24.9 0.0 0.0042 16.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS76329.1 - 5.9e-05 23.0 0.0 0.00024 21.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS76329.1 - 0.0003 19.7 0.0 0.00047 19.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS76329.1 - 0.0059 16.5 0.0 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76329.1 - 0.019 15.3 0.1 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS76329.1 - 0.037 13.1 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 ETS76329.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.18 ETS76330.1 - 2.1e-21 75.8 0.9 4e-21 74.9 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Clr5 PF14420.1 ETS76332.1 - 1.8e-15 56.5 5.0 4.6e-15 55.2 3.5 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.2 ETS76333.1 - 4.4e-33 113.4 7.4 4.2e-16 59.0 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76333.1 - 4.8e-20 70.2 7.5 4.8e-05 22.9 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS76333.1 - 5.4e-18 65.0 0.2 1.5e-05 25.3 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76333.1 - 2.2e-16 59.4 2.5 2.8e-06 27.3 0.0 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 ETS76333.1 - 1.2e-13 50.5 1.4 9.6e-13 47.6 1.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_3 PF13606.1 ETS76333.1 - 3.4e-11 42.2 0.2 0.00084 19.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.7 ETS76333.1 - 1.1e-05 25.2 0.0 3.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS76333.1 - 1.1e-05 25.5 0.3 0.011 15.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS76333.1 - 8.7e-05 22.5 1.1 0.00044 20.2 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AFG1_ATPase PF03969.11 ETS76333.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase KAP_NTPase PF07693.9 ETS76333.1 - 0.08 11.9 0.1 2.2 7.1 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain SPC12 PF06645.8 ETS76334.1 - 0.13 12.0 0.3 0.59 9.9 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2976 PF11190.3 ETS76334.1 - 8.4 5.9 7.9 2 8.0 1.4 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) GST_N_3 PF13417.1 ETS76336.1 - 1.1e-08 35.2 0.1 4.9e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS76336.1 - 0.0014 18.5 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Caps_synth_GfcC PF06251.6 ETS76336.1 - 0.065 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC MFS_1 PF07690.11 ETS76337.1 - 1.6e-33 115.9 41.6 1.6e-33 115.9 28.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76337.1 - 3.1e-13 49.1 11.6 3.1e-13 49.1 8.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter NADH-u_ox-rdase PF10785.4 ETS76337.1 - 0.046 13.9 8.9 0.23 11.7 0.0 3.9 4 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit p450 PF00067.17 ETS76338.1 - 3.4e-70 236.8 0.0 4.4e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS76339.1 - 8.4e-50 169.6 0.0 1.1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 ETS76340.1 - 1.2e-11 44.5 25.6 1.2e-11 44.5 17.7 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Clr5 PF14420.1 ETS76341.1 - 2.4e-15 56.1 1.2 4.8e-15 55.1 0.8 1.5 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.2 ETS76342.1 - 2.1e-33 114.5 7.7 8.7e-16 58.0 0.3 5.4 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76342.1 - 6.1e-25 85.7 6.7 0.0045 16.7 0.0 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 ETS76342.1 - 7.4e-24 81.4 3.8 0.0012 18.8 0.0 8.2 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETS76342.1 - 1.2e-21 76.6 7.5 8.3e-05 22.9 0.0 6.9 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76342.1 - 1e-19 70.0 7.0 0.0078 16.4 0.0 7.3 3 3 3 6 6 6 6 Ankyrin repeats (many copies) PLAC9 PF15205.1 ETS76342.1 - 0.0023 18.1 0.1 0.069 13.4 0.0 2.7 2 0 0 2 2 2 1 Placenta-specific protein 9 LIM PF00412.17 ETS76344.1 - 1.2e-08 34.8 13.0 8.4e-08 32.1 4.3 2.6 1 1 1 2 2 2 2 LIM domain DUF4317 PF14199.1 ETS76344.1 - 0.012 14.4 1.2 0.017 13.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Syntaxin PF00804.20 ETS76344.1 - 0.013 15.6 2.6 0.029 14.5 1.8 1.6 1 0 0 1 1 1 0 Syntaxin bZIP_1 PF00170.16 ETS76344.1 - 0.12 12.3 0.2 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor PRCC PF10253.4 ETS76345.1 - 2.9e-36 125.8 1.0 2.9e-36 125.8 0.7 3.0 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 ETS76346.1 - 1.2e-35 123.0 6.1 2.8e-18 65.7 0.0 3.8 3 1 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 ETS76346.1 - 0.0041 16.9 0.1 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Cytomega_UL20A PF05984.7 ETS76347.1 - 0.14 12.3 2.4 0.19 11.9 1.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Myco_19_kDa PF05481.7 ETS76347.1 - 0.66 9.7 11.5 0.71 9.6 7.9 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SOG2 PF10428.4 ETS76348.1 - 10 4.6 15.1 15 4.0 10.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cas_csx3 PF09620.5 ETS76349.1 - 0.033 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cu_bind_like PF02298.12 ETS76349.1 - 0.07 12.9 0.2 0.25 11.1 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain DUF3129 PF11327.3 ETS76350.1 - 2.1e-29 102.6 10.8 2.1e-29 102.6 7.5 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF3129) Amidohydro_2 PF04909.9 ETS76351.1 - 9.8e-41 140.1 0.2 1.3e-40 139.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 ETS76351.1 - 0.031 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Asparaginase DUF3176 PF11374.3 ETS76352.1 - 1.2e-30 105.6 0.1 2.8e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Pam17 PF08566.5 ETS76352.1 - 0.021 14.4 0.2 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF3433 PF11915.3 ETS76352.1 - 0.041 14.0 1.3 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) Gag_p24 PF00607.15 ETS76353.1 - 0.25 10.8 4.8 0.17 11.3 0.7 2.1 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) TMF_TATA_bd PF12325.3 ETS76353.1 - 0.33 10.7 5.2 1.1 9.0 2.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Peroxin-13_N PF04088.8 ETS76353.1 - 0.99 9.3 4.4 0.47 10.3 0.7 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region WD40 PF00400.27 ETS76354.1 - 8.2e-20 69.8 21.7 7.8e-08 31.9 0.0 12.0 13 0 0 13 13 13 4 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS76354.1 - 3.2e-11 43.1 1.3 0.019 14.4 0.0 4.8 3 1 0 3 3 3 3 PQQ-like domain NACHT PF05729.7 ETS76354.1 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETS76354.1 - 0.0002 20.9 4.1 2.6 7.7 0.2 6.6 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETS76354.1 - 0.00067 19.4 0.1 5.4 6.6 0.0 4.4 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 ETS76354.1 - 0.00077 19.4 0.9 0.01 15.8 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS76354.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Proteasome_A_N PF10584.4 ETS76354.1 - 0.027 13.8 5.9 13 5.1 0.0 6.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature AAA_22 PF13401.1 ETS76354.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS76354.1 - 0.083 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 ETS76354.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 ETS76354.1 - 0.19 10.6 0.1 13 4.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 ETS76354.1 - 0.22 10.4 0.1 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nucleoporin_N PF08801.6 ETS76354.1 - 0.89 8.2 7.4 1.3 7.6 0.0 3.6 2 1 0 3 3 3 0 Nup133 N terminal like p450 PF00067.17 ETS76355.1 - 2.2e-44 151.7 0.0 3.2e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 ETS76356.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS76356.1 - 3.7e-17 62.4 0.0 5.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CheW PF01584.14 ETS76356.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 CheW-like domain Abhydrolase_6 PF12697.2 ETS76357.1 - 7.4e-06 26.0 0.3 1.2e-05 25.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76357.1 - 3.1e-05 23.7 2.0 8.1e-05 22.4 1.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS76357.1 - 0.0013 18.3 0.5 0.0041 16.7 0.0 2.0 3 0 0 3 3 3 1 PGAP1-like protein DUF676 PF05057.9 ETS76357.1 - 0.002 17.4 0.0 0.0035 16.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 ETS76357.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 ETS76357.1 - 0.09 12.2 0.2 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PTPLA PF04387.9 ETS76358.1 - 5.6e-45 152.7 4.3 8.4e-45 152.1 3.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA HET PF06985.6 ETS76359.1 - 2.8e-30 105.2 0.1 1.2e-29 103.1 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ebola_NP PF05505.7 ETS76360.1 - 0.063 11.3 0.0 0.087 10.8 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein HEAT PF02985.17 ETS76362.1 - 0.00043 20.1 0.0 0.024 14.6 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 ETS76362.1 - 0.00096 19.3 0.0 0.025 14.8 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats Cohesin_HEAT PF12765.2 ETS76362.1 - 0.0098 15.8 0.5 0.029 14.3 0.4 1.7 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion zf-C2H2_4 PF13894.1 ETS76362.1 - 0.083 13.2 18.5 0.52 10.7 0.1 5.8 4 1 0 4 4 4 0 C2H2-type zinc finger Attractin PF08037.6 ETS76362.1 - 0.091 12.5 1.7 0.25 11.1 1.1 1.8 1 0 0 1 1 1 0 Attractin family zf-Di19 PF05605.7 ETS76362.1 - 1 9.5 13.6 20 5.3 0.6 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 ETS76362.1 - 2.9 8.0 8.1 0.16 12.0 0.2 2.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Peptidase_S8 PF00082.17 ETS76363.1 - 1.1e-16 60.7 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_88 PF07470.8 ETS76365.1 - 7e-63 212.6 12.1 9.3e-63 212.2 8.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF3328 PF11807.3 ETS76366.1 - 1.5e-28 99.9 0.0 2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Bac_luciferase PF00296.15 ETS76367.1 - 5.2e-64 216.2 0.0 6.4e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 ETS76368.1 - 5.5e-45 153.6 44.8 5.5e-45 153.6 31.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76368.1 - 3.8e-17 62.0 26.0 6.1e-15 54.7 9.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Pox_A14 PF05767.7 ETS76368.1 - 0.079 12.9 0.2 0.33 10.9 0.2 2.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 AMP-binding PF00501.23 ETS76369.1 - 2.2e-79 266.8 0.0 3.2e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS76369.1 - 1.8e-66 223.6 0.1 2.6e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS76369.1 - 8.9e-13 48.2 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS76369.1 - 1.2e-10 41.5 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS76369.1 - 1.3e-08 35.6 0.0 6e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 ETS76369.1 - 1.7e-08 33.4 0.0 4.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS76369.1 - 0.015 15.2 0.4 0.087 12.7 0.3 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS76369.1 - 0.016 14.0 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETS76369.1 - 0.044 12.6 0.1 0.58 9.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Arylsulfotran_2 PF14269.1 ETS76370.1 - 1.3e-75 254.3 0.9 1.6e-75 254.0 0.3 1.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS76370.1 - 3.8e-14 52.0 0.1 4e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MIP PF00230.15 ETS76371.1 - 7.2e-51 172.8 15.2 9.1e-51 172.4 10.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein LVIVD PF08309.6 ETS76372.1 - 0.014 14.3 1.5 3.3 6.7 0.0 3.8 4 0 0 4 4 4 0 LVIVD repeat FAD_binding_4 PF01565.18 ETS76373.1 - 1.7e-18 66.4 0.0 2.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain CorA PF01544.13 ETS76375.1 - 7e-28 97.4 2.4 3.8e-24 85.2 0.7 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein TcpE PF12648.2 ETS76375.1 - 0.65 10.1 2.9 0.44 10.7 0.7 1.6 2 0 0 2 2 2 0 TcpE family AAA_12 PF13087.1 ETS76376.1 - 1.1e-26 93.4 0.0 1.9e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS76376.1 - 7e-24 84.6 0.0 1.4e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS76376.1 - 1.5e-09 37.4 0.1 2.4e-08 33.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS76376.1 - 6.4e-06 25.8 0.7 0.0046 16.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 ETS76376.1 - 9.7e-05 21.8 0.0 0.00074 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 ETS76376.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 ETS76376.1 - 0.00091 20.0 0.1 0.31 11.8 0.0 4.1 4 1 0 4 4 3 1 AAA domain AAA PF00004.24 ETS76376.1 - 0.0027 17.9 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 ETS76376.1 - 0.0054 16.2 0.2 0.41 10.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 ETS76376.1 - 0.0099 16.0 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS76376.1 - 0.013 15.1 0.1 0.45 10.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) SMC_N PF02463.14 ETS76376.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS76376.1 - 0.016 15.1 0.5 0.073 13.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.24 ETS76376.1 - 0.03 13.8 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase DnaB_C PF03796.10 ETS76376.1 - 0.038 12.8 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 ETS76376.1 - 0.047 12.7 0.4 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 ETS76376.1 - 0.061 12.2 0.5 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 ETS76376.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 ETS76376.1 - 0.24 11.5 0.0 0.7 10.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 ETS76376.1 - 0.25 10.1 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 efThoc1 PF11957.3 ETS76377.1 - 1.2e-134 449.5 0.6 1.2e-134 449.5 0.4 2.1 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 ETS76377.1 - 1.2e-33 116.0 0.2 1.2e-33 116.0 0.1 2.3 2 0 0 2 2 1 1 Guanylate kinase MMR_HSR1 PF01926.18 ETS76377.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS76377.1 - 1.3e-05 24.4 0.0 2.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 ETS76377.1 - 0.0001 22.7 0.0 0.00029 21.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 ETS76377.1 - 0.00057 19.8 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS76377.1 - 0.0008 19.5 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS76377.1 - 0.0041 17.1 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETS76377.1 - 0.0049 17.1 0.0 0.0049 17.1 0.0 3.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 ETS76377.1 - 0.0095 15.8 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS76377.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase AAA_17 PF13207.1 ETS76377.1 - 0.021 15.6 2.1 0.09 13.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 ETS76377.1 - 0.097 12.9 1.6 0.47 10.7 1.1 2.3 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETS76377.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MIF4G PF02854.14 ETS76378.1 - 1.5e-49 168.2 0.0 2.6e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 ETS76378.1 - 3.2e-18 65.3 0.4 1.1e-17 63.7 0.2 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 ETS76378.1 - 0.14 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Borrelia_P83 PF05262.6 ETS76378.1 - 5.2 5.2 51.3 0.098 10.9 28.3 2.8 3 0 0 3 3 3 0 Borrelia P83/100 protein DNA_pol_B PF00136.16 ETS76379.1 - 2.6e-112 376.0 1.6 2.6e-112 376.0 1.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 ETS76379.1 - 1.4e-65 220.1 0.4 3.2e-65 219.0 0.1 1.8 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 ETS76379.1 - 9.4e-40 136.4 0.0 1.7e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 ETS76379.1 - 1.7e-23 82.1 14.3 1.9e-23 82.0 6.7 3.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal HEAT_2 PF13646.1 ETS76380.1 - 0.00018 21.6 0.5 0.48 10.7 0.0 4.4 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 ETS76380.1 - 0.00037 20.3 0.9 0.21 11.7 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat DUF2435 PF10363.4 ETS76380.1 - 0.024 14.5 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 ETS76380.1 - 0.027 14.9 7.7 0.25 11.8 0.1 5.3 5 1 1 6 6 6 0 HEAT-like repeat DUF1749 PF08538.5 ETS76381.1 - 2.8e-75 253.0 0.0 3.5e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 ETS76381.1 - 4.3e-11 43.1 0.0 5.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76381.1 - 3.9e-07 29.9 0.0 1.3e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76381.1 - 8.4e-05 22.2 0.1 0.001 18.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 ETS76381.1 - 0.021 14.4 0.0 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase LCAT PF02450.10 ETS76381.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase p450 PF00067.17 ETS76382.1 - 7.7e-46 156.5 0.3 1.3e-44 152.5 0.2 2.0 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 ETS76383.1 - 2.1e-79 266.8 32.3 6.9e-46 156.8 6.2 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS76383.1 - 5.8e-51 172.3 0.1 5.3e-29 101.2 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS76383.1 - 6.7e-11 41.8 3.3 0.0083 15.3 0.0 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS76383.1 - 8.3e-09 35.6 1.3 0.0052 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS76383.1 - 8.9e-06 25.1 0.1 0.024 14.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETS76383.1 - 9.5e-06 25.5 0.0 0.16 11.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 ETS76383.1 - 1.5e-05 24.2 0.2 0.082 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETS76383.1 - 3.4e-05 23.9 0.1 0.38 10.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_23 PF13476.1 ETS76383.1 - 0.00021 21.6 0.2 0.036 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS76383.1 - 0.00025 20.5 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS76383.1 - 0.00025 20.0 0.2 0.042 12.7 0.2 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 ETS76383.1 - 0.00029 21.3 0.4 1.1 9.7 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein AAA_30 PF13604.1 ETS76383.1 - 0.0026 17.3 1.8 0.36 10.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS76383.1 - 0.0053 16.5 1.3 0.37 10.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 ETS76383.1 - 0.011 15.1 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 ETS76383.1 - 0.016 16.0 0.0 7.1 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS76383.1 - 0.019 15.0 0.9 1.6 8.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS76383.1 - 0.022 14.4 0.2 0.11 12.1 0.0 2.3 3 0 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 ETS76383.1 - 0.022 14.1 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 ETS76383.1 - 0.046 12.7 0.1 6.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 ETS76383.1 - 0.05 13.2 0.6 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 ETS76383.1 - 0.054 13.6 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 ETS76383.1 - 0.066 13.0 0.7 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 ETS76383.1 - 0.15 11.7 1.1 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 ETS76383.1 - 0.17 12.1 0.5 30 4.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 ETS76383.1 - 0.19 11.6 0.6 9.5 6.2 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2841 PF11001.3 ETS76384.1 - 2.4e-38 130.8 2.5 3.6e-38 130.2 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) PPR_2 PF13041.1 ETS76385.1 - 4.1e-22 77.9 4.0 5.6e-14 51.8 0.1 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 ETS76385.1 - 8.4e-08 31.9 2.3 0.5 10.7 0.0 7.7 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETS76385.1 - 0.00051 19.4 2.3 1.2 8.6 0.0 4.2 5 0 0 5 5 5 2 PPR repeat PPR PF01535.15 ETS76385.1 - 0.042 13.8 0.1 0.042 13.8 0.0 4.8 6 0 0 6 6 6 0 PPR repeat SNAP PF14938.1 ETS76385.1 - 0.044 12.9 1.3 0.56 9.3 0.1 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DUF1230 PF06799.6 ETS76385.1 - 0.13 12.1 0.4 0.87 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) TPR_12 PF13424.1 ETS76386.1 - 1.6e-23 82.4 0.5 2.2e-12 46.7 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS76386.1 - 1.4e-18 66.1 0.5 9.9e-09 34.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS76386.1 - 0.00013 21.4 0.3 0.26 11.1 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76386.1 - 0.002 17.6 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS76386.1 - 0.0082 15.9 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS76386.1 - 0.0097 15.5 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 ETS76386.1 - 0.012 16.2 0.0 0.41 11.3 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETS76386.1 - 0.027 14.6 0.0 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat 14-3-3 PF00244.15 ETS76386.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 14-3-3 protein PPR PF01535.15 ETS76386.1 - 0.11 12.4 0.3 18 5.6 0.0 2.4 2 0 0 2 2 2 0 PPR repeat AA_permease PF00324.16 ETS76387.1 - 2.5e-134 448.2 37.1 2.9e-134 448.0 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76387.1 - 2.8e-39 134.8 37.8 3.7e-39 134.4 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 ETS76388.1 - 3.9e-38 131.1 0.0 5.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76388.1 - 1.7e-28 99.3 0.0 2.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS76388.1 - 0.00019 20.5 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS76388.1 - 0.0021 17.8 0.2 0.55 9.9 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Lant_dehyd_N PF04737.8 ETS76388.1 - 0.1 12.6 0.1 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Na_H_Exchanger PF00999.16 ETS76389.1 - 7.4e-69 232.0 37.7 9.1e-69 231.7 26.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YajC PF02699.10 ETS76389.1 - 0.18 11.4 3.1 0.44 10.2 0.4 2.8 3 0 0 3 3 3 0 Preprotein translocase subunit MFS_2 PF13347.1 ETS76390.1 - 6.3e-11 41.3 3.4 6.3e-11 41.3 2.3 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 ETS76390.1 - 3e-08 32.7 44.7 3e-06 26.1 19.9 3.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS76390.1 - 0.0055 16.7 1.2 1.8 8.6 0.0 3.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Apolipo_F PF15148.1 ETS76390.1 - 0.2 10.9 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein F DUF3169 PF11368.3 ETS76390.1 - 0.39 9.8 1.6 22 4.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Polysacc_lyase PF14099.1 ETS76391.1 - 0.0066 16.1 7.1 0.011 15.3 4.9 1.4 1 1 0 1 1 1 1 Polysaccharide lyase Velvet PF11754.3 ETS76393.1 - 1.2e-56 191.5 0.0 1.7e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Velvet factor E1_dh PF00676.15 ETS76394.1 - 4.6e-114 380.1 0.3 5.7e-114 379.8 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 ETS76394.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Hemocyanin_C PF03723.9 ETS76394.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Hemocyanin, ig-like domain DUF1770 PF08589.5 ETS76395.1 - 1e-30 106.2 1.4 1.6e-30 105.6 1.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 ETS76396.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 ETS76396.1 - 0.034 12.0 18.6 0.054 11.4 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family eRF1_2 PF03464.10 ETS76397.1 - 4.1e-45 153.3 0.0 7.5e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 ETS76397.1 - 1.4e-40 138.1 0.6 2.7e-40 137.1 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 ETS76397.1 - 1.6e-28 98.9 0.0 2.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 ETS76398.1 - 3.1e-63 212.5 0.1 4e-63 212.2 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 ETS76398.1 - 0.0097 15.3 0.1 0.058 12.8 0.0 2.2 2 0 0 2 2 2 1 ACT domain AMP-binding PF00501.23 ETS76399.1 - 0 1077.2 0.1 1e-83 281.0 0.0 4.5 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 ETS76399.1 - 1.8e-233 772.4 4.1 6e-42 143.5 0.0 7.9 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.20 ETS76399.1 - 4e-54 180.7 2.6 4.1e-14 52.5 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS76399.1 - 7.3e-13 49.2 1.9 0.036 15.0 0.0 5.8 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain AAA_14 PF13173.1 ETS76399.1 - 0.26 11.1 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS76400.1 - 7.3e-45 152.6 0.0 2.1e-25 89.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS76400.1 - 5.1e-32 111.3 41.3 1.9e-27 96.3 13.0 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS76400.1 - 2.4e-13 50.7 0.0 0.0085 16.0 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 ETS76400.1 - 1e-10 41.2 0.0 0.0004 19.6 1.8 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS76400.1 - 2.6e-06 26.8 0.5 0.033 13.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS76400.1 - 3.5e-05 23.8 0.2 0.26 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 ETS76400.1 - 7.4e-05 23.5 0.1 0.28 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS76400.1 - 0.00016 21.1 0.6 0.15 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS76400.1 - 0.00027 21.2 0.4 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS76400.1 - 0.00065 18.9 0.2 0.16 11.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 ETS76400.1 - 0.0008 18.9 0.3 0.5 9.8 0.1 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 ETS76400.1 - 0.0018 17.2 0.1 0.037 12.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS76400.1 - 0.0023 18.0 0.5 3.4 7.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 ETS76400.1 - 0.0024 18.3 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 ETS76400.1 - 0.0034 17.2 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS76400.1 - 0.012 15.7 2.3 0.32 11.2 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 ETS76400.1 - 0.013 15.2 0.2 2.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ETS76400.1 - 0.014 15.3 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 ETS76400.1 - 0.022 15.0 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 ETS76400.1 - 0.023 14.1 1.1 0.082 12.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 ETS76400.1 - 0.027 13.9 0.2 0.84 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 ETS76400.1 - 0.03 13.4 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 ETS76400.1 - 0.031 13.8 0.0 0.99 8.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 ETS76400.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 ETS76400.1 - 0.053 12.1 0.9 0.17 10.4 0.0 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 ETS76400.1 - 0.087 12.7 0.1 3.9 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 ETS76400.1 - 0.23 11.1 0.1 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Drf_FH3 PF06367.11 ETS76402.1 - 0.033 13.5 2.0 0.074 12.4 1.4 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain DUF4570 PF15134.1 ETS76402.1 - 0.099 12.4 1.8 0.13 12.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF948 PF06103.6 ETS76402.1 - 0.14 12.0 5.6 11 5.9 0.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.6 ETS76402.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.5 3 0 0 3 3 3 0 Cytochrome b562 HDV_ag PF01517.13 ETS76402.1 - 0.28 10.8 1.3 0.55 9.8 0.9 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Vps51 PF08700.6 ETS76402.1 - 0.64 9.8 4.5 9.3 6.1 0.1 3.4 3 0 0 3 3 3 0 Vps51/Vps67 SH3_1 PF00018.23 ETS76404.1 - 1.1e-12 47.1 0.1 2.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain bZIP_1 PF00170.16 ETS76404.1 - 2.5e-10 40.1 3.6 2.5e-10 40.1 2.5 2.3 2 0 0 2 2 2 1 bZIP transcription factor SH3_9 PF14604.1 ETS76404.1 - 1.1e-09 37.6 0.1 2.8e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS76404.1 - 4.7e-09 35.5 0.1 8.1e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain bZIP_2 PF07716.10 ETS76404.1 - 2.8e-06 27.0 5.3 2.8e-06 27.0 3.7 2.5 2 0 0 2 2 2 1 Basic region leucine zipper Cullin PF00888.17 ETS76405.1 - 1.1e-128 430.3 2.6 1.7e-128 429.7 1.8 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETS76405.1 - 3.5e-27 94.0 0.9 9.3e-27 92.6 0.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 ETS76405.1 - 0.039 13.8 0.1 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 HbrB-like DUF2235 PF09994.4 ETS76407.1 - 6.6e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 ETS76407.1 - 0.00035 21.0 0.0 0.001 19.5 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS76407.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS76407.1 - 0.0032 16.6 0.1 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETS76407.1 - 0.074 13.3 0.1 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain FSH1 PF03959.8 ETS76407.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AAA_17 PF13207.1 ETS76407.1 - 2.1 9.1 10.5 2.9 8.7 3.5 3.6 3 1 0 3 3 3 0 AAA domain Glyco_transf_22 PF03901.12 ETS76408.1 - 6.8e-76 255.9 14.5 8.7e-76 255.5 10.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 ETS76408.1 - 0.01 15.7 15.0 0.036 13.9 1.1 3.6 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Aminotran_3 PF00202.16 ETS76409.1 - 4.1e-109 364.5 0.0 5e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 ETS76409.1 - 4.6e-06 25.9 0.0 7.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 ETS76409.1 - 0.00026 20.0 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3543 PF12063.3 ETS76410.1 - 1.8e-92 308.9 3.3 2.9e-92 308.1 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 ETS76410.1 - 5.8e-60 202.6 0.0 1.1e-59 201.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76410.1 - 7.8e-41 139.8 0.0 1.8e-40 138.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS76410.1 - 0.0025 16.8 0.1 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Utp11 PF03998.8 ETS76410.1 - 0.19 11.5 3.6 0.47 10.2 2.5 1.6 1 0 0 1 1 1 0 Utp11 protein RhoGAP PF00620.22 ETS76411.1 - 1.5e-39 135.0 0.0 2.6e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.11 ETS76412.1 - 6.1e-18 64.6 15.0 6.1e-18 64.6 10.4 1.9 2 1 1 3 3 3 1 Major Facilitator Superfamily SdpI PF13630.1 ETS76412.1 - 0.048 13.3 0.6 0.048 13.3 0.4 3.6 2 1 1 4 4 4 0 SdpI/YhfL protein family DUF4231 PF14015.1 ETS76412.1 - 4 7.4 7.9 1.7 8.6 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Aa_trans PF01490.13 ETS76413.1 - 8.8e-30 103.4 35.6 1e-29 103.2 24.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short_C2 PF13561.1 ETS76414.1 - 1.2e-24 87.4 0.0 1.5e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS76414.1 - 7.6e-21 74.7 0.0 1.3e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76414.1 - 3.3e-07 30.1 0.0 1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS76414.1 - 0.0051 16.2 0.3 0.027 13.8 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 ETS76414.1 - 0.035 14.3 0.1 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.12 ETS76414.1 - 0.061 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.3 ETS76415.1 - 1.3e-42 145.8 7.5 2.3e-42 144.9 5.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76415.1 - 2.9e-14 52.6 26.8 4.3e-08 32.9 8.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TMV_coat PF00721.16 ETS76415.1 - 0.082 12.8 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) DUF1479 PF07350.7 ETS76416.1 - 1.3e-08 33.7 0.0 0.00084 17.9 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS76416.1 - 3.4e-07 30.5 0.0 4.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 ETS76417.1 - 3e-69 233.7 25.9 3.6e-69 233.4 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76417.1 - 1.2e-22 80.1 23.7 1.2e-22 80.1 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 ETS76418.1 - 1.6e-12 47.6 0.0 3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76418.1 - 0.00037 20.2 0.0 0.00084 19.0 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS76418.1 - 0.0074 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TIR-like PF10137.4 ETS76418.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain FAD_binding_4 PF01565.18 ETS76420.1 - 1.9e-18 66.2 1.8 5e-18 64.9 1.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS76420.1 - 1.8e-12 46.9 0.1 1.8e-12 46.9 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like DUF3579 PF12112.3 ETS76420.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Cytokin-bind PF09265.5 ETS76420.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ank_2 PF12796.2 ETS76421.1 - 0.0079 16.5 0.0 0.68 10.3 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Glyco_hydro_18 PF00704.23 ETS76422.1 - 0.0011 18.4 0.3 0.0017 17.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4132 PF13569.1 ETS76422.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4132) F-box PF00646.28 ETS76422.1 - 0.0012 18.4 0.5 0.0039 16.8 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS76422.1 - 0.0074 15.9 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Syntaxin-6_N PF09177.6 ETS76423.1 - 0.2 12.0 2.7 0.36 11.2 0.1 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal TPR_10 PF13374.1 ETS76425.1 - 1.8e-37 126.1 9.2 2.5e-09 36.7 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETS76425.1 - 3.2e-32 110.2 7.1 1.1e-12 47.7 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS76425.1 - 2e-07 30.4 2.6 3.9 7.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS76425.1 - 7.4e-06 25.5 0.4 0.0014 18.2 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 ETS76425.1 - 2e-05 25.1 3.2 0.47 11.1 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76425.1 - 0.00011 21.6 0.1 4.4 7.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS76425.1 - 0.00019 21.3 0.0 9.4 6.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS76425.1 - 0.00056 19.5 10.1 1.6 8.7 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76425.1 - 0.0078 15.9 3.0 12 5.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS76425.1 - 0.021 14.9 0.5 0.94 9.6 0.0 3.4 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-Di19 PF05605.7 ETS76425.1 - 0.024 14.7 3.6 5 7.3 0.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TPR_4 PF07721.9 ETS76425.1 - 0.036 14.4 0.4 32 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 ETS76425.1 - 0.06 13.7 12.9 0.13 12.6 0.0 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS76425.1 - 0.072 13.4 12.3 3.7 8.1 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS76425.1 - 0.3 11.4 2.7 23 5.5 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_hydro_18 PF00704.23 ETS76426.1 - 7.1e-74 249.2 5.0 1e-73 248.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 ETS76428.1 - 5.6e-14 52.2 0.5 1e-11 45.0 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS76428.1 - 2.2e-11 43.9 4.7 0.0006 20.2 0.1 4.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76428.1 - 1.7e-08 34.4 1.8 0.00011 22.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76428.1 - 2.6e-08 33.3 1.9 0.001 19.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 ETS76428.1 - 8.4e-08 31.6 2.5 3.9e-05 23.2 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat LysM PF01476.15 ETS76429.1 - 1.4e-17 63.2 0.3 0.0001 22.1 0.0 5.6 5 0 0 5 5 5 4 LysM domain LysM PF01476.15 ETS76430.1 - 7.5e-17 60.9 1.1 0.00023 20.9 0.0 5.7 5 1 1 6 6 6 5 LysM domain ABC_tran PF00005.22 ETS76431.1 - 4.7e-43 146.7 0.0 6e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS76431.1 - 6.9e-35 120.7 31.8 7.3e-20 71.5 8.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS76431.1 - 4e-11 42.5 1.0 0.1 11.8 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS76431.1 - 2.7e-08 34.1 0.0 0.047 13.6 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 ETS76431.1 - 1e-06 28.8 1.0 0.0031 17.5 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 ETS76431.1 - 3.9e-06 26.3 0.8 0.056 12.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS76431.1 - 1.4e-05 25.5 0.5 0.011 16.1 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS76431.1 - 1.8e-05 24.8 0.3 0.27 11.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS76431.1 - 6.9e-05 22.3 0.1 0.054 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS76431.1 - 0.0002 21.0 2.5 0.0052 16.5 0.3 3.2 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 ETS76431.1 - 0.00029 20.3 1.1 0.0053 16.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 ETS76431.1 - 0.00047 19.3 0.2 0.19 10.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS76431.1 - 0.00054 19.5 0.2 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 ETS76431.1 - 0.00067 18.6 0.0 0.03 13.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 ETS76431.1 - 0.0011 18.5 3.2 1.6 8.2 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETS76431.1 - 0.0014 19.4 0.0 3 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS76431.1 - 0.0016 18.3 0.1 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 ETS76431.1 - 0.0017 18.2 0.7 0.038 13.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA PF00004.24 ETS76431.1 - 0.004 17.3 0.0 1.8 8.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 ETS76431.1 - 0.0069 16.8 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 ETS76431.1 - 0.0088 15.5 0.2 0.4 10.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 ETS76431.1 - 0.0093 15.0 2.3 0.26 10.3 0.1 2.6 3 0 0 3 3 2 1 Zeta toxin Arch_ATPase PF01637.13 ETS76431.1 - 0.017 14.8 3.6 0.044 13.4 0.0 2.9 4 0 0 4 4 3 0 Archaeal ATPase MobB PF03205.9 ETS76431.1 - 0.029 14.0 0.3 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS76431.1 - 0.055 13.3 0.0 4.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 ETS76431.1 - 0.058 13.0 2.7 0.71 9.5 0.2 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 ETS76431.1 - 0.072 12.7 0.9 5.3 6.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 ETS76431.1 - 0.074 12.6 0.2 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS76431.1 - 0.11 12.8 0.2 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 ETS76431.1 - 0.11 11.1 1.8 1.1 7.7 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 ETS76431.1 - 0.13 12.0 0.6 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 ETS76431.1 - 0.35 9.8 0.4 19 4.0 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 ETS76431.1 - 0.4 10.3 1.5 2.9 7.5 0.1 2.6 3 0 0 3 3 3 0 NTPase Zn_clus PF00172.13 ETS76432.1 - 5.1e-08 32.7 11.7 1e-07 31.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 ETS76433.1 - 2.3e-29 103.1 3.5 3.1e-29 102.6 2.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS76433.1 - 8.3e-13 48.9 5.8 5.6e-12 46.2 4.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS76433.1 - 1.8e-07 30.7 8.0 1.4e-06 27.8 3.6 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS76433.1 - 8.1e-05 22.3 1.6 0.00026 20.7 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase Peptidase_S10 PF00450.17 ETS76434.1 - 7.2e-87 292.2 0.0 9e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS76434.1 - 0.022 14.6 0.1 0.12 12.2 0.1 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS76434.1 - 0.18 10.4 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S10 PF00450.17 ETS76435.1 - 1.3e-51 176.1 0.0 1.5e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS76435.1 - 0.017 15.0 0.1 0.035 13.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribonuc_L-PSP PF01042.16 ETS76436.1 - 2.2e-27 95.2 0.0 2.4e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 ETS76437.1 - 1.6e-18 66.6 49.8 1.3e-11 43.8 21.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.5 ETS76437.1 - 2.4 8.2 6.6 7.6 6.6 0.0 3.4 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Aminotran_1_2 PF00155.16 ETS76438.1 - 2.1e-42 145.3 0.0 2.7e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 ETS76438.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.16 ETS76438.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_S10 PF00450.17 ETS76439.1 - 6.4e-78 262.7 0.0 8.3e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Amidohydro_1 PF01979.15 ETS76440.1 - 2e-30 106.5 0.0 2.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS76440.1 - 3e-12 47.1 0.6 1.6e-11 44.7 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS76440.1 - 1.3e-08 34.5 0.0 4.5e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS76440.1 - 6.6e-05 22.2 0.3 9.5e-05 21.7 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Peptidase_S10 PF00450.17 ETS76441.1 - 2.4e-33 115.9 0.0 2.4e-32 112.6 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase PEP_mutase PF13714.1 ETS76442.1 - 3e-50 170.6 0.8 3.5e-50 170.4 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETS76442.1 - 1.9e-20 72.6 1.8 4.2e-20 71.4 1.4 1.5 2 0 0 2 2 2 1 Isocitrate lyase family Zeta_toxin PF06414.7 ETS76443.1 - 1.5e-39 135.2 0.0 2.1e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ETS76443.1 - 0.03 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2827 PF10933.3 ETS76443.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Opy2 PF09463.5 ETS76444.1 - 3 8.0 13.7 2.3 8.3 6.6 2.5 2 1 0 2 2 2 0 Opy2 protein BTB PF00651.26 ETS76446.1 - 6.8e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 ETS76447.1 - 2e-06 27.3 0.6 7.5e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS76447.1 - 0.0048 16.5 0.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 ETS76447.1 - 0.32 10.6 3.7 32 4.2 0.0 3.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) p450 PF00067.17 ETS76448.1 - 7e-55 186.3 0.0 9.8e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 ETS76449.1 - 0.00032 20.6 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.13 ETS76450.1 - 0.018 14.9 5.2 0.99 9.3 0.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.9 ETS76450.1 - 0.071 12.6 0.4 0.33 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) DUF3505 PF12013.3 ETS76450.1 - 0.1 12.8 3.1 0.9 9.8 0.2 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3505) RNA_pol_I_A49 PF06870.7 ETS76451.1 - 1.1e-72 244.8 0.0 1.4e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor GARS_A PF01071.14 ETS76455.1 - 2.8e-81 271.7 0.0 4.9e-81 270.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 ETS76455.1 - 9.3e-35 119.0 0.0 2.7e-34 117.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 ETS76455.1 - 4.8e-30 104.5 0.1 1.2e-29 103.2 0.0 1.7 2 0 0 2 2 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 ETS76455.1 - 4.4e-26 90.8 0.2 9.1e-26 89.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 ETS76455.1 - 1.3e-16 60.5 1.6 4.8e-16 58.7 1.1 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 ETS76455.1 - 3.7e-14 52.8 0.0 8.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS76455.1 - 1.8e-08 33.5 0.0 4.5e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ETS76455.1 - 2.3e-06 27.0 0.0 4.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ETS76455.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 ETS76455.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 ETS76455.1 - 0.0051 16.2 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 ETS76455.1 - 0.02 14.3 0.1 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CoaE PF01121.15 ETS76456.1 - 2.9e-43 147.3 0.0 9.9e-43 145.6 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 ETS76456.1 - 0.0012 19.6 0.3 0.01 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS76456.1 - 0.006 16.8 1.2 0.27 11.5 0.1 2.6 3 0 0 3 3 3 1 AAA domain FixP_N PF14715.1 ETS76456.1 - 0.032 13.6 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Tox-ART-HYD1 PF15633.1 ETS76456.1 - 0.077 13.8 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase AAA_33 PF13671.1 ETS76456.1 - 0.085 12.7 0.0 0.89 9.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain SKI PF01202.17 ETS76456.1 - 0.14 12.0 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase eIF-5_eIF-2B PF01873.12 ETS76458.1 - 1.8e-36 124.5 0.0 3.7e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 ETS76458.1 - 6.1e-21 74.1 4.9 1e-20 73.4 1.1 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3797 PF12677.2 ETS76458.1 - 0.00023 20.7 0.8 0.00067 19.2 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) HLH PF00010.21 ETS76459.1 - 2.4e-12 46.3 0.2 6.3e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 ETS76459.1 - 0.14 11.6 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein CLTH PF10607.4 ETS76460.1 - 4.4e-30 104.2 0.0 6.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 ETS76460.1 - 0.032 14.0 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 LisH Cep57_CLD PF14073.1 ETS76460.1 - 0.033 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CAF1 PF04857.15 ETS76461.1 - 5.1e-62 209.5 0.0 7.1e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 ETS76462.1 - 2.6e-17 62.2 0.7 4e-17 61.6 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Phage_GPO PF05929.6 ETS76463.1 - 0.021 14.0 6.5 0.042 13.1 4.5 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4527 PF15030.1 ETS76463.1 - 0.11 11.8 12.8 0.018 14.3 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Atg14 PF10186.4 ETS76463.1 - 2.4 7.0 8.6 4.1 6.2 6.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IFT20 PF14931.1 ETS76463.1 - 6.2 6.7 15.1 2.7 7.9 2.0 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Pyr_redox_2 PF07992.9 ETS76464.1 - 2.3e-14 53.7 0.0 1.4e-13 51.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76464.1 - 2.6e-12 46.9 0.6 3.5e-09 36.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS76464.1 - 4.3e-09 35.7 4.7 0.035 13.0 0.1 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS76464.1 - 3.7e-07 30.3 0.1 0.0027 17.7 0.0 3.0 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS76464.1 - 3.1e-06 27.0 2.3 0.14 11.9 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS76464.1 - 0.002 17.1 0.4 1.4 7.7 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS76464.1 - 0.0064 15.3 1.2 0.18 10.6 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 ETS76464.1 - 0.017 15.1 0.2 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS76464.1 - 0.02 13.8 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS76464.1 - 0.02 13.5 7.6 0.029 12.9 0.4 2.7 3 1 0 3 3 3 0 Tryptophan halogenase PH_7 PF15408.1 ETS76464.1 - 0.05 13.4 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain FAD_oxidored PF12831.2 ETS76464.1 - 0.089 11.8 0.4 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 ETS76465.1 - 9.4e-11 41.0 0.0 1.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76465.1 - 4.8e-09 35.9 9.3 9.4e-09 35.0 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 ETS76466.1 - 8e-15 55.8 0.1 1.8e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS76466.1 - 1.7e-13 50.2 0.1 1.3e-12 47.3 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS76466.1 - 5.2e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 ETS76466.1 - 6.2e-05 23.2 0.2 0.00031 21.0 0.1 2.1 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS76466.1 - 0.0046 16.9 0.3 0.0093 15.9 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 ETS76466.1 - 0.061 13.2 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 ETS76466.1 - 0.075 12.2 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Cupin_2 PF07883.6 ETS76467.1 - 6.8e-09 35.1 0.2 1.2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS76467.1 - 0.0069 15.8 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.2 ETS76467.1 - 0.059 13.2 0.1 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain AraC_binding PF02311.14 ETS76467.1 - 0.067 12.8 0.1 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Peptidase_M28 PF04389.12 ETS76468.1 - 9.4e-26 90.6 0.1 2e-25 89.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS76468.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 ETS76468.1 - 0.002 16.9 0.0 0.0037 16.0 0.0 1.4 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase fn3 PF00041.16 ETS76468.1 - 0.0037 17.3 0.1 0.0082 16.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain GMC_oxred_N PF00732.14 ETS76469.1 - 3.9e-32 111.5 0.0 1.3e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS76469.1 - 6.1e-18 65.4 0.6 1.1e-17 64.6 0.4 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS76469.1 - 2.3e-14 53.0 0.7 1.1e-06 27.8 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS76469.1 - 6.8e-08 31.7 0.1 0.00072 18.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 ETS76469.1 - 1.1e-06 27.4 0.3 7.9e-06 24.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS76469.1 - 4.6e-06 26.5 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS76469.1 - 2e-05 24.5 0.8 7.9e-05 22.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS76469.1 - 2.7e-05 23.4 0.5 0.0028 16.8 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS76469.1 - 4.9e-05 22.4 0.1 8.1e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETS76469.1 - 0.00087 18.4 0.9 0.0022 17.1 0.2 2.0 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS76469.1 - 0.00089 19.3 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS76469.1 - 0.0013 17.8 0.1 0.0029 16.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETS76469.1 - 0.0028 18.0 0.3 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS76469.1 - 0.014 15.1 0.1 0.066 12.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS76469.1 - 0.027 13.1 0.1 0.041 12.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 ETS76469.1 - 0.027 13.3 0.1 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SBP_bac_1 PF01547.20 ETS76469.1 - 0.027 14.1 1.5 0.029 14.0 0.2 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein VirE PF05272.6 ETS76470.1 - 0.0051 16.2 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Virulence-associated protein E CorA PF01544.13 ETS76471.1 - 0.076 12.0 15.8 2.6 6.9 11.0 2.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2_4 PF13894.1 ETS76472.1 - 0.012 15.9 0.4 0.026 14.8 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS76472.1 - 0.051 13.9 0.3 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 ETS76472.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC_tran PF00005.22 ETS76473.1 - 7.3e-34 117.0 0.0 5.4e-17 62.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS76473.1 - 2.9e-13 50.4 5.9 0.011 15.7 0.0 4.5 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 ETS76473.1 - 1.1e-12 47.7 1.2 0.00011 21.4 0.0 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 ETS76473.1 - 1.6e-12 46.7 5.0 1.6e-12 46.7 3.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.1 ETS76473.1 - 2.6e-07 30.0 0.2 0.15 11.0 0.1 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 ETS76473.1 - 7.6e-07 29.9 1.2 0.053 14.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 ETS76473.1 - 1.2e-06 28.7 0.2 0.0088 16.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS76473.1 - 1.7e-06 28.1 0.0 0.0015 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 ETS76473.1 - 3.8e-05 23.0 2.8 3.8e-05 23.0 1.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 ETS76473.1 - 6.4e-05 22.4 0.2 0.076 12.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 ETS76473.1 - 6.8e-05 22.5 1.1 0.046 13.3 0.0 2.7 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.17 ETS76473.1 - 8.1e-05 22.7 0.2 0.095 12.8 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.1 ETS76473.1 - 9.5e-05 22.8 1.0 0.0094 16.2 0.9 2.6 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETS76473.1 - 0.00011 21.8 0.3 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 ETS76473.1 - 0.00011 21.4 1.2 0.56 9.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS76473.1 - 0.00011 22.1 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS76473.1 - 0.00015 21.2 0.2 0.59 9.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 ETS76473.1 - 0.00026 20.6 1.0 0.071 12.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 ETS76473.1 - 0.00036 20.8 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 ETS76473.1 - 0.00058 19.3 3.4 0.045 13.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.1 ETS76473.1 - 0.00089 19.0 10.3 0.0018 18.0 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 ETS76473.1 - 0.0011 18.5 0.1 2.1 7.7 0.0 2.9 3 0 0 3 3 2 2 Virulence-associated protein E Miro PF08477.8 ETS76473.1 - 0.0025 18.2 0.2 0.97 9.9 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_13 PF13166.1 ETS76473.1 - 0.0037 15.7 0.0 0.0037 15.7 0.0 2.4 4 0 0 4 4 3 1 AAA domain Fer4_6 PF12837.2 ETS76473.1 - 0.0056 16.5 1.0 0.0056 16.5 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 ETS76473.1 - 0.0091 15.9 0.1 5.3 6.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 ETS76473.1 - 0.012 15.6 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 ETS76473.1 - 0.018 14.4 0.8 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.1 ETS76473.1 - 0.037 13.6 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS76473.1 - 0.072 12.8 1.3 2.4 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 ETS76473.1 - 0.074 12.0 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 ETS76473.1 - 0.089 11.6 0.0 6.5 5.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 ETS76473.1 - 0.094 12.6 0.0 9 6.2 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 ETS76473.1 - 0.097 12.5 1.3 18 5.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.10 ETS76473.1 - 0.099 11.3 0.1 1.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 ETS76473.1 - 0.11 11.3 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_8 PF13183.1 ETS76473.1 - 0.13 12.3 8.4 0.33 11.0 5.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 ETS76473.1 - 0.14 12.9 0.2 0.14 12.9 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NTPase_1 PF03266.10 ETS76473.1 - 0.14 11.8 3.3 4 7.1 0.0 2.7 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.1 ETS76473.1 - 0.26 10.8 0.0 0.26 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 ETS76473.1 - 0.26 10.7 1.8 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 ETS76473.1 - 0.58 9.5 2.8 15 4.8 0.0 2.7 3 0 0 3 3 2 0 AAA-like domain Fer4_2 PF12797.2 ETS76473.1 - 0.96 9.4 12.1 0.92 9.5 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 ETS76473.1 - 1.1 9.1 14.7 0.069 12.9 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 ETS76473.1 - 2 8.8 13.5 0.11 12.9 1.6 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 ETS76473.1 - 7.8 6.8 14.5 0.18 12.0 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain BTB PF00651.26 ETS76474.1 - 1.7e-05 24.7 0.0 4.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 ETS76475.1 - 8.4e-18 64.1 1.3 1.4e-17 63.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76475.1 - 2.9e-08 33.4 9.9 5.4e-08 32.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS76476.1 - 2e-41 141.9 19.9 2e-41 141.9 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76476.1 - 7.2e-12 44.6 9.2 7.2e-12 44.6 6.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS76476.1 - 0.0002 19.6 4.1 0.00033 18.9 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.17 ETS76477.1 - 5.1e-33 113.9 0.2 6.7e-33 113.6 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aldedh PF00171.17 ETS76478.1 - 1.8e-133 445.2 0.0 2.2e-133 444.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS76478.1 - 0.0047 15.7 0.0 0.02 13.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) p450 PF00067.17 ETS76480.1 - 6.5e-21 74.3 0.0 2.1e-17 62.7 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 DUF1633 PF07794.6 ETS76480.1 - 0.25 9.2 0.0 0.37 8.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Cupin_2 PF07883.6 ETS76481.1 - 2.6e-08 33.2 0.3 5e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 ETS76482.1 - 1.9e-31 109.2 19.3 2.5e-31 108.8 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.18 ETS76483.1 - 1.8e-29 102.0 0.8 2.8e-29 101.3 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 ETS76484.1 - 8.6e-05 22.5 3.0 0.00088 19.2 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 ETS76484.1 - 0.00042 20.0 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 ETS76484.1 - 0.045 12.6 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein p450 PF00067.17 ETS76485.1 - 6.7e-42 143.5 0.0 9.8e-41 139.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS76486.1 - 1.6e-22 80.1 0.0 2.7e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS76487.1 - 1.6e-38 132.3 42.6 4.6e-38 130.8 29.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS76487.1 - 2e-17 62.6 15.9 2.5e-17 62.3 11.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS76487.1 - 5.8e-16 58.1 29.9 8.8e-16 57.5 8.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3810 PF12725.2 ETS76487.1 - 0.62 8.9 2.2 1 8.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Zn_clus PF00172.13 ETS76488.1 - 1e-05 25.3 10.3 2.3e-05 24.1 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 ETS76489.1 - 4.3e-30 104.6 0.0 5.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 ETS76489.1 - 1.7e-05 24.1 0.1 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 ETS76489.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TFIIE_alpha PF02002.12 ETS76489.1 - 0.019 14.4 0.1 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit CheR PF01739.13 ETS76489.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MarR_2 PF12802.2 ETS76489.1 - 0.069 12.8 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_AsnC-type PF13404.1 ETS76489.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Methyltransf_18 PF12847.2 ETS76489.1 - 0.081 13.5 0.0 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF2805 PF10985.3 ETS76489.1 - 0.084 12.8 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Cupin_3 PF05899.7 ETS76490.1 - 0.008 15.5 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 ETS76490.1 - 0.21 11.0 2.0 7.3 6.1 1.4 2.2 1 1 0 1 1 1 0 Cupin domain Sugar_tr PF00083.19 ETS76492.1 - 6.9e-72 242.4 24.8 8e-72 242.2 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76492.1 - 1.1e-14 53.9 23.4 1.1e-14 53.9 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 ETS76494.1 - 3e-73 247.2 5.3 4.8e-73 246.5 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS76494.1 - 4e-09 36.3 17.3 4e-09 36.3 12.0 4.0 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 ETS76495.1 - 1.5e-25 88.8 0.2 7.1e-07 29.0 0.0 5.7 5 0 0 5 5 5 4 LysM domain Methyltransf_2 PF00891.13 ETS76496.1 - 2.5e-40 138.2 0.0 3.3e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS76496.1 - 0.0002 21.9 0.0 0.00041 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76496.1 - 0.033 14.6 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS76496.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.2 ETS76497.1 - 3.7e-24 84.8 0.0 7.7e-12 45.3 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76497.1 - 6.8e-24 82.4 0.2 2.4e-08 33.3 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETS76497.1 - 3.3e-15 55.7 3.1 1.6e-06 28.1 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76497.1 - 2e-13 50.4 0.6 0.0002 21.7 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76497.1 - 4.2e-09 35.7 0.2 2.1e-05 24.3 0.0 4.8 4 0 0 4 4 3 1 Ankyrin repeat AAA_16 PF13191.1 ETS76497.1 - 3.1e-08 33.8 0.3 1.6e-07 31.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ETS76497.1 - 1.4e-07 31.3 0.0 3.8e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS76497.1 - 1.8e-05 24.9 0.0 6.2e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS76497.1 - 2.8e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 ETS76497.1 - 0.0016 18.1 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS76497.1 - 0.0017 18.5 0.0 0.0052 16.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 ETS76497.1 - 0.0017 18.5 0.1 0.015 15.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS76497.1 - 0.0037 16.1 0.4 0.048 12.5 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 ETS76497.1 - 0.011 15.5 0.1 0.42 10.5 0.0 2.9 1 1 0 1 1 1 0 AAA domain TPR_12 PF13424.1 ETS76497.1 - 0.041 13.8 0.3 0.97 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS76497.1 - 0.05 13.5 0.5 20 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_13 PF13166.1 ETS76497.1 - 0.17 10.3 0.1 3 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 ETS76497.1 - 0.47 9.3 5.0 4.8 6.0 0.0 3.3 3 1 1 4 4 4 0 KAP family P-loop domain Lipase_GDSL_2 PF13472.1 ETS76498.1 - 7.2e-11 42.5 0.0 9.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS76498.1 - 0.17 11.6 0.0 0.49 10.1 0.0 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DCA16 PF15349.1 ETS76499.1 - 0.043 13.1 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 HILPDA PF15220.1 ETS76500.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated INTS5_N PF14837.1 ETS76500.1 - 0.22 10.8 0.2 1.3 8.4 0.1 2.0 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus NACHT PF05729.7 ETS76501.1 - 7e-06 25.8 1.1 0.073 12.7 0.0 3.1 2 1 1 3 3 3 2 NACHT domain Ank_4 PF13637.1 ETS76501.1 - 4.8e-05 23.7 0.0 0.00093 19.6 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76501.1 - 0.00056 20.0 0.0 0.03 14.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 ETS76501.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 ETS76501.1 - 0.0077 16.5 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_10 PF12846.2 ETS76501.1 - 0.034 13.5 0.0 0.17 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain Ank PF00023.25 ETS76501.1 - 0.049 13.4 0.0 13 5.8 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 ETS76501.1 - 0.089 13.0 0.0 36 5.0 0.0 3.6 3 0 0 3 3 2 0 Ankyrin repeat RNA_helicase PF00910.17 ETS76501.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 ETS76501.1 - 0.14 13.0 0.0 0.57 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS76501.1 - 0.16 12.2 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 ETS76502.1 - 1.7e-33 114.3 10.3 1.8e-11 43.7 0.8 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS76502.1 - 9.4e-22 76.4 4.3 6.7e-10 38.4 0.0 4.5 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 ETS76502.1 - 9.8e-22 75.0 7.4 2.1e-05 24.0 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76502.1 - 3.8e-18 64.2 8.3 6.7e-05 22.3 0.1 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETS76502.1 - 2.2e-13 49.6 14.6 0.00072 19.3 0.0 7.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76502.1 - 2.2e-13 48.9 6.1 0.0046 16.6 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 ETS76502.1 - 1.4e-12 47.0 0.0 6.6e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_7 PF13176.1 ETS76502.1 - 1.3e-11 43.3 2.8 0.0043 16.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS76502.1 - 1.5e-11 44.6 0.8 1.1e-06 29.1 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS76502.1 - 6e-08 32.6 2.8 0.43 11.3 0.1 6.3 4 2 3 7 7 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS76502.1 - 1.6e-07 31.3 1.0 0.12 12.8 0.0 5.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS76502.1 - 3.9e-07 30.3 1.4 0.017 15.4 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS76502.1 - 7.3e-07 28.9 0.0 0.25 11.6 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS76502.1 - 2.5e-05 24.2 0.2 0.34 11.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 ETS76502.1 - 7.4e-05 22.8 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_21 PF09976.4 ETS76502.1 - 8.2e-05 22.5 0.0 0.00031 20.7 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS76502.1 - 0.00097 19.2 0.3 0.1 12.7 0.0 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 ETS76502.1 - 0.0062 16.3 1.0 0.022 14.6 0.1 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_9 PF13371.1 ETS76502.1 - 0.0066 16.2 2.1 0.097 12.5 0.2 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_14 PF13173.1 ETS76502.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2225 PF09986.4 ETS76502.1 - 0.041 13.3 1.8 1.2 8.6 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 ETS76502.1 - 0.052 13.4 0.7 4.5 7.2 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF1128 PF06569.6 ETS76502.1 - 0.088 12.5 0.2 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Tax PF02959.11 ETS76502.1 - 0.13 11.6 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax DUF1717 PF05414.6 ETS76503.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) UPF0242 PF06785.6 ETS76506.1 - 0.022 13.4 1.6 0.039 12.6 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Rho_Binding PF08912.6 ETS76506.1 - 0.19 12.0 4.7 0.16 12.2 1.4 2.3 2 0 0 2 2 2 0 Rho Binding Glyco_hydro_61 PF03443.9 ETS76507.1 - 6.4e-40 137.2 0.0 1e-39 136.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydantoinase_B PF02538.9 ETS76508.1 - 6.3e-180 598.8 0.0 8.7e-180 598.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS76508.1 - 3e-95 318.6 0.0 6e-95 317.6 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS76508.1 - 9.2e-58 194.6 0.7 4.4e-56 189.1 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 ETS76508.1 - 0.027 13.7 0.2 0.08 12.2 0.2 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Phage_Mu_Gp45 PF06890.7 ETS76508.1 - 0.064 12.7 0.3 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein FA_desaturase PF00487.19 ETS76509.1 - 0.17 11.3 3.2 0.38 10.1 2.2 1.6 1 1 0 1 1 1 0 Fatty acid desaturase DUF4395 PF14340.1 ETS76509.1 - 0.17 11.9 3.3 0.094 12.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) ABC2_membrane_2 PF12679.2 ETS76509.1 - 0.26 10.0 2.0 0.37 9.6 0.2 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.1 ETS76509.1 - 0.47 9.8 7.4 1.7 8.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TctB PF07331.6 ETS76509.1 - 1 8.9 6.4 3.3 7.3 0.2 2.3 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family T5orf172 PF10544.4 ETS76510.1 - 3.5e-14 52.9 0.1 9.3e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 ETS76510.1 - 1.4e-11 44.7 0.7 3e-11 43.6 0.5 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 eIF-6 PF01912.13 ETS76511.1 - 1.9e-83 278.4 1.0 2.4e-83 278.0 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family ThiF PF00899.16 ETS76513.1 - 3.7e-17 62.4 0.0 7.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Cytochrom_C552 PF02335.10 ETS76514.1 - 0.099 11.3 2.3 0.19 10.4 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c552 HD_3 PF13023.1 ETS76514.1 - 2.1 8.0 11.2 0.83 9.3 2.8 2.2 2 0 0 2 2 2 0 HD domain DUF2431 PF10354.4 ETS76515.1 - 1e-55 188.1 0.0 1.3e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Bac_luciferase PF00296.15 ETS76516.1 - 2.3e-63 214.1 0.0 2.8e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CDI PF02234.14 ETS76516.1 - 0.12 12.2 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Pectate_lyase_3 PF12708.2 ETS76517.1 - 7.7e-83 278.0 17.8 1.3e-68 231.4 8.0 3.8 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 ETS76517.1 - 6.5e-06 25.5 3.6 0.033 13.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Scs3p PF10261.4 ETS76518.1 - 2.6e-63 213.2 5.7 4.1e-63 212.6 3.9 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM VPS9 PF02204.13 ETS76519.1 - 1.6e-24 85.9 0.0 3.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 ETS76520.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 ETS76520.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 ETS76520.1 - 0.0041 16.8 0.1 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS76520.1 - 0.014 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 ETS76520.1 - 0.037 13.8 0.1 0.083 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family CH PF00307.26 ETS76521.1 - 4.2e-38 129.7 0.1 9.1e-19 67.5 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 ETS76521.1 - 2e-25 88.5 0.4 6e-25 87.0 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 ETS76521.1 - 1.6e-13 50.1 0.3 1.2e-07 31.2 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 ETS76521.1 - 6.6e-06 25.5 0.2 0.0015 18.2 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 ETS76521.1 - 3.9e-05 23.1 1.8 0.0021 17.6 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETS76521.1 - 7.4e-05 21.7 0.1 0.022 14.0 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 ETS76521.1 - 0.00033 20.7 3.7 0.00041 20.4 1.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair DUF1943 PF09172.6 ETS76521.1 - 0.0023 16.8 0.9 0.0057 15.5 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) EF-hand_5 PF13202.1 ETS76521.1 - 0.098 12.0 0.3 0.37 10.2 0.1 2.1 2 0 0 2 2 2 0 EF hand Sipho_Gp157 PF05565.6 ETS76521.1 - 0.16 11.5 5.2 4.5 6.8 0.7 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 Spectrin PF00435.16 ETS76521.1 - 0.5 10.6 6.2 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Spectrin repeat FAD-oxidase_C PF02913.14 ETS76522.1 - 2.6e-59 200.5 0.0 3.9e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS76522.1 - 2.8e-36 124.0 0.2 5.3e-36 123.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain zf-Tim10_DDP PF02953.10 ETS76523.1 - 1.8e-21 75.1 3.1 2.4e-21 74.7 2.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 ETS76524.1 - 1.3e-20 73.1 14.1 2.3e-20 72.3 6.6 2.3 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 ETS76524.1 - 8.7e-16 57.6 0.6 8.7e-16 57.6 0.4 1.7 2 1 0 2 2 2 1 Ribosomal protein L23 DUF3321 PF11968.3 ETS76525.1 - 5.9e-91 303.9 0.0 7.3e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 ETS76525.1 - 0.00025 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2989 PF11207.3 ETS76525.1 - 0.08 12.3 0.7 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) HAD_2 PF13419.1 ETS76526.1 - 2e-30 106.2 0.0 3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS76526.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS76526.1 - 0.018 14.7 0.0 0.058 13.1 0.0 1.9 1 0 0 1 1 1 0 HAD-hyrolase-like Pkinase PF00069.20 ETS76527.1 - 1e-58 198.5 0.1 2e-58 197.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76527.1 - 1.9e-33 115.6 0.0 2.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS76527.1 - 2e-12 46.7 0.0 8.3e-11 41.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS76527.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L7Ae PF01248.21 ETS76527.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.13 ETS76528.1 - 2.9e-59 200.6 33.3 3.6e-59 200.2 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 ETS76528.1 - 3.6e-05 22.4 38.6 4.8e-05 22.0 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 ETS76529.1 - 7e-34 116.2 4.0 7e-34 116.2 2.8 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS76529.1 - 2.7e-07 30.3 0.3 8.2e-07 28.8 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like CN_hydrolase PF00795.17 ETS76530.1 - 1.7e-32 112.2 0.4 2.2e-32 111.8 0.3 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.20 ETS76531.1 - 1.4e-15 57.5 0.6 2.3e-15 56.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS76531.1 - 7.9e-06 25.6 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 ETS76531.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 ETS76532.1 - 6.7e-05 21.6 0.4 0.0011 17.6 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.16 ETS76533.1 - 1e-40 139.7 18.0 3.7e-38 131.2 12.4 2.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 ETS76533.1 - 1.2e-05 24.2 30.1 0.0032 16.2 5.8 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF21 PF01595.15 ETS76533.1 - 0.0017 17.6 3.7 0.0017 17.6 2.6 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF21 PUCC PF03209.10 ETS76533.1 - 0.0094 14.7 7.7 0.069 11.8 0.7 2.3 2 0 0 2 2 2 2 PUCC protein DUF3425 PF11905.3 ETS76534.1 - 5.1e-12 45.8 1.7 1.3e-11 44.5 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RasGAP PF00616.14 ETS76535.1 - 7.8e-54 182.3 0.1 4.1e-53 179.9 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 ETS76535.1 - 4.4e-29 101.0 5.4 4.4e-29 101.0 3.7 3.1 3 0 0 3 3 3 1 RasGAP C-terminus Syntaxin-6_N PF09177.6 ETS76535.1 - 0.17 12.2 2.7 0.36 11.2 0.7 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF972 PF06156.8 ETS76535.1 - 9.5 6.6 12.6 11 6.3 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Amidohydro_4 PF13147.1 ETS76536.1 - 5.8e-26 92.1 5.4 8.8e-23 81.7 3.7 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS76536.1 - 1.2e-16 61.2 0.1 5e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS76536.1 - 3.7e-12 45.8 2.2 1.1e-11 44.3 1.5 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS76536.1 - 5.3e-10 39.0 1.1 2.2e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.20 ETS76537.1 - 1.5e-29 102.9 0.0 2.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76537.1 - 9.1e-16 57.6 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 ETS76537.1 - 4.8e-13 49.2 0.0 4.4e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76537.1 - 1.2e-07 31.1 9.8 0.015 15.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETS76537.1 - 2.6e-06 27.4 0.3 4.5 7.6 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76537.1 - 1e-05 25.8 0.2 0.043 14.3 0.0 4.1 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76537.1 - 0.0004 20.3 0.1 3.9 8.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Kinase-like PF14531.1 ETS76537.1 - 0.0031 16.5 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like UPF0158 PF03682.8 ETS76538.1 - 3.1 7.4 6.6 2.5 7.6 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0158) Fungal_trans PF04082.13 ETS76540.1 - 3.1e-22 78.7 1.6 8.8e-22 77.2 1.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS76541.1 - 4.9e-17 61.6 2.1 5.1e-17 61.6 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 ETS76542.1 - 5.7e-32 110.8 3.1 1.7e-27 96.1 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS76542.1 - 8.5e-12 44.4 4.3 1.2e-09 37.3 1.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FUSC PF04632.7 ETS76542.1 - 0.01 14.3 0.1 0.014 13.8 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADH_N PF08240.7 ETS76543.1 - 7.6e-30 102.8 0.9 1.3e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS76543.1 - 2.7e-24 85.1 0.2 4.1e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS76543.1 - 2.7e-07 31.5 0.1 7.9e-07 30.0 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 ETS76543.1 - 0.0021 16.5 0.6 0.0029 16.1 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETS76543.1 - 0.0069 16.7 0.4 0.069 13.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 ETS76543.1 - 0.024 14.4 1.0 0.14 12.0 0.7 2.1 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DapB_N PF01113.15 ETS76543.1 - 0.096 12.6 0.3 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.13 ETS76544.1 - 4e-07 29.8 13.8 7.4e-07 28.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 ETS76545.1 - 2.7e-60 204.2 0.0 3.1e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_N PF08240.7 ETS76546.1 - 1.6e-28 98.5 0.4 3.4e-28 97.5 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS76546.1 - 9.4e-25 86.6 0.0 1.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 ETS76546.1 - 0.00021 21.2 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 ETS76546.1 - 0.00098 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 ETS76546.1 - 0.0042 16.2 5.4 0.011 14.9 3.7 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Shikimate_DH PF01488.15 ETS76546.1 - 0.013 15.5 0.1 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N_assoc PF13823.1 ETS76546.1 - 0.027 14.1 0.0 0.087 12.4 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.1 ETS76546.1 - 0.045 14.0 0.3 0.081 13.1 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS76546.1 - 0.047 13.0 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 ETS76546.1 - 0.052 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 ETS76547.1 - 7.9e-23 80.7 29.1 1.5e-17 63.4 5.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_24 PF13578.1 ETS76548.1 - 6.8e-13 49.3 0.0 1.1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ETS76548.1 - 1.4e-08 34.0 0.0 3.5e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS76548.1 - 0.015 15.9 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 ETS76548.1 - 0.077 12.2 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase CorA PF01544.13 ETS76549.1 - 3.3e-06 26.3 3.5 8e-06 25.0 2.4 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MscS_TM PF12794.2 ETS76549.1 - 0.044 12.3 0.4 0.081 11.5 0.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FA_desaturase PF00487.19 ETS76550.1 - 2.7e-26 92.5 24.6 4e-26 92.0 17.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 ETS76550.1 - 0.004 17.1 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.8 ETS76551.1 - 2e-20 73.2 0.1 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS76551.1 - 2.2e-15 56.2 0.0 3.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 ETS76553.1 - 8.3e-17 61.8 0.0 9.7e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76553.1 - 1.5e-07 31.3 0.0 1.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS76553.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 ETS76553.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase DUF336 PF03928.9 ETS76556.1 - 3.3e-24 85.1 0.3 4e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) AA_permease PF00324.16 ETS76557.1 - 2.8e-102 342.5 42.5 3.5e-102 342.2 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76557.1 - 3e-24 85.3 43.9 3.9e-24 84.9 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease OCD_Mu_crystall PF02423.10 ETS76558.1 - 2.2e-20 72.6 0.4 1.1e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 ETS76558.1 - 8.5e-08 32.3 0.0 0.00028 20.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 ETS76559.1 - 1.2e-24 86.9 0.1 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS76559.1 - 0.0048 15.8 0.1 0.0081 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 ETS76559.1 - 0.009 15.6 0.2 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 ETS76559.1 - 0.0094 15.9 0.3 0.028 14.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS76559.1 - 0.014 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 ETS76559.1 - 0.018 15.4 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 ETS76559.1 - 0.037 13.4 4.8 0.08 12.3 0.3 2.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 ETS76559.1 - 0.079 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76559.1 - 0.091 13.1 0.8 0.34 11.3 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS76559.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS76559.1 - 2.8 7.2 7.5 0.12 11.7 0.9 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.17 ETS76561.1 - 3.4e-106 355.3 0.2 4.3e-106 355.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 ETS76562.1 - 1.5e-19 69.9 0.1 2.2e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.13 ETS76563.1 - 4.9e-18 65.4 0.0 7.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 ETS76563.1 - 0.032 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Pro_dh PF01619.13 ETS76564.1 - 3.5e-32 111.6 0.0 2.6e-31 108.7 0.0 1.9 1 1 0 1 1 1 1 Proline dehydrogenase ComJ PF11033.3 ETS76564.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Competence protein J (ComJ) Aminotran_1_2 PF00155.16 ETS76565.1 - 5.5e-55 186.7 0.0 1.7e-54 185.1 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.11 ETS76566.1 - 2.3e-40 138.3 25.2 2.3e-40 138.3 17.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1932 PF09130.6 ETS76567.1 - 7.8e-17 60.7 0.1 3.9e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 ETS76567.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ETS76567.1 - 0.0089 15.4 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 ETS76567.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 ETS76568.1 - 6.8e-22 77.5 0.1 6.8e-22 77.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76568.1 - 5.7e-09 35.7 8.6 1.3e-08 34.5 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UVR PF02151.14 ETS76568.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Bac_luciferase PF00296.15 ETS76569.1 - 1.3e-55 188.7 0.6 3.3e-55 187.3 0.5 1.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 ETS76570.1 - 1.8e-08 34.1 0.0 1.7e-07 30.9 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS76570.1 - 2.8e-05 23.6 0.5 5e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 ETS76571.1 - 8.3e-31 106.9 28.9 1.2e-30 106.4 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS76571.1 - 0.0044 17.0 2.1 0.02 14.9 1.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) ESSS PF10183.4 ETS76571.1 - 0.2 12.0 0.7 1.8 8.9 0.3 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PAN_1 PF00024.21 ETS76575.1 - 5.2e-13 48.5 15.3 0.00023 20.8 0.3 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 ETS76575.1 - 6.5e-11 41.7 10.8 1.8e-05 24.3 0.2 3.8 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.7 ETS76575.1 - 4.3e-06 26.2 5.6 0.035 13.7 0.0 3.5 3 0 0 3 3 3 3 PAN-like domain MANEC PF07502.9 ETS76575.1 - 0.64 10.0 21.3 0.63 10.0 1.1 3.7 4 0 0 4 4 4 0 MANEC domain 2OG-FeII_Oxy_3 PF13640.1 ETS76577.1 - 1.3e-05 25.6 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 ETS76578.1 - 3.8e-34 116.1 29.6 4.3e-06 26.2 0.2 12.2 7 4 2 11 11 11 7 TPR repeat TPR_2 PF07719.12 ETS76578.1 - 1.7e-28 96.1 26.8 0.00029 20.5 0.2 13.8 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76578.1 - 3e-26 89.8 28.4 1.5e-05 24.3 0.1 13.6 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_12 PF13424.1 ETS76578.1 - 2.2e-22 78.7 23.9 6.7e-08 32.3 0.0 10.1 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76578.1 - 3.9e-22 76.3 26.3 8.6e-05 22.0 0.1 13.4 15 1 0 15 15 15 5 Tetratricopeptide repeat TPR_14 PF13428.1 ETS76578.1 - 1.8e-21 74.6 30.9 3e-05 24.2 0.0 14.5 15 2 2 17 17 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS76578.1 - 6.8e-21 74.3 27.4 0.00018 21.7 0.1 12.0 11 2 2 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 ETS76578.1 - 6.4e-19 68.1 30.2 0.0002 21.9 0.1 11.2 12 1 1 13 13 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS76578.1 - 1.1e-18 65.4 17.8 9.5e-05 21.9 0.0 10.3 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETS76578.1 - 2e-15 56.0 17.6 2.6e-05 24.3 0.0 10.6 11 0 0 11 11 10 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS76578.1 - 5.3e-12 45.7 13.1 0.14 12.2 0.1 8.2 6 2 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 ETS76578.1 - 1.3e-09 37.5 19.5 0.15 12.2 0.0 11.8 14 1 0 14 14 12 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS76578.1 - 0.0001 22.1 19.5 1 9.3 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat PPR PF01535.15 ETS76578.1 - 0.0085 16.0 0.7 7.8 6.7 0.0 4.6 4 0 0 4 4 2 1 PPR repeat Cellulase PF00150.13 ETS76579.1 - 1e-44 152.8 0.0 1.4e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rhomboid PF01694.17 ETS76580.1 - 1.8e-17 63.7 14.6 3.5e-17 62.7 9.9 1.5 1 1 0 1 1 1 1 Rhomboid family EHN PF06441.7 ETS76581.1 - 9.2e-31 106.0 0.0 3.2e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS76581.1 - 2.4e-11 43.9 0.4 6.1e-11 42.6 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76581.1 - 5.4e-09 35.9 0.1 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS76581.1 - 0.0066 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 ETS76582.1 - 5.6e-40 137.2 0.0 7.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4383 PF14325.1 ETS76583.1 - 0.27 11.2 7.0 0.17 11.8 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) OppC_N PF12911.2 ETS76583.1 - 3.9 6.9 11.2 0.77 9.1 0.4 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Methyltransf_23 PF13489.1 ETS76584.1 - 1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76584.1 - 3.3e-06 26.7 0.0 3.4e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76584.1 - 3.6e-05 24.1 0.0 6.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76584.1 - 0.00034 21.1 0.1 0.0079 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76584.1 - 0.0014 19.0 0.0 0.0035 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS76584.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76584.1 - 0.066 13.5 0.0 0.38 11.1 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETS76584.1 - 0.094 11.8 0.0 1.2 8.2 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Prenyltrans_2 PF13249.1 ETS76585.1 - 1.8e-06 28.3 0.1 0.023 15.0 0.0 3.9 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS76585.1 - 0.0019 18.1 0.1 1.5 8.8 0.0 3.8 4 0 0 4 4 4 1 Prenyltransferase-like Prenyltrans PF00432.16 ETS76585.1 - 0.0065 16.0 0.0 4.3 6.9 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat GST_C PF00043.20 ETS76586.1 - 5.3e-15 55.1 0.0 9.4e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS76586.1 - 2.5e-12 46.8 0.0 8.1e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS76586.1 - 5e-10 39.1 0.3 8.8e-10 38.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS76586.1 - 1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS76586.1 - 9e-09 35.2 0.0 2.5e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS76586.1 - 2e-07 31.3 0.1 3.2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 ETS76587.1 - 3.2e-39 134.6 55.7 4.8e-38 130.7 37.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 ETS76587.1 - 0.0074 15.9 0.3 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 Myc target protein 1 p450 PF00067.17 ETS76588.1 - 2.6e-25 88.8 0.0 3.1e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS76590.1 - 1.6e-28 99.4 0.0 2e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DNA_ligase_ZBD PF03119.11 ETS76592.1 - 0.09 12.4 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2470 PF10615.4 ETS76593.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) MFS_1 PF07690.11 ETS76594.1 - 4.2e-25 88.2 31.4 7.6e-21 74.2 4.2 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS76594.1 - 1.8e-11 43.2 7.9 1.8e-11 43.2 5.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 ETS76595.1 - 7.7e-48 163.1 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3392 PF11872.3 ETS76596.1 - 4.9 7.1 8.8 3.9 7.4 0.4 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) ketoacyl-synt PF00109.21 ETS76597.1 - 3.5e-61 206.9 0.0 6.8e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS76597.1 - 1.5e-53 182.2 0.0 4.5e-53 180.6 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 ETS76597.1 - 2.2e-48 164.3 2.1 2.3e-48 164.2 0.2 2.1 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 ETS76597.1 - 8.4e-43 146.6 0.1 1.6e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS76597.1 - 2.6e-38 131.5 0.1 7.7e-38 130.0 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS76597.1 - 7.1e-37 125.8 0.0 1.7e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS76597.1 - 1.5e-18 67.0 0.0 6.3e-18 65.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS76597.1 - 7.2e-18 64.3 0.1 2.3e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 ETS76597.1 - 3.2e-15 56.2 0.0 6.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS76597.1 - 2.6e-11 44.4 0.0 1.3e-10 42.2 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 ETS76597.1 - 2.1e-09 37.9 0.0 1.6e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76597.1 - 1.1e-08 35.4 0.0 2.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76597.1 - 2.2e-08 33.7 0.0 4.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 ETS76597.1 - 3.7e-08 33.5 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 ETS76597.1 - 6.7e-06 25.3 0.0 1.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 ETS76597.1 - 0.00029 20.4 0.2 0.00096 18.7 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 ETS76597.1 - 0.0019 17.8 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 ETS76597.1 - 0.0089 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 ETS76597.1 - 0.039 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF915 PF06028.6 ETS76597.1 - 0.18 10.8 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_49 PF03718.8 ETS76599.1 - 2.9e-174 580.3 24.1 3.8e-174 579.9 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Lipoprotein_15 PF03640.10 ETS76600.1 - 0.061 12.7 7.6 0.88 9.0 0.1 3.4 2 2 2 4 4 4 0 Secreted repeat of unknown function FAD-SLDH PF12318.3 ETS76600.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ank_2 PF12796.2 ETS76601.1 - 2e-55 185.0 18.9 3.3e-20 72.2 2.7 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76601.1 - 1e-47 157.6 18.3 2.4e-06 27.0 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 ETS76601.1 - 4.5e-35 116.1 10.7 0.0019 18.2 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 ETS76601.1 - 5.9e-28 96.2 12.5 6.6e-07 29.3 0.1 8.5 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76601.1 - 7.2e-28 96.4 7.3 4.7e-07 30.1 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) TPR_11 PF13414.1 ETS76601.1 - 0.079 12.6 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 TPR repeat DUF2384 PF09722.5 ETS76601.1 - 0.08 12.8 0.1 28 4.6 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) PBP PF01161.15 ETS76602.1 - 8e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dmrt1 PF12374.3 ETS76602.1 - 8.7 6.7 10.3 8.4 6.8 0.2 2.7 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Zn_clus PF00172.13 ETS76603.1 - 0.00013 21.8 10.6 0.00021 21.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 ETS76604.1 - 0.0043 16.1 0.0 0.0043 16.1 0.0 2.7 3 1 1 4 4 4 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 ETS76605.1 - 6.1e-17 61.6 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76605.1 - 1.4e-07 30.8 0.0 1.4e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_C PF05199.8 ETS76606.1 - 7.7e-23 81.3 0.1 8.7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lactonase PF10282.4 ETS76607.1 - 8.2e-85 284.9 0.1 1.1e-84 284.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1772 PF08592.6 ETS76608.1 - 4.1 7.1 11.2 1.5 8.5 1.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Ank_2 PF12796.2 ETS76610.1 - 4e-21 75.1 0.0 3.1e-08 33.8 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Clr5 PF14420.1 ETS76610.1 - 8.9e-17 60.7 0.1 2.4e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.25 ETS76610.1 - 5.4e-14 51.1 1.6 1.8e-05 24.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 ETS76610.1 - 7.4e-10 38.1 0.1 0.016 15.4 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 ETS76610.1 - 1.7e-08 34.7 0.0 0.0032 17.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76610.1 - 8.2e-05 22.7 0.1 0.4 10.9 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Chromo PF00385.19 ETS76611.1 - 0.004 16.7 0.3 0.0066 16.1 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF440 PF04269.7 ETS76612.1 - 0.023 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF440 DUF4153 PF13687.1 ETS76613.1 - 0.027 14.0 0.5 0.042 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) DJ-1_PfpI PF01965.19 ETS76614.1 - 2.9e-17 62.4 0.0 5.5e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETS76614.1 - 1.3e-05 24.6 0.0 3.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Fungal_trans PF04082.13 ETS76615.1 - 2e-22 79.3 0.7 3.1e-22 78.6 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76615.1 - 2.2e-08 33.8 11.1 3.6e-08 33.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC92 PF14916.1 ETS76615.1 - 0.00076 19.0 0.1 0.0019 17.7 0.1 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Cep57_CLD_2 PF14197.1 ETS76615.1 - 0.024 14.5 1.0 0.052 13.4 0.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Fmp27_WPPW PF10359.4 ETS76615.1 - 0.055 11.8 0.3 0.079 11.3 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 ETS76615.1 - 0.085 12.4 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 IncA protein IFP_35_N PF07334.8 ETS76615.1 - 0.11 12.5 0.3 0.3 11.0 0.2 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HR1 PF02185.11 ETS76615.1 - 0.16 11.7 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 Hr1 repeat Pox_A_type_inc PF04508.7 ETS76615.1 - 0.25 11.2 1.8 0.8 9.6 1.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.10 ETS76615.1 - 1.2 8.7 2.8 1.6 8.2 0.7 2.0 2 0 0 2 2 2 0 Septum formation initiator FAD_binding_3 PF01494.14 ETS76616.1 - 8.9e-29 100.6 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS76616.1 - 1.1e-06 27.8 0.8 0.0084 15.0 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 ETS76616.1 - 3.8e-05 22.7 0.5 0.013 14.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS76616.1 - 8.8e-05 22.4 0.2 0.00032 20.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS76616.1 - 0.0036 16.4 0.2 3.2 6.7 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS76616.1 - 0.009 15.1 0.3 0.018 14.1 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETS76616.1 - 0.012 15.4 0.2 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76616.1 - 0.021 15.2 0.3 0.14 12.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cu-oxidase_3 PF07732.10 ETS76617.1 - 2e-44 150.1 1.5 2e-44 150.1 1.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS76617.1 - 6.9e-40 135.7 9.1 2.7e-37 127.3 0.6 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS76617.1 - 2.2e-33 115.4 0.4 5.5e-33 114.1 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase COesterase PF00135.23 ETS76618.1 - 1.5e-61 208.7 0.0 5.8e-56 190.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS76618.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ABM PF03992.11 ETS76619.1 - 3.1e-05 23.9 0.1 5.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aldo_ket_red PF00248.16 ETS76620.1 - 1.3e-67 227.5 0.0 1.7e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 ETS76621.1 - 4.4e-16 59.4 0.0 9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA PF00004.24 ETS76622.1 - 4.6e-16 59.2 0.0 8.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS76622.1 - 0.0037 17.4 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS76622.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Myosin_tail_1 PF01576.14 ETS76623.1 - 8.3e-06 23.8 24.3 8.3e-06 23.8 16.9 1.5 2 0 0 2 2 2 1 Myosin tail TBPIP PF07106.8 ETS76623.1 - 0.0029 17.1 31.9 0.0041 16.6 6.8 4.2 3 1 1 4 4 4 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 ETS76623.1 - 0.038 13.8 16.7 0.24 11.2 1.2 4.3 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 ETS76623.1 - 0.062 12.7 23.4 0.05 13.1 7.7 2.6 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain TMF_DNA_bd PF12329.3 ETS76623.1 - 0.095 12.5 21.5 0.059 13.1 0.4 4.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETS76623.1 - 0.12 11.9 38.0 0.17 11.4 6.6 2.9 1 1 0 2 2 2 0 IncA protein FH2 PF02181.18 ETS76623.1 - 0.13 11.1 13.7 0.37 9.6 3.0 3.0 2 2 0 4 4 4 0 Formin Homology 2 Domain Reo_sigmaC PF04582.7 ETS76623.1 - 0.22 10.6 17.8 0.45 9.6 3.5 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ApoO PF09769.4 ETS76623.1 - 1.6 8.4 6.4 3.7 7.2 0.1 3.2 2 1 1 3 3 3 0 Apolipoprotein O HisKA_3 PF07730.8 ETS76623.1 - 1.9 8.8 16.1 7.3 7.0 0.2 4.6 5 1 0 5 5 4 0 Histidine kinase Vac_Fusion PF02346.11 ETS76623.1 - 2 7.8 12.5 0.077 12.4 1.8 3.6 4 0 0 4 4 4 0 Chordopoxvirus fusion protein DUF3584 PF12128.3 ETS76623.1 - 2.4 5.3 33.1 0.49 7.6 11.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF948 PF06103.6 ETS76623.1 - 2.7 7.8 18.1 5.4 6.9 0.2 4.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 ETS76623.1 - 6.8 5.2 29.6 13 4.3 5.9 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETS76623.1 - 9.3 6.0 19.3 7.7 6.2 0.8 3.6 2 2 2 4 4 4 0 Laminin Domain II ERG4_ERG24 PF01222.12 ETS76624.1 - 1.7e-168 560.6 1.5 1.9e-168 560.5 1.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETS76624.1 - 0.00019 20.8 0.0 0.00046 19.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 ETS76625.1 - 1.4e-08 34.1 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 ETS76625.1 - 7.2e-07 28.7 0.2 2.5e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 ETS76625.1 - 1.9e-05 24.4 0.4 0.028 14.1 0.0 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PNGaseA PF12222.3 ETS76626.1 - 3.8e-114 381.8 5.4 4.7e-114 381.5 3.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A NmrA PF05368.8 ETS76627.1 - 5.1e-22 78.2 0.0 6.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS76627.1 - 6.7e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF3394 PF11874.3 ETS76627.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3394) Transferase PF02458.10 ETS76628.1 - 5e-11 41.7 0.0 2.1e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Transferase family Histone_HNS PF00816.16 ETS76629.1 - 0.014 15.9 2.6 0.014 15.9 1.8 2.6 2 1 1 3 3 3 0 H-NS histone family Baculo_PEP_C PF04513.7 ETS76629.1 - 0.032 14.0 0.3 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tektin PF03148.9 ETS76629.1 - 0.044 12.3 11.5 0.05 12.1 7.8 1.3 1 1 0 1 1 1 0 Tektin family BRI3BP PF14965.1 ETS76629.1 - 0.061 12.6 1.8 0.14 11.5 0.3 1.9 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF1640 PF07798.6 ETS76629.1 - 0.084 12.9 4.1 0.11 12.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1509 PF07420.6 ETS76629.1 - 0.1 11.8 6.8 0.16 11.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MbeD_MobD PF04899.7 ETS76629.1 - 0.36 10.7 4.4 2.7 7.9 1.0 2.3 1 1 1 2 2 2 0 MbeD/MobD like FUSC PF04632.7 ETS76629.1 - 0.36 9.1 1.2 0.43 8.9 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.8 ETS76629.1 - 0.49 9.7 4.1 0.89 8.9 2.8 1.5 1 1 0 1 1 1 0 fzo-like conserved region UBN_AB PF14075.1 ETS76629.1 - 0.56 9.8 13.0 0.022 14.4 3.8 1.9 2 0 0 2 2 2 0 Ubinuclein conserved middle domain TMPIT PF07851.8 ETS76629.1 - 0.77 8.7 4.8 1 8.3 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein ApoO PF09769.4 ETS76629.1 - 1 9.0 5.1 3.6 7.2 3.6 1.8 1 1 0 1 1 1 0 Apolipoprotein O FlaC_arch PF05377.6 ETS76629.1 - 1.4 8.8 4.7 22 5.0 3.3 2.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.6 ETS76629.1 - 4 6.6 8.4 0.39 9.9 2.2 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein SlyX PF04102.7 ETS76629.1 - 5.3 7.5 8.3 6.1 7.3 2.4 2.7 1 1 2 3 3 3 0 SlyX CRAL_TRIO PF00650.15 ETS76630.1 - 4.8e-11 42.3 0.0 7.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS76630.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PLDc_N PF13396.1 ETS76632.1 - 1.8e-12 46.6 3.5 3.6e-12 45.7 2.4 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PTS_EIIC_2 PF13303.1 ETS76632.1 - 0.0044 15.9 0.9 0.0049 15.7 0.6 1.1 1 0 0 1 1 1 1 Phosphotransferase system, EIIC Bac_rhodopsin PF01036.13 ETS76632.1 - 0.0094 15.2 2.5 0.011 15.0 1.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MARVEL PF01284.18 ETS76632.1 - 0.025 14.4 4.6 0.032 14.0 3.2 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF4311 PF14188.1 ETS76632.1 - 0.064 12.7 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Pox_A14 PF05767.7 ETS76632.1 - 0.077 12.9 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3951 PF13131.1 ETS76632.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) RSN1_TM PF13967.1 ETS76632.1 - 0.18 11.3 1.3 0.23 11.0 0.9 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport EamA PF00892.15 ETS76632.1 - 0.19 11.7 4.6 0.22 11.5 2.7 1.5 1 1 0 1 1 1 0 EamA-like transporter family DUF3309 PF11752.3 ETS76632.1 - 0.51 10.1 6.1 0.56 10.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Chs3p PF12271.3 ETS76632.1 - 0.52 9.2 3.5 0.57 9.0 2.4 1.2 1 1 0 1 1 1 0 Chitin synthase III catalytic subunit DUF4199 PF13858.1 ETS76632.1 - 0.82 9.5 4.1 0.18 11.6 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4064 PF13273.1 ETS76632.1 - 2.9 8.0 6.6 41 4.3 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) RAMP4 PF06624.7 ETS76632.1 - 4.3 6.9 7.1 22 4.6 0.0 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Amidase PF01425.16 ETS76633.1 - 6.5e-85 285.6 0.0 8.4e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Glyco_transf_4 PF13439.1 ETS76633.1 - 0.014 15.1 0.1 0.16 11.6 0.1 2.2 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 ETS76633.1 - 0.1 12.7 0.1 2.6 8.1 0.0 2.4 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain ELH PF02323.10 ETS76633.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor HET PF06985.6 ETS76634.1 - 2.3e-30 105.5 0.4 5.6e-30 104.3 0.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS76635.1 - 1.2e-09 38.3 0.1 9.2e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76635.1 - 1.9e-06 27.4 1.4 0.0048 16.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS76635.1 - 2.3e-06 27.6 0.2 0.00034 20.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76635.1 - 0.00027 20.8 0.9 0.15 12.3 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETS76635.1 - 0.00061 20.2 0.5 0.012 16.1 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) p450 PF00067.17 ETS76636.1 - 2e-59 201.3 0.0 2.7e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Melibiase PF02065.13 ETS76637.1 - 2.1e-16 59.6 1.7 2.3e-10 39.7 0.0 2.9 2 1 0 2 2 2 2 Melibiase Alginate_lyase PF05426.7 ETS76638.1 - 0.0015 17.9 9.1 0.0061 15.9 6.3 1.8 1 1 0 1 1 1 1 Alginate lyase Imm40 PF15582.1 ETS76638.1 - 0.12 11.0 0.1 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 40 Ammonium_transp PF00909.16 ETS76639.1 - 6.2e-112 373.9 20.9 7.7e-112 373.6 14.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 ETS76639.1 - 0.034 14.0 3.4 1.4 8.8 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) NADH-u_ox-rdase PF10785.4 ETS76639.1 - 3.3 8.0 9.6 12 6.2 1.1 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Epimerase PF01370.16 ETS76641.1 - 8.2e-15 54.8 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS76641.1 - 7e-13 48.9 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS76641.1 - 5.4e-08 32.3 0.0 3.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 ETS76641.1 - 4.5e-07 28.8 0.0 0.0013 17.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS76641.1 - 1.6e-05 24.8 0.0 4.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 ETS76641.1 - 0.0019 17.1 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.15 ETS76641.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HET PF06985.6 ETS76643.1 - 4.9e-24 85.0 0.0 9.3e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Epimerase PF01370.16 ETS76644.1 - 9.1e-19 67.8 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS76644.1 - 5.9e-11 41.5 0.0 7.2e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS76644.1 - 3e-08 32.8 0.0 8.8e-08 31.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS76644.1 - 6.6e-08 32.7 0.0 8.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS76644.1 - 1.4e-07 30.6 0.0 1.3e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS76644.1 - 8.8e-07 28.9 0.0 2.4e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76644.1 - 0.00019 21.1 0.0 0.00055 19.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 ETS76644.1 - 0.022 14.5 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETS76644.1 - 0.091 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 ETS76645.1 - 2.6e-27 95.3 0.6 4.6e-27 94.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76645.1 - 3.4e-08 33.2 8.8 7.5e-08 32.1 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 ETS76646.1 - 5.4e-47 160.4 0.0 6e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family AA_permease_2 PF13520.1 ETS76648.1 - 7.3e-41 140.0 45.2 9.7e-41 139.6 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS76648.1 - 5.2e-16 58.0 39.7 6.9e-16 57.6 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.19 ETS76649.1 - 1.2e-50 172.9 0.7 1.7e-50 172.4 0.5 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS76649.1 - 1.6e-11 44.0 0.2 3.4e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS76649.1 - 1.6e-09 37.1 0.0 3.3e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 ETS76649.1 - 1.5e-06 27.5 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 ETS76649.1 - 2.6e-05 23.4 0.1 4.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS76649.1 - 0.00017 20.6 0.1 0.00027 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS76649.1 - 0.0008 19.5 0.2 0.0069 16.4 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS76649.1 - 0.0023 16.8 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 ETS76649.1 - 0.0048 15.4 0.0 0.0085 14.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS76649.1 - 0.013 14.5 0.1 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS76649.1 - 0.04 13.7 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76649.1 - 0.049 14.0 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS76649.1 - 0.097 11.5 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans_2 PF11951.3 ETS76650.1 - 4.6e-24 84.7 0.1 5.5e-14 51.5 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76650.1 - 7.8e-06 25.7 8.9 1.4e-05 24.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1320 PF07030.7 ETS76650.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) S1-P1_nuclease PF02265.11 ETS76651.1 - 2.4e-55 187.9 0.0 2.9e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Prok-RING_1 PF14446.1 ETS76651.1 - 0.0088 15.7 0.6 0.019 14.6 0.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 G-alpha PF00503.15 ETS76652.1 - 6.2e-31 107.4 0.6 1.3e-30 106.3 0.4 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS76652.1 - 3.7e-06 26.2 0.5 9.9e-06 24.8 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS76652.1 - 0.051 12.7 0.4 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.19 ETS76653.1 - 5.2e-58 196.6 27.2 6e-58 196.5 18.6 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76653.1 - 6.2e-22 77.7 34.7 9.8e-22 77.1 24.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 ETS76654.1 - 2.1e-59 201.1 0.0 2.7e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NUDE_C PF04880.8 ETS76655.1 - 1.7e-19 70.7 16.9 1.7e-19 70.7 11.7 4.1 1 1 1 2 2 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 ETS76655.1 - 0.00058 20.0 10.9 0.00058 20.0 7.5 4.0 2 1 1 4 4 4 1 Protein of unknown function (DUF904) WEMBL PF05701.6 ETS76655.1 - 0.0023 16.5 30.5 0.0032 16.0 21.2 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Chibby PF14645.1 ETS76655.1 - 0.13 12.1 13.2 0.46 10.3 1.8 2.9 1 1 1 2 2 2 0 Chibby family CCDC144C PF14915.1 ETS76655.1 - 0.64 8.8 27.2 0.48 9.3 17.1 1.8 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region IncA PF04156.9 ETS76655.1 - 1.4 8.5 35.2 0.34 10.4 11.1 2.5 2 1 1 3 3 3 0 IncA protein Filament PF00038.16 ETS76655.1 - 1.7 8.0 30.3 1.2 8.5 7.8 3.1 2 1 1 3 3 3 0 Intermediate filament protein NAD_binding_2 PF03446.10 ETS76657.1 - 5.6e-27 94.5 0.5 7.9e-27 94.0 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS76657.1 - 7.4e-09 35.7 0.1 1.7e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 ETS76657.1 - 1.4e-06 28.6 0.6 1e-05 25.8 0.0 2.5 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ETS76657.1 - 6.8e-06 26.2 0.1 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 ETS76657.1 - 0.056 12.6 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM_21 PF03370.8 ETS76658.1 - 1.1e-32 112.3 0.3 2.2e-32 111.3 0.2 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Abhydrolase_6 PF12697.2 ETS76659.1 - 1.8e-23 83.6 0.0 2.3e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76659.1 - 4.1e-09 36.3 0.1 7.1e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76659.1 - 0.00077 19.0 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold ACC_central PF08326.7 ETS76661.1 - 4e-250 831.8 0.0 5e-250 831.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 ETS76661.1 - 3.5e-175 583.0 0.0 4.9e-175 582.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 ETS76661.1 - 2.8e-51 173.8 0.0 5.2e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS76661.1 - 1.9e-24 85.9 0.1 4e-24 84.8 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS76661.1 - 3.2e-22 78.5 0.0 2.2e-20 72.6 0.0 3.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 ETS76661.1 - 1.5e-17 63.0 0.4 4.4e-17 61.4 0.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 ETS76661.1 - 6.8e-10 38.9 0.0 1.9e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS76661.1 - 9.2e-07 27.9 0.0 0.038 12.7 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 ETS76661.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 ETS76661.1 - 0.03 13.9 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp_3 PF02655.9 ETS76661.1 - 0.057 13.2 0.0 0.29 10.9 0.0 2.3 1 0 0 1 1 1 0 ATP-grasp domain BolA PF01722.13 ETS76662.1 - 3.1e-16 59.0 0.0 4.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Replicase PF03090.12 ETS76662.1 - 0.07 12.9 0.2 1.1 9.1 0.2 2.0 2 0 0 2 2 2 0 Replicase family Big_3_4 PF13754.1 ETS76663.1 - 0.045 14.0 5.4 2 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Velvet PF11754.3 ETS76663.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Velvet factor FAD-oxidase_C PF02913.14 ETS76664.1 - 1.6e-51 175.0 0.0 2.1e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS76664.1 - 9.3e-40 135.3 0.0 1.8e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 ETS76665.1 - 9e-23 81.0 1.9 2.8e-12 46.8 0.1 2.2 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETS76665.1 - 8.7e-15 55.1 0.2 2.4e-13 50.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS76665.1 - 6e-08 32.5 0.6 2.9e-06 27.0 0.1 2.2 1 1 1 2 2 2 1 KR domain Shikimate_DH PF01488.15 ETS76665.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 ETS76665.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_S8 PF00082.17 ETS76666.1 - 2.4e-47 161.4 3.2 2.1e-46 158.3 2.2 2.2 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 ETS76666.1 - 4.5e-16 59.2 0.6 1.1e-15 57.9 0.4 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 ETS76666.1 - 1.4e-10 40.7 0.2 3.6e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 ETS76666.1 - 0.00023 21.6 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 FlgD_ig PF13860.1 ETS76666.1 - 0.0012 18.5 0.0 0.0049 16.5 0.0 2.1 1 0 0 1 1 1 1 FlgD Ig-like domain SLAC1 PF03595.12 ETS76667.1 - 1.2e-83 280.5 37.8 1.4e-83 280.3 26.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel EF-hand_5 PF13202.1 ETS76667.1 - 0.14 11.5 0.2 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 EF hand VIT1 PF01988.14 ETS76669.1 - 1.6e-36 125.8 0.0 2.5e-36 125.1 0.0 1.3 1 1 0 1 1 1 1 VIT family Phosphoesterase PF04185.9 ETS76670.1 - 1.1e-33 116.9 3.2 2.8e-33 115.6 2.2 1.5 1 1 0 1 1 1 1 Phosphoesterase family Rootletin PF15035.1 ETS76675.1 - 0.005 16.8 15.8 0.005 16.8 11.0 6.8 4 3 3 7 7 7 2 Ciliary rootlet component, centrosome cohesion HTH_26 PF13443.1 ETS76675.1 - 2.2 8.5 9.6 7.4 6.8 0.0 4.9 5 0 0 5 5 5 0 Cro/C1-type HTH DNA-binding domain POT1 PF02765.12 ETS76676.1 - 2.6e-13 50.1 0.0 4.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Ribosomal_L34 PF00468.12 ETS76677.1 - 1.9e-10 40.2 15.1 3.5e-10 39.4 10.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L34 Ish1 PF10281.4 ETS76678.1 - 0.0017 18.3 0.1 0.0033 17.4 0.0 1.5 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 ETS76678.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 SAP domain tRNA-synt_1g PF09334.6 ETS76679.1 - 8.5e-109 363.7 0.1 1.4e-108 363.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETS76679.1 - 2.3e-18 65.5 2.9 1.4e-11 43.1 0.0 4.1 1 1 2 4 4 4 4 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.1 ETS76679.1 - 7.2e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 ETS76679.1 - 9.3e-05 21.6 0.0 0.0046 16.1 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 ETS76679.1 - 0.00011 21.9 0.0 0.00033 20.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Acetyltransf_8 PF13523.1 ETS76679.1 - 0.012 15.4 0.0 1.2 8.9 0.0 2.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS76679.1 - 0.021 14.5 0.0 0.56 10.0 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein CorA PF01544.13 ETS76680.1 - 5e-11 42.1 0.1 1.8e-10 40.3 0.0 1.9 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF4334 PF14232.1 ETS76680.1 - 0.016 14.8 0.1 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) GHMP_kinases_N PF00288.21 ETS76681.1 - 3.4e-19 68.6 0.2 1.4e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS76681.1 - 3.8e-07 30.2 0.0 8.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PPTA PF01239.17 ETS76682.1 - 3.9e-41 136.7 4.7 3.4e-08 32.4 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 ETS76682.1 - 0.22 11.4 1.6 0.56 10.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.18 ETS76683.1 - 1.5e-63 214.4 0.3 2.6e-63 213.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS76683.1 - 1.5e-12 47.2 0.0 4.4e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 ETS76683.1 - 4.7e-06 26.1 13.7 4.7e-06 26.1 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 ETS76683.1 - 8.6e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 ETS76683.1 - 0.00017 21.3 12.4 0.00017 21.3 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS76683.1 - 0.00024 20.7 11.5 0.00024 20.7 8.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS76683.1 - 0.00076 19.4 12.5 0.00076 19.4 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 ETS76683.1 - 0.0071 15.1 0.0 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 TIR_2 PF13676.1 ETS76683.1 - 0.12 12.5 0.1 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 TIR domain zf-Nse PF11789.3 ETS76683.1 - 0.43 10.1 9.6 0.23 11.0 4.4 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LRR_6 PF13516.1 ETS76684.1 - 8e-08 31.5 1.6 0.00092 19.0 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.1 ETS76684.1 - 3.1e-05 23.6 5.7 0.058 13.1 0.3 5.1 3 2 1 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 ETS76684.1 - 0.00037 20.0 3.0 0.0032 17.0 0.5 3.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) CDC27 PF09507.5 ETS76684.1 - 0.0094 15.2 12.5 0.014 14.6 8.6 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 GATA PF00320.22 ETS76684.1 - 0.03 13.6 0.2 0.066 12.5 0.1 1.5 1 0 0 1 1 1 0 GATA zinc finger Hanta_nucleocap PF00846.13 ETS76684.1 - 0.035 12.8 0.0 0.066 11.8 0.0 1.4 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein LRR_1 PF00560.28 ETS76684.1 - 0.095 12.7 0.5 19 5.8 0.1 4.6 6 1 0 6 6 6 0 Leucine Rich Repeat BAF1_ABF1 PF04684.8 ETS76684.1 - 0.43 9.3 10.2 0.66 8.7 7.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LRR_7 PF13504.1 ETS76684.1 - 0.87 10.0 4.5 45 4.8 0.0 5.6 8 1 0 8 8 8 0 Leucine rich repeat Ribosomal_60s PF00428.14 ETS76684.1 - 1.6 9.2 23.5 0.15 12.4 12.8 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein adh_short PF00106.20 ETS76685.1 - 3.1e-22 79.2 1.8 9.7e-22 77.6 1.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS76685.1 - 7.9e-13 48.7 0.0 9.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS76685.1 - 2.1e-06 27.8 0.4 4.8e-06 26.6 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS76685.1 - 3.3e-06 26.8 1.2 5.8e-06 26.0 0.6 1.6 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 ETS76685.1 - 3.8e-05 22.9 0.0 0.033 13.3 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 ETS76685.1 - 0.00039 19.9 0.1 0.00079 18.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS76685.1 - 0.005 15.7 0.1 0.0084 15.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 ETS76685.1 - 0.021 14.0 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 ETS76685.1 - 0.03 14.3 0.1 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.21 ETS76685.1 - 0.034 13.6 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 ETS76685.1 - 0.036 14.4 0.1 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EHN PF06441.7 ETS76686.1 - 3.6e-17 62.3 0.6 6.4e-17 61.4 0.4 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus TaqI_C PF12950.2 ETS76686.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Pkinase PF00069.20 ETS76687.1 - 8.8e-08 31.6 0.0 5.7e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76687.1 - 1.4e-05 24.3 0.5 0.0026 16.8 0.3 3.5 1 1 0 1 1 1 1 Protein tyrosine kinase CAP_N PF01213.14 ETS76687.1 - 1.4 8.1 9.4 0.046 13.0 1.6 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 ETS76688.1 - 6.6e-06 25.4 0.0 0.00065 18.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76688.1 - 0.16 11.0 0.0 4.1 6.3 0.0 2.7 2 1 0 2 2 2 0 Protein tyrosine kinase NTF2 PF02136.15 ETS76689.1 - 3.6e-05 24.1 0.3 7.2e-05 23.1 0.2 1.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PALP PF00291.20 ETS76690.1 - 9.7e-60 202.3 0.2 1.2e-59 202.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hid1 PF12722.2 ETS76691.1 - 3.4e-260 865.5 0.0 1.6e-259 863.3 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 ETS76691.1 - 2.1e-83 280.6 0.0 3.2e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Daxx PF03344.10 ETS76691.1 - 0.43 8.9 4.7 0.7 8.3 3.3 1.2 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 ETS76692.1 - 1.9e-19 69.5 79.9 1.8e-14 53.2 31.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS76692.1 - 0.0056 16.6 14.9 0.027 14.5 0.7 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF1228) PfkB PF00294.19 ETS76693.1 - 4.2e-16 58.9 0.0 8.2e-16 57.9 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase cNMP_binding PF00027.24 ETS76693.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Saccharop_dh PF03435.13 ETS76694.1 - 6.9e-134 446.6 0.0 7.8e-134 446.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETS76694.1 - 1.2e-05 25.3 0.2 5.1e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 ETS76694.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 ETS76694.1 - 0.055 12.8 0.2 0.89 8.9 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ETS76694.1 - 0.073 13.5 0.1 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Las1 PF04031.8 ETS76695.1 - 9.6e-59 197.4 0.1 1.3e-58 197.0 0.1 1.2 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 ETS76696.1 - 3.5e-26 92.0 2.8 1.2e-25 90.2 1.9 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS76696.1 - 1.8e-05 24.4 0.1 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.1 ETS76696.1 - 0.036 13.4 0.5 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain LVIVD PF08309.6 ETS76696.1 - 0.098 11.6 0.5 0.24 10.4 0.3 1.6 1 0 0 1 1 1 0 LVIVD repeat DUF1236 PF06823.7 ETS76696.1 - 0.11 12.2 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Cation_efflux PF01545.16 ETS76698.1 - 6.2e-34 117.3 3.5 8.5e-34 116.9 2.4 1.1 1 0 0 1 1 1 1 Cation efflux family zf-MYND PF01753.13 ETS76699.1 - 2e-07 30.7 19.6 2e-07 30.7 13.6 2.0 2 0 0 2 2 2 1 MYND finger IF4E PF01652.13 ETS76700.1 - 1.1e-35 122.6 0.6 1.3e-35 122.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TRAPP PF04051.11 ETS76700.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component EF-hand_7 PF13499.1 ETS76701.1 - 0.0092 16.1 0.0 0.064 13.3 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS76701.1 - 0.082 12.8 0.0 13 5.9 0.0 4.0 5 1 0 5 5 5 0 EF-hand domain EF-hand_9 PF14658.1 ETS76701.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain DEAD PF00270.24 ETS76702.1 - 7.5e-47 158.9 0.0 1.7e-45 154.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS76702.1 - 2.5e-28 97.7 0.1 7.2e-28 96.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS76702.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 ETS76702.1 - 0.037 13.1 0.1 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 ETS76702.1 - 0.081 11.3 0.0 0.19 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Proteasome PF00227.21 ETS76703.1 - 4.5e-30 104.3 0.0 5.1e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 ETS76704.1 - 8.4e-28 95.2 9.9 2.8e-07 30.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 ETS76704.1 - 0.016 13.3 0.1 0.65 8.0 0.1 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Ras PF00071.17 ETS76705.1 - 6.7e-45 152.3 0.1 7.6e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS76705.1 - 1.1e-14 54.9 0.1 1.4e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 ETS76705.1 - 3e-06 26.8 0.0 2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 ETS76705.1 - 3.1e-06 26.5 0.0 3.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS76705.1 - 9.5e-06 25.5 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS76705.1 - 0.002 17.3 0.0 0.0051 16.0 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 ETS76705.1 - 0.0093 15.8 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 ETS76705.1 - 0.031 13.5 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.20 ETS76706.1 - 3.1e-36 124.5 0.0 5.6e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 ETS76706.1 - 6.6e-17 61.4 6.1 6.6e-17 61.4 4.3 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Peptidase_C78 PF07910.8 ETS76707.1 - 2.6e-66 222.8 0.0 3.9e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 ETS76707.1 - 0.003 17.6 5.1 0.3 11.2 0.4 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding PRP21_like_P PF12230.3 ETS76707.1 - 0.0043 16.5 0.1 0.013 15.0 0.0 1.8 1 1 1 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_4 PF13894.1 ETS76707.1 - 0.021 15.1 1.2 0.021 15.1 0.9 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_C47 PF05543.8 ETS76707.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Staphopain peptidase C47 Peptidase_C39_2 PF13529.1 ETS76707.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family Ham1p_like PF01725.11 ETS76708.1 - 1.7e-26 92.7 0.0 1.9e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 ETS76709.1 - 2.9e-20 72.4 0.0 3.2e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 ETS76710.1 - 4.3e-28 98.2 0.6 1.3e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS76710.1 - 3.1e-15 57.0 1.8 8.2e-15 55.7 0.1 1.9 1 1 0 2 2 2 1 AAA domain SKI PF01202.17 ETS76710.1 - 3.8e-05 23.6 0.1 0.00011 22.1 0.1 1.7 1 1 0 1 1 1 1 Shikimate kinase ADK PF00406.17 ETS76710.1 - 4e-05 23.5 0.0 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 ETS76710.1 - 4.4e-05 23.3 0.1 0.0085 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS76710.1 - 5.8e-05 23.1 0.6 0.0001 22.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS76710.1 - 0.00034 20.8 0.0 0.00096 19.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 ETS76710.1 - 0.002 17.8 0.2 0.0045 16.7 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.1 ETS76710.1 - 0.0047 17.0 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 ETS76710.1 - 0.0094 15.3 0.1 0.73 9.1 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.1 ETS76710.1 - 0.016 15.0 0.0 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 ETS76710.1 - 0.016 14.4 0.0 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 ETS76710.1 - 0.019 14.7 0.1 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ETS76710.1 - 0.028 14.3 0.0 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 ETS76710.1 - 0.05 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 ETS76710.1 - 0.068 13.0 0.1 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family DUF3322 PF11795.3 ETS76710.1 - 0.071 12.7 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) RuvB_N PF05496.7 ETS76710.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 ETS76710.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 ETS76710.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 ETS76710.1 - 0.1 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 ETS76710.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 ETS76710.1 - 0.16 10.6 0.3 0.29 9.8 0.1 1.5 1 1 0 1 1 1 0 ArgK protein Myosin_head PF00063.16 ETS76711.1 - 1.2e-245 816.8 0.2 1.2e-245 816.8 0.1 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 ETS76711.1 - 1e-34 118.5 3.2 2.9e-34 117.0 2.2 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 ETS76711.1 - 1.3e-10 39.9 33.8 3.9e-06 26.0 1.3 7.0 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_22 PF13401.1 ETS76711.1 - 0.00085 19.4 0.0 0.0038 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 ETS76711.1 - 0.0016 17.7 2.1 0.0032 16.7 1.5 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein T2SE PF00437.15 ETS76711.1 - 0.0086 15.0 0.0 0.022 13.6 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 ETS76711.1 - 0.017 14.8 0.0 0.056 13.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 ETS76711.1 - 0.026 14.6 0.0 1.7 8.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.7 ETS76711.1 - 0.033 14.0 10.6 0.22 11.3 6.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.1 ETS76711.1 - 0.042 13.8 0.3 0.46 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Myosin_N PF02736.14 ETS76711.1 - 0.053 13.1 0.9 0.13 11.9 0.6 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain CENP-Q PF13094.1 ETS76711.1 - 0.095 12.7 18.6 0.32 10.9 12.9 1.9 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 ETS76711.1 - 0.25 10.5 25.1 16 4.6 17.4 2.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 ETS76711.1 - 0.61 10.1 23.0 0.087 12.8 7.5 3.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 ETS76711.1 - 0.66 8.9 24.3 0.27 10.2 12.1 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 ETS76711.1 - 0.78 9.6 24.9 25 4.7 8.8 2.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 2-Hacid_dh_C PF02826.14 ETS76712.1 - 8.8e-51 171.5 0.0 1.4e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS76712.1 - 5.3e-35 119.7 0.0 7.1e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS76712.1 - 0.00014 21.7 0.1 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 ETS76712.1 - 0.0063 15.9 0.1 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 ETS76712.1 - 0.0073 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 ETS76712.1 - 0.021 14.1 0.1 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAP PF00956.13 ETS76713.1 - 4.7e-88 294.4 10.2 4.7e-88 294.4 7.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 ETS76713.1 - 0.14 12.0 16.5 0.099 12.5 4.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit P5-ATPase PF12409.3 ETS76714.1 - 4.9e-39 132.8 0.1 8.1e-38 128.9 0.0 2.6 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 ETS76714.1 - 1.6e-30 106.6 0.0 3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETS76714.1 - 4.8e-28 97.7 0.0 9.3e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS76714.1 - 4.2e-17 63.2 0.0 2.3e-15 57.5 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS76714.1 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 ETS76714.1 - 0.029 14.3 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS76714.1 - 0.18 11.3 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WAPL PF07814.8 ETS76715.1 - 1.8e-10 40.1 0.5 2.9e-09 36.1 0.0 2.5 2 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 ETS76716.1 - 6.5e-81 270.4 0.0 8.9e-81 270.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 ETS76716.1 - 0.00024 20.8 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 ETS76716.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 ETS76717.1 - 1.9e-27 94.7 0.2 2.7e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SCA7 PF08313.7 ETS76717.1 - 0.12 11.9 0.5 0.23 11.0 0.3 1.5 1 0 0 1 1 1 0 SCA7, zinc-binding domain GTP_CH_N PF12471.3 ETS76718.1 - 5.9e-92 306.6 0.0 8.7e-92 306.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 ETS76718.1 - 6.6e-17 61.2 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4614 PF15391.1 ETS76719.1 - 0.77 9.4 5.0 0.9 9.2 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ribosomal_S3Ae PF01015.13 ETS76720.1 - 1.8e-82 275.4 3.3 2.2e-82 275.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 ETS76720.1 - 0.063 13.6 1.1 0.11 12.8 0.0 2.0 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain Ras PF00071.17 ETS76721.1 - 1.6e-48 164.1 0.0 1.9e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS76721.1 - 1.8e-17 63.9 0.0 2.4e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS76721.1 - 1.2e-12 47.4 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS76721.1 - 4.6e-06 25.9 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS76721.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS76721.1 - 0.00013 21.4 0.0 0.00057 19.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 ETS76721.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ETS76721.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 ETS76721.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 ETS76721.1 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS76721.1 - 0.0038 17.3 0.0 0.007 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS76721.1 - 0.0047 17.2 0.0 0.0059 16.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETS76721.1 - 0.0069 15.8 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 ETS76721.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 ETS76721.1 - 0.02 14.0 0.0 0.088 11.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS76721.1 - 0.023 15.4 0.2 0.04 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS76721.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 ETS76721.1 - 0.047 13.2 0.1 0.077 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 ETS76721.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin Zeta_toxin PF06414.7 ETS76721.1 - 0.12 11.4 0.1 0.48 9.5 0.1 1.9 1 1 0 1 1 1 0 Zeta toxin cobW PF02492.14 ETS76721.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 ETS76721.1 - 0.14 11.7 0.0 8 5.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.2 ETS76722.1 - 5.3e-32 111.5 0.0 8.2e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS76722.1 - 2.2e-16 60.1 0.3 1.3e-15 57.5 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS76722.1 - 1.5e-14 54.0 0.0 3.9e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS76722.1 - 2.4e-06 27.3 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 ETS76722.1 - 0.0001 22.5 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 ETS76722.1 - 0.0015 18.3 0.3 0.0025 17.6 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 ETS76722.1 - 0.047 13.2 0.1 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 ETS76722.1 - 0.066 12.6 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Zn_clus PF00172.13 ETS76723.1 - 0.0082 16.0 11.2 0.018 14.9 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS76724.1 - 3.1e-41 141.2 50.7 3.1e-41 141.2 35.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS76724.1 - 4.3e-14 51.6 23.2 7e-14 50.9 16.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.6 ETS76725.1 - 4.5e-22 78.7 0.7 1.4e-21 77.1 0.5 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS76726.1 - 6.6e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS76726.1 - 2.6e-05 24.2 0.0 0.0003 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain PGAP1 PF07819.8 ETS76726.1 - 5.5e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 ETS76726.1 - 0.00011 22.3 0.0 0.00045 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 ETS76726.1 - 0.0042 16.3 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_10 PF12846.2 ETS76726.1 - 0.012 15.1 0.1 0.05 13.0 0.0 2.1 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.24 ETS76726.1 - 0.021 15.0 0.0 0.083 13.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.2 ETS76726.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_29 PF13555.1 ETS76726.1 - 0.027 13.9 0.0 0.085 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS76726.1 - 0.029 15.1 0.0 0.089 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain LCAT PF02450.10 ETS76726.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 ETS76726.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MMR_HSR1 PF01926.18 ETS76726.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 ETS76726.1 - 0.081 13.2 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS76726.1 - 0.091 12.4 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 ETS76726.1 - 0.095 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETS76726.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 ETS76726.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 ETS76726.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain tRNA-synt_2 PF00152.15 ETS76727.1 - 1.6e-70 237.5 0.0 2.8e-70 236.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS76727.1 - 2.4e-07 30.5 0.0 4.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 ETS76727.1 - 0.11 12.3 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain KfrA_N PF11740.3 ETS76727.1 - 0.12 12.8 7.1 0.31 11.4 5.0 1.7 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RRM_6 PF14259.1 ETS76728.1 - 2.5e-41 139.4 0.1 6.6e-12 45.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS76728.1 - 2.2e-36 123.2 0.1 2.4e-11 43.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS76728.1 - 8.8e-21 73.5 0.1 6.7e-06 25.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 ETS76728.1 - 6.9e-10 38.3 2.5 6.9e-10 38.3 1.7 3.8 3 0 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 ETS76728.1 - 0.00024 20.9 0.1 0.057 13.2 0.1 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 ETS76728.1 - 0.006 16.3 0.0 4.5 7.1 0.0 3.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 ETS76728.1 - 0.0066 16.4 0.0 0.045 13.7 0.0 2.4 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.1 ETS76728.1 - 0.17 11.4 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) His_Phos_2 PF00328.17 ETS76729.1 - 3.1e-23 82.6 0.0 5.6e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.1 ETS76730.1 - 6.7e-26 90.0 0.1 1.8e-07 31.0 0.0 7.1 5 2 2 7 7 7 5 PPR repeat family PPR_3 PF13812.1 ETS76730.1 - 1.9e-16 58.8 5.4 0.21 11.9 0.0 10.2 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 ETS76730.1 - 6.4e-13 47.7 0.3 0.16 11.9 0.0 7.1 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 ETS76730.1 - 4.4e-05 22.8 0.9 5.1 6.6 0.0 5.6 6 0 0 6 6 6 1 PPR repeat TPR_19 PF14559.1 ETS76730.1 - 0.00047 20.4 1.3 0.5 10.7 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat SPOB_a PF14689.1 ETS76730.1 - 0.079 12.5 0.0 34 4.1 0.0 3.9 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain SMP PF04927.7 ETS76731.1 - 0.00022 21.0 11.8 0.056 13.4 0.2 3.8 3 2 1 4 4 4 3 Seed maturation protein Abhydrolase_1 PF00561.15 ETS76732.1 - 0.047 13.2 0.6 0.076 12.5 0.2 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Equine_IAV_S2 PF06502.6 ETS76732.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Abhydrolase_3 PF07859.8 ETS76732.1 - 0.073 12.6 0.4 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FA_hydroxylase PF04116.8 ETS76734.1 - 4.1e-17 62.6 10.4 4.1e-17 62.6 7.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 ETS76735.1 - 2.1e-54 183.9 1.1 2.6e-54 183.6 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.13 ETS76735.1 - 0.014 15.7 1.0 0.042 14.2 0.6 1.8 1 1 1 2 2 2 0 Ribosomal protein S20 PSII_Pbs27 PF13326.1 ETS76735.1 - 0.077 12.9 0.2 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Photosystem II Pbs27 ParB PF08775.5 ETS76735.1 - 0.13 12.5 0.5 0.19 12.0 0.3 1.2 1 0 0 1 1 1 0 ParB family Mis12 PF05859.7 ETS76737.1 - 4e-39 133.6 0.0 7.1e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DUF4570 PF15134.1 ETS76737.1 - 0.44 10.4 3.5 4.3 7.2 0.9 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4570) DUF1059 PF06348.6 ETS76739.1 - 0.098 12.4 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Laminin_I PF06008.9 ETS76739.1 - 0.66 9.2 3.9 0.47 9.7 0.5 2.0 2 0 0 2 2 2 0 Laminin Domain I PhyH PF05721.8 ETS76741.1 - 1.2e-20 74.4 0.0 1.7e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 ETS76741.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase SCP2 PF02036.12 ETS76741.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF1479 PF07350.7 ETS76741.1 - 0.093 11.2 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) HTH_Tnp_4 PF13613.1 ETS76741.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease GMC_oxred_N PF00732.14 ETS76742.1 - 8.6e-57 192.5 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS76742.1 - 1e-35 123.1 0.0 2.5e-35 121.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS76742.1 - 3.8e-06 26.0 0.4 6.4e-06 25.3 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS76742.1 - 9.5e-05 22.3 0.2 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS76742.1 - 0.00048 19.1 0.1 0.00079 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS76742.1 - 0.0014 17.6 0.1 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS76742.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS76742.1 - 0.17 10.2 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein COX5A PF02284.11 ETS76742.1 - 0.18 11.7 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DNA_ligase_A_M PF01068.16 ETS76746.1 - 2.9e-58 196.5 1.1 4.2e-56 189.5 0.8 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETS76746.1 - 6.5e-53 179.1 0.6 1.2e-52 178.3 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETS76746.1 - 4.8e-28 97.3 0.0 2.4e-27 95.1 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region MaoC_dehydrat_N PF13452.1 ETS76747.1 - 0.012 15.3 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase Pkinase PF00069.20 ETS76748.1 - 2e-69 233.6 0.0 3.1e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76748.1 - 3.8e-50 170.3 0.0 6.5e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 ETS76748.1 - 6.9e-30 103.0 0.0 1.5e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 ETS76748.1 - 6.6e-16 57.9 0.1 1.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETS76748.1 - 1.7e-15 56.9 0.1 3.2e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 ETS76748.1 - 8.5e-14 51.8 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 ETS76748.1 - 9.2e-07 28.0 0.0 0.00037 19.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 ETS76748.1 - 0.022 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Seadorna_VP7 PF07387.6 ETS76748.1 - 0.19 10.5 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_4 PF12799.2 ETS76749.1 - 0.0032 17.0 7.7 0.59 9.8 0.0 6.5 6 3 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 ETS76749.1 - 0.017 15.1 13.0 8.8 6.7 0.1 7.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 ETS76749.1 - 0.29 11.5 10.1 15 6.3 0.1 6.4 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 ETS76749.1 - 3.5 8.0 15.1 48 4.5 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich Repeat Pkinase PF00069.20 ETS76750.1 - 0.0011 18.2 0.0 0.034 13.2 0.0 2.2 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS76750.1 - 0.0054 15.8 0.0 0.57 9.2 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Flexi_CP PF00286.15 ETS76750.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Viral coat protein FA_desaturase PF00487.19 ETS76751.1 - 0.026 13.9 0.2 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF4231 PF14015.1 ETS76751.1 - 0.042 13.8 0.5 0.08 12.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Claudin_2 PF13903.1 ETS76751.1 - 0.056 13.1 0.7 0.078 12.6 0.4 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ceramidase PF05875.7 ETS76752.1 - 8e-58 195.6 0.1 9.5e-58 195.3 0.1 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 ETS76752.1 - 0.27 10.9 2.6 1 9.1 1.8 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide DUF3474 PF11960.3 ETS76753.1 - 0.17 11.9 0.8 0.34 10.9 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) SET PF00856.23 ETS76754.1 - 3e-10 40.6 0.0 6.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 SET domain SAF PF08666.7 ETS76754.1 - 0.04 14.2 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 SAF domain HET PF06985.6 ETS76755.1 - 1.4e-20 73.8 0.0 3.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS76756.1 - 9.6e-18 64.6 12.1 9.6e-18 64.6 8.4 4.2 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF342 PF03961.8 ETS76756.1 - 0.53 8.6 5.7 0.94 7.8 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ank_2 PF12796.2 ETS76757.1 - 6.7e-62 205.8 22.9 3.5e-12 46.4 0.2 7.4 2 1 6 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76757.1 - 1e-45 151.2 22.0 6.4e-06 25.7 0.0 13.9 13 1 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 ETS76757.1 - 4.5e-45 151.2 20.4 4.9e-07 30.1 0.0 10.7 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76757.1 - 1.2e-39 133.4 19.0 4e-06 26.8 0.0 10.0 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76757.1 - 3.6e-37 122.6 17.5 0.00026 20.9 0.0 13.6 13 1 1 14 14 14 9 Ankyrin repeat CorA PF01544.13 ETS76757.1 - 2.1e-08 33.5 0.3 8.7e-08 31.5 0.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 ETS76758.1 - 7.4e-17 61.7 0.0 1.7e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS76758.1 - 0.00025 21.0 1.0 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 ETS76758.1 - 0.00027 20.6 0.1 0.00067 19.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS76758.1 - 0.00033 20.7 0.3 0.0061 16.6 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS76758.1 - 0.00033 20.3 0.0 0.00078 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETS76758.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS76758.1 - 0.026 14.0 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETS76758.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS76758.1 - 0.035 14.3 0.3 0.4 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 ETS76758.1 - 0.044 12.9 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 ETS76758.1 - 0.049 13.1 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 ETS76758.1 - 0.054 13.0 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vfa1 PF08432.5 ETS76758.1 - 0.51 10.3 5.1 1.2 9.1 3.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_17 PF13207.1 ETS76758.1 - 1.4 9.7 12.8 0.82 10.5 2.2 4.3 3 3 0 3 3 3 0 AAA domain UBA PF00627.26 ETS76759.1 - 2.4e-07 30.4 0.1 3.7e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 ETS76759.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain SNAP PF14938.1 ETS76760.1 - 0.059 12.5 0.3 0.19 10.8 0.1 1.8 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP H-kinase_dim PF02895.9 ETS76760.1 - 0.13 12.5 0.5 0.56 10.5 0.0 2.2 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Gag_spuma PF03276.9 ETS76761.1 - 0.23 9.7 1.3 0.23 9.7 0.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Fungal_trans_2 PF11951.3 ETS76762.1 - 0.00017 20.3 0.0 0.00032 19.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS76763.1 - 1e-18 67.7 0.2 1.7e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76763.1 - 1.3e-13 50.9 0.1 2.3e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS76763.1 - 0.0055 16.1 0.1 0.0093 15.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS76763.1 - 0.0062 15.4 0.1 0.013 14.4 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein COesterase PF00135.23 ETS76764.1 - 3.9e-79 266.7 0.0 6.3e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS76764.1 - 5.3e-10 39.2 0.1 2.9e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS76764.1 - 0.0014 18.4 0.1 0.0022 17.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS76764.1 - 0.1 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 ETS76765.1 - 1.1e-42 146.1 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Neurochondrin PF05536.6 ETS76766.1 - 1.1e-72 245.1 2.7 1.4e-72 244.7 1.8 1.1 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 ETS76766.1 - 0.087 12.4 2.5 1.3 8.6 0.0 3.5 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis Voltage_CLC PF00654.15 ETS76767.1 - 2.6e-91 306.3 28.8 2.6e-91 306.3 20.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 ETS76767.1 - 1.2e-07 31.3 0.0 0.0094 15.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain zf-C3HC4_3 PF13920.1 ETS76768.1 - 2.9e-10 39.6 9.1 4.1e-10 39.1 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS76768.1 - 3.2e-09 36.4 12.2 4.9e-09 35.8 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS76768.1 - 1.5e-07 31.3 11.0 2.3e-07 30.7 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS76768.1 - 8.5e-07 28.6 11.1 1.3e-06 28.0 7.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS76768.1 - 3.5e-06 26.5 11.6 5.3e-06 25.9 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS76768.1 - 0.00015 21.5 5.0 0.00025 20.8 3.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETS76768.1 - 0.0019 17.8 3.5 0.0019 17.8 2.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 ETS76768.1 - 0.0043 16.6 5.8 0.0082 15.7 4.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 ETS76768.1 - 0.033 14.3 4.5 0.055 13.5 3.1 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETS76768.1 - 0.034 14.0 8.7 0.059 13.2 6.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY-C PF15616.1 ETS76768.1 - 0.044 13.7 2.6 0.077 12.9 1.8 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.1 ETS76768.1 - 0.079 12.7 3.4 0.16 11.8 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 ETS76768.1 - 0.16 11.4 8.2 0.85 9.2 5.7 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 ETS76768.1 - 8.2 6.0 9.9 15 5.1 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Methyltransf_18 PF12847.2 ETS76770.1 - 3.2e-13 50.2 0.0 6.6e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76770.1 - 2.9e-07 30.3 0.0 5e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS76770.1 - 8.2e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 ETS76770.1 - 2.9e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76770.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76770.1 - 0.0021 18.5 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 ETS76770.1 - 0.0024 18.6 0.7 0.0077 17.0 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS76770.1 - 0.0051 15.9 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS76770.1 - 0.0059 17.0 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS76770.1 - 0.0077 15.3 0.0 0.042 12.9 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 ETS76770.1 - 0.0079 16.2 0.7 0.017 15.1 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETS76770.1 - 0.025 13.9 0.0 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 ETS76770.1 - 0.088 12.2 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 ETS76770.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Imm28 PF15574.1 ETS76770.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 28 Fibrillarin PF01269.12 ETS76770.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DNA_pol_A PF00476.15 ETS76771.1 - 5.6e-98 328.0 0.0 7.6e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A Methyltransf_2 PF00891.13 ETS76773.1 - 1.6e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 ETS76773.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76773.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76773.1 - 0.025 15.1 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76773.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 ETS76776.1 - 2.2e-20 73.0 0.0 8.1e-20 71.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS76776.1 - 5.2e-06 26.4 1.0 1.2e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS76776.1 - 7.3e-05 21.8 0.2 0.00052 19.0 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS76776.1 - 8e-05 22.9 0.2 0.00017 21.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS76776.1 - 0.00044 20.3 0.0 0.0031 17.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS76776.1 - 0.0026 16.6 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase FAD_binding_2 PF00890.19 ETS76776.1 - 0.02 13.7 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS76776.1 - 0.021 14.7 0.6 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS76776.1 - 0.025 13.6 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS76776.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 ETS76776.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS76776.1 - 0.12 10.8 0.3 0.32 9.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pab87_oct PF13969.1 ETS76776.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Pab87 octamerisation domain HET PF06985.6 ETS76777.1 - 4.3e-33 114.4 3.2 7e-33 113.7 2.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.16 ETS76779.1 - 3.4e-127 424.7 32.6 3.8e-127 424.5 22.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76779.1 - 1.1e-46 159.2 39.5 1.4e-46 158.9 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3414 PF11894.3 ETS76780.1 - 0 1312.6 0.0 0 1312.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 ETS76781.1 - 2.4e-44 151.5 0.0 4.7e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 ETS76781.1 - 2.1e-30 105.4 0.2 2.1e-30 105.4 0.1 4.8 5 1 0 5 5 5 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 ETS76781.1 - 1.4e-11 43.6 0.0 3.2e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain SICA_alpha PF12887.2 ETS76781.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 SICA extracellular alpha domain Arginase PF00491.16 ETS76783.1 - 8.6e-89 297.5 0.0 1e-88 297.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 ETS76783.1 - 0.16 12.1 1.3 0.34 11.0 0.3 1.8 1 1 0 2 2 2 0 UPF0489 domain Ras PF00071.17 ETS76784.1 - 9.7e-53 177.8 0.0 1.3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS76784.1 - 4.2e-16 59.5 0.0 8.5e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS76784.1 - 4.2e-07 29.3 0.0 5.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.26 ETS76786.1 - 1.2e-22 79.4 0.2 3.1e-22 78.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-CCHC PF00098.18 ETS76786.1 - 2.8e-09 36.4 22.5 3.1e-06 26.8 0.7 3.6 3 0 0 3 3 3 2 Zinc knuckle RRM_1 PF00076.17 ETS76786.1 - 0.019 14.6 0.0 0.093 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 ETS76786.1 - 0.024 14.3 7.2 0.75 9.5 0.6 2.9 1 1 1 2 2 2 0 Zinc knuckle SAPS PF04499.10 ETS76786.1 - 0.88 8.1 4.3 1.1 7.8 3.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4448 PF14610.1 ETS76787.1 - 3.8e-25 88.4 0.0 5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 ETS76787.1 - 0.052 12.8 0.4 0.099 11.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.16 ETS76787.1 - 0.13 12.1 2.4 0.27 11.0 1.7 1.5 1 0 0 1 1 1 0 Gram positive anchor GPI-anchored PF10342.4 ETS76787.1 - 0.24 11.9 2.0 0.47 10.9 1.4 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HAD_2 PF13419.1 ETS76788.1 - 2.8e-24 86.2 0.3 5.1e-24 85.4 0.2 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS76788.1 - 9.3e-07 29.4 0.0 1.5e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS76788.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Bac_luciferase PF00296.15 ETS76789.1 - 1.4e-58 198.5 0.7 1.8e-58 198.0 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 ETS76790.1 - 8.1e-23 80.7 32.3 1.4e-22 79.9 22.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family RINGv PF12906.2 ETS76792.1 - 9e-17 60.8 9.1 1.5e-16 60.1 6.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 ETS76792.1 - 0.073 12.9 8.2 0.13 12.0 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 ETS76792.1 - 0.15 11.9 2.3 0.31 10.8 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETS76792.1 - 0.49 10.5 3.1 1.1 9.3 2.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 ETS76792.1 - 5.3 6.7 6.6 9.1 5.9 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Apolipoprotein PF01442.13 ETS76794.1 - 0.084 12.3 17.7 3.2e+02 0.6 10.3 4.3 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.11 ETS76795.1 - 4.7e-31 107.7 21.3 4.7e-31 107.7 14.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 ETS76796.1 - 1.6e-49 168.6 0.0 2.6e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS76797.1 - 5.3e-56 190.0 0.0 1e-55 189.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2633 PF11119.3 ETS76797.1 - 0.089 12.5 0.4 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) tRNA-synt_1d PF00750.14 ETS76798.1 - 2.5e-81 273.2 5.5 1e-80 271.2 3.8 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 ETS76798.1 - 1.9e-26 92.3 0.2 5.2e-26 90.9 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Acyl-CoA_dh_N PF02771.11 ETS76798.1 - 0.05 14.1 0.2 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain DUF2430 PF10353.4 ETS76798.1 - 0.13 12.4 0.2 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Ferric_reduct PF01794.14 ETS76799.1 - 3.4e-16 59.4 14.1 3.4e-16 59.4 9.8 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS76799.1 - 2.9e-15 56.0 0.1 8.8e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS76799.1 - 3.4e-12 46.5 0.1 5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain COesterase PF00135.23 ETS76801.1 - 4.8e-96 322.6 0.0 6.2e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS76801.1 - 0.00053 19.6 0.2 0.0032 17.0 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.18 ETS76802.1 - 7.5e-29 99.9 1.4 1.3e-28 99.2 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS76802.1 - 5.3e-11 42.2 0.0 9.7e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TPP_enzyme_N PF02776.13 ETS76803.1 - 3.2e-40 137.4 0.1 9.1e-40 135.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS76803.1 - 9.1e-22 77.2 0.0 2.8e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 ETS76803.1 - 1e-20 73.8 0.0 1e-20 73.8 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Nbs1_C PF08599.5 ETS76803.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 HpcH_HpaI PF03328.9 ETS76804.1 - 2.5e-35 121.3 0.0 3.6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 ETS76804.1 - 0.13 10.8 1.1 0.3 9.6 0.6 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain adh_short PF00106.20 ETS76805.1 - 3.2e-20 72.7 0.8 6.2e-19 68.5 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76805.1 - 3.4e-12 46.4 0.0 2.2e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS76805.1 - 2.5e-11 43.7 0.3 1.7e-08 34.5 0.2 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 ETS76805.1 - 0.0051 16.4 0.4 0.011 15.3 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS76805.1 - 0.021 14.9 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 ETS76805.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family AA_kinase PF00696.23 ETS76805.1 - 0.043 13.3 0.1 0.59 9.6 0.1 2.3 2 1 0 2 2 2 0 Amino acid kinase family F420_oxidored PF03807.12 ETS76805.1 - 0.048 14.0 0.5 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 ETS76805.1 - 0.056 13.0 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SKI PF01202.17 ETS76805.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NAD_binding_10 PF13460.1 ETS76805.1 - 0.11 12.4 0.4 1.1 9.2 0.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 ETS76805.1 - 0.12 12.1 5.1 0.48 10.2 0.6 2.2 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 ETS76805.1 - 0.14 11.5 0.2 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 ETS76806.1 - 1.1e-72 245.0 20.9 1.4e-72 244.7 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76806.1 - 3e-26 91.9 45.9 5e-24 84.6 17.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily AfaD PF05775.7 ETS76806.1 - 0.04 13.8 0.2 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein DUF4149 PF13664.1 ETS76806.1 - 0.17 11.9 0.2 0.17 11.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) PhyH PF05721.8 ETS76807.1 - 7.6e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS76807.1 - 0.027 12.9 0.1 0.34 9.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) DUF3934 PF13070.1 ETS76807.1 - 0.12 12.5 0.8 5.6 7.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3934) ADH_zinc_N PF00107.21 ETS76808.1 - 2.5e-12 46.4 0.0 1.2e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS76808.1 - 3.2e-05 24.8 0.0 0.00011 23.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 ETS76808.1 - 0.0052 16.1 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 ETS76808.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS76808.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 ETS76809.1 - 5.9e-08 32.4 0.3 8.2e-08 31.9 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.13 ETS76811.1 - 0.00011 21.2 0.3 0.00024 20.0 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain LAT PF15234.1 ETS76811.1 - 0.027 13.9 1.5 0.054 12.9 1.0 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells FMN_dh PF01070.13 ETS76812.1 - 3.2e-116 388.0 0.0 4.4e-116 387.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS76812.1 - 3.5e-08 32.7 0.1 8.4e-08 31.5 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS76812.1 - 8e-06 24.9 4.9 4.3e-05 22.5 0.9 3.0 2 2 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 ETS76812.1 - 0.00018 20.8 0.8 0.12 11.6 0.0 2.8 2 1 0 2 2 2 2 Histidine biosynthesis protein NMO PF03060.10 ETS76812.1 - 0.0011 18.2 1.3 0.016 14.3 1.0 2.1 1 1 1 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.16 ETS76812.1 - 0.0023 16.9 0.3 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.12 ETS76812.1 - 0.0038 16.1 0.1 0.045 12.5 0.0 2.4 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 ETS76812.1 - 0.0041 16.2 0.1 1.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Cyclin PF08613.6 ETS76813.1 - 2.6e-39 135.0 0.0 4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Peptidase_M24 PF00557.19 ETS76814.1 - 3.4e-56 190.0 0.0 4.4e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETS76814.1 - 1.6e-25 89.0 0.0 3.6e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DAO PF01266.19 ETS76815.1 - 5.7e-53 180.0 0.4 1.4e-52 178.7 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS76815.1 - 5.4e-07 29.9 0.0 0.037 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS76815.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS76815.1 - 0.0004 20.3 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS76815.1 - 0.0033 17.2 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS76815.1 - 0.0034 16.0 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 ETS76815.1 - 0.019 14.0 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 ETS76815.1 - 0.022 13.8 1.2 0.037 13.1 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_S10 PF00450.17 ETS76816.1 - 5.8e-83 279.3 1.2 8.1e-83 278.8 0.9 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 ETS76817.1 - 5e-39 133.9 22.1 5e-39 133.9 15.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MCR_alpha PF02249.12 ETS76817.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF1597 PF07642.6 ETS76817.1 - 0.097 11.6 0.2 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 Outer membrane protein family (DUF1597) DUF4231 PF14015.1 ETS76817.1 - 0.25 11.3 5.8 0.35 10.8 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) OTT_1508_deam PF14441.1 ETS76819.1 - 0.0027 17.4 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase ADH_N PF08240.7 ETS76820.1 - 1.3e-22 79.6 0.2 2.4e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS76820.1 - 4e-17 61.9 0.0 6.5e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS76820.1 - 0.00011 21.3 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS76820.1 - 0.0042 16.6 0.1 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 ETS76820.1 - 0.026 14.1 0.1 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 ETS76820.1 - 0.064 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HeLo PF14479.1 ETS76821.1 - 2.8e-09 37.0 0.3 2e-05 24.4 0.1 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation Kdo PF06293.9 ETS76821.1 - 0.033 13.2 0.0 0.081 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 ETS76821.1 - 2.9 5.6 7.3 4.8 4.9 5.1 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_28 PF00295.12 ETS76822.1 - 1.7e-33 116.0 7.2 2.3e-33 115.5 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Minor_capsid_1 PF10665.4 ETS76822.1 - 0.024 14.4 0.0 1.9 8.3 0.0 2.8 2 1 1 3 3 3 0 Minor capsid protein Epimerase PF01370.16 ETS76823.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1768 PF08719.6 ETS76824.1 - 5.5e-20 71.6 3.6 3.7e-14 52.7 0.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) YL1 PF05764.8 ETS76824.1 - 0.11 12.1 12.3 0.17 11.4 5.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.9 ETS76824.1 - 4.5 5.1 8.1 6.5 4.6 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cu-oxidase_2 PF07731.9 ETS76826.1 - 3e-38 130.4 1.5 3e-38 130.4 1.1 2.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS76826.1 - 4.1e-36 123.2 1.8 4.1e-36 123.2 1.3 3.1 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS76826.1 - 4.5e-35 120.8 0.3 1.7e-34 119.0 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_N PF00732.14 ETS76828.1 - 5.3e-68 229.3 0.0 5e-67 226.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS76828.1 - 1.8e-29 102.8 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS76828.1 - 6.6e-08 31.8 0.4 6.4e-07 28.6 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS76828.1 - 7e-05 21.8 1.3 0.0033 16.3 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS76828.1 - 0.00022 20.2 0.7 0.00045 19.2 0.5 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS76828.1 - 0.00055 19.9 0.4 0.0017 18.3 0.2 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS76828.1 - 0.0022 18.1 1.1 2.9 7.8 0.9 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS76828.1 - 0.062 13.1 0.3 1.1 9.1 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS76828.1 - 0.071 11.5 0.3 0.12 10.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 ETS76828.1 - 0.16 12.3 0.7 1.4 9.3 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transp_cyt_pur PF02133.10 ETS76829.1 - 9.2e-21 73.8 36.4 1.7e-20 72.9 25.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PAP2_3 PF14378.1 ETS76830.1 - 1.8e-19 69.9 14.9 2.1e-10 40.4 0.4 3.8 2 1 1 3 3 3 3 PAP2 superfamily DUF485 PF04341.7 ETS76831.1 - 0.052 13.2 5.4 0.15 11.7 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF3366 PF11846.3 ETS76831.1 - 1.5 8.6 4.9 18 5.1 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) PgaD PF13994.1 ETS76831.1 - 4.1 6.8 6.4 0.46 9.9 0.4 2.2 2 1 0 2 2 2 0 PgaD-like protein PsiB PF06290.6 ETS76832.1 - 0.027 13.8 0.3 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Plasmid SOS inhibition protein (PsiB) DUF1220 PF06758.8 ETS76832.1 - 0.53 10.1 9.6 5.7 6.8 0.1 3.9 1 1 2 4 4 4 0 Repeat of unknown function (DUF1220) Neur_chan_memb PF02932.11 ETS76832.1 - 2.9 7.7 5.2 9.1 6.0 3.6 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pmp3 PF01679.12 ETS76834.1 - 1.5e-20 72.5 8.1 2e-20 72.2 5.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.13 ETS76835.1 - 2.2e-18 65.0 13.3 7.3e-11 40.9 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 ETS76835.1 - 1.1e-08 34.6 0.0 2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 ETS76835.1 - 3.3e-07 30.7 0.0 5.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 ETS76835.1 - 9.5e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 ETS76835.1 - 4.4 7.2 11.0 0.75 9.6 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 ETS76837.1 - 1.2e-41 139.0 3.1 1.4e-08 34.2 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 ETS76837.1 - 9.4e-29 99.1 0.1 2.7e-28 97.6 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 ETS76837.1 - 7.7e-05 22.1 0.0 0.0039 16.6 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4059 PF13268.1 ETS76837.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) XRN_N PF03159.13 ETS76838.1 - 1.6e-103 345.1 0.0 2.7e-103 344.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Dioxygenase_C PF00775.16 ETS76839.1 - 6e-10 38.6 0.2 1.4e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase DIOX_N PF14226.1 ETS76840.1 - 9.6e-15 55.1 0.0 1.7e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS76840.1 - 1.6e-12 47.5 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS76841.1 - 3.4e-08 32.5 6.0 4.5e-08 32.2 4.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESPR PF13018.1 ETS76841.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system MFS_1 PF07690.11 ETS76842.1 - 6e-22 77.8 17.9 6.2e-21 74.4 11.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 ETS76842.1 - 0.0038 16.6 1.4 0.056 12.9 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Ribonucleas_3_3 PF14622.1 ETS76844.1 - 9.8e-23 80.5 0.0 3.2e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like DUF3411 PF11891.3 ETS76844.1 - 0.016 14.8 0.2 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3411) WD-3 PF09765.4 ETS76844.1 - 0.084 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 WD-repeat region KAT11 PF08214.6 ETS76845.1 - 1.4e-84 284.1 0.0 2.5e-84 283.3 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein 2-Hacid_dh_C PF02826.14 ETS76846.1 - 1e-38 132.2 0.0 1.3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS76846.1 - 4e-11 42.5 0.0 5.3e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS76846.1 - 1.7e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS76846.1 - 0.00028 21.2 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 ETS76846.1 - 0.0083 16.6 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 ETS76846.1 - 0.037 14.4 0.1 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Ank_2 PF12796.2 ETS76847.1 - 8.6e-30 102.9 0.0 5.8e-14 52.2 0.0 4.3 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76847.1 - 5.1e-22 76.5 0.7 2.1e-07 30.3 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 ETS76847.1 - 9.7e-19 66.9 0.8 9.8e-06 25.6 0.0 7.7 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76847.1 - 2.3e-18 66.1 0.6 0.0006 20.2 0.0 5.9 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76847.1 - 7e-17 59.8 0.1 0.0038 17.3 0.0 8.5 10 0 0 10 10 10 3 Ankyrin repeat HpcH_HpaI PF03328.9 ETS76848.1 - 3.2e-24 85.0 0.0 4.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Calsarcin PF05556.6 ETS76849.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Zn_clus PF00172.13 ETS76850.1 - 6.7e-17 61.1 20.3 4.7e-09 36.0 5.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS76850.1 - 1.6e-07 30.4 0.3 2.5e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.17 ETS76851.1 - 9.1e-28 97.1 0.3 1.5e-27 96.5 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS76851.1 - 8.5e-07 28.7 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 ETS76851.1 - 0.00053 20.3 0.2 0.0013 19.0 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETS76851.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_3 PF03447.11 ETS76851.1 - 0.042 14.2 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 ETS76851.1 - 0.046 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain TrkA_N PF02254.13 ETS76851.1 - 0.055 13.4 0.1 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AA_permease PF00324.16 ETS76852.1 - 3.2e-103 345.6 39.2 3.8e-103 345.3 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76852.1 - 3.9e-28 98.1 42.1 4.5e-28 97.9 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 ETS76852.1 - 0.02 14.4 2.2 0.25 10.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DPM3 PF08285.6 ETS76852.1 - 10 6.0 8.0 1.5 8.7 1.1 2.9 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) COesterase PF00135.23 ETS76853.1 - 2.3e-78 264.2 0.0 3.3e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS76853.1 - 7.7e-13 48.4 0.2 1.3e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS76853.1 - 0.05 12.8 0.4 0.087 12.0 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mito_carr PF00153.22 ETS76854.1 - 4.1e-21 74.4 3.2 4.8e-08 32.6 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein ESSS PF10183.4 ETS76854.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PSDC PF12588.3 ETS76856.1 - 9.8e-49 164.5 0.0 1.4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 ETS76856.1 - 6.5e-35 120.2 0.0 1.6e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.17 ETS76856.1 - 0.095 12.3 0.1 0.5 10.0 0.1 2.1 2 0 0 2 2 2 0 Biotin-requiring enzyme Glyco_hydro_6 PF01341.12 ETS76857.1 - 2e-107 359.0 4.2 3.1e-107 358.4 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 ETS76857.1 - 8.2e-11 41.3 11.8 2.3e-10 39.9 8.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain MSP1_C PF07462.6 ETS76857.1 - 7.9 4.7 9.9 12 4.1 6.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Adap_comp_sub PF00928.16 ETS76858.1 - 3.3e-86 288.6 0.0 4.2e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS76858.1 - 2.2e-05 24.1 0.1 4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 ETS76858.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) HD PF01966.17 ETS76859.1 - 3.7e-05 23.7 0.0 7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HD domain FAD_binding_4 PF01565.18 ETS76860.1 - 1.7e-25 89.1 2.0 2.9e-25 88.3 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS76860.1 - 6.3e-10 38.7 0.3 1.4e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Aldolase_II PF00596.16 ETS76861.1 - 1.1e-43 148.9 0.4 1.5e-43 148.5 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glyco_hydro_61 PF03443.9 ETS76862.1 - 4.9e-69 232.4 0.4 5.8e-69 232.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fasciclin PF02469.17 ETS76863.1 - 6.7e-48 161.9 5.1 7.5e-24 84.1 0.9 2.1 2 0 0 2 2 2 2 Fasciclin domain Pyridox_oxidase PF01243.15 ETS76864.1 - 1.6e-11 44.0 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AA_permease PF00324.16 ETS76865.1 - 9.3e-97 324.3 37.1 1.2e-96 324.0 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76865.1 - 1e-23 83.5 39.6 1.3e-23 83.2 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease DCP1 PF06058.8 ETS76866.1 - 5.3e-13 49.0 0.0 7.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 ETS76867.1 - 1.1e-15 58.3 0.2 3.7e-15 56.5 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ammonium_transp PF00909.16 ETS76868.1 - 2.8e-120 401.4 28.6 3.1e-120 401.2 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Corona_NS2 PF04753.7 ETS76868.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 OPT PF03169.10 ETS76869.1 - 2.5e-97 326.8 38.5 2.9e-97 326.6 26.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GFA PF04828.9 ETS76871.1 - 2.9e-09 36.7 3.7 1.3e-06 28.2 0.0 3.5 4 1 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 ETS76871.1 - 1.2 8.8 9.6 3.7 7.3 0.5 3.7 3 0 0 3 3 3 0 Nudix N-terminal Transp_cyt_pur PF02133.10 ETS76872.1 - 6.6e-98 328.1 35.1 7.6e-98 327.9 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 ETS76873.1 - 1.2e-27 96.7 0.1 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS76873.1 - 5.3e-20 71.5 0.0 8.1e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipase_GDSL PF00657.17 ETS76875.1 - 2.8e-07 30.5 0.1 4.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS76875.1 - 3.3e-06 27.3 0.4 6.4e-06 26.4 0.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 ETS76875.1 - 0.036 13.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Cyclin_N PF00134.18 ETS76876.1 - 0.003 17.1 0.1 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain p450 PF00067.17 ETS76877.1 - 8.9e-72 242.0 0.0 1e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 ETS76878.1 - 1.4e-07 31.1 0.1 3.3e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS76878.1 - 0.00024 20.6 0.0 0.00067 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 ETS76878.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Mannosyl_trans3 PF11051.3 ETS76879.1 - 2.8e-71 240.0 0.0 1.1e-70 238.1 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative CFEM PF05730.6 ETS76880.1 - 6.1e-11 41.9 12.6 1.5e-10 40.6 8.7 1.7 1 0 0 1 1 1 1 CFEM domain DUF89 PF01937.14 ETS76881.1 - 3.7e-135 450.3 0.0 4.2e-135 450.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Formyl_trans_N PF00551.14 ETS76882.1 - 1.6e-35 122.3 0.1 2.6e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 ETS76882.1 - 1.7e-10 40.1 0.0 4.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 ETS76882.1 - 1.7e-05 24.4 0.0 5.6e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 ACT domain Glyco_trans_4_2 PF13477.1 ETS76882.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_hydro_72 PF03198.9 ETS76883.1 - 4.1e-123 410.3 5.7 5.4e-123 409.9 4.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 ETS76883.1 - 4.9e-20 71.8 5.0 2.1e-19 69.8 3.5 2.1 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 ETS76883.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain CFC PF09443.5 ETS76883.1 - 0.3 10.7 1.2 0.84 9.3 0.1 2.0 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Pex14_N PF04695.8 ETS76884.1 - 0.37 10.8 6.4 0.46 10.5 4.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 ETS76884.1 - 1.2 8.7 10.5 1.6 8.3 7.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 ETS76884.1 - 1.8 6.7 4.6 1.8 6.7 3.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 ETS76884.1 - 4.3 6.2 6.5 5.3 5.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ORC6 PF05460.8 ETS76884.1 - 8.2 5.4 7.0 10 5.1 4.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AcetylCoA_hydro PF02550.10 ETS76885.1 - 0.042 13.6 0.1 0.046 13.4 0.1 1.1 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain TPR_11 PF13414.1 ETS76886.1 - 6.2e-13 48.2 1.7 1e-07 31.5 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETS76886.1 - 2e-09 36.6 5.6 3.8e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS76886.1 - 1.4e-06 27.6 1.8 0.015 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS76886.1 - 2.2e-05 24.3 4.2 0.00067 19.5 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS76886.1 - 2.2e-05 24.9 2.9 0.00018 22.1 0.9 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS76886.1 - 0.00013 22.2 0.2 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS76886.1 - 0.00025 21.4 3.7 0.00041 20.7 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 ETS76886.1 - 0.00086 19.0 0.0 0.083 12.7 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS76886.1 - 0.0011 19.3 0.6 0.19 12.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS76886.1 - 0.0085 15.9 3.7 0.054 13.3 0.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS76886.1 - 0.019 14.7 0.6 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS76886.1 - 0.037 14.1 0.2 1.1 9.4 0.0 2.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 ETS76886.1 - 0.18 12.3 0.7 0.18 12.3 0.5 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TauD PF02668.11 ETS76887.1 - 8.7e-26 91.1 0.0 1.2e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS76887.1 - 0.0022 16.9 0.1 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 CsiD Acyltransferase PF01553.16 ETS76889.1 - 3.5e-25 87.9 0.0 5e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2305 PF10230.4 ETS76890.1 - 8.4e-59 199.1 0.0 9.7e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 ETS76890.1 - 2.5e-07 30.8 0.3 3.1e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76890.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS76890.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.17 ETS76891.1 - 6.9e-25 87.8 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS76891.1 - 3e-14 52.7 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 ETS76891.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 ETS76891.1 - 0.026 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_kinase PF01513.16 ETS76892.1 - 1.1e-45 155.6 0.0 2.2e-45 154.6 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase Dynamin_N PF00350.18 ETS76893.1 - 1.1e-29 103.3 0.1 2.7e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS76893.1 - 3.9e-15 55.4 0.1 3.8e-11 42.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 ETS76893.1 - 6.3e-06 26.1 0.0 2.6e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS76893.1 - 0.00049 20.5 0.0 0.0023 18.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein DUF4512 PF14975.1 ETS76894.1 - 0.28 12.0 1.6 0.54 11.1 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) FA_hydroxylase PF04116.8 ETS76895.1 - 4.8e-15 55.9 25.5 5.5e-15 55.7 15.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SnoaL_4 PF13577.1 ETS76898.1 - 4.8e-11 42.6 0.0 5.5e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 ETS76899.1 - 3.5e-37 127.9 25.3 4.5e-37 127.5 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2243 PF10002.4 ETS76899.1 - 0.015 15.0 1.5 0.024 14.3 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) SpoVAB PF13782.1 ETS76899.1 - 0.031 14.2 1.4 0.082 12.9 0.9 1.8 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF1932 PF09130.6 ETS76900.1 - 5.3e-14 51.7 0.0 1.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 ETS76900.1 - 2.7e-08 33.8 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS76900.1 - 1.5e-06 28.5 0.0 2.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ETS76900.1 - 0.00055 19.6 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.12 ETS76900.1 - 0.0017 17.2 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.14 ETS76900.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 ETS76900.1 - 0.005 16.2 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Fe-ADH PF00465.14 ETS76901.1 - 1.3e-69 234.6 0.0 1.6e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS76901.1 - 4.3e-10 39.3 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TraH_2 PF06871.6 ETS76901.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 TraH_2 Amino_oxidase PF01593.19 ETS76902.1 - 2.2e-62 211.6 0.1 3.7e-62 210.8 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 ETS76902.1 - 1.1e-15 57.4 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 ETS76902.1 - 4e-13 49.1 0.1 1e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS76902.1 - 4.1e-09 35.8 0.6 5.4e-07 28.8 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS76902.1 - 4.7e-09 35.6 0.6 7.2e-09 34.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS76902.1 - 7.5e-07 28.4 0.3 1.4e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS76902.1 - 5.4e-06 26.6 0.8 3.7e-05 23.8 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS76902.1 - 3.7e-05 23.6 0.3 0.00028 20.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS76902.1 - 4.4e-05 22.7 0.2 7.1e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS76902.1 - 7.5e-05 21.3 0.4 0.00013 20.5 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS76902.1 - 8.6e-05 21.6 0.3 0.0011 18.0 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 ETS76902.1 - 0.00016 20.9 0.7 0.00023 20.3 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS76902.1 - 0.0014 17.6 0.4 0.0031 16.4 0.3 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS76902.1 - 0.024 15.0 0.4 0.095 13.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS76902.1 - 0.041 13.6 0.4 2 8.1 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 ETS76902.1 - 0.066 12.7 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 ETS76903.1 - 1.4e-21 77.0 0.0 1.8e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS76903.1 - 4.2e-16 58.4 0.0 7.8e-16 57.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS76903.1 - 2.3e-12 47.2 0.1 4.6e-12 46.3 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS76903.1 - 1.4e-10 40.4 0.0 6.2e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS76903.1 - 1.1e-06 28.6 0.2 1.9e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76903.1 - 1.4e-05 24.8 0.1 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS76903.1 - 2.1e-05 23.5 0.1 3.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 ETS76903.1 - 0.0012 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 ETS76903.1 - 0.0043 16.3 0.1 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 ETS76903.1 - 0.0094 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 ETS76903.1 - 0.038 12.9 0.1 0.067 12.1 0.1 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase AA_permease PF00324.16 ETS76904.1 - 1.2e-100 337.1 45.2 1.5e-100 336.8 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS76904.1 - 1.5e-25 89.6 49.5 1.8e-25 89.4 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease ApbA PF02558.11 ETS76905.1 - 8.4e-27 93.4 0.1 1.1e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 ETS76905.1 - 2.9e-25 88.6 0.0 4.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Shikimate_DH PF01488.15 ETS76905.1 - 0.016 15.2 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 ETS76905.1 - 0.046 13.5 0.9 0.12 12.2 0.6 1.7 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 ETS76905.1 - 0.11 11.4 0.2 0.2 10.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Fungal_trans_2 PF11951.3 ETS76906.1 - 2.7e-47 161.1 1.6 3.6e-47 160.8 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.16 ETS76907.1 - 9.2e-47 159.0 0.1 1.1e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FMN_dh PF01070.13 ETS76908.1 - 1.2e-115 386.1 0.0 1.9e-115 385.5 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS76908.1 - 6e-06 25.3 0.5 1.2e-05 24.3 0.3 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS76908.1 - 8e-05 21.7 0.2 0.00015 20.7 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 ETS76908.1 - 0.00066 19.0 0.2 0.059 12.6 0.0 2.7 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.9 ETS76908.1 - 0.0066 15.5 0.6 0.25 10.4 0.0 2.9 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 ETS76908.1 - 0.017 14.0 0.1 0.042 12.8 0.0 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 ETS76908.1 - 0.023 13.8 1.2 0.041 13.0 0.4 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase DUF702 PF05142.7 ETS76908.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Ank_2 PF12796.2 ETS76909.1 - 5.2e-98 321.5 3.1 1.7e-19 69.9 0.1 7.3 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76909.1 - 5.6e-86 278.3 6.4 1.8e-07 30.6 0.0 15.9 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.1 ETS76909.1 - 8.7e-66 217.2 7.3 8e-10 38.9 0.0 10.5 4 3 8 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76909.1 - 8.9e-65 208.1 0.7 3e-06 26.9 0.0 14.4 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.1 ETS76909.1 - 2.1e-54 180.3 6.4 1.6e-08 34.4 0.1 11.4 5 5 7 12 12 12 9 Ankyrin repeats (many copies) GST_C PF00043.20 ETS76910.1 - 4.1e-09 36.3 0.0 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS76910.1 - 8.5e-09 35.1 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS76910.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS76910.1 - 1.1e-06 29.0 0.0 8.3e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS76910.1 - 2.5e-06 27.4 0.0 7.3e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS76910.1 - 3.3e-06 27.1 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TEP1_N PF05386.6 ETS76910.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain 3Beta_HSD PF01073.14 ETS76911.1 - 7.6e-48 162.6 0.0 1e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS76911.1 - 5.5e-22 78.3 0.0 7.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS76911.1 - 6.4e-13 48.2 0.1 3.2e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 ETS76911.1 - 1.1e-11 44.2 0.1 5.1e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS76911.1 - 1.4e-10 41.4 0.0 2.5e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS76911.1 - 3.3e-07 29.4 0.7 2.6e-06 26.5 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS76911.1 - 0.0001 22.3 0.1 0.00036 20.5 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76911.1 - 0.00019 21.1 0.1 0.001 18.7 0.1 2.1 1 1 0 1 1 1 1 KR domain Kinesin PF00225.18 ETS76912.1 - 8.1e-94 314.0 0.7 1.9e-93 312.8 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain Fib_alpha PF08702.5 ETS76912.1 - 0.043 13.9 18.3 0.087 12.9 2.0 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Acyltransferase PF01553.16 ETS76913.1 - 0.021 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.16 ETS76914.1 - 4.8e-208 691.7 1.2 5.6e-208 691.5 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.13 ETS76916.1 - 7.9e-06 24.9 1.4 1.4e-05 24.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 ETS76917.1 - 1.2e-83 279.4 63.4 9.9e-46 155.5 15.7 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 ETS76917.1 - 1.2e-34 119.5 0.0 1.3e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS76917.1 - 1.5e-34 117.7 9.9 3.3e-33 113.4 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 ETS76917.1 - 5.7e-18 64.7 0.1 1.3e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 ETS76917.1 - 1.4e-09 37.4 38.1 2.4e-06 26.8 8.6 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 ETS76917.1 - 7.4e-08 32.3 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS76917.1 - 4.3e-06 26.0 0.0 0.00037 19.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS76917.1 - 6.6e-06 26.9 0.0 0.039 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS76917.1 - 1.1e-05 24.9 0.0 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS76917.1 - 7.4e-05 22.2 0.8 0.043 13.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 ETS76917.1 - 8.8e-05 21.8 0.0 0.038 13.2 0.0 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS76917.1 - 0.00021 21.3 0.2 0.14 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETS76917.1 - 0.00082 19.6 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETS76917.1 - 0.0016 18.4 0.3 0.25 11.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain cobW PF02492.14 ETS76917.1 - 0.0033 16.9 0.2 0.032 13.6 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 ETS76917.1 - 0.0051 16.5 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 ETS76917.1 - 0.0071 16.4 0.1 1.7 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 ETS76917.1 - 0.0074 15.8 0.1 0.37 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RUN PF02759.14 ETS76917.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 RUN domain NACHT PF05729.7 ETS76917.1 - 0.026 14.1 0.4 2.3 7.8 0.1 3.0 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 ETS76917.1 - 0.046 13.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Serglycin PF04360.7 ETS76917.1 - 0.063 13.0 0.6 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 Serglycin AAA PF00004.24 ETS76917.1 - 0.082 13.1 0.0 23 5.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETS76917.1 - 0.16 11.9 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 ETS76917.1 - 0.28 11.4 0.0 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS76917.1 - 0.54 9.9 2.3 4.5 6.9 0.1 2.9 4 0 0 4 4 3 0 Uncharacterised P-loop hydrolase UPF0079 F-box-like PF12937.2 ETS76918.1 - 7.9e-06 25.5 0.0 2.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 ETS76918.1 - 0.012 15.2 1.6 1.1 8.9 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Amidohydro_1 PF01979.15 ETS76919.1 - 1.9e-31 109.9 1.9 2.4e-31 109.6 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS76919.1 - 2.7e-16 60.4 5.6 1.3e-13 51.6 3.9 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS76919.1 - 2.3e-06 27.1 9.0 6.9e-06 25.5 2.2 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS76919.1 - 3.5e-06 26.7 0.8 6.8e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase OPT PF03169.10 ETS76920.1 - 1.7e-134 449.6 61.5 1.9e-134 449.4 42.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.17 ETS76921.1 - 3.2e-76 257.1 0.0 4.7e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 ETS76921.1 - 0.0011 18.7 0.0 0.0067 16.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS76921.1 - 0.005 16.7 0.0 0.047 13.5 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_MA_2 PF13485.1 ETS76922.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 ETS76922.1 - 7.8e-05 22.6 1.3 0.00031 20.7 0.0 2.2 1 1 1 2 2 2 1 M61 glycyl aminopeptidase PDZ PF00595.19 ETS76922.1 - 0.00016 21.7 0.0 0.00053 20.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) RE_TdeIII PF09520.5 ETS76922.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Peptidase_S10 PF00450.17 ETS76923.1 - 9.1e-96 321.5 0.0 1.1e-95 321.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS76923.1 - 0.0001 22.2 0.0 0.0024 17.7 0.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS76923.1 - 0.0039 16.9 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.22 ETS76924.1 - 4.4e-45 153.3 0.0 4e-28 98.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS76924.1 - 1.5e-24 86.9 26.2 1.8e-13 50.5 3.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS76924.1 - 1e-09 37.9 6.2 0.00047 19.4 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS76924.1 - 7.3e-07 29.4 0.9 0.06 13.2 0.1 3.9 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 ETS76924.1 - 1.1e-06 28.7 3.2 0.028 14.3 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS76924.1 - 3.7e-06 27.1 1.2 0.036 14.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS76924.1 - 0.00021 20.7 5.7 0.035 13.6 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS76924.1 - 0.0003 20.2 3.5 0.3 10.4 0.3 2.8 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS76924.1 - 0.00089 18.2 1.4 0.21 10.4 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 ETS76924.1 - 0.0011 17.7 0.0 0.012 14.2 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_19 PF13245.1 ETS76924.1 - 0.0066 16.1 0.9 0.37 10.5 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS76924.1 - 0.008 15.7 0.8 14 5.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS76924.1 - 0.0081 15.6 0.2 0.64 9.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS76924.1 - 0.011 16.0 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETS76924.1 - 0.012 15.2 1.2 3 7.5 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 ETS76924.1 - 0.037 12.9 0.1 0.2 10.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 ETS76924.1 - 0.053 13.0 4.3 1.8 8.0 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 ETS76924.1 - 0.058 12.5 0.7 0.84 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 ETS76924.1 - 0.11 11.6 1.1 2.1 7.4 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 ETS76924.1 - 0.11 12.1 3.5 8.5 6.0 0.1 3.2 3 0 0 3 3 3 0 NTPase Miro PF08477.8 ETS76924.1 - 0.17 12.3 2.8 0.25 11.8 0.1 2.6 3 0 0 3 3 2 0 Miro-like protein RNA_helicase PF00910.17 ETS76924.1 - 0.17 12.0 0.8 9.4 6.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_17 PF13207.1 ETS76924.1 - 0.19 12.5 10.0 12 6.7 2.0 3.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS76924.1 - 0.2 10.7 1.7 7.4 5.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 ETS76924.1 - 0.22 11.3 0.1 0.22 11.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 NACHT PF05729.7 ETS76924.1 - 0.37 10.4 7.2 2.1 7.9 0.2 3.0 3 0 0 3 3 2 0 NACHT domain AAA_5 PF07728.9 ETS76924.1 - 0.37 10.5 1.8 12 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 ETS76924.1 - 0.38 9.6 1.8 5.5 5.8 0.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 ETS76924.1 - 0.52 10.5 4.7 16 5.6 0.3 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETS76924.1 - 0.69 9.8 2.0 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 ETS76924.1 - 1.1 9.1 5.4 7.8 6.3 0.3 3.2 2 2 1 3 3 3 0 AAA domain AAA_10 PF12846.2 ETS76924.1 - 1.3 8.4 5.3 5.6 6.3 0.2 3.4 4 0 0 4 4 4 0 AAA-like domain AAA_18 PF13238.1 ETS76924.1 - 1.9 8.7 8.4 12 6.2 1.7 3.4 2 1 0 2 2 2 0 AAA domain Amidase PF01425.16 ETS76926.1 - 2.1e-60 204.8 0.6 1.9e-58 198.4 0.2 2.1 2 0 0 2 2 2 2 Amidase DUF21 PF01595.15 ETS76928.1 - 0.037 13.3 10.3 0.017 14.3 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 TRAM_LAG1_CLN8 PF03798.11 ETS76928.1 - 1.7 8.1 17.5 0.82 9.1 7.9 2.6 3 0 0 3 3 3 0 TLC domain Transferase PF02458.10 ETS76929.1 - 0.027 12.9 0.0 0.031 12.7 0.0 1.0 1 0 0 1 1 1 0 Transferase family Fungal_trans_2 PF11951.3 ETS76930.1 - 6.6e-35 120.4 0.8 9.9e-35 119.8 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ala_racemase_N PF01168.15 ETS76930.1 - 1.5e-15 57.3 0.1 2.6e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 ETS76930.1 - 8.7e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Zn_clus PF00172.13 ETS76930.1 - 0.014 15.3 2.1 0.032 14.1 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gln-synt_C PF00120.19 ETS76931.1 - 1.3e-53 181.7 0.0 1.8e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.17 ETS76932.1 - 4.6e-129 430.7 0.0 5.2e-129 430.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS76932.1 - 1.3e-06 27.4 0.0 2.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 ETS76933.1 - 8.9e-25 87.5 2.4 1.2e-24 87.0 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS76933.1 - 1.7e-17 64.0 0.0 2e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS76933.1 - 2e-07 30.8 1.5 3.2e-07 30.1 1.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS76933.1 - 0.0085 15.7 0.6 0.017 14.7 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS76933.1 - 0.04 12.9 0.4 0.089 11.8 0.3 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyoxalase PF00903.20 ETS76934.1 - 4.7e-10 39.5 0.0 1.2e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS76934.1 - 3.3e-09 37.3 0.0 5.5e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETS76934.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tannase PF07519.6 ETS76935.1 - 2.5e-82 277.1 0.0 2.2e-47 161.8 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS76935.1 - 1.1e-05 25.4 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS76935.1 - 5.2e-05 22.5 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Alpha-2-MRAP_N PF06400.6 ETS76936.1 - 0.023 14.3 0.2 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain Tyrosinase PF00264.15 ETS76937.1 - 1.9e-35 123.0 10.0 3e-35 122.4 7.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Sugar_tr PF00083.19 ETS76938.1 - 1.9e-67 227.8 23.6 2.3e-67 227.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS76938.1 - 5e-15 55.0 38.1 1.5e-11 43.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 ETS76939.1 - 4.6e-65 219.9 0.0 6.2e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 ETS76940.1 - 9.6e-09 34.9 10.6 4.5e-05 23.4 2.0 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS76940.1 - 1.9e-06 27.8 8.1 0.00034 20.7 1.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 ETS76940.1 - 1.7e-05 24.6 10.4 1.7e-05 24.6 7.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS76940.1 - 4.8e-05 22.3 1.8 9.9e-05 21.3 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 ETS76940.1 - 7.6e-05 22.8 1.7 0.0013 18.9 0.4 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS76940.1 - 0.014 15.2 2.4 0.062 13.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_primase_S PF01896.14 ETS76940.1 - 0.018 14.8 0.8 0.041 13.7 0.4 1.8 2 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit zf-met2 PF12907.2 ETS76940.1 - 0.036 14.0 0.0 11 6.1 0.0 3.1 2 0 0 2 2 2 0 Zinc-binding adh_short PF00106.20 ETS76941.1 - 1.9e-15 57.1 0.1 2.4e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS76941.1 - 8.6e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS76941.1 - 4.4e-07 29.9 0.0 6.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS76941.1 - 0.003 17.0 0.0 0.0067 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS76941.1 - 0.084 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 ETS76941.1 - 0.57 9.9 2.8 0.66 9.7 1.3 1.6 1 1 0 1 1 1 0 ThiF family PhyH PF05721.8 ETS76944.1 - 5.4e-17 62.5 0.0 7.2e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 ETS76945.1 - 4.3e-07 28.8 0.9 1.1e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain TENA_THI-4 PF03070.11 ETS76946.1 - 1.5e-14 54.2 0.0 5.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family DNA_primase_lrg PF04104.9 ETS76947.1 - 2.9e-81 272.5 0.0 5.9e-81 271.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit HMG_box_2 PF09011.5 ETS76947.1 - 0.03 14.6 0.7 0.066 13.5 0.5 1.5 1 0 0 1 1 1 0 HMG-box domain Sec16_C PF12931.2 ETS76948.1 - 1e-91 307.6 0.3 1.4e-91 307.1 0.2 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 ETS76948.1 - 3.8e-30 104.2 0.0 7.9e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region ketoacyl-synt PF00109.21 ETS76950.1 - 6.9e-71 238.6 0.0 2.9e-70 236.6 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS76950.1 - 2.6e-44 151.8 0.1 3.5e-43 148.1 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 ETS76950.1 - 2.3e-33 114.5 0.3 7.6e-33 112.8 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 ETS76950.1 - 4.1e-09 36.5 0.2 1e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS76950.1 - 7.4e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 ETS76950.1 - 0.0013 18.4 0.2 0.0054 16.4 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lactamase_B PF00753.22 ETS76951.1 - 5e-24 85.0 0.1 5.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS76951.1 - 1.8e-07 30.9 0.3 3.6e-07 29.9 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS76951.1 - 0.00015 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.6 ETS76952.1 - 9.7e-26 90.1 6.7 9.7e-26 90.1 4.6 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) RVP PF00077.15 ETS76952.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease EthD PF07110.6 ETS76953.1 - 5.9e-11 43.1 0.3 6.9e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 EthD domain Cu-oxidase_3 PF07732.10 ETS76954.1 - 2.5e-44 149.7 3.0 6.4e-43 145.2 1.9 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS76954.1 - 3.7e-40 136.6 1.9 2.7e-35 120.8 0.0 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 ETS76954.1 - 2.2e-30 105.6 1.1 4.1e-30 104.7 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase NAD_binding_10 PF13460.1 ETS76955.1 - 1.2e-11 44.9 0.0 1.5e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_11 PF08241.7 ETS76957.1 - 2.1e-13 50.5 0.0 3.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76957.1 - 1.4e-08 34.4 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76957.1 - 6.8e-08 33.0 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS76957.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76957.1 - 2.4e-07 30.5 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76957.1 - 6.5e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETS76957.1 - 0.0046 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 ETS76957.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS76957.1 - 0.0087 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain LacI PF00356.16 ETS76958.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Helicase_C_3 PF13625.1 ETS76958.1 - 0.037 13.7 0.1 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain MerR PF00376.18 ETS76958.1 - 0.093 12.3 0.0 0.56 9.8 0.0 2.2 1 1 0 1 1 1 0 MerR family regulatory protein AflR PF08493.5 ETS76959.1 - 2.7e-12 46.3 0.3 4.6e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 ETS76959.1 - 1.1e-07 31.6 12.7 1.1e-07 31.6 8.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_12 PF08242.7 ETS76960.1 - 1.4e-09 38.2 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS76960.1 - 2.8e-09 37.3 0.0 5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS76960.1 - 4.1e-09 36.9 0.1 1e-08 35.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS76960.1 - 4.5e-08 33.3 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS76960.1 - 2e-06 27.4 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS76960.1 - 2.3e-06 27.4 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS76960.1 - 1.3e-05 25.2 0.1 7.5e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS76960.1 - 5.6e-05 22.3 0.0 8.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS76960.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 ETS76960.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF4243 PF14027.1 ETS76961.1 - 1.3e-87 294.3 0.0 1.5e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Cu-oxidase_3 PF07732.10 ETS76962.1 - 2e-43 146.8 7.3 2.6e-42 143.2 0.2 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS76962.1 - 2.1e-36 124.4 11.6 2.1e-35 121.2 2.0 4.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS76962.1 - 5e-32 110.9 0.1 4.4e-29 101.4 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Pyr_redox_2 PF07992.9 ETS76963.1 - 1.9e-19 70.3 5.0 2.6e-18 66.6 3.5 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS76963.1 - 1.9e-13 50.6 0.3 5.3e-08 33.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS76963.1 - 1.7e-08 33.7 0.0 0.00029 19.8 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 ETS76963.1 - 1.3e-06 28.5 0.0 0.00036 20.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS76963.1 - 1.5e-06 27.4 3.1 0.00048 19.1 0.0 3.3 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS76963.1 - 4.5e-06 26.5 0.6 0.0044 16.7 0.0 3.1 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS76963.1 - 0.00012 21.2 0.1 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS76963.1 - 0.0023 17.9 0.4 0.095 12.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS76963.1 - 0.0039 16.1 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 ETS76963.1 - 0.0091 15.1 0.1 0.55 9.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 ETS76963.1 - 0.033 14.4 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 ETS76963.1 - 0.036 12.9 0.1 0.91 8.3 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.13 ETS76963.1 - 0.11 12.4 0.1 9.6 6.2 0.0 2.6 2 1 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 ETS76963.1 - 0.16 10.7 2.4 5.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS76963.1 - 0.33 11.0 2.2 20 5.2 0.2 2.8 2 2 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 ETS76963.1 - 0.33 9.5 1.1 2.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 ETS76963.1 - 0.55 8.6 3.3 13 4.0 0.2 3.0 3 1 1 4 4 4 0 HI0933-like protein Fungal_trans_2 PF11951.3 ETS76964.1 - 3.2e-50 170.8 8.7 4.7e-50 170.2 6.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76964.1 - 1.5e-08 34.3 5.1 3.5e-08 33.2 3.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_halogenase PF04820.9 ETS76965.1 - 8.1e-30 103.8 0.0 1.1e-14 53.9 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 ETS76965.1 - 1.1e-11 44.3 0.0 1.2e-10 40.9 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS76965.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS76965.1 - 9.4e-06 25.5 0.1 3.9e-05 23.5 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS76965.1 - 1.4e-05 24.2 0.2 2.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS76965.1 - 2.9e-05 23.3 0.2 6.5e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS76965.1 - 8.4e-05 21.7 0.1 0.0018 17.3 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 ETS76965.1 - 9.1e-05 21.0 0.1 0.00017 20.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 ETS76965.1 - 0.00018 20.5 0.1 0.00028 19.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS76965.1 - 0.00025 20.0 0.1 0.0004 19.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS76965.1 - 0.0058 17.0 0.1 0.019 15.3 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETS76965.1 - 0.019 14.7 0.1 0.086 12.6 0.2 1.9 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.7 ETS76965.1 - 0.035 13.0 0.1 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS76965.1 - 0.035 13.7 0.1 0.15 11.6 0.0 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS76965.1 - 0.088 12.2 0.1 0.64 9.4 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 ETS76965.1 - 0.13 12.4 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.24 ETS76967.1 - 2.7e-17 63.2 0.0 7.9e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS76967.1 - 0.00043 20.3 0.3 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS76967.1 - 0.0062 17.3 0.0 0.02 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS76967.1 - 0.0067 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS76967.1 - 0.013 15.6 1.5 0.14 12.2 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 ETS76967.1 - 0.033 13.9 0.1 0.094 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 ETS76967.1 - 0.14 11.1 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2721 PF11026.3 ETS76968.1 - 0.0087 15.6 0.5 0.018 14.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Pkip-1 PF06878.6 ETS76968.1 - 0.012 15.5 0.4 0.028 14.3 0.2 1.6 1 1 0 1 1 1 0 Pkip-1 protein Peptidase_M16 PF00675.15 ETS76969.1 - 1.9e-30 105.5 4.3 3.4e-30 104.7 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS76969.1 - 2.8e-07 30.3 0.0 6.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain tRNA-synt_2 PF00152.15 ETS76971.1 - 6.9e-33 113.8 0.0 9.2e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) 2OG-FeII_Oxy PF03171.15 ETS76972.1 - 0.00014 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS76972.1 - 0.0016 18.9 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Haem_oxygenas_2 PF14518.1 ETS76973.1 - 1.6e-12 47.5 0.0 8.3e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Iron-containing redox enzyme MFS_1 PF07690.11 ETS76975.1 - 5.1e-41 140.5 47.0 1.5e-36 125.8 24.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 ETS76976.1 - 1.6e-63 214.8 0.0 2.4e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 ETS76977.1 - 6.7e-22 77.6 0.2 2.2e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76977.1 - 2.4e-06 27.3 10.1 2.4e-06 27.3 7.0 2.2 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC_N PF03476.11 ETS76978.1 - 1.4e-13 50.5 0.0 9.8e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS76978.1 - 1.3e-12 47.2 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain DBR1 PF05011.8 ETS76979.1 - 4e-47 159.7 0.2 5.9e-47 159.1 0.1 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 ETS76979.1 - 2.7e-10 39.9 2.3 4.2e-10 39.3 1.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aldo_ket_red PF00248.16 ETS76980.1 - 1.9e-60 204.0 0.0 2.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.15 ETS76981.1 - 6e-37 127.2 14.7 7.6e-37 126.8 10.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related EutH PF04346.7 ETS76981.1 - 0.0038 16.2 2.8 0.0047 15.9 1.9 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH Sdh_cyt PF01127.17 ETS76981.1 - 3.8 7.3 12.6 0.21 11.4 4.2 2.2 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ank_2 PF12796.2 ETS76982.1 - 4.5e-29 100.6 0.6 3.2e-13 49.8 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76982.1 - 3.7e-26 89.5 2.2 2.3e-07 30.2 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 ETS76982.1 - 3.2e-19 67.0 2.1 0.00011 22.0 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 ETS76982.1 - 3.2e-19 68.5 5.5 4.5e-09 36.2 0.2 5.2 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS76982.1 - 4.7e-17 62.0 2.3 1.3e-09 38.2 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 ETS76982.1 - 3.2e-10 39.3 0.0 7.9e-10 38.0 0.0 1.7 2 0 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.7 ETS76982.1 - 3e-09 36.7 0.5 1.1e-08 34.9 0.0 2.2 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 ETS76982.1 - 0.027 14.6 0.0 0.18 11.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.9 ETS76982.1 - 0.028 13.4 0.0 0.064 12.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 ETS76982.1 - 0.055 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Shigella_OspC PF06128.6 ETS76982.1 - 0.077 12.4 0.0 7.5 5.9 0.0 2.5 1 1 0 2 2 2 0 Shigella flexneri OspC protein DUF2075 PF09848.4 ETS76982.1 - 0.13 11.1 0.1 0.81 8.6 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) HlyIII PF03006.15 ETS76983.1 - 1.1e-41 142.6 14.1 1.5e-41 142.2 9.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_S8 PF00082.17 ETS76984.1 - 1.1e-23 83.7 0.0 2.2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 ETS76986.1 - 1.1e-68 227.6 2.8 2.5e-14 53.3 0.0 6.6 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS76986.1 - 8.5e-58 189.4 25.2 9.9e-09 34.5 0.1 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 ETS76986.1 - 2.1e-50 168.2 12.1 8.4e-11 42.0 0.4 8.6 3 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS76986.1 - 7.6e-44 146.7 11.1 1.3e-10 41.1 0.6 8.2 3 1 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS76986.1 - 5.7e-39 128.2 11.2 0.00027 20.8 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat zf-C2H2_4 PF13894.1 ETS76986.1 - 1.7 9.1 5.9 55 4.4 0.0 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Ribonuclease PF00545.15 ETS76987.1 - 9.3e-10 38.4 0.3 1.3e-09 38.0 0.2 1.2 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 ETS76988.1 - 1e-16 61.2 0.0 4.6e-16 59.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) UL73_N PF12522.3 ETS76989.1 - 0.19 11.2 4.9 0.39 10.3 3.4 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal HCO3_cotransp PF00955.16 ETS76991.1 - 1.9e-71 241.2 7.6 7.6e-42 143.6 2.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Peptidase_M41 PF01434.13 ETS76992.1 - 1.4e-74 250.2 0.0 2.5e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 ETS76992.1 - 1e-41 142.2 0.0 2.3e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 ETS76992.1 - 1.4e-12 47.7 0.0 5.4e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 ETS76992.1 - 0.0014 18.3 0.0 0.0055 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 ETS76992.1 - 0.0031 16.2 0.0 0.0054 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 ETS76992.1 - 0.0036 17.4 0.0 0.69 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS76992.1 - 0.0072 16.0 1.3 0.037 13.7 0.5 2.3 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 ETS76992.1 - 0.0094 15.0 0.1 0.029 13.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS76992.1 - 0.01 15.2 0.7 0.037 13.4 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS76992.1 - 0.012 16.3 0.0 0.059 14.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 ETS76992.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETS76992.1 - 0.022 14.7 1.1 0.37 10.7 0.1 3.0 2 1 1 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 ETS76992.1 - 0.024 13.7 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 ETS76992.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 ETS76992.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS76992.1 - 0.19 10.8 0.2 0.39 9.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Fungal_trans PF04082.13 ETS76993.1 - 3.1e-28 98.3 0.0 7.3e-28 97.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS76993.1 - 1.1e-10 41.2 11.3 1.8e-10 40.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP-alpha_N PF04086.8 ETS76993.1 - 1.7 7.9 11.9 0.056 12.8 0.4 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2360 PF10152.4 ETS76993.1 - 4.6 7.5 12.6 6.7 6.9 2.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Rifin_STEVOR PF02009.11 ETS76994.1 - 2.8 7.4 6.8 5.4 6.5 0.0 2.4 2 1 0 2 2 2 0 Rifin/stevor family Peptidase_C37 PF05416.7 ETS76995.1 - 0.074 11.3 6.3 0.089 11.0 4.4 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Skp1 PF01466.14 ETS76995.1 - 0.46 10.5 3.1 0.84 9.7 2.2 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain IGPD PF00475.13 ETS76996.1 - 3e-59 199.0 0.6 4.1e-59 198.5 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MARVEL PF01284.18 ETS76997.1 - 0.00014 21.7 18.9 0.01 15.6 13.3 2.2 1 1 1 2 2 2 2 Membrane-associating domain DUF912 PF06024.7 ETS76997.1 - 0.05 13.6 0.1 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BPD_transp_2 PF02653.11 ETS76997.1 - 0.47 9.3 9.5 0.68 8.8 6.6 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ion_trans PF00520.26 ETS76997.1 - 0.56 9.4 7.6 0.85 8.8 5.3 1.2 1 0 0 1 1 1 0 Ion transport protein DUF2237 PF09996.4 ETS77001.1 - 7e-30 102.9 0.1 1.3e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) MFS_1 PF07690.11 ETS77002.1 - 7.6e-46 156.4 23.9 7.6e-46 156.4 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77002.1 - 2.8e-18 65.7 9.1 2.8e-18 65.7 6.3 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 ETS77002.1 - 0.55 8.2 8.2 1.4 6.8 3.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Nop14 PF04147.7 ETS77003.1 - 0.034 12.0 4.5 0.044 11.7 3.1 1.0 1 0 0 1 1 1 0 Nop14-like family Staphostatin_B PF09023.5 ETS77003.1 - 0.056 13.2 0.7 0.095 12.5 0.1 1.6 2 0 0 2 2 2 0 Staphostatin B CoA_binding PF02629.14 ETS77004.1 - 3e-27 94.9 3.6 7.9e-27 93.6 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 ETS77004.1 - 5.4e-24 84.5 0.3 8.6e-24 83.8 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 ETS77004.1 - 6.3e-07 29.0 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 ETS77004.1 - 0.00078 19.5 0.0 0.0027 17.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 ETS77004.1 - 0.0085 16.6 0.1 0.02 15.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA PF00004.24 ETS77005.1 - 4.5e-41 140.1 0.0 8.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS77005.1 - 5.7e-07 29.7 0.2 0.0002 21.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETS77005.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 ETS77005.1 - 1.1e-05 24.5 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETS77005.1 - 2.3e-05 24.1 0.0 6.9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS77005.1 - 0.00021 21.3 0.1 0.00098 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 ETS77005.1 - 0.00033 19.7 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 ETS77005.1 - 0.0011 18.9 0.1 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS77005.1 - 0.002 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS77005.1 - 0.0035 18.1 0.3 0.011 16.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS77005.1 - 0.0066 16.1 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 ETS77005.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 ETS77005.1 - 0.0078 15.8 0.2 0.34 10.5 0.1 2.5 2 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 ETS77005.1 - 0.0086 15.1 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 ETS77005.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS77005.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 ETS77005.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS77005.1 - 0.015 14.6 1.7 0.24 10.7 0.3 2.5 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 ETS77005.1 - 0.021 13.5 0.1 0.045 12.4 0.1 1.5 1 1 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 ETS77005.1 - 0.025 13.6 0.2 0.43 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 ETS77005.1 - 0.027 13.7 1.4 0.2 10.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 ETS77005.1 - 0.035 12.9 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 ETS77005.1 - 0.043 13.9 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 ETS77005.1 - 0.046 13.3 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS77005.1 - 0.053 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 ETS77005.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_S15 PF02129.13 ETS77006.1 - 2.6e-37 128.7 0.4 2.7e-34 118.8 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS77006.1 - 4.5e-27 95.3 0.2 6.8e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS77006.1 - 0.00022 21.1 0.1 0.00048 20.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS77006.1 - 0.034 14.0 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase FAD_binding_3 PF01494.14 ETS77007.1 - 2.1e-32 112.5 0.0 9.4e-32 110.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.16 ETS77007.1 - 0.064 13.0 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 ETS77007.1 - 0.16 10.8 0.1 0.37 9.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 ETS77007.1 - 0.19 10.1 0.1 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Polysacc_deac_1 PF01522.16 ETS77008.1 - 1.2e-12 47.5 0.0 2.5e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase Dioxygenase_C PF00775.16 ETS77009.1 - 7.5e-51 171.9 0.0 1.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS77009.1 - 2.8e-18 65.6 0.1 5.3e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 ETS77009.1 - 0.076 13.0 0.0 0.29 11.1 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 ETS77010.1 - 2.6e-17 62.5 0.7 4.3e-17 61.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCHC PF00098.18 ETS77011.1 - 4.9e-07 29.3 9.1 3.2e-06 26.8 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 ETS77011.1 - 0.00057 19.5 5.0 0.12 12.0 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.1 ETS77011.1 - 0.082 12.4 0.4 0.19 11.2 0.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 ETS77011.1 - 0.091 12.4 5.5 0.72 9.5 0.4 2.7 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 ETS77011.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.5 1 1 1 2 2 2 0 Zinc knuckle Hus1 PF04005.7 ETS77012.1 - 2.1e-95 319.0 0.0 2.4e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.1 ETS77013.1 - 4.2e-09 36.0 2.5 4.2e-09 36.0 1.7 3.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 ETS77013.1 - 1.4e-06 27.8 11.0 0.00037 20.0 0.0 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS77013.1 - 3.2e-05 23.8 1.0 3.2e-05 23.8 0.7 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS77013.1 - 4.2e-05 23.5 2.2 4.2e-05 23.5 1.5 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETS77013.1 - 0.00044 19.9 0.2 0.00044 19.9 0.1 2.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS77013.1 - 0.00045 19.8 0.9 0.00045 19.8 0.6 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS77013.1 - 0.12 12.0 10.3 0.67 9.7 0.1 2.9 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 ETS77013.1 - 0.16 11.9 8.3 0.6 10.1 4.6 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 ETS77013.1 - 0.36 10.7 15.5 0.71 9.8 0.6 3.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 ETS77013.1 - 5.4 6.9 9.4 0.38 10.6 1.7 2.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger FH2 PF02181.18 ETS77014.1 - 9e-81 271.5 5.1 9e-81 271.5 3.6 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 ETS77014.1 - 6.4e-64 214.7 0.1 2.1e-63 213.1 0.1 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 ETS77014.1 - 2.3e-52 177.2 2.6 3.9e-51 173.2 0.5 2.9 1 1 1 2 2 2 2 Diaphanous FH3 Domain Ring_hydroxyl_A PF00848.14 ETS77016.1 - 5.2e-37 127.5 0.8 1.1e-36 126.4 0.5 1.5 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS77016.1 - 1.1e-13 50.5 0.0 2.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 ETS77017.1 - 4.6e-46 157.3 0.1 6.3e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS77017.1 - 1.5e-05 24.7 0.1 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS77017.1 - 5.9e-05 23.2 0.1 0.001 19.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77017.1 - 0.00044 20.2 0.0 0.0015 18.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS77017.1 - 0.0013 17.6 0.2 0.0094 14.8 0.0 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS77017.1 - 0.0015 18.4 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS77017.1 - 0.018 13.6 0.1 0.17 10.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 ETS77017.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 ETS77017.1 - 0.028 13.5 0.0 3.3 6.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS77017.1 - 0.032 13.1 0.0 0.098 11.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 ETS77017.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 ETS77018.1 - 8.7e-11 41.1 0.6 1.5e-10 40.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 ETS77019.1 - 9.2e-65 218.8 0.5 1.5e-64 218.2 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 ETS77019.1 - 4.2e-56 189.6 0.0 7.6e-56 188.8 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS77019.1 - 3.6e-17 62.1 0.2 1.2e-16 60.5 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.22 ETS77019.1 - 0.00025 21.3 0.1 0.0087 16.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS77019.1 - 0.00059 19.8 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.1 ETS77019.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS77019.1 - 0.0015 17.2 0.0 0.036 12.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS77019.1 - 0.0015 17.4 0.2 0.003 16.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain SoxG PF04268.7 ETS77019.1 - 0.002 17.9 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family NAD_binding_9 PF13454.1 ETS77019.1 - 0.0056 16.4 0.1 0.045 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.16 ETS77019.1 - 0.0089 15.8 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 ETS77019.1 - 0.012 15.7 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 ETS77019.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS77019.1 - 0.034 14.0 0.5 0.23 11.3 0.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 ETS77019.1 - 0.064 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 ETS77019.1 - 0.15 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain An_peroxidase PF03098.10 ETS77020.1 - 4.5e-77 259.6 0.0 6.8e-75 252.4 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 ETS77020.1 - 1.2e-09 37.2 0.1 5.3e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 ETS77021.1 - 1.9e-73 247.2 0.4 2.4e-73 246.8 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 ETS77021.1 - 0.00065 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 ETS77021.1 - 0.045 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF500 PF04366.7 ETS77022.1 - 3e-41 139.8 1.8 2.5e-40 136.8 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF500) zf-C2H2_7 PF15269.1 ETS77023.1 - 0.17 11.7 0.8 0.29 11.0 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger Peptidase_M24 PF00557.19 ETS77024.1 - 3.1e-39 134.6 0.1 4.5e-39 134.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS77024.1 - 2.3e-11 44.2 0.1 3.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Amidinotransf PF02274.12 ETS77024.1 - 0.11 11.5 0.1 3.8 6.5 0.0 2.8 1 1 3 4 4 4 0 Amidinotransferase Peptidase_M28 PF04389.12 ETS77025.1 - 1.5e-27 96.4 0.0 2.7e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF3687 PF12459.3 ETS77025.1 - 0.11 11.8 0.4 0.22 10.7 0.3 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Gsf2 PF11055.3 ETS77025.1 - 0.15 10.5 0.1 0.2 10.1 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 zf-CCHC PF00098.18 ETS77027.1 - 2.6e-11 42.8 9.5 1.8e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 ETS77027.1 - 1.8e-08 33.9 0.1 3.2e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 ETS77027.1 - 8.6e-07 28.5 4.9 0.00094 18.8 1.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 ETS77027.1 - 1.2e-05 24.8 0.2 2.8e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 ETS77027.1 - 0.00086 18.9 7.3 0.21 11.2 0.5 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 ETS77027.1 - 0.001 18.6 6.2 0.25 11.0 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle FliT PF05400.8 ETS77027.1 - 0.81 10.1 3.6 27 5.2 0.5 3.1 3 0 0 3 3 3 0 Flagellar protein FliT ELO PF01151.13 ETS77028.1 - 1e-62 211.7 19.1 1.2e-62 211.4 13.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.11 ETS77029.1 - 2e-39 133.9 0.4 2.6e-39 133.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Annexin PF00191.15 ETS77029.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Annexin DHC_N1 PF08385.7 ETS77029.1 - 0.078 11.3 0.1 0.98 7.7 0.0 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 SGL PF08450.7 ETS77030.1 - 1.1e-58 198.4 0.0 1.7e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DUF839 PF05787.8 ETS77030.1 - 0.037 12.9 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.6 ETS77030.1 - 0.3 11.2 3.0 15 5.9 0.0 3.7 5 0 0 5 5 5 0 Two component regulator propeller DUF2666 PF10869.3 ETS77032.1 - 0.23 11.4 5.5 0.65 10.0 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) NYD-SP28_assoc PF14775.1 ETS77032.1 - 0.43 10.3 4.8 0.19 11.4 0.1 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Noc2 PF03715.8 ETS77032.1 - 0.55 9.0 2.5 1.3 7.8 1.7 1.5 1 0 0 1 1 1 0 Noc2p family AAA_5 PF07728.9 ETS77033.1 - 3e-09 36.7 0.0 6.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS77033.1 - 7.4e-09 35.7 0.2 2.8e-08 33.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETS77033.1 - 2.2e-07 31.1 0.0 2.1e-06 27.9 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 ETS77033.1 - 0.00051 19.8 0.0 0.003 17.4 0.0 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 ETS77033.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Torsin PF06309.6 ETS77033.1 - 0.0016 18.3 0.1 0.0048 16.7 0.0 1.8 2 0 0 2 2 1 1 Torsin Mg_chelatase PF01078.16 ETS77033.1 - 0.0048 16.0 0.3 1.1 8.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 ETS77033.1 - 0.0076 15.3 0.1 0.038 13.0 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETS77033.1 - 0.013 15.5 0.1 0.067 13.1 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 ETS77033.1 - 0.019 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_4 PF13637.1 ETS77033.1 - 0.022 15.2 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNA_helicase PF00910.17 ETS77033.1 - 0.031 14.4 0.0 0.097 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 ETS77033.1 - 0.035 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS77033.1 - 0.038 13.6 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 ETS77033.1 - 0.064 13.3 0.2 0.67 10.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_6 PF12774.2 ETS77033.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 IstB_IS21 PF01695.12 ETS77033.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UBA_4 PF14555.1 ETS77033.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain AAA_17 PF13207.1 ETS77033.1 - 0.1 13.4 1.5 0.3 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS77033.1 - 8.2 6.6 10.5 3.9e+02 1.2 7.3 2.6 1 1 0 1 1 1 0 AAA domain VWA_2 PF13519.1 ETS77034.1 - 1.6e-08 34.8 0.1 6.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain TPP_enzyme_C PF02775.16 ETS77034.1 - 0.02 14.4 0.0 0.061 12.8 0.0 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TMCO5 PF14992.1 ETS77034.1 - 0.21 10.6 32.1 0.13 11.4 20.4 1.9 1 1 1 2 2 2 0 TMCO5 family Reo_sigmaC PF04582.7 ETS77034.1 - 2.9 7.0 9.1 2.1 7.4 4.8 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Herpes_UL25 PF01499.11 ETS77034.1 - 4.9 5.3 25.0 0.89 7.7 6.0 2.2 1 1 1 2 2 2 0 Herpesvirus UL25 family Ribonuc_L-PSP PF01042.16 ETS77035.1 - 1.4e-19 70.0 0.0 1.6e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_6 PF13458.1 ETS77035.1 - 0.096 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Fungal_trans_2 PF11951.3 ETS77038.1 - 1.5e-41 142.3 0.8 8.1e-27 93.8 0.1 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 ETS77038.1 - 8.6e-17 61.7 0.0 1.8e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS77038.1 - 3.8e-08 32.8 0.0 5.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS77038.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS77038.1 - 0.0037 16.0 0.0 0.006 15.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 ETS77038.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 ETS77038.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS77038.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 ETS77039.1 - 1.6e-24 86.2 30.1 1.6e-24 86.2 20.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS77039.1 - 5.5 7.0 9.8 3.3 7.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Hydantoinase_B PF02538.9 ETS77040.1 - 6.3e-174 579.0 0.0 9.3e-174 578.5 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS77040.1 - 1.3e-92 309.9 0.0 2.4e-92 309.1 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS77040.1 - 1.5e-56 190.7 0.3 5.2e-55 185.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 ETS77040.1 - 0.16 11.3 0.8 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 ETS77041.1 - 5.3e-73 238.5 18.6 9e-09 34.8 0.0 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 ETS77041.1 - 3.3e-44 149.9 0.5 5.1e-44 149.3 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 ETS77041.1 - 1.9e-09 36.7 3.9 0.72 8.5 0.0 5.8 5 1 0 5 5 5 4 Nup133 N terminal like ADP_PFK_GK PF04587.10 ETS77041.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Lipase_GDSL PF00657.17 ETS77042.1 - 1.1e-10 41.7 0.9 1.5e-10 41.3 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS77042.1 - 1.5e-09 38.2 3.2 2.3e-09 37.6 2.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2190 PF09956.4 ETS77042.1 - 0.4 10.4 3.6 29 4.4 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2190) Baculo_PEP_C PF04513.7 ETS77044.1 - 0.019 14.7 3.7 6.4 6.6 0.2 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0203 PF05254.7 ETS77044.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF4515 PF14988.1 ETS77044.1 - 0.093 12.3 3.5 0.22 11.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) PilJ PF13675.1 ETS77044.1 - 0.25 11.6 4.1 0.26 11.6 0.3 2.6 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin-6_N PF09177.6 ETS77044.1 - 0.67 10.3 7.3 20 5.6 0.0 4.0 2 1 1 4 4 4 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 ETS77044.1 - 0.88 9.8 5.4 4.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 ETS77044.1 - 0.94 9.3 4.4 29 4.5 0.0 3.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) CorA PF01544.13 ETS77045.1 - 0.012 14.6 1.5 0.07 12.1 0.2 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PcfJ PF14284.1 ETS77045.1 - 0.075 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 PcfJ-like protein Sirohm_synth_M PF14824.1 ETS77045.1 - 0.094 11.7 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central ADH_zinc_N PF00107.21 ETS77048.1 - 6.5e-07 28.9 0.0 8.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TehB PF03848.9 ETS77048.1 - 0.059 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB ADH_N PF08240.7 ETS77049.1 - 3.5e-07 29.9 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Baculo_PEP_C PF04513.7 ETS77050.1 - 0.3 10.9 2.7 11 5.7 0.3 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VWA PF00092.23 ETS77052.1 - 0.1 12.3 0.0 0.38 10.4 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain WD40 PF00400.27 ETS77053.1 - 2.8e-150 483.5 62.0 4.4e-13 48.5 0.1 12.8 13 0 0 13 13 12 12 WD domain, G-beta repeat NACHT PF05729.7 ETS77053.1 - 1.2e-18 67.3 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 ETS77053.1 - 6.8e-10 38.3 0.0 1.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Nup160 PF11715.3 ETS77053.1 - 5.3e-09 34.7 37.5 0.22 9.6 4.0 9.7 1 1 6 7 7 7 6 Nucleoporin Nup120/160 DUF3312 PF11768.3 ETS77053.1 - 3.3e-05 22.3 0.2 0.75 7.9 0.0 5.0 3 2 4 7 7 7 2 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 ETS77053.1 - 0.00016 21.2 18.2 0.057 12.8 5.5 3.9 1 1 2 3 3 3 3 PQQ-like domain AAA_16 PF13191.1 ETS77053.1 - 0.0038 17.2 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS77053.1 - 0.0078 16.3 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS77053.1 - 0.01 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PQQ_3 PF13570.1 ETS77053.1 - 0.035 14.3 1.2 41 4.6 0.0 5.2 5 0 0 5 5 4 0 PQQ-like domain RNA_pol_Rpb4 PF03874.11 ETS77053.1 - 0.047 13.7 0.3 5.1 7.1 0.2 2.7 1 1 0 1 1 1 0 RNA polymerase Rpb4 ABC1 PF03109.11 ETS77054.1 - 2.4e-34 117.8 0.0 4.9e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Filo_VP35 PF02097.10 ETS77054.1 - 0.032 13.4 0.3 0.057 12.6 0.2 1.3 1 0 0 1 1 1 0 Filoviridae VP35 DUF947 PF06102.7 ETS77055.1 - 1.3e-44 152.0 18.3 2.1e-44 151.2 12.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Ank_2 PF12796.2 ETS77057.1 - 1e-20 73.8 0.6 2.3e-11 43.8 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77057.1 - 2.6e-16 58.5 0.1 0.0004 20.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETS77057.1 - 1e-15 57.3 0.1 1.3e-06 28.4 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77057.1 - 1e-12 46.9 0.2 0.073 13.3 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 ETS77057.1 - 2.8e-12 46.8 0.0 0.00083 19.8 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 ETS77057.1 - 0.026 14.8 0.1 0.026 14.8 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger TPR_7 PF13176.1 ETS77057.1 - 0.1 12.4 0.1 0.4 10.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pex14_N PF04695.8 ETS77057.1 - 3.2 7.8 7.0 1.4 8.9 0.3 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sugar_tr PF00083.19 ETS77058.1 - 5.6e-62 209.7 14.7 9.2e-62 209.0 10.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77058.1 - 5.3e-11 41.8 37.0 1.8e-06 26.9 9.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.4 ETS77058.1 - 0.12 11.8 3.6 0.9 9.0 0.1 2.7 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 NIF PF03031.13 ETS77059.1 - 1.9e-18 66.6 0.3 5.4e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Spt20 PF12090.3 ETS77059.1 - 0.22 10.8 4.3 0.37 10.0 3.0 1.4 1 0 0 1 1 1 0 Spt20 family TAF4 PF05236.9 ETS77059.1 - 0.59 9.3 7.3 28 3.8 0.0 2.1 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.7 ETS77059.1 - 2.7 7.8 7.8 4 7.2 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_S9 PF00380.14 ETS77061.1 - 6.5e-37 126.4 0.1 2.3e-36 124.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 EF1G PF00647.14 ETS77062.1 - 6.8e-39 131.8 0.1 1.3e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 ETS77062.1 - 3.9e-13 49.1 0.1 8.3e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS77062.1 - 1.2e-12 47.7 0.0 5.6e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS77062.1 - 2.8e-11 43.1 0.2 1.2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS77062.1 - 3.9e-11 43.0 0.0 8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS77062.1 - 6.1e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS77062.1 - 4.1e-06 27.1 0.1 1.7e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_1 PF00036.27 ETS77063.1 - 1.9e-22 76.7 12.5 4.1e-07 28.8 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS77063.1 - 1.8e-19 69.6 1.9 9.2e-13 48.1 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS77063.1 - 1.9e-16 58.4 4.3 6e-05 22.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETS77063.1 - 2.5e-15 55.0 10.7 1.8e-06 26.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 ETS77063.1 - 4.3e-14 51.8 10.3 2.1e-05 24.0 0.9 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 ETS77063.1 - 9.4e-07 28.5 4.7 0.0015 18.2 0.3 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETS77063.1 - 9.4e-05 22.4 0.0 0.00021 21.3 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 ETS77063.1 - 0.11 12.4 0.0 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain EPL1 PF10513.4 ETS77064.1 - 1.5e-24 87.0 3.5 1.5e-24 87.0 2.4 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like Peptidase_M22 PF00814.20 ETS77065.1 - 1.3e-78 264.2 0.0 1.6e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.10 ETS77066.1 - 1.2e-22 79.7 1.3 1.6e-21 76.0 0.1 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Pkinase PF00069.20 ETS77068.1 - 1.6e-63 214.3 0.0 1.9e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77068.1 - 7.4e-31 107.1 0.0 9.7e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS77068.1 - 0.0082 15.1 0.0 0.014 14.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like CMAS PF02353.15 ETS77069.1 - 2.1e-36 125.4 0.7 3.2e-36 124.8 0.5 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 ETS77069.1 - 1.1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77069.1 - 3.9e-16 59.3 0.0 6.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77069.1 - 3.9e-13 49.9 0.0 1.4e-12 48.1 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS77069.1 - 8.6e-13 48.3 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77069.1 - 1.3e-10 41.6 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS77069.1 - 5.5e-10 39.5 0.0 9.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS77069.1 - 4.7e-09 35.8 0.0 1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS77069.1 - 1e-06 28.0 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 ETS77069.1 - 4.6e-06 26.3 0.0 8.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GidB PF02527.10 ETS77069.1 - 0.00017 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 ETS77069.1 - 0.00064 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 ETS77069.1 - 0.00091 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 ETS77069.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 ETS77069.1 - 0.0011 18.0 0.0 0.0078 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Nol1_Nop2_Fmu PF01189.12 ETS77069.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_9 PF08003.6 ETS77069.1 - 0.021 13.5 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Recep_L_domain PF01030.19 ETS77069.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Receptor L domain UCH PF00443.24 ETS77070.1 - 2.4e-28 99.0 0.0 3.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS77070.1 - 2.5e-12 46.7 0.1 4.6e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Es2 PF09751.4 ETS77071.1 - 1.2e-105 354.2 1.4 1.7e-105 353.8 1.0 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 DUF3433 PF11915.3 ETS77072.1 - 1.4e-40 137.2 7.6 8.3e-24 83.5 0.3 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Med3 PF11593.3 ETS77073.1 - 0.057 12.6 15.7 0.086 12.0 10.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_61 PF03443.9 ETS77073.1 - 0.06 13.1 0.0 0.06 13.1 0.0 2.4 2 1 1 3 3 3 0 Glycosyl hydrolase family 61 Cu-oxidase_3 PF07732.10 ETS77074.1 - 8.1e-42 141.6 5.7 4.6e-41 139.2 1.3 3.8 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS77074.1 - 1e-41 142.4 0.3 2.1e-41 141.4 0.2 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS77074.1 - 5.5e-38 129.6 9.0 2.8e-36 124.0 0.6 4.1 4 0 0 4 4 4 2 Multicopper oxidase MRP-S35 PF10246.4 ETS77074.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 AIG2 PF06094.7 ETS77075.1 - 4.9e-11 43.0 0.1 7.4e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family FAT PF02259.18 ETS77076.1 - 1.5e-73 247.8 4.4 3e-73 246.8 3.0 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 ETS77076.1 - 1.8e-25 89.8 0.7 1.1e-24 87.2 0.3 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 ETS77076.1 - 7.8e-11 41.2 0.2 2.2e-10 39.7 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 ETS77076.1 - 0.0058 16.2 10.3 16 5.2 0.1 5.8 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.1 ETS77076.1 - 0.0073 16.0 6.8 0.12 12.1 0.9 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS77076.1 - 0.12 12.0 11.3 19 5.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS77076.1 - 0.2 11.6 12.4 4.2 7.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SR-25 PF10500.4 ETS77076.1 - 0.84 9.0 9.2 1.7 8.0 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_17 PF13431.1 ETS77076.1 - 4.9 7.6 10.1 11 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase PF00702.21 ETS77077.1 - 3e-16 60.4 0.0 1.2e-15 58.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETS77077.1 - 5.7e-16 58.2 0.0 1.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETS77077.1 - 3.9e-10 40.2 0.0 9.5e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS77077.1 - 2.4e-06 27.4 0.0 2.7e-05 24.0 0.0 2.6 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS77077.1 - 0.0017 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glycogen_syn PF05693.8 ETS77078.1 - 0 1144.8 0.0 0 1144.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 ETS77078.1 - 5.2e-06 25.9 0.0 0.013 14.9 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 ETS77078.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 ETS77078.1 - 2.4e-05 24.5 0.0 5.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F-box-like PF12937.2 ETS77080.1 - 6.5e-07 28.9 0.1 1.8e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 ETS77080.1 - 0.0012 18.3 3.5 0.21 11.2 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 ETS77080.1 - 0.044 13.4 1.8 7.1 6.4 0.1 2.5 2 0 0 2 2 2 0 F-box domain ABC_tran PF00005.22 ETS77081.1 - 6.3e-39 133.4 0.0 1.5e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS77081.1 - 1.3e-32 113.3 18.6 9.7e-28 97.3 6.7 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS77081.1 - 4.2e-10 40.0 0.1 0.04 13.8 0.0 4.3 2 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 ETS77081.1 - 4.5e-07 29.2 0.3 0.021 14.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS77081.1 - 2.1e-06 27.8 0.0 0.048 13.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS77081.1 - 2.4e-06 28.3 0.0 0.13 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 ETS77081.1 - 4.2e-06 26.1 6.5 0.73 9.0 0.2 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS77081.1 - 1e-05 25.6 0.6 0.075 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 ETS77081.1 - 2.1e-05 24.8 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS77081.1 - 3e-05 23.0 0.0 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 ETS77081.1 - 3.4e-05 23.3 0.1 0.13 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 ETS77081.1 - 5.4e-05 23.1 0.4 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 ETS77081.1 - 7.7e-05 22.5 0.4 0.13 12.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS77081.1 - 9.7e-05 21.6 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS77081.1 - 0.00034 20.1 0.2 1.2 8.4 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 ETS77081.1 - 0.00037 20.2 0.2 0.56 9.9 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETS77081.1 - 0.00055 20.4 0.1 0.019 15.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS77081.1 - 0.00056 19.8 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 ETS77081.1 - 0.00089 17.9 0.1 0.054 12.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 ETS77081.1 - 0.007 16.7 0.2 2.6 8.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS77081.1 - 0.0073 15.4 0.1 0.67 9.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS77081.1 - 0.01 15.3 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 ETS77081.1 - 0.012 15.2 0.2 0.56 9.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 ETS77081.1 - 0.014 15.2 0.3 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA PF00004.24 ETS77081.1 - 0.022 14.9 0.0 1.7 8.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETS77081.1 - 0.023 14.8 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 ETS77081.1 - 0.04 13.3 1.5 0.61 9.5 0.0 3.0 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 ETS77081.1 - 0.042 13.5 0.3 9.7 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 ETS77081.1 - 0.064 12.7 0.0 7.3 5.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 ETS77081.1 - 0.07 12.6 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.8 ETS77081.1 - 0.08 11.8 0.0 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 ETS77081.1 - 0.14 11.3 0.2 22 4.1 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.22 ETS77081.1 - 0.14 11.5 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Adeno_IVa2 PF02456.10 ETS77081.1 - 0.2 10.2 0.0 17 3.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein SbcCD_C PF13558.1 ETS77081.1 - 0.26 11.2 10.3 2.5 8.0 0.2 4.5 5 2 0 5 5 3 0 Putative exonuclease SbcCD, C subunit AAA_PrkA PF08298.6 ETS77081.1 - 0.38 9.3 0.1 22 3.6 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain Arch_ATPase PF01637.13 ETS77081.1 - 0.48 10.0 0.0 22 4.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DHH PF01368.15 ETS77083.1 - 2.3e-11 43.5 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DHH family Abhydrolase_6 PF12697.2 ETS77084.1 - 3.4e-17 63.0 0.0 6.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77084.1 - 4.9e-08 32.8 0.0 1.6e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS77084.1 - 2.7e-07 30.4 0.0 5.4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 ETS77084.1 - 0.03 14.0 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GMC_oxred_N PF00732.14 ETS77085.1 - 3.8e-65 219.9 0.0 4.8e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS77085.1 - 6.6e-37 126.9 0.0 1.1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS77085.1 - 9.8e-08 31.2 1.7 1.6e-06 27.3 1.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77085.1 - 7.3e-07 28.3 0.3 0.0092 14.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS77085.1 - 1.2e-06 28.4 0.1 5.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS77085.1 - 1.6e-05 24.9 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS77085.1 - 0.00012 22.2 0.0 0.095 12.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77085.1 - 0.00024 20.1 0.1 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS77085.1 - 0.00073 18.1 0.1 0.0056 15.1 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 ETS77085.1 - 0.011 16.1 0.0 0.59 10.5 0.0 3.3 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77085.1 - 0.053 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family p450 PF00067.17 ETS77086.1 - 7.4e-58 196.1 0.0 1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS77086.1 - 2.1e-22 79.7 0.0 6.5e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SKG6 PF08693.5 ETS77086.1 - 0.077 12.3 1.5 0.14 11.4 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tmemb_185A PF10269.4 ETS77087.1 - 6.6e-05 22.6 8.6 0.008 15.7 2.5 2.2 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein DUF1218 PF06749.7 ETS77087.1 - 0.035 14.5 3.1 0.058 13.8 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF4383 PF14325.1 ETS77087.1 - 2.9 7.9 10.4 2 8.4 2.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4383) Sulfotransfer_3 PF13469.1 ETS77088.1 - 0.0017 19.3 0.5 0.0029 18.5 0.3 1.4 1 1 0 1 1 1 1 Sulfotransferase family Ribonuclease PF00545.15 ETS77089.1 - 9e-24 83.3 4.6 1.1e-11 44.6 0.1 2.7 2 2 0 2 2 2 2 ribonuclease DUF3632 PF12311.3 ETS77090.1 - 3.3e-28 98.7 0.9 4.5e-28 98.2 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) HET PF06985.6 ETS77091.1 - 2.3e-28 99.0 1.0 4.8e-28 98.0 0.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sterol_MT_C PF08498.5 ETS77092.1 - 1.1e-27 95.7 0.1 1.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 ETS77092.1 - 5.4e-21 74.8 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77092.1 - 1.1e-17 63.9 0.0 1.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS77092.1 - 6.2e-13 48.7 0.2 1.1e-12 47.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS77092.1 - 3.4e-12 46.6 0.0 6.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77092.1 - 8.9e-11 42.1 0.2 3.3e-10 40.3 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77092.1 - 1.2e-09 38.7 0.0 3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS77092.1 - 1.8e-09 37.0 0.0 2.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS77092.1 - 4.7e-09 36.2 0.1 1.5e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS77092.1 - 1.7e-08 33.9 0.1 2.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 ETS77092.1 - 0.00036 20.1 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 ETS77092.1 - 0.00057 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 ETS77092.1 - 0.0017 16.7 0.0 0.0024 16.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 ETS77092.1 - 0.0062 15.5 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 ETS77092.1 - 0.0062 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 ETS77092.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 ETS77092.1 - 0.04 14.7 0.0 0.14 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 ETS77092.1 - 0.053 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 ETS77092.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 ETS77092.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 ETS77094.1 - 0.025 14.3 0.4 0.069 12.8 0.3 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 ETS77095.1 - 3.9e-38 131.0 39.4 3.9e-38 131.0 27.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77095.1 - 3e-12 45.8 5.8 3e-12 45.8 4.0 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter LNP1 PF15419.1 ETS77096.1 - 0.016 15.3 0.2 0.032 14.3 0.2 1.4 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Cortex-I_coil PF09304.5 ETS77096.1 - 0.74 9.8 3.4 1.7 8.7 0.5 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil FTA2 PF13095.1 ETS77097.1 - 1.3e-29 103.3 0.2 7.9e-29 100.7 0.1 2.1 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 ETS77097.1 - 0.0046 16.1 0.2 0.14 11.2 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain COesterase PF00135.23 ETS77098.1 - 1.3e-77 261.7 0.0 2.3e-77 260.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77098.1 - 1.8e-05 24.4 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS77098.1 - 0.0091 15.2 0.2 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF596 PF04591.7 ETS77098.1 - 0.011 15.5 0.3 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF596 Nop14 PF04147.7 ETS77099.1 - 0.11 10.4 12.0 0.13 10.2 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETS77099.1 - 0.88 8.7 13.3 1.2 8.2 9.2 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.7 ETS77099.1 - 1.2 8.7 14.5 2.2 7.9 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 ETS77099.1 - 1.7 8.6 10.5 2.2 8.2 3.6 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 RXT2_N PF08595.6 ETS77099.1 - 2 8.2 10.0 4.1 7.1 6.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2722 PF10846.3 ETS77099.1 - 6.8 5.6 8.2 8.6 5.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HET PF06985.6 ETS77100.1 - 1.2e-31 109.7 0.1 2e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytadhesin_P30 PF07271.6 ETS77100.1 - 0.24 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 TMCO5 PF14992.1 ETS77100.1 - 3.4 6.7 3.7 6 5.9 2.6 1.3 1 0 0 1 1 1 0 TMCO5 family DUF2614 PF11023.3 ETS77100.1 - 3.9 7.3 6.7 1.1 9.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) LolA PF03548.10 ETS77103.1 - 0.066 12.8 0.1 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Mid2 PF04478.7 ETS77103.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cellulase PF00150.13 ETS77105.1 - 4.6e-35 121.1 2.4 6.3e-35 120.7 1.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 ETS77105.1 - 2.5e-18 65.6 2.7 2.5e-18 65.6 1.9 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain X2 Cas_Cas5d PF09704.5 ETS77105.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Glyco_hydro_3 PF00933.16 ETS77106.1 - 2.6e-49 167.8 0.0 5.4e-49 166.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS77106.1 - 4.6e-41 140.8 0.1 7.1e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS77106.1 - 5.4e-14 51.8 0.1 1e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_S15 PF02129.13 ETS77107.1 - 4.3e-59 200.1 0.0 5.7e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS77107.1 - 8.3e-43 146.8 0.0 1.3e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS77107.1 - 1.2e-13 51.4 0.4 2.7e-13 50.3 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77107.1 - 9.1e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS77107.1 - 1.5e-05 24.3 0.1 5.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS77107.1 - 0.00071 19.1 0.0 0.0077 15.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 ETS77107.1 - 0.00083 17.9 0.0 0.013 14.0 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 ETS77107.1 - 0.019 14.5 0.1 0.21 11.1 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 ETS77107.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2048 PF09752.4 ETS77107.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2076 PF09849.4 ETS77108.1 - 0.051 13.6 4.7 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Aa_trans PF01490.13 ETS77109.1 - 6.2e-37 127.0 37.5 7.7e-37 126.7 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2838 PF10998.3 ETS77109.1 - 0.018 14.9 1.0 0.018 14.9 0.7 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2838) Hamartin PF04388.7 ETS77110.1 - 5.6 5.5 7.5 5.7 5.4 5.2 1.0 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.4 ETS77110.1 - 6.5 4.9 9.4 7.2 4.7 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein ABC_membrane PF00664.18 ETS77111.1 - 2.2e-74 250.3 45.6 7.9e-39 133.7 11.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS77111.1 - 5.2e-63 211.4 0.0 2.4e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS77111.1 - 1.5e-14 53.7 8.3 1.4e-05 24.4 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS77111.1 - 5e-13 49.6 0.1 0.005 16.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 ETS77111.1 - 2.4e-12 46.1 0.0 3.4e-05 22.6 0.0 3.5 3 0 0 3 3 3 3 Predicted ATPase of the ABC class AAA_17 PF13207.1 ETS77111.1 - 3.6e-10 40.7 0.1 0.00053 20.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 ETS77111.1 - 1.7e-08 33.8 0.0 0.00029 20.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS77111.1 - 2.6e-08 34.0 0.1 0.012 15.6 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 ETS77111.1 - 4.3e-08 33.3 0.6 0.023 14.8 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 ETS77111.1 - 3.4e-07 29.6 0.5 0.0003 20.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS77111.1 - 2.9e-05 24.4 0.4 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS77111.1 - 2.9e-05 23.5 0.1 0.026 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 ETS77111.1 - 3e-05 23.6 0.7 0.44 10.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 ETS77111.1 - 9.5e-05 22.2 0.1 0.32 10.9 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 ETS77111.1 - 0.00011 22.4 0.0 0.46 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 ETS77111.1 - 0.00032 20.9 2.8 1.1 9.4 0.1 4.6 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS77111.1 - 0.00093 18.7 1.9 0.039 13.3 0.0 3.5 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 ETS77111.1 - 0.0015 18.2 0.3 0.94 9.1 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 ETS77111.1 - 0.0024 16.9 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 ETS77111.1 - 0.0056 16.2 0.6 0.83 9.1 0.0 3.1 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 ETS77111.1 - 0.0069 16.2 0.1 4 7.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 ETS77111.1 - 0.0089 15.7 0.0 9.9 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 ETS77111.1 - 0.01 14.5 0.0 0.37 9.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 ETS77111.1 - 0.01 15.3 0.1 3.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 ETS77111.1 - 0.013 15.4 0.3 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS77111.1 - 0.019 14.9 0.1 2.2 8.2 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 ETS77111.1 - 0.019 14.8 0.2 1 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS77111.1 - 0.062 13.4 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 ETS77111.1 - 0.16 11.7 0.9 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 ETS77111.1 - 0.17 11.5 0.6 11 5.6 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase DUF3094 PF11293.3 ETS77111.1 - 0.23 10.9 0.5 0.81 9.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) FSH1 PF03959.8 ETS77112.1 - 5.7e-31 107.6 0.0 1.7e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.21 ETS77113.1 - 5.3e-73 245.6 0.0 5.1e-72 242.3 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS77113.1 - 3.7e-60 202.6 0.2 1e-59 201.2 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 ETS77113.1 - 6.6e-57 193.2 0.0 1.1e-56 192.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS77113.1 - 4.1e-49 166.7 0.5 4.1e-49 166.7 0.3 3.2 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 ETS77113.1 - 2.4e-48 164.8 0.1 4e-48 164.1 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 ETS77113.1 - 7.7e-40 135.4 0.1 4e-39 133.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS77113.1 - 1.3e-18 66.7 0.1 7.3e-18 64.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS77113.1 - 2.5e-09 36.8 0.0 7.4e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 ETS77113.1 - 0.0018 17.2 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 ETS77113.1 - 0.0022 18.2 0.2 0.0058 16.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Deltaretro_Tax PF05599.6 ETS77114.1 - 0.048 13.9 3.1 1.7 9.0 0.4 2.1 1 1 1 2 2 2 0 Deltaretrovirus Tax protein Phytase PF02333.10 ETS77115.1 - 1.4e-53 182.0 2.8 4.6e-53 180.3 0.8 2.0 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 ETS77115.1 - 0.0011 19.1 26.5 0.1 12.7 9.8 2.5 2 0 0 2 2 2 2 EGF-like domain Radical_SAM PF04055.16 ETS77116.1 - 2e-14 54.0 0.0 5.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 ETS77116.1 - 3.5e-12 46.1 0.0 9.5e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family UQ_con PF00179.21 ETS77117.1 - 4e-43 146.1 0.0 5.6e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 ETS77117.1 - 1.7e-06 27.5 0.0 2.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 ETS77117.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS77117.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 ETS77117.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pneumo_att_G PF05539.6 ETS77118.1 - 1 8.6 7.0 1.4 8.2 4.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DOPA_dioxygen PF08883.6 ETS77119.1 - 1.2e-24 86.3 0.0 1.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family COesterase PF00135.23 ETS77120.1 - 3.2e-80 270.3 0.0 2.5e-73 247.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77120.1 - 8.5e-09 35.2 0.1 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Collagen PF01391.13 ETS77121.1 - 0.0043 16.5 1.0 0.0075 15.7 0.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ribonuclease_T2 PF00445.13 ETS77123.1 - 5.6e-34 117.4 0.0 8e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Zn_clus PF00172.13 ETS77124.1 - 6.1e-09 35.6 13.0 1.2e-08 34.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS77124.1 - 9.8e-09 34.4 7.7 2e-08 33.4 5.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain EII-GUT PF03608.8 ETS77124.1 - 0.072 12.9 0.1 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Med15 PF09606.5 ETS77124.1 - 4.8 5.2 50.3 7.8 4.5 34.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WSC PF01822.14 ETS77125.1 - 3.4e-37 126.2 22.6 6.7e-19 67.6 6.3 2.2 2 0 0 2 2 2 2 WSC domain NmrA PF05368.8 ETS77126.1 - 4e-24 85.1 0.0 6.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS77126.1 - 5e-10 39.6 0.4 1.7e-09 37.9 0.1 2.0 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS77126.1 - 5.1e-06 25.3 0.1 7.9e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETS77126.1 - 0.00029 20.5 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS77126.1 - 0.00075 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 ETS77126.1 - 0.00088 18.3 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETS77126.1 - 0.0065 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dioxygenase_C PF00775.16 ETS77127.1 - 7.7e-10 38.3 0.9 1.7e-09 37.1 0.6 1.6 1 1 0 1 1 1 1 Dioxygenase Zn_clus PF00172.13 ETS77128.1 - 1.7e-06 27.8 6.1 3.8e-06 26.6 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 ETS77129.1 - 2.4e-51 169.8 22.5 3.2e-12 45.8 0.9 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 ETS77129.1 - 4.2e-38 130.6 0.8 6e-38 130.1 0.6 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 ETS77129.1 - 3.9e-08 32.7 0.0 9.1e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 ETS77129.1 - 4.7e-05 23.1 0.0 0.0024 17.5 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETS77129.1 - 0.0002 20.2 0.4 0.31 9.7 0.1 3.7 3 1 0 3 3 3 2 Nup133 N terminal like RAB3GAP2_N PF14655.1 ETS77129.1 - 0.021 13.8 0.0 0.33 9.9 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 ETS77129.1 - 0.093 10.8 0.0 9.2 4.2 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF3639 PF12341.3 ETS77129.1 - 0.11 12.4 3.6 0.34 10.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3639) Med11 PF10280.4 ETS77130.1 - 1.5e-29 102.4 0.0 1.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Herpes_UL32 PF06070.6 ETS77130.1 - 0.038 12.4 0.3 0.037 12.5 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Secretin_N_2 PF07655.8 ETS77130.1 - 0.057 13.8 4.1 0.28 11.5 0.2 2.8 1 1 2 3 3 3 0 Secretin N-terminal domain Vps5 PF09325.5 ETS77131.1 - 4.2e-86 288.0 11.6 4.2e-86 288.0 8.1 1.9 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 ETS77131.1 - 1.2e-24 86.2 0.1 2.5e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 ETS77131.1 - 8.6e-05 21.5 3.8 0.00035 19.6 2.7 1.9 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.4 ETS77131.1 - 0.00085 18.6 2.4 0.03 13.5 1.7 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein His_Phos_2 PF00328.17 ETS77131.1 - 0.12 11.6 1.9 0.2 10.9 1.3 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 ETS77131.1 - 0.99 8.8 11.5 0.28 10.6 6.0 1.5 2 0 0 2 2 2 0 BAR domain Cortex-I_coil PF09304.5 ETS77131.1 - 4.6 7.3 10.2 3 7.9 4.1 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil Ribosomal_L31 PF01197.13 ETS77132.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 Flavin_Reduct PF01613.13 ETS77133.1 - 4e-20 72.2 0.1 4.1e-19 68.9 0.0 2.3 2 1 0 2 2 2 1 Flavin reductase like domain EspF PF04806.7 ETS77134.1 - 0.02 15.0 1.0 0.051 13.7 0.2 1.9 2 0 0 2 2 2 0 EspF protein repeat Uteroglobin PF01099.12 ETS77136.1 - 0.13 12.0 1.9 0.34 10.7 0.0 2.2 1 1 1 2 2 2 0 Uteroglobin family Arg_tRNA_synt_N PF03485.11 ETS77136.1 - 2.8 8.5 8.1 5.9 7.5 1.4 3.2 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain NUFIP2 PF15293.1 ETS77137.1 - 0.023 13.4 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 DUF4473 PF14747.1 ETS77137.1 - 0.033 14.3 0.8 0.056 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Pex14_N PF04695.8 ETS77137.1 - 3.6 7.6 5.9 0.36 10.8 0.2 2.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.13 ETS77138.1 - 1.9e-08 34.0 14.4 3.7e-08 33.1 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS77139.1 - 1.8e-18 66.3 0.7 2.5e-18 65.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77139.1 - 1.5e-06 27.9 11.3 3e-06 27.0 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 ETS77140.1 - 2.6e-74 249.3 0.0 3.2e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS77140.1 - 0.0055 16.7 0.4 0.27 11.1 0.3 2.2 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 ETS77140.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2498) Dynamin_M PF01031.15 ETS77141.1 - 6e-106 353.5 0.0 6e-106 353.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 ETS77141.1 - 1.9e-55 187.1 0.0 3.8e-55 186.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 ETS77141.1 - 1.6e-29 101.6 9.6 2.9e-29 100.7 5.1 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS77141.1 - 0.00016 21.5 0.3 0.004 17.0 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS77141.1 - 0.015 15.7 0.0 0.04 14.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 ETS77142.1 - 5.8e-31 105.2 16.6 2.1e-08 33.7 0.2 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETS77142.1 - 0.00083 18.2 0.0 0.95 8.1 0.0 2.5 1 1 1 2 2 2 2 Coatomer WD associated region CLTH PF10607.4 ETS77142.1 - 0.0057 16.3 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain AMP-binding PF00501.23 ETS77143.1 - 2e-49 168.1 0.0 2.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS77143.1 - 0.0042 17.9 0.0 0.0079 17.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_2 PF00797.12 ETS77144.1 - 3.7e-34 118.3 0.3 2.6e-33 115.5 0.2 2.1 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 ETS77144.1 - 0.0068 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core2 PF13369.1 ETS77144.1 - 0.01 15.3 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily Acetyltransf_3 PF13302.1 ETS77145.1 - 5.6e-12 46.0 0.0 9.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS77145.1 - 0.00051 20.0 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS77145.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS77145.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 ETS77146.1 - 3.6e-10 39.4 0.5 5.8e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 ETS77146.1 - 0.001 17.6 0.4 0.019 13.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS77146.1 - 0.022 13.6 0.3 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77146.1 - 0.023 13.5 0.4 0.038 12.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 ETS77146.1 - 0.053 12.5 0.1 0.082 11.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS77146.1 - 0.067 12.0 0.3 5 5.9 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 ETS77146.1 - 0.17 10.9 0.0 0.74 8.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Abhydrolase_6 PF12697.2 ETS77147.1 - 3e-26 92.7 0.0 3.9e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77147.1 - 2e-15 56.9 0.0 7.5e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS77147.1 - 8.6e-14 51.5 0.0 2.2e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS77147.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS77147.1 - 0.1 11.8 0.0 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETS77147.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) HET PF06985.6 ETS77148.1 - 2.5e-21 76.3 0.1 1.1e-20 74.1 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nop14 PF04147.7 ETS77148.1 - 2.6 5.8 9.0 3.7 5.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS77148.1 - 5.7 4.8 6.1 8.2 4.3 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 ETS77149.1 - 1.1e-38 131.3 3.0 2.9e-18 65.9 0.1 6.4 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77149.1 - 2.7e-27 93.1 15.2 3.6e-07 29.6 0.1 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 ETS77149.1 - 1.1e-24 86.3 16.8 4.5e-10 39.7 0.0 9.4 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77149.1 - 7.4e-23 78.3 7.0 0.00018 21.4 0.0 9.0 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 ETS77149.1 - 2e-18 66.0 11.6 0.012 15.8 0.1 9.4 9 2 1 10 10 10 4 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS77149.1 - 3.9e-16 58.6 1.7 9.9e-16 57.3 1.1 1.8 1 0 0 1 1 1 1 Clr5 domain DUF2264 PF10022.4 ETS77150.1 - 1.4e-127 425.3 0.0 1.7e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 ETS77150.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat Aminotran_5 PF00266.14 ETS77151.1 - 7.1e-33 113.8 0.0 1.5e-21 76.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V adh_short PF00106.20 ETS77152.1 - 2.5e-09 37.2 0.0 5.2e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS77152.1 - 7.8e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS77152.1 - 0.00041 20.0 0.0 0.0012 18.5 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS77152.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TRAPPC9-Trs120 PF08626.6 ETS77153.1 - 1.3e-139 466.6 0.0 1.3e-138 463.3 0.0 2.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Longin PF13774.1 ETS77154.1 - 1.7e-26 91.5 0.1 2.6e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETS77154.1 - 3.5e-15 55.3 0.1 7.1e-15 54.3 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 ETS77154.1 - 0.0058 16.4 0.3 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) KIP1 PF07765.7 ETS77154.1 - 0.25 11.2 1.2 9.7 6.1 0.1 2.3 2 0 0 2 2 2 0 KIP1-like protein ASXH PF13919.1 ETS77155.1 - 3.6e-08 33.2 4.1 8.5e-07 28.8 2.8 2.5 1 1 0 1 1 1 1 Asx homology domain TraG_N PF07916.6 ETS77155.1 - 0.14 10.6 0.7 0.15 10.4 0.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Asp PF00026.18 ETS77156.1 - 9.3e-50 169.6 0.1 1.2e-49 169.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 ETS77156.1 - 4e-07 29.7 0.1 0.00047 19.7 0.0 3.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 ETS77156.1 - 1.2e-05 25.7 0.6 0.36 11.3 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 ETS77156.1 - 0.059 13.2 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Elong_Iki1 PF10483.4 ETS77157.1 - 2.1e-78 263.5 0.0 2.6e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 DHHA1 PF02272.14 ETS77157.1 - 0.029 14.0 1.1 0.063 12.9 0.8 1.5 1 0 0 1 1 1 0 DHHA1 domain Proteasome PF00227.21 ETS77158.1 - 3.3e-53 179.8 0.1 4.2e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS77158.1 - 3e-11 42.4 0.2 4.7e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 ETS77159.1 - 6.8e-46 154.9 7.2 7.5e-46 154.7 5.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Lysine_decarbox PF03641.9 ETS77160.1 - 7.1e-31 106.7 0.1 9.5e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase PAM2 PF07145.10 ETS77160.1 - 0.13 11.7 0.6 0.26 10.8 0.4 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region CLPTM1 PF05602.7 ETS77161.1 - 1.8e-159 531.1 0.0 2.2e-159 530.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PAS_9 PF13426.1 ETS77163.1 - 7.1e-20 71.3 0.0 9.6e-17 61.2 0.0 2.8 3 0 0 3 3 3 2 PAS domain GldM_N PF12081.3 ETS77164.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Acetyltransf_1 PF00583.19 ETS77165.1 - 2.7e-16 59.3 0.0 3.7e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS77165.1 - 8.6e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS77165.1 - 1.5e-08 34.6 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS77165.1 - 2.1e-05 24.2 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETS77165.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS77165.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1793 PF08760.6 ETS77166.1 - 8.9e-71 237.2 0.8 8.9e-71 237.2 0.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) Glyco_hydro_47 PF01532.15 ETS77169.1 - 6.5e-163 542.5 0.0 7.5e-163 542.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.17 ETS77170.1 - 1e-19 69.9 0.0 1.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS77170.1 - 3e-16 59.1 0.0 4.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS77170.1 - 2.3e-11 43.3 0.0 3.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.16 ETS77172.1 - 1.6e-06 28.6 0.1 3.3e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETS77172.1 - 0.00032 20.6 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DB PF01682.14 ETS77173.1 - 0.013 15.4 0.7 4.6 7.3 0.1 2.3 2 0 0 2 2 2 0 DB module DUF1993 PF09351.5 ETS77173.1 - 0.15 11.9 1.7 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Ank_2 PF12796.2 ETS77174.1 - 5.6e-17 61.8 0.6 1.1e-09 38.5 0.0 4.6 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77174.1 - 2.6e-12 45.8 1.7 0.0039 16.9 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 ETS77174.1 - 1.2e-09 38.0 0.4 0.0021 18.2 0.1 3.9 4 0 0 4 4 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS77174.1 - 1.2e-09 38.4 1.5 8.3e-06 26.1 0.2 4.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.7 ETS77174.1 - 6.5e-09 35.6 0.0 1.5e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS77174.1 - 4.9e-08 33.1 0.0 2.6e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 ETS77174.1 - 3e-06 26.9 1.6 0.32 11.3 0.0 4.9 5 0 0 5 5 3 2 Ankyrin repeat AAA_22 PF13401.1 ETS77174.1 - 9.3e-05 22.5 0.0 0.00049 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS77174.1 - 0.0051 17.1 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 ETS77174.1 - 0.0078 15.6 0.8 0.071 12.5 0.6 2.5 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 ETS77174.1 - 0.0079 16.3 0.1 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.9 ETS77174.1 - 0.015 14.3 3.0 1.9 7.3 0.3 2.5 1 1 0 2 2 2 0 KAP family P-loop domain KaiC PF06745.8 ETS77174.1 - 0.035 13.2 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC ATP_bind_1 PF03029.12 ETS77174.1 - 0.055 12.9 0.2 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 ETS77174.1 - 0.056 12.4 0.2 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 ETS77174.1 - 0.079 12.8 0.1 0.47 10.3 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 ETS77174.1 - 0.094 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS77174.1 - 0.11 13.3 0.1 0.85 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS77174.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 ETS77174.1 - 0.13 11.5 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Amino_oxidase PF01593.19 ETS77175.1 - 5.6e-16 58.6 0.1 1.1e-12 47.8 0.1 2.6 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS77175.1 - 0.006 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 ETS77176.1 - 1.3e-24 86.3 0.7 3.6e-18 65.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77176.1 - 1.9e-16 58.9 2.5 4.5e-05 23.0 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETS77176.1 - 9.1e-12 44.8 0.1 0.004 17.3 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS77176.1 - 6.8e-11 42.3 0.2 2e-05 24.9 0.1 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77176.1 - 2.6e-08 33.3 0.1 0.25 11.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Methyltransf_23 PF13489.1 ETS77177.1 - 3.6e-08 33.2 0.0 7.5e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77177.1 - 4e-05 23.2 0.0 0.00035 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77177.1 - 0.0021 18.5 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77177.1 - 0.0028 18.0 0.0 0.0077 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77177.1 - 0.072 13.6 0.0 0.43 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETS77177.1 - 0.098 12.6 0.0 0.69 9.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 ETS77178.1 - 5.2e-30 104.3 29.5 5.2e-30 104.3 20.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 ETS77179.1 - 6e-37 127.7 0.0 7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 ETS77179.1 - 0.021 15.3 0.1 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Tautomerase_3 PF14832.1 ETS77180.1 - 2.7e-42 144.0 0.0 3.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme 4HBT_3 PF13622.1 ETS77181.1 - 2.5e-37 129.0 0.5 2.9e-37 128.7 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 ETS77181.1 - 0.0022 17.6 0.0 0.0072 15.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA thioesterase Lactamase_B PF00753.22 ETS77182.1 - 2.8e-21 76.0 0.0 4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS77182.1 - 2.1e-09 37.2 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS77182.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.27 ETS77183.1 - 1.2e-42 142.3 25.0 4.3e-12 45.4 0.6 9.7 10 0 0 10 10 10 6 WD domain, G-beta repeat NACHT PF05729.7 ETS77183.1 - 1.1e-22 80.4 0.1 2.4e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETS77183.1 - 1.5e-06 27.7 1.7 0.51 10.0 0.0 5.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 ETS77183.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 ETS77183.1 - 0.048 13.8 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS77183.1 - 0.15 11.7 0.0 0.74 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Proteasome_A_N PF10584.4 ETS77183.1 - 5.1 6.5 11.4 21 4.5 0.0 4.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF1986 PF09342.6 ETS77184.1 - 0.099 11.9 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ndufs5 PF10200.4 ETS77186.1 - 0.00034 20.5 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 ETS77186.1 - 0.05 13.6 0.2 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 ETS77186.1 - 0.11 12.5 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 ETS77186.1 - 0.12 12.5 0.4 0.21 11.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Sec39 PF08314.6 ETS77187.1 - 8.5e-219 728.1 0.5 1e-218 727.8 0.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF1996 PF09362.5 ETS77189.1 - 2.8e-77 259.5 0.2 2.8e-77 259.5 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 ETS77190.1 - 1.6e-08 34.0 0.0 3.1e-07 29.9 0.0 2.9 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 ETS77190.1 - 7.8e-08 31.9 0.1 5.5e-07 29.2 0.0 2.5 3 0 0 3 3 3 1 UBA/TS-N domain TPR_2 PF07719.12 ETS77190.1 - 0.00014 21.5 0.0 3.4 7.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS77190.1 - 0.0024 17.4 0.1 4.6 7.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS77190.1 - 0.01 15.7 0.8 0.058 13.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 ETS77190.1 - 0.017 14.8 1.0 0.033 13.9 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain Sugar_tr PF00083.19 ETS77192.1 - 4.1e-111 371.7 19.5 4.7e-111 371.5 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77192.1 - 4e-23 81.6 27.1 1e-15 57.3 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 ETS77192.1 - 0.0062 14.6 2.2 0.014 13.4 1.5 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UQ_con PF00179.21 ETS77193.1 - 3.7e-51 172.2 0.0 4.1e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_11 PF13414.1 ETS77194.1 - 2.8e-05 23.6 12.7 0.0026 17.3 0.5 4.2 4 2 1 5 5 5 2 TPR repeat TPR_17 PF13431.1 ETS77194.1 - 3.6e-05 23.6 0.7 0.031 14.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS77194.1 - 0.00012 22.6 13.0 0.0061 17.2 0.7 4.2 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS77194.1 - 0.041 13.4 0.1 2.2 7.9 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS77194.1 - 0.092 13.4 10.8 2.1 9.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS77194.1 - 0.1 12.5 4.7 7.3 6.7 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.6 ETS77195.1 - 9.8e-31 106.7 2.9 2e-30 105.7 2.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 ETS77196.1 - 2.2e-16 59.8 0.1 3.8e-16 59.0 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS77196.1 - 3.4e-14 53.2 0.1 4.5e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS77196.1 - 1.7e-07 30.9 0.4 5.9e-07 29.1 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS77196.1 - 0.0025 17.7 0.7 0.0052 16.7 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 ETS77196.1 - 0.0059 17.0 0.5 0.032 14.6 0.0 2.2 1 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 ETS77196.1 - 0.0079 15.8 0.2 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 ETS77198.1 - 4.5e-23 81.5 45.1 1.4e-12 47.0 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 ETS77200.1 - 6.5e-46 156.6 3.7 9.8e-46 156.0 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 ETS77200.1 - 4.2e-16 59.3 0.0 2e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.13 ETS77200.1 - 2e-07 30.7 7.8 4e-07 29.8 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 ETS77200.1 - 0.0014 18.7 0.4 0.019 15.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS77200.1 - 0.0032 17.1 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS77200.1 - 0.006 16.5 3.7 0.02 14.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS77200.1 - 0.031 14.0 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 ETS77200.1 - 0.2 11.2 0.1 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1349 PF07081.6 ETS77201.1 - 9.5e-20 70.7 0.0 1.8e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Voldacs PF03517.8 ETS77203.1 - 2.5e-26 92.1 0.1 4.9e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling SpoVR PF04293.8 ETS77204.1 - 0.17 10.2 0.1 0.21 9.9 0.1 1.0 1 0 0 1 1 1 0 SpoVR like protein GST_C_2 PF13410.1 ETS77204.1 - 0.4 10.6 5.6 1 9.2 3.9 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EXS PF03124.9 ETS77205.1 - 2.4e-95 319.5 29.0 2.9e-95 319.2 20.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 ETS77205.1 - 3.1e-57 194.4 1.7 4.4e-57 193.9 0.0 2.0 2 0 0 2 2 2 1 SPX domain Glyco_hydro_18 PF00704.23 ETS77206.1 - 9.3e-11 41.7 0.0 1.7e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MS_channel PF00924.13 ETS77207.1 - 1.4e-21 76.7 1.4 2.4e-21 76.0 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Acyl-CoA_dh_C PF12806.2 ETS77207.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like EF-hand_7 PF13499.1 ETS77207.1 - 0.034 14.2 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 ETS77207.1 - 0.038 13.8 0.2 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 ETS77207.1 - 0.17 11.2 1.2 0.43 9.9 0.8 1.7 1 0 0 1 1 1 0 EF hand zf-DHHC PF01529.15 ETS77209.1 - 7.2e-42 142.7 10.5 1.3e-41 141.8 7.3 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 ETS77209.1 - 6.6 6.6 13.7 0.13 12.0 4.5 1.9 2 0 0 2 2 2 0 Double zinc ribbon PI-PLC-X PF00388.14 ETS77211.1 - 8.5e-54 180.9 0.0 1.6e-53 180.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS77211.1 - 7.1e-38 129.2 0.9 1.3e-37 128.4 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 ETS77211.1 - 3.8e-08 33.0 0.1 1.2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 C2 domain PH PF00169.24 ETS77211.1 - 0.014 15.6 0.2 0.033 14.3 0.1 1.7 1 0 0 1 1 1 0 PH domain Peptidase_S15 PF02129.13 ETS77212.1 - 1.1e-39 136.5 4.2 3.9e-37 128.1 1.1 2.8 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS77212.1 - 4.3e-22 79.0 1.3 3.1e-21 76.2 0.9 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 ETS77213.1 - 1.1e-37 129.9 0.0 1.5e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS77213.1 - 5.3e-29 101.6 0.0 8.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS77213.1 - 2.4e-07 30.8 0.4 5e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77213.1 - 2.7e-06 27.1 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 ETS77213.1 - 0.034 13.6 0.1 0.066 12.6 0.1 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain Zn_clus PF00172.13 ETS77214.1 - 4.5e-08 32.8 12.0 9.7e-08 31.8 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 ETS77215.1 - 1.9e-38 132.5 0.1 7.4e-38 130.6 0.1 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 ETS77216.1 - 2.7e-48 164.8 0.1 4e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ACT_3 PF10000.4 ETS77217.1 - 5.5e-18 64.4 0.0 8.8e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 ETS77217.1 - 5.5e-10 38.6 0.0 1.8e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 ACT domain Ank_2 PF12796.2 ETS77218.1 - 2.7e-51 171.8 4.7 1.4e-16 60.6 0.0 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77218.1 - 7e-45 148.6 6.3 6.5e-06 25.6 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 ETS77218.1 - 8.1e-35 118.5 9.4 1.4e-10 41.3 0.1 7.9 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77218.1 - 1.1e-27 95.4 13.0 8e-09 35.4 0.7 7.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77218.1 - 8e-27 90.6 4.4 0.00026 20.9 0.0 9.8 9 1 0 9 9 9 6 Ankyrin repeat CorA PF01544.13 ETS77218.1 - 1.2e-12 47.5 3.4 2e-12 46.7 1.4 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Claudin_2 PF13903.1 ETS77218.1 - 0.045 13.4 0.2 0.088 12.4 0.1 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TadE PF07811.7 ETS77218.1 - 4.5 7.2 7.3 8.1 6.4 1.2 2.7 2 0 0 2 2 2 0 TadE-like protein Fungal_trans PF04082.13 ETS77220.1 - 2.2e-22 79.1 1.1 4.1e-22 78.3 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77220.1 - 7.6e-09 35.3 9.9 2e-08 33.9 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 ETS77221.1 - 1.2e-31 109.8 1.2 1.7e-31 109.3 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS77221.1 - 2.6e-18 65.2 0.6 6.1e-18 64.0 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS77221.1 - 1.8e-15 57.4 0.0 4.9e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS77221.1 - 1.2e-06 28.8 0.6 1.8e-06 28.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.12 ETS77222.1 - 7.2e-66 221.4 0.0 1.4e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS77222.1 - 1.5e-36 124.8 0.0 7.8e-36 122.5 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS77222.1 - 3.1e-31 107.5 0.0 6.1e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 ETS77222.1 - 7.9e-15 55.0 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 ETS77222.1 - 2.4e-10 39.9 1.7 5.5e-10 38.7 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 ETS77222.1 - 8.5e-10 37.8 0.0 5.8e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ETS77222.1 - 3.8e-08 32.8 0.0 8.5e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS77222.1 - 3.7e-07 29.7 0.0 1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 ETS77222.1 - 1.5e-06 28.1 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.14 ETS77222.1 - 0.056 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Carboxyl_trans PF01039.17 ETS77223.1 - 2.5e-117 392.2 0.0 3.1e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.23 ETS77224.1 - 1.6e-93 313.3 0.0 1.9e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS77224.1 - 6.1e-12 46.3 0.0 1.3e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DRTGG PF07085.7 ETS77224.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 DRTGG domain HMGL-like PF00682.14 ETS77225.1 - 9.6e-40 136.7 0.0 1.3e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 ETS77225.1 - 6.6e-38 130.2 0.0 1.5e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4313 PF14190.1 ETS77226.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) DUF3405 PF11885.3 ETS77227.1 - 6.1e-75 252.3 1.0 9.1e-75 251.7 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Arabino_trans_C PF14896.1 ETS77227.1 - 0.015 13.9 0.1 0.02 13.4 0.0 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain SKG6 PF08693.5 ETS77228.1 - 0.031 13.5 0.2 0.076 12.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UbiD PF01977.11 ETS77229.1 - 8e-121 403.3 0.0 1e-120 402.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 ETS77230.1 - 2.9e-25 88.4 0.1 4.1e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein GNVR PF13807.1 ETS77230.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase MNHE PF01899.11 ETS77230.1 - 0.048 13.3 0.1 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit ABC_membrane PF00664.18 ETS77231.1 - 2.5e-45 155.0 10.6 3.3e-45 154.6 7.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 ETS77231.1 - 4.1e-34 117.8 0.0 7.8e-33 113.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 ETS77231.1 - 4.9e-06 25.9 0.1 0.00024 20.3 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS77231.1 - 0.00013 21.9 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 ETS77231.1 - 0.00024 21.1 2.9 0.21 11.5 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS77231.1 - 0.00069 20.4 0.0 0.0016 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS77231.1 - 0.0015 18.6 0.3 0.035 14.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS77231.1 - 0.0031 17.2 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETS77231.1 - 0.0053 16.9 0.6 0.07 13.3 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETS77231.1 - 0.012 15.0 0.2 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 ETS77231.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 ETS77231.1 - 0.023 13.2 0.7 0.035 12.7 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 ETS77231.1 - 0.026 14.4 0.6 0.37 10.7 0.3 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 ETS77231.1 - 0.037 13.9 0.0 0.23 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 ETS77231.1 - 0.049 13.0 0.2 0.23 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS77231.1 - 0.072 13.3 0.1 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PBP_sp32 PF07222.7 ETS77231.1 - 0.35 10.0 2.9 0.75 8.9 2.0 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Abhydrolase_6 PF12697.2 ETS77232.1 - 6.3e-20 72.0 0.3 7.9e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS77232.1 - 3.2e-19 68.5 0.0 1.1e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 ETS77232.1 - 7.5e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77232.1 - 4.3e-06 26.4 0.0 6.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS77232.1 - 0.0031 17.1 0.0 0.0098 15.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Peptidase_S9 PF00326.16 ETS77232.1 - 0.012 14.8 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.8 ETS77232.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 ETS77232.1 - 0.077 13.2 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.2 ETS77232.1 - 0.11 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Adaptin_N PF01602.15 ETS77233.1 - 5.7e-145 483.6 5.9 6.7e-145 483.3 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 ETS77233.1 - 1.6e-19 70.2 0.0 4.1e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 ETS77233.1 - 0.00013 22.1 0.7 1.4 9.2 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 ETS77233.1 - 0.021 15.3 1.4 5.9 7.5 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat RIX1 PF08167.7 ETS77233.1 - 0.032 13.8 0.0 0.36 10.4 0.0 2.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF4297 PF14130.1 ETS77233.1 - 0.046 13.6 0.3 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) HEAT PF02985.17 ETS77233.1 - 0.066 13.3 2.2 28 5.1 0.1 4.4 4 1 1 5 5 5 0 HEAT repeat TIP120 PF08623.5 ETS77233.1 - 0.092 12.3 3.4 0.18 11.3 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 ETS77233.1 - 0.11 12.3 8.5 0.3 10.8 1.4 3.8 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 ETS77233.1 - 0.13 12.0 2.1 1e+02 2.9 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat WW PF00397.21 ETS77235.1 - 0.046 13.5 0.9 0.1 12.5 0.6 1.6 1 0 0 1 1 1 0 WW domain Orn_Arg_deC_N PF02784.11 ETS77236.1 - 9.4e-79 264.1 0.0 1.3e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 ETS77236.1 - 6.3e-30 103.2 0.0 2.5e-29 101.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 ETS77236.1 - 0.029 13.6 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel M16C_assoc PF08367.6 ETS77237.1 - 1.1e-57 194.8 0.1 1.7e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 ETS77237.1 - 4.3e-37 127.5 0.0 3.2e-21 75.8 0.0 3.2 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS77237.1 - 9.7e-08 31.8 0.0 1e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 ETS77238.1 - 7.3e-64 215.7 66.7 1.2e-41 142.7 29.0 3.5 2 1 1 3 3 3 2 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.4 ETS77238.1 - 0.00038 20.3 6.4 0.00038 20.3 4.5 4.2 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 ETS77238.1 - 0.0007 19.3 53.2 0.012 15.3 7.9 4.9 3 1 2 5 5 5 4 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 ETS77238.1 - 0.0028 16.2 12.3 0.0028 16.2 8.5 2.1 2 0 0 2 2 2 2 AAA domain Spc7 PF08317.6 ETS77238.1 - 0.0041 15.8 9.8 0.0041 15.8 6.8 3.8 1 1 2 3 3 3 1 Spc7 kinetochore protein APG6 PF04111.7 ETS77238.1 - 0.65 8.9 50.8 0.054 12.5 3.6 3.6 3 1 0 3 3 3 0 Autophagy protein Apg6 LTV PF04180.9 ETS77239.1 - 4e-95 319.8 15.9 4.6e-95 319.6 11.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 ETS77240.1 - 4.7e-17 62.0 0.5 2e-15 56.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS77240.1 - 1.6e-06 27.4 0.6 1.7e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 ETS77240.1 - 0.00022 20.4 0.0 0.00049 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 ETS77240.1 - 0.0067 15.5 0.1 0.014 14.5 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 ETS77240.1 - 0.021 15.3 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 ETS77240.1 - 0.026 14.3 0.1 0.026 14.3 0.0 2.7 3 0 0 3 3 3 0 Dynamin family TEX19 PF15553.1 ETS77240.1 - 2.8 7.7 6.3 9.6 6.0 4.4 1.9 1 0 0 1 1 1 0 Testis-expressed protein 19 Peptidase_S9 PF00326.16 ETS77241.1 - 1e-45 155.6 0.0 1.4e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS77241.1 - 5.1e-12 45.7 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS77241.1 - 2.1e-10 40.8 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 ETS77241.1 - 3.7e-08 32.8 2.2 0.0038 16.8 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.13 ETS77241.1 - 8.4e-08 31.7 0.0 2.9e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 ETS77241.1 - 6.7e-07 29.2 0.0 3.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 ETS77241.1 - 1.1e-06 28.4 0.0 0.0053 16.3 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETS77241.1 - 4.1e-06 26.4 0.1 0.0028 17.1 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 ETS77241.1 - 3.4e-05 23.4 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 ETS77241.1 - 0.00021 19.9 0.0 0.0024 16.4 0.0 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 ETS77241.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 ETS77241.1 - 0.0042 16.3 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.4 ETS77241.1 - 0.0079 15.4 0.1 0.023 13.9 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_M14 PF00246.19 ETS77241.1 - 0.008 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase FSH1 PF03959.8 ETS77241.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 ETS77241.1 - 0.019 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DUF1749 PF08538.5 ETS77241.1 - 0.035 13.0 0.0 0.66 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) HET PF06985.6 ETS77243.1 - 1.6e-24 86.6 0.0 3.3e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UNC-93 PF05978.11 ETS77246.1 - 1.2e-12 47.5 1.6 1.2e-12 47.5 1.1 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 ETS77246.1 - 1.1e-11 44.1 29.8 1.1e-11 44.1 20.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily LSM PF01423.17 ETS77247.1 - 1.3e-14 53.5 0.2 1.6e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS77247.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain tRNA-synt_1b PF00579.20 ETS77248.1 - 5.2e-18 65.1 0.2 1e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) 2-Hacid_dh_C PF02826.14 ETS77250.1 - 3.1e-44 150.2 0.1 3e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS77250.1 - 0.0039 17.2 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_2 PF03446.10 ETS77250.1 - 0.0066 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ETS77250.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS77250.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 ETS77250.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent tRNA-synt_1e PF01406.14 ETS77252.1 - 2.5e-114 381.4 0.0 3.9e-114 380.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 ETS77252.1 - 4e-07 29.0 1.1 0.028 13.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 ETS77252.1 - 0.0045 15.7 0.1 1 7.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 ETS77252.1 - 0.034 12.7 0.0 0.089 11.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Oxidored_FMN PF00724.15 ETS77253.1 - 2.7e-88 296.2 0.0 3.1e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NmrA PF05368.8 ETS77254.1 - 5.5e-13 48.7 0.0 7.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS77254.1 - 1.3e-11 44.7 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS77254.1 - 0.0044 15.7 0.2 0.0082 14.8 0.2 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 ETS77254.1 - 0.0062 15.5 0.0 0.0093 14.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETS77254.1 - 0.0084 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Esterase_phd PF10503.4 ETS77255.1 - 2.4e-17 62.9 0.8 3.4e-17 62.4 0.6 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS77255.1 - 1.4e-10 40.8 1.1 1.9e-10 40.3 0.6 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 ETS77255.1 - 1.2e-07 31.4 1.2 1.6e-07 31.0 0.8 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETS77255.1 - 6.1e-07 29.3 0.2 8.4e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS77255.1 - 0.003 17.1 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 ETS77255.1 - 0.13 11.7 1.7 0.2 11.1 1.2 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PEP_mutase PF13714.1 ETS77256.1 - 5.6e-55 186.1 0.5 7e-55 185.8 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETS77256.1 - 2.6e-13 49.0 0.1 3.9e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 ETS77256.1 - 0.00056 19.1 0.0 0.0062 15.6 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DAHP_synth_1 PF00793.15 ETS77256.1 - 0.046 12.4 0.0 0.1 11.2 0.0 1.5 1 0 0 1 1 1 0 DAHP synthetase I family Pyr_redox_3 PF13738.1 ETS77257.1 - 2.5e-28 99.5 0.1 3.9e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS77257.1 - 3.1e-13 48.8 0.0 4.8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS77257.1 - 1.2e-08 34.8 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS77257.1 - 5.4e-07 28.8 0.0 3.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS77257.1 - 1.1e-06 28.6 0.0 4.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS77257.1 - 3.4e-06 26.3 0.1 0.077 12.0 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 ETS77257.1 - 3.8e-06 26.0 0.0 8e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 ETS77257.1 - 0.00069 18.8 2.0 0.0031 16.6 1.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77257.1 - 0.0012 17.7 0.0 0.0031 16.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS77257.1 - 0.0021 17.0 2.3 0.22 10.3 0.3 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS77257.1 - 0.0074 15.4 1.3 0.012 14.7 0.1 2.0 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 ETS77257.1 - 0.012 14.5 0.3 0.22 10.3 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS77257.1 - 0.021 14.6 0.7 0.021 14.6 0.5 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS77257.1 - 0.05 12.7 0.4 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 ETS77257.1 - 0.18 10.2 0.8 0.54 8.6 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 ETS77258.1 - 6.8e-32 110.8 0.0 1.7e-31 109.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS77258.1 - 5.5e-09 35.3 0.4 9.6e-05 21.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS77258.1 - 4.1e-08 32.7 0.6 0.0072 15.4 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS77258.1 - 1.7e-05 24.7 0.2 4.7e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS77258.1 - 0.00033 19.8 0.0 0.00073 18.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS77258.1 - 0.00048 20.2 0.7 0.0031 17.5 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77258.1 - 0.00048 19.1 0.7 0.33 9.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS77258.1 - 0.00052 18.9 0.2 0.00088 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS77258.1 - 0.00093 19.5 0.6 0.0054 17.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77258.1 - 0.00096 19.0 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS77258.1 - 0.0023 16.4 0.2 0.013 13.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 ETS77258.1 - 0.0035 17.5 0.0 0.0095 16.1 0.0 1.8 2 0 0 2 2 1 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 ETS77258.1 - 0.006 15.2 0.0 0.0086 14.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 ETS77258.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS77258.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 ETS77258.1 - 0.084 11.6 0.0 0.68 8.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase XdhC_C PF13478.1 ETS77258.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 ETS77258.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 ETS77258.1 - 0.17 11.6 1.5 9.5 5.9 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 ETS77258.1 - 0.18 10.8 0.6 0.4 9.6 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase COesterase PF00135.23 ETS77259.1 - 7e-93 312.1 0.7 1.3e-92 311.2 0.5 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77259.1 - 0.00032 20.3 0.6 0.0013 18.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS77259.1 - 0.0009 19.0 0.2 0.0028 17.4 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tannase PF07519.6 ETS77261.1 - 3.4e-90 303.0 2.4 4.4e-90 302.6 1.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 ETS77261.1 - 0.0029 17.3 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2733 PF10813.3 ETS77261.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) FSH1 PF03959.8 ETS77261.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Clr5 PF14420.1 ETS77263.1 - 4.4e-09 36.1 0.1 5.8e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Clr5 domain Methyltransf_2 PF00891.13 ETS77264.1 - 5.4e-30 104.3 0.0 1.3e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase HET PF06985.6 ETS77265.1 - 2.3e-24 86.1 1.5 3.6e-23 82.2 1.1 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhoPQ_related PF10142.4 ETS77266.1 - 0.0014 17.1 0.1 0.0026 16.2 0.1 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 ETS77266.1 - 0.012 14.1 0.1 0.12 10.9 0.1 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4206 PF13901.1 ETS77267.1 - 0.0013 18.3 0.2 0.0027 17.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) Citrate_synt PF00285.16 ETS77267.1 - 0.1 11.3 0.2 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Citrate synthase SGL PF08450.7 ETS77268.1 - 1.4e-06 27.8 0.0 0.00075 18.9 0.0 3.0 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 ETS77268.1 - 0.0048 16.6 0.2 0.019 14.7 0.1 2.1 1 0 0 1 1 1 1 Beta-propeller repeat DIM PF08194.7 ETS77268.1 - 0.032 14.1 0.7 0.07 13.0 0.5 1.6 1 0 0 1 1 1 0 DIM protein NHL PF01436.16 ETS77268.1 - 0.19 11.7 9.9 21 5.2 0.0 4.6 5 1 0 5 5 5 0 NHL repeat Cu_amine_oxid PF01179.15 ETS77269.1 - 2.7e-162 540.2 0.0 3.3e-162 539.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS77269.1 - 0.00018 21.4 0.0 0.00068 19.6 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Aa_trans PF01490.13 ETS77270.1 - 1e-24 86.8 32.4 1.2e-24 86.6 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 ETS77270.1 - 3.5e-06 25.6 17.5 3.5e-06 25.6 12.1 2.3 1 1 0 2 2 2 1 Amino acid permease Myb_DNA-bind_6 PF13921.1 ETS77271.1 - 5.2e-31 106.5 2.8 3.7e-13 49.3 0.1 4.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS77271.1 - 3.6e-30 103.7 2.5 1.2e-11 44.4 0.1 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 ETS77271.1 - 0.012 15.5 0.1 4.1 7.3 0.0 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NmrA PF05368.8 ETS77272.1 - 0.00087 18.6 0.0 0.00088 18.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS77272.1 - 0.017 14.5 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS77272.1 - 0.021 14.8 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 ETS77272.1 - 0.14 10.8 0.1 0.15 10.6 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FmdA_AmdA PF03069.10 ETS77273.1 - 2.5e-99 332.4 0.0 2.9e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family CorA PF01544.13 ETS77276.1 - 7.3e-06 25.2 0.2 1.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0104 PF03706.8 ETS77276.1 - 0.0076 15.5 0.8 0.012 14.8 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) SH3BP5 PF05276.9 ETS77276.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Ank_2 PF12796.2 ETS77277.1 - 8.4e-164 532.4 7.6 5.3e-25 87.5 0.0 11.7 4 3 8 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77277.1 - 1.5e-152 488.4 6.9 1.4e-07 30.9 0.0 23.3 23 0 0 23 23 23 22 Ankyrin repeat Ank_3 PF13606.1 ETS77277.1 - 1.7e-117 371.3 4.1 4.9e-06 26.2 0.0 23.4 23 1 1 24 24 24 20 Ankyrin repeat Ank_4 PF13637.1 ETS77277.1 - 3.9e-111 361.7 5.1 9.2e-13 48.3 0.0 17.3 7 4 10 18 18 18 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77277.1 - 7e-102 331.1 5.9 5.8e-08 32.7 0.0 20.6 3 3 18 21 21 21 20 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 ETS77277.1 - 6e-06 25.9 0.1 10 5.5 0.0 7.6 6 4 3 9 9 9 1 Shigella flexneri OspC protein Rbsn PF11464.3 ETS77277.1 - 0.052 13.1 0.0 2 8.0 0.0 3.5 3 0 0 3 3 3 0 Rabenosyn Rab binding domain CholecysA-Rec_N PF09193.5 ETS77277.1 - 0.3 10.9 1.0 3.7 7.4 0.0 3.4 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal Macoilin PF09726.4 ETS77278.1 - 1.3 7.2 7.3 1.5 6.9 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 ETS77278.1 - 1.7 6.5 26.2 2.5 5.9 18.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.6 ETS77278.1 - 5.2 6.8 25.3 0.2 11.4 13.4 1.6 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Beta-lactamase PF00144.19 ETS77279.1 - 2.4e-44 151.7 1.2 8.6e-44 149.8 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase Glycos_transf_1 PF00534.15 ETS77280.1 - 3.6e-15 55.8 0.0 7.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS77280.1 - 2.1e-05 24.7 0.0 7.8e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 ETS77280.1 - 5.5e-05 22.8 0.0 0.00027 20.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_2 PF13524.1 ETS77280.1 - 0.053 13.7 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 HAUS4 PF14735.1 ETS77280.1 - 0.35 10.1 0.2 0.73 9.0 0.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Spherulin4 PF12138.3 ETS77281.1 - 4.5e-66 222.8 2.5 5.2e-66 222.6 1.7 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Polysacc_synt PF01943.12 ETS77281.1 - 0.0083 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4064 PF13273.1 ETS77281.1 - 0.032 14.3 0.4 0.08 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) TerC PF03741.11 ETS77281.1 - 0.062 12.7 0.2 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF3792 PF12670.2 ETS77281.1 - 0.067 13.0 0.4 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Spherulin4 PF12138.3 ETS77282.1 - 4.3e-52 177.0 0.0 4.9e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 TrmB PF01978.14 ETS77282.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Epimerase PF01370.16 ETS77283.1 - 1.4e-36 126.1 0.0 2.3e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 ETS77283.1 - 8e-16 57.7 0.1 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 ETS77283.1 - 1.4e-08 34.0 0.0 1.6e-07 30.5 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS77283.1 - 5.6e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETS77283.1 - 6.3e-06 25.2 0.0 1.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 ETS77283.1 - 7e-06 25.8 0.0 1.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS77283.1 - 8.2e-05 21.4 0.0 0.00039 19.2 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 ETS77283.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 ETS77283.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sua5_yciO_yrdC PF01300.13 ETS77284.1 - 0.034 13.4 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination NAD_binding_4 PF07993.7 ETS77286.1 - 2e-28 98.9 0.0 3.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS77286.1 - 9.1e-21 73.7 0.0 6e-20 71.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 ETS77286.1 - 2.8e-09 36.7 0.0 9.7e-09 34.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS77286.1 - 7.8e-07 29.2 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 ETS77286.1 - 1.2e-05 25.4 0.0 0.018 15.0 0.0 2.8 2 1 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 ETS77286.1 - 0.036 13.3 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 ETS77286.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS77286.1 - 0.11 11.1 0.0 10 4.7 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DLH PF01738.13 ETS77287.1 - 3.9e-20 72.0 0.0 1.3e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS77287.1 - 2.5e-07 30.5 0.0 4.1e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.18 ETS77288.1 - 9.5e-29 100.6 5.8 1.9e-28 99.6 4.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS77288.1 - 3.1e-05 23.9 2.0 3.2e-05 23.9 0.2 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_42 PF02449.10 ETS77289.1 - 5.3e-110 368.0 8.3 7.7e-110 367.5 5.7 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 ETS77289.1 - 1.7e-28 99.2 0.0 3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Cellulase PF00150.13 ETS77289.1 - 6.6e-05 22.2 2.5 0.00023 20.4 1.1 2.0 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.1 ETS77289.1 - 0.00019 21.2 0.6 0.0011 18.6 0.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_14 PF01373.12 ETS77289.1 - 0.0065 15.2 0.1 0.053 12.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 14 FAD_binding_3 PF01494.14 ETS77290.1 - 1.7e-14 53.6 0.1 0.00016 20.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 ETS77290.1 - 0.00032 20.6 0.1 0.00065 19.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS77290.1 - 0.00097 18.1 0.0 0.0069 15.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 ETS77290.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS77290.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETS77290.1 - 0.082 12.7 0.1 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77290.1 - 0.11 11.2 0.1 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain CLP_protease PF00574.18 ETS77292.1 - 1.4e-66 223.6 0.0 1.8e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.11 ETS77292.1 - 0.0075 15.0 0.1 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 Serine dehydrogenase proteinase DUF3546 PF12066.3 ETS77292.1 - 0.079 12.9 0.5 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) pKID PF02173.12 ETS77292.1 - 0.11 11.7 0.7 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 pKID domain ECH PF00378.15 ETS77292.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Cast PF10174.4 ETS77295.1 - 6.1e-05 21.2 1.3 8.8e-05 20.7 0.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Tropomyosin PF00261.15 ETS77295.1 - 0.01 14.9 0.9 0.02 14.0 0.6 1.3 1 0 0 1 1 1 0 Tropomyosin APG6 PF04111.7 ETS77295.1 - 0.02 13.9 0.7 0.032 13.2 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 ETS77295.1 - 0.032 12.9 0.4 0.066 11.8 0.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.6 ETS77295.1 - 0.049 13.6 0.8 0.14 12.1 0.6 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase CCDC144C PF14915.1 ETS77295.1 - 0.053 12.4 2.2 0.05 12.5 0.6 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region ATG16 PF08614.6 ETS77295.1 - 0.053 13.3 3.3 0.12 12.1 2.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3847 PF12958.2 ETS77295.1 - 0.071 12.8 1.4 0.26 11.0 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) GAS PF13851.1 ETS77295.1 - 0.074 12.2 2.4 0.14 11.2 1.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.8 ETS77295.1 - 0.11 11.4 4.6 0.22 10.4 3.2 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.4 ETS77295.1 - 0.16 11.8 3.9 0.092 12.6 0.5 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LXG PF04740.7 ETS77295.1 - 0.26 11.0 1.8 1.6 8.4 0.5 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily GrpE PF01025.14 ETS77295.1 - 0.27 10.7 3.7 0.28 10.6 1.7 1.7 1 1 0 1 1 1 0 GrpE COG2 PF06148.6 ETS77295.1 - 0.52 10.1 4.1 1.1 9.1 0.3 2.7 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 ETS77295.1 - 0.67 9.5 4.8 0.29 10.6 1.2 1.9 2 1 0 2 2 2 0 IncA protein DUF972 PF06156.8 ETS77295.1 - 3.1 8.1 5.5 34 4.8 3.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Clr5 PF14420.1 ETS77297.1 - 4.9e-19 67.9 0.9 4.9e-19 67.9 0.6 2.8 2 1 0 2 2 2 1 Clr5 domain SpoVIF PF14069.1 ETS77297.1 - 0.019 14.7 0.1 0.057 13.1 0.1 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F DUF2361 PF10153.4 ETS77297.1 - 0.35 11.0 3.1 0.19 11.9 0.4 1.9 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2361) DUF1673 PF07895.6 ETS77298.1 - 0.064 12.7 4.9 0.78 9.2 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1700 PF08006.6 ETS77298.1 - 4.6 6.4 8.7 7 5.9 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DAO PF01266.19 ETS77299.1 - 1.2e-53 182.3 1.3 1.4e-53 182.0 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77299.1 - 4.3e-05 23.4 0.7 0.00012 22.0 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS77299.1 - 0.0002 21.5 0.2 0.046 13.7 0.2 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77299.1 - 0.0033 17.3 0.0 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77299.1 - 0.0074 15.1 2.1 0.024 13.5 1.4 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS77299.1 - 0.036 13.8 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS77299.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_76 PF03663.9 ETS77300.1 - 1.5e-109 366.7 8.5 1.8e-109 366.5 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 F-box-like PF12937.2 ETS77301.1 - 0.00017 21.2 0.2 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS77301.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain BAR PF03114.13 ETS77303.1 - 6.5e-64 215.5 3.1 7.8e-64 215.3 2.2 1.1 1 0 0 1 1 1 1 BAR domain Pept_tRNA_hydro PF01195.14 ETS77304.1 - 4.2e-26 91.5 0.0 5.2e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase TauD PF02668.11 ETS77305.1 - 9.5e-39 133.6 0.9 1.2e-38 133.2 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 ETS77305.1 - 0.022 15.2 0.2 7.8 7.0 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3830 PF12903.2 ETS77306.1 - 2.4e-26 91.8 0.0 3.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Fungal_trans PF04082.13 ETS77307.1 - 0.00011 21.1 0.1 0.00043 19.2 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77307.1 - 0.00041 20.1 8.1 0.00071 19.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 ETS77308.1 - 6.6e-115 384.1 46.4 8e-115 383.8 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS77308.1 - 1.5e-31 109.4 50.3 1.7e-31 109.2 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease DHDPS PF00701.17 ETS77309.1 - 4.4e-31 107.5 0.0 6.8e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HpcH_HpaI PF03328.9 ETS77310.1 - 4.7e-53 179.3 0.0 5.8e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Response_reg PF00072.19 ETS77310.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain UAA PF08449.6 ETS77311.1 - 6.1e-12 45.0 19.3 7.8e-12 44.7 13.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 ETS77311.1 - 1.6e-07 31.0 5.8 1.6e-07 31.0 4.0 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS77311.1 - 0.011 15.7 29.4 0.019 15.0 5.4 2.3 2 0 0 2 2 2 0 EamA-like transporter family Peptidase_A24 PF01478.13 ETS77311.1 - 0.027 14.6 0.1 0.027 14.6 0.1 3.9 2 2 1 3 3 3 0 Type IV leader peptidase family DUF1077 PF06417.7 ETS77311.1 - 1.7 8.0 5.6 9.6 5.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) Pkinase PF00069.20 ETS77312.1 - 3.4e-49 167.3 0.0 4.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77312.1 - 1.8e-29 102.6 0.0 2.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS77312.1 - 0.053 12.4 0.1 8.1 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pyr_redox_3 PF13738.1 ETS77313.1 - 1.4e-25 90.5 0.0 7.2e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS77313.1 - 4.7e-10 38.9 0.0 1.5e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 ETS77313.1 - 8.1e-10 37.5 0.0 7.5e-09 34.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS77313.1 - 3e-07 30.3 0.0 6.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS77313.1 - 0.00017 21.3 0.3 0.014 15.2 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amidoligase_2 PF12224.3 ETS77314.1 - 7.4e-12 45.4 1.0 1.6e-10 41.0 0.7 2.7 1 1 0 1 1 1 1 Putative amidoligase enzyme DUF346 PF03984.8 ETS77314.1 - 0.088 12.2 0.2 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) MBOAT PF03062.14 ETS77316.1 - 1.3e-34 119.8 15.6 2.2e-34 119.0 10.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DnaJ PF00226.26 ETS77317.1 - 1.6e-20 72.5 1.8 4.7e-20 71.0 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain ADH_N PF08240.7 ETS77319.1 - 9.6e-22 76.8 1.4 1.5e-21 76.1 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS77319.1 - 1.1e-20 73.5 0.0 1.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS77319.1 - 2.2e-06 28.6 0.0 3.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS77319.1 - 0.001 18.2 0.1 0.0018 17.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 ETS77320.1 - 3.2e-16 59.7 6.7 5.4e-15 55.7 4.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS77320.1 - 5.2e-08 32.7 4.0 8.2e-06 25.6 0.7 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 ETS77320.1 - 6.4e-05 22.8 2.5 0.00012 21.9 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS77320.1 - 8.3e-05 22.6 1.5 0.00025 21.1 1.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 ETS77320.1 - 0.00021 21.4 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 ETS77320.1 - 0.0017 17.8 0.0 0.068 12.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS77320.1 - 0.0018 18.0 0.1 0.0059 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 ETS77320.1 - 0.012 15.2 0.1 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 ETS77320.1 - 0.055 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_2 PF13380.1 ETS77320.1 - 0.073 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain Wax2_C PF12076.3 ETS77320.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Kdo PF06293.9 ETS77321.1 - 2.6e-07 29.8 0.0 3.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 ETS77321.1 - 2e-06 27.1 0.0 2.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 ETS77321.1 - 3.8e-05 23.5 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS77321.1 - 0.00043 19.9 0.0 0.099 12.2 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase EcKinase PF02958.15 ETS77321.1 - 0.013 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase HSP90 PF00183.13 ETS77322.1 - 1.5e-257 855.2 32.9 1.8e-257 855.0 22.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 ETS77322.1 - 3.3e-12 46.2 0.4 3.3e-12 46.2 0.3 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETS77322.1 - 2.7e-11 43.1 0.1 4.9e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 ETS77322.1 - 0.07 13.4 0.4 0.07 13.4 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 ETS77322.1 - 0.072 12.8 2.1 0.076 12.7 0.2 2.0 2 0 0 2 2 2 0 Tumour suppressor protein Peptidase_S10 PF00450.17 ETS77322.1 - 0.31 10.1 4.4 0.44 9.6 0.0 2.3 1 1 1 2 2 2 0 Serine carboxypeptidase AA_permease_2 PF13520.1 ETS77323.1 - 9.1e-19 67.2 10.5 1e-18 67.1 7.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS77323.1 - 3.3e-09 35.6 14.6 6.3e-09 34.6 10.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS77324.1 - 1.3e-07 30.5 4.5 1.5e-07 30.3 3.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS77324.1 - 1.4e-05 23.6 2.4 1.5e-05 23.5 1.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4611 PF15387.1 ETS77325.1 - 0.079 13.1 0.3 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Auxin_repressed PF05564.7 ETS77325.1 - 0.23 12.0 2.8 2.8 8.5 1.7 2.1 2 0 0 2 2 2 0 Dormancy/auxin associated protein PBP1_TM PF14812.1 ETS77325.1 - 2.5 8.4 4.8 3.7 7.9 3.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COX4_pro_2 PF07835.7 ETS77326.1 - 0.078 12.9 1.9 0.34 10.9 1.3 2.2 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV E1-E2_ATPase PF00122.15 ETS77326.1 - 0.095 11.7 2.1 0.19 10.7 1.4 1.6 1 0 0 1 1 1 0 E1-E2 ATPase FMN_dh PF01070.13 ETS77327.1 - 8.7e-85 284.6 0.0 9.4e-82 274.6 0.0 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_M19 PF01244.16 ETS77327.1 - 0.00029 19.8 0.0 0.00078 18.4 0.0 1.6 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) IMPDH PF00478.20 ETS77327.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TPR_12 PF13424.1 ETS77328.1 - 0.0019 18.0 0.1 0.016 15.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc5 PF12862.2 ETS77328.1 - 0.12 12.2 1.2 0.72 9.7 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Methyltransf_23 PF13489.1 ETS77329.1 - 0.0042 16.8 0.0 0.0088 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETS77329.1 - 0.0046 16.2 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 ETS77329.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77329.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77329.1 - 0.023 15.2 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77329.1 - 0.047 14.1 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ferritin_2 PF13668.1 ETS77331.1 - 1.5e-47 161.0 2.3 1.9e-47 160.6 1.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain NOB1_Zn_bind PF08772.6 ETS77332.1 - 1.1e-32 111.6 2.9 2e-32 110.8 2.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 ETS77332.1 - 0.006 16.4 16.0 0.048 13.5 11.1 2.5 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 ETS77332.1 - 0.02 14.4 0.7 0.02 14.4 0.5 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RRP7 PF12923.2 ETS77332.1 - 0.098 12.6 0.3 0.098 12.6 0.2 2.3 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Nop10p PF04135.7 ETS77333.1 - 1.1e-18 66.7 0.0 1.3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Oxidored_FMN PF00724.15 ETS77334.1 - 5.3e-96 321.5 0.0 6.1e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 ETS77334.1 - 0.017 14.4 0.0 1.9 7.7 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel GMC_oxred_N PF00732.14 ETS77335.1 - 1.1e-44 152.8 0.6 1.6e-42 145.6 0.1 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS77335.1 - 1.5e-26 93.4 0.4 4.5e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 ETS77335.1 - 4.4e-08 32.4 3.6 0.00061 18.8 0.5 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77335.1 - 3.6e-06 26.8 0.1 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77335.1 - 4.6e-06 25.7 0.2 1e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS77335.1 - 8.8e-05 22.4 0.3 0.00036 20.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS77335.1 - 0.00013 21.1 0.7 0.0003 19.9 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS77335.1 - 0.00044 19.4 0.1 0.0011 18.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETS77335.1 - 0.0025 16.3 0.5 0.0052 15.3 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein Gluconate_2-dh3 PF13618.1 ETS77335.1 - 0.027 14.6 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 FAD_oxidored PF12831.2 ETS77335.1 - 0.03 13.4 1.9 0.098 11.7 0.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS77335.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 ETS77335.1 - 0.14 12.6 1.5 0.34 11.3 0.8 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS77335.1 - 0.17 11.5 0.5 0.32 10.6 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 ETS77336.1 - 7.4e-24 84.9 0.0 1.3e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS77336.1 - 1.3e-16 59.9 0.0 5.1e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS77336.1 - 2.8e-12 46.4 0.0 1.9e-10 40.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS77336.1 - 9.2e-09 34.7 0.0 2.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 ETS77336.1 - 2.4e-07 29.9 0.4 0.00019 20.4 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS77336.1 - 3e-07 29.7 0.6 0.00021 20.3 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.1 ETS77336.1 - 3.8e-06 26.0 0.0 0.001 18.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS77336.1 - 2.9e-05 24.0 0.0 0.17 11.7 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS77336.1 - 0.0015 18.8 0.0 0.71 10.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS77336.1 - 0.0037 17.0 0.1 0.35 10.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS77336.1 - 0.015 14.1 0.0 0.062 12.1 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 ETS77336.1 - 0.033 14.4 0.0 0.089 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.10 ETS77336.1 - 0.049 11.8 0.0 4.6 5.3 0.0 2.7 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.15 ETS77336.1 - 0.078 13.0 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 ETS77336.1 - 0.21 10.0 0.0 0.89 7.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.8 ETS77337.1 - 6.5e-25 87.9 0.0 8.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS77337.1 - 6.7e-18 64.4 0.0 2.1e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS77337.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS77337.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 ETS77337.1 - 0.05 12.3 1.0 0.17 10.5 0.7 1.7 1 1 0 1 1 1 0 Carboxylesterase family DUF3089 PF11288.3 ETS77337.1 - 0.062 12.4 0.0 0.17 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 ETS77337.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain AMP-binding PF00501.23 ETS77338.1 - 2.9e-89 299.3 0.1 3.6e-89 299.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS77338.1 - 8.9e-22 77.8 0.1 3.5e-19 69.5 0.2 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Rep_fac_C PF08542.6 ETS77339.1 - 1.9e-23 82.2 0.1 4.8e-23 80.9 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETS77339.1 - 2e-11 43.8 0.0 3.9e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 ETS77339.1 - 1.4e-06 28.4 0.1 3.5e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS77339.1 - 6.1e-06 26.4 0.8 0.00013 22.1 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS77339.1 - 0.00022 21.2 1.5 0.043 13.7 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 ETS77339.1 - 0.0069 16.4 0.3 0.27 11.2 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 ETS77339.1 - 0.0076 16.1 0.1 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS77339.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF2861 PF11060.3 ETS77339.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) Arch_ATPase PF01637.13 ETS77339.1 - 0.023 14.3 0.1 0.062 12.9 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase T4SS-DNA_transf PF02534.9 ETS77339.1 - 0.032 12.8 0.1 0.14 10.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 ETS77339.1 - 0.042 12.5 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 ETS77339.1 - 0.047 13.1 0.1 2 7.7 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain SNF2_N PF00176.18 ETS77339.1 - 0.057 12.1 0.1 0.083 11.6 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Aconitase_B_N PF11791.3 ETS77339.1 - 0.066 13.0 0.0 5.9 6.6 0.0 3.0 3 0 0 3 3 3 0 Aconitate B N-terminal domain AAA_29 PF13555.1 ETS77339.1 - 0.11 11.9 0.1 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.16 ETS77340.1 - 1e-34 120.1 0.0 1.1e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 ETS77341.1 - 2.1e-14 52.7 11.1 0.0001 22.0 0.0 7.6 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 ETS77341.1 - 0.00011 22.0 0.4 0.015 14.9 0.1 3.9 4 1 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 ETS77341.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 LisH Yeast-kill-tox PF09207.6 ETS77341.1 - 0.0032 17.8 0.3 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 Yeast killer toxin IKI3 PF04762.7 ETS77341.1 - 0.22 9.3 0.0 0.49 8.1 0.0 1.6 2 0 0 2 2 2 0 IKI3 family DUF1751 PF08551.5 ETS77342.1 - 2.1e-25 88.8 4.6 2.1e-25 88.8 3.2 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 ETS77342.1 - 1.4 8.9 11.9 2.6 8.0 8.2 1.4 1 0 0 1 1 1 0 Rhomboid family TPR_1 PF00515.23 ETS77343.1 - 3.7e-50 165.5 29.6 4.4e-08 32.4 0.0 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETS77343.1 - 8.1e-50 166.3 38.6 1.5e-13 50.2 1.6 6.5 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 ETS77343.1 - 4e-45 148.1 22.2 4.2e-06 26.2 0.0 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETS77343.1 - 6.8e-40 131.8 16.5 8e-06 25.2 0.6 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 ETS77343.1 - 2.1e-33 114.2 9.3 4.7e-08 33.4 0.0 6.7 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 ETS77343.1 - 8.6e-30 100.4 16.9 0.0013 18.7 0.1 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 ETS77343.1 - 4.9e-28 96.8 21.8 1.9e-06 27.6 1.2 7.2 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 ETS77343.1 - 4.2e-27 92.1 11.1 0.00048 20.5 0.0 9.7 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_19 PF14559.1 ETS77343.1 - 3.8e-23 81.5 15.4 0.00018 21.8 0.1 6.5 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETS77343.1 - 7e-21 72.3 10.5 0.0016 18.1 0.0 9.5 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 ETS77343.1 - 3.6e-20 70.9 16.3 0.0024 18.2 0.0 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 ETS77343.1 - 3.1e-16 59.2 7.7 1.7e-08 34.4 1.1 4.1 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 ETS77343.1 - 9.7e-12 44.5 12.5 0.00084 19.1 0.2 6.8 1 1 7 9 9 9 5 Tetratricopeptide repeat TPR_15 PF13429.1 ETS77343.1 - 5e-11 42.1 7.3 0.00025 20.2 0.1 4.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 ETS77343.1 - 2.1e-05 24.5 2.0 0.49 10.5 0.0 4.1 3 2 2 5 5 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 ETS77343.1 - 0.011 15.1 1.7 0.71 9.2 0.0 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 ETS77343.1 - 0.075 12.9 19.3 1.1 9.2 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.13 ETS77343.1 - 0.23 11.3 14.3 1.7 8.5 0.8 5.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 ETS77343.1 - 0.25 11.2 20.6 0.37 10.7 0.0 4.9 6 1 1 7 7 6 0 Tetratricopeptide repeat SNAP PF14938.1 ETS77343.1 - 1.1 8.3 13.1 13 4.8 0.2 4.5 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP Ribosomal_L3 PF00297.17 ETS77344.1 - 7.5e-117 389.3 7.2 9.5e-117 389.0 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.6 ETS77345.1 - 0.0037 17.1 0.3 0.22 11.4 0.2 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein DUF2341 PF10102.4 ETS77345.1 - 0.059 13.5 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) Chorismate_bind PF00425.13 ETS77346.1 - 3.9e-88 295.0 0.0 9.3e-88 293.8 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 ETS77346.1 - 1.3e-27 96.4 0.0 1.9e-23 83.0 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region GFA PF04828.9 ETS77347.1 - 9.1e-07 28.7 0.1 9.1e-07 28.7 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 ETS77347.1 - 0.007 15.5 0.2 0.007 15.5 0.1 2.6 3 0 0 3 3 3 1 zinc-ribbon domain A2L_zn_ribbon PF08792.5 ETS77347.1 - 0.012 14.9 0.1 0.012 14.9 0.1 2.5 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 ETS77347.1 - 0.051 13.0 0.1 0.051 13.0 0.1 2.7 3 1 0 2 2 2 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 ETS77347.1 - 0.44 10.4 7.3 0.54 10.2 1.4 2.6 2 1 1 3 3 3 0 Cysteine-rich CWC Sec6 PF06046.8 ETS77348.1 - 9e-157 522.5 5.2 1.1e-156 522.2 3.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 ETS77348.1 - 0.031 13.0 5.3 0.03 13.0 0.6 2.8 3 1 0 3 3 3 0 Vps53-like, N-terminal MutS_III PF05192.13 ETS77348.1 - 0.1 12.3 0.1 1.2 8.9 0.1 2.9 1 1 0 1 1 1 0 MutS domain III DUF2450 PF10475.4 ETS77348.1 - 1.9 7.3 7.4 1.2 7.9 0.3 3.2 3 1 1 4 4 4 0 Protein of unknown function N-terminal domain (DUF2450) MFS_1 PF07690.11 ETS77349.1 - 1.3e-08 33.9 29.1 1.3e-08 33.9 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS77349.1 - 2.1e-06 27.3 2.8 2.1e-06 27.3 2.0 2.9 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 HET PF06985.6 ETS77352.1 - 1.8e-21 76.7 6.6 1.5e-19 70.5 4.6 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3417 PF11897.3 ETS77352.1 - 0.069 13.1 0.8 0.85 9.5 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) Glyco_hydro_18 PF00704.23 ETS77353.1 - 5.8e-74 249.5 8.4 5.8e-74 249.5 5.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS77353.1 - 2e-09 37.2 17.9 2e-09 37.2 12.4 4.3 4 1 0 4 4 4 2 Chitin recognition protein DNase_NucA_NucB PF14040.1 ETS77353.1 - 0.0023 18.0 0.6 0.032 14.3 0.3 2.4 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 ETS77354.1 - 9.3e-10 38.2 0.2 0.0011 18.8 0.0 3.2 3 0 0 3 3 3 2 LysM domain WD40 PF00400.27 ETS77356.1 - 2.2e-21 74.8 1.5 1.5e-12 46.8 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 ETS77356.1 - 7e-06 24.4 1.5 0.013 13.7 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HET PF06985.6 ETS77357.1 - 2.1e-26 92.7 0.6 3.1e-26 92.1 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 ETS77358.1 - 1.3e-13 50.2 0.0 8.5e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 ETS77358.1 - 4e-10 39.0 0.3 1.9e-09 36.8 0.2 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 ETS77358.1 - 8.5e-08 32.0 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS77358.1 - 5.2e-07 29.8 0.1 5.6e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 ETS77358.1 - 5e-05 23.5 1.1 0.00053 20.2 0.1 2.9 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS77358.1 - 0.00034 20.7 0.0 0.00098 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS77358.1 - 0.0023 17.6 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS77358.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.3 ETS77358.1 - 0.0041 15.3 0.0 0.0065 14.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RNA_helicase PF00910.17 ETS77358.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 ETS77358.1 - 0.03 13.2 0.0 0.072 11.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 ETS77358.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 ETS77358.1 - 0.055 13.1 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETS77358.1 - 0.067 14.0 0.0 0.37 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS77358.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Parvo_NS1 PF01057.12 ETS77358.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 ETS77358.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Herpes_UL31 PF02718.9 ETS77358.1 - 0.12 11.0 0.0 1.6 7.3 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus UL31-like protein AAA_5 PF07728.9 ETS77358.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 ETS77358.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETS77358.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 ETS77358.1 - 0.15 11.3 0.1 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein KAP_NTPase PF07693.9 ETS77358.1 - 0.17 10.8 0.1 0.46 9.4 0.0 1.6 1 1 1 2 2 2 0 KAP family P-loop domain HET PF06985.6 ETS77359.1 - 1.2e-22 80.5 0.0 2.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS77360.1 - 3.8e-41 141.0 0.0 4.8e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 ETS77361.1 - 8.9e-10 38.8 0.1 1.9e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77361.1 - 3.3e-09 36.6 0.1 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CcdB PF01845.12 ETS77361.1 - 0.039 13.8 0.0 0.096 12.6 0.0 1.6 2 0 0 2 2 2 0 CcdB protein ABC_tran PF00005.22 ETS77362.1 - 2.6e-42 144.3 0.0 9.4e-27 93.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS77362.1 - 8.1e-32 110.7 33.0 1.8e-24 86.6 9.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS77362.1 - 3.6e-12 45.9 0.1 7.6e-05 22.0 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS77362.1 - 4.1e-10 40.0 0.1 0.028 14.3 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETS77362.1 - 4.2e-08 33.7 0.1 0.00064 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS77362.1 - 1.4e-07 30.9 0.8 0.0088 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS77362.1 - 6.5e-07 29.5 0.1 0.00017 21.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS77362.1 - 1e-06 28.4 0.3 0.019 14.4 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 ETS77362.1 - 2.7e-06 27.3 0.2 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS77362.1 - 2e-05 24.0 0.9 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS77362.1 - 2.3e-05 25.1 0.2 0.0063 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS77362.1 - 4.3e-05 23.5 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS77362.1 - 9.3e-05 21.9 0.1 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 ETS77362.1 - 9.3e-05 22.1 0.3 0.023 14.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 ETS77362.1 - 0.00025 20.0 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF258 PF03193.11 ETS77362.1 - 0.00079 18.6 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETS77362.1 - 0.00095 19.4 0.4 0.032 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS77362.1 - 0.0017 18.3 0.1 2.7 7.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 ETS77362.1 - 0.0028 17.5 0.0 2.2 8.2 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 ETS77362.1 - 0.0032 17.9 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 ETS77362.1 - 0.0045 16.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS77362.1 - 0.0051 16.6 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 ETS77362.1 - 0.0092 15.4 3.2 0.12 11.8 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 ETS77362.1 - 0.012 15.2 0.5 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 ETS77362.1 - 0.02 13.7 0.9 0.16 10.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETS77362.1 - 0.034 13.2 0.3 0.32 10.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 ETS77362.1 - 0.051 12.8 2.0 0.3 10.3 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein GTP_EFTU PF00009.22 ETS77362.1 - 0.058 12.8 0.2 6.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 ETS77362.1 - 0.063 12.4 0.1 0.61 9.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 ETS77362.1 - 0.067 12.8 2.0 0.25 10.9 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 ETS77362.1 - 0.098 12.6 0.2 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 ETS77362.1 - 0.11 12.0 0.8 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 ETS77362.1 - 0.16 11.6 0.8 0.62 9.7 0.0 2.3 3 0 0 3 3 2 0 NTPase Arch_ATPase PF01637.13 ETS77362.1 - 0.18 11.4 0.2 5.5 6.6 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase AAA_19 PF13245.1 ETS77362.1 - 0.26 11.0 2.3 3.7 7.3 0.1 3.1 2 0 0 2 2 2 0 Part of AAA domain ATP-synt_ab PF00006.20 ETS77362.1 - 0.61 9.5 3.0 1.6 8.1 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 ETS77362.1 - 1.1 7.8 5.9 0.6 8.6 0.2 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF3584 PF12128.3 ETS77362.1 - 1.2 6.4 0.0 1.6 5.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 ETS77362.1 - 1.9 6.8 0.4 3.7 5.8 0.1 1.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 ETS77363.1 - 2.3e-22 79.2 38.2 5.1e-18 64.9 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 ETS77363.1 - 2e-06 26.2 7.0 2e-06 26.2 4.8 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector HET PF06985.6 ETS77364.1 - 9e-24 84.2 2.3 3.1e-19 69.5 0.1 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 ETS77365.1 - 9.8e-07 28.4 7.1 0.00033 20.2 0.5 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein 7TM_GPCR_Sru PF10322.4 ETS77365.1 - 0.0045 16.1 0.1 0.0085 15.2 0.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru DUF4199 PF13858.1 ETS77365.1 - 0.015 15.2 0.4 0.04 13.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) VanZ PF04892.7 ETS77365.1 - 0.086 12.7 1.1 0.67 9.9 0.8 2.1 1 1 0 1 1 1 0 VanZ like family ALS_ss_C PF10369.4 ETS77367.1 - 1.1e-17 63.5 0.0 1.3e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 ETS77367.1 - 4.5e-13 48.3 0.1 8.1e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 ETS77367.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain OTCace_N PF02729.16 ETS77368.1 - 1.7e-42 144.4 0.1 2.5e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 ETS77368.1 - 5.5e-41 140.0 0.0 1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain KH_1 PF00013.24 ETS77369.1 - 2.1e-11 43.2 0.0 5.7e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 ETS77369.1 - 2.1e-07 30.4 2.0 3e-05 23.5 0.0 3.2 3 0 0 3 3 3 2 KH domain CDK2AP PF09806.4 ETS77369.1 - 9.3 6.4 13.5 5.2 7.2 0.1 2.8 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DEAD PF00270.24 ETS77370.1 - 3.5e-30 104.7 0.6 2.8e-14 52.9 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS77370.1 - 6.9e-20 70.6 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS77370.1 - 8.1e-06 25.7 0.6 3.3e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 ETS77370.1 - 0.017 14.4 1.8 0.13 11.4 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PIGA PF08288.7 ETS77371.1 - 4.2e-46 155.2 3.8 6.9e-46 154.5 0.5 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 ETS77371.1 - 3.1e-28 98.3 0.0 5.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 ETS77371.1 - 9.5e-17 61.2 0.3 1.7e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 ETS77371.1 - 1.3e-14 54.4 0.0 2.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETS77371.1 - 9e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 ETS77371.1 - 3.7e-07 30.0 0.2 6.1e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 ETS77371.1 - 0.0032 17.7 0.0 0.0091 16.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF605 PF04652.11 ETS77372.1 - 5.4 6.3 16.4 6 6.1 11.3 1.2 1 0 0 1 1 1 0 Vta1 like DUF2987 PF11205.3 ETS77373.1 - 0.86 9.2 11.9 21 4.7 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2987) Spore_GerAC PF05504.6 ETS77373.1 - 3.9 7.2 15.5 15 5.3 0.0 4.7 4 1 1 5 5 5 0 Spore germination B3/ GerAC like, C-terminal AT_hook PF02178.14 ETS77373.1 - 6.9 6.7 13.5 0.52 10.1 4.3 2.6 2 0 0 2 2 2 0 AT hook motif RCR PF12273.3 ETS77374.1 - 0.11 13.0 1.7 0.21 12.1 1.2 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ribonuclease_3 PF00636.21 ETS77375.1 - 2.5e-37 127.7 0.0 6.7e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETS77375.1 - 2.7e-22 79.0 0.0 7.4e-10 38.8 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 ETS77375.1 - 7.1e-20 71.1 0.1 1.6e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS77375.1 - 3.9e-16 58.6 0.0 1.4e-15 56.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 ETS77375.1 - 7.8e-16 57.6 1.1 4e-15 55.3 0.2 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 ETS77375.1 - 6.1e-13 49.0 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 ETS77375.1 - 1.6e-07 31.7 0.2 0.0027 18.2 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Apocytochr_F_C PF01333.14 ETS77375.1 - 0.0037 17.0 0.3 0.0081 15.9 0.2 1.5 1 0 0 1 1 1 1 Apocytochrome F, C-terminal RCC1 PF00415.13 ETS77376.1 - 4e-17 62.1 1.7 3.3e-07 30.4 0.0 5.0 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS77376.1 - 6.8e-17 60.6 5.7 1.6e-05 24.3 0.4 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Proteasome PF00227.21 ETS77377.1 - 5.6e-57 192.1 0.0 2e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 ETS77377.1 - 2e-11 43.0 0.3 4.2e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 ETS77378.1 - 1.4e-08 34.6 7.7 1.4e-08 34.6 5.3 1.8 2 0 0 2 2 2 1 RING-variant domain PHD PF00628.24 ETS77378.1 - 0.16 11.6 8.8 0.043 13.5 3.7 1.8 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.7 ETS77379.1 - 5.9e-72 242.0 0.0 7.1e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 ETS77379.1 - 0.00085 18.6 0.0 0.077 12.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.14 ETS77380.1 - 6.1e-19 67.7 0.0 8.8e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETS77380.1 - 0.0003 19.6 0.0 0.00045 19.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V BCDHK_Adom3 PF10436.4 ETS77381.1 - 7.6e-70 233.6 0.0 1.1e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETS77381.1 - 2.3e-17 62.7 0.0 6e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS77381.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Packaging_FI PF14000.1 ETS77382.1 - 0.039 14.1 0.2 0.039 14.1 0.2 3.0 3 0 0 3 3 3 0 DNA packaging protein FI DUF342 PF03961.8 ETS77382.1 - 0.37 9.1 4.4 0.56 8.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 ETS77382.1 - 0.4 9.0 12.4 0.51 8.7 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MerR-DNA-bind PF09278.6 ETS77382.1 - 2.4 8.6 11.4 7.3 7.0 5.6 2.8 2 0 0 2 2 2 0 MerR, DNA binding Sugar_tr PF00083.19 ETS77383.1 - 1.6e-85 287.3 25.3 2e-85 287.0 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77383.1 - 4.1e-23 81.6 53.8 3.4e-22 78.6 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Stc1 PF12898.2 ETS77385.1 - 3.2e-18 65.5 0.2 5.9e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Stc1 domain Nop14 PF04147.7 ETS77385.1 - 1.4 6.7 8.5 1.9 6.3 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETS77385.1 - 9.7 5.3 8.2 15 4.7 5.7 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.20 ETS77386.1 - 5.8e-58 196.0 0.0 8.2e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77386.1 - 2.3e-30 105.5 0.0 7.5e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS77386.1 - 0.023 13.5 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSP70 PF00012.15 ETS77387.1 - 5.9e-09 34.3 0.1 4.5e-08 31.4 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein SNF2_N PF00176.18 ETS77388.1 - 1.3e-61 208.0 0.0 1.8e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETS77388.1 - 6.3e-10 38.8 0.0 5.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS77388.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 ETS77388.1 - 6.8e-06 26.0 3.7 1.7e-05 24.7 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 ETS77388.1 - 8.7e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 ETS77388.1 - 6.9e-05 22.4 7.3 0.00016 21.3 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS77388.1 - 0.00075 19.1 4.4 0.0018 17.9 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS77388.1 - 0.00081 19.0 7.8 0.002 17.7 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS77388.1 - 0.0063 16.3 6.6 0.015 15.1 4.6 1.7 1 0 0 1 1 1 1 Ring finger domain AAA_34 PF13872.1 ETS77388.1 - 0.0097 14.7 0.1 0.02 13.6 0.0 1.6 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 NACHT PF05729.7 ETS77389.1 - 4.8e-11 42.5 0.1 3.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain zf-C2H2_4 PF13894.1 ETS77389.1 - 4.2e-08 32.9 23.6 0.015 15.5 0.2 6.4 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS77389.1 - 4.1e-07 29.9 27.9 0.0011 19.2 0.3 5.9 6 0 0 6 6 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS77389.1 - 4.5e-05 23.5 21.0 0.067 13.5 0.0 6.7 6 0 0 6 6 6 2 Zinc-finger double domain AAA_16 PF13191.1 ETS77389.1 - 0.00018 21.5 1.9 0.001 19.0 0.0 3.3 4 1 0 4 4 4 1 AAA ATPase domain zf-C2H2_jaz PF12171.3 ETS77389.1 - 0.00053 20.0 13.7 0.069 13.3 0.0 4.6 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 ETS77389.1 - 0.0009 19.3 1.2 0.0028 17.7 0.8 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding AAA_22 PF13401.1 ETS77389.1 - 0.0042 17.2 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-met PF12874.2 ETS77389.1 - 0.006 16.7 5.4 0.7 10.1 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AAA PF00004.24 ETS77389.1 - 0.019 15.1 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-XS PF03470.9 ETS77389.1 - 0.019 15.0 0.8 0.051 13.6 0.5 1.8 1 0 0 1 1 1 0 XS zinc finger domain Rapamycin_bind PF08771.6 ETS77389.1 - 0.067 13.2 1.1 2.2 8.3 0.1 2.8 2 0 0 2 2 2 0 Rapamycin binding domain Gag_p12 PF01141.13 ETS77390.1 - 0.034 14.2 0.3 0.32 11.1 0.9 1.9 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Trp_halogenase PF04820.9 ETS77390.1 - 0.048 12.2 0.4 0.078 11.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Arteri_env PF01606.11 ETS77390.1 - 0.074 12.7 1.2 0.086 12.4 0.3 1.5 1 1 0 1 1 1 0 Arterivirus envelope protein HET PF06985.6 ETS77391.1 - 1.8e-23 83.2 1.2 3.3e-23 82.3 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1772 PF08592.6 ETS77392.1 - 1.7e-09 37.5 2.2 0.00015 21.4 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1772) Protocadherin PF08374.6 ETS77393.1 - 0.00067 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protocadherin DUF4448 PF14610.1 ETS77393.1 - 0.00095 18.7 1.5 0.0031 17.0 0.0 2.5 3 1 1 4 4 4 1 Protein of unknown function (DUF4448) RCR PF12273.3 ETS77393.1 - 0.0049 17.4 0.5 0.018 15.5 0.3 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 ETS77393.1 - 0.011 15.0 0.1 0.046 13.0 0.1 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 ETS77393.1 - 0.025 14.2 9.1 0.13 12.0 6.3 2.1 1 1 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.1 ETS77393.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain FAM163 PF15069.1 ETS77393.1 - 0.44 11.1 4.6 0.5 10.9 0.0 2.7 1 1 1 2 2 2 0 FAM163 family Podoplanin PF05808.6 ETS77393.1 - 2.8 7.4 9.7 0.34 10.4 2.2 2.3 2 1 1 3 3 3 0 Podoplanin FAD_binding_4 PF01565.18 ETS77396.1 - 3e-18 65.6 2.5 6.5e-18 64.5 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS77396.1 - 1.6e-11 43.8 0.1 3.4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS77396.1 - 0.00013 21.2 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.6 ETS77398.1 - 6.3e-36 123.6 0.5 9.9e-36 122.9 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BNR_2 PF13088.1 ETS77399.1 - 1.5e-08 34.2 0.1 9.8e-06 25.0 0.0 3.6 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 ETS77399.1 - 2.7e-08 32.4 19.5 0.44 10.5 0.8 6.7 6 0 0 6 6 6 4 BNR/Asp-box repeat LVIVD PF08309.6 ETS77399.1 - 0.045 12.7 0.1 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat RTA1 PF04479.8 ETS77400.1 - 1.6e-41 142.3 10.0 1.6e-41 142.3 7.0 1.3 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 ETS77401.1 - 0.00046 18.8 2.8 0.0018 16.9 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain CFEM PF05730.6 ETS77403.1 - 4.4e-11 42.4 10.6 7.5e-11 41.7 7.3 1.4 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.13 ETS77404.1 - 1e-29 103.2 0.1 1.7e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77404.1 - 8.3e-07 28.8 9.4 1.7e-06 27.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1275 PF06912.6 ETS77404.1 - 0.16 11.1 0.4 2.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) PLAC9 PF15205.1 ETS77404.1 - 0.17 12.1 0.2 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 Placenta-specific protein 9 MFS_1 PF07690.11 ETS77405.1 - 3.2e-34 118.1 24.2 4.7e-34 117.6 16.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sensor PF13796.1 ETS77405.1 - 0.00066 19.3 1.7 0.0022 17.6 1.2 2.0 1 1 0 1 1 1 1 Putative sensor DUF1228 PF06779.9 ETS77405.1 - 0.0013 18.7 1.1 0.074 13.0 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) HAD_2 PF13419.1 ETS77406.1 - 5.8e-39 134.1 0.0 6.8e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS77406.1 - 0.013 15.9 0.0 2.1 8.7 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_tranf_2_3 PF13641.1 ETS77406.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 STAT2_C PF12188.3 ETS77406.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Hydrolase_6 PF13344.1 ETS77406.1 - 0.073 12.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DAO PF01266.19 ETS77407.1 - 5.8e-48 163.6 0.2 6.7e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS77407.1 - 5.3e-05 23.3 0.1 0.003 17.6 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77407.1 - 0.00028 20.8 0.1 0.0007 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS77407.1 - 0.00042 20.1 1.6 0.01 15.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS77407.1 - 0.00043 19.2 0.2 0.33 9.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 ETS77407.1 - 0.074 11.9 0.0 0.31 9.9 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Raffinose_syn PF05691.7 ETS77408.1 - 1.5e-29 102.1 0.3 5.4e-25 87.0 0.0 3.3 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 IGR PF09597.5 ETS77408.1 - 0.21 11.5 0.0 0.5 10.3 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif MFS_1 PF07690.11 ETS77409.1 - 1.8e-41 142.0 28.5 1.8e-41 142.0 19.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77409.1 - 5e-10 38.5 21.1 3.3e-09 35.8 14.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 ETS77409.1 - 6.2e-05 21.3 5.7 9.3e-05 20.7 4.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 ETS77409.1 - 0.06 11.3 1.5 0.062 11.3 0.1 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.16 ETS77410.1 - 4.5e-53 179.9 0.0 5.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 ETS77411.1 - 0.003 16.2 0.7 0.0076 14.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Protoglobin PF11563.3 ETS77411.1 - 0.03 13.9 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Protoglobin RTA1 PF04479.8 ETS77412.1 - 2.3e-46 158.1 0.3 2.3e-46 158.1 0.2 1.4 2 0 0 2 2 2 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 ETS77412.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DUF3273 PF11677.3 ETS77412.1 - 0.09 12.0 1.3 2.4 7.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3273) Inositol_P PF00459.20 ETS77412.1 - 0.3 10.3 1.1 0.4 9.9 0.3 1.5 2 0 0 2 2 2 0 Inositol monophosphatase family FA_hydroxylase PF04116.8 ETS77412.1 - 1.7 9.0 8.5 0.22 11.9 0.2 2.8 2 1 1 3 3 3 0 Fatty acid hydroxylase superfamily DUF2236 PF09995.4 ETS77413.1 - 1.4e-26 93.2 0.0 2.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HGTP_anticodon PF03129.15 ETS77413.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain Terpene_synth_C PF03936.11 ETS77414.1 - 1.5e-08 34.2 0.1 2.1e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain F-box PF00646.28 ETS77415.1 - 0.0062 16.1 0.1 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS77415.1 - 0.12 12.1 0.0 0.41 10.4 0.0 2.0 1 0 0 1 1 1 0 F-box-like p450 PF00067.17 ETS77416.1 - 4.2e-69 233.2 0.0 5e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS77417.1 - 3.7e-31 108.1 79.0 2.2e-23 82.5 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS77417.1 - 2.9e-14 52.2 30.6 4.8e-11 41.7 9.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 ETS77417.1 - 1.9e-05 23.4 18.6 1.9e-05 23.4 12.9 3.4 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 ETS77417.1 - 0.56 10.0 14.3 0.04 13.7 1.8 3.5 5 0 0 5 5 5 0 MFS_1 like family Abhydrolase_6 PF12697.2 ETS77418.1 - 2.1e-14 53.9 0.6 4.4e-14 52.9 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77418.1 - 1.1e-06 28.4 0.1 1.6e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS77418.1 - 9.9e-06 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 ETS77418.1 - 7.4e-05 22.4 0.6 0.0003 20.4 0.3 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 ETS77418.1 - 0.045 12.2 0.0 0.07 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0258 PF06789.7 ETS77418.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) adh_short PF00106.20 ETS77419.1 - 6e-15 55.5 0.8 9.8e-15 54.8 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS77419.1 - 3.3e-07 30.1 0.1 5.7e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS77419.1 - 1.8e-05 24.6 0.1 2.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 ETS77419.1 - 8e-05 22.7 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 ETS77419.1 - 0.00055 19.0 0.1 0.00078 18.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydr_30_2 PF14587.1 ETS77419.1 - 0.042 12.7 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Abhydrolase_6 PF12697.2 ETS77420.1 - 4.5e-16 59.4 0.0 5.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77420.1 - 2.7e-11 43.4 0.0 3.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS77420.1 - 2.4e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS77420.1 - 0.0029 17.4 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Imm18 PF15566.1 ETS77420.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 18 HET PF06985.6 ETS77422.1 - 6.7e-31 107.3 1.4 1.3e-29 103.1 0.2 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 ETS77423.1 - 8.5e-23 80.9 0.0 5.8e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS77423.1 - 1.6e-07 30.5 0.4 0.0012 17.8 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS77423.1 - 1.3e-05 24.8 0.1 2.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 ETS77423.1 - 1.4e-05 25.4 0.7 0.00034 20.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77423.1 - 5.3e-05 23.1 0.3 0.00013 21.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS77423.1 - 0.0013 17.4 1.9 0.055 12.0 0.2 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 ETS77423.1 - 0.0018 18.4 0.0 0.0051 16.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77423.1 - 0.0031 16.5 0.1 0.011 14.6 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS77423.1 - 0.0055 15.8 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS77423.1 - 0.013 15.2 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 ETS77423.1 - 0.017 14.1 0.1 0.095 11.7 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 ETS77423.1 - 0.021 13.7 0.1 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 ETS77423.1 - 0.064 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding SE PF08491.5 ETS77423.1 - 0.075 11.8 0.0 0.19 10.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 ETS77423.1 - 0.11 10.9 0.7 0.83 8.0 0.2 2.3 3 0 0 3 3 3 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 ETS77423.1 - 0.13 11.5 0.2 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lactonase PF10282.4 ETS77424.1 - 2.8e-25 89.1 0.1 4e-22 78.7 0.1 2.3 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 ETS77425.1 - 1.2e-09 37.7 0.0 2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase LIX1 PF14954.1 ETS77425.1 - 0.082 11.8 0.3 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Limb expression 1 Lactonase PF10282.4 ETS77426.1 - 2.9e-24 85.7 0.3 3.7e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS77426.1 - 0.0038 16.6 0.1 0.22 10.8 0.0 2.4 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region MerC PF03203.9 ETS77426.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein Tyrosinase PF00264.15 ETS77427.1 - 1.8e-28 100.2 8.7 2.4e-28 99.8 6.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.16 ETS77428.1 - 1.3e-12 47.3 0.1 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase ATP-synt_F PF01990.12 ETS77429.1 - 0.014 15.7 0.0 8.2 6.8 0.0 3.0 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit COesterase PF00135.23 ETS77431.1 - 7.4e-100 335.1 0.0 1.2e-99 334.5 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77431.1 - 5e-10 39.3 0.1 2.3e-09 37.1 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS77431.1 - 1.7e-06 27.4 0.1 4.5e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS77431.1 - 7.5e-06 25.7 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 ETS77432.1 - 4.3e-71 239.8 0.0 5.5e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 ETS77432.1 - 0.092 12.2 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Zn_clus PF00172.13 ETS77433.1 - 1.6e-05 24.7 8.8 3.5e-05 23.6 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS77433.1 - 1.6e-05 23.7 1.4 3e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 ETS77434.1 - 1e-21 77.9 0.0 1.9e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS77434.1 - 7.6e-21 73.8 0.0 5e-15 54.6 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS77434.1 - 9.5e-11 41.1 0.0 3.8e-08 32.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS77434.1 - 6.9e-09 35.8 0.0 3.8e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS77434.1 - 6.9e-06 26.3 0.2 0.77 10.2 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77434.1 - 1.3e-05 25.1 0.0 0.0035 17.3 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS77434.1 - 1.7e-05 23.9 0.7 0.055 12.3 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS77434.1 - 2.7e-05 24.0 0.7 0.076 12.7 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS77434.1 - 5.8e-05 22.3 0.0 0.016 14.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 ETS77434.1 - 0.00042 19.4 0.0 1.1 8.2 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 ETS77434.1 - 0.0013 17.8 0.1 0.56 9.2 0.0 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77434.1 - 0.0023 16.8 0.4 0.086 11.6 0.1 2.7 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.9 ETS77434.1 - 0.0026 16.2 0.0 0.16 10.4 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 ETS77434.1 - 0.0072 15.4 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 ETS77434.1 - 0.028 13.3 0.1 0.069 12.0 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 ETS77434.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 ETS77434.1 - 0.17 10.7 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldo_ket_red PF00248.16 ETS77435.1 - 4.9e-56 189.6 0.0 6.1e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RSD-2 PF07547.8 ETS77435.1 - 0.12 12.5 0.2 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 RSD-2 N-terminal domain GFO_IDH_MocA PF01408.17 ETS77436.1 - 4.4e-14 53.0 0.0 4.5e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS77436.1 - 6.6e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 ETS77437.1 - 5.9e-108 361.3 23.2 6.8e-108 361.1 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77437.1 - 3e-20 72.2 44.7 3.7e-15 55.5 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS77437.1 - 1.9e-08 33.0 10.4 4.7e-06 25.0 2.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 ETS77437.1 - 0.00034 19.4 0.3 0.00034 19.4 0.2 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF791) Ank_2 PF12796.2 ETS77438.1 - 1.1e-66 221.2 17.6 1.3e-17 63.8 0.0 6.7 3 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77438.1 - 7.6e-47 154.8 33.5 2e-07 30.4 0.0 14.3 15 0 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.1 ETS77438.1 - 1.7e-39 132.9 20.3 4.6e-09 36.2 0.0 10.6 6 4 6 12 12 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS77438.1 - 1.9e-37 126.9 16.4 1.7e-07 31.5 0.0 11.4 7 2 4 12 12 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77438.1 - 3.5e-36 119.6 20.9 3.5e-05 23.6 0.0 14.9 16 0 0 16 16 15 7 Ankyrin repeat PGAP1 PF07819.8 ETS77438.1 - 2.6e-05 23.9 0.0 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 ETS77438.1 - 3.8e-05 23.0 0.0 9.2e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 ETS77438.1 - 0.00063 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 ETS77438.1 - 0.00096 18.9 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 ETS77438.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS77438.1 - 0.012 15.1 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 ETS77438.1 - 0.025 13.5 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF726 PF05277.7 ETS77438.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF4013 PF13197.1 ETS77439.1 - 0.0012 18.2 1.9 0.0018 17.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF3309 PF11752.3 ETS77439.1 - 0.011 15.5 0.8 0.011 15.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) EI24 PF07264.6 ETS77439.1 - 0.013 14.8 4.5 0.026 13.9 3.1 1.4 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2976 PF11190.3 ETS77439.1 - 0.051 13.1 3.5 0.082 12.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) HemY_N PF07219.8 ETS77439.1 - 0.076 12.5 2.9 0.36 10.3 0.1 2.9 4 0 0 4 4 4 0 HemY protein N-terminus LRR19-TM PF15176.1 ETS77439.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DAO PF01266.19 ETS77440.1 - 5.2e-46 157.1 0.0 6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77440.1 - 4.2e-09 36.2 0.2 4.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS77440.1 - 2e-05 24.5 0.0 0.00021 21.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS77440.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS77440.1 - 0.00023 20.1 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETS77440.1 - 0.00025 20.2 0.0 0.00046 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 ETS77440.1 - 0.00032 19.6 0.0 0.0006 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 ETS77440.1 - 0.00048 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 ETS77440.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 ETS77440.1 - 0.0025 16.5 0.3 0.015 13.9 0.2 1.9 1 1 0 1 1 1 1 Tryptophan halogenase Shikimate_DH PF01488.15 ETS77440.1 - 0.0054 16.8 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 ETS77440.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Thi4 PF01946.12 ETS77440.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family KR PF08659.5 ETS77440.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Pyr_redox PF00070.22 ETS77440.1 - 0.1 12.9 0.2 0.34 11.3 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS77440.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 ETS77442.1 - 1.3e-123 398.9 51.5 2.2e-14 52.7 1.1 13.6 13 1 0 13 13 13 11 WD domain, G-beta repeat Nup160 PF11715.3 ETS77442.1 - 1e-25 89.9 40.7 0.00082 17.6 0.0 12.5 2 1 10 13 13 13 12 Nucleoporin Nup120/160 NACHT PF05729.7 ETS77442.1 - 2.9e-08 33.5 0.0 7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 ETS77442.1 - 9.4e-08 31.3 0.1 3.6e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 ETS77442.1 - 4.4e-07 30.0 0.4 3e-06 27.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Nucleoporin_N PF08801.6 ETS77442.1 - 6.7e-07 28.4 29.5 0.017 13.8 0.3 5.7 1 1 2 3 3 3 2 Nup133 N terminal like AAA_22 PF13401.1 ETS77442.1 - 8.9e-06 25.8 0.2 0.026 14.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain KAP_NTPase PF07693.9 ETS77442.1 - 0.029 13.3 3.2 2.6 6.9 0.1 2.6 1 1 1 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 ETS77442.1 - 0.066 14.0 0.1 0.27 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETS77442.1 - 0.075 13.2 0.1 0.51 10.5 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 ETS77442.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase FG-GAP_2 PF14312.1 ETS77442.1 - 0.19 11.7 4.4 27 4.8 0.0 4.5 5 0 0 5 5 5 0 FG-GAP repeat HET PF06985.6 ETS77443.1 - 9.7e-30 103.5 1.3 1.6e-29 102.8 0.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gly_transf_sug PF04488.10 ETS77444.1 - 2.1e-08 34.4 0.0 4.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 ETS77444.1 - 0.023 13.1 0.0 0.059 11.8 0.0 1.6 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_S8 PF00082.17 ETS77445.1 - 1.2e-07 31.1 0.0 3.7e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Subtilase family ATPgrasp_YheCD PF14398.1 ETS77446.1 - 0.14 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 YheC/D like ATP-grasp EF-hand_6 PF13405.1 ETS77447.1 - 0.1 12.5 0.2 5.8 7.0 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain RCR PF12273.3 ETS77448.1 - 0.047 14.2 4.7 0.52 10.8 0.2 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Spc7 PF08317.6 ETS77449.1 - 0.0023 16.6 3.9 0.0055 15.4 2.7 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-Q PF13094.1 ETS77449.1 - 0.0032 17.5 2.6 0.0032 17.5 1.8 2.7 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Bacillus_HBL PF05791.6 ETS77449.1 - 0.04 13.2 0.3 0.15 11.3 0.1 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 ETS77449.1 - 0.071 12.9 6.9 0.22 11.3 0.6 3.3 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 ETS77449.1 - 0.34 10.6 0.1 0.34 10.6 0.1 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 ETS77449.1 - 4.6 6.1 12.8 0.031 13.2 2.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AKAP7_NLS PF10469.4 ETS77450.1 - 9.8e-29 100.5 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 ETS77450.1 - 0.00097 18.8 0.1 0.0018 17.9 0.1 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily K_channel_TID PF07941.6 ETS77450.1 - 2.2 8.5 7.4 0.28 11.4 1.2 2.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Hpt PF01627.18 ETS77451.1 - 1.4e-15 57.0 0.1 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Erp_C PF06780.6 ETS77451.1 - 0.013 15.3 2.5 0.016 15.0 1.7 1.1 1 0 0 1 1 1 0 Erp protein C-terminus ATP-synt_F6 PF05511.6 ETS77451.1 - 0.27 11.1 3.0 0.15 11.9 0.4 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF3984 PF13136.1 ETS77452.1 - 1.5e-68 231.4 16.9 1.9e-68 231.0 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Corona_nucleoca PF00937.13 ETS77452.1 - 4.1 6.2 9.5 0.15 11.0 1.5 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein IKI3 PF04762.7 ETS77453.1 - 0 1029.2 0.0 0 1028.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family KOW PF00467.24 ETS77454.1 - 5.9e-05 22.6 0.3 0.00016 21.2 0.2 1.7 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 ETS77455.1 - 1.9e-56 189.9 0.0 2.2e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS77455.1 - 9.9e-16 58.3 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS77455.1 - 3.3e-07 29.7 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETS77455.1 - 0.0012 18.0 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 ETS77455.1 - 0.0016 17.9 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS77455.1 - 0.034 13.2 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 ETS77455.1 - 0.11 12.0 0.0 11 5.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Aa_trans PF01490.13 ETS77456.1 - 5.4e-74 249.1 29.1 6.8e-74 248.7 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NAD_binding_4 PF07993.7 ETS77458.1 - 1.5e-33 115.7 0.0 2.9e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS77458.1 - 2.7e-27 95.2 0.0 4.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS77458.1 - 9.3e-09 35.4 0.0 2.5e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 ETS77458.1 - 4.1e-08 32.9 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Mre11_DNA_bind PF04152.9 ETS77459.1 - 2.6e-50 170.7 1.3 2.6e-50 170.7 0.9 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 ETS77459.1 - 9.4e-13 48.0 1.0 1.6e-12 47.2 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tcp11 PF05794.8 ETS77460.1 - 8e-46 156.6 0.0 8e-46 156.6 0.0 2.3 3 0 0 3 3 3 1 T-complex protein 11 V_ATPase_I PF01496.14 ETS77460.1 - 0.47 8.2 4.5 0.68 7.7 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2458 PF10454.4 ETS77460.1 - 4.3 7.2 13.5 1.4 8.7 3.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2458) Y_phosphatase PF00102.22 ETS77461.1 - 6.8e-59 199.0 0.0 1e-50 172.2 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 ETS77461.1 - 4.1e-12 46.4 0.0 2e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 ETS77461.1 - 0.018 15.3 0.2 0.066 13.4 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 ETS77461.1 - 0.076 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.24 ETS77462.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS77462.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS77462.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETS77462.1 - 3.2e-06 27.2 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS77462.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS77462.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS77462.1 - 7.7e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS77462.1 - 0.00013 21.6 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 ETS77462.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 ETS77462.1 - 0.0009 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 ETS77462.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS77462.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETS77462.1 - 0.0022 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 ETS77462.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 ETS77462.1 - 0.0038 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS77462.1 - 0.0068 16.7 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETS77462.1 - 0.0069 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 ETS77462.1 - 0.0075 15.4 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 ETS77462.1 - 0.017 14.5 0.1 0.075 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 ETS77462.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 ETS77462.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 ETS77462.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 ETS77462.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS77462.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 ETS77462.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 ETS77462.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 ETS77462.1 - 0.05 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 ETS77462.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 ETS77462.1 - 0.099 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 ETS77462.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Na_Ca_ex PF01699.19 ETS77463.1 - 6.1e-31 106.8 31.1 8.2e-18 64.3 7.2 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 ETS77463.1 - 5.1e-14 52.4 11.6 5.1e-14 52.4 8.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF307) YoqO PF14037.1 ETS77463.1 - 0.69 10.0 10.6 5.4 7.1 0.4 3.3 3 0 0 3 3 3 0 YoqO-like protein CTP_transf_2 PF01467.21 ETS77464.1 - 0.031 14.3 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase UL73_N PF12522.3 ETS77464.1 - 3.5 7.2 12.8 11 5.6 8.9 1.9 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal APC10 PF03256.11 ETS77465.1 - 9.6e-48 162.3 0.0 1.4e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 ETS77465.1 - 2.7 6.3 6.7 3.6 5.9 4.7 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_M1 PF01433.15 ETS77466.1 - 9.7e-135 449.6 0.4 1.5e-134 448.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 ETS77466.1 - 2.3e-67 227.5 0.1 1.3e-66 225.0 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 ETS77466.1 - 9.7e-18 64.4 1.8 4.1e-17 62.4 0.1 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 ETS77466.1 - 0.0044 16.8 0.0 0.098 12.4 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function DUF45 TMF_TATA_bd PF12325.3 ETS77467.1 - 0.013 15.2 2.5 0.013 15.2 1.7 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2422 PF10337.4 ETS77467.1 - 0.045 12.5 1.1 0.09 11.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) API5 PF05918.6 ETS77467.1 - 2.2 6.6 11.2 0.5 8.8 5.1 1.9 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Enkurin PF13864.1 ETS77467.1 - 9.4 6.5 13.3 0.94 9.7 0.4 3.4 2 1 2 4 4 4 0 Calmodulin-binding CBFD_NFYB_HMF PF00808.18 ETS77468.1 - 0.0001 22.3 0.2 0.00013 21.9 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone JmjC PF02373.17 ETS77469.1 - 5.1e-36 123.3 0.4 1.5e-35 121.8 0.3 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 ETS77469.1 - 1.1e-20 73.7 4.2 1.8e-20 72.9 2.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS77469.1 - 2.7e-20 72.3 3.9 5.8e-20 71.2 2.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 ETS77469.1 - 1.4e-13 50.0 0.8 2.7e-13 49.1 0.6 1.5 1 0 0 1 1 1 1 jmjN domain OB_NTP_bind PF07717.11 ETS77470.1 - 1.7e-27 95.5 0.1 6.9e-27 93.5 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS77470.1 - 1.6e-23 82.6 0.0 4.3e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS77470.1 - 1.2e-10 41.0 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS77470.1 - 1.2e-07 31.4 0.2 3.6e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS77470.1 - 2.9e-07 30.6 0.0 9.2e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 ETS77470.1 - 0.00014 21.3 0.1 0.00049 19.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 ETS77470.1 - 0.0014 17.5 0.0 0.0032 16.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 ETS77470.1 - 0.0099 15.7 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 ETS77470.1 - 0.02 14.6 0.2 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Response_reg PF00072.19 ETS77470.1 - 0.027 14.4 0.3 0.34 10.9 0.1 2.6 2 0 0 2 2 2 0 Response regulator receiver domain AAA_30 PF13604.1 ETS77470.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS77470.1 - 0.12 12.5 1.1 1.4 9.1 0.8 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2183 PF09949.4 ETS77471.1 - 7.5e-20 70.7 0.1 2.5e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Prefoldin_2 PF01920.15 ETS77472.1 - 5.9e-25 87.0 6.1 7.2e-25 86.7 4.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit THOC7 PF05615.8 ETS77472.1 - 0.014 15.6 7.6 0.047 13.9 0.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3496 PF12001.3 ETS77472.1 - 0.017 15.3 1.4 0.017 15.3 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) HVSL PF09749.4 ETS77472.1 - 0.039 12.9 0.2 0.053 12.5 0.1 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein FTA4 PF13093.1 ETS77472.1 - 0.044 13.2 2.3 0.052 12.9 1.6 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Syntaxin-6_N PF09177.6 ETS77472.1 - 0.1 12.9 3.1 7.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AAA_23 PF13476.1 ETS77472.1 - 0.5 10.6 5.0 0.65 10.2 3.5 1.1 1 0 0 1 1 1 0 AAA domain XhlA PF10779.4 ETS77472.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 Haemolysin XhlA Prefoldin PF02996.12 ETS77472.1 - 3.8 7.1 8.5 0.42 10.2 0.6 2.1 1 1 0 2 2 2 0 Prefoldin subunit PRMT5 PF05185.11 ETS77473.1 - 2.5e-167 557.3 0.0 3e-167 557.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase LSM PF01423.17 ETS77474.1 - 2.8e-19 68.4 0.1 3.2e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 ETS77475.1 - 5.8e-43 146.1 0.6 6.7e-43 145.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-DNL PF05180.7 ETS77475.1 - 0.012 15.2 0.8 4.8 6.9 0.1 2.4 2 0 0 2 2 2 0 DNL zinc finger PHD PF00628.24 ETS77475.1 - 0.026 14.2 0.7 0.053 13.2 0.5 1.6 1 0 0 1 1 1 0 PHD-finger Terminase_GpA PF05876.7 ETS77475.1 - 0.092 11.0 1.0 0.12 10.6 0.7 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF3716 PF12511.3 ETS77475.1 - 0.1 12.2 2.8 0.19 11.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cas_CXXC_CXXC PF09706.5 ETS77475.1 - 0.11 12.7 4.1 0.18 11.9 1.9 2.0 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) Zn_Tnp_IS1595 PF12760.2 ETS77475.1 - 4.6 7.1 6.5 27 4.6 4.5 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain GDPD PF03009.12 ETS77477.1 - 4.8e-68 229.4 0.0 1e-67 228.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 ETS77477.1 - 2.8e-33 114.1 1.7 6.8e-11 42.3 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS77477.1 - 1.4e-30 105.0 3.1 2.2e-10 40.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 ETS77477.1 - 1.8e-30 106.6 4.8 5.4e-18 65.7 1.7 3.4 2 1 0 2 2 2 2 SPX domain Ank PF00023.25 ETS77477.1 - 6e-26 88.9 9.2 3e-06 26.7 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 ETS77477.1 - 6e-25 86.7 1.2 2.3e-08 33.9 0.0 6.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77477.1 - 7.5e-17 59.7 3.0 0.00064 19.7 0.0 7.2 6 0 0 6 6 6 2 Ankyrin repeat DUF1826 PF08856.6 ETS77477.1 - 0.072 12.8 0.2 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) DUF1978 PF09321.5 ETS77477.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Peptidase_M41 PF01434.13 ETS77478.1 - 1.6e-66 223.8 1.5 2.5e-66 223.1 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 ETS77478.1 - 7.3e-43 145.9 0.0 1.8e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS77478.1 - 5.1e-06 26.2 0.0 2.7e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS77478.1 - 1.8e-05 24.9 0.7 0.0056 16.8 0.1 3.5 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 ETS77478.1 - 2.1e-05 25.2 0.0 6.9e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS77478.1 - 2.2e-05 24.5 3.6 0.0019 18.2 0.1 4.0 4 1 1 5 5 5 1 AAA ATPase domain TIP49 PF06068.8 ETS77478.1 - 4.3e-05 22.4 0.0 8.1e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 ETS77478.1 - 8.5e-05 21.7 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 ETS77478.1 - 0.0013 18.5 0.0 0.0066 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS77478.1 - 0.0015 18.2 0.5 0.0056 16.4 0.4 2.0 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 ETS77478.1 - 0.0023 17.3 0.4 0.0067 15.8 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 ETS77478.1 - 0.0033 16.8 1.0 0.067 12.5 0.2 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS77478.1 - 0.0077 15.3 0.5 0.022 13.8 0.2 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 ETS77478.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS77478.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS77478.1 - 0.02 14.0 0.3 0.044 12.9 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 ETS77478.1 - 0.069 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 ETS77478.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain SpoU_sub_bind PF08032.7 ETS77478.1 - 0.11 12.7 0.2 13 6.0 0.0 3.2 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding PhoH PF02562.11 ETS77478.1 - 0.14 11.3 0.2 0.28 10.3 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 ETS77478.1 - 0.2 11.3 2.5 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Ufd2P_core PF10408.4 ETS77479.1 - 8.2e-187 622.2 6.5 1e-186 621.9 4.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 ETS77479.1 - 1.2e-21 76.3 0.7 4.5e-21 74.6 0.5 2.0 1 0 0 1 1 1 1 U-box domain PEP-utilisers_N PF05524.8 ETS77479.1 - 0.6 9.9 4.8 5.7 6.7 0.1 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Epimerase PF01370.16 ETS77481.1 - 3.1e-19 69.3 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS77481.1 - 2.5e-13 50.4 0.0 5e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS77481.1 - 2.6e-13 49.3 0.0 3.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS77481.1 - 9e-10 37.8 0.0 6e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS77481.1 - 8e-08 32.3 0.1 1.8e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS77481.1 - 4.9e-05 22.3 0.0 7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS77481.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 ETS77481.1 - 0.0018 18.6 0.0 0.0064 16.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 ETS77481.1 - 0.0033 16.6 0.0 0.0083 15.4 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 ETS77481.1 - 0.0045 16.0 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 ETS77481.1 - 0.046 12.6 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain zf-C2H2 PF00096.21 ETS77482.1 - 1.6e-20 72.0 29.5 1.1e-05 25.4 1.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS77482.1 - 2.8e-20 71.5 27.2 5.4e-08 32.7 0.4 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS77482.1 - 4.1e-10 39.2 26.1 0.0017 18.5 0.9 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.13 ETS77482.1 - 0.0072 16.6 15.0 0.051 13.9 1.9 3.5 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 ETS77482.1 - 0.012 15.7 12.4 0.8 9.9 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS77482.1 - 0.036 14.2 0.6 0.036 14.2 0.4 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 ETS77482.1 - 0.046 13.3 0.7 2.3 7.9 0.1 2.7 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger CHORD PF04968.7 ETS77482.1 - 4.1 7.7 16.1 3.8 7.8 0.2 4.3 1 1 3 4 4 4 0 CHORD Glyco_trans_2_3 PF13632.1 ETS77485.1 - 0.023 14.3 0.1 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DOCK-C2 PF14429.1 ETS77486.1 - 1e-21 77.4 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 ETS77486.1 - 6.4e-09 35.3 0.2 1.6e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 ETS77486.1 - 6.4e-05 22.2 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS77486.1 - 0.0001 21.7 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain VTC PF09359.5 ETS77487.1 - 2e-94 315.7 3.0 4.3e-94 314.6 2.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 ETS77487.1 - 2.3e-19 70.2 18.4 2.4e-09 37.4 4.1 4.2 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 ETS77487.1 - 8e-10 38.7 1.7 8e-10 38.7 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LUC7 PF03194.10 ETS77487.1 - 0.11 11.9 7.2 0.061 12.8 0.6 2.8 3 0 0 3 3 3 0 LUC7 N_terminus SNARE PF05739.14 ETS77490.1 - 2.2e-10 40.0 4.6 3e-10 39.6 3.2 1.2 1 0 0 1 1 1 1 SNARE domain Apc15p PF05841.6 ETS77491.1 - 8e-21 75.0 7.8 8e-21 75.0 5.4 2.5 3 0 0 3 3 3 1 Apc15p protein Rrp15p PF07890.7 ETS77491.1 - 2.8 7.9 7.6 0.47 10.5 0.1 2.5 3 0 0 3 3 3 0 Rrp15p Glu_synthase PF01645.12 ETS77492.1 - 4.1e-160 532.6 0.0 6.5e-160 532.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 ETS77492.1 - 3.4e-141 470.1 0.0 4.6e-141 469.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 ETS77492.1 - 1.7e-116 388.5 0.0 2.9e-116 387.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 ETS77492.1 - 6.3e-68 227.7 3.3 1.2e-67 226.8 2.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 ETS77492.1 - 8.1e-23 80.1 0.1 1.9e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 ETS77492.1 - 2.3e-16 60.2 0.0 1.2e-15 57.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS77492.1 - 2.6e-10 40.6 0.4 0.00034 20.7 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77492.1 - 8.7e-08 32.0 0.0 3.3e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS77492.1 - 1e-06 29.0 0.1 0.00098 19.4 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS77492.1 - 1.4e-05 24.3 0.4 2.9e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 ETS77492.1 - 0.00023 19.7 0.1 0.00023 19.7 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS77492.1 - 0.00031 19.7 1.0 0.00079 18.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77492.1 - 0.00034 19.5 0.1 0.0023 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 ETS77492.1 - 0.0005 19.6 0.1 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 ETS77492.1 - 0.00069 19.8 1.0 1 9.6 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 ETS77492.1 - 0.0018 17.4 0.1 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS77492.1 - 0.0058 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS77492.1 - 0.014 14.4 0.1 0.037 13.1 0.1 1.7 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 ETS77492.1 - 0.031 13.9 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 ETS77492.1 - 0.032 13.7 0.2 0.77 9.2 0.0 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family GIDA PF01134.17 ETS77492.1 - 0.057 12.2 1.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FMN_dh PF01070.13 ETS77492.1 - 0.063 12.1 0.6 0.4 9.4 0.4 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.15 ETS77492.1 - 0.15 12.1 0.3 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Relaxase PF03432.9 ETS77492.1 - 0.18 11.1 1.4 0.4 10.0 0.9 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain FMO-like PF00743.14 ETS77492.1 - 0.79 7.8 0.1 32 2.5 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Arm PF00514.18 ETS77493.1 - 3e-07 30.0 27.1 0.66 9.8 0.7 9.5 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS77493.1 - 2.4e-06 27.7 22.8 0.0053 17.0 0.5 7.3 6 2 1 7 7 7 3 HEAT repeats HEAT PF02985.17 ETS77493.1 - 0.036 14.1 22.5 3.6 7.9 0.1 8.6 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.1 ETS77493.1 - 0.046 14.2 18.9 1.8 9.1 0.3 6.7 6 1 1 7 7 7 0 HEAT-like repeat Cyclin PF08613.6 ETS77494.1 - 2.4e-28 99.4 0.1 4.9e-28 98.4 0.1 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS77494.1 - 0.00029 20.4 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.5 ETS77496.1 - 3.5e-15 54.9 0.7 3.5e-15 54.9 0.5 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ Velvet PF11754.3 ETS77497.1 - 2.1e-62 210.3 0.0 5e-62 209.1 0.0 1.6 2 0 0 2 2 2 1 Velvet factor Pol_alpha_B_N PF08418.5 ETS77497.1 - 4.3 6.8 9.3 17 4.8 6.5 1.9 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ank PF00023.25 ETS77499.1 - 4.2e-16 57.8 0.1 9.7e-09 34.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETS77499.1 - 1.6e-15 56.7 0.0 9.6e-13 47.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS77499.1 - 8.9e-15 54.8 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 ETS77499.1 - 4.7e-13 48.9 0.7 4.7e-13 48.9 0.5 2.7 3 0 0 3 3 3 1 IPT/TIG domain Ank_3 PF13606.1 ETS77499.1 - 2.4e-11 42.7 0.0 2e-05 24.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETS77499.1 - 1e-10 41.8 0.0 1.4e-06 28.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Na_H_Exchanger PF00999.16 ETS77500.1 - 3.9e-40 137.5 20.0 5.2e-40 137.1 13.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cauli_VI PF01693.11 ETS77501.1 - 1.9e-32 110.9 6.9 2.9e-18 65.6 0.1 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 ETS77501.1 - 4.8e-27 94.9 0.0 8.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 RNase H dCMP_cyt_deam_1 PF00383.17 ETS77502.1 - 2.5e-09 36.6 0.0 7e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 ETS77502.1 - 0.031 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase 6PF2K PF01591.13 ETS77503.1 - 5e-65 218.6 0.0 1.4e-44 151.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETS77503.1 - 6.6e-24 84.7 0.2 3.4e-23 82.4 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 ETS77503.1 - 3e-05 23.9 0.1 0.00046 20.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS77503.1 - 0.01 16.6 0.0 0.048 14.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 ETS77503.1 - 0.038 13.1 0.0 0.084 12.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HATPase_c PF02518.21 ETS77504.1 - 7e-24 83.6 0.4 1.3e-23 82.7 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS77504.1 - 7.7e-21 73.8 0.1 2.1e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 ETS77504.1 - 1.1e-20 73.6 0.0 7.5e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 ETS77504.1 - 1.8e-18 66.4 3.6 5.3e-10 39.2 0.6 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 ETS77504.1 - 7e-15 55.2 0.0 7.1e-08 32.7 0.0 3.2 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 ETS77504.1 - 1.4e-07 31.4 0.1 3.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 ETS77504.1 - 6.1e-06 26.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 ETS77504.1 - 0.052 13.4 0.0 0.96 9.4 0.0 2.5 2 0 0 2 2 2 0 PAS domain DUF1445 PF07286.7 ETS77505.1 - 1.5e-51 173.8 0.0 3.2e-51 172.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.13 ETS77506.1 - 6.3e-28 97.3 0.0 1.1e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DIL PF01843.14 ETS77507.1 - 7.9e-18 64.2 1.8 8.1e-16 57.8 1.3 2.5 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 ETS77507.1 - 9.8e-18 64.2 0.3 2.4e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77507.1 - 2.7e-16 58.4 1.1 1.3e-06 27.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETS77507.1 - 2.6e-12 46.8 1.5 2.5e-05 24.6 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77507.1 - 2.6e-11 43.3 0.4 8.6e-08 32.1 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77507.1 - 5.6e-08 32.2 0.1 0.022 14.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Allantoicase PF03561.10 ETS77508.1 - 1.1e-106 352.8 0.0 3.9e-57 191.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 ETS77509.1 - 7.7e-20 71.1 5.2 7.7e-20 71.1 3.6 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 ETS77509.1 - 0.0015 17.8 13.8 0.005 16.1 4.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF998) PepSY_TM_1 PF13172.1 ETS77509.1 - 0.32 10.7 0.2 0.32 10.7 0.1 4.2 5 0 0 5 5 5 0 PepSY-associated TM helix DUF4079 PF13301.1 ETS77509.1 - 4 7.4 15.7 0.78 9.7 3.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) RabGAP-TBC PF00566.13 ETS77510.1 - 2.6e-36 125.1 0.1 4.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2722 PF10846.3 ETS77511.1 - 0.00086 18.4 0.0 0.00086 18.4 0.0 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) Spindle_Spc25 PF08234.7 ETS77512.1 - 0.00066 19.6 0.1 0.058 13.4 0.1 2.7 2 0 0 2 2 2 2 Chromosome segregation protein Spc25 AAA PF00004.24 ETS77513.1 - 3.7e-18 65.9 0.0 3.4e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS77513.1 - 1e-05 25.6 0.4 9.4e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS77513.1 - 0.00028 20.9 1.1 0.013 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 ETS77513.1 - 0.002 18.0 0.1 0.4 10.5 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS77513.1 - 0.0098 15.6 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 ETS77513.1 - 0.019 13.8 0.2 0.042 12.6 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 ETS77513.1 - 0.036 13.8 0.1 0.081 12.6 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 ETS77513.1 - 0.038 13.0 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS77513.1 - 0.046 14.5 0.1 0.36 11.6 0.0 2.7 4 0 0 4 4 2 0 AAA domain AAA_33 PF13671.1 ETS77513.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS77513.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HATPase_c PF02518.21 ETS77514.1 - 1.1e-27 95.8 0.0 2.7e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS77514.1 - 3.5e-20 72.0 0.2 8.3e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 ETS77514.1 - 3.1e-19 68.7 0.2 1.1e-18 66.9 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 ETS77514.1 - 5.9e-12 45.9 0.3 3.9e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 ETS77514.1 - 4.8e-08 33.6 0.0 1.3e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 ETS77514.1 - 9.7e-07 28.1 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 ETS77514.1 - 0.0001 22.3 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 ETS77514.1 - 0.00019 20.5 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GAF PF01590.21 ETS77514.1 - 0.0005 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 ETS77514.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.7 ETS77514.1 - 0.011 15.3 0.2 4.7 6.8 0.0 3.0 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.17 ETS77514.1 - 0.036 12.9 0.2 0.092 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 ETS77514.1 - 0.1 11.3 0.1 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NAD_binding_8 PF13450.1 ETS77515.1 - 1e-09 38.2 0.1 2.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS77515.1 - 1.8e-06 27.3 0.0 3.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 ETS77515.1 - 7.2e-05 22.9 0.1 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77515.1 - 0.0024 17.7 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS77515.1 - 0.0099 14.9 0.2 0.021 13.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS77515.1 - 0.016 13.7 0.1 0.031 12.7 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 ETS77515.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 ETS77515.1 - 0.036 13.1 0.1 0.076 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 ETS77515.1 - 0.11 12.3 0.7 1 9.1 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 ETS77515.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS77515.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3907 PF13047.1 ETS77515.1 - 0.26 10.9 0.8 0.46 10.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) TPT PF03151.11 ETS77516.1 - 1.2e-28 99.7 12.3 1.2e-28 99.7 8.5 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETS77516.1 - 1.4 7.8 23.6 34 3.2 16.4 2.1 1 1 0 1 1 1 0 UAA transporter family Ribosomal_L27e PF01777.13 ETS77517.1 - 5.6e-37 125.7 4.7 7.3e-37 125.3 3.3 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 ETS77517.1 - 0.00073 19.1 0.7 0.0018 17.9 0.5 1.7 1 0 0 1 1 1 1 KOW motif TPR_11 PF13414.1 ETS77518.1 - 0.0019 17.8 0.6 0.044 13.4 0.2 2.7 1 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 ETS77518.1 - 0.13 12.5 1.0 1 9.7 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 ETS77519.1 - 5.9e-25 87.6 0.8 6.1e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 ETS77519.1 - 5.1e-14 52.2 0.4 7.2e-07 29.2 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS77519.1 - 3.8e-10 40.3 0.1 1.3e-05 25.7 0.1 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 ETS77519.1 - 3.3e-06 27.1 0.1 0.15 11.9 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 ETS77519.1 - 0.013 15.4 0.3 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.9 ETS77520.1 - 4e-74 248.4 0.0 5.2e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 ETS77520.1 - 3.1e-18 65.4 9.8 3.1e-18 65.4 6.8 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 ETS77520.1 - 5.1e-09 36.4 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyoxalase_4 PF13669.1 ETS77521.1 - 5.4e-15 55.3 0.0 7.4e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pec_lyase_C PF00544.14 ETS77522.1 - 4.6e-38 130.7 4.1 7.7e-38 129.9 2.9 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 ETS77522.1 - 0.0004 20.1 13.2 0.0012 18.5 6.1 2.7 2 1 0 2 2 2 1 Right handed beta helix region Choline_transpo PF04515.7 ETS77523.1 - 4.3e-16 58.5 27.0 3.5e-14 52.2 9.3 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 ETS77524.1 - 6.1e-50 168.7 0.1 8.5e-49 165.0 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETS77524.1 - 9.3e-17 61.6 0.0 1.8e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS77524.1 - 3.8e-11 42.5 0.0 1.4e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS77524.1 - 4.4e-07 29.5 0.0 1.2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS77524.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS77524.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 ETS77524.1 - 0.0058 16.1 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 ETS77524.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS77524.1 - 0.046 13.1 0.1 4.2 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ETS77524.1 - 0.053 12.2 0.2 0.11 11.2 0.1 1.5 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 ETS77524.1 - 0.078 12.9 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 ETS77524.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 ETS77524.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETS77524.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter PMT PF02366.13 ETS77525.1 - 1.3e-76 257.1 16.8 1.3e-76 257.1 11.6 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS77525.1 - 8.3e-38 129.8 0.1 1.4e-37 129.1 0.1 1.4 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 ETS77526.1 - 1.1e-101 340.7 12.1 1.2e-101 340.4 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77526.1 - 4.2e-26 91.5 21.4 1.2e-25 89.9 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 ETS77526.1 - 0.0041 15.8 0.2 0.0075 15.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Chs3p PF12271.3 ETS77527.1 - 1.6e-105 352.3 8.2 1.8e-105 352.1 5.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit adh_short PF00106.20 ETS77528.1 - 7.5e-13 48.7 0.0 2.5e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS77528.1 - 0.0061 16.3 0.2 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 ETS77528.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS77528.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WW PF00397.21 ETS77529.1 - 7.8e-09 35.2 5.3 1.5e-08 34.3 3.7 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 ETS77530.1 - 1e-25 89.9 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Cys_Met_Meta_PP PF01053.15 ETS77531.1 - 1.1e-146 488.0 0.0 1.3e-146 487.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS77531.1 - 4.1e-12 45.8 0.2 7.8e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 ETS77531.1 - 2.7e-10 39.7 0.0 4.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS77531.1 - 3.3e-08 33.0 0.0 5.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 ETS77531.1 - 8.6e-08 31.3 0.3 1.6e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 ETS77531.1 - 0.0016 16.7 0.1 0.0022 16.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 ETS77531.1 - 0.0028 16.4 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_60s PF00428.14 ETS77531.1 - 0.5 10.7 7.0 7.2 7.0 0.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein MARVEL PF01284.18 ETS77532.1 - 1.3e-21 76.8 15.3 1.6e-21 76.6 10.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain MadM PF03818.8 ETS77532.1 - 0.22 11.0 3.4 4.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit AMP-binding PF00501.23 ETS77533.1 - 1e-81 274.5 0.0 1.2e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 ETS77534.1 - 1.3e-09 37.5 12.6 0.06 13.2 0.2 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat RRM_1 PF00076.17 ETS77535.1 - 4.5e-07 29.3 0.0 9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS77535.1 - 1.5e-06 27.9 0.1 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS77535.1 - 8.2e-06 25.7 0.2 0.00014 21.7 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 ETS77535.1 - 8.3e-05 22.7 0.1 0.00039 20.5 0.1 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. PAT1 PF09770.4 ETS77535.1 - 0.46 8.6 19.7 0.69 8.0 13.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 ETS77535.1 - 7.6 6.5 10.0 1.8 8.5 2.7 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Citrate_synt PF00285.16 ETS77536.1 - 1e-100 336.9 0.0 1.8e-100 336.1 0.0 1.4 2 0 0 2 2 2 1 Citrate synthase Eclosion PF04736.7 ETS77536.1 - 0.048 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 ETS77537.1 - 5e-29 99.8 5.1 1.3e-12 47.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 ETS77538.1 - 3.5e-63 212.7 5.7 8.6e-63 211.4 4.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS77538.1 - 2.5e-23 83.6 0.0 5.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS77538.1 - 3.2e-12 46.9 0.0 9.3e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS77538.1 - 2.1e-10 39.9 0.0 4.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS77538.1 - 0.008 15.7 0.1 0.008 15.7 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OAD_gamma PF04277.8 ETS77538.1 - 7.2 7.0 7.9 22 5.4 0.5 3.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ABM PF03992.11 ETS77539.1 - 0.00066 19.6 0.1 0.00093 19.1 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3733 PF12534.3 ETS77539.1 - 0.073 12.3 0.4 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 WD40 PF00400.27 ETS77540.1 - 0.094 12.6 2.6 3.3 7.7 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat FGGY_C PF02782.11 ETS77542.1 - 6.4e-51 172.7 1.5 1e-50 172.1 1.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETS77542.1 - 1.3e-24 86.8 0.4 2e-21 76.4 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 ETS77542.1 - 0.029 13.7 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Hexokinase Nic96 PF04097.9 ETS77543.1 - 1.5e-204 680.6 0.1 1.9e-204 680.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 ETS77543.1 - 3e-15 56.4 99.0 2.5e-09 37.3 32.9 4.0 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF3425 PF11905.3 ETS77544.1 - 4.5e-23 81.6 2.0 1e-22 80.4 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS77544.1 - 0.00093 19.1 7.0 0.0012 18.7 3.9 1.8 1 1 0 1 1 1 1 bZIP transcription factor Macoilin PF09726.4 ETS77544.1 - 0.69 8.1 12.9 2 6.6 8.5 1.9 1 1 1 2 2 2 0 Transmembrane protein CFEM PF05730.6 ETS77545.1 - 4.4e-09 36.0 7.6 1.3e-08 34.5 5.2 1.8 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.10 ETS77546.1 - 1e-222 740.5 0.0 1.5e-222 739.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 ETS77546.1 - 3.4e-24 84.4 0.0 2.3e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 ETS77546.1 - 1.5e-17 63.8 0.0 9.2e-17 61.2 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain MMR_HSR1_C PF08438.5 ETS77546.1 - 0.035 14.3 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TatD_DNase PF01026.16 ETS77547.1 - 1.9e-43 148.5 0.0 4.2e-42 144.1 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 ETS77547.1 - 0.017 14.7 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase CENP-N PF05238.8 ETS77548.1 - 2.7e-121 405.4 0.0 3.6e-121 404.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 ETS77550.1 - 1.4e-11 43.9 13.9 2.1e-11 43.4 9.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS77550.1 - 2.1e-06 27.5 10.1 3.4e-06 26.9 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 ETS77550.1 - 0.0027 17.4 0.1 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein CCDC144C PF14915.1 ETS77550.1 - 0.0035 16.2 4.1 0.0059 15.5 2.8 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region XhlA PF10779.4 ETS77550.1 - 0.011 15.5 3.2 0.019 14.8 2.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.13 ETS77550.1 - 0.055 13.4 0.8 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 ETS77550.1 - 0.081 13.2 6.8 0.17 12.2 4.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 ETS77550.1 - 0.1 12.1 0.7 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 IncA protein Milton PF12448.3 ETS77550.1 - 0.11 12.6 1.8 0.15 12.2 1.3 1.3 1 0 0 1 1 1 0 Kinesin associated protein Fzo_mitofusin PF04799.8 ETS77550.1 - 0.13 11.5 0.3 0.18 11.1 0.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region Phlebovirus_NSM PF07246.6 ETS77550.1 - 0.19 10.8 3.2 0.25 10.4 2.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF342 PF03961.8 ETS77550.1 - 0.94 7.8 4.9 1.7 6.9 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF972 PF06156.8 ETS77550.1 - 0.98 9.7 4.5 0.87 9.9 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 ETS77550.1 - 1 8.2 7.1 1.3 7.9 4.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HDV_ag PF01517.13 ETS77550.1 - 2.7 7.6 11.3 0.98 9.0 3.1 2.3 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen PBP PF01161.15 ETS77551.1 - 4.7e-17 62.1 0.0 7.2e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein BRO1 PF03097.13 ETS77552.1 - 2.7e-116 388.4 0.4 2.7e-116 388.4 0.3 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 ETS77552.1 - 6e-77 258.5 6.1 6e-77 258.5 4.2 2.4 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV CCER1 PF15482.1 ETS77552.1 - 0.17 11.4 8.0 0.029 14.0 2.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Herpes_DNAp_acc PF04929.7 ETS77552.1 - 2.1 7.2 4.5 4 6.2 3.1 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Patatin PF01734.17 ETS77553.1 - 7.7e-20 71.6 0.0 1.4e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 ETS77553.1 - 5.7e-05 23.0 25.6 0.0069 16.3 7.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 ETS77553.1 - 0.0031 17.8 0.0 0.0093 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETS77553.1 - 0.0073 15.5 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS77553.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS77553.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 ETS77553.1 - 0.27 10.9 21.8 0.51 10.0 5.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pro_CA PF00484.14 ETS77554.1 - 2.9e-50 170.2 0.0 3.8e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Peripla_BP_6 PF13458.1 ETS77554.1 - 0.17 11.2 0.0 0.58 9.4 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein DUF604 PF04646.7 ETS77555.1 - 1.9e-08 33.8 0.1 3.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 ETS77555.1 - 1.6e-07 30.7 0.0 3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Rep-A_N PF04057.7 ETS77556.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Roughex PF06020.6 ETS77556.1 - 0.12 11.0 3.3 0.15 10.7 1.8 1.4 1 1 0 1 1 1 0 Drosophila roughex protein Transferase PF02458.10 ETS77557.1 - 1e-11 43.9 0.3 8.6e-09 34.3 0.0 3.1 2 1 0 2 2 2 2 Transferase family Exo_endo_phos PF03372.18 ETS77558.1 - 3.7e-12 46.7 1.4 4.9e-12 46.3 0.5 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETS77558.1 - 0.023 14.2 0.0 0.51 9.9 0.0 2.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Grp1_Fun34_YaaH PF01184.14 ETS77559.1 - 2.4e-17 62.9 11.1 3.6e-17 62.3 7.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bax1-I PF01027.15 ETS77559.1 - 0.0079 15.8 8.6 0.0079 15.8 5.9 2.2 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 P21-Arc PF04062.9 ETS77561.1 - 5.3e-75 251.0 0.0 5.9e-75 250.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 ETS77561.1 - 0.0073 16.2 1.5 0.017 15.1 1.0 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide Gcd10p PF04189.8 ETS77562.1 - 2.2e-70 237.1 0.0 3.6e-69 233.1 0.0 2.5 1 1 0 1 1 1 1 Gcd10p family Tcp11 PF05794.8 ETS77563.1 - 2.9e-87 293.2 0.8 9.4e-81 271.7 0.6 2.1 1 1 1 2 2 2 2 T-complex protein 11 Peptidase_M75 PF09375.5 ETS77563.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Imelysin TFIID-18kDa PF02269.11 ETS77564.1 - 1.3e-19 69.7 0.0 2e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 ETS77564.1 - 0.033 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SecG PF03840.9 ETS77564.1 - 1.6 8.5 3.7 0.62 9.8 0.9 1.5 2 0 0 2 2 2 0 Preprotein translocase SecG subunit EamA PF00892.15 ETS77565.1 - 1.2e-21 77.0 12.5 3.4e-12 46.5 0.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 ETS77565.1 - 3.2e-05 24.0 20.5 7.5e-05 22.9 1.3 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Formyl_trans_N PF00551.14 ETS77567.1 - 2.6e-36 124.8 0.1 3e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Band_7 PF01145.20 ETS77568.1 - 1.3e-13 51.2 0.1 1.3e-13 51.2 0.1 3.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Cutinase PF01083.17 ETS77569.1 - 3.9e-42 143.9 5.0 4.9e-42 143.6 3.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS77569.1 - 0.00044 19.7 0.1 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 ETS77569.1 - 0.0037 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.6 ETS77569.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF3089 PF11288.3 ETS77569.1 - 0.016 14.4 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 ETS77569.1 - 0.019 14.5 0.2 0.028 14.0 0.2 1.4 1 1 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 ETS77569.1 - 0.072 12.4 0.2 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TIP49 PF06068.8 ETS77570.1 - 1.5e-186 619.9 0.2 1.7e-186 619.7 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 ETS77570.1 - 1.1e-10 41.7 0.2 6e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS77570.1 - 6.5e-08 31.9 2.5 2.3e-05 23.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS77570.1 - 8.5e-05 22.2 0.2 0.00032 20.3 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS77570.1 - 0.00012 22.2 0.3 0.65 10.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS77570.1 - 0.00016 21.6 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 ETS77570.1 - 0.00024 21.0 0.1 0.0005 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS77570.1 - 0.0012 18.6 0.2 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETS77570.1 - 0.0012 18.3 0.0 0.005 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETS77570.1 - 0.0043 16.4 0.3 0.011 15.2 0.2 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETS77570.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS77570.1 - 0.016 14.3 0.1 0.59 9.2 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 ETS77570.1 - 0.018 14.0 0.1 0.049 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 ETS77570.1 - 0.02 13.9 0.3 0.052 12.6 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 ETS77570.1 - 0.045 13.2 0.1 2.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain DnaB_C PF03796.10 ETS77570.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 ETS77570.1 - 0.073 13.8 0.1 0.19 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 ETS77571.1 - 6.3e-22 77.6 1.1 1.2e-21 76.6 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS77571.1 - 8.7e-07 29.2 0.4 1.8e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain Dynactin PF12455.3 ETS77572.1 - 4.3e-66 222.6 9.9 4.3e-66 222.6 6.8 5.0 4 1 1 5 5 5 2 Dynein associated protein CAP_GLY PF01302.20 ETS77572.1 - 3e-21 74.8 0.8 4.9e-21 74.2 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain SRP19 PF01922.12 ETS77573.1 - 1.5e-29 102.4 0.1 2.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein HTH_Tnp_Tc3_2 PF01498.13 ETS77574.1 - 1e-15 57.5 0.8 1.8e-15 56.7 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 ETS77574.1 - 1.9e-06 27.9 0.3 6.5e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 ETS77574.1 - 0.0038 17.1 1.2 0.017 15.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 ETS77574.1 - 0.01 16.5 1.3 0.025 15.3 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 ETS77574.1 - 0.072 12.5 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 ETS77574.1 - 0.27 10.9 3.6 1 9.1 0.1 2.8 3 0 0 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.1 ETS77575.1 - 3.3e-19 69.0 0.0 6.4e-19 68.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 ETS77575.1 - 0.015 15.3 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Glyco_hydro_61 PF03443.9 ETS77577.1 - 0.0023 17.7 0.1 0.0066 16.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 ETS77577.1 - 0.036 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Chitin binding domain MFS_1 PF07690.11 ETS77578.1 - 3.1e-18 65.6 18.2 4.6e-18 65.0 12.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.16 ETS77579.1 - 7.9e-18 64.6 2.5 1.7e-17 63.5 1.7 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 ETS77580.1 - 3.1e-100 334.2 0.0 3.8e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.13 ETS77581.1 - 1.6e-09 37.0 0.0 4e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77581.1 - 1.3e-06 28.1 11.5 2.3e-06 27.4 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 ETS77582.1 - 0.016 14.9 4.3 0.016 14.9 3.0 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HOOK PF05622.7 ETS77582.1 - 0.042 11.6 0.2 0.059 11.1 0.2 1.2 1 0 0 1 1 1 0 HOOK protein Toxin_21 PF08091.6 ETS77582.1 - 8 6.2 13.5 2.7 7.7 2.2 2.8 2 0 0 2 2 2 0 Spider insecticidal peptide DAO PF01266.19 ETS77584.1 - 2.6e-50 171.3 0.0 3.6e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77584.1 - 2.6e-07 29.8 0.7 9e-07 28.0 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS77584.1 - 5.2e-05 22.5 0.0 0.00053 19.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS77584.1 - 0.0013 18.7 0.1 0.0038 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77584.1 - 0.0026 16.9 0.6 0.3 10.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 ETS77584.1 - 0.003 17.2 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 ETS77584.1 - 0.004 17.1 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS77584.1 - 0.041 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS77584.1 - 0.055 11.9 0.2 0.089 11.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS77584.1 - 0.074 11.9 0.1 0.37 9.6 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 ETS77584.1 - 0.097 11.5 0.0 2.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETS77584.1 - 0.1 11.6 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 ETS77584.1 - 0.13 12.6 0.4 0.36 11.2 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MHYT PF03707.11 ETS77585.1 - 3.1e-05 24.0 27.6 0.001 19.1 1.6 4.5 3 1 0 4 4 4 2 Bacterial signalling protein N terminal repeat Peptidase_U4 PF03419.8 ETS77585.1 - 0.65 9.0 7.4 0.38 9.7 2.7 2.3 2 1 1 3 3 3 0 Sporulation factor SpoIIGA Glyco_hydro_2_C PF02836.12 ETS77586.1 - 8.2e-96 320.4 0.0 1.1e-95 319.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 ETS77586.1 - 1.9e-50 171.4 0.0 2.8e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 ETS77586.1 - 3.1e-47 160.2 0.2 5.1e-47 159.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS77586.1 - 4.2e-12 46.4 0.2 2.4e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Sugar_tr PF00083.19 ETS77587.1 - 1.2e-84 284.5 26.5 1.5e-84 284.2 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77587.1 - 1.2e-38 132.7 41.5 9.9e-34 116.5 16.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS77587.1 - 0.00014 20.2 3.1 0.00014 20.2 2.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 ETS77587.1 - 0.00016 20.2 9.8 0.00016 20.2 6.8 3.4 2 2 2 4 4 4 3 MFS/sugar transport protein Cdd1 PF11731.3 ETS77587.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Pathogenicity locus Bac_rhamnosid PF05592.6 ETS77588.1 - 9.1e-36 123.1 1.5 1.4e-29 102.6 1.3 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 ETS77588.1 - 0.00054 18.7 0.0 0.00084 18.0 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 ETS77588.1 - 0.0037 16.0 4.6 0.0062 15.3 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF608 Amidohydro_1 PF01979.15 ETS77590.1 - 9.6e-13 48.4 2.5 1.5e-12 47.8 1.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS77590.1 - 1.6e-06 27.8 0.0 6.2e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS77590.1 - 7.2e-05 22.9 6.6 0.0014 18.7 4.6 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS77590.1 - 0.00039 19.7 7.6 0.11 11.6 1.8 3.3 1 1 1 2 2 2 2 Amidohydrolase family Metallophos PF00149.23 ETS77591.1 - 0.00089 18.7 1.1 0.0013 18.1 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS77591.1 - 0.0081 16.0 1.8 0.025 14.4 1.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nuc_sug_transp PF04142.10 ETS77593.1 - 3.8e-78 261.9 7.5 5.8e-78 261.3 5.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 ETS77593.1 - 9.4e-07 28.0 14.6 8.6e-06 24.8 9.2 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETS77593.1 - 4.4e-06 26.7 29.6 0.0024 17.8 9.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 ETS77593.1 - 7.3e-06 26.1 17.0 8.9e-05 22.6 1.5 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 ETS77593.1 - 2e-05 24.2 23.3 0.001 18.7 1.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family Senescence PF06911.7 ETS77593.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Senescence-associated protein Sec63 PF02889.11 ETS77594.1 - 1.2e-30 106.8 0.0 1.9e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 ETS77594.1 - 3.6e-25 88.3 0.0 8.1e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS77594.1 - 1e-08 34.8 0.0 3.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 ETS77594.1 - 2.5e-05 24.3 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain RYDR_ITPR PF01365.16 ETS77594.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 RIH domain DNA_pol_lambd_f PF10391.4 ETS77594.1 - 0.12 11.9 0.0 0.48 10.0 0.0 2.0 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda PTS_2-RNA PF01885.11 ETS77595.1 - 1.4e-10 40.8 0.0 3.5e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Lipase_GDSL PF00657.17 ETS77596.1 - 5.9e-15 55.7 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS77596.1 - 9.6e-10 38.8 0.1 1.6e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 ETS77596.1 - 1.4e-07 31.4 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cation_efflux PF01545.16 ETS77597.1 - 7.6e-29 100.6 0.4 1e-28 100.2 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family Velvet PF11754.3 ETS77598.1 - 1.6e-40 138.9 0.1 7.5e-40 136.7 0.0 1.9 2 0 0 2 2 2 1 Velvet factor 4HBT PF03061.17 ETS77599.1 - 5.8e-12 45.5 0.1 8.4e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily KH_1 PF00013.24 ETS77599.1 - 0.0014 18.2 0.1 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF4442 PF14539.1 ETS77599.1 - 0.05 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Bactofilin PF04519.8 ETS77599.1 - 0.2 11.6 3.7 0.32 11.0 0.4 2.3 1 1 1 2 2 2 0 Polymer-forming cytoskeletal Abhydrolase_6 PF12697.2 ETS77600.1 - 1.3e-25 90.6 0.6 1.5e-25 90.4 0.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77600.1 - 4.7e-09 36.1 0.0 7e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 ETS77601.1 - 8.5e-78 261.5 0.0 1.2e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 ETS77601.1 - 3.5e-55 186.9 0.0 9.4e-29 100.2 0.0 2.6 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 ETS77601.1 - 7.7e-17 61.3 0.8 7.2e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 ETS77601.1 - 2.7e-10 40.4 0.3 7e-08 32.6 0.0 3.3 3 0 0 3 3 3 1 HxxPF-repeated domain AMP-binding_C PF13193.1 ETS77601.1 - 4.1e-05 24.4 0.0 0.00025 21.9 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.9 ETS77603.1 - 4.7e-17 62.5 0.0 7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77603.1 - 7e-07 28.4 0.5 5.9e-06 25.3 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 ETS77603.1 - 2.9e-05 23.1 0.1 4e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS77603.1 - 0.00039 19.4 0.2 0.0012 17.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETS77603.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS77603.1 - 0.00085 17.8 0.1 0.0052 15.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS77603.1 - 0.0022 17.9 0.6 0.017 15.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS77603.1 - 0.011 15.5 0.6 3.9 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS77603.1 - 0.019 14.9 0.2 0.71 9.8 0.1 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77603.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 ETS77603.1 - 0.062 12.2 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 ETS77603.1 - 0.075 12.1 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 ETS77603.1 - 0.11 11.0 0.3 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS77604.1 - 4.8e-19 69.0 0.1 6.4e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS77604.1 - 2e-07 30.2 1.2 3.3e-07 29.5 0.2 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77604.1 - 4.4e-06 26.6 2.0 6.8e-06 26.0 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77604.1 - 1.1e-05 24.4 0.1 3.2e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 ETS77604.1 - 7e-05 22.6 0.7 0.089 12.5 0.1 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 ETS77604.1 - 0.0017 17.2 3.5 0.13 11.0 0.8 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS77604.1 - 0.0025 17.9 0.3 0.11 12.4 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77604.1 - 0.0034 16.5 0.0 0.012 14.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 ETS77604.1 - 0.0042 15.6 0.8 0.013 13.9 0.2 1.9 1 1 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS77604.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 ETS77604.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 ETS77604.1 - 0.16 12.3 0.2 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS77604.1 - 0.89 8.5 4.8 0.13 11.2 0.6 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 ETS77605.1 - 3.6e-42 144.3 54.6 8.8e-42 143.0 35.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS77605.1 - 3.3e-18 65.2 13.3 5e-18 64.6 9.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS77605.1 - 1.8e-10 39.9 13.3 1.8e-10 39.9 9.2 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter DUF4335 PF14233.1 ETS77605.1 - 0.053 12.9 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Phage_holin_3 PF05106.7 ETS77605.1 - 0.3 11.1 6.2 0.085 12.8 0.8 2.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Peptidase_M19 PF01244.16 ETS77606.1 - 9e-104 346.8 0.0 1e-103 346.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_2 PF00891.13 ETS77607.1 - 5.3e-20 71.6 0.3 7e-20 71.2 0.2 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS77607.1 - 0.014 16.0 0.0 0.084 13.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.1 ETS77607.1 - 0.043 12.9 0.1 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Avirulence PF03377.8 ETS77607.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Zn_clus PF00172.13 ETS77608.1 - 0.00013 21.7 13.0 0.00024 20.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 ETS77609.1 - 2.6e-34 118.7 0.0 3e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS77609.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Rax2 PF12768.2 ETS77610.1 - 0.046 12.9 0.7 0.71 9.0 0.0 2.6 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Nup35_RRM_2 PF14605.1 ETS77611.1 - 0.032 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_11 PF08241.7 ETS77613.1 - 5.7e-09 36.3 0.0 9.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS77613.1 - 1.8e-06 27.7 0.0 2.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS77613.1 - 3.5e-06 27.3 0.0 6.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77613.1 - 3.2e-05 24.3 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS77613.1 - 4.2e-05 23.5 0.1 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77613.1 - 0.00037 20.0 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS77613.1 - 0.00054 19.1 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS77613.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 ETS77613.1 - 0.047 14.2 0.0 0.087 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 ETS77614.1 - 1.5e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77614.1 - 3.6e-07 29.8 0.0 1.3e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77614.1 - 4.7e-05 23.8 0.0 8.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77614.1 - 0.0025 18.2 0.0 0.0066 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77614.1 - 0.022 15.3 0.0 0.2 12.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77615.1 - 1.3e-13 51.2 0.0 2.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77615.1 - 5e-11 42.9 0.0 9.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS77615.1 - 1.3e-10 41.4 0.0 9.7e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77615.1 - 3.1e-10 39.8 0.0 4.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS77615.1 - 3.1e-10 40.0 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS77615.1 - 6.8e-10 38.4 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS77615.1 - 1.5e-09 37.8 0.1 2.3e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS77615.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETS77615.1 - 0.0065 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS77615.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 ETS77616.1 - 9.1e-40 136.5 0.0 1.2e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-HC2 PF13490.1 ETS77616.1 - 0.14 12.1 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative zinc-finger GST_C PF00043.20 ETS77617.1 - 1.5e-06 28.0 0.1 2.9e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS77617.1 - 1.5e-05 24.8 0.2 3.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS77617.1 - 0.00019 21.3 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS77617.1 - 0.0026 18.1 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS77617.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_32N PF00251.15 ETS77617.1 - 0.077 12.3 0.4 0.097 12.0 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_2 PF00891.13 ETS77618.1 - 1.9e-42 145.1 0.0 3.1e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 ETS77618.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain p450 PF00067.17 ETS77619.1 - 6.8e-05 21.5 0.0 0.00096 17.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.1 ETS77620.1 - 3.2e-18 65.5 3.5 1.1e-17 63.9 2.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Binary_toxB PF03495.9 ETS77623.1 - 0.92 8.0 3.3 1.1 7.8 2.3 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Abhydrolase_3 PF07859.8 ETS77624.1 - 4.1e-49 167.0 0.0 5.7e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS77624.1 - 8.5e-14 51.1 0.0 2.6e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 ETS77624.1 - 0.00022 21.1 0.9 0.00053 19.9 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77624.1 - 0.0005 19.8 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS77624.1 - 0.17 10.4 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) COesterase PF00135.23 ETS77625.1 - 1.9e-105 353.6 0.1 2.5e-105 353.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77625.1 - 0.00012 21.6 0.0 0.0016 18.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS77625.1 - 0.051 12.7 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.14 ETS77626.1 - 1e-49 169.3 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS77626.1 - 2.9e-30 105.4 0.0 4.3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS77626.1 - 0.00075 18.5 0.2 0.0014 17.6 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 ETS77626.1 - 0.0052 15.7 0.1 0.27 10.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS77626.1 - 0.012 14.4 0.3 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS77626.1 - 0.036 13.9 0.1 0.094 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77626.1 - 0.039 12.7 0.1 0.41 9.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Aldo_ket_red PF00248.16 ETS77627.1 - 6.8e-67 225.2 0.0 7.8e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1772 PF08592.6 ETS77628.1 - 1.3e-19 70.3 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Ank_2 PF12796.2 ETS77629.1 - 1.4e-40 137.4 0.0 3.8e-15 55.9 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS77629.1 - 1.2e-32 111.7 0.0 5.1e-11 42.7 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 ETS77629.1 - 1.6e-31 106.5 0.0 3.6e-05 23.3 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETS77629.1 - 7.4e-21 72.1 0.0 0.0072 16.4 0.0 6.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 ETS77629.1 - 1.8e-19 69.3 0.0 3.3e-05 23.9 0.0 5.1 2 1 3 6 6 6 4 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS77629.1 - 7.7e-07 29.2 2.1 3.6e-06 27.0 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ETS77629.1 - 3.3e-06 26.8 1.5 7.4e-06 25.7 0.0 2.2 2 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 ETS77629.1 - 0.00028 21.0 0.0 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS77629.1 - 0.00037 20.7 0.0 0.011 15.9 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS77629.1 - 0.026 14.4 0.0 0.13 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain Bac_luciferase PF00296.15 ETS77631.1 - 2.9e-63 213.8 0.6 3.4e-63 213.6 0.4 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Integrase_1 PF12835.2 ETS77631.1 - 0.048 13.4 0.1 0.67 9.6 0.0 2.3 1 1 0 1 1 1 0 Integrase DUF4253 PF14062.1 ETS77631.1 - 0.049 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Peptidase_M24 PF00557.19 ETS77632.1 - 4.2e-50 170.2 0.0 6e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETS77632.1 - 6e-17 61.2 0.0 1.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HNH_4 PF13395.1 ETS77632.1 - 0.11 12.1 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease ADH_zinc_N_2 PF13602.1 ETS77633.1 - 4.6e-14 53.3 0.0 2.8e-13 50.8 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS77633.1 - 6.6e-13 48.3 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS77633.1 - 0.00026 20.7 0.0 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_6 PF13458.1 ETS77633.1 - 0.059 12.7 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein GDC-P PF02347.11 ETS77633.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dabb PF07876.7 ETS77634.1 - 3.2e-15 56.3 0.0 4.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MFS_1 PF07690.11 ETS77635.1 - 1e-40 139.5 51.1 3.6e-40 137.7 33.0 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily SGL PF08450.7 ETS77636.1 - 1.8e-22 79.8 0.2 6.5e-21 74.8 0.1 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETS77636.1 - 4.1e-07 29.9 0.0 1.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 ETS77636.1 - 5.3e-05 23.1 0.0 0.00016 21.5 0.0 1.9 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 ETS77636.1 - 0.06 13.3 1.5 19 5.4 0.0 3.3 3 0 0 3 3 3 0 NHL repeat PQQ_3 PF13570.1 ETS77636.1 - 0.3 11.4 4.4 15 6.0 0.3 3.5 3 0 0 3 3 3 0 PQQ-like domain TauD PF02668.11 ETS77637.1 - 1.5e-43 149.3 0.1 1.8e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 ETS77638.1 - 2.3e-38 131.8 29.8 2.3e-38 131.8 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77638.1 - 1.1e-09 37.4 3.9 1.1e-09 37.4 2.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS77638.1 - 0.0033 15.5 0.8 0.0054 14.8 0.0 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FTR1 PF03239.9 ETS77638.1 - 0.11 11.4 6.8 0.81 8.5 0.0 2.3 1 1 1 2 2 2 0 Iron permease FTR1 family TauD PF02668.11 ETS77639.1 - 2.7e-37 128.8 0.0 3.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MmgE_PrpD PF03972.9 ETS77640.1 - 1.6e-54 184.7 0.0 2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Acyl_transf_1 PF00698.16 ETS77641.1 - 1.7e-56 191.8 0.0 3.1e-55 187.7 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 ETS77641.1 - 4.8e-29 100.2 0.0 1.3e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 ETS77641.1 - 1.9e-26 91.5 1.1 6e-26 90.0 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 ETS77641.1 - 1e-05 25.3 0.0 0.0024 17.6 0.0 2.8 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase NMO PF03060.10 ETS77641.1 - 0.0011 18.2 0.1 0.28 10.2 0.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase MmgE_PrpD PF03972.9 ETS77642.1 - 3.8e-106 354.9 0.0 4.3e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.16 ETS77643.1 - 3.8e-99 331.7 0.0 4.5e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ketoacyl-synt PF00109.21 ETS77644.1 - 2.4e-22 79.6 0.4 4.6e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS77644.1 - 2.5e-15 56.3 0.1 1.3e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 ETS77644.1 - 7e-15 55.4 0.0 1.6e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS77644.1 - 2.2e-07 30.9 1.4 3.4e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS77644.1 - 1e-05 25.3 0.5 2.7e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Zn_clus PF00172.13 ETS77645.1 - 9.9e-12 44.5 12.2 2.1e-11 43.5 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS77645.1 - 7.4e-09 34.8 0.1 1.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_alpha_N PF12254.3 ETS77647.1 - 0.02 14.6 0.7 0.03 14.1 0.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Sugar_tr PF00083.19 ETS77648.1 - 1.7e-104 349.9 26.8 2e-104 349.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77648.1 - 8.8e-25 87.1 31.8 1.2e-18 66.9 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IlvC PF01450.14 ETS77648.1 - 0.21 11.4 0.5 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ATP-sulfurylase PF01747.12 ETS77650.1 - 6.8e-88 293.5 0.0 9.3e-88 293.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 ETS77650.1 - 3.8e-56 189.1 0.0 5.5e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 ETS77650.1 - 8.2e-55 184.5 0.0 1.3e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Dioxygenase_C PF00775.16 ETS77651.1 - 1e-53 181.3 0.0 1.4e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 ETS77651.1 - 3.6e-16 58.8 0.0 2.9e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 ETS77651.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 ETS77652.1 - 1.5e-25 89.5 0.0 2.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.4 ETS77653.1 - 0.00027 21.0 4.9 0.04 14.0 3.4 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ETS77653.1 - 0.022 14.7 0.1 0.048 13.6 0.1 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Melibiase PF02065.13 ETS77654.1 - 2.5e-43 148.2 0.1 4.3e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 Melibiase MFS_1 PF07690.11 ETS77655.1 - 1.7e-30 105.9 43.6 3.8e-30 104.7 30.2 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS77655.1 - 5e-13 48.1 20.3 7.1e-13 47.6 14.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.21 ETS77656.1 - 1.6e-77 260.4 0.1 3.5e-77 259.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS77656.1 - 4e-50 169.9 0.0 1.4e-49 168.1 0.0 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 ETS77656.1 - 2e-48 165.4 0.1 3.9e-48 164.4 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS77656.1 - 1.1e-39 136.0 0.1 1.1e-38 132.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 ETS77656.1 - 1.6e-37 129.2 0.0 4.5e-37 127.8 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 ETS77656.1 - 8.4e-37 125.6 0.7 4.7e-36 123.2 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_N PF08240.7 ETS77656.1 - 8.9e-05 22.2 0.0 0.0014 18.3 0.1 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 ETS77656.1 - 0.0048 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ThiF PF00899.16 ETS77656.1 - 0.013 15.2 0.5 0.035 13.9 0.4 1.7 1 0 0 1 1 1 0 ThiF family PP-binding PF00550.20 ETS77656.1 - 0.015 15.5 0.0 0.052 13.8 0.0 2.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 ETS77656.1 - 0.059 12.9 1.2 0.17 11.4 0.0 2.4 3 0 0 3 3 3 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 ETS77656.1 - 0.065 13.2 0.1 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Asp PF00026.18 ETS77657.1 - 5.7e-67 226.2 2.2 8.5e-67 225.6 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS77657.1 - 3.2e-07 30.4 0.1 2.2e-05 24.4 0.0 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Sporozoite_P67 PF05642.6 ETS77657.1 - 3.3 5.4 8.2 4.6 4.9 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OPT PF03169.10 ETS77658.1 - 2.9e-182 607.4 48.3 3.4e-182 607.1 33.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MoaE PF02391.12 ETS77659.1 - 1.5e-29 102.1 0.0 1.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.18 ETS77660.1 - 2.8e-09 36.6 1.3 8.9e-09 34.9 0.9 1.9 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 ETS77660.1 - 2.8e-08 33.5 0.2 0.0065 16.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS77660.1 - 1.1e-07 31.3 0.3 0.026 14.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 ETS77660.1 - 2.1e-07 29.8 4.2 3.5e-07 29.1 2.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 ETS77660.1 - 3.7e-05 23.5 3.4 4.6e-05 23.1 0.6 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 ETS77660.1 - 0.01 15.6 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 ETS77660.1 - 0.018 14.2 2.3 0.071 12.3 1.6 2.0 1 0 0 1 1 1 0 RED-like protein N-terminal region ISN1 PF06437.6 ETS77662.1 - 2.3e-177 589.7 0.0 2.7e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Sds3 PF08598.6 ETS77663.1 - 0.76 9.2 15.4 0.022 14.3 6.0 1.8 2 0 0 2 2 2 0 Sds3-like ubiquitin PF00240.18 ETS77665.1 - 0.00011 21.5 0.0 0.00035 19.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETS77665.1 - 0.0016 18.0 1.9 0.0026 17.3 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DUF2235 PF09994.4 ETS77666.1 - 3.6e-28 98.7 0.0 4.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FAD-SLDH PF12318.3 ETS77666.1 - 0.0065 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase IBN_N PF03810.14 ETS77667.1 - 3.3e-14 52.5 0.8 9.6e-11 41.4 0.0 3.1 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cse1 PF08506.5 ETS77667.1 - 8.8e-08 31.1 0.2 3.5e-07 29.1 0.1 1.9 1 1 1 2 2 2 1 Cse1 Xpo1 PF08389.7 ETS77667.1 - 0.00037 20.4 1.4 0.01 15.7 0.0 3.9 5 0 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 ETS77667.1 - 0.0016 18.6 5.1 0.94 9.8 0.0 3.9 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 ETS77667.1 - 0.079 13.0 0.4 0.7 10.1 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.2 ETS77667.1 - 0.16 12.3 3.4 3.7 8.0 0.1 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IMS PF00817.15 ETS77669.1 - 2.8e-43 147.2 0.0 4.5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS77669.1 - 2.7e-13 49.9 0.0 6.8e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 ETS77669.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-met PF12874.2 ETS77669.1 - 0.081 13.1 1.1 0.22 11.7 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-DHHC PF01529.15 ETS77670.1 - 1.7e-23 82.8 9.4 3.9e-23 81.7 5.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Cupin_1 PF00190.17 ETS77671.1 - 5.1e-09 35.6 0.0 8.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ETS77671.1 - 5.4e-09 35.4 0.3 4e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 ETS77671.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 ETS77671.1 - 0.033 13.7 0.5 0.31 10.6 0.3 2.3 1 1 0 1 1 1 0 Cupin Pro_dh PF01619.13 ETS77672.1 - 4.1e-38 131.1 0.0 4.9e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase TauD PF02668.11 ETS77672.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family AAA_assoc PF14363.1 ETS77672.1 - 0.15 12.1 0.5 0.76 9.8 0.2 2.1 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA NUDIX PF00293.23 ETS77673.1 - 3.1e-05 23.6 0.1 5.9e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain HET PF06985.6 ETS77674.1 - 5.5e-20 71.9 0.0 1.3e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.16 ETS77675.1 - 6.9e-101 337.9 39.9 8.5e-101 337.6 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS77675.1 - 9.3e-23 80.4 42.3 1.1e-22 80.1 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease P5CR_dimer PF14748.1 ETS77676.1 - 1e-30 105.9 0.5 2.1e-30 104.8 0.4 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 ETS77676.1 - 1.6e-14 54.0 0.2 1.6e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Senescence PF06911.7 ETS77676.1 - 0.011 15.4 0.2 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Senescence-associated protein NAD_Gly3P_dh_N PF01210.18 ETS77676.1 - 0.023 14.4 0.1 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 ETS77676.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.17 ETS77677.1 - 5.3e-91 305.2 0.0 6.5e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS77677.1 - 0.1 11.2 0.0 3.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF4355 PF14265.1 ETS77677.1 - 0.84 9.5 3.4 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) DAO PF01266.19 ETS77679.1 - 1.7e-46 158.7 0.0 2e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77679.1 - 2.8e-07 30.4 0.0 1e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS77679.1 - 7.9e-05 22.7 0.0 0.00034 20.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77679.1 - 0.00047 20.0 0.2 0.0053 16.6 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77679.1 - 0.00091 18.1 0.2 0.0039 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 ETS77679.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 ETS77679.1 - 0.0029 16.7 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 ETS77679.1 - 0.005 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 ETS77679.1 - 0.0068 16.1 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS77679.1 - 0.0071 16.7 0.1 0.057 13.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS77679.1 - 0.0093 14.8 0.1 2.5 6.8 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 ETS77679.1 - 0.026 13.5 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS77679.1 - 0.044 12.8 0.1 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS77679.1 - 0.049 12.1 0.1 0.24 9.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS77679.1 - 0.11 11.4 0.2 0.52 9.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETS77679.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETS77679.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 ETS77679.1 - 0.15 11.2 0.2 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.11 ETS77679.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.1 ETS77679.1 - 0.15 10.9 0.1 0.51 9.1 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fungal_trans PF04082.13 ETS77680.1 - 3.2e-17 62.2 0.6 6.9e-17 61.1 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77680.1 - 3.5e-07 30.0 12.6 7.3e-07 28.9 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_2 PF03446.10 ETS77681.1 - 8.4e-28 97.2 0.4 1.4e-27 96.5 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS77681.1 - 2.6e-07 30.7 0.2 6.8e-07 29.3 0.2 1.7 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 ETS77681.1 - 0.0011 19.2 0.1 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ETS77681.1 - 0.053 13.6 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_6 PF03737.10 ETS77682.1 - 3e-28 98.6 0.0 4.1e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Dabb PF07876.7 ETS77684.1 - 1.3e-11 44.8 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3246 PF11596.3 ETS77684.1 - 0.029 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PAF-AH_p_II PF03403.8 ETS77685.1 - 5.2e-38 130.3 0.0 5.8e-29 100.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 ETS77685.1 - 8.4e-14 51.5 0.3 2.1e-13 50.2 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS77685.1 - 4.7e-10 39.7 0.2 8.9e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS77685.1 - 1.5e-06 27.2 0.2 7.8e-06 24.9 0.1 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 ETS77685.1 - 0.0022 17.5 0.0 0.0045 16.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS77685.1 - 0.0034 17.2 0.3 0.0088 15.8 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 ETS77685.1 - 0.0038 16.0 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase WD40_alt PF14077.1 ETS77685.1 - 0.064 12.9 0.4 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Abhydrolase_3 PF07859.8 ETS77685.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HTH_Tnp_Tc5 PF03221.11 ETS77686.1 - 1.4e-12 47.2 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 ETS77686.1 - 0.00038 19.9 0.1 0.00066 19.1 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_30 PF13556.1 ETS77686.1 - 0.00065 19.2 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_Tnp_1 PF01527.15 ETS77686.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 ETS77686.1 - 0.01 14.9 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.1 ETS77686.1 - 0.024 14.1 0.3 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.1 ETS77686.1 - 0.033 14.1 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.14 ETS77686.1 - 0.036 13.6 0.3 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.1 ETS77686.1 - 0.039 13.6 0.3 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.1 ETS77686.1 - 0.12 11.8 0.1 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.11 ETS77687.1 - 1.8e-20 72.9 77.8 7.8e-16 57.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS77687.1 - 9.8e-07 27.5 11.3 9.8e-07 27.5 7.9 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein DUF3681 PF12442.3 ETS77687.1 - 0.08 13.1 3.5 0.096 12.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Glyco_hydro_1 PF00232.13 ETS77688.1 - 2.6e-72 243.4 0.7 1.5e-71 241.0 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 zf-H2C2 PF09337.5 ETS77688.1 - 0.033 13.6 1.4 0.14 11.5 0.3 2.2 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger AA_permease_2 PF13520.1 ETS77689.1 - 8.2e-48 162.9 44.8 1e-47 162.6 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS77689.1 - 2.8e-19 68.8 36.0 4e-19 68.3 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease Mac PF12464.3 ETS77690.1 - 1.7e-16 59.9 0.0 2.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 ETS77690.1 - 1.3e-12 46.6 9.3 2.3e-10 39.4 1.7 3.5 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS77690.1 - 4.8e-11 42.0 7.6 2.9e-08 33.1 1.3 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribonuc_L-PSP PF01042.16 ETS77691.1 - 1.5e-11 44.0 0.1 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Beta-lactamase PF00144.19 ETS77692.1 - 2.8e-41 141.6 0.0 5.5e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Abhydrolase_3 PF07859.8 ETS77693.1 - 1.2e-17 64.1 0.0 6.1e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS77693.1 - 1.4e-10 40.8 0.0 4.2e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS77693.1 - 4e-10 39.6 0.0 5.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS77693.1 - 1.4e-07 31.6 0.4 2.3e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETS77693.1 - 0.00039 19.2 0.1 0.0047 15.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 ETS77693.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 ETS77693.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 ETS77693.1 - 0.13 11.7 0.0 8.3 5.7 0.0 2.4 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) DAO PF01266.19 ETS77694.1 - 1e-21 77.2 0.4 1.6e-21 76.6 0.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS77694.1 - 0.00053 20.1 0.1 0.00099 19.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS77694.1 - 0.0008 19.7 1.7 0.0017 18.7 1.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77694.1 - 0.028 14.4 0.3 0.067 13.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS77694.1 - 0.028 14.3 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS77694.1 - 0.032 13.9 0.2 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 ETS77694.1 - 0.035 13.7 0.2 0.069 12.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phenyl_P_gamma PF09662.5 ETS77694.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) FAD_binding_3 PF01494.14 ETS77694.1 - 0.11 11.4 0.3 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 ETS77694.1 - 0.23 10.5 0.6 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Aminotran_4 PF01063.14 ETS77695.1 - 3.2e-39 134.7 0.0 3.8e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans_2 PF11951.3 ETS77696.1 - 2.6e-25 88.8 2.3 4.4e-25 88.0 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 ETS77697.1 - 5.2e-37 127.9 0.1 6.4e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS77697.1 - 1.7e-34 119.1 2.4 2.3e-34 118.7 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS77697.1 - 1e-18 67.6 0.5 1.4e-18 67.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS77697.1 - 2.7e-06 27.0 0.2 8.1e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 ETS77697.1 - 0.0011 18.1 0.1 0.0023 17.0 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 ETS77697.1 - 0.037 12.6 0.1 0.13 10.8 0.1 1.9 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase LsmAD PF06741.8 ETS77697.1 - 0.08 13.0 0.5 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 LsmAD domain 3HCDH_N PF02737.13 ETS77697.1 - 0.091 12.4 0.4 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 ETS77697.1 - 3.1 7.6 5.3 1.4 8.7 1.7 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Amino_oxidase PF01593.19 ETS77698.1 - 1.8e-40 139.4 0.6 4.5e-40 138.0 0.4 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS77698.1 - 9.7e-13 47.7 0.1 1.3e-07 30.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77698.1 - 2e-12 46.9 0.6 5.9e-12 45.4 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77698.1 - 2e-07 30.2 0.0 1.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ETS77698.1 - 4.7e-07 29.2 0.0 2.2e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS77698.1 - 2.7e-06 27.4 0.1 5.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77698.1 - 1.6e-05 24.1 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS77698.1 - 1.6e-05 25.0 0.1 0.00057 20.0 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS77698.1 - 3.2e-05 22.9 0.1 5.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS77698.1 - 4.8e-05 23.6 0.0 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS77698.1 - 5.2e-05 21.8 0.0 0.0001 20.8 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS77698.1 - 0.0015 17.6 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS77698.1 - 0.006 15.5 0.1 0.0089 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 ETS77698.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 ETS77698.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Tri3 PF07428.6 ETS77699.1 - 0.00014 20.6 0.0 0.0004 19.2 0.0 1.6 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.7 ETS77699.1 - 0.0012 17.5 0.0 0.0019 16.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase Glyco_hydro_3 PF00933.16 ETS77700.1 - 1.2e-82 277.3 0.0 1.6e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS77700.1 - 3.6e-41 141.1 0.0 1.4e-23 83.5 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS77700.1 - 1.5e-14 53.6 0.0 2.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CENP-R PF06729.7 ETS77700.1 - 0.068 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R HATPase_c PF02518.21 ETS77702.1 - 1.9e-25 88.7 0.0 3.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS77702.1 - 1.3e-21 76.6 0.8 3.1e-21 75.4 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 ETS77702.1 - 5e-21 75.0 0.0 2e-06 28.1 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.1 ETS77702.1 - 2.7e-14 52.4 0.0 0.0021 17.8 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 ETS77702.1 - 2.1e-12 46.8 0.0 0.00022 20.9 0.0 3.9 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.6 ETS77702.1 - 2.4e-11 43.5 0.0 2.5e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 ETS77702.1 - 2.5e-10 40.3 0.0 0.033 14.2 0.0 5.0 5 0 0 5 5 5 3 PAS fold HisKA PF00512.20 ETS77702.1 - 5.5e-08 32.6 0.3 4.4e-07 29.8 0.2 2.6 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 ETS77702.1 - 0.00074 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain SprT-like PF10263.4 ETS77703.1 - 2.7e-05 23.8 0.0 4.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M50B PF13398.1 ETS77703.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_MA_2 PF13485.1 ETS77703.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily TRP PF06011.7 ETS77704.1 - 6.4e-101 338.0 13.1 1e-100 337.4 9.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 ETS77704.1 - 1.6e-29 102.7 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF1469 PF07332.6 ETS77704.1 - 0.0049 16.5 1.8 0.0049 16.5 1.3 5.0 4 1 1 5 5 5 1 Protein of unknown function (DUF1469) EI24 PF07264.6 ETS77706.1 - 2.6e-09 36.8 10.2 4.9e-09 35.9 7.1 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Cutinase PF01083.17 ETS77707.1 - 1.3e-43 148.8 3.0 1.5e-43 148.6 2.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS77707.1 - 0.00021 20.8 0.3 0.00032 20.1 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 ETS77707.1 - 0.0071 16.1 0.1 0.0087 15.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS77707.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 ETS77707.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) VirJ PF06057.6 ETS77707.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 ETS77707.1 - 0.073 12.4 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 ETS77707.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ABM PF03992.11 ETS77709.1 - 0.00031 20.7 0.6 0.00043 20.2 0.4 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF718 PF05336.8 ETS77709.1 - 0.06 13.1 0.3 0.1 12.4 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF718) AMP-binding PF00501.23 ETS77710.1 - 4.8e-14 51.5 0.0 6.3e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 ETS77711.1 - 3.5e-07 30.4 0.0 0.0028 17.9 0.2 4.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS77711.1 - 6.5e-06 25.8 0.1 11 6.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 ETS77711.1 - 4.3e-05 23.1 0.0 2.1 8.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 ETS77711.1 - 0.0021 18.5 0.2 10 6.7 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77711.1 - 0.0051 17.0 0.2 29 5.0 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) F-box PF00646.28 ETS77711.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.3 ETS77712.1 - 5.4e-05 21.9 0.3 0.012 14.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 ETS77713.1 - 1.1e-09 38.3 0.0 3.2e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS77713.1 - 0.00017 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 ETS77713.1 - 0.055 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_4 PF01565.18 ETS77714.1 - 4.4e-23 81.3 0.9 6.3e-23 80.7 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain zf-H2C2_2 PF13465.1 ETS77715.1 - 0.00039 20.5 5.4 0.014 15.6 0.3 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 ETS77715.1 - 0.019 15.2 1.4 0.019 15.2 0.9 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETS77715.1 - 0.032 14.3 1.3 0.032 14.3 0.9 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS77715.1 - 0.035 14.3 0.5 0.035 14.3 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type CMD PF02627.15 ETS77715.1 - 0.3 10.9 1.7 21 5.0 0.0 2.5 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family zf-C2H2_4 PF13894.1 ETS77715.1 - 1.2 9.6 18.1 0.15 12.4 1.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 ETS77715.1 - 7 6.7 7.3 39 4.3 5.0 2.3 1 1 0 1 1 1 0 TFIIH C1-like domain Glyco_hydro_61 PF03443.9 ETS77716.1 - 5.9e-52 176.6 0.5 6.8e-52 176.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 ETS77716.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Wzt C-terminal domain UQ_con PF00179.21 ETS77717.1 - 8.6e-12 44.6 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 ETS77717.1 - 0.013 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF3049 PF11250.3 ETS77717.1 - 0.045 13.5 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) FAD_binding_3 PF01494.14 ETS77718.1 - 4.1e-06 26.0 0.1 0.078 12.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS77718.1 - 0.00076 19.4 0.3 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS77718.1 - 0.00078 18.6 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 ETS77718.1 - 0.0012 18.6 0.0 0.077 12.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 ETS77718.1 - 0.016 14.1 0.2 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF2673 PF10880.3 ETS77718.1 - 0.025 14.6 0.2 0.07 13.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) Pyr_redox_2 PF07992.9 ETS77718.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS77718.1 - 0.14 12.6 0.0 2.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77718.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_4 PF08386.5 ETS77720.1 - 4.1e-17 61.9 0.0 3.7e-16 58.8 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.2 ETS77720.1 - 1.1e-09 38.5 0.3 9.1e-09 35.5 0.1 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77720.1 - 1.7e-08 34.2 0.0 2.3e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS77720.1 - 0.0016 18.2 0.0 0.0073 16.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Iso_dh PF00180.15 ETS77721.1 - 1.8e-89 300.0 0.0 2.1e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RPAP3_C PF13877.1 ETS77721.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Fungal_trans PF04082.13 ETS77722.1 - 6.9e-26 90.6 0.1 1.2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77723.1 - 6.1e-07 29.2 10.9 8.7e-07 28.7 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P5-ATPase PF12409.3 ETS77724.1 - 1.2 9.0 4.3 1.8 8.4 0.9 2.2 2 0 0 2 2 2 0 P5-type ATPase cation transporter GMC_oxred_N PF00732.14 ETS77726.1 - 4.6e-66 222.9 0.0 6.2e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS77726.1 - 7.6e-40 136.5 0.0 2e-39 135.1 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS77726.1 - 3.4e-07 29.5 0.3 0.00011 21.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS77726.1 - 1e-05 25.7 2.2 0.0028 17.7 0.7 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77726.1 - 0.00011 22.1 0.1 0.00032 20.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77726.1 - 0.00015 20.7 1.0 0.0051 15.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS77726.1 - 0.0023 17.0 0.1 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS77726.1 - 0.0049 16.7 0.5 0.14 12.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS77726.1 - 0.012 14.1 0.3 0.036 12.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS77726.1 - 0.014 14.3 0.1 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS77726.1 - 0.036 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS77726.1 - 0.18 12.2 2.1 2.3 8.6 0.2 3.0 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS77727.1 - 1.1e-15 57.5 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS77727.1 - 1.6e-06 27.2 0.9 0.0006 18.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS77727.1 - 0.00066 19.4 0.7 0.29 10.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS77727.1 - 0.00097 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS77727.1 - 0.0019 16.9 0.6 0.055 12.0 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 ETS77727.1 - 0.0048 17.2 2.0 0.46 10.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS77727.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77727.1 - 0.063 12.1 0.8 0.34 9.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS77727.1 - 0.076 11.8 0.5 0.12 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS77727.1 - 0.16 11.8 2.9 1.2 8.9 2.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 ETS77728.1 - 1.1e-38 133.4 3.0 1.2e-38 133.2 2.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS77728.1 - 2.5e-18 66.2 0.1 3.2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS77728.1 - 3.9e-13 49.5 0.2 3.6e-08 33.2 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 ETS77728.1 - 1.8e-06 27.6 0.1 0.0022 17.6 0.1 2.1 1 1 0 2 2 2 2 Serine hydrolase Thioesterase PF00975.15 ETS77728.1 - 2.8e-06 27.7 0.0 5.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 ETS77728.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 ETS77728.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 ETS77728.1 - 0.0048 16.3 0.0 0.0082 15.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 ETS77728.1 - 0.0063 16.1 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 ETS77728.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.5 ETS77728.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF900 PF05990.7 ETS77728.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.15 ETS77728.1 - 0.082 12.3 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative esterase DUF2974 PF11187.3 ETS77728.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S10 PF00450.17 ETS77728.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase COesterase PF00135.23 ETS77729.1 - 2.6e-101 339.9 0.0 3.1e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS77729.1 - 1.5e-08 34.4 1.4 6.3e-08 32.4 0.0 2.4 2 2 0 2 2 2 1 alpha/beta hydrolase fold QRPTase_C PF01729.14 ETS77730.1 - 4.3e-56 189.0 0.1 5.3e-56 188.7 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 ETS77730.1 - 2.5e-21 75.2 0.0 7e-21 73.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 ETS77730.1 - 0.019 14.5 0.1 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IGPS PF00218.16 ETS77730.1 - 0.039 13.0 0.1 0.38 9.7 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase CAF-1_p150 PF11600.3 ETS77731.1 - 0.11 11.8 1.7 0.14 11.4 1.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Gly_transf_sug PF04488.10 ETS77732.1 - 2.7e-12 46.9 0.0 6.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 ETS77732.1 - 0.015 13.8 0.0 1.7 7.0 0.0 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain AMP-binding PF00501.23 ETS77733.1 - 5.8e-85 285.1 0.0 7.3e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS77733.1 - 7e-17 62.1 0.0 2.6e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pox_A14 PF05767.7 ETS77734.1 - 0.011 15.6 1.7 0.04 13.8 1.2 2.0 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3623 PF12291.3 ETS77734.1 - 0.077 11.9 6.2 0.24 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3623) Metallophos PF00149.23 ETS77735.1 - 7.6e-17 61.3 0.0 2.2e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 ETS77735.1 - 5.9e-13 48.6 0.1 1.7e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 ETS77735.1 - 1.6e-05 23.7 0.1 7.1e-05 21.5 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 ETS77735.1 - 0.0017 18.2 0.0 0.0042 16.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 ETS77735.1 - 0.053 13.6 0.8 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Glyco_hydro_3 PF00933.16 ETS77736.1 - 9.1e-90 300.6 0.0 1.3e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS77736.1 - 1.1e-54 185.3 0.0 1.9e-53 181.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS77736.1 - 9e-19 67.1 0.2 1.7e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2648 PF10855.3 ETS77736.1 - 0.36 10.2 1.5 0.84 9.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) AP_endonuc_2 PF01261.19 ETS77737.1 - 6.5e-35 120.3 0.0 9.6e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UPF0149 PF03695.8 ETS77737.1 - 0.0092 15.8 0.4 0.021 14.6 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0149) Oxysterol_BP PF01237.13 ETS77738.1 - 3.3e-67 226.4 0.0 4.3e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Peptidase_S41 PF03572.13 ETS77740.1 - 7.1e-08 32.0 0.0 2.8e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Mucin PF01456.12 ETS77740.1 - 9.1 6.0 38.2 0.2 11.4 11.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein NRDE PF05742.7 ETS77743.1 - 2.4e-32 112.3 0.0 2.9e-29 102.2 0.0 3.0 1 1 0 1 1 1 1 NRDE protein Tyrosinase PF00264.15 ETS77744.1 - 7.4e-38 130.9 0.9 9.3e-38 130.5 0.6 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M3 PF01432.15 ETS77746.1 - 2.6e-90 303.6 0.0 3.2e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Polysacc_deac_1 PF01522.16 ETS77747.1 - 2.8e-31 107.7 0.0 4.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 ETS77747.1 - 5.6e-12 45.4 22.5 1.1e-11 44.5 15.6 1.4 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 ETS77747.1 - 0.0056 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CN_hydrolase PF00795.17 ETS77749.1 - 6.7e-30 103.8 0.0 9e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_1 PF00667.15 ETS77750.1 - 1e-60 204.9 0.0 4.3e-60 202.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 ETS77750.1 - 2.1e-11 44.3 0.0 1.4e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 ETS77750.1 - 2.6e-08 33.9 0.1 3.2e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 ETS77750.1 - 0.016 15.0 0.6 0.046 13.6 0.4 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 ETS77750.1 - 0.03 14.4 0.0 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain MmgE_PrpD PF03972.9 ETS77751.1 - 2.1e-60 204.1 0.0 2.6e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.13 ETS77752.1 - 3e-07 30.2 12.5 4.8e-07 29.5 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS77752.1 - 0.00028 19.5 0.3 0.00056 18.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 ETS77753.1 - 3.1e-36 125.3 0.0 3.9e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S58 PF03576.9 ETS77754.1 - 3.1e-104 348.6 0.2 3.6e-104 348.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.14 ETS77755.1 - 3.6e-105 351.5 0.0 4.7e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS77755.1 - 6.9e-16 58.3 0.0 3.3e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 ETS77755.1 - 4.5e-05 22.9 0.1 0.00045 19.6 0.1 2.2 1 1 0 1 1 1 1 Periplasmic binding protein DUF348 PF03990.9 ETS77755.1 - 0.0036 16.8 0.1 0.0083 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF348) B12-binding PF02310.14 ETS77755.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 ETS77756.1 - 1.6e-70 237.2 0.0 2.4e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77756.1 - 2.2e-45 154.7 0.0 3.8e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 ETS77756.1 - 2.7e-15 56.5 0.0 8.2e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 ETS77756.1 - 9.1e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS77756.1 - 0.014 15.1 2.4 0.17 11.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.24 ETS77757.1 - 7.6e-94 307.3 31.2 4.2e-14 51.9 0.1 14.4 16 0 0 16 16 16 9 KH domain KH_3 PF13014.1 ETS77757.1 - 8e-69 226.4 23.7 3.8e-11 42.3 0.2 12.6 13 0 0 13 13 13 9 KH domain KH_2 PF07650.12 ETS77757.1 - 1.3e-13 50.2 18.6 0.027 14.0 0.2 9.0 7 1 1 8 8 8 4 KH domain SLS PF14611.1 ETS77757.1 - 1.4e-10 40.9 7.3 0.018 14.4 0.0 6.8 5 1 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 ETS77757.1 - 0.0038 16.8 4.8 0.2 11.3 0.1 5.3 6 0 0 6 6 6 1 KH domain CD99L2 PF12301.3 ETS77758.1 - 0.018 14.7 0.3 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 NUC153 PF08159.7 ETS77759.1 - 7.1e-14 51.0 2.0 1.4e-13 50.1 1.4 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 ETS77759.1 - 1.4e-07 31.0 0.2 0.00028 20.6 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Med13_C PF06333.7 ETS77760.1 - 1e-103 347.1 0.0 1.6e-103 346.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 ETS77760.1 - 6.7e-25 87.6 0.0 1.6e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal p450 PF00067.17 ETS77762.1 - 5.4e-56 190.0 0.0 7.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PNP_UDP_1 PF01048.15 ETS77763.1 - 1.3e-38 132.3 0.1 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DHDPS PF00701.17 ETS77764.1 - 2.5e-40 137.9 0.0 2.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 ETS77765.1 - 1.9e-36 125.5 29.6 1.9e-36 125.5 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM PF03929.11 ETS77765.1 - 2.2 8.8 7.2 1.9 9.0 0.1 3.7 2 0 0 2 2 2 0 PepSY-associated TM helix Fungal_trans PF04082.13 ETS77766.1 - 3.1e-21 75.4 0.0 5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77766.1 - 1.3e-08 34.6 9.3 2.1e-08 33.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 ETS77767.1 - 6.8e-08 31.8 12.7 1.2e-06 27.7 8.8 2.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DOPA_dioxygen PF08883.6 ETS77768.1 - 1.7e-29 101.9 0.0 4.9e-29 100.4 0.0 1.6 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family HLH PF00010.21 ETS77769.1 - 1.1e-16 60.3 0.0 2.9e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M24 PF00557.19 ETS77770.1 - 2.1e-48 164.6 0.0 3e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 ETS77770.1 - 1.7e-32 111.6 0.0 3.2e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 ETS77771.1 - 3.4e-43 146.3 0.0 7.9e-43 145.2 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 ETS77771.1 - 8.8e-24 82.9 0.6 1.9e-23 81.8 0.4 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 ETS77771.1 - 0.00027 20.9 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 ETS77771.1 - 0.008 16.0 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain Tyrosinase PF00264.15 ETS77773.1 - 9.6e-47 159.9 0.0 1.2e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase 4HBT PF03061.17 ETS77774.1 - 0.00095 19.2 0.8 0.013 15.5 0.1 2.3 2 0 0 2 2 2 1 Thioesterase superfamily APG12 PF04110.8 ETS77775.1 - 6.6e-26 90.3 0.0 8.7e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 ETS77775.1 - 0.00017 21.5 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 ETS77776.1 - 3.9e-102 340.8 0.6 4.6e-102 340.5 0.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 ETS77776.1 - 9.6e-11 41.3 1.4 2e-10 40.2 1.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NmrA PF05368.8 ETS77777.1 - 4.6e-16 58.7 0.2 7.5e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS77777.1 - 9.8e-15 55.0 0.2 1.7e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS77777.1 - 2e-09 36.8 0.1 2.7e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETS77777.1 - 3.7e-06 26.5 0.0 3.4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS77777.1 - 0.00013 21.0 0.1 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 ETS77777.1 - 0.00044 19.0 0.1 0.00072 18.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETS77777.1 - 0.00062 19.6 0.6 0.0013 18.6 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.11 ETS77777.1 - 0.001 18.4 0.1 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 ETS77777.1 - 0.002 18.5 0.5 0.0045 17.4 0.4 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 ETS77777.1 - 0.0048 17.2 0.1 0.0081 16.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS77777.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 ETS77777.1 - 0.06 13.4 0.2 0.09 12.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 ETS77777.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 KR domain dTMP_synthase PF02593.9 ETS77777.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase Pkinase PF00069.20 ETS77779.1 - 3.2e-26 92.0 0.0 1.8e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77779.1 - 6e-15 55.0 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS77779.1 - 0.0038 16.9 3.9 0.043 13.5 0.3 3.2 3 1 1 4 4 4 1 Phosphotransferase enzyme family Ank_2 PF12796.2 ETS77780.1 - 3.3e-33 113.8 0.0 5.9e-08 32.9 0.1 8.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77780.1 - 1.4e-25 87.7 11.4 1.5e-05 24.5 0.1 10.7 9 1 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 ETS77780.1 - 8.7e-23 78.1 7.3 0.0013 18.8 0.0 11.0 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 ETS77780.1 - 1.1e-17 63.6 8.9 0.00083 19.5 0.0 9.3 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS77780.1 - 1.4e-15 57.2 4.4 0.04 14.4 0.0 8.6 8 1 1 9 9 9 4 Ankyrin repeats (many copies) PQ-loop PF04193.9 ETS77782.1 - 1.6e-39 133.2 13.3 7.8e-21 73.3 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat PDGLE PF13190.1 ETS77782.1 - 0.023 14.3 1.1 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 PDGLE domain S1-P1_nuclease PF02265.11 ETS77783.1 - 2e-69 234.0 0.3 2.3e-69 233.8 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease W_rich_C PF07483.6 ETS77783.1 - 0.013 15.1 0.1 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain BAF1_ABF1 PF04684.8 ETS77784.1 - 0.00056 18.8 9.6 0.00056 18.8 6.7 2.4 2 1 1 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 ETS77784.1 - 0.28 10.4 23.1 0.19 11.0 9.3 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein SPX PF03105.14 ETS77784.1 - 0.4 10.4 19.1 0.35 10.5 6.8 2.1 2 0 0 2 2 2 0 SPX domain TT_ORF1 PF02956.9 ETS77784.1 - 0.5 8.7 13.4 0.18 10.2 5.5 2.0 2 0 0 2 2 2 0 TT viral orf 1 DUF966 PF06136.8 ETS77784.1 - 1.1 8.6 13.4 0.73 9.1 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) RP-C_C PF11800.3 ETS77784.1 - 1.2 8.7 17.2 0.6 9.7 5.1 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Ctr PF04145.10 ETS77784.1 - 1.4 8.9 10.2 10 6.1 3.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family AUX_IAA PF02309.11 ETS77784.1 - 1.9 8.1 11.5 0.24 11.1 2.3 2.2 2 0 0 2 2 2 0 AUX/IAA family Paramyxo_ncap PF00973.14 ETS77784.1 - 2.1 6.9 8.6 0.35 9.4 1.8 2.0 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Gti1_Pac2 PF09729.4 ETS77784.1 - 2.3 8.0 12.2 3.4 7.5 4.2 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family WES_acyltransf PF03007.11 ETS77784.1 - 2.8 7.4 4.5 5.6 6.4 3.1 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Hid1 PF12722.2 ETS77784.1 - 4.5 4.8 21.0 0.47 8.0 7.2 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Afi1 PF07792.7 ETS77784.1 - 5.5 6.9 23.8 7.6 6.5 8.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4175 PF13779.1 ETS77784.1 - 5.7 4.4 31.8 0.083 10.5 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2201_N PF13203.1 ETS77784.1 - 6.2 5.8 18.5 4.6 6.3 1.8 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain TFIIA PF03153.8 ETS77784.1 - 7.1 6.4 31.4 1.5 8.6 11.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 ETS77784.1 - 7.4 6.3 12.7 2.1 8.1 3.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Utp14 PF04615.8 ETS77784.1 - 7.8 4.5 20.1 1.1 7.4 7.9 2.0 2 0 0 2 2 2 0 Utp14 protein Raftlin PF15250.1 ETS77784.1 - 9.7 4.5 14.8 10 4.5 6.3 2.1 2 0 0 2 2 2 0 Raftlin HMG_box_2 PF09011.5 ETS77785.1 - 0.043 14.1 0.1 0.093 13.1 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain IBR PF01485.16 ETS77786.1 - 1.9e-11 43.6 47.3 1.2e-06 28.2 10.1 3.6 3 1 0 3 3 3 2 IBR domain adh_short PF00106.20 ETS77787.1 - 5e-17 62.3 0.0 8.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS77787.1 - 2e-08 34.1 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS77787.1 - 0.0036 16.7 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S58 PF03576.9 ETS77788.1 - 4.4e-78 262.7 5.1 2.7e-70 237.1 0.9 2.0 2 0 0 2 2 2 2 Peptidase family S58 DAGK_cat PF00781.19 ETS77788.1 - 0.055 12.9 2.3 0.83 9.0 0.5 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain T2SM_b PF10741.4 ETS77789.1 - 0.038 13.5 0.2 5.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b CorA PF01544.13 ETS77789.1 - 0.74 8.7 8.4 0.093 11.7 1.8 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Glyco_hydro_2_N PF02837.13 ETS77790.1 - 1.3e-35 122.4 0.1 1e-34 119.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 ETS77790.1 - 4.9e-28 97.8 0.0 9.8e-28 96.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETS77790.1 - 3.2e-14 53.3 0.1 8.6e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 ETS77790.1 - 0.00018 21.7 0.2 0.005 17.0 0.0 2.8 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DUF3176 PF11374.3 ETS77791.1 - 2.8e-37 126.9 3.0 8.4e-37 125.4 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) DUF1616 PF07760.6 ETS77791.1 - 0.25 10.4 2.5 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) NfeD PF01957.13 ETS77791.1 - 0.31 11.1 9.4 0.68 10.0 0.3 3.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Tyr-DNA_phospho PF06087.7 ETS77792.1 - 3.3e-42 144.6 0.0 1.2e-41 142.8 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 ETS77792.1 - 0.00014 21.6 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain HiaBD2 PF15403.1 ETS77792.1 - 0.19 11.9 3.9 0.089 12.9 0.8 1.9 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) GPI2 PF06432.6 ETS77793.1 - 3.5e-118 394.0 1.2 4.3e-118 393.7 0.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2207 PF09972.4 ETS77793.1 - 0.15 10.6 0.1 1.5 7.3 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Annexin PF00191.15 ETS77795.1 - 5.1e-16 58.3 0.3 0.00035 20.4 0.0 4.5 4 0 0 4 4 4 4 Annexin FAD_binding_3 PF01494.14 ETS77796.1 - 1e-16 60.9 0.3 4e-09 35.9 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS77796.1 - 0.0024 17.8 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS77796.1 - 0.0081 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS77796.1 - 0.078 11.8 0.2 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 ETS77796.1 - 0.085 11.7 0.6 0.19 10.5 0.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS77797.1 - 1.4e-16 60.6 0.4 1.6e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS77797.1 - 2.5e-15 56.2 0.0 1.8e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS77797.1 - 5.5e-15 55.1 0.1 1.4e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77797.1 - 2.9e-07 29.6 1.9 1.6e-05 23.9 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS77797.1 - 1.4e-06 27.0 0.2 0.00043 18.8 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 ETS77797.1 - 2.9e-05 24.2 0.0 0.0021 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77797.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS77797.1 - 4.7e-05 22.6 1.1 0.0014 17.7 1.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS77797.1 - 0.00027 20.1 0.2 0.00045 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 ETS77797.1 - 0.0015 17.6 0.3 0.0041 16.2 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 ETS77797.1 - 0.0072 16.1 0.9 0.16 11.7 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS77797.1 - 0.014 15.7 1.6 0.15 12.4 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS77797.1 - 0.021 13.7 3.1 0.039 12.7 1.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 ETS77797.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 ETS77797.1 - 0.03 13.7 0.3 0.054 12.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 ETS77797.1 - 0.03 12.9 0.5 2.4 6.7 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase IlvN PF07991.7 ETS77797.1 - 0.092 12.1 0.1 0.38 10.1 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 ETS77797.1 - 0.11 11.3 0.9 0.46 9.3 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS77797.1 - 0.12 11.9 0.8 0.21 11.2 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YpzG PF14139.1 ETS77797.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 YpzG-like protein SQS_PSY PF00494.14 ETS77798.1 - 8.2e-68 228.5 0.7 1e-67 228.2 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF59 PF01883.14 ETS77798.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF59 FAD_binding_7 PF03441.9 ETS77799.1 - 1.2e-58 198.5 0.3 1.7e-58 198.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS77799.1 - 1.8e-18 66.8 0.2 3.5e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Ustilago_mating PF05722.7 ETS77799.1 - 0.076 12.3 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein 4HBT PF03061.17 ETS77800.1 - 0.00097 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-C2H2_4 PF13894.1 ETS77801.1 - 7.5e-06 25.9 19.5 0.0041 17.3 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS77801.1 - 0.00088 19.4 24.4 0.57 10.6 3.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type Syndecan PF01034.15 ETS77801.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_YMGG PF13441.1 ETS77801.1 - 0.22 11.0 2.1 0.36 10.3 1.5 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper MmgE_PrpD PF03972.9 ETS77803.1 - 3.8e-149 496.6 0.0 4.4e-149 496.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TPT PF03151.11 ETS77804.1 - 7.7e-27 93.8 11.8 7.7e-27 93.8 8.2 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETS77804.1 - 3.4e-06 26.2 21.3 7.9e-05 21.7 14.8 2.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETS77804.1 - 0.015 15.3 7.4 0.015 15.3 5.2 2.9 3 1 0 3 3 3 0 EamA-like transporter family Med31 PF05669.7 ETS77805.1 - 1.9e-37 127.1 0.7 2.1e-37 127.0 0.5 1.0 1 0 0 1 1 1 1 SOH1 RAI16-like PF10257.4 ETS77805.1 - 0.033 13.1 0.1 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein Type_III_YscX PF09474.5 ETS77805.1 - 0.099 12.6 0.1 0.14 12.1 0.0 1.3 1 1 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) TFIIS_C PF01096.13 ETS77806.1 - 1.4e-13 50.2 3.2 6.5e-13 48.0 0.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 ETS77806.1 - 1.1e-05 24.9 1.1 3e-05 23.6 0.7 1.8 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.1 ETS77806.1 - 0.0017 17.9 1.8 0.0029 17.2 1.2 1.4 1 0 0 1 1 1 1 Nudix N-terminal Elf1 PF05129.8 ETS77806.1 - 0.0047 16.5 0.3 0.011 15.4 0.1 1.6 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 ETS77806.1 - 0.0055 16.4 3.1 0.014 15.1 0.6 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF2387 PF09526.5 ETS77806.1 - 0.0071 16.2 0.6 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 Probable metal-binding protein (DUF2387) DZR PF12773.2 ETS77806.1 - 0.053 13.3 1.5 0.063 13.1 0.2 1.7 2 0 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 ETS77806.1 - 0.087 13.0 0.2 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 ETS77806.1 - 0.13 12.5 1.2 0.5 10.6 0.8 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-TFIIB PF13453.1 ETS77806.1 - 1.2 8.4 4.2 1.5 8.0 0.8 2.5 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 ETS77806.1 - 1.3 8.3 5.3 0.21 10.8 0.7 2.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 ETS77806.1 - 7.1 7.1 7.4 61 4.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Ank_2 PF12796.2 ETS77807.1 - 5.8e-12 45.7 0.1 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77807.1 - 1.7e-09 37.0 0.0 0.028 14.2 0.1 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETS77807.1 - 1.1e-08 34.4 0.1 0.033 14.4 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS77807.1 - 6.8e-08 32.8 0.2 1.3e-05 25.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77807.1 - 3.1e-05 24.0 0.4 1.1 9.5 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) CFEM PF05730.6 ETS77808.1 - 2.2e-10 40.2 14.4 3.3e-10 39.6 10.0 1.3 1 0 0 1 1 1 1 CFEM domain DsbB PF02600.11 ETS77808.1 - 0.085 12.6 4.3 0.13 12.0 3.0 1.3 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Thaumatin PF00314.12 ETS77809.1 - 1.5e-72 243.5 5.2 1.8e-72 243.2 3.6 1.1 1 0 0 1 1 1 1 Thaumatin family Ank_2 PF12796.2 ETS77811.1 - 6.7e-23 80.8 0.2 3.5e-12 46.5 0.1 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77811.1 - 3.7e-21 73.7 1.1 2.2e-08 33.4 0.0 5.5 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETS77811.1 - 1.2e-16 60.6 1.1 8.3e-07 29.3 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77811.1 - 2.3e-14 53.0 0.7 0.00012 22.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77811.1 - 7.5e-12 44.2 0.2 3.8e-05 23.5 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat KicB PF03882.9 ETS77811.1 - 0.035 12.7 0.2 0.054 12.1 0.2 1.2 1 0 0 1 1 1 0 KicB killing factor HSP70 PF00012.15 ETS77812.1 - 4.2e-11 41.4 0.3 1.7e-09 36.1 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 ETS77812.1 - 0.016 14.8 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 ETS77812.1 - 0.023 13.2 0.1 0.15 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Methyltransf_24 PF13578.1 ETS77813.1 - 4.2e-06 27.5 0.0 1e-05 26.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS77813.1 - 3.8e-05 24.2 0.0 6.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF791 PF05631.9 ETS77814.1 - 7.4e-66 222.2 10.4 1.1e-65 221.6 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETS77814.1 - 1.1e-18 67.0 25.1 1.1e-18 67.0 17.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 ETS77814.1 - 6.8 5.4 12.4 0.43 9.3 3.8 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Hexokinase_2 PF03727.11 ETS77815.1 - 1.3e-65 221.0 0.0 2.4e-65 220.1 0.0 1.4 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 ETS77815.1 - 4.6e-65 218.8 0.0 7.1e-65 218.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Acetyltransf_1 PF00583.19 ETS77816.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS77816.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BamHI PF02923.10 ETS77816.1 - 0.057 13.3 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BamHI Sgf11 PF08209.6 ETS77817.1 - 2.5 7.4 7.7 0.21 10.9 2.2 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 ETS77818.1 - 6.6e-50 169.3 0.0 7.8e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 ETS77819.1 - 1.9e-50 171.9 6.1 1e-49 169.6 4.2 2.0 1 1 0 1 1 1 1 Signal peptide peptidase UPF0233 PF06781.7 ETS77819.1 - 0.28 10.8 4.1 2.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) ACPS PF01648.15 ETS77820.1 - 1.3e-07 31.3 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NUDIX PF00293.23 ETS77821.1 - 2.9e-11 43.1 0.1 2e-10 40.4 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.13 ETS77822.1 - 1.9e-17 63.2 0.0 2.2e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS77822.1 - 2.7e-05 23.9 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family His_Phos_1 PF00300.17 ETS77824.1 - 6.7e-08 32.7 0.2 1.5e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ATP12 PF07542.6 ETS77825.1 - 4.5e-30 104.1 0.0 6.5e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein Med17 PF10156.4 ETS77825.1 - 0.1 10.8 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex HET PF06985.6 ETS77827.1 - 7.9e-23 81.1 0.0 1.6e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS77829.1 - 1.8e-59 201.4 0.0 3.6e-59 200.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 ETS77830.1 - 2.7e-99 325.6 23.3 1.9e-14 53.7 0.0 7.4 3 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77830.1 - 4.9e-70 228.0 7.8 3.6e-07 29.6 0.1 13.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 ETS77830.1 - 4.4e-62 205.4 7.9 2.3e-08 34.3 0.1 11.1 7 2 5 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77830.1 - 3.7e-57 189.0 11.1 1.3e-07 31.6 0.0 11.5 4 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS77830.1 - 1.7e-53 173.2 3.5 0.00074 19.5 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat CorA PF01544.13 ETS77830.1 - 2.1e-09 36.8 0.4 4.7e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MerR PF00376.18 ETS77830.1 - 0.05 13.1 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 MerR family regulatory protein Mem_trans PF03547.13 ETS77831.1 - 1.2e-51 175.1 0.7 8.6e-51 172.4 0.5 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF914 PF06027.7 ETS77834.1 - 5.1e-98 328.0 20.3 6.7e-98 327.6 14.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 ETS77834.1 - 0.00015 21.7 13.0 0.00015 21.7 9.0 2.8 2 1 1 3 3 3 2 EamA-like transporter family Metallophos PF00149.23 ETS77835.1 - 9.8e-07 28.3 8.3 8.7e-06 25.2 5.8 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS77835.1 - 3.3e-05 23.7 0.0 9.9e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RTA1 PF04479.8 ETS77836.1 - 5.4e-41 140.5 7.5 7.4e-41 140.0 5.2 1.2 1 0 0 1 1 1 1 RTA1 like protein SHR3_chaperone PF08229.6 ETS77836.1 - 0.022 13.7 1.8 0.042 12.7 1.2 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 FAD_binding_4 PF01565.18 ETS77837.1 - 1.8e-21 76.0 3.2 4e-21 74.9 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS77837.1 - 2.9e-12 46.2 1.1 5.5e-12 45.3 0.7 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS77837.1 - 0.064 12.3 0.0 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.6 ETS77838.1 - 1.6e-26 93.1 0.0 2.5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DHQS PF01959.11 ETS77839.1 - 0.04 12.6 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) MFS_1 PF07690.11 ETS77840.1 - 6.5e-22 77.7 26.5 6.5e-22 77.7 18.3 3.0 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS77840.1 - 0.043 11.9 8.4 0.0051 15.0 2.7 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4448 PF14610.1 ETS77840.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) UPF0139 PF03669.8 ETS77840.1 - 0.4 10.2 2.2 11 5.5 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) IBR PF01485.16 ETS77841.1 - 1.3e-13 50.6 32.0 2.4e-07 30.5 3.3 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 ETS77841.1 - 0.00011 21.9 4.9 0.00011 21.9 3.4 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 ETS77841.1 - 0.00075 19.1 5.6 0.00075 19.1 3.9 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS77841.1 - 0.0011 18.5 6.5 0.0011 18.5 4.5 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS77841.1 - 0.0062 16.5 6.5 0.0062 16.5 4.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4446 PF14584.1 ETS77841.1 - 1.9 8.3 10.2 4 7.2 1.7 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) RhoGAP PF00620.22 ETS77842.1 - 5.4e-49 165.7 0.1 1.9e-48 163.9 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 ETS77842.1 - 5.9e-15 55.2 0.2 5.9e-15 55.2 0.1 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain IFT43 PF15305.1 ETS77842.1 - 0.07 13.1 1.2 0.16 12.0 0.9 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 UPF0139 PF03669.8 ETS77843.1 - 0.00035 20.0 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 ETS77844.1 - 7.9e-27 93.0 0.3 2.1e-26 91.6 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 ETS77844.1 - 0.00049 18.7 0.2 0.024 13.1 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic Mediator 12 subunit domain HTH_Mga PF08280.6 ETS77844.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain FeoC PF09012.5 ETS77844.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator PI-PLC-X PF00388.14 ETS77845.1 - 9.6e-60 200.2 0.0 1.8e-59 199.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS77845.1 - 6.9e-38 129.2 0.0 1.2e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Fungal_trans PF04082.13 ETS77846.1 - 6.9e-08 31.6 0.7 1.2e-07 30.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS77846.1 - 5.8e-07 29.3 12.2 9.1e-07 28.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.14 ETS77848.1 - 5.9e-23 80.5 87.5 2.7e-10 40.0 6.2 7.1 5 1 1 6 6 6 4 WSC domain RabGAP-TBC PF00566.13 ETS77849.1 - 5.4e-46 156.7 0.0 8.7e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 ETS77849.1 - 2.9e-05 23.5 0.7 0.0088 15.8 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 ETS77849.1 - 0.00011 22.2 0.1 0.0014 18.7 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS77849.1 - 0.0024 17.0 1.0 0.079 12.3 0.2 3.2 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 ETS77849.1 - 0.013 14.7 0.9 0.058 12.7 0.6 2.1 1 0 0 1 1 1 0 EF hand Pkinase PF00069.20 ETS77850.1 - 2.7e-66 223.3 0.0 3.2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77850.1 - 2.8e-34 118.3 0.0 3.8e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS77850.1 - 7.7e-06 25.0 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS77850.1 - 0.00012 21.9 0.2 0.019 14.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS77850.1 - 0.021 13.6 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 ETS77851.1 - 6.9e-09 35.7 2.8 1.7e-08 34.4 0.3 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS77851.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETS77851.1 - 0.58 9.4 0.0 0.58 9.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Exo_endo_phos PF03372.18 ETS77852.1 - 7.4e-16 58.8 0.5 9.3e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 ETS77853.1 - 1.6e-38 132.3 0.0 1.9e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS77853.1 - 8.7e-14 51.2 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS77853.1 - 1.6e-05 24.8 0.1 0.0015 18.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETS77853.1 - 0.054 12.2 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF829 PF05705.9 ETS77854.1 - 3.1e-51 174.4 0.0 3.5e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 ETS77854.1 - 0.0012 18.7 0.1 0.0018 18.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS77854.1 - 0.028 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family ADH_zinc_N PF00107.21 ETS77858.1 - 2.3e-12 46.6 0.1 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS77858.1 - 7.2e-12 45.0 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 ETS77858.1 - 0.0003 20.4 0.3 0.013 15.1 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Dioxygenase_C PF00775.16 ETS77859.1 - 5.5e-10 38.7 0.0 8.5e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase SRP-alpha_N PF04086.8 ETS77861.1 - 9.9e-75 251.4 0.0 1.3e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 ETS77861.1 - 4.5e-53 179.6 0.1 7.6e-53 178.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 ETS77861.1 - 3.3e-08 32.6 0.2 6.1e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 ETS77861.1 - 3.2e-06 27.1 0.1 9.9e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 ETS77861.1 - 8.2e-05 22.0 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 ETS77861.1 - 0.0011 18.7 0.4 0.0038 16.9 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 ETS77861.1 - 0.0081 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 ETS77861.1 - 0.017 14.9 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS77861.1 - 0.026 14.0 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETS77861.1 - 0.027 13.9 0.3 0.067 12.6 0.2 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 ETS77861.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 ETS77861.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 ETS77861.1 - 0.094 12.8 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 ETS77861.1 - 0.098 12.3 0.2 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase YIF1 PF03878.10 ETS77862.1 - 1.6e-72 243.5 1.4 1.9e-72 243.2 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 ETS77862.1 - 0.0052 16.3 8.1 0.0052 16.3 5.6 1.6 2 0 0 2 2 2 1 Yip1 domain Mpv17_PMP22 PF04117.7 ETS77863.1 - 3.3e-18 65.0 10.7 1.1e-16 60.2 0.6 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family HSP70 PF00012.15 ETS77864.1 - 3.7e-266 883.8 15.2 4.2e-266 883.6 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS77864.1 - 2.6e-19 69.0 2.0 7.3e-18 64.2 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Radial_spoke_3 PF06098.6 ETS77864.1 - 0.006 15.6 1.8 0.013 14.5 1.3 1.5 1 0 0 1 1 1 1 Radial spoke protein 3 DDR PF08841.5 ETS77864.1 - 0.025 13.4 2.2 0.14 10.9 0.2 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 ETS77864.1 - 0.053 12.6 4.9 0.14 11.2 0.2 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2758 PF10957.3 ETS77864.1 - 0.16 11.8 1.4 4.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) FtsA PF14450.1 ETS77864.1 - 3.5 7.4 9.4 10 5.9 1.7 3.9 2 2 0 2 2 2 0 Cell division protein FtsA Sugar_tr PF00083.19 ETS77865.1 - 5.7e-31 107.5 32.7 3e-18 65.6 9.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS77865.1 - 2.6e-26 92.1 41.1 6.8e-14 51.3 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CD52 PF15116.1 ETS77865.1 - 2.5 7.9 6.3 47 3.8 0.0 3.5 3 0 0 3 3 3 0 CAMPATH-1 antigen PEX11 PF05648.9 ETS77866.1 - 8.3e-74 247.6 0.2 9.3e-74 247.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.3 ETS77866.1 - 0.31 11.0 2.5 0.48 10.3 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2805) Ribosomal_S7 PF00177.16 ETS77867.1 - 1.1e-22 80.1 0.0 3e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e p450 PF00067.17 ETS77868.1 - 4e-32 111.3 0.0 2.4e-30 105.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Thiolase_N PF00108.18 ETS77869.1 - 8e-76 254.4 4.3 1.2e-75 253.8 3.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS77869.1 - 4e-45 152.2 0.3 7.8e-45 151.2 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 ETS77869.1 - 0.0079 16.1 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal OCD_Mu_crystall PF02423.10 ETS77870.1 - 1.9e-13 49.8 0.2 6.6e-08 31.6 0.0 3.0 3 2 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Macoilin PF09726.4 ETS77870.1 - 3.9 5.6 5.7 5.7 5.0 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Pro_CA PF00484.14 ETS77871.1 - 1.5e-43 148.4 0.1 1.8e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.21 ETS77872.1 - 2.8e-21 74.8 0.5 4.6e-21 74.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.15 ETS77873.1 - 4.9e-18 65.2 0.0 8.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 ETS77873.1 - 0.00035 20.8 0.0 0.001 19.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 ETS77873.1 - 0.00093 18.5 0.4 0.00093 18.5 0.3 3.6 4 0 0 4 4 4 1 RecR protein DUF4428 PF14471.1 ETS77873.1 - 0.016 14.9 0.6 0.016 14.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) tRNA_Me_trans PF03054.11 ETS77873.1 - 0.027 13.0 0.0 0.046 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase MOZ_SAS PF01853.13 ETS77875.1 - 2.5e-80 268.1 0.1 3.5e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 ETS77875.1 - 5.3e-05 22.8 7.4 5.3e-05 22.8 5.1 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 ETS77875.1 - 0.022 14.0 2.8 0.056 12.7 1.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-MIZ PF02891.15 ETS77875.1 - 0.17 11.3 2.4 0.5 9.9 1.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ENTH PF01417.15 ETS77876.1 - 5.3e-50 168.4 0.1 7.5e-50 167.9 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 ETS77876.1 - 0.00062 18.5 0.0 0.00097 17.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 ETS77876.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF1510 PF07423.6 ETS77876.1 - 0.061 12.6 6.5 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) UIM PF02809.15 ETS77876.1 - 0.062 12.8 0.3 0.062 12.8 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 ETS77876.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Usp PF00582.21 ETS77877.1 - 2.1e-20 73.3 4.7 6.1e-12 45.9 0.1 2.8 3 0 0 3 3 3 2 Universal stress protein family RRM_1 PF00076.17 ETS77879.1 - 3e-82 270.2 4.2 4.2e-22 77.5 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS77879.1 - 1.9e-54 181.5 0.3 1.3e-14 53.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS77879.1 - 3.4e-40 135.6 0.0 1.3e-09 37.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 ETS77879.1 - 2.4e-28 97.6 3.3 4.6e-28 96.6 0.8 2.6 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 ETS77879.1 - 0.00022 20.9 0.4 6.3 6.6 0.0 4.9 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 ETS77879.1 - 0.0011 18.6 1.2 0.67 9.7 0.0 3.8 4 0 0 4 4 4 1 Limkain b1 TC1 PF15063.1 ETS77879.1 - 0.011 15.2 0.1 2 8.0 0.0 2.8 2 0 0 2 2 2 0 Thyroid cancer protein 1 CbiG_mid PF11761.3 ETS77879.1 - 0.012 15.8 0.4 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 ETS77879.1 - 0.041 13.3 1.7 7.1 6.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 ETS77880.1 - 4.8e-82 275.6 0.0 6.7e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GspL_C PF12693.2 ETS77880.1 - 0.032 13.9 5.3 2.8 7.6 0.0 2.7 2 0 0 2 2 2 0 GspL periplasmic domain IQ PF00612.22 ETS77880.1 - 0.1 12.2 4.4 0.25 11.0 3.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif RCC1 PF00415.13 ETS77881.1 - 8e-24 83.6 0.0 5.6e-06 26.4 0.0 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 ETS77881.1 - 7.9e-15 54.8 0.0 8.1e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 ETS77881.1 - 2e-09 37.6 0.4 1.5e-08 34.8 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 ETS77881.1 - 3.8e-09 35.9 11.4 6.3e-09 35.2 0.8 4.4 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 ETS77881.1 - 2.9e-06 26.9 0.3 0.0048 17.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETS77881.1 - 1e-05 25.7 0.1 3.4e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77881.1 - 0.0039 16.9 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Mito_carr PF00153.22 ETS77882.1 - 4.4e-69 228.2 2.1 4.3e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 ETS77882.1 - 0.12 12.4 1.4 0.77 9.8 0.0 2.9 3 1 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_43 PF04616.9 ETS77883.1 - 3e-65 220.1 1.5 4e-65 219.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fib_succ_major PF09603.5 ETS77883.1 - 0.15 12.5 1.0 19 5.6 0.1 2.5 2 0 0 2 2 2 0 Fibrobacter succinogenes major domain (Fib_succ_major) Amidoligase_2 PF12224.3 ETS77884.1 - 3.7e-22 79.1 0.0 3.6e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 Putative amidoligase enzyme GAGE PF05831.6 ETS77885.1 - 0.093 12.8 1.6 0.2 11.7 0.1 2.0 1 1 1 2 2 2 0 GAGE protein p450 PF00067.17 ETS77887.1 - 9e-51 172.8 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 ETS77889.1 - 8.1e-56 185.7 3.6 4e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.15 ETS77889.1 - 0.011 15.2 0.1 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex adh_short PF00106.20 ETS77890.1 - 3.9e-21 75.6 0.7 6.8e-20 71.6 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS77890.1 - 5.2e-16 59.1 0.2 2.5e-15 56.9 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS77890.1 - 1e-09 38.3 0.3 3.1e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 KR domain LacAB_rpiB PF02502.13 ETS77890.1 - 0.012 15.2 0.8 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 Ribose/Galactose Isomerase Shikimate_DH PF01488.15 ETS77890.1 - 0.046 13.8 0.2 0.082 13.0 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 ETS77890.1 - 0.047 12.6 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase BUD22 PF09073.5 ETS77891.1 - 7.7e-75 252.5 52.1 5.7e-74 249.7 36.1 1.9 1 1 0 1 1 1 1 BUD22 PI3K_1B_p101 PF10486.4 ETS77891.1 - 2 5.8 11.4 0.02 12.4 2.6 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF482 PF04339.7 ETS77892.1 - 0.14 10.9 1.2 0.25 10.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF482 DUF2730 PF10805.3 ETS77893.1 - 0.0013 18.4 27.7 0.51 10.1 4.0 6.8 3 3 4 7 7 7 3 Protein of unknown function (DUF2730) FtsK_SpoIIIE PF01580.13 ETS77893.1 - 0.039 13.4 0.2 0.039 13.4 0.1 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Baculo_PEP_C PF04513.7 ETS77893.1 - 1.4 8.7 36.0 0.032 14.0 1.2 5.2 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRAUB PF08164.7 ETS77894.1 - 8.6e-30 102.6 0.2 8.6e-30 102.6 0.1 3.1 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 ETS77894.1 - 1.6e-24 86.5 4.0 1.6e-24 86.5 2.8 3.4 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor ParA PF10609.4 ETS77895.1 - 3.9e-34 116.3 0.9 8.9e-34 115.2 0.6 1.7 1 1 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS77895.1 - 1.5e-15 57.1 0.0 2.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS77895.1 - 1.5e-10 41.2 0.0 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 ETS77895.1 - 1.7e-06 27.7 0.2 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.10 ETS77895.1 - 8.1e-06 25.0 0.8 0.00016 20.8 0.2 2.5 1 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 ETS77895.1 - 2.2e-05 23.6 0.0 3.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 ETS77895.1 - 0.00043 19.5 0.0 0.03 13.4 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 ETS77895.1 - 0.0035 16.7 0.2 0.0091 15.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS77895.1 - 0.017 14.8 0.9 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain YhjQ PF06564.7 ETS77895.1 - 0.033 13.5 0.2 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein ArgK PF03308.11 ETS77895.1 - 0.051 12.3 0.1 0.051 12.3 0.1 1.6 2 0 0 2 2 2 0 ArgK protein FTHFS PF01268.14 ETS77895.1 - 0.077 10.9 0.0 0.11 10.4 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase VirC1 PF07015.6 ETS77895.1 - 0.085 11.9 0.2 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein DUF4537 PF15057.1 ETS77896.1 - 0.0051 16.5 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Fis1_TPR_C PF14853.1 ETS77896.1 - 0.091 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Rad9_Rad53_bind PF08605.5 ETS77896.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DUF2360 PF10152.4 ETS77896.1 - 4.4 7.5 12.4 8.8 6.6 1.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Glyco_hydro_28 PF00295.12 ETS77897.1 - 1.7e-112 375.5 18.7 2e-112 375.3 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.4 ETS77897.1 - 0.013 15.2 0.3 0.058 13.2 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) AcetylCoA_hyd_C PF13336.1 ETS77897.1 - 0.19 11.3 2.1 0.4 10.3 0.5 2.1 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Peptidase_M35 PF02102.10 ETS77898.1 - 5.5e-25 87.7 13.8 7.1e-25 87.4 9.6 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 ETS77898.1 - 7.5e-07 29.7 1.6 1.1e-06 29.2 0.2 2.0 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF1859 PF08948.5 ETS77898.1 - 0.068 12.9 0.4 0.27 10.9 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1859) NMT1 PF09084.6 ETS77899.1 - 5.7e-75 251.6 0.0 7.2e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 ETS77899.1 - 5.7e-07 29.1 0.4 0.19 11.1 0.0 3.2 2 1 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.2 ETS77899.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 ETS77899.1 - 0.13 11.1 0.0 2.2 7.1 0.0 2.1 1 1 0 2 2 2 0 PBP superfamily domain FAD_binding_3 PF01494.14 ETS77900.1 - 2.9e-25 89.0 0.0 5e-25 88.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS77900.1 - 2.2e-09 36.6 0.2 0.0001 21.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS77900.1 - 4e-08 33.5 0.0 3.3e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77900.1 - 0.00021 21.2 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS77900.1 - 0.0069 15.2 0.1 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS77900.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 ETS77900.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETS77900.1 - 0.026 14.3 0.1 0.076 12.8 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS77900.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS77900.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 ETS77900.1 - 0.089 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS77900.1 - 0.097 11.7 0.1 0.35 9.8 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 ETS77900.1 - 0.099 11.4 0.0 8.3 5.1 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 ETS77900.1 - 0.12 10.8 0.1 2.3 6.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Zn_clus PF00172.13 ETS77901.1 - 6.6e-10 38.7 8.3 9.3e-10 38.2 5.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS77902.1 - 5.3e-15 54.9 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3488 PF11992.3 ETS77903.1 - 0.064 11.8 0.1 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Pro-kuma_activ PF09286.6 ETS77904.1 - 5.8e-42 143.1 0.0 9.4e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS77904.1 - 0.0011 18.1 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Subtilase family 2-Hacid_dh_C PF02826.14 ETS77905.1 - 1.1e-43 148.4 0.0 2.7e-42 143.9 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS77905.1 - 5.6e-07 29.0 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS77905.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 ETS77907.1 - 7.3e-17 61.7 0.0 1.9e-16 60.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS77907.1 - 2.8e-06 27.1 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS77907.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 ETS77909.1 - 1e-13 50.7 1.6 1.8e-13 49.9 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain PROCT PF08084.6 ETS77909.1 - 0.15 11.7 0.1 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 PROCT (NUC072) domain IncA PF04156.9 ETS77914.1 - 0.0087 15.6 7.2 0.015 14.9 5.0 1.3 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 ETS77914.1 - 0.04 13.7 8.8 0.03 14.1 4.5 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Rootletin PF15035.1 ETS77914.1 - 0.059 13.3 10.7 0.11 12.4 7.4 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Sec2p PF06428.6 ETS77914.1 - 0.11 12.3 5.9 0.27 11.1 4.1 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF972 PF06156.8 ETS77914.1 - 0.16 12.3 3.2 0.34 11.2 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETS77914.1 - 0.16 10.9 10.2 0.31 10.0 7.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 ETS77914.1 - 0.43 10.3 7.8 0.91 9.2 5.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 ETS77914.1 - 0.83 8.5 4.9 1.6 7.6 3.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_CLD_2 PF14197.1 ETS77914.1 - 1.5 8.8 8.5 0.45 10.4 2.2 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF724 PF05266.9 ETS77914.1 - 1.6 8.3 6.9 0.84 9.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Reo_sigmaC PF04582.7 ETS77915.1 - 0.00044 19.5 15.1 0.074 12.2 3.8 3.5 3 1 0 3 3 3 3 Reovirus sigma C capsid protein Filament PF00038.16 ETS77915.1 - 0.095 12.1 59.9 0.23 10.8 9.9 4.3 1 1 3 4 4 4 0 Intermediate filament protein DUF3584 PF12128.3 ETS77915.1 - 4.8 4.3 63.0 1.9 5.7 20.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) p450 PF00067.17 ETS77916.1 - 4.1e-62 210.2 0.0 5.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 ETS77917.1 - 3.4e-17 62.2 0.0 5.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS77917.1 - 1.9e-06 28.7 0.0 6e-06 27.1 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase P22_Cro PF14549.1 ETS77917.1 - 0.00024 20.7 0.0 0.00056 19.5 0.0 1.6 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro PSI_PSAK PF01241.13 ETS77917.1 - 0.22 11.5 1.5 15 5.6 0.4 2.5 1 1 1 2 2 2 0 Photosystem I psaG / psaK zf-C2H2 PF00096.21 ETS77918.1 - 0.01 16.1 1.2 6.3 7.3 0.3 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETS77918.1 - 0.018 14.9 1.1 9.8 6.2 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger GMC_oxred_N PF00732.14 ETS77919.1 - 1.6e-59 201.5 0.0 4.2e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS77919.1 - 5.2e-37 127.3 0.0 9.7e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS77919.1 - 8.7e-07 28.1 0.1 2.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS77919.1 - 1.6e-06 27.2 0.0 0.0018 17.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS77919.1 - 0.00012 22.0 0.2 0.00036 20.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS77919.1 - 0.0013 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS77919.1 - 0.0057 16.7 0.1 0.046 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77919.1 - 0.0078 16.1 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77919.1 - 0.048 12.7 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 ETS77919.1 - 0.061 11.9 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 ETS77919.1 - 0.088 11.2 0.4 0.16 10.3 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 ETS77919.1 - 0.13 11.1 0.3 0.45 9.3 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_S10 PF00450.17 ETS77920.1 - 1.4e-83 281.3 3.2 2.4e-83 280.6 2.2 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase OEP PF02321.13 ETS77920.1 - 0.25 10.9 0.7 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein ABC1 PF03109.11 ETS77922.1 - 5.1e-25 87.7 0.0 4.7e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 ETS77922.1 - 0.0011 18.7 0.1 0.0039 16.9 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETS77922.1 - 0.1 11.9 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.12 ETS77923.1 - 2.3e-78 263.3 0.1 2.8e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SAM_2 PF07647.12 ETS77925.1 - 0.14 11.9 0.3 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HET PF06985.6 ETS77926.1 - 1.2e-33 116.2 0.1 2.4e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 ETS77927.1 - 6e-23 80.8 2.0 6e-23 80.8 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain ADH_N PF08240.7 ETS77928.1 - 1.1e-17 63.7 0.0 2.6e-17 62.5 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS77928.1 - 8.8e-08 31.7 0.0 2.3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sda PF08970.5 ETS77929.1 - 0.065 12.7 0.5 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A CcdA PF07362.7 ETS77929.1 - 0.092 12.6 4.1 0.12 12.2 0.3 2.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Ank_2 PF12796.2 ETS77930.1 - 1.2e-19 70.4 0.0 2.4e-12 47.0 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS77930.1 - 7.6e-19 66.5 2.2 1.2e-07 31.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 ETS77930.1 - 3.8e-15 54.4 0.2 3.6e-06 26.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS77930.1 - 8.9e-15 54.7 0.7 0.0032 17.9 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS77930.1 - 7.3e-14 51.4 1.6 3.5e-05 23.8 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Sugar_tr PF00083.19 ETS77931.1 - 1.7e-105 353.1 15.4 2.2e-105 352.8 10.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS77931.1 - 5.2e-25 87.8 17.3 5.2e-25 87.8 12.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF554 PF04474.7 ETS77931.1 - 0.77 8.8 7.8 0.058 12.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF554) PAP_assoc PF03828.14 ETS77932.1 - 1e-12 47.7 1.0 5e-12 45.5 0.0 2.5 2 1 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETS77932.1 - 4.1e-05 23.8 0.0 9.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Auxin_repressed PF05564.7 ETS77933.1 - 0.081 13.5 0.8 0.15 12.7 0.5 1.5 1 1 0 1 1 1 0 Dormancy/auxin associated protein RCC1 PF00415.13 ETS77937.1 - 1.6e-55 185.0 9.2 2.2e-10 40.5 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS77937.1 - 3.5e-35 118.8 25.3 1.9e-09 36.8 0.5 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat GAGA_bind PF06217.7 ETS77937.1 - 0.029 14.3 8.4 0.045 13.7 5.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF966 PF06136.8 ETS77937.1 - 2.4 7.5 11.1 4.6 6.5 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.4 ETS77937.1 - 7.7 5.0 21.7 10 4.5 15.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dehydratase_hem PF13816.1 ETS77939.1 - 1.4e-82 277.2 0.0 1.6e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase HAD_2 PF13419.1 ETS77940.1 - 1.2e-29 103.7 0.0 1.5e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TatD_DNase PF01026.16 ETS77941.1 - 5.9e-39 133.8 0.0 6.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase HEAT_2 PF13646.1 ETS77942.1 - 4.6e-26 90.9 28.9 1.6e-10 41.1 0.6 5.3 3 1 3 6 6 6 5 HEAT repeats NACHT PF05729.7 ETS77942.1 - 6.8e-19 68.1 0.6 9.2e-18 64.4 0.0 3.0 3 1 0 3 3 3 1 NACHT domain HEAT PF02985.17 ETS77942.1 - 2.3e-11 42.7 5.5 0.018 15.0 0.0 7.7 8 0 0 8 8 6 2 HEAT repeat NB-ARC PF00931.17 ETS77942.1 - 2.5e-11 42.9 0.0 5.9e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain HEAT_EZ PF13513.1 ETS77942.1 - 1.4e-07 31.7 13.7 0.00017 21.9 0.9 5.7 4 2 2 6 6 6 2 HEAT-like repeat Abhydrolase_6 PF12697.2 ETS77942.1 - 1.4e-05 25.0 0.0 7.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Adaptin_N PF01602.15 ETS77942.1 - 1.6e-05 23.4 1.3 3.5e-05 22.3 0.9 1.5 1 0 0 1 1 1 1 Adaptin N terminal region AAA_22 PF13401.1 ETS77942.1 - 3.8e-05 23.8 0.0 0.00023 21.2 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS77942.1 - 0.00025 21.3 0.0 0.00077 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS77942.1 - 0.00029 20.9 0.0 0.011 15.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_17 PF13207.1 ETS77942.1 - 0.00082 20.1 0.0 0.0045 17.7 0.0 2.5 1 0 0 1 1 1 1 AAA domain Cohesin_HEAT PF12765.2 ETS77942.1 - 0.0017 18.2 6.8 1 9.4 0.3 6.3 6 1 1 7 7 7 1 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 ETS77942.1 - 0.0027 17.5 1.4 3.8 7.4 0.1 4.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) AAA_14 PF13173.1 ETS77942.1 - 0.0068 16.3 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS77942.1 - 0.014 15.3 3.9 0.052 13.5 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain DUF676 PF05057.9 ETS77942.1 - 0.029 13.6 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NTPase_1 PF03266.10 ETS77942.1 - 0.035 13.8 0.1 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 NTPase Cnd1 PF12717.2 ETS77942.1 - 0.064 13.1 0.4 1.2 8.9 0.1 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.24 ETS77942.1 - 0.07 13.3 0.0 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 ETS77942.1 - 0.089 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 ETS77942.1 - 0.12 12.0 0.0 0.44 10.2 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 ETS77942.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CBM_20 PF00686.14 ETS77943.1 - 6.5e-25 86.5 0.2 1.3e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 ETS77943.1 - 1.2e-08 35.4 0.1 3e-06 27.6 0.0 2.5 1 1 0 1 1 1 1 Chitin binding domain Big_3_4 PF13754.1 ETS77943.1 - 0.0032 17.7 3.3 0.0032 17.7 2.3 3.5 4 1 0 4 4 4 1 Bacterial Ig-like domain (group 3) CBM_48 PF02922.13 ETS77943.1 - 0.058 13.4 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3157 PF11355.3 ETS77943.1 - 0.14 11.4 0.6 0.23 10.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Oxysterol_BP PF01237.13 ETS77944.1 - 6.8e-74 248.4 0.0 8.8e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein FlgD_ig PF13860.1 ETS77944.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain FAM60A PF15396.1 ETS77944.1 - 0.1 12.3 0.3 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A KIAA1430 PF13879.1 ETS77945.1 - 0.011 16.1 2.2 0.019 15.3 1.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DMPK_coil PF08826.5 ETS77945.1 - 0.48 10.3 4.1 0.68 9.8 2.1 1.9 1 1 0 1 1 1 0 DMPK coiled coil domain like IBR PF01485.16 ETS77946.1 - 4e-13 49.0 25.3 5.8e-12 45.3 2.7 3.4 3 0 0 3 3 3 2 IBR domain Hydantoinase_A PF01968.13 ETS77946.1 - 0.023 13.8 0.2 0.63 9.0 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 ETS77946.1 - 0.046 12.9 0.2 0.11 11.7 0.2 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF4246 PF14033.1 ETS77946.1 - 0.059 11.9 3.2 0.093 11.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Orbi_VP6 PF01516.11 ETS77946.1 - 0.64 9.0 7.2 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Orbivirus helicase VP6 Atrophin-1 PF03154.10 ETS77946.1 - 4.8 5.1 15.3 7 4.6 10.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Cellulase PF00150.13 ETS77947.1 - 1.1e-08 34.6 0.1 1.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HET PF06985.6 ETS77948.1 - 1e-27 97.0 0.1 1.6e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VCBS PF13517.1 ETS77949.1 - 5.8e-06 26.5 17.7 0.00017 21.9 3.2 4.9 4 2 2 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS77949.1 - 8.4e-05 22.1 20.3 0.076 12.7 0.8 4.8 4 0 0 4 4 4 3 FG-GAP repeat DUF1446 PF07287.6 ETS77950.1 - 1.6e-102 342.7 5.6 7e-101 337.2 3.9 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) LYTB PF02401.13 ETS77950.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 LytB protein ComA PF02679.10 ETS77950.1 - 0.12 11.4 0.0 0.52 9.2 0.0 2.0 1 1 1 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) AMP-binding PF00501.23 ETS77951.1 - 1.5e-70 237.7 0.0 1.9e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS77951.1 - 0.00013 22.8 0.0 0.00029 21.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1446 PF07287.6 ETS77952.1 - 2.1e-125 417.9 0.4 2.5e-125 417.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) MaoC_dehydratas PF01575.14 ETS77953.1 - 3.2e-24 84.6 0.0 4.9e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 ETS77953.1 - 4.3e-09 36.2 0.0 8e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ECH PF00378.15 ETS77954.1 - 5.5e-27 94.4 0.0 1.7e-18 66.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 ETS77955.1 - 1.3e-52 178.3 0.0 1.6e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TRI12 PF06609.8 ETS77956.1 - 3.7e-73 246.7 23.4 4.8e-73 246.3 16.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS77956.1 - 1e-26 93.5 60.7 2.3e-25 89.0 37.5 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77956.1 - 5e-07 28.6 10.0 5e-07 28.6 6.9 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter SieB PF14163.1 ETS77956.1 - 7 6.2 6.3 7.8 6.0 0.6 3.0 3 0 0 3 3 3 0 Superinfection exclusion protein B DUF3425 PF11905.3 ETS77957.1 - 8.2e-19 67.8 3.5 1.6e-18 66.9 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS77957.1 - 3.9e-05 23.5 3.7 0.022 14.6 0.5 2.9 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 ETS77957.1 - 0.00087 19.0 4.3 0.018 14.8 0.1 2.5 2 0 0 2 2 2 2 Basic region leucine zipper Shugoshin_N PF07558.6 ETS77957.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 ETS77957.1 - 0.096 12.9 1.9 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) BBE PF08031.7 ETS77958.1 - 0.014 15.2 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.18 ETS77959.1 - 4.2e-25 87.8 1.8 6.4e-25 87.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain P5CR_dimer PF14748.1 ETS77962.1 - 2.4e-38 130.4 0.6 4.5e-38 129.5 0.4 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 ETS77962.1 - 5.7e-20 71.5 0.5 1.4e-19 70.3 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 ETS77962.1 - 9.7e-05 22.1 3.5 0.0015 18.2 2.4 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 ETS77962.1 - 0.001 18.9 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 ETS77962.1 - 0.0034 16.3 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_7 PF13241.1 ETS77962.1 - 0.038 14.2 0.1 0.091 13.0 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETS77962.1 - 0.078 13.0 0.6 0.19 11.8 0.4 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HET PF06985.6 ETS77963.1 - 1.4e-17 64.2 11.4 2e-14 53.9 3.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TRI12 PF06609.8 ETS77964.1 - 2.3e-34 118.5 28.9 2.8e-34 118.2 20.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS77964.1 - 3e-20 72.2 50.9 3e-20 72.2 35.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS77964.1 - 4.3e-07 28.8 43.9 8.2e-07 27.9 10.1 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 ETS77964.1 - 0.37 10.2 14.1 0.015 14.8 3.8 2.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_3 PF01494.14 ETS77965.1 - 6.8e-24 84.5 0.7 3.7e-23 82.1 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS77965.1 - 8e-10 38.1 1.2 0.0001 21.3 0.2 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS77965.1 - 2.2e-06 27.0 0.2 0.0051 15.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS77965.1 - 4.2e-05 23.5 0.3 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS77965.1 - 0.00014 20.4 0.1 0.09 11.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 ETS77965.1 - 0.00038 20.5 1.1 0.0029 17.6 0.8 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS77965.1 - 0.0028 16.6 1.2 0.028 13.3 0.8 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 ETS77965.1 - 0.0029 17.9 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS77965.1 - 0.011 15.6 0.1 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transpep_BrtH PF14399.1 ETS77965.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase FAD_oxidored PF12831.2 ETS77965.1 - 0.046 12.7 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS77965.1 - 0.1 12.3 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_transf_28 PF03033.15 ETS77967.1 - 3.4e-18 65.7 0.2 1.1e-17 64.1 0.2 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS77967.1 - 0.00076 18.1 0.0 0.0013 17.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS77967.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 ETS77967.1 - 0.035 14.2 0.1 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 ATG C terminal domain RTA1 PF04479.8 ETS77968.1 - 2.7e-57 193.8 16.3 4.2e-57 193.2 11.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 ETS77968.1 - 0.59 9.7 8.9 0.03 13.9 2.0 1.9 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Zn_clus PF00172.13 ETS77969.1 - 4.6e-07 29.6 1.3 1e-06 28.4 0.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS77969.1 - 0.02 13.4 1.3 0.039 12.5 0.9 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.17 ETS77970.1 - 2.7e-35 121.8 0.1 3.3e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 ETS77972.1 - 2.1e-48 164.8 11.1 2.8e-48 164.3 7.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Peptidase_U4 PF03419.8 ETS77972.1 - 2.3 7.2 9.5 1.4 7.9 1.7 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Bac_rhamnosid PF05592.6 ETS77973.1 - 1.2e-28 99.6 0.0 1.8e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS77973.1 - 0.00024 19.9 1.8 0.00037 19.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 DUF1080 PF06439.6 ETS77973.1 - 0.00048 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_3 PF13385.1 ETS77973.1 - 0.0027 17.9 0.2 0.0092 16.2 0.1 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ion_trans PF00520.26 ETS77974.1 - 9.5e-07 28.2 12.8 9.5e-07 28.2 8.8 2.0 2 0 0 2 2 2 1 Ion transport protein BPL_N PF09825.4 ETS77975.1 - 1.3e-138 461.7 0.0 1.6e-138 461.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 ETS77975.1 - 1e-19 70.7 0.0 1.9e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Mgm101p PF06420.7 ETS77976.1 - 6.8e-87 289.1 0.0 8.7e-87 288.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.14 ETS77977.1 - 7e-29 99.4 7.7 1e-28 98.9 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 7TM_GPCR_Srv PF10323.4 ETS77978.1 - 0.0005 19.2 0.1 0.0027 16.8 0.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Bac_rhodopsin PF01036.13 ETS77978.1 - 0.21 10.8 4.5 0.052 12.8 0.9 1.7 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein Tmemb_9 PF05434.6 ETS77978.1 - 2.4 7.9 5.2 10 5.8 0.0 2.9 2 1 1 3 3 3 0 TMEM9 Abhydrolase_3 PF07859.8 ETS77981.1 - 4.3e-34 117.9 0.0 7.3e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS77981.1 - 9.3e-07 27.9 0.0 7.4e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS77981.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 ETS77981.1 - 0.0061 15.1 0.0 0.009 14.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 ETS77981.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain RAP1 PF07218.6 ETS77982.1 - 0.032 12.3 2.1 0.042 11.9 1.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.8 ETS77982.1 - 0.19 11.7 5.9 11 6.0 2.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 ETS77982.1 - 1.1 7.4 9.5 0.44 8.7 4.1 1.8 2 0 0 2 2 2 0 Transmembrane protein SelP_N PF04592.9 ETS77982.1 - 2.4 7.4 16.7 3.1 7.0 1.3 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region MIP-T3 PF10243.4 ETS77982.1 - 3.1 6.1 14.1 3.9 5.8 8.3 1.8 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 Dioxygenase_C PF00775.16 ETS77983.1 - 5.3e-09 35.5 0.5 1.5e-08 34.1 0.3 1.7 1 1 0 1 1 1 1 Dioxygenase FMO-like PF00743.14 ETS77984.1 - 3.6e-53 180.5 0.0 4.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS77984.1 - 2.7e-22 79.8 0.0 5.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS77984.1 - 3.8e-09 35.9 0.0 3.6e-07 29.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS77984.1 - 1.4e-08 34.8 0.0 1.9e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS77984.1 - 6.1e-07 29.3 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS77984.1 - 1.2e-06 28.4 0.0 0.00012 21.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 ETS77984.1 - 0.00093 19.2 0.1 0.0044 17.0 0.0 2.2 3 0 0 3 3 2 1 NADH(P)-binding Pyr_redox PF00070.22 ETS77984.1 - 0.0016 18.8 0.0 1.6 9.1 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS77984.1 - 0.0069 15.5 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 ETS77984.1 - 0.01 15.9 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS77984.1 - 0.015 15.4 0.0 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 ETS77984.1 - 0.022 14.3 0.0 0.074 12.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 ETS77984.1 - 0.03 14.1 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 ETS77984.1 - 0.056 12.6 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 ETS77984.1 - 0.11 11.4 0.0 0.25 10.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 ETS77984.1 - 0.11 12.4 0.0 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 ETS77984.1 - 0.12 11.7 0.0 1.6 8.0 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ETS77984.1 - 0.13 12.7 0.0 22 5.5 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.9 ETS77984.1 - 0.17 10.3 0.0 1.1 7.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein RNase_H PF00075.19 ETS77985.1 - 1.1e-05 25.7 0.0 7.2e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 RNase H Fungal_trans_2 PF11951.3 ETS77986.1 - 0.00017 20.3 3.8 0.0031 16.1 0.2 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain GST_N_3 PF13417.1 ETS77987.1 - 4.7e-12 45.9 0.0 9.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS77987.1 - 5.9e-12 45.6 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS77987.1 - 9.1e-11 41.6 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS77987.1 - 9.1e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS77987.1 - 9.8e-05 22.7 0.1 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS77987.1 - 0.0014 18.5 0.0 0.0035 17.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 ETS77988.1 - 1.6e-52 178.5 0.0 2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS77989.1 - 4.5e-31 107.8 32.3 4.5e-31 107.8 22.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1127 PF06568.6 ETS77989.1 - 0.44 9.9 3.2 1 8.8 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) HTH_psq PF05225.11 ETS77990.1 - 1.4e-19 69.3 0.2 3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 ETS77990.1 - 1.2e-10 41.0 0.1 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.15 ETS77990.1 - 0.00021 21.1 0.4 0.12 12.3 0.0 3.1 2 1 1 3 3 3 2 Transposase HTH_28 PF13518.1 ETS77990.1 - 0.013 15.4 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 ETS77990.1 - 0.1 12.2 0.5 21 4.9 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain NMT1 PF09084.6 ETS77991.1 - 3.3e-11 43.1 0.3 7.2e-11 42.0 0.2 1.6 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 ETS77991.1 - 0.00022 20.5 0.2 0.00036 19.8 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 ETS77991.1 - 0.0011 18.4 0.5 0.0018 17.7 0.3 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_7 PF03480.8 ETS77991.1 - 0.024 13.7 0.0 0.066 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Rax2 PF12768.2 ETS77992.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.5 ETS77992.1 - 0.0004 19.6 1.0 0.00091 18.4 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Pam16 PF03656.8 ETS77993.1 - 5.5e-32 110.2 0.9 6.4e-32 110.0 0.6 1.0 1 0 0 1 1 1 1 Pam16 DUF2884 PF11101.3 ETS77993.1 - 0.0003 20.2 0.4 0.0004 19.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) DUF1110 PF06533.7 ETS77993.1 - 0.0071 16.1 0.2 0.0096 15.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1110) Yip1 PF04893.12 ETS77994.1 - 1.3e-06 28.0 15.0 0.007 15.8 0.2 2.4 2 1 0 2 2 2 2 Yip1 domain IL11 PF07400.6 ETS77994.1 - 0.14 11.6 0.6 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Interleukin 11 Glyco_hydro_61 PF03443.9 ETS77995.1 - 1.3e-61 208.2 0.6 1.7e-61 207.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4165 PF13752.1 ETS77995.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Chal_sti_synt_C PF02797.10 ETS77996.1 - 2.6e-23 82.5 0.0 6.1e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 ETS77996.1 - 2.4e-22 79.3 0.3 3.7e-22 78.6 0.2 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 ETS77996.1 - 3.8e-07 29.4 0.0 5.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 ETS77996.1 - 1.9e-06 27.7 0.0 3.1e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 ETS77996.1 - 0.0084 15.7 0.2 0.044 13.4 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 ETS77997.1 - 8.2e-23 80.6 0.0 3.8e-22 78.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Cad PF03596.8 ETS77998.1 - 1e-30 106.8 9.0 1.5e-30 106.3 6.3 1.2 1 0 0 1 1 1 1 Cadmium resistance transporter Methyltransf_23 PF13489.1 ETS77999.1 - 1.3e-05 25.0 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS77999.1 - 2e-05 24.2 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS77999.1 - 6.5e-05 23.2 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS77999.1 - 0.00038 20.8 0.0 0.00079 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS77999.1 - 0.0044 17.4 0.1 0.0077 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1996 PF09362.5 ETS78000.1 - 3.5e-78 262.5 3.7 4.5e-78 262.1 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fe-ADH PF00465.14 ETS78001.1 - 1.1e-62 211.7 0.0 1.4e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 ETS78001.1 - 6.6e-06 25.6 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase RRM_1 PF00076.17 ETS78002.1 - 2.7e-09 36.5 0.2 4.7e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS78002.1 - 5e-07 29.6 0.0 9.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS78002.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS78002.1 - 0.0031 17.2 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2046 PF09755.4 ETS78004.1 - 0.01 14.7 1.3 0.047 12.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.7 ETS78004.1 - 0.071 13.4 5.0 0.2 11.9 0.0 2.6 2 1 0 2 2 2 0 Striatin family Phage_lysis PF03245.8 ETS78004.1 - 0.085 12.8 0.2 0.085 12.8 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Kinetocho_Slk19 PF12709.2 ETS78004.1 - 3.7 7.6 5.6 0.97 9.5 1.4 1.8 2 0 0 2 2 2 0 Central kinetochore-associated DivIC PF04977.10 ETS78004.1 - 4.8 6.7 5.2 0.68 9.4 0.8 1.6 2 0 0 2 2 2 0 Septum formation initiator p450 PF00067.17 ETS78006.1 - 3e-67 227.1 0.0 3.8e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS78008.1 - 4.2e-35 121.0 23.7 4.2e-35 121.0 16.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.8 ETS78008.1 - 0.13 11.3 1.9 0.26 10.2 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Abhydrolase_3 PF07859.8 ETS78009.1 - 9.5e-62 208.3 0.0 1.3e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS78009.1 - 7.6e-08 31.5 0.0 1.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS78009.1 - 2.8e-05 23.4 0.0 4.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS78009.1 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS78009.1 - 0.0033 16.1 0.0 0.012 14.2 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2424) Glyco_hydro_81 PF03639.8 ETS78010.1 - 4.5e-210 699.2 10.9 5.7e-210 698.9 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Stn1 PF10451.4 ETS78011.1 - 1.5e-17 63.3 2.7 2.5e-08 33.1 0.5 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 ETS78011.1 - 0.00043 20.0 0.1 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAN_1 PF00024.21 ETS78013.1 - 6e-05 22.7 1.4 0.0001 22.0 1.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 ETS78013.1 - 0.0016 18.1 2.9 0.0035 16.9 2.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 ETS78013.1 - 0.022 14.3 0.6 0.039 13.5 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.6 ETS78013.1 - 0.033 14.0 0.3 0.057 13.2 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain GCFC PF07842.7 ETS78013.1 - 0.069 12.4 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DnaJ PF00226.26 ETS78014.1 - 1.4e-23 82.4 4.7 1.7e-23 82.1 0.9 2.6 2 1 0 2 2 2 1 DnaJ domain Sulfotransfer_2 PF03567.9 ETS78014.1 - 0.013 15.2 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Sulfotransferase family TarH PF02203.10 ETS78014.1 - 9.2 6.0 9.2 8.2 6.2 4.1 2.4 1 1 1 2 2 2 0 Tar ligand binding domain homologue dCMP_cyt_deam_1 PF00383.17 ETS78015.1 - 4.6e-14 51.9 0.0 6.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cellulase PF00150.13 ETS78016.1 - 3.5e-17 62.5 3.4 4.8e-17 62.0 2.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 ETS78016.1 - 4.5e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 ETS78016.1 - 0.00045 19.2 0.0 0.0026 16.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 ETS78016.1 - 0.0044 16.1 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 ETS78016.1 - 0.022 13.7 0.0 0.045 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 FAD_binding_4 PF01565.18 ETS78017.1 - 3.6e-27 94.5 0.2 5.5e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78017.1 - 0.0099 15.7 0.1 0.031 14.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 ETS78018.1 - 3.9e-57 193.8 0.0 5.5e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Alpha-L-AF_C PF06964.7 ETS78019.1 - 1.3e-30 106.4 0.0 2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 ETS78020.1 - 8.8e-75 251.9 28.0 1e-74 251.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78020.1 - 2.5e-23 82.3 27.5 1.1e-20 73.6 18.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS78020.1 - 0.00022 19.7 28.1 0.043 12.2 0.3 3.9 3 1 1 4 4 4 4 MFS/sugar transport protein Herpes_UL17 PF04559.7 ETS78022.1 - 0.55 8.7 3.3 0.66 8.4 2.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein zf-RING_2 PF13639.1 ETS78023.1 - 2.4e-11 43.2 3.9 3.7e-11 42.6 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS78023.1 - 7.7e-07 29.1 1.4 7.7e-07 29.1 1.0 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS78023.1 - 1.4e-05 24.8 1.0 2.6e-05 23.9 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETS78023.1 - 3.8e-05 23.2 1.0 6.6e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS78023.1 - 0.00014 21.7 3.8 0.00023 21.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS78023.1 - 0.00035 20.1 2.1 0.00058 19.4 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 ETS78023.1 - 0.0027 17.1 4.8 0.006 16.0 0.1 2.8 2 1 1 3 3 3 1 Rad50 zinc hook motif zf-RING_5 PF14634.1 ETS78023.1 - 0.0039 16.9 1.1 0.0068 16.1 0.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.1 ETS78023.1 - 0.0056 16.4 1.1 0.031 14.0 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-Di19 PF05605.7 ETS78023.1 - 0.025 14.6 1.4 8.2 6.6 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 ETS78023.1 - 0.088 12.4 5.2 0.91 9.1 3.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 ETS78023.1 - 0.16 11.9 1.8 4 7.4 1.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 ETS78023.1 - 1.4 8.6 8.2 16 5.3 0.2 3.5 3 0 0 3 3 3 0 RING-type zinc-finger DUF723 PF05265.8 ETS78023.1 - 2.5 7.9 4.4 0.4 10.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF723) zf-C3HC4_4 PF15227.1 ETS78023.1 - 3 7.8 5.6 6.5 6.7 3.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Acetyltransf_1 PF00583.19 ETS78024.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS78024.1 - 9e-06 25.5 0.0 0.08 12.8 0.0 3.0 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS78024.1 - 0.00038 20.2 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 ETS78024.1 - 0.00061 19.9 0.0 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS78024.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS78024.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein FAD_binding_4 PF01565.18 ETS78025.1 - 5e-19 68.1 2.8 9.9e-19 67.1 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78025.1 - 7.9e-10 38.4 0.7 2e-09 37.1 0.5 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS78025.1 - 0.0054 15.9 0.1 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ketoacyl-synt PF00109.21 ETS78026.1 - 1.9e-71 240.5 0.2 2e-70 237.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS78026.1 - 1.7e-31 108.5 0.6 4.4e-31 107.2 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 ETS78026.1 - 7.4e-29 101.0 1.4 7.1e-25 87.9 0.1 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 ETS78026.1 - 1.1e-23 83.8 0.0 1.7e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 ETS78026.1 - 2.1e-15 56.9 0.0 6.8e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 ETS78026.1 - 1.1e-14 54.5 0.0 5.4e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PP-binding PF00550.20 ETS78026.1 - 8.2e-12 45.2 3.2 2.4e-11 43.7 2.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 ETS78026.1 - 8.4e-12 45.1 0.0 3.8e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_5 PF12695.2 ETS78026.1 - 1.5e-10 40.9 0.1 2.1e-08 34.0 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78026.1 - 1.8e-08 34.5 4.4 1.9e-08 34.4 0.6 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 ETS78026.1 - 2e-08 33.9 0.0 5.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 ETS78026.1 - 2.4e-08 33.4 0.0 9.6e-05 21.6 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.18 ETS78026.1 - 1.2e-05 24.4 0.1 2.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 ETS78026.1 - 4.6e-05 23.7 0.0 0.00019 21.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS78026.1 - 0.00041 20.7 0.0 0.0021 18.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78026.1 - 0.001 19.6 0.0 0.0061 17.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Thioesterase PF00975.15 ETS78026.1 - 0.0038 17.4 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 1 1 Thioesterase domain COesterase PF00135.23 ETS78026.1 - 0.03 13.0 0.0 0.069 11.8 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family Ubie_methyltran PF01209.13 ETS78026.1 - 0.038 13.1 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS78026.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 ETS78026.1 - 0.23 10.8 0.0 0.51 9.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) ACP_syn_III PF08545.5 ETS78026.1 - 9 6.0 7.9 0.8 9.4 0.1 2.7 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_1 PF00583.19 ETS78027.1 - 9.3e-07 28.8 0.0 2.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS78027.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS78027.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS78027.1 - 0.0058 16.7 0.2 0.014 15.4 0.0 1.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS78027.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.11 ETS78028.1 - 1.8e-42 145.3 51.6 2.6e-39 134.9 37.4 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Piwi PF02171.12 ETS78029.1 - 3.2e-68 229.9 0.0 4.5e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 ETS78029.1 - 1.3e-08 34.1 0.0 2.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 ETS78029.1 - 1.9e-08 33.5 0.0 6.9e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Flavokinase PF01687.12 ETS78030.1 - 4.6e-37 126.6 0.0 5.5e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 ETS78031.1 - 0.0029 17.4 8.6 0.007 16.2 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 ETS78031.1 - 0.0055 16.4 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 ETS78031.1 - 0.15 12.4 0.0 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 PAS domain Cellulase PF00150.13 ETS78032.1 - 1.7e-11 43.8 2.2 3.3e-11 42.9 1.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 ETS78032.1 - 0.0004 20.7 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain OppC_N PF12911.2 ETS78032.1 - 0.016 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1191 PF06697.7 ETS78032.1 - 0.085 11.6 0.2 0.2 10.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3357 PF11837.3 ETS78032.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Transket_pyr PF02779.19 ETS78033.1 - 2.2e-44 151.0 0.0 3.7e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS78033.1 - 8.2e-34 116.2 0.2 2.7e-33 114.5 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain F-actin_cap_A PF01267.12 ETS78034.1 - 9.1e-93 310.2 0.0 1e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.23 ETS78035.1 - 2.1e-25 88.2 0.2 2.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.7 ETS78035.1 - 0.023 14.5 0.3 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TFIIE_beta PF02186.10 ETS78036.1 - 0.0011 18.9 1.4 0.0018 18.2 0.0 2.0 3 0 0 3 3 3 1 TFIIE beta subunit core domain Imm41 PF15583.1 ETS78036.1 - 0.042 13.6 0.5 5 6.9 0.0 2.7 3 0 0 3 3 3 0 Immunity protein 41 DSBA PF01323.15 ETS78037.1 - 9.3e-09 35.1 0.0 4.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 ETS78037.1 - 0.012 15.6 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin S-methyl_trans PF02574.11 ETS78037.1 - 0.043 13.1 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Homocysteine S-methyltransferase CUE PF02845.11 ETS78037.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 CUE domain CbiX PF01903.12 ETS78037.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 CbiX zf-C2H2 PF00096.21 ETS78038.1 - 5.8e-23 79.7 24.6 1.5e-05 25.0 0.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS78038.1 - 3.6e-21 74.3 29.0 3.1e-07 30.3 0.7 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS78038.1 - 6.9e-16 57.3 23.8 0.00028 20.9 2.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS78038.1 - 1e-05 25.4 6.0 1.5 9.0 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS78038.1 - 0.0021 17.8 15.8 1.4 8.8 0.8 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 ETS78038.1 - 0.016 14.8 6.8 1.2 8.9 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.2 ETS78038.1 - 0.018 15.2 15.2 2.1 8.6 0.0 5.2 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 ETS78038.1 - 0.078 12.9 11.0 7.8 6.5 1.3 4.1 2 1 1 3 3 3 0 Zinc ribbon domain XPA_N PF01286.13 ETS78038.1 - 0.089 12.4 0.3 0.089 12.4 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zinc_ribbon_2 PF13240.1 ETS78038.1 - 9.8 5.8 8.5 40 3.8 2.0 3.2 2 1 0 2 2 2 0 zinc-ribbon domain DHBP_synthase PF00926.14 ETS78039.1 - 9.6e-74 246.8 0.0 4e-73 244.7 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 ETS78040.1 - 1.7e-20 73.3 0.0 3.7e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS78040.1 - 4e-19 68.9 0.0 6.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78040.1 - 2.5e-17 62.8 0.0 3.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS78040.1 - 7.7e-15 55.1 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78040.1 - 2.8e-13 50.4 0.0 4.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS78040.1 - 9e-10 38.6 0.0 4.9e-09 36.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS78040.1 - 9.5e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS78040.1 - 4e-08 32.6 0.0 5.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 ETS78040.1 - 2.9e-07 29.9 0.0 4.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 ETS78040.1 - 6.6e-05 21.7 0.0 9.6e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 ETS78040.1 - 9.5e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ETS78040.1 - 0.00039 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 ETS78040.1 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) AA_permease PF00324.16 ETS78041.1 - 1.1e-101 340.5 45.8 1.4e-101 340.1 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS78041.1 - 5.3e-26 91.1 50.6 8.1e-26 90.5 35.1 1.3 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 ETS78041.1 - 0.004 16.6 0.1 0.045 13.3 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) DUF1625 PF07787.7 ETS78042.1 - 0.22 10.7 0.9 0.41 9.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Hexapep PF00132.19 ETS78045.1 - 3.4e-09 35.7 6.8 9.2e-07 28.1 1.3 3.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS78045.1 - 0.00018 20.9 8.2 0.23 11.0 2.6 3.1 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 ETS78046.1 - 2.3e-47 160.5 0.0 3.6e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 ETS78046.1 - 3.4e-18 64.5 1.0 3.4e-18 64.5 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 ETS78046.1 - 1.6e-09 37.5 0.0 4.4e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Rsa3 PF14615.1 ETS78048.1 - 0.035 13.3 0.1 0.93 8.8 0.0 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 Zona_pellucida PF00100.18 ETS78048.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain zf-CHY PF05495.7 ETS78049.1 - 8e-16 57.9 24.2 8.8e-15 54.6 9.7 3.3 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.17 ETS78049.1 - 4.3e-05 23.3 0.3 0.0068 16.2 0.0 2.6 2 0 0 2 2 2 2 RWD domain Mu-like_Com PF10122.4 ETS78049.1 - 0.00018 20.4 0.3 0.00018 20.4 0.2 2.8 3 0 0 3 3 3 1 Mu-like prophage protein Com UQ_con PF00179.21 ETS78049.1 - 0.11 11.8 0.2 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme GMC_oxred_N PF00732.14 ETS78050.1 - 1e-62 211.9 0.0 1.5e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS78050.1 - 1.2e-28 100.2 0.0 2.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS78050.1 - 1.2e-07 31.0 0.0 0.00091 18.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS78050.1 - 1.2e-07 30.9 0.1 0.01 14.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS78050.1 - 2.1e-05 24.4 0.1 6.5e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS78050.1 - 2.3e-05 24.5 0.0 0.048 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS78050.1 - 0.0011 18.8 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS78050.1 - 0.0049 16.0 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS78050.1 - 0.0098 16.2 0.0 0.14 12.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS78050.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS78050.1 - 0.039 12.8 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETS78050.1 - 0.23 10.2 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Tannase PF07519.6 ETS78051.1 - 2.5e-117 392.4 5.1 3.1e-117 392.2 3.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 ETS78051.1 - 0.00019 21.1 0.5 0.061 13.0 0.0 2.9 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78051.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_28 PF00295.12 ETS78052.1 - 1.6e-30 106.2 0.1 2.1e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 ETS78052.1 - 0.001 19.2 8.9 0.05 13.7 6.1 2.7 1 1 0 1 1 1 1 Pectate lyase superfamily protein Beta_helix PF13229.1 ETS78052.1 - 0.065 12.9 12.6 0.13 11.9 8.4 1.7 1 1 0 1 1 1 0 Right handed beta helix region Tannase PF07519.6 ETS78053.1 - 8.8e-99 331.3 0.6 1e-98 331.1 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS78053.1 - 8.1e-05 22.6 0.0 0.00026 20.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS78053.1 - 0.00011 21.9 0.3 0.24 11.1 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS78053.1 - 0.00015 21.0 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS78053.1 - 0.00089 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS78053.1 - 0.083 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Zn_clus PF00172.13 ETS78054.1 - 9.2e-06 25.4 1.9 2.1e-05 24.3 1.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS78054.1 - 0.00015 20.5 0.9 0.0002 20.0 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 ETS78055.1 - 7.2e-48 163.0 7.4 1.2e-47 162.2 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1129 PF06570.6 ETS78055.1 - 3.3 6.9 8.5 4.1 6.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HET PF06985.6 ETS78056.1 - 1.2e-26 93.4 0.0 2.6e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.16 ETS78057.1 - 1.3e-50 172.5 0.1 1e-48 166.2 0.1 2.2 1 1 0 1 1 1 1 Amidase Tannase PF07519.6 ETS78058.1 - 4e-41 141.2 0.1 1.5e-33 116.2 0.0 2.2 2 0 0 2 2 2 2 Tannase and feruloyl esterase Cellulase PF00150.13 ETS78058.1 - 1.9e-16 60.0 3.0 3.7e-16 59.1 2.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.2 ETS78059.1 - 2e-98 322.8 0.3 2.8e-15 56.4 0.0 10.5 3 2 7 11 11 11 9 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78059.1 - 1.7e-82 267.3 12.7 2.3e-08 33.4 0.0 19.3 19 0 0 19 19 19 15 Ankyrin repeat Ank_4 PF13637.1 ETS78059.1 - 4e-70 231.0 17.9 9.6e-11 41.9 0.1 14.7 10 5 6 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78059.1 - 8e-61 195.8 9.1 2.4e-05 24.1 0.0 19.0 18 0 0 18 18 18 13 Ankyrin repeat Ank_5 PF13857.1 ETS78059.1 - 2.5e-45 151.4 20.9 6.3e-07 29.4 0.1 15.3 9 3 6 15 15 15 12 Ankyrin repeats (many copies) Peptidase_S9 PF00326.16 ETS78059.1 - 0.034 13.3 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ZZ PF00569.12 ETS78059.1 - 0.18 11.3 13.5 0.044 13.3 6.6 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type Peptidase_S8 PF00082.17 ETS78061.1 - 4.2e-19 68.7 0.3 7.9e-19 67.8 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 ETS78061.1 - 2.9e-09 37.1 0.3 0.0014 19.0 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS78061.1 - 3.4e-08 33.7 1.8 0.0077 16.5 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78061.1 - 3.4e-08 32.8 0.7 0.085 12.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 ETS78061.1 - 1.6e-06 27.8 1.4 0.04 14.1 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 ETS78061.1 - 3.6e-05 23.8 0.6 1.9 8.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF3295 PF11702.3 ETS78062.1 - 1.8e-135 452.8 36.4 2.1e-135 452.5 25.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 ETS78062.1 - 3.5e-12 45.6 1.2 7.4e-12 44.6 0.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VHS PF00790.14 ETS78064.1 - 2.1e-25 89.0 0.0 1.1e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 ETS78064.1 - 1.7e-10 40.7 0.5 3.6e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 GAT domain Ion_trans_2 PF07885.11 ETS78066.1 - 5.5e-31 106.1 28.4 1.6e-17 62.9 3.6 3.2 3 1 0 3 3 3 2 Ion channel SieB PF14163.1 ETS78066.1 - 0.026 14.0 3.8 13 5.3 0.0 3.6 3 1 0 3 3 3 0 Superinfection exclusion protein B Ion_trans PF00520.26 ETS78066.1 - 8.9 5.5 17.8 0.1 11.8 1.1 2.8 2 1 0 2 2 2 0 Ion transport protein Abhydrolase_6 PF12697.2 ETS78067.1 - 7.3e-05 22.7 6.3 0.0003 20.7 4.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS78067.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Semialdhyde_dhC PF02774.13 ETS78068.1 - 5.3e-40 137.2 0.0 7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 ETS78068.1 - 7.6e-31 106.9 0.0 3.1e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS78068.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 ETS78068.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mucin PF01456.12 ETS78069.1 - 0.017 14.8 12.9 0.022 14.5 8.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ferric_reduct PF01794.14 ETS78069.1 - 0.1 12.6 0.1 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Mito_fiss_reg PF05308.6 ETS78069.1 - 0.1 11.9 10.6 0.16 11.3 7.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3439 PF11921.3 ETS78069.1 - 0.46 10.2 11.3 0.64 9.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MCPVI PF02993.9 ETS78069.1 - 1.5 8.9 5.4 1.7 8.7 3.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Dicty_REP PF05086.7 ETS78069.1 - 5.3 4.6 7.1 6.7 4.3 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn-ribbon_8 PF09723.5 ETS78070.1 - 0.051 13.5 0.8 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.1 ETS78070.1 - 0.11 12.0 1.5 2.8 7.5 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_76 PF03663.9 ETS78071.1 - 1.2e-148 495.4 14.5 1.6e-148 494.9 10.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.16 ETS78072.1 - 2.3e-28 97.6 1.1 2.5e-28 97.4 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1100 PF06500.6 ETS78072.1 - 0.097 11.2 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF619 PF04768.8 ETS78073.1 - 2.6e-47 160.3 0.2 5.1e-47 159.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 ETS78073.1 - 7.7e-30 103.6 0.0 2.1e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 ETS78073.1 - 5.9e-25 88.2 0.0 2.5e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family DapB_N PF01113.15 ETS78073.1 - 0.021 14.7 0.0 0.06 13.2 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GTP_EFTU PF00009.22 ETS78074.1 - 1.9e-47 161.1 0.0 3.2e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 ETS78074.1 - 9.6e-23 80.1 0.7 2.5e-22 78.7 0.5 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 ETS78074.1 - 3e-08 33.6 0.0 6.1e-07 29.4 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 ETS78074.1 - 1e-07 31.9 0.0 6.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 ETS78074.1 - 4.7e-06 26.6 0.1 3.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 ETS78074.1 - 9.2e-06 26.1 0.0 0.00024 21.5 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 ETS78074.1 - 0.00063 19.3 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 ETS78074.1 - 0.0076 15.4 0.0 0.54 9.4 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 ETS78074.1 - 0.02 14.1 0.9 3.3 6.8 0.0 2.6 2 1 1 3 3 3 0 ADP-ribosylation factor family FeoB_N PF02421.13 ETS78074.1 - 0.11 11.8 0.0 1.8 7.7 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 ETS78074.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin EF-hand_7 PF13499.1 ETS78075.1 - 1.1e-13 51.0 0.3 2.1e-06 27.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETS78075.1 - 1.1e-12 46.2 9.4 3e-05 22.9 0.4 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 ETS78075.1 - 3.6e-12 45.0 7.4 7e-06 25.5 0.5 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 ETS78075.1 - 2.5e-11 42.9 5.2 2.6e-06 26.9 0.5 3.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 ETS78075.1 - 0.00033 19.8 7.3 0.03 13.6 0.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 ETS78075.1 - 0.082 12.8 0.1 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.2 ETS78075.1 - 0.13 12.0 1.7 0.45 10.2 0.3 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Nup96 PF12110.3 ETS78076.1 - 1.4e-91 306.6 0.4 2e-91 306.1 0.3 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 ETS78076.1 - 5.3e-45 152.6 0.1 9.9e-45 151.8 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 ETS78076.1 - 1.2e-29 102.8 381.7 3.6e-11 43.2 39.2 11.6 3 2 5 8 8 8 5 Nucleoporin FG repeat region Cpn60_TCP1 PF00118.19 ETS78077.1 - 1.3e-145 485.7 3.3 1.5e-145 485.5 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 ETS78077.1 - 0.04 13.5 0.2 0.39 10.3 0.1 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Enolase_N PF03952.11 ETS78077.1 - 0.16 11.9 1.7 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF3176 PF11374.3 ETS78079.1 - 2e-27 95.2 0.8 5e-27 93.9 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RskA PF10099.4 ETS78079.1 - 1.4 8.6 4.9 4 7.1 0.1 3.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Glyco_hydro_43 PF04616.9 ETS78081.1 - 1.4e-39 135.9 9.0 1.9e-39 135.4 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 KR PF08659.5 ETS78082.1 - 3.9e-58 196.0 0.1 8.9e-58 194.9 0.1 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 ETS78082.1 - 1.1e-57 195.4 0.0 2.6e-57 194.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS78082.1 - 1.9e-53 181.8 0.0 3.1e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS78082.1 - 7.9e-45 152.7 0.2 4e-44 150.4 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 ETS78082.1 - 6.5e-41 140.4 0.0 6.5e-41 140.4 0.0 1.6 2 0 0 2 2 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 ETS78082.1 - 4.7e-35 120.0 0.0 1e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS78082.1 - 2.4e-17 63.1 0.0 6.2e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS78082.1 - 2.5e-17 62.6 0.4 7.1e-17 61.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 ETS78082.1 - 5.6e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78082.1 - 2.1e-11 43.6 0.0 7.7e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78082.1 - 2.7e-11 44.0 0.0 9.1e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS78082.1 - 1.8e-10 41.8 0.0 8.4e-10 39.6 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 ETS78082.1 - 7.1e-09 35.7 0.0 2.2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 ETS78082.1 - 4.7e-08 33.4 0.0 1.3e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS78082.1 - 5.4e-05 22.4 0.0 0.00014 21.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 ETS78082.1 - 9.3e-05 22.1 0.0 0.00028 20.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 ETS78082.1 - 0.00078 19.7 0.0 0.0028 17.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 ETS78082.1 - 0.00081 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 ETS78082.1 - 0.0054 16.2 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DUF915 PF06028.6 ETS78082.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BRE PF06113.7 ETS78082.1 - 0.21 10.5 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) MFS_1 PF07690.11 ETS78083.1 - 2.3e-34 118.6 48.1 1.8e-33 115.7 32.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78083.1 - 4.2e-12 45.3 17.2 4.2e-12 45.3 12.0 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 ETS78083.1 - 0.0012 17.4 16.1 0.0012 17.4 11.1 2.5 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like p450 PF00067.17 ETS78085.1 - 2.6e-53 181.1 0.0 3.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HECT PF00632.20 ETS78086.1 - 1.9e-69 234.2 0.0 2.7e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 ETS78087.1 - 1e-35 121.8 8.4 1.5e-29 102.1 1.0 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 ETS78087.1 - 1.6e-06 28.0 22.1 1.9e-05 24.6 0.6 4.4 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS78087.1 - 5e-05 23.3 0.7 5e-05 23.3 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 ETS78087.1 - 0.0085 16.3 7.8 0.23 11.8 0.4 4.1 3 1 1 4 4 4 2 C2H2-type zinc finger ZZ PF00569.12 ETS78087.1 - 0.085 12.4 2.0 4.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-C2H2 PF00096.21 ETS78087.1 - 0.086 13.2 15.6 3.2 8.2 0.2 4.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type p450 PF00067.17 ETS78088.1 - 5.1e-40 137.3 0.0 3.1e-39 134.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 ETS78089.1 - 3.9e-08 32.8 0.1 1.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS78089.1 - 0.00019 21.0 0.0 0.00065 19.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain VHS PF00790.14 ETS78090.1 - 9e-41 138.8 2.8 2.7e-40 137.2 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 ETS78090.1 - 7.8e-16 57.7 4.5 1.4e-15 56.9 3.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 ETS78090.1 - 8.4e-06 24.9 10.0 0.0085 15.5 0.5 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 ETS78090.1 - 0.0039 16.5 1.6 0.0039 16.5 1.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase UCH PF00443.24 ETS78091.1 - 1.2e-31 109.8 0.0 1.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS78091.1 - 4.9e-11 42.6 0.0 7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 ETS78091.1 - 0.00014 22.2 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 ETS78091.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain AMP-binding PF00501.23 ETS78092.1 - 1.1e-82 277.6 0.0 1.4e-82 277.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA_edit PF04073.10 ETS78092.1 - 0.0097 15.7 0.1 7.8 6.3 0.0 2.7 2 1 1 3 3 3 2 Aminoacyl-tRNA editing domain Cyclin_N PF00134.18 ETS78093.1 - 9.6e-14 51.0 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 ETS78093.1 - 1.7e-10 41.4 0.0 5.3e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin SRP40_C PF05022.7 ETS78094.1 - 5.3e-24 84.5 1.6 5.3e-24 84.5 1.1 2.5 2 0 0 2 2 2 1 SRP40, C-terminal domain Sclerostin PF05463.6 ETS78094.1 - 0.89 8.9 0.0 0.89 8.9 0.0 3.1 3 0 0 3 3 3 0 Sclerostin (SOST) RDD PF06271.7 ETS78095.1 - 0.0028 17.5 1.2 0.0028 17.5 0.8 2.1 2 1 0 2 2 2 1 RDD family DUF497 PF04365.8 ETS78095.1 - 0.0036 17.1 0.5 4.5 7.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF497) DUF3357 PF11837.3 ETS78095.1 - 0.14 12.0 7.1 3.8 7.4 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3357) DUF962 PF06127.6 ETS78095.1 - 6.5 6.7 6.6 2.9 7.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF962) PEX11 PF05648.9 ETS78096.1 - 2.1e-17 63.1 4.3 1.2e-08 34.4 0.1 3.9 2 2 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) His_Phos_1 PF00300.17 ETS78097.1 - 1.1e-19 71.0 0.1 5.3e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Serendipity_A PF05482.7 ETS78097.1 - 0.14 10.5 0.0 0.44 8.9 0.0 1.7 2 0 0 2 2 2 0 Serendipity locus alpha protein (SRY-A) Mitochondr_Som1 PF11093.3 ETS78097.1 - 0.15 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Coat_F PF07875.7 ETS78097.1 - 0.15 12.2 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Coat F domain PPP4R2 PF09184.6 ETS78099.1 - 0.088 12.3 10.5 0.092 12.2 7.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3295 PF11702.3 ETS78099.1 - 0.27 10.1 11.3 0.33 9.8 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RNA_pol_3_Rpc31 PF11705.3 ETS78099.1 - 1.4 8.7 33.9 1.7 8.5 23.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 ETS78099.1 - 4.6 7.0 18.4 4.1 7.1 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 ETS78099.1 - 4.7 6.3 9.4 5 6.2 6.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PTPA PF03095.10 ETS78100.1 - 1.7e-103 345.9 0.0 2e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CENP-F_leu_zip PF10473.4 ETS78102.1 - 0.00017 21.4 24.8 0.00017 21.4 17.2 12.0 1 1 9 11 11 11 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 ETS78102.1 - 0.025 14.7 0.1 0.025 14.7 0.1 11.9 2 1 13 15 15 15 0 Fibrinogen alpha/beta chain family Filament PF00038.16 ETS78102.1 - 0.054 12.9 212.6 0.35 10.3 26.3 9.2 1 1 6 7 7 7 0 Intermediate filament protein ArfGap PF01412.13 ETS78103.1 - 1.1e-40 138.0 0.7 1.7e-40 137.4 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.16 ETS78104.1 - 0.017 14.7 0.6 0.075 12.6 0.2 1.9 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.14 ETS78104.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 SNARE domain DUF500 PF04366.7 ETS78105.1 - 3.4e-44 149.3 0.1 5.6e-44 148.6 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 ETS78105.1 - 2.5e-12 45.9 0.1 9e-12 44.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 ETS78105.1 - 1.3e-10 40.5 0.0 2.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETS78105.1 - 1.6e-09 37.1 0.0 3.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 ETS78106.1 - 2.7e-70 237.1 0.0 3.5e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kinesin PF00225.18 ETS78106.1 - 5.2e-60 202.9 0.0 8.1e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF1996 PF09362.5 ETS78107.1 - 1.9e-63 214.2 1.3 2.5e-63 213.8 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.20 ETS78111.1 - 5.2e-05 23.2 0.1 5.7e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78111.1 - 0.00012 21.8 0.0 0.00013 21.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78111.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 KR domain CPT PF07931.7 ETS78113.1 - 0.1 12.2 0.5 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Myb_DNA-bind_2 PF08914.6 ETS78114.1 - 1.6e-32 111.0 1.1 1.2e-16 60.2 0.2 2.8 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.3 ETS78114.1 - 3.9e-19 68.3 0.3 3.3e-18 65.3 0.1 2.6 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 ETS78114.1 - 6.9e-13 49.0 0.3 2.5e-05 24.7 0.1 3.1 2 0 0 2 2 2 2 Rap1, DNA-binding ARID PF01388.16 ETS78114.1 - 3.2e-08 33.3 0.0 1.1e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myb_DNA-binding PF00249.26 ETS78114.1 - 0.0044 17.0 0.1 0.26 11.3 0.0 3.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS78114.1 - 0.0051 16.8 3.2 0.19 11.8 0.0 3.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain zf-DHHC PF01529.15 ETS78115.1 - 1.8e-35 121.8 5.3 2.8e-35 121.2 3.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase MMR_HSR1 PF01926.18 ETS78116.1 - 2.4e-15 56.5 0.0 6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS78116.1 - 2.8e-06 26.8 0.0 1.3e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETS78116.1 - 6e-05 22.2 0.0 0.00016 20.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 ETS78116.1 - 0.014 14.6 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 ETS78116.1 - 0.03 14.4 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 ETS78116.1 - 0.047 13.2 0.0 4.2 6.8 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 ETS78116.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 ETS78116.1 - 0.073 13.5 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 ETS78116.1 - 0.082 13.7 0.0 0.082 13.7 0.0 3.1 2 2 0 2 2 1 0 AAA domain AAA_29 PF13555.1 ETS78116.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 ETS78116.1 - 0.65 9.8 0.0 0.65 9.8 0.0 3.7 2 2 1 3 3 2 0 Dynamin family Complex1_LYR_2 PF13233.1 ETS78117.1 - 1.8e-19 70.1 0.3 2.1e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 ETS78117.1 - 0.00092 18.9 0.6 0.0013 18.4 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Hormone_3 PF00159.13 ETS78117.1 - 0.099 12.6 0.4 0.099 12.6 0.3 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide Complex1_LYR_1 PF13232.1 ETS78117.1 - 0.13 12.4 0.4 0.19 11.9 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like p450 PF00067.17 ETS78118.1 - 1.2e-69 235.0 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS78119.1 - 3.7e-27 95.1 0.0 1.8e-26 92.9 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 ETS78120.1 - 4.3e-51 173.6 0.1 9.6e-51 172.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS78120.1 - 1e-44 152.7 0.0 3e-44 151.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS78120.1 - 9.7e-22 76.7 0.0 1.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DXP_synthase_N PF13292.1 ETS78120.1 - 0.22 10.4 0.5 0.39 9.5 0.4 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Sugar_tr PF00083.19 ETS78121.1 - 2.3e-54 184.6 22.8 2.7e-54 184.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78121.1 - 8.2e-22 77.3 37.6 8.2e-22 77.3 26.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS78121.1 - 8e-08 31.0 23.3 0.00023 19.7 4.5 3.7 4 0 0 4 4 4 2 MFS/sugar transport protein DUF2207 PF09972.4 ETS78121.1 - 1.2 7.6 7.3 26 3.2 3.0 2.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FMN_red PF03358.10 ETS78123.1 - 3e-13 49.5 0.1 5.3e-13 48.7 0.1 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETS78123.1 - 4e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.11 ETS78124.1 - 1.9e-41 141.9 28.7 1.9e-41 141.9 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78124.1 - 2.2e-06 26.5 24.0 2.3e-05 23.1 16.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS78124.1 - 4.2e-05 21.9 1.8 7.5e-05 21.1 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aha1_N PF09229.6 ETS78125.1 - 9.1e-37 125.9 0.3 1.3e-36 125.4 0.2 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 ETS78125.1 - 1.1e-17 64.3 0.9 2.2e-17 63.3 0.6 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4448 PF14610.1 ETS78126.1 - 5e-25 88.0 0.0 7.8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3377 PF11857.3 ETS78126.1 - 0.015 14.9 0.2 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.1 ETS78126.1 - 0.036 13.7 0.1 0.036 13.7 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Dioxygenase_C PF00775.16 ETS78127.1 - 1.9e-12 46.8 0.9 1.2e-11 44.2 0.6 2.0 1 1 0 1 1 1 1 Dioxygenase Peptidase_M24 PF00557.19 ETS78128.1 - 3.6e-44 150.8 0.0 4.4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 ETS78128.1 - 0.0014 18.4 8.2 0.0014 18.4 5.7 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 ETS78128.1 - 0.38 10.4 3.4 0.86 9.3 2.3 1.7 1 0 0 1 1 1 0 HIT zinc finger Chitin_bind_3 PF03067.10 ETS78129.1 - 0.0011 19.2 1.7 0.0018 18.5 1.2 1.5 1 1 0 1 1 1 1 Chitin binding domain NfrA_C PF13283.1 ETS78129.1 - 0.097 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Glyco_hydro_43 PF04616.9 ETS78130.1 - 0.002 17.2 0.9 0.0033 16.5 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 ETS78130.1 - 0.0022 17.3 0.1 0.0056 16.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF2456 PF10445.4 ETS78131.1 - 6.2e-08 32.4 0.7 6.2e-08 32.4 0.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2456) IL28A PF15177.1 ETS78131.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin-28A p450 PF00067.17 ETS78132.1 - 3.8e-37 127.9 0.0 4.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS78133.1 - 1.6e-28 99.4 0.0 3.4e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glyco_tranf_2_5 PF13712.1 ETS78133.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family p450 PF00067.17 ETS78134.1 - 1.6e-24 86.2 0.0 2.6e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 ETS78135.1 - 2.5e-13 49.9 0.4 1.1e-12 47.8 0.3 2.1 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family ERG4_ERG24 PF01222.12 ETS78136.1 - 1.5e-85 287.3 7.2 1.8e-85 287.0 5.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETS78136.1 - 1.7e-05 24.2 0.5 5e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETS78136.1 - 0.0042 17.2 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS78136.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.8 3 0 0 3 3 3 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 ETS78137.1 - 3.5e-141 470.6 5.5 4.2e-141 470.3 3.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 ETS78137.1 - 0.00069 18.9 0.1 0.0016 17.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1035 PF06281.7 ETS78138.1 - 0.78 9.5 4.9 7.9 6.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1035) Pectinesterase PF01095.14 ETS78140.1 - 1.5e-47 161.6 8.6 1.9e-47 161.2 5.9 1.1 1 0 0 1 1 1 1 Pectinesterase Iso_dh PF00180.15 ETS78141.1 - 9.2e-87 291.2 0.0 1.1e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 ETS78142.1 - 1.2e-27 97.2 0.1 1.6e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS78142.1 - 6.3e-11 42.2 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS78142.1 - 2.6e-09 36.9 0.0 3.1e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS78142.1 - 0.058 11.8 0.0 0.091 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 ETS78142.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Thr_synth_N PF14821.1 ETS78142.1 - 0.088 12.8 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Threonine synthase N terminus Fungal_trans PF04082.13 ETS78144.1 - 8.2e-23 80.5 1.3 1.9e-22 79.3 0.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_2 PF00890.19 ETS78145.1 - 1.1e-94 317.7 0.1 1.2e-94 317.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS78145.1 - 7.8e-07 29.0 0.1 3.6e-06 26.8 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 ETS78145.1 - 7.9e-06 25.1 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS78145.1 - 3.7e-05 23.7 0.0 0.00034 20.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS78145.1 - 5.5e-05 22.2 0.8 0.00062 18.7 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS78145.1 - 0.00011 21.2 1.6 0.00013 20.9 0.0 1.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 ETS78145.1 - 0.00012 21.2 0.1 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 ETS78145.1 - 0.0008 18.5 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS78145.1 - 0.001 17.6 1.7 0.0029 16.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 ETS78145.1 - 0.0032 17.5 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS78145.1 - 0.0043 16.8 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS78145.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 ETS78145.1 - 0.052 13.9 0.1 2.8 8.4 0.0 3.4 4 1 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase TauD PF02668.11 ETS78146.1 - 1.5e-39 136.2 0.0 2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 ETS78147.1 - 2e-15 56.7 2.8 8.1e-14 51.4 2.0 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS78147.1 - 0.0095 15.9 0.0 0.097 12.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS78147.1 - 0.043 12.7 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.9 ETS78148.1 - 1.2e-65 221.4 0.5 1.4e-65 221.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_3 PF07859.8 ETS78150.1 - 5.5e-43 147.0 0.0 6.6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS78150.1 - 2.4e-06 27.5 0.3 4e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS78150.1 - 6.3e-06 26.0 0.0 8.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS78150.1 - 3.2e-05 23.2 0.0 0.00044 19.5 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 ETS78150.1 - 0.00014 21.2 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 ETS78150.1 - 0.0012 19.0 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.13 ETS78150.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 ETS78150.1 - 0.0025 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 ETS78150.1 - 0.005 15.3 0.0 0.0082 14.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 ETS78150.1 - 0.0065 15.8 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 ETS78150.1 - 0.0093 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 ETS78150.1 - 0.0098 15.1 0.1 0.029 13.6 0.1 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase BAAT_C PF08840.6 ETS78150.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 ETS78150.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 ETS78150.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Pyr_redox_2 PF07992.9 ETS78152.1 - 3.3e-14 53.2 0.0 1.8e-13 50.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS78152.1 - 6e-09 36.1 0.0 2.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS78152.1 - 0.00059 19.9 0.1 0.051 13.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS78152.1 - 0.013 14.4 0.0 0.063 12.1 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ADH_N PF08240.7 ETS78153.1 - 6.4e-27 93.4 0.4 1.6e-26 92.1 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS78153.1 - 1.1e-22 79.9 0.2 2.4e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS78153.1 - 0.0015 19.3 0.0 0.0036 18.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF4453 PF14627.1 ETS78153.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Cyto_heme_lyase PF01265.12 ETS78154.1 - 0.12 11.9 4.0 2.1 7.8 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c/c1 heme lyase MFS_1 PF07690.11 ETS78155.1 - 1.4e-34 119.4 35.6 1.4e-34 119.4 24.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78155.1 - 2.9e-15 55.8 32.1 3.3e-12 45.7 8.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter NDUFA12 PF05071.11 ETS78155.1 - 0.12 12.8 0.1 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3493 PF11998.3 ETS78155.1 - 0.49 10.3 2.9 5.5 6.9 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) CHORD PF04968.7 ETS78156.1 - 0.008 16.4 5.6 0.011 15.9 0.7 2.3 2 0 0 2 2 2 1 CHORD DUF3342 PF11822.3 ETS78156.1 - 0.016 14.4 0.3 0.019 14.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) zf-C2H2_6 PF13912.1 ETS78156.1 - 0.041 13.7 0.8 0.088 12.7 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger TFIIS_C PF01096.13 ETS78156.1 - 0.79 9.4 5.1 0.25 11.0 0.9 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) BTK PF00779.14 ETS78156.1 - 2.7 7.6 8.7 0.13 11.8 0.5 2.5 3 0 0 3 3 3 0 BTK motif Zn_clus PF00172.13 ETS78157.1 - 2.3e-10 40.2 11.4 4.7e-10 39.2 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS78157.1 - 1.6e-05 23.9 0.1 3.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase PF03211.8 ETS78158.1 - 1.4e-53 181.5 11.5 1.2e-44 152.2 5.9 2.3 1 1 1 2 2 2 2 Pectate lyase Pro_CA PF00484.14 ETS78159.1 - 2.5e-27 95.7 0.0 3.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF1100 PF06500.6 ETS78160.1 - 5e-12 45.1 0.0 6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 ETS78160.1 - 5.7e-10 39.1 0.0 9.9e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78160.1 - 1.1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS78160.1 - 9.8e-05 21.8 0.0 0.00055 19.4 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 ETS78160.1 - 0.00015 21.2 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 ETS78160.1 - 0.0032 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS78160.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal MIT PF04212.13 ETS78160.1 - 0.012 15.5 0.2 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Abhydrolase_1 PF00561.15 ETS78160.1 - 0.021 14.4 1.0 0.14 11.6 0.3 2.4 3 1 1 4 4 4 0 alpha/beta hydrolase fold DLH PF01738.13 ETS78160.1 - 0.048 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyco_transf_25 PF01755.12 ETS78161.1 - 3.1e-05 23.6 0.0 0.00064 19.4 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short_C2 PF13561.1 ETS78162.1 - 3.2e-31 108.9 0.1 3.7e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS78162.1 - 3.4e-27 95.3 2.4 4.3e-27 95.0 1.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS78162.1 - 6.9e-09 35.6 0.7 1.1e-08 34.9 0.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78162.1 - 0.0073 15.7 0.1 0.01 15.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS78162.1 - 0.014 15.1 0.3 0.038 13.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3716 PF12511.3 ETS78163.1 - 5.6e-06 25.8 6.2 9.6e-06 25.1 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF747 PF05346.6 ETS78164.1 - 1.8e-131 438.1 2.0 2.4e-131 437.7 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Herpes_LMP1 PF05297.6 ETS78164.1 - 0.05 12.5 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Cutinase PF01083.17 ETS78165.1 - 5.8e-47 159.7 0.8 7.2e-47 159.4 0.6 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 ETS78165.1 - 0.00068 19.4 0.3 0.001 18.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 ETS78165.1 - 0.00092 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PE-PPE PF08237.6 ETS78165.1 - 0.0014 18.0 0.5 0.033 13.6 0.1 2.1 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_2 PF02230.11 ETS78165.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 ETS78165.1 - 0.011 15.5 0.1 0.034 14.0 0.1 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.6 ETS78165.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 ETS78165.1 - 0.048 13.2 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MF_alpha_N PF05436.6 ETS78165.1 - 0.094 12.4 0.3 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Thioesterase PF00975.15 ETS78165.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 ETS78165.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 ETS78166.1 - 4.2e-09 35.9 0.1 0.002 17.3 0.1 3.4 2 2 3 5 5 5 2 Protein kinase domain APH PF01636.18 ETS78166.1 - 0.0048 16.6 0.6 0.0088 15.7 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 ETS78166.1 - 0.11 11.5 0.0 4.9 6.1 0.0 3.0 2 1 0 2 2 2 0 Protein tyrosine kinase Pox_D5 PF03288.11 ETS78166.1 - 0.12 12.6 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Poxvirus D5 protein-like DUF4066 PF13278.1 ETS78167.1 - 3.2e-30 104.6 0.0 3.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS78167.1 - 1.1e-12 47.5 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 ETS78167.1 - 0.0088 15.5 0.0 0.015 14.7 0.0 1.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Acyl_transf_3 PF01757.17 ETS78168.1 - 1.7e-30 106.0 37.2 2.2e-30 105.6 25.8 1.1 1 0 0 1 1 1 1 Acyltransferase family DoxX_3 PF13781.1 ETS78170.1 - 2.5 8.5 16.5 0.48 10.8 1.3 3.3 3 0 0 3 3 3 0 DoxX-like family ABC_tran PF00005.22 ETS78171.1 - 1e-45 155.4 0.0 4.2e-23 82.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS78171.1 - 3.2e-29 102.2 39.4 6.8e-24 84.7 13.5 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS78171.1 - 1.1e-10 41.9 0.5 0.0021 18.0 0.2 4.3 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 ETS78171.1 - 2.9e-09 36.4 5.5 0.0018 17.5 0.8 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 ETS78171.1 - 1.2e-06 28.0 2.3 0.025 14.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS78171.1 - 1.9e-06 28.0 1.8 0.084 13.0 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS78171.1 - 4.9e-06 26.6 2.4 0.0078 16.2 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 ETS78171.1 - 1.7e-05 25.2 3.4 0.0063 16.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS78171.1 - 2.8e-05 24.9 0.2 0.51 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 ETS78171.1 - 5.6e-05 23.4 0.1 0.36 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS78171.1 - 0.00011 21.2 0.7 0.35 9.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.24 ETS78171.1 - 0.00013 22.2 2.4 0.0048 17.1 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 ETS78171.1 - 0.00015 22.2 0.1 0.38 11.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 ETS78171.1 - 0.00017 21.0 0.5 0.041 13.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETS78171.1 - 0.00018 20.7 0.0 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 ETS78171.1 - 0.0011 18.6 0.7 0.72 9.5 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETS78171.1 - 0.0016 18.3 0.0 0.49 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS78171.1 - 0.002 17.6 1.6 0.15 11.5 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETS78171.1 - 0.0045 16.9 1.4 0.64 10.0 0.6 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS78171.1 - 0.0068 15.8 1.2 0.48 9.7 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_30 PF13604.1 ETS78171.1 - 0.0071 15.9 0.6 9.6 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 ETS78171.1 - 0.0072 15.8 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.4 ETS78171.1 - 0.0091 14.6 0.4 2.9 6.4 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 ETS78171.1 - 0.012 15.0 1.8 3.4 7.0 0.1 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 ETS78171.1 - 0.017 15.0 0.5 1.9 8.4 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 ETS78171.1 - 0.021 14.4 2.2 3.2 7.3 0.1 2.9 3 0 0 3 3 2 0 NACHT domain GTP_EFTU PF00009.22 ETS78171.1 - 0.027 13.8 0.2 7.9 5.8 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 ETS78171.1 - 0.031 14.1 0.1 12 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 ETS78171.1 - 0.038 13.7 3.5 0.075 12.8 0.2 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 ETS78171.1 - 0.039 13.7 0.2 8.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.17 ETS78171.1 - 0.039 12.7 0.3 13 4.5 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_19 PF13245.1 ETS78171.1 - 0.051 13.3 2.2 0.51 10.1 0.2 2.9 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 ETS78171.1 - 0.066 12.8 0.1 7.3 6.2 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase RNA_helicase PF00910.17 ETS78171.1 - 0.074 13.2 0.1 24 5.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 ETS78171.1 - 0.087 12.5 0.1 13 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 ETS78171.1 - 0.09 11.8 0.4 3.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Phage_glycop_gL PF11108.3 ETS78171.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Viral glycoprotein L NTPase_1 PF03266.10 ETS78171.1 - 0.2 11.3 3.3 2.7 7.6 0.1 2.7 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.1 ETS78171.1 - 0.36 10.7 2.3 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain Tht1 PF04163.7 ETS78172.1 - 2.6e-05 22.8 1.1 6.6e-05 21.5 0.7 1.7 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Lipoprotein_7 PF01540.11 ETS78172.1 - 0.046 12.7 1.8 0.8 8.7 0.0 2.2 1 1 1 2 2 2 0 Adhesin lipoprotein NPV_P10 PF05531.7 ETS78172.1 - 0.18 12.0 3.6 2.9 8.1 0.0 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Carbpep_Y_N PF05388.6 ETS78172.1 - 0.69 10.0 3.7 28 4.8 0.0 3.5 1 1 2 3 3 3 0 Carboxypeptidase Y pro-peptide DUF3450 PF11932.3 ETS78172.1 - 2.7 7.1 8.4 1.9 7.6 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ribosomal_L6 PF00347.18 ETS78173.1 - 3.7e-22 78.6 0.0 9.6e-12 45.2 0.0 3.3 3 1 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 ETS78174.1 - 2.1e-54 184.6 3.0 5.3e-54 183.3 2.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 ETS78175.1 - 6e-27 94.0 0.2 4.5e-21 75.0 0.2 2.7 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 ETS78175.1 - 4.2e-26 90.6 1.1 8.3e-25 86.4 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 ETS78175.1 - 0.00083 19.7 0.4 0.044 14.2 0.2 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain E1-E2_ATPase PF00122.15 ETS78176.1 - 1.4e-49 168.2 1.2 1.6e-48 164.7 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETS78176.1 - 2.2e-37 129.5 0.6 5.1e-37 128.3 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS78176.1 - 3.4e-21 76.2 0.0 7.1e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 ETS78176.1 - 1e-12 47.9 0.0 1.3e-10 41.2 0.0 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 ETS78176.1 - 5.8e-05 22.7 0.3 0.00042 19.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4342 PF14242.1 ETS78176.1 - 0.26 11.0 3.0 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Ribonuclease_T2 PF00445.13 ETS78178.1 - 2.5e-42 144.6 4.4 3.6e-42 144.1 3.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family HEAT_2 PF13646.1 ETS78179.1 - 3.9e-20 71.9 14.9 5e-06 26.6 0.1 9.1 4 3 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 ETS78179.1 - 6.2e-18 64.7 17.6 7.5e-06 26.2 0.3 12.2 11 2 3 14 14 14 3 HEAT-like repeat HEAT PF02985.17 ETS78179.1 - 4.9e-14 51.0 10.0 0.0097 15.9 0.1 10.1 12 0 0 12 12 11 3 HEAT repeat Adaptin_N PF01602.15 ETS78179.1 - 2.7e-11 42.5 3.3 0.0001 20.7 0.0 4.6 3 2 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 ETS78179.1 - 6.6e-11 42.4 1.1 0.11 12.8 0.0 7.1 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 ETS78179.1 - 1.6e-08 34.3 0.0 0.085 12.5 0.0 3.8 3 0 0 3 3 3 3 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 ETS78179.1 - 3.5e-07 29.8 1.3 0.008 15.5 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal IBN_N PF03810.14 ETS78179.1 - 6.2e-07 29.2 1.3 3.6e-06 26.8 0.0 2.9 3 0 0 3 3 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 ETS78179.1 - 4.3e-06 26.7 6.3 1.3 8.8 0.2 5.7 4 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 ETS78179.1 - 0.0018 18.0 9.4 19 5.2 0.0 7.3 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 ETS78179.1 - 0.0073 15.0 0.0 0.0073 15.0 0.0 3.9 3 2 1 5 5 5 1 RNAPII transcription regulator C-terminal UNC45-central PF11701.3 ETS78179.1 - 0.0087 15.7 4.9 0.16 11.5 0.3 3.7 2 1 0 3 3 3 1 Myosin-binding striated muscle assembly central YukD PF08817.5 ETS78179.1 - 0.021 15.3 0.4 5.4 7.6 0.0 3.3 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD DUF2454 PF10521.4 ETS78179.1 - 0.12 11.3 1.4 5.4 5.9 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2454) V-ATPase_H_C PF11698.3 ETS78179.1 - 1.6 8.6 6.1 23 4.9 0.0 4.9 6 1 1 7 7 6 0 V-ATPase subunit H zf-U1 PF06220.7 ETS78180.1 - 4e-07 29.4 0.4 6.4e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 ETS78180.1 - 0.045 13.2 4.8 0.063 12.7 3.2 1.5 1 1 0 1 1 1 0 Coiled coil protein 84 WSK PF03832.8 ETS78180.1 - 9.5 5.6 9.4 0.58 9.5 1.8 2.5 2 0 0 2 2 2 0 WSK motif PIR PF00399.14 ETS78181.1 - 1.3e-08 33.9 23.1 9.5e-06 24.7 2.1 4.5 3 0 0 3 3 3 3 Yeast PIR protein repeat Pec_lyase_C PF00544.14 ETS78183.1 - 1.7e-44 151.6 9.7 2.9e-44 150.9 6.7 1.4 1 0 0 1 1 1 1 Pectate lyase Phage_attach PF05354.6 ETS78183.1 - 0.055 13.0 1.1 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Phage Head-Tail Attachment A_deaminase PF00962.17 ETS78185.1 - 2.7e-42 144.8 0.0 4.9e-42 144.0 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase ARL6IP6 PF15062.1 ETS78185.1 - 0.035 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Pkinase PF00069.20 ETS78187.1 - 4.1e-72 242.4 0.0 5.2e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78187.1 - 4e-33 114.5 0.0 7e-33 113.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS78187.1 - 0.0018 17.3 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS78187.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS78187.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.1 ETS78188.1 - 2.5e-32 112.2 0.0 4.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETS78188.1 - 0.076 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Lipase_GDSL PF00657.17 ETS78189.1 - 1.4e-07 31.5 0.4 2e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ceramidase_alk PF04734.8 ETS78190.1 - 6.6e-284 942.9 0.3 7.5e-284 942.8 0.2 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF1604 PF07713.8 ETS78191.1 - 4.1e-38 129.0 2.8 1.2e-37 127.5 2.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 ETS78191.1 - 2.8e-07 30.1 1.9 1.7e-06 27.6 0.5 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 ETS78191.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 3.2 4 0 0 4 4 4 1 DExH-box splicing factor binding site Pkinase PF00069.20 ETS78192.1 - 7.2e-75 251.4 0.0 1.1e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78192.1 - 3.7e-39 134.3 0.0 1.6e-38 132.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 ETS78192.1 - 5.8e-18 64.0 0.1 9.5e-18 63.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 ETS78192.1 - 5.7e-05 22.2 0.1 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETS78192.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS78192.1 - 0.0058 16.3 0.0 0.049 13.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETS78192.1 - 0.026 13.8 0.1 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 ETS78192.1 - 0.052 12.7 0.1 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 ETS78192.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETS78192.1 - 0.22 11.1 0.1 0.47 9.9 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2014 PF09427.5 ETS78193.1 - 1.3e-104 348.9 2.0 2e-104 348.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 ETS78193.1 - 2.4e-17 62.3 0.7 5e-17 61.3 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CIA30 PF08547.7 ETS78194.1 - 1.9e-39 135.0 0.0 2.5e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 ETS78195.1 - 4.4e-05 23.3 6.4 7.3e-05 22.6 4.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS78195.1 - 0.0047 16.7 9.0 0.0074 16.0 6.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Na_H_Exchanger PF00999.16 ETS78196.1 - 2.9e-68 230.1 51.1 4.5e-68 229.5 35.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1241 PF06840.6 ETS78196.1 - 0.12 11.6 0.2 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Utp14 PF04615.8 ETS78198.1 - 2.1e-171 571.7 66.2 2.1e-171 571.7 45.9 2.2 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 ETS78199.1 - 2.7e-17 62.4 0.2 4.2e-17 61.7 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Smr PF01713.16 ETS78200.1 - 3.3e-07 30.4 1.3 4.6e-07 29.9 0.2 1.8 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 ETS78200.1 - 0.0021 18.0 3.9 0.0021 18.0 2.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) PAP1 PF08601.5 ETS78201.1 - 3.9e-60 204.3 10.2 3.9e-60 204.3 7.1 2.3 1 1 1 2 2 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 ETS78201.1 - 5.9e-10 38.9 11.2 1.2e-09 38.0 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 ETS78201.1 - 0.00011 21.8 5.2 0.00017 21.1 3.6 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_2 PF07716.10 ETS78201.1 - 0.00015 21.4 14.1 0.00063 19.5 9.8 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 ETS78201.1 - 0.012 16.1 1.4 0.012 16.1 1.0 2.1 3 0 0 3 3 2 0 Adenovirus hexon-associated protein (IX) SPT16 PF08644.6 ETS78201.1 - 0.026 14.3 2.7 0.054 13.3 1.9 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Cluap1 PF10234.4 ETS78201.1 - 0.027 13.6 8.4 0.046 12.9 5.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMF_DNA_bd PF12329.3 ETS78201.1 - 0.031 14.0 10.2 0.062 13.1 7.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 ETS78201.1 - 0.035 14.3 10.3 0.072 13.3 7.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF904 PF06005.7 ETS78201.1 - 0.061 13.6 7.3 0.14 12.4 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 ETS78201.1 - 0.067 13.5 4.2 0.17 12.2 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GAS PF13851.1 ETS78201.1 - 0.085 12.0 9.3 0.16 11.1 6.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETS78201.1 - 0.092 12.3 6.8 0.077 12.5 3.5 1.6 2 0 0 2 2 2 0 IncA protein FlaC_arch PF05377.6 ETS78201.1 - 0.13 12.1 1.6 0.24 11.3 1.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF812 PF05667.6 ETS78201.1 - 0.19 10.2 7.6 0.27 9.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.6 ETS78201.1 - 0.26 8.7 1.0 0.37 8.2 0.7 1.1 1 0 0 1 1 1 0 Prominin Sigma70_ner PF04546.8 ETS78201.1 - 0.4 10.2 11.5 1.1 8.8 6.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region APG6 PF04111.7 ETS78201.1 - 0.4 9.6 7.3 0.61 9.0 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL6 PF01763.11 ETS78201.1 - 0.5 8.4 5.0 0.72 7.9 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CENP-H PF05837.7 ETS78201.1 - 0.76 9.9 6.7 1.7 8.8 4.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.10 ETS78201.1 - 0.91 9.0 3.8 1.7 8.1 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 ETS78201.1 - 2.4 5.8 3.1 3.3 5.4 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BSD PF03909.12 ETS78202.1 - 5.2e-17 61.3 0.0 1.2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 BSD domain Presenilin PF01080.12 ETS78202.1 - 6.9 5.3 10.9 6.4 5.4 0.5 2.2 2 0 0 2 2 2 0 Presenilin WGG PF10273.4 ETS78203.1 - 5e-29 100.2 0.5 9.7e-29 99.2 0.3 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 ETS78203.1 - 0.017 15.1 3.3 0.037 14.0 0.1 2.4 1 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) TFIIF_alpha PF05793.7 ETS78203.1 - 0.12 10.6 11.8 0.14 10.5 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Trypan_PARP PF05887.6 ETS78203.1 - 1.9 8.2 6.9 1.9 8.2 3.4 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CENP-B_dimeris PF09026.5 ETS78203.1 - 3.4 7.9 10.0 8.3 6.7 6.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_3 PF07859.8 ETS78204.1 - 2.2e-40 138.5 0.0 3.1e-31 108.6 0.1 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS78204.1 - 1.7e-14 53.2 0.0 9.9e-14 50.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 ETS78204.1 - 0.00019 20.2 2.7 0.069 11.8 0.0 2.8 3 0 0 3 3 3 2 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS78204.1 - 0.00074 19.2 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78204.1 - 0.006 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyridox_oxidase PF01243.15 ETS78205.1 - 1.9e-06 27.7 0.0 0.00022 21.1 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 ETS78205.1 - 0.00097 19.6 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CTP_transf_2 PF01467.21 ETS78206.1 - 6.5e-23 81.5 0.0 8.3e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase U1snRNP70_N PF12220.3 ETS78207.1 - 0.097 13.0 4.9 0.077 13.3 1.0 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Patched PF02460.13 ETS78208.1 - 1.4e-77 261.4 12.9 4e-50 170.6 0.2 2.9 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 ETS78208.1 - 5.5e-51 172.0 6.7 5.5e-51 172.0 4.6 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 ETS78208.1 - 7.2e-06 25.7 1.8 1.3e-05 24.8 1.2 1.3 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.10 ETS78208.1 - 7.5e-06 24.8 7.6 7.5e-06 24.8 5.3 2.8 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.14 ETS78208.1 - 0.16 9.2 17.7 0.028 11.8 7.3 2.2 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family HET PF06985.6 ETS78210.1 - 2.4e-11 43.9 0.1 6.5e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) QH-AmDH_gamma PF08992.6 ETS78210.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Glyco_hydro_7 PF00840.15 ETS78211.1 - 8.5e-209 693.3 26.2 1e-208 693.0 18.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FIST_C PF10442.4 ETS78212.1 - 0.0079 16.1 0.9 0.34 10.8 0.1 2.5 1 1 2 3 3 3 1 FIST C domain DUF2580 PF10824.3 ETS78212.1 - 0.26 11.6 4.9 0.075 13.3 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) DUF2514 PF10721.4 ETS78212.1 - 2.3 7.9 5.0 0.43 10.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) PAS_9 PF13426.1 ETS78215.1 - 3.3e-16 59.5 0.0 4.6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 ETS78215.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 ETS78215.1 - 0.052 13.3 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.5 ETS78215.1 - 0.092 12.7 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold zf-RING_4 PF14570.1 ETS78217.1 - 9.1e-20 69.9 13.3 1.7e-19 69.1 9.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 ETS78217.1 - 4e-09 35.9 0.0 2.8e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS78217.1 - 3.1e-06 27.0 0.0 1.7e-05 24.6 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 ETS78217.1 - 4.7e-06 26.1 6.5 8.3e-06 25.3 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 ETS78217.1 - 7.4e-06 25.3 2.3 2.1e-05 23.8 1.6 1.7 1 0 0 1 1 1 1 Rtf2 RING-finger RRM_5 PF13893.1 ETS78217.1 - 7.1e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 ETS78217.1 - 0.0033 17.1 5.1 0.0058 16.3 3.5 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Pol_alpha_B_N PF08418.5 ETS78217.1 - 0.004 16.7 0.5 0.004 16.7 0.4 3.3 4 1 0 4 4 3 1 DNA polymerase alpha subunit B N-terminal Nup35_RRM_2 PF14605.1 ETS78217.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 ETS78217.1 - 0.015 14.5 0.1 0.083 12.2 0.0 2.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated zf-UDP PF14569.1 ETS78217.1 - 0.11 12.3 4.4 0.27 11.0 3.0 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 ETS78217.1 - 0.2 11.3 11.7 0.39 10.4 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS78217.1 - 1.3 9.0 11.6 2.5 8.1 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 ETS78217.1 - 9.3 5.8 11.0 1.9 8.1 4.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Complex1_30kDa PF00329.14 ETS78218.1 - 7.8e-35 119.2 0.0 1.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit E1_dh PF00676.15 ETS78219.1 - 1.2e-88 296.7 0.0 1.4e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 ETS78219.1 - 0.00024 20.7 0.3 0.003 17.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 ETS78219.1 - 0.048 12.5 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase SGS PF05002.10 ETS78219.1 - 0.09 12.5 1.5 0.65 9.7 0.3 2.5 2 1 0 2 2 2 0 SGS domain Arylsulfotran_2 PF14269.1 ETS78220.1 - 1.6e-46 158.8 1.2 1.6e-46 158.8 0.8 1.7 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS78220.1 - 5.4e-18 64.7 1.3 7.2e-18 64.3 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PAS PF00989.19 ETS78220.1 - 0.12 12.1 0.0 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 PAS fold MFS_1 PF07690.11 ETS78221.1 - 7.2e-18 64.4 23.2 7.2e-18 64.4 16.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily VMA21 PF09446.5 ETS78221.1 - 0.0093 15.8 0.5 0.031 14.2 0.3 1.9 1 0 0 1 1 1 1 VMA21-like domain Sulfotransfer_3 PF13469.1 ETS78222.1 - 9.3e-06 26.6 0.7 1.5e-05 25.9 0.5 1.4 1 0 0 1 1 1 1 Sulfotransferase family Abhydrolase_6 PF12697.2 ETS78223.1 - 2e-23 83.4 0.7 5.8e-23 81.9 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS78223.1 - 0.00066 18.2 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 ETS78223.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family HECT PF00632.20 ETS78224.1 - 2.4e-78 263.4 0.0 4.4e-78 262.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 ETS78224.1 - 0.0006 19.5 0.4 1.1 9.1 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 ETS78224.1 - 0.00097 19.0 2.8 0.16 12.1 0.0 4.5 4 1 1 5 5 5 1 HEAT repeat Clr5 PF14420.1 ETS78224.1 - 0.036 13.9 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain HEAT_EZ PF13513.1 ETS78224.1 - 0.042 14.3 0.2 0.9 10.1 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat RRN3 PF05327.6 ETS78224.1 - 3.8 5.5 16.1 0.22 9.5 5.8 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Fungal_trans PF04082.13 ETS78225.1 - 2.8e-13 49.3 1.8 2.8e-13 49.3 1.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pectate_lyase_3 PF12708.2 ETS78226.1 - 7.2e-86 287.9 22.4 7.2e-69 232.3 6.3 3.3 2 1 0 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 ETS78226.1 - 6.7e-05 22.2 5.1 0.01 15.2 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PhyH PF05721.8 ETS78227.1 - 5.6e-09 36.3 0.3 3.8e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MARVEL PF01284.18 ETS78228.1 - 0.034 13.9 1.8 0.068 12.9 1.2 1.6 1 1 0 1 1 1 0 Membrane-associating domain Polysacc_synt_C PF14667.1 ETS78228.1 - 5.1 6.8 9.9 0.44 10.3 2.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Suf PF05843.9 ETS78228.1 - 6.2 6.4 7.6 11 5.7 5.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) F-box PF00646.28 ETS78229.1 - 0.019 14.6 0.5 0.098 12.3 0.0 2.2 2 0 0 2 2 2 0 F-box domain Methyltransf_16 PF10294.4 ETS78230.1 - 1e-11 44.5 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS78230.1 - 0.00059 20.3 0.0 0.00081 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS78230.1 - 0.0068 15.5 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 ETS78230.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Surp PF01805.15 ETS78232.1 - 5.3e-18 64.4 0.0 1.3e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Surp module DAO PF01266.19 ETS78233.1 - 2e-47 161.8 1.6 2.4e-47 161.5 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS78233.1 - 2.7e-06 27.2 0.6 0.057 13.1 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS78233.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS78233.1 - 0.0002 21.4 0.2 0.042 13.9 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS78233.1 - 0.00082 18.3 2.6 0.014 14.3 1.8 2.1 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS78233.1 - 0.0066 15.3 0.0 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETS78233.1 - 0.0079 15.2 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS78233.1 - 0.0093 15.8 0.0 2.5 7.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS78233.1 - 0.014 14.3 0.0 0.38 9.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 ETS78233.1 - 0.076 12.1 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family TBP PF00352.16 ETS78234.1 - 3.3e-70 231.4 0.1 5.3e-35 118.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 ETS78234.1 - 0.00017 21.6 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 ETS78234.1 - 0.01 16.1 0.9 0.013 15.8 0.7 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) ETF_QO PF05187.8 ETS78236.1 - 1.8e-46 156.6 0.1 3e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 ETS78236.1 - 6.4e-08 32.5 0.0 1.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS78236.1 - 6.5e-08 31.8 0.0 0.0001 21.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 ETS78236.1 - 1.8e-05 23.9 0.0 0.0013 17.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 ETS78236.1 - 7.1e-05 22.0 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS78236.1 - 0.00011 21.2 0.2 0.0027 16.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS78236.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS78236.1 - 0.00019 20.0 0.4 0.00027 19.5 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 ETS78236.1 - 0.00035 19.3 0.0 0.13 10.8 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 ETS78236.1 - 0.00078 18.5 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS78236.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS78236.1 - 0.0019 17.9 0.3 0.005 16.6 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 ETS78236.1 - 0.0037 17.5 1.3 0.011 16.0 0.9 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 ETS78236.1 - 0.0091 16.3 0.0 4.8 7.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS78236.1 - 0.017 14.0 0.2 0.024 13.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETS78236.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn_clus PF00172.13 ETS78237.1 - 1.5e-07 31.1 7.6 1.5e-07 31.1 5.3 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 ETS78237.1 - 0.00035 20.7 2.6 0.001 19.3 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS78237.1 - 0.004 17.3 1.6 0.004 17.3 1.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 ETS78237.1 - 0.043 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ham1p_like PF01725.11 ETS78238.1 - 8.8e-48 162.1 0.0 9.8e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M2 PF01401.13 ETS78239.1 - 0.016 13.4 0.1 0.023 12.9 0.1 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme CopD PF05425.8 ETS78239.1 - 2 8.6 10.0 0.37 11.0 3.3 2.1 2 0 0 2 2 2 0 Copper resistance protein D An_peroxidase PF03098.10 ETS78240.1 - 2.9e-122 408.7 0.0 3.3e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase LURAP PF14854.1 ETS78241.1 - 0.02 14.5 0.5 0.088 12.5 0.0 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein Glyco_hydro_75 PF07335.6 ETS78242.1 - 1e-35 122.9 0.0 7.8e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 Fungal chitosanase of glycosyl hydrolase group 75 Peptidase_S28 PF05577.7 ETS78243.1 - 1.4e-46 158.9 0.2 2.1e-46 158.4 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 zf-primase PF09329.6 ETS78244.1 - 3e-18 65.1 0.8 5.2e-18 64.3 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger IRK PF01007.15 ETS78244.1 - 0.052 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel tRNA_anti-codon PF01336.20 ETS78244.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3619 PF12279.3 ETS78244.1 - 0.14 12.2 4.9 0.46 10.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) RNase_H2-Ydr279 PF09468.5 ETS78245.1 - 8.6e-89 297.7 2.0 1.2e-88 297.2 1.4 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3727 PF12527.3 ETS78245.1 - 0.035 14.2 0.1 0.035 14.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) DUF3340 PF11818.3 ETS78245.1 - 0.049 13.5 5.3 0.15 11.9 3.6 1.8 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DASH_Duo1 PF08651.5 ETS78246.1 - 7.2e-30 102.3 1.1 1e-29 101.8 0.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3340 PF11818.3 ETS78246.1 - 0.0004 20.3 4.1 0.00062 19.7 2.8 1.2 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) DUF4407 PF14362.1 ETS78246.1 - 0.031 13.2 7.7 0.039 12.9 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PVL_ORF50 PF07768.6 ETS78246.1 - 0.079 12.9 6.0 0.16 11.9 4.2 1.5 1 0 0 1 1 1 0 PVL ORF-50-like family DUF1682 PF07946.9 ETS78246.1 - 0.3 9.8 6.1 0.43 9.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.20 ETS78248.1 - 7e-16 58.1 0.0 1.7e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78248.1 - 4.9e-09 35.6 0.0 3.5e-08 32.8 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Aminotran_4 PF01063.14 ETS78249.1 - 1.5e-30 106.4 0.0 2.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ESSS PF10183.4 ETS78250.1 - 9.2e-28 96.7 0.2 1.1e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Beta-lactamase PF00144.19 ETS78251.1 - 8.9e-43 146.5 5.5 1.3e-42 145.9 3.8 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 ETS78251.1 - 4.1e-09 36.1 0.0 6.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) FMN_bind_2 PF04299.7 ETS78251.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain SIR2 PF02146.12 ETS78252.1 - 3.2e-57 193.1 0.0 5.4e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 ETS78252.1 - 2.5e-05 23.8 0.0 7.4e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 ETS78252.1 - 0.0046 16.7 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 ETS78253.1 - 2.6e-54 183.6 1.1 2.6e-54 183.6 0.8 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS78253.1 - 3.2e-42 144.1 7.4 3.2e-42 144.1 5.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS78253.1 - 9.7e-29 101.3 0.0 3.9e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS78253.1 - 1.8e-18 66.2 0.0 3.6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS78253.1 - 5.5e-16 59.3 0.0 9.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS78253.1 - 2.5e-06 26.8 0.0 8.6e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS78253.1 - 7.9e-06 25.6 0.5 4e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 ETS78253.1 - 0.028 13.1 3.4 0.044 12.5 1.5 1.8 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family TF_Zn_Ribbon PF08271.7 ETS78253.1 - 0.26 10.6 0.0 0.86 8.9 0.0 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding TTL PF03133.10 ETS78255.1 - 3.6e-58 196.8 0.0 5.7e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 ETS78255.1 - 2.8e-42 144.2 0.0 4.4e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.1 ETS78255.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 ETS78255.1 - 0.0013 18.9 0.1 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ATPgrasp_YheCD PF14398.1 ETS78255.1 - 0.002 16.9 0.0 0.0096 14.7 0.0 2.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 ETS78255.1 - 0.049 13.3 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Glyco_transf_28 PF03033.15 ETS78255.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain FCH PF00611.18 ETS78256.1 - 2e-22 79.1 0.4 7.5e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 ETS78256.1 - 9.5e-13 47.3 0.0 1.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS78256.1 - 1.9e-10 40.1 0.0 3.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS78256.1 - 2.6e-10 39.6 0.0 6.7e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Seipin PF06775.9 ETS78257.1 - 3.2e-51 173.6 1.2 6.2e-51 172.7 0.6 1.6 2 0 0 2 2 2 1 Putative adipose-regulatory protein (Seipin) HET PF06985.6 ETS78259.1 - 1.2e-13 51.4 2.4 1.2e-13 51.3 0.2 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Dispanin PF04505.7 ETS78259.1 - 0.18 11.3 0.2 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Bac_luciferase PF00296.15 ETS78260.1 - 8.9e-65 218.8 0.3 1.1e-64 218.4 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TOH_N PF12549.3 ETS78260.1 - 0.058 12.9 2.4 0.77 9.4 1.1 2.6 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal AAA_16 PF13191.1 ETS78261.1 - 4.1e-06 26.9 0.5 1.2e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 ETS78261.1 - 0.00027 20.5 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 ETS78261.1 - 0.0005 20.2 0.2 0.0053 16.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 ETS78261.1 - 0.00074 18.4 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.8 ETS78261.1 - 0.00085 18.9 0.0 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 ETS78261.1 - 0.0019 17.5 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.7 ETS78261.1 - 0.01 15.5 1.4 0.043 13.4 1.0 2.0 1 1 0 1 1 1 0 NACHT domain IATP PF04568.7 ETS78262.1 - 2.7 8.0 4.7 6.6 6.8 3.3 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF3210 PF11489.3 ETS78263.1 - 2.4e-200 667.8 66.5 2.4e-200 667.8 46.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 ETS78264.1 - 2.8e-35 120.6 14.1 3.3e-35 120.4 9.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 ETS78264.1 - 0.53 9.8 7.3 0.95 9.0 5.0 1.4 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit NTF2 PF02136.15 ETS78265.1 - 1.9e-31 108.8 1.0 2.1e-31 108.7 0.7 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3089 PF11288.3 ETS78265.1 - 0.051 12.7 0.5 0.061 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF4440 PF14534.1 ETS78265.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) FUSC_2 PF13515.1 ETS78266.1 - 5.7e-17 61.8 32.9 2.1e-14 53.5 8.1 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 ETS78266.1 - 1.1e-09 37.6 5.7 6.4e-09 35.1 1.3 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 ETS78266.1 - 1.3e-07 30.6 3.0 1.3e-07 30.6 2.1 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF2421 PF10334.4 ETS78266.1 - 4.5e-06 26.4 0.5 2.3e-05 24.1 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2421) FUSC PF04632.7 ETS78266.1 - 0.006 15.0 27.5 0.02 13.3 1.3 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family Wzy_C PF04932.10 ETS78266.1 - 0.15 11.7 11.6 0.5 10.1 0.3 3.5 4 0 0 4 4 4 0 O-Antigen ligase Fapy_DNA_glyco PF01149.19 ETS78268.1 - 1.2e-28 99.7 0.1 2.3e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 ETS78268.1 - 3.6e-19 68.3 0.0 6.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 ETS78268.1 - 4.3e-05 22.2 0.1 0.019 13.5 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) Pribosyl_synth PF14572.1 ETS78269.1 - 2.2e-41 141.6 0.3 8e-35 120.2 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 ETS78269.1 - 5.5e-32 109.9 0.0 2.3e-31 107.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 ETS78269.1 - 3.8e-11 42.8 0.2 8.6e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain dsrm PF00035.20 ETS78270.1 - 3e-05 24.5 0.0 4.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 ETS78270.1 - 0.00079 19.6 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 NMO PF03060.10 ETS78271.1 - 5.3e-65 219.7 0.2 1.1e-64 218.6 0.2 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETS78271.1 - 8.8e-11 41.2 0.0 0.00012 21.1 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 ETS78271.1 - 0.0016 17.3 0.3 0.0034 16.2 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS78271.1 - 0.0068 15.3 0.3 0.014 14.2 0.2 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 ETS78271.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Cupin_2 PF07883.6 ETS78272.1 - 2.2e-15 55.8 0.2 8.3e-15 54.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.3 ETS78272.1 - 1.6e-05 24.7 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_1 PF00190.17 ETS78272.1 - 0.00035 20.0 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 ETS78272.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 ETS78272.1 - 0.0024 17.2 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) DUF1498 PF07385.7 ETS78272.1 - 0.034 13.2 0.0 0.086 11.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) Cupin_6 PF12852.2 ETS78272.1 - 0.052 13.1 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Ndc80_HEC PF03801.8 ETS78275.1 - 7.2e-64 214.0 0.4 7.2e-64 214.0 0.3 1.8 2 0 0 2 2 2 1 HEC/Ndc80p family FliJ PF02050.11 ETS78275.1 - 0.007 16.4 5.0 0.007 16.4 3.5 4.5 3 1 1 4 4 4 2 Flagellar FliJ protein DUF1664 PF07889.7 ETS78275.1 - 0.0075 16.0 0.4 0.0075 16.0 0.3 4.8 3 2 1 5 5 5 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 ETS78275.1 - 0.011 14.3 38.6 0.066 11.8 8.7 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 ETS78275.1 - 0.18 11.9 0.2 0.18 11.9 0.1 5.4 3 2 3 6 6 6 0 Central kinetochore-associated ATG16 PF08614.6 ETS78275.1 - 0.21 11.3 41.9 11 5.7 13.8 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FliD_C PF07195.7 ETS78275.1 - 0.21 10.8 18.4 1.7 7.8 1.7 3.9 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Strep_SA_rep PF06696.6 ETS78275.1 - 0.27 11.0 12.6 0.2 11.4 0.2 4.3 4 0 0 4 4 4 0 Streptococcal surface antigen repeat TMP_2 PF06791.8 ETS78275.1 - 0.37 10.3 4.1 1.7 8.2 0.8 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein Filament PF00038.16 ETS78275.1 - 0.91 8.9 51.1 2.3 7.5 17.1 3.2 2 1 0 2 2 2 0 Intermediate filament protein DUF3450 PF11932.3 ETS78275.1 - 2.2 7.4 35.5 0.045 13.0 7.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 ETS78275.1 - 7.2 6.6 35.4 0.032 14.1 2.9 5.6 4 2 0 5 5 5 0 bZIP transcription factor V_ATPase_I PF01496.14 ETS78275.1 - 7.7 4.2 38.0 0.25 9.1 8.5 2.5 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family ESCRT-II PF05871.7 ETS78276.1 - 7.5e-48 161.9 0.2 1.1e-47 161.4 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit PTCB-BRCT PF12738.2 ETS78277.1 - 3.6e-30 103.6 0.1 4.8e-18 64.7 0.1 4.7 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 ETS78277.1 - 3.2e-28 97.7 0.6 1.3e-06 28.4 0.0 6.1 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.11 ETS78278.1 - 5.9e-36 123.8 26.3 5.9e-36 123.8 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3754 PF12576.3 ETS78278.1 - 0.13 11.9 1.6 0.35 10.5 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) BMFP PF04380.8 ETS78279.1 - 7.6 6.7 10.5 2.8 8.1 2.1 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity Glyco_hydro_16 PF00722.16 ETS78280.1 - 3.2e-46 156.9 4.7 3.2e-46 156.9 3.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UCH PF00443.24 ETS78281.1 - 5.3e-07 29.0 0.2 2.2e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS78281.1 - 7.4e-06 25.6 0.0 3.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.6 ETS78281.1 - 0.0027 17.1 6.5 0.0027 17.1 4.5 4.5 4 1 1 5 5 5 1 Mitochondrial fission regulator Nucleoplasmin PF03066.10 ETS78281.1 - 0.31 10.5 15.6 0.0091 15.5 5.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF791 PF05631.9 ETS78282.1 - 3e-32 111.6 5.3 4.2e-32 111.2 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETS78282.1 - 1.3e-16 60.2 24.2 2e-16 59.6 16.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MraY_sig1 PF10555.4 ETS78282.1 - 0.025 13.8 1.0 5.2 6.6 0.0 2.9 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 F-box-like PF12937.2 ETS78284.1 - 0.0014 18.2 1.4 0.0056 16.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like AAA PF00004.24 ETS78286.1 - 2.5e-20 73.0 0.0 7.6e-20 71.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS78286.1 - 5.9e-05 23.8 0.1 0.00041 21.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 ETS78286.1 - 6.8e-05 22.4 1.2 0.0018 17.7 0.8 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 ETS78286.1 - 0.00027 20.9 2.5 0.0032 17.4 0.0 3.5 3 2 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 ETS78286.1 - 0.0003 20.4 0.7 0.00068 19.3 0.5 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 ETS78286.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS78286.1 - 0.0017 18.4 0.4 0.029 14.5 0.1 2.8 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS78286.1 - 0.0098 15.7 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 ETS78286.1 - 0.01 16.1 0.1 0.049 13.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS78286.1 - 0.016 15.4 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 ETS78286.1 - 0.018 14.6 0.0 0.058 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS78286.1 - 0.052 13.5 1.6 0.48 10.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 ETS78286.1 - 0.064 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 ETS78286.1 - 0.073 12.1 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS78286.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TCO89 PF10452.4 ETS78287.1 - 4.5e-07 29.1 20.9 0.0008 18.4 0.0 3.4 3 0 0 3 3 3 2 TORC1 subunit TCO89 DUF422 PF04240.7 ETS78288.1 - 0.029 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF422) Glyco_tranf_2_3 PF13641.1 ETS78288.1 - 0.068 12.9 0.2 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Fungal_trans PF04082.13 ETS78289.1 - 2.4e-26 92.1 0.6 5.2e-26 91.0 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78289.1 - 2.5e-05 24.0 5.2 4.5e-05 23.2 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dna2 PF08696.6 ETS78291.1 - 6.5e-72 241.2 0.9 6.5e-72 241.2 0.6 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 ETS78291.1 - 4.4e-53 179.6 0.0 8.7e-53 178.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS78291.1 - 1.1e-40 139.6 0.3 2.6e-20 73.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 ETS78291.1 - 6.6e-13 48.6 0.0 2.7e-12 46.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 ETS78291.1 - 4.7e-11 42.2 0.1 1.2e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 ETS78291.1 - 4.5e-10 39.6 0.5 7.2e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 ETS78291.1 - 3.9e-09 36.2 0.0 7.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 ETS78291.1 - 5.6e-07 29.3 0.8 0.28 10.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 ETS78291.1 - 8.5e-05 21.9 0.0 0.00023 20.6 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 ETS78291.1 - 0.00011 21.9 0.0 0.0003 20.4 0.0 1.8 1 0 0 1 1 1 1 Helicase SRP54 PF00448.17 ETS78291.1 - 0.00043 19.7 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 ETS78291.1 - 0.00049 19.1 0.0 0.0025 16.8 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase MobB PF03205.9 ETS78291.1 - 0.0016 18.1 0.1 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF911 PF06023.7 ETS78291.1 - 0.0021 17.3 0.1 0.0052 16.0 0.1 1.6 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) AAA_16 PF13191.1 ETS78291.1 - 0.0027 17.7 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 ETS78291.1 - 0.0051 16.2 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 ETS78291.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETS78291.1 - 0.018 14.0 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 ETS78291.1 - 0.028 14.5 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 ETS78291.1 - 0.044 13.6 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 RuvB_N PF05496.7 ETS78291.1 - 0.044 12.8 0.1 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 ETS78291.1 - 0.1 12.3 0.2 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 NTPase SGL PF08450.7 ETS78292.1 - 1.8e-23 83.1 0.6 3.7e-23 82.1 0.4 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETS78292.1 - 0.00017 21.5 0.0 0.0012 18.8 0.0 2.3 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 ETS78292.1 - 0.00026 20.9 0.0 0.0029 17.5 0.0 2.6 1 1 1 2 2 2 1 Arylesterase NHL PF01436.16 ETS78292.1 - 0.014 15.2 2.9 0.13 12.2 0.0 2.8 3 0 0 3 3 3 0 NHL repeat His_Phos_1 PF00300.17 ETS78293.1 - 8.3e-13 48.7 0.0 1.7e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Not1 PF04054.10 ETS78294.1 - 5e-82 275.7 0.0 1.1e-81 274.6 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 ETS78294.1 - 5.4e-47 159.1 4.9 1.6e-46 157.6 3.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Tautomerase_3 PF14832.1 ETS78295.1 - 2.6e-43 147.3 0.2 5e-43 146.3 0.1 1.4 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme UPF0029 PF01205.14 ETS78296.1 - 1.3e-23 82.7 0.0 2.9e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 LRR_4 PF12799.2 ETS78297.1 - 5.2e-36 121.7 34.7 3.4e-07 29.7 0.4 10.1 5 2 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS78297.1 - 1.5e-31 107.9 30.5 1.9e-09 37.1 1.9 9.1 4 2 7 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 ETS78297.1 - 1.6e-15 54.7 29.4 0.89 9.8 0.2 15.4 17 1 0 17 17 17 4 Leucine Rich Repeat LRR_7 PF13504.1 ETS78297.1 - 2.2e-09 35.9 36.8 2 8.9 0.2 12.7 14 0 0 14 14 14 5 Leucine rich repeat LRR_6 PF13516.1 ETS78297.1 - 2.9e-08 32.9 23.2 0.23 11.6 0.2 9.9 10 2 1 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 ETS78297.1 - 0.0029 17.1 8.3 0.047 13.2 0.6 4.0 3 2 1 4 4 4 1 Leucine-rich repeat Phlebovirus_NSM PF07246.6 ETS78298.1 - 0.22 10.6 3.7 0.36 9.9 2.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M BAR_2 PF10455.4 ETS78298.1 - 0.28 10.0 10.5 0.8 8.5 7.3 1.7 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mnd1 PF03962.10 ETS78298.1 - 2.4 7.7 9.1 5 6.7 6.3 1.5 1 0 0 1 1 1 0 Mnd1 family Thiolase_N PF00108.18 ETS78299.1 - 1.7e-70 237.0 1.1 2.4e-70 236.5 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS78299.1 - 1.1e-40 137.9 0.2 2.3e-40 136.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Phage_tube PF04985.9 ETS78299.1 - 0.42 10.0 2.5 0.59 9.5 0.7 1.9 1 1 1 2 2 2 0 Phage tail tube protein FII GATase PF00117.23 ETS78301.1 - 9.5e-09 34.9 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF2798 PF11391.3 ETS78302.1 - 0.013 15.2 2.1 0.038 13.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) ABC2_membrane_5 PF13346.1 ETS78302.1 - 0.12 11.5 2.4 0.18 11.0 1.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Med3 PF11593.3 ETS78302.1 - 0.19 10.9 4.8 0.2 10.8 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 ETS78302.1 - 1.9 6.2 8.0 2.3 5.9 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 ETS78302.1 - 3.8 5.1 7.5 5 4.7 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3446 PF11928.3 ETS78302.1 - 8.9 6.5 9.1 4.9 7.4 4.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MmgE_PrpD PF03972.9 ETS78304.1 - 2.5e-69 233.5 0.1 3.1e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Kelch_4 PF13418.1 ETS78305.1 - 1.5e-26 91.9 1.9 2.7e-07 30.2 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS78305.1 - 1e-21 76.4 12.5 1.6e-07 31.2 0.0 6.4 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_1 PF01344.20 ETS78305.1 - 2.2e-16 59.1 0.1 0.00077 18.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETS78305.1 - 1.1e-15 57.0 0.4 0.0013 18.8 0.0 4.5 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 ETS78305.1 - 7.8e-14 50.8 0.8 0.00066 19.3 0.0 4.4 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 ETS78305.1 - 8.6e-14 51.1 0.1 0.0052 16.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Meth_synt_2 PF01717.13 ETS78306.1 - 1e-10 41.1 0.0 7.4e-09 35.0 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS78306.1 - 0.0094 15.2 0.0 0.061 12.5 0.0 2.1 3 1 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Epimerase PF01370.16 ETS78307.1 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Death PF00531.17 ETS78307.1 - 0.066 12.9 0.5 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Death domain MFS_1 PF07690.11 ETS78308.1 - 2e-35 122.1 20.1 2e-35 122.1 13.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Arm PF00514.18 ETS78309.1 - 3.5e-05 23.4 1.9 0.7 9.8 0.0 5.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat KAP PF05804.7 ETS78309.1 - 0.027 12.4 0.0 0.25 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) HEAT PF02985.17 ETS78309.1 - 0.056 13.5 0.3 1.9 8.7 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Proteasom_PSMB PF10508.4 ETS78309.1 - 0.18 10.0 1.4 0.33 9.1 0.4 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Ribosomal_L13e PF01294.13 ETS78310.1 - 2.1e-66 222.8 4.1 2.9e-66 222.3 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e CAP59_mtransfer PF11735.3 ETS78311.1 - 1.9e-50 171.3 0.0 2.6e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ank_2 PF12796.2 ETS78312.1 - 6.5e-24 84.0 0.0 8.6e-08 32.4 0.0 5.6 3 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS78312.1 - 3.3e-15 56.1 0.7 9.2e-06 26.0 0.0 7.9 7 3 3 10 10 10 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78312.1 - 8.5e-14 50.2 1.3 0.06 13.6 0.0 8.7 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.25 ETS78312.1 - 2.4e-09 36.5 9.7 0.13 12.1 0.0 9.3 11 1 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.1 ETS78312.1 - 2.2e-06 27.6 0.2 0.72 10.2 0.0 6.0 6 1 2 8 8 8 2 Ankyrin repeats (many copies) F-box-like PF12937.2 ETS78313.1 - 5.8e-05 22.7 1.4 5.8e-05 22.7 1.0 2.1 2 0 0 2 2 2 1 F-box-like Ank PF00023.25 ETS78313.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat F-box-like_2 PF13013.1 ETS78313.1 - 0.033 13.8 1.5 0.18 11.5 0.9 2.0 2 0 0 2 2 2 0 F-box-like domain Ank_2 PF12796.2 ETS78313.1 - 0.034 14.4 0.1 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS78313.1 - 0.052 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78313.1 - 0.064 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat AA_permease_2 PF13520.1 ETS78315.1 - 8.7e-60 202.4 51.2 1.1e-59 202.1 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS78315.1 - 2.7e-28 98.5 45.8 3.6e-28 98.1 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease OPT PF03169.10 ETS78316.1 - 9.5e-180 599.0 46.5 1.1e-179 598.9 32.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hira PF07569.6 ETS78317.1 - 3.7e-86 287.8 0.1 1.1e-85 286.3 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 ETS78317.1 - 3e-44 147.3 20.6 3.7e-08 32.9 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 ETS78317.1 - 2e-12 46.2 1.2 5.4e-12 44.9 0.8 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 ETS78317.1 - 0.00018 21.1 0.2 37 4.1 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Atrophin-1 PF03154.10 ETS78317.1 - 0.0013 16.9 0.8 0.0026 15.9 0.5 1.4 1 0 0 1 1 1 1 Atrophin-1 family IKI3 PF04762.7 ETS78317.1 - 0.14 9.9 0.2 0.69 7.6 0.0 2.1 3 0 0 3 3 3 0 IKI3 family RR_TM4-6 PF06459.7 ETS78317.1 - 3.2 7.5 8.3 5.1 6.9 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_15 PF01793.11 ETS78318.1 - 1.2e-113 379.4 5.0 1.6e-113 379.0 3.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Lac_bphage_repr PF06543.7 ETS78318.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Sugar_tr PF00083.19 ETS78319.1 - 8.5e-80 268.5 23.4 1.1e-79 268.1 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78319.1 - 1.5e-26 92.9 30.5 4.8e-26 91.3 21.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS78319.1 - 6.4e-08 31.2 2.4 1.1e-07 30.5 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS78319.1 - 0.11 10.5 3.7 0.19 9.8 2.6 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3477 PF11963.3 ETS78319.1 - 0.22 10.4 0.5 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3477) Clr5 PF14420.1 ETS78320.1 - 3e-12 46.2 0.2 5.8e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain CBM_1 PF00734.13 ETS78323.1 - 3.9e-13 48.8 15.7 1e-12 47.4 10.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 ETS78323.1 - 7.7e-07 28.0 46.4 0.39 10.7 0.4 10.2 11 0 0 11 11 11 7 BNR/Asp-box repeat COX14 PF14880.1 ETS78324.1 - 4e-16 58.3 0.9 4e-16 58.3 0.6 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1515 PF07439.6 ETS78324.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Thioredoxin_8 PF13905.1 ETS78326.1 - 0.51 10.4 6.1 6.4 6.9 0.0 4.7 5 1 1 6 6 6 0 Thioredoxin-like CAP59_mtransfer PF11735.3 ETS78327.1 - 9.7e-66 221.4 0.0 1.5e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 GFA PF04828.9 ETS78328.1 - 3e-19 68.7 1.4 1.9e-08 34.0 0.1 3.0 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 ETS78328.1 - 3 7.4 17.0 0.53 9.8 0.6 3.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain SPATIAL PF15256.1 ETS78329.1 - 0.36 10.8 3.6 0.44 10.5 2.5 1.1 1 0 0 1 1 1 0 SPATIAL DUF4316 PF14195.1 ETS78329.1 - 3.4 7.7 7.1 8.9 6.4 4.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4316) gag_pre-integrs PF13976.1 ETS78330.1 - 0.0019 17.8 0.3 0.0034 17.0 0.2 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain DEAD PF00270.24 ETS78332.1 - 1.6e-41 141.6 0.0 3.9e-41 140.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78332.1 - 2.5e-22 78.5 0.0 5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS78332.1 - 0.00094 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS78332.1 - 0.0092 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS78332.1 - 0.14 12.3 0.2 0.69 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsJ PF01728.14 ETS78333.1 - 4.6e-61 205.9 0.0 6.2e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Vps16_C PF04840.7 ETS78335.1 - 0.057 12.3 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Fungal_trans_2 PF11951.3 ETS78336.1 - 1.8e-20 72.8 8.0 2.3e-20 72.5 5.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 ETS78337.1 - 6.4e-19 68.2 0.5 6.1e-18 64.9 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS78337.1 - 2.6e-12 46.3 0.1 2.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS78337.1 - 7.7e-07 27.9 0.0 0.012 14.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 ETS78337.1 - 9.4e-06 25.4 0.4 7.9e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS78337.1 - 1.2e-05 25.4 0.1 4.1e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS78337.1 - 6e-05 23.0 0.0 0.00036 20.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS78337.1 - 9.2e-05 21.6 0.7 0.0082 15.2 0.1 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS78337.1 - 9.3e-05 22.7 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS78337.1 - 0.00013 20.9 0.0 0.043 12.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.9 ETS78337.1 - 0.0073 14.9 0.1 1.6 7.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS78337.1 - 0.008 15.1 0.2 0.082 11.8 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS78337.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 ETS78337.1 - 0.025 14.0 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 ETS78337.1 - 0.031 13.1 0.0 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 ETS78337.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 ETS78337.1 - 0.072 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 ETS78337.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Abhydrolase_5 PF12695.2 ETS78338.1 - 3.2e-05 23.7 0.1 4.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78338.1 - 3.2e-05 23.9 0.6 3.9e-05 23.6 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 ETS78338.1 - 5.3e-05 21.6 0.1 0.0017 16.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 ETS78338.1 - 0.00033 19.6 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS78338.1 - 0.012 14.4 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1664 PF07889.7 ETS78339.1 - 0.55 10.0 6.1 0.14 11.9 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 ETS78339.1 - 2.4 8.3 6.2 57 3.9 3.9 2.6 1 1 1 2 2 2 0 Syntaxin DUF2461 PF09365.5 ETS78340.1 - 3.4e-70 235.7 0.1 4.8e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) AT_hook PF02178.14 ETS78340.1 - 3.1 7.7 24.0 3.4 7.6 3.3 3.6 3 0 0 3 3 3 0 AT hook motif MFS_1 PF07690.11 ETS78342.1 - 2.6e-23 82.3 45.7 3.3e-17 62.2 14.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78342.1 - 2.8e-05 22.9 10.4 2.8e-05 22.9 7.2 3.4 3 1 1 4 4 4 3 Sugar (and other) transporter Ndc1_Nup PF09531.5 ETS78342.1 - 2.7 6.3 5.2 0.62 8.4 0.6 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2433 PF10360.4 ETS78345.1 - 3.5e-54 182.6 0.0 5.4e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 ETS78345.1 - 0.00049 20.4 1.2 0.0023 18.2 0.8 2.1 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 ETS78345.1 - 0.0039 17.0 0.0 0.0089 15.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETS78345.1 - 0.0049 16.2 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ubie_methyltran PF01209.13 ETS78346.1 - 8.8e-77 257.3 0.0 1.1e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ETS78346.1 - 3.1e-14 53.2 0.0 1.8e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78346.1 - 9.7e-14 51.2 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS78346.1 - 4.9e-12 46.1 0.0 8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS78346.1 - 3.9e-11 43.2 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS78346.1 - 4.8e-09 36.1 0.0 7.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78346.1 - 6.1e-07 30.0 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS78346.1 - 1.2e-05 25.3 0.0 3.6e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS78346.1 - 0.11 11.8 0.0 0.35 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 ETS78346.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Chromo_shadow PF01393.14 ETS78347.1 - 1.1e-15 57.1 0.1 4.8e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 ETS78347.1 - 2.7e-12 46.1 1.0 2.7e-12 46.1 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-Di19 PF05605.7 ETS78348.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 ETS78348.1 - 0.07 12.3 0.5 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 ETS78348.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 ETS78348.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PHY PF00360.15 ETS78349.1 - 3.9e-27 94.5 0.0 8.8e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 ETS78349.1 - 3.3e-20 71.8 0.3 6e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS78349.1 - 1.8e-16 60.0 0.1 1.8e-15 56.8 0.0 2.5 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 ETS78349.1 - 1e-14 54.9 0.0 4e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 ETS78349.1 - 5.7e-12 45.4 0.4 1.3e-11 44.2 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 ETS78349.1 - 1.6e-08 34.9 0.0 5.7e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 PAS fold E1-E2_ATPase PF00122.15 ETS78350.1 - 3.5e-69 232.3 0.1 3.5e-69 232.3 0.1 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 ETS78350.1 - 2.4e-25 90.2 0.0 7e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS78350.1 - 2.1e-14 54.1 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS78350.1 - 3.1e-09 36.1 0.0 8.8e-09 34.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS78350.1 - 0.00052 19.6 0.4 0.0013 18.4 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 7TM_GPCR_Srsx PF10320.4 ETS78350.1 - 0.00062 18.9 0.5 1.1 8.3 0.1 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx GNVR PF13807.1 ETS78350.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ApbA PF02558.11 ETS78351.1 - 3.4e-30 104.4 0.0 5.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 ETS78351.1 - 2.5e-27 95.3 0.0 6e-27 94.1 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DIOX_N PF14226.1 ETS78352.1 - 2.3e-29 102.2 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS78352.1 - 3.3e-23 81.8 0.0 1e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF21 PF01595.15 ETS78353.1 - 1.4e-32 112.5 0.0 2.6e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 ETS78353.1 - 3.2e-05 23.6 0.8 0.042 13.6 0.0 3.2 3 0 0 3 3 3 2 CBS domain T4_Gp59_C PF08994.5 ETS78353.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Rrn6 PF10214.4 ETS78353.1 - 5.8 4.8 7.4 8.1 4.4 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Lactonase PF10282.4 ETS78354.1 - 6.1e-18 65.0 0.0 7.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS78354.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Zip PF02535.17 ETS78355.1 - 1.5e-42 145.7 5.7 5.9e-26 91.2 3.1 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter Cation_efflux PF01545.16 ETS78356.1 - 1.7e-37 129.0 7.7 2e-37 128.8 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF423 PF04241.10 ETS78356.1 - 2.1 8.2 5.1 0.96 9.4 1.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF423) tRNA-synt_2 PF00152.15 ETS78358.1 - 4.5e-89 298.5 0.1 6.2e-89 298.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS78358.1 - 9.4e-13 47.8 0.1 1.7e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ETS78358.1 - 2.8e-07 29.9 0.0 0.0034 16.6 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 ETS78358.1 - 0.019 14.5 0.0 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) COX15-CtaA PF02628.10 ETS78359.1 - 1.3e-96 323.0 9.6 1.6e-96 322.7 6.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein HET PF06985.6 ETS78361.1 - 8.3e-19 68.1 9.8 1.3e-16 61.0 4.5 3.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Cupin_8 PF13621.1 ETS78362.1 - 1.5e-24 86.8 0.0 1.8e-24 86.5 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETS78362.1 - 8e-05 22.0 0.0 0.00037 19.8 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 ETS78362.1 - 0.0025 18.0 0.0 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 ETS78362.1 - 0.0062 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Cupin domain CK_II_beta PF01214.13 ETS78363.1 - 4.6e-76 254.4 0.0 1.6e-75 252.6 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Myc_N PF01056.13 ETS78363.1 - 0.26 10.4 6.9 0.059 12.5 2.3 1.6 2 0 0 2 2 2 0 Myc amino-terminal region RRN3 PF05327.6 ETS78363.1 - 0.53 8.3 2.1 0.77 7.8 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 ETS78363.1 - 8.4 5.8 13.6 0.67 9.4 4.8 2.0 2 0 0 2 2 2 0 Nucleoplasmin Aldedh PF00171.17 ETS78364.1 - 5.2e-145 483.3 0.0 6.4e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 ETS78365.1 - 5.5e-15 54.9 0.0 8.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78365.1 - 6.2e-09 35.6 10.4 1.1e-08 34.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dala_Dala_lig_C PF07478.8 ETS78366.1 - 1.7e-11 43.9 0.0 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 ETS78366.1 - 4.2e-11 42.9 0.0 8.9e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS78366.1 - 3.9e-06 25.8 0.0 5.6e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 ETS78366.1 - 0.0033 16.7 0.0 0.02 14.1 0.0 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 ETS78366.1 - 0.0058 16.2 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 ETS78366.1 - 0.055 13.3 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 ETS78366.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dabb PF07876.7 ETS78367.1 - 9.9e-13 48.3 0.1 1.5e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Amidohydro_2 PF04909.9 ETS78368.1 - 3.7e-21 75.8 0.0 4.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 ETS78369.1 - 3.5e-34 118.0 36.0 3.5e-34 118.0 24.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SUKH-4 PF14435.1 ETS78369.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein HET PF06985.6 ETS78370.1 - 1.2e-33 116.1 12.7 4.9e-31 107.7 2.8 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF362 PF04015.7 ETS78370.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) BNR PF02012.15 ETS78371.1 - 0.088 12.6 0.4 0.088 12.6 0.3 3.1 3 0 0 3 3 3 0 BNR/Asp-box repeat NmrA PF05368.8 ETS78372.1 - 2.7e-15 56.2 0.0 3.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS78372.1 - 2e-11 44.2 0.8 8.7e-11 42.1 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS78372.1 - 1e-10 41.4 0.2 9.9e-08 31.7 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS78372.1 - 2.6e-05 24.2 1.3 4.5e-05 23.4 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 ETS78372.1 - 0.0002 21.6 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 ETS78372.1 - 0.00025 20.7 0.7 0.00053 19.7 0.3 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 ETS78372.1 - 0.00059 18.8 0.7 0.0015 17.5 0.2 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS78372.1 - 0.00072 18.5 0.3 0.0025 16.7 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 ETS78372.1 - 0.005 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 ETS78372.1 - 0.0053 16.8 0.1 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 ETS78372.1 - 0.012 15.5 1.7 0.25 11.2 0.1 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 ETS78372.1 - 0.02 14.8 0.3 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 ETS78372.1 - 0.035 13.8 0.1 0.096 12.4 0.1 1.8 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CbiJ PF02571.9 ETS78372.1 - 0.037 13.3 0.2 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_4 PF07993.7 ETS78372.1 - 0.065 12.1 0.1 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.18 ETS78372.1 - 0.078 12.7 0.7 0.099 12.4 0.0 1.6 2 0 0 2 2 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 ETS78372.1 - 0.092 11.6 0.2 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 ETS78372.1 - 0.13 11.4 0.1 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hyd_65N_2 PF14498.1 ETS78374.1 - 3.6e-37 128.2 0.1 5.6e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 ETS78374.1 - 0.0008 18.1 0.1 0.0014 17.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain MFS_1 PF07690.11 ETS78375.1 - 1.3e-16 60.2 47.7 1.8e-15 56.5 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78375.1 - 6.9e-07 28.1 9.6 6.9e-07 28.1 6.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4149 PF13664.1 ETS78375.1 - 0.015 15.3 0.6 0.015 15.3 0.4 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) Aldo_ket_red PF00248.16 ETS78376.1 - 3.6e-49 167.0 0.0 6.5e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 ETS78376.1 - 8.5e-17 60.8 0.1 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 ETS78377.1 - 7.5e-31 107.1 0.0 1.8e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ldh_2 PF02615.9 ETS78380.1 - 3.2e-99 331.8 0.0 3.6e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Methyltransf_6 PF03737.10 ETS78381.1 - 6.1e-28 97.6 0.0 8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Amidohydro_2 PF04909.9 ETS78382.1 - 3.4e-13 49.8 0.5 4.2e-13 49.4 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase F_bP_aldolase PF01116.15 ETS78383.1 - 6.7e-90 301.0 0.0 7.5e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II An_peroxidase PF03098.10 ETS78384.1 - 2e-94 316.8 0.0 2.4e-73 247.3 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 ETS78384.1 - 0.0091 14.5 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 ETS78386.1 - 2e-22 79.6 2.3 3e-22 79.1 1.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 ETS78386.1 - 2.9e-06 27.1 18.2 0.0027 17.4 1.0 2.2 1 1 1 2 2 2 2 Right handed beta helix region DUF1996 PF09362.5 ETS78387.1 - 3.1e-89 298.6 3.2 4.2e-89 298.2 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Senescence PF06911.7 ETS78388.1 - 0.00043 20.0 2.2 0.00047 19.9 1.5 1.1 1 0 0 1 1 1 1 Senescence-associated protein dCMP_cyt_deam_1 PF00383.17 ETS78389.1 - 6.5e-09 35.3 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region IL34 PF15036.1 ETS78389.1 - 0.097 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Interleukin 34 Glyco_hydro_76 PF03663.9 ETS78390.1 - 4.3e-109 365.3 16.1 5.5e-109 364.9 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tfb2 PF03849.9 ETS78393.1 - 2.2e-129 431.3 0.0 2.6e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 ETS78393.1 - 1.8e-07 30.9 0.1 9.1e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.5 ETS78393.1 - 0.045 13.1 0.6 0.39 10.1 0.0 2.8 3 0 0 3 3 3 0 Anti-repressor SinI DUF1275 PF06912.6 ETS78394.1 - 4.7e-40 137.0 13.3 5.9e-40 136.6 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PGG PF13962.1 ETS78394.1 - 0.049 13.2 3.2 0.066 12.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF202 PF02656.10 ETS78394.1 - 0.27 11.4 5.7 2.6 8.3 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 ETS78395.1 - 1.7e-32 112.5 26.4 1.7e-32 112.5 18.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 ETS78396.1 - 8.3e-87 291.3 3.8 9.6e-87 291.1 2.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 ETS78396.1 - 4.9e-05 21.7 0.6 8.4e-05 21.0 0.3 1.4 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 ETS78396.1 - 0.0016 17.8 9.2 0.15 11.3 1.2 2.8 1 1 2 3 3 3 2 Glycosyl hydrolase family 76 LANC_like PF05147.8 ETS78396.1 - 0.021 13.3 0.1 8.4 4.8 0.0 3.6 4 0 0 4 4 4 0 Lanthionine synthetase C-like protein SSF PF00474.12 ETS78397.1 - 2.9e-19 69.0 28.8 4.2e-19 68.4 20.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Anoctamin PF04547.7 ETS78398.1 - 2.3e-103 346.3 4.2 2.9e-103 345.9 2.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pkinase PF00069.20 ETS78399.1 - 8.9e-55 185.6 0.0 1.4e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78399.1 - 5.8e-29 100.9 0.0 1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS78399.1 - 2.4e-06 26.7 0.1 0.021 13.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETS78399.1 - 0.0018 17.3 0.1 0.0056 15.7 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 ETS78399.1 - 0.12 11.1 0.4 0.19 10.5 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RRM_1 PF00076.17 ETS78400.1 - 8.2e-16 57.3 0.0 1.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS78400.1 - 1.4e-12 47.3 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS78400.1 - 9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS78400.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF3233 PF11557.3 ETS78400.1 - 0.21 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) Fasciclin PF02469.17 ETS78402.1 - 3.6e-33 114.3 0.0 6.3e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.16 ETS78403.1 - 3.8e-19 68.6 1.5 7.4e-19 67.7 0.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 ETS78403.1 - 0.039 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Glyco_trans_2_3 PF13632.1 ETS78404.1 - 2.8e-46 157.6 7.5 2.8e-46 157.6 5.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS78404.1 - 2.6e-06 27.4 0.0 6.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS78404.1 - 7.7e-06 25.6 0.0 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS78404.1 - 0.0015 17.8 0.0 0.0036 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 KAR PF15222.1 ETS78405.1 - 0.00032 20.7 0.1 0.00072 19.5 0.1 1.6 1 1 0 1 1 1 1 Kidney androgen-regulated bZIP_1 PF00170.16 ETS78405.1 - 0.0043 16.9 4.6 0.0088 15.9 3.0 1.6 1 1 0 1 1 1 1 bZIP transcription factor DUF4139 PF13598.1 ETS78405.1 - 0.42 9.8 3.4 0.3 10.3 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) bZIP_2 PF07716.10 ETS78405.1 - 7.3 6.4 11.0 1.4 8.8 3.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper SBF PF01758.11 ETS78406.1 - 2.7e-47 160.6 9.8 2.7e-47 160.6 6.8 1.8 2 1 0 2 2 2 1 Sodium Bile acid symporter family Aldo_ket_red PF00248.16 ETS78408.1 - 6.8e-58 195.7 0.0 7.8e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OGFr_N PF04664.8 ETS78409.1 - 1.5e-21 76.7 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region TcdA_TcdB PF12919.2 ETS78410.1 - 0.056 11.9 1.3 0.062 11.7 0.9 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PAN_4 PF14295.1 ETS78411.1 - 2.1e-05 24.1 1.2 4.9e-05 22.9 0.8 1.7 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 ETS78411.1 - 0.024 14.2 0.3 0.024 14.2 0.2 1.8 2 0 0 2 2 2 0 PAN-like domain E_Pc_C PF06752.7 ETS78411.1 - 0.037 13.5 11.6 0.054 12.9 8.0 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF3427 PF11907.3 ETS78412.1 - 0.049 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) WSC PF01822.14 ETS78413.1 - 1.9e-69 229.5 61.4 5.8e-20 70.9 7.6 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 ETS78413.1 - 3e-25 88.7 0.0 1.6e-23 83.0 0.0 3.2 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 ETS78413.1 - 9.3e-25 86.5 0.3 2.1e-24 85.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 ETS78413.1 - 0.007 16.1 0.1 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain SIR2 PF02146.12 ETS78414.1 - 9.3e-54 181.8 0.0 1.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cu-oxidase_3 PF07732.10 ETS78415.1 - 5.8e-40 135.6 9.1 1.6e-39 134.3 4.2 2.9 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS78415.1 - 9.4e-37 125.5 6.5 1.7e-35 121.5 0.0 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS78415.1 - 4.3e-31 107.9 0.2 1.8e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase FAD_binding_4 PF01565.18 ETS78416.1 - 1.4e-21 76.3 0.4 2.8e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78416.1 - 0.00017 21.4 0.6 0.00063 19.5 0.4 2.1 1 0 0 1 1 1 1 Berberine and berberine like Lipase_GDSL PF00657.17 ETS78417.1 - 1.6e-10 41.1 0.3 2e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS78417.1 - 9.9e-08 32.3 0.2 1.1e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TetR_C_3 PF08362.6 ETS78417.1 - 0.14 11.8 0.2 11 5.7 0.1 2.2 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region Slp PF03843.8 ETS78419.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family COesterase PF00135.23 ETS78420.1 - 9.8e-59 199.4 0.2 1.4e-58 198.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF4493 PF14900.1 ETS78420.1 - 0.0092 15.6 0.1 9.2 5.8 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4493) Abhydrolase_3 PF07859.8 ETS78420.1 - 0.12 11.8 0.5 0.62 9.5 0.1 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Epimerase PF01370.16 ETS78421.1 - 6.6e-10 38.8 0.0 8.8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS78421.1 - 0.0002 21.3 0.0 0.0032 17.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS78421.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS78421.1 - 0.0021 17.0 0.0 0.099 11.5 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 ETS78421.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.11 ETS78422.1 - 2.1e-36 125.3 41.7 5.2e-36 124.0 28.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_2_N PF02837.13 ETS78423.1 - 2.1e-27 95.7 3.1 2.1e-27 95.7 2.1 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS78423.1 - 7.1e-14 52.1 0.2 7.1e-14 52.1 0.1 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 F5_F8_type_C PF00754.20 ETS78423.1 - 2.4e-08 33.8 1.6 2.4e-08 33.8 1.1 2.5 2 0 0 2 2 2 1 F5/8 type C domain adh_short PF00106.20 ETS78424.1 - 1.7e-29 102.9 4.9 2.1e-29 102.5 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78424.1 - 2.7e-25 89.5 0.4 3.3e-25 89.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78424.1 - 7.7e-14 51.7 2.5 1e-13 51.3 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78424.1 - 0.0023 17.3 1.6 0.0064 15.9 1.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS78424.1 - 0.021 14.8 2.5 0.11 12.4 1.7 1.9 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 ETS78425.1 - 7.3e-94 314.8 23.3 8.4e-94 314.6 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78425.1 - 2e-20 72.8 57.5 2.1e-19 69.4 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 ETS78425.1 - 0.11 11.9 1.4 0.27 10.7 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF1228 PF06779.9 ETS78425.1 - 0.24 11.4 13.0 1 9.4 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF3980 PF13140.1 ETS78425.1 - 0.49 10.7 6.9 2.8 8.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) CbtB PF09489.5 ETS78425.1 - 4.1 7.3 5.2 38 4.2 0.1 3.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) ADH_N PF08240.7 ETS78426.1 - 8.8e-30 102.6 0.8 8.8e-30 102.6 0.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS78426.1 - 6.8e-22 77.4 0.7 1.3e-21 76.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS78426.1 - 2e-05 25.4 0.0 6.3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 ETS78426.1 - 0.031 14.8 0.1 0.075 13.6 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS78426.1 - 0.039 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 ETS78427.1 - 9.1e-06 24.5 5.2 0.002 16.8 0.1 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain MerB PF03243.10 ETS78428.1 - 6e-27 94.0 0.0 8e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Alkylmercury lyase Sigma70_r3 PF04539.11 ETS78428.1 - 0.12 12.3 0.0 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 HET PF06985.6 ETS78429.1 - 9.9e-21 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.13 ETS78430.1 - 2.4e-08 33.3 1.0 2.4e-08 33.3 0.7 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 ETS78430.1 - 0.12 12.4 0.5 4.4 7.4 0.4 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family AA_permease PF00324.16 ETS78431.1 - 7.5e-34 116.8 33.4 2.5e-23 82.1 12.0 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 ETS78431.1 - 1.6e-20 73.0 33.1 4.6e-15 55.0 10.7 2.2 2 0 0 2 2 2 2 Amino acid permease Pkinase PF00069.20 ETS78432.1 - 8e-15 54.6 0.0 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78432.1 - 2.9e-08 33.1 0.0 8e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Str_synth PF03088.11 ETS78432.1 - 0.018 15.0 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Pox_ser-thr_kin PF05445.6 ETS78432.1 - 0.14 10.9 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Alginate_lyase PF05426.7 ETS78435.1 - 5e-16 58.8 2.1 5e-16 58.8 1.5 2.0 2 1 0 2 2 2 1 Alginate lyase Glyco_hydro_28 PF00295.12 ETS78436.1 - 0.0016 17.4 1.9 0.0096 14.9 1.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS78436.1 - 1.8 8.2 18.3 2.5 7.8 8.0 3.2 1 1 2 3 3 3 0 Right handed beta helix region PrpF PF04303.8 ETS78437.1 - 2.7e-87 292.9 0.1 4e-84 282.4 0.1 2.0 2 0 0 2 2 2 2 PrpF protein MGAT2 PF05060.9 ETS78439.1 - 0.061 12.2 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Fungal_trans PF04082.13 ETS78440.1 - 7.3e-23 80.7 0.0 3.3e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78440.1 - 1.6e-10 40.6 9.8 2.5e-10 40.0 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS78441.1 - 1.9e-47 161.8 0.0 2.2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 ETS78442.1 - 2.8e-119 398.6 25.5 3.2e-119 398.4 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78442.1 - 3.5e-28 98.3 26.8 3.5e-28 98.3 18.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 ETS78443.1 - 1.1e-29 103.2 47.8 1.5e-28 99.5 33.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_90 PF05686.7 ETS78444.1 - 8.8e-13 47.6 0.3 1e-11 44.1 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferase family 90 Zn_clus PF00172.13 ETS78447.1 - 2.3e-06 27.4 8.9 5e-06 26.3 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS78450.1 - 1.1e-12 47.3 4.1 1.3e-12 47.1 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78450.1 - 1e-06 27.6 1.4 1.3e-06 27.2 1.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 ETS78450.1 - 0.094 12.5 1.5 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 ETS78451.1 - 7.7e-06 24.8 17.2 8.7e-06 24.6 11.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 ETS78451.1 - 0.13 11.7 4.8 0.21 10.9 3.3 1.4 1 1 0 1 1 1 0 Fatty acid desaturase TAF1_subA PF14929.1 ETS78451.1 - 0.14 10.6 0.0 0.16 10.3 0.0 1.0 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Iso_dh PF00180.15 ETS78452.1 - 3e-75 253.3 0.0 4.6e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase PF00330.15 ETS78452.1 - 1.6e-54 185.1 0.0 3.3e-36 124.7 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS78452.1 - 4.5e-13 49.4 0.1 2e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain COesterase PF00135.23 ETS78453.1 - 5.8e-92 309.1 0.0 7.7e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78453.1 - 0.00069 19.2 1.5 0.0046 16.5 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS78453.1 - 0.035 13.3 0.1 0.068 12.3 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family HET PF06985.6 ETS78454.1 - 6.8e-28 97.5 0.6 1.3e-27 96.6 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) G-alpha PF00503.15 ETS78455.1 - 4.7e-64 216.4 0.1 8e-64 215.7 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS78455.1 - 6.2e-10 38.5 0.3 8.1e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETS78455.1 - 0.00045 19.6 0.0 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 ETS78455.1 - 0.0022 17.5 0.1 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETS78455.1 - 0.0034 17.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS78455.1 - 0.0038 17.7 0.0 0.68 10.4 0.0 2.7 1 1 0 2 2 2 1 Miro-like protein NOG1 PF06858.9 ETS78455.1 - 0.0077 16.0 0.1 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) AAA_15 PF13175.1 ETS78455.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 ETS78455.1 - 0.018 14.1 0.2 0.71 8.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 ETS78455.1 - 0.021 15.1 0.0 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 ETS78455.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETS78455.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain EzrA PF06160.7 ETS78455.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AA_permease_2 PF13520.1 ETS78457.1 - 4.7e-55 186.8 57.2 5.9e-55 186.5 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS78457.1 - 6.8e-15 54.3 42.4 1e-14 53.7 29.4 1.2 1 0 0 1 1 1 1 Amino acid permease CcmD PF04995.9 ETS78457.1 - 0.11 12.2 1.7 8.8 6.1 0.9 3.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) GFA PF04828.9 ETS78458.1 - 6.7e-14 51.6 3.1 1.1e-13 50.9 2.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer4_8 PF13183.1 ETS78458.1 - 0.18 11.8 6.7 0.35 10.9 4.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Rpr2 PF04032.11 ETS78458.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.4 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_28 PF00295.12 ETS78459.1 - 1.9e-46 158.5 10.0 2.9e-46 157.9 6.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 ETS78460.1 - 9.5e-26 90.0 0.5 8.8e-19 67.1 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase DNA_methylase PF00145.12 ETS78461.1 - 3.7e-38 131.5 0.4 1.7e-27 96.4 0.0 2.5 2 1 0 3 3 3 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.5 ETS78461.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF538 PF04398.7 ETS78461.1 - 0.08 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF538 Methyltransf_26 PF13659.1 ETS78461.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS78461.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_35 PF01301.14 ETS78462.1 - 1.4e-89 300.6 0.0 1.9e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 ETS78462.1 - 7.8e-52 175.2 0.8 1.1e-51 174.7 0.5 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 ETS78462.1 - 2.4e-51 172.6 0.6 7.7e-28 96.9 0.6 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 ETS78462.1 - 2.7e-13 49.1 0.0 1.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 ETS78462.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Amido_AtzD_TrzD PF09663.5 ETS78462.1 - 0.049 12.2 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Amidohydro_1 PF01979.15 ETS78463.1 - 5.2e-20 72.3 0.2 4.3e-19 69.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS78463.1 - 2.1e-10 41.0 6.5 1.5e-09 38.3 4.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS78463.1 - 3.3e-10 39.6 0.1 1.9e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS78463.1 - 2.6e-05 23.6 0.6 0.017 14.3 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Methyltransf_18 PF12847.2 ETS78464.1 - 0.0043 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS78464.1 - 0.17 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FbpA PF05833.6 ETS78465.1 - 9.6e-37 126.5 13.9 9.6e-37 126.5 9.6 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 ETS78465.1 - 1e-34 118.4 0.4 1e-34 118.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 ETS78465.1 - 1.6e-23 82.4 0.7 2.1e-22 78.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF814) eIF-5a PF01287.15 ETS78466.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_C1_2 PF03051.10 ETS78467.1 - 5e-149 496.5 0.0 6.1e-149 496.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 ETS78467.1 - 2.9e-07 30.6 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease HET PF06985.6 ETS78471.1 - 1.2e-28 100.0 0.4 4.5e-28 98.1 0.3 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pectate_lyase PF03211.8 ETS78472.1 - 3.3e-67 226.0 7.5 4.1e-67 225.7 5.2 1.0 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_3 PF00933.16 ETS78474.1 - 1.3e-82 277.1 0.0 1.9e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS78474.1 - 1.3e-60 204.7 0.4 6.4e-60 202.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS78474.1 - 8.3e-20 70.5 0.0 2.1e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS78474.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Aldedh PF00171.17 ETS78475.1 - 3e-116 388.5 0.0 3.9e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family E1-E2_ATPase PF00122.15 ETS78476.1 - 2.8e-12 46.1 0.3 7.5e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 ETS78476.1 - 3.8e-12 45.9 0.0 1.2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS78476.1 - 1.1e-11 45.3 0.9 3.1e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS78476.1 - 1.1e-10 42.3 4.4 1.3e-08 35.4 3.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS78476.1 - 0.042 13.4 0.4 0.099 12.2 0.3 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 ETS78478.1 - 5.4e-63 211.8 11.2 6.4e-63 211.6 7.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2622 PF11080.3 ETS78478.1 - 0.11 12.3 0.2 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Mg_trans_NIPA PF05653.9 ETS78479.1 - 3.9e-16 58.8 4.3 6.1e-16 58.2 3.0 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 ETS78479.1 - 0.00037 20.5 14.1 0.00071 19.6 0.2 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF373 PF04123.8 ETS78479.1 - 5.1 6.0 7.4 15 4.5 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF4485 PF14846.1 ETS78480.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DEAD PF00270.24 ETS78481.1 - 4.8e-43 146.5 0.0 8.9e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78481.1 - 1.2e-20 73.1 0.1 2.2e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS78481.1 - 0.00081 18.2 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 ETS78481.1 - 0.0019 16.6 0.0 1.5 7.0 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 ETS78481.1 - 0.078 12.2 0.1 6.4 5.9 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Ipi1_N PF12333.3 ETS78482.1 - 5.6e-16 58.3 0.0 1.8e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 ETS78482.1 - 0.029 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Robl_LC7 PF03259.12 ETS78483.1 - 1.1e-10 40.9 0.0 2.9e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain CorA PF01544.13 ETS78486.1 - 1.1e-12 47.6 0.7 2.1e-12 46.6 0.5 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cyclin PF08613.6 ETS78487.1 - 1.4e-13 51.5 0.0 1.4e-13 51.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 ETS78487.1 - 0.0042 16.6 0.3 0.0088 15.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain DEAD PF00270.24 ETS78488.1 - 8.7e-38 129.4 0.1 1.5e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78488.1 - 7.6e-24 83.3 0.0 1.8e-22 79.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS78488.1 - 3.3e-06 27.0 0.2 8.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 ETS78488.1 - 0.0004 19.7 0.0 0.00058 19.2 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.1 ETS78488.1 - 0.023 13.7 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pyr_redox_3 PF13738.1 ETS78489.1 - 1.2e-22 80.9 0.0 2.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS78489.1 - 1.2e-16 59.9 0.0 5.8e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS78489.1 - 1.5e-13 50.4 0.1 1.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS78489.1 - 1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS78489.1 - 4.8e-06 26.5 0.0 2.4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS78489.1 - 2.6e-05 23.4 0.0 6.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS78489.1 - 0.00012 21.9 0.2 0.0064 16.2 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 ETS78489.1 - 0.001 18.0 0.1 0.08 11.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS78489.1 - 0.002 16.6 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 ETS78489.1 - 0.0024 16.8 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS78489.1 - 0.0063 15.6 0.0 0.27 10.2 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 ETS78489.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS78489.1 - 0.02 15.2 0.6 13 6.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 ETS78489.1 - 0.024 12.8 0.0 2.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 ETS78489.1 - 0.025 13.4 0.1 0.047 12.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ETS78489.1 - 0.026 13.4 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 ETS78489.1 - 0.048 12.7 0.1 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DUF4147 PF13660.1 ETS78489.1 - 0.053 12.6 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Phage_tail_2 PF06199.6 ETS78489.1 - 0.064 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage major tail protein 2 Shikimate_DH PF01488.15 ETS78489.1 - 0.12 12.4 0.1 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 ETS78490.1 - 4.6e-43 147.2 39.0 4.6e-43 147.2 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78490.1 - 6.5e-07 28.2 33.1 5.4e-06 25.2 9.6 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter HOK_GEF PF01848.11 ETS78490.1 - 0.14 11.5 3.0 0.33 10.3 2.1 1.6 1 0 0 1 1 1 0 Hok/gef family Abhydrolase_5 PF12695.2 ETS78490.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS78491.1 - 2.8e-43 147.9 0.0 3.7e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS78491.1 - 0.021 13.5 0.0 0.044 12.4 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family DLH PF01738.13 ETS78491.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 ETS78492.1 - 1.2e-20 74.0 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS78492.1 - 3.2e-15 55.6 0.0 4.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Rpr2 PF04032.11 ETS78493.1 - 9.2e-25 86.3 1.8 1.9e-24 85.2 1.2 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 ETS78493.1 - 0.12 12.1 0.8 5.4 6.8 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger Glyco_transf_28 PF03033.15 ETS78494.1 - 6.7e-05 22.6 0.8 0.00017 21.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS78494.1 - 0.00014 20.6 0.0 0.00017 20.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ApbA PF02558.11 ETS78495.1 - 1.4e-25 89.4 0.0 2.7e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 ETS78495.1 - 2.7e-19 69.3 0.0 4.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MTBP_mid PF14919.1 ETS78495.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding DASH_Hsk3 PF08227.6 ETS78496.1 - 7.6e-21 74.0 4.5 1e-20 73.6 3.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Amidase PF01425.16 ETS78497.1 - 2.6e-70 237.4 0.1 1.9e-69 234.6 0.1 1.9 1 1 0 1 1 1 1 Amidase Yae1_N PF09811.4 ETS78498.1 - 3.1e-13 49.0 3.4 7.5e-13 47.7 2.3 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CENP-O PF09496.5 ETS78500.1 - 1.2e-22 79.9 0.1 2.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component HALZ PF02183.13 ETS78500.1 - 0.094 12.4 0.5 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Atg14 PF10186.4 ETS78500.1 - 0.12 11.2 1.8 0.15 10.9 0.2 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 ETS78500.1 - 0.22 11.4 3.4 1 9.3 1.9 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Acatn PF13000.2 ETS78501.1 - 4.7e-152 507.3 23.8 3.8e-76 256.7 6.0 3.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF4449 PF14613.1 ETS78502.1 - 0.0015 18.4 0.0 0.0049 16.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 ETS78502.1 - 0.011 15.3 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Pox_C4_C10 PF03336.8 ETS78502.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein MFS_1 PF07690.11 ETS78503.1 - 5.4e-41 140.4 48.1 3.8e-40 137.6 32.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily HemY_N PF07219.8 ETS78503.1 - 0.25 10.8 2.7 1.1 8.9 0.5 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF4448 PF14610.1 ETS78503.1 - 0.51 9.7 1.7 8.9 5.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) VCBS PF13517.1 ETS78505.1 - 5.9e-29 100.2 52.8 2e-11 44.0 1.2 8.2 3 2 4 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL PF00657.17 ETS78505.1 - 2.4e-14 53.7 0.6 3.8e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 ETS78505.1 - 1.9e-10 40.1 44.2 0.005 16.4 0.8 9.1 9 0 0 9 9 9 6 FG-GAP repeat Lipase_GDSL_2 PF13472.1 ETS78505.1 - 2e-09 37.8 0.1 5.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 ETS78505.1 - 9.1e-07 28.4 16.4 0.28 10.6 0.1 6.6 5 2 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 ETS78505.1 - 0.00045 20.0 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FGF PF00167.13 ETS78505.1 - 0.27 11.0 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Fibroblast growth factor NAD_binding_4 PF07993.7 ETS78506.1 - 3.7e-35 121.0 0.0 6.9e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS78506.1 - 2.2e-28 98.7 0.0 4.7e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS78506.1 - 2e-09 37.5 0.0 7.9e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 ETS78506.1 - 2.8e-08 33.5 0.0 6.2e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS78506.1 - 0.0007 19.5 2.7 0.0021 17.9 0.0 2.9 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 ETS78506.1 - 0.0028 17.3 1.1 0.045 13.4 0.2 2.9 2 1 0 2 2 2 1 KR domain DFP PF04127.10 ETS78507.1 - 1.5e-13 50.8 0.0 2.2e-05 24.1 0.0 3.3 1 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein CFEM PF05730.6 ETS78508.1 - 0.1 12.4 8.7 0.1 12.4 5.2 1.6 1 1 0 1 1 1 0 CFEM domain Pkinase PF00069.20 ETS78509.1 - 1.6e-58 197.9 0.0 8.2e-58 195.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78509.1 - 2.1e-28 99.1 0.2 2.5e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 ETS78509.1 - 5.5e-07 30.0 0.2 5.5e-07 30.0 0.1 2.7 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS78509.1 - 0.00023 20.2 0.2 0.0013 17.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 ETS78509.1 - 0.002 17.9 0.3 0.074 12.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Wbp11 PF09429.5 ETS78510.1 - 3.7e-23 81.2 14.4 3.7e-23 81.2 10.0 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2294 PF10057.4 ETS78510.1 - 0.0032 17.1 0.3 0.0053 16.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 ETS78510.1 - 0.018 14.1 4.6 0.026 13.6 3.2 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF1451 PF07295.6 ETS78510.1 - 0.039 13.7 0.8 0.072 12.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF3450 PF11932.3 ETS78510.1 - 0.061 12.5 4.3 0.091 12.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MFS_1 PF07690.11 ETS78511.1 - 8.1e-37 126.7 40.6 8.1e-37 126.7 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78511.1 - 2.5e-11 42.8 36.7 1.5e-06 27.1 7.8 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 ETS78511.1 - 0.00031 19.2 26.0 0.00033 19.1 15.4 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1625 PF07787.7 ETS78511.1 - 0.11 11.7 0.7 0.3 10.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Git3 PF11710.3 ETS78512.1 - 7.1e-11 42.0 7.1 3.3e-10 39.8 4.9 2.1 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 zf-C3H1 PF10650.4 ETS78513.1 - 0.00012 21.4 2.0 0.00019 20.8 1.4 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain zf-CCCH PF00642.19 ETS78513.1 - 0.00048 19.7 0.1 0.00086 18.9 0.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Myosin_head PF00063.16 ETS78514.1 - 1e-248 826.9 0.2 2.9e-248 825.4 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 ETS78514.1 - 2.4e-19 68.6 126.7 8.8e-14 50.2 32.3 7.3 3 2 2 6 6 6 4 Myosin tail Myosin_N PF02736.14 ETS78514.1 - 1.4e-06 27.8 0.2 3.4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 ETS78514.1 - 0.055 13.2 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain adh_short PF00106.20 ETS78515.1 - 8.2e-12 45.3 0.0 1.5e-05 25.0 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78515.1 - 0.0031 17.3 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78515.1 - 0.01 15.4 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 KR domain DUF3176 PF11374.3 ETS78516.1 - 6.7e-31 106.4 0.6 1.4e-30 105.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MMR_HSR1 PF01926.18 ETS78517.1 - 8.2e-12 45.1 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS78517.1 - 0.0027 17.0 0.1 0.0053 16.0 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS78517.1 - 0.0055 16.5 0.7 0.29 10.9 0.0 2.7 2 1 0 3 3 3 1 Dynamin family IIGP PF05049.8 ETS78517.1 - 0.0082 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 ETS78517.1 - 0.011 15.3 0.0 0.043 13.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 ETS78517.1 - 0.026 13.9 0.0 7.4 5.9 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETS78517.1 - 0.026 13.7 0.2 0.086 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 ETS78517.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Amidase PF01425.16 ETS78519.1 - 4.8e-56 190.4 0.0 2.3e-55 188.2 0.0 1.9 1 1 0 1 1 1 1 Amidase RRM_1 PF00076.17 ETS78520.1 - 3.8e-12 45.6 0.0 7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS78520.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 ETS78521.1 - 1.1 9.4 5.8 0.15 12.2 0.9 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Bac_luciferase PF00296.15 ETS78524.1 - 2e-53 181.5 0.3 3.1e-53 180.8 0.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 ETS78525.1 - 1.4e-28 99.6 23.1 1.4e-28 99.6 16.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PepSY_TM PF03929.11 ETS78525.1 - 0.017 15.4 0.5 0.017 15.4 0.4 4.3 5 0 0 5 5 5 0 PepSY-associated TM helix PepSY_TM_1 PF13172.1 ETS78525.1 - 3.8 7.3 10.4 0.19 11.5 2.0 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3736 PF12540.3 ETS78526.1 - 1 9.6 8.9 0.055 13.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) Prothymosin PF03247.9 ETS78526.1 - 1.6 8.9 7.2 3.2 7.9 5.0 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family PHD PF00628.24 ETS78527.1 - 1.8e-08 33.9 1.0 4.4e-08 32.6 0.7 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS78527.1 - 0.042 13.1 2.9 0.076 12.3 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Pyridox_ox_2 PF12900.2 ETS78528.1 - 7.8e-32 110.0 0.0 1.5e-31 109.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Oxysterol_BP PF01237.13 ETS78529.1 - 4.4e-129 430.0 0.8 1e-128 428.8 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 ETS78529.1 - 7.5e-17 61.4 0.4 3.2e-11 43.4 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78529.1 - 4.2e-16 57.8 0.6 8.9e-05 22.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS78529.1 - 1.1e-14 54.4 0.7 8.5e-09 35.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS78529.1 - 3.2e-14 52.6 1.1 1.9e-07 31.0 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 ETS78529.1 - 2.2e-12 47.0 0.5 4.3e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 ETS78529.1 - 5.6e-11 41.5 0.4 0.012 15.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.1 ETS78529.1 - 2.4e-08 33.9 1.6 6.7e-08 32.4 1.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Carboxyl_trans PF01039.17 ETS78530.1 - 3.9e-141 470.7 0.1 5.4e-141 470.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 ETS78530.1 - 0.0066 15.6 0.0 0.81 8.8 0.0 2.5 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 ETS78531.1 - 1.1e-41 142.3 1.0 1.8e-41 141.7 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS78531.1 - 2.1e-30 105.5 0.0 4.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS78531.1 - 3.1e-20 71.4 0.2 7.8e-20 70.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS78531.1 - 5.7e-13 49.2 0.1 1.2e-12 48.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 ETS78531.1 - 0.0046 16.3 0.2 0.021 14.1 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.1 ETS78532.1 - 4.1e-25 88.9 0.0 5.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS78532.1 - 2.1e-21 76.5 0.5 2.8e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS78532.1 - 2.8e-12 46.6 0.2 4.2e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78532.1 - 0.0069 15.8 0.1 0.013 14.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1752 PF08550.5 ETS78533.1 - 0.054 13.0 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) ThuA PF06283.6 ETS78534.1 - 1.6e-64 217.5 0.1 1.8e-64 217.4 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation TPR_12 PF13424.1 ETS78535.1 - 2.8e-36 123.3 10.8 4.5e-09 36.1 0.0 5.0 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETS78535.1 - 9.7e-34 114.3 10.2 2.4e-05 24.0 1.4 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETS78535.1 - 5.9e-11 41.4 2.8 0.57 10.2 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS78535.1 - 1.6e-09 37.5 3.2 1.5 9.6 0.1 7.7 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS78535.1 - 1.1e-08 34.1 6.0 0.33 10.8 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS78535.1 - 1.6e-08 34.9 0.7 0.06 14.0 0.2 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 ETS78535.1 - 3.1e-08 32.8 0.0 0.0033 16.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_1 PF00515.23 ETS78535.1 - 1.6e-07 30.6 2.1 1.3 8.7 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS78535.1 - 2.4e-07 30.4 1.7 0.14 12.6 0.8 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS78535.1 - 6.7e-07 28.8 4.5 0.0065 16.0 0.0 4.4 4 1 0 5 5 4 2 TPR repeat TPR_19 PF14559.1 ETS78535.1 - 2e-06 28.0 2.3 0.13 12.6 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS78535.1 - 8.4e-06 25.2 3.4 0.08 12.7 0.0 5.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS78535.1 - 1.1e-05 25.2 2.5 18 5.8 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.7 ETS78535.1 - 0.00035 20.2 0.0 0.0044 16.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Apc5 PF12862.2 ETS78535.1 - 0.045 13.5 1.7 0.21 11.4 0.0 2.9 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 ETS78535.1 - 0.26 11.8 5.5 35 5.1 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS78535.1 - 0.31 11.1 6.1 3.8 7.6 0.5 4.5 3 2 1 4 4 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 ETS78536.1 - 5.6e-69 228.5 0.0 1.2e-14 54.3 0.1 9.8 7 3 3 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78536.1 - 1.6e-45 150.7 17.9 0.00016 21.3 0.0 16.3 17 0 0 17 17 17 10 Ankyrin repeat Ank_3 PF13606.1 ETS78536.1 - 2.5e-41 135.5 8.7 0.00044 20.2 0.0 16.3 17 1 1 18 18 18 9 Ankyrin repeat Ank_4 PF13637.1 ETS78536.1 - 1.1e-38 130.8 1.2 7.7e-05 23.0 0.0 11.1 10 3 1 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS78536.1 - 3.6e-29 100.1 0.9 0.00072 19.7 0.0 12.5 10 2 4 14 14 14 6 Ankyrin repeats (many copies) Gp_dh_C PF02800.15 ETS78538.1 - 5.8e-54 181.7 0.3 8.4e-54 181.2 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 ETS78538.1 - 6.5e-45 152.7 0.1 1.4e-44 151.6 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS78538.1 - 0.012 15.4 0.2 0.22 11.4 0.0 2.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 ETS78538.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.19 ETS78539.1 - 6.8e-93 311.6 30.8 7.7e-93 311.5 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78539.1 - 3.8e-23 81.7 22.4 3.8e-23 81.7 15.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS78540.1 - 5.1e-25 87.8 0.0 9.1e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS78541.1 - 7e-30 103.9 27.7 7e-30 103.9 19.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_39 PF01229.12 ETS78542.1 - 0.0036 15.7 0.0 0.0048 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Aldedh PF00171.17 ETS78544.1 - 1.1e-162 541.5 0.9 1.3e-162 541.3 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 ETS78545.1 - 3e-20 72.2 0.1 4.9e-20 71.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78545.1 - 2.3e-09 37.0 11.6 3.9e-09 36.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS78546.1 - 2e-111 372.7 22.4 2.7e-111 372.3 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78546.1 - 4.4e-30 104.6 45.5 7.8e-26 90.6 17.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS78546.1 - 0.00016 20.0 2.3 0.00016 20.0 1.6 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 ETS78547.1 - 2e-26 92.9 0.3 2.9e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78547.1 - 1.3e-23 83.9 0.0 1.6e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78547.1 - 4.1e-14 52.6 0.1 8.1e-14 51.6 0.1 1.5 1 1 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.1 ETS78547.1 - 0.035 14.1 0.0 0.42 10.6 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_N PF00456.16 ETS78548.1 - 3.4e-107 358.1 0.0 4.5e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS78548.1 - 9e-35 119.7 0.0 6.2e-34 117.0 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS78548.1 - 2.5e-08 33.8 0.0 5.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 ETS78548.1 - 3.2e-08 32.8 0.0 1e-06 27.9 0.0 2.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 ETS78548.1 - 8.1e-05 22.2 0.4 0.0006 19.4 0.3 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 ETS78548.1 - 0.00038 19.9 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.15 ETS78548.1 - 0.055 12.1 0.1 0.095 11.3 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Transglut_core PF01841.14 ETS78548.1 - 0.082 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily ADH_N PF08240.7 ETS78549.1 - 2.2e-24 85.3 0.9 3.1e-24 84.8 0.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS78549.1 - 5.5e-13 48.6 0.4 1.2e-12 47.4 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 ETS78549.1 - 0.02 14.3 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 ETS78549.1 - 0.029 14.1 0.2 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 ThiF family AdoHcyase_NAD PF00670.16 ETS78549.1 - 0.032 14.0 0.1 0.91 9.3 0.0 2.3 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1272 PF06906.6 ETS78549.1 - 0.12 12.1 2.3 2.5 8.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Pyr_redox_3 PF13738.1 ETS78550.1 - 1.2e-26 94.0 0.0 2.3e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS78550.1 - 2.7e-16 58.8 0.1 1.8e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS78550.1 - 1.4e-12 47.3 0.0 4.3e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS78550.1 - 9.2e-08 31.3 0.2 5.4e-05 22.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS78550.1 - 1e-06 28.7 0.0 9.1e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS78550.1 - 4.8e-05 22.4 0.1 0.07 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS78550.1 - 6.5e-05 22.7 0.0 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 ETS78550.1 - 0.00025 21.1 0.2 1 9.4 0.0 3.3 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 ETS78550.1 - 0.011 14.9 0.2 0.024 13.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.19 ETS78550.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 ETS78550.1 - 0.049 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Ceramidase_alk PF04734.8 ETS78551.1 - 5.3e-15 54.3 1.0 1.1e-14 53.2 0.1 1.7 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase DUF2070 PF09843.4 ETS78551.1 - 0.0011 18.5 0.1 0.0028 17.1 0.0 1.7 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Collagen_bind PF05737.7 ETS78551.1 - 0.046 13.9 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Collagen binding domain Tannase PF07519.6 ETS78552.1 - 1.9e-99 333.5 3.9 3.7e-99 332.6 2.7 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Pyr_redox_dim PF02852.17 ETS78553.1 - 1.9e-22 79.3 0.0 6.4e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETS78553.1 - 3.8e-17 62.4 1.5 7.4e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS78553.1 - 4.1e-13 49.6 1.5 4.2e-09 36.5 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 ETS78553.1 - 0.0001 22.6 0.5 0.015 15.7 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ETS78553.1 - 0.00044 19.9 0.1 0.062 12.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 ETS78553.1 - 0.0011 19.0 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS78553.1 - 0.0037 16.2 0.7 0.39 9.5 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS78553.1 - 0.0039 16.7 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 ETS78553.1 - 0.0045 16.1 0.2 0.022 13.9 0.0 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 ETS78553.1 - 0.17 11.9 2.7 3.8 7.6 0.2 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS78553.1 - 0.18 10.6 4.7 0.74 8.5 0.1 2.7 2 1 0 2 2 2 0 FAD binding domain Abhydrolase_6 PF12697.2 ETS78554.1 - 1.2e-19 71.0 0.7 1.6e-19 70.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS78554.1 - 3e-15 56.2 0.0 1.6e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS78554.1 - 7.5e-10 37.8 0.3 0.00015 20.3 0.2 3.1 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 ETS78554.1 - 5.4e-06 26.0 0.1 2.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 ETS78554.1 - 0.00015 21.5 0.1 0.0004 20.1 0.1 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS78554.1 - 0.028 13.6 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1100 PF06500.6 ETS78554.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Transp_cyt_pur PF02133.10 ETS78555.1 - 5.5e-101 338.2 43.9 7.8e-101 337.7 30.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adenine_deam_C PF13382.1 ETS78556.1 - 8.6e-43 145.4 0.1 1.5e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 ETS78556.1 - 1.8e-18 67.3 0.4 8.6e-16 58.4 0.3 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS78556.1 - 6.7e-13 48.2 0.3 3.1e-12 46.1 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS78556.1 - 5.7e-11 42.9 0.2 0.00084 19.4 0.0 3.3 2 1 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 ETS78556.1 - 1.4e-06 27.8 0.0 0.003 16.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family UQ_con PF00179.21 ETS78558.1 - 8.8e-13 47.8 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 ETS78560.1 - 3.9e-58 197.2 0.1 4.7e-58 196.9 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Acyl_transf_3 PF01757.17 ETS78561.1 - 3.5e-26 91.8 27.7 4.7e-26 91.4 19.2 1.2 1 0 0 1 1 1 1 Acyltransferase family Hce2 PF14856.1 ETS78562.1 - 4.7e-11 42.4 0.2 8e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor TmoB PF06234.7 ETS78562.1 - 0.043 13.6 0.3 0.54 10.1 0.5 2.0 1 1 1 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Amidoligase_2 PF12224.3 ETS78563.1 - 1.2e-16 61.1 0.0 1.6e-14 54.1 0.0 2.6 1 1 0 1 1 1 1 Putative amidoligase enzyme FAD_binding_4 PF01565.18 ETS78564.1 - 2e-32 111.5 3.4 3.7e-32 110.6 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78564.1 - 3.8e-09 36.3 0.9 7.2e-09 35.4 0.6 1.4 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 ETS78565.1 - 2.4e-60 204.4 0.0 3e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLAC8 PF04749.12 ETS78566.1 - 3.5 8.2 10.3 6.7 7.3 0.1 2.5 2 0 0 2 2 2 0 PLAC8 family WD40 PF00400.27 ETS78567.1 - 1.3e-54 180.2 14.7 4.5e-09 35.8 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 ETS78567.1 - 5.5e-11 41.8 2.7 1.7e-10 40.2 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 ETS78567.1 - 2.6e-09 36.6 1.5 2.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like PQQ_2 PF13360.1 ETS78567.1 - 0.00012 21.5 0.7 1.2 8.5 0.1 3.3 2 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.3 ETS78567.1 - 0.00046 18.4 8.4 1.3 7.0 0.1 5.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Acetyltransf_3 PF13302.1 ETS78571.1 - 4.2e-13 49.6 0.0 1.1e-12 48.3 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS78571.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Amidoligase_2 PF12224.3 ETS78572.1 - 1.6e-19 70.5 0.0 1.1e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme DEAD PF00270.24 ETS78574.1 - 9.6e-20 70.7 0.1 1.1e-18 67.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78574.1 - 7.2e-19 67.4 0.0 8.9e-18 63.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS78574.1 - 6.9e-06 26.0 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS78574.1 - 0.0053 15.5 0.0 0.0088 14.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Phage_integrase PF00589.17 ETS78574.1 - 0.02 14.5 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family PTR2 PF00854.16 ETS78576.1 - 3.3e-27 95.2 14.0 5.5e-14 51.7 1.4 3.0 2 1 1 3 3 3 2 POT family CcmH PF03918.9 ETS78576.1 - 0.18 10.7 0.0 0.62 9.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein PFEMP PF03011.10 ETS78581.1 - 0.067 13.5 2.8 17 5.7 0.1 3.0 3 0 0 3 3 3 0 PFEMP DBL domain Antimicrobial21 PF14861.1 ETS78581.1 - 0.19 11.2 7.3 29 4.2 0.1 4.1 4 0 0 4 4 4 0 Plant antimicrobial peptide Chlam_OMP3 PF03503.8 ETS78581.1 - 9.1 6.5 19.7 16 5.7 0.4 3.5 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 3 F-box PF00646.28 ETS78582.1 - 0.019 14.6 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain GPI-anchored PF10342.4 ETS78583.1 - 4e-18 65.6 0.2 4e-18 65.6 0.2 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 ETS78583.1 - 0.28 9.4 3.4 0.33 9.1 2.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 ETS78583.1 - 1.7 7.8 14.3 2.2 7.4 9.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med13_C PF06333.7 ETS78583.1 - 2.2 6.7 12.2 3.1 6.2 8.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal TFIIA PF03153.8 ETS78583.1 - 3.2 7.5 11.4 3.8 7.3 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 ETS78583.1 - 3.6 7.1 11.8 4.8 6.7 8.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PAT1 PF09770.4 ETS78583.1 - 5 5.2 15.4 6 4.9 10.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.15 ETS78584.1 - 1.9e-54 185.1 1.5 2.9e-54 184.5 1.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Pkinase PF00069.20 ETS78585.1 - 1.5e-33 116.0 0.0 2.1e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78585.1 - 1.9e-20 73.0 0.0 5.2e-20 71.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase ATG16 PF08614.6 ETS78585.1 - 0.066 13.0 9.1 0.29 10.9 2.4 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Nnf1 PF03980.9 ETS78585.1 - 0.075 13.0 5.6 1.5 8.8 0.0 3.4 3 1 0 3 3 3 0 Nnf1 bZIP_1 PF00170.16 ETS78586.1 - 9.4e-06 25.5 2.7 1.7e-05 24.6 1.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF1478 PF07349.6 ETS78586.1 - 0.037 13.3 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) bZIP_Maf PF03131.12 ETS78586.1 - 0.28 11.5 7.6 0.12 12.7 1.5 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Band_7 PF01145.20 ETS78587.1 - 7e-32 110.7 1.1 1.2e-31 109.9 0.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 ETS78587.1 - 0.015 14.7 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sec7_N PF12783.2 ETS78588.1 - 1.1e-34 119.2 3.9 2.1e-33 115.1 0.0 3.4 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 ETS78588.1 - 3.9e-06 26.2 0.0 0.00085 18.7 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1981) HSDR_N PF04313.9 ETS78588.1 - 0.065 12.9 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) UQ_con PF00179.21 ETS78589.1 - 9.8e-16 57.4 0.0 1.2e-15 57.1 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS78589.1 - 0.084 12.7 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain Complex1_LYR PF05347.10 ETS78590.1 - 1.1e-09 37.9 0.0 3.3e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS78590.1 - 3.6e-09 36.7 0.1 3.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Complex1_LYR-like Peptidase_C50 PF03568.12 ETS78590.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C50 GLTSCR1 PF15249.1 ETS78590.1 - 0.17 12.0 3.5 0.44 10.6 2.4 1.7 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region p450 PF00067.17 ETS78591.1 - 1.9e-62 211.3 0.0 2.3e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hce2 PF14856.1 ETS78592.1 - 5.1e-17 61.5 1.9 8.6e-17 60.8 1.3 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor K_oxygenase PF13434.1 ETS78593.1 - 1.1e-107 359.9 0.0 1.3e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 ETS78593.1 - 1.6e-10 41.3 0.0 2.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS78593.1 - 1.6e-08 34.5 0.0 1.1e-07 31.7 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS78593.1 - 1.2e-05 25.2 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS78593.1 - 0.014 13.5 0.0 0.063 11.4 0.0 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DUF4147 PF13660.1 ETS78593.1 - 0.026 13.6 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) AMP-binding PF00501.23 ETS78594.1 - 6.9e-251 831.7 0.0 2.3e-90 302.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 ETS78594.1 - 4.2e-158 524.9 3.2 4.6e-28 97.9 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 ETS78594.1 - 2.1e-55 184.8 12.7 2.1e-11 43.9 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS78594.1 - 3.5e-22 79.1 0.3 1.3e-07 32.4 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 ETS78594.1 - 3.5e-06 26.7 1.8 0.14 11.6 0.4 4.7 4 1 0 4 4 4 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.10 ETS78594.1 - 0.0058 15.1 2.7 2.5 6.4 0.0 4.2 5 0 0 5 5 5 2 Transferase family HNOB PF07700.10 ETS78594.1 - 0.046 13.2 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding Peptidase_C14 PF00656.17 ETS78595.1 - 8.3e-72 241.8 0.0 1e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain MFS_1 PF07690.11 ETS78596.1 - 6.6e-24 84.2 38.9 6.6e-24 84.2 27.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 ETS78597.1 - 2.1e-48 165.2 0.0 2.5e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DHDPS PF00701.17 ETS78598.1 - 1.7e-40 138.4 0.0 4.7e-40 136.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 ETS78599.1 - 8e-31 106.8 0.0 1.4e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78599.1 - 1.2e-08 34.7 9.3 2.1e-08 33.9 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 ETS78600.1 - 2.1e-49 168.5 0.1 2.5e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 ETS78601.1 - 3.3e-35 121.4 33.6 3.3e-35 121.4 23.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF347 PF03988.7 ETS78601.1 - 0.015 15.1 0.6 0.062 13.1 0.0 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) MFS_1 PF07690.11 ETS78602.1 - 2.6e-38 131.6 30.7 2.8e-35 121.6 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78602.1 - 1.8e-09 36.6 1.5 4e-09 35.5 1.0 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS78602.1 - 0.001 17.3 2.0 0.0016 16.7 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 ETS78602.1 - 0.0022 16.7 1.2 0.0022 16.7 0.8 1.9 1 1 2 3 3 3 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 ETS78602.1 - 0.013 15.2 2.3 1.3 8.8 0.0 3.2 2 0 0 2 2 2 0 MFS_1 like family DUF4626 PF15422.1 ETS78602.1 - 0.16 11.8 0.1 0.86 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4626) SEN1_N PF12726.2 ETS78603.1 - 9.6e-147 490.0 0.3 1.3e-146 489.6 0.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 ETS78603.1 - 2.9e-68 229.9 2.3 2.9e-68 229.9 1.6 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 ETS78603.1 - 1.2e-60 204.2 0.0 2.3e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS78603.1 - 1.4e-10 40.7 0.1 4.6e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETS78603.1 - 3.5e-09 36.5 2.8 6.5e-07 29.1 0.3 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 ETS78603.1 - 3.4e-06 26.7 0.3 0.0046 16.5 0.1 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 ETS78603.1 - 0.0087 15.9 0.3 0.049 13.4 0.2 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RuvB_N PF05496.7 ETS78603.1 - 0.015 14.3 0.1 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS78603.1 - 0.018 14.4 0.1 0.058 12.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETS78603.1 - 0.35 11.1 8.5 0.18 12.0 0.2 2.9 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 ETS78604.1 - 4.6e-09 36.5 0.0 8.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Sirohm_synth_C PF14823.1 ETS78604.1 - 0.069 12.4 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Zn_clus PF00172.13 ETS78605.1 - 8.8e-09 35.1 13.0 1.4e-08 34.4 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.1 ETS78606.1 - 1.4e-44 152.7 2.9 2e-44 152.2 2.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 ETS78606.1 - 1.6e-24 85.9 0.0 2.2e-09 37.0 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase GATase_2 PF00310.16 ETS78607.1 - 2.5e-20 72.5 0.1 2.3e-17 62.7 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 ETS78607.1 - 3.3e-16 59.4 0.0 6.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 ETS78607.1 - 1.7e-14 53.5 0.0 3.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 ETS78607.1 - 2e-11 43.6 0.1 3.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 ETS78607.1 - 8.1e-07 27.9 0.0 1.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 ETS78607.1 - 0.15 11.5 0.8 1.6 8.3 0.0 2.8 4 0 0 4 4 4 0 Zinc-binding dehydrogenase Pirin PF02678.11 ETS78608.1 - 5.2e-26 90.6 1.0 1.6e-25 89.0 0.7 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 ETS78608.1 - 6.8e-05 22.2 5.5 0.00064 19.1 0.8 2.9 2 1 0 2 2 2 2 Cupin domain DnaJ-X PF14308.1 ETS78609.1 - 7.3 5.8 7.0 13 4.9 4.9 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Sugar_tr PF00083.19 ETS78610.1 - 2e-80 270.6 15.5 2.4e-80 270.3 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78610.1 - 4.7e-26 91.3 33.2 7.7e-21 74.1 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-P PF08510.7 ETS78610.1 - 0.0091 15.6 0.6 0.034 13.7 0.4 2.0 1 0 0 1 1 1 1 PIG-P Gate PF07670.9 ETS78610.1 - 0.08 12.8 8.3 0.066 13.1 0.8 2.6 2 0 0 2 2 2 0 Nucleoside recognition Transaldolase PF00923.14 ETS78611.1 - 3.8e-27 95.1 0.0 4.7e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Aldo_ket_red PF00248.16 ETS78612.1 - 6.5e-53 179.3 0.0 7.7e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Orbi_NS1 PF01718.11 ETS78612.1 - 0.2 9.6 0.0 0.36 8.8 0.0 1.4 1 1 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Fungal_trans PF04082.13 ETS78613.1 - 7e-10 38.2 1.1 8.8e-10 37.8 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78613.1 - 3.8e-06 26.7 1.7 7.4e-06 25.7 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 ETS78613.1 - 0.0057 15.2 0.2 0.0081 14.7 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease Trypan_PARP PF05887.6 ETS78613.1 - 0.01 15.6 8.8 0.018 14.8 6.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) adh_short PF00106.20 ETS78614.1 - 2.7e-28 98.9 0.2 3.8e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78614.1 - 4.2e-20 72.5 0.0 8.3e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78614.1 - 5.7e-10 39.1 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78614.1 - 0.01 15.2 0.1 0.08 12.3 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ETS78614.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 ETS78615.1 - 3.8e-25 88.7 1.1 4.7e-25 88.4 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78615.1 - 2.3e-20 73.3 0.0 3.1e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78615.1 - 1.7e-16 60.4 0.4 2.4e-16 59.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78615.1 - 1e-06 28.3 0.0 2.4e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS78615.1 - 1.3e-05 24.0 0.1 2.4e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS78615.1 - 0.0012 17.8 0.1 0.15 10.9 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 ETS78615.1 - 0.039 12.8 0.0 0.099 11.5 0.0 1.7 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS78615.1 - 0.11 11.3 0.0 0.25 10.1 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_17 PF13207.1 ETS78616.1 - 4.8e-07 30.6 0.0 2.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS78616.1 - 9.4e-06 25.5 1.0 0.00015 21.6 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS78616.1 - 5.5e-05 23.4 0.0 0.00052 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS78616.1 - 0.0013 18.7 1.7 0.0028 17.6 0.1 2.3 2 1 1 3 3 3 1 AAA ATPase domain ArgK PF03308.11 ETS78616.1 - 0.0047 15.7 0.1 0.0072 15.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 ETS78616.1 - 0.0054 16.4 0.0 0.0054 16.4 0.0 2.9 4 1 0 4 4 4 1 Part of AAA domain AAA_28 PF13521.1 ETS78616.1 - 0.0058 16.5 0.5 0.027 14.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 ETS78616.1 - 0.021 13.8 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 ETS78616.1 - 0.022 13.5 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.13 ETS78616.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 ETS78616.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 ETS78616.1 - 0.035 12.9 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 ETS78616.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 ETS78616.1 - 0.059 12.4 0.2 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 ETS78616.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 ETS78616.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS78616.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 ETS78616.1 - 0.19 10.7 0.2 0.34 10.0 0.2 1.3 1 0 0 1 1 1 0 KaiC PhyH PF05721.8 ETS78617.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS78617.1 - 0.00031 19.3 0.1 0.78 8.1 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) ADH_N PF08240.7 ETS78618.1 - 8e-22 77.0 0.1 1.6e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS78618.1 - 1.2e-19 70.1 0.1 1.8e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ETS78618.1 - 0.00012 21.7 0.4 0.00018 21.1 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 ETS78618.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.1 ETS78618.1 - 0.014 16.2 0.0 0.062 14.1 0.0 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 ETS78618.1 - 0.014 15.9 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS78618.1 - 0.027 13.6 0.1 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS78618.1 - 0.036 13.7 0.3 0.053 13.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 ETS78618.1 - 0.04 14.2 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain PrmA PF06325.8 ETS78618.1 - 0.068 12.2 0.1 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.20 ETS78619.1 - 3.4e-29 101.9 5.0 4.9e-29 101.3 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78619.1 - 3.4e-20 72.8 0.4 4.3e-20 72.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78619.1 - 2.5e-14 53.3 2.9 4.1e-14 52.6 2.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS78619.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FTCD_C PF04961.7 ETS78619.1 - 0.34 10.3 4.4 7 6.0 0.4 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Sugar_tr PF00083.19 ETS78620.1 - 1.3e-66 225.0 18.7 1.6e-66 224.7 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS78620.1 - 7.6e-22 77.4 25.0 3.7e-16 58.8 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DeoC PF01791.4 ETS78621.1 - 2.4e-32 112.1 0.3 2.7e-32 111.9 0.2 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase MFS_1 PF07690.11 ETS78622.1 - 1.2e-43 149.1 56.5 3.5e-42 144.3 37.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS78622.1 - 6.3e-16 57.6 20.4 6.3e-16 57.6 14.1 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS78622.1 - 8.3e-14 51.0 17.8 8.3e-14 51.0 12.4 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter MACPF PF01823.14 ETS78623.1 - 3e-05 23.8 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain APG17 PF04108.7 ETS78624.1 - 0.0091 14.8 0.4 0.38 9.4 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 DUF1910 PF08928.5 ETS78624.1 - 0.19 11.7 2.3 0.81 9.7 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Rootletin PF15035.1 ETS78624.1 - 0.28 11.1 5.0 0.48 10.3 1.2 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HET PF06985.6 ETS78625.1 - 6.2e-33 113.8 0.7 4.9e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Tim54 PF11711.3 ETS78625.1 - 0.0035 16.0 5.5 0.0052 15.4 3.8 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 ETS78625.1 - 0.016 13.1 15.1 0.021 12.7 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.9 ETS78625.1 - 0.065 13.3 32.5 0.12 12.5 22.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family BUD22 PF09073.5 ETS78625.1 - 0.069 12.2 9.7 0.095 11.7 6.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 ETS78625.1 - 0.1 10.6 9.6 0.36 8.8 7.2 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF3306 PF11748.3 ETS78625.1 - 0.2 12.3 9.7 2.6 8.7 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Tfb4 PF03850.9 ETS78625.1 - 0.27 10.4 1.5 0.31 10.2 0.0 1.8 2 0 0 2 2 1 0 Transcription factor Tfb4 DDHD PF02862.12 ETS78625.1 - 0.33 10.7 1.7 0.52 10.0 1.1 1.2 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 ETS78625.1 - 0.33 10.3 11.0 0.55 9.6 7.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 ETS78625.1 - 1.1 7.9 18.0 1.6 7.3 12.5 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.7 ETS78625.1 - 1.5 8.0 18.2 2.1 7.5 12.6 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 ETS78625.1 - 1.7 8.4 8.7 3.4 7.4 6.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Ycf1 PF05758.7 ETS78625.1 - 1.8 6.1 6.5 2.3 5.8 4.5 1.1 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 ETS78625.1 - 3.2 6.9 11.6 4.8 6.3 8.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_Ag35 PF03286.9 ETS78625.1 - 5.2 6.5 11.1 8.3 5.8 7.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prog_receptor PF02161.10 ETS78625.1 - 6.2 5.5 8.9 9 4.9 6.2 1.1 1 0 0 1 1 1 0 Progesterone receptor RRN3 PF05327.6 ETS78625.1 - 6.9 4.6 8.4 9.9 4.1 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 ETS78625.1 - 7.8 6.5 18.9 14 5.6 13.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 ETS78625.1 - 9.2 6.5 22.1 23 5.2 15.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETS78625.1 - 9.5 3.9 6.0 13 3.4 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_L_2 PF13656.1 ETS78627.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Phage_CP76 PF06892.6 ETS78628.1 - 0.064 12.5 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) SnoaL_2 PF12680.2 ETS78629.1 - 1.3e-07 31.9 0.0 1.7e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain TPR_12 PF13424.1 ETS78630.1 - 6.5e-10 38.8 10.3 2.7e-05 23.9 0.0 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS78630.1 - 0.00021 21.1 9.7 0.088 12.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS78630.1 - 0.025 15.0 4.8 3.7 8.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ELYS PF13934.1 ETS78630.1 - 0.027 14.2 0.5 0.11 12.2 0.0 2.0 1 1 0 2 2 2 0 Nuclear pore complex assembly TPR_2 PF07719.12 ETS78630.1 - 0.027 14.3 9.1 3.6 7.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS78630.1 - 0.045 13.5 1.6 32 4.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS78630.1 - 0.15 12.7 12.6 2.8 8.8 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETS78630.1 - 0.39 10.4 9.8 3.4 7.3 2.4 3.5 3 1 1 4 4 4 0 TPR repeat TPR_20 PF14561.1 ETS78630.1 - 2.4 8.3 7.2 32 4.7 3.3 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 ETS78632.1 - 1.7e-33 115.8 0.0 4e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78632.1 - 1.2e-22 80.1 0.0 9.4e-19 67.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETS78632.1 - 0.003 17.3 0.8 0.013 15.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS78632.1 - 0.046 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAD_binding_4 PF01565.18 ETS78633.1 - 2.8e-31 107.8 0.5 5e-31 107.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78633.1 - 4.3e-19 68.1 3.2 4.5e-19 68.1 0.7 2.3 3 0 0 3 3 3 1 Berberine and berberine like FAD_binding_4 PF01565.18 ETS78635.1 - 9.3e-24 83.4 0.4 1.6e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS78635.1 - 2.1e-05 24.3 0.0 5.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like TPR_10 PF13374.1 ETS78637.1 - 3.2e-31 106.3 1.8 5.5e-12 45.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS78637.1 - 6.2e-22 77.3 0.1 2.6e-13 49.7 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS78637.1 - 2.7e-10 39.2 1.1 0.069 12.9 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 ETS78637.1 - 8.6e-08 31.3 0.0 0.0084 14.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_17 PF13431.1 ETS78637.1 - 6.8e-05 22.7 1.1 1.7 9.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS78637.1 - 0.00014 21.3 0.0 2.9 7.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS78637.1 - 0.00048 19.8 1.1 5.2 7.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS78637.1 - 0.004 16.8 0.7 6.2 6.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS78637.1 - 0.018 15.7 0.1 0.018 15.7 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 ETS78637.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 ETS78637.1 - 0.037 13.6 0.3 0.22 11.1 0.0 2.5 2 1 1 3 3 3 0 TPR repeat TPR_4 PF07721.9 ETS78637.1 - 0.044 14.2 1.3 7.4 7.3 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS78637.1 - 0.14 12.5 1.2 3.7 7.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS78637.1 - 0.17 12.3 4.7 19 6.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Tetraspannin PF00335.15 ETS78638.1 - 5.9e-06 25.7 0.1 8.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Tetraspanin family Zn_clus PF00172.13 ETS78639.1 - 2e-05 24.4 11.5 3.5e-05 23.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15 PF09606.5 ETS78639.1 - 0.18 9.9 47.5 0.23 9.6 32.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 ETS78639.1 - 0.29 10.9 25.5 0.4 10.5 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETS78639.1 - 0.35 9.0 38.0 0.44 8.7 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_14 PF13428.1 ETS78639.1 - 0.84 10.4 9.5 3 8.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SPX PF03105.14 ETS78639.1 - 1.4 8.5 13.7 0.59 9.8 7.0 2.0 2 0 0 2 2 2 0 SPX domain Dickkopf_N PF04706.7 ETS78639.1 - 1.8 8.8 10.8 5.5 7.2 7.5 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ndc1_Nup PF09531.5 ETS78639.1 - 2.7 6.3 9.4 3.2 6.0 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Paf1 PF03985.8 ETS78639.1 - 3.2 6.3 17.5 5 5.7 12.1 1.4 1 0 0 1 1 1 0 Paf1 DUF2470 PF10615.4 ETS78641.1 - 3.1e-17 62.5 0.1 4.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Fimbrial PF00419.15 ETS78642.1 - 0.063 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Fimbrial protein FAD_binding_4 PF01565.18 ETS78645.1 - 9.8e-24 83.4 0.6 1.4e-23 82.9 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Lactonase PF10282.4 ETS78647.1 - 0.00037 19.6 0.3 0.1 11.6 0.0 2.8 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller CW_binding_2 PF04122.7 ETS78647.1 - 0.053 13.7 0.2 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Lambda_CIII PF02061.11 ETS78648.1 - 0.0057 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Lambda Phage CIII bZIP_1 PF00170.16 ETS78648.1 - 0.089 12.7 10.9 0.14 12.1 7.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF4337 PF14235.1 ETS78648.1 - 0.49 10.2 2.8 0.74 9.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Lipase_GDSL_2 PF13472.1 ETS78649.1 - 0.00052 20.1 1.6 0.0014 18.7 1.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS78649.1 - 0.032 14.0 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_hydro_28 PF00295.12 ETS78650.1 - 5.1e-42 143.9 0.5 6.3e-42 143.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 HET PF06985.6 ETS78651.1 - 1.2e-22 80.6 0.0 2.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS78652.1 - 3.9e-33 114.5 0.1 8.6e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3855 PF12967.2 ETS78652.1 - 0.069 12.7 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) ADH_zinc_N PF00107.21 ETS78654.1 - 2.8e-09 36.5 0.0 8.6e-09 35.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS78654.1 - 3.8e-07 29.8 0.1 2e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain LGFP PF08310.6 ETS78654.1 - 0.087 12.4 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 LGFP repeat Abhydrolase_6 PF12697.2 ETS78655.1 - 3.3e-09 36.9 0.1 4.5e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS78655.1 - 0.003 17.3 0.0 0.005 16.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CFEM PF05730.6 ETS78656.1 - 0.032 14.0 0.6 0.066 13.0 0.4 1.6 1 0 0 1 1 1 0 CFEM domain Glyco_hydro_61 PF03443.9 ETS78657.1 - 6.5e-53 179.7 0.1 9.1e-53 179.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_1 PF00583.19 ETS78658.1 - 2.5e-10 40.2 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS78658.1 - 2.9e-06 27.3 0.0 5.8e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS78658.1 - 0.00081 19.5 0.1 0.002 18.2 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 ETS78658.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family DUF2435 PF10363.4 ETS78659.1 - 4.3e-14 52.1 0.7 1.2e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 ETS78659.1 - 3.7e-09 35.8 0.0 1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Dymeclin PF09742.4 ETS78659.1 - 0.016 13.3 0.3 0.023 12.8 0.2 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Ribosomal_S7e PF01251.13 ETS78660.1 - 0.14 11.6 0.1 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e ACBP PF00887.14 ETS78661.1 - 8.1e-30 102.3 0.0 2.3e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein LMBR1 PF04791.11 ETS78661.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribonuclease_3 PF00636.21 ETS78662.1 - 1e-13 51.7 0.0 2.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETS78662.1 - 1.4e-12 47.7 0.0 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 ETS78662.1 - 0.008 16.7 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif GIT1_C PF12205.3 ETS78662.1 - 0.038 13.8 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1313 PF07011.6 ETS78662.1 - 0.05 13.2 0.3 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) MRP-S33 PF08293.6 ETS78663.1 - 1.1e-25 89.4 0.2 1.3e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 ETS78664.1 - 7.3e-36 119.6 0.9 2.2e-06 26.8 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Het-C PF07217.6 ETS78665.1 - 2.6e-284 944.0 0.0 3e-284 943.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.16 ETS78666.1 - 8e-42 143.3 0.0 1.5e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETS78666.1 - 0.0002 21.1 0.0 0.23 11.1 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 ETS78666.1 - 0.00067 19.1 0.0 0.0027 17.1 0.0 2.0 2 1 0 2 2 2 1 Protein phosphatase 2C CITED PF04487.7 ETS78666.1 - 0.2 11.8 2.1 0.47 10.6 1.0 1.9 2 0 0 2 2 2 0 CITED DAO PF01266.19 ETS78669.1 - 1.5e-22 79.9 0.7 3.6e-22 78.7 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS78669.1 - 0.00033 20.6 0.1 0.00075 19.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS78669.1 - 0.0017 18.7 0.8 0.0074 16.6 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS78669.1 - 0.0073 15.3 0.4 0.019 13.9 0.1 1.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 ETS78669.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 ETS78669.1 - 0.045 12.6 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS78669.1 - 0.2 10.0 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Lyase_1 PF00206.15 ETS78670.1 - 3.3e-19 69.2 0.0 5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 ETS78670.1 - 1.5e-15 56.9 0.0 3.7e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus adh_short PF00106.20 ETS78671.1 - 6.4e-30 104.2 0.2 9.2e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78671.1 - 3.3e-23 82.6 0.0 4.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS78671.1 - 2.1e-10 40.5 0.1 3.6e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS78671.1 - 0.0049 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS78671.1 - 0.017 14.2 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 ETS78671.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 ETS78671.1 - 0.023 14.4 0.2 0.058 13.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETS78671.1 - 0.028 13.8 0.0 0.092 12.1 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS78671.1 - 0.035 14.1 0.1 0.098 12.6 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding PAP2 PF01569.16 ETS78672.1 - 3.5e-17 62.3 3.4 3.5e-17 62.3 2.4 1.9 2 0 0 2 2 2 1 PAP2 superfamily Glyco_hydro_43 PF04616.9 ETS78673.1 - 2.8e-41 141.5 7.0 3.1e-41 141.3 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 ETS78673.1 - 0.0041 15.8 0.0 0.0095 14.6 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF377) DUF4608 PF15381.1 ETS78673.1 - 0.038 14.1 0.5 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) DAO PF01266.19 ETS78674.1 - 1.6e-51 175.3 0.1 1.8e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS78674.1 - 7.8e-08 32.2 0.0 9.2e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS78674.1 - 6e-05 22.9 0.1 0.00039 20.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS78674.1 - 6.5e-05 23.0 0.0 0.0086 16.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS78674.1 - 0.0024 16.7 0.1 0.0053 15.6 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS78674.1 - 0.0039 16.3 0.0 0.0089 15.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 ETS78674.1 - 0.044 12.7 0.0 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS78674.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP-grasp_2 PF08442.5 ETS78676.1 - 7.3e-08 32.0 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 ETS78677.1 - 1.8e-18 66.4 0.0 8.2e-16 57.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 ETS78677.1 - 5.2e-18 65.3 0.0 1.7e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 ETS78677.1 - 1.1e-14 54.3 0.2 2.1e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 ETS78677.1 - 4.2e-06 26.3 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.15 ETS78678.1 - 3.6e-16 58.4 0.0 4.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 ETS78679.1 - 3.7e-55 185.8 0.1 4.3e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 MRG Utp14 PF04615.8 ETS78680.1 - 3.9 5.5 26.5 5.6 4.9 18.3 1.2 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 ETS78680.1 - 9.4 4.3 27.4 14 3.7 19.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Tudor-knot PF11717.3 ETS78682.1 - 8.6e-09 34.9 0.3 1.3e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Herpes_UL37_2 PF07413.6 ETS78682.1 - 0.015 14.1 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Lipocalin_5 PF13924.1 ETS78682.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like domain Chromo PF00385.19 ETS78682.1 - 0.026 14.1 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 ETS78682.1 - 0.068 13.3 0.1 0.099 12.8 0.1 1.2 1 0 0 1 1 1 0 PWWP domain Phytoreo_Pns PF05451.6 ETS78682.1 - 0.1 11.2 0.2 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Cnl2_NKP2 PF09447.5 ETS78683.1 - 2.1e-26 91.3 1.3 2.1e-26 91.3 0.9 2.0 3 0 0 3 3 3 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.1 ETS78683.1 - 0.0058 16.6 2.7 0.011 15.7 0.2 2.1 2 0 0 2 2 2 1 Syntaxin-like protein DUF2365 PF10157.4 ETS78683.1 - 0.026 14.3 0.2 0.06 13.2 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) GAS PF13851.1 ETS78683.1 - 0.16 11.1 6.3 0.14 11.3 0.8 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.7 ETS78683.1 - 0.16 11.7 4.3 1.6 8.4 0.3 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 ETS78683.1 - 0.24 11.1 7.4 0.63 9.7 0.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein KfrA_N PF11740.3 ETS78683.1 - 1.4 9.4 7.7 5.9 7.3 1.0 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1843 PF08898.5 ETS78683.1 - 1.5 8.9 6.0 1.4 8.9 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) APG6 PF04111.7 ETS78683.1 - 2.5 7.0 6.6 1.9 7.4 3.2 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 ETS78683.1 - 9.1 5.8 8.9 30 4.1 6.2 1.9 1 1 0 1 1 1 0 IncA protein CENP-Q PF13094.1 ETS78685.1 - 6.2e-28 97.8 0.6 6.2e-28 97.8 0.4 3.8 3 2 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.20 ETS78686.1 - 2.1e-15 56.5 0.0 8.1e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78686.1 - 7.8e-09 34.9 0.0 5.8e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 ETS78687.1 - 1.3e-09 37.2 27.6 2.4e-09 36.3 16.1 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS78687.1 - 1.4e-06 27.9 1.3 3.5e-06 26.5 0.9 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 ETS78687.1 - 2.3e-06 26.4 7.2 4e-06 25.6 5.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS78687.1 - 1.5 7.1 18.5 0.035 12.5 4.6 2.6 1 1 2 3 3 3 0 MFS/sugar transport protein MR_MLE_C PF13378.1 ETS78688.1 - 8.1e-35 119.1 0.0 1.5e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 ETS78688.1 - 5e-17 61.9 0.0 9.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 ETS78688.1 - 9.9e-08 32.4 0.0 2.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Aldo_ket_red PF00248.16 ETS78689.1 - 6.9e-58 195.7 0.0 1e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.5 ETS78689.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) DHDPS PF00701.17 ETS78690.1 - 8.8e-30 103.2 0.0 1.1e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.7 ETS78690.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) NAD_binding_4 PF07993.7 ETS78691.1 - 5.3e-39 133.6 0.0 1.2e-38 132.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 ETS78691.1 - 7e-38 130.1 0.0 1.2e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 ETS78691.1 - 9.3e-13 48.1 0.0 1.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS78691.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 ETS78691.1 - 0.0017 18.0 0.4 0.0054 16.4 0.3 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS78691.1 - 0.002 16.8 0.0 0.01 14.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS78691.1 - 0.0027 17.6 0.5 0.0071 16.2 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ATP-synt_ab PF00006.20 ETS78691.1 - 0.057 12.9 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MFS_1 PF07690.11 ETS78692.1 - 3.8e-37 127.8 21.4 3.8e-37 127.8 14.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78692.1 - 6.9e-13 47.9 13.0 9e-13 47.5 9.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 ETS78693.1 - 2.3e-25 88.9 0.5 4.3e-25 88.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78693.1 - 1.1e-07 31.6 8.5 1.1e-07 31.6 5.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.12 ETS78694.1 - 1.4e-118 395.1 0.5 2.1e-118 394.6 0.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS78694.1 - 2.8e-43 147.6 2.2 5.4e-43 146.6 1.5 1.5 1 0 0 1 1 1 1 DAK2 domain Peptidase_MA_2 PF13485.1 ETS78695.1 - 2.6e-05 24.2 0.3 4.5e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 ETS78695.1 - 0.0091 15.9 0.9 0.47 10.4 0.7 2.5 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Aminotran_1_2 PF00155.16 ETS78696.1 - 6.5e-36 124.0 0.0 8.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS78696.1 - 0.13 11.3 0.0 0.75 8.8 0.0 2.0 2 0 0 2 2 2 0 Beta-eliminating lyase BUD22 PF09073.5 ETS78698.1 - 3.6 6.5 8.9 5 6.0 6.2 1.2 1 0 0 1 1 1 0 BUD22 Meth_synt_2 PF01717.13 ETS78699.1 - 9.5e-146 484.8 0.0 8.4e-139 462.0 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS78699.1 - 1.8e-123 411.8 0.1 9.5e-112 373.2 0.0 3.3 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 ETS78699.1 - 0.028 13.3 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Transp_cyt_pur PF02133.10 ETS78701.1 - 2.9e-91 306.2 31.8 3.6e-91 305.9 22.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SnoaL_4 PF13577.1 ETS78702.1 - 0.044 13.6 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.13 ETS78703.1 - 1.4e-05 24.1 4.6 2e-05 23.5 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATase PF00117.23 ETS78704.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Beta_elim_lyase PF01212.16 ETS78704.1 - 0.029 13.5 0.0 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase MFS_1 PF07690.11 ETS78705.1 - 4.7e-29 101.1 28.6 4.7e-29 101.1 19.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Imp-YgjV PF10688.4 ETS78705.1 - 0.0081 15.5 4.0 0.0081 15.5 2.7 2.6 2 0 0 2 2 2 1 Bacterial inner membrane protein TPR_12 PF13424.1 ETS78706.1 - 2.3e-36 123.5 22.4 5.4e-07 29.4 0.4 6.6 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETS78706.1 - 7.6e-34 114.6 17.3 0.00057 19.7 0.1 11.8 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 ETS78706.1 - 3.2e-24 84.8 21.5 5.5e-07 29.6 0.1 7.3 2 2 6 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS78706.1 - 2.9e-18 65.9 16.7 0.018 15.3 0.0 10.0 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS78706.1 - 6.4e-18 63.0 22.3 0.073 12.9 0.1 11.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS78706.1 - 7.4e-16 58.3 19.4 0.09 13.4 0.2 9.5 7 3 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS78706.1 - 2.6e-15 55.8 13.3 0.0039 16.8 0.1 7.2 4 2 3 7 7 7 6 TPR repeat TPR_6 PF13174.1 ETS78706.1 - 3.9e-15 55.1 5.0 0.57 10.7 0.0 10.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS78706.1 - 5e-15 54.1 18.3 0.027 14.3 0.1 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat NB-ARC PF00931.17 ETS78706.1 - 4.7e-13 48.6 0.0 1.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 ETS78706.1 - 1.8e-11 43.5 16.1 4.9 8.0 0.1 11.2 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS78706.1 - 2.6e-09 36.2 9.4 0.61 9.7 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat PPR PF01535.15 ETS78706.1 - 3.1e-07 29.9 3.9 30 4.8 0.0 8.8 11 0 0 11 11 8 0 PPR repeat AAA_22 PF13401.1 ETS78706.1 - 3.5e-07 30.4 0.0 1.8e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.1 ETS78706.1 - 5.6e-06 25.7 2.8 8.1 6.4 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat Paf67 PF10255.4 ETS78706.1 - 8.7e-06 24.8 0.1 0.27 10.0 0.0 4.8 3 2 2 6 6 6 1 RNA polymerase I-associated factor PAF67 NACHT PF05729.7 ETS78706.1 - 2.8e-05 23.8 0.0 7.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_20 PF14561.1 ETS78706.1 - 0.00032 20.7 32.6 4.7 7.4 0.2 10.1 4 2 7 11 11 11 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 ETS78706.1 - 0.0033 16.4 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily SRP54 PF00448.17 ETS78706.1 - 0.0037 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain TPR_17 PF13431.1 ETS78706.1 - 0.032 14.4 3.8 34 4.9 0.0 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR_3 PF13812.1 ETS78706.1 - 0.34 11.2 4.6 89 3.7 0.0 5.7 6 0 0 6 6 5 0 Pentatricopeptide repeat domain Syntaxin-18_N PF10496.4 ETS78706.1 - 2.7 7.8 7.7 19 5.1 0.1 4.4 3 2 3 6 6 5 0 SNARE-complex protein Syntaxin-18 N-terminus Transp_cyt_pur PF02133.10 ETS78707.1 - 2.7e-101 339.3 43.3 3.1e-101 339.0 30.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aminotran_1_2 PF00155.16 ETS78708.1 - 1.3e-18 67.0 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS78708.1 - 0.0035 15.9 0.0 0.0048 15.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Amidase PF01425.16 ETS78709.1 - 8.4e-83 278.6 0.1 1.7e-82 277.6 0.1 1.4 1 1 0 1 1 1 1 Amidase DAO PF01266.19 ETS78710.1 - 5.9e-24 84.6 0.0 9.8e-24 83.9 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS78710.1 - 0.089 12.6 1.3 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_30 PF02055.11 ETS78711.1 - 9.1e-20 70.3 5.6 7.9e-11 40.8 3.8 3.0 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 ETS78711.1 - 7.4e-18 64.6 0.1 1.9e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 CBM_1 PF00734.13 ETS78711.1 - 1.1e-10 40.9 16.1 1.1e-10 40.9 11.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Polysacc_deac_1 PF01522.16 ETS78712.1 - 3.4e-20 71.9 0.0 7.5e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 ETS78712.1 - 0.032 12.2 0.0 0.054 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) ABC2_membrane PF01061.19 ETS78713.1 - 3.2e-93 310.7 57.3 6.4e-48 162.6 15.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 ETS78713.1 - 3.4e-35 119.7 6.8 3.2e-32 110.2 0.2 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 ETS78713.1 - 8.1e-35 120.1 0.0 3.9e-16 59.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 ETS78713.1 - 9.1e-21 73.7 0.0 2.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS78713.1 - 1e-08 34.8 0.0 9.7e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS78713.1 - 1.7e-07 31.4 0.2 1.7e-05 24.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETS78713.1 - 1.1e-05 24.7 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS78713.1 - 0.00012 21.9 0.0 0.071 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 ETS78713.1 - 0.0003 19.9 14.5 0.0003 19.9 10.0 3.4 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 ETS78713.1 - 0.0003 20.2 0.2 0.024 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 ETS78713.1 - 0.00034 20.1 0.2 0.0033 16.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 ETS78713.1 - 0.0016 17.7 0.0 1.3 8.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 ETS78713.1 - 0.0019 19.0 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS78713.1 - 0.0026 17.8 0.2 0.74 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS78713.1 - 0.011 16.0 0.0 0.78 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 ETS78713.1 - 0.013 15.5 0.0 0.93 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 ETS78713.1 - 0.016 14.9 0.0 3.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 ETS78713.1 - 0.019 14.6 0.1 2 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETS78713.1 - 0.023 14.3 0.1 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETS78713.1 - 0.024 14.8 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETS78713.1 - 0.027 14.0 0.1 0.63 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS78713.1 - 0.04 13.8 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS78713.1 - 0.14 12.5 0.0 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS78713.1 - 0.35 10.2 0.9 24 4.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Zn_clus PF00172.13 ETS78714.1 - 7.2e-08 32.2 18.9 7.2e-08 32.2 13.1 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpB7 PF09486.5 ETS78714.1 - 0.1 12.5 0.2 0.1 12.5 0.1 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ank_2 PF12796.2 ETS78716.1 - 7.8e-32 109.4 0.3 1.1e-13 51.3 0.2 4.9 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78716.1 - 2.2e-26 90.2 2.2 1.6e-05 24.4 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 ETS78716.1 - 1.1e-20 71.5 0.3 3.4e-05 23.6 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 ETS78716.1 - 4.8e-17 61.9 0.4 0.00018 21.9 0.0 5.7 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS78716.1 - 2.3e-13 49.8 0.1 0.0051 17.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) p450 PF00067.17 ETS78717.1 - 7.8e-37 126.8 0.0 9.6e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF3_p135 PF12807.2 ETS78717.1 - 0.12 12.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Jiraiya PF15038.1 ETS78717.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Jiraiya DUF1993 PF09351.5 ETS78718.1 - 5.3e-40 136.9 0.0 6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) COesterase PF00135.23 ETS78719.1 - 1.7e-102 343.8 0.1 2.3e-102 343.4 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78719.1 - 5.6e-05 22.8 0.2 0.00081 19.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS78719.1 - 0.0056 15.9 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family GPI-anchored PF10342.4 ETS78720.1 - 1.7e-17 63.7 1.7 1.7e-17 63.7 1.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 ETS78720.1 - 0.0094 15.4 1.4 0.013 15.0 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Med24_N PF11277.3 ETS78720.1 - 0.71 7.2 3.3 0.89 6.9 2.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal RAP1 PF07218.6 ETS78720.1 - 1.3 7.0 11.8 1.5 6.8 8.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_C97 PF05903.9 ETS78721.1 - 1.1e-06 28.4 0.4 1.7e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 ETS78721.1 - 8.8e-05 22.4 3.5 0.00048 20.0 2.4 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Ctr PF04145.10 ETS78721.1 - 0.035 14.1 0.5 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family GSCFA PF08885.6 ETS78721.1 - 0.22 11.0 1.9 0.25 10.8 0.3 1.7 1 1 1 2 2 2 0 GSCFA family DIOX_N PF14226.1 ETS78722.1 - 1.4e-18 67.4 0.0 2.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS78722.1 - 6.6e-16 58.4 0.0 1.3e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS78723.1 - 4.4e-26 91.4 38.0 4.4e-26 91.4 26.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS78723.1 - 0.0002 21.3 0.7 0.0002 21.3 0.5 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF1228) Ank_2 PF12796.2 ETS78724.1 - 2.6e-108 354.5 3.2 6e-25 87.4 0.1 8.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78724.1 - 6e-95 306.6 5.7 1.1e-07 31.2 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 ETS78724.1 - 2.1e-74 237.9 4.8 3.3e-06 26.8 0.0 15.3 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 ETS78724.1 - 1.2e-69 229.5 5.7 4.5e-11 42.9 0.1 11.8 2 2 7 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS78724.1 - 4.6e-66 217.3 8.9 6e-08 32.6 0.0 12.8 2 2 12 14 14 14 13 Ankyrin repeats (many copies) NACHT PF05729.7 ETS78724.1 - 2.7e-08 33.6 0.0 9e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Shigella_OspC PF06128.6 ETS78724.1 - 1.3e-05 24.8 1.5 0.091 12.2 0.0 4.7 4 1 1 5 5 5 2 Shigella flexneri OspC protein AAA_16 PF13191.1 ETS78724.1 - 0.00017 21.6 0.5 0.00086 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS78724.1 - 0.095 12.8 0.4 0.82 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain COesterase PF00135.23 ETS78725.1 - 3.3e-12 45.9 3.4 1.2e-11 44.0 2.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78725.1 - 3.8e-12 46.2 0.0 4.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS78725.1 - 1.1e-08 34.9 0.1 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS78725.1 - 4.7e-05 23.3 0.4 8.1e-05 22.6 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS78725.1 - 0.028 13.0 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) FMN_dh PF01070.13 ETS78726.1 - 1.1e-99 333.7 0.0 1.5e-99 333.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS78726.1 - 3e-24 84.6 0.0 5.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS78726.1 - 3.5e-05 22.8 0.1 5.7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS78726.1 - 6.1e-05 22.0 1.2 0.00014 20.9 0.4 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS78726.1 - 0.00019 20.7 0.2 0.00032 19.9 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 ETS78726.1 - 0.023 13.6 0.1 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 ETS78726.1 - 0.079 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Fungal_trans PF04082.13 ETS78727.1 - 2.5e-08 33.1 0.0 4.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78727.1 - 8.7e-05 22.3 11.6 0.00014 21.7 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 ETS78728.1 - 8.3e-62 209.0 0.0 1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS78728.1 - 3.2e-32 111.7 0.0 5.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS78728.1 - 3.3e-06 26.2 4.0 0.017 14.0 0.2 2.6 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 ETS78728.1 - 1.8e-05 24.7 0.6 6e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS78728.1 - 0.00012 21.1 2.1 0.0048 15.8 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS78728.1 - 0.00024 21.2 0.1 0.083 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS78728.1 - 0.0028 17.5 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS78728.1 - 0.0041 16.2 0.1 0.014 14.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 ETS78728.1 - 0.0048 15.4 0.1 0.021 13.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS78728.1 - 0.0084 15.0 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 ETS78728.1 - 0.087 13.2 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPDase PF07823.6 ETS78729.1 - 1.8e-35 122.2 0.0 2e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 ETS78729.1 - 0.0018 18.0 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF336 PF03928.9 ETS78730.1 - 1.7e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Baculo_PEP_C PF04513.7 ETS78731.1 - 2.4e-05 24.1 12.9 0.018 14.8 0.9 3.0 1 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETS78731.1 - 0.018 14.2 5.4 0.088 11.9 0.6 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein BMC PF00936.14 ETS78731.1 - 0.076 12.7 3.8 0.063 12.9 1.0 2.1 2 0 0 2 2 2 0 BMC domain FlaC_arch PF05377.6 ETS78731.1 - 0.59 10.0 3.8 1.3 8.9 0.1 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Ank_2 PF12796.2 ETS78732.1 - 1e-13 51.3 0.2 3e-05 24.2 0.0 3.9 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78732.1 - 3.9e-10 39.0 0.5 0.022 14.5 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 ETS78732.1 - 2e-08 34.4 0.8 0.024 15.1 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78732.1 - 3.8e-07 29.7 0.6 1.5 9.3 0.0 4.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 ETS78732.1 - 7.3e-07 29.2 1.3 0.22 11.8 0.0 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) COesterase PF00135.23 ETS78733.1 - 1.8e-70 238.1 0.0 2.4e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78733.1 - 1.9e-07 30.8 1.9 2.2e-06 27.3 0.1 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS78733.1 - 0.13 12.0 1.2 0.26 11.0 0.8 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS78733.1 - 0.17 10.4 0.0 9.2 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) MOSC_N PF03476.11 ETS78736.1 - 3.9e-17 62.0 0.1 8.3e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS78736.1 - 9.3e-16 57.5 0.2 1.3e-14 53.8 0.1 2.2 1 1 0 1 1 1 1 MOSC domain Glyco_hydro_3 PF00933.16 ETS78737.1 - 2.3e-59 200.8 0.0 3.3e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS78737.1 - 7.7e-46 156.4 0.1 1.3e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 ETS78737.1 - 1e-18 67.0 13.6 2.4e-18 65.8 9.5 1.7 1 0 0 1 1 1 1 WSC domain Fn3-like PF14310.1 ETS78737.1 - 6.1e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_63 PF03200.11 ETS78738.1 - 5.9e-08 31.0 5.9 9.7e-07 27.0 0.1 3.4 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase CorA PF01544.13 ETS78739.1 - 8.4e-06 25.0 1.2 8.4e-06 25.0 0.8 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 ETS78739.1 - 0.26 9.8 0.7 0.45 9.0 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RasGEF PF00617.14 ETS78741.1 - 1.2e-45 155.6 2.3 3.5e-45 154.0 0.6 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 ETS78741.1 - 6.9e-14 51.8 0.3 2.6e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 ETS78741.1 - 3.9e-13 49.9 0.0 2.3e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 ETS78741.1 - 3e-07 29.9 0.0 1.6e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.13 ETS78741.1 - 0.016 14.6 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 ETS78741.1 - 0.018 15.1 0.0 0.61 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain SCF PF02404.10 ETS78741.1 - 0.034 13.3 1.6 0.79 8.8 0.2 2.2 2 0 0 2 2 2 0 Stem cell factor AAA_21 PF13304.1 ETS78741.1 - 0.14 12.1 0.3 0.72 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain OSCP PF00213.13 ETS78742.1 - 8.6e-44 149.4 2.3 1.1e-43 149.0 1.6 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2293 PF10056.4 ETS78743.1 - 1.3e-24 85.9 0.0 5.4e-24 83.9 0.0 2.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Snf7 PF03357.16 ETS78744.1 - 1.1e-35 122.4 9.5 1.4e-35 122.2 6.6 1.1 1 0 0 1 1 1 1 Snf7 AAA PF00004.24 ETS78745.1 - 4.1e-89 295.5 0.0 1.3e-46 158.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS78745.1 - 2.7e-12 46.6 0.0 1.8e-05 24.5 0.0 3.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS78745.1 - 3.6e-12 46.6 0.1 0.00012 22.1 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 ETS78745.1 - 5.6e-12 45.9 0.1 0.00077 19.6 0.0 4.6 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 ETS78745.1 - 1.2e-11 44.0 0.0 0.00014 21.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS78745.1 - 3.2e-11 44.1 0.2 0.00025 21.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 ETS78745.1 - 1.8e-10 40.5 2.8 0.01 15.2 0.0 4.6 2 2 1 4 4 4 3 AAA domain AAA_33 PF13671.1 ETS78745.1 - 1e-09 38.4 0.0 0.0012 18.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 ETS78745.1 - 1.4e-09 37.8 0.0 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 ETS78745.1 - 3e-09 37.0 0.0 0.0018 18.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 ETS78745.1 - 4.3e-09 36.0 0.0 0.0034 16.8 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 ETS78745.1 - 9.4e-09 34.9 0.0 0.0021 17.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 ETS78745.1 - 1.8e-08 34.5 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 ETS78745.1 - 3.8e-08 32.6 0.0 0.001 18.1 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin NACHT PF05729.7 ETS78745.1 - 5.6e-08 32.6 0.1 0.021 14.4 0.0 3.7 2 2 2 4 4 3 2 NACHT domain AAA_28 PF13521.1 ETS78745.1 - 6e-08 32.8 0.0 0.0037 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 ETS78745.1 - 2.1e-07 30.3 0.2 0.0056 15.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS78745.1 - 2.2e-06 28.0 0.0 0.081 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 ETS78745.1 - 5.3e-06 26.3 0.3 0.058 13.0 0.0 3.6 3 2 0 3 3 2 2 Archaeal ATPase ABC_tran PF00005.22 ETS78745.1 - 1.8e-05 25.0 0.0 0.41 10.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter TIP49 PF06068.8 ETS78745.1 - 3.5e-05 22.6 0.0 0.13 10.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Cytidylate_kin2 PF13189.1 ETS78745.1 - 5.7e-05 23.0 0.0 0.098 12.5 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family UPF0079 PF02367.12 ETS78745.1 - 7.4e-05 22.3 0.0 0.073 12.7 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 ETS78745.1 - 0.00016 20.8 0.0 0.16 11.0 0.0 2.9 3 0 0 3 3 3 1 KaiC AAA_3 PF07726.6 ETS78745.1 - 0.0002 20.9 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.11 ETS78745.1 - 0.00026 19.9 0.0 0.07 11.9 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase PhoH PF02562.11 ETS78745.1 - 0.00027 20.2 0.1 0.6 9.3 0.0 2.6 3 0 0 3 3 2 2 PhoH-like protein AAA_24 PF13479.1 ETS78745.1 - 0.00028 20.5 0.2 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DAP3 PF10236.4 ETS78745.1 - 0.00036 19.5 0.0 4.6 6.0 0.0 3.2 2 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 ETS78745.1 - 0.00037 20.0 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 ETS78745.1 - 0.00037 19.4 0.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 ETS78745.1 - 0.00051 20.0 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 ETS78745.1 - 0.00069 18.6 0.0 0.23 10.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 ETS78745.1 - 0.00071 18.3 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 ETS78745.1 - 0.00078 18.3 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.17 ETS78745.1 - 0.0011 18.8 0.0 0.55 10.0 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.13 ETS78745.1 - 0.0014 18.2 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 ETS78745.1 - 0.0028 17.4 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 1 NTPase Sigma54_activat PF00158.21 ETS78745.1 - 0.0032 16.9 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 ETS78745.1 - 0.0055 16.3 0.0 2.4 7.7 0.0 3.3 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_23 PF13476.1 ETS78745.1 - 0.007 16.7 0.5 0.23 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain ResIII PF04851.10 ETS78745.1 - 0.015 15.1 0.0 1.6 8.5 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETS78745.1 - 0.016 14.7 0.0 7 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RBM1CTR PF08081.6 ETS78745.1 - 0.023 14.3 0.0 0.087 12.5 0.0 2.0 1 0 0 1 1 1 0 RBM1CTR (NUC064) family SRPRB PF09439.5 ETS78745.1 - 0.046 12.9 0.2 6.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.16 ETS78745.1 - 0.056 12.8 0.6 15 4.9 0.0 4.1 3 2 1 5 5 4 0 Guanylate kinase PduV-EutP PF10662.4 ETS78745.1 - 0.059 12.8 0.0 7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 ETS78745.1 - 0.071 12.0 0.4 9.7 5.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 ETS78745.1 - 0.073 12.4 4.2 4.7 6.5 0.1 3.9 4 1 1 5 5 4 0 AAA-like domain cobW PF02492.14 ETS78745.1 - 0.15 11.4 0.6 19 4.6 0.0 3.0 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP PF05804.7 ETS78745.1 - 0.21 9.4 0.0 0.33 8.8 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Lactonase PF10282.4 ETS78746.1 - 1.7e-08 33.9 1.7 9.8e-05 21.5 0.1 3.8 3 1 1 4 4 4 3 Lactonase, 7-bladed beta-propeller NHL PF01436.16 ETS78746.1 - 0.00069 19.4 0.2 8.8 6.5 0.0 4.3 4 0 0 4 4 4 2 NHL repeat NUDIX PF00293.23 ETS78748.1 - 1e-18 67.2 0.4 1.2e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.10 ETS78749.1 - 2.4e-41 140.7 0.2 3.9e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 ETS78749.1 - 2.1e-14 53.0 0.5 4.4e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 ETS78749.1 - 0.01 15.8 3.3 0.02 14.8 0.1 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 ETS78750.1 - 3.4e-13 49.8 2.5 9.6e-13 48.3 1.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS78750.1 - 0.00026 20.7 0.5 0.00047 19.8 0.4 1.5 1 0 0 1 1 1 1 KR domain DUF1479 PF07350.7 ETS78750.1 - 0.028 12.9 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) adh_short_C2 PF13561.1 ETS78750.1 - 0.04 13.6 0.0 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 ETS78750.1 - 0.043 13.3 2.4 0.068 12.7 0.5 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 ETS78750.1 - 0.083 12.8 1.2 0.75 9.7 0.7 2.0 1 1 1 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 ETS78750.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNase_PH PF01138.16 ETS78751.1 - 1.8e-14 54.1 0.2 3.7e-13 49.9 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS78751.1 - 0.0066 16.3 0.2 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HC2 PF07382.6 ETS78752.1 - 0.0084 15.9 32.7 0.0084 15.9 22.7 2.0 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Cytochrom_C PF00034.16 ETS78753.1 - 3.1e-09 37.5 0.0 4.7e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 ETS78753.1 - 2.7e-08 33.8 1.5 1.5e-07 31.4 1.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 ETS78753.1 - 0.00046 19.6 0.2 0.011 15.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 ETS78753.1 - 0.044 14.0 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C1 PF02167.10 ETS78753.1 - 0.078 12.6 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Rifin_STEVOR PF02009.11 ETS78754.1 - 0.024 14.2 16.7 0.064 12.8 11.6 1.6 1 1 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 ETS78754.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 ETS78754.1 - 0.045 13.2 0.2 0.099 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ATP-synt_B PF00430.13 ETS78754.1 - 0.078 12.7 30.9 0.82 9.4 13.7 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF769 PF05590.6 ETS78754.1 - 0.097 11.8 4.7 0.16 11.1 3.3 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DUF2207 PF09972.4 ETS78754.1 - 0.12 10.9 0.1 0.35 9.4 0.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3948 PF13134.1 ETS78754.1 - 0.13 11.7 0.8 0.4 10.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Adeno_E3_CR2 PF02439.10 ETS78754.1 - 0.17 11.4 2.1 0.37 10.3 1.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2359 PF10151.4 ETS78754.1 - 0.25 9.8 7.0 0.39 9.2 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF3584 PF12128.3 ETS78754.1 - 0.28 8.4 16.6 0.38 8.0 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Plasmodium_Vir PF05795.6 ETS78754.1 - 0.31 10.1 3.8 0.11 11.6 0.7 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Cluap1 PF10234.4 ETS78754.1 - 4.8 6.3 14.7 7.6 5.6 10.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Prominin PF05478.6 ETS78754.1 - 6.9 4.0 11.2 9.5 3.6 7.8 1.1 1 0 0 1 1 1 0 Prominin Peptidase_M56 PF05569.6 ETS78754.1 - 9.4 5.1 11.1 0.088 11.7 1.4 1.9 1 1 0 2 2 2 0 BlaR1 peptidase M56 LSM PF01423.17 ETS78755.1 - 6.3e-13 48.0 0.0 1.3e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 LSM domain Acetyltransf_1 PF00583.19 ETS78756.1 - 2.4e-14 53.1 0.1 4.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS78756.1 - 3e-09 37.0 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS78756.1 - 2e-07 31.0 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS78756.1 - 4.5e-07 29.5 0.0 9.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 ETS78756.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 ETS78756.1 - 0.00068 19.5 0.0 0.0009 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS78756.1 - 0.0086 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SURF2 PF05477.6 ETS78758.1 - 0.032 13.3 0.4 0.054 12.6 0.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Mob1_phocein PF03637.12 ETS78759.1 - 3.3e-69 232.0 0.0 4.2e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mito_carr PF00153.22 ETS78760.1 - 5.9e-46 154.1 7.3 3.1e-18 65.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4633 PF15464.1 ETS78760.1 - 0.011 15.6 1.6 0.018 14.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Apt1 PF10351.4 ETS78760.1 - 0.85 8.3 4.9 1.4 7.6 3.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Actino_peptide PF14408.1 ETS78760.1 - 5.3 7.0 11.3 8.6 6.3 7.1 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Pex14_N PF04695.8 ETS78760.1 - 6.3 6.8 11.9 1.8 8.6 5.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Complex1_LYR PF05347.10 ETS78761.1 - 7.7e-10 38.4 0.6 1.2e-09 37.8 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS78761.1 - 0.0038 17.3 4.9 0.006 16.7 3.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 ETS78762.1 - 2.4e-26 91.3 1.0 2.4e-26 91.3 0.7 3.5 4 2 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 ETS78762.1 - 1e-13 51.2 17.9 1e-13 51.2 12.4 4.4 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 ETS78762.1 - 1.4e-06 28.0 14.4 1.4e-06 28.0 10.0 5.1 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS78762.1 - 4.1e-06 26.7 11.9 4.1e-06 26.7 8.2 5.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS78762.1 - 1.8e-05 24.2 11.6 1.8e-05 24.2 8.0 5.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS78762.1 - 0.0017 18.0 12.2 0.0017 18.0 8.4 6.6 3 3 2 5 5 5 1 zinc-RING finger domain Cwf_Cwc_15 PF04889.7 ETS78762.1 - 1.3 8.6 9.1 3 7.5 6.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.8 ETS78762.1 - 4.9 6.9 12.7 0.69 9.7 4.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.2 ETS78763.1 - 1.6e-56 188.5 11.8 8.3e-15 54.9 0.0 5.0 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SPX PF03105.14 ETS78763.1 - 8.1e-29 101.2 14.6 4.5e-16 59.4 4.1 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 ETS78763.1 - 4e-27 94.0 5.6 8.6e-09 35.6 0.4 6.4 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 ETS78763.1 - 5e-26 89.1 12.8 1.2e-05 24.8 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 ETS78763.1 - 2e-19 69.1 12.6 2.2e-05 24.5 0.0 8.0 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78763.1 - 1.9e-17 61.6 11.5 0.0063 16.6 0.0 8.0 9 0 0 9 9 9 4 Ankyrin repeat GDPD PF03009.12 ETS78763.1 - 8.9e-08 31.9 0.0 1e-06 28.4 0.0 2.6 2 2 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.1 ETS78763.1 - 0.093 12.0 2.9 0.94 8.8 0.1 2.9 2 0 0 2 2 2 0 Ribosome-assembly protein 3 Coa1 PF08695.5 ETS78765.1 - 7.4e-40 135.0 0.0 9.3e-40 134.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 ETS78766.1 - 5.2e-31 108.0 3.0 3.3e-30 105.3 2.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 DUF814 PF05670.8 ETS78767.1 - 6.6e-17 61.1 0.0 1.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Microcephalin PF12258.3 ETS78767.1 - 0.076 11.9 0.7 0.089 11.7 0.5 1.1 1 0 0 1 1 1 0 Microcephalin protein PITH PF06201.8 ETS78768.1 - 8.6e-48 161.9 0.0 1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 ETS78768.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Rrn6 PF10214.4 ETS78769.1 - 1e-53 182.6 0.0 1.2e-52 179.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 ETS78770.1 - 1.2e-22 79.6 0.1 4e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 ETS78770.1 - 0.00071 18.3 6.8 0.0012 17.6 4.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein THOC7 PF05615.8 ETS78770.1 - 0.0052 17.0 6.7 0.0052 17.0 4.6 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 DUF2353 PF09789.4 ETS78770.1 - 0.0078 15.5 10.5 0.013 14.7 7.3 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CagE_TrbE_VirB PF03135.9 ETS78770.1 - 0.092 12.5 8.1 3.3 7.4 2.5 2.3 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system V_ATPase_I PF01496.14 ETS78770.1 - 0.17 9.6 5.7 0.22 9.3 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 ETS78770.1 - 0.28 10.0 12.5 0.57 9.0 8.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 ETS78770.1 - 0.6 10.4 12.3 0.43 10.8 7.2 1.6 2 0 0 2 2 2 0 AAA domain Striatin PF08232.7 ETS78770.1 - 0.67 10.2 18.0 0.026 14.8 5.9 2.3 1 1 1 2 2 2 0 Striatin family COG2 PF06148.6 ETS78770.1 - 0.82 9.5 9.3 14 5.5 4.4 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF342 PF03961.8 ETS78770.1 - 1.1 7.5 11.6 1.8 6.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2570 PF10828.3 ETS78770.1 - 1.2 8.7 14.2 2.2 7.9 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Mnd1 PF03962.10 ETS78770.1 - 1.4 8.5 18.3 1.6 8.3 4.2 2.3 1 1 1 2 2 2 0 Mnd1 family FUSC PF04632.7 ETS78770.1 - 1.6 7.0 3.4 1.9 6.8 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 ETS78770.1 - 2.9 7.4 15.8 1 8.9 9.0 1.7 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 ETS78770.1 - 3.9 5.8 16.7 27 3.0 11.6 2.0 1 1 0 1 1 1 0 AAA domain Med8 PF10232.4 ETS78770.1 - 5 6.5 13.5 45 3.4 0.0 2.2 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF4140 PF13600.1 ETS78770.1 - 8.8 6.8 11.9 2.6 8.5 5.3 2.4 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) MOZART1 PF12554.3 ETS78771.1 - 8.6e-25 85.9 0.5 1e-24 85.7 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CUE PF02845.11 ETS78772.1 - 4.7e-13 48.3 0.0 8e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 ETS78773.1 - 7.6e-23 80.5 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS78773.1 - 3.1e-22 78.5 0.2 8.3e-22 77.1 0.1 1.7 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS78773.1 - 5.2e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS78773.1 - 2.2e-05 24.6 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS78773.1 - 0.00026 20.1 0.2 0.022 13.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 ETS78773.1 - 0.00043 19.8 1.9 0.001 18.6 0.4 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 ETS78773.1 - 0.0043 15.9 0.7 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 ETS78773.1 - 0.01 15.4 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS78773.1 - 0.018 14.9 0.1 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS78773.1 - 0.032 14.5 0.9 0.28 11.4 0.1 2.8 3 1 0 4 4 4 0 ABC transporter SRP54 PF00448.17 ETS78773.1 - 0.039 13.3 0.3 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 ETS78773.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 ETS78773.1 - 0.093 12.1 0.2 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 ETS78773.1 - 0.1 12.9 0.1 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS78773.1 - 0.1 12.3 0.8 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain Endomucin PF07010.7 ETS78774.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Endomucin SKG6 PF08693.5 ETS78775.1 - 2.5e-07 29.8 2.1 1e-06 27.9 1.5 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ABA_WDS PF02496.11 ETS78775.1 - 0.09 12.9 0.2 4.6 7.4 0.0 2.4 1 1 1 2 2 2 0 ABA/WDS induced protein CcmD PF04995.9 ETS78775.1 - 0.24 11.1 1.0 0.43 10.3 0.7 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rifin_STEVOR PF02009.11 ETS78775.1 - 0.57 9.7 7.4 7.9 6.0 5.1 2.1 1 1 0 1 1 1 0 Rifin/stevor family Macoilin PF09726.4 ETS78775.1 - 3.4 5.8 18.3 3.4 5.8 12.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1741 PF08427.5 ETS78776.1 - 7.6e-87 290.6 0.4 4.3e-86 288.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 ETS78777.1 - 3.2e-19 68.9 0.0 4.2e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2360 PF10152.4 ETS78777.1 - 1.7 8.9 6.1 2.3 8.4 4.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 ETS78777.1 - 3.1 7.1 18.2 3.9 6.7 12.6 1.1 1 0 0 1 1 1 0 Vta1 like TerY-C PF15616.1 ETS78778.1 - 2.9 7.8 8.9 8.6 6.3 0.3 2.9 2 1 0 2 2 2 0 TerY-C metal binding domain Pyr_redox_2 PF07992.9 ETS78779.1 - 2.4e-22 79.8 0.0 8.3e-22 78.0 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS78779.1 - 1.7e-11 44.3 0.1 1.3e-07 31.9 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS78779.1 - 9e-05 22.6 0.5 2.9 7.8 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS78779.1 - 0.00032 20.6 0.1 0.17 11.9 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS78779.1 - 0.00063 18.7 0.5 0.62 8.8 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 ETS78779.1 - 0.013 15.7 0.0 0.11 12.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 ETS78779.1 - 0.07 12.1 0.9 0.32 9.9 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS78779.1 - 0.14 11.5 1.5 10 5.4 0.0 3.0 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AA_permease_2 PF13520.1 ETS78780.1 - 2.8e-53 180.9 56.3 3.4e-53 180.7 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS78780.1 - 6.8e-26 90.6 41.1 9.2e-26 90.2 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3578 PF12102.3 ETS78780.1 - 0.031 13.9 0.1 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) Ank_2 PF12796.2 ETS78781.1 - 7.6e-45 151.1 3.9 2.6e-09 37.3 0.1 7.8 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78781.1 - 2.3e-24 83.9 13.8 0.023 14.4 0.0 13.0 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.1 ETS78781.1 - 2.9e-22 78.6 6.7 0.0066 16.9 0.0 10.5 6 2 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78781.1 - 4.2e-22 76.0 8.4 0.021 15.0 0.0 12.6 12 1 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 ETS78781.1 - 3.7e-16 58.7 6.6 0.54 10.5 0.0 10.4 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS78781.1 - 7.9e-08 32.0 0.1 4e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain DUF1308 PF07000.6 ETS78782.1 - 8.9e-50 169.3 0.0 5.6e-49 166.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Glyco_transf_41 PF13844.1 ETS78782.1 - 0.028 12.3 0.0 0.044 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 GMC_oxred_N PF00732.14 ETS78784.1 - 1.3e-26 93.4 0.1 4e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS78784.1 - 4.9e-22 78.7 0.4 9.9e-22 77.7 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS78784.1 - 1.9e-09 36.9 0.6 1.8e-06 27.0 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS78784.1 - 4.1e-08 32.5 0.4 3.6e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS78784.1 - 1.7e-06 28.0 0.1 0.00043 20.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS78784.1 - 3e-06 26.5 0.4 7.8e-06 25.2 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS78784.1 - 7.6e-06 25.2 0.9 1.9e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS78784.1 - 9.9e-06 25.7 0.2 0.016 15.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS78784.1 - 1.2e-05 23.9 1.5 3e-05 22.6 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS78784.1 - 2.3e-05 24.2 0.3 8.9e-05 22.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS78784.1 - 4.9e-05 22.5 0.1 0.00011 21.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 ETS78784.1 - 0.00013 20.9 0.1 0.00025 20.0 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 ETS78784.1 - 0.0016 17.3 0.1 0.0044 15.9 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 ETS78784.1 - 0.0047 15.6 1.1 0.0076 14.9 0.7 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 ETS78784.1 - 0.014 15.7 0.7 0.014 15.7 0.5 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.16 ETS78785.1 - 6.2e-16 58.2 0.0 2.7e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 ETS78786.1 - 5.5e-28 97.6 25.9 7.5e-28 97.2 18.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1352 PF07086.7 ETS78786.1 - 0.37 10.3 8.5 1.5 8.4 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) DUF1228 PF06779.9 ETS78786.1 - 1.4 9.0 6.9 0.16 11.9 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) COesterase PF00135.23 ETS78787.1 - 1.4e-75 255.0 0.0 1.8e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78787.1 - 3.4e-05 23.5 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Bac_rhamnosid PF05592.6 ETS78788.1 - 2.6e-23 82.0 0.1 3.1e-12 45.4 0.0 3.2 2 1 1 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS78788.1 - 0.0013 17.4 0.1 0.0035 16.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF608 UPF0697 PF15117.1 ETS78789.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 Cytomega_TRL10 PF06084.6 ETS78789.1 - 0.053 13.3 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Fungal_trans PF04082.13 ETS78790.1 - 2.4e-12 46.3 0.1 5.5e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78790.1 - 3.6e-08 33.1 11.9 1.2e-07 31.5 8.2 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 ETS78791.1 - 1.8e-87 291.9 52.7 1.4e-48 164.8 12.7 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS78791.1 - 3.2e-37 127.8 0.0 1.9e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS78791.1 - 7.8e-29 99.3 3.0 7.2e-26 89.8 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 ETS78791.1 - 2e-13 50.0 33.2 1.6e-08 34.0 11.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 ETS78791.1 - 7.9e-07 28.6 0.1 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 ETS78791.1 - 9.5e-06 25.6 0.0 3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 ETS78791.1 - 5.4e-05 23.3 0.0 0.019 15.1 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 ETS78791.1 - 0.00017 21.5 0.4 0.049 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETS78791.1 - 0.00069 18.8 0.1 0.0038 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETS78791.1 - 0.0011 19.2 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS78791.1 - 0.0016 17.9 0.8 0.077 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 ETS78791.1 - 0.0021 17.5 0.6 0.29 10.5 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 ETS78791.1 - 0.0028 17.6 1.0 0.29 11.0 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS78791.1 - 0.0058 17.4 0.0 1.3 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS78791.1 - 0.015 15.1 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS78791.1 - 0.031 14.0 0.3 9.7 6.0 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 ETS78791.1 - 0.041 12.7 0.1 0.48 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 ETS78791.1 - 0.062 12.7 0.4 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 ETS78791.1 - 0.082 12.8 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF3952 PF13130.1 ETS78791.1 - 0.087 12.8 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) NACHT PF05729.7 ETS78791.1 - 0.12 12.0 0.7 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 ETS78791.1 - 0.23 11.1 0.0 29 4.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase MgsA_C PF12002.3 ETS78793.1 - 4.2e-59 198.9 0.0 8.2e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 ETS78793.1 - 1.1e-13 51.4 0.1 2.3e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS78793.1 - 1e-09 37.7 0.0 2.4e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 ETS78793.1 - 5.1e-06 26.0 0.1 4.7e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 ETS78793.1 - 1.5e-05 24.7 0.1 9.8e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS78793.1 - 5.6e-05 22.3 0.1 0.11 11.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 ETS78793.1 - 6.2e-05 22.6 0.1 0.0002 21.0 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 ETS78793.1 - 0.00016 21.8 0.3 0.00088 19.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETS78793.1 - 0.00033 19.6 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETS78793.1 - 0.00034 20.6 1.2 0.032 14.2 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain DNA_pol3_delta2 PF13177.1 ETS78793.1 - 0.00045 19.9 0.0 0.015 14.9 0.0 2.4 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 ETS78793.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETS78793.1 - 0.002 17.7 0.0 0.0077 15.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 ETS78793.1 - 0.0034 16.1 0.0 0.01 14.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus CPT PF07931.7 ETS78793.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 ETS78793.1 - 0.017 14.9 0.8 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 ETS78793.1 - 0.047 14.5 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 ETS78793.1 - 0.049 13.9 0.1 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 ETS78793.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_2 PF07724.9 ETS78793.1 - 0.063 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 ETS78793.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS78793.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Rad17 PF03215.10 ETS78793.1 - 0.14 10.8 0.0 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Utp12 PF04003.7 ETS78794.1 - 1e-21 76.9 0.0 1.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 ETS78795.1 - 1.3e-29 101.8 0.1 9.1e-17 60.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BRCA-2_helical PF09169.5 ETS78798.1 - 0.00052 19.6 0.3 0.0082 15.7 0.2 2.1 2 0 0 2 2 2 1 BRCA2, helical DUF1992 PF09350.5 ETS78799.1 - 1.1e-25 89.1 0.3 3e-25 87.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) AcetylCoA_hydro PF02550.10 ETS78800.1 - 5.6e-45 153.5 0.0 9e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 ETS78800.1 - 3.4e-39 133.9 0.0 5.3e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 ETS78801.1 - 6.4e-17 61.2 33.2 6.4e-17 61.2 23.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS78801.1 - 3.5e-07 29.8 7.6 3.5e-07 29.8 5.3 2.7 4 1 1 5 5 5 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 ETS78801.1 - 0.00013 20.6 12.3 0.00013 20.6 8.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter RasGEF PF00617.14 ETS78802.1 - 9.1e-56 188.5 0.0 1.7e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS78802.1 - 4.2e-18 65.3 0.0 1.5e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 ETS78802.1 - 5.4e-06 25.8 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS78802.1 - 0.00014 21.1 0.0 0.00031 20.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF1924 PF09086.6 ETS78802.1 - 0.082 12.9 0.5 0.53 10.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) Jacalin PF01419.12 ETS78803.1 - 0.0009 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Sulfatase PF00884.18 ETS78804.1 - 6.3e-53 179.9 2.4 8.2e-53 179.5 1.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS78804.1 - 5.4e-06 25.9 0.2 8.7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase YscK PF06578.7 ETS78804.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) HET PF06985.6 ETS78806.1 - 8.2e-22 77.8 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.1 ETS78807.1 - 2.1e-50 171.5 47.6 2.6e-50 171.2 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS78807.1 - 8.4e-23 80.4 37.9 1.1e-22 80.0 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF647 PF04884.9 ETS78808.1 - 2.5e-100 334.8 0.5 3.1e-100 334.5 0.3 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.12 ETS78809.1 - 8e-87 291.0 7.2 7.5e-84 281.3 0.4 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase HET PF06985.6 ETS78810.1 - 9.2e-23 80.9 0.0 2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) peroxidase PF00141.18 ETS78811.1 - 2e-22 79.8 0.3 3.2e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 Peroxidase SNF2_N PF00176.18 ETS78812.1 - 6e-60 202.5 0.0 8.5e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETS78812.1 - 4.6e-09 36.0 0.0 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78812.1 - 1.5e-08 34.4 0.2 6.7e-08 32.2 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS78812.1 - 0.00018 21.4 0.0 0.00089 19.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 ETS78812.1 - 0.019 14.6 9.3 0.041 13.6 6.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain TgMIC1 PF11476.3 ETS78812.1 - 0.056 12.9 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 GAGA PF09237.6 ETS78812.1 - 0.12 11.9 1.2 0.35 10.4 0.8 1.7 1 0 0 1 1 1 0 GAGA factor zf-C3HC4 PF00097.20 ETS78812.1 - 1.8 8.2 9.6 4.6 6.9 6.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS78812.1 - 2.4 8.2 10.4 2.8 8.0 5.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.7 ETS78813.1 - 1.6e-10 40.9 0.1 5.2e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.1 ETS78813.1 - 4.3e-08 33.0 14.1 1.4e-06 28.2 0.1 4.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS78813.1 - 1.3e-07 31.4 27.5 0.0033 17.6 3.2 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger AAA_16 PF13191.1 ETS78813.1 - 4.4e-06 26.7 2.0 1.1e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain zf-C2H2_jaz PF12171.3 ETS78813.1 - 6.8e-06 26.0 7.5 0.08 13.1 1.4 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS78813.1 - 4.6e-05 23.4 5.5 0.22 11.8 1.8 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type AAA_33 PF13671.1 ETS78813.1 - 0.0027 17.5 0.1 0.048 13.5 0.1 2.8 1 1 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 ETS78813.1 - 0.0034 17.6 30.3 0.0038 17.4 3.5 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type NB-ARC PF00931.17 ETS78813.1 - 0.011 14.5 0.0 0.061 12.1 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 ETS78813.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-C2H2_6 PF13912.1 ETS78813.1 - 1.1 9.3 6.8 6.2 6.8 2.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger WSC PF01822.14 ETS78814.1 - 2.5e-12 46.5 3.5 2.5e-12 46.5 2.4 2.1 2 0 0 2 2 2 1 WSC domain HflK_N PF12221.3 ETS78814.1 - 2.6 7.8 4.2 5 6.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial membrane protein N terminal LysM PF01476.15 ETS78817.1 - 2.3e-16 59.3 0.0 1.7e-06 27.7 0.0 4.0 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 ETS78817.1 - 0.00059 19.7 2.0 0.00059 19.7 1.4 3.5 3 0 0 3 3 3 1 Chitin recognition protein Glyco_hydro_18 PF00704.23 ETS78818.1 - 4.2e-45 154.7 1.9 5.7e-45 154.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Shisa PF13908.1 ETS78818.1 - 1 9.5 8.6 1.9 8.6 6.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator adh_short PF00106.20 ETS78820.1 - 8.3e-23 81.1 1.9 1.1e-22 80.7 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS78820.1 - 5.7e-11 42.6 2.0 7.5e-11 42.2 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 ETS78820.1 - 1.2e-06 27.8 0.0 2.6e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS78820.1 - 4.9e-06 26.6 0.0 7.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 ETS78820.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 ETS78820.1 - 0.0084 15.7 1.0 0.019 14.5 0.8 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 ETS78820.1 - 0.0088 14.9 0.1 0.14 10.9 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 ETS78820.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 ETS78820.1 - 0.048 12.9 0.0 0.094 11.9 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 ETS78820.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 ETS78820.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS78820.1 - 0.084 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAE PF03283.8 ETS78820.1 - 0.13 10.8 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Fungal_trans_2 PF11951.3 ETS78821.1 - 1.4e-45 155.5 3.9 2.3e-45 154.8 2.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78821.1 - 5.6e-07 29.3 7.1 1.1e-06 28.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BBE PF08031.7 ETS78822.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 ETS78822.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain DUF3328 PF11807.3 ETS78823.1 - 2.5e-44 151.5 0.8 3.3e-44 151.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.1 ETS78825.1 - 1.7e-15 57.0 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS78825.1 - 6.6e-13 48.9 0.0 1.8e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS78825.1 - 4.3e-12 46.3 0.0 8.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78825.1 - 5.7e-12 45.4 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78825.1 - 6.4e-09 36.3 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS78825.1 - 3.9e-06 25.7 0.0 4.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 ETS78825.1 - 0.0011 18.3 0.1 0.002 17.5 0.1 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 ETS78825.1 - 0.0014 18.6 0.0 0.0045 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS78825.1 - 0.0035 17.6 0.0 0.0085 16.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS78825.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 ETS78825.1 - 0.022 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.12 ETS78825.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Arylsulfotran_2 PF14269.1 ETS78826.1 - 5.9e-61 206.2 0.8 9.4e-61 205.5 0.6 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) adh_short_C2 PF13561.1 ETS78827.1 - 1.6e-17 64.0 0.0 2.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS78827.1 - 2.8e-16 59.8 0.0 4.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS78827.1 - 3.1e-08 33.5 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS78827.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 ETS78828.1 - 1.3e-44 152.3 0.1 1.4e-42 145.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS78828.1 - 8e-06 24.8 0.2 9.8e-06 24.5 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS78828.1 - 1.3e-05 24.4 0.1 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS78828.1 - 0.0011 18.6 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS78828.1 - 0.02 14.1 0.1 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 ETS78828.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ank PF00023.25 ETS78829.1 - 1e-132 425.8 29.5 2.1e-10 39.8 0.0 17.9 17 1 1 18 18 18 15 Ankyrin repeat Ank_2 PF12796.2 ETS78829.1 - 2e-129 422.2 9.9 1.8e-21 76.2 0.0 9.2 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS78829.1 - 3.4e-112 365.0 30.6 4.8e-12 46.0 0.0 14.4 3 2 13 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78829.1 - 2.1e-96 306.0 12.2 1e-06 28.4 0.0 18.5 18 0 0 18 18 18 13 Ankyrin repeat Ank_5 PF13857.1 ETS78829.1 - 3.9e-93 303.3 42.3 2.1e-12 46.8 0.1 16.2 4 1 12 16 16 16 15 Ankyrin repeats (many copies) HeLo PF14479.1 ETS78829.1 - 9.4e-25 87.6 0.0 3.3e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 ETS78829.1 - 2.9e-13 49.7 0.0 6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Orn_Arg_deC_N PF02784.11 ETS78829.1 - 0.0018 17.4 0.1 7.1 5.7 0.0 4.3 4 1 1 5 5 5 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Nitro_FeMo-Co PF02579.12 ETS78829.1 - 0.022 14.7 0.1 18 5.4 0.0 4.7 5 1 2 7 7 7 0 Dinitrogenase iron-molybdenum cofactor AAA_16 PF13191.1 ETS78829.1 - 0.03 14.3 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 ETS78829.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DmpG_comm PF07836.6 ETS78829.1 - 0.18 11.2 0.0 0.46 9.9 0.0 1.6 1 0 0 1 1 1 0 DmpG-like communication domain DUF445 PF04286.7 ETS78829.1 - 0.3 10.5 1.0 11 5.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF445) DUF1110 PF06533.7 ETS78829.1 - 0.55 10.0 16.2 31 4.3 0.1 8.2 7 3 1 9 9 9 0 Protein of unknown function (DUF1110) WD40 PF00400.27 ETS78830.1 - 2.6e-69 226.8 8.2 1.3e-11 43.9 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat HET PF06985.6 ETS78830.1 - 3.2e-21 75.9 3.1 2.3e-20 73.1 2.1 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) eIF2A PF08662.6 ETS78830.1 - 1.8e-11 44.1 0.0 2.4e-06 27.3 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 ETS78830.1 - 1.3e-08 34.7 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS78830.1 - 3.2e-06 27.2 0.2 9.9e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain BBS2_Mid PF14783.1 ETS78830.1 - 4.4e-05 23.2 0.0 0.059 13.1 0.0 3.4 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.4 ETS78830.1 - 0.00071 18.8 0.3 17 4.8 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 ETS78830.1 - 0.0012 18.4 0.8 1e+02 2.7 0.0 5.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 ETS78830.1 - 0.003 16.6 0.3 0.029 13.3 0.0 2.1 1 1 0 2 2 2 1 KAP family P-loop domain PQQ_2 PF13360.1 ETS78830.1 - 0.0043 16.5 0.1 1.6 8.1 0.0 2.4 1 1 0 2 2 2 2 PQQ-like domain AAA_22 PF13401.1 ETS78830.1 - 0.0045 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.11 ETS78830.1 - 0.0063 14.8 0.1 0.096 10.9 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain DUF815 PF05673.8 ETS78830.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ETS78830.1 - 0.056 13.6 0.3 0.87 9.7 0.0 3.2 3 1 0 3 3 2 0 RNA helicase Arch_ATPase PF01637.13 ETS78830.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Thymidylate_kin PF02223.12 ETS78830.1 - 0.13 11.6 0.0 0.36 10.1 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase Nucleoporin_N PF08801.6 ETS78830.1 - 0.26 9.9 2.1 2 7.0 0.7 2.6 1 1 0 2 2 2 0 Nup133 N terminal like FAD_binding_3 PF01494.14 ETS78831.1 - 1.1e-10 41.1 0.4 3e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS78831.1 - 0.00019 21.3 0.0 0.00026 20.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS78831.1 - 0.0005 20.0 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS78831.1 - 0.00097 18.0 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS78831.1 - 0.002 16.6 0.0 0.0058 15.1 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS78831.1 - 0.0065 15.4 0.0 0.01 14.7 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS78831.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 ETS78831.1 - 0.039 12.8 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS78831.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS78831.1 - 0.14 12.2 0.1 0.91 9.5 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tub_2 PF04525.7 ETS78832.1 - 2.7e-10 39.9 0.4 6.5e-10 38.7 0.3 1.6 1 1 0 1 1 1 1 Tubby C 2 Lactonase PF10282.4 ETS78833.1 - 2.3e-64 217.6 0.1 2.8e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS78833.1 - 0.0038 16.6 0.0 0.023 14.0 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region DUF1900 PF08954.6 ETS78833.1 - 0.043 13.3 0.0 10 5.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1900) Erf4 PF10256.4 ETS78834.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Peptidase_S49_N PF08496.5 ETS78834.1 - 1.5 8.6 4.9 2.4 7.9 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DAO PF01266.19 ETS78835.1 - 4.5e-29 101.4 0.1 5.3e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS78835.1 - 4e-06 26.7 0.0 1.4e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS78835.1 - 1.9e-05 23.7 0.0 4e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 ETS78835.1 - 0.00022 20.3 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS78835.1 - 0.00024 21.0 0.0 0.0028 17.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS78835.1 - 0.00084 19.5 0.0 0.0027 17.9 0.0 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.22 ETS78835.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS78835.1 - 0.0037 16.3 0.0 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 ETS78835.1 - 0.0046 17.0 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS78835.1 - 0.014 14.2 0.0 0.044 12.6 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 ETS78835.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS78835.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 ETS78835.1 - 0.14 10.6 0.0 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.17 ETS78836.1 - 3.4e-84 283.0 0.0 3.9e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HPP PF04982.8 ETS78837.1 - 2.3e-39 133.9 7.4 3.8e-39 133.2 5.1 1.3 1 0 0 1 1 1 1 HPP family ABC_membrane PF00664.18 ETS78837.1 - 0.86 8.9 4.3 1.9 7.8 0.3 2.3 3 0 0 3 3 3 0 ABC transporter transmembrane region DUF3712 PF12505.3 ETS78838.1 - 1.9e-11 44.0 0.5 1.7e-08 34.5 0.2 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 ETS78838.1 - 3.9e-07 30.3 1.2 11 6.4 0.1 5.8 5 0 0 5 5 5 3 Late embryogenesis abundant protein ESSS PF10183.4 ETS78838.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF974 PF06159.8 ETS78839.1 - 2.3e-79 266.3 0.0 3.4e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun PF07919.7 ETS78839.1 - 0.00018 20.0 0.0 0.00021 19.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi DENN PF02141.16 ETS78840.1 - 1.3e-57 194.5 0.5 2.2e-57 193.7 0.0 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 ETS78840.1 - 9.1e-18 63.9 0.3 2.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 ETS78840.1 - 5e-17 61.7 0.5 1.2e-16 60.5 0.3 1.6 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 ETS78840.1 - 0.036 13.7 7.1 0.07 12.8 4.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 ETS78840.1 - 0.12 12.4 3.3 0.28 11.2 2.3 1.7 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 ETS78840.1 - 0.17 12.0 4.2 0.34 11.0 2.9 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 ETS78840.1 - 0.64 9.7 8.5 1.5 8.5 5.9 1.6 1 0 0 1 1 1 0 PHD-finger PPI_Ypi1 PF07491.6 ETS78841.1 - 5.4e-24 83.5 0.0 5.4e-24 83.5 0.0 2.5 1 1 1 2 2 2 1 Protein phosphatase inhibitor MTBP_C PF14920.1 ETS78841.1 - 0.043 13.3 5.7 0.05 13.1 4.0 1.2 1 0 0 1 1 1 0 MDM2-binding GRP PF07172.6 ETS78841.1 - 3.9 8.0 11.3 7.9 7.0 7.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family CCP_MauG PF03150.9 ETS78842.1 - 0.0061 16.8 0.2 0.0071 16.6 0.1 1.0 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Aldo_ket_red PF00248.16 ETS78843.1 - 4.6e-56 189.7 0.0 5.3e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.9 ETS78846.1 - 0.15 11.0 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase Tannase PF07519.6 ETS78847.1 - 4.6e-65 220.1 0.1 1.4e-64 218.5 0.1 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase HET PF06985.6 ETS78848.1 - 2.3e-33 115.2 0.2 4.3e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.3 ETS78849.1 - 1e-34 120.1 1.7 2.9e-34 118.6 0.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Methyltransf_11 PF08241.7 ETS78851.1 - 4.7e-06 27.0 0.0 7.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS78851.1 - 8.3e-06 26.2 0.0 1.3e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS78851.1 - 8.1e-05 22.9 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78851.1 - 0.00063 19.3 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 ETS78851.1 - 0.0075 15.4 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 ETS78851.1 - 0.048 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 ETS78851.1 - 0.067 12.1 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF791 PF05631.9 ETS78852.1 - 2.1e-44 151.6 5.5 2.6e-44 151.3 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 ETS78852.1 - 3.1e-10 39.3 13.8 6.4e-10 38.2 3.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78852.1 - 3.9e-06 25.7 6.3 6.6e-06 24.9 4.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 ETS78852.1 - 0.0089 15.7 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 MFS_1 like family ketoacyl-synt PF00109.21 ETS78853.1 - 6.8e-64 215.7 0.0 1.7e-63 214.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS78853.1 - 2.9e-55 186.7 0.1 7e-55 185.4 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS78853.1 - 4e-51 173.9 0.0 6.3e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 ETS78853.1 - 9e-51 173.0 0.0 1.7e-50 172.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS78853.1 - 1.7e-43 148.4 1.9 3.2e-43 147.5 0.0 2.6 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS78853.1 - 1.7e-36 124.6 0.0 4.4e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS78853.1 - 3.3e-13 49.3 0.1 1.1e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS78853.1 - 7e-13 49.5 0.0 4.1e-12 47.1 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 ETS78853.1 - 6.2e-05 22.1 0.1 0.00015 20.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 ETS78853.1 - 7e-05 22.5 0.4 0.00018 21.2 0.0 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS78853.1 - 0.0034 17.6 0.2 0.011 15.9 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 ETS78853.1 - 0.018 14.7 0.2 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1233 PF06806.7 ETS78853.1 - 0.17 11.4 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative excisionase (DUF1233) p450 PF00067.17 ETS78855.1 - 3e-66 223.8 0.0 3.9e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 ETS78856.1 - 1.4e-27 95.7 2.4 2.9e-27 94.7 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RTA1 PF04479.8 ETS78857.1 - 1.8e-35 122.4 10.5 3.5e-35 121.5 7.3 1.4 1 0 0 1 1 1 1 RTA1 like protein DUF4173 PF13777.1 ETS78857.1 - 0.39 9.9 11.8 1.2 8.3 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF420 PF04238.7 ETS78857.1 - 0.48 10.3 18.4 0.57 10.1 6.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF420) DUF373 PF04123.8 ETS78857.1 - 2.4 7.0 10.7 1.3 7.9 5.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF2976 PF11190.3 ETS78857.1 - 2.8 7.5 9.3 0.7 9.4 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) L51_S25_CI-B8 PF05047.11 ETS78859.1 - 1.2e-19 69.7 0.0 2.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.18 ETS78860.1 - 2.8e-06 27.2 0.0 2e-05 24.4 0.0 2.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase C2 PF00168.25 ETS78861.1 - 1.7e-21 75.8 0.0 2.4e-14 52.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain IMS PF00817.15 ETS78863.1 - 5.1e-39 133.4 0.0 8.9e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS78863.1 - 4.9e-10 39.4 0.3 1.1e-09 38.2 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DNA_RNApol_7kD PF03604.8 ETS78863.1 - 0.0075 15.7 0.2 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit IMS_HHH PF11798.3 ETS78863.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif DLH PF01738.13 ETS78864.1 - 9e-24 83.9 0.0 1.4e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS78864.1 - 5.4e-07 29.4 0.0 7.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS78864.1 - 0.00065 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 ETS78864.1 - 0.0014 18.5 0.1 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 ETS78864.1 - 0.0022 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 ETS78864.1 - 0.034 12.6 0.0 0.084 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) HSP70 PF00012.15 ETS78865.1 - 1.2e-269 895.3 4.1 1.4e-269 895.1 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS78865.1 - 1.6e-15 56.5 0.1 1.7e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 ETS78865.1 - 0.0053 16.4 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 ETS78865.1 - 0.011 14.9 0.1 0.033 13.3 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PMBR PF09373.5 ETS78865.1 - 0.34 10.9 0.1 0.34 10.9 0.0 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat FtsA PF14450.1 ETS78865.1 - 0.51 10.1 3.3 17 5.2 2.3 3.0 1 1 0 1 1 1 0 Cell division protein FtsA DUF3128 PF11326.3 ETS78866.1 - 3.3e-24 84.7 0.2 8e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 ETS78867.1 - 2.1e-159 530.6 0.7 2.1e-159 530.6 0.5 1.7 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 ETS78867.1 - 1.7e-05 24.3 0.0 6.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 ETS78867.1 - 0.00013 21.7 0.1 0.0006 19.5 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase RRM_5 PF13893.1 ETS78867.1 - 0.00023 20.9 0.0 0.00062 19.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 ETS78867.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_14 PF13173.1 ETS78867.1 - 0.091 12.6 0.1 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 ETS78867.1 - 0.12 12.4 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CENP-C_C PF11699.3 ETS78868.1 - 1.5e-32 111.3 0.5 2.4e-32 110.7 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 ETS78868.1 - 3.4e-29 102.1 2.3 3.4e-29 102.1 1.6 5.0 1 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 ETS78868.1 - 1.6e-05 24.2 0.0 4.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain DUF1153 PF06627.6 ETS78868.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) RNase_HII PF01351.13 ETS78869.1 - 1.7e-44 151.8 0.0 2.1e-39 135.2 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII RHD3 PF05879.7 ETS78870.1 - 0 1050.6 0.0 0 1050.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 ETS78870.1 - 5.9e-08 32.0 0.1 9.9e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 ETS78870.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 ETS78870.1 - 2.6e-05 24.1 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 ETS78870.1 - 0.00049 20.1 0.0 0.0036 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETS78870.1 - 0.0012 19.3 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Cys_Met_Meta_PP PF01053.15 ETS78870.1 - 0.014 13.6 0.1 0.023 13.0 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme NUC173 PF08161.7 ETS78870.1 - 0.095 12.0 0.1 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 NUC173 domain HlyIII PF03006.15 ETS78871.1 - 9e-53 178.9 16.6 1.1e-52 178.6 11.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related ESSS PF10183.4 ETS78871.1 - 0.016 15.6 0.6 11 6.4 0.1 2.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MBOAT_2 PF13813.1 ETS78871.1 - 0.94 9.6 5.4 1.5 8.9 0.5 2.8 2 1 0 3 3 3 0 Membrane bound O-acyl transferase family DUF975 PF06161.6 ETS78871.1 - 1.5 8.5 8.0 0.16 11.7 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF975) TFIID_30kDa PF03540.8 ETS78872.1 - 1.1e-25 89.2 0.3 1.6e-25 88.6 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 ETS78872.1 - 0.053 13.9 0.4 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.16 ETS78873.1 - 4e-23 80.8 0.0 5.9e-23 80.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 GMC_oxred_N PF00732.14 ETS78874.1 - 3.7e-55 187.1 0.0 4.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS78874.1 - 1e-33 116.6 0.0 2e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS78874.1 - 8.8e-05 21.5 0.0 0.0005 19.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 ETS78874.1 - 9.1e-05 21.5 0.2 0.0011 17.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS78874.1 - 0.00017 21.5 0.0 0.00054 19.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS78874.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 ETS78874.1 - 0.045 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS78874.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS78874.1 - 0.05 12.6 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 ETS78874.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS78874.1 - 0.14 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein LicD PF04991.8 ETS78875.1 - 6.2e-38 130.9 4.4 1.5e-36 126.4 3.0 2.1 1 1 0 1 1 1 1 LicD family WLM PF08325.5 ETS78876.1 - 2.7e-47 161.0 0.0 4.8e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 ETS78876.1 - 0.00023 21.0 2.7 0.00035 20.4 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.18 ETS78876.1 - 0.0068 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Peptidase_MA_2 PF13485.1 ETS78876.1 - 0.012 15.6 0.3 0.038 14.0 0.1 1.9 1 1 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 ETS78876.1 - 0.049 13.2 0.1 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Rad60-SLD PF11976.3 ETS78876.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ER_lumen_recept PF00810.13 ETS78877.1 - 5.5e-54 182.6 7.1 8.4e-54 182.0 4.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 ETS78877.1 - 4.2 6.9 12.3 0.23 11.0 0.2 3.7 4 1 1 5 5 5 0 PQ loop repeat Rifin_STEVOR PF02009.11 ETS78878.1 - 0.71 9.4 6.3 1.2 8.6 4.4 1.4 1 0 0 1 1 1 0 Rifin/stevor family Ribosomal_S8e PF01201.17 ETS78879.1 - 1e-46 158.3 1.7 1.2e-46 158.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 ETS78879.1 - 0.56 10.5 4.7 3.8 7.8 3.3 2.3 1 1 1 2 2 2 0 Small acidic protein family RabGAP-TBC PF00566.13 ETS78880.1 - 8.2e-45 152.8 0.0 8.2e-45 152.8 0.0 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PilJ PF13675.1 ETS78880.1 - 0.032 14.5 6.4 0.32 11.3 0.5 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HALZ PF02183.13 ETS78880.1 - 0.033 13.8 18.2 0.11 12.2 1.5 3.8 2 1 0 3 3 3 0 Homeobox associated leucine zipper Atg14 PF10186.4 ETS78880.1 - 0.75 8.6 17.6 2.3 7.1 12.2 1.9 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S21 PF00716.12 ETS78880.1 - 1.3 8.3 12.7 0.87 8.8 6.7 2.4 1 1 1 2 2 2 0 Assemblin (Peptidase family S21) ILVD_EDD PF00920.16 ETS78881.1 - 2.3e-151 504.7 0.1 2.7e-151 504.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DUF218 PF02698.12 ETS78882.1 - 6e-10 38.8 0.1 1.4e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 DUF218 domain p450 PF00067.17 ETS78883.1 - 1e-16 60.5 0.0 2.8e-09 36.0 0.0 2.5 3 0 0 3 3 3 2 Cytochrome P450 Fer2 PF00111.22 ETS78883.1 - 3.8e-10 39.3 1.2 6.6e-10 38.5 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 ETS78883.1 - 1.3e-08 35.3 0.0 0.00011 22.6 0.0 3.8 4 0 0 4 4 4 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS78883.1 - 4.7e-08 33.0 0.0 9.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.1 ETS78883.1 - 0.069 12.9 0.2 0.19 11.5 0.2 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.7 ETS78883.1 - 0.13 12.1 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pept_tRNA_hydro PF01195.14 ETS78884.1 - 1.9e-26 92.6 0.0 2.3e-25 89.1 0.0 2.2 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase AMP-binding PF00501.23 ETS78885.1 - 1.1e-78 264.5 0.0 1.9e-78 263.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS78885.1 - 2.4e-42 144.5 0.1 3.9e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 ETS78885.1 - 3e-08 34.5 0.0 7.9e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 ETS78885.1 - 1.1e-06 28.7 0.0 3.8e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 ETS78885.1 - 1.7e-06 27.6 0.0 4.3e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS78885.1 - 0.00034 20.5 0.6 0.00097 19.0 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS78885.1 - 0.031 12.9 0.5 0.053 12.2 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF607 PF04678.8 ETS78885.1 - 0.21 11.5 0.4 0.61 9.9 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function, DUF607 Aminotran_5 PF00266.14 ETS78886.1 - 1.6e-43 148.8 0.0 3.1e-43 147.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS78886.1 - 0.00024 19.5 0.0 0.00038 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TPR_12 PF13424.1 ETS78887.1 - 1e-12 47.7 4.0 1.2e-08 34.7 0.1 4.9 4 1 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 ETS78887.1 - 5.8e-08 31.9 0.0 5.7e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_10 PF13374.1 ETS78887.1 - 7.4e-07 28.8 4.7 0.081 12.8 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS78887.1 - 0.0002 21.0 0.4 0.52 10.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS78887.1 - 0.0034 16.9 0.4 0.028 14.0 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 ETS78887.1 - 0.01 15.8 2.6 0.064 13.2 0.0 3.7 3 1 0 3 3 3 0 AAA ATPase domain Apc3 PF12895.2 ETS78887.1 - 0.01 15.9 0.0 0.04 14.0 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS78887.1 - 0.067 13.5 3.2 3 8.2 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS78887.1 - 0.14 12.8 1.7 3.2 8.5 0.1 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS78887.1 - 0.16 11.8 0.0 0.91 9.4 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS78887.1 - 1.3 9.8 7.6 4.2 8.2 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_M19 PF01244.16 ETS78889.1 - 8.9e-92 307.4 0.0 1.3e-45 155.7 0.0 2.0 2 0 0 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Peptidase_C12 PF01088.16 ETS78890.1 - 1.6e-46 158.1 0.0 1.9e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 2OG-FeII_Oxy PF03171.15 ETS78891.1 - 3.4e-10 40.1 0.0 6.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_S8 PF00082.17 ETS78894.1 - 4.9e-16 58.7 0.0 1.5e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Subtilase family Ank_5 PF13857.1 ETS78894.1 - 0.00031 20.8 0.1 0.62 10.4 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS78894.1 - 0.00055 19.6 1.2 0.99 9.3 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 ETS78894.1 - 0.0024 18.1 0.0 0.078 13.3 0.0 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS78894.1 - 0.0061 16.6 0.1 29 5.2 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 ETS78896.1 - 8.7e-162 525.9 14.4 2e-18 66.5 1.3 14.9 5 4 7 14 14 14 13 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78896.1 - 7.8e-119 382.0 40.2 3.7e-06 26.4 0.0 29.2 29 1 0 29 29 29 25 Ankyrin repeat Ank_4 PF13637.1 ETS78896.1 - 6.3e-111 361.0 25.0 1.2e-07 32.0 0.0 22.4 9 4 16 25 25 25 22 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78896.1 - 1.1e-95 303.8 21.7 0.0001 22.1 0.0 29.7 29 1 1 30 30 30 20 Ankyrin repeat Ank_5 PF13857.1 ETS78896.1 - 2e-93 304.2 36.0 2.8e-05 24.1 0.0 24.3 6 4 17 26 26 26 23 Ankyrin repeats (many copies) SPRY PF00622.23 ETS78896.1 - 5e-14 52.4 0.3 1e-13 51.4 0.2 1.5 1 0 0 1 1 1 1 SPRY domain DUF3447 PF11929.3 ETS78896.1 - 6.8e-05 22.5 0.1 13 5.6 0.1 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3447) Herpes_US9 PF06072.6 ETS78897.1 - 0.063 13.1 2.6 0.95 9.3 0.1 3.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 HET PF06985.6 ETS78899.1 - 3.1e-34 118.1 2.4 5e-34 117.4 1.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAO PF01266.19 ETS78900.1 - 3.2e-41 141.4 0.0 4.7e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS78900.1 - 3.6e-05 23.5 0.2 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 ETS78900.1 - 0.00098 18.0 0.0 0.0037 16.1 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS78900.1 - 0.0027 17.6 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS78900.1 - 0.0052 15.7 0.1 0.16 10.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS78900.1 - 0.023 14.5 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS78900.1 - 0.028 14.4 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS78900.1 - 0.034 14.2 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 ETS78900.1 - 0.04 13.3 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 ETS78900.1 - 0.084 11.4 0.0 1.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AP_endonuc_2 PF01261.19 ETS78900.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ThiF PF00899.16 ETS78900.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family UDPGT PF00201.13 ETS78901.1 - 1.4e-06 27.1 0.0 8.6e-05 21.2 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS78901.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Peptidase_S15 PF02129.13 ETS78903.1 - 1.6e-37 129.4 0.7 1.1e-35 123.4 0.5 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS78903.1 - 1e-30 107.3 0.0 1.5e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS78903.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS78903.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PhyH PF05721.8 ETS78904.1 - 1.1e-07 32.0 0.1 5e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS78904.1 - 4.5e-07 28.7 0.6 0.0069 14.9 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) MFS_1 PF07690.11 ETS78905.1 - 2.2e-19 69.4 20.0 2.2e-19 69.4 13.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78905.1 - 1.9e-09 36.6 25.2 1.3e-08 33.8 17.5 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS78905.1 - 0.0011 17.2 0.9 0.0017 16.6 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Steroid_dh PF02544.11 ETS78906.1 - 1.6e-27 96.1 0.3 2.2e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 ETS78906.1 - 0.00032 20.7 0.1 0.0006 19.8 0.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETS78906.1 - 0.0063 15.8 0.3 0.0088 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GCN5L1 PF06320.8 ETS78907.1 - 1.5e-10 40.9 0.3 2.7e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) eIF3_N PF09440.5 ETS78907.1 - 0.15 12.2 0.1 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain SOG2 PF10428.4 ETS78908.1 - 8.5e-87 291.6 0.0 8.5e-87 291.6 0.0 3.3 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 ETS78908.1 - 1.5e-17 62.7 3.3 2.9e-07 29.9 0.1 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS78908.1 - 3.5e-17 61.9 2.8 7.3e-10 38.4 0.1 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 ETS78908.1 - 1.5e-09 36.5 4.4 0.28 11.3 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 ETS78908.1 - 6.5e-07 28.5 0.7 2.1 8.9 0.0 5.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 ETS78908.1 - 0.032 14.3 5.1 12 6.3 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Helicase_C PF00271.26 ETS78909.1 - 5.3e-17 61.4 0.0 1.7e-14 53.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 ETS78909.1 - 2e-16 59.9 0.0 6.3e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 ETS78909.1 - 0.028 13.2 0.1 0.047 12.4 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CorA PF01544.13 ETS78910.1 - 3.9e-07 29.3 8.1 1.4e-06 27.5 5.5 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 ETS78911.1 - 8.5e-102 333.7 22.0 5.6e-16 58.6 0.2 8.9 1 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 ETS78911.1 - 2e-75 245.0 3.5 0.0011 18.7 0.0 18.0 17 1 0 17 17 17 15 Ankyrin repeat Ank_5 PF13857.1 ETS78911.1 - 5.4e-69 226.6 12.8 1.7e-08 34.3 0.0 14.2 1 1 17 18 18 18 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS78911.1 - 1.6e-59 197.3 10.0 3.6e-08 33.7 0.0 13.7 4 2 12 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS78911.1 - 2.3e-53 172.7 0.7 0.069 13.4 0.0 18.4 18 0 0 18 18 18 13 Ankyrin repeat PNP_UDP_1 PF01048.15 ETS78911.1 - 4.3e-10 38.9 0.3 1.3e-09 37.3 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 ETS78911.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS78911.1 - 0.0056 16.8 0.6 0.052 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Pyr_redox_2 PF07992.9 ETS78912.1 - 1.1e-37 129.9 0.7 1.5e-37 129.4 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 ETS78912.1 - 1.4e-33 115.2 0.2 3e-33 114.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 ETS78912.1 - 1.9e-18 66.6 4.2 1.6e-17 63.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS78912.1 - 5.3e-11 42.9 0.0 3.9e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS78912.1 - 3.3e-05 22.5 1.8 0.83 8.0 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein K_oxygenase PF13434.1 ETS78912.1 - 9.4e-05 21.4 0.0 0.0033 16.4 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 ETS78912.1 - 0.016 14.2 0.3 0.033 13.2 0.2 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 ETS78912.1 - 0.045 12.8 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS78912.1 - 0.091 12.3 0.2 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 ETS78912.1 - 0.34 9.7 6.0 2.3 6.9 1.2 2.6 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.17 ETS78912.1 - 1.2 7.9 5.4 3.7 6.2 3.6 2.0 2 1 0 2 2 2 0 Glucose inhibited division protein A Ydc2-catalyt PF09159.5 ETS78913.1 - 1.3e-66 224.8 0.0 1.8e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 ETS78913.1 - 6.9e-05 22.7 0.0 0.79 9.5 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 ETS78913.1 - 0.00038 19.8 0.9 0.00054 19.3 0.1 1.7 2 0 0 2 2 2 1 SAP domain Pkinase PF00069.20 ETS78914.1 - 3.2e-76 255.9 0.0 2e-54 184.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS78914.1 - 2.5e-44 151.3 0.0 3.9e-36 124.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase MMR_HSR1 PF01926.18 ETS78914.1 - 7.8e-09 35.5 0.0 2.1e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kinase-like PF14531.1 ETS78914.1 - 2.1e-06 26.9 0.0 2.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like AIG1 PF04548.11 ETS78914.1 - 9.7e-05 21.5 1.0 0.00016 20.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Sds3 PF08598.6 ETS78914.1 - 0.0001 21.9 1.9 0.00017 21.1 1.4 1.4 1 0 0 1 1 1 1 Sds3-like Kdo PF06293.9 ETS78914.1 - 0.00026 20.1 0.5 0.00061 18.9 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF258 PF03193.11 ETS78914.1 - 0.001 18.3 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 OmpH PF03938.9 ETS78914.1 - 0.016 15.1 12.8 0.038 13.9 8.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.18 ETS78914.1 - 0.024 14.4 0.0 0.024 14.4 0.0 3.4 2 2 1 3 3 2 0 Dynamin family APH PF01636.18 ETS78914.1 - 0.026 14.2 1.7 0.14 11.8 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETS78914.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF342 PF03961.8 ETS78914.1 - 1.2 7.4 9.7 2.1 6.6 6.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) FtsK_SpoIIIE PF01580.13 ETS78914.1 - 1.6 8.1 5.8 9.8 5.5 3.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Vfa1 PF08432.5 ETS78914.1 - 3.5 7.6 11.0 11 5.9 7.6 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GBP_C PF02841.9 ETS78914.1 - 4.2 6.4 17.0 8.5 5.4 11.8 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Pkinase_Tyr PF07714.12 ETS78915.1 - 4.1e-05 22.7 0.0 0.0002 20.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETS78915.1 - 0.0064 15.6 0.0 0.035 13.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain 3HCDH_N PF02737.13 ETS78916.1 - 7.6e-28 97.3 0.0 1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS78916.1 - 5.2e-14 52.4 0.1 1.5e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETS78916.1 - 0.00036 20.3 0.0 0.00087 19.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS78916.1 - 0.001 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 ETS78916.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS78916.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS78916.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_1 PF00175.16 ETS78917.1 - 1.8e-31 108.9 0.0 4.8e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS78917.1 - 9.4e-29 99.4 0.0 2.1e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 ETS78917.1 - 9.6e-24 82.9 0.1 1.8e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 ETS78917.1 - 2.7e-05 24.0 0.0 0.0012 18.8 0.0 2.8 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS78917.1 - 0.0032 17.4 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 ETS78918.1 - 5.6e-73 246.0 0.0 6.9e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 ETS78919.1 - 1.6e-20 73.0 1.5 2.3e-20 72.5 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS78919.1 - 3.1e-05 23.8 9.4 8.3e-05 22.4 6.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EAP30 PF04157.11 ETS78919.1 - 0.084 12.0 1.3 0.16 11.0 0.9 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family FlxA PF14282.1 ETS78919.1 - 1.1 9.1 10.6 0.49 10.3 4.9 2.0 2 0 0 2 2 2 0 FlxA-like protein zf-Tim10_DDP PF02953.10 ETS78920.1 - 0.25 10.6 2.5 0.25 10.6 0.4 2.0 2 0 0 2 2 2 0 Tim10/DDP family zinc finger AIP3 PF03915.8 ETS78921.1 - 4.6e-160 533.1 9.5 4.6e-160 533.1 6.6 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 AAA_13 PF13166.1 ETS78921.1 - 0.0013 17.2 0.6 0.0013 17.2 0.4 2.1 2 0 0 2 2 2 1 AAA domain DUF3138 PF11336.3 ETS78921.1 - 0.014 13.6 0.2 0.025 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.7 ETS78921.1 - 0.039 14.1 0.5 0.039 14.1 0.3 4.6 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.9 ETS78921.1 - 0.045 13.1 5.9 0.026 13.9 0.4 3.1 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FliL PF03748.9 ETS78921.1 - 0.1 12.5 3.0 0.14 12.1 0.3 2.7 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL GNVR PF13807.1 ETS78921.1 - 0.11 12.2 1.0 0.25 11.1 0.1 2.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase SpaB_C PF14028.1 ETS78921.1 - 0.13 11.8 3.8 0.13 11.7 0.5 2.5 2 0 0 2 2 2 0 SpaB C-terminal domain DUF2408 PF10303.4 ETS78921.1 - 0.23 11.5 11.3 1.3 9.1 0.5 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2408) CorA PF01544.13 ETS78921.1 - 2.4 7.0 11.9 0.4 9.6 0.2 2.8 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein TraF_2 PF13729.1 ETS78921.1 - 3.1 6.5 7.3 0.79 8.4 0.3 2.9 3 1 0 3 3 3 0 F plasmid transfer operon, TraF, protein DUF1664 PF07889.7 ETS78921.1 - 6 6.6 13.3 2.7 7.8 0.7 4.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 ETS78921.1 - 7.8 6.2 13.9 1.2 8.9 0.1 4.0 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 ETS78921.1 - 8.2 6.2 10.9 7.9 6.3 0.0 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_3 PF01494.14 ETS78922.1 - 8.2e-16 57.9 0.1 1.8e-14 53.5 0.1 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS78922.1 - 2.5e-05 23.3 0.0 0.076 11.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS78922.1 - 0.00061 18.8 0.0 0.44 9.3 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 ETS78922.1 - 0.00076 18.3 0.0 0.0015 17.4 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase S_100 PF01023.14 ETS78922.1 - 0.044 13.1 0.5 0.2 11.0 0.2 1.9 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Pyr_redox PF00070.22 ETS78922.1 - 0.048 14.0 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS78922.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Attacin_C PF03769.10 ETS78922.1 - 0.13 12.3 0.1 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Attacin, C-terminal region LsmAD PF06741.8 ETS78923.1 - 2.9e-22 78.5 1.2 2.9e-22 78.5 0.9 2.4 2 0 0 2 2 2 1 LsmAD domain Lamp PF01299.12 ETS78923.1 - 3.1 6.8 8.6 9.6 5.2 6.0 1.9 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Cupin_2 PF07883.6 ETS78925.1 - 1.2e-16 59.9 0.1 2.3e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS78925.1 - 3.9e-05 23.1 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 ETS78925.1 - 0.00016 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 ETS78925.1 - 0.0003 20.4 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 ETS78925.1 - 0.00053 19.3 0.1 0.00099 18.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.9 ETS78925.1 - 0.00061 19.7 0.2 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family JmjC PF02373.17 ETS78925.1 - 0.056 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase GPI PF06560.6 ETS78925.1 - 0.095 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) EF-hand_4 PF12763.2 ETS78927.1 - 1.9e-33 114.2 0.0 1.2e-11 44.2 0.0 3.9 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 ETS78927.1 - 4.2e-08 33.2 0.0 0.012 15.6 0.0 4.7 3 1 2 5 5 5 1 EF-hand domain pair UBA PF00627.26 ETS78927.1 - 2e-06 27.4 0.0 5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.4 ETS78927.1 - 1.6e-05 23.4 14.9 1.6e-05 23.4 10.3 1.7 2 0 0 2 2 1 1 Transmembrane protein EF-hand_6 PF13405.1 ETS78927.1 - 4.1e-05 23.0 0.2 0.31 11.0 0.1 5.0 5 0 0 5 5 4 1 EF-hand domain EF-hand_1 PF00036.27 ETS78927.1 - 0.00016 20.7 3.4 8.5 5.9 0.0 5.6 7 0 0 7 7 5 0 EF hand IncA PF04156.9 ETS78927.1 - 0.00094 18.8 17.2 0.00094 18.8 11.9 2.2 1 1 1 2 2 2 2 IncA protein DUF1664 PF07889.7 ETS78927.1 - 0.0048 16.6 7.1 0.0048 16.6 4.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF3584 PF12128.3 ETS78927.1 - 0.011 13.0 32.9 0.016 12.5 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 ETS78927.1 - 0.012 13.3 22.5 0.018 12.8 15.6 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 ETS78927.1 - 0.016 14.3 33.4 0.22 10.6 8.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 ETS78927.1 - 0.016 13.6 21.0 0.029 12.8 14.5 1.3 1 0 0 1 1 1 0 AAA domain WEMBL PF05701.6 ETS78927.1 - 0.022 13.2 27.6 0.031 12.7 19.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.6 ETS78927.1 - 0.038 12.6 33.0 0.16 10.5 8.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 ETS78927.1 - 0.055 13.2 36.8 0.22 11.2 9.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 ETS78927.1 - 0.086 11.9 14.2 0.61 9.2 2.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 ETS78927.1 - 0.27 11.0 34.3 0.032 14.1 8.3 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 ETS78927.1 - 0.41 8.3 34.5 1.1 6.9 23.9 1.7 1 1 0 1 1 1 0 Myosin tail Lebercilin PF15619.1 ETS78927.1 - 0.42 10.0 33.5 0.8 9.0 23.2 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 ETS78927.1 - 0.59 9.5 32.7 0.18 11.2 9.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF869 PF05911.6 ETS78927.1 - 0.65 8.1 23.6 0.99 7.5 16.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 ETS78927.1 - 0.82 8.5 33.9 0.48 9.3 9.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 ETS78927.1 - 0.86 9.2 31.5 1.2 8.7 7.0 2.3 1 1 0 2 2 2 0 Mnd1 family FUSC PF04632.7 ETS78927.1 - 1.1 7.6 9.7 1.9 6.8 6.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 ETS78927.1 - 1.3 8.0 34.0 0.43 9.5 15.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Peptidase_S46 PF10459.4 ETS78927.1 - 1.5 7.1 17.4 2.1 6.6 12.1 1.1 1 0 0 1 1 1 0 Peptidase S46 MAD PF05557.8 ETS78927.1 - 1.5 6.8 30.0 2.1 6.3 20.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ADIP PF11559.3 ETS78927.1 - 1.7 8.5 37.6 4.5 7.1 10.7 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.6 ETS78927.1 - 2.5 7.9 36.2 1.1 9.0 10.6 2.4 1 1 1 2 2 2 0 Rabaptin-like protein DUF3450 PF11932.3 ETS78927.1 - 2.5 7.2 31.9 2.7 7.2 12.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 ETS78927.1 - 2.6 6.3 26.0 2.1 6.6 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ATG16 PF08614.6 ETS78927.1 - 2.6 7.8 35.9 3.5 7.4 18.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 ETS78927.1 - 2.8 8.0 30.2 3 7.9 7.7 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 ETS78927.1 - 3.1 7.5 31.1 4.4 7.0 8.8 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.1 ETS78927.1 - 4.1 6.8 29.9 11 5.4 5.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4047 PF13256.1 ETS78927.1 - 4.3 7.3 14.4 0.9 9.4 6.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) COG2 PF06148.6 ETS78927.1 - 7.4 6.4 18.8 1.5 8.7 4.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4239 PF14023.1 ETS78927.1 - 7.9 5.7 8.1 19 4.5 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) THOC7 PF05615.8 ETS78927.1 - 8.7 6.6 31.3 20 5.4 9.6 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 DivIC PF04977.10 ETS78927.1 - 9 5.8 36.8 0.94 9.0 5.8 4.5 1 1 3 4 4 4 0 Septum formation initiator Occludin_ELL PF07303.8 ETS78927.1 - 9.9 6.9 18.1 3.5 8.4 2.3 3.0 1 1 2 3 3 3 0 Occludin homology domain Tubulin PF00091.20 ETS78928.1 - 6.5e-70 235.3 0.0 8.9e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS78928.1 - 4.8e-48 162.3 0.0 8.3e-48 161.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETS78928.1 - 0.0023 17.3 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.4 ETS78929.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator HAMP PF00672.20 ETS78929.1 - 0.0061 16.7 0.2 0.0061 16.7 0.2 1.6 2 0 0 2 2 2 1 HAMP domain UPF0542 PF15086.1 ETS78929.1 - 0.011 15.4 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PhrC_PhrF PF11131.3 ETS78929.1 - 0.25 10.9 0.9 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Rap-phr extracellular signalling WW PF00397.21 ETS78930.1 - 2e-07 30.7 1.0 4.5e-07 29.6 0.7 1.7 1 0 0 1 1 1 1 WW domain DUF605 PF04652.11 ETS78930.1 - 0.11 11.9 36.4 7.5 5.8 25.2 2.1 1 1 0 1 1 1 0 Vta1 like DUF1680 PF07944.7 ETS78932.1 - 6.3e-18 64.3 0.4 1.1e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 ETS78932.1 - 0.00031 19.8 0.2 0.0071 15.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Transferase PF02458.10 ETS78933.1 - 1.2e-33 116.2 0.0 3.4e-32 111.4 0.0 2.4 1 1 0 1 1 1 1 Transferase family Strabismus PF06638.6 ETS78934.1 - 0.31 9.3 2.1 0.45 8.7 1.5 1.2 1 0 0 1 1 1 0 Strabismus protein Myb_DNA-binding PF00249.26 ETS78936.1 - 3.3e-05 23.8 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF629 PF04780.7 ETS78936.1 - 0.027 12.9 6.4 0.081 11.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 ETS78936.1 - 0.045 14.0 22.1 0.15 12.4 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 ETS78936.1 - 0.78 9.9 18.3 6.9 6.8 2.2 4.1 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 ETS78936.1 - 1.6 8.8 7.5 1.1 9.3 0.9 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1 PF03811.8 ETS78936.1 - 4.3 6.9 5.3 48 3.5 1.5 3.3 3 0 0 3 3 3 0 InsA N-terminal domain Fringe PF02434.11 ETS78937.1 - 3e-05 23.3 0.2 0.00056 19.2 0.2 2.1 1 1 0 1 1 1 1 Fringe-like IGFL PF14653.1 ETS78937.1 - 0.0032 17.4 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 Insulin growth factor-like family Galactosyl_T PF01762.16 ETS78937.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Galactosyltransferase PAN_3 PF08277.7 ETS78937.1 - 0.18 11.4 1.4 0.38 10.4 1.0 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 ETS78937.1 - 0.19 11.4 4.5 0.53 10.0 3.1 1.7 1 0 0 1 1 1 0 PAN domain Toxin_17 PF08086.6 ETS78937.1 - 6.7 6.8 7.7 13 5.9 3.2 2.4 2 0 0 2 2 2 0 Ergtoxin family zf-TRAF PF02176.13 ETS78938.1 - 5.6e-18 65.0 22.9 2.1e-06 28.0 1.6 3.7 1 1 2 3 3 3 3 TRAF-type zinc finger zf-RING_5 PF14634.1 ETS78938.1 - 2.7e-07 30.1 3.5 2.7e-07 30.1 2.5 3.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS78938.1 - 6.5e-06 26.0 6.7 6.5e-06 26.0 4.6 3.3 2 1 2 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS78938.1 - 2.5e-05 24.0 6.6 2.5e-05 24.0 4.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS78938.1 - 2.9e-05 23.6 4.1 2.9e-05 23.6 2.9 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS78938.1 - 3.6e-05 23.5 7.3 3.6e-05 23.5 5.1 3.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 ETS78938.1 - 6.3e-05 22.5 6.1 6.3e-05 22.5 4.3 4.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS78938.1 - 0.001 18.7 4.4 0.001 18.7 3.1 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETS78938.1 - 0.018 14.7 1.8 0.057 13.1 1.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.16 ETS78938.1 - 0.21 11.4 26.5 0.047 13.5 1.8 4.1 2 1 2 4 4 4 0 IBR domain Sina PF03145.11 ETS78938.1 - 6.1 6.4 14.3 1 8.9 1.0 3.0 1 1 2 3 3 3 0 Seven in absentia protein family Cript PF10235.4 ETS78938.1 - 9.2 6.6 10.2 2.1 8.7 2.2 2.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT AAA PF00004.24 ETS78939.1 - 4.3e-16 59.3 0.0 1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 ETS78939.1 - 0.0032 17.7 0.0 0.0094 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS78939.1 - 0.0053 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS78939.1 - 0.0084 16.1 0.1 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETS78939.1 - 0.011 15.3 0.2 0.062 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 ETS78939.1 - 0.047 13.8 0.1 0.6 10.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS78939.1 - 0.069 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 ETS78939.1 - 0.072 12.5 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 ETS78939.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS78939.1 - 0.16 11.0 3.1 0.63 9.1 0.3 2.6 2 1 0 3 3 3 0 KaiC Bromodomain PF00439.20 ETS78941.1 - 1.3e-12 47.4 0.0 3.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF2365 PF10157.4 ETS78941.1 - 0.13 12.1 0.2 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Filament PF00038.16 ETS78942.1 - 0.0011 18.4 0.7 0.0015 18.0 0.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.15 ETS78942.1 - 0.0019 17.3 2.6 0.0027 16.8 1.8 1.1 1 0 0 1 1 1 1 Tropomyosin DUF241 PF03087.9 ETS78942.1 - 0.003 17.0 1.2 0.0041 16.6 0.8 1.2 1 0 0 1 1 1 1 Arabidopsis protein of unknown function PspA_IM30 PF04012.7 ETS78942.1 - 0.0063 15.8 0.2 0.0085 15.4 0.1 1.1 1 0 0 1 1 1 1 PspA/IM30 family Tropomyosin_1 PF12718.2 ETS78942.1 - 0.0071 16.2 2.6 0.011 15.5 1.8 1.3 1 0 0 1 1 1 1 Tropomyosin like Cob_adeno_trans PF01923.13 ETS78942.1 - 0.0088 15.8 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase SlyX PF04102.7 ETS78942.1 - 0.0091 16.3 1.1 0.017 15.5 0.8 1.4 1 0 0 1 1 1 1 SlyX Spc7 PF08317.6 ETS78942.1 - 0.012 14.3 1.3 0.015 13.9 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 ETS78942.1 - 0.017 14.7 0.6 0.024 14.2 0.4 1.3 1 0 0 1 1 1 0 IncA protein Bacillus_HBL PF05791.6 ETS78942.1 - 0.018 14.4 0.8 0.026 13.8 0.5 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cluap1 PF10234.4 ETS78942.1 - 0.022 14.0 0.8 0.028 13.6 0.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc24 PF08286.6 ETS78942.1 - 0.093 12.4 1.4 0.15 11.7 1.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TraF_2 PF13729.1 ETS78942.1 - 0.094 11.4 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF3583 PF12126.3 ETS78942.1 - 0.11 11.5 2.9 0.97 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) ABC_tran_2 PF12848.2 ETS78942.1 - 0.12 12.2 1.5 0.19 11.5 1.0 1.3 1 0 0 1 1 1 0 ABC transporter DivIC PF04977.10 ETS78942.1 - 0.21 11.0 1.3 0.39 10.2 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Allexi_40kDa PF05549.6 ETS78942.1 - 0.32 10.2 1.8 0.69 9.1 1.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein XhlA PF10779.4 ETS78942.1 - 1.9 8.4 4.3 3.3 7.6 2.9 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Asp PF00026.18 ETS78943.1 - 1.8e-54 185.1 0.5 2.1e-54 184.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS78943.1 - 0.00039 20.4 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal HSP70 PF00012.15 ETS78944.1 - 1.4e-61 208.1 11.2 1.7e-59 201.2 7.7 2.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS78944.1 - 1.7e-05 23.6 0.1 0.00055 18.6 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein DUF2294 PF10057.4 ETS78944.1 - 0.00047 19.7 0.2 0.0017 17.9 0.1 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) DivIVA PF05103.8 ETS78944.1 - 0.025 14.6 0.5 0.025 14.6 0.3 3.5 4 0 0 4 4 4 0 DivIVA protein Cyt-b5 PF00173.23 ETS78946.1 - 3.2e-11 42.8 0.0 6.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_bind_like PF02298.12 ETS78947.1 - 0.00092 18.9 0.0 0.0023 17.6 0.0 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.1 ETS78947.1 - 0.0034 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 ETS78947.1 - 0.042 14.0 2.6 0.07 13.3 0.3 2.3 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family YSIRK_signal PF04650.12 ETS78947.1 - 0.58 9.7 3.7 2.8 7.5 2.6 2.3 1 0 0 1 1 1 0 YSIRK type signal peptide RAP1 PF07218.6 ETS78947.1 - 6.2 4.7 7.6 6.8 4.6 5.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CENP-X PF09415.5 ETS78948.1 - 1.1e-26 92.4 1.0 1.7e-26 91.8 0.3 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 ETS78948.1 - 0.0082 16.1 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SDA1 PF05285.7 ETS78948.1 - 0.16 11.2 3.9 0.17 11.1 2.7 1.2 1 0 0 1 1 1 0 SDA1 Co_AT_N PF12557.3 ETS78948.1 - 0.63 9.9 3.6 1.5 8.8 2.5 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Mito_carr PF00153.22 ETS78949.1 - 1.9e-65 216.6 4.9 1.7e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 ETS78950.1 - 2.9e-39 133.3 7.0 3.1e-39 133.2 4.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 ETS78950.1 - 0.0017 17.6 0.7 0.0023 17.2 0.2 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 ETS78950.1 - 0.01 15.2 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DDRGK PF09756.4 ETS78950.1 - 0.011 15.1 0.7 0.015 14.6 0.5 1.2 1 0 0 1 1 1 0 DDRGK domain Rrf2 PF02082.15 ETS78950.1 - 0.016 15.2 0.1 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 ETS78950.1 - 0.02 14.5 0.5 0.028 14.1 0.4 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 ETS78950.1 - 0.021 14.4 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.7 ETS78950.1 - 0.066 12.7 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.7 ETS78950.1 - 0.076 12.6 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain FeoC PF09012.5 ETS78950.1 - 0.088 12.5 0.6 0.22 11.2 0.1 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator Ribosomal_S7 PF00177.16 ETS78951.1 - 3.3e-41 140.3 1.0 4e-41 140.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_5 PF13444.1 ETS78952.1 - 0.00051 20.5 0.1 0.092 13.3 0.1 2.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS78952.1 - 0.00087 19.2 0.0 0.0026 17.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family SET PF00856.23 ETS78954.1 - 0.14 12.4 0.2 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 SET domain DcpS_C PF11969.3 ETS78956.1 - 6.2e-07 29.6 0.2 4.1e-05 23.7 0.1 2.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETS78956.1 - 0.014 15.8 0.0 0.063 13.8 0.0 2.2 2 0 0 2 2 2 0 HIT domain DUF3453 PF11935.3 ETS78956.1 - 0.052 12.9 0.1 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) zf-ZPR1 PF03367.8 ETS78957.1 - 0.15 11.1 0.9 0.37 9.9 0.6 1.6 1 0 0 1 1 1 0 ZPR1 zinc-finger domain KOW PF00467.24 ETS78958.1 - 1.9e-07 30.4 1.8 1.9e-07 30.4 1.2 1.8 2 0 0 2 2 2 1 KOW motif Methyltransf_23 PF13489.1 ETS78960.1 - 4.2e-16 59.0 0.0 5.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS78960.1 - 5.7e-13 49.4 0.0 1.1e-11 45.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS78960.1 - 4.5e-12 45.7 0.0 2.1e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS78960.1 - 1.9e-10 41.0 0.0 1.4e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS78960.1 - 4e-09 36.8 0.0 7.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS78960.1 - 3e-07 30.7 0.0 6.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS78960.1 - 9.3e-05 21.8 0.0 0.0011 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 ETS78960.1 - 0.00022 20.3 0.0 0.00082 18.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 ETS78960.1 - 0.00023 21.2 0.0 0.0092 16.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS78960.1 - 0.0007 18.7 0.0 0.0064 15.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 ETS78960.1 - 0.0016 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 ETS78960.1 - 0.018 14.1 0.0 0.048 12.7 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 ETS78960.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.4 ETS78960.1 - 0.054 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 ETS78960.1 - 0.13 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 ETS78960.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 ETS78960.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.14 ETS78960.1 - 0.17 11.4 0.0 0.46 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 ETS78960.1 - 0.19 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Cyt-b5 PF00173.23 ETS78961.1 - 3.4e-20 71.6 0.1 1.5e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 ETS78961.1 - 1e-07 32.3 21.7 1e-07 32.3 15.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 ETS78961.1 - 0.035 14.1 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region LrgB PF04172.11 ETS78961.1 - 0.15 11.2 0.5 2.3 7.3 0.1 2.1 2 0 0 2 2 2 0 LrgB-like family ATP_synt_I PF03899.10 ETS78961.1 - 0.38 10.9 2.7 9.7 6.4 0.2 2.2 2 0 0 2 2 2 0 ATP synthase I chain Ima1_N PF09779.4 ETS78962.1 - 6.4e-31 107.5 1.6 1.1e-30 106.8 1.1 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 ETS78962.1 - 0.25 11.1 2.2 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Alg14 PF08660.6 ETS78963.1 - 1e-41 142.7 0.0 2.7e-41 141.3 0.0 1.7 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like DUF1517 PF07466.6 ETS78963.1 - 0.033 13.2 0.3 0.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF2360 PF10152.4 ETS78963.1 - 2 8.6 8.5 3 8.1 5.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MRP-S25 PF13741.1 ETS78964.1 - 1.2e-68 231.0 7.3 2.4e-67 226.7 5.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 ETS78964.1 - 0.004 17.0 3.4 0.024 14.5 2.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 ETS78965.1 - 1.2e-13 50.8 0.0 0.00021 21.1 0.0 4.7 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 ETS78965.1 - 7.7e-11 41.3 2.5 0.016 15.4 0.0 5.8 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 ETS78965.1 - 1.5e-09 37.1 6.4 0.0023 17.8 0.0 5.5 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 ETS78965.1 - 0.005 16.2 2.8 1.3 8.5 0.0 3.7 4 1 0 4 4 4 2 PPR repeat Clr5 PF14420.1 ETS78966.1 - 6.2e-20 70.8 3.1 1.2e-19 69.8 2.2 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_8 PF13181.1 ETS78966.1 - 0.068 12.9 0.1 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat COX7C PF02935.11 ETS78967.1 - 3.5e-14 52.3 0.8 4e-14 52.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 ETS78968.1 - 5.6e-92 307.7 0.0 1e-91 306.8 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 ETS78968.1 - 5.7e-58 195.1 4.7 8.7e-58 194.5 2.1 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 ETS78968.1 - 2.4e-23 82.4 0.1 3.7e-22 78.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS78968.1 - 3.6e-08 33.1 0.0 8.5e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS78968.1 - 0.0027 17.5 0.3 0.059 13.1 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 ETS78968.1 - 0.017 13.9 0.0 0.099 11.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein HTH_11 PF08279.7 ETS78968.1 - 0.026 14.1 0.1 0.081 12.5 0.1 1.9 1 0 0 1 1 1 0 HTH domain DUF4303 PF14136.1 ETS78968.1 - 0.1 12.2 3.2 0.52 9.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Aminotran_1_2 PF00155.16 ETS78969.1 - 3.6e-72 243.3 0.0 4.2e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 ETS78969.1 - 1.6e-05 24.0 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 ETS78969.1 - 2.1e-05 23.8 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETS78969.1 - 0.0011 17.3 0.0 0.002 16.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 ETS78969.1 - 0.0079 14.9 0.0 0.024 13.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V FAD_binding_9 PF08021.6 ETS78969.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF2407_C PF13373.1 ETS78970.1 - 7.7e-32 110.1 0.0 9.9e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 ETS78970.1 - 7.9e-26 90.0 0.0 1.8e-25 88.9 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Epimerase PF01370.16 ETS78971.1 - 8e-17 61.4 0.0 1.8e-16 60.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS78971.1 - 2.1e-11 43.2 0.0 8.1e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS78971.1 - 3.3e-10 40.2 0.4 2.3e-09 37.5 0.3 2.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS78971.1 - 3.6e-10 39.0 0.0 1.6e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS78971.1 - 1.9e-05 24.6 0.3 8.4e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 ETS78971.1 - 0.00068 18.9 0.0 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 ETS78971.1 - 0.0072 16.0 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 ETS78971.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ald_Xan_dh_C2 PF02738.13 ETS78972.1 - 4.4e-194 645.8 0.0 6.2e-194 645.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 ETS78972.1 - 6.4e-49 165.6 0.0 1.3e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 ETS78972.1 - 1.6e-32 111.4 0.4 5.1e-32 109.8 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 ETS78972.1 - 3.5e-29 100.5 0.0 6.8e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 ETS78972.1 - 4.9e-28 97.4 0.0 1.1e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 ETS78972.1 - 5.7e-08 32.3 0.7 1.9e-07 30.7 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Transferase PF02458.10 ETS78973.1 - 4.7e-33 114.2 0.0 3.7e-13 48.7 0.0 3.1 3 0 0 3 3 3 3 Transferase family Nucleoplasmin PF03066.10 ETS78973.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin NmrA PF05368.8 ETS78974.1 - 1.2e-11 44.2 0.0 1.7e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS78974.1 - 3.2e-09 37.0 0.1 5.7e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS78974.1 - 0.0076 16.5 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FMN_dh PF01070.13 ETS78975.1 - 1.1e-118 396.1 0.0 1.3e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS78975.1 - 0.0013 17.6 0.1 0.0026 16.7 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS78975.1 - 0.0028 16.6 0.1 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 ETS78975.1 - 0.0041 16.3 0.2 0.0065 15.6 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS78975.1 - 0.0061 15.8 0.2 0.48 9.6 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 ETS78975.1 - 0.014 14.4 0.2 0.7 8.9 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Med18 PF09637.5 ETS78976.1 - 1.1e-25 90.6 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Med18 protein zf-C2H2_4 PF13894.1 ETS78977.1 - 1e-05 25.4 20.6 0.026 14.8 0.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS78977.1 - 0.00075 19.6 22.5 0.017 15.4 0.7 5.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS78977.1 - 0.041 14.1 0.2 0.041 14.1 0.1 4.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-CHCC PF10276.4 ETS78977.1 - 0.11 12.3 3.4 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain DSPc PF00782.15 ETS78978.1 - 2.3e-16 59.5 0.2 3.4e-06 26.6 0.2 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain IBR PF01485.16 ETS78978.1 - 0.06 13.2 3.6 2.9 7.8 1.2 2.7 2 0 0 2 2 2 0 IBR domain PTPlike_phytase PF14566.1 ETS78978.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 ETS78978.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 ETS78978.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EGF_3 PF12947.2 ETS78978.1 - 0.3 11.0 2.6 1.1 9.2 1.8 1.9 1 0 0 1 1 1 0 EGF domain Vfa1 PF08432.5 ETS78979.1 - 3.8e-43 147.6 18.3 4.3e-43 147.4 12.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.7 ETS78979.1 - 0.012 14.8 10.2 0.014 14.5 7.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CobT PF06213.7 ETS78979.1 - 0.033 13.3 15.3 0.04 13.0 10.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BTV_NS2 PF04514.7 ETS78979.1 - 0.077 11.8 9.7 0.076 11.8 6.7 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 T2SF PF00482.18 ETS78979.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CDC45 PF02724.9 ETS78979.1 - 0.15 10.0 14.2 0.17 9.8 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ctr PF04145.10 ETS78979.1 - 0.31 11.0 2.4 0.44 10.5 1.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3987 PF13148.1 ETS78979.1 - 0.33 9.4 9.6 0.38 9.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FLO_LFY PF01698.11 ETS78979.1 - 0.4 9.4 8.4 0.44 9.3 5.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 ETS78979.1 - 0.47 9.7 23.7 0.59 9.4 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 ETS78979.1 - 0.56 9.9 11.5 0.8 9.4 8.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GAGA_bind PF06217.7 ETS78979.1 - 0.58 10.0 9.2 0.61 10.0 6.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 ETS78979.1 - 0.83 9.2 23.9 1 9.0 16.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Dicty_REP PF05086.7 ETS78979.1 - 0.97 7.1 9.0 1.2 6.8 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDHD PF02862.12 ETS78979.1 - 1.1 8.9 7.1 1.3 8.7 4.9 1.1 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 ETS78979.1 - 1.7 6.2 5.5 1.9 6.0 3.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 ETS78979.1 - 2.1 7.4 6.6 2.5 7.1 4.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 ETS78979.1 - 2.2 5.9 11.5 2.5 5.7 8.0 1.0 1 0 0 1 1 1 0 Ycf1 POX PF07526.6 ETS78979.1 - 2.2 8.5 8.2 3.1 8.0 5.7 1.3 1 0 0 1 1 1 0 Associated with HOX U79_P34 PF03064.11 ETS78979.1 - 2.7 7.4 17.6 3.5 7.0 12.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RP-C_C PF11800.3 ETS78979.1 - 3 7.4 7.5 3.7 7.2 5.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 ETS78979.1 - 3.8 7.3 14.4 4.6 7.0 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3449 PF11931.3 ETS78979.1 - 4.5 6.7 12.7 6.2 6.2 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sporozoite_P67 PF05642.6 ETS78979.1 - 5.2 4.8 13.3 6.3 4.5 9.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom22 PF04281.8 ETS78979.1 - 5.8 6.4 13.2 8.7 5.8 9.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SAPS PF04499.10 ETS78979.1 - 6.2 5.3 12.7 7.7 5.0 8.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec62 PF03839.11 ETS78979.1 - 6.3 6.1 14.5 9.4 5.5 10.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.8 ETS78979.1 - 7 5.0 13.6 8.3 4.8 9.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3438 PF11920.3 ETS78979.1 - 9 5.0 6.7 11 4.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Rtt106 PF08512.7 ETS78980.1 - 1.2e-24 86.0 0.0 5.7e-24 83.9 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_10 PF15411.1 ETS78983.1 - 8e-46 154.9 0.3 1.3e-45 154.2 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 ETS78983.1 - 5.3e-32 111.1 0.0 1e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 ETS78983.1 - 4.7e-25 87.4 0.0 9.8e-25 86.4 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 ETS78983.1 - 3.9e-09 36.0 0.0 1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 ETS78983.1 - 0.11 12.7 0.4 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 PH domain WD40 PF00400.27 ETS78984.1 - 9.4e-37 123.6 18.0 4.9e-08 32.5 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 ETS78984.1 - 6.5e-13 48.1 0.8 1.8e-12 46.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS78984.1 - 2e-06 27.2 0.2 5.3e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 ETS78984.1 - 0.027 14.2 1.5 6.2 6.6 0.0 4.2 5 1 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Seadorna_VP6 PF07407.6 ETS78984.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Snf7 PF03357.16 ETS78985.1 - 6e-44 149.4 13.2 6.7e-44 149.2 9.1 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 ETS78985.1 - 0.0016 18.6 0.7 0.18 12.0 0.5 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 ETS78985.1 - 0.0051 15.3 1.7 0.0062 15.0 1.2 1.2 1 0 0 1 1 1 1 AAA domain DUF948 PF06103.6 ETS78985.1 - 0.037 13.8 1.3 5.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 ETS78985.1 - 0.075 12.6 7.0 0.32 10.5 0.3 2.3 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 ETS78985.1 - 0.11 12.2 0.4 8.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETS78985.1 - 0.17 11.0 0.6 1.1 8.4 0.2 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 ETS78985.1 - 0.34 10.8 7.7 2.6 8.0 2.9 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Sec34 PF04136.10 ETS78985.1 - 0.35 10.5 4.0 0.7 9.5 2.4 1.7 1 1 1 2 2 2 0 Sec34-like family zf-C4H2 PF10146.4 ETS78985.1 - 0.44 10.5 7.5 0.43 10.5 4.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1993 PF09351.5 ETS78985.1 - 0.46 10.3 4.7 0.66 9.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF2312 PF10073.4 ETS78985.1 - 0.72 9.2 5.7 0.92 8.9 0.2 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Mod_r PF07200.8 ETS78985.1 - 0.99 9.3 11.6 1.9 8.3 7.5 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin PF02996.12 ETS78985.1 - 2.2 7.9 10.9 32 4.2 0.2 3.7 2 1 1 3 3 3 0 Prefoldin subunit Glutaredoxin PF00462.19 ETS78985.1 - 4 7.5 4.6 0.85 9.6 0.1 2.2 3 0 0 3 3 3 0 Glutaredoxin DUF2205 PF10224.4 ETS78985.1 - 4.1 7.0 8.0 2.3 7.8 2.0 2.4 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) BLOC1_2 PF10046.4 ETS78985.1 - 6.5 6.9 8.9 22 5.2 1.8 2.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box-like PF12937.2 ETS78986.1 - 0.091 12.5 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like Frag1 PF10277.4 ETS78987.1 - 5.5e-17 61.9 17.1 6.9e-17 61.6 11.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4231 PF14015.1 ETS78987.1 - 1.5 8.8 4.1 8.5 6.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 ETS78990.1 - 4.9e-32 111.0 41.5 4.9e-32 111.0 28.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS78990.1 - 4.5e-06 25.5 45.7 1.2e-05 24.1 5.2 4.3 3 1 1 4 4 4 3 Sugar (and other) transporter ASC PF00858.19 ETS78990.1 - 0.26 9.8 0.2 0.54 8.8 0.2 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel HMGL-like PF00682.14 ETS78991.1 - 2.3e-38 132.1 0.0 9e-38 130.2 0.0 1.8 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 ETS78992.1 - 4.7e-60 202.7 0.0 6.1e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS78992.1 - 1.2e-16 61.1 0.2 2.3e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS78992.1 - 1.2e-12 47.8 1.3 2.2e-12 47.0 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 ETS78992.1 - 0.00016 21.5 0.6 0.00035 20.4 0.4 1.6 1 0 0 1 1 1 1 HAS barrel domain Aldose_epim PF01263.15 ETS78993.1 - 1e-44 152.8 0.6 1.5e-44 152.3 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Diphthamide_syn PF01866.12 ETS78994.1 - 1.1e-110 369.7 0.0 1.2e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COesterase PF00135.23 ETS78995.1 - 1.4e-79 268.2 0.0 1.8e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS78995.1 - 0.0003 20.4 0.2 0.0013 18.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS78995.1 - 0.04 13.8 0.1 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Reo_sigmaC PF04582.7 ETS78996.1 - 0.00015 21.1 6.0 0.00015 21.1 4.2 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 ETS78996.1 - 0.00029 18.7 12.3 0.00029 18.7 8.5 2.0 1 1 1 2 2 2 1 Myosin tail DUF869 PF05911.6 ETS78996.1 - 0.01 14.1 18.1 0.016 13.4 12.5 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Phage_connect_1 PF05135.8 ETS78996.1 - 0.037 14.1 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein EzrA PF06160.7 ETS78996.1 - 0.089 10.9 18.4 0.042 12.0 9.7 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA KxDL PF10241.4 ETS78996.1 - 0.16 11.8 12.3 0.2 11.6 2.1 3.1 1 1 0 2 2 2 0 Uncharacterized conserved protein AAA_13 PF13166.1 ETS78996.1 - 0.21 9.9 14.8 0.32 9.4 10.2 1.2 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.1 ETS78996.1 - 0.22 11.8 19.8 0.098 12.9 4.4 3.5 2 1 1 3 3 3 0 Snapin/Pallidin Tropomyosin_1 PF12718.2 ETS78996.1 - 0.26 11.1 25.1 0.045 13.5 12.7 2.7 1 1 2 3 3 3 0 Tropomyosin like GAS PF13851.1 ETS78996.1 - 0.27 10.3 20.5 0.044 12.9 9.7 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 ETS78996.1 - 0.3 10.1 20.5 0.33 10.0 11.6 2.4 1 1 0 1 1 1 0 Tropomyosin DUF3584 PF12128.3 ETS78996.1 - 0.42 7.8 20.7 0.6 7.3 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.3 ETS78996.1 - 0.98 8.6 21.3 0.55 9.4 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 ETS78996.1 - 1.1 7.0 8.4 1.7 6.3 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 ETS78996.1 - 1.1 7.7 3.6 1.6 7.2 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.17 ETS78996.1 - 1.3 9.0 19.2 0.11 12.5 7.2 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 ETS78996.1 - 1.9 8.0 25.1 3.7 7.1 9.2 2.4 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 ETS78996.1 - 6 5.1 8.3 1.9 6.8 2.5 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family OmpH PF03938.9 ETS78996.1 - 6.9 6.5 22.4 1.3 8.9 6.5 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LOH1CR12 PF10158.4 ETS78996.1 - 7.2 6.4 9.6 2.8 7.7 2.5 3.1 2 1 2 4 4 4 0 Tumour suppressor protein PNK3P PF08645.6 ETS78997.1 - 7.2e-57 191.2 0.0 1.1e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 ETS78997.1 - 8.2e-31 106.8 0.0 2.5e-30 105.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS78997.1 - 0.0019 17.3 0.0 0.0046 16.0 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 ETS78997.1 - 0.014 14.5 0.0 0.57 9.3 0.0 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 ETS78997.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS78997.1 - 0.017 14.6 0.0 0.056 12.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS78997.1 - 0.023 15.5 0.3 0.11 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS78997.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HET PF06985.6 ETS78998.1 - 1.5e-37 128.8 1.3 3.2e-37 127.7 0.9 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YafO_toxin PF13957.1 ETS78998.1 - 0.097 12.4 0.2 30 4.4 0.0 3.2 3 0 0 3 3 3 0 Toxin YafO, type II toxin-antitoxin system GHMP_kinases_N PF00288.21 ETS78999.1 - 1.3e-09 37.9 2.5 5e-09 36.0 1.1 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain PhoD PF09423.5 ETS79000.1 - 6.3e-158 526.0 5.0 7.3e-158 525.8 3.5 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase ADH_zinc_N PF00107.21 ETS79001.1 - 6.1e-08 32.2 0.9 2.1e-07 30.5 0.6 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS79001.1 - 5.3e-07 29.3 0.0 1.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 ETS79001.1 - 3.2e-05 23.4 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated MFS_1 PF07690.11 ETS79002.1 - 1.8e-25 89.4 33.7 1.8e-25 89.4 23.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79002.1 - 5.7e-17 61.4 24.0 8e-17 60.9 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 ETS79002.1 - 0.093 12.3 2.5 0.18 11.4 1.7 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase AAA_16 PF13191.1 ETS79004.1 - 5.6e-08 32.9 0.0 1e-06 28.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS79004.1 - 2e-07 31.2 0.0 2.5e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETS79004.1 - 0.00011 21.9 0.0 0.00064 19.4 0.0 2.3 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 ETS79004.1 - 0.0089 15.0 0.0 0.037 12.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ank PF00023.25 ETS79004.1 - 0.022 14.5 0.0 8.8 6.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat NB-ARC PF00931.17 ETS79004.1 - 0.026 13.3 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Abhydrolase_6 PF12697.2 ETS79004.1 - 0.03 14.2 0.0 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family AAA_10 PF12846.2 ETS79004.1 - 0.031 13.7 0.0 0.25 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain cobW PF02492.14 ETS79004.1 - 0.045 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF676 PF05057.9 ETS79004.1 - 0.045 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_14 PF13173.1 ETS79004.1 - 0.081 12.8 0.0 5.5 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 ETS79004.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.2 ETS79005.1 - 3e-99 325.5 5.3 1.2e-18 67.1 0.1 8.5 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79005.1 - 5.1e-88 284.8 22.7 1.9e-07 30.5 0.0 16.7 17 0 0 17 17 17 13 Ankyrin repeat Ank_4 PF13637.1 ETS79005.1 - 4.9e-65 214.8 17.1 2.8e-11 43.6 0.0 12.3 9 4 3 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79005.1 - 3.6e-58 187.6 17.3 6.3e-05 22.8 0.0 16.1 17 0 0 17 17 17 11 Ankyrin repeat Ank_5 PF13857.1 ETS79005.1 - 2.8e-55 183.1 30.6 1.1e-08 34.9 0.1 13.1 6 5 8 14 14 14 11 Ankyrin repeats (many copies) HET PF06985.6 ETS79005.1 - 5.9e-33 113.9 0.5 9.9e-33 113.2 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.6 ETS79006.1 - 5e-12 45.4 12.5 7.9e-12 44.8 8.6 1.3 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 ETS79007.1 - 1e-22 80.6 0.0 4.2e-19 68.8 0.0 2.8 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS79007.1 - 1.1e-20 74.4 0.0 2.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.14 ETS79008.1 - 3.2e-21 75.7 0.9 6.8e-11 41.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS79008.1 - 4.8e-07 29.0 3.2 0.0014 17.6 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS79008.1 - 9.7e-06 24.9 0.8 0.1 11.6 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS79008.1 - 0.00028 21.2 0.0 0.0094 16.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS79008.1 - 0.00039 20.3 0.0 0.0009 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS79008.1 - 0.0027 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS79008.1 - 0.011 14.4 0.1 0.027 13.0 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 ETS79008.1 - 0.013 14.6 0.1 0.067 12.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 ETS79008.1 - 0.018 13.9 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 ETS79008.1 - 0.022 14.3 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS79008.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.14 ETS79008.1 - 0.083 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain NAD_binding_7 PF13241.1 ETS79008.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-C2H2_2 PF12756.2 ETS79010.1 - 0.0041 17.2 0.6 0.0041 17.2 0.4 2.0 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 ETS79010.1 - 0.64 10.1 12.2 7.5 6.7 1.7 3.9 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding GFA PF04828.9 ETS79012.1 - 8.2e-15 54.5 10.3 1e-09 38.2 0.8 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 ETS79012.1 - 0.0099 15.6 0.5 4.7 7.1 0.0 2.8 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 ETS79012.1 - 2 7.7 8.6 6.8 6.0 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-SNAP50_C PF12251.3 ETS79012.1 - 9 5.6 8.4 2 7.7 2.4 2.1 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Sugar_tr PF00083.19 ETS79013.1 - 2e-78 264.0 29.9 2.4e-78 263.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79013.1 - 6.4e-29 100.7 23.6 6.4e-29 100.7 16.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS79013.1 - 0.024 14.3 6.0 0.38 10.5 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family Glyco_hydro_3 PF00933.16 ETS79014.1 - 2.2e-81 273.1 0.0 3.1e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS79014.1 - 4.1e-58 196.5 0.0 2.1e-57 194.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS79014.1 - 4.1e-15 55.4 0.0 1.6e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 ETS79014.1 - 0.0046 16.5 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain NACHT PF05729.7 ETS79015.1 - 5.3e-07 29.4 0.2 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 ETS79015.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_10 PF12846.2 ETS79015.1 - 0.013 14.9 0.0 1.4 8.2 0.0 3.1 2 1 1 3 3 3 0 AAA-like domain DUF676 PF05057.9 ETS79015.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Acetyltransf_8 PF13523.1 ETS79016.1 - 1.1e-32 113.0 0.0 1.7e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF607 PF04678.8 ETS79017.1 - 1.4e-37 129.3 0.0 1.4e-37 129.3 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function, DUF607 Hydant_A_N PF05378.8 ETS79017.1 - 0.04 13.4 0.4 0.26 10.7 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region Glyco_trans_4_4 PF13579.1 ETS79017.1 - 0.056 13.5 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Asp PF00026.18 ETS79018.1 - 1.2e-50 172.5 0.0 1.5e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS79018.1 - 1.6e-06 28.2 0.0 5.2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS79018.1 - 0.0033 17.8 0.3 2.9 8.4 0.1 2.7 2 1 0 2 2 2 2 Aspartyl protease DUF2638 PF10937.3 ETS79019.1 - 2.9e-35 121.6 0.4 3.4e-35 121.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) MCR_C PF04609.7 ETS79020.1 - 0.0019 17.0 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase operon protein C CHORD PF04968.7 ETS79020.1 - 0.89 9.8 4.6 2.9 8.2 0.2 2.4 2 0 0 2 2 2 0 CHORD Fructosamin_kin PF03881.9 ETS79021.1 - 0.0035 16.3 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF3433 PF11915.3 ETS79024.1 - 6.9e-22 77.4 13.2 9.2e-14 51.3 0.8 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) CrtC PF07143.6 ETS79025.1 - 1.7e-22 80.1 1.2 2.3e-22 79.6 0.8 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Fungal_trans PF04082.13 ETS79026.1 - 1.9e-13 49.8 2.3 3e-13 49.2 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 ETS79027.1 - 4.4e-53 180.4 0.0 6e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.5 ETS79028.1 - 8.6e-28 97.2 0.3 3.8e-21 75.5 0.0 2.4 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 ETS79028.1 - 2.6e-20 73.0 0.5 3.7e-13 49.7 0.0 2.8 1 1 1 2 2 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 ETS79028.1 - 6.2e-11 41.9 1.2 1.6e-08 34.1 0.1 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS79028.1 - 4.9e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS79029.1 - 1.8e-12 47.2 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Alpha-E PF04168.7 ETS79029.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Ank_2 PF12796.2 ETS79030.1 - 1.1e-98 323.6 16.5 7.6e-17 61.4 0.0 7.5 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79030.1 - 1.8e-93 302.0 24.0 7.9e-08 31.7 0.0 14.7 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 ETS79030.1 - 3.7e-72 237.5 21.3 1.1e-11 44.8 0.0 11.4 5 5 6 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79030.1 - 5.1e-65 208.9 17.8 9.9e-05 22.2 0.0 14.8 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 ETS79030.1 - 5.4e-62 204.4 16.0 4.8e-08 32.9 0.0 12.5 3 2 10 13 13 13 13 Ankyrin repeats (many copies) NACHT PF05729.7 ETS79030.1 - 1.1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS79030.1 - 6e-05 23.0 1.2 0.00033 20.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS79030.1 - 7.9e-05 22.7 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETS79030.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 ETS79030.1 - 0.036 13.4 0.2 0.78 9.1 0.1 2.6 1 1 1 2 2 2 0 AAA-like domain Bac_rhamnosid PF05592.6 ETS79031.1 - 1.4e-27 96.1 0.2 1.1e-18 66.7 0.3 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS79031.1 - 4e-05 22.5 2.5 6e-05 21.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 ETS79031.1 - 0.00026 19.7 3.2 0.00033 19.4 0.9 1.8 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid_N PF08531.5 ETS79032.1 - 1.7e-44 151.4 0.4 2.6e-44 150.7 0.3 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.6 ETS79032.1 - 0.0076 14.5 0.0 0.011 13.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid PF05592.6 ETS79033.1 - 6.4e-104 347.9 0.1 7.3e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS79033.1 - 0.00032 19.5 0.5 0.00084 18.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 ETS79034.1 - 1e-121 406.6 5.3 1.6e-121 406.0 3.7 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 ETS79034.1 - 6.9e-43 146.1 0.1 1.5e-42 145.0 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain CorA PF01544.13 ETS79035.1 - 3.7e-16 59.0 0.3 1.1e-15 57.4 0.2 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2793 PF10983.3 ETS79036.1 - 0.088 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) FliD_C PF07195.7 ETS79036.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF4239 PF14023.1 ETS79036.1 - 0.14 11.4 2.1 0.15 11.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Cortex-I_coil PF09304.5 ETS79036.1 - 0.32 11.0 8.3 4.4 7.4 0.2 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil Anp1 PF03452.9 ETS79036.1 - 0.38 9.8 3.2 0.15 11.2 0.4 1.6 2 0 0 2 2 2 0 Anp1 IncA PF04156.9 ETS79036.1 - 0.48 9.9 9.1 0.22 11.0 2.3 2.1 2 0 0 2 2 2 0 IncA protein HalX PF08663.5 ETS79037.1 - 0.16 11.9 1.3 0.42 10.6 0.9 1.7 1 0 0 1 1 1 0 HalX domain adh_short PF00106.20 ETS79039.1 - 3e-24 85.8 1.4 4.5e-24 85.2 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79039.1 - 7.6e-11 42.2 0.0 9.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79039.1 - 3.9e-06 26.6 1.2 7.6e-06 25.6 0.8 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS79039.1 - 8e-05 22.1 0.6 0.00096 18.6 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS79039.1 - 0.00039 20.4 0.6 0.00055 19.9 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS79039.1 - 0.0033 16.3 0.1 0.0053 15.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 ETS79039.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 ETS79040.1 - 1.7e-17 62.5 0.0 0.00035 20.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 ETS79040.1 - 4.7e-09 36.1 0.0 4.7e-09 36.1 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 ETS79040.1 - 2.1e-08 34.2 0.3 4.3e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 RRM_1 PF00076.17 ETS79041.1 - 5.1e-17 61.2 0.0 7.4e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79041.1 - 6.9e-11 41.8 0.0 1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79041.1 - 8.7e-11 41.6 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS79041.1 - 0.004 16.8 0.0 0.0089 15.7 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif B12D PF06522.6 ETS79042.1 - 1.8e-07 30.7 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 ETS79043.1 - 2.5e-19 69.0 4.7 2.9e-19 68.8 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 ETS79043.1 - 0.0081 15.5 2.0 0.01 15.2 1.2 1.5 1 1 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 ETS79043.1 - 0.023 14.5 0.8 0.061 13.2 0.6 1.7 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.21 ETS79043.1 - 0.056 12.9 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Telomere_Sde2 PF13019.1 ETS79044.1 - 2.9e-59 199.3 0.3 4e-59 198.9 0.2 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Med8 PF10232.4 ETS79044.1 - 0.15 11.5 2.8 0.23 10.9 2.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Phage_Mu_F PF04233.9 ETS79044.1 - 0.34 11.4 3.0 0.64 10.5 1.8 1.6 1 1 0 1 1 1 0 Phage Mu protein F like protein S10_plectin PF03501.10 ETS79045.1 - 5.5e-41 138.3 0.1 6.5e-41 138.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 ETS79046.1 - 2.9e-33 113.8 0.8 5.6e-33 112.9 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS79046.1 - 3.2e-14 52.6 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS79046.1 - 5.7e-05 24.0 0.0 0.0001 23.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 ETS79046.1 - 6.2e-05 22.2 0.0 0.00024 20.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 ETS79046.1 - 0.0096 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS79046.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 ETS79046.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETS79046.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family DUF2318 PF10080.4 ETS79046.1 - 0.18 11.6 0.8 19 5.0 0.2 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) adh_short PF00106.20 ETS79047.1 - 8e-18 64.8 0.2 1.2e-17 64.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79047.1 - 2.7e-07 30.5 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS79047.1 - 3.6e-06 27.0 0.0 7.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS79047.1 - 5.7e-06 26.1 0.1 8.1e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS79047.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS79047.1 - 0.0048 15.8 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain BING4CT PF08149.6 ETS79049.1 - 2.1e-39 132.9 0.0 1.5e-35 120.5 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 ETS79049.1 - 3e-07 30.0 0.0 0.00012 21.8 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Pox_VERT_large PF04441.8 ETS79049.1 - 0.12 10.4 0.1 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit DUF663 PF04950.7 ETS79050.1 - 2.3e-106 355.1 0.0 3.9e-106 354.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 ETS79050.1 - 2.2e-23 81.5 0.0 6.5e-23 80.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 ETS79050.1 - 0.09 12.2 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PSP1 PF04468.7 ETS79051.1 - 1.4e-29 101.9 0.4 2.2e-29 101.2 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region BCNT PF07572.7 ETS79051.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Bucentaur or craniofacial development Lactamase_B PF00753.22 ETS79052.1 - 4.3e-17 62.3 3.3 7e-17 61.7 2.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS79052.1 - 2.5e-06 27.1 1.4 5.6e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Nfu_N PF08712.6 ETS79053.1 - 9.3e-30 102.0 0.0 2.6e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 ETS79053.1 - 2.5e-20 72.0 0.0 4.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.11 ETS79054.1 - 0.0009 18.8 3.9 0.0013 18.2 2.7 1.3 1 0 0 1 1 1 1 HIT zinc finger cobW PF02492.14 ETS79056.1 - 2.5e-35 121.5 0.0 3.5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 ETS79056.1 - 7.6e-07 28.1 0.1 0.002 16.9 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 ETS79056.1 - 0.0084 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 ETS79056.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.18 ETS79056.1 - 0.044 13.1 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 ETS79056.1 - 0.048 13.0 0.3 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS79056.1 - 0.068 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TMEM51 PF15345.1 ETS79056.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 NACHT PF05729.7 ETS79056.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 ETS79056.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 ETS79056.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 ETS79056.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_21 PF13304.1 ETS79056.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3176 PF11374.3 ETS79057.1 - 2.2e-31 107.9 1.6 5.9e-31 106.6 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Corona_S2 PF01601.11 ETS79057.1 - 9.7 4.1 8.7 0.21 9.6 0.1 2.0 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein ADH_zinc_N PF00107.21 ETS79058.1 - 7.9e-11 41.6 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS79058.1 - 2e-09 37.1 0.4 8.7e-09 35.1 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Spc7_N PF15402.1 ETS79060.1 - 0.059 11.3 8.5 0.068 11.1 5.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 OmpH PF03938.9 ETS79060.1 - 0.13 12.2 3.7 0.15 11.9 2.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PHA_synth_III_E PF09712.5 ETS79061.1 - 0.0018 17.7 3.2 0.0021 17.4 1.6 1.6 1 1 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Fib_alpha PF08702.5 ETS79061.1 - 0.087 12.9 8.3 0.082 13.0 3.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phasin_2 PF09361.5 ETS79061.1 - 0.21 11.6 2.3 20 5.2 0.0 3.2 4 0 0 4 4 4 0 Phasin protein ApoLp-III PF07464.6 ETS79061.1 - 4.9 7.1 9.5 1.3 9.0 3.8 2.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ribosomal_L15e PF00827.12 ETS79062.1 - 1.9e-91 304.7 12.4 2.2e-91 304.5 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.14 ETS79063.1 - 1.1e-53 175.7 13.5 1.1e-07 30.8 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 ETS79064.1 - 4.4e-114 381.2 0.0 7.1e-114 380.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ETS79064.1 - 9.6e-51 171.5 0.0 1.7e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 ETS79064.1 - 2.7e-29 101.2 0.2 6.7e-29 99.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 ETS79064.1 - 1.5e-25 89.7 0.0 4.1e-25 88.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 ETS79064.1 - 7.6e-21 73.6 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 ETS79064.1 - 2.4e-20 72.1 0.1 7e-20 70.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 ETS79064.1 - 7.1e-13 48.3 0.3 2.9e-12 46.3 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Rifin_STEVOR PF02009.11 ETS79065.1 - 0.026 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF1517 PF07466.6 ETS79065.1 - 0.031 13.2 6.5 0.086 11.8 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Alpha_GJ PF03229.8 ETS79065.1 - 0.23 11.7 8.4 0.041 14.2 1.5 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J PDGLE PF13190.1 ETS79065.1 - 0.75 9.5 7.4 14 5.4 5.0 2.9 2 1 0 2 2 2 0 PDGLE domain Rad51 PF08423.6 ETS79066.1 - 8.9e-24 83.7 0.0 1.6e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 ETS79066.1 - 1.6e-11 43.9 0.0 4.5e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 ETS79066.1 - 3.6e-07 29.5 0.0 6.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 ETS79066.1 - 1.3e-05 24.4 0.0 6.3e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 ETS79066.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS79066.1 - 0.085 13.1 0.2 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Ras PF00071.17 ETS79068.1 - 3.3e-65 218.4 0.5 4e-65 218.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS79068.1 - 2.3e-21 76.4 0.0 3.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS79068.1 - 4.4e-16 58.6 0.1 5.4e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS79068.1 - 4.2e-05 22.7 0.1 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS79068.1 - 7.1e-05 22.3 0.1 0.00015 21.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS79068.1 - 0.00012 21.9 0.0 0.00028 20.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS79068.1 - 0.00083 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 ETS79068.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS79068.1 - 0.0028 17.8 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 ETS79068.1 - 0.0082 15.4 0.0 0.052 12.8 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 ETS79068.1 - 0.018 14.2 0.0 0.046 12.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS79068.1 - 0.035 14.0 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 ETS79068.1 - 0.047 13.5 0.1 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS79068.1 - 0.064 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 ETS79068.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 ETS79068.1 - 0.11 11.1 0.1 1.9 7.1 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Methyltransf_2 PF00891.13 ETS79069.1 - 1e-32 113.2 0.1 2.1e-31 109.0 0.0 2.3 2 1 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 ETS79069.1 - 0.0033 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79069.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HTH_31 PF13560.1 ETS79069.1 - 0.087 13.0 0.1 0.64 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain FMO-like PF00743.14 ETS79070.1 - 9.1e-33 113.2 0.0 6.9e-30 103.7 0.0 3.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS79070.1 - 6.8e-20 71.9 0.0 3.1e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS79070.1 - 3.1e-12 46.0 0.0 3.2e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS79070.1 - 1.3e-10 41.5 0.0 7e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS79070.1 - 3.6e-07 30.0 0.0 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS79070.1 - 4.6e-05 23.2 0.4 0.035 13.8 0.0 3.6 2 2 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS79070.1 - 7.5e-05 21.9 0.1 0.0006 18.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS79070.1 - 0.00019 21.7 1.1 0.77 10.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS79070.1 - 0.00054 18.5 1.9 0.003 16.1 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 ETS79070.1 - 0.00081 18.5 0.8 0.0076 15.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 ETS79070.1 - 0.001 18.0 0.1 0.0033 16.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ETS79070.1 - 0.0015 17.6 0.0 0.0015 17.6 0.0 1.9 3 0 0 3 3 2 1 FAD dependent oxidoreductase DAO PF01266.19 ETS79070.1 - 0.0045 15.9 0.8 0.072 11.9 0.0 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 ETS79070.1 - 0.032 14.4 0.1 5.5 7.2 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 ETS79070.1 - 0.036 12.9 0.3 5.5 5.7 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_10 PF13460.1 ETS79070.1 - 0.11 12.5 1.4 13 5.7 0.1 3.0 3 1 0 3 3 3 0 NADH(P)-binding DUF1987 PF09345.5 ETS79071.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Carn_acyltransf PF00755.15 ETS79072.1 - 6.8e-164 546.2 0.0 8.7e-149 496.3 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF572 PF04502.8 ETS79074.1 - 3.1 6.9 20.1 5.8 6.0 13.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mitofilin PF09731.4 ETS79074.1 - 9.6 4.7 23.3 15 4.0 16.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GrpE PF01025.14 ETS79075.1 - 1.2e-49 168.0 5.6 1.5e-49 167.7 3.9 1.1 1 0 0 1 1 1 1 GrpE BicD PF09730.4 ETS79075.1 - 0.00059 18.3 2.3 0.00069 18.1 1.6 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D IncA PF04156.9 ETS79075.1 - 0.18 11.3 1.9 0.24 10.9 1.3 1.2 1 0 0 1 1 1 0 IncA protein RNA_pol_A_bac PF01000.21 ETS79076.1 - 5.9e-31 106.9 0.0 8.8e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 ETS79076.1 - 7.8e-15 53.7 0.0 1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 ETS79077.1 - 6.2e-54 179.7 0.4 1e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 ETS79078.1 - 5.4e-49 166.6 0.1 5.5e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 ETS79078.1 - 3.8e-25 87.8 0.0 7e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain p450 PF00067.17 ETS79079.1 - 1.3e-39 136.0 0.0 8.1e-31 107.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Calcipressin PF04847.7 ETS79080.1 - 4e-49 166.7 0.0 5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.7 ETS79080.1 - 0.15 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family F-box PF00646.28 ETS79081.1 - 0.0022 17.6 0.1 0.0067 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS79081.1 - 0.094 12.4 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 F-box-like RFC1 PF08519.7 ETS79084.1 - 2.6e-56 189.6 0.2 7.3e-56 188.2 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 ETS79084.1 - 2.2e-14 53.3 0.0 5.2e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 ETS79084.1 - 3.7e-09 36.8 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 ETS79084.1 - 1.5e-05 23.8 0.0 4.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 ETS79084.1 - 0.00073 19.2 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS79084.1 - 0.00084 19.4 0.0 0.0054 16.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS79084.1 - 0.00092 20.0 2.6 0.0031 18.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS79084.1 - 0.0054 16.6 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 ETS79084.1 - 0.0079 15.7 0.0 0.024 14.1 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 ETS79084.1 - 0.01 15.8 0.0 0.053 13.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 ETS79084.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 ETS79084.1 - 0.022 14.6 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 ETS79084.1 - 0.046 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS79084.1 - 0.047 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 ETS79084.1 - 0.062 13.2 0.9 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 ETS79084.1 - 0.066 12.9 0.5 0.32 10.6 0.0 2.4 3 0 0 3 3 3 0 NTPase Ribosomal_L16 PF00252.13 ETS79085.1 - 2.1e-29 101.9 0.2 2.7e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 ETS79085.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family BsuPI PF12690.2 ETS79086.1 - 0.05 13.3 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Nckap1 PF09735.4 ETS79087.1 - 0.026 12.0 0.0 0.029 11.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein OAD_gamma PF04277.8 ETS79087.1 - 0.075 13.4 0.1 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.1 ETS79087.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Ribosomal_S5_C PF03719.10 ETS79088.1 - 1.5e-17 62.6 0.0 4.2e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 ETS79088.1 - 2.4e-10 39.9 0.6 6e-10 38.7 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 ETS79089.1 - 5.5e-29 99.6 0.4 6.1e-29 99.5 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 DASH_Hsk3 PF08227.6 ETS79089.1 - 0.082 13.1 0.1 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Ank_2 PF12796.2 ETS79090.1 - 0.00037 20.7 0.0 0.021 15.1 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) RhoGEF PF00621.15 ETS79090.1 - 0.0016 18.3 0.7 1.3 8.8 0.3 2.5 2 0 0 2 2 2 2 RhoGEF domain Cortex-I_coil PF09304.5 ETS79090.1 - 0.0083 16.1 0.8 0.0083 16.1 0.6 2.7 1 1 2 3 3 3 1 Cortexillin I, coiled coil Ank_3 PF13606.1 ETS79090.1 - 0.015 15.4 0.1 1.8 9.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Fib_alpha PF08702.5 ETS79090.1 - 0.57 10.3 7.6 1.6 8.8 2.9 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family COesterase PF00135.23 ETS79091.1 - 7.9e-67 226.1 2.9 1e-66 225.7 2.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS79091.1 - 7.6e-05 22.3 0.3 0.00052 19.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79091.1 - 0.00054 19.7 0.4 0.0011 18.7 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS79091.1 - 0.014 14.9 0.1 0.038 13.5 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS79091.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS79091.1 - 0.042 13.0 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Snf7 PF03357.16 ETS79092.1 - 1.8e-16 59.9 6.2 2.4e-16 59.5 4.3 1.1 1 0 0 1 1 1 1 Snf7 DUF4200 PF13863.1 ETS79092.1 - 6.7 6.6 11.1 15 5.5 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CS PF04969.11 ETS79093.1 - 2.8e-09 37.4 0.1 4.1e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 CS domain PARP PF00644.15 ETS79094.1 - 7.2e-12 45.1 0.2 1.9e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 ETS79094.1 - 2.2e-07 30.4 0.0 5.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG5 PF10392.4 ETS79095.1 - 0.00011 22.1 0.4 0.00011 22.1 0.3 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Hex_IIIa PF02455.11 ETS79096.1 - 0.14 10.8 6.7 0.17 10.5 4.6 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Sds3 PF08598.6 ETS79097.1 - 1.7e-39 135.5 7.1 2.7e-39 134.8 4.9 1.5 1 1 0 1 1 1 1 Sds3-like ALIX_LYPXL_bnd PF13949.1 ETS79097.1 - 0.057 12.3 6.4 0.093 11.6 4.4 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PCI PF01399.22 ETS79100.1 - 5.7e-20 71.5 0.4 2e-19 69.8 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 ETS79100.1 - 1e-05 24.9 2.8 0.22 11.4 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 ETS79100.1 - 0.001 18.5 0.2 0.0021 17.4 0.2 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 ETS79100.1 - 0.012 15.3 5.0 4.4 7.3 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS79100.1 - 0.035 14.0 3.4 27 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS79100.1 - 0.085 12.5 2.9 7 6.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS79100.1 - 1.1 9.9 9.3 21 5.8 0.0 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat Med2 PF11214.3 ETS79100.1 - 5.4 7.1 8.6 0.4 10.7 0.2 3.1 3 2 0 3 3 3 0 Mediator complex subunit 2 WD40 PF00400.27 ETS79101.1 - 2.2e-39 131.9 8.2 3.4e-09 36.2 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 ETS79101.1 - 1.4e-29 101.9 16.1 2.4e-29 101.1 11.2 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 ETS79101.1 - 1.4e-05 24.9 1.8 0.0002 21.1 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 ETS79101.1 - 0.00022 20.9 0.1 9.1 6.1 0.0 4.2 4 2 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 ETS79101.1 - 0.019 13.2 0.1 0.11 10.7 0.1 2.2 2 1 0 2 2 2 0 Cytochrome D1 heme domain Cupin_2 PF07883.6 ETS79102.1 - 0.0015 17.9 0.0 0.079 12.4 0.0 2.4 1 1 0 1 1 1 1 Cupin domain MFS_1 PF07690.11 ETS79103.1 - 6.6e-14 51.3 20.6 1.2e-13 50.5 14.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS79103.1 - 0.0033 17.4 4.2 0.0033 17.4 2.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) MFS_1 PF07690.11 ETS79104.1 - 0.00067 18.4 12.0 0.00067 18.4 8.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.2 ETS79104.1 - 0.0085 15.1 2.4 0.014 14.4 1.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein MFS_1_like PF12832.2 ETS79104.1 - 0.089 12.5 1.2 0.27 11.0 0.0 2.3 2 1 0 2 2 2 0 MFS_1 like family DUF3792 PF12670.2 ETS79104.1 - 1.4 8.7 16.7 0.9 9.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Candida_ALS PF05792.8 ETS79105.1 - 7.3e-05 22.8 18.9 7.3e-05 22.8 13.1 10.0 8 2 2 10 10 10 1 Candida agglutinin-like (ALS) adh_short PF00106.20 ETS79108.1 - 5.2e-27 94.7 1.2 1.1e-26 93.7 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79108.1 - 1.9e-12 47.4 0.0 2.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79108.1 - 1.3e-09 38.0 2.7 3.2e-08 33.4 1.9 2.3 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.9 ETS79108.1 - 0.025 13.0 0.1 0.19 10.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_10 PF13460.1 ETS79108.1 - 0.058 13.3 0.1 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding Pkinase PF00069.20 ETS79109.1 - 1.7e-10 40.4 0.0 8e-10 38.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79109.1 - 0.00029 19.9 0.0 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PDEase_II PF02112.10 ETS79109.1 - 0.035 13.0 0.1 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Glyco_hydro_72 PF03198.9 ETS79110.1 - 5.1e-99 331.2 0.0 8.7e-99 330.4 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 ETS79110.1 - 0.028 13.3 0.1 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 ETS79110.1 - 0.1 11.7 0.1 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Imm10 PF15562.1 ETS79111.1 - 0.088 12.5 0.6 0.088 12.5 0.4 1.7 2 0 0 2 2 2 0 Immunity protein 10 RGS PF00615.14 ETS79112.1 - 0.00046 20.2 0.1 0.0043 17.1 0.0 2.2 2 1 0 2 2 2 1 Regulator of G protein signaling domain RGS PF00615.14 ETS79114.1 - 2.2e-13 50.3 0.0 3.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ring_hydroxyl_A PF00848.14 ETS79114.1 - 0.075 12.6 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) WD40 PF00400.27 ETS79116.1 - 4.7e-43 143.5 18.5 5.2e-12 45.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 ETS79116.1 - 0.27 10.0 0.7 0.43 9.3 0.5 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Pribosyl_synth PF14572.1 ETS79117.1 - 3.7e-41 140.8 1.8 1e-35 123.1 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 ETS79117.1 - 2.3e-29 101.4 0.0 6.5e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 ETS79117.1 - 7.4e-11 41.8 0.2 1.6e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS79117.1 - 0.023 13.8 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNA_pol_Rpb4 PF03874.11 ETS79118.1 - 1.7e-20 73.1 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MscS_porin PF12795.2 ETS79118.1 - 0.038 13.3 0.7 0.055 12.7 0.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Ras PF00071.17 ETS79119.1 - 1.9e-17 63.1 0.0 4.3e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETS79119.1 - 1.9e-07 31.6 0.0 2.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS79119.1 - 0.026 13.7 0.1 4 6.6 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.15 ETS79119.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PseudoU_synth_1 PF01416.15 ETS79120.1 - 9.8e-30 103.0 0.0 4e-22 78.6 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 ETS79121.1 - 7.5e-26 89.5 0.0 1.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component MatC_N PF07158.6 ETS79121.1 - 0.043 13.6 1.2 0.083 12.7 0.3 1.8 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus gpUL132 PF11359.3 ETS79123.1 - 0.053 12.8 1.4 0.064 12.5 1.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 CD99L2 PF12301.3 ETS79123.1 - 0.53 9.9 4.1 1.6 8.4 2.8 1.8 1 1 0 1 1 1 0 CD99 antigen like protein 2 YbgS PF13985.1 ETS79124.1 - 0.39 10.6 2.1 0.47 10.3 1.5 1.2 1 0 0 1 1 1 0 YbgS-like protein ATP_bind_3 PF01171.15 ETS79125.1 - 5.4e-40 136.8 0.0 2.9e-28 98.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Peptidase_MA_2 PF13485.1 ETS79125.1 - 2.8e-06 27.4 0.4 1.1e-05 25.4 0.3 2.1 1 0 0 1 1 1 1 Peptidase MA superfamily Asn_synthase PF00733.16 ETS79125.1 - 0.00054 19.5 0.0 0.0021 17.5 0.0 1.9 2 0 0 2 2 2 1 Asparagine synthase NAD_synthase PF02540.12 ETS79125.1 - 0.051 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase SnoaL_2 PF12680.2 ETS79126.1 - 7.4e-07 29.5 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS79126.1 - 0.0032 17.6 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 ETS79126.1 - 0.084 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Tannase PF07519.6 ETS79127.1 - 1.6e-85 287.5 0.5 2e-85 287.2 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS79127.1 - 9e-07 29.0 0.0 3.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS79127.1 - 0.0094 15.5 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS79127.1 - 0.011 14.9 0.1 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS79127.1 - 0.027 14.2 0.1 0.51 10.0 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.20 ETS79128.1 - 7e-26 91.1 5.3 8.9e-26 90.7 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79128.1 - 2.7e-23 83.0 0.5 3.5e-23 82.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79128.1 - 5.3e-10 39.2 3.2 7.4e-10 38.7 2.2 1.1 1 0 0 1 1 1 1 KR domain DUF1379 PF07126.7 ETS79128.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) AdoHcyase_NAD PF00670.16 ETS79128.1 - 0.067 13.0 0.7 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hyd_65N_2 PF14498.1 ETS79129.1 - 4.4e-51 173.8 0.3 6.2e-51 173.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Mito_carr PF00153.22 ETS79130.1 - 4e-47 157.8 8.8 2.9e-17 62.1 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 ETS79131.1 - 5.3e-95 318.5 0.0 1.3e-90 304.2 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 ETS79131.1 - 4.5e-29 99.2 22.6 6.3e-07 29.0 0.1 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat Baculo_PEP_C PF04513.7 ETS79132.1 - 0.2 11.5 4.8 0.4 10.5 3.3 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PuR_N PF09182.5 ETS79132.1 - 3.8 7.1 6.7 0.41 10.2 1.5 1.8 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Tape_meas_lam_C PF09718.5 ETS79132.1 - 9.5 6.2 17.2 1.1 9.2 4.3 2.9 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TPR_11 PF13414.1 ETS79133.1 - 1.5e-05 24.5 4.7 0.0074 15.9 0.1 3.6 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 ETS79133.1 - 2.1e-05 24.0 7.8 0.052 13.4 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS79133.1 - 0.0008 18.9 4.6 0.57 9.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS79133.1 - 0.0027 17.5 2.9 0.5 10.3 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS79133.1 - 0.0055 17.0 3.6 1.9 8.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS79133.1 - 0.018 14.8 1.6 1.9 8.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS79133.1 - 0.029 15.0 5.2 4.4 8.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS79133.1 - 0.31 11.0 5.8 4.7 7.2 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS79133.1 - 0.91 10.1 7.8 0.98 10.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS79133.1 - 2.3 8.9 7.4 2.7 8.7 0.5 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 ETS79135.1 - 1.9e-91 306.6 2.4 4.7e-91 305.3 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 ETS79135.1 - 7.5e-40 136.2 0.0 1.2e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Brix PF04427.13 ETS79137.1 - 1.7e-38 132.2 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain RAMPs PF03787.10 ETS79137.1 - 0.00089 19.1 0.2 0.001 18.9 0.1 1.1 1 0 0 1 1 1 1 RAMP superfamily Ras PF00071.17 ETS79138.1 - 4.4e-63 211.4 0.2 5.1e-63 211.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS79138.1 - 2e-21 76.7 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS79138.1 - 4.8e-13 48.7 0.1 6.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS79138.1 - 3.1e-08 33.5 0.1 4.8e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS79138.1 - 8.1e-05 22.7 0.1 0.00023 21.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 ETS79138.1 - 8.4e-05 22.0 0.1 0.00029 20.3 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS79138.1 - 0.00013 21.1 0.1 0.00022 20.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 ETS79138.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 ETS79138.1 - 0.0021 17.1 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 ETS79138.1 - 0.0026 16.9 0.1 0.0066 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 ETS79138.1 - 0.009 15.9 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 ETS79138.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 ETS79138.1 - 0.017 14.7 0.1 0.051 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS79138.1 - 0.018 15.3 0.1 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 ETS79138.1 - 0.019 14.9 0.3 0.042 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 ETS79138.1 - 0.073 12.3 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 ETS79138.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 ETS79138.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 ETS79139.1 - 7.3e-08 31.9 0.2 1.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4050 PF13259.1 ETS79141.1 - 4.9e-32 110.4 0.0 1e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF2457 PF10446.4 ETS79141.1 - 0.061 12.0 13.4 0.069 11.8 8.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4452 PF14618.1 ETS79143.1 - 2.1e-76 255.3 15.0 2.6e-76 255.0 10.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.18 ETS79144.1 - 3.4e-12 46.0 0.5 6.8e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 ETS79144.1 - 0.033 13.9 1.3 0.073 12.8 0.1 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Mito_carr PF00153.22 ETS79145.1 - 8.8e-65 214.4 5.3 7.4e-24 83.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 ETS79145.1 - 8.7e-23 80.2 2.6 1.9e-12 47.1 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 ETS79145.1 - 3.6e-20 69.6 5.1 2.5e-06 26.3 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 ETS79145.1 - 1.1e-18 65.6 5.7 2.7e-06 26.4 0.6 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 ETS79145.1 - 6.6e-18 62.9 7.1 9.4e-05 21.9 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETS79145.1 - 6.8e-14 51.2 2.6 1.1e-05 24.9 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 ETS79145.1 - 4.5e-09 36.3 0.3 0.00021 21.3 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 ETS79145.1 - 1.4 8.6 4.7 13 5.5 0.0 3.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Peptidase_C48 PF02902.14 ETS79146.1 - 9.1e-19 67.9 0.3 2.2e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain KRAB PF01352.22 ETS79146.1 - 1.3 8.5 5.4 0.21 11.0 0.1 2.4 3 0 0 3 3 3 0 KRAB box FAD_binding_3 PF01494.14 ETS79147.1 - 1.7e-73 247.7 0.0 2.1e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS79147.1 - 6.4e-41 139.7 0.0 1e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 ETS79147.1 - 0.00056 20.2 0.0 0.0019 18.5 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS79147.1 - 0.0048 16.7 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS79147.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 ETS79147.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 ETS79147.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.7 ETS79147.1 - 0.031 13.1 0.0 0.071 12.0 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 ETS79147.1 - 0.048 12.1 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 ETS79147.1 - 0.081 12.2 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 ETS79147.1 - 0.084 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family DAO PF01266.19 ETS79147.1 - 0.095 11.5 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GDI PF00996.13 ETS79147.1 - 0.19 10.0 0.0 0.46 8.7 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor Rick_17kDa_Anti PF05433.10 ETS79150.1 - 0.00084 18.9 11.6 0.00084 18.9 8.0 3.0 2 1 0 2 2 2 1 Glycine zipper 2TM domain Mus7 PF09462.5 ETS79151.1 - 3.5e-122 409.3 0.5 5.8e-122 408.6 0.3 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family adh_short PF00106.20 ETS79152.1 - 7.5e-07 29.2 1.1 0.00018 21.4 0.8 3.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS79152.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 ETS79152.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 ETS79152.1 - 0.036 13.1 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 ETS79152.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS79152.1 - 0.11 12.5 0.3 0.5 10.4 0.1 1.9 1 1 2 3 3 3 0 Shikimate / quinate 5-dehydrogenase Auts2 PF15336.1 ETS79152.1 - 0.19 11.7 0.7 0.26 11.3 0.5 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein GET2 PF08690.5 ETS79153.1 - 8.4e-13 48.2 4.7 1.2e-09 37.8 0.1 3.6 2 2 1 3 3 3 2 GET complex subunit GET2 DUF485 PF04341.7 ETS79154.1 - 0.0048 16.5 0.4 0.18 11.5 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF485 TPR_21 PF09976.4 ETS79154.1 - 0.16 11.8 0.2 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HLH PF00010.21 ETS79155.1 - 1.4e-11 43.9 0.8 2.6e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Peptidase_S64 PF08192.6 ETS79155.1 - 0.03 12.6 0.9 0.04 12.2 0.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 FinO_N PF12602.3 ETS79155.1 - 1.2 9.5 9.6 0.12 12.7 1.9 2.5 2 0 0 2 2 2 0 Fertility inhibition protein N terminal CDC45 PF02724.9 ETS79155.1 - 5.9 4.7 12.7 8.1 4.3 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein OPT PF03169.10 ETS79156.1 - 1e-148 496.5 24.6 1.2e-148 496.3 17.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pentapeptide_2 PF01469.13 ETS79157.1 - 0.0055 16.3 9.8 0.79 9.4 6.2 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) DNA_pol_B_thumb PF14791.1 ETS79157.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb NAD_binding_10 PF13460.1 ETS79158.1 - 3e-19 69.7 0.0 4.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS79158.1 - 3e-06 26.6 0.0 2e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS79158.1 - 0.038 13.4 0.0 0.55 9.6 0.0 2.2 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_hydro_32C PF08244.7 ETS79159.1 - 1.1e-16 60.9 0.8 1.9e-16 60.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 ETS79159.1 - 2.4e-14 53.4 0.0 4.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Nitroreductase PF00881.19 ETS79161.1 - 1.4e-26 93.3 0.0 1.8e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 ETS79161.1 - 0.082 12.0 0.0 4.5 6.4 0.0 2.8 2 1 1 3 3 3 0 Putative TM nitroreductase Ribonuc_L-PSP PF01042.16 ETS79162.1 - 1.1e-13 51.0 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Amnionless PF14828.1 ETS79163.1 - 0.012 14.1 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless Trp_oprn_chp PF09534.5 ETS79163.1 - 0.017 14.7 1.7 0.032 13.8 1.2 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Yip1 PF04893.12 ETS79163.1 - 0.04 13.4 0.3 0.068 12.6 0.2 1.3 1 0 0 1 1 1 0 Yip1 domain SKG6 PF08693.5 ETS79163.1 - 0.88 8.9 2.6 3.2 7.1 1.8 2.0 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Macoilin PF09726.4 ETS79163.1 - 1.5 7.0 4.2 1.7 6.8 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein TMEM154 PF15102.1 ETS79163.1 - 7.1 6.3 6.7 0.95 9.1 0.2 2.2 2 0 0 2 2 2 0 TMEM154 protein family Mucin PF01456.12 ETS79163.1 - 8.2 6.2 25.9 3.4 7.4 8.4 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ank_2 PF12796.2 ETS79164.1 - 1.1e-73 243.5 3.0 4.4e-18 65.4 0.0 11.1 5 1 7 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79164.1 - 8.2e-55 180.0 19.2 3.5e-08 32.8 0.0 16.8 17 1 0 17 17 17 8 Ankyrin repeat Ank_3 PF13606.1 ETS79164.1 - 5.2e-42 137.6 12.5 3.5e-07 29.8 0.0 15.5 16 0 0 16 16 16 7 Ankyrin repeat Ank_4 PF13637.1 ETS79164.1 - 5.8e-40 134.9 10.6 8.7e-08 32.4 0.0 12.1 11 2 1 12 12 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79164.1 - 6.7e-40 134.2 16.4 4.4e-05 23.5 0.1 14.9 11 3 4 15 15 15 8 Ankyrin repeats (many copies) NACHT PF05729.7 ETS79164.1 - 4.7e-09 36.1 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS79164.1 - 4.2e-05 23.6 0.1 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS79164.1 - 0.0045 16.5 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 ETS79164.1 - 0.0049 16.9 0.0 0.02 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS79164.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 ETS79164.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS79164.1 - 0.088 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Ank_2 PF12796.2 ETS79165.1 - 2e-46 156.2 5.7 2.1e-15 56.8 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79165.1 - 3.7e-35 118.0 20.2 7.5e-08 31.8 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 ETS79165.1 - 2.7e-27 92.0 8.4 1.4e-05 24.8 0.0 11.6 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 ETS79165.1 - 1.3e-23 82.8 3.7 9.5e-07 29.1 0.0 6.3 3 3 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79165.1 - 1.1e-20 73.1 4.5 0.00017 21.7 0.0 7.9 6 2 2 8 8 8 4 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.3 ETS79165.1 - 0.0095 16.0 0.2 0.027 14.5 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETS79165.1 - 0.15 12.4 7.1 1.3 9.4 0.5 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Transferase PF02458.10 ETS79167.1 - 4.1e-16 58.4 0.0 5.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family Rav1p_C PF12234.3 ETS79169.1 - 9.5e-266 882.9 0.0 1.2e-265 882.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal PNPOx_C PF10590.4 ETS79169.1 - 0.042 13.3 0.1 0.91 9.0 0.0 2.6 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Sfi1 PF08457.5 ETS79170.1 - 6.7e-21 74.3 92.3 3e-12 45.7 30.9 4.4 3 1 1 4 4 4 4 Sfi1 spindle body protein CHCH PF06747.8 ETS79171.1 - 0.003 17.4 4.0 0.022 14.6 2.5 2.0 1 1 1 2 2 2 2 CHCH domain NDUF_B7 PF05676.8 ETS79171.1 - 0.12 11.8 0.6 3.4 7.1 0.0 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 ETS79171.1 - 0.15 11.8 1.2 0.31 10.8 0.9 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like tRNA-synt_1 PF00133.17 ETS79172.1 - 1.9e-219 729.6 0.1 3.9e-219 728.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS79172.1 - 1.6e-24 86.3 0.0 4.7e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS79172.1 - 4.8e-20 71.5 0.3 6e-09 35.0 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 ETS79172.1 - 0.017 14.2 0.0 0.12 11.4 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.6 ETS79173.1 - 6.8e-124 413.2 0.4 7.7e-124 413.0 0.3 1.0 1 0 0 1 1 1 1 Mo25-like adh_short PF00106.20 ETS79174.1 - 2.7e-22 79.4 1.4 3.4e-22 79.1 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79174.1 - 4.3e-10 39.7 0.0 5.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79174.1 - 2.3e-06 27.4 0.6 3.5e-06 26.7 0.4 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 ETS79174.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS79174.1 - 0.033 13.8 0.1 0.2 11.2 0.0 2.3 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1183 PF06682.7 ETS79174.1 - 0.036 13.6 1.3 0.048 13.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) NAD_binding_10 PF13460.1 ETS79174.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding SWIB PF02201.13 ETS79175.1 - 9.9e-12 44.3 0.0 2.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 ETS79176.1 - 9.1e-70 234.7 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79176.1 - 5e-34 117.5 0.0 1.8e-33 115.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS79176.1 - 1.4e-06 27.5 0.4 0.00021 20.3 0.0 3.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS79176.1 - 8e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS79176.1 - 0.0042 16.8 0.0 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family APC_CDC26 PF10471.4 ETS79177.1 - 4.6e-05 24.0 0.9 0.00021 21.9 0.6 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 XPG_I PF00867.13 ETS79180.1 - 1.9e-25 88.7 0.0 3.9e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 ETS79180.1 - 2.6e-09 37.2 0.0 5.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 ETS79181.1 - 3.3e-19 68.5 0.0 8.3e-18 63.9 0.0 2.6 1 1 0 1 1 1 1 Actin Gly_transf_sug PF04488.10 ETS79182.1 - 3.9e-12 46.4 0.0 8.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 ETS79182.1 - 0.0048 16.1 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 ETS79182.1 - 0.023 13.2 0.1 0.039 12.4 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain tRNA-synt_2b PF00587.20 ETS79183.1 - 1.9e-23 82.9 0.0 3.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 ETS79183.1 - 3.4e-11 43.0 10.5 1e-10 41.5 7.3 1.7 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 ETS79183.1 - 1.8 8.1 6.5 0.92 9.0 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Lebercilin PF15619.1 ETS79183.1 - 2.1 7.7 17.4 6.9 6.0 12.0 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.1 ETS79183.1 - 2.7 8.4 7.6 17 5.9 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3395 PF11875.3 ETS79185.1 - 0.32 10.6 11.6 0.014 15.0 0.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DUF2968 PF11180.3 ETS79185.1 - 3.7 6.9 27.0 1.9 7.8 8.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) GMC_oxred_N PF00732.14 ETS79186.1 - 1e-29 103.6 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS79186.1 - 2.6e-17 63.4 0.0 5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS79186.1 - 1.6e-06 27.2 1.6 0.0013 17.7 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS79186.1 - 4.4e-06 25.8 3.4 0.00077 18.4 1.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 ETS79186.1 - 4.4e-05 23.6 0.6 0.13 12.3 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS79186.1 - 0.00036 20.4 0.3 0.0015 18.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS79186.1 - 0.0091 14.5 0.2 0.014 13.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 ETS79186.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS79186.1 - 0.01 15.6 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS79186.1 - 0.016 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 ETS79186.1 - 0.043 12.6 0.1 0.07 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Mito_fiss_Elm1 PF06258.6 ETS79186.1 - 0.1 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Pyr_redox PF00070.22 ETS79186.1 - 0.13 12.6 0.9 2.8 8.4 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.22 ETS79187.1 - 3.9e-29 100.1 0.4 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_4 PF08386.5 ETS79188.1 - 3.3e-22 78.3 0.0 6.7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS79188.1 - 8.8e-17 61.4 0.0 1.8e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS79188.1 - 1.7e-10 41.1 2.6 3.8e-09 36.7 1.8 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS79188.1 - 0.00024 20.9 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family MS_channel PF00924.13 ETS79189.1 - 9.1e-20 70.8 1.7 1.7e-19 69.9 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 ETS79189.1 - 0.00078 18.5 0.2 0.0027 16.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 ETS79189.1 - 0.0027 16.9 0.1 0.0072 15.6 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 ETS79189.1 - 0.0065 16.5 0.1 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS79189.1 - 0.015 15.1 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain DUF1129 PF06570.6 ETS79189.1 - 0.063 12.5 2.8 0.65 9.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) VIT1 PF01988.14 ETS79189.1 - 0.34 10.3 3.8 0.14 11.5 0.3 2.0 2 0 0 2 2 2 0 VIT family Sugar_tr PF00083.19 ETS79190.1 - 2.9e-90 303.0 20.2 3.5e-90 302.7 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79190.1 - 6.4e-16 57.9 39.6 6.4e-13 48.1 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIIIAC PF06686.6 ETS79190.1 - 0.015 15.0 0.8 0.096 12.4 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Abp2 PF09441.5 ETS79191.1 - 1e-81 273.0 0.0 1.5e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.22 ETS79192.1 - 7.3e-51 169.8 4.9 1.3e-17 63.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 ETS79192.1 - 0.0014 18.3 0.1 0.0037 17.0 0.1 1.7 1 0 0 1 1 1 1 UcrQ family DUF2590 PF10761.4 ETS79192.1 - 0.0063 16.2 0.0 0.018 14.7 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2590) Mak10 PF04112.8 ETS79193.1 - 4.7e-47 159.3 0.0 7.4e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 ETS79194.1 - 1.7e-23 81.8 1.8 1.7e-23 81.8 1.2 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.5 ETS79194.1 - 0.13 12.2 0.5 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Peptidase_M16_C PF05193.16 ETS79195.1 - 3.6e-15 56.1 0.0 7.4e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS79195.1 - 2e-11 43.8 0.2 9.8e-11 41.6 0.1 2.0 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) RNA_pol_Rpc82 PF05645.8 ETS79196.1 - 1.2e-41 142.9 0.0 1.1e-40 139.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 ETS79196.1 - 1.5e-14 53.5 1.0 2.7e-14 52.7 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 ETS79196.1 - 0.00022 20.7 0.3 0.016 14.7 0.0 2.7 2 1 0 2 2 2 1 TFIIE alpha subunit Methyltransf_31 PF13847.1 ETS79197.1 - 8.4e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79197.1 - 6.7e-11 42.5 0.0 2.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79197.1 - 1.2e-10 41.9 0.1 8.2e-10 39.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.8 ETS79197.1 - 1e-09 37.9 0.2 3.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 ETS79197.1 - 3e-08 33.6 0.5 6e-08 32.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS79197.1 - 7.9e-08 32.1 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS79197.1 - 1.3e-05 24.3 0.0 3.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 ETS79197.1 - 2.3e-05 23.5 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 ETS79197.1 - 2.6e-05 23.6 0.1 4.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS79197.1 - 0.00016 21.9 0.0 0.00044 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79197.1 - 0.00031 21.1 0.0 0.00086 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS79197.1 - 0.0009 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 ETS79197.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 ETS79197.1 - 0.0016 17.5 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 ETS79197.1 - 0.0028 17.2 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 ETS79197.1 - 0.0055 17.5 0.1 0.035 14.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 ETS79197.1 - 0.0066 16.0 0.2 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 ETS79197.1 - 0.013 14.1 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.11 ETS79197.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Uso1_p115_head PF04869.9 ETS79198.1 - 3.4e-95 318.4 0.0 8.4e-95 317.1 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region XRN_N PF03159.13 ETS79199.1 - 2.5e-106 354.3 0.0 2.5e-106 354.3 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 ETS79199.1 - 0.0011 18.7 2.4 0.0023 17.7 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Med7 PF05983.6 ETS79199.1 - 0.21 11.3 1.2 0.57 9.9 0.8 1.7 1 0 0 1 1 1 0 MED7 protein RasGAP PF00616.14 ETS79200.1 - 3.7e-45 154.0 0.1 7.8e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 ETS79200.1 - 1e-08 35.2 0.0 3.2e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Trp_repressor PF01371.14 ETS79201.1 - 0.0093 15.8 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Trp repressor protein NAD_binding_10 PF13460.1 ETS79201.1 - 0.0094 15.9 0.3 0.0098 15.9 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS79201.1 - 0.047 12.9 0.6 0.057 12.6 0.4 1.3 1 1 0 1 1 1 0 NmrA-like family Sial-lect-inser PF09264.5 ETS79201.1 - 0.051 12.9 0.2 0.06 12.6 0.1 1.0 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion DUF3433 PF11915.3 ETS79203.1 - 1.7e-19 69.7 15.8 1.6e-13 50.5 0.7 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) JmjC PF02373.17 ETS79205.1 - 6.1e-10 39.3 0.3 2.7e-09 37.2 0.2 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 ETS79205.1 - 1.1e-05 25.4 10.1 1.1e-05 25.4 7.0 2.7 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 ETS79205.1 - 0.033 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 ETS79206.1 - 2.9e-34 118.4 23.6 4e-34 117.9 16.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 ETS79207.1 - 6.5e-41 138.5 0.3 7.4e-41 138.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Inhibitor_I9 PF05922.11 ETS79209.1 - 0.0039 17.7 0.1 0.0068 16.9 0.1 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 ParA PF10609.4 ETS79209.1 - 0.14 12.0 0.3 0.64 9.9 0.0 1.9 1 1 0 2 2 2 0 ParA/MinD ATPase like CCDC92 PF14916.1 ETS79210.1 - 0.0067 15.9 1.8 0.0067 15.9 1.3 6.3 5 2 2 7 7 7 1 Coiled-coil domain of unknown function CH PF00307.26 ETS79210.1 - 0.086 12.8 3.0 0.093 12.7 0.1 2.7 3 0 0 3 3 3 0 Calponin homology (CH) domain Reo_sigmaC PF04582.7 ETS79210.1 - 0.83 8.7 11.8 0.78 8.8 0.3 3.1 3 1 0 3 3 3 0 Reovirus sigma C capsid protein MitMem_reg PF13012.1 ETS79211.1 - 1.2e-38 131.7 0.2 3.2e-38 130.3 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 ETS79211.1 - 1.2e-28 99.1 0.0 2.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 ETS79212.1 - 3.7e-58 195.7 0.0 5e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 ETS79212.1 - 5.6e-15 54.7 0.0 1.4e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 ETS79212.1 - 2.1e-05 24.4 0.0 3.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS79212.1 - 0.00011 22.9 0.1 0.00024 21.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS79212.1 - 0.012 14.6 0.1 0.02 13.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 ETS79212.1 - 0.027 14.7 0.1 0.08 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Coprogen_oxidas PF01218.13 ETS79214.1 - 2.6e-134 446.4 0.4 3.6e-134 445.9 0.0 1.3 2 0 0 2 2 2 1 Coproporphyrinogen III oxidase DUF4407 PF14362.1 ETS79215.1 - 3.4 6.5 7.5 2.2 7.1 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SMP PF04927.7 ETS79215.1 - 4 7.4 11.2 9.7 6.2 7.8 1.8 1 1 0 1 1 1 0 Seed maturation protein Fungal_trans PF04082.13 ETS79216.1 - 3.4e-09 35.9 0.9 6.5e-09 35.0 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 ETS79218.1 - 0.00031 20.3 0.3 0.00085 18.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS79218.1 - 0.069 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 ETS79219.1 - 2.2e-15 56.2 27.6 2.2e-15 56.2 19.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 ETS79219.1 - 0.0074 15.5 4.1 0.023 13.9 2.8 1.9 1 1 0 1 1 1 1 Nodulin-like 7tm_7 PF08395.7 ETS79219.1 - 0.14 11.1 1.5 3 6.7 0.1 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor COesterase PF00135.23 ETS79220.1 - 2.6e-95 320.1 0.0 3.5e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS79220.1 - 0.00013 21.6 0.4 0.0011 18.6 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_75 PF07335.6 ETS79221.1 - 2.6e-21 76.1 0.2 2.6e-21 76.1 0.2 1.9 2 1 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 Ala_racemase_N PF01168.15 ETS79222.1 - 1.7e-37 129.1 0.0 2e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-HIT PF04438.11 ETS79223.1 - 7.4e-10 38.2 9.1 1.1e-09 37.7 6.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_S7e PF01251.13 ETS79223.1 - 0.038 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S7e LSM14 PF12701.2 ETS79224.1 - 3.2e-34 116.6 0.0 5.6e-34 115.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 ETS79224.1 - 5.7e-17 62.1 0.3 1.6e-16 60.7 0.2 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 ETS79224.1 - 6.1e-06 26.0 0.2 2.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF3138 PF11336.3 ETS79224.1 - 3 5.9 8.8 4.7 5.2 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Clr5 PF14420.1 ETS79226.1 - 3.1e-06 26.9 0.3 7e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Clr5 domain DUF2745 PF10922.3 ETS79226.1 - 0.22 11.4 1.9 0.48 10.3 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) zf-C2H2_4 PF13894.1 ETS79226.1 - 2.7 8.5 16.3 0.79 10.2 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Abhydrolase_6 PF12697.2 ETS79227.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family RRM_6 PF14259.1 ETS79227.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tcf25 PF04910.9 ETS79228.1 - 2.1e-70 237.5 0.0 6e-70 235.9 0.0 1.8 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Nop53 PF07767.6 ETS79228.1 - 7.8 5.3 30.4 0.11 11.5 11.4 2.7 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) HMA PF00403.21 ETS79229.1 - 4.5e-15 55.5 0.8 7.2e-15 54.8 0.6 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Phosphoesterase PF04185.9 ETS79230.1 - 3.1e-20 72.7 0.5 1.1e-19 70.9 0.3 1.7 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.13 ETS79231.1 - 5e-14 51.7 0.1 7.9e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79231.1 - 3.1e-07 30.1 7.9 6.9e-07 29.0 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.7 ETS79231.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 cwf21 domain Thiolase_C PF02803.13 ETS79232.1 - 3.4e-12 45.8 0.2 1.1e-11 44.1 0.2 1.9 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 ETS79232.1 - 2.9e-05 23.6 0.1 0.002 17.7 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 ETS79232.1 - 8.6e-05 21.6 0.3 0.00043 19.3 0.1 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain SpoVAD PF07451.6 ETS79232.1 - 0.0021 16.5 0.6 0.029 12.8 0.1 2.6 3 0 0 3 3 3 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 ETS79232.1 - 0.0099 15.3 0.4 0.033 13.6 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS79232.1 - 0.026 14.3 1.7 0.4 10.5 0.0 2.7 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF2231 PF09990.4 ETS79233.1 - 0.044 14.1 2.0 0.044 14.1 1.4 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Oxidored_q5_N PF01059.12 ETS79233.1 - 0.31 10.9 5.5 0.24 11.3 0.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Sugar_tr PF00083.19 ETS79235.1 - 5.8e-81 272.3 21.4 6.6e-81 272.1 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79235.1 - 1.9e-10 40.0 39.8 1.5e-09 37.0 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS79236.1 - 7.1e-20 70.9 0.1 1.2e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79236.1 - 6.4e-08 32.3 12.4 1.5e-07 31.1 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thr_synth_N PF14821.1 ETS79238.1 - 7.5e-28 96.3 0.0 1.6e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 ETS79238.1 - 1.6e-18 67.0 0.0 1.5e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MIP PF00230.15 ETS79239.1 - 8.4e-50 169.3 13.3 1.1e-49 168.9 9.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Methyltransf_11 PF08241.7 ETS79241.1 - 6.6e-10 39.3 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS79241.1 - 4.8e-08 32.8 0.0 1.3e-07 31.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79241.1 - 7.8e-08 32.7 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79241.1 - 5e-05 22.9 0.0 0.00012 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS79241.1 - 0.0069 16.7 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS79241.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.15 ETS79242.1 - 2.2e-119 399.1 4.3 2.7e-119 398.9 3.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 ETS79242.1 - 6.7e-47 158.1 0.0 1.9e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 ETS79242.1 - 4.5e-20 72.0 0.0 9.9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain IncA PF04156.9 ETS79243.1 - 0.1 12.1 0.2 0.85 9.1 0.1 2.1 2 0 0 2 2 2 0 IncA protein MGC-24 PF05283.6 ETS79243.1 - 3.8 7.2 12.4 4.7 6.9 6.9 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) P16-Arc PF04699.9 ETS79245.1 - 1.3e-57 194.1 0.0 1.5e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) CN_hydrolase PF00795.17 ETS79246.1 - 1.3e-21 76.8 0.0 7.4e-21 74.3 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.18 ETS79247.1 - 1.2e-16 60.4 0.4 2.2e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS79247.1 - 1.5e-05 24.8 0.1 5.4e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like RabGAP-TBC PF00566.13 ETS79248.1 - 5.1e-48 163.3 0.0 9.7e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Fungal_trans PF04082.13 ETS79251.1 - 2.8e-25 88.6 0.0 5.2e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79251.1 - 6.1e-08 32.4 13.7 1.2e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIG1 PF04548.11 ETS79251.1 - 0.0069 15.5 2.2 1.2 8.1 0.0 2.7 3 0 0 3 3 3 2 AIG1 family Spc24 PF08286.6 ETS79251.1 - 0.16 11.6 0.3 0.43 10.2 0.1 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 A_deaminase PF00962.17 ETS79252.1 - 6.3e-67 225.8 0.0 7.1e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.4 ETS79252.1 - 0.015 15.2 0.2 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Sel1 PF08238.7 ETS79252.1 - 0.33 11.6 3.1 0.62 10.7 1.2 2.2 2 0 0 2 2 2 0 Sel1 repeat Pyridoxal_deC PF00282.14 ETS79253.1 - 9.1e-78 261.2 0.0 1.2e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETS79253.1 - 1.7e-06 27.0 0.0 6.3e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Nbl1_Borealin_N PF10444.4 ETS79253.1 - 0.013 14.8 0.3 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Abhydrolase_3 PF07859.8 ETS79254.1 - 4.5e-35 121.1 0.0 2.7e-24 85.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS79254.1 - 0.03 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Lipase_3 PF01764.20 ETS79254.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.16 ETS79255.1 - 1.4e-96 323.2 0.0 2.2e-96 322.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 ETS79255.1 - 2.3e-05 23.5 0.0 6.2e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cutinase PF01083.17 ETS79256.1 - 1.3e-51 174.8 4.2 1.5e-51 174.6 2.9 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 ETS79256.1 - 1.9e-05 25.0 0.0 2.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 ETS79256.1 - 7.2e-05 22.4 0.2 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79256.1 - 0.00064 19.5 0.6 0.00079 19.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS79256.1 - 0.00096 18.7 0.1 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 ETS79256.1 - 0.003 17.4 0.1 0.0034 17.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 ETS79256.1 - 0.0038 16.6 0.2 0.0051 16.2 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 ETS79256.1 - 0.0042 16.9 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.8 ETS79256.1 - 0.0084 15.6 0.7 0.01 15.4 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 ETS79256.1 - 0.0084 15.4 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) LIP PF03583.9 ETS79256.1 - 0.069 12.3 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase GMC_oxred_C PF05199.8 ETS79257.1 - 4.5e-34 117.8 0.0 7.9e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS79257.1 - 2.4e-28 99.1 0.0 3.2e-25 88.8 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS79257.1 - 2.9e-06 26.4 0.0 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS79257.1 - 1.6e-05 23.9 0.0 0.00085 18.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS79257.1 - 6.6e-05 22.8 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS79257.1 - 0.00045 20.1 0.1 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 ETS79257.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS79257.1 - 0.014 15.4 0.0 0.87 9.6 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS79257.1 - 0.014 13.8 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS79257.1 - 0.016 14.1 0.2 0.023 13.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETS79257.1 - 0.079 11.8 0.1 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS79257.1 - 0.086 11.9 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS79257.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SDA1 PF05285.7 ETS79258.1 - 9.3e-87 291.3 53.8 2.5e-86 289.8 31.7 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 ETS79258.1 - 2.7e-20 72.4 0.1 6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.5 ETS79258.1 - 0.19 11.9 6.8 0.081 13.1 0.3 3.1 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil Beta-TrCP_D PF12125.3 ETS79260.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 D domain of beta-TrCP Dioxygenase_C PF00775.16 ETS79261.1 - 2.7e-12 46.3 0.0 4.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Alpha-amylase PF00128.19 ETS79263.1 - 5.9e-29 101.4 1.6 2.6e-28 99.3 1.1 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 ETS79263.1 - 8.8e-08 30.4 0.1 0.067 10.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Kin17_mid PF10357.4 ETS79263.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein bZIP_1 PF00170.16 ETS79265.1 - 2.9e-10 39.9 11.0 8.9e-10 38.3 7.7 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS79265.1 - 0.00028 20.6 11.2 0.00028 20.6 7.7 2.8 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 ETS79265.1 - 2.8 7.5 20.6 0.18 11.3 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF972 PF06156.8 ETS79265.1 - 6.8 7.0 8.7 1.5 9.1 0.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3533 PF12051.3 ETS79266.1 - 2.2e-114 382.1 17.7 2.5e-114 381.9 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2615 PF11027.3 ETS79266.1 - 2.9 7.8 4.0 8.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Glyco_hydro_2_C PF02836.12 ETS79267.1 - 1.2e-05 24.4 0.0 2.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETS79267.1 - 0.00011 22.6 0.0 0.0013 19.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 ETS79267.1 - 0.0034 16.9 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain MFS_1 PF07690.11 ETS79268.1 - 8.9e-33 113.4 40.1 2.2e-28 99.0 17.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 ETS79268.1 - 0.00071 17.7 1.8 0.0013 16.8 1.2 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.6 ETS79269.1 - 2.3e-19 69.9 6.8 5.2e-17 62.3 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box PF00646.28 ETS79270.1 - 0.0025 17.4 0.1 0.0073 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS79270.1 - 0.0089 15.7 0.3 0.0089 15.7 0.2 1.9 2 0 0 2 2 2 1 F-box-like FAD_binding_3 PF01494.14 ETS79271.1 - 1.5e-22 80.1 0.1 2e-21 76.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS79271.1 - 0.00041 19.3 0.9 0.26 10.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS79271.1 - 0.00049 19.1 0.1 0.62 8.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS79271.1 - 0.0011 18.1 0.4 0.057 12.4 0.2 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS79271.1 - 0.0032 17.4 1.6 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 ETS79271.1 - 0.022 14.3 0.1 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 ETS79271.1 - 0.073 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS79271.1 - 0.079 13.3 2.3 0.28 11.6 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS79271.1 - 0.11 11.1 1.3 1.1 7.8 0.2 2.2 1 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 ETS79271.1 - 0.12 12.1 0.8 0.95 9.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Cutinase PF01083.17 ETS79272.1 - 6.1e-46 156.3 1.7 7e-46 156.1 1.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 ETS79272.1 - 7.3e-05 22.6 0.0 9.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 ETS79272.1 - 0.0014 18.1 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 ETS79272.1 - 0.0079 15.5 0.0 0.0099 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 ETS79272.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HpcH_HpaI PF03328.9 ETS79273.1 - 1.9e-26 92.3 0.9 2.5e-26 91.9 0.6 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.11 ETS79274.1 - 3.9e-31 108.0 26.0 3.9e-31 108.0 18.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS79274.1 - 0.024 14.4 0.9 0.024 14.4 0.6 2.5 3 0 0 3 3 3 0 MFS_1 like family PD40 PF07676.7 ETS79275.1 - 4e-35 118.9 23.1 1.4e-05 24.6 0.1 9.4 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETS79275.1 - 4.2e-12 45.3 0.3 0.028 12.9 0.0 6.3 5 1 0 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.1 ETS79275.1 - 9.3e-07 27.6 0.7 1.6 7.1 0.0 5.7 4 2 0 5 5 5 2 Oligogalacturonate lyase Methyltransf_23 PF13489.1 ETS79276.1 - 7e-13 48.6 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79276.1 - 3e-11 43.6 0.0 5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79276.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79276.1 - 1.2e-07 31.3 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79276.1 - 4.2e-05 24.1 0.0 7.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS79276.1 - 0.012 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 ETS79276.1 - 0.017 15.4 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETS79276.1 - 0.032 14.2 0.0 0.22 11.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETS79276.1 - 0.053 12.6 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SKG6 PF08693.5 ETS79277.1 - 0.0011 18.1 0.1 0.0026 17.0 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 ETS79277.1 - 0.013 14.6 1.0 0.027 13.7 0.2 1.7 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Granulin PF00396.13 ETS79277.1 - 0.38 10.8 5.1 0.41 10.7 0.7 2.5 2 0 0 2 2 2 0 Granulin Mid2 PF04478.7 ETS79277.1 - 1.3 8.4 6.9 0.24 10.8 0.2 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Ank_2 PF12796.2 ETS79279.1 - 6.6e-10 39.2 0.0 0.00017 21.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS79279.1 - 7.1e-10 38.8 0.1 2.1e-06 27.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS79279.1 - 2.6e-08 34.1 0.0 0.012 16.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79279.1 - 3.4e-08 32.9 0.0 0.017 15.3 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.25 ETS79279.1 - 6.5e-08 32.0 0.1 3.7e-05 23.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Rapamycin_bind PF08771.6 ETS79279.1 - 0.081 13.0 1.3 0.38 10.8 0.9 2.2 1 0 0 1 1 1 0 Rapamycin binding domain Prominin PF05478.6 ETS79279.1 - 0.71 7.3 6.1 1.1 6.7 4.3 1.1 1 0 0 1 1 1 0 Prominin adh_short_C2 PF13561.1 ETS79280.1 - 1.9e-28 99.8 0.0 2.1e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS79280.1 - 9.3e-20 71.1 1.1 1.3e-19 70.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79280.1 - 2.2e-06 27.4 0.5 3.5e-06 26.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_3 PF00933.16 ETS79281.1 - 6.8e-85 284.6 0.0 1e-84 284.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS79281.1 - 1.2e-70 237.5 0.0 2.4e-70 236.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS79281.1 - 2e-17 62.8 0.8 4.2e-17 61.8 0.6 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS79281.1 - 1e-16 60.9 0.2 1.7e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 PA14 domain MFS_1 PF07690.11 ETS79282.1 - 2e-48 164.9 34.3 2e-48 164.9 23.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79282.1 - 2.8e-12 45.9 7.1 2.8e-12 45.9 4.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS79282.1 - 5.7e-06 24.8 1.4 5.7e-06 24.8 0.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 ETS79282.1 - 0.058 11.4 18.3 0.0098 13.9 1.2 3.3 4 1 1 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M20 PF01546.23 ETS79283.1 - 1.2e-10 41.1 0.9 1.7e-10 40.6 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS79283.1 - 3.2e-06 26.8 1.9 7.9e-06 25.5 0.4 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain MFS_1 PF07690.11 ETS79284.1 - 5.9e-38 130.4 31.8 5.9e-38 130.4 22.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79284.1 - 0.00019 20.1 24.0 0.0004 19.0 16.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 ETS79284.1 - 0.011 15.7 0.1 0.011 15.7 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) DUF2985 PF11204.3 ETS79284.1 - 0.085 12.6 8.2 0.27 11.0 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) Cu-oxidase_2 PF07731.9 ETS79286.1 - 5.2e-47 158.8 9.1 4.5e-43 146.0 0.8 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS79286.1 - 2.6e-42 143.2 6.9 2.1e-38 130.6 1.5 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS79286.1 - 2.9e-38 131.2 3.9 4e-36 124.3 0.4 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 ETS79286.1 - 0.011 15.5 0.0 2.2 8.1 0.0 3.3 3 1 1 4 4 4 0 Cupredoxin-like domain FTR1 PF03239.9 ETS79287.1 - 3.6e-85 285.6 9.1 4.4e-85 285.3 6.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family B12D PF06522.6 ETS79287.1 - 0.51 10.0 1.9 21 4.8 0.0 2.6 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ferric_reduct PF01794.14 ETS79288.1 - 5.2e-17 62.0 9.5 5.2e-17 62.0 6.6 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS79288.1 - 1.5e-15 57.4 0.0 3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS79288.1 - 1.2e-14 54.0 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 ETS79288.1 - 0.0012 19.3 0.0 0.052 14.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 ETS79288.1 - 0.25 10.7 12.9 0.049 12.9 2.9 2.9 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB PepSY_TM_2 PF13703.1 ETS79288.1 - 9.9 6.4 10.7 2.9 8.1 0.8 4.1 3 2 0 3 3 3 0 PepSY-associated TM helix MBOAT_2 PF13813.1 ETS79289.1 - 0.0026 17.8 1.3 0.0057 16.7 0.7 1.6 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.17 ETS79291.1 - 1.4e-45 155.7 0.0 1.7e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VARLMGL PF14383.1 ETS79291.1 - 0.57 9.3 2.3 0.62 9.2 0.4 1.9 2 0 0 2 2 2 0 DUF761-associated sequence motif Methyltransf_2 PF00891.13 ETS79292.1 - 1.8e-28 99.3 0.0 2.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase DUF977 PF06163.6 ETS79292.1 - 0.0023 17.6 0.0 0.099 12.3 0.0 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF977) p450 PF00067.17 ETS79293.1 - 1.5e-23 83.0 0.0 4.3e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS79294.1 - 5.1e-07 28.5 0.0 5.9e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec1 PF00995.18 ETS79294.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Sec1 family p450 PF00067.17 ETS79295.1 - 1.3e-25 89.8 0.0 1.5e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 ETS79296.1 - 2.5e-07 30.6 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS79296.1 - 5.2e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 ETS79296.1 - 0.0012 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_7 PF13176.1 ETS79296.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.2 ETS79297.1 - 0.029 14.0 1.0 0.11 12.1 0.7 2.2 1 0 0 1 1 1 0 F-box-like p450 PF00067.17 ETS79298.1 - 2.9e-63 214.0 0.0 3.6e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3759 PF12585.3 ETS79300.1 - 1.9e-39 133.4 9.2 2.2e-39 133.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Dioxygenase_C PF00775.16 ETS79301.1 - 6.2e-07 28.8 0.1 1.2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase DNA_pol_A PF00476.15 ETS79301.1 - 0.11 11.0 0.8 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase family A Glyco_hydro_3 PF00933.16 ETS79302.1 - 1.8e-80 270.1 0.0 1.3e-79 267.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS79302.1 - 1.2e-65 221.2 0.0 3.5e-65 219.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS79302.1 - 9.4e-18 63.9 0.2 1.8e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS79302.1 - 3.5e-12 46.1 0.0 6.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.19 ETS79303.1 - 6.6e-86 288.6 26.3 7.8e-86 288.4 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79303.1 - 2.6e-22 79.0 32.1 4.3e-22 78.3 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2754 PF10953.3 ETS79303.1 - 0.18 11.8 2.9 0.83 9.7 2.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Sugar_tr PF00083.19 ETS79304.1 - 4e-104 348.6 19.0 4.6e-104 348.5 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79304.1 - 6e-29 100.8 46.9 9.5e-24 83.7 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS79304.1 - 0.00017 20.1 17.0 0.0012 17.2 0.2 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein phage_tail_N PF08400.5 ETS79304.1 - 0.12 12.1 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Fungal_trans_2 PF11951.3 ETS79305.1 - 4.4e-15 55.1 4.4 7.8e-15 54.3 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79305.1 - 2.8e-07 30.3 12.6 5.7e-07 29.3 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 ETS79306.1 - 3.1e-27 95.8 0.1 4.5e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS79306.1 - 1.8e-20 73.5 1.7 2.4e-20 73.1 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79306.1 - 4.9e-10 39.3 0.6 7.2e-10 38.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS79306.1 - 0.034 13.5 0.1 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETS79306.1 - 0.08 12.5 1.1 0.39 10.3 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transketolase_N PF00456.16 ETS79307.1 - 6.5e-126 419.6 0.0 1.3e-125 418.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS79307.1 - 1.7e-39 135.1 0.0 3.8e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 ETS79307.1 - 2.2e-09 36.6 0.0 6e-08 31.9 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 ETS79307.1 - 8.4e-08 32.1 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 ETS79307.1 - 1.6e-05 23.8 0.1 2.3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MFS_1 PF07690.11 ETS79308.1 - 8.7e-30 103.6 37.2 8.7e-30 103.6 25.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_Coat_B PF05356.6 ETS79308.1 - 0.043 13.4 4.0 0.27 10.9 0.1 3.3 3 0 0 3 3 3 0 Phage Coat protein B p450 PF00067.17 ETS79309.1 - 1.9e-88 297.0 0.0 2.2e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS79310.1 - 6.2e-32 110.6 59.6 7.9e-29 100.4 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.19 ETS79311.1 - 1.7e-34 119.3 0.5 2.7e-34 118.6 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase RasGEF PF00617.14 ETS79312.1 - 9.7e-48 162.3 0.1 1.7e-47 161.6 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS79312.1 - 1.4e-13 50.8 0.1 3e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Nop PF01798.13 ETS79313.1 - 6.1e-55 184.6 1.4 1.7e-54 183.2 1.0 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 ETS79313.1 - 5e-26 90.2 0.1 9.5e-26 89.3 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 ETS79313.1 - 2e-17 63.0 0.2 6.8e-17 61.3 0.1 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 ETS79314.1 - 5e-116 387.5 0.0 5.6e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 ETS79315.1 - 6.5e-14 51.4 0.1 1.4e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 RRP7 PF12923.2 ETS79315.1 - 0.038 14.0 1.9 0.1 12.6 1.3 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) RbsD_FucU PF05025.8 ETS79315.1 - 0.083 13.2 0.5 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family Ribosomal_S2 PF00318.15 ETS79316.1 - 1.6e-40 138.5 0.0 7.8e-21 74.2 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 MVL PF12151.3 ETS79316.1 - 0.017 14.7 3.6 0.017 14.7 2.5 2.0 2 0 0 2 2 2 0 Mannan-binding protein AA_permease_2 PF13520.1 ETS79317.1 - 2.9e-30 105.1 19.8 3.5e-30 104.8 13.7 1.0 1 0 0 1 1 1 1 Amino acid permease ubiquitin PF00240.18 ETS79319.1 - 2.3e-05 23.7 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 ETS79319.1 - 0.065 13.8 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Pro_isomerase PF00160.16 ETS79321.1 - 2e-45 154.7 0.0 2.2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 ETS79322.1 - 2.7e-15 56.6 0.0 4.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 ETS79323.1 - 8e-23 79.6 0.1 1.4e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 ETS79323.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain DUF4557 PF15101.1 ETS79324.1 - 0.2 11.4 14.5 0.4 10.4 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DHHW PF14286.1 ETS79324.1 - 4.3 6.5 7.8 8.5 5.5 5.4 1.4 1 0 0 1 1 1 0 DHHW protein Rtf2 PF04641.7 ETS79324.1 - 5.6 6.0 11.3 0.16 11.1 3.2 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4407 PF14362.1 ETS79324.1 - 6.4 5.6 13.4 16 4.3 9.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Esterase_phd PF10503.4 ETS79325.1 - 6e-10 38.7 0.9 6.4e-09 35.3 0.1 2.4 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 ETS79325.1 - 4e-06 26.6 0.1 8.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS79325.1 - 7.4e-05 22.0 0.4 0.00016 20.9 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 ETS79325.1 - 0.012 14.1 0.1 0.068 11.6 0.1 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 ETS79325.1 - 0.068 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DNA_binding_1 PF01035.15 ETS79326.1 - 4.3e-25 87.2 0.0 6.6e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain NdhL PF10716.4 ETS79327.1 - 0.037 13.7 3.7 0.67 9.7 0.3 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit GMC_oxred_N PF00732.14 ETS79328.1 - 7.5e-52 176.3 0.0 9.7e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS79328.1 - 1.3e-28 100.0 0.0 2.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS79328.1 - 7.4e-05 21.8 0.0 0.11 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS79328.1 - 0.00038 19.4 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS79328.1 - 0.0015 18.5 1.1 0.0068 16.3 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS79328.1 - 0.0017 18.2 0.0 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS79328.1 - 0.023 13.5 0.1 0.43 9.3 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 ETS79328.1 - 0.091 11.6 0.0 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS79328.1 - 0.13 12.2 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1772 PF08592.6 ETS79329.1 - 2.8e-12 46.5 6.0 1.2e-11 44.5 4.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Acyltransferase PF01553.16 ETS79329.1 - 0.039 13.3 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase APH PF01636.18 ETS79329.1 - 0.061 13.0 1.4 0.078 12.6 1.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4231 PF14015.1 ETS79329.1 - 0.47 10.4 4.4 4.3 7.3 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) ERCC4 PF02732.10 ETS79330.1 - 7.9e-19 67.8 0.0 2.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Phage_Gp23 PF10669.4 ETS79330.1 - 0.00047 20.2 5.5 0.0011 19.0 3.8 1.6 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) HET PF06985.6 ETS79331.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Kinesin PF00225.18 ETS79332.1 - 4.5e-90 301.7 0.0 4.5e-90 301.7 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain DUF3037 PF11236.3 ETS79332.1 - 0.17 11.9 4.4 2.9 7.9 0.4 4.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) GvpG PF05120.7 ETS79333.1 - 0.12 12.2 0.5 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 Gas vesicle protein G Activator_LAG-3 PF11498.3 ETS79333.1 - 0.19 10.4 9.9 0.26 9.9 6.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 ETS79333.1 - 0.33 10.1 3.4 0.62 9.2 2.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NACHT PF05729.7 ETS79334.1 - 0.0029 17.2 0.0 0.019 14.6 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS79334.1 - 0.018 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RasGEF_N_2 PF14663.1 ETS79334.1 - 0.018 14.9 0.1 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Thi4 PF01946.12 ETS79335.1 - 6.1e-102 339.5 0.1 7.3e-102 339.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 ETS79335.1 - 1.4e-09 37.3 0.3 1.6e-08 33.8 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS79335.1 - 9e-06 24.8 0.2 1.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS79335.1 - 1.5e-05 24.8 0.2 4.1e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS79335.1 - 3.9e-05 23.4 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS79335.1 - 0.00016 20.6 2.2 0.0031 16.4 0.3 2.7 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS79335.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS79335.1 - 0.00038 20.5 0.1 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS79335.1 - 0.004 17.2 0.0 0.45 10.6 0.0 2.4 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 ETS79335.1 - 0.045 12.2 0.3 0.066 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 ETS79335.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ETS79335.1 - 0.14 10.7 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DNA_binding_1 PF01035.15 ETS79336.1 - 7e-22 76.9 0.3 9e-22 76.6 0.2 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.17 ETS79337.1 - 1.1e-22 80.8 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 ETS79337.1 - 0.038 13.3 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.7 ETS79339.1 - 0.18 11.5 2.8 0.4 10.4 1.9 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-DHHC PF01529.15 ETS79339.1 - 0.27 10.5 11.4 0.59 9.5 7.9 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Methyltransf_18 PF12847.2 ETS79341.1 - 1.9e-05 25.2 0.0 3.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79341.1 - 3.9e-05 23.2 0.0 0.0001 21.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79341.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79341.1 - 0.007 16.8 0.1 0.017 15.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS79341.1 - 0.023 15.0 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 ETS79341.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 ETS79341.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 ETS79341.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BTB_2 PF02214.17 ETS79342.1 - 9.3e-05 22.5 0.1 0.0098 16.0 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain TSC22 PF01166.13 ETS79343.1 - 0.1 12.5 0.3 0.1 12.5 0.2 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Laminin_II PF06009.7 ETS79343.1 - 2.1 8.1 15.2 12 5.6 6.4 2.7 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 ETS79343.1 - 3.3 7.4 29.3 0.075 12.7 12.4 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spatacsin_C PF14649.1 ETS79343.1 - 3.5 6.4 13.9 0.22 10.3 4.4 2.1 1 1 1 2 2 2 0 Spatacsin C-terminus DENN PF02141.16 ETS79344.1 - 5.6e-39 133.7 0.0 9.9e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 ETS79344.1 - 9.3e-06 25.5 0.0 3.1e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 ETS79344.1 - 0.0017 18.7 2.8 0.0017 18.7 2.0 2.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 ETS79344.1 - 1.2 8.7 14.9 0.26 10.8 4.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) ASFV_J13L PF05568.6 ETS79347.1 - 0.06 12.8 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2217 PF10265.4 ETS79347.1 - 0.16 10.7 0.1 0.19 10.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SR-25 PF10500.4 ETS79347.1 - 0.62 9.4 6.2 0.76 9.1 4.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 ETS79347.1 - 3.8 7.5 8.1 5.3 7.1 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Mito_fiss_reg PF05308.6 ETS79347.1 - 4.7 6.5 10.8 6.7 5.9 7.5 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Pirin PF02678.11 ETS79348.1 - 4.7e-31 106.8 0.0 8.7e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 ETS79348.1 - 7.6e-26 90.2 0.0 2.2e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 ETS79348.1 - 2.2e-06 27.0 0.6 0.00019 20.8 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Slx4 PF09494.5 ETS79349.1 - 0.021 14.5 0.2 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Slx4 endonuclease Lipase_GDSL_2 PF13472.1 ETS79351.1 - 3.5e-20 72.8 0.0 4.2e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 ETS79351.1 - 1.5e-05 24.7 0.0 0.22 11.2 0.0 2.8 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS79351.1 - 9.7e-05 22.3 0.0 0.00026 20.8 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3959 PF13105.1 ETS79351.1 - 0.031 13.6 0.3 0.055 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Glyco_hydro_28 PF00295.12 ETS79352.1 - 2.2e-115 385.0 20.1 2.2e-115 385.0 13.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 DUF2217 PF10265.4 ETS79352.1 - 0.28 9.8 5.7 0.38 9.4 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3425 PF11905.3 ETS79353.1 - 9e-26 90.3 0.4 3.8e-25 88.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) PI-PLC-X PF00388.14 ETS79354.1 - 0.051 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain bZIP_1 PF00170.16 ETS79355.1 - 2.5e-10 40.1 5.7 5.2e-10 39.1 4.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS79355.1 - 2.9e-07 30.1 7.9 6.1e-07 29.1 5.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS79355.1 - 0.0081 16.4 3.3 0.015 15.5 2.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Uso1_p115_C PF04871.8 ETS79355.1 - 0.028 14.3 0.9 0.059 13.3 0.1 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4164 PF13747.1 ETS79355.1 - 0.8 9.8 6.7 1.3 9.1 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) WD40_alt PF14077.1 ETS79355.1 - 1 9.0 3.1 17 5.1 0.3 2.3 1 1 1 2 2 2 0 Alternative WD40 repeat motif Clat_adaptor_s PF01217.15 ETS79356.1 - 9.9e-45 151.7 0.0 2e-44 150.7 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1 PF00133.17 ETS79358.1 - 6.3e-39 133.4 0.0 9.9e-28 96.4 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETS79358.1 - 2.3e-19 69.3 0.0 2.9e-11 42.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 ETS79358.1 - 7.4e-12 45.2 1.2 2.5e-11 43.5 0.2 2.2 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 ETS79358.1 - 3.3e-08 33.0 0.0 5.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1590 PF07629.6 ETS79358.1 - 0.018 14.6 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Methyltransf_23 PF13489.1 ETS79359.1 - 5.4e-20 71.7 0.0 7.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79359.1 - 6.1e-10 39.6 0.0 3.5e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79359.1 - 8.2e-10 39.0 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79359.1 - 9.6e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79359.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS79359.1 - 0.00022 21.5 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS79359.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETS79359.1 - 0.021 13.9 0.0 0.052 12.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS79359.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 ETS79359.1 - 0.15 11.4 0.0 0.93 8.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Lipase_3 PF01764.20 ETS79360.1 - 2.5e-09 36.8 0.0 5.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 ETS79360.1 - 0.0098 15.7 0.1 0.024 14.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS79360.1 - 0.013 15.1 0.1 0.041 13.4 0.0 1.9 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS79360.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 ETS79361.1 - 3.7e-24 85.4 0.0 7.5e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS79361.1 - 1.6e-06 27.3 3.9 0.0047 15.8 1.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS79361.1 - 1.8e-05 25.0 0.5 0.0012 19.1 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS79361.1 - 6.8e-05 21.5 1.1 0.00036 19.1 0.8 1.9 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS79361.1 - 7.3e-05 22.7 0.3 0.00016 21.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS79361.1 - 0.00033 19.4 0.2 0.59 8.6 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS79361.1 - 0.00056 18.8 2.6 0.00063 18.6 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS79361.1 - 0.0018 18.1 0.5 0.0044 16.9 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS79361.1 - 0.0055 15.8 1.3 0.67 8.9 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS79361.1 - 0.04 13.0 0.1 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 ETS79361.1 - 0.047 12.6 2.7 4.5 6.0 0.5 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein ApbA PF02558.11 ETS79361.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 ETS79361.1 - 0.13 12.5 0.1 4.9 7.4 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS79361.1 - 0.48 9.7 2.5 0.65 9.3 0.9 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F-box-like PF12937.2 ETS79362.1 - 0.089 12.5 0.0 0.37 10.5 0.0 2.1 1 1 0 1 1 1 0 F-box-like Pyridoxal_deC PF00282.14 ETS79363.1 - 7.6e-17 60.8 0.0 9.6e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.14 ETS79364.1 - 2.8e-27 95.1 0.1 3.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 ETS79364.1 - 0.0032 16.2 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETS79364.1 - 0.12 11.4 0.1 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.11 ETS79365.1 - 6e-20 71.2 57.5 1e-17 63.9 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 ETS79366.1 - 1.8e-20 73.5 10.2 3e-18 66.3 0.1 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Alpha_kinase PF02816.13 ETS79366.1 - 2.8e-07 30.4 0.0 8.3e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Alpha-kinase family IncA PF04156.9 ETS79366.1 - 9 5.8 7.8 17 4.8 5.4 1.4 1 0 0 1 1 1 0 IncA protein EthD PF07110.6 ETS79367.1 - 0.005 17.7 0.2 0.005 17.7 0.1 2.1 3 0 0 3 3 3 1 EthD domain adh_short PF00106.20 ETS79368.1 - 1.3e-26 93.5 0.2 1.7e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79368.1 - 1.4e-10 41.1 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS79368.1 - 2.1e-06 27.7 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 ETS79368.1 - 7.4e-05 21.7 0.1 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS79368.1 - 0.0033 16.8 0.2 0.0088 15.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS79368.1 - 0.014 15.1 1.4 0.04 13.7 1.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 ETS79368.1 - 0.061 13.4 0.5 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 ETS79368.1 - 0.064 13.8 0.3 0.17 12.4 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETS79368.1 - 0.086 12.8 0.3 2.1 8.4 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain NmrA PF05368.8 ETS79369.1 - 8.7e-37 126.6 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 ETS79369.1 - 6.6e-10 38.1 0.0 8.5e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS79369.1 - 5.1e-09 36.4 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS79369.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS79369.1 - 0.0021 16.9 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 ETS79370.1 - 5.7e-20 71.2 0.0 9.5e-20 70.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trypsin PF00089.21 ETS79371.1 - 1e-05 25.2 11.7 7.1e-05 22.4 7.9 2.3 2 1 0 2 2 2 1 Trypsin Pro_Al_protease PF02983.9 ETS79371.1 - 0.0051 16.7 0.4 0.0051 16.7 0.3 2.5 2 0 0 2 2 2 1 Alpha-lytic protease prodomain ADP_ribosyl_GH PF03747.9 ETS79372.1 - 2.1e-41 142.6 2.8 3.3e-41 141.9 1.9 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sugar_tr PF00083.19 ETS79373.1 - 1.8e-80 270.7 21.4 2.1e-80 270.5 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79373.1 - 5.1e-27 94.5 25.7 5.1e-27 94.5 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_racemase PF05544.6 ETS79374.1 - 9.3e-61 205.4 0.0 1.3e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Proline racemase GAF_2 PF13185.1 ETS79375.1 - 3.6e-07 30.7 0.0 4.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 GAF domain MFS_1 PF07690.11 ETS79376.1 - 1.1e-39 136.1 31.1 1.1e-39 136.1 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS79376.1 - 0.017 15.1 4.4 0.41 10.7 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) YajC PF02699.10 ETS79376.1 - 0.33 10.6 1.2 2.7 7.7 0.0 2.7 3 0 0 3 3 3 0 Preprotein translocase subunit Amidohydro_1 PF01979.15 ETS79377.1 - 2e-39 136.1 0.0 2.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS79377.1 - 3.3e-19 69.9 0.0 1.5e-17 64.5 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS79377.1 - 4.9e-14 52.3 0.0 5.3e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS79377.1 - 3.2e-13 49.2 0.1 1.2e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 Amidohydrolase Fungal_trans PF04082.13 ETS79378.1 - 8.9e-23 80.4 4.0 1.7e-22 79.5 2.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_18 PF12847.2 ETS79379.1 - 1.5e-09 38.4 0.1 2.6e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79379.1 - 6.5e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS79379.1 - 6.7e-06 25.9 0.0 9.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79379.1 - 6.9e-06 26.4 0.1 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS79379.1 - 2.5e-05 24.2 0.1 4.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79379.1 - 4.4e-05 23.1 0.0 6.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 ETS79379.1 - 5.6e-05 23.1 0.1 8.5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MTS PF05175.9 ETS79379.1 - 0.0041 16.5 0.1 0.0086 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS79379.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.5 ETS79379.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Pox_MCEL PF03291.11 ETS79379.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Sec23_trunk PF04811.10 ETS79379.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain AAA PF00004.24 ETS79380.1 - 9.6e-52 174.6 0.0 1.5e-38 132.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 ETS79380.1 - 1.8e-09 37.0 0.2 5.5e-09 35.5 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 ETS79380.1 - 4.6e-08 33.2 0.0 0.001 19.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS79380.1 - 8.5e-08 32.3 0.0 0.0068 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain CDC48_N PF02359.13 ETS79380.1 - 1e-07 31.7 0.0 2.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_14 PF13173.1 ETS79380.1 - 4.4e-07 29.8 0.0 0.031 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS79380.1 - 7.3e-07 30.0 0.0 0.0099 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 ETS79380.1 - 8e-07 29.1 0.2 4.4e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 ETS79380.1 - 1e-06 28.6 0.7 0.18 11.4 0.0 3.6 2 1 1 3 3 3 2 Archaeal ATPase AAA_5 PF07728.9 ETS79380.1 - 1.1e-06 28.4 0.0 0.001 18.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETS79380.1 - 2.8e-06 26.8 0.3 0.46 9.8 0.0 3.9 2 2 1 4 4 4 2 AAA domain TIP49 PF06068.8 ETS79380.1 - 3.2e-06 26.1 0.0 0.044 12.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus KaiC PF06745.8 ETS79380.1 - 7.3e-06 25.2 0.1 0.00077 18.6 0.1 2.3 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 ETS79380.1 - 8.9e-06 25.3 0.2 0.018 14.7 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_24 PF13479.1 ETS79380.1 - 1.2e-05 25.0 0.5 0.062 12.8 0.2 2.8 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 ETS79380.1 - 1.2e-05 25.4 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase PhoH PF02562.11 ETS79380.1 - 1.4e-05 24.4 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Mg_chelatase PF01078.16 ETS79380.1 - 1.9e-05 23.9 0.1 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 ETS79380.1 - 4.7e-05 22.9 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 ETS79380.1 - 0.00012 21.2 0.0 0.063 12.3 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 ETS79380.1 - 0.00015 21.4 0.1 2.7 7.6 0.0 3.6 4 0 0 4 4 3 1 NACHT domain IstB_IS21 PF01695.12 ETS79380.1 - 0.00025 20.4 0.2 0.12 11.8 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 ETS79380.1 - 0.00029 21.1 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS79380.1 - 0.00039 20.7 0.3 0.19 12.0 0.1 3.0 2 1 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 ETS79380.1 - 0.0004 20.2 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS79380.1 - 0.003 16.6 0.0 0.82 8.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 ETS79380.1 - 0.005 16.3 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 ETS79380.1 - 0.0072 15.2 0.1 1.1 8.1 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain ATP-synt_ab PF00006.20 ETS79380.1 - 0.032 13.7 0.1 3.6 7.0 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 ETS79380.1 - 0.047 13.2 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS79380.1 - 0.047 13.6 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 ETS79380.1 - 0.052 12.4 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 ETS79380.1 - 0.059 13.4 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 ETS79380.1 - 0.086 11.7 0.0 0.56 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 ETS79380.1 - 0.094 11.6 0.0 0.98 8.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_3 PF07726.6 ETS79380.1 - 0.13 11.8 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 ETS79380.1 - 0.14 11.0 0.0 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 ETS79380.1 - 0.16 12.2 0.1 11 6.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain IPT PF01745.11 ETS79380.1 - 0.17 11.0 0.0 3 6.9 0.0 2.5 2 1 0 2 2 2 0 Isopentenyl transferase PPV_E1_C PF00519.12 ETS79380.1 - 0.37 9.3 0.0 2.4 6.6 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase CTP_transf_1 PF01148.15 ETS79381.1 - 2.1e-16 60.3 7.1 4.1e-15 56.1 1.1 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Pil1 PF13805.1 ETS79381.1 - 0.18 10.9 1.1 0.24 10.5 0.4 1.4 1 1 0 1 1 1 0 Eisosome component PIL1 DUF4010 PF13194.1 ETS79381.1 - 0.55 9.4 6.1 0.068 12.4 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) KxDL PF10241.4 ETS79382.1 - 8.3e-30 102.5 1.6 1.2e-29 102.0 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 ETS79382.1 - 6e-05 22.1 2.0 0.059 12.2 0.0 2.1 2 0 0 2 2 2 2 C-terminal domain of homeodomain 1 ATP-sulfurylase PF01747.12 ETS79383.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 ATP-sulfurylase Ten_N PF06484.7 ETS79383.1 - 0.03 13.4 2.3 0.036 13.1 1.6 1.2 1 0 0 1 1 1 0 Teneurin Intracellular Region Cir_N PF10197.4 ETS79385.1 - 0.0021 18.0 1.6 0.0021 18.0 1.1 4.4 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR F-box-like PF12937.2 ETS79386.1 - 2.7e-05 23.8 1.9 6.4e-05 22.5 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS79386.1 - 0.011 15.4 1.1 0.011 15.4 0.8 2.2 3 0 0 3 3 3 0 F-box domain IU_nuc_hydro PF01156.14 ETS79387.1 - 3.2e-21 75.8 0.0 3.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_zinc_N PF00107.21 ETS79388.1 - 1.3e-27 95.8 0.5 2.1e-27 95.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS79388.1 - 6.7e-18 65.8 0.1 1.5e-17 64.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS79388.1 - 9.7e-11 41.4 0.0 2.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 ETS79388.1 - 0.071 12.6 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MULE PF10551.4 ETS79389.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 MULE transposase domain DEAD PF00270.24 ETS79390.1 - 7e-34 116.7 0.0 2.1e-33 115.1 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 ETS79390.1 - 4.8e-21 74.0 0.0 9.5e-21 73.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETS79390.1 - 7.1e-18 64.2 0.0 1.7e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS79390.1 - 0.0026 17.6 0.3 0.011 15.5 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS79390.1 - 0.0049 16.5 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS79390.1 - 0.015 15.4 0.1 0.2 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain Band_7 PF01145.20 ETS79391.1 - 2e-28 99.5 2.6 3.3e-28 98.8 1.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 ETS79391.1 - 0.055 12.9 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF4547 PF15080.1 ETS79391.1 - 0.22 10.9 1.6 3.4 7.0 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4547) Glyco_hydro_3 PF00933.16 ETS79392.1 - 5.5e-56 189.7 0.2 8.3e-56 189.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS79392.1 - 1.1e-43 149.3 0.1 2.6e-43 148.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS79392.1 - 3.6e-27 94.0 0.3 7.7e-27 93.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.19 ETS79393.1 - 1.3e-94 317.3 21.5 1.5e-94 317.1 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79393.1 - 2.7e-30 105.2 48.9 1.9e-24 86.0 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS79393.1 - 0.00021 21.2 9.7 0.06 13.3 1.4 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1228) MFS_2 PF13347.1 ETS79393.1 - 0.0039 15.6 2.7 0.0039 15.6 1.9 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 ETS79393.1 - 0.0046 15.1 10.2 0.15 10.1 0.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector HK PF02110.10 ETS79393.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Ank_2 PF12796.2 ETS79394.1 - 4e-13 49.5 0.7 4.8e-10 39.6 0.2 3.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS79394.1 - 3.8e-11 43.1 3.1 0.0074 16.7 0.0 6.4 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79394.1 - 1.4e-10 41.0 1.6 2.4e-08 33.9 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS79394.1 - 1.6e-09 37.0 0.1 2.9e-05 23.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 ETS79394.1 - 1.7e-06 27.7 3.5 0.0035 17.4 0.0 4.8 7 0 0 7 7 7 2 Ankyrin repeat Dioxygenase_C PF00775.16 ETS79395.1 - 5.7e-09 35.4 0.3 8.6e-09 34.8 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase GMC_oxred_N PF00732.14 ETS79396.1 - 4.3e-63 213.2 0.0 6.3e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS79396.1 - 5.2e-39 133.8 0.0 1.1e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS79396.1 - 4.6e-06 25.7 0.1 0.0015 17.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS79396.1 - 2.1e-05 23.6 0.0 0.0046 15.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS79396.1 - 0.0093 15.9 0.1 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS79396.1 - 0.019 13.8 0.1 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS79396.1 - 0.069 13.0 0.1 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 ETS79398.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS79398.1 - 1.4e-06 28.4 0.5 2.5e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS79398.1 - 8.7e-06 25.6 0.4 0.00053 19.8 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS79398.1 - 9.3e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 ETS79398.1 - 0.00032 20.8 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS79398.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ENTH PF01417.15 ETS79399.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 ENTH domain TauD PF02668.11 ETS79400.1 - 1.6e-09 37.8 0.0 4.2e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS79400.1 - 0.022 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 CsiD Frataxin_Cyay PF01491.11 ETS79401.1 - 3.3e-33 113.7 0.1 4.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Clr5 PF14420.1 ETS79402.1 - 0.017 14.9 1.0 0.038 13.8 0.7 1.6 1 0 0 1 1 1 0 Clr5 domain DUF382 PF04037.8 ETS79403.1 - 3.6e-60 201.4 0.3 8.1e-60 200.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 ETS79403.1 - 3.1e-20 71.2 5.8 7.2e-20 70.1 4.1 1.7 1 0 0 1 1 1 1 PSP FAM176 PF14851.1 ETS79403.1 - 8.8 5.9 12.6 1.3 8.6 1.1 2.6 2 0 0 2 2 2 0 FAM176 family TPT PF03151.11 ETS79404.1 - 1.6e-38 131.7 3.4 1.6e-38 131.7 2.3 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETS79404.1 - 2e-08 33.5 11.7 5.7e-08 32.0 8.1 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETS79404.1 - 0.001 19.0 29.7 0.0011 18.9 6.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 ETS79404.1 - 0.0033 16.5 1.3 0.16 11.0 0.0 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter M-factor PF03855.8 ETS79404.1 - 0.072 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 M-factor ATP-synt_ab PF00006.20 ETS79405.1 - 6.1e-62 208.9 0.0 9.3e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS79405.1 - 4.5e-25 88.3 1.0 7.8e-25 87.5 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS79405.1 - 6e-23 80.8 0.5 1.7e-22 79.3 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 ETS79405.1 - 0.0015 18.7 0.0 0.1 12.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS79405.1 - 0.0087 15.4 0.4 0.038 13.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 ETS79405.1 - 0.0097 15.6 0.1 1 9.0 0.0 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 ETS79405.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 ETS79405.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 ETS79405.1 - 0.015 14.4 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 ETS79405.1 - 0.028 14.0 0.1 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 ETS79405.1 - 0.044 13.7 0.3 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 ETS79405.1 - 0.051 13.7 0.0 0.19 11.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS79405.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RnfC_N PF13375.1 ETS79405.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.17 ETS79405.1 - 0.09 11.6 0.7 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain F-box-like PF12937.2 ETS79406.1 - 0.0033 17.1 0.4 0.012 15.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like AAA PF00004.24 ETS79407.1 - 4.1e-41 140.2 0.0 2.2e-38 131.4 0.0 3.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS79407.1 - 8e-08 32.4 0.8 0.0013 18.7 0.0 3.9 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 ETS79407.1 - 2.1e-06 26.9 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS79407.1 - 2.9e-05 24.2 0.5 0.0037 17.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 ETS79407.1 - 0.0002 22.1 0.0 0.00076 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS79407.1 - 0.00033 20.5 0.0 0.00099 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 ETS79407.1 - 0.00093 19.0 0.0 0.0093 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS79407.1 - 0.0017 18.6 0.0 0.013 15.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 ETS79407.1 - 0.0033 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 ETS79407.1 - 0.0042 16.8 0.2 0.013 15.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 ETS79407.1 - 0.012 15.3 0.0 0.042 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 ETS79407.1 - 0.016 13.9 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 ETS79407.1 - 0.017 15.3 0.0 0.066 13.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.9 ETS79407.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 ETS79407.1 - 0.02 14.3 1.5 0.58 9.5 0.2 3.1 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.16 ETS79407.1 - 0.042 13.0 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 ETS79407.1 - 0.082 13.2 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 ETS79407.1 - 0.096 12.3 0.1 7.8 6.1 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 ETS79407.1 - 0.11 12.0 0.4 0.22 11.0 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS79407.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS79407.1 - 0.48 9.8 2.4 11 5.3 0.0 2.9 2 2 1 3 3 3 0 AAA-like domain VEFS-Box PF09733.4 ETS79408.1 - 0.05 13.2 0.0 0.05 13.2 0.0 1.7 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Glypican PF01153.14 ETS79409.1 - 3.6 6.0 8.2 1.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Glypican Methyltransf_2 PF00891.13 ETS79410.1 - 2e-29 102.5 0.2 5.6e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 ETS79410.1 - 0.028 14.1 0.0 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain YwqJ-deaminase PF14431.1 ETS79410.1 - 0.067 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 YwqJ-like deaminase DUF1289 PF06945.8 ETS79411.1 - 0.16 11.4 0.3 0.16 11.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DAO PF01266.19 ETS79412.1 - 2e-37 128.9 1.4 2.6e-37 128.5 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS79412.1 - 0.0063 16.3 1.8 2.4 7.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS79412.1 - 0.051 13.6 0.6 0.17 11.9 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CN_hydrolase PF00795.17 ETS79413.1 - 2.9e-21 75.6 0.0 4.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HATPase_c_3 PF13589.1 ETS79415.1 - 3.1e-17 62.5 0.0 1.3e-15 57.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 ETS79415.1 - 1.2e-05 24.9 0.0 0.00017 21.2 0.0 2.5 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 ETS79415.1 - 9.7e-05 22.0 0.0 0.00082 19.0 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amastin PF07344.6 ETS79416.1 - 7.4 6.1 10.7 0.84 9.2 0.6 2.6 2 1 1 3 3 3 0 Amastin surface glycoprotein Beta-lactamase PF00144.19 ETS79418.1 - 5.1e-47 160.5 0.6 6.4e-47 160.1 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETS79418.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HSF_DNA-bind PF00447.12 ETS79419.1 - 1.7e-28 98.7 0.4 3.9e-28 97.6 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding ERM PF00769.14 ETS79419.1 - 2.9 7.3 12.1 0.52 9.7 0.8 2.9 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Pro_isomerase PF00160.16 ETS79420.1 - 2e-41 141.7 0.0 3.6e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DS PF01916.12 ETS79423.1 - 9.6e-145 481.2 0.0 1.1e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 ETS79423.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase B5 PF03484.10 ETS79423.1 - 0.12 12.2 0.3 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase B5 domain Myb_DNA-binding PF00249.26 ETS79424.1 - 4.3e-07 29.8 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAB3GAP2_N PF14655.1 ETS79424.1 - 8.8 5.2 5.8 17 4.2 4.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glycos_transf_1 PF00534.15 ETS79425.1 - 1.1e-31 109.5 0.0 1.6e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 ETS79425.1 - 6.7e-10 39.3 0.1 3.5e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 ETS79425.1 - 3.9e-07 30.3 0.1 1e-05 25.7 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 ETS79425.1 - 1.1e-06 28.4 0.1 2.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 ETS79425.1 - 0.00042 20.5 0.0 0.00084 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ank_2 PF12796.2 ETS79426.1 - 2.5e-27 95.0 0.1 1.7e-11 44.2 0.0 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79426.1 - 3.7e-20 70.6 5.5 0.0003 20.4 0.0 8.3 8 1 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 ETS79426.1 - 7.6e-20 69.0 5.2 0.058 13.6 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 ETS79426.1 - 1.7e-18 66.6 8.2 1.4e-05 25.4 0.0 7.2 5 3 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79426.1 - 1.3e-15 57.0 10.8 0.0015 18.7 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) IPK PF03770.11 ETS79427.1 - 7.4e-55 185.6 0.0 1.3e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.2 ETS79429.1 - 1.2e-30 104.5 37.5 1.8e-08 33.8 1.2 8.4 8 2 1 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS79429.1 - 1.8e-21 75.6 38.6 4.4e-07 29.5 0.7 6.8 4 3 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 ETS79429.1 - 3.1e-07 29.4 36.3 0.55 10.4 0.1 11.6 10 4 3 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 ETS79429.1 - 8.7e-06 25.4 11.0 0.016 14.7 0.3 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 ETS79429.1 - 8.6e-05 22.2 30.6 0.71 10.1 0.1 9.6 10 2 1 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 ETS79429.1 - 0.0018 18.1 41.5 2.8 8.5 0.0 12.1 13 0 0 13 13 13 3 Leucine rich repeat zf-Di19 PF05605.7 ETS79430.1 - 0.00057 19.9 8.7 0.042 13.9 0.5 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 ETS79430.1 - 0.0034 17.5 16.2 0.61 10.5 0.5 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger DUF629 PF04780.7 ETS79430.1 - 0.032 12.7 3.2 0.056 11.9 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 ETS79430.1 - 0.047 13.7 5.9 0.091 12.8 0.5 3.3 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 ETS79430.1 - 0.056 13.0 4.2 1.4 8.5 0.1 3.4 3 0 0 3 3 3 0 GAGA factor Eapp_C PF10238.4 ETS79430.1 - 0.077 12.8 2.8 0.85 9.5 0.0 3.2 3 1 0 3 3 3 0 E2F-associated phosphoprotein Ank_2 PF12796.2 ETS79432.1 - 1.1e-36 124.9 5.2 1.8e-16 60.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79432.1 - 5.8e-26 88.9 11.2 4.9e-06 26.0 0.1 7.0 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 ETS79432.1 - 6.7e-26 90.1 0.0 1.1e-08 35.3 0.0 4.5 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79432.1 - 7.1e-22 75.3 1.0 7.7e-05 22.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 ETS79432.1 - 3.3e-20 71.6 4.2 3.9e-06 26.9 1.1 5.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) His_Phos_1 PF00300.17 ETS79433.1 - 3.9e-18 66.0 0.1 5.4e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 ETS79433.1 - 0.13 11.6 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 ETS79434.1 - 1.2e-31 109.8 1.0 3.1e-31 108.5 1.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79434.1 - 5.5e-20 72.1 0.0 8.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79434.1 - 1.1e-10 41.4 0.3 1.1e-10 41.4 0.2 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 ETS79434.1 - 7.6e-07 29.3 0.3 1.1e-06 28.7 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS79434.1 - 7.3e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 ETS79434.1 - 7.6e-05 22.0 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS79434.1 - 0.00015 21.2 0.2 0.0003 20.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1772 PF08592.6 ETS79435.1 - 2.9e-23 82.1 1.3 5e-23 81.3 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DEAD PF00270.24 ETS79436.1 - 1.8e-42 144.6 0.0 3.2e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 ETS79436.1 - 3.2e-23 81.0 0.6 6.4e-23 80.0 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETS79436.1 - 4e-21 74.6 0.0 9.4e-21 73.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2457 PF10446.4 ETS79436.1 - 0.17 10.6 23.7 0.26 9.9 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETS79436.1 - 0.61 7.9 21.1 0.85 7.4 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETS79436.1 - 1.2 8.3 21.3 1.9 7.7 14.7 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 ETS79436.1 - 1.7 7.0 21.2 2.4 6.5 14.7 1.1 1 0 0 1 1 1 0 Daxx Family FYDLN_acid PF09538.5 ETS79436.1 - 2.9 8.4 24.4 5.5 7.6 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 ETS79436.1 - 3.3 7.0 18.8 5.6 6.2 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 ETS79436.1 - 3.4 7.0 10.2 6.3 6.2 7.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.9 ETS79436.1 - 3.7 7.0 17.6 6.4 6.2 12.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 ETS79436.1 - 8.6 6.2 20.3 20 4.9 14.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 6PF2K PF01591.13 ETS79437.1 - 1.8e-78 262.6 0.0 2.4e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETS79437.1 - 3.7e-34 118.1 0.0 6.5e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 ETS79437.1 - 3.7e-10 39.8 0.1 7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS79437.1 - 0.00063 20.5 0.2 0.0089 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 ETS79437.1 - 0.00094 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 ETS79437.1 - 0.089 11.8 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Na_Ca_ex PF01699.19 ETS79438.1 - 1.1e-27 96.2 23.1 9.1e-14 51.2 5.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YfhO PF09586.5 ETS79438.1 - 0.0041 15.2 2.4 0.0067 14.5 1.7 1.3 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF454 PF04304.8 ETS79438.1 - 0.0057 16.6 3.0 0.0057 16.6 2.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF454) HemY_N PF07219.8 ETS79438.1 - 0.035 13.6 0.2 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DUF3328 PF11807.3 ETS79438.1 - 0.47 10.0 2.8 2 8.0 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) DUF829 PF05705.9 ETS79439.1 - 1e-41 143.2 0.3 1.6e-41 142.6 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 ETS79439.1 - 0.036 13.9 1.0 0.041 13.7 0.7 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4410 PF14366.1 ETS79441.1 - 0.57 9.9 5.6 0.16 11.7 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) 2OG-FeII_Oxy_3 PF13640.1 ETS79442.1 - 0.1 13.1 0.2 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2985 PF11204.3 ETS79443.1 - 1.7e-29 101.4 5.8 3.5e-29 100.3 4.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Neur_chan_memb PF02932.11 ETS79443.1 - 0.092 12.6 0.1 0.092 12.6 0.1 2.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 ETS79444.1 - 9.8e-53 178.9 1.3 4.7e-37 127.5 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79444.1 - 1.1e-20 73.8 1.5 4.9e-19 68.4 0.4 3.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS79444.1 - 3.5e-05 22.9 0.0 0.00013 20.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 ETS79444.1 - 0.00024 20.9 0.1 0.00091 19.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Methyltransf_26 PF13659.1 ETS79445.1 - 0.093 12.7 1.1 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF605 PF04652.11 ETS79445.1 - 2.8 7.2 5.6 3.9 6.7 3.9 1.1 1 0 0 1 1 1 0 Vta1 like Clathrin PF00637.15 ETS79446.1 - 2.5e-22 79.0 8.2 1.1e-21 76.9 2.1 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 ETS79446.1 - 1.9e-10 40.3 0.8 4.4e-10 39.2 0.1 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 ETS79446.1 - 5.5e-05 22.9 4.8 0.00012 21.8 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS79446.1 - 0.00033 20.3 3.6 0.00062 19.4 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS79446.1 - 0.00056 19.5 2.6 0.0011 18.6 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS79446.1 - 0.00087 19.3 1.8 0.0018 18.3 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger TPR_11 PF13414.1 ETS79446.1 - 0.0017 17.9 0.3 0.054 13.1 0.0 2.9 2 0 0 2 2 2 1 TPR repeat zf-Apc11 PF12861.2 ETS79446.1 - 0.003 17.3 1.7 0.0077 16.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 ETS79446.1 - 0.0061 16.5 4.4 0.012 15.5 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 ETS79446.1 - 0.0073 16.8 0.1 13 6.7 0.0 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Prok-RING_1 PF14446.1 ETS79446.1 - 0.047 13.4 1.9 0.1 12.3 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TPR_12 PF13424.1 ETS79446.1 - 0.07 13.0 11.5 0.25 11.3 0.2 4.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS79446.1 - 0.097 12.6 2.1 0.19 11.7 0.1 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat zf-Nse PF11789.3 ETS79446.1 - 0.11 12.0 1.4 0.27 10.8 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETS79446.1 - 0.33 10.8 4.6 0.72 9.7 3.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 ETS79446.1 - 0.34 10.9 2.6 0.79 9.7 1.8 1.6 1 0 0 1 1 1 0 RING-like domain TPR_8 PF13181.1 ETS79446.1 - 0.96 9.3 4.6 0.72 9.7 0.5 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS79446.1 - 1.1 9.6 6.6 3.4 8.0 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TauD PF02668.11 ETS79447.1 - 1.7e-21 77.0 0.0 3.5e-21 76.0 0.0 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 ETS79448.1 - 1.6e-13 50.1 1.6 1.6e-13 50.1 1.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 ETS79449.1 - 1.2e-80 270.7 0.0 1.8e-80 270.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS79449.1 - 3.1e-48 164.2 0.0 8.2e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS79449.1 - 1.1e-18 66.9 0.1 5.2e-18 64.7 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 ETS79449.1 - 8.7e-10 38.4 0.5 1.6e-09 37.5 0.3 1.4 1 0 0 1 1 1 1 PA14 domain DUF840 PF05801.6 ETS79449.1 - 0.051 13.7 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) He_PIG PF05345.7 ETS79450.1 - 1.8 8.6 4.9 1.9 8.6 0.6 2.6 2 0 0 2 2 2 0 Putative Ig domain DUF2880 PF11082.3 ETS79451.1 - 0.14 12.1 0.8 0.28 11.0 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2880) SNARE PF05739.14 ETS79452.1 - 9.6e-12 44.4 5.9 2.6e-11 43.0 4.1 1.8 1 0 0 1 1 1 1 SNARE domain Snapin_Pallidin PF14712.1 ETS79452.1 - 0.019 15.2 4.3 0.85 9.9 0.6 2.8 2 1 0 2 2 2 0 Snapin/Pallidin OST-HTH PF12872.2 ETS79452.1 - 0.071 12.9 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Syntaxin PF00804.20 ETS79452.1 - 2.5 8.2 6.3 5 7.3 0.0 2.9 2 1 0 2 2 2 0 Syntaxin Meth_synt_2 PF01717.13 ETS79453.1 - 1.4e-17 63.6 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS79453.1 - 4.4e-09 36.0 0.0 0.005 16.1 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain KH_1 PF00013.24 ETS79454.1 - 4.6e-42 141.4 12.2 2.2e-14 52.8 1.0 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 ETS79454.1 - 8.7e-31 105.0 17.3 6.1e-12 44.9 1.2 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 ETS79454.1 - 2.9e-12 45.9 2.4 0.0071 15.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETS79454.1 - 2.2e-08 33.5 5.3 0.13 11.9 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 ETS79454.1 - 0.00035 20.3 1.1 0.89 9.4 0.0 3.4 3 0 0 3 3 3 1 NusA-like KH domain SLS PF14611.1 ETS79454.1 - 0.0097 15.3 0.0 6.3 6.1 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial inner-membrane-bound regulator DHHA1 PF02272.14 ETS79454.1 - 2.3 7.9 6.7 18 5.1 0.4 2.6 2 0 0 2 2 2 0 DHHA1 domain Baculo_PEP_C PF04513.7 ETS79455.1 - 0.003 17.3 12.4 0.85 9.4 0.1 4.5 3 2 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Mistic PF11458.3 ETS79455.1 - 0.018 15.4 0.1 0.18 12.1 0.0 2.5 1 1 1 2 2 2 0 Membrane-integrating protein Mistic Pex14_N PF04695.8 ETS79456.1 - 8.9e-20 71.1 0.2 1.9e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 ETS79456.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RecX family PAPA-1 PF04795.7 ETS79457.1 - 5.2e-24 84.7 5.8 5.2e-24 84.7 4.0 2.9 3 0 0 3 3 3 1 PAPA-1-like conserved region Rgp1 PF08737.5 ETS79458.1 - 3.2e-123 411.8 0.0 2.4e-122 409.0 0.0 1.9 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 ETS79458.1 - 0.006 16.4 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 ETS79458.1 - 0.014 15.5 0.0 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.27 ETS79459.1 - 8.3e-14 50.8 17.7 0.0031 17.3 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat PQQ_2 PF13360.1 ETS79459.1 - 0.0052 16.2 1.0 0.12 11.8 0.0 3.3 4 0 0 4 4 4 1 PQQ-like domain Neugrin PF06413.6 ETS79460.1 - 1.1e-10 41.7 2.1 1.2e-10 41.5 0.3 1.9 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 ETS79460.1 - 1.7e-06 28.0 7.1 2.4e-06 27.6 3.9 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 ETS79460.1 - 0.0098 16.0 0.3 0.042 13.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix DUF2236 PF09995.4 ETS79461.1 - 4.1e-36 124.5 0.0 6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) BPL_LplA_LipB PF03099.14 ETS79464.1 - 1.3e-14 54.2 0.0 3.8e-14 52.7 0.0 1.8 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 ETS79465.1 - 1.3e-128 428.3 0.0 1.5e-128 428.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Prenyltransf PF01255.14 ETS79467.1 - 2e-86 288.7 0.0 2.8e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 ETS79468.1 - 1.7e-09 37.1 7.9 3e-09 36.4 5.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 ETS79468.1 - 1.1e-06 28.8 0.1 1.1e-06 28.8 0.1 2.4 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Kisspeptin PF15152.1 ETS79468.1 - 0.023 15.3 1.3 0.023 15.3 0.9 4.5 4 1 0 5 5 5 0 Kisspeptin LRR_6 PF13516.1 ETS79469.1 - 0.015 15.3 0.0 1.5 9.1 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.2 ETS79469.1 - 0.022 14.3 0.5 1.1 8.9 0.0 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS79469.1 - 0.035 14.1 0.6 11 6.5 0.0 4.7 3 2 1 4 4 4 0 Leucine Rich Repeat V_ATPase_I PF01496.14 ETS79470.1 - 3e-302 1004.1 0.0 3.4e-302 1003.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IncA PF04156.9 ETS79470.1 - 0.0073 15.9 1.1 0.0073 15.9 0.7 2.7 3 0 0 3 3 3 1 IncA protein DUF869 PF05911.6 ETS79470.1 - 0.015 13.5 2.3 1.4 7.0 0.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 ETS79470.1 - 0.081 12.3 9.6 0.42 10.0 0.4 2.4 2 1 0 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 ETS79470.1 - 0.1 12.4 4.1 1.4 8.7 0.6 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 ETS79470.1 - 0.24 11.2 0.6 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TBPIP PF07106.8 ETS79470.1 - 0.63 9.5 5.1 4.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 ETS79470.1 - 6.3 6.3 6.0 1.6 8.2 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.8 ETS79470.1 - 7.6 6.4 8.7 3 7.7 1.2 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Sugar_tr PF00083.19 ETS79472.1 - 2.6e-109 365.8 20.2 3e-109 365.5 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79472.1 - 1.6e-25 89.5 24.9 1.6e-25 89.5 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 ETS79473.1 - 1.5e-40 138.9 39.2 1.5e-40 138.9 27.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79473.1 - 2.6e-16 59.2 14.2 3.7e-15 55.4 9.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Git3_C PF11970.3 ETS79473.1 - 0.38 10.5 2.7 1.6 8.5 0.5 2.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1751 PF08551.5 ETS79474.1 - 1.6e-05 25.1 0.9 2.9e-05 24.2 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 ETS79474.1 - 0.041 13.9 7.2 0.021 14.8 3.3 1.7 2 0 0 2 2 2 0 Rhomboid family Uds1 PF15456.1 ETS79475.1 - 6e-39 132.8 7.4 6e-39 132.8 5.1 7.1 5 1 1 6 6 6 2 Up-regulated During Septation Laminin_II PF06009.7 ETS79475.1 - 0.0011 18.7 4.8 0.0011 18.7 3.4 6.6 5 1 2 7 7 7 1 Laminin Domain II HR1 PF02185.11 ETS79475.1 - 0.0043 16.7 0.4 0.0043 16.7 0.3 8.6 6 3 2 8 8 8 2 Hr1 repeat Filament PF00038.16 ETS79475.1 - 0.54 9.6 78.0 0.012 15.0 4.1 5.6 4 2 0 4 4 4 0 Intermediate filament protein Reo_sigmaC PF04582.7 ETS79475.1 - 2.1 7.4 28.2 0.07 12.2 1.9 4.9 3 2 2 5 5 5 0 Reovirus sigma C capsid protein Glyco_transf_90 PF05686.7 ETS79476.1 - 1e-17 63.9 1.1 1.6e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Zn_clus PF00172.13 ETS79477.1 - 2.4e-07 30.5 11.5 3.7e-07 29.9 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS79477.1 - 0.16 10.5 0.0 0.3 9.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain ORC5_C PF14630.1 ETS79478.1 - 1.6e-70 237.6 0.0 2.7e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 ETS79478.1 - 1.3e-10 41.5 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 ETS79478.1 - 0.034 12.7 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Alpha-amylase_C PF02806.13 ETS79479.1 - 2.5e-28 98.0 0.1 5.5e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 ETS79479.1 - 2e-19 70.1 0.2 2.7e-15 56.5 0.1 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 ETS79479.1 - 4.2e-15 55.5 0.0 1.5e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 ETS79479.1 - 0.12 11.3 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme AAA_2 PF07724.9 ETS79480.1 - 9e-33 113.5 0.0 3.3e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETS79480.1 - 2.3e-12 47.2 0.2 5.4e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 ETS79480.1 - 2.2e-08 33.8 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 ETS79480.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS79480.1 - 0.00018 21.5 0.0 0.0049 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS79480.1 - 0.00088 19.4 0.3 0.0039 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS79480.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETS79480.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 ETS79480.1 - 0.0064 17.3 0.5 0.022 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain MCM PF00493.18 ETS79480.1 - 0.016 14.0 1.2 0.08 11.7 0.0 2.0 2 0 0 2 2 2 0 MCM2/3/5 family Mg_chelatase PF01078.16 ETS79480.1 - 0.094 11.8 0.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 ETS79480.1 - 0.23 11.2 1.2 3 7.6 0.0 2.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit COX4 PF02936.9 ETS79481.1 - 6.5e-49 165.3 0.2 7.6e-49 165.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 ETS79481.1 - 0.042 13.9 0.8 0.092 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) NUDIX_4 PF14815.1 ETS79482.1 - 4.5e-19 67.9 0.0 8.9e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 ETS79482.1 - 1.8e-18 66.8 0.0 3.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS79482.1 - 0.00087 18.8 0.5 0.0033 17.0 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DnaA_N PF11638.3 ETS79482.1 - 0.14 11.7 0.2 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain EndIII_4Fe-2S PF10576.4 ETS79482.1 - 8.8 6.6 9.5 18 5.6 6.6 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III bZIP_2 PF07716.10 ETS79483.1 - 2.1e-05 24.2 11.1 4.3e-05 23.2 7.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS79483.1 - 0.001 18.9 12.1 0.0016 18.3 8.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF3827 PF12877.2 ETS79483.1 - 0.32 9.0 3.1 0.43 8.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Protoglobin PF11563.3 ETS79484.1 - 8.1e-57 191.2 0.1 9.7e-57 191.0 0.1 1.1 1 0 0 1 1 1 1 Protoglobin HECT PF00632.20 ETS79485.1 - 9.3e-78 261.5 0.0 1.3e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GFA PF04828.9 ETS79486.1 - 2.9e-11 43.1 0.1 4e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Kp4 PF09044.5 ETS79486.1 - 0.11 12.3 0.7 0.23 11.2 0.1 1.7 1 1 1 2 2 2 0 Kp4 DGF-1_C PF11040.3 ETS79487.1 - 0.55 10.1 2.9 0.53 10.2 0.3 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus dCMP_cyt_deam_1 PF00383.17 ETS79488.1 - 7.9e-09 35.1 0.1 1e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4267 PF14087.1 ETS79489.1 - 3.4e-26 91.0 3.1 4.2e-26 90.7 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MgtE PF01769.11 ETS79490.1 - 0.59 10.4 8.0 0.51 10.6 4.9 1.4 1 1 0 1 1 1 0 Divalent cation transporter Asp_protease_2 PF13650.1 ETS79492.1 - 0.00075 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 ETS79492.1 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DiS_P_DiS PF06750.8 ETS79494.1 - 0.016 14.9 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Dehydrin PF00257.14 ETS79494.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.9 2 1 1 3 3 3 0 Dehydrin MFS_1 PF07690.11 ETS79495.1 - 6.3e-42 143.5 51.5 1.6e-41 142.2 33.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS79495.1 - 5.5e-19 67.8 12.8 5.5e-19 67.8 8.9 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS79495.1 - 4.5e-13 48.5 11.8 4.5e-13 48.5 8.2 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1700 PF08006.6 ETS79495.1 - 0.055 12.7 0.1 0.055 12.7 0.1 3.4 2 1 3 5 5 5 0 Protein of unknown function (DUF1700) Glyco_hydro_17 PF00332.13 ETS79497.1 - 6.8e-08 31.8 0.9 1.7e-07 30.6 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 ETS79497.1 - 0.023 13.5 0.2 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 PFO_beta_C PF12367.3 ETS79497.1 - 0.11 12.3 1.0 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Clr5 PF14420.1 ETS79498.1 - 3.8e-19 68.3 1.6 8.5e-19 67.2 1.1 1.6 1 0 0 1 1 1 1 Clr5 domain Acyl_transf_2 PF02273.10 ETS79498.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Acyl transferase SnoaL_2 PF12680.2 ETS79499.1 - 2.7e-06 27.7 0.0 7.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 ETS79499.1 - 0.00014 21.4 0.0 0.00033 20.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase YL1 PF05764.8 ETS79499.1 - 0.00088 18.9 10.6 0.0013 18.3 7.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF2890 PF11081.3 ETS79499.1 - 0.28 11.2 11.5 0.17 11.9 6.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 ETS79499.1 - 0.62 9.2 10.6 0.87 8.7 7.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS79499.1 - 1.9 6.3 14.4 2.7 5.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family UFD1 PF03152.9 ETS79500.1 - 7.1e-69 230.4 0.0 9e-69 230.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.11 ETS79501.1 - 1.5e-10 40.4 1.4 3e-10 39.5 0.5 1.8 2 0 0 2 2 2 1 GYF domain Ribosomal_S30 PF04758.9 ETS79501.1 - 1.4 8.6 8.6 6.2 6.6 3.3 2.7 2 0 0 2 2 2 0 Ribosomal protein S30 BAF1_ABF1 PF04684.8 ETS79502.1 - 0.11 11.3 8.5 0.089 11.6 4.6 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 ETS79503.1 - 0.0001 21.1 0.3 0.00011 21.0 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BNR_2 PF13088.1 ETS79504.1 - 0.023 13.9 0.2 0.024 13.9 0.2 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Tim54 PF11711.3 ETS79505.1 - 0.093 11.3 1.6 0.13 10.8 1.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EthD PF07110.6 ETS79506.1 - 0.09 13.7 2.2 0.12 13.3 0.6 1.9 1 1 1 2 2 2 0 EthD domain TLP-20 PF06088.6 ETS79506.1 - 0.12 12.0 0.7 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) F-protein PF00469.15 ETS79507.1 - 0.026 13.9 2.5 0.034 13.5 1.7 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Sec62 PF03839.11 ETS79507.1 - 2.9 7.2 7.8 4.6 6.5 5.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 YfdX PF10938.3 ETS79508.1 - 0.0024 17.5 0.2 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 YfdX protein Maf PF02545.9 ETS79508.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Maf-like protein MFS_1 PF07690.11 ETS79509.1 - 2.2e-23 82.5 59.1 2.1e-22 79.3 20.0 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79509.1 - 1.7e-05 23.6 27.0 7.6e-05 21.4 2.8 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter NmrA PF05368.8 ETS79510.1 - 1.8e-13 50.2 0.0 2.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS79510.1 - 1.6e-09 38.0 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS79510.1 - 0.051 13.8 0.2 0.36 11.1 0.1 2.4 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain EIIBC-GUT_N PF03612.9 ETS79510.1 - 0.053 13.1 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus adh_short PF00106.20 ETS79511.1 - 4.5e-15 55.9 0.1 7.8e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79511.1 - 3.5e-08 33.3 0.1 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS79511.1 - 0.0052 16.2 0.1 0.013 14.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS79511.1 - 0.045 13.7 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding TerB-C PF15615.1 ETS79511.1 - 0.062 13.5 0.2 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 TerB-C domain C1_2 PF03107.11 ETS79512.1 - 0.01 15.9 6.6 0.019 15.0 4.6 1.5 1 0 0 1 1 1 0 C1 domain ZZ PF00569.12 ETS79512.1 - 0.074 12.6 5.9 0.17 11.4 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_1 PF00130.17 ETS79512.1 - 0.77 9.5 4.4 1.8 8.3 3.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HIT PF04438.11 ETS79512.1 - 2 8.1 4.6 12 5.6 3.3 2.1 1 1 1 2 2 2 0 HIT zinc finger Histone_HNS PF00816.16 ETS79514.1 - 0.9 10.0 4.1 1.4 9.4 0.3 2.4 2 1 0 2 2 2 0 H-NS histone family BSP_II PF05432.6 ETS79514.1 - 5.8 6.0 10.6 11 5.2 7.3 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) OGFr_III PF04680.8 ETS79515.1 - 0.26 11.4 0.3 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Opioid growth factor receptor repeat LPP PF04728.8 ETS79516.1 - 0.0019 17.9 0.6 0.19 11.5 0.1 3.3 2 0 0 2 2 2 1 Lipoprotein leucine-zipper KfrA_N PF11740.3 ETS79516.1 - 0.34 11.3 7.8 2.4 8.5 0.6 3.3 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term WXG100 PF06013.7 ETS79516.1 - 0.75 9.8 6.3 5.7 7.0 0.2 4.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.7 ETS79516.1 - 0.87 9.8 11.2 1.8 8.8 0.8 3.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 ETS79516.1 - 1 9.1 22.4 1.9 8.2 12.8 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cpn60_TCP1 PF00118.19 ETS79518.1 - 2e-120 402.7 8.1 2.3e-120 402.5 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 ETS79519.1 - 2.4e-34 117.9 0.2 2.8e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Tenui_NCP PF04876.7 ETS79519.1 - 0.075 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein SpoVR PF04293.8 ETS79519.1 - 0.12 10.6 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein Blt1 PF12754.2 ETS79520.1 - 3e-41 142.0 2.5 2.3e-35 122.7 0.3 2.0 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 ETS79520.1 - 9.8e-08 31.2 0.3 1.7e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Nol1_Nop2_Fmu PF01189.12 ETS79521.1 - 1.2e-97 326.7 0.0 2.9e-96 322.1 0.0 2.2 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 ETS79521.1 - 0.0081 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 ETS79521.1 - 0.027 13.4 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.14 ETS79521.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4419 PF14388.1 ETS79523.1 - 2.2e-77 260.2 0.0 2.8e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF3176 PF11374.3 ETS79526.1 - 2.3e-38 130.5 1.0 6.8e-38 128.9 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) COesterase PF00135.23 ETS79527.1 - 4.3e-105 352.4 0.0 5.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS79527.1 - 0.00025 20.6 0.0 0.0011 18.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_4 PF13147.1 ETS79528.1 - 1.1e-26 94.5 0.3 2.1e-23 83.7 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 ETS79528.1 - 2.9e-14 53.4 1.2 7.3e-13 48.8 0.9 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS79528.1 - 2.2e-11 43.3 4.8 2.3e-11 43.3 1.7 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS79528.1 - 5.6e-08 32.4 0.3 0.0015 17.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family GFA PF04828.9 ETS79529.1 - 1.3e-20 73.0 0.1 2.1e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PAP2 PF01569.16 ETS79532.1 - 9.4e-21 73.8 4.0 9.4e-21 73.8 2.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF983 PF06170.7 ETS79532.1 - 0.036 14.1 0.1 0.036 14.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF983) TPPK_C PF12555.3 ETS79532.1 - 0.055 13.2 0.8 0.055 13.2 0.5 3.0 4 0 0 4 4 4 0 Thiamine pyrophosphokinase C terminal Rhomboid PF01694.17 ETS79532.1 - 0.33 10.9 8.4 0.033 14.2 1.1 2.2 2 0 0 2 2 2 0 Rhomboid family XRCC4 PF06632.7 ETS79534.1 - 0.00017 20.5 31.2 0.0041 16.0 21.6 2.1 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF507 PF04368.8 ETS79534.1 - 0.024 14.2 2.6 0.049 13.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DivIC PF04977.10 ETS79534.1 - 0.49 9.9 7.1 0.071 12.5 1.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 ETS79534.1 - 6 5.7 10.9 8.8 5.1 7.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Aldo_ket_red PF00248.16 ETS79535.1 - 1e-55 188.6 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2774 PF11242.3 ETS79535.1 - 0.073 13.0 0.1 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_AsnC-type PF13404.1 ETS79535.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain UPF0061 PF02696.9 ETS79536.1 - 7.3e-123 410.4 0.0 8.9e-123 410.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.17 ETS79537.1 - 3.3e-69 233.6 0.0 2.3e-67 227.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 ETS79537.1 - 1.9e-18 65.3 0.1 4.8e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 ETS79537.1 - 8.8e-16 57.7 0.0 2.5e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 ETS79537.1 - 2.6e-14 52.7 0.5 3.6e-13 49.1 0.3 2.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 ETS79537.1 - 0.024 14.3 3.2 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Striatin PF08232.7 ETS79538.1 - 2.4e-36 125.0 1.9 4.7e-36 124.0 1.3 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 ETS79538.1 - 9.3e-31 104.5 16.4 2.2e-07 30.5 0.1 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS79538.1 - 0.11 10.7 0.0 0.39 8.9 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Hce2 PF14856.1 ETS79539.1 - 1.5e-07 31.2 0.1 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF726 PF05277.7 ETS79540.1 - 1.9e-82 276.9 0.0 2.9e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3046 PF11248.3 ETS79540.1 - 0.049 13.6 0.1 0.62 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) COesterase PF00135.23 ETS79540.1 - 0.087 11.5 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family Gate PF07670.9 ETS79540.1 - 0.1 12.5 0.1 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoside recognition Abhydrolase_6 PF12697.2 ETS79540.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glu-tRNAGln PF02686.10 ETS79541.1 - 2.9e-05 23.7 0.0 0.00013 21.6 0.0 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.1 ETS79542.1 - 1.3e-113 378.8 14.9 1.4e-113 378.7 10.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 ETS79542.1 - 0.0016 18.3 9.6 0.47 10.4 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF2521 PF10730.4 ETS79542.1 - 0.051 13.3 0.7 0.098 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) TPR_7 PF13176.1 ETS79542.1 - 0.15 11.9 5.8 3.2 7.7 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS79542.1 - 0.19 11.3 9.1 6 6.6 0.1 5.3 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETS79542.1 - 1.2 8.8 15.3 2.3 7.9 0.4 3.3 1 1 3 4 4 4 0 TPR repeat NUC173 PF08161.7 ETS79544.1 - 1.6e-77 259.3 0.0 9.3e-75 250.3 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 ETS79544.1 - 0.022 14.8 1.8 8.5 6.7 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat V-SNARE PF05008.10 ETS79545.1 - 1.7e-22 79.3 2.0 1.7e-22 79.3 1.4 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 ETS79545.1 - 2.2e-16 59.6 1.2 2.2e-16 59.6 0.8 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF3526 PF12040.3 ETS79545.1 - 0.015 15.4 3.9 0.14 12.2 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3526) Laminin_I PF06008.9 ETS79545.1 - 0.019 14.2 0.9 0.019 14.2 0.6 2.1 2 1 0 2 2 2 0 Laminin Domain I YvbH_ext PF11724.3 ETS79545.1 - 0.024 14.2 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Amino_oxidase PF01593.19 ETS79546.1 - 1.1e-11 44.5 1.1 2.5e-09 36.7 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS79546.1 - 1.6e-10 40.8 0.2 3.5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS79546.1 - 5.9e-05 23.2 0.3 0.0058 16.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS79546.1 - 8.1e-05 22.4 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 ETS79546.1 - 0.00017 20.6 0.6 0.0068 15.3 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS79546.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 ETS79546.1 - 0.0043 15.5 0.0 0.76 8.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 ETS79546.1 - 0.013 15.4 0.1 0.089 12.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS79546.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family CtaG_Cox11 PF04442.9 ETS79547.1 - 1.7e-57 193.4 0.0 2.4e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 FNIP_N PF14636.1 ETS79547.1 - 0.012 16.0 0.4 0.019 15.4 0.3 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FA_desaturase PF00487.19 ETS79548.1 - 4.9 6.5 10.4 0.64 9.4 3.9 1.8 1 1 1 2 2 2 0 Fatty acid desaturase Peptidase_M35 PF02102.10 ETS79551.1 - 0.00015 20.5 0.0 0.057 12.0 0.0 2.1 2 0 0 2 2 2 2 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 ETS79551.1 - 0.022 14.1 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase family VWA PF00092.23 ETS79553.1 - 1.8e-10 40.8 0.0 3.5e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETS79553.1 - 6.2e-07 29.6 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Rnk_N PF14760.1 ETS79554.1 - 0.088 12.8 2.6 0.28 11.2 0.0 2.8 3 0 0 3 3 3 0 Rnk N-terminus IncA PF04156.9 ETS79554.1 - 0.12 11.9 13.8 0.2 11.2 9.6 1.3 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 ETS79554.1 - 4.6 6.2 10.1 7.3 5.5 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF572 PF04502.8 ETS79554.1 - 5.4 6.1 14.6 9.2 5.3 10.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tup_N PF08581.5 ETS79554.1 - 6.1 7.1 17.0 0.62 10.2 6.1 2.4 1 1 1 2 2 2 0 Tup N-terminal V_ATPase_I PF01496.14 ETS79554.1 - 7 4.3 11.1 9.9 3.8 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 ETS79554.1 - 8.8 6.2 20.2 9.7 6.0 11.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.17 ETS79555.1 - 1.4e-44 149.5 1.3 3e-20 71.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79555.1 - 2.1e-35 120.5 0.1 3.6e-18 65.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 ETS79555.1 - 1.1e-25 89.6 0.1 2.8e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 ETS79555.1 - 2.6e-21 75.2 0.0 1.2e-08 34.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS79555.1 - 0.0005 19.8 0.2 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif Phytase-like PF13449.1 ETS79556.1 - 8e-27 94.3 0.0 1.4e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase HET PF06985.6 ETS79557.1 - 4.3e-33 114.4 0.4 1.2e-32 112.9 0.2 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CRM1_C PF08767.6 ETS79558.1 - 3.9e-127 423.5 0.1 3.9e-127 423.5 0.0 3.0 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 ETS79558.1 - 1.8e-40 138.2 11.9 3.1e-40 137.5 5.2 3.4 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 ETS79558.1 - 1.4e-13 50.5 0.1 6.4e-13 48.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 ETS79558.1 - 0.014 15.3 0.3 0.15 12.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) C8 PF08742.6 ETS79558.1 - 0.082 13.1 0.3 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 C8 domain HD_assoc PF13286.1 ETS79558.1 - 0.09 13.0 0.4 55 4.1 0.2 4.3 5 0 0 5 5 5 0 Phosphohydrolase-associated domain Aminotran_5 PF00266.14 ETS79559.1 - 2.9e-26 92.0 0.0 3.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 ETS79559.1 - 1.9e-05 23.8 0.0 3.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 ETS79559.1 - 0.00011 22.0 0.1 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain DUF521 PF04412.8 ETS79559.1 - 0.034 12.6 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Cys_Met_Meta_PP PF01053.15 ETS79559.1 - 0.072 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HEM4 PF02602.10 ETS79559.1 - 0.08 12.1 0.0 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Metallophos_2 PF12850.2 ETS79560.1 - 1e-12 48.1 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETS79560.1 - 0.12 11.7 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Shugoshin_N PF07558.6 ETS79561.1 - 4.6e-14 51.8 4.4 8.6e-14 50.9 3.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 ETS79561.1 - 2e-09 36.7 4.5 2e-09 36.7 3.1 3.0 2 0 0 2 2 2 1 Shugoshin C terminus DASH_Dad2 PF08654.5 ETS79562.1 - 2.5e-35 120.5 1.1 2.5e-35 120.5 0.7 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 ETS79562.1 - 0.00074 19.5 2.1 0.0015 18.5 0.2 2.3 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain IFT20 PF14931.1 ETS79562.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HAUS2 PF15003.1 ETS79562.1 - 0.03 13.3 0.1 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 NPV_P10 PF05531.7 ETS79562.1 - 0.039 14.1 2.2 0.13 12.5 0.5 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 ETS79562.1 - 0.047 12.7 0.2 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 ETS79562.1 - 0.12 12.1 1.3 14 5.5 0.4 2.6 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 ETS79562.1 - 0.38 10.5 4.2 0.3 10.9 1.9 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 ETS79562.1 - 0.46 10.4 5.9 0.54 10.2 2.5 2.2 2 1 0 2 2 2 0 FlxA-like protein DivIC PF04977.10 ETS79562.1 - 4.7 6.7 5.8 25 4.4 1.9 2.6 2 1 1 3 3 3 0 Septum formation initiator COesterase PF00135.23 ETS79564.1 - 8.3e-88 295.4 0.0 1.2e-87 294.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS79564.1 - 2.8e-05 23.7 0.6 0.00016 21.3 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79564.1 - 0.034 13.8 0.2 0.09 12.5 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family TAF4 PF05236.9 ETS79565.1 - 6.3e-11 42.0 0.1 8.8e-09 35.0 0.0 3.5 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family CDK2AP PF09806.4 ETS79565.1 - 0.023 14.9 0.6 0.023 14.9 0.4 3.6 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CPSF73-100_C PF11718.3 ETS79566.1 - 2e-75 252.8 0.0 4.4e-73 245.2 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 ETS79566.1 - 3.2e-31 107.8 0.0 7.1e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 ETS79566.1 - 4.2e-14 52.6 1.7 1.1e-13 51.2 1.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS79566.1 - 1.3e-12 47.6 0.7 2.5e-12 46.7 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 ETS79566.1 - 1.6e-09 37.4 0.1 4e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 ETS79566.1 - 4.5e-06 26.4 0.2 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VWA_2 PF13519.1 ETS79567.1 - 0.02 14.9 1.5 0.13 12.3 1.1 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain HSF_DNA-bind PF00447.12 ETS79569.1 - 1.7e-35 121.2 0.9 3.2e-35 120.4 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding WD40 PF00400.27 ETS79570.1 - 2.3e-25 87.4 3.8 1.3e-08 34.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 ETS79570.1 - 2.1e-08 33.9 2.2 2.1e-08 33.9 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 ETS79570.1 - 2.2e-05 23.4 0.0 5e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 ETS79570.1 - 4.8e-05 23.1 0.2 0.12 12.1 0.1 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 ETS79570.1 - 0.0017 18.0 1.2 0.0038 16.9 0.8 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 ETS79570.1 - 0.013 13.3 0.0 0.024 12.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.7 ETS79570.1 - 0.02 14.5 0.1 70 3.2 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MRJP PF03022.11 ETS79570.1 - 0.037 13.2 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 Major royal jelly protein WD40 PF00400.27 ETS79571.1 - 1.8e-20 72.0 11.3 0.0003 20.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 ETS79571.1 - 0.003 15.7 1.4 0.78 7.7 0.0 2.6 3 1 0 3 3 3 2 Nucleoporin Nup120/160 SGL PF08450.7 ETS79571.1 - 0.026 13.8 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Ank_2 PF12796.2 ETS79572.1 - 6.4e-34 116.1 3.1 4.5e-11 42.9 0.1 5.4 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS79572.1 - 6.3e-27 93.0 7.4 2.6e-08 33.8 0.2 6.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS79572.1 - 5.9e-25 87.1 6.0 0.0011 19.4 0.0 7.7 5 2 3 8 8 7 5 Ankyrin repeats (many copies) Ank PF00023.25 ETS79572.1 - 9.2e-23 78.8 19.2 5.8e-07 29.0 0.1 8.3 7 2 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 ETS79572.1 - 1.5e-18 65.0 5.2 0.0083 16.2 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.7 ETS79572.1 - 1.7e-09 37.5 0.1 3.3e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS79572.1 - 2.2e-06 27.8 0.0 5.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 ETS79572.1 - 0.00012 21.1 2.0 0.27 10.2 0.7 2.3 2 0 0 2 2 2 2 KAP family P-loop domain ABC_tran PF00005.22 ETS79572.1 - 0.0038 17.5 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 ETS79572.1 - 0.004 17.2 0.8 0.0078 16.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.1 ETS79572.1 - 0.0042 17.0 0.1 0.018 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 ETS79572.1 - 0.0046 17.7 0.7 0.033 14.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 ETS79572.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS79572.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 ETS79572.1 - 0.046 14.0 0.1 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS79572.1 - 0.059 12.2 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 ETS79572.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 ETS79572.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 ETS79572.1 - 0.16 11.6 0.0 0.74 9.4 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase Pkinase PF00069.20 ETS79574.1 - 1.4e-70 237.4 0.0 2.2e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79574.1 - 3.5e-30 104.9 0.0 5.4e-29 101.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS79574.1 - 2.1e-05 23.6 0.2 0.0036 16.3 0.0 3.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS79574.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS79574.1 - 0.054 13.2 0.6 1.7 8.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family AT_hook PF02178.14 ETS79575.1 - 0.2 11.4 19.3 0.67 9.8 2.7 2.8 2 0 0 2 2 2 0 AT hook motif zf-C2H2_4 PF13894.1 ETS79575.1 - 2 8.9 5.8 33 5.1 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CCCH PF00642.19 ETS79576.1 - 1.2e-05 24.7 0.8 1.2e-05 24.7 0.5 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 ETS79577.1 - 1e-16 60.3 0.0 1.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79577.1 - 5.7e-12 45.4 0.0 8.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79577.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 ETS79577.1 - 4.7e-05 23.7 1.8 4.7e-05 23.7 1.2 3.1 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 LZ_Tnp_IS481 PF13011.1 ETS79577.1 - 0.14 12.5 1.1 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 MRI PF15325.1 ETS79577.1 - 2.2 9.2 4.6 1.2 10.1 1.0 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF3438 PF11920.3 ETS79578.1 - 0.13 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Mito_fiss_reg PF05308.6 ETS79578.1 - 5 6.4 8.6 0.72 9.1 2.8 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Reprolysin_5 PF13688.1 ETS79579.1 - 5.6e-58 196.1 9.3 5.6e-58 196.1 6.5 2.8 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 ETS79579.1 - 4.8e-49 166.6 3.1 8.4e-49 165.8 2.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETS79579.1 - 9.3e-47 159.2 4.8 1.7e-46 158.4 2.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETS79579.1 - 1.5e-18 67.5 0.4 1.5e-18 67.5 0.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 ETS79579.1 - 1.6e-17 63.5 35.9 1.6e-17 63.5 24.9 4.7 2 2 2 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 ETS79579.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide DNA_pol_E_B PF04042.11 ETS79581.1 - 2e-50 170.9 0.0 2.8e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B WD40 PF00400.27 ETS79582.1 - 5.7e-36 121.1 13.1 1.5e-09 37.3 0.7 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 ETS79582.1 - 1.7e-19 69.5 0.1 2.7e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 ETS79582.1 - 0.0011 17.1 1.8 0.056 11.5 0.3 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.15 ETS79583.1 - 2.1e-15 56.6 0.0 3.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF2316 PF10078.4 ETS79583.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) RNA_pol_L_2 PF13656.1 ETS79584.1 - 5.1e-23 80.2 0.0 7.2e-23 79.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 ETS79584.1 - 1.9e-08 33.2 0.0 2.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AA_permease PF00324.16 ETS79585.1 - 6.5e-60 202.8 29.7 7.9e-60 202.5 20.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS79585.1 - 2.4e-13 49.4 34.3 4e-13 48.6 23.8 1.3 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 ETS79586.1 - 3.7e-81 272.6 39.2 4.5e-81 272.4 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CorA PF01544.13 ETS79588.1 - 2.6e-11 43.0 2.9 2.6e-11 43.0 2.0 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Methyltransf_2 PF00891.13 ETS79589.1 - 8.8e-32 110.2 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 ETS79589.1 - 2.4e-05 24.0 0.2 5.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 ETS79589.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Spt4 PF06093.8 ETS79591.1 - 1.6e-32 111.2 0.3 1.9e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 ETS79591.1 - 0.064 13.0 0.3 0.084 12.7 0.2 1.2 1 0 0 1 1 1 0 RNHCP domain Coronavirus_5 PF05528.6 ETS79591.1 - 0.18 11.6 0.6 1.6 8.6 0.1 2.1 1 1 1 2 2 2 0 Coronavirus gene 5 protein Metallophos PF00149.23 ETS79593.1 - 6.3e-39 133.4 0.1 9.8e-39 132.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 ETS79593.1 - 3.8e-30 103.7 3.4 4.8e-30 103.4 0.8 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 ETS79593.1 - 3.3e-27 93.9 8.5 1e-17 63.5 0.9 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETS79593.1 - 4e-18 64.1 2.8 1.1e-05 24.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS79593.1 - 2.5e-14 51.9 1.7 0.0011 18.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS79593.1 - 2.4e-08 33.5 2.6 0.0016 18.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS79593.1 - 7.7e-06 26.4 0.5 0.18 12.5 1.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS79593.1 - 4.2e-05 23.8 0.1 0.54 11.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS79593.1 - 7.4e-05 23.0 0.8 0.9 9.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS79593.1 - 0.00023 20.9 0.0 0.11 12.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS79593.1 - 0.0073 16.2 0.1 0.41 10.6 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS79593.1 - 0.015 15.0 1.0 3.5 7.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS79593.1 - 0.087 12.9 1.2 0.27 11.3 0.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos_2 PF12850.2 ETS79593.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UPF0029 PF01205.14 ETS79594.1 - 8.7e-31 105.8 0.0 1.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 ETS79594.1 - 3.3e-11 43.0 0.0 5.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 ETS79594.1 - 0.035 13.5 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme CoA_transf_3 PF02515.12 ETS79595.1 - 7.7e-53 178.5 0.1 1.1e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DNMT1-RFD PF12047.3 ETS79596.1 - 0.032 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.13 ETS79597.1 - 5.3e-45 153.2 0.2 1.6e-44 151.6 0.0 1.8 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF2486 PF10667.4 ETS79597.1 - 0.019 15.5 4.2 0.019 15.5 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) ERG2_Sigma1R PF04622.7 ETS79598.1 - 2.6e-97 324.2 0.3 3e-97 324.1 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.4 ETS79599.1 - 6.4e-31 106.1 0.6 9.5e-31 105.5 0.4 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 ETS79599.1 - 2.6e-14 52.2 0.0 5.7e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 ETS79599.1 - 0.017 15.2 0.1 0.2 11.7 0.1 2.2 1 1 0 1 1 1 0 S1 RNA binding domain Sec2p PF06428.6 ETS79600.1 - 9.2e-10 38.2 11.4 1.6e-09 37.4 5.9 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 ETS79600.1 - 0.0002 20.9 3.3 0.04 13.5 1.6 2.1 2 0 0 2 2 2 2 IncA protein SlyX PF04102.7 ETS79600.1 - 0.0074 16.6 11.8 0.12 12.8 0.4 3.2 3 0 0 3 3 3 2 SlyX Vac_Fusion PF02346.11 ETS79600.1 - 0.5 9.8 2.9 2.7 7.5 1.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Latarcin PF10279.4 ETS79600.1 - 1.1 9.4 5.6 2.2 8.5 3.9 1.5 1 0 0 1 1 1 0 Latarcin precursor MbeD_MobD PF04899.7 ETS79600.1 - 1.3 8.9 6.8 8.9 6.3 1.5 3.3 2 1 1 3 3 3 0 MbeD/MobD like Prefoldin_2 PF01920.15 ETS79600.1 - 5.2 6.8 9.6 1.1 9.0 2.2 2.5 3 0 0 3 3 3 0 Prefoldin subunit MKT1_C PF12246.3 ETS79601.1 - 5.8e-62 208.8 0.0 7.8e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 ETS79601.1 - 2.6e-26 91.7 0.2 7.1e-26 90.3 0.1 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 ETS79601.1 - 0.0002 21.5 0.0 0.00061 20.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain DUF4048 PF13257.1 ETS79602.1 - 1.4e-18 67.4 30.0 1.2e-16 61.0 4.5 4.7 2 1 3 5 5 5 4 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.16 ETS79603.1 - 6e-21 74.7 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETS79603.1 - 6.2e-15 55.4 0.0 2.4e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus Glyco_transf_41 PF13844.1 ETS79603.1 - 0.11 10.4 0.0 0.27 9.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 41 DIOX_N PF14226.1 ETS79604.1 - 1.3e-20 74.0 0.0 2.1e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS79604.1 - 8.9e-14 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_ab PF00006.20 ETS79605.1 - 3.9e-113 376.2 0.0 6.4e-113 375.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS79605.1 - 2.4e-17 63.4 1.1 4.7e-17 62.4 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS79605.1 - 2.1e-14 53.5 3.3 1e-13 51.2 2.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Ferritin_2 PF13668.1 ETS79606.1 - 1.6e-41 141.4 0.4 2.5e-41 140.8 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain RNB PF00773.14 ETS79607.1 - 6.5e-73 245.8 0.0 1.2e-72 244.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 ETS79607.1 - 0.18 11.1 0.1 0.37 10.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Epsilon_antitox PF08998.6 ETS79607.1 - 0.3 11.0 1.3 0.88 9.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial epsilon antitoxin DUF2072 PF09845.4 ETS79607.1 - 1.7 8.5 6.3 9.7 6.1 0.3 2.8 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) GLE1 PF07817.8 ETS79608.1 - 8.3e-24 83.9 0.0 2.2e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 GLE1-like protein Macoilin PF09726.4 ETS79608.1 - 0.0052 15.1 0.3 0.0052 15.1 0.2 2.1 1 1 0 2 2 2 1 Transmembrane protein DUF972 PF06156.8 ETS79608.1 - 5.6 7.3 8.4 3.5 8.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 ETS79609.1 - 6.7e-26 90.5 0.4 2.7e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 ETS79609.1 - 6e-10 38.6 5.1 6e-10 38.6 3.6 2.3 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.6 ETS79609.1 - 0.0074 13.8 0.2 0.012 13.2 0.1 1.4 1 1 0 1 1 1 1 Prominin AATF-Che1 PF13339.1 ETS79609.1 - 0.022 14.9 1.2 0.047 13.8 0.1 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Rifin_STEVOR PF02009.11 ETS79609.1 - 0.083 12.5 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Rifin/stevor family TBPIP PF07106.8 ETS79609.1 - 0.25 10.8 1.6 2.1 7.8 0.0 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 ETS79609.1 - 0.31 11.3 2.3 0.72 10.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF745 PF05335.8 ETS79609.1 - 0.61 9.5 11.9 0.39 10.2 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) WEMBL PF05701.6 ETS79609.1 - 0.85 8.0 9.5 2.7 6.3 2.3 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Histone_HNS PF00816.16 ETS79609.1 - 2 8.9 4.6 2.5 8.6 0.3 2.8 2 2 0 2 2 2 0 H-NS histone family FlaC_arch PF05377.6 ETS79609.1 - 2.1 8.2 4.8 27 4.7 0.0 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) WXG100 PF06013.7 ETS79609.1 - 3.4 7.7 9.4 1.6 8.8 0.1 3.5 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Methyltransf_32 PF13679.1 ETS79610.1 - 1.5e-20 73.3 0.0 3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ACT_7 PF13840.1 ETS79611.1 - 2.7e-20 71.6 0.7 7.3e-17 60.6 0.0 2.5 2 0 0 2 2 2 2 ACT domain FA_desaturase PF00487.19 ETS79612.1 - 0.67 9.3 7.0 1.2 8.4 4.4 1.8 1 1 0 1 1 1 0 Fatty acid desaturase DUF3402 PF11882.3 ETS79613.1 - 9.4e-152 505.7 0.0 1.2e-151 505.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 ETS79613.1 - 6e-68 228.8 0.0 1.1e-67 227.9 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 ETS79614.1 - 5.2e-15 55.2 2.7 5.2e-15 55.2 1.9 1.6 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 ETS79614.1 - 0.022 14.4 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family MFS_1 PF07690.11 ETS79614.1 - 0.071 11.8 4.7 0.037 12.7 2.1 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 ETS79614.1 - 1.7 8.0 5.8 1.1 8.6 2.0 2.0 1 1 1 2 2 2 0 7TM receptor with intracellular HD hydrolase IBR PF01485.16 ETS79615.1 - 9.3e-22 76.6 36.2 1.7e-15 56.6 2.1 3.8 3 1 1 4 4 4 3 IBR domain RWD PF05773.17 ETS79615.1 - 1.9e-18 66.4 0.1 3.3e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 ETS79615.1 - 4.4e-05 23.2 7.4 4.4e-05 23.2 5.1 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 ETS79615.1 - 0.0011 18.6 5.3 0.0011 18.6 3.7 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS79615.1 - 0.0013 18.7 8.0 0.0013 18.7 5.6 4.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS79615.1 - 0.0096 15.6 3.0 0.0096 15.6 2.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 ETS79615.1 - 0.011 15.4 5.4 0.011 15.4 3.7 3.8 2 1 1 3 3 3 0 zinc-RING finger domain Baculo_RING PF05883.6 ETS79615.1 - 0.017 14.9 1.1 0.017 14.9 0.8 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain NDT80_PhoG PF05224.7 ETS79616.1 - 1.6e-32 113.0 0.0 1.3e-31 110.0 0.0 2.3 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 ETS79617.1 - 6.6e-25 87.4 15.0 2.7e-24 85.5 10.4 1.9 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) VGCC_beta4Aa_N PF12052.3 ETS79617.1 - 0.079 12.8 1.2 0.25 11.2 0.8 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Atg14 PF10186.4 ETS79617.1 - 0.98 8.2 8.8 1.4 7.7 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ank_2 PF12796.2 ETS79618.1 - 0.01 16.1 0.0 4.9 7.5 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (3 copies) PNP_UDP_1 PF01048.15 ETS79619.1 - 2.5e-05 23.3 0.0 2.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.13 ETS79620.1 - 8.7e-38 129.6 0.5 8.7e-38 129.6 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79620.1 - 4.1e-08 33.0 9.6 8e-08 32.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.16 ETS79621.1 - 1.7e-19 69.8 0.4 2.7e-19 69.2 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 ETS79621.1 - 1.5e-05 24.3 0.1 3.3e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS79621.1 - 1.7e-05 24.5 0.1 3.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS79621.1 - 4.3e-05 23.5 3.0 0.00057 19.8 1.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS79621.1 - 0.00055 19.4 0.1 0.28 10.5 0.1 2.5 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 ETS79621.1 - 0.042 13.5 0.1 1.9 8.1 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TRI12 PF06609.8 ETS79622.1 - 5.1e-62 209.9 23.6 6.7e-62 209.5 16.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS79622.1 - 5.4e-26 91.1 38.4 5.4e-26 91.1 26.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79622.1 - 1.9e-11 43.1 9.1 1.9e-11 43.1 6.3 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF4407 PF14362.1 ETS79623.1 - 0.76 8.6 4.8 0.8 8.5 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 ETS79623.1 - 8.4 6.7 8.9 0.8 10.0 2.1 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF3445 PF11927.3 ETS79624.1 - 8.8e-62 208.7 0.3 1.2e-61 208.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ctr PF04145.10 ETS79625.1 - 3.2e-44 150.4 0.1 3.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.14 ETS79626.1 - 1.4e-21 76.9 10.7 2.9e-21 75.8 7.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS79626.1 - 9.7e-21 74.2 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS79626.1 - 3.2e-10 39.8 0.0 1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 ETS79626.1 - 6.3e-10 39.5 0.0 1.5e-07 31.9 0.0 2.7 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain Abhydrolase_6 PF12697.2 ETS79627.1 - 3.1e-08 33.7 2.7 5.8e-08 32.8 1.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS79627.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79627.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 ETS79628.1 - 7.4e-12 44.9 0.1 2.3e-10 40.2 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS79628.1 - 3.1e-07 29.9 1.1 6.3e-07 28.9 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS79628.1 - 5.5e-05 24.0 0.6 0.00012 22.9 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MSP1b PF03429.8 ETS79628.1 - 0.068 11.0 0.4 0.093 10.6 0.3 1.1 1 0 0 1 1 1 0 Major surface protein 1B NAD_binding_10 PF13460.1 ETS79628.1 - 0.086 12.8 0.5 0.19 11.7 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding Tyrosinase PF00264.15 ETS79629.1 - 1.7e-48 165.6 2.5 2.9e-48 164.9 1.7 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Cytokin_check_N PF10407.4 ETS79629.1 - 0.064 12.8 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus BNR PF02012.15 ETS79630.1 - 1.6e-06 27.0 21.3 0.84 9.7 0.1 6.7 7 0 0 7 7 7 4 BNR/Asp-box repeat PSII_BNR PF14870.1 ETS79630.1 - 9.5e-06 24.8 5.2 0.0037 16.2 0.2 4.1 3 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 ETS79630.1 - 4.6 6.8 7.1 7.2 6.2 0.1 3.8 4 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain COG5 PF10392.4 ETS79631.1 - 0.03 14.2 0.8 0.12 12.3 0.1 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CorA PF01544.13 ETS79631.1 - 0.047 12.7 13.2 0.32 9.9 9.2 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.13 ETS79631.1 - 0.09 12.2 0.0 0.79 9.1 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain SKG6 PF08693.5 ETS79631.1 - 3.4 7.0 5.5 2.8 7.3 2.4 2.0 2 1 0 2 2 2 0 Transmembrane alpha-helix domain MFS_1 PF07690.11 ETS79632.1 - 2.6e-41 141.5 49.8 1.4e-33 116.0 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YscJ_FliF PF01514.12 ETS79632.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family SnoaL_2 PF12680.2 ETS79633.1 - 0.0027 18.1 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.21 ETS79634.1 - 1.8e-20 73.6 3.2 1.8e-20 73.6 2.2 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_S64 PF08192.6 ETS79634.1 - 1.6 6.9 7.7 1.8 6.7 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 ETS79634.1 - 7.6 5.4 8.1 8.7 5.2 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Cyclase PF04199.8 ETS79635.1 - 4.1e-11 42.8 0.0 5.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase CTDII PF01556.13 ETS79636.1 - 5.7e-16 58.1 0.0 5e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain Baculo_PEP_C PF04513.7 ETS79636.1 - 0.0061 16.3 1.3 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.13 ETS79636.1 - 0.012 15.3 0.2 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase EST1 PF10374.4 ETS79636.1 - 0.023 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 DUF2740 PF10872.3 ETS79636.1 - 0.032 13.8 0.1 0.077 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Seryl_tRNA_N PF02403.17 ETS79636.1 - 0.063 13.2 1.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 ETS79636.1 - 0.091 13.1 6.0 0.24 11.8 0.2 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 ETS79636.1 - 0.16 11.1 1.3 2.4 7.2 0.0 2.7 4 0 0 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 ETS79636.1 - 0.57 9.7 4.5 1.5 8.3 0.1 2.3 1 1 0 2 2 2 0 IncA protein TPP_enzyme_N PF02776.13 ETS79637.1 - 6.4e-36 123.4 0.2 1.1e-35 122.7 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS79637.1 - 1.2e-18 67.2 0.0 2.1e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 ETS79637.1 - 2e-18 66.4 0.1 6e-17 61.6 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aminotran_1_2 PF00155.16 ETS79638.1 - 2.4e-19 69.5 0.0 3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 ETS79638.1 - 3.5e-05 23.0 0.0 7.7e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 ETS79638.1 - 0.061 11.8 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase CorA PF01544.13 ETS79640.1 - 0.0023 17.0 0.1 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.17 ETS79641.1 - 1.5e-63 214.9 0.0 2.2e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MIP PF00230.15 ETS79642.1 - 1e-48 165.7 14.9 1.3e-48 165.4 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein PMT_2 PF13231.1 ETS79642.1 - 2.4 8.0 12.5 37 4.1 0.0 3.1 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase APH PF01636.18 ETS79644.1 - 9e-18 64.8 0.0 3.6e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS79644.1 - 6.4e-08 32.4 0.0 1.7e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 ETS79644.1 - 0.013 14.6 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain HET PF06985.6 ETS79645.1 - 4.4e-29 101.4 0.2 2e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.1 ETS79646.1 - 2.4e-49 168.0 44.2 2.7e-49 167.8 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS79646.1 - 7.2e-16 57.5 35.9 9.6e-16 57.1 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.3 ETS79646.1 - 4.7 6.7 5.9 6.5 6.3 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Ank_2 PF12796.2 ETS79647.1 - 3.9e-55 184.1 4.5 5.1e-14 52.3 0.1 9.2 4 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS79647.1 - 3.4e-33 110.3 15.4 0.00094 19.2 0.0 15.2 18 0 0 18 18 18 7 Ankyrin repeat Ank PF00023.25 ETS79647.1 - 5.9e-33 111.0 22.1 0.0034 17.1 0.0 15.1 16 1 1 17 17 17 9 Ankyrin repeat Ank_4 PF13637.1 ETS79647.1 - 2e-28 98.2 11.3 1.6e-05 25.2 0.0 11.6 9 3 2 12 12 12 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79647.1 - 4.1e-18 64.9 3.4 0.0064 16.7 0.1 8.7 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS79647.1 - 9.9e-08 31.7 2.0 2.6e-07 30.4 1.4 1.8 1 0 0 1 1 1 1 Clr5 domain NACHT PF05729.7 ETS79648.1 - 1.1e-08 34.9 1.0 2.8e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS79648.1 - 1.2e-05 25.4 1.6 0.00021 21.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS79648.1 - 4.8e-05 23.4 0.0 0.0014 18.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS79648.1 - 0.00024 21.2 0.0 0.02 15.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 ETS79648.1 - 0.0023 17.3 3.6 0.0085 15.5 0.1 2.7 2 1 1 3 3 3 1 AAA-like domain DUF2075 PF09848.4 ETS79648.1 - 0.0071 15.3 0.0 0.13 11.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) HALZ PF02183.13 ETS79648.1 - 0.018 14.7 0.4 0.06 13.0 0.3 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper AAA_17 PF13207.1 ETS79648.1 - 0.023 15.5 0.0 0.12 13.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS79648.1 - 0.023 13.5 0.2 0.071 11.9 0.1 2.0 2 1 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 ETS79648.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 ETS79648.1 - 0.026 13.6 0.0 0.078 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.9 ETS79648.1 - 0.026 13.5 0.4 2.5 7.0 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.1 ETS79648.1 - 0.032 14.1 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS79648.1 - 0.033 13.8 0.2 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 ETS79648.1 - 0.048 13.0 0.0 0.31 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS79648.1 - 0.048 13.9 0.0 0.24 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS79648.1 - 0.082 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 ETS79648.1 - 0.087 13.0 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETS79648.1 - 0.099 12.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 ETS79648.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 ETS79648.1 - 0.12 11.5 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.10 ETS79648.1 - 0.16 11.6 0.2 0.57 9.8 0.0 2.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 ETS79648.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain MFS_1 PF07690.11 ETS79649.1 - 5.7e-16 58.1 19.4 8.1e-16 57.6 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS79649.1 - 1.8e-05 24.2 2.3 1.8e-05 24.2 1.6 3.1 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 ETS79650.1 - 3.1e-30 104.9 2.0 8.1e-30 103.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79650.1 - 3.8e-06 26.7 9.3 3.8e-06 26.7 6.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 ETS79651.1 - 4.4e-17 62.5 0.0 5.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 ETS79652.1 - 6.2e-81 272.2 21.7 7.1e-81 272.0 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79652.1 - 6e-18 64.6 10.7 6e-18 64.6 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrpF PF04303.8 ETS79653.1 - 3.1e-107 358.5 0.1 3.6e-107 358.3 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.6 ETS79653.1 - 0.048 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Proline racemase Aconitase PF00330.15 ETS79654.1 - 2.2e-67 227.5 0.0 7.6e-67 225.7 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS79654.1 - 2.3e-44 150.6 0.0 3.5e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Ferritin PF00210.19 ETS79654.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Aconitase PF00330.15 ETS79655.1 - 3.5e-59 200.5 0.0 4.1e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Mito_carr PF00153.22 ETS79656.1 - 1e-22 79.6 6.4 1.9e-10 40.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_10 PF13460.1 ETS79657.1 - 3.7e-20 72.6 0.1 5.1e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS79657.1 - 1.5e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS79657.1 - 4.3e-08 32.6 0.0 5.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 ETS79657.1 - 4.5e-06 25.5 0.0 6.2e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS79657.1 - 0.00081 18.3 0.1 0.1 11.4 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 ETS79657.1 - 0.0027 16.7 0.0 0.032 13.2 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase p450 PF00067.17 ETS79659.1 - 1.5e-22 79.8 0.0 1.8e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 TrkH PF02386.11 ETS79660.1 - 2.1e-69 233.7 15.2 6.9e-42 143.2 3.0 3.0 3 0 0 3 3 3 3 Cation transport protein AMP-binding PF00501.23 ETS79661.1 - 1.2e-159 531.1 0.0 1.5e-84 283.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 ETS79661.1 - 8.4e-111 369.6 7.2 1.8e-50 171.5 0.1 3.3 3 0 0 3 3 3 3 Condensation domain Thioesterase PF00975.15 ETS79661.1 - 1e-30 107.6 0.0 2.3e-30 106.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 ETS79661.1 - 3.3e-29 100.9 0.0 2.5e-13 50.0 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 ETS79661.1 - 2.6e-26 91.7 1.5 3.7e-17 62.4 0.1 3.5 3 0 0 3 3 3 2 HxxPF-repeated domain AMP-binding_C PF13193.1 ETS79661.1 - 5.9e-17 62.3 0.1 9.5e-09 36.0 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HTH_22 PF13309.1 ETS79661.1 - 0.21 11.3 0.3 0.52 10.0 0.2 1.6 1 0 0 1 1 1 0 HTH domain Pkinase PF00069.20 ETS79662.1 - 1.2e-71 240.9 0.6 2.1e-71 240.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79662.1 - 1e-37 129.6 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS79662.1 - 0.00018 20.6 0.0 0.00058 18.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 ETS79662.1 - 0.0036 16.4 0.0 0.0077 15.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS79662.1 - 4.8 6.4 6.2 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Homeobox PF00046.24 ETS79663.1 - 1e-17 63.4 2.8 2.1e-17 62.4 2.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ETS79663.1 - 0.0027 17.3 0.1 0.0082 15.8 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain 3HCDH_N PF02737.13 ETS79664.1 - 1.2e-52 178.1 1.7 1.6e-52 177.7 1.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS79664.1 - 3.5e-33 113.8 0.0 7.1e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 ETS79664.1 - 6e-05 22.1 0.2 7.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 ETS79664.1 - 7.5e-05 22.6 0.4 0.00026 20.8 0.1 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 ETS79664.1 - 0.00089 18.2 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS79664.1 - 0.0072 16.0 1.0 0.015 15.0 0.7 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 ETS79664.1 - 0.02 15.2 0.1 0.055 13.8 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 ETS79664.1 - 0.024 13.8 0.3 0.062 12.4 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 ETS79664.1 - 0.032 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS79664.1 - 0.054 13.0 0.1 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 ETS79664.1 - 0.13 12.6 3.7 0.19 12.1 1.0 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 ETS79664.1 - 0.2 11.7 1.5 0.33 10.9 1.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 ETS79665.1 - 3.1e-92 308.5 0.2 3.1e-92 308.5 0.2 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 ETS79665.1 - 2.2e-35 122.6 10.8 2.2e-35 122.6 7.5 3.3 2 1 1 3 3 3 1 Timeless protein C terminal region 2-Hacid_dh_C PF02826.14 ETS79666.1 - 8.4e-50 168.3 0.0 1.3e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS79666.1 - 1.8e-15 56.5 0.0 2.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS79666.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PBP PF01161.15 ETS79667.1 - 1e-16 61.0 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox PF00070.22 ETS79668.1 - 5.3e-11 42.7 0.5 5.2e-08 33.1 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS79668.1 - 4.2e-10 39.8 0.0 8.1e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS79668.1 - 7.7e-09 35.9 1.0 0.0011 19.1 0.1 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS79668.1 - 3.6e-07 30.0 0.4 0.055 13.2 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 ETS79668.1 - 2.5e-06 26.6 4.5 0.011 14.6 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS79668.1 - 5.6e-05 22.2 0.3 0.069 12.0 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.1 ETS79668.1 - 0.00079 18.4 0.1 0.064 12.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS79668.1 - 0.031 12.9 0.8 2.6 6.5 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 ETS79668.1 - 0.054 13.4 0.4 11 6.0 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_8 PF13450.1 ETS79668.1 - 0.11 12.4 0.8 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CENP-S PF15630.1 ETS79669.1 - 1.4e-34 118.0 0.0 1.9e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 ETS79669.1 - 0.0082 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 ETS79669.1 - 0.077 12.7 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.11 ETS79669.1 - 0.083 12.7 0.1 0.1 12.3 0.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 ETS79669.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated PGA2 PF07543.7 ETS79670.1 - 3.4e-39 133.8 1.1 3.9e-39 133.6 0.7 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 Aha1_N PF09229.6 ETS79670.1 - 0.034 13.9 0.2 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal STT3 PF02516.9 ETS79670.1 - 0.052 12.5 0.0 0.059 12.3 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit ATXN-1_C PF12547.3 ETS79671.1 - 3.6 7.6 13.0 1.8 8.6 0.7 3.2 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator Malic_M PF03949.10 ETS79673.1 - 2.3e-86 289.4 0.0 4.5e-86 288.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 ETS79673.1 - 2.4e-68 229.3 0.0 3.9e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MFS_1 PF07690.11 ETS79674.1 - 1.5e-45 155.4 38.9 1.5e-45 155.4 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 ETS79674.1 - 0.72 7.8 11.1 1 7.3 0.5 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Senescence_reg PF04520.8 ETS79675.1 - 3 8.3 9.2 2.5 8.5 5.7 1.5 1 1 0 1 1 1 0 Senescence regulator Med3 PF11593.3 ETS79675.1 - 9.5 5.3 16.2 26 3.9 11.1 1.8 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal FAD_binding_4 PF01565.18 ETS79676.1 - 3.7e-27 94.5 1.4 6.1e-27 93.7 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS79676.1 - 0.00034 20.4 0.1 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Arginosuc_synth PF00764.14 ETS79677.1 - 2.1e-135 451.7 0.0 2.4e-135 451.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 ETS79677.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 ETS79677.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Fungal_trans_2 PF11951.3 ETS79678.1 - 2e-08 33.2 2.2 2.8e-08 32.7 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 ETS79679.1 - 1.9e-83 280.7 0.0 2.6e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 ETS79680.1 - 2.1e-28 99.0 30.4 2.1e-28 99.0 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 ETS79681.1 - 2.6e-32 112.0 0.0 5.6e-32 111.0 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS79681.1 - 0.045 13.7 0.8 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldo_ket_red PF00248.16 ETS79682.1 - 6.6e-50 169.5 0.0 7.3e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GAS2 PF02187.12 ETS79683.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SBDS_C PF09377.5 ETS79686.1 - 0.0094 15.6 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain FAD_binding_3 PF01494.14 ETS79687.1 - 2.4e-23 82.7 0.7 1.7e-22 80.0 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS79687.1 - 6.4e-07 28.5 2.8 0.00026 20.0 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS79687.1 - 0.00073 19.5 0.1 0.0025 17.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS79687.1 - 0.00091 18.4 0.4 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS79687.1 - 0.0034 17.7 0.3 0.063 13.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS79687.1 - 0.013 14.1 1.0 0.034 12.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 ETS79687.1 - 0.029 13.4 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HET PF06985.6 ETS79688.1 - 3.1e-36 124.5 0.2 5.2e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cobalamin_bind PF01122.14 ETS79688.1 - 0.15 10.6 0.0 0.29 9.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein BAR PF03114.13 ETS79689.1 - 2.7e-48 164.4 7.8 3.6e-48 164.0 5.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 ETS79689.1 - 5.2e-06 25.5 6.9 8.8e-06 24.8 4.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RsmJ PF04378.8 ETS79689.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ DUF3086 PF11285.3 ETS79689.1 - 0.12 11.1 1.8 0.21 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) IncA PF04156.9 ETS79689.1 - 0.37 10.3 8.7 0.59 9.6 6.0 1.2 1 0 0 1 1 1 0 IncA protein HlyD PF00529.15 ETS79689.1 - 1.2 8.4 4.6 2 7.6 3.2 1.4 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 ETS79689.1 - 3.6 6.5 10.2 1.6 7.7 5.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 5_nucleotid_C PF02872.13 ETS79690.1 - 1.1e-30 106.6 0.1 2.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 ETS79690.1 - 3.3e-10 39.7 0.4 1.9e-09 37.2 0.2 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 ETS79690.1 - 0.0034 16.4 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.5 ETS79690.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap MFS_1 PF07690.11 ETS79691.1 - 2.2e-31 108.8 24.8 2.2e-31 108.8 17.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4387 PF14330.1 ETS79692.1 - 2.6e-31 107.9 0.0 5.1e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 ETS79692.1 - 7.3e-09 34.5 0.0 9.2e-05 21.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 ETS79693.1 - 9.1e-16 57.4 0.8 1.6e-15 56.7 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N_assoc PF13823.1 ETS79694.1 - 0.00058 19.4 0.2 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_N PF08240.7 ETS79695.1 - 1.5e-17 63.2 0.9 2.9e-17 62.4 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS79695.1 - 1.4e-16 60.2 0.0 2.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS79695.1 - 0.028 15.3 0.0 0.055 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Lactamase_B PF00753.22 ETS79696.1 - 1.1e-10 41.5 0.3 1.5e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS79696.1 - 2.2e-06 27.3 0.4 3.3e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 ETS79698.1 - 6.5e-82 275.4 29.7 7.8e-82 275.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79698.1 - 6.1e-25 87.6 49.3 6.8e-19 67.7 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS79698.1 - 1.3e-05 24.9 1.2 0.0097 15.6 0.1 3.2 3 0 0 3 3 3 2 MFS_1 like family Folate_carrier PF01770.13 ETS79698.1 - 0.0048 15.4 4.4 0.0077 14.7 3.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier CFEM PF05730.6 ETS79699.1 - 5.9e-10 38.8 9.8 9.8e-10 38.1 6.8 1.3 1 0 0 1 1 1 1 CFEM domain Hid1 PF12722.2 ETS79699.1 - 0.0028 15.4 0.7 0.004 14.9 0.5 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SprA-related PF12118.3 ETS79699.1 - 0.073 12.3 20.6 0.11 11.8 14.3 1.1 1 0 0 1 1 1 0 SprA-related family Activator_LAG-3 PF11498.3 ETS79699.1 - 0.078 11.7 29.9 0.13 10.9 20.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.7 ETS79699.1 - 0.63 8.6 12.8 0.85 8.1 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.5 ETS79699.1 - 0.76 7.9 23.7 1 7.4 16.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MT0933_antitox PF14013.1 ETS79700.1 - 0.16 12.0 6.4 0.22 11.6 2.3 2.3 2 0 0 2 2 2 0 MT0933-like antitoxin protein F-box-like PF12937.2 ETS79701.1 - 2.4e-13 49.5 1.2 8e-13 47.8 0.4 2.2 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 ETS79701.1 - 1.6e-12 46.0 13.3 5.1 7.4 0.0 11.8 12 1 0 12 12 12 2 Leucine Rich repeat LRR_4 PF12799.2 ETS79701.1 - 2.2e-09 36.7 4.5 2.6 7.7 0.0 7.6 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS79701.1 - 2.7e-08 33.4 15.0 0.0012 18.5 0.0 6.2 3 1 4 7 7 7 4 Leucine rich repeat F-box PF00646.28 ETS79701.1 - 0.00058 19.4 0.4 0.0024 17.4 0.2 2.1 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.6 ETS79701.1 - 0.23 10.9 0.9 40 3.7 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1699) LRR_1 PF00560.28 ETS79701.1 - 5.9 7.3 36.6 5.3 7.4 0.2 10.7 8 4 1 9 9 9 0 Leucine Rich Repeat Chalcone PF02431.10 ETS79702.1 - 4.1e-53 179.7 0.0 5.5e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Peptidase_S10 PF00450.17 ETS79703.1 - 1.2e-95 321.1 2.2 1.5e-95 320.8 1.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase TMEM154 PF15102.1 ETS79704.1 - 0.0035 17.0 0.4 0.0085 15.8 0.3 1.7 1 1 0 1 1 1 1 TMEM154 protein family stn_TNFRSF12A PF12191.3 ETS79704.1 - 0.072 13.1 0.1 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1191 PF06697.7 ETS79704.1 - 0.079 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 ETS79704.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Nitrate_red_gam PF02665.9 ETS79704.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit AAA_10 PF12846.2 ETS79705.1 - 1.3e-07 31.3 0.1 1.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 ETS79705.1 - 0.0029 17.0 0.2 0.0099 15.3 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 ETS79705.1 - 0.0066 16.2 0.7 2.2 8.0 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function DUF87 Zeta_toxin PF06414.7 ETS79705.1 - 0.031 13.3 0.0 0.071 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 ETS79705.1 - 0.094 12.8 0.1 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain OTT_1508_deam PF14441.1 ETS79706.1 - 1.5e-09 37.7 0.4 3.1e-09 36.7 0.3 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 ETS79706.1 - 0.057 13.4 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Copine PF07002.11 ETS79706.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Copine Glutaredoxin PF00462.19 ETS79707.1 - 4.1e-18 65.1 0.0 5.8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 ETS79707.1 - 0.0028 17.2 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ETS79707.1 - 0.025 14.1 0.1 0.064 12.8 0.1 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF836 PF05768.9 ETS79707.1 - 0.049 13.8 0.1 0.065 13.4 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) BAG PF02179.11 ETS79708.1 - 4.1e-18 65.2 0.3 4.1e-18 65.2 0.2 1.7 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 ETS79708.1 - 5.4e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 ETS79708.1 - 0.042 14.0 0.1 0.087 13.0 0.1 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF566 PF04484.7 ETS79708.1 - 1.5 8.2 6.6 0.7 9.3 3.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF566) Ribosomal_L13 PF00572.13 ETS79709.1 - 1.9e-28 99.0 0.0 3.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 ETS79709.1 - 0.06 12.8 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MFS_1 PF07690.11 ETS79710.1 - 4.1e-32 111.2 66.0 2.4e-31 108.7 38.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 ETS79711.1 - 7.8e-39 133.3 4.7 1.3e-38 132.6 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 ETS79712.1 - 6.8e-21 74.0 0.1 1.8e-13 49.5 0.1 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS79712.1 - 0.00069 18.4 2.0 0.0012 17.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 ETS79712.1 - 0.0045 15.6 0.0 0.0074 14.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase Lactonase PF10282.4 ETS79714.1 - 3.7e-90 302.4 0.6 4.5e-90 302.2 0.4 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FAD_binding_4 PF01565.18 ETS79715.1 - 2.7e-27 94.9 5.8 1.2e-25 89.6 3.7 2.9 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 ETS79715.1 - 3.5e-13 49.2 0.2 7.5e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like AA_permease PF00324.16 ETS79716.1 - 1.6e-115 386.1 42.5 2e-115 385.9 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS79716.1 - 4e-22 78.3 44.7 5.3e-22 77.9 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 ETS79716.1 - 0.18 11.2 0.0 0.18 11.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) PLDc_2 PF13091.1 ETS79717.1 - 1.4e-17 63.5 0.0 1e-11 44.6 0.0 2.9 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETS79717.1 - 0.0049 16.6 0.0 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 ETS79717.1 - 0.017 14.1 0.3 0.71 8.7 0.0 2.5 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB DUF3102 PF11300.3 ETS79717.1 - 0.1 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Fungal_trans PF04082.13 ETS79718.1 - 0.0004 19.3 0.0 0.00079 18.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPOR PF05036.8 ETS79718.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain DUF2293 PF10056.4 ETS79719.1 - 1.3e-26 92.3 0.4 3.2e-26 91.0 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) CsbD PF05532.7 ETS79720.1 - 3.9e-20 71.2 19.3 3.7e-10 39.3 4.1 3.2 2 1 1 3 3 3 3 CsbD-like DUF2937 PF11157.3 ETS79720.1 - 0.2 10.9 0.9 0.35 10.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Gly-zipper_Omp PF13488.1 ETS79721.1 - 0.067 12.8 3.2 0.18 11.4 2.2 1.7 1 0 0 1 1 1 0 Glycine zipper Glug PF07581.7 ETS79721.1 - 0.08 13.1 1.3 0.41 10.9 0.9 2.3 1 0 0 1 1 1 0 The GLUG motif LIP PF03583.9 ETS79721.1 - 0.24 10.5 3.3 0.79 8.8 0.1 2.3 2 0 0 2 2 2 0 Secretory lipase YoqO PF14037.1 ETS79722.1 - 0.041 13.9 0.9 0.041 13.9 0.6 3.3 3 0 0 3 3 3 0 YoqO-like protein Amidase PF01425.16 ETS79723.1 - 2.5e-97 326.5 0.0 2.9e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Connexin50 PF03509.9 ETS79723.1 - 0.089 13.1 0.1 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 Gap junction alpha-8 protein (Cx50) MFS_1 PF07690.11 ETS79724.1 - 3.1e-32 111.6 48.6 8.2e-30 103.7 19.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily EVC2_like PF12297.3 ETS79724.1 - 0.049 12.2 0.1 7.3 5.0 0.0 2.5 3 0 0 3 3 3 0 Ellis van Creveld protein 2 like protein Amnionless PF14828.1 ETS79724.1 - 0.2 10.0 0.0 0.48 8.8 0.0 1.5 2 0 0 2 2 2 0 Amnionless Fungal_trans PF04082.13 ETS79725.1 - 5.6e-29 100.7 1.9 9.7e-29 100.0 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS79725.1 - 1.2e-08 34.6 8.5 1.2e-08 34.6 5.9 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCSMST1 PF15013.1 ETS79725.1 - 0.12 12.2 0.1 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 CCSMST1 family CRCB PF02537.10 ETS79726.1 - 4.2e-31 107.2 17.5 1.8e-20 72.9 4.8 3.5 3 1 0 3 3 3 3 CrcB-like protein DctQ PF04290.7 ETS79726.1 - 4.9 6.9 12.1 0.043 13.5 2.2 2.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component adh_short_C2 PF13561.1 ETS79727.1 - 1.4e-36 126.4 0.1 1.7e-36 126.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS79727.1 - 4.3e-22 78.7 0.4 5.8e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79727.1 - 1.7e-09 37.6 0.1 2.4e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1537 PF07005.6 ETS79727.1 - 0.038 13.6 0.5 0.71 9.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF1537 ILVD_EDD PF00920.16 ETS79728.1 - 6.1e-156 519.8 0.7 7e-156 519.6 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family MFS_1 PF07690.11 ETS79729.1 - 3.7e-21 75.2 36.8 2e-20 72.8 24.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.7 ETS79729.1 - 0.43 10.1 1.8 2.6 7.6 0.7 2.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SGL PF08450.7 ETS79730.1 - 2.2e-34 118.9 0.0 2.5e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 ETS79730.1 - 5.1e-06 26.4 0.0 0.61 10.1 0.0 3.6 1 1 2 3 3 3 2 Strictosidine synthase NHL PF01436.16 ETS79730.1 - 6e-05 22.7 0.0 8.6 6.5 0.0 5.7 6 0 0 6 6 6 1 NHL repeat SBBP PF06739.6 ETS79730.1 - 0.0077 15.9 0.6 0.041 13.6 0.2 2.4 3 0 0 3 3 3 1 Beta-propeller repeat Arylesterase PF01731.15 ETS79730.1 - 0.1 12.6 0.0 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Arylesterase MFS_1 PF07690.11 ETS79731.1 - 1.1e-43 149.3 45.3 1.8e-43 148.5 27.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA_bind PF01588.15 ETS79732.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative tRNA binding domain Abhydrolase_6 PF12697.2 ETS79733.1 - 8.9e-32 110.7 0.3 1.2e-31 110.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS79733.1 - 2.3e-13 50.1 0.0 5.7e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS79733.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 ETS79733.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3089 PF11288.3 ETS79733.1 - 0.024 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 ETS79733.1 - 0.047 13.2 0.0 0.092 12.3 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Pyridox_oxidase PF01243.15 ETS79734.1 - 9.8e-19 67.1 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 ETS79734.1 - 2.2e-14 52.6 1.0 3.7e-14 51.9 0.7 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 ETS79734.1 - 1.7e-07 31.4 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UnbV_ASPIC PF07593.7 ETS79735.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV CRAL_TRIO PF00650.15 ETS79736.1 - 1.7e-24 86.1 0.0 2.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS79736.1 - 1.1e-08 35.0 0.0 3.5e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SnoaL PF07366.7 ETS79737.1 - 1.7e-13 50.2 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 ETS79737.1 - 8.7e-06 26.0 0.0 1.1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 ETS79738.1 - 2.6e-05 23.8 0.1 8e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 ETS79738.1 - 0.0013 19.1 0.0 0.0021 18.4 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain Pterin_4a PF01329.14 ETS79738.1 - 0.091 12.5 4.8 3.1 7.5 0.2 2.8 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase p450 PF00067.17 ETS79739.1 - 5.4e-64 216.4 0.0 6.6e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCD14 PF08704.5 ETS79740.1 - 1e-60 205.3 0.1 8.2e-59 199.0 0.0 3.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 ETS79740.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79740.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3759 PF12585.3 ETS79741.1 - 2.3e-38 129.9 6.4 2.8e-38 129.6 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PAF-AH_p_II PF03403.8 ETS79742.1 - 4.5e-42 143.6 0.0 2.8e-37 127.8 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 ETS79742.1 - 5e-10 39.3 0.1 1.7e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS79742.1 - 0.00081 19.3 0.2 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS79742.1 - 0.0024 16.7 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS79742.1 - 0.017 13.9 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.13 ETS79742.1 - 0.031 13.5 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_M18 PF02127.10 ETS79743.1 - 5.5e-124 413.9 0.0 6.3e-124 413.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_hydro_76 PF03663.9 ETS79744.1 - 1.8e-128 429.0 11.3 2.2e-128 428.7 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Transferase PF02458.10 ETS79745.1 - 5.3e-21 74.5 0.0 4e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family Aldo_ket_red PF00248.16 ETS79746.1 - 1.6e-64 217.4 0.0 1.8e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1546 PF07571.8 ETS79747.1 - 2.1e-25 88.6 0.0 4.8e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 ETS79747.1 - 1.6e-22 79.2 0.0 2.9e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 ETS79747.1 - 0.01 15.9 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS79747.1 - 0.013 15.5 0.1 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sdh_cyt PF01127.17 ETS79748.1 - 1.7e-16 60.1 3.0 2.4e-16 59.6 2.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.11 ETS79749.1 - 9.1e-33 113.4 27.2 9.1e-33 113.4 18.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.6 ETS79750.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Zn_clus PF00172.13 ETS79751.1 - 0.0015 18.3 8.5 0.0028 17.5 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 ETS79752.1 - 6.8e-111 370.5 0.0 8.3e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS79752.1 - 1.1e-18 66.7 0.0 2.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 ETS79752.1 - 7.6e-05 22.0 0.0 0.00017 20.8 0.0 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 ETS79752.1 - 9.3e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS79752.1 - 0.00026 19.9 0.5 0.0009 18.2 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ETS79752.1 - 0.029 13.4 0.0 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG F-box PF00646.28 ETS79753.1 - 2.6e-09 36.4 1.1 6e-09 35.3 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS79753.1 - 5.8e-05 22.7 4.5 0.00013 21.5 3.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3945 PF13101.1 ETS79753.1 - 0.03 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Ubie_methyltran PF01209.13 ETS79754.1 - 2e-07 30.3 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ETS79754.1 - 6.2e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS79754.1 - 3e-06 27.5 0.0 5.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79754.1 - 1.6e-05 25.2 0.0 2.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79754.1 - 0.00011 21.7 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TFIIE-A_C-term PF11521.3 ETS79754.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Tannase PF07519.6 ETS79755.1 - 9.2e-98 327.9 1.7 1.9e-96 323.6 1.2 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 ETS79755.1 - 0.023 14.4 0.1 0.14 11.9 0.1 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS79755.1 - 0.044 13.6 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cofilin_ADF PF00241.15 ETS79756.1 - 1.1e-14 54.4 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Adaptin_binding PF10199.4 ETS79757.1 - 5.8e-17 62.2 1.2 1.3e-16 61.1 0.8 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Homeobox PF00046.24 ETS79758.1 - 2.8e-19 68.4 4.6 5.6e-19 67.5 3.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ETS79758.1 - 0.00018 21.1 0.7 0.00062 19.4 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 ETS79759.1 - 3.1e-21 75.4 0.1 1.3e-20 73.4 0.1 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 ETS79759.1 - 1.5e-17 64.7 0.2 1e-12 48.9 0.1 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS79759.1 - 2e-14 54.2 0.1 1.3e-13 51.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS79759.1 - 4.9e-10 39.2 0.0 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS79759.1 - 0.0024 17.4 0.1 0.0067 16.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS79759.1 - 0.035 14.3 0.1 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HlyIII PF03006.15 ETS79760.1 - 1.3e-12 47.6 0.6 1.5e-12 47.4 0.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related MFS_1 PF07690.11 ETS79761.1 - 1.1e-17 63.8 23.2 1.5e-17 63.3 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.18 ETS79762.1 - 2.9e-61 207.3 0.9 3.6e-61 207.0 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS79762.1 - 0.0001 21.7 1.7 0.033 13.5 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 ETS79763.1 - 8.1e-41 139.8 38.7 8.1e-41 139.8 26.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79763.1 - 2.4e-08 33.0 28.7 1e-05 24.3 3.0 3.2 2 1 0 3 3 3 3 Sugar (and other) transporter Ca_hom_mod PF14798.1 ETS79763.1 - 0.24 10.3 1.1 1.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Calcium homeostasis modulator DUF4094 PF13334.1 ETS79763.1 - 0.55 10.6 9.8 1 9.7 0.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) MFS_1 PF07690.11 ETS79764.1 - 1.3e-35 122.7 38.4 1.3e-35 122.7 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79764.1 - 3.4e-15 55.5 10.7 3.4e-15 55.5 7.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.19 ETS79765.1 - 4.3e-53 180.5 33.5 5e-53 180.2 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79765.1 - 1.2e-11 43.9 39.5 1.2e-11 43.9 27.4 2.8 1 1 2 3 3 3 1 Major Facilitator Superfamily zf-RNPHF PF08080.7 ETS79765.1 - 0.032 13.7 0.1 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 RNPHF zinc finger ATP1G1_PLM_MAT8 PF02038.11 ETS79765.1 - 1.8 7.6 7.9 8.1 5.5 1.0 3.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Bac_rhamnosid PF05592.6 ETS79766.1 - 2.4e-34 118.4 0.2 3.3e-34 117.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 ETS79766.1 - 1.8e-09 37.3 0.0 6.3e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 ETS79766.1 - 0.0096 14.6 0.8 0.014 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF608 NMT1 PF09084.6 ETS79767.1 - 2.5e-05 24.0 0.0 0.00049 19.7 0.0 2.0 1 1 0 2 2 2 1 NMT1/THI5 like YihI PF04220.7 ETS79767.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) FLILHELTA PF10306.4 ETS79768.1 - 7.3e-19 67.6 0.0 1.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 ETS79768.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.14 ETS79769.1 - 6e-54 181.4 0.0 9.8e-54 180.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 ETS79770.1 - 1.1e-154 515.5 3.3 1.4e-154 515.2 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS79770.1 - 6.3e-22 77.2 0.1 1.7e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like 4HBT_3 PF13622.1 ETS79771.1 - 5.7e-31 108.1 0.3 7.1e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DER1 PF04511.10 ETS79772.1 - 1.1e-18 67.4 4.5 1.3e-18 67.1 3.1 1.0 1 0 0 1 1 1 1 Der1-like family CN_hydrolase PF00795.17 ETS79774.1 - 1.5e-11 43.9 0.0 2.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DKCLD PF08068.7 ETS79776.1 - 4.1e-27 93.8 0.0 1.5e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 ETS79776.1 - 1.6e-23 83.5 3.9 1.5e-21 77.0 0.2 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 ETS79776.1 - 3.2e-20 71.6 1.0 6.1e-20 70.7 0.7 1.5 1 0 0 1 1 1 1 PUA domain Med3 PF11593.3 ETS79776.1 - 0.068 12.3 2.7 0.082 12.1 1.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med19 PF10278.4 ETS79776.1 - 1.2 8.7 9.6 2.1 7.9 6.7 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 ETS79776.1 - 1.3 8.8 8.4 1.9 8.3 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IER PF05760.7 ETS79776.1 - 2 8.2 8.6 2.7 7.8 6.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Glyco_hydro_43 PF04616.9 ETS79777.1 - 4.5e-30 104.7 0.0 8.9e-30 103.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 SKG6 PF08693.5 ETS79778.1 - 0.00048 19.3 0.2 0.001 18.3 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 ETS79778.1 - 0.027 14.0 0.4 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 Podoplanin ArgJ PF01960.13 ETS79779.1 - 2.9e-149 496.7 0.3 3.2e-149 496.5 0.2 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.6 ETS79780.1 - 2.2e-19 69.2 0.0 4.4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 ETS79780.1 - 1.1e-11 44.6 0.0 8.8e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 ETS79780.1 - 2.5e-11 43.8 0.0 4.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS79780.1 - 2.2e-07 30.8 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS79780.1 - 2.2e-06 27.7 0.0 8.9e-05 22.5 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS79780.1 - 1.8e-05 24.8 0.1 0.0048 17.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS79780.1 - 2.3e-05 23.5 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 ETS79780.1 - 2.5e-05 23.1 0.0 0.017 13.8 0.0 2.6 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 ETS79780.1 - 0.00017 21.2 0.0 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 ETS79780.1 - 0.00017 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 ETS79780.1 - 0.00021 20.8 0.1 0.042 13.2 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 ETS79780.1 - 0.0016 17.8 0.0 0.07 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS79780.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 ETS79780.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 ETS79780.1 - 0.0028 16.8 0.0 0.026 13.6 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 ETS79780.1 - 0.0034 16.8 0.1 0.16 11.4 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 ETS79780.1 - 0.0066 16.1 0.4 0.031 13.9 0.1 2.2 2 1 1 3 3 2 1 NTPase ArgK PF03308.11 ETS79780.1 - 0.0067 15.2 0.1 0.018 13.8 0.0 1.6 1 1 1 2 2 2 1 ArgK protein AAA_5 PF07728.9 ETS79780.1 - 0.0088 15.7 0.0 0.043 13.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) KTI12 PF08433.5 ETS79780.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 ETS79780.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS79780.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS79780.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 ETS79780.1 - 0.019 14.8 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.3 ETS79780.1 - 0.09 12.5 0.2 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III NB-ARC PF00931.17 ETS79780.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mito_carr PF00153.22 ETS79782.1 - 4e-19 68.1 0.0 4.8e-11 42.2 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein GFA PF04828.9 ETS79783.1 - 2.1e-09 37.1 0.7 4.1e-09 36.2 0.5 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ORC2 PF04084.9 ETS79784.1 - 1.9e-97 325.9 0.0 2.5e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PPP4R2 PF09184.6 ETS79784.1 - 0.95 8.9 9.6 1.6 8.2 6.7 1.3 1 0 0 1 1 1 0 PPP4R2 PGP_phosphatase PF09419.5 ETS79785.1 - 1.1e-62 210.2 0.0 1.3e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 ETS79785.1 - 3.5e-06 26.6 0.0 6.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like CutC PF03932.9 ETS79787.1 - 6.2e-35 120.2 0.0 1.9e-33 115.4 0.0 2.0 1 1 0 1 1 1 1 CutC family FMN_dh PF01070.13 ETS79787.1 - 0.13 11.0 0.1 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glyco_hydro_18 PF00704.23 ETS79788.1 - 4.4e-41 141.4 3.6 8.3e-40 137.2 2.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS79788.1 - 0.00042 20.2 21.0 0.0025 17.7 14.8 2.1 1 1 1 2 2 2 1 Chitin recognition protein SAM_decarbox PF01536.11 ETS79789.1 - 1.7e-86 289.8 0.0 1.1e-54 185.3 0.0 3.0 2 1 1 3 3 3 3 Adenosylmethionine decarboxylase ParA PF10609.4 ETS79790.1 - 2.6e-36 123.3 0.1 4.3e-36 122.6 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS79790.1 - 5.3e-15 55.3 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 ETS79790.1 - 2e-07 30.3 0.0 4.2e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 ETS79790.1 - 1.6e-05 24.1 0.2 3.8e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 ETS79790.1 - 2.4e-05 24.3 0.1 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 ETS79790.1 - 0.00091 18.0 0.3 0.0017 17.2 0.2 1.3 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 ETS79790.1 - 0.0023 17.3 0.1 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 ETS79790.1 - 0.0058 16.0 0.2 0.0088 15.4 0.2 1.4 1 1 0 1 1 1 1 YhjQ protein DUF258 PF03193.11 ETS79790.1 - 0.033 13.3 0.2 0.067 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 ETS79790.1 - 0.096 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.1 ETS79790.1 - 0.16 11.5 0.7 16 5.0 0.4 2.2 2 0 0 2 2 2 0 AAA domain DUF898 PF05987.8 ETS79792.1 - 0.14 11.0 4.6 1.6 7.5 2.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) SUR7 PF06687.7 ETS79792.1 - 0.56 9.7 3.2 6.3 6.2 2.2 2.0 1 1 1 2 2 2 0 SUR7/PalI family DUF4231 PF14015.1 ETS79792.1 - 1.2 9.1 4.7 16 5.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HMGL-like PF00682.14 ETS79794.1 - 6.9e-69 232.1 0.8 1e-68 231.5 0.6 1.2 1 0 0 1 1 1 1 HMGL-like Flavin_Reduct PF01613.13 ETS79795.1 - 5.3e-21 75.0 0.0 8.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_16 PF00722.16 ETS79796.1 - 4.8e-10 39.0 0.7 9.8e-10 38.0 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Lactamase_B_2 PF12706.2 ETS79797.1 - 2.2e-32 112.2 1.2 4.4e-32 111.1 0.8 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 ETS79797.1 - 3.5e-26 90.4 0.1 8.3e-26 89.2 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 ETS79797.1 - 3.2e-07 30.2 1.0 1.5e-06 27.9 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3221 PF11518.3 ETS79797.1 - 0.12 12.0 0.0 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) COesterase PF00135.23 ETS79798.1 - 3e-60 204.4 0.0 3.6e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS79798.1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79798.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family T2SK PF03934.8 ETS79798.1 - 0.11 11.5 0.3 3 6.9 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Glyco_hydro_11 PF00457.12 ETS79799.1 - 1.2e-78 262.6 25.3 1.5e-78 262.3 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 BA14K PF07886.6 ETS79799.1 - 1.3 8.7 5.5 4.6 7.0 0.6 2.6 2 0 0 2 2 2 0 BA14K-like protein Cation_ATPase_C PF00689.16 ETS79800.1 - 0.00073 19.1 5.8 0.00073 19.1 4.0 2.1 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus GST_N_3 PF13417.1 ETS79801.1 - 0.0077 16.4 0.1 0.061 13.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS79801.1 - 0.014 15.3 0.1 0.05 13.6 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain VCBS PF13517.1 ETS79802.1 - 2.6e-29 101.3 58.5 1.5e-10 41.2 1.7 8.9 6 2 4 10 10 10 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS79802.1 - 1.7e-14 52.9 36.4 0.011 15.3 0.1 8.2 7 0 0 7 7 7 7 FG-GAP repeat Lipase_GDSL PF00657.17 ETS79802.1 - 1.1e-12 48.3 0.5 2.6e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS79802.1 - 3.2e-12 46.9 0.3 9.1e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 ETS79802.1 - 6.4e-09 35.4 15.3 0.26 10.7 0.0 6.3 4 2 3 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 ETS79802.1 - 0.44 10.2 1.5 3.3 7.4 1.0 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.20 ETS79804.1 - 0.0051 16.7 0.9 0.023 14.5 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS79804.1 - 0.022 14.5 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Terpene_synth_C PF03936.11 ETS79805.1 - 6.9e-06 25.4 0.3 1.3e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3106 PF11304.3 ETS79805.1 - 0.47 10.9 4.5 0.16 12.3 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Col_cuticle_N PF01484.12 ETS79806.1 - 0.034 13.8 0.0 0.15 11.7 0.0 2.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain HET PF06985.6 ETS79807.1 - 7.5e-34 116.8 0.4 1.2e-33 116.1 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS79808.1 - 4.9e-44 150.6 0.0 6.1e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stb3 PF10330.4 ETS79809.1 - 3.3e-36 122.8 0.0 5.3e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 ETS79810.1 - 2.6e-90 303.1 0.0 3.2e-85 286.4 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 ETS79810.1 - 2.3e-19 69.2 0.0 5.6e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.7 ETS79811.1 - 8e-40 136.5 10.1 1e-39 136.2 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 ETS79811.1 - 0.11 12.7 0.7 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Crystall PF00030.14 ETS79811.1 - 0.13 12.1 0.5 3.5 7.5 0.2 2.5 2 0 0 2 2 2 0 Beta/Gamma crystallin DUF4149 PF13664.1 ETS79813.1 - 1.4e-21 76.4 3.0 2.7e-21 75.5 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 ETS79814.1 - 3.7e-24 85.2 0.0 8.2e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 ETS79814.1 - 6.6e-19 68.2 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 ETS79814.1 - 2.2e-14 53.4 0.0 4.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like DUF3502 PF12010.3 ETS79814.1 - 0.094 12.6 1.0 3.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) DnaJ PF00226.26 ETS79817.1 - 1.5e-07 30.9 0.1 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 ETS79817.1 - 5.3e-06 26.2 0.1 6.4e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 ETS79817.1 - 0.036 13.3 1.1 0.036 13.3 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) TMP_2 PF06791.8 ETS79817.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Ribosomal_L24e PF01246.15 ETS79818.1 - 7.8e-29 99.3 2.4 7.8e-29 99.3 1.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Death PF00531.17 ETS79818.1 - 0.031 14.0 0.2 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Death domain DUF3602 PF12223.3 ETS79819.1 - 1.7e-13 50.7 15.3 6.6e-05 23.2 1.0 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) K_channel_TID PF07941.6 ETS79819.1 - 3.3 8.0 16.8 0.079 13.1 1.6 3.4 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Gly_rich PF12810.2 ETS79819.1 - 7.3 6.1 13.9 11 5.4 8.8 1.9 1 1 0 1 1 1 0 Glycine rich protein zf-C2H2 PF00096.21 ETS79820.1 - 0.037 14.3 5.6 0.096 13.0 3.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS79820.1 - 0.041 14.2 2.1 1.6 9.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 ETS79820.1 - 0.061 13.0 3.5 0.14 11.9 2.5 1.6 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 ETS79820.1 - 0.13 12.6 7.6 0.1 12.9 3.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1446 PF07287.6 ETS79822.1 - 2.1e-123 411.3 0.0 2.6e-123 411.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Lactamase_B PF00753.22 ETS79823.1 - 2.8e-06 27.1 6.5 2.2e-05 24.2 4.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS79823.1 - 0.00011 21.8 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EthD PF07110.6 ETS79824.1 - 6.7e-19 68.6 0.3 9e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 EthD domain Oxidored_FMN PF00724.15 ETS79825.1 - 3.6e-74 249.8 0.0 5.3e-53 180.2 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 ETS79826.1 - 6.6e-21 74.3 0.0 1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpi1 PF05024.10 ETS79826.1 - 0.0092 15.6 0.8 0.016 14.8 0.6 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Tannase PF07519.6 ETS79827.1 - 3.8e-102 342.4 0.9 3.5e-101 339.2 0.6 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Glyco_transf_28 PF03033.15 ETS79828.1 - 1.7e-23 82.9 0.0 5.2e-23 81.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS79828.1 - 1.8e-06 26.8 0.0 2.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS79828.1 - 0.23 11.0 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Fungal_trans_2 PF11951.3 ETS79829.1 - 0.00015 20.5 0.7 0.00024 19.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.6 ETS79830.1 - 2.1e-82 277.3 1.9 2.7e-82 276.9 1.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS79830.1 - 5.8e-07 29.6 0.0 3.5e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS79830.1 - 4e-05 22.9 0.0 0.006 15.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS79830.1 - 4.4e-05 23.1 0.6 6.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS79830.1 - 0.0065 16.2 0.5 0.21 11.3 0.1 2.6 1 1 2 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS79830.1 - 0.017 14.5 0.1 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase RTA1 PF04479.8 ETS79831.1 - 5.7e-41 140.4 5.7 6.6e-41 140.2 4.0 1.0 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 ETS79832.1 - 6e-47 160.0 4.6 1.1e-46 159.1 3.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Scs3p PF10261.4 ETS79832.1 - 0.78 8.7 4.4 0.63 9.0 0.1 2.3 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM HemY_N PF07219.8 ETS79832.1 - 3.7 7.1 4.9 3.8 7.1 0.2 2.9 3 0 0 3 3 3 0 HemY protein N-terminus Bac_rhamnosid PF05592.6 ETS79833.1 - 2.9e-27 95.0 0.3 3.8e-24 84.8 0.8 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS79833.1 - 0.00019 20.2 0.0 0.00037 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 ETS79833.1 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_1 PF00232.13 ETS79834.1 - 1.3e-133 445.5 0.0 1.6e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 ETS79834.1 - 0.027 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core E2 PF08199.6 ETS79834.1 - 1 9.0 4.8 6.7 6.3 0.1 3.0 2 1 1 3 3 3 0 Bacteriophage E2-like protein Zn_clus PF00172.13 ETS79835.1 - 8.7e-07 28.7 14.8 9.9e-07 28.5 8.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS79835.1 - 0.008 15.0 1.4 0.014 14.2 0.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS79836.1 - 7.5e-83 278.5 30.5 8.7e-83 278.3 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79836.1 - 8.3e-40 136.5 54.5 1.1e-33 116.4 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS79836.1 - 3.1e-07 29.1 19.6 7.7e-07 27.8 6.4 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 ETS79836.1 - 0.00073 19.2 0.9 0.14 12.0 0.2 3.0 2 0 0 2 2 2 2 MFS_1 like family LacY_symp PF01306.14 ETS79836.1 - 0.0015 17.2 16.0 0.047 12.2 0.0 2.5 2 0 0 2 2 2 2 LacY proton/sugar symporter Glyco_hydro_2_C PF02836.12 ETS79837.1 - 1.9e-101 338.8 0.1 2.6e-101 338.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 ETS79837.1 - 6.2e-60 202.5 0.0 9.3e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 ETS79837.1 - 8.9e-49 165.2 0.0 1.8e-48 164.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS79837.1 - 7.9e-08 32.7 0.0 2.7e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 PHD PF00628.24 ETS79840.1 - 2.6e-06 27.0 8.8 1.8e-05 24.3 1.4 2.4 2 0 0 2 2 2 2 PHD-finger ING PF12998.2 ETS79840.1 - 1.2e-05 25.5 0.0 3.5e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-PARP PF00645.13 ETS79840.1 - 0.12 12.6 3.1 0.26 11.5 2.1 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-LITAF-like PF10601.4 ETS79841.1 - 4.3e-15 55.3 6.0 6.5e-15 54.7 4.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.1 ETS79841.1 - 0.0032 16.9 1.0 1.7 8.2 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Sgf11 PF08209.6 ETS79841.1 - 0.0042 16.3 1.5 0.94 8.8 0.1 2.5 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) OATP PF03137.15 ETS79841.1 - 0.043 11.8 0.2 0.059 11.4 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family zf-ribbon_3 PF13248.1 ETS79841.1 - 0.064 12.4 4.3 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Pex14_N PF04695.8 ETS79841.1 - 4.4 7.3 21.4 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.16 ETS79842.1 - 3.7e-67 226.1 0.0 4.6e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.2 ETS79844.1 - 3.3e-18 66.4 0.0 5.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS79844.1 - 5.7e-12 45.6 0.0 1.9e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BMC PF00936.14 ETS79844.1 - 0.018 14.7 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 BMC domain Ser_hydrolase PF06821.8 ETS79844.1 - 0.018 14.6 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.8 ETS79844.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 ETS79844.1 - 0.022 13.6 0.0 0.061 12.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 ETS79844.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 ETS79844.1 - 0.074 12.5 0.2 0.14 11.6 0.2 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 ETS79844.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) AIP3 PF03915.8 ETS79845.1 - 6.9 5.4 8.1 8.9 5.0 5.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 ABC_membrane PF00664.18 ETS79846.1 - 8.9e-77 258.1 29.2 1e-39 136.6 5.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS79846.1 - 1.4e-62 209.9 0.0 2.4e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS79846.1 - 1e-14 54.3 2.9 0.00017 20.8 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS79846.1 - 3.7e-09 36.9 0.3 0.0025 17.8 0.0 4.6 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 ETS79846.1 - 2.8e-08 34.6 0.0 0.0091 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS79846.1 - 3e-07 30.6 1.1 0.047 13.8 0.0 4.1 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS79846.1 - 2e-06 27.8 9.5 0.0019 18.1 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS79846.1 - 3e-06 26.6 0.0 0.038 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 ETS79846.1 - 1.2e-05 24.9 0.8 0.03 13.9 0.0 4.3 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 ETS79846.1 - 2.7e-05 23.6 0.1 4.6 6.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 ETS79846.1 - 0.00017 21.8 0.0 0.37 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS79846.1 - 0.00037 20.3 1.5 0.2 11.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS79846.1 - 0.0005 19.3 0.0 0.094 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS79846.1 - 0.00088 18.8 0.5 0.37 10.1 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 ETS79846.1 - 0.00093 18.9 0.1 0.87 9.3 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 ETS79846.1 - 0.0012 19.0 0.3 8 6.6 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 ETS79846.1 - 0.002 17.9 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 ABC_ATPase PF09818.4 ETS79846.1 - 0.0035 15.9 0.4 0.025 13.1 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 ETS79846.1 - 0.0071 16.2 0.8 2.2 8.2 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 ETS79846.1 - 0.013 15.4 0.0 4.6 7.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 ETS79846.1 - 0.026 14.1 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 ETS79846.1 - 0.029 14.0 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 ETS79846.1 - 0.034 14.4 0.8 4.4 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 ETS79846.1 - 0.12 11.0 0.0 0.75 8.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ABC2_membrane PF01061.19 ETS79847.1 - 2.6e-86 288.1 64.3 1.3e-46 158.4 17.1 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 ETS79847.1 - 7.9e-35 120.1 0.1 1.7e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS79847.1 - 2.9e-34 116.8 1.6 6.4e-27 93.2 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 ETS79847.1 - 1.6e-13 50.5 0.0 3.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 ETS79847.1 - 9.2e-11 41.3 43.2 8.1e-07 28.3 15.0 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 ETS79847.1 - 1.3e-08 34.4 0.1 5.2e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS79847.1 - 1e-06 28.8 3.5 1.1e-05 25.4 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain DUF258 PF03193.11 ETS79847.1 - 0.00011 21.3 0.2 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS79847.1 - 0.00016 21.0 1.8 0.035 13.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 ETS79847.1 - 0.0011 18.8 0.6 0.088 12.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS79847.1 - 0.012 15.7 1.2 0.69 10.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 ETS79847.1 - 0.013 15.5 0.0 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 ETS79847.1 - 0.014 14.8 3.2 0.05 13.0 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 ETS79847.1 - 0.014 16.1 0.0 0.28 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS79847.1 - 0.015 15.0 0.4 6.9 6.5 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 ETS79847.1 - 0.019 15.2 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETS79847.1 - 0.025 13.8 0.0 3.9 6.6 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 ETS79847.1 - 0.032 14.5 0.1 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 ETS79847.1 - 0.083 12.5 2.9 2.8 7.5 0.4 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 ETS79847.1 - 0.11 12.4 0.2 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS79847.1 - 0.25 10.7 1.8 6.3 6.1 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain Peptidase_S28 PF05577.7 ETS79848.1 - 2.6e-47 161.4 1.9 4.3e-46 157.3 1.3 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 MFS_1 PF07690.11 ETS79849.1 - 1.9e-40 138.6 49.2 2.2e-40 138.4 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79849.1 - 2.2e-10 39.7 21.2 1.2e-09 37.2 12.0 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MUG113 PF13455.1 ETS79850.1 - 8e-31 106.3 0.1 1.8e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 ETS79850.1 - 3.1e-23 82.0 0.1 7.6e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain SLD3 PF08639.5 ETS79850.1 - 0.2 10.2 3.2 0.88 8.1 0.0 2.2 2 0 0 2 2 2 0 DNA replication regulator SLD3 RAI16-like PF10257.4 ETS79852.1 - 5.9e-76 255.6 4.1 9.5e-76 255.0 2.9 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Lipase_3 PF01764.20 ETS79853.1 - 1.7e-19 69.8 0.0 4.6e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 ETS79853.1 - 0.04 13.2 0.1 0.34 10.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 ETS79853.1 - 0.045 13.3 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Hydrophobin PF01185.13 ETS79855.1 - 2e-11 44.1 5.6 2.6e-11 43.7 3.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin SNF2_N PF00176.18 ETS79857.1 - 8.9e-71 238.1 1.6 1.9e-70 237.0 1.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 ETS79857.1 - 6.6e-51 172.0 18.2 6.6e-51 172.0 12.6 5.8 4 2 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 ETS79857.1 - 1.6e-16 59.9 0.0 6.1e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 ETS79858.1 - 1.5e-45 154.8 0.0 3.3e-21 76.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 ETS79858.1 - 2.6e-19 70.2 0.8 0.00022 21.2 0.0 4.8 4 1 1 5 5 5 4 AAA domain ABC_tran_2 PF12848.2 ETS79858.1 - 4.5e-18 64.8 8.1 4.5e-18 64.8 5.6 2.7 4 0 0 4 4 1 1 ABC transporter SMC_N PF02463.14 ETS79858.1 - 6.5e-10 38.6 0.1 0.014 14.6 0.0 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS79858.1 - 7.4e-09 35.0 0.0 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS79858.1 - 4.4e-08 33.6 8.1 0.023 15.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS79858.1 - 1.3e-07 32.4 0.9 0.0043 17.8 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 ETS79858.1 - 2.5e-07 31.0 0.4 0.066 13.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 ETS79858.1 - 7.9e-07 28.3 0.0 0.0023 17.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS79858.1 - 1.8e-06 28.1 0.0 0.071 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 ETS79858.1 - 4.5e-06 26.4 0.1 0.11 12.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 ETS79858.1 - 2.1e-05 24.5 0.0 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS79858.1 - 2.1e-05 24.7 0.0 0.4 10.8 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 ETS79858.1 - 2.9e-05 24.5 0.0 0.054 13.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS79858.1 - 4.1e-05 23.5 0.8 0.19 11.6 0.1 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS79858.1 - 4.5e-05 23.5 3.6 0.082 12.8 0.1 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 ETS79858.1 - 4.8e-05 23.1 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS79858.1 - 9.8e-05 22.4 0.2 1.3 9.2 0.0 3.4 4 0 0 4 4 3 2 RNA helicase Arch_ATPase PF01637.13 ETS79858.1 - 0.00012 21.9 0.3 0.27 10.8 0.0 3.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 ETS79858.1 - 0.00012 21.5 0.0 0.44 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 ETS79858.1 - 0.00014 21.0 0.2 0.11 11.5 0.0 3.7 3 1 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 ETS79858.1 - 0.00016 21.5 0.0 1.1 9.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS79858.1 - 0.0007 19.4 0.0 0.94 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS79858.1 - 0.0011 18.5 0.9 1.5 8.1 0.1 3.1 4 0 0 4 4 4 2 AAA-like domain NB-ARC PF00931.17 ETS79858.1 - 0.0083 15.0 0.2 0.96 8.2 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 ETS79858.1 - 0.01 14.9 0.0 1.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) MobB PF03205.9 ETS79858.1 - 0.012 15.3 0.1 0.86 9.3 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 ETS79858.1 - 0.012 14.5 0.5 1.5 7.6 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 ETS79858.1 - 0.016 14.6 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 ETS79858.1 - 0.023 14.5 0.7 1.1 9.2 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 ETS79858.1 - 0.041 13.7 0.2 12 5.7 0.0 3.4 3 1 1 4 4 4 0 Dynamin family DUF815 PF05673.8 ETS79858.1 - 0.053 12.4 0.1 2.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF4458 PF14660.1 ETS79858.1 - 0.055 13.4 0.4 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) PduV-EutP PF10662.4 ETS79858.1 - 0.06 12.8 0.2 6.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2156 PF09924.4 ETS79858.1 - 0.078 11.7 0.2 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) NTPase_1 PF03266.10 ETS79858.1 - 0.095 12.4 1.2 9.6 5.8 0.0 3.0 3 0 0 3 3 2 0 NTPase DUF3987 PF13148.1 ETS79858.1 - 0.3 9.5 2.4 27 3.1 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Lipase_GDSL PF00657.17 ETS79860.1 - 1.9e-11 44.2 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS79860.1 - 1e-08 35.5 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 ETS79860.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M16_C PF05193.16 ETS79861.1 - 3.8e-21 75.5 0.0 4.9e-16 58.9 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 ETS79861.1 - 2.2e-07 30.7 0.4 2e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Zw10 PF06248.8 ETS79862.1 - 3.4e-14 51.9 0.6 1.1e-12 46.9 0.4 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 ETS79862.1 - 6e-06 25.6 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal ArsR PF09824.4 ETS79862.1 - 0.049 12.9 1.3 0.27 10.5 0.0 2.7 3 0 0 3 3 3 0 ArsR transcriptional regulator MutS_III PF05192.13 ETS79862.1 - 0.27 10.9 2.6 0.41 10.4 0.4 2.5 2 1 0 2 2 2 0 MutS domain III MARVEL PF01284.18 ETS79866.1 - 2.6e-05 24.0 8.0 0.00011 22.0 5.5 1.9 1 1 0 1 1 1 1 Membrane-associating domain CC2D2AN-C2 PF15625.1 ETS79869.1 - 0.19 11.2 1.1 0.26 10.7 0.8 1.3 1 1 0 1 1 1 0 CC2D2A N-terminal C2 domain DUF4614 PF15391.1 ETS79869.1 - 0.77 9.4 8.0 0.99 9.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 ETS79869.1 - 1.8 7.9 8.6 2 7.8 6.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) AAA PF00004.24 ETS79870.1 - 1e-52 177.8 0.0 3.1e-42 143.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 ETS79870.1 - 3.2e-07 29.9 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 ETS79870.1 - 6.8e-07 29.4 0.1 0.00063 19.7 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 ETS79870.1 - 1.2e-06 28.4 0.0 0.009 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS79870.1 - 1.8e-06 28.1 0.0 0.0016 18.6 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 ETS79870.1 - 5.3e-06 26.4 0.0 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETS79870.1 - 0.00018 21.2 0.1 0.0062 16.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS79870.1 - 0.00023 21.0 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS79870.1 - 0.00038 21.2 0.0 0.018 15.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS79870.1 - 0.00041 20.0 0.2 0.038 13.7 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 ETS79870.1 - 0.0045 16.0 0.0 0.045 12.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 ETS79870.1 - 0.0055 15.4 0.0 0.0096 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 ETS79870.1 - 0.0058 16.7 0.0 0.035 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 ETS79870.1 - 0.0063 15.7 0.1 0.13 11.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS79870.1 - 0.014 15.7 0.0 0.052 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS79870.1 - 0.016 14.6 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 ETS79870.1 - 0.016 15.2 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Bromodomain PF00439.20 ETS79870.1 - 0.048 13.5 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Bromodomain NACHT PF05729.7 ETS79870.1 - 0.063 12.9 0.2 0.69 9.5 0.1 2.9 3 1 0 3 3 2 0 NACHT domain AAA_3 PF07726.6 ETS79870.1 - 0.072 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 ETS79870.1 - 0.074 11.9 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 ETS79870.1 - 0.1 11.4 0.0 8.8 5.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 ETS79870.1 - 0.19 11.1 0.0 3.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain adh_short PF00106.20 ETS79871.1 - 6.8e-33 113.9 1.7 1.1e-32 113.3 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79871.1 - 9.6e-32 110.6 0.1 1.1e-31 110.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79871.1 - 3.4e-14 52.9 0.2 4.4e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 ETS79871.1 - 1.9e-05 24.5 0.1 3.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETS79871.1 - 3.7e-05 22.7 0.1 4.7e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS79871.1 - 0.00014 21.4 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS79871.1 - 0.00023 20.8 1.8 0.00034 20.3 0.4 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4347 PF14252.1 ETS79871.1 - 0.07 12.6 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) NAD_binding_10 PF13460.1 ETS79871.1 - 0.087 12.8 0.8 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 ETS79871.1 - 0.093 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bac_luciferase PF00296.15 ETS79872.1 - 2.1e-58 197.8 1.7 3.1e-58 197.3 1.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HTH_38 PF13936.1 ETS79872.1 - 0.57 9.7 1.9 0.65 9.5 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Aa_trans PF01490.13 ETS79873.1 - 2.4e-24 85.5 25.4 2.8e-24 85.3 17.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.24 ETS79874.1 - 1.1e-13 51.5 0.0 3.4e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS79874.1 - 0.039 14.1 0.3 0.27 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETS79874.1 - 0.12 12.0 0.0 0.41 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CorA PF01544.13 ETS79875.1 - 8.1e-06 25.0 5.3 1.8e-05 23.9 3.7 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PNP_UDP_1 PF01048.15 ETS79876.1 - 9.3e-13 47.6 0.1 4.7e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Metallophos_2 PF12850.2 ETS79876.1 - 0.034 13.9 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain CENP_C_N PF15622.1 ETS79879.1 - 0.0041 16.4 0.2 0.0069 15.6 0.2 1.2 1 0 0 1 1 1 1 Kinetochore assembly subunit CENP-C N-terminal Dynamin_N PF00350.18 ETS79880.1 - 7.9e-43 146.1 0.0 1.6e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS79880.1 - 1.3e-10 40.6 0.3 3.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 ETS79880.1 - 0.0014 18.5 0.1 0.022 14.7 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS79880.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 ETS79880.1 - 0.017 14.6 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation STAT_int PF02865.12 ETS79880.1 - 0.041 13.8 1.2 3.1 7.7 0.1 2.9 2 0 0 2 2 2 0 STAT protein, protein interaction domain SRI PF08236.6 ETS79880.1 - 0.056 13.3 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_16 PF13191.1 ETS79880.1 - 0.31 11.0 2.1 0.74 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain CTF_NFI PF00859.13 ETS79881.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region MMR_HSR1 PF01926.18 ETS79882.1 - 7.6e-20 71.0 0.1 3.2e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 ETS79882.1 - 4.7e-19 67.9 0.3 8.8e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 ETS79882.1 - 3.1e-13 49.2 0.0 5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS79882.1 - 3e-05 23.8 0.3 0.024 14.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 ETS79882.1 - 0.0037 17.7 0.0 0.0096 16.4 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ArgK PF03308.11 ETS79882.1 - 0.047 12.4 0.2 0.11 11.2 0.1 1.6 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 ETS79882.1 - 0.073 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_22 PF13401.1 ETS79882.1 - 0.082 13.0 0.0 0.87 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS79882.1 - 0.4 11.5 2.3 3.7 8.3 1.6 2.5 1 1 0 1 1 1 0 AAA domain Spo12 PF05032.7 ETS79883.1 - 1.3e-14 53.5 1.0 1.8e-14 53.0 0.2 1.7 2 0 0 2 2 2 1 Spo12 family DUF3226 PF11536.3 ETS79883.1 - 0.028 13.8 0.1 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Acyl-CoA_dh_1 PF00441.19 ETS79884.1 - 3.5e-28 98.5 0.1 5.6e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS79884.1 - 8.1e-17 60.4 0.0 2.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS79884.1 - 1.8e-14 54.1 0.1 4.4e-14 52.8 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS79884.1 - 1.6e-13 51.2 0.0 3.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain RRM_1 PF00076.17 ETS79885.1 - 6.7e-08 32.0 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79885.1 - 1.5e-07 31.1 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS79885.1 - 4.8e-05 23.0 0.0 9.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 ETS79885.1 - 8e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UreF PF01730.11 ETS79886.1 - 1.1e-11 45.0 0.2 1.1e-11 45.0 0.1 1.5 2 0 0 2 2 2 1 UreF Lzipper-MIP1 PF14389.1 ETS79886.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Cut12 PF11500.3 ETS79887.1 - 4.9e-38 130.1 16.6 4.9e-38 130.1 11.5 5.3 3 1 2 5 5 5 1 Spindle pole body formation-associated protein Bacillus_HBL PF05791.6 ETS79887.1 - 0.12 11.7 17.7 0.02 14.2 5.9 2.8 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 ETS79887.1 - 2.4 7.2 5.5 1.2 8.2 0.9 2.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein HGTP_anticodon2 PF12745.2 ETS79888.1 - 3.7e-71 239.4 0.8 3.7e-71 239.4 0.6 2.5 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 ETS79888.1 - 1.2e-66 224.5 0.0 1.6e-31 109.4 0.0 4.7 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79888.1 - 1.2e-38 132.6 0.0 3.8e-14 52.3 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 ETS79888.1 - 1.2e-12 47.5 0.9 2e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 ETS79888.1 - 1.3e-11 44.4 0.0 4.2e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 RWD domain APH PF01636.18 ETS79888.1 - 1.3e-05 25.0 2.9 0.081 12.6 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 ETS79888.1 - 0.16 10.6 0.1 11 4.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF1996 PF09362.5 ETS79889.1 - 7.4e-67 225.4 1.1 1.3e-66 224.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 ETS79889.1 - 8.4e-54 179.4 58.5 1.8e-21 75.8 8.8 3.7 3 0 0 3 3 3 3 WSC domain Sugar_tr PF00083.19 ETS79890.1 - 2.8e-94 316.2 22.7 3.3e-94 316.0 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS79890.1 - 1.1e-14 53.9 34.6 8.5e-12 44.4 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 ETS79891.1 - 3.4e-47 158.7 4.3 7.4e-19 67.8 0.2 5.3 3 1 1 5 5 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79891.1 - 4.5e-38 127.1 14.3 2e-05 24.1 0.2 9.1 9 0 0 9 9 8 6 Ankyrin repeat Ank_3 PF13606.1 ETS79891.1 - 1.6e-29 98.9 8.5 0.00037 20.4 0.1 8.7 9 0 0 9 9 7 7 Ankyrin repeat Ank_4 PF13637.1 ETS79891.1 - 4.6e-29 100.2 3.6 9.8e-11 41.8 0.1 5.4 4 1 1 5 5 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79891.1 - 8.5e-27 92.5 2.4 3.5e-07 30.2 0.1 7.6 2 1 5 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 ETS79891.1 - 1.6e-05 24.6 0.5 0.021 14.4 0.1 2.5 2 0 0 2 2 2 2 NACHT domain PGAP1 PF07819.8 ETS79891.1 - 1.7e-05 24.5 0.0 4.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.1 ETS79891.1 - 0.00023 21.1 0.1 0.05 13.5 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 ETS79891.1 - 0.00075 19.2 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF676 PF05057.9 ETS79891.1 - 0.0019 17.5 0.1 0.017 14.3 0.1 2.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 ETS79891.1 - 0.0021 18.1 0.0 0.034 14.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS79891.1 - 0.0068 16.7 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS79891.1 - 0.0091 16.8 0.0 0.044 14.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 ETS79891.1 - 0.019 14.1 0.0 0.066 12.3 0.0 1.9 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Abhydrolase_5 PF12695.2 ETS79891.1 - 0.021 14.5 0.0 0.22 11.3 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family AAA_33 PF13671.1 ETS79891.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS79891.1 - 0.041 13.3 0.2 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 ETS79891.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETS79891.1 - 0.057 13.1 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS79891.1 - 0.064 13.4 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 ETS79891.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 ETS79891.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain QueF PF14489.1 ETS79891.1 - 0.11 12.4 0.2 23 5.0 0.0 2.6 2 0 0 2 2 2 0 QueF-like protein AAA PF00004.24 ETS79891.1 - 0.13 12.4 0.0 0.75 10.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ETS79891.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PUL PF08324.6 ETS79893.1 - 4.1e-44 150.3 0.0 6.4e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 ETS79893.1 - 1.3e-34 119.1 0.0 2.3e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 ETS79893.1 - 2.7e-16 59.1 0.0 5.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS79893.1 - 1.2e-05 25.5 0.2 6.5e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 ETS79893.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 ETS79893.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein DUF2847 PF11009.3 ETS79893.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AhpC-TSA PF00578.16 ETS79893.1 - 0.031 13.9 0.1 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 AhpC/TSA family Redoxin PF08534.5 ETS79893.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Redoxin GDA1_CD39 PF01150.12 ETS79894.1 - 5.3e-98 328.3 0.0 6.9e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_3 PF07726.6 ETS79895.1 - 0.0051 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Metal_resist PF13801.1 ETS79896.1 - 0.0093 15.9 4.0 0.022 14.7 0.2 2.2 2 0 0 2 2 2 2 Heavy-metal resistance Spb1_C PF07780.7 ETS79897.1 - 1.5e-75 253.4 26.9 1.5e-75 253.4 18.7 3.9 2 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 ETS79897.1 - 8.9e-57 191.0 12.2 8.9e-57 191.0 8.4 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 ETS79897.1 - 5.2e-54 182.9 0.0 1.1e-53 181.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.27 ETS79898.1 - 1.2e-22 78.8 9.2 1.3e-07 31.2 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 ETS79898.1 - 0.19 9.9 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Heme_oxygenase PF01126.15 ETS79899.1 - 1.4e-12 47.5 0.0 3.7e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Heme oxygenase Integrase_1 PF12835.2 ETS79899.1 - 0.00012 21.8 0.4 0.00024 20.9 0.3 1.4 1 0 0 1 1 1 1 Integrase TRI12 PF06609.8 ETS79900.1 - 4.1e-54 183.8 25.6 5.4e-54 183.4 17.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS79900.1 - 4.6e-24 84.7 59.9 1.9e-22 79.5 38.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS79900.1 - 2.1e-12 46.3 15.5 2.1e-12 46.3 10.7 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter Ebp2 PF05890.7 ETS79901.1 - 1.8e-93 312.7 18.1 1.8e-93 312.7 12.5 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Ras PF00071.17 ETS79902.1 - 3.8e-55 185.6 0.0 4.6e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS79902.1 - 2e-18 66.9 0.0 3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS79902.1 - 6.4e-13 48.3 0.0 7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS79902.1 - 5.1e-08 32.8 0.0 7.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS79902.1 - 1.2e-07 31.1 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS79902.1 - 4.1e-06 26.3 0.0 0.00012 21.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 ETS79902.1 - 0.00077 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETS79902.1 - 0.0011 18.1 0.1 0.002 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 ETS79902.1 - 0.0014 18.3 0.0 0.0049 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 ETS79902.1 - 0.002 17.4 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 ETS79902.1 - 0.0042 16.6 0.2 0.14 11.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 ETS79902.1 - 0.0046 16.5 0.1 0.008 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS79902.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 ETS79902.1 - 0.0066 16.4 0.0 0.0079 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 ETS79902.1 - 0.007 15.8 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Septin PF00735.13 ETS79902.1 - 0.016 14.2 0.1 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Septin MobB PF03205.9 ETS79902.1 - 0.024 14.3 0.1 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 ETS79902.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 ETS79902.1 - 0.029 13.8 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 ETS79902.1 - 0.038 13.4 0.1 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 ETS79902.1 - 0.059 13.5 0.1 0.28 11.3 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 ETS79902.1 - 0.086 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain EamA PF00892.15 ETS79903.1 - 6.4e-09 35.9 29.6 1.1e-06 28.7 2.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 ETS79903.1 - 1.5e-05 25.1 2.9 1.5e-05 25.1 2.0 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 ETS79903.1 - 4.1e-05 22.5 5.8 4.1e-05 22.5 4.1 1.9 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 ETS79903.1 - 8.7e-05 22.2 22.0 0.00029 20.5 0.3 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 ETS79903.1 - 0.00025 20.0 7.7 0.00047 19.1 5.3 1.4 1 0 0 1 1 1 1 UAA transporter family DUF4252 PF14060.1 ETS79903.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Cyanate_lyase PF02560.9 ETS79904.1 - 3.9e-31 106.3 0.0 5.4e-31 105.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 ETS79904.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 ETS79904.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4_2 PF08281.7 ETS79904.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Utp14 PF04615.8 ETS79905.1 - 5 5.1 14.3 6.4 4.8 9.9 1.2 1 0 0 1 1 1 0 Utp14 protein DUF1754 PF08555.5 ETS79906.1 - 4.8e-10 39.9 15.3 4.8e-10 39.9 10.6 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) LIN37 PF15306.1 ETS79906.1 - 0.31 10.9 7.1 0.43 10.5 5.0 1.2 1 0 0 1 1 1 0 LIN37 Adaptin_binding PF10199.4 ETS79906.1 - 0.96 9.7 9.4 1.3 9.2 6.5 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 MAT1 PF06391.8 ETS79906.1 - 3.8 7.0 9.9 6.2 6.3 6.8 1.4 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 U79_P34 PF03064.11 ETS79906.1 - 5.4 6.4 10.8 7.1 6.0 7.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP PF01161.15 ETS79908.1 - 6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Milton PF12448.3 ETS79908.1 - 1.5 8.9 8.1 11 6.1 5.6 2.1 1 1 0 1 1 1 0 Kinesin associated protein Ribosomal_L4 PF00573.17 ETS79909.1 - 6e-48 162.7 0.0 8e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rep_fac-A_3 PF08661.6 ETS79910.1 - 7e-21 74.1 0.4 7.8e-21 74.0 0.3 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 bZIP_2 PF07716.10 ETS79911.1 - 4e-08 32.9 5.0 7.9e-08 32.0 3.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS79911.1 - 5.7e-08 32.6 6.2 1e-07 31.7 4.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 ETS79911.1 - 0.0034 17.6 2.0 0.0074 16.5 1.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor cobW PF02492.14 ETS79913.1 - 9.4e-38 129.4 0.0 1.2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 ETS79913.1 - 0.003 17.2 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 ETS79913.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS79913.1 - 0.025 14.3 0.1 0.066 12.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 ETS79913.1 - 0.041 13.4 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS79913.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS79913.1 - 0.059 13.6 0.9 0.17 12.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS79913.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CobW_C PF07683.9 ETS79913.1 - 0.079 12.6 0.0 2.4 7.9 0.0 2.9 2 2 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain NTPase_1 PF03266.10 ETS79913.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 ETS79913.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GFO_IDH_MocA PF01408.17 ETS79916.1 - 3.4e-31 108.2 1.1 5.2e-31 107.6 0.8 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS79916.1 - 7.4e-12 45.0 0.0 2.3e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 ETS79916.1 - 2.9e-08 34.0 1.4 5.4e-08 33.2 0.9 1.4 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.1 ETS79916.1 - 0.0001 22.4 0.5 0.00021 21.4 0.3 1.5 1 0 0 1 1 1 1 CoA binding domain Semialdhyde_dh PF01118.19 ETS79916.1 - 0.00015 22.0 0.3 0.0003 21.0 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS79916.1 - 0.0029 17.4 0.1 0.0045 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.19 ETS79916.1 - 0.0036 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 ETS79916.1 - 0.0081 14.9 1.3 0.012 14.4 0.9 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Pyr_redox_2 PF07992.9 ETS79916.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS79916.1 - 0.035 13.7 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS79916.1 - 0.044 12.9 0.1 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 ETS79916.1 - 0.06 13.7 0.8 0.12 12.8 0.5 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 ETS79916.1 - 0.15 11.5 0.6 0.54 9.7 0.4 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.17 ETS79917.1 - 5e-41 140.7 0.1 7.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_39 PF01229.12 ETS79918.1 - 0.00022 19.7 0.1 0.0003 19.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 MFS_1 PF07690.11 ETS79919.1 - 9.7e-27 93.5 31.0 1.1e-26 93.4 20.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 ETS79919.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.4 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF4387 PF14330.1 ETS79920.1 - 2e-37 127.4 0.0 9.3e-37 125.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 ETS79920.1 - 3.7e-19 68.4 0.0 1.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1446) DUF3129 PF11327.3 ETS79922.1 - 1.4e-48 165.1 8.3 1.6e-48 164.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Ank_2 PF12796.2 ETS79923.1 - 2.6e-103 338.5 17.0 5.2e-17 61.9 0.0 17.2 5 2 11 16 16 16 14 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79923.1 - 4.3e-83 269.2 26.3 1.1e-08 34.4 0.0 24.8 24 2 1 25 25 25 13 Ankyrin repeat Ank_4 PF13637.1 ETS79923.1 - 3e-65 215.5 39.5 6.5e-05 23.3 0.0 24.4 16 9 12 28 28 28 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79923.1 - 3.6e-53 172.2 21.8 4.3e-07 29.5 0.0 23.7 26 2 0 26 26 26 10 Ankyrin repeat Ank_5 PF13857.1 ETS79923.1 - 4.3e-53 176.1 51.6 4.3e-08 33.1 0.0 21.8 18 4 5 23 23 23 14 Ankyrin repeats (many copies) NACHT PF05729.7 ETS79923.1 - 2.1e-09 37.2 0.0 5.8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS79923.1 - 4.1e-06 26.8 0.3 4e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS79923.1 - 0.0016 18.5 0.0 0.0091 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETS79923.1 - 0.33 9.8 0.0 0.68 8.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Shigella_OspC PF06128.6 ETS79923.1 - 1.1 8.6 2.9 24 4.3 0.0 3.8 4 0 0 4 4 4 0 Shigella flexneri OspC protein HET PF06985.6 ETS79924.1 - 3.4e-29 101.7 2.9 7.3e-29 100.7 2.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PBP1_TM PF14812.1 ETS79924.1 - 0.46 10.8 4.4 1.2 9.5 3.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NACHT PF05729.7 ETS79925.1 - 7.8e-11 41.9 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS79925.1 - 2e-06 27.9 0.2 1.3e-05 25.3 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS79925.1 - 6.9e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS79925.1 - 0.00088 19.4 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS79925.1 - 0.0029 17.3 0.1 0.014 15.1 0.1 2.2 1 1 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETS79925.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain eIF2A PF08662.6 ETS79925.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A APS_kinase PF01583.15 ETS79925.1 - 0.085 12.5 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.12 ETS79925.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 ETS79925.1 - 0.11 11.4 0.0 0.25 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 ETS79925.1 - 0.12 11.2 0.1 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 ETS79925.1 - 0.14 12.9 0.0 0.4 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 ETS79926.1 - 9.2e-16 58.2 0.0 1.6e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS79926.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS79926.1 - 0.0053 16.8 0.1 0.12 12.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS79926.1 - 0.0078 16.2 6.2 0.23 11.4 3.9 3.1 2 1 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 ETS79926.1 - 0.022 14.2 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 ETS79926.1 - 0.05 14.4 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETS79926.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 ETS79926.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 ETS79926.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 ETS79926.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.16 ETS79926.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4570 PF15134.1 ETS79927.1 - 0.0014 18.4 0.1 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Toxin_39 PF15500.1 ETS79927.1 - 0.083 13.0 0.1 0.31 11.1 0.1 2.0 1 0 0 1 1 1 0 Putative RNase-like toxin MIP-T3 PF10243.4 ETS79927.1 - 2.3 6.5 20.9 4.9 5.5 14.5 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Arginase PF00491.16 ETS79928.1 - 9.9e-29 100.4 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Tannase PF07519.6 ETS79929.1 - 2.1e-93 313.6 0.9 2.4e-93 313.4 0.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS79929.1 - 7e-08 32.6 0.2 4.8e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS79929.1 - 1.1e-06 28.0 0.3 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS79929.1 - 0.00066 19.4 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS79929.1 - 0.032 13.8 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_12 PF13424.1 ETS79931.1 - 7.2e-54 179.6 9.1 1.1e-13 50.8 0.1 4.6 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETS79931.1 - 4.1e-41 137.7 6.3 1.1e-09 37.8 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat HET PF06985.6 ETS79931.1 - 7.7e-20 71.4 7.7 8.3e-17 61.6 5.4 3.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 ETS79931.1 - 2.2e-18 65.6 1.6 6.2e-08 32.1 0.5 5.3 1 1 4 6 6 6 4 TPR repeat TPR_1 PF00515.23 ETS79931.1 - 1.2e-15 56.3 9.0 7.8e-06 25.2 0.4 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS79931.1 - 6.4e-15 53.7 5.5 5e-06 25.9 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS79931.1 - 6.4e-15 53.7 9.3 0.0011 18.6 0.2 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS79931.1 - 2.5e-12 46.2 6.9 0.021 15.4 0.0 7.0 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS79931.1 - 2.6e-12 47.0 1.7 0.00015 22.3 0.1 5.2 2 2 4 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 ETS79931.1 - 4.6e-12 45.3 0.0 7.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 ETS79931.1 - 4.6e-09 35.7 0.3 1.6 9.0 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS79931.1 - 1.4e-08 34.3 1.7 0.014 15.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS79931.1 - 1.8e-07 31.1 2.4 0.0017 18.4 0.3 3.8 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 ETS79931.1 - 3.6e-07 29.5 10.6 0.026 14.2 0.7 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 ETS79931.1 - 2.3e-06 27.2 1.8 0.00043 20.0 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS79931.1 - 5.3e-06 26.6 7.7 0.63 10.4 0.0 5.5 2 2 3 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.1 ETS79931.1 - 0.00014 22.0 0.4 0.0016 18.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Coatomer_E PF04733.9 ETS79931.1 - 0.00018 20.8 1.0 0.055 12.6 0.2 2.6 2 0 0 2 2 2 2 Coatomer epsilon subunit PPR PF01535.15 ETS79931.1 - 0.0021 17.8 6.1 3.6 7.7 0.1 5.7 5 0 0 5 5 5 1 PPR repeat MIT PF04212.13 ETS79931.1 - 0.014 15.2 0.5 0.18 11.7 0.1 3.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain DUF1955 PF09205.5 ETS79931.1 - 0.028 13.9 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_5 PF12688.2 ETS79931.1 - 0.03 14.3 0.6 7.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat SNAP PF14938.1 ETS79931.1 - 0.031 13.4 1.1 0.66 9.0 0.0 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP AAA_25 PF13481.1 ETS79931.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_21 PF09976.4 ETS79931.1 - 0.14 12.1 3.2 0.34 10.8 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS79931.1 - 0.2 12.1 13.1 4.4 7.9 0.6 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3328 PF11807.3 ETS79932.1 - 0.6 9.7 6.6 4.9 6.7 4.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Pkinase PF00069.20 ETS79934.1 - 3.6e-59 200.0 0.0 6.3e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79934.1 - 2.1e-20 72.9 0.0 9.5e-20 70.7 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 ETS79934.1 - 0.0099 15.2 0.1 0.14 11.5 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.6 ETS79934.1 - 0.066 12.0 0.2 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mtc PF03820.12 ETS79935.1 - 1.9e-103 345.3 0.1 1.4e-102 342.4 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier Beta-lactamase PF00144.19 ETS79936.1 - 1.2e-36 126.4 0.0 1.5e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETS79936.1 - 0.021 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.17 ETS79937.1 - 2.4e-34 118.6 0.1 5.2e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF1217 PF06748.7 ETS79939.1 - 0.085 12.9 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) CENP-T PF15511.1 ETS79940.1 - 0.0044 16.3 2.1 0.0094 15.2 1.5 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Pkinase PF00069.20 ETS79942.1 - 1.2e-63 214.7 0.0 2e-63 213.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79942.1 - 1.3e-26 93.2 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 ETS79942.1 - 0.014 14.7 0.0 0.09 12.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.1 ETS79942.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETS79942.1 - 0.055 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_L_2 PF13656.1 ETS79944.1 - 8.4e-27 92.4 0.0 5.4e-26 89.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 ETS79944.1 - 2.6e-08 32.8 0.0 1.2e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR PF05347.10 ETS79945.1 - 2.1e-06 27.4 0.1 4.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS79945.1 - 6.1e-05 23.1 0.4 0.00018 21.6 0.1 1.9 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 ETS79945.1 - 6.2e-05 23.4 0.1 8.2e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like G10 PF01125.12 ETS79946.1 - 7.8e-60 200.6 6.6 8.7e-60 200.4 4.6 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2 PF00096.21 ETS79947.1 - 0.25 11.7 13.1 0.15 12.4 2.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS79947.1 - 0.52 10.7 14.4 1.7 9.1 2.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.4 ETS79948.1 - 5.1e-42 143.9 0.2 8.7e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 ETS79948.1 - 3.5e-21 75.5 0.1 8.1e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.19 ETS79949.1 - 3e-64 217.0 0.6 3.5e-64 216.8 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ETS79949.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TcpA PF05946.7 ETS79949.1 - 0.026 14.3 0.1 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Ribosomal_L2_C PF03947.13 ETS79950.1 - 1.1e-37 128.7 3.5 1.1e-37 128.7 2.4 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ETS79950.1 - 1.2e-13 50.7 0.1 2.4e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.17 ETS79951.1 - 5.4e-06 25.9 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79951.1 - 0.00045 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79951.1 - 0.0085 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 ETS79952.1 - 1.4e-52 178.4 0.0 2.9e-52 177.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79952.1 - 1.5e-23 83.1 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS79952.1 - 0.00023 20.9 1.6 0.0005 19.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETS79952.1 - 0.0032 16.8 0.2 0.01 15.1 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 ETS79952.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Choline_kinase PF01633.15 ETS79952.1 - 0.36 10.3 1.6 0.49 9.9 0.2 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.17 ETS79953.1 - 1.5e-62 207.1 0.0 1.1e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79953.1 - 3.4e-46 155.1 0.0 2e-15 56.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79953.1 - 1.1e-33 114.7 0.0 1.8e-11 43.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS79953.1 - 2.6e-07 30.2 0.0 0.0032 17.1 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 ETS79953.1 - 0.002 18.0 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RNA_bind PF08675.6 ETS79953.1 - 0.035 14.0 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain RRM_3 PF08777.6 ETS79953.1 - 0.068 13.0 0.0 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif Aldo_ket_red PF00248.16 ETS79955.1 - 9.1e-58 195.3 0.0 1e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2016 PF09436.5 ETS79955.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) DUF3425 PF11905.3 ETS79956.1 - 1.8e-31 108.8 2.5 1.8e-31 108.8 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS79956.1 - 0.53 10.2 8.3 1 9.3 5.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.18 ETS79957.1 - 7.8e-17 61.0 0.1 1.7e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS79957.1 - 0.014 15.3 0.1 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Berberine and berberine like Cellulase PF00150.13 ETS79958.1 - 6.9e-17 61.5 2.6 1.4e-16 60.5 1.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PH PF00169.24 ETS79959.1 - 7.9e-30 103.1 2.2 2.6e-17 62.8 0.4 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 ETS79959.1 - 1.5e-11 44.4 3.4 1.8e-05 24.8 0.7 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 ETS79959.1 - 3.3e-10 40.2 5.2 3.7e-07 30.3 0.3 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 ETS79959.1 - 2.1e-05 24.5 0.1 5.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 ETS79959.1 - 0.0003 20.6 1.3 0.0064 16.3 0.1 2.5 2 1 0 2 2 2 1 PH domain PH_4 PF15404.1 ETS79959.1 - 0.076 12.5 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Tmemb_170 PF10190.4 ETS79961.1 - 0.0017 18.4 9.4 0.0021 18.0 6.5 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep_2 PF14602.1 ETS79962.1 - 9.1e-14 50.7 9.5 2.5e-11 42.9 3.1 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 ETS79962.1 - 6.6e-13 47.5 11.4 5e-10 38.4 3.3 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 ETS79962.1 - 7.9e-09 35.4 0.3 1.2e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Acetyltransf_11 PF13720.1 ETS79962.1 - 0.087 13.0 0.2 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ICMT PF04140.9 ETS79963.1 - 3.7e-28 97.5 0.3 3.7e-28 97.5 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS79963.1 - 1.1e-16 60.8 2.1 1.1e-16 60.8 1.5 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 ETS79963.1 - 1.1e-06 28.1 1.2 1.7e-06 27.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 ETS79963.1 - 1e-05 24.3 1.7 1.4e-05 23.8 0.1 1.8 1 1 1 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family DUF973 PF06157.6 ETS79963.1 - 0.003 16.5 0.9 0.004 16.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Scs3p PF10261.4 ETS79963.1 - 0.023 13.7 0.1 0.053 12.5 0.1 1.5 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1469 PF07332.6 ETS79963.1 - 5.7 6.6 10.4 0.32 10.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ank PF00023.25 ETS79964.1 - 1.4e-106 343.3 41.3 1.6e-09 37.0 0.0 18.2 19 0 0 19 19 19 13 Ankyrin repeat Ank_2 PF12796.2 ETS79964.1 - 9.8e-105 343.1 30.2 8.9e-16 58.0 0.0 11.5 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS79964.1 - 6.1e-79 258.2 47.1 3e-12 46.3 0.0 13.0 4 2 12 16 16 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79964.1 - 1.5e-75 241.4 32.6 5.5e-06 26.1 0.2 17.6 17 0 0 17 17 16 13 Ankyrin repeat Ank_4 PF13637.1 ETS79964.1 - 5.3e-69 227.4 43.1 7.6e-10 39.0 0.1 12.5 4 2 10 14 14 13 12 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 ETS79964.1 - 3.2e-16 59.0 0.0 6.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 ETS79964.1 - 7.8e-11 41.9 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS79964.1 - 8e-10 39.0 1.7 2.3e-09 37.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 ETS79964.1 - 0.00011 22.4 0.0 0.00086 19.5 0.0 2.7 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS79964.1 - 0.00097 19.2 0.0 0.0088 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS79964.1 - 0.0015 18.4 0.0 0.014 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 ETS79964.1 - 0.0016 17.3 0.0 0.0036 16.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Shigella_OspC PF06128.6 ETS79964.1 - 0.011 15.2 1.3 9.8 5.5 0.1 4.0 3 2 0 3 3 3 0 Shigella flexneri OspC protein RNA_helicase PF00910.17 ETS79964.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 ETS79964.1 - 0.049 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PDEase_I PF00233.14 ETS79965.1 - 2.2e-45 155.2 0.1 5.4e-41 140.8 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF3669 PF12417.3 ETS79966.1 - 5.1e-09 35.7 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Myb_DNA-binding PF00249.26 ETS79967.1 - 4.3e-06 26.6 0.0 8.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS79967.1 - 0.00012 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 ETS79968.1 - 2.3e-20 72.3 10.6 2.3e-20 72.3 7.3 6.5 4 2 1 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 ETS79968.1 - 5.1e-08 32.8 12.2 8.7e-08 32.0 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS79968.1 - 7.1e-07 28.7 13.4 1.3e-06 27.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS79968.1 - 7.5e-07 28.7 10.0 1.2e-06 28.0 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS79968.1 - 2.1e-06 27.3 13.2 3.6e-06 26.6 9.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 ETS79968.1 - 5.7e-06 26.0 9.1 1e-05 25.2 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 ETS79968.1 - 0.0001 22.0 3.6 0.00021 21.0 2.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 ETS79968.1 - 0.00026 20.6 7.6 0.0007 19.2 5.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETS79968.1 - 0.00097 18.9 8.1 0.0019 18.0 5.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Reo_sigmaC PF04582.7 ETS79968.1 - 0.0035 16.5 2.4 0.0035 16.5 1.7 4.3 1 1 1 4 4 4 2 Reovirus sigma C capsid protein zf-C2H2_6 PF13912.1 ETS79968.1 - 0.0095 15.8 1.0 0.9 9.5 0.0 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-RING_4 PF14570.1 ETS79968.1 - 0.015 14.8 7.9 0.038 13.5 5.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 ETS79968.1 - 0.026 14.0 3.3 0.048 13.2 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 ETS79968.1 - 0.051 13.6 5.2 0.15 12.1 3.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 ETS79968.1 - 0.42 10.1 7.0 0.9 9.1 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.21 ETS79968.1 - 0.54 10.7 5.1 21 5.7 0.1 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type FYVE PF01363.16 ETS79968.1 - 1.5 8.7 12.3 14 5.6 8.6 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-CHY PF05495.7 ETS79968.1 - 2.4 8.3 10.2 5.1 7.3 6.2 2.1 2 0 0 2 2 2 0 CHY zinc finger DUF1183 PF06682.7 ETS79969.1 - 4.1e-77 259.9 26.0 1.6e-76 257.9 18.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) p450 PF00067.17 ETS79970.1 - 6.5e-48 163.4 0.1 1.4e-47 162.2 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 Pkinase PF00069.20 ETS79971.1 - 1.3e-70 237.4 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS79971.1 - 2.9e-44 151.1 0.0 4.1e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS79971.1 - 6.3e-08 31.9 0.0 2.9e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS79971.1 - 0.0014 17.7 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS79971.1 - 0.0049 16.2 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETS79971.1 - 0.015 14.6 0.0 0.17 11.1 0.0 2.2 1 1 1 2 2 2 0 RIO1 family APH PF01636.18 ETS79971.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 ETS79972.1 - 7.5e-34 116.6 0.1 9.7e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 ETS79972.1 - 0.0064 16.1 2.1 0.0064 16.1 1.5 2.0 1 1 0 2 2 2 1 SprT-like family Ribosomal_L40e PF01020.12 ETS79972.1 - 0.29 10.7 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal L40e family AA_kinase PF00696.23 ETS79973.1 - 1.8e-38 132.4 1.4 2.7e-38 131.9 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 ETS79973.1 - 1.1e-12 47.4 1.0 3.5e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 PUA domain CsbD PF05532.7 ETS79974.1 - 0.037 13.6 0.5 0.067 12.8 0.4 1.4 1 0 0 1 1 1 0 CsbD-like Fungal_trans PF04082.13 ETS79975.1 - 1e-11 44.2 0.6 1.5e-11 43.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF637 PF04830.8 ETS79975.1 - 0.013 15.1 0.4 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) Ank_2 PF12796.2 ETS79976.1 - 5.7e-56 186.8 0.0 7.9e-12 45.3 0.0 5.8 2 1 4 6 6 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS79976.1 - 1.8e-42 141.0 0.1 5.9e-06 25.8 0.0 11.0 11 0 0 11 11 10 9 Ankyrin repeat Ank_4 PF13637.1 ETS79976.1 - 3.6e-35 119.7 5.6 1.8e-08 34.6 0.1 8.0 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS79976.1 - 1.5e-34 117.2 5.9 1.8e-08 34.3 0.0 8.5 3 2 7 10 10 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS79976.1 - 2.7e-30 101.4 0.1 0.045 13.9 0.0 10.2 10 0 0 10 10 9 6 Ankyrin repeat Abhydrolase_6 PF12697.2 ETS79976.1 - 7.1e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS79976.1 - 1.6e-06 27.9 0.0 4.7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 ETS79976.1 - 2.9e-05 23.7 0.0 0.00023 20.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.9 ETS79976.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 ETS79976.1 - 0.0008 19.5 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS79976.1 - 0.0012 18.8 0.1 0.034 14.1 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain Abhydrolase_5 PF12695.2 ETS79976.1 - 0.0014 18.4 0.0 0.0038 16.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family APS_kinase PF01583.15 ETS79976.1 - 0.0043 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase TrwB_AAD_bind PF10412.4 ETS79976.1 - 0.04 12.5 0.0 1.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.5 ETS79976.1 - 0.058 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 6PF2K PF01591.13 ETS79976.1 - 0.06 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 ETS79976.1 - 0.069 12.6 0.0 5 6.5 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 ETS79976.1 - 0.081 11.9 0.1 9.6 5.0 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 ETS79976.1 - 0.1 12.8 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 ETS79976.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MFS_1 PF07690.11 ETS79977.1 - 4.1e-33 114.5 23.0 1.7e-31 109.2 16.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS79977.1 - 0.0033 17.4 0.6 0.016 15.2 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) DUF4231 PF14015.1 ETS79977.1 - 7 6.6 8.1 18 5.3 1.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) AAT PF03417.11 ETS79978.1 - 1.4e-29 103.1 0.0 1.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 ETS79978.1 - 0.00084 19.6 0.4 0.0016 18.7 0.0 1.6 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Polysacc_deac_1 PF01522.16 ETS79979.1 - 1.6e-20 72.9 0.0 2.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 ETS79979.1 - 1.1e-06 28.2 0.1 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 ETS79979.1 - 1.5e-05 24.0 0.1 2.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 adh_short PF00106.20 ETS79980.1 - 1.2e-25 90.3 0.7 3.2e-25 88.9 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79980.1 - 2.2e-19 70.1 0.0 3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79980.1 - 2.7e-07 30.4 0.5 1.3e-06 28.2 0.4 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS79980.1 - 8.7e-07 28.6 0.0 1.4e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS79980.1 - 0.0017 17.1 0.1 0.0023 16.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Tobravirus_2B PF05271.6 ETS79980.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Tobravirus 2B protein DUF3426 PF11906.3 ETS79980.1 - 0.055 13.1 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) RmlD_sub_bind PF04321.12 ETS79980.1 - 0.09 11.6 0.0 0.22 10.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 ETS79981.1 - 2e-19 70.1 1.6 6.5e-19 68.4 1.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS79981.1 - 4.3e-15 56.1 0.0 6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS79981.1 - 6.9e-07 29.1 0.6 4.8e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS79981.1 - 0.00058 19.3 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 ETS79981.1 - 0.0047 16.7 0.1 0.0089 15.8 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS79981.1 - 0.048 13.6 0.2 0.52 10.3 0.1 2.3 3 0 0 3 3 3 0 NADH(P)-binding Acyltransferase PF01553.16 ETS79982.1 - 1.1e-34 118.6 0.0 1.7e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4281 PF14108.1 ETS79982.1 - 0.013 15.6 1.4 0.027 14.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Phage_CP76 PF06892.6 ETS79982.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) AP_endonuc_2 PF01261.19 ETS79985.1 - 5.9e-24 84.5 0.0 7.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel OrfB_IS605 PF01385.14 ETS79985.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Probable transposase adh_short_C2 PF13561.1 ETS79986.1 - 6.7e-31 107.8 0.0 8e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS79986.1 - 3.1e-26 92.2 0.0 4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS79986.1 - 3.3e-10 39.9 0.1 5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS79986.1 - 7.2e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS79986.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 ETS79986.1 - 0.0025 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 ETS79986.1 - 0.0032 18.0 0.0 0.0053 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 ETS79986.1 - 0.0038 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 ETS79986.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 ETS79986.1 - 0.027 14.5 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding Ldh_1_N PF00056.18 ETS79986.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 ETS79986.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 ETS79986.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain FAD_binding_3 PF01494.14 ETS79986.1 - 0.12 11.4 0.4 3.4 6.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Eno-Rase_NADH_b PF12242.3 ETS79986.1 - 0.13 12.1 0.2 0.34 10.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 ETS79987.1 - 3.5e-98 329.1 34.8 1.7e-64 218.0 6.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS79987.1 - 5.2e-20 71.4 45.0 1.9e-10 40.0 15.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PX PF00787.19 ETS79988.1 - 1.2e-19 70.1 0.0 3.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 ETS79988.1 - 6.8e-17 61.5 11.4 1.4e-10 40.8 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Asp PF00026.18 ETS79989.1 - 1.2e-73 248.1 7.8 1.6e-73 247.7 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS79989.1 - 4.7e-11 42.8 1.1 4.7e-11 42.8 0.8 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS79989.1 - 5.4e-06 26.8 6.2 0.028 14.9 0.4 4.1 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 ETS79989.1 - 0.00019 21.0 0.1 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Glyco_tranf_2_4 PF13704.1 ETS79990.1 - 1.7e-11 44.2 0.0 4.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 ETS79990.1 - 0.00016 21.1 0.0 0.00056 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glycos_transf_2 PF00535.21 ETS79990.1 - 0.11 12.1 0.0 0.51 9.9 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 TPT PF03151.11 ETS79991.1 - 9.8e-16 57.7 12.6 9.8e-16 57.7 8.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS79991.1 - 1.5e-05 25.0 11.0 1.5e-05 25.0 7.6 2.8 2 2 0 2 2 2 1 EamA-like transporter family Epimerase PF01370.16 ETS79992.1 - 1.7e-56 191.3 0.0 2.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS79992.1 - 3.7e-23 81.8 0.0 3.4e-22 78.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS79992.1 - 4.6e-22 78.1 0.0 2.8e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 ETS79992.1 - 1.2e-20 73.3 0.0 1.9e-20 72.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS79992.1 - 5.3e-20 71.4 0.0 7.1e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS79992.1 - 6.7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS79992.1 - 0.027 14.4 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_23 PF13489.1 ETS79993.1 - 2.3e-17 63.1 0.0 4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS79993.1 - 1.1e-11 45.1 0.0 2.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS79993.1 - 4.9e-09 36.5 0.0 9.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS79993.1 - 4.1e-08 32.9 0.0 1.7e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS79993.1 - 1.5e-07 32.0 0.0 4.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS79993.1 - 0.00046 19.3 0.0 0.00091 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 ETS79993.1 - 0.0012 18.0 0.0 0.0047 16.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 ETS79993.1 - 0.0025 17.0 0.0 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase MTS PF05175.9 ETS79993.1 - 0.0062 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS79993.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 ETS79993.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 ETS79993.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 ETS79993.1 - 0.08 12.4 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.14 ETS79993.1 - 0.095 12.6 0.0 0.7 9.8 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase SelB-wing_1 PF09105.5 ETS79993.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Pep3_Vps18 PF05131.9 ETS79994.1 - 1.9e-46 157.1 0.9 3.5e-46 156.2 0.0 2.0 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 ETS79994.1 - 5.5e-10 38.9 13.2 4.6e-08 32.7 0.3 3.7 1 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 ETS79994.1 - 0.00019 21.2 1.4 0.00043 20.0 1.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS79994.1 - 0.00064 19.3 1.7 0.0014 18.2 1.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_19 PF14559.1 ETS79994.1 - 0.011 16.0 0.4 0.27 11.5 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Vps39_2 PF10367.4 ETS79994.1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DNA_pol3_theta PF06440.6 ETS79994.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, theta subunit zf-C3HC4_2 PF13923.1 ETS79994.1 - 0.11 12.4 1.5 0.29 11.1 1.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS79994.1 - 0.16 12.0 0.1 0.5 10.5 0.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger DUF2175 PF09943.4 ETS79994.1 - 0.32 11.0 4.7 0.077 13.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.20 ETS79994.1 - 3.6 7.3 6.5 0.35 10.5 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PUF PF00806.14 ETS79996.1 - 2.8e-27 92.6 0.0 0.00012 21.3 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 ETS79996.1 - 5.8e-13 48.2 0.0 1.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS79996.1 - 4.1e-08 32.9 0.0 7.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS79996.1 - 8.6e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 ETS79997.1 - 1.2e-12 47.2 23.9 2e-09 36.9 6.8 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 ETS79997.1 - 0.021 14.1 8.0 0.7 9.1 1.0 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 ETS79997.1 - 0.025 13.8 9.4 0.47 9.8 3.1 2.7 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 ETS79997.1 - 0.046 13.8 3.2 0.16 12.1 0.2 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain FAIM1 PF06905.8 ETS79997.1 - 0.14 11.3 0.1 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) C1_1 PF00130.17 ETS79997.1 - 2 8.1 14.2 0.17 11.5 0.5 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M24 PF00557.19 ETS79998.1 - 2.6e-11 43.4 0.0 3.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SNF5 PF04855.7 ETS79999.1 - 8.9e-74 248.0 0.4 1.6e-73 247.1 0.3 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pex14_N PF04695.8 ETS79999.1 - 9.8 6.2 14.0 14 5.7 2.1 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short PF00106.20 ETS80000.1 - 2.3e-20 73.1 0.0 3.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS80000.1 - 4.7e-06 26.3 0.0 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS80000.1 - 0.00043 20.3 0.0 0.00099 19.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS80000.1 - 0.0038 16.4 0.0 0.0065 15.6 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 ETS80000.1 - 0.057 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 ETS80000.1 - 0.095 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DSBA PF01323.15 ETS80001.1 - 1.8e-13 50.4 0.0 4.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Mod_r PF07200.8 ETS80002.1 - 0.0062 16.4 4.8 0.0062 16.4 3.3 1.5 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DUF2514 PF10721.4 ETS80002.1 - 0.039 13.6 5.9 0.058 13.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Gp-FAR-1 PF05823.7 ETS80002.1 - 0.049 13.5 3.9 0.066 13.1 2.7 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2458 PF10454.4 ETS80002.1 - 0.051 13.4 3.3 0.073 12.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Spectrin PF00435.16 ETS80002.1 - 0.12 12.6 7.2 0.18 12.0 5.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Mnd1 PF03962.10 ETS80002.1 - 0.46 10.1 8.0 0.72 9.4 5.6 1.3 1 0 0 1 1 1 0 Mnd1 family Synaptobrevin PF00957.16 ETS80002.1 - 0.6 9.7 3.3 7.3 6.2 0.2 2.3 1 1 1 2 2 2 0 Synaptobrevin Gly-zipper_OmpA PF13436.1 ETS80002.1 - 0.81 9.3 19.4 63 3.2 13.5 2.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain OmpH PF03938.9 ETS80002.1 - 3.3 7.6 12.6 5.8 6.8 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TraT PF05818.7 ETS80002.1 - 9.7 5.5 9.6 14 5.0 6.4 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein FadA PF09403.5 ETS80003.1 - 2.9 7.9 17.6 1.8 8.6 6.7 2.7 3 0 0 3 3 3 0 Adhesion protein FadA 4HB_MCP_1 PF12729.2 ETS80003.1 - 3 7.1 6.3 5 6.4 4.4 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2040 PF09745.4 ETS80004.1 - 4.5e-40 136.4 20.6 4.5e-40 136.4 14.3 3.9 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Fil_haemagg_2 PF13332.1 ETS80004.1 - 0.13 12.0 1.0 0.23 11.2 0.7 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat zf-Tim10_DDP PF02953.10 ETS80005.1 - 3.9e-22 77.3 0.8 4.6e-22 77.0 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Lectin_leg-like PF03388.8 ETS80006.1 - 2.2e-65 220.0 0.0 2.7e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 ETS80006.1 - 0.0028 17.0 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.5 ETS80006.1 - 0.027 13.7 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Pkinase PF00069.20 ETS80007.1 - 2.5e-71 239.9 0.4 5.1e-71 238.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80007.1 - 1.7e-38 132.1 0.0 2.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80007.1 - 1.5e-08 33.9 0.0 2.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETS80007.1 - 0.1 11.9 0.3 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PAT1 PF09770.4 ETS80007.1 - 2.1 6.5 39.3 2.5 6.2 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 ETS80007.1 - 4.9 6.9 31.6 6.7 6.4 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.13 ETS80008.1 - 2.7e-07 29.9 1.9 3.9e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF1318 PF07027.7 ETS80008.1 - 0.05 13.8 0.5 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Dynamin_N PF00350.18 ETS80009.1 - 4.5e-16 59.1 0.1 5.1e-15 55.7 0.0 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 ETS80009.1 - 6.4e-07 29.3 0.0 0.0001 22.1 0.0 3.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 ETS80009.1 - 0.00017 20.7 0.6 0.0031 16.6 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 ETS80009.1 - 0.0003 21.2 0.8 0.0087 16.5 0.0 3.4 3 1 1 4 4 4 1 Miro-like protein DUF258 PF03193.11 ETS80009.1 - 0.00031 19.9 0.0 0.0045 16.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 ETS80009.1 - 0.0026 16.4 0.0 0.005 15.5 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein ABC_tran PF00005.22 ETS80009.1 - 0.0039 17.4 1.4 0.011 15.9 0.1 2.5 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 ETS80009.1 - 0.079 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ELO PF01151.13 ETS80010.1 - 1.2e-83 280.2 9.4 1.5e-83 279.9 6.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF423 PF04241.10 ETS80010.1 - 0.54 10.2 7.0 1.1 9.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF423) FYVE PF01363.16 ETS80011.1 - 5.2e-15 55.0 8.8 9.3e-15 54.2 6.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 ETS80011.1 - 0.072 12.9 12.4 0.041 13.7 5.4 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 ETS80011.1 - 0.14 12.1 5.2 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain MoaC PF01967.16 ETS80012.1 - 1.9e-50 170.0 3.4 3.4e-50 169.2 2.3 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 ETS80012.1 - 3.1e-35 120.6 0.0 4e-34 117.0 0.0 2.3 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 ETS80012.1 - 6.2e-20 72.0 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 ETS80012.1 - 0.00014 22.0 0.0 0.00044 20.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 ETS80012.1 - 0.00021 21.2 0.0 0.00065 19.7 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain RRM_6 PF14259.1 ETS80014.1 - 2.4e-11 43.4 0.0 1.3e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS80014.1 - 1.2e-08 34.4 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS80014.1 - 3.7e-06 26.6 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 ETS80014.1 - 0.028 14.1 0.1 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Dynamin_N PF00350.18 ETS80015.1 - 1.2e-15 57.7 0.0 1.2e-14 54.5 0.0 2.8 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 ETS80015.1 - 0.00011 22.0 0.0 0.065 13.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.22 ETS80015.1 - 0.00013 22.2 0.3 0.0085 16.3 0.0 3.0 2 0 0 2 2 2 1 ABC transporter Adeno_IVa2 PF02456.10 ETS80015.1 - 0.00043 19.0 0.0 0.00091 17.9 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein DUF258 PF03193.11 ETS80015.1 - 0.0016 17.6 0.0 0.055 12.6 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Miro PF08477.8 ETS80015.1 - 0.016 15.6 0.0 0.069 13.6 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 ETS80015.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 ETS80015.1 - 0.065 13.0 5.4 0.56 9.9 0.0 3.7 2 1 1 3 3 3 0 Domain of unknown function DUF87 NUDIX_2 PF13869.1 ETS80016.1 - 8.4e-81 269.7 0.0 9.9e-81 269.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 ETS80017.1 - 3e-36 123.8 0.0 2.6e-35 120.7 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF3328 PF11807.3 ETS80017.1 - 0.18 11.4 0.6 0.25 10.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) zf-CHCC PF10276.4 ETS80018.1 - 3.8e-15 55.4 1.1 5.5e-15 54.9 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 ETS80018.1 - 0.064 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb zf-CCHC PF00098.18 ETS80019.1 - 2.7e-05 23.8 5.1 5.4e-05 22.9 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop14 PF04147.7 ETS80019.1 - 0.07 11.0 10.6 0.093 10.6 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family zf-CCHC_4 PF14392.1 ETS80019.1 - 0.3 10.7 2.5 0.64 9.7 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.9 ETS80019.1 - 5.4 4.9 18.2 0.037 12.0 5.8 1.9 2 0 0 2 2 2 0 CDC45-like protein Herpes_LMP2 PF07415.6 ETS80019.1 - 6.6 5.1 4.7 11 4.4 3.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ebola_NP PF05505.7 ETS80019.1 - 7.4 4.5 10.8 2.8 5.8 3.5 2.1 2 0 0 2 2 2 0 Ebola nucleoprotein Peptidase_M16 PF00675.15 ETS80020.1 - 2.7e-34 118.0 0.1 9.3e-34 116.3 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS80020.1 - 1.2e-26 93.5 0.0 5.8e-16 58.6 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain HsbA PF12296.3 ETS80021.1 - 2.1e-07 30.7 7.9 2.1e-07 30.7 5.5 3.5 2 2 3 5 5 5 1 Hydrophobic surface binding protein A Spore_YunB PF09560.5 ETS80021.1 - 0.072 12.8 0.9 5.4 6.8 0.0 3.0 3 0 0 3 3 3 0 Sporulation protein YunB (Spo_YunB) NPV_P10 PF05531.7 ETS80021.1 - 0.18 12.0 1.9 0.72 10.1 1.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ROS_MUCR PF05443.6 ETS80021.1 - 0.24 11.1 4.1 1.1 8.9 0.3 2.6 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Toxin_30 PF08117.6 ETS80022.1 - 1.1 9.3 12.0 1 9.4 0.6 3.3 3 0 0 3 3 3 0 Ptu family Kdo PF06293.9 ETS80024.1 - 0.013 14.6 0.7 0.026 13.5 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynactin_p22 PF07426.6 ETS80024.1 - 0.042 13.1 0.6 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 MIP PF00230.15 ETS80025.1 - 9.6e-42 142.9 7.4 1.2e-41 142.6 5.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans_2 PF11951.3 ETS80026.1 - 3.1e-22 78.7 1.2 4.2e-22 78.2 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80026.1 - 0.0018 18.1 13.2 0.0047 16.8 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 ETS80027.1 - 6.8e-10 38.8 10.3 2.7e-09 36.8 7.1 1.8 1 1 0 1 1 1 1 RTA1 like protein adh_short PF00106.20 ETS80029.1 - 2.3e-11 43.9 0.1 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS80029.1 - 2e-07 30.8 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS80029.1 - 0.067 13.1 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 ETS80029.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 ETS80029.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 ETS80031.1 - 2.9e-35 121.6 0.0 2e-20 72.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 ETS80032.1 - 7.8e-16 58.4 0.0 2.1e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS80032.1 - 4.5e-07 29.7 0.0 8.8e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS80032.1 - 0.0032 16.9 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS80032.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS80032.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS80032.1 - 0.11 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ferric_reduct PF01794.14 ETS80033.1 - 5.9e-18 65.1 13.9 5.9e-18 65.1 9.6 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Pec_lyase_C PF00544.14 ETS80033.1 - 8.3e-17 61.3 1.8 1.5e-16 60.4 1.3 1.4 1 0 0 1 1 1 1 Pectate lyase NAD_binding_6 PF08030.7 ETS80033.1 - 4.3e-15 55.9 0.0 7.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS80033.1 - 1.4e-11 44.1 0.0 3.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Beta_helix PF13229.1 ETS80033.1 - 0.44 10.2 19.1 0.33 10.7 9.9 2.5 2 1 1 3 3 3 0 Right handed beta helix region NPV_P10 PF05531.7 ETS80034.1 - 1.3 9.2 5.6 1.9 8.8 1.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA PF00004.24 ETS80035.1 - 1.7e-19 70.3 0.0 2.3e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS80035.1 - 4.1e-06 26.5 0.0 0.083 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS80035.1 - 0.00064 20.5 0.3 0.88 10.4 0.0 4.4 5 0 0 5 5 5 1 AAA domain ArgK PF03308.11 ETS80035.1 - 0.0019 17.0 0.2 0.56 8.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 ETS80035.1 - 0.002 18.1 0.3 0.08 12.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS80035.1 - 0.0075 16.4 2.8 0.63 10.1 0.3 3.6 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS80035.1 - 0.015 15.6 1.2 1.4 9.2 0.1 3.5 3 1 0 3 3 3 0 AAA domain CPT PF07931.7 ETS80035.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 ETS80035.1 - 0.18 11.6 4.1 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF1275 PF06912.6 ETS80036.1 - 8.7e-44 149.2 16.1 1.1e-43 148.9 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2069 PF09842.4 ETS80036.1 - 1.2 9.0 4.9 0.22 11.5 0.1 2.2 2 2 0 2 2 2 0 Predicted membrane protein (DUF2069) 7TMR-DISM_7TM PF07695.6 ETS80036.1 - 2.9 7.5 10.9 6.1 6.4 0.9 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling Lactamase_B PF00753.22 ETS80037.1 - 1.8e-21 76.7 2.9 3.8e-21 75.6 1.8 1.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS80037.1 - 0.00027 20.5 0.2 0.00032 20.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 ETS80038.1 - 5.8e-07 29.5 0.0 2.4e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS80038.1 - 0.00011 22.0 0.1 0.0034 17.1 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 ETS80038.1 - 0.00021 20.3 0.5 0.00084 18.3 0.4 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS80038.1 - 0.014 15.4 0.1 0.13 12.3 0.1 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS80038.1 - 0.032 14.2 0.1 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS80038.1 - 0.069 11.7 0.4 0.1 11.2 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS80038.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.10 ETS80038.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain zf-RING_2 PF13639.1 ETS80039.1 - 1.1e-11 44.2 3.3 2e-11 43.5 2.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS80039.1 - 4.9e-11 42.5 0.7 9.2e-11 41.6 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 ETS80039.1 - 1.3e-06 27.9 1.1 2.5e-06 27.0 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS80039.1 - 5.4e-06 25.9 4.4 2.4e-05 23.9 3.2 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS80039.1 - 3.2e-05 23.8 2.3 0.0001 22.2 1.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS80039.1 - 4e-05 23.1 1.9 7e-05 22.3 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS80039.1 - 0.0015 18.2 2.3 0.0033 17.1 1.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS80039.1 - 0.0026 17.5 2.1 0.0066 16.2 1.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger LEDGF PF11467.3 ETS80039.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) zf-C3HC4_4 PF15227.1 ETS80039.1 - 0.17 11.7 1.0 0.36 10.7 0.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SOG2 PF10428.4 ETS80039.1 - 0.73 8.4 7.4 1.3 7.6 5.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_4 PF14570.1 ETS80039.1 - 2.5 7.7 3.8 0.97 9.0 0.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CMD PF02627.15 ETS80040.1 - 0.00022 21.0 0.1 0.0016 18.2 0.0 2.2 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family zf-C2H2 PF00096.21 ETS80041.1 - 0.00011 22.3 19.6 0.49 10.8 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS80041.1 - 0.00012 22.1 15.6 0.12 12.7 0.0 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS80041.1 - 0.0024 17.6 0.7 0.17 11.8 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2415 PF10313.4 ETS80041.1 - 0.064 12.9 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) zf-met PF12874.2 ETS80041.1 - 0.091 12.9 1.8 2 8.7 0.5 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Secretin_N_2 PF07655.8 ETS80041.1 - 0.6 10.5 0.0 0.6 10.5 0.0 2.8 3 0 0 3 3 3 0 Secretin N-terminal domain IBR PF01485.16 ETS80041.1 - 9.4 6.1 10.3 6.5 6.7 0.2 2.8 1 1 1 2 2 2 0 IBR domain Methyltransf_16 PF10294.4 ETS80042.1 - 3e-10 39.8 0.0 5.4e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 ETS80042.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_8 PF01501.15 ETS80043.1 - 2e-33 115.7 0.0 3.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 ETS80043.1 - 0.00098 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Cation_efflux PF01545.16 ETS80044.1 - 3e-31 108.5 5.2 3.6e-31 108.3 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4231 PF14015.1 ETS80044.1 - 0.76 9.7 3.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Glyco_hydro_47 PF01532.15 ETS80045.1 - 4e-164 546.5 0.0 4.6e-164 546.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EF-hand_1 PF00036.27 ETS80046.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS80046.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 ETS80046.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 ETS80046.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 ETS80046.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETS80046.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETS80046.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETS80046.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 ETS80046.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 ETS80046.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 ETS80046.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 ETS80046.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 ETS80046.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 ETS80046.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 ETS80046.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 ETS80046.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 ETS80046.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 ETS80046.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 ETS80046.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 ETS80047.1 - 9.1e-19 66.9 2.6 9.1e-19 66.9 1.8 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 ETS80047.1 - 2.1e-13 50.3 5.8 1.2e-12 47.9 0.7 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 ETS80047.1 - 0.00068 19.2 6.5 0.11 11.9 0.4 2.7 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 ETS80047.1 - 0.16 11.5 10.5 5.4 6.5 0.9 3.2 3 0 0 3 3 3 0 IncA protein YlbD_coat PF14071.1 ETS80047.1 - 0.37 10.8 5.3 0.08 13.0 0.5 1.9 2 0 0 2 2 2 0 Putative coat protein AAA_13 PF13166.1 ETS80047.1 - 0.63 8.4 6.5 1.2 7.5 4.5 1.4 1 1 0 1 1 1 0 AAA domain SlyX PF04102.7 ETS80047.1 - 1.3 9.4 9.8 6.3 7.2 0.3 3.8 2 2 2 4 4 4 0 SlyX DNA_repr_REX1B PF14966.1 ETS80047.1 - 1.6 9.1 8.0 0.18 12.2 0.7 2.8 3 1 0 3 3 3 0 DNA repair REX1-B Syntaxin_2 PF14523.1 ETS80047.1 - 1.8 8.6 9.3 0.39 10.7 1.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein PAT1 PF09770.4 ETS80049.1 - 0.23 9.6 18.7 0.3 9.2 12.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 ETS80050.1 - 3.2e-31 108.3 18.8 3.2e-31 108.3 13.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Kei1 PF08552.6 ETS80050.1 - 0.079 12.6 2.3 0.43 10.2 0.1 2.4 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Arylsulfotran_2 PF14269.1 ETS80051.1 - 1.2e-65 221.6 4.4 2e-65 220.9 3.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS80051.1 - 3e-18 65.6 0.7 1.8e-17 63.0 0.5 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 ETS80052.1 - 5.3e-09 35.2 36.2 7.6e-09 34.7 10.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS80053.1 - 1.8e-15 56.5 1.4 4.8e-15 55.1 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80053.1 - 7.1e-07 29.0 13.2 1.4e-06 28.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 ETS80055.1 - 2.9e-10 39.7 0.1 4.8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 ETS80056.1 - 3.1e-34 119.0 9.2 4.6e-34 118.5 6.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HATPase_c PF02518.21 ETS80058.1 - 0.0067 16.1 0.0 0.0074 15.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BOFC_N PF08977.5 ETS80058.1 - 0.25 11.2 1.5 0.46 10.3 1.0 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal DUF1816 PF08846.5 ETS80059.1 - 0.12 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) Hydantoinase_B PF02538.9 ETS80060.1 - 2.5e-180 600.1 0.0 3.3e-180 599.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS80060.1 - 6.4e-90 301.1 1.0 1.3e-88 296.8 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS80060.1 - 3.7e-54 182.8 0.3 2.1e-52 177.1 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 ETS80061.1 - 3.7e-33 114.7 28.2 5.5e-33 114.1 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.23 ETS80062.1 - 6.2e-05 22.5 0.0 0.00026 20.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Aminotran_1_2 PF00155.16 ETS80063.1 - 7.3e-19 67.9 0.0 1.6e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS80063.1 - 0.00086 17.9 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ICL PF00463.16 ETS80064.1 - 2.9e-121 405.2 0.5 3.7e-121 404.9 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS80064.1 - 5.5e-08 32.3 0.0 1.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4315 PF14193.1 ETS80064.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Fungal_trans PF04082.13 ETS80065.1 - 1.3e-13 50.4 4.6 2.7e-13 49.4 3.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80065.1 - 4.9e-07 29.5 12.8 9.6e-07 28.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 ETS80066.1 - 5.7e-58 196.9 0.0 7.4e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS80066.1 - 2.1e-08 34.0 0.1 6.7e-08 32.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80066.1 - 5.6e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS80066.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS80066.1 - 0.0061 15.2 0.4 2.1 6.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 ETS80066.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS80067.1 - 2.6e-28 99.4 1.1 3.4e-28 99.0 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS80067.1 - 1.4e-15 57.5 0.3 9.9e-13 48.1 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80067.1 - 6.3e-10 38.9 0.3 2.3e-08 33.9 0.2 3.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS80067.1 - 0.00091 19.0 0.8 0.0018 18.1 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Acyl_transf_2 PF02273.10 ETS80067.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Abhydrolase_4 PF08386.5 ETS80067.1 - 0.018 14.9 0.0 0.19 11.6 0.0 2.4 3 0 0 3 3 3 0 TAP-like protein GTP_EFTU PF00009.22 ETS80067.1 - 0.096 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain adh_short PF00106.20 ETS80068.1 - 6.1e-16 58.7 0.0 1.3e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS80068.1 - 1.5e-09 38.0 0.0 2.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS80068.1 - 8.7e-06 25.5 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS80068.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HgmA PF04209.8 ETS80069.1 - 4.3e-153 509.6 0.0 4.9e-153 509.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.23 ETS80070.1 - 6.1e-53 180.3 0.0 6.1e-45 153.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS80070.1 - 0.0031 17.1 0.2 0.006 16.1 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.18 ETS80071.1 - 4.1e-18 65.2 0.1 5.8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 ETS80072.1 - 3.3e-69 233.6 0.0 5.6e-69 232.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Seadorna_VP6 PF07407.6 ETS80072.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Dioxygenase_C PF00775.16 ETS80073.1 - 4.3e-12 45.6 0.2 7.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase CHD5 PF04420.9 ETS80073.1 - 0.2 11.2 0.5 0.4 10.3 0.4 1.4 1 0 0 1 1 1 0 CHD5-like protein p450 PF00067.17 ETS80074.1 - 1.1e-71 241.7 0.0 1.5e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 ETS80075.1 - 2.5e-20 73.2 0.0 1.1e-12 48.3 0.0 2.1 1 1 1 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 ETS80075.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_11 PF14833.1 ETS80076.1 - 8.6e-25 87.1 0.1 1.6e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 ETS80076.1 - 9.2e-20 71.1 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_2 PF03446.10 ETS80077.1 - 3.7e-39 134.1 0.0 4.8e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS80077.1 - 3.8e-23 81.8 0.0 5.9e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 ETS80077.1 - 7.9e-06 24.8 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 ETS80077.1 - 0.0004 20.7 0.0 0.0007 19.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS80077.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS80077.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 ETS80077.1 - 0.088 12.1 0.1 1 8.6 0.0 2.2 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 ETS80078.1 - 5.8e-59 199.8 0.0 7.6e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 ETS80079.1 - 3.5e-49 167.7 0.0 4.9e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS80079.1 - 6.4e-08 31.8 0.0 0.0027 16.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS80079.1 - 1.1e-05 25.4 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS80079.1 - 1.5e-05 25.1 0.5 5.7e-05 23.2 0.1 2.1 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS80079.1 - 0.00061 18.3 0.0 0.0025 16.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 ETS80079.1 - 0.0064 16.8 0.0 0.37 11.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS80079.1 - 0.0079 15.0 0.0 0.041 12.7 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS80079.1 - 0.0095 15.8 0.0 0.026 14.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS80079.1 - 0.0099 14.9 0.0 0.021 13.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS80079.1 - 0.013 14.4 0.0 0.051 12.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS80079.1 - 0.023 14.4 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS80079.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family YhjQ PF06564.7 ETS80079.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein SE PF08491.5 ETS80079.1 - 0.11 11.3 0.0 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 ETS80079.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS80079.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lactamase_B PF00753.22 ETS80080.1 - 7e-08 32.3 0.0 1.1e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS80080.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS80080.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF4336 PF14234.1 ETS80080.1 - 0.17 11.0 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) Lactamase_B PF00753.22 ETS80081.1 - 2.3e-07 30.6 2.9 7.5e-07 28.9 2.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS80081.1 - 0.0031 17.0 1.1 0.0041 16.6 0.7 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.15 ETS80082.1 - 7.8e-21 73.7 0.1 1.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family zf-C2H2 PF00096.21 ETS80083.1 - 5.3e-08 32.7 16.9 0.00052 20.2 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS80083.1 - 0.00073 19.6 18.7 0.037 14.3 3.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS80083.1 - 0.0098 16.1 8.4 0.0098 16.1 5.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain PyrI_C PF02748.10 ETS80083.1 - 0.024 14.0 6.5 0.29 10.5 0.4 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.10 ETS80083.1 - 0.19 11.5 10.1 3 7.6 2.0 2.7 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 ETS80083.1 - 0.63 10.1 5.8 1.5 8.9 4.0 1.6 1 0 0 1 1 1 0 LIM domain zf-C2H2_jaz PF12171.3 ETS80083.1 - 1.5 9.0 11.4 3.6 7.8 3.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding p450 PF00067.17 ETS80084.1 - 8e-73 245.5 0.0 9.2e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Microtub_assoc PF07989.6 ETS80086.1 - 0.021 14.6 4.9 0.051 13.3 3.4 1.6 1 0 0 1 1 1 0 Microtubule associated Tnp_P_element PF12017.3 ETS80086.1 - 0.13 11.4 3.0 0.24 10.5 2.1 1.4 1 0 0 1 1 1 0 Transposase protein DUF3584 PF12128.3 ETS80086.1 - 0.51 7.6 14.0 0.82 6.9 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4337 PF14235.1 ETS80086.1 - 3.6 7.4 7.0 7.3 6.4 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_18 PF13238.1 ETS80087.1 - 6e-10 39.5 0.0 8.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS80087.1 - 1.4e-05 24.9 0.1 2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETS80087.1 - 3.5e-05 22.9 0.1 5.3e-05 22.3 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 ETS80087.1 - 9.4e-05 23.2 0.0 0.00012 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETS80087.1 - 0.0031 16.7 0.1 0.0053 15.9 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 ETS80087.1 - 0.005 16.5 0.0 0.0083 15.7 0.0 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 ETS80087.1 - 0.0092 15.3 1.2 0.074 12.4 0.0 2.3 2 1 0 2 2 2 1 Thymidylate kinase Med28 PF11594.3 ETS80087.1 - 0.037 14.2 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 AAA_19 PF13245.1 ETS80087.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain MFS_1 PF07690.11 ETS80088.1 - 3.9e-12 45.5 22.4 4.9e-10 38.6 9.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily PD40 PF07676.7 ETS80089.1 - 2.5e-38 129.1 25.2 5.3e-07 29.1 0.7 9.6 9 1 1 10 10 10 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETS80089.1 - 4.2e-13 48.5 0.1 0.0027 16.3 0.0 5.1 5 0 0 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region LysM PF01476.15 ETS80090.1 - 3.4e-07 30.0 0.1 0.0091 15.8 0.0 3.7 4 0 0 4 4 4 2 LysM domain PrmA PF06325.8 ETS80090.1 - 0.25 10.4 0.7 0.32 10.0 0.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) X PF00739.14 ETS80091.1 - 0.45 10.4 2.1 0.49 10.2 1.5 1.2 1 0 0 1 1 1 0 Trans-activation protein X Period_C PF12114.3 ETS80091.1 - 2 7.9 9.1 2.2 7.8 6.3 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Clathrin_lg_ch PF01086.12 ETS80094.1 - 2.3e-73 246.8 6.9 2.6e-73 246.6 4.8 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 ETS80094.1 - 0.27 10.7 1.0 0.56 9.7 0.7 1.5 1 0 0 1 1 1 0 Integrase core domain ATP-synt_B PF00430.13 ETS80094.1 - 1.4 8.7 8.9 2.9 7.7 6.2 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CTD_bind PF04818.8 ETS80095.1 - 2.3e-19 69.4 1.2 7.1e-19 67.8 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 ETS80095.1 - 0.058 13.0 0.9 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 CENP-Q PF13094.1 ETS80095.1 - 0.58 10.1 5.6 3 7.8 3.9 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MRP-L47 PF06984.8 ETS80096.1 - 0.14 12.0 0.8 0.37 10.7 0.3 1.8 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NMO PF03060.10 ETS80097.1 - 2e-70 237.5 1.6 2.4e-70 237.2 1.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETS80097.1 - 6.7e-08 31.8 0.1 0.0055 15.6 0.0 2.8 2 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 ETS80097.1 - 0.069 11.9 8.0 0.042 12.6 3.9 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase SAC3_GANP PF03399.11 ETS80099.1 - 2.2e-31 109.0 0.0 3.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family zf-C2H2 PF00096.21 ETS80100.1 - 3.6e-11 42.7 13.5 0.039 14.2 0.0 6.1 5 1 1 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS80100.1 - 1.1e-08 34.7 18.7 0.027 14.8 0.2 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.2 ETS80100.1 - 5.4e-06 26.4 8.2 0.094 12.9 0.1 5.4 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 ETS80100.1 - 4.5e-05 23.4 10.8 0.018 15.1 1.0 3.1 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 ETS80100.1 - 0.00058 19.6 12.3 3.3 7.7 0.1 5.3 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETS80100.1 - 0.0044 17.0 13.4 5.3 7.2 0.1 4.3 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 ETS80100.1 - 0.014 15.6 16.7 0.075 13.3 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger double domain CK_II_beta PF01214.13 ETS80100.1 - 0.061 12.8 0.5 7 6.1 0.2 2.3 2 0 0 2 2 2 0 Casein kinase II regulatory subunit zf-C2H2_jaz PF12171.3 ETS80100.1 - 0.1 12.7 8.2 1.4 9.1 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 ETS80100.1 - 0.1 12.1 4.2 6 6.5 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS80100.1 - 0.32 10.7 4.7 19 5.0 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 ETS80100.1 - 7.2 6.5 12.1 14 5.6 4.3 3.2 2 1 1 3 3 3 0 IBR domain DUF629 PF04780.7 ETS80100.1 - 7.4 4.9 10.2 4.3 5.7 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF629) IF4E PF01652.13 ETS80101.1 - 8.6e-47 158.7 0.0 1.3e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CAF1A PF12253.3 ETS80102.1 - 1.7e-20 72.9 1.3 1.7e-20 72.9 0.9 2.9 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 ETS80102.1 - 1.9e-05 24.1 33.6 0.00013 21.4 19.1 2.8 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 ETS80102.1 - 0.0022 16.3 16.9 0.0032 15.8 11.7 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein Spore_coat_CotO PF14153.1 ETS80102.1 - 0.0031 16.9 8.3 0.0031 16.9 5.7 1.9 2 0 0 2 2 2 1 Spore coat protein CotO Ycf1 PF05758.7 ETS80102.1 - 0.012 13.3 7.5 0.016 12.9 5.2 1.2 1 0 0 1 1 1 0 Ycf1 Mitofilin PF09731.4 ETS80102.1 - 0.62 8.6 18.3 0.92 8.0 12.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.10 ETS80102.1 - 6.2 5.3 7.0 1.7 7.2 2.8 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HET PF06985.6 ETS80103.1 - 8.5e-31 106.9 0.3 1.5e-30 106.1 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRP1_TIP1 PF00660.12 ETS80103.1 - 0.096 12.5 0.4 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Seripauperin and TIP1 family DUF3433 PF11915.3 ETS80104.1 - 6.2e-31 106.4 22.5 8.7e-23 80.3 2.9 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2235 PF09994.4 ETS80105.1 - 1.1e-42 146.3 0.2 2.8e-42 144.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 ETS80105.1 - 2.6e-05 24.6 0.0 8.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS80105.1 - 0.00067 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETS80105.1 - 0.0079 16.5 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 ETS80105.1 - 0.01 15.0 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS80105.1 - 0.014 14.8 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS80105.1 - 0.027 14.5 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS80105.1 - 0.037 14.8 0.0 0.14 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS80105.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain Peptidase_M48 PF01435.13 ETS80106.1 - 1.4e-51 175.2 0.0 2.1e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 ETS80106.1 - 0.00012 21.1 0.2 0.00031 19.8 0.1 1.7 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 ETS80106.1 - 0.18 10.9 0.8 0.29 10.2 0.2 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain HA2 PF04408.18 ETS80107.1 - 2.4e-19 69.2 0.6 7.9e-19 67.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 ETS80107.1 - 1.8e-15 56.7 0.0 6.1e-15 55.0 0.0 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 ETS80107.1 - 4.6e-14 52.0 0.1 4.1e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS80107.1 - 9.5e-11 41.4 1.8 4.3e-10 39.3 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 ETS80107.1 - 7.6e-09 35.4 0.1 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 ETS80107.1 - 0.00011 22.3 0.3 0.00033 20.7 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 ETS80107.1 - 0.003 17.0 0.2 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 ETS80107.1 - 0.0033 17.2 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 ETS80107.1 - 0.0063 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family KaiC PF06745.8 ETS80107.1 - 0.007 15.4 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 ETS80107.1 - 0.0096 14.8 0.0 0.024 13.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 ETS80107.1 - 0.029 14.1 0.0 0.15 11.8 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 ETS80107.1 - 0.036 14.3 1.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETS80107.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DND1_DSRM PF14709.1 ETS80107.1 - 0.048 13.9 1.0 0.16 12.2 0.7 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Zot PF05707.7 ETS80107.1 - 0.066 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 ETS80107.1 - 0.069 13.4 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DcpS_C PF11969.3 ETS80108.1 - 1.4e-15 57.4 2.3 7.1e-15 55.2 1.6 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 ETS80108.1 - 7.5e-15 55.2 0.1 1.8e-14 54.0 0.1 1.6 1 1 0 1 1 1 1 HIT domain AT_hook PF02178.14 ETS80109.1 - 0.00049 19.4 50.8 0.025 14.2 2.9 6.1 6 1 1 7 7 7 4 AT hook motif TFIIA PF03153.8 ETS80109.1 - 0.0022 17.9 5.6 0.003 17.5 3.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DIOX_N PF14226.1 ETS80110.1 - 4.5e-18 65.8 0.1 9.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS80110.1 - 1.4e-15 57.3 0.0 2.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kinesin PF00225.18 ETS80111.1 - 8.5e-114 379.7 0.0 1.2e-113 379.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF2018 PF09442.5 ETS80111.1 - 0.1 13.1 3.3 0.17 12.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) IncA PF04156.9 ETS80111.1 - 9.3 5.7 9.0 2.8 7.5 4.0 1.7 2 0 0 2 2 2 0 IncA protein Cupin_8 PF13621.1 ETS80112.1 - 6.1e-66 222.4 0.2 7.6e-66 222.1 0.2 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETS80112.1 - 6.1e-07 28.9 0.0 0.00031 20.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 ETS80112.1 - 0.00023 21.4 0.2 0.0068 16.6 0.0 2.9 3 1 0 3 3 3 1 JmjC domain, hydroxylase Sterol-sensing PF12349.3 ETS80113.1 - 2e-35 121.4 8.0 4.2e-35 120.4 5.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 ETS80113.1 - 5.9e-10 37.7 5.4 8.4e-10 37.2 3.8 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 ETS80113.1 - 0.00045 19.9 0.3 0.0017 18.1 0.2 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat CaM_bdg_C0 PF10562.4 ETS80113.1 - 0.85 9.5 3.6 1.7 8.5 2.5 1.4 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF772 PF05598.6 ETS80114.1 - 0.022 14.6 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Transposase domain (DUF772) DUF539 PF04400.8 ETS80114.1 - 0.31 10.5 4.9 0.6 9.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF539) 14-3-3 PF00244.15 ETS80115.1 - 6.5e-08 31.9 0.1 1.5e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 14-3-3 protein Syntaxin-18_N PF10496.4 ETS80116.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FMN_dh PF01070.13 ETS80117.1 - 1.8e-113 379.0 0.0 2.3e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS80117.1 - 3.2e-19 68.4 0.0 6.8e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 ETS80117.1 - 0.00011 21.1 2.9 0.0075 15.1 0.2 3.3 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS80117.1 - 0.00022 20.2 0.3 0.0017 17.3 0.0 2.3 2 1 1 3 3 3 1 Conserved region in glutamate synthase NMO PF03060.10 ETS80117.1 - 0.0004 19.6 0.4 0.0015 17.7 0.2 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 ETS80117.1 - 0.00085 18.4 0.0 0.033 13.2 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Peptidase_M19 PF01244.16 ETS80117.1 - 0.012 14.5 0.0 0.07 12.0 0.0 2.1 2 1 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DHO_dh PF01180.16 ETS80117.1 - 0.019 13.9 0.6 2.8 6.8 0.0 2.4 2 1 0 2 2 2 0 Dihydroorotate dehydrogenase SRP19 PF01922.12 ETS80117.1 - 0.12 13.0 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP19 protein DUF4202 PF13875.1 ETS80118.1 - 2.8e-74 248.7 0.1 3.2e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) SOG2 PF10428.4 ETS80119.1 - 0.0082 14.8 0.7 0.0082 14.8 0.5 1.6 2 0 0 2 2 2 1 RAM signalling pathway protein EphA2_TM PF14575.1 ETS80119.1 - 0.096 13.0 0.0 0.38 11.1 0.0 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 ETS80119.1 - 5.9 5.8 11.0 0.3 10.0 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Med5 PF08689.5 ETS80121.1 - 6.5e-242 805.3 0.0 8.4e-242 804.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SSF PF00474.12 ETS80121.1 - 0.013 14.1 0.1 0.025 13.2 0.1 1.4 1 0 0 1 1 1 0 Sodium:solute symporter family DUF2593 PF10767.4 ETS80121.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) p450 PF00067.17 ETS80122.1 - 2.2e-47 161.6 0.0 2.8e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 ETS80123.1 - 5.5e-29 100.2 0.6 1.3e-28 99.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RskA PF10099.4 ETS80123.1 - 0.14 11.8 5.9 0.44 10.2 0.1 3.0 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF805 PF05656.9 ETS80123.1 - 0.45 10.3 4.3 0.35 10.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF2721 PF11026.3 ETS80123.1 - 3.6 7.2 8.6 0.77 9.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Mito_carr PF00153.22 ETS80124.1 - 1.7e-74 245.5 1.1 7.6e-26 89.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 ETS80124.1 - 1.7e-15 56.8 1.3 6e-06 26.3 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 ETS80124.1 - 9.3e-15 52.7 2.1 1.2e-06 27.4 0.1 5.8 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 ETS80124.1 - 2.6e-14 51.7 2.7 5.2e-06 25.8 0.1 6.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 ETS80124.1 - 1.3e-09 37.5 4.4 0.13 11.8 0.1 5.4 3 2 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 ETS80124.1 - 1.9e-09 36.4 1.3 0.00016 20.8 0.2 4.2 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 ETS80124.1 - 0.016 15.0 0.0 13 5.8 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain Cyclin_N PF00134.18 ETS80125.1 - 3.1e-43 146.3 0.4 7.7e-43 145.0 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS80125.1 - 9.8e-33 112.5 1.7 3.4e-32 110.8 0.2 2.4 3 0 0 3 3 3 1 Cyclin, C-terminal domain Zn_clus PF00172.13 ETS80126.1 - 0.00039 20.2 12.3 0.0007 19.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 ETS80126.1 - 0.02 14.1 0.2 0.16 11.2 0.0 2.5 2 0 0 2 2 2 0 Histone chaperone domain CHZ GATase_4 PF13230.1 ETS80127.1 - 3.1e-17 62.1 0.0 4.5e-15 55.0 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 ETS80127.1 - 8.1e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 ETS80127.1 - 5e-06 25.4 0.0 0.00014 20.7 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Aminotran_1_2 PF00155.16 ETS80128.1 - 4.9e-22 78.3 0.0 6.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS80128.1 - 3.3e-11 42.4 0.0 5.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 ETS80128.1 - 0.0017 17.5 0.0 0.0067 15.6 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase zf-C2H2_4 PF13894.1 ETS80129.1 - 0.0027 17.9 24.6 0.05 13.9 2.9 4.1 3 1 0 3 3 3 3 C2H2-type zinc finger BIR PF00653.16 ETS80129.1 - 0.037 14.4 5.4 0.11 12.9 0.2 2.9 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2 PF00096.21 ETS80129.1 - 2 8.9 21.4 7.7 7.0 0.1 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.2 ETS80129.1 - 9.4 6.6 8.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PQ-loop PF04193.9 ETS80131.1 - 2.5e-24 84.5 18.0 3.4e-14 52.1 1.1 2.6 3 0 0 3 3 3 2 PQ loop repeat MFS_1 PF07690.11 ETS80132.1 - 2.3e-37 128.5 25.2 3e-37 128.1 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 ETS80133.1 - 1.6e-07 31.1 1.5 7.3e-06 25.7 1.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS80133.1 - 6.5e-05 22.9 5.4 0.00045 20.1 3.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80133.1 - 0.00029 20.6 0.1 0.00048 19.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SKG6 PF08693.5 ETS80134.1 - 0.13 11.6 0.2 0.32 10.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3989 PF13150.1 ETS80135.1 - 0.073 12.5 2.1 0.21 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) RNA_pol_Rpc4 PF05132.9 ETS80136.1 - 2.7e-22 79.1 0.0 2.7e-22 79.1 0.0 3.3 3 1 0 3 3 3 1 RNA polymerase III RPC4 UreD PF01774.12 ETS80137.1 - 5.2e-55 186.1 0.0 6.8e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 ETS80138.1 - 1e-25 89.7 0.1 2.8e-25 88.2 0.1 1.8 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 ETS80138.1 - 7e-06 26.2 2.5 6.7e-05 23.0 0.1 3.4 3 1 0 3 3 3 1 HEAT repeats DUF3431 PF11913.3 ETS80139.1 - 2.2e-60 203.8 0.8 3.6e-60 203.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) POT1 PF02765.12 ETS80140.1 - 0.00045 20.1 0.0 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 ETS80140.1 - 0.007 16.2 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Rtf2 PF04641.7 ETS80140.1 - 7.6 5.6 9.7 1.9 7.6 2.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Arm PF00514.18 ETS80141.1 - 3e-95 309.1 15.1 1.1e-13 50.3 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS80141.1 - 1.5e-31 108.4 0.1 5.8e-10 39.3 0.0 5.9 1 1 5 7 7 7 7 HEAT repeats IBB PF01749.15 ETS80141.1 - 2.3e-22 78.9 1.1 3.9e-22 78.2 0.7 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 ETS80141.1 - 3e-22 78.4 10.5 3.4e-09 36.9 0.0 6.2 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 ETS80141.1 - 4.2e-21 73.0 2.0 3.7e-06 26.5 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 ETS80141.1 - 4.8e-10 38.9 0.0 0.0087 15.1 0.0 4.3 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 ETS80141.1 - 1.7e-05 23.3 0.0 0.0054 15.1 0.0 3.0 1 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.11 ETS80141.1 - 0.00061 20.0 0.2 1.6 9.4 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 ETS80141.1 - 0.00076 19.3 0.0 0.99 9.3 0.0 4.3 2 1 4 6 6 6 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 ETS80141.1 - 0.0055 15.0 0.5 0.36 9.0 0.1 3.0 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 ETS80141.1 - 0.071 12.6 0.0 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Cu_amine_oxid PF01179.15 ETS80142.1 - 2.7e-113 378.8 3.9 3.5e-113 378.4 2.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 ETS80142.1 - 1.4e-30 104.9 0.2 3.1e-30 103.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 ETS80142.1 - 1.9e-06 27.8 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.17 ETS80144.1 - 3.9e-48 164.1 0.0 5.3e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 ETS80145.1 - 2.6e-06 26.6 0.2 7e-06 25.2 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.6 ETS80145.1 - 0.0004 20.1 3.0 0.00086 19.0 2.1 1.5 1 0 0 1 1 1 1 CFEM domain FixQ PF05545.6 ETS80145.1 - 0.044 13.4 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Rifin_STEVOR PF02009.11 ETS80145.1 - 0.066 12.8 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2530 PF10745.4 ETS80145.1 - 0.27 11.2 2.5 1.7 8.6 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Med3 PF11593.3 ETS80145.1 - 1.6 7.8 14.3 2.4 7.3 9.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TRAP_alpha PF03896.11 ETS80146.1 - 1.3e-08 34.2 0.0 2.8e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit YscW PF09619.5 ETS80146.1 - 0.0065 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) FAA_hydrolase PF01557.13 ETS80147.1 - 2.7e-49 167.5 0.0 3.8e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETS80147.1 - 2.7e-10 40.1 0.0 5.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PepX_C PF08530.5 ETS80148.1 - 2.8e-42 145.0 0.4 7.3e-42 143.7 0.3 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 ETS80148.1 - 2e-38 132.3 0.0 2.9e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 ETS80148.1 - 0.00019 21.1 0.0 0.00046 19.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS80148.1 - 0.00091 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS80148.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Aldedh PF00171.17 ETS80150.1 - 7.3e-11 41.0 0.6 5.5e-09 34.8 0.4 2.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LigB PF02900.13 ETS80151.1 - 1.6e-20 73.2 0.4 1.6e-19 69.9 0.1 1.9 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_6 PF12697.2 ETS80152.1 - 4.5e-12 46.3 0.2 1.7e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80152.1 - 1.8e-11 44.0 0.0 3.5e-10 39.7 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS80152.1 - 5.4e-06 26.1 0.0 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS80152.1 - 5.1e-05 22.5 0.1 0.0051 16.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 ETS80152.1 - 0.016 13.7 0.0 0.33 9.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 ETS80152.1 - 0.073 12.6 0.1 0.7 9.4 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_M20 PF01546.23 ETS80154.1 - 5e-22 78.3 0.0 7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS80154.1 - 7.9e-21 73.8 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS80154.1 - 0.0022 17.7 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 ATG22 PF11700.3 ETS80155.1 - 4.9e-06 25.2 8.5 6.7e-06 24.8 5.9 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like GMC_oxred_N PF00732.14 ETS80156.1 - 5e-48 163.7 0.0 7.9e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS80156.1 - 9.5e-37 126.4 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS80156.1 - 2.5e-07 29.8 0.5 0.00071 18.5 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS80156.1 - 8.1e-06 24.9 3.1 7.2e-05 21.8 1.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS80156.1 - 0.0022 17.9 2.4 0.0066 16.4 1.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS80156.1 - 0.0034 17.2 0.7 0.0063 16.4 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS80156.1 - 0.009 16.0 1.7 2.7 8.0 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS80156.1 - 0.017 14.2 0.6 0.039 13.0 0.4 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 ETS80156.1 - 0.035 13.0 0.2 0.056 12.3 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SpvD PF05563.7 ETS80156.1 - 0.11 11.9 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Salmonella plasmid virulence protein SpvD 3HCDH_N PF02737.13 ETS80156.1 - 0.28 10.8 0.9 0.61 9.7 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 ETS80156.1 - 0.33 9.7 4.7 0.5 9.1 0.9 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Glyco_tranf_2_3 PF13641.1 ETS80157.1 - 3.1e-12 46.7 0.0 6.1e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS80157.1 - 2.6e-10 39.8 0.2 0.00047 19.4 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 ETS80157.1 - 0.0014 18.3 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 tRNA_int_endo PF01974.12 ETS80158.1 - 9.9e-19 66.9 0.0 2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 ETS80158.1 - 8.1e-08 31.7 0.1 0.00027 20.4 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF2635 PF10948.3 ETS80158.1 - 0.19 11.0 1.7 2.7 7.3 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2635) MFS_1 PF07690.11 ETS80159.1 - 5.2e-28 97.7 38.1 5.2e-28 97.7 26.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS80159.1 - 7.1e-10 38.0 23.4 3.4e-09 35.7 16.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Na_K-ATPase PF00287.13 ETS80159.1 - 0.22 10.2 0.0 0.68 8.6 0.0 1.7 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain Peptidase_S8 PF00082.17 ETS80160.1 - 5.2e-26 91.4 0.5 7.2e-26 90.9 0.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 ETS80160.1 - 0.0016 18.9 0.0 0.045 14.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase inhibitor I9 Nucleoplasmin PF03066.10 ETS80160.1 - 0.021 14.3 0.9 0.032 13.7 0.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 ETS80160.1 - 0.57 9.7 2.8 0.89 9.1 2.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Spt5_N PF11942.3 ETS80160.1 - 1.4 9.5 10.1 2.7 8.6 7.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal HET PF06985.6 ETS80163.1 - 5.8e-28 97.7 2.5 5.8e-28 97.7 1.7 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Adap_comp_sub PF00928.16 ETS80164.1 - 6.7e-91 304.0 0.0 9.1e-91 303.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS80164.1 - 9.6e-09 35.0 0.2 1.6e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 ETS80164.1 - 0.14 11.3 0.0 0.79 8.8 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.5 ETS80165.1 - 5.1e-87 292.5 0.2 6.2e-52 176.9 3.5 3.4 1 1 2 3 3 3 3 Transcription factor Opi1 Lipase_GDSL_2 PF13472.1 ETS80166.1 - 1.3e-14 54.7 5.5 1.9e-14 54.1 3.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS80166.1 - 5.2e-10 39.5 2.8 6.6e-10 39.2 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1212 PF06738.7 ETS80167.1 - 3.6e-33 114.6 13.1 8.8e-33 113.3 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 ETS80167.1 - 2.6e-18 66.2 9.3 2.6e-18 66.2 6.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DnaJ PF00226.26 ETS80169.1 - 4.8e-22 77.4 1.8 1.6e-21 75.7 1.3 2.0 1 0 0 1 1 1 1 DnaJ domain Med9 PF07544.8 ETS80169.1 - 0.0099 15.5 4.4 1.2 8.8 0.2 3.6 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 DUF3735 PF12537.3 ETS80169.1 - 0.5 10.4 0.0 0.5 10.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) Borrelia_P83 PF05262.6 ETS80169.1 - 0.5 8.5 14.0 0.12 10.5 6.6 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein HR1 PF02185.11 ETS80169.1 - 9 6.1 21.1 0.078 12.7 1.1 3.9 4 1 0 4 4 4 0 Hr1 repeat Glyco_hydro_16 PF00722.16 ETS80171.1 - 2.1e-08 33.6 1.3 4.3e-08 32.6 0.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 ETS80171.1 - 0.0039 17.4 2.1 0.0039 17.4 1.5 1.9 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily p450 PF00067.17 ETS80172.1 - 5.6e-57 193.2 0.0 7.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TP6A_N PF04406.9 ETS80173.1 - 8.5e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 ETS80173.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Prenyltrans PF00432.16 ETS80174.1 - 2e-26 91.2 3.7 2.5e-10 39.7 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS80174.1 - 1.1e-24 86.9 1.9 1.7e-13 50.9 0.0 5.3 4 1 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS80174.1 - 1.9e-21 76.0 0.1 2.8e-10 40.1 0.0 6.1 4 2 1 6 6 6 3 Prenyltransferase-like Pec_lyase PF09492.5 ETS80174.1 - 6e-07 28.9 1.7 0.086 12.0 0.0 4.5 2 1 1 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 ETS80174.1 - 0.00045 19.5 0.0 0.0031 16.7 0.0 2.3 2 1 0 2 2 2 1 A-macroglobulin complement component Chromadorea_ALT PF05535.7 ETS80174.1 - 0.0033 17.4 0.1 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Chromadorea ALT protein SGS PF05002.10 ETS80175.1 - 6.7e-26 89.8 5.4 6.7e-26 89.8 3.8 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.11 ETS80175.1 - 1.3e-12 48.0 0.9 2.5e-12 47.1 0.7 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 ETS80175.1 - 5.5e-07 29.1 1.3 3.1e-06 26.7 0.3 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 ETS80175.1 - 2.5e-06 26.9 2.4 0.2 11.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80175.1 - 0.00066 20.2 4.5 0.022 15.4 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat DEDD_Tnp_IS110 PF01548.12 ETS80175.1 - 0.021 14.4 0.1 0.97 9.0 0.0 2.3 2 0 0 2 2 2 0 Transposase TPR_1 PF00515.23 ETS80175.1 - 0.072 12.7 3.8 19 5.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS80175.1 - 0.23 11.3 3.4 1.5 8.8 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank PF00023.25 ETS80176.1 - 7.2e-20 69.7 5.7 5.8e-11 41.6 0.3 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS80176.1 - 2.1e-18 66.2 5.0 9.1e-12 45.1 0.3 2.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS80176.1 - 5e-17 62.0 2.6 4.9e-12 46.0 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS80176.1 - 8.9e-14 50.2 5.0 3.9e-07 29.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETS80176.1 - 1e-13 51.0 3.0 5.3e-09 36.0 0.4 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1110 PF06533.7 ETS80176.1 - 0.02 14.6 4.2 0.22 11.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) RHH_1 PF01402.16 ETS80176.1 - 0.76 9.7 5.7 0.18 11.7 0.7 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family SOBP PF15279.1 ETS80177.1 - 1 9.6 10.5 1.4 9.2 7.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MFS_1 PF07690.11 ETS80178.1 - 6e-20 71.2 52.6 1.3e-19 70.2 33.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.24 ETS80179.1 - 6.6e-71 238.5 0.0 6.8e-70 235.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS80179.1 - 1e-17 64.5 0.0 3.1e-11 43.2 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 ETS80179.1 - 0.0014 18.9 0.0 0.0048 17.2 0.0 2.0 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.18 ETS80179.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Aminotran_3 PF00202.16 ETS80180.1 - 1.2e-99 333.4 0.0 1.4e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_35 PF01301.14 ETS80181.1 - 1.5e-75 254.4 5.9 2.5e-75 253.7 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 ETS80181.1 - 3.6e-50 168.8 7.5 4.4e-25 88.1 0.0 3.6 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 ETS80181.1 - 5.1e-48 162.8 5.5 9.2e-48 162.0 3.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 ETS80181.1 - 3.3e-23 80.8 0.0 7.4e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 ETS80181.1 - 0.00014 21.2 0.5 0.0021 17.3 0.1 2.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF420 PF04238.7 ETS80182.1 - 0.13 12.2 8.3 0.23 11.4 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF420) TMEM173 PF15009.1 ETS80182.1 - 0.21 10.3 2.1 0.31 9.8 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 DUF3112 PF11309.3 ETS80182.1 - 1 9.1 8.0 1.6 8.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Pox_A14 PF05767.7 ETS80182.1 - 1.3 8.9 6.7 0.35 10.8 0.1 2.3 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 SLAC1 PF03595.12 ETS80182.1 - 1.5 7.4 13.0 0.53 8.8 7.0 1.6 2 0 0 2 2 2 0 Voltage-dependent anion channel TctB PF07331.6 ETS80182.1 - 3.4 7.3 10.1 6.5 6.3 7.0 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family XPC-binding PF09280.6 ETS80183.1 - 1.1e-23 82.4 10.1 1.9e-23 81.7 7.0 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 ETS80183.1 - 5.3e-19 67.3 0.5 8e-19 66.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 ETS80183.1 - 1.1e-13 50.5 6.4 1.8e-08 33.9 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 ETS80183.1 - 1.1e-10 41.0 0.5 2.3e-10 39.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETS80183.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETS80183.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 ETS80183.1 - 0.054 13.1 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 ETS80183.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain TFIIA PF03153.8 ETS80183.1 - 0.31 10.9 4.1 0.38 10.6 2.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NMO PF03060.10 ETS80184.1 - 2.6e-73 247.0 0.8 3.1e-73 246.8 0.6 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETS80184.1 - 4e-10 39.1 0.0 1.1e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 ETS80184.1 - 9.4e-06 24.7 0.3 1.6e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS80184.1 - 0.0001 21.3 0.4 0.00019 20.4 0.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.9 ETS80184.1 - 0.0025 16.7 0.1 0.013 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ECH PF00378.15 ETS80185.1 - 3.9e-37 127.7 0.0 5.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS80185.1 - 0.0049 16.6 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S49 AMP-binding PF00501.23 ETS80186.1 - 1.4e-78 264.2 0.0 1.7e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS80186.1 - 2.5e-12 47.5 0.0 6.8e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 ETS80187.1 - 9e-17 61.0 0.0 1.6e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80187.1 - 2.4e-07 30.0 0.0 4.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETS80188.1 - 7.1e-54 182.6 0.0 9.3e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80188.1 - 8.9e-30 103.6 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80188.1 - 8.9e-07 28.1 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS80188.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS80188.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 ETS80188.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL p450 PF00067.17 ETS80189.1 - 2.4e-50 171.4 0.0 3.3e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS80190.1 - 7.2e-22 78.0 0.0 1.8e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2626 PF11117.3 ETS80191.1 - 9 6.7 8.4 0.87 10.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) Amastin PF07344.6 ETS80193.1 - 2.6 7.6 10.1 0.079 12.5 0.8 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein UPF0220 PF05255.6 ETS80196.1 - 1.2e-64 216.5 2.3 1.4e-64 216.3 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) SMI1_KNR4 PF09346.5 ETS80197.1 - 5.8e-30 103.9 0.0 1.3e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RAP1 PF07218.6 ETS80197.1 - 0.14 10.1 1.2 0.3 9.1 0.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec8_exocyst PF04048.9 ETS80198.1 - 2.2e-48 163.4 0.0 5.9e-48 162.1 0.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 ETS80198.1 - 1e-09 37.7 0.3 1.8e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 ETS80198.1 - 0.064 11.4 0.5 0.11 10.6 0.3 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 His_Phos_2 PF00328.17 ETS80199.1 - 1.2e-23 84.0 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Abhydrolase_2 PF02230.11 ETS80200.1 - 1.7e-12 47.2 0.0 8.6e-10 38.4 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETS80200.1 - 2.7e-05 23.9 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS80200.1 - 4.4e-05 23.4 2.1 0.00083 19.2 1.5 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 ETS80200.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Porin_3 PF01459.17 ETS80201.1 - 9.1e-80 267.8 0.1 1.1e-79 267.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 ETS80202.1 - 1.9e-60 203.6 0.0 2.7e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 ETS80202.1 - 3.1e-19 69.6 0.2 6e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 ETS80202.1 - 0.00034 20.5 0.0 0.0016 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS80202.1 - 0.00089 20.0 0.6 0.4 11.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain KTI12 PF08433.5 ETS80202.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TroA PF01297.12 ETS80202.1 - 0.068 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Periplasmic solute binding protein family UCH_1 PF13423.1 ETS80203.1 - 1.5e-77 260.9 0.2 4.5e-77 259.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 ETS80203.1 - 6.7e-14 51.6 0.0 3.2e-13 49.4 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase COesterase PF00135.23 ETS80204.1 - 7.1e-87 292.3 0.2 7.5e-77 259.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS80204.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80204.1 - 0.0012 18.6 0.3 0.002 17.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS80204.1 - 0.0026 17.6 0.2 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 ETS80205.1 - 7.4e-09 35.3 4.7 1.8e-08 34.1 3.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS80205.1 - 9.1e-06 24.7 0.1 1.9e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 ETS80206.1 - 5.4e-71 239.4 0.0 6.6e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 ETS80206.1 - 0.072 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX RPE65 PF03055.10 ETS80207.1 - 1.2e-99 334.1 0.0 1.4e-99 333.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.8 ETS80208.1 - 1.2e-20 73.9 0.8 4.2e-15 55.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80208.1 - 1.6e-14 53.8 0.0 2.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS80208.1 - 1.2e-10 41.6 0.6 1.7e-10 41.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS80208.1 - 1.9e-08 33.8 0.1 6.5e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 ETS80208.1 - 8e-07 28.4 0.2 0.00058 19.1 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family BAAT_C PF08840.6 ETS80208.1 - 5.5e-05 22.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 ETS80208.1 - 8.8e-05 21.5 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 ETS80208.1 - 0.00051 19.6 0.0 0.0042 16.7 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_2 PF02230.11 ETS80208.1 - 0.0083 15.5 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 ETS80208.1 - 0.014 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 ETS80208.1 - 0.021 14.2 0.2 0.039 13.3 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.15 ETS80208.1 - 0.025 14.1 0.3 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold SBP_bac_5 PF00496.17 ETS80208.1 - 0.04 12.7 0.0 0.076 11.8 0.0 1.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle Abhydrolase_4 PF08386.5 ETS80208.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 1 0 TAP-like protein DUF2974 PF11187.3 ETS80208.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2424 PF10340.4 ETS80208.1 - 0.15 10.6 1.1 0.43 9.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) TPP_enzyme_N PF02776.13 ETS80209.1 - 1.3e-33 115.9 0.1 6.5e-33 113.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 ETS80209.1 - 1.3e-17 63.8 0.0 2.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS80209.1 - 7.7e-17 61.3 0.0 3.9e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_S15 PF02129.13 ETS80210.1 - 1.5e-36 126.2 0.0 3.9e-36 124.8 0.0 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS80210.1 - 5.2e-25 88.6 0.0 7.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Ribosomal_L5_C PF00673.16 ETS80211.1 - 8.5e-21 73.5 0.0 1.6e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 ETS80211.1 - 0.013 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 PilS PF08805.6 ETS80211.1 - 0.13 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 PilS N terminal Fes1 PF08609.5 ETS80212.1 - 3.9e-24 84.9 8.2 1.1e-23 83.5 2.1 2.9 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.18 ETS80212.1 - 0.00023 20.8 0.5 0.019 14.8 0.0 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETS80212.1 - 0.00063 20.1 4.4 0.03 14.8 0.1 3.9 2 1 2 4 4 4 2 HEAT-like repeat HEAT PF02985.17 ETS80212.1 - 0.0049 16.8 0.6 0.18 11.9 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 ETS80212.1 - 0.025 14.8 3.9 1.2 9.4 2.7 3.0 1 1 0 1 1 1 0 HEAT repeats Actin PF00022.14 ETS80213.1 - 9.9e-160 531.2 0.0 1.1e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 ETS80213.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RF-1 PF00472.15 ETS80214.1 - 3e-26 91.4 0.5 3e-26 91.4 0.4 1.7 2 0 0 2 2 2 1 RF-1 domain Fmp27_WPPW PF10359.4 ETS80214.1 - 0.94 7.8 6.9 1.2 7.5 4.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain WD40 PF00400.27 ETS80215.1 - 6.5e-66 216.0 11.4 7.4e-08 31.9 0.0 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Endostatin PF06482.6 ETS80216.1 - 0.089 12.1 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin OTT_1508_deam PF14441.1 ETS80217.1 - 1.4e-12 47.5 0.0 2.1e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 OTT_1508-like deaminase ETAA1 PF15350.1 ETS80217.1 - 0.037 12.0 0.1 0.042 11.8 0.1 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue Pkinase PF00069.20 ETS80218.1 - 7.9e-64 215.2 0.0 9.4e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80218.1 - 9.2e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80218.1 - 9.9e-08 31.2 0.0 5e-07 28.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 ETS80218.1 - 0.0014 18.4 0.1 0.013 15.2 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS80218.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 ETS80218.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 ETS80219.1 - 1.3e-78 262.8 0.0 2.1e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 ETS80219.1 - 2.4e-52 177.6 0.0 3.5e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 ETS80219.1 - 0.017 14.5 0.0 0.099 12.0 0.0 2.2 2 0 0 2 2 2 0 MIF4G domain Ribosomal_L4 PF00573.17 ETS80221.1 - 1.8e-36 125.3 0.5 2.4e-36 124.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 ETS80221.1 - 1.7e-26 91.9 0.8 1.7e-26 91.9 0.6 2.0 3 0 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain Cohesin_load PF10345.4 ETS80222.1 - 4.7e-126 421.4 1.0 6.2e-126 421.0 0.7 1.1 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_6 PF12697.2 ETS80223.1 - 1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS80223.1 - 4.7e-10 39.4 0.0 7.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80223.1 - 0.00011 22.0 0.0 0.00038 20.2 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family RAI1 PF08652.6 ETS80224.1 - 3.3e-27 94.0 1.1 4.1e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease ResIII PF04851.10 ETS80224.1 - 0.015 15.1 0.8 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF410 PF04190.8 ETS80226.1 - 1.9e-49 168.5 0.0 2.3e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VEGF_C PF14554.1 ETS80228.1 - 0.24 11.2 6.1 0.45 10.3 4.2 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain Metal_resist PF13801.1 ETS80228.1 - 0.47 10.4 4.7 1.2 9.0 3.3 1.7 1 1 0 1 1 1 0 Heavy-metal resistance MFS_1 PF07690.11 ETS80229.1 - 2.5e-41 141.5 41.6 2.5e-41 141.5 28.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS80229.1 - 6e-16 58.0 14.1 6e-16 58.0 9.8 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 ETS80229.1 - 9.4e-05 20.7 15.6 0.00015 20.0 10.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MARVEL PF01284.18 ETS80230.1 - 1.3e-05 25.0 13.4 2.2e-05 24.3 9.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 ETS80230.1 - 0.011 15.8 0.8 0.018 15.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) ODV-E18 PF10717.4 ETS80230.1 - 0.72 9.3 2.2 1 8.8 0.1 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CD20 PF04103.10 ETS80230.1 - 2 8.3 5.9 5.6 6.8 4.1 1.7 1 1 0 1 1 1 0 CD20-like family Nop16 PF09420.5 ETS80231.1 - 8.9e-51 172.2 2.3 1.1e-50 171.9 1.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 TerB-N PF13208.1 ETS80231.1 - 0.1 12.0 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 TerB-N Fungal_trans_2 PF11951.3 ETS80232.1 - 2.5e-55 187.6 0.2 4.1e-55 186.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80232.1 - 1.2e-05 25.0 5.6 2.5e-05 24.0 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GSHPx PF00255.14 ETS80233.1 - 1.3e-39 133.9 0.0 1.6e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 ETS80233.1 - 9.4e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) AhpC-TSA PF00578.16 ETS80233.1 - 0.00065 19.3 0.1 0.0014 18.3 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS80233.1 - 0.0075 15.8 0.1 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 Redoxin DAO PF01266.19 ETS80234.1 - 7.6e-52 176.3 6.8 2.1e-51 174.9 4.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS80234.1 - 6.1e-05 22.9 0.6 0.00017 21.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS80234.1 - 7.5e-05 23.0 0.9 0.11 12.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 ETS80234.1 - 0.00021 20.5 0.3 0.014 14.6 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Trp_halogenase PF04820.9 ETS80234.1 - 0.0017 17.0 1.8 0.0053 15.4 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS80234.1 - 0.0041 17.0 0.6 2 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS80234.1 - 0.0087 16.1 0.0 0.97 9.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 ETS80234.1 - 0.052 12.5 0.1 0.052 12.5 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Strep_67kDa_ant PF06100.6 ETS80234.1 - 0.071 11.4 0.5 1.1 7.5 0.1 2.0 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Thi4 PF01946.12 ETS80234.1 - 0.075 12.1 0.2 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DHDPS PF00701.17 ETS80235.1 - 6.7e-36 123.3 0.0 7.8e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 ETS80236.1 - 1.2e-10 41.9 0.0 2.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HrpF PF06266.7 ETS80236.1 - 0.085 12.9 0.1 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 HrpF protein EBP PF05241.7 ETS80237.1 - 2.6e-70 235.3 9.3 3.2e-70 235.1 6.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein Peptidase_C48 PF02902.14 ETS80238.1 - 8.4e-35 120.3 0.0 2.1e-34 119.0 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.13 ETS80239.1 - 9.5e-08 31.8 8.1 1.7e-07 31.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS80240.1 - 5.3e-46 157.0 0.0 7.6e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NEL PF14496.1 ETS80240.1 - 0.0043 16.3 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting DUF1705 PF08019.7 ETS80241.1 - 0.015 14.8 8.3 0.36 10.3 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Cation_ATPase_C PF00689.16 ETS80241.1 - 7.1 6.1 13.3 3.1 7.3 0.7 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Methyltransf_2 PF00891.13 ETS80242.1 - 3.9e-33 114.6 0.0 1.4e-32 112.7 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 ETS80242.1 - 0.003 17.3 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Exc PF07825.6 ETS80242.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Excisionase-like protein HET PF06985.6 ETS80244.1 - 2.6e-22 79.4 5.4 4.1e-21 75.6 3.7 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS80245.1 - 2.7e-21 76.1 9.5 1.7e-18 67.0 2.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Exo_endo_phos PF03372.18 ETS80246.1 - 7.6e-25 88.2 0.4 1.3e-24 87.4 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FBPase_glpX PF03320.8 ETS80246.1 - 0.2 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded adh_short PF00106.20 ETS80247.1 - 6.3e-25 88.0 3.5 8.9e-25 87.5 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS80247.1 - 1e-24 87.6 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS80247.1 - 4e-12 46.1 2.1 6.1e-12 45.5 1.5 1.2 1 0 0 1 1 1 1 KR domain N2227 PF07942.7 ETS80248.1 - 6.1e-101 336.9 0.0 7.8e-101 336.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 ETS80248.1 - 5.8e-07 29.3 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS80248.1 - 0.00024 21.5 0.0 0.0012 19.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80248.1 - 0.021 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80248.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain HTHP PF11534.3 ETS80249.1 - 0.12 12.4 0.0 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) HEAT_2 PF13646.1 ETS80250.1 - 2.7e-29 101.2 2.5 4.1e-09 36.5 0.0 8.4 3 3 6 9 9 9 7 HEAT repeats HEAT_EZ PF13513.1 ETS80250.1 - 4e-28 97.1 17.9 3.7e-13 49.5 0.0 11.4 11 2 3 14 14 14 4 HEAT-like repeat HEAT PF02985.17 ETS80250.1 - 2e-27 92.7 18.7 4.5e-06 26.2 0.0 10.2 12 0 0 12 12 10 5 HEAT repeat Vac14_Fab1_bd PF12755.2 ETS80250.1 - 2.3e-11 43.9 0.0 0.063 13.6 0.0 7.0 5 2 2 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 ETS80250.1 - 7e-11 42.2 1.3 0.17 11.7 0.0 7.2 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 ETS80250.1 - 5.8e-08 31.8 0.3 0.17 10.5 0.0 4.6 4 1 0 4 4 4 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 ETS80250.1 - 4.3e-07 28.6 0.0 0.021 13.1 0.0 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 ETS80250.1 - 9.8e-07 28.3 4.7 0.087 12.6 0.0 7.1 7 1 0 7 7 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 ETS80250.1 - 6.4e-05 22.7 0.0 0.0025 17.7 0.0 3.6 4 1 0 4 4 3 1 Importin-beta N-terminal domain DUF1546 PF07571.8 ETS80250.1 - 0.032 14.3 0.0 24 5.1 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) DUF3437 PF11919.3 ETS80250.1 - 0.032 13.9 0.0 2.6 7.8 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.11 ETS80250.1 - 0.056 13.9 6.9 1.2 9.8 0.0 5.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.7 ETS80250.1 - 0.15 11.7 0.1 8.6 6.0 0.0 3.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Acetyltransf_7 PF13508.1 ETS80251.1 - 1.5e-06 28.2 0.0 1.9e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS80251.1 - 0.0015 18.4 0.2 0.0025 17.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS80251.1 - 0.0025 17.9 0.1 0.24 11.5 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS80251.1 - 0.047 13.4 0.0 0.17 11.6 0.0 2.0 2 1 0 2 2 2 0 FR47-like protein p450 PF00067.17 ETS80252.1 - 4.6e-09 35.3 0.0 5.1e-06 25.2 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 ETS80253.1 - 6.7e-42 143.4 49.1 6.7e-42 143.4 34.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS80253.1 - 5e-12 44.8 23.5 5e-12 44.8 16.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS80253.1 - 5.3e-10 38.4 15.3 5.3e-10 38.4 10.6 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2976 PF11190.3 ETS80253.1 - 0.062 12.8 3.1 2 7.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) CorA PF01544.13 ETS80255.1 - 0.0001 21.4 0.6 0.00015 20.9 0.0 1.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HET PF06985.6 ETS80257.1 - 3.6e-32 111.4 0.0 5.1e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 ETS80258.1 - 3.2e-07 29.5 0.6 7.4e-07 28.3 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MSA_2 PF00985.12 ETS80258.1 - 0.41 10.7 4.6 0.68 10.0 3.2 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Arginase PF00491.16 ETS80259.1 - 7.5e-80 268.1 0.6 8.5e-80 268.0 0.4 1.0 1 0 0 1 1 1 1 Arginase family AMP-binding PF00501.23 ETS80260.1 - 5.2e-106 354.5 0.0 7.7e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 ETS80260.1 - 9.4e-81 271.0 0.2 1.9e-80 270.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS80260.1 - 1.1e-62 210.9 5.9 2.8e-60 203.1 1.5 3.5 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 ETS80260.1 - 2.3e-56 190.3 7.8 1.9e-54 184.0 1.7 3.5 3 0 0 3 3 3 2 short chain dehydrogenase NAD_binding_4 PF07993.7 ETS80260.1 - 4.5e-52 176.4 0.0 2.6e-50 170.7 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.16 ETS80260.1 - 6.4e-52 176.8 0.1 6.5e-42 143.9 0.2 2.3 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 ETS80260.1 - 4e-45 152.5 0.9 1e-44 151.1 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 ETS80260.1 - 5.7e-24 84.1 0.3 8.1e-12 45.2 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 ETS80260.1 - 4.2e-13 49.2 0.0 6.4e-07 29.0 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 ETS80260.1 - 1.3e-12 48.5 0.0 5.2e-12 46.5 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NmrA PF05368.8 ETS80260.1 - 6.5e-06 25.5 0.3 0.12 11.6 0.0 2.7 2 0 0 2 2 2 2 NmrA-like family Thiolase_N PF00108.18 ETS80260.1 - 1.1e-05 24.5 0.1 3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 ETS80260.1 - 0.00013 20.9 0.0 0.39 9.5 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 ETS80260.1 - 0.0007 18.3 0.0 1 8.0 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS80260.1 - 0.001 19.0 2.1 0.022 14.7 0.0 3.6 4 1 0 4 4 4 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS80260.1 - 0.021 13.6 1.8 7.3 5.3 0.2 3.8 3 1 0 3 3 3 0 RmlD substrate binding domain NmrA PF05368.8 ETS80261.1 - 8e-22 77.6 0.0 1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS80261.1 - 6.3e-09 36.0 0.0 1.3e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS80261.1 - 2.6e-06 27.2 0.1 4.4e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS80261.1 - 1.6e-05 24.8 0.1 3.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS80261.1 - 0.00089 18.7 0.0 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS80261.1 - 0.0021 16.7 0.0 0.003 16.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 ETS80261.1 - 0.025 14.9 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 ETS80261.1 - 0.12 12.3 0.1 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PhyH PF05721.8 ETS80262.1 - 1.7e-36 126.2 0.1 2.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS80262.1 - 0.00047 18.7 0.0 0.00082 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) AATase PF07247.7 ETS80263.1 - 1.9e-08 33.2 0.0 4.7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Abhydrolase_3 PF07859.8 ETS80264.1 - 6.7e-25 87.8 0.0 9.2e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS80264.1 - 2.5e-11 42.8 0.0 3.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS80264.1 - 0.002 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS80264.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2973 PF11189.3 ETS80267.1 - 3.2 7.5 4.8 2.1 8.1 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) HET PF06985.6 ETS80268.1 - 3.2e-32 111.5 0.4 6e-32 110.7 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 ETS80269.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Fungal_trans_2 PF11951.3 ETS80270.1 - 1e-08 34.1 0.2 6.1e-08 31.6 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80270.1 - 0.00032 20.5 9.6 0.00059 19.7 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-FPG_IleRS PF06827.9 ETS80270.1 - 9.9 5.9 7.6 12 5.6 0.9 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Dioxygenase_C PF00775.16 ETS80271.1 - 2.1e-09 36.8 1.2 5.9e-09 35.4 0.9 1.7 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.16 ETS80272.1 - 3.4e-09 36.2 0.0 7.7e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase Zn_clus PF00172.13 ETS80273.1 - 2.2e-08 33.8 12.4 3.8e-08 33.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 ETS80274.1 - 2.9e-29 100.8 9.4 8e-11 41.7 0.2 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat Patatin PF01734.17 ETS80274.1 - 7e-17 62.0 0.1 1.6e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_19 PF14559.1 ETS80274.1 - 3.8e-16 59.1 4.8 0.00014 22.1 0.0 5.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETS80274.1 - 3.8e-16 58.4 17.7 0.0059 16.5 0.0 6.8 8 0 0 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 ETS80274.1 - 1.6e-15 57.0 1.8 0.0002 21.4 0.0 4.6 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 ETS80274.1 - 2e-14 52.2 0.7 0.8 9.7 0.0 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80274.1 - 6.8e-14 51.1 10.3 0.21 12.3 0.5 6.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80274.1 - 2.1e-13 48.9 8.3 0.99 9.3 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80274.1 - 2.9e-13 49.2 2.0 0.00024 20.7 0.1 4.4 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 ETS80274.1 - 8e-13 48.6 10.4 3.3e-05 24.4 0.6 5.9 3 1 6 9 9 7 5 Tetratricopeptide repeat NB-ARC PF00931.17 ETS80274.1 - 4.9e-12 45.3 0.0 1.6e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain TPR_20 PF14561.1 ETS80274.1 - 2.9e-11 43.3 9.2 0.012 15.6 0.1 6.4 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80274.1 - 1.3e-10 40.9 0.9 0.11 12.9 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS80274.1 - 1.7e-07 30.8 6.7 0.7 10.2 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80274.1 - 2.6e-07 29.9 0.0 2.7 7.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS80274.1 - 1.7e-06 27.3 0.5 12 5.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 ETS80274.1 - 2.1e-06 27.3 0.1 2.1 8.5 0.0 5.7 5 0 0 5 5 5 1 PPR repeat TPR_4 PF07721.9 ETS80274.1 - 6.6e-05 22.9 1.5 1 9.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 ETS80274.1 - 0.002 18.2 1.7 13 6.3 0.0 5.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain AAA_22 PF13401.1 ETS80274.1 - 0.0028 17.8 0.0 0.016 15.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 ETS80274.1 - 0.021 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain HTH_27 PF13463.1 ETS80274.1 - 0.028 14.7 0.2 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain Clathrin PF00637.15 ETS80274.1 - 0.071 12.7 0.6 0.44 10.1 0.1 2.4 2 1 0 2 2 1 0 Region in Clathrin and VPS GATA PF00320.22 ETS80275.1 - 1.7e-05 24.0 4.4 0.0069 15.7 0.4 2.7 2 0 0 2 2 2 2 GATA zinc finger ECH_C PF13766.1 ETS80276.1 - 6e-34 116.7 0.1 1.2e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 ETS80276.1 - 1.8e-23 82.9 0.0 6.7e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family LSM PF01423.17 ETS80277.1 - 5.5e-18 64.2 0.1 7.2e-18 63.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.12 ETS80278.1 - 8.5e-114 379.4 2.8 1.3e-113 378.9 1.9 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS80278.1 - 7e-43 146.3 0.1 7e-43 146.3 0.1 1.8 2 0 0 2 2 2 1 DAK2 domain IF-2B PF01008.12 ETS80279.1 - 1.1e-52 178.7 0.1 3.1e-52 177.3 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_26 PF13659.1 ETS80279.1 - 0.042 13.8 0.0 12 5.9 0.0 2.9 1 1 1 2 2 2 0 Methyltransferase domain UPF0081 PF03652.10 ETS80280.1 - 0.077 13.1 0.1 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) COMPASS-Shg1 PF05205.7 ETS80281.1 - 4.6e-24 84.7 0.2 1.4e-23 83.2 0.2 1.9 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPRY PF00622.23 ETS80282.1 - 1.3e-17 64.0 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Apc13p PF05839.6 ETS80283.1 - 2.2e-29 101.2 0.0 2.6e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 ETS80284.1 - 5e-35 120.2 0.0 5.9e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.15 ETS80285.1 - 2.1e-41 141.0 0.0 3.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS80285.1 - 4.8e-09 36.2 0.3 1.6e-08 34.5 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 ETS80285.1 - 0.00056 19.8 0.0 0.00085 19.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 ETS80286.1 - 2.1e-61 207.6 0.0 3.2e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 ETS80286.1 - 1.3e-42 145.4 0.0 1.9e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B KfrA_N PF11740.3 ETS80286.1 - 0.024 15.0 0.1 0.073 13.5 0.1 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Prp19_bind PF06991.6 ETS80287.1 - 1.7e-49 168.5 22.3 1.7e-49 168.5 15.5 2.3 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain UCH PF00443.24 ETS80288.1 - 5.1e-40 137.2 0.5 7.9e-40 136.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 ETS80288.1 - 4.2 7.3 5.6 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Cytochrom_B562 PF07361.6 ETS80288.1 - 4.6 7.7 6.5 0.49 10.8 0.9 2.1 2 0 0 2 2 2 0 Cytochrome b562 Alb1 PF09135.6 ETS80289.1 - 5.9e-20 71.9 16.6 5.9e-20 71.9 11.5 1.5 2 0 0 2 2 2 1 Alb1 RNase_E_G PF10150.4 ETS80289.1 - 0.028 13.6 4.5 0.035 13.3 3.1 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Z1 PF10593.4 ETS80289.1 - 0.19 10.9 2.3 0.23 10.6 1.6 1.1 1 0 0 1 1 1 0 Z1 domain Peptidase_S64 PF08192.6 ETS80289.1 - 0.72 8.1 9.2 0.85 7.8 6.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 V_ATPase_I PF01496.14 ETS80289.1 - 2.4 5.9 4.1 2.6 5.7 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 ETS80289.1 - 3.1 7.5 11.7 5.5 6.7 8.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DNA_pol_viral_N PF00242.12 ETS80289.1 - 6.5 5.6 9.1 7.8 5.4 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Kin17_mid PF10357.4 ETS80290.1 - 2.8e-52 175.6 1.7 2.8e-52 175.6 1.2 2.3 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 ETS80290.1 - 1.3e-05 25.1 2.4 2.6e-05 24.1 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS80290.1 - 2.3e-05 24.4 3.2 4.1e-05 23.6 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS80290.1 - 0.0082 16.2 0.8 0.0082 16.2 0.6 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_7 PF03492.10 ETS80290.1 - 0.056 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ecl1 PF12855.2 ETS80290.1 - 0.088 12.1 0.2 0.2 10.9 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Menin PF05053.8 ETS80290.1 - 0.28 9.2 7.5 0.35 8.9 5.2 1.2 1 0 0 1 1 1 0 Menin Phage_min_cap2 PF06152.6 ETS80290.1 - 1.7 7.5 13.4 3.2 6.6 6.5 2.1 1 1 1 2 2 2 0 Phage minor capsid protein 2 CTD_bind PF04818.8 ETS80294.1 - 3.4e-07 30.3 0.0 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PAT1 PF09770.4 ETS80294.1 - 0.58 8.3 10.6 0.91 7.6 7.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tau95 PF09734.4 ETS80295.1 - 5.3e-62 209.9 0.0 6.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Ribos_L4_asso_C PF14374.1 ETS80295.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain B56 PF01603.15 ETS80296.1 - 3e-174 579.4 4.8 3.6e-174 579.1 3.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4243 PF14027.1 ETS80297.1 - 4.4e-79 266.2 3.6 5.7e-79 265.9 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3631 PF12307.3 ETS80297.1 - 0.041 13.8 1.9 0.046 13.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) XG_FTase PF03254.8 ETS80297.1 - 0.13 10.6 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Kelch_5 PF13854.1 ETS80298.1 - 1.1e-07 31.6 0.1 1.1e-07 31.6 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 ETS80298.1 - 1.4e-06 28.2 9.3 0.006 16.7 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS80298.1 - 0.22 11.7 5.9 9.7 6.5 0.0 4.8 4 1 0 4 4 4 0 Kelch motif Adeno_E3_CR2 PF02439.10 ETS80298.1 - 0.23 11.0 1.0 0.4 10.2 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_1 PF01344.20 ETS80298.1 - 1.2 8.7 11.0 12 5.4 0.1 5.0 5 0 0 5 5 5 0 Kelch motif ubiquitin PF00240.18 ETS80299.1 - 4.3e-06 26.0 0.1 1.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 ETS80299.1 - 1.3e-05 25.2 0.1 4.1e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 ETS80299.1 - 0.033 14.0 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 ETS80300.1 - 1.4e-82 275.8 0.0 2.2e-81 271.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Asparaginase PF00710.15 ETS80301.1 - 3.9e-103 344.5 0.0 1.2e-102 343.0 0.0 1.7 2 0 0 2 2 2 1 Asparaginase Ank_2 PF12796.2 ETS80301.1 - 6.2e-13 48.8 0.4 1.2e-12 47.9 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS80301.1 - 3.8e-10 39.9 0.4 0.00017 21.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS80301.1 - 4.7e-10 38.7 0.2 0.00071 19.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS80301.1 - 3e-07 30.4 0.4 4e-05 23.7 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80301.1 - 6.4e-06 25.9 0.1 0.78 10.1 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat AMP-binding PF00501.23 ETS80303.1 - 6.8e-28 97.2 0.0 2.4e-25 88.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme Glyco_hydro_43 PF04616.9 ETS80304.1 - 4.6e-40 137.4 5.5 7e-40 136.8 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 NAP PF00956.13 ETS80305.1 - 1.6e-44 151.9 6.9 1.6e-44 151.9 4.8 1.7 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.7 ETS80305.1 - 7.5 4.3 18.9 11 3.8 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_76 PF03663.9 ETS80306.1 - 6.7e-156 519.3 13.3 8e-156 519.0 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS80306.1 - 0.012 14.7 5.8 0.43 9.5 0.1 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 IF3_C PF00707.17 ETS80307.1 - 1.1e-12 47.5 0.1 2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 ETS80307.1 - 3.6e-06 26.4 0.4 8.7e-06 25.2 0.4 1.5 2 0 0 2 2 2 1 Mitochondrial translation initiation factor ATP-synt_S1 PF05827.7 ETS80307.1 - 0.036 13.3 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Ligase_CoA PF00549.14 ETS80307.1 - 0.052 13.1 0.1 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 CoA-ligase Dala_Dala_lig_N PF01820.16 ETS80307.1 - 0.3 11.4 1.5 1.6 9.0 1.1 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Peptidase_S24 PF00717.18 ETS80308.1 - 7e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 ETS80308.1 - 0.0043 16.5 0.0 0.044 13.3 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Arm PF00514.18 ETS80309.1 - 5.7e-71 232.1 32.3 1.5e-13 50.0 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 ETS80309.1 - 2.9e-23 81.9 13.6 3.3e-07 30.4 0.4 7.5 2 2 2 5 5 5 5 HEAT repeats HEAT PF02985.17 ETS80309.1 - 2.9e-19 67.3 16.6 0.016 15.2 0.0 9.5 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 ETS80309.1 - 1e-15 57.6 14.7 0.0023 18.3 0.2 8.4 6 3 3 9 9 8 6 HEAT-like repeat Adaptin_N PF01602.15 ETS80309.1 - 7.7e-14 50.9 7.4 2.4e-07 29.4 0.2 3.3 2 1 1 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.8 ETS80309.1 - 1.4e-12 47.2 8.5 0.0017 17.4 1.0 3.3 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 ETS80309.1 - 8e-09 35.0 2.5 0.00025 20.2 0.8 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 ETS80309.1 - 8.5e-09 33.8 2.0 1.5e-08 33.0 1.4 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF908 PF06012.7 ETS80309.1 - 0.00019 20.8 1.4 0.54 9.4 0.1 3.8 2 1 2 4 4 4 2 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 ETS80309.1 - 0.0027 17.9 6.8 7.4 7.3 0.3 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF2454 PF10521.4 ETS80309.1 - 0.0033 16.4 0.5 0.039 12.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 ETS80309.1 - 0.015 15.6 0.2 1 9.7 0.0 3.3 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region CBS PF00571.23 ETS80310.1 - 2.4e-31 107.2 5.3 1.3e-12 47.2 0.0 4.2 4 0 0 4 4 4 4 CBS domain AAA_22 PF13401.1 ETS80310.1 - 0.097 12.8 0.2 0.76 9.9 0.0 2.3 1 1 1 3 3 3 0 AAA domain RhoGAP PF00620.22 ETS80311.1 - 7.4e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain SSURE PF11966.3 ETS80313.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-binding repeat Metallophos PF00149.23 ETS80314.1 - 6.7e-15 55.0 0.1 1.5e-14 53.9 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS80314.1 - 2.6e-06 27.3 0.0 4.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nitroreductase PF00881.19 ETS80315.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Inh PF02974.9 ETS80315.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protease inhibitor Inh FAD_binding_1 PF00667.15 ETS80316.1 - 2.7e-45 154.4 0.0 3.8e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 ETS80316.1 - 5.5e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.20 ETS80317.1 - 8.9e-18 64.7 0.6 2e-17 63.6 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS80317.1 - 2e-06 27.7 0.0 5e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS80317.1 - 2.2e-05 24.2 0.1 3.5e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS80317.1 - 5.2e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS80317.1 - 0.016 15.2 0.4 2.7 7.9 0.0 2.3 1 1 1 2 2 2 0 NADH(P)-binding Phenol_Hydrox PF02332.13 ETS80317.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Ank_2 PF12796.2 ETS80318.1 - 7.6e-23 80.6 1.5 8.7e-09 35.6 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS80318.1 - 6e-16 58.1 1.2 2.6e-07 30.6 0.0 5.9 4 2 2 6 6 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS80318.1 - 1.1e-15 57.6 5.0 0.0016 18.9 0.0 7.3 6 1 2 8 8 8 4 Ankyrin repeats (many copies) NACHT PF05729.7 ETS80318.1 - 1.3e-13 50.9 0.1 5.3e-13 48.9 0.0 2.2 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 ETS80318.1 - 2.2e-11 42.8 6.6 0.011 15.9 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.25 ETS80318.1 - 3.5e-11 42.3 6.7 9.3e-06 25.2 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat AAA_16 PF13191.1 ETS80318.1 - 9.4e-06 25.7 0.1 7.3e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETS80318.1 - 0.00019 20.3 0.0 0.00052 18.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETS80318.1 - 0.0012 19.0 0.0 0.005 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS80318.1 - 0.0021 18.2 0.0 0.0063 16.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ETS80318.1 - 0.0052 15.7 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 ETS80318.1 - 0.034 13.9 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 ETS80318.1 - 0.041 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1563 PF07599.6 ETS80318.1 - 0.34 10.8 2.5 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) SNF2_N PF00176.18 ETS80319.1 - 2.8e-61 206.9 0.3 4e-61 206.4 0.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS80319.1 - 7.7e-08 32.0 0.1 2.2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS80319.1 - 4.2e-06 26.3 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 ETS80319.1 - 8.5e-05 22.0 1.4 0.00011 21.6 0.1 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 ETS80319.1 - 0.61 9.8 6.3 0.73 9.6 1.5 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit p450 PF00067.17 ETS80320.1 - 4.9e-43 147.3 0.1 6.6e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CVNH PF08881.5 ETS80321.1 - 1.4e-09 38.0 0.0 5.8e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 CVNH domain NACHT PF05729.7 ETS80322.1 - 8.4e-10 38.5 0.1 2.1e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS80322.1 - 2.3e-07 30.9 0.0 9.6e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS80322.1 - 3.4e-05 23.9 0.7 0.00017 21.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 ETS80322.1 - 0.00051 19.6 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETS80322.1 - 0.0074 16.4 2.8 0.022 14.9 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS80322.1 - 0.0077 15.7 0.1 0.42 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 ETS80322.1 - 0.008 16.9 0.7 0.46 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 ETS80322.1 - 0.014 15.7 0.1 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 ETS80322.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 ETS80322.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 ETS80322.1 - 0.088 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 ETS80322.1 - 0.14 11.9 0.1 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Methyltransf_11 PF08241.7 ETS80323.1 - 0.0019 18.6 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80323.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 ETS80323.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF4518 PF15008.1 ETS80323.1 - 0.73 8.8 0.0 1.3 8.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SAP PF02037.22 ETS80324.1 - 6.9e-14 50.9 0.1 1.2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain API5 PF05918.6 ETS80324.1 - 0.017 13.6 7.4 0.021 13.3 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HeH PF12949.2 ETS80324.1 - 0.021 14.3 0.5 0.048 13.2 0.3 1.6 1 1 0 1 1 1 0 HeH/LEM domain MCPVI PF02993.9 ETS80324.1 - 2.2 8.3 10.5 4.1 7.4 7.3 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Hamartin PF04388.7 ETS80324.1 - 2.9 6.4 5.1 3.3 6.2 3.5 1.1 1 0 0 1 1 1 0 Hamartin protein Med3 PF11593.3 ETS80324.1 - 7.7 5.6 13.8 9.4 5.3 9.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ras PF00071.17 ETS80326.1 - 1.6e-38 131.6 0.0 2.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS80326.1 - 2.8e-09 37.4 0.0 4.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS80326.1 - 0.00068 18.9 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GST_N_3 PF13417.1 ETS80327.1 - 4e-14 52.5 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS80327.1 - 1.4e-11 44.3 0.0 4.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS80327.1 - 4.3e-11 42.6 0.0 8.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS80327.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS80327.1 - 5.1e-08 32.6 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS80327.1 - 3.6e-05 24.1 0.0 7.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 6PGD PF00393.14 ETS80328.1 - 1.4e-69 234.5 0.0 1.7e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETS80328.1 - 5.2e-36 123.9 0.0 8.6e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 ETS80328.1 - 4e-06 26.5 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS80328.1 - 1.9e-05 24.1 0.0 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 ETS80328.1 - 0.00072 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 ETS80328.1 - 0.0053 17.1 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 ETS80328.1 - 0.0073 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS80328.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 ETS80328.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Methyltransf_18 PF12847.2 ETS80328.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Raptor_N PF14538.1 ETS80329.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 ETS80329.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DUF4599 PF15371.1 ETS80330.1 - 0.056 13.5 5.0 0.08 13.0 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) zf-rbx1 PF12678.2 ETS80331.1 - 2.5e-09 37.1 1.4 4.9e-09 36.1 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS80331.1 - 2.7e-08 33.5 7.4 1.4e-07 31.2 5.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS80331.1 - 5.8e-07 29.0 0.8 9.8e-07 28.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS80331.1 - 9.1e-07 28.5 2.1 2.1e-06 27.3 1.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS80331.1 - 2.5e-05 23.8 4.5 0.00012 21.6 3.1 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS80331.1 - 0.00016 21.6 2.3 0.00016 21.6 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 ETS80331.1 - 0.0091 15.8 0.6 0.023 14.5 0.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 ETS80331.1 - 0.018 14.7 2.6 0.04 13.6 0.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger PQ-loop PF04193.9 ETS80331.1 - 0.063 12.8 1.4 0.22 11.1 1.0 1.9 1 0 0 1 1 1 0 PQ loop repeat DUF2921 PF11145.3 ETS80331.1 - 0.42 8.2 0.2 0.66 7.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FANCL_C PF11793.3 ETS80331.1 - 1.6 8.7 4.0 5.9 6.9 2.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain HSBP1 PF06825.7 ETS80332.1 - 9.1e-17 60.3 0.8 1.1e-16 60.1 0.6 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 ETS80332.1 - 0.011 15.0 0.2 0.3 10.5 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin UBN2 PF14223.1 ETS80332.1 - 0.013 15.2 0.1 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1664 PF07889.7 ETS80332.1 - 0.024 14.4 0.2 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2884 PF11101.3 ETS80332.1 - 0.031 13.6 0.3 0.036 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MtrB PF05440.7 ETS80332.1 - 0.11 12.5 0.3 7 6.7 0.0 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DELLA PF12041.3 ETS80332.1 - 0.13 11.9 2.5 0.75 9.5 0.3 2.0 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal Thioredoxin PF00085.15 ETS80333.1 - 1.8e-61 204.3 0.0 2.3e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 ETS80333.1 - 1.6e-23 83.1 0.6 3.1e-23 82.1 0.1 1.8 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 ETS80333.1 - 1.4e-19 70.3 0.9 5.2e-09 36.2 0.0 3.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETS80333.1 - 5.1e-14 52.0 0.0 1.1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 ETS80333.1 - 3.7e-12 46.2 0.0 0.00019 21.5 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 ETS80333.1 - 6.6e-08 32.2 0.2 0.0093 15.6 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 ETS80333.1 - 1.3e-06 28.0 0.0 0.0011 18.4 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 ETS80333.1 - 3.1e-06 27.3 0.1 1 9.3 0.0 4.1 2 2 2 4 4 4 2 Thioredoxin ERp29_N PF07912.8 ETS80333.1 - 3.5e-06 26.9 0.1 4e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Redoxin PF08534.5 ETS80333.1 - 9e-06 25.2 0.5 0.012 15.1 0.1 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.6 ETS80333.1 - 0.00028 20.7 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 ETS80333.1 - 0.00034 20.3 0.0 0.43 10.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.19 ETS80333.1 - 0.019 14.9 1.1 8 6.5 0.1 3.0 2 2 0 2 2 2 0 Glutaredoxin TraF PF13728.1 ETS80333.1 - 0.021 14.2 0.0 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Flagellin_IN PF07196.8 ETS80333.1 - 0.025 14.5 0.1 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Flagellin hook IN motif Ribosomal_S14 PF00253.16 ETS80334.1 - 3.2e-18 64.8 4.3 3.4e-18 64.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 ETS80334.1 - 0.0086 15.8 0.6 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Toxin_17 PF08086.6 ETS80334.1 - 0.76 9.8 4.0 0.51 10.4 0.2 2.0 1 1 1 2 2 2 0 Ergtoxin family Prim_Zn_Ribbon PF08273.7 ETS80334.1 - 1.2 9.3 3.8 16 5.7 0.1 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase GTP_EFTU PF00009.22 ETS80335.1 - 1.3e-59 200.7 0.1 1.7e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS80335.1 - 2.1e-26 91.9 0.1 1.4e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS80335.1 - 1.4e-16 60.3 3.3 1.4e-16 60.3 2.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS80335.1 - 1.4e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 ETS80335.1 - 0.00045 19.7 0.8 0.0016 18.0 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 ETS80335.1 - 0.0005 20.5 0.0 0.00089 19.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 ETS80335.1 - 0.061 12.8 0.1 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2306 PF10067.4 ETS80335.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Ribosomal_60s PF00428.14 ETS80337.1 - 1.8 8.9 23.5 1.4 9.3 6.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein NAD_kinase PF01513.16 ETS80338.1 - 5e-68 228.9 0.0 7.3e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase CTP_transf_1 PF01148.15 ETS80339.1 - 2e-07 30.9 10.5 2e-07 30.9 7.3 3.0 2 1 0 2 2 2 1 Cytidylyltransferase family Fungal_trans PF04082.13 ETS80340.1 - 1e-17 63.8 0.0 1.5e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80340.1 - 1.2e-08 34.6 8.3 2e-08 34.0 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS80341.1 - 3e-41 141.2 50.1 7.2e-41 140.0 34.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS80341.1 - 1.3e-16 59.9 16.7 2.1e-16 59.2 11.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 ETS80341.1 - 0.018 14.4 1.1 0.018 14.4 0.7 1.8 2 0 0 2 2 2 0 WTF protein Stb3 PF10330.4 ETS80343.1 - 0.0012 18.5 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF3440 PF11922.3 ETS80343.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Sigma54_CBD PF04963.8 ETS80343.1 - 0.061 12.7 0.3 0.14 11.5 0.2 1.5 1 1 0 1 1 1 0 Sigma-54 factor, core binding domain Fungal_trans PF04082.13 ETS80344.1 - 1.3e-09 37.3 3.0 1.9e-09 36.7 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80344.1 - 9.9e-05 22.1 10.5 9.9e-05 22.1 7.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 ETS80345.1 - 1.2e-32 113.0 0.0 2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS80345.1 - 5.6e-10 39.1 0.0 9.6e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS80345.1 - 0.00013 21.7 0.2 0.0017 18.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2OG-FeII_Oxy PF03171.15 ETS80346.1 - 3.6e-18 65.6 0.0 1.2e-17 64.0 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS80346.1 - 1.6e-14 54.3 0.0 2.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.19 ETS80347.1 - 3.1e-42 144.7 13.2 1.6e-40 139.0 6.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS80347.1 - 4.8e-12 45.2 20.6 4.4e-06 25.6 1.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily EcsB PF05975.7 ETS80347.1 - 0.00029 19.4 3.3 0.00029 19.4 2.3 2.3 2 1 1 3 3 3 1 Bacterial ABC transporter protein EcsB IU_nuc_hydro PF01156.14 ETS80348.1 - 5.7e-47 160.4 0.0 1.3e-46 159.3 0.0 1.5 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ETRAMP PF09716.5 ETS80349.1 - 0.065 13.1 1.1 0.21 11.5 0.7 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cyd_oper_YbgE PF09600.5 ETS80349.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) TPT PF03151.11 ETS80352.1 - 2.3e-25 89.0 13.2 2.3e-25 89.0 9.2 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 ETS80352.1 - 4.1e-06 26.8 19.5 0.00051 20.0 1.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 ETS80352.1 - 0.36 9.6 16.0 4.7 6.0 11.1 2.0 1 1 0 1 1 1 0 UAA transporter family Caveolin PF01146.12 ETS80352.1 - 7.5 6.1 6.4 0.32 10.5 0.4 1.8 2 0 0 2 2 2 0 Caveolin Sec10 PF07393.6 ETS80353.1 - 8.3e-166 553.1 0.0 1.1e-165 552.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 ETS80353.1 - 4.5e-08 32.6 0.0 1.4e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS80353.1 - 4.5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain bZIP_2 PF07716.10 ETS80354.1 - 0.013 15.3 9.7 0.028 14.2 6.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 ETS80354.1 - 0.037 13.9 9.1 0.078 12.9 6.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor CDK5_activator PF03261.10 ETS80354.1 - 2.2 7.5 8.0 3.1 7.0 5.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein p450 PF00067.17 ETS80355.1 - 3.1e-67 227.0 0.0 3.9e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SMAP PF15477.1 ETS80356.1 - 8.7e-20 70.7 3.0 8.7e-20 70.7 2.1 4.7 2 1 0 2 2 2 1 Small acidic protein family TFIIF_alpha PF05793.7 ETS80356.1 - 0.0038 15.6 51.7 0.0053 15.2 35.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 ETS80356.1 - 0.04 12.3 47.5 0.049 12.0 32.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4551 PF15087.1 ETS80356.1 - 9.4 4.4 19.2 12 4.1 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.4 ETS80356.1 - 9.9 4.3 29.8 13 3.9 20.7 1.2 1 0 0 1 1 1 0 Transmembrane protein RAMP4 PF06624.7 ETS80357.1 - 2.1e-05 23.9 0.7 2.7e-05 23.6 0.5 1.2 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3523 PF12037.3 ETS80357.1 - 0.05 12.5 1.5 0.055 12.4 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) T2SF PF00482.18 ETS80357.1 - 0.069 13.0 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HSF_DNA-bind PF00447.12 ETS80358.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Mid1 PF12929.2 ETS80359.1 - 4.1e-125 417.8 11.9 5.1e-125 417.5 8.2 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 ETS80359.1 - 0.27 11.5 3.5 2 8.8 0.8 2.5 2 1 0 2 2 2 0 Fz domain TB2_DP1_HVA22 PF03134.14 ETS80360.1 - 5.4e-31 106.1 7.2 9e-31 105.4 5.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Kei1 PF08552.6 ETS80360.1 - 0.097 12.3 7.3 0.11 12.0 1.6 2.1 1 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4407 PF14362.1 ETS80360.1 - 0.35 9.7 0.1 0.35 9.7 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Bestrophin PF01062.16 ETS80360.1 - 6.3 5.6 15.1 76 2.0 10.5 2.0 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.10 ETS80361.1 - 1.2e-28 99.0 0.0 2.4e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.23 ETS80362.1 - 2.8e-37 128.5 0.0 5.8e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 ETS80362.1 - 1.2e-14 53.4 0.5 1.4e-09 37.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 ETS80362.1 - 1.6e-13 49.9 4.5 1.7e-09 37.0 0.2 2.6 2 0 0 2 2 2 2 ACT domain DUF3375 PF11855.3 ETS80362.1 - 0.083 11.6 0.1 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF3812 PF12757.2 ETS80364.1 - 7.7e-38 129.3 12.8 7.7e-38 129.3 8.9 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3812) DAGK_cat PF00781.19 ETS80364.1 - 0.26 10.7 0.0 0.26 10.7 0.0 3.0 3 1 0 3 3 3 0 Diacylglycerol kinase catalytic domain Y_phosphatase3 PF13350.1 ETS80365.1 - 1.2e-32 113.4 1.3 7.5e-31 107.5 0.9 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 ETS80365.1 - 2.8e-08 33.7 0.1 4.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 ETS80365.1 - 7.2e-06 25.4 0.0 1.6e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 ETS80365.1 - 0.0051 16.1 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 ETS80365.1 - 0.01 14.6 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.15 ETS80365.1 - 0.036 13.6 0.1 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_12 PF08242.7 ETS80366.1 - 1.7e-14 54.0 0.0 4.5e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80366.1 - 2.5e-11 43.5 0.1 6.1e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80366.1 - 2e-10 41.0 0.0 6.3e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS80366.1 - 6.4e-10 39.3 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80366.1 - 3e-09 37.4 0.0 8.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80366.1 - 7.9e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS80366.1 - 1.4e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS80366.1 - 1.8e-05 24.7 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS80366.1 - 4.8e-05 22.8 0.0 9.8e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 ETS80366.1 - 0.0071 17.1 0.0 0.032 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS80366.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 ETS80366.1 - 0.092 11.6 0.0 3.5 6.5 0.0 2.3 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Polyketide_cyc PF03364.15 ETS80367.1 - 2.8e-23 82.3 0.0 7.9e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 ETS80367.1 - 0.00077 19.6 0.4 0.17 12.0 0.1 2.1 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport TPR_11 PF13414.1 ETS80369.1 - 8.9e-09 34.8 0.1 4.6e-07 29.4 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.1 ETS80369.1 - 8.5e-08 32.1 5.9 0.0029 18.1 0.0 5.2 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80369.1 - 1.5e-07 31.9 4.2 0.00046 20.7 0.1 3.7 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETS80369.1 - 3.4e-06 27.3 2.8 0.27 11.6 0.1 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80369.1 - 1.2e-05 24.8 2.9 0.00043 19.9 0.0 4.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS80369.1 - 1.4e-05 24.9 0.0 0.49 10.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80369.1 - 0.0013 18.3 0.0 0.18 11.6 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS80369.1 - 0.0016 17.9 0.0 0.0093 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS80369.1 - 0.014 15.2 0.9 0.034 13.9 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS80369.1 - 0.016 15.2 0.3 0.61 10.2 0.0 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS80369.1 - 0.058 13.5 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETS80369.1 - 0.2 11.6 4.1 1.2 9.0 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Adaptin_N PF01602.15 ETS80370.1 - 1.9e-83 280.6 0.0 2.6e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETS80370.1 - 0.00012 22.2 0.7 0.15 12.3 0.0 3.4 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 ETS80370.1 - 0.011 15.7 0.0 1.7 8.9 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Glyco_hydro_43 PF04616.9 ETS80371.1 - 2e-50 171.5 2.3 2.5e-50 171.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 ETS80371.1 - 6.3e-38 129.7 0.3 1.4e-37 128.6 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 ETS80371.1 - 0.0016 17.8 2.0 0.0036 16.7 1.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_3 PF00933.16 ETS80372.1 - 2.3e-63 213.9 0.0 3.3e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS80372.1 - 5.1e-35 121.0 0.1 8.2e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Frag1 PF10277.4 ETS80373.1 - 3.9e-42 144.1 17.1 4.7e-42 143.9 11.9 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1275 PF06912.6 ETS80373.1 - 1.5 7.9 11.1 0.71 9.0 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF3611 PF12263.3 ETS80373.1 - 3.3 7.0 11.8 3.2 7.0 3.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) Pkinase PF00069.20 ETS80374.1 - 1.8e-65 220.7 0.0 2.2e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80374.1 - 1.4e-34 119.3 0.0 1.9e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80374.1 - 0.0025 16.8 0.0 0.0053 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like IGR PF09597.5 ETS80375.1 - 3.1e-22 78.2 0.0 5e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif SNF2_N PF00176.18 ETS80376.1 - 5.9e-57 192.7 0.0 1.1e-56 191.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 ETS80376.1 - 2.2e-08 33.7 11.6 4.9e-08 32.6 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS80376.1 - 1.2e-07 31.2 10.5 2.6e-07 30.2 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS80376.1 - 2.6e-07 30.1 8.7 5.4e-07 29.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS80376.1 - 3e-06 26.8 9.1 5.8e-06 25.9 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS80376.1 - 3.8e-06 26.8 10.7 7.9e-06 25.8 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS80376.1 - 8.8e-05 22.5 4.2 0.00021 21.3 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Mob_synth_C PF06463.8 ETS80376.1 - 0.0058 16.3 1.6 0.026 14.2 1.1 2.1 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 ETS80376.1 - 0.027 14.3 4.4 0.057 13.2 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETS80376.1 - 0.033 14.0 10.4 0.064 13.1 7.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETS80376.1 - 0.034 13.7 8.0 0.097 12.2 2.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Helicase_C PF00271.26 ETS80376.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_6 PF14835.1 ETS80376.1 - 0.1 12.3 5.2 0.28 10.9 3.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 ETS80376.1 - 2 8.1 9.1 6.7 6.5 6.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 ETS80376.1 - 4.1 7.0 9.6 10 5.7 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 ETS80376.1 - 4.6 7.1 7.4 9.1 6.1 4.6 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-P11 PF03854.9 ETS80376.1 - 8.4 5.9 10.7 2.2 7.8 4.6 2.2 2 1 0 2 2 1 0 P-11 zinc finger ABC_membrane PF00664.18 ETS80377.1 - 4.7e-53 180.3 36.2 5.7e-28 98.0 13.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS80377.1 - 2e-47 160.9 0.0 1.8e-27 96.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS80377.1 - 3.7e-06 27.1 0.2 1 9.2 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS80377.1 - 3.8e-06 27.0 0.1 0.023 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 ETS80377.1 - 3.1e-05 23.3 1.9 0.08 12.1 0.3 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 ETS80377.1 - 4.2e-05 24.0 2.0 0.071 13.6 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 ETS80377.1 - 4.8e-05 22.8 0.5 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETS80377.1 - 7.6e-05 22.6 0.3 0.18 11.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 ETS80377.1 - 0.00016 22.4 0.2 0.49 11.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS80377.1 - 0.00019 20.6 0.0 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 ETS80377.1 - 0.0002 20.5 0.7 0.09 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETS80377.1 - 0.00049 19.7 1.1 0.79 9.2 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS80377.1 - 0.0015 18.6 0.3 1.6 8.8 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS80377.1 - 0.0029 17.0 0.0 0.64 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS80377.1 - 0.0049 16.3 1.0 2.8 7.2 0.0 2.8 3 0 0 3 3 2 2 AAA-like domain MobB PF03205.9 ETS80377.1 - 0.012 15.2 0.7 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 ETS80377.1 - 0.019 14.4 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 ETS80377.1 - 0.022 14.5 2.6 0.39 10.5 0.2 2.7 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 ETS80377.1 - 0.023 13.3 0.6 1.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 ETS80377.1 - 0.034 14.0 0.4 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS80377.1 - 0.047 13.4 0.5 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 ETS80377.1 - 0.099 12.2 1.0 0.58 9.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 ETS80377.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain cobW PF02492.14 ETS80377.1 - 0.17 11.3 2.4 0.5 9.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 ETS80377.1 - 0.2 11.1 1.3 17 4.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 ETS80377.1 - 0.21 10.3 6.9 1 8.0 0.1 2.6 3 0 0 3 3 2 0 ArgK protein DUF87 PF01935.12 ETS80377.1 - 0.23 11.2 9.4 0.1 12.3 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_15 PF13175.1 ETS80377.1 - 0.55 9.2 1.0 6.6 5.6 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain Fcf1 PF04900.7 ETS80379.1 - 7.7e-37 125.4 0.6 1.3e-36 124.6 0.0 1.6 2 0 0 2 2 2 1 Fcf1 DUF3987 PF13148.1 ETS80379.1 - 0.83 8.1 3.3 1 7.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) N-SET PF11764.3 ETS80380.1 - 6.4e-41 140.0 1.0 6.4e-41 140.0 0.7 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 ETS80380.1 - 5.6e-24 85.2 0.2 5.6e-24 85.2 0.1 3.8 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 ETS80380.1 - 1.7e-22 78.5 0.0 4.3e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_5 PF13893.1 ETS80380.1 - 0.0037 17.0 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS80380.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tropomyosin_1 PF12718.2 ETS80382.1 - 1.6e-47 160.9 35.1 2e-47 160.6 24.3 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 ETS80382.1 - 1.1e-08 34.4 30.4 4.5e-05 22.6 2.6 3.0 1 1 2 3 3 3 3 Tropomyosin Myosin_tail_1 PF01576.14 ETS80382.1 - 1.8e-05 22.7 30.8 2e-05 22.5 21.3 1.0 1 0 0 1 1 1 1 Myosin tail DUF4200 PF13863.1 ETS80382.1 - 0.00014 21.7 30.1 0.022 14.6 10.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) ATG16 PF08614.6 ETS80382.1 - 0.00016 21.5 29.2 0.0083 15.9 11.1 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.1 ETS80382.1 - 0.00035 19.8 28.5 0.013 14.7 12.4 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 ETS80382.1 - 0.0023 17.7 37.0 0.008 15.9 11.1 3.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 ETS80382.1 - 0.0023 17.0 32.7 0.027 13.5 12.7 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 ETS80382.1 - 0.0036 17.0 28.5 0.059 13.1 12.9 2.8 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding PilJ PF13675.1 ETS80382.1 - 0.0046 17.2 14.2 0.091 13.0 1.1 2.8 1 1 2 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-F_leu_zip PF10473.4 ETS80382.1 - 0.0048 16.7 32.2 0.13 12.1 9.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 ETS80382.1 - 0.0064 16.4 24.9 0.12 12.3 11.1 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Lebercilin PF15619.1 ETS80382.1 - 0.0074 15.7 31.4 0.24 10.8 12.8 2.1 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 ETS80382.1 - 0.0078 15.8 31.9 0.45 10.0 14.7 2.3 1 1 0 1 1 1 1 IncA protein BRE1 PF08647.6 ETS80382.1 - 0.0088 15.9 24.7 0.055 13.4 2.8 2.3 1 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase HAP1_N PF04849.8 ETS80382.1 - 0.011 14.6 29.4 0.028 13.3 20.4 2.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.4 ETS80382.1 - 0.012 15.7 21.2 0.17 12.0 0.6 3.1 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.4 ETS80382.1 - 0.013 15.5 9.3 0.013 15.5 6.4 2.9 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.6 ETS80382.1 - 0.014 14.1 25.4 0.028 13.0 9.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETS80382.1 - 0.014 15.1 5.7 0.014 15.1 4.0 2.2 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 ETS80382.1 - 0.016 15.4 13.0 0.76 10.0 0.1 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 ETS80382.1 - 0.017 14.3 2.6 0.72 8.9 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 ETS80382.1 - 0.019 14.9 31.6 0.081 12.8 6.1 3.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 ETS80382.1 - 0.02 12.7 16.1 0.028 12.2 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 ETS80382.1 - 0.024 14.1 32.3 0.028 13.9 11.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 ETS80382.1 - 0.029 14.3 31.1 1.9 8.5 0.6 5.1 1 1 4 5 5 5 0 bZIP transcription factor Cast PF10174.4 ETS80382.1 - 0.036 12.1 25.6 0.04 11.9 17.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone EzrA PF06160.7 ETS80382.1 - 0.041 12.0 22.2 0.033 12.3 3.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4201 PF13870.1 ETS80382.1 - 0.049 13.0 23.1 0.44 9.9 5.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HALZ PF02183.13 ETS80382.1 - 0.052 13.2 0.3 0.052 13.2 0.2 4.7 3 2 1 4 4 3 0 Homeobox associated leucine zipper MIS13 PF08202.6 ETS80382.1 - 0.07 12.1 21.0 1.2 8.1 4.3 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family DUF904 PF06005.7 ETS80382.1 - 0.12 12.6 37.1 1.2 9.4 1.9 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 ETS80382.1 - 0.13 12.1 15.1 0.48 10.3 2.0 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) WXG100 PF06013.7 ETS80382.1 - 0.16 11.9 15.8 1.1 9.2 0.3 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF3166 PF11365.3 ETS80382.1 - 0.17 12.3 18.7 0.17 12.3 7.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) DUF2353 PF09789.4 ETS80382.1 - 0.19 10.9 23.4 1.9 7.6 16.3 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IFT46_B_C PF12317.3 ETS80382.1 - 0.2 10.9 5.8 0.08 12.2 2.2 1.6 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal NABP PF07990.7 ETS80382.1 - 0.21 10.8 5.4 0.23 10.6 3.8 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Filament PF00038.16 ETS80382.1 - 0.21 11.0 24.6 0.87 8.9 17.0 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF3584 PF12128.3 ETS80382.1 - 0.21 8.8 27.9 0.81 6.9 19.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2730 PF10805.3 ETS80382.1 - 0.21 11.3 13.1 0.13 12.0 1.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.6 ETS80382.1 - 0.22 11.9 17.5 2.9 8.3 5.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF972 PF06156.8 ETS80382.1 - 0.22 11.8 23.7 5 7.5 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 ETS80382.1 - 0.23 11.5 16.1 0.12 12.5 3.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 ETS80382.1 - 0.37 11.0 20.2 1.9 8.7 14.0 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CCDC155 PF14662.1 ETS80382.1 - 0.38 10.3 32.0 2.2 7.8 8.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 AAA_13 PF13166.1 ETS80382.1 - 0.53 8.6 21.9 1.5 7.1 15.2 1.7 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 ETS80382.1 - 0.58 10.6 24.7 3.5 8.1 2.2 3.4 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 ETS80382.1 - 0.71 9.6 12.3 1.8 8.3 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Striatin PF08232.7 ETS80382.1 - 0.78 10.0 25.6 3.8 7.8 11.1 2.2 1 1 0 2 2 2 0 Striatin family Fmp27_WPPW PF10359.4 ETS80382.1 - 1.1 7.5 20.7 0.16 10.3 6.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.4 ETS80382.1 - 1.2 8.0 23.4 3.9 6.3 15.1 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3287 PF11690.3 ETS80382.1 - 1.2 9.2 12.0 0.46 10.5 1.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) TPR_MLP1_2 PF07926.7 ETS80382.1 - 1.4 8.6 33.4 1.1 8.9 11.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPIP PF06409.6 ETS80382.1 - 1.4 7.5 6.6 1.7 7.3 4.6 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Jnk-SapK_ap_N PF09744.4 ETS80382.1 - 1.5 8.8 24.7 0.21 11.5 10.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF724 PF05266.9 ETS80382.1 - 1.6 8.3 23.6 1.4 8.4 6.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HOOK PF05622.7 ETS80382.1 - 1.7 6.3 26.8 17 3.0 18.7 2.1 1 1 0 1 1 1 0 HOOK protein HalX PF08663.5 ETS80382.1 - 2 8.4 19.8 1.9 8.5 1.1 4.1 1 1 2 3 3 3 0 HalX domain DUF3450 PF11932.3 ETS80382.1 - 2 7.5 24.2 2.6 7.2 9.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4482 PF14818.1 ETS80382.1 - 2.1 9.0 26.4 0.4 11.3 2.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) Nsp1_C PF05064.8 ETS80382.1 - 2.3 7.9 23.7 0.2 11.3 4.7 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DivIC PF04977.10 ETS80382.1 - 2.6 7.5 34.6 0.44 10.0 3.0 4.5 1 1 3 4 4 3 0 Septum formation initiator Nup54 PF13874.1 ETS80382.1 - 2.7 7.6 21.3 5 6.7 3.9 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Cortex-I_coil PF09304.5 ETS80382.1 - 2.9 7.9 28.5 2.3 8.2 6.0 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Kinetocho_Slk19 PF12709.2 ETS80382.1 - 2.9 8.0 25.8 4 7.5 7.6 3.3 1 1 2 3 3 3 0 Central kinetochore-associated zf-C4H2 PF10146.4 ETS80382.1 - 3.2 7.7 18.7 0.077 13.0 7.2 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein Uds1 PF15456.1 ETS80382.1 - 3.6 7.5 23.1 7 6.6 1.6 2.6 1 1 1 2 2 2 0 Up-regulated During Septation Prefoldin_2 PF01920.15 ETS80382.1 - 4 7.2 31.6 0.32 10.7 1.6 3.9 2 1 2 4 4 4 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 ETS80382.1 - 4.2 7.4 28.1 3.6 7.6 0.9 3.3 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 ETS80382.1 - 4.5 5.5 6.5 5.5 5.3 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 ETS80382.1 - 4.7 6.0 23.3 1 8.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.7 ETS80382.1 - 4.9 7.6 25.6 9.5 6.6 3.8 3.9 1 1 3 4 4 4 0 SlyX MAD PF05557.8 ETS80382.1 - 6.1 4.8 28.9 1.8 6.5 10.3 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein HD_3 PF13023.1 ETS80382.1 - 6.8 6.4 11.5 1.7 8.3 5.5 1.7 1 1 1 2 2 2 0 HD domain rRNA_proc-arch PF13234.1 ETS80382.1 - 6.8 5.7 15.3 0.67 9.0 3.5 2.5 1 1 1 2 2 2 0 rRNA-processing arch domain DUF4618 PF15397.1 ETS80382.1 - 7.2 5.8 22.8 19 4.4 15.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Occludin_ELL PF07303.8 ETS80382.1 - 7.2 7.4 19.3 1.5 9.5 0.7 3.4 1 1 2 3 3 3 0 Occludin homology domain Rootletin PF15035.1 ETS80382.1 - 7.3 6.5 26.4 30 4.5 18.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 ETS80382.1 - 7.4 4.8 23.5 0.21 9.9 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) HSP70 PF00012.15 ETS80382.1 - 9 4.0 17.7 11 3.7 12.3 1.1 1 0 0 1 1 1 0 Hsp70 protein Mnd1 PF03962.10 ETS80382.1 - 9 5.9 27.7 3.5 7.2 9.5 2.3 1 1 1 2 2 2 0 Mnd1 family Mst1_SARAH PF11629.3 ETS80382.1 - 9.4 6.1 16.0 0.4 10.5 0.6 3.7 3 1 1 4 4 4 0 C terminal SARAH domain of Mst1 Prefoldin PF02996.12 ETS80382.1 - 9.7 5.8 27.3 0.29 10.7 1.7 3.9 1 1 3 4 4 4 0 Prefoldin subunit DUF812 PF05667.6 ETS80382.1 - 9.8 4.5 21.6 26 3.1 14.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Sas10_Utp3 PF04000.10 ETS80382.1 - 9.9 6.4 18.8 23 5.2 0.1 3.8 2 1 1 3 3 3 0 Sas10/Utp3/C1D family Nop25 PF09805.4 ETS80383.1 - 3.6e-36 124.2 15.4 3.6e-36 124.2 10.7 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EIIBC-GUT_N PF03612.9 ETS80383.1 - 1.3 8.6 10.6 1.4 8.5 2.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_S1 PF05827.7 ETS80384.1 - 6.4e-32 110.9 1.0 1.3e-31 109.9 0.7 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF829 PF05705.9 ETS80384.1 - 0.02 14.5 0.1 1.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF829) BRICHOS PF04089.9 ETS80384.1 - 0.043 13.6 0.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 BRICHOS domain Trm112p PF03966.11 ETS80385.1 - 5.5e-17 61.9 0.1 7.1e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 ETS80385.1 - 0.021 15.1 0.2 0.036 14.3 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain RRN7 PF11781.3 ETS80385.1 - 0.17 11.4 1.1 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Pro_isomerase PF00160.16 ETS80386.1 - 2.8e-46 157.5 0.4 3.7e-46 157.1 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 ETS80387.1 - 4.6e-18 65.6 0.1 4.9e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.16 ETS80388.1 - 1.4e-101 339.6 0.0 1.6e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.22 ETS80389.1 - 1.5e-16 60.3 0.3 4.6e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 ETS80389.1 - 4.5e-16 58.8 0.1 3.7e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 ETS80389.1 - 7.9e-13 47.9 0.0 1.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3993 PF13158.1 ETS80389.1 - 0.047 13.4 0.4 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) DUF3504 PF12012.3 ETS80389.1 - 0.85 9.3 3.9 13 5.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) SNF2_N PF00176.18 ETS80390.1 - 1.4e-76 257.1 0.2 2.1e-76 256.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS80390.1 - 4.1e-11 42.5 0.1 7e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS80390.1 - 9.5e-06 25.1 0.0 3.2e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS80390.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 ETS80390.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 Pkinase PF00069.20 ETS80391.1 - 3.3e-26 92.0 0.0 8.1e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80391.1 - 1.6e-19 70.0 0.0 3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 ETS80391.1 - 7.2e-09 35.5 0.1 5.4e-08 32.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 ETS80391.1 - 2.1e-06 27.9 0.1 8.1e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80391.1 - 8.3e-06 25.3 1.6 0.0011 18.6 0.2 3.0 2 0 0 2 2 2 1 Ankyrin repeat AAA_16 PF13191.1 ETS80391.1 - 3.8e-05 23.7 0.0 0.00038 20.4 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS80391.1 - 0.00016 21.7 0.1 0.00098 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 ETS80391.1 - 0.00037 20.9 0.2 0.0025 18.2 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80391.1 - 0.0033 17.5 0.6 0.091 13.0 0.1 3.2 2 0 0 2 2 2 1 Ankyrin repeat KaiC PF06745.8 ETS80391.1 - 0.0041 16.2 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 ETS80391.1 - 0.027 14.3 0.1 0.65 9.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 ETS80391.1 - 0.065 12.0 0.2 0.26 10.1 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain AAA PF00004.24 ETS80391.1 - 0.13 12.5 0.5 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HD PF01966.17 ETS80392.1 - 0.08 12.9 0.1 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 HD domain HET PF06985.6 ETS80393.1 - 7.8e-34 116.8 3.6 1.4e-33 116.0 2.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GPS PF01825.16 ETS80393.1 - 0.018 15.1 1.2 0.034 14.2 0.1 2.1 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain SLAC1 PF03595.12 ETS80394.1 - 2e-79 266.6 42.8 2.3e-79 266.4 29.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_cc PF11790.3 ETS80395.1 - 3e-53 180.6 0.0 3.6e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TMF_DNA_bd PF12329.3 ETS80396.1 - 0.00034 20.3 38.1 0.15 11.8 0.0 6.7 3 2 3 6 6 6 3 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 ETS80396.1 - 0.00086 18.0 7.8 0.00086 18.0 5.4 3.9 3 1 0 3 3 3 2 Spc7 kinetochore protein TBPIP PF07106.8 ETS80396.1 - 0.0021 17.6 23.7 0.086 12.3 1.4 4.2 3 1 1 4 4 4 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 ETS80396.1 - 0.0028 17.5 21.5 0.019 14.8 1.9 3.7 3 0 0 3 3 3 2 FlxA-like protein Reo_sigmaC PF04582.7 ETS80396.1 - 0.021 14.0 12.5 4.5 6.3 0.0 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 ETS80396.1 - 0.11 12.3 16.1 0.21 11.4 0.1 6.2 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 ETS80396.1 - 0.18 11.2 24.5 0.017 14.5 1.5 4.1 3 1 1 4 4 4 0 Phage minor structural protein GP20 AAA_13 PF13166.1 ETS80396.1 - 0.2 10.0 18.2 0.051 12.0 4.0 3.3 3 1 0 3 3 3 0 AAA domain Filament PF00038.16 ETS80396.1 - 0.26 10.7 35.3 0.49 9.8 4.3 5.0 3 1 2 5 5 5 0 Intermediate filament protein GAS PF13851.1 ETS80396.1 - 0.99 8.5 28.8 1.2 8.3 4.4 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3571 PF12095.3 ETS80396.1 - 1.9 8.8 9.3 10 6.4 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) TMPIT PF07851.8 ETS80396.1 - 1.9 7.4 15.0 2.8 6.9 1.1 3.3 3 1 0 3 3 3 0 TMPIT-like protein Syntaxin-6_N PF09177.6 ETS80396.1 - 5.1 7.5 19.1 0.33 11.3 1.5 4.8 3 3 1 4 4 4 0 Syntaxin 6, N-terminal DUF2730 PF10805.3 ETS80396.1 - 6 6.6 16.7 8.2 6.2 0.3 5.3 3 1 2 5 5 5 0 Protein of unknown function (DUF2730) TPD52 PF04201.10 ETS80396.1 - 6.1 6.5 18.6 1.9 8.1 0.6 4.2 3 2 0 3 3 3 0 Tumour protein D52 family APG6 PF04111.7 ETS80396.1 - 6.6 5.6 27.8 0.027 13.5 3.6 3.8 3 1 1 4 4 4 0 Autophagy protein Apg6 RIO1 PF01163.17 ETS80397.1 - 1e-67 227.1 0.9 1.8e-67 226.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 ETS80397.1 - 0.0011 18.8 0.4 0.068 12.8 0.3 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS80397.1 - 0.0038 16.3 0.7 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.18 ETS80398.1 - 1.8e-11 44.0 9.7 1.8e-11 44.0 6.7 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 ETS80398.1 - 0.0022 17.5 1.5 0.0022 17.5 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF588) Peptidase_M56 PF05569.6 ETS80398.1 - 0.011 14.7 0.6 0.015 14.2 0.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1761 PF08570.5 ETS80398.1 - 9.5 6.2 12.0 0.46 10.4 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Metallophos PF00149.23 ETS80399.1 - 2.3e-09 36.9 0.7 9.8e-09 34.8 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS80399.1 - 2.1e-06 27.6 0.0 3.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CATSPERD PF15020.1 ETS80399.1 - 0.073 11.0 0.0 0.11 10.4 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Ank_2 PF12796.2 ETS80400.1 - 3.6e-11 43.2 0.1 2.4e-06 27.7 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS80400.1 - 2.5e-09 37.4 0.9 0.024 15.1 0.0 4.1 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS80400.1 - 1.7e-06 27.5 0.2 1 9.3 0.0 5.2 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 ETS80400.1 - 1.8e-06 27.5 1.6 0.041 14.1 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 ETS80400.1 - 2e-05 24.6 0.1 0.042 14.1 0.0 3.9 3 1 3 6 6 6 2 Ankyrin repeats (many copies) HET PF06985.6 ETS80401.1 - 5.5e-17 62.2 7.4 9.9e-17 61.3 0.4 2.8 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS80401.1 - 8.2e-07 28.8 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS80401.1 - 0.0011 19.1 0.0 0.025 14.7 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 ETS80401.1 - 0.018 15.2 0.0 0.071 13.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS80401.1 - 0.022 14.7 0.0 0.11 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 ETS80401.1 - 0.03 13.3 0.1 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 ETS80401.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 ETS80401.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Ank PF00023.25 ETS80402.1 - 3.9e-37 124.2 8.6 4.7e-09 35.6 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 ETS80402.1 - 3.8e-36 123.2 9.5 1.9e-19 69.8 1.4 3.3 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS80402.1 - 4.9e-27 93.8 4.4 2.5e-12 46.9 0.2 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80402.1 - 1.1e-26 90.2 9.0 7.5e-07 28.7 0.0 6.1 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.1 ETS80402.1 - 8.1e-17 60.8 7.2 0.00014 21.9 0.1 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.7 ETS80402.1 - 1e-09 38.2 0.3 3e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS80402.1 - 1.1e-05 25.5 8.0 5.1e-05 23.3 0.4 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS80402.1 - 0.0025 17.9 0.8 0.051 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain UBA PF00627.26 ETS80402.1 - 0.0054 16.5 0.1 32 4.5 0.0 4.3 4 0 0 4 4 4 0 UBA/TS-N domain HrpJ PF07201.6 ETS80402.1 - 0.0078 16.2 2.2 0.038 13.9 0.1 2.9 2 0 0 2 2 2 1 HrpJ-like domain AAA_14 PF13173.1 ETS80402.1 - 0.014 15.2 0.0 0.27 11.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 ETS80402.1 - 0.018 13.9 0.0 0.36 9.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain FlgN PF05130.7 ETS80402.1 - 0.099 12.8 3.5 0.17 12.1 1.2 2.3 2 0 0 2 2 2 0 FlgN protein AAA_13 PF13166.1 ETS80402.1 - 0.19 10.1 1.8 0.36 9.2 1.3 1.4 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 ETS80402.1 - 0.23 11.5 10.0 7.2 6.7 0.2 5.1 5 0 0 5 5 4 0 Domain of unknown function (DUF1843) V-SNARE PF05008.10 ETS80402.1 - 0.41 10.8 3.4 0.49 10.5 0.2 2.8 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMF_TATA_bd PF12325.3 ETS80402.1 - 0.47 10.1 8.0 2.7 7.7 5.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding p450 PF00067.17 ETS80403.1 - 1.9e-30 105.8 0.0 1.7e-29 102.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 EutN_CcmL PF03319.8 ETS80403.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome p450 PF00067.17 ETS80404.1 - 3.9e-51 174.0 0.1 4.9e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 ETS80405.1 - 1.1e-19 70.1 0.0 4.4e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Transferase family Mito_carr PF00153.22 ETS80406.1 - 1e-42 143.7 9.4 1.6e-18 66.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 ETS80407.1 - 2.1e-08 33.9 9.6 3.8e-08 33.1 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 ETS80408.1 - 7.5e-43 146.4 0.0 9.2e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family p450 PF00067.17 ETS80409.1 - 3.8e-55 187.2 0.0 5.6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.19 ETS80409.1 - 1.1e-29 103.4 1.8 1.1e-29 103.4 1.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS80409.1 - 2.6e-21 76.3 0.0 1e-20 74.3 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS80409.1 - 2.8e-20 71.5 0.7 5.4e-20 70.6 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS80409.1 - 7e-07 29.5 2.2 1.4e-06 28.5 1.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.21 ETS80410.1 - 1.8e-08 34.0 0.3 5.2e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS80410.1 - 2.6e-08 33.5 0.0 6.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS80410.1 - 0.00023 22.0 0.0 0.00049 20.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FSH1 PF03959.8 ETS80411.1 - 9.2e-34 116.7 0.0 1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 ETS80411.1 - 2.9e-05 23.6 0.2 0.00013 21.4 0.2 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.21 ETS80412.1 - 7.8e-75 251.6 0.0 1.4e-74 250.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 ETS80412.1 - 2.1e-49 168.3 0.0 3.1e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 ETS80412.1 - 3.5e-48 164.5 0.0 6.6e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 ETS80412.1 - 4.6e-48 163.2 0.0 1.1e-47 162.0 0.0 1.7 1 0 0 1 1 1 1 KR domain Condensation PF00668.15 ETS80412.1 - 1.7e-40 138.7 0.1 3.2e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 ETS80412.1 - 6.4e-40 136.7 0.0 1.8e-39 135.3 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS80412.1 - 5.4e-32 110.1 0.3 2e-31 108.3 0.0 2.2 3 0 0 3 3 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS80412.1 - 3.5e-19 69.1 0.0 1.2e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80412.1 - 8.8e-15 54.7 0.4 2.2e-14 53.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80412.1 - 3.6e-12 46.6 0.0 1e-11 45.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80412.1 - 1.5e-10 41.6 0.0 2e-09 38.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80412.1 - 5.3e-10 39.0 0.0 1.5e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 ETS80412.1 - 2.8e-07 30.6 0.2 8.4e-07 29.1 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 ETS80412.1 - 3.7e-06 27.1 0.0 3.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 HxxPF-repeated domain Methyltransf_16 PF10294.4 ETS80412.1 - 5.8e-06 25.8 0.0 9.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 ETS80412.1 - 0.0001 21.7 0.0 0.00032 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS80412.1 - 0.00024 20.2 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 ETS80412.1 - 0.00027 20.5 0.0 0.00073 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Thiolase_N PF00108.18 ETS80412.1 - 0.0017 17.3 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 ETS80412.1 - 0.023 13.7 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 ETS80412.1 - 0.19 10.5 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase ketoacyl-synt PF00109.21 ETS80413.1 - 6.4e-73 245.3 1.6 8.7e-73 244.9 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS80413.1 - 2.2e-61 206.7 0.5 1.1e-60 204.4 0.3 2.4 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 ETS80413.1 - 1.8e-54 185.2 0.1 1.1e-53 182.7 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.1 ETS80413.1 - 2e-49 168.3 0.2 5.8e-49 166.8 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS80413.1 - 8.5e-48 162.4 0.4 8.5e-48 162.4 0.3 4.4 6 0 0 6 6 6 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS80413.1 - 2.3e-36 124.2 0.8 7.1e-36 122.6 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS80413.1 - 1.4e-13 51.1 0.0 4.9e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80413.1 - 2e-11 43.8 0.0 5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80413.1 - 1.8e-06 27.6 0.0 8.9e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 ETS80413.1 - 1.9e-05 24.8 0.7 5.7e-05 23.3 0.5 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 ETS80413.1 - 4.8e-05 22.5 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ETS80413.1 - 6.9e-05 23.2 0.0 0.00055 20.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS80413.1 - 0.00011 21.7 0.4 0.0014 18.1 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.1 ETS80413.1 - 0.00028 21.1 0.0 0.0011 19.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80413.1 - 0.00064 20.2 0.0 0.0064 17.0 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Thiolase_N PF00108.18 ETS80413.1 - 0.028 13.4 0.7 0.16 10.9 0.3 2.1 2 0 0 2 2 2 0 Thiolase, N-terminal domain Transferase PF02458.10 ETS80414.1 - 8.8e-12 44.1 0.0 2.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Transferase family adh_short PF00106.20 ETS80415.1 - 9.2e-14 51.6 0.2 1.5e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS80415.1 - 4.3e-05 23.0 0.1 0.0015 18.0 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS80415.1 - 0.00047 19.8 0.2 0.0062 16.2 0.0 2.3 2 1 1 3 3 3 1 KR domain TrkA_N PF02254.13 ETS80415.1 - 0.011 15.6 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 ETS80416.1 - 1e-17 64.3 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS80416.1 - 6.8e-15 54.5 0.0 1.4e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS80416.1 - 1.5e-10 41.4 0.1 7.6e-10 39.0 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS80416.1 - 4e-09 36.6 0.0 8.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS80416.1 - 5.1e-09 35.4 0.0 8.1e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS80416.1 - 6.2e-09 35.1 0.0 6.2e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETS80416.1 - 1.4e-06 27.7 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 ETS80416.1 - 8e-05 22.3 0.0 0.00029 20.5 0.0 1.8 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 ETS80416.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 ETS80416.1 - 0.043 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ETS80416.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_2 PF07883.6 ETS80417.1 - 6.1e-07 28.8 0.1 9.3e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.18 ETS80418.1 - 3e-25 88.3 1.7 6.1e-25 87.3 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS80418.1 - 9.5e-07 28.6 0.1 2.4e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4148 PF13663.1 ETS80418.1 - 0.12 12.1 0.2 0.35 10.7 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) Methyltransf_12 PF08242.7 ETS80419.1 - 5.8e-17 61.9 0.0 2.3e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80419.1 - 3.1e-13 49.7 0.0 5.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80419.1 - 1.5e-11 44.0 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80419.1 - 6.6e-07 29.7 0.0 2.1e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80419.1 - 9.3e-07 29.4 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 ETS80419.1 - 7.6e-06 24.9 0.0 1.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_25 PF13649.1 ETS80419.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS80419.1 - 0.00043 19.4 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS80419.1 - 0.0029 17.6 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETS80419.1 - 0.0041 16.5 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 ETS80419.1 - 0.0087 15.1 0.1 0.017 14.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 ETS80419.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.7 ETS80419.1 - 0.019 14.2 0.0 0.045 13.0 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.4 ETS80419.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 ETS80420.1 - 1.2e-52 179.0 0.0 1.6e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS80421.1 - 1.8e-23 83.2 3.2 3e-23 82.5 2.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS80421.1 - 5.5e-15 55.7 0.3 7.4e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 ETS80421.1 - 4.2e-08 32.6 0.0 3.2e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 ETS80421.1 - 2.1e-05 24.2 2.0 3.6e-05 23.4 1.4 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ETS80421.1 - 0.0013 17.7 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETS80421.1 - 0.0028 17.6 0.1 0.0044 17.0 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS80421.1 - 0.0048 16.1 0.0 0.025 13.8 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_2 PF03446.10 ETS80421.1 - 0.0075 16.1 0.7 0.013 15.3 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.2 ETS80422.1 - 9.8e-42 141.2 6.0 1.5e-17 63.7 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80422.1 - 2.9e-25 86.7 7.7 7.9e-08 31.7 0.3 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS80422.1 - 4.4e-22 78.0 6.9 1.9e-09 37.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS80422.1 - 4.8e-21 74.3 1.9 4.4e-11 42.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80422.1 - 1.7e-19 67.9 2.8 1.1e-05 25.2 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.16 ETS80422.1 - 0.043 13.7 7.8 0.1 12.5 5.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.18 ETS80423.1 - 8.4e-18 64.1 1.8 2.2e-17 62.8 1.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS80423.1 - 7.3e-11 41.8 1.6 2.3e-10 40.2 0.5 2.4 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS80423.1 - 0.063 12.4 0.2 0.097 11.7 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Abhydrolase_6 PF12697.2 ETS80424.1 - 2.9e-21 76.3 0.1 3.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80424.1 - 4.7e-18 65.3 0.0 8.9e-18 64.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS80424.1 - 2.4e-10 39.4 0.1 4.6e-05 22.0 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 ETS80424.1 - 1.8e-08 33.8 0.0 4.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 ETS80424.1 - 7.4e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 ETS80424.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 ETS80424.1 - 0.0018 16.9 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 ETS80424.1 - 0.12 11.6 0.0 0.43 9.8 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETS80424.1 - 0.14 11.6 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.21 ETS80425.1 - 5e-60 203.1 0.0 1e-59 202.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS80425.1 - 1.1e-53 181.6 2.0 1.7e-53 180.9 0.1 2.4 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 ETS80425.1 - 3.2e-51 174.5 0.0 4.6e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 ETS80425.1 - 3e-40 138.2 0.0 5.5e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS80425.1 - 1.1e-39 136.0 0.1 5.2e-39 133.8 0.1 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS80425.1 - 1.1e-32 112.3 0.4 1.2e-31 108.9 0.3 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 ETS80425.1 - 1.7e-13 51.6 0.0 1.1e-12 48.9 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS80425.1 - 6.4e-13 48.3 0.0 2.1e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS80425.1 - 3.7e-09 36.3 0.3 8.5e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS80425.1 - 3.8e-07 30.2 1.4 6.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.17 ETS80426.1 - 5.6e-48 163.6 0.0 8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 ETS80428.1 - 1.8e-70 237.3 0.1 3.6e-70 236.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS80428.1 - 2.8e-61 206.3 0.8 5e-61 205.5 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 ETS80428.1 - 1.4e-47 161.6 0.6 2e-47 161.2 0.0 1.6 2 0 0 2 2 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 ETS80428.1 - 6.8e-19 67.7 0.7 1.5e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS80428.1 - 2.2e-15 57.6 0.0 7.3e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.17 ETS80428.1 - 4.5e-11 42.6 0.0 1.4e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_N PF08240.7 ETS80428.1 - 2.9e-06 27.0 1.0 1e-05 25.2 0.1 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 ETS80428.1 - 0.00022 20.2 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 ETS80428.1 - 0.0018 17.0 0.0 0.0046 15.6 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 ETS80428.1 - 0.0055 15.7 0.3 0.011 14.7 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 ETS80428.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HTH_15 PF12324.3 ETS80428.1 - 0.02 14.5 0.1 2.4 7.8 0.1 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase ACP_syn_III PF08545.5 ETS80428.1 - 0.16 11.6 2.0 4.8 6.9 0.8 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HEAT_2 PF13646.1 ETS80430.1 - 2.5e-18 66.1 14.3 4.3e-07 30.1 0.2 7.3 6 1 0 6 6 6 4 HEAT repeats NACHT PF05729.7 ETS80430.1 - 6.4e-16 58.4 0.0 2e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain HEAT PF02985.17 ETS80430.1 - 2.6e-08 33.2 2.1 8.3 6.7 0.0 7.1 6 0 0 6 6 6 0 HEAT repeat NB-ARC PF00931.17 ETS80430.1 - 1.1e-06 27.6 0.1 5e-06 25.5 0.0 2.1 3 0 0 3 3 2 1 NB-ARC domain HEAT_EZ PF13513.1 ETS80430.1 - 2.7e-06 27.6 3.2 5.1 7.7 0.1 7.5 7 1 1 8 8 8 1 HEAT-like repeat DUF676 PF05057.9 ETS80430.1 - 1.3e-05 24.6 0.0 3.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 ETS80430.1 - 1.6e-05 24.6 0.0 3.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 ETS80430.1 - 1.6e-05 25.0 2.1 0.0068 16.5 0.0 4.8 4 1 1 5 5 5 1 AAA domain AAA_17 PF13207.1 ETS80430.1 - 0.0003 21.6 0.0 0.0018 19.0 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS80430.1 - 0.00032 20.9 0.1 0.003 17.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 ETS80430.1 - 0.00039 20.6 0.4 0.14 12.3 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) VHS PF00790.14 ETS80430.1 - 0.0038 16.8 6.5 1.7 8.2 0.1 4.7 3 2 1 4 4 4 1 VHS domain AAA_14 PF13173.1 ETS80430.1 - 0.0047 16.8 0.0 0.018 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Lipase_3 PF01764.20 ETS80430.1 - 0.0069 16.0 0.0 0.023 14.3 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 ETS80430.1 - 0.007 16.2 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_19 PF13245.1 ETS80430.1 - 0.007 16.0 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS80430.1 - 0.01 15.8 2.5 0.058 13.3 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain Vac14_Fab1_bd PF12755.2 ETS80430.1 - 0.019 15.3 0.2 2.5 8.5 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Abhydrolase_5 PF12695.2 ETS80430.1 - 0.019 14.7 0.0 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family NTPase_1 PF03266.10 ETS80430.1 - 0.02 14.6 0.0 0.078 12.6 0.0 2.1 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 ETS80430.1 - 0.029 13.7 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 ETS80430.1 - 0.034 13.2 0.6 0.095 11.8 0.0 2.0 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.13 ETS80430.1 - 0.036 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 ETS80430.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Abhydrolase_1 PF00561.15 ETS80430.1 - 0.11 11.9 0.0 0.5 9.8 0.0 2.1 3 0 0 3 3 2 0 alpha/beta hydrolase fold ArgK PF03308.11 ETS80430.1 - 0.22 10.2 0.0 0.46 9.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein BTB PF00651.26 ETS80431.1 - 6.4e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain NmrA PF05368.8 ETS80432.1 - 2e-27 95.9 0.3 2.5e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS80432.1 - 2.3e-15 57.0 1.1 4.8e-15 56.0 0.2 1.7 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS80432.1 - 1.1e-06 28.2 0.1 2.2e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 ETS80432.1 - 9.6e-06 24.8 0.7 5.1e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase DFP PF04127.10 ETS80432.1 - 0.00057 19.5 0.8 0.0011 18.5 0.5 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DapB_N PF01113.15 ETS80432.1 - 0.00083 19.2 0.2 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 ETS80432.1 - 0.0013 19.0 0.3 0.0025 18.0 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETS80432.1 - 0.0015 17.5 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 ETS80432.1 - 0.0023 17.0 0.5 0.017 14.2 0.3 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 ETS80432.1 - 0.0027 16.4 0.0 0.0051 15.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 ETS80432.1 - 0.017 14.2 0.1 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS80432.1 - 0.02 14.5 0.2 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS80432.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 ETS80432.1 - 0.056 13.3 0.5 0.11 12.4 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase F420_oxidored PF03807.12 ETS80432.1 - 0.1 13.0 0.7 0.51 10.8 0.2 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 ETS80432.1 - 0.24 11.2 1.3 0.96 9.2 0.9 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain COesterase PF00135.23 ETS80433.1 - 1.2e-74 252.0 0.0 1.6e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS80433.1 - 2.5e-10 40.2 0.0 8.9e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS80433.1 - 0.19 10.3 0.1 1.6 7.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) PALP PF00291.20 ETS80435.1 - 6.3e-61 206.2 0.0 8.3e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 ETS80435.1 - 2.2e-09 36.9 0.0 1.5e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 CBS domain FtsJ PF01728.14 ETS80436.1 - 1.1e-12 48.2 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Amino_oxidase PF01593.19 ETS80437.1 - 3.8e-54 184.4 0.0 6.4e-54 183.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS80437.1 - 4.6e-09 36.1 0.0 2.5e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS80437.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS80437.1 - 0.002 17.0 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS80437.1 - 0.0043 16.1 0.3 0.0072 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 ETS80437.1 - 0.0043 15.9 0.0 0.008 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS80437.1 - 0.012 14.6 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS80437.1 - 0.036 12.5 0.3 0.073 11.5 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 ETS80437.1 - 0.091 12.5 0.7 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 ETS80437.1 - 0.12 12.5 0.4 0.3 11.2 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF605 PF04652.11 ETS80438.1 - 7.9 5.7 11.8 9.2 5.5 8.2 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_S8 PF00410.14 ETS80439.1 - 6.7e-05 22.7 0.0 0.11 12.3 0.1 2.3 2 1 0 2 2 2 2 Ribosomal protein S8 SnoaL_4 PF13577.1 ETS80439.1 - 0.015 15.2 0.5 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 SnoaL-like domain Ank_2 PF12796.2 ETS80440.1 - 1.2e-51 173.0 0.0 3e-19 69.1 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80440.1 - 2.7e-36 121.5 0.2 9.9e-10 37.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 ETS80440.1 - 2.3e-34 118.3 9.4 2.3e-34 118.3 6.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 ETS80440.1 - 4.1e-30 103.6 3.3 1.7e-09 37.9 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS80440.1 - 1.4e-27 95.0 0.2 5.1e-08 32.9 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80440.1 - 1.7e-25 86.5 0.1 3.9e-09 35.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat SRPRB PF09439.5 ETS80441.1 - 4.4e-30 104.2 0.0 3.7e-29 101.2 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 ETS80441.1 - 5.6e-05 22.4 0.0 0.00036 19.8 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS80441.1 - 0.0003 20.7 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS80441.1 - 0.0024 17.8 0.2 0.0046 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 ETS80441.1 - 0.0061 16.0 0.2 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 ETS80441.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS80441.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 ETS80441.1 - 0.056 13.7 0.2 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 ETS80441.1 - 0.063 13.4 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.2 ETS80442.1 - 8.6e-18 65.0 1.1 1.1e-17 64.6 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80442.1 - 8e-07 28.9 0.3 9e-07 28.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS80442.1 - 0.00052 20.3 0.3 0.0012 19.0 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_8 PF06259.7 ETS80442.1 - 0.011 15.1 0.5 0.018 14.5 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 ETS80442.1 - 0.095 12.2 0.3 2.4 7.6 0.2 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 ETS80443.1 - 9.2e-30 104.1 0.0 1.1e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS80443.1 - 2e-29 102.6 0.6 2.4e-29 102.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS80443.1 - 2.3e-13 50.1 0.2 3.7e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS80443.1 - 8.4e-05 22.1 0.1 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS80443.1 - 0.00019 21.4 0.1 0.00038 20.5 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 ETS80443.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS80443.1 - 0.0023 16.7 0.1 0.0035 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_Gly3P_dh_N PF01210.18 ETS80443.1 - 0.0038 16.9 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RmlD_sub_bind PF04321.12 ETS80443.1 - 0.0047 15.8 0.1 0.39 9.5 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 ETS80443.1 - 0.0076 15.2 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 ETS80443.1 - 0.024 13.7 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 ETS80443.1 - 0.043 14.2 0.2 0.087 13.2 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 ETS80443.1 - 0.05 12.4 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 ETS80443.1 - 0.058 13.8 0.1 0.61 10.5 0.0 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 ETS80443.1 - 0.07 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding YjeF_N PF03853.10 ETS80443.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Phage_ASH PF10554.4 ETS80443.1 - 0.093 13.0 0.0 0.94 9.8 0.0 2.1 1 1 0 2 2 2 0 Ash protein family ApbA PF02558.11 ETS80443.1 - 0.099 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.10 ETS80443.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Fungal_trans_2 PF11951.3 ETS80444.1 - 9e-07 27.8 0.2 1.7e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 ETS80445.1 - 5e-40 137.3 10.4 6.5e-40 137.0 7.2 1.1 1 0 0 1 1 1 1 RTA1 like protein YqjK PF13997.1 ETS80445.1 - 0.19 11.9 0.1 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 YqjK-like protein Zn_clus PF00172.13 ETS80446.1 - 2.7e-09 36.7 9.0 5.4e-09 35.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS80446.1 - 0.00019 20.1 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 ETS80447.1 - 6.6e-26 90.2 2.8 9.8e-26 89.6 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS80447.1 - 7.2e-15 54.6 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS80447.1 - 0.0038 16.3 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS80447.1 - 0.17 11.4 0.3 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain LtrA PF06772.6 ETS80448.1 - 2.2e-13 49.8 24.3 2.2e-13 49.8 16.8 1.9 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Amidase PF01425.16 ETS80450.1 - 5.2e-59 200.2 0.0 6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF2185 PF09951.4 ETS80450.1 - 0.19 11.5 0.0 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) Metallophos PF00149.23 ETS80452.1 - 6.1e-11 42.0 4.8 9.4e-11 41.4 3.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_7 PF03441.9 ETS80453.1 - 5.4e-79 265.2 0.8 8e-79 264.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS80453.1 - 5.6e-39 133.5 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase AAA_2 PF07724.9 ETS80454.1 - 2e-46 157.9 0.0 5.5e-45 153.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 ETS80454.1 - 1.5e-27 96.3 0.3 5.1e-15 55.8 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 ETS80454.1 - 1.1e-24 86.0 0.6 4e-24 84.3 0.4 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 ETS80454.1 - 2.6e-16 60.1 13.0 1.8e-06 28.0 0.0 6.6 4 2 3 7 7 7 2 AAA ATPase domain AAA_5 PF07728.9 ETS80454.1 - 3.4e-16 59.2 0.0 2.2e-10 40.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS80454.1 - 7.9e-14 51.9 0.0 4.6e-05 23.5 0.0 4.0 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 ETS80454.1 - 2.5e-09 36.8 0.0 8.4e-06 25.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 ETS80454.1 - 1.9e-08 35.1 3.3 0.0089 16.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain Clp_N PF02861.15 ETS80454.1 - 2.1e-07 30.7 7.0 7.4e-06 25.8 0.1 4.2 4 0 0 4 4 3 1 Clp amino terminal domain AAA_18 PF13238.1 ETS80454.1 - 3.9e-07 30.4 0.0 0.026 14.8 0.0 3.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ETS80454.1 - 5.9e-07 29.0 0.0 0.025 13.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 ETS80454.1 - 1.1e-06 28.2 1.9 0.031 14.0 0.1 3.1 3 0 0 3 3 2 2 Part of AAA domain Arch_ATPase PF01637.13 ETS80454.1 - 3.7e-06 26.8 5.7 0.0079 15.9 0.0 5.0 5 1 1 6 6 5 1 Archaeal ATPase Mg_chelatase PF01078.16 ETS80454.1 - 1.3e-05 24.4 0.2 0.19 10.8 0.0 3.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 ETS80454.1 - 2.4e-05 24.3 0.0 0.26 11.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS80454.1 - 3.8e-05 23.6 0.0 0.19 11.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS80454.1 - 5.4e-05 22.2 1.1 0.0069 15.3 0.2 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 ETS80454.1 - 6.2e-05 23.1 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 ETS80454.1 - 0.00018 21.2 0.0 0.87 9.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 ETS80454.1 - 0.00018 21.0 0.0 1 8.9 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS80454.1 - 0.00021 20.7 0.1 1.4 8.2 0.0 3.6 3 1 0 4 4 3 2 AAA domain ResIII PF04851.10 ETS80454.1 - 0.00026 20.8 0.0 0.098 12.4 0.0 3.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 ETS80454.1 - 0.00064 20.0 0.4 1.1 9.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 ETS80454.1 - 0.00081 18.6 0.0 0.38 9.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS80454.1 - 0.00084 18.8 0.0 0.8 9.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 ETS80454.1 - 0.0013 18.3 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 ETS80454.1 - 0.0031 17.2 0.1 0.25 11.0 0.0 3.5 4 0 0 4 4 3 1 NTPase NACHT PF05729.7 ETS80454.1 - 0.004 16.8 0.0 0.36 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 ETS80454.1 - 0.0045 16.4 3.4 0.3 10.4 0.0 4.0 5 1 0 5 5 4 1 AAA-like domain Torsin PF06309.6 ETS80454.1 - 0.0075 16.1 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_21 PF13304.1 ETS80454.1 - 0.016 15.2 0.1 2.6 7.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.17 ETS80454.1 - 0.019 14.3 0.0 3.9 6.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 ETS80454.1 - 0.023 14.3 0.0 8.5 6.0 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 ETS80454.1 - 0.049 13.5 0.1 3.5 7.6 0.0 3.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 ETS80454.1 - 0.091 12.2 0.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 ETS80454.1 - 1.2 6.8 5.4 2.1 6.1 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 ETS80454.1 - 2 8.7 0.0 2 8.7 0.0 4.3 4 1 0 4 4 2 0 AAA domain Macoilin PF09726.4 ETS80454.1 - 2.5 6.2 9.9 4.1 5.5 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Mhr1 PF12829.2 ETS80455.1 - 7.1e-24 83.4 0.0 1.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination CbiN PF02553.10 ETS80455.1 - 0.096 12.7 0.2 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Cobalt transport protein component CbiN SRP72 PF08492.7 ETS80455.1 - 2.1 8.8 7.1 0.23 11.8 1.4 2.0 2 0 0 2 2 2 0 SRP72 RNA-binding domain 2OG-FeII_Oxy_3 PF13640.1 ETS80457.1 - 0.0077 16.7 0.1 0.029 14.8 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS80457.1 - 0.0088 16.3 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-X PF08320.7 ETS80458.1 - 2.4e-64 216.4 0.0 4.1e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 zf-C3HC4_3 PF13920.1 ETS80459.1 - 0.042 13.5 12.1 0.066 12.8 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 ETS80459.1 - 0.077 12.7 6.2 0.12 12.1 4.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4360 PF14273.1 ETS80461.1 - 9.5e-55 185.0 0.3 9.5e-55 185.0 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4360) DUF566 PF04484.7 ETS80461.1 - 4 6.8 19.4 5.5 6.4 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PAP1 PF08601.5 ETS80461.1 - 9.4 5.8 22.6 12 5.4 15.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF605 PF04652.11 ETS80461.1 - 9.8 5.4 21.2 12 5.1 14.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF2733 PF10813.3 ETS80462.1 - 2.7 7.6 5.1 2.9 7.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DUF2834 PF11196.3 ETS80463.1 - 0.011 15.9 1.8 3 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) AT_hook PF02178.14 ETS80463.1 - 0.45 10.3 12.3 0.73 9.6 1.7 2.6 2 0 0 2 2 2 0 AT hook motif Arf PF00025.16 ETS80464.1 - 2.3e-38 131.1 0.0 2.6e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 ETS80464.1 - 4.2e-10 38.8 0.0 8.7e-06 24.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 ETS80464.1 - 5.6e-08 32.3 0.0 0.00093 18.6 0.0 2.3 2 0 0 2 2 2 2 Ras family SRPRB PF09439.5 ETS80464.1 - 1.3e-06 27.7 0.0 9e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS80464.1 - 1.4e-06 27.6 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS80464.1 - 0.00013 21.4 0.0 0.00044 19.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 ETS80464.1 - 0.00015 22.2 0.0 0.00074 20.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS80464.1 - 0.037 13.9 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNase_PH PF01138.16 ETS80465.1 - 9.2e-23 81.0 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS80465.1 - 5.5e-10 39.0 0.0 9.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 ETS80466.1 - 2.9e-82 276.0 18.9 3.6e-82 275.7 13.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 ETS80466.1 - 0.26 11.3 14.5 0.45 10.5 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1509 PF07420.6 ETS80466.1 - 0.4 9.9 6.8 0.51 9.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) CDC45 PF02724.9 ETS80466.1 - 0.65 7.9 19.8 0.84 7.5 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 ETS80466.1 - 0.74 9.0 23.3 1.1 8.5 16.2 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS80466.1 - 1 7.2 23.9 1.2 7.0 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETS80466.1 - 1.3 7.4 20.7 1.8 6.9 14.4 1.2 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 ETS80466.1 - 2.7 5.9 14.6 3.6 5.5 10.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.12 ETS80466.1 - 3.8 6.2 5.1 5.1 5.8 3.5 1.1 1 0 0 1 1 1 0 Presenilin DUF1510 PF07423.6 ETS80466.1 - 4 6.7 16.8 6.1 6.1 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TPD52 PF04201.10 ETS80466.1 - 6.6 6.4 8.6 0.68 9.6 3.0 1.5 2 0 0 2 2 2 0 Tumour protein D52 family ATP-synt_E PF05680.7 ETS80466.1 - 8.6 6.3 8.3 2 8.4 3.3 1.8 2 0 0 2 2 2 0 ATP synthase E chain EBP PF05241.7 ETS80467.1 - 9.4e-52 174.8 7.4 1.4e-51 174.2 5.1 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 ETS80467.1 - 1.5 8.5 10.2 2.2 8.0 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) PBP PF01161.15 ETS80468.1 - 1.9e-22 79.7 0.0 2.3e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 ETS80469.1 - 1.5e-07 31.2 10.3 3.5e-07 30.0 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS80469.1 - 4.2e-05 22.5 0.1 0.0001 21.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_75 PF07335.6 ETS80470.1 - 4.2e-46 156.6 0.2 6.4e-46 156.0 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SpdB PF05122.8 ETS80470.1 - 0.38 10.8 1.9 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Mobile element transfer protein Kri1 PF05178.7 ETS80471.1 - 2.3e-25 88.8 27.1 2.3e-25 88.8 18.8 5.3 3 1 1 4 4 4 1 KRI1-like family Kri1_C PF12936.2 ETS80471.1 - 1.1e-23 82.9 0.1 1.1e-23 82.9 0.1 4.0 3 1 1 4 4 4 1 KRI1-like family C-terminal Ras PF00071.17 ETS80472.1 - 1.8e-58 196.4 0.0 2.1e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS80472.1 - 1.7e-20 73.7 0.0 3.3e-20 72.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS80472.1 - 2.3e-16 59.5 0.0 2.7e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS80472.1 - 8.5e-09 34.8 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS80472.1 - 3.1e-08 33.2 0.0 7.4e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS80472.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS80472.1 - 0.0039 17.2 0.0 0.0058 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS80472.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.22 ETS80473.1 - 1.1e-30 106.8 0.0 2e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 ETS80473.1 - 6.9e-19 67.3 0.0 1.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Fungal_trans PF04082.13 ETS80474.1 - 2.2e-13 49.6 2.2 7.3e-13 47.9 1.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80474.1 - 9.3e-09 35.0 12.1 1.6e-08 34.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.6 ETS80475.1 - 1.1e-20 73.0 0.5 2.2e-20 72.0 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 ETS80475.1 - 3.7e-08 32.8 0.9 7.2e-08 31.9 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Rhodanese PF00581.15 ETS80476.1 - 9.6e-09 35.5 0.0 3.5e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 ETS80476.1 - 1.3e-07 31.0 0.1 3.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain Peptidase_C14 PF00656.17 ETS80476.1 - 0.004 16.8 0.0 0.02 14.6 0.0 1.6 1 1 1 2 2 2 1 Caspase domain DUF3632 PF12311.3 ETS80477.1 - 2.5e-16 60.0 0.1 4.6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.17 ETS80478.1 - 4.2e-24 84.9 0.0 1e-23 83.6 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 FGGY_C PF02782.11 ETS80479.1 - 2e-27 96.0 0.0 3.2e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 ETS80479.1 - 6.4e-24 84.6 0.0 2.3e-14 53.3 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 ETS80480.1 - 4.1e-54 183.5 0.2 5.1e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family SIR2 PF02146.12 ETS80481.1 - 3.7e-33 114.7 0.0 6.4e-33 113.9 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Glyco_tran_WbsX PF14307.1 ETS80481.1 - 0.046 12.8 0.3 0.068 12.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX DUF1654 PF07867.6 ETS80482.1 - 0.073 12.4 2.6 0.078 12.3 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) Peptidase_C50 PF03568.12 ETS80483.1 - 2.4e-109 365.5 0.0 4.2e-109 364.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 ETS80483.1 - 6.9e-12 45.1 14.3 8.5e-06 25.6 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.4 ETS80483.1 - 1.1e-05 24.8 4.5 0.52 9.6 0.1 3.7 3 0 0 3 3 3 3 26S proteasome subunit RPN7 TPR_2 PF07719.12 ETS80483.1 - 1.5e-05 24.5 11.4 2.8 8.0 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80483.1 - 0.0004 19.9 7.6 10 6.1 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS80483.1 - 0.0067 16.0 6.5 15 5.3 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80483.1 - 0.02 15.4 17.7 9.4 7.1 1.0 8.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80483.1 - 0.03 14.1 5.1 8.9 6.3 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS80483.1 - 0.031 14.2 6.5 5.8 6.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80483.1 - 0.22 12.0 9.9 9.2 6.9 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 ETS80484.1 - 2e-26 92.4 0.0 3.3e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80484.1 - 3e-09 36.6 10.1 4.7e-09 35.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 ETS80486.1 - 2.1e-15 56.3 5.6 0.01 15.7 0.0 4.9 5 0 0 5 5 5 4 LysM domain HTH_28 PF13518.1 ETS80486.1 - 0.11 12.4 0.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_hydro_18 PF00704.23 ETS80487.1 - 1.1e-77 261.7 2.7 1.7e-77 261.2 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS80487.1 - 1.9e-07 30.9 19.9 1.9e-07 30.9 13.8 4.1 4 0 0 4 4 4 1 Chitin recognition protein SGT1 PF07093.6 ETS80490.1 - 0.2 9.9 3.8 0.26 9.6 2.7 1.1 1 0 0 1 1 1 0 SGT1 protein RAP1 PF07218.6 ETS80490.1 - 0.84 7.6 7.0 1.2 7.1 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med11 PF10280.4 ETS80491.1 - 0.054 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Mediator complex protein SeqA PF03925.8 ETS80491.1 - 0.089 12.4 1.0 0.17 11.5 0.7 1.4 1 0 0 1 1 1 0 SeqA protein Striatin PF08232.7 ETS80491.1 - 0.11 12.8 3.3 0.27 11.5 2.3 1.6 1 0 0 1 1 1 0 Striatin family DUF4407 PF14362.1 ETS80491.1 - 0.66 8.8 7.4 1.2 7.9 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 ETS80492.1 - 7.1e-16 57.6 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS80492.1 - 7.7e-12 45.0 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS80492.1 - 3.5e-08 33.1 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.4 ETS80493.1 - 4.7e-41 139.0 4.5 2.2e-35 120.8 0.7 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.8 ETS80494.1 - 1.5e-43 147.8 0.0 1.7e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 ETS80494.1 - 0.00015 21.5 0.0 0.1 12.3 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family Histone PF00125.19 ETS80495.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 ETS80495.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 ETS80495.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETS80495.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 ETS80495.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 ETS80495.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TPR_11 PF13414.1 ETS80496.1 - 3.3e-46 154.8 35.3 3.4e-13 49.0 3.6 7.6 6 2 2 8 8 7 7 TPR repeat TPR_2 PF07719.12 ETS80496.1 - 1.2e-41 137.2 38.3 7.5e-06 25.4 0.1 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETS80496.1 - 8.9e-41 135.8 33.1 2.3e-07 30.1 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 ETS80496.1 - 3.6e-31 107.1 32.3 6.1e-22 77.5 0.2 5.6 6 0 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 ETS80496.1 - 7.4e-28 96.3 31.2 3.3e-06 26.9 0.4 7.8 4 3 6 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80496.1 - 7.4e-28 94.2 21.8 8.6e-06 25.1 0.2 10.4 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80496.1 - 1.3e-24 84.4 20.3 0.0027 18.1 0.6 10.6 5 2 6 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS80496.1 - 1e-23 83.4 15.6 2.1e-08 34.3 3.3 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80496.1 - 1.9e-23 82.5 34.2 6.9e-07 29.7 1.2 8.7 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETS80496.1 - 1.2e-22 78.1 22.5 0.0044 17.1 0.2 10.3 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80496.1 - 5.2e-19 66.4 19.5 0.0036 16.9 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80496.1 - 1.8e-14 53.1 20.1 0.051 14.0 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS80496.1 - 3.4e-08 33.2 12.8 0.00073 19.3 0.4 6.1 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 ETS80496.1 - 2e-06 27.0 10.8 0.0079 15.2 0.9 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 ETS80496.1 - 3.6e-05 23.7 3.1 0.057 13.8 0.4 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 ETS80496.1 - 0.00064 19.2 6.7 3.5 7.0 2.7 4.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.1 ETS80496.1 - 0.0023 17.9 4.0 0.26 11.4 0.5 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 ETS80496.1 - 0.008 14.9 4.9 0.64 8.6 0.6 3.5 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 ChAPs PF09295.5 ETS80496.1 - 0.092 11.4 1.1 2.9 6.5 0.1 3.4 3 1 2 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 ETS80496.1 - 0.12 12.2 12.5 0.62 9.9 0.1 5.3 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat APP_E2 PF12925.2 ETS80496.1 - 1.6 8.2 6.9 20 4.6 0.8 3.9 3 2 1 4 4 4 0 E2 domain of amyloid precursor protein DUF788 PF05620.6 ETS80497.1 - 2.4e-42 144.6 0.0 2.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) FA_desaturase PF00487.19 ETS80497.1 - 0.049 13.0 1.3 0.061 12.7 0.9 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3605 PF12239.3 ETS80498.1 - 1.7e-56 190.4 0.0 2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 ETS80499.1 - 1.1e-26 92.8 0.0 1.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETS80499.1 - 1.3e-26 93.2 0.0 2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETS80499.1 - 1.8e-05 24.6 0.0 0.0059 16.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS80499.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Abhydrolase_3 PF07859.8 ETS80500.1 - 9.2e-21 74.3 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS80500.1 - 1.2e-18 66.9 0.0 1.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 ETS80500.1 - 0.0062 15.2 0.3 0.14 10.7 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family CBFD_NFYB_HMF PF00808.18 ETS80501.1 - 1.8e-13 50.3 2.3 3e-13 49.6 1.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS80501.1 - 5.9e-07 29.5 0.2 9.1e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FlaC_arch PF05377.6 ETS80502.1 - 0.0021 17.8 1.9 3.3 7.6 0.1 3.9 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 ETS80502.1 - 0.083 12.6 2.9 0.95 9.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 ETS80502.1 - 0.083 12.0 20.1 8 5.5 9.8 3.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 ETS80502.1 - 0.099 12.4 2.2 13 5.5 0.3 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) LPP PF04728.8 ETS80502.1 - 0.61 9.9 4.9 0.22 11.3 0.7 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.7 ETS80502.1 - 0.83 9.4 11.9 1.9 8.2 1.5 3.5 2 1 1 3 3 3 0 Laminin Domain II MCPsignal PF00015.16 ETS80502.1 - 1.3 8.5 14.9 5.5 6.4 0.6 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE_assoc PF09335.6 ETS80503.1 - 2.1e-17 63.4 7.0 2.1e-17 63.4 4.9 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1469 PF07332.6 ETS80503.1 - 0.0042 16.8 2.6 0.054 13.2 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) DUF3816 PF12822.2 ETS80503.1 - 2.4 8.0 21.1 0.26 11.1 9.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) MRJP PF03022.11 ETS80504.1 - 1.8e-18 66.7 0.0 2.3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein Ribosomal_S13 PF00416.17 ETS80506.1 - 5.8e-41 139.2 1.5 7e-41 139.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 ETS80506.1 - 0.0019 16.8 0.0 0.0028 16.2 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 ETS80506.1 - 0.083 12.9 0.4 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF2746 PF10874.3 ETS80506.1 - 0.1 12.7 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) SBDS_C PF09377.5 ETS80507.1 - 8.8e-53 177.2 0.1 1.6e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 ETS80507.1 - 1.5e-29 101.6 0.3 2.4e-29 100.9 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 ETS80508.1 - 1.7e-131 439.1 2.4 2.2e-131 438.8 1.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 ETS80508.1 - 5.8e-06 26.4 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 ETS80508.1 - 0.0074 16.1 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cas1_AcylT PF07779.7 ETS80509.1 - 3.1e-87 293.1 25.0 9.9e-66 222.1 13.2 3.6 2 1 1 3 3 3 3 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 ETS80509.1 - 7.9e-22 78.3 0.0 1.2e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GFA PF04828.9 ETS80510.1 - 5.7e-19 67.8 1.3 7.6e-19 67.4 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Oxysterol_BP PF01237.13 ETS80514.1 - 0.29 9.5 2.7 0.45 8.9 1.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein CcoS PF03597.10 ETS80514.1 - 4 6.9 6.1 6.6 6.2 4.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF1764 PF08576.5 ETS80514.1 - 7.3 7.4 10.2 1.2 9.9 3.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L22 PF00237.14 ETS80516.1 - 4.1e-34 116.6 0.1 5.5e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 ETS80517.1 - 9.1e-105 348.6 0.0 1.1e-104 348.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 ETS80517.1 - 8.5e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 ETS80517.1 - 0.03 13.8 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 ETS80517.1 - 0.067 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Dicty_CAR PF05462.6 ETS80519.1 - 2.4e-16 59.5 7.1 2.4e-16 59.5 4.9 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 ETS80519.1 - 7.6e-10 38.6 9.2 1.4e-09 37.8 6.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 ETS80519.1 - 8.6e-08 31.6 0.0 1.4e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 ETS80519.1 - 0.0023 17.1 3.0 0.0034 16.5 2.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.12 ETS80519.1 - 0.42 9.3 10.1 0.13 11.0 1.0 2.3 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Peroxidase_2 PF01328.12 ETS80520.1 - 2.2e-32 112.0 0.0 2.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Methyltransf_11 PF08241.7 ETS80521.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.15 ETS80522.1 - 4.2e-23 81.4 34.1 2.1e-22 79.1 22.7 2.4 2 1 0 2 2 2 1 Permease family CASP_C PF08172.7 ETS80523.1 - 9.2e-93 309.8 0.1 9.2e-93 309.8 0.1 3.3 3 1 0 3 3 3 1 CASP C terminal ADIP PF11559.3 ETS80523.1 - 0.012 15.4 7.9 0.012 15.4 5.5 6.6 4 1 3 7 7 7 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 ETS80523.1 - 0.37 10.5 55.4 0.26 11.0 0.3 5.1 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 ETS80523.1 - 0.45 10.9 0.0 0.45 10.9 0.0 5.3 6 0 0 6 6 6 0 SlyX FemAB PF02388.11 ETS80523.1 - 0.48 9.0 16.3 1.6 7.3 0.0 3.9 3 1 0 3 3 3 0 FemAB family Tropomyosin_1 PF12718.2 ETS80523.1 - 0.49 10.2 56.8 0.45 10.3 3.3 5.4 3 1 1 5 5 5 0 Tropomyosin like DUF1192 PF06698.6 ETS80523.1 - 0.7 9.7 12.3 0.061 13.1 0.6 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.4 ETS80523.1 - 0.86 9.4 56.0 0.03 14.1 0.7 5.7 4 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETS80523.1 - 3.2 7.3 57.8 0.3 10.6 0.7 5.0 4 1 1 5 5 5 0 IncA protein Nup54 PF13874.1 ETS80523.1 - 4 7.1 29.4 0.88 9.2 1.5 5.0 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 Hemerythrin PF01814.18 ETS80523.1 - 4.5 7.4 10.5 18 5.4 0.4 4.6 4 1 0 4 4 4 0 Hemerythrin HHE cation binding domain DUF3455 PF11937.3 ETS80524.1 - 8.8e-44 149.5 0.3 1.3e-43 149.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Peptidase_C12 PF01088.16 ETS80525.1 - 1.7e-73 246.3 0.0 4.1e-73 245.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Vps39_2 PF10367.4 ETS80526.1 - 4.9e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 ETS80526.1 - 0.0037 17.2 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 DUF2360 PF10152.4 ETS80526.1 - 0.74 10.0 3.4 11 6.2 2.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 ETS80527.1 - 4.4e-54 178.5 31.4 1.3e-11 43.9 0.0 12.6 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 ETS80527.1 - 1.5e-27 95.6 0.0 2.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 ETS80527.1 - 3e-07 30.3 1.0 0.1 12.2 0.1 5.3 5 2 2 8 8 8 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 ETS80527.1 - 0.00074 17.4 0.0 0.041 11.7 0.0 2.5 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 ETS80527.1 - 0.0036 16.4 0.1 8.9 5.3 0.0 3.9 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.6 ETS80527.1 - 0.07 12.7 0.3 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Cytochrom_D1 PF02239.11 ETS80527.1 - 0.08 11.2 0.0 6.1 5.0 0.0 3.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain BCS1_N PF08740.6 ETS80528.1 - 1.1e-36 126.2 0.2 1.6e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 ETS80528.1 - 1.7e-16 60.6 0.0 4.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS80528.1 - 0.00017 22.3 0.4 0.0016 19.2 0.0 2.7 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS80528.1 - 0.0006 18.9 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS80528.1 - 0.0011 18.3 0.0 0.003 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS80528.1 - 0.017 14.8 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 ETS80528.1 - 0.035 13.6 1.8 0.099 12.2 0.3 2.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 ETS80528.1 - 0.046 14.0 0.1 0.24 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS80528.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 ETS80528.1 - 0.074 13.1 0.1 2.5 8.2 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.1 ETS80528.1 - 0.38 10.7 2.6 0.73 9.7 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain ADH_zinc_N PF00107.21 ETS80529.1 - 1.1e-08 34.6 0.1 2e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS80529.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 ETS80530.1 - 2.6e-17 62.3 0.1 8.5e-09 34.2 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 ETS80531.1 - 1.6e-31 109.0 0.0 3.4e-29 101.5 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore complex component FAD_binding_3 PF01494.14 ETS80532.1 - 3.5e-61 207.2 0.2 4.3e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS80532.1 - 9.1e-07 28.0 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS80532.1 - 3e-05 23.9 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS80532.1 - 9.4e-05 22.3 0.1 0.00029 20.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS80532.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS80532.1 - 0.00066 19.7 0.1 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.7 ETS80532.1 - 0.00075 19.1 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 ETS80532.1 - 0.00094 17.7 0.1 0.0015 17.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 ETS80532.1 - 0.0027 16.8 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS80532.1 - 0.006 15.7 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 ETS80532.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 ETS80532.1 - 0.081 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS80532.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 ETS80532.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding SnoaL_2 PF12680.2 ETS80533.1 - 0.031 14.6 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Ribosomal_L36e PF01158.13 ETS80533.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e SPC22 PF04573.7 ETS80534.1 - 5.8e-36 123.3 0.6 7e-26 90.5 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit MCM PF00493.18 ETS80535.1 - 2e-141 470.6 0.1 2.7e-141 470.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS80535.1 - 1.8e-15 57.5 0.7 4.5e-15 56.2 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS80535.1 - 8.1e-07 28.4 0.0 0.00017 20.8 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETS80535.1 - 4.2e-05 23.2 0.0 9.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 ETS80535.1 - 0.00038 20.0 0.1 0.0024 17.4 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS80535.1 - 0.038 13.4 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 ETS80535.1 - 0.081 13.3 1.0 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Vps54 PF07928.7 ETS80536.1 - 5.3e-45 152.8 0.1 3e-44 150.4 0.0 2.4 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 ETS80536.1 - 5.9e-08 31.9 1.8 5.9e-08 31.9 1.2 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 ETS80536.1 - 0.0034 17.0 1.9 0.031 13.9 1.0 2.8 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 ETS80536.1 - 0.015 15.1 1.5 0.1 12.4 1.3 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 ETS80536.1 - 0.19 10.7 2.5 0.39 9.7 1.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3490 PF11995.3 ETS80536.1 - 0.43 10.1 4.6 0.52 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) DUF904 PF06005.7 ETS80536.1 - 3.9 7.8 12.3 0.12 12.6 3.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) MTHFR PF02219.12 ETS80537.1 - 4.2e-103 344.3 0.0 6.1e-103 343.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.16 ETS80538.1 - 6e-12 45.1 0.0 5.4e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Tannase PF07519.6 ETS80538.1 - 0.24 10.0 0.1 0.6 8.7 0.0 1.5 2 0 0 2 2 2 0 Tannase and feruloyl esterase PQ-loop PF04193.9 ETS80540.1 - 9.7e-19 66.6 4.2 1.8e-12 46.6 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat WSC PF01822.14 ETS80541.1 - 1.9e-71 235.9 68.2 1.2e-18 66.8 8.7 5.2 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.18 ETS80541.1 - 9.6e-20 71.0 0.1 2.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.20 ETS80542.1 - 1.3e-69 234.2 0.0 1.9e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80542.1 - 1.7e-49 168.2 0.0 2.3e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80542.1 - 1.6e-08 33.8 0.0 3.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Transglut_core PF01841.14 ETS80543.1 - 5.3e-11 42.7 0.4 5.3e-11 42.7 0.3 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 ETS80543.1 - 1.9e-08 33.6 0.3 5.8e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS80543.1 - 1.5e-07 30.7 0.1 1.5e-07 30.7 0.0 2.9 4 0 0 4 4 4 1 SH3 domain SH3_9 PF14604.1 ETS80543.1 - 1.3e-05 24.7 1.6 1.4e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Sugar_tr PF00083.19 ETS80544.1 - 7.6e-76 255.4 24.3 8.7e-76 255.2 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80544.1 - 1.3e-15 56.9 22.7 1.3e-15 56.9 15.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4190 PF13828.1 ETS80544.1 - 0.032 13.7 1.8 0.049 13.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) HpcH_HpaI PF03328.9 ETS80545.1 - 2.2e-26 92.1 0.0 2.7e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DIT1_PvcA PF05141.7 ETS80546.1 - 2e-70 237.2 0.0 2.7e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.7 ETS80547.1 - 4.4e-75 252.5 0.0 5.5e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein NAD_binding_4 PF07993.7 ETS80548.1 - 3.7e-36 124.3 0.0 5.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS80548.1 - 4.9e-23 81.1 0.0 8.2e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 ETS80548.1 - 5.7e-12 45.5 0.0 9.5e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS80548.1 - 0.00045 20.2 0.0 0.0048 16.9 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding PP-binding PF00550.20 ETS80548.1 - 0.0023 18.1 0.1 0.005 17.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 ETS80548.1 - 0.0094 14.6 0.0 0.024 13.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS80548.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETS80548.1 - 0.25 10.1 0.0 18 4.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DUF4066 PF13278.1 ETS80549.1 - 2.8e-22 78.7 0.1 3.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS80549.1 - 1.8e-10 40.4 0.0 2.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pyr_redox_3 PF13738.1 ETS80551.1 - 2.9e-24 86.2 0.0 8.3e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS80551.1 - 3.9e-17 61.6 0.0 1.1e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS80551.1 - 1.4e-12 47.9 0.0 7.8e-08 32.4 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS80551.1 - 6e-11 41.8 1.0 4.2e-09 35.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS80551.1 - 5.2e-08 32.7 0.0 0.00043 20.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS80551.1 - 6.6e-08 32.8 1.5 5.3e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS80551.1 - 1.1e-07 31.2 0.0 0.00077 18.6 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 ETS80551.1 - 6.3e-07 29.5 0.2 0.00041 20.4 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 ETS80551.1 - 1.2e-06 27.6 0.8 0.057 12.2 0.3 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 ETS80551.1 - 2.5e-05 23.3 0.0 0.019 13.8 0.0 3.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS80551.1 - 5.2e-05 22.4 0.1 0.24 10.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 ETS80551.1 - 6.8e-05 21.8 1.5 0.0021 16.9 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS80551.1 - 9.5e-05 21.4 0.0 0.074 11.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 ETS80551.1 - 0.00031 19.9 0.0 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 ETS80551.1 - 0.00043 19.7 0.6 0.0099 15.3 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 ETS80551.1 - 0.00079 19.1 0.4 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 ETS80551.1 - 0.0016 17.7 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 ETS80551.1 - 0.0017 16.8 0.6 0.18 10.2 0.3 2.9 3 0 0 3 3 3 1 HI0933-like protein SnoaL_2 PF12680.2 ETS80551.1 - 0.002 18.5 0.1 0.015 15.7 0.0 2.5 3 0 0 3 3 2 1 SnoaL-like domain NAD_Gly3P_dh_N PF01210.18 ETS80551.1 - 0.0022 17.7 0.7 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 ETS80551.1 - 0.0028 17.8 0.6 0.022 15.0 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 ETS80551.1 - 0.015 15.3 0.1 9 6.3 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain DUF4147 PF13660.1 ETS80551.1 - 0.049 12.7 0.0 2.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) XdhC_C PF13478.1 ETS80551.1 - 0.069 13.4 0.0 19 5.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.1 ETS80551.1 - 0.11 12.3 0.9 7.3 6.3 0.3 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 ETS80551.1 - 0.11 12.5 0.0 3.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ThiF PF00899.16 ETS80551.1 - 0.21 11.4 0.6 7.2 6.4 0.1 2.4 2 0 0 2 2 2 0 ThiF family Amidase PF01425.16 ETS80552.1 - 1.4e-37 129.6 4.6 3.1e-36 125.1 1.6 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_43 PF04616.9 ETS80553.1 - 1.3e-27 96.6 0.1 2.4e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Adeno_E3_CR2 PF02439.10 ETS80554.1 - 0.28 10.7 1.9 0.81 9.2 1.3 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PA14_2 PF10528.4 ETS80555.1 - 1.1e-22 80.0 0.4 1.1e-22 80.0 0.3 2.3 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.7 ETS80555.1 - 2.3e-06 27.3 0.2 8.8e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 PA14 domain GST_N_3 PF13417.1 ETS80556.1 - 1.1e-09 38.4 0.0 2.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS80556.1 - 0.0018 18.1 0.0 0.0049 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS80556.1 - 0.0066 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS80556.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.17 ETS80558.1 - 9.7e-63 212.0 0.0 1.1e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Asn_synthase PF00733.16 ETS80558.1 - 0.0088 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ABC_tran PF00005.22 ETS80559.1 - 2.2e-15 57.1 0.1 1.9e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS80559.1 - 7.9e-10 39.1 0.6 0.00042 20.3 0.3 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 ETS80559.1 - 0.00014 21.1 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS80559.1 - 0.0004 19.8 0.0 0.00074 19.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 ETS80559.1 - 0.00074 17.0 0.3 0.00096 16.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.14 ETS80559.1 - 0.0062 15.7 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS80559.1 - 0.0083 16.1 0.2 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 ETS80559.1 - 0.012 15.1 0.1 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 ETS80559.1 - 0.013 15.8 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS80559.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 ETS80559.1 - 0.015 14.7 0.1 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 ETS80559.1 - 0.017 15.9 0.8 0.045 14.5 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS80559.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS80559.1 - 0.023 14.6 0.6 0.041 13.8 0.4 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 ETS80559.1 - 0.055 12.7 0.3 0.17 11.1 0.2 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family DUF258 PF03193.11 ETS80559.1 - 0.057 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 ETS80559.1 - 0.059 12.8 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 ETS80559.1 - 0.073 13.2 0.1 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS80559.1 - 0.093 12.6 0.1 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS80559.1 - 0.12 12.5 0.6 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 ETS80559.1 - 0.14 10.6 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETS80559.1 - 0.15 11.7 0.2 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain CENP-I PF07778.6 ETS80560.1 - 2.1e-107 359.4 0.0 3.1e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.19 ETS80561.1 - 1e-05 25.4 0.0 8.6e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS80561.1 - 0.0026 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS80561.1 - 0.018 15.1 0.0 0.29 11.2 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Prenyltrans PF00432.16 ETS80561.1 - 0.019 14.5 0.1 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Acetyltransf_9 PF13527.1 ETS80561.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3384 PF11864.3 ETS80562.1 - 2.5e-90 303.2 0.0 4.9e-90 302.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 ETS80562.1 - 2e-56 190.3 0.0 4.1e-56 189.3 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 ETS80562.1 - 1.1e-36 126.6 1.0 5.7e-31 107.8 0.1 3.4 3 0 0 3 3 3 3 Tuberin CAS_CSE1 PF03378.10 ETS80563.1 - 3.9e-163 542.7 0.0 7.7e-163 541.8 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 ETS80563.1 - 1.3e-150 501.1 5.0 2.3e-150 500.2 3.3 1.5 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 ETS80563.1 - 1.5e-12 47.2 0.4 1.3e-11 44.2 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 ETS80563.1 - 0.01 15.7 7.7 0.05 13.5 0.0 4.6 6 0 0 6 6 6 0 Exportin 1-like protein Peptidase_S10 PF00450.17 ETS80564.1 - 2.2e-84 284.0 2.9 2.9e-84 283.6 2.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Apc3 PF12895.2 ETS80566.1 - 9e-32 109.0 12.2 1.2e-22 79.8 0.1 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 ETS80566.1 - 7.2e-31 104.5 7.2 0.0001 21.7 0.3 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80566.1 - 2.6e-29 98.7 23.8 0.00037 20.1 0.1 10.8 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80566.1 - 5.8e-29 99.5 21.8 5.7e-10 38.6 0.3 7.5 6 1 1 7 7 7 6 TPR repeat TPR_12 PF13424.1 ETS80566.1 - 8.4e-23 80.1 15.5 1.1e-08 34.8 0.1 8.6 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 ETS80566.1 - 4.5e-22 78.1 12.8 0.00028 21.1 0.1 8.1 5 3 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80566.1 - 1.2e-17 64.0 22.4 1.4e-07 31.9 0.7 7.9 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80566.1 - 6.3e-17 60.5 22.0 0.012 16.1 0.7 9.9 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80566.1 - 1.6e-16 58.7 3.5 0.016 14.9 0.1 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETS80566.1 - 1.1e-13 50.5 6.5 0.0031 17.3 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80566.1 - 1.5e-09 36.9 14.3 1.1 9.2 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80566.1 - 8.1e-09 35.3 10.8 1.5 9.4 0.1 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 ETS80566.1 - 7.3e-07 28.9 13.0 0.00053 19.7 0.2 5.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS80566.1 - 7.5e-06 25.7 3.4 12 6.4 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.1 ETS80566.1 - 0.00078 18.5 13.0 0.19 10.7 0.5 4.8 4 2 3 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 ETS80566.1 - 0.0012 18.7 0.1 2.6 8.2 0.0 5.0 5 0 0 5 5 5 1 PPR repeat TPR_4 PF07721.9 ETS80566.1 - 0.04 14.3 8.7 1.1 9.8 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETS80566.1 - 0.062 13.2 6.8 20 5.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS80566.1 - 0.41 10.7 7.8 2.4 8.3 0.1 4.1 5 1 0 5 5 3 0 Tetratricopeptide repeat DUF572 PF04502.8 ETS80567.1 - 1.9e-71 240.9 9.9 3e-71 240.3 6.8 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 ETS80567.1 - 0.007 15.6 1.4 0.007 15.6 1.0 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding Nop14 PF04147.7 ETS80567.1 - 0.26 9.1 11.9 0.31 8.8 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family FimP PF09766.4 ETS80567.1 - 1.4 7.9 5.5 1.3 7.9 3.4 1.3 1 1 0 1 1 1 0 Fms-interacting protein Metal_resist PF13801.1 ETS80567.1 - 3.9 7.4 21.5 5 7.1 3.2 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Spc97_Spc98 PF04130.8 ETS80568.1 - 8.7e-69 232.2 2.6 2e-68 231.0 1.8 1.6 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 ETS80568.1 - 0.00013 20.2 0.1 0.00024 19.3 0.1 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 ETS80569.1 - 1.2e-135 451.7 9.7 1.4e-135 451.4 6.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 ETS80570.1 - 4.3e-31 105.6 8.8 1.3e-07 31.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETS80570.1 - 0.00046 19.9 0.0 4 7.2 0.0 3.8 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 ETS80570.1 - 0.11 10.6 1.4 2.7 6.0 0.3 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Pet127 PF08634.5 ETS80571.1 - 8.2e-122 405.6 1.4 1.3e-121 404.9 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Pkinase PF00069.20 ETS80572.1 - 1.2e-11 44.3 0.0 2.7e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80572.1 - 2.7e-09 36.5 0.0 5.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_U35 PF04586.12 ETS80573.1 - 8.9e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Caudovirus prohead protease DUF1649 PF07855.7 ETS80574.1 - 7.6e-61 204.5 0.0 8.9e-61 204.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 ETS80574.1 - 0.022 14.3 1.9 0.053 13.1 1.3 1.6 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Peroxin-3 PF04882.7 ETS80575.1 - 7.3e-144 479.6 0.3 8.4e-144 479.4 0.2 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.7 ETS80576.1 - 1.7e-21 76.4 0.0 2.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 ETS80576.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF3682 PF12446.3 ETS80577.1 - 0.0037 17.5 2.9 0.0043 17.3 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) Pkinase PF00069.20 ETS80578.1 - 2e-59 200.8 0.0 4.4e-59 199.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80578.1 - 2.5e-34 118.5 0.0 4.4e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80578.1 - 2.3e-09 36.6 0.0 1e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETS80578.1 - 0.00042 20.1 0.2 0.00097 18.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DOT1 PF08123.8 ETS80579.1 - 6.4e-66 221.5 0.0 1e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 ETS80579.1 - 0.0006 19.4 0.1 0.0047 16.5 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS80579.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80579.1 - 0.0082 16.7 0.0 0.039 14.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 ETS80580.1 - 7.4e-40 136.8 19.2 8.3e-40 136.6 13.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 ETS80580.1 - 0.0043 16.5 14.2 0.0097 15.4 9.9 1.5 1 1 0 1 1 1 1 Intermediate filament protein AAA_13 PF13166.1 ETS80580.1 - 0.011 14.2 6.5 0.011 14.1 4.0 1.3 1 1 0 1 1 1 0 AAA domain CCDC144C PF14915.1 ETS80580.1 - 0.015 14.2 14.3 0.21 10.4 10.0 1.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region DUF4164 PF13747.1 ETS80580.1 - 0.022 14.8 19.6 0.094 12.8 1.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.16 ETS80580.1 - 0.083 12.8 15.4 1.3 8.9 0.1 4.1 2 1 1 3 3 3 0 bZIP transcription factor DUF4485 PF14846.1 ETS80580.1 - 0.1 12.3 1.0 0.26 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) GAS PF13851.1 ETS80580.1 - 0.26 10.4 16.1 0.35 10.0 1.0 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding KIAA1430 PF13879.1 ETS80580.1 - 0.45 10.9 7.7 0.28 11.6 3.6 1.9 1 1 1 2 2 2 0 KIAA1430 homologue DUF4163 PF13739.1 ETS80580.1 - 0.85 10.4 5.1 9 7.1 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4163) Reo_sigmaC PF04582.7 ETS80580.1 - 0.91 8.6 3.8 1.2 8.2 2.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fez1 PF06818.10 ETS80580.1 - 1.4 8.8 17.2 0.41 10.6 7.3 2.3 1 1 1 2 2 2 0 Fez1 APG6 PF04111.7 ETS80580.1 - 8.3 5.3 16.0 4.3 6.3 8.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Cluap1 PF10234.4 ETS80580.1 - 9.7 5.2 14.6 2.8 7.0 0.1 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 p450 PF00067.17 ETS80581.1 - 2.1e-56 191.3 0.0 2.9e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Shisa PF13908.1 ETS80583.1 - 0.0052 16.9 11.8 0.025 14.7 0.8 2.4 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 ETS80583.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 ETS80583.1 - 0.026 13.9 0.2 0.047 13.1 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 ETS80583.1 - 1 8.7 3.8 1.9 7.8 2.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_S7e PF01251.13 ETS80584.1 - 9.1e-82 273.1 0.1 1e-81 272.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 ETS80585.1 - 7.7e-111 371.2 0.0 1.4e-110 370.3 0.0 1.3 1 1 0 1 1 1 1 Dynactin p62 family Dynactin_p62 PF05502.8 ETS80586.1 - 1.7e-20 73.3 4.6 2.4e-20 72.7 3.2 1.2 1 0 0 1 1 1 1 Dynactin p62 family zf-B_box PF00643.19 ETS80586.1 - 0.029 14.2 3.1 0.029 14.2 2.2 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-C3HC4_3 PF13920.1 ETS80586.1 - 0.43 10.2 8.6 0.41 10.3 4.3 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mu-like_Com PF10122.4 ETS80586.1 - 1.8 7.6 9.5 3.5 6.7 4.1 2.8 2 1 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 ETS80586.1 - 2.5 7.7 6.8 5.1 6.7 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS80586.1 - 2.9 7.6 6.8 5.3 6.8 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 ETS80586.1 - 4.6 6.8 12.0 3.5 7.2 0.2 3.2 2 1 1 3 3 3 0 InsA N-terminal domain Amidase PF01425.16 ETS80588.1 - 3.7e-89 299.6 1.2 4.9e-89 299.2 0.9 1.1 1 0 0 1 1 1 1 Amidase Mito_fiss_reg PF05308.6 ETS80589.1 - 0.37 10.1 2.3 0.4 10.0 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 ETS80589.1 - 6.3 5.9 5.6 7.6 5.7 3.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EBP PF05241.7 ETS80590.1 - 1.2e-06 27.7 1.9 2.4e-06 26.7 1.3 1.5 1 1 0 1 1 1 1 Emopamil binding protein Zn_clus PF00172.13 ETS80591.1 - 0.0003 20.6 13.1 0.00055 19.7 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.1 ETS80592.1 - 4.3e-10 39.4 0.0 1.1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS80592.1 - 5.7e-09 35.5 1.1 1.1e-08 34.6 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS80592.1 - 1.2e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS80592.1 - 3.8e-06 26.0 2.8 5.6e-06 25.4 1.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS80592.1 - 6.1e-06 25.3 2.7 9.4e-06 24.7 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS80592.1 - 6.7e-06 25.3 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS80592.1 - 2e-05 24.7 0.2 4.5e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS80592.1 - 0.00012 20.6 0.8 0.00018 20.1 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETS80592.1 - 0.00017 21.8 0.2 0.00033 21.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS80592.1 - 0.0015 18.4 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS80592.1 - 0.0015 17.6 0.8 0.0028 16.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS80592.1 - 0.013 14.3 0.2 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 ETS80592.1 - 0.041 14.1 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TPR_12 PF13424.1 ETS80593.1 - 1.7e-05 24.6 1.6 1.7e-05 24.6 1.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80593.1 - 8.6e-05 22.0 2.6 0.002 17.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DOG1 PF14144.1 ETS80593.1 - 0.0073 16.3 0.0 0.09 12.8 0.0 2.8 2 0 0 2 2 2 1 Seed dormancy control TPR_2 PF07719.12 ETS80593.1 - 0.041 13.8 0.1 0.041 13.8 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80593.1 - 0.056 13.2 0.2 0.056 13.2 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS80593.1 - 0.16 11.6 5.9 0.59 9.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80593.1 - 0.17 11.5 6.6 0.29 10.8 0.1 3.6 3 2 1 4 4 4 0 TPR repeat HET PF06985.6 ETS80593.1 - 0.28 11.3 3.5 0.6 10.2 0.2 2.9 2 1 0 3 3 3 0 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.1 ETS80593.1 - 1.2 9.9 12.4 0.91 10.3 0.1 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 ETS80596.1 - 0.025 14.8 0.4 0.025 14.8 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS80596.1 - 0.041 14.2 4.8 1.2 9.5 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3671 PF12420.3 ETS80597.1 - 6.6 6.7 8.9 2 8.4 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function Ribosomal_L1 PF00687.16 ETS80598.1 - 7.3e-51 172.6 0.2 8.7e-51 172.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NUDIX PF00293.23 ETS80599.1 - 3.2e-17 62.4 0.0 6.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 ETS80599.1 - 4.9e-14 52.4 0.0 1.6e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 ETS80599.1 - 9e-08 31.5 0.4 1.8e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain RabGAP-TBC PF00566.13 ETS80600.1 - 5.9e-29 101.0 0.1 8.6e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FYVE PF01363.16 ETS80602.1 - 0.005 16.6 1.1 0.0094 15.8 0.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger Zn_Tnp_IS91 PF14319.1 ETS80602.1 - 0.038 13.5 1.4 0.077 12.5 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-B_box PF00643.19 ETS80602.1 - 0.6 10.0 3.8 1 9.3 2.6 1.3 1 0 0 1 1 1 0 B-box zinc finger MFS_1 PF07690.11 ETS80603.1 - 3.1e-41 141.2 47.2 6.9e-41 140.1 32.7 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS80603.1 - 1.4e-12 46.9 7.2 1.4e-12 46.9 5.0 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter DHFR_1 PF00186.14 ETS80604.1 - 3.8e-31 107.8 0.0 1.4e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 Dihydrofolate reductase Pkinase PF00069.20 ETS80605.1 - 4.2e-32 111.3 0.0 8.8e-32 110.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80605.1 - 2e-10 40.1 0.1 0.00051 19.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 ETS80605.1 - 0.00096 18.2 0.1 0.0019 17.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS80605.1 - 0.045 13.4 0.2 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family IBR PF01485.16 ETS80606.1 - 1.2e-10 41.0 21.7 3.6e-10 39.5 0.4 3.7 3 1 0 3 3 3 2 IBR domain RNHCP PF12647.2 ETS80606.1 - 0.26 11.1 6.9 0.42 10.4 1.6 2.8 2 0 0 2 2 2 0 RNHCP domain C1_4 PF07975.7 ETS80606.1 - 8.1 6.5 11.5 3.2 7.8 1.1 3.4 3 0 0 3 3 3 0 TFIIH C1-like domain MliC PF09864.4 ETS80607.1 - 0.031 14.0 0.4 0.051 13.3 0.2 1.3 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Ank_2 PF12796.2 ETS80608.1 - 5.8e-70 231.6 1.2 1.5e-24 86.1 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80608.1 - 1.8e-63 207.3 6.3 2.6e-12 45.8 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETS80608.1 - 4e-49 163.5 5.7 4.1e-13 49.1 0.0 6.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80608.1 - 4.1e-49 159.6 0.1 1.8e-08 33.7 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 ETS80608.1 - 5.8e-46 154.0 1.8 1.7e-12 47.4 0.0 4.9 4 1 1 5 5 4 4 Ankyrin repeats (many copies) TPR_12 PF13424.1 ETS80608.1 - 1.6e-08 34.3 13.1 0.002 17.9 0.1 5.7 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80608.1 - 8.2e-08 31.7 13.3 0.0042 16.7 0.5 5.1 1 1 5 6 6 6 3 TPR repeat TPR_7 PF13176.1 ETS80608.1 - 4.7e-06 25.9 6.6 0.24 11.2 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80608.1 - 0.00023 20.8 17.2 0.6 10.1 0.5 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80608.1 - 0.00056 19.5 7.9 7.2 6.6 0.2 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TOM20_plant PF06552.7 ETS80608.1 - 0.0016 18.0 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_1 PF00515.23 ETS80608.1 - 0.0019 17.6 17.6 0.2 11.2 0.4 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80608.1 - 0.004 17.6 7.1 1.7 9.5 0.2 5.6 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS80608.1 - 0.11 12.8 8.9 7.7 6.9 0.5 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 ETS80608.1 - 0.21 11.4 5.9 37 4.2 0.1 5.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 ETS80608.1 - 0.24 12.0 4.1 5.9 7.6 0.5 3.9 3 0 0 3 3 2 0 Sel1 repeat TPR_16 PF13432.1 ETS80608.1 - 1.3 9.7 10.9 5 7.9 1.9 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat HET PF06985.6 ETS80609.1 - 4.1e-18 65.8 2.0 7.2e-18 65.0 1.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.8 ETS80610.1 - 0.014 15.4 0.2 0.1 12.6 0.1 2.1 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3425 PF11905.3 ETS80610.1 - 0.035 14.0 0.3 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) NAGLU PF05089.7 ETS80610.1 - 0.05 12.3 0.1 0.074 11.7 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Prim_Zn_Ribbon PF08273.7 ETS80610.1 - 0.16 12.0 0.6 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Hydrolase_6 PF13344.1 ETS80611.1 - 4.2e-28 97.1 0.0 7e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS80611.1 - 1.3e-13 50.4 0.0 4.8e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS80611.1 - 3.4e-11 43.9 0.0 1.3e-10 42.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS80611.1 - 2.9e-07 30.8 0.0 0.00023 21.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS80611.1 - 0.11 12.6 0.0 0.81 9.8 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glucosamine_iso PF01182.15 ETS80612.1 - 4.8e-59 199.4 0.0 6.1e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ubiq_cyt_C_chap PF03981.7 ETS80613.1 - 5.9e-39 133.1 0.1 9.1e-39 132.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ketoacyl-synt PF00109.21 ETS80614.1 - 1.1e-57 195.3 6.1 3.5e-57 193.7 1.1 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS80614.1 - 4.3e-29 100.7 1.1 8.1e-27 93.4 0.4 2.2 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 ETS80614.1 - 0.00021 20.3 0.2 0.0019 17.2 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS80614.1 - 0.11 11.9 4.9 2.3 7.6 0.2 3.6 2 2 0 2 2 2 0 Thiolase, C-terminal domain OPT PF03169.10 ETS80615.1 - 1.4e-188 628.2 56.5 1.6e-188 628.0 39.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 ETS80615.1 - 0.038 13.7 0.3 0.14 11.9 0.2 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FAD_binding_3 PF01494.14 ETS80616.1 - 9.3e-15 54.5 0.9 2.7e-13 49.7 0.3 2.8 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS80616.1 - 2.8e-06 26.4 3.7 0.0057 15.6 1.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS80616.1 - 3.1e-06 27.1 0.3 8.8e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS80616.1 - 4.3e-06 26.7 3.6 8.6e-05 22.4 2.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS80616.1 - 0.0031 17.6 0.2 0.0084 16.1 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS80616.1 - 0.0047 15.8 0.6 0.0047 15.8 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ETS80616.1 - 0.0048 15.7 4.4 0.0083 15.0 1.9 2.0 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 ETS80616.1 - 0.012 15.2 0.2 0.012 15.2 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 ETS80616.1 - 0.026 13.6 1.3 0.044 12.8 0.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS80616.1 - 0.044 14.1 1.1 0.044 14.1 0.8 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS80616.1 - 0.049 12.0 1.7 0.065 11.6 0.7 1.5 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 ETS80616.1 - 0.096 11.7 0.3 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 ETS80616.1 - 0.1 12.2 0.4 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 ETS80616.1 - 0.11 11.0 3.2 9.6 4.6 0.5 3.0 3 0 0 3 3 3 0 Tryptophan halogenase WD40 PF00400.27 ETS80617.1 - 1.2e-45 151.8 13.4 7.1e-09 35.2 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 ETS80617.1 - 9.9e-10 38.0 0.1 1.9e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS80617.1 - 1.6e-07 30.7 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 ETS80617.1 - 1.7e-06 26.4 0.7 0.076 11.1 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS80617.1 - 0.0098 14.2 0.1 0.018 13.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain FlaG PF03646.10 ETS80617.1 - 0.01 15.9 0.0 1.1 9.4 0.0 3.3 3 0 0 3 3 3 0 FlaG protein SRI PF08236.6 ETS80619.1 - 2e-22 78.9 10.4 4.8e-22 77.7 7.2 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 ETS80619.1 - 2e-21 76.9 0.4 2e-21 76.9 0.3 3.2 2 2 0 2 2 2 1 SET domain WW PF00397.21 ETS80619.1 - 0.0014 18.4 1.5 0.003 17.3 1.1 1.6 1 0 0 1 1 1 1 WW domain CENP-O PF09496.5 ETS80619.1 - 0.071 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Pkinase PF00069.20 ETS80620.1 - 4.8e-58 196.3 0.0 6.7e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80620.1 - 1.5e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80620.1 - 7.4e-07 28.4 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS80620.1 - 0.00026 20.1 0.1 0.00051 19.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS80620.1 - 0.00056 19.7 0.4 0.0021 17.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 ETS80620.1 - 0.0011 18.3 0.1 0.0023 17.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Shisa PF13908.1 ETS80621.1 - 0.0017 18.5 7.4 0.045 13.9 5.1 2.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 ETS80621.1 - 0.0018 17.9 0.0 0.0053 16.4 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 ETS80621.1 - 0.0035 17.7 0.0 0.0035 17.7 0.0 2.4 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 ETS80621.1 - 0.014 15.1 1.9 0.036 13.7 0.0 2.5 2 1 0 3 3 3 0 FAM176 family Tweety PF04906.8 ETS80621.1 - 0.024 13.0 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Tweety Macoilin PF09726.4 ETS80621.1 - 0.033 12.4 11.0 0.034 12.4 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein P12 PF12669.2 ETS80621.1 - 0.038 14.1 0.1 0.096 12.8 0.1 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family Adeno_E3_CR2 PF02439.10 ETS80621.1 - 0.042 13.4 1.7 0.085 12.4 1.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ctr PF04145.10 ETS80621.1 - 0.064 13.3 7.1 0.12 12.3 0.0 2.5 1 1 1 2 2 2 0 Ctr copper transporter family Syndecan PF01034.15 ETS80621.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.1 ETS80621.1 - 0.14 12.3 0.3 0.93 9.6 0.0 2.4 1 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT AJAP1_PANP_C PF15298.1 ETS80621.1 - 0.15 11.9 2.9 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus FAM163 PF15069.1 ETS80621.1 - 0.62 10.6 3.6 2.9 8.4 2.5 2.2 1 1 0 1 1 1 0 FAM163 family DUF1183 PF06682.7 ETS80621.1 - 3.6 7.1 11.9 44 3.5 5.6 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1183) His_Phos_1 PF00300.17 ETS80622.1 - 6.3e-22 78.3 0.0 8.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1762 PF08574.5 ETS80624.1 - 5.2e-07 29.9 13.1 5.2e-07 29.9 9.1 3.0 4 1 1 5 5 5 1 Protein of unknown function (DUF1762) Pyridoxal_deC PF00282.14 ETS80627.1 - 9.9e-20 70.2 0.0 3.7e-11 42.0 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 ETS80627.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans_2 PF11951.3 ETS80629.1 - 0.00014 20.5 1.3 0.00014 20.5 0.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ank_2 PF12796.2 ETS80630.1 - 2.8e-44 149.3 1.6 3.3e-15 56.1 0.0 5.5 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80630.1 - 1e-32 110.2 12.0 6.8e-06 25.6 0.0 10.3 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 ETS80630.1 - 4.2e-29 100.3 4.3 2.6e-08 34.1 0.0 7.1 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS80630.1 - 4.2e-25 87.1 6.9 5.8e-11 42.2 0.1 6.3 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80630.1 - 2.1e-21 73.8 10.5 0.00038 20.4 0.1 10.0 10 0 0 10 10 9 4 Ankyrin repeat NACHT PF05729.7 ETS80630.1 - 9.5e-06 25.3 0.2 6.7e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS80630.1 - 1.5e-05 25.1 0.0 4.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS80630.1 - 3e-05 24.0 0.1 9.6e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 ETS80630.1 - 0.0034 17.5 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 ETS80630.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 ETS80630.1 - 0.024 14.5 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 ETS80630.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS80630.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.8 ETS80630.1 - 0.097 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_10 PF12846.2 ETS80630.1 - 0.26 10.6 0.0 0.78 9.1 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain DUF1682 PF07946.9 ETS80630.1 - 0.33 9.7 0.0 1.9 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) PIF1 PF05970.9 ETS80630.1 - 0.35 9.7 0.0 0.61 8.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase LRR19-TM PF15176.1 ETS80633.1 - 0.34 10.6 1.5 7.7 6.2 0.4 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3433 PF11915.3 ETS80635.1 - 2.4e-20 72.4 17.0 5.3e-12 45.7 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) AAA PF00004.24 ETS80636.1 - 9.3e-22 77.6 0.0 3e-10 40.4 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS80636.1 - 5.1e-10 40.2 0.0 0.0017 19.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS80636.1 - 5.1e-08 32.5 0.6 0.0082 15.8 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 ETS80636.1 - 1e-07 31.7 0.1 0.001 18.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS80636.1 - 1.6e-07 31.5 2.8 0.063 13.4 0.0 5.1 3 3 0 4 4 4 2 AAA domain AAA_18 PF13238.1 ETS80636.1 - 3.5e-06 27.3 0.6 0.1 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 ETS80636.1 - 4.2e-06 26.6 0.1 0.08 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 ETS80636.1 - 2.6e-05 23.4 0.4 0.076 12.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 ETS80636.1 - 4.1e-05 23.6 0.5 0.42 10.5 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 ETS80636.1 - 4.7e-05 23.2 0.0 0.26 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 ETS80636.1 - 4.9e-05 22.4 0.1 0.12 11.4 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 ETS80636.1 - 9.6e-05 22.0 0.0 0.051 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 ETS80636.1 - 0.00013 22.0 0.0 1.3 9.1 0.0 4.1 3 2 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETS80636.1 - 0.00075 18.6 0.4 0.025 13.6 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 ETS80636.1 - 0.0012 18.9 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 ETS80636.1 - 0.0013 18.3 1.3 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ETS80636.1 - 0.0021 17.5 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 ETS80636.1 - 0.0046 16.9 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 ETS80636.1 - 0.0082 15.6 0.0 0.083 12.3 0.0 2.5 3 0 0 3 3 3 1 Virulence-associated protein E AAA_11 PF13086.1 ETS80636.1 - 0.01 15.4 0.0 3.1 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 ETS80636.1 - 0.011 15.2 0.1 1.5 8.2 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 ETS80636.1 - 0.011 15.4 0.8 0.21 11.2 0.0 2.9 2 1 0 2 2 2 0 NACHT domain KTI12 PF08433.5 ETS80636.1 - 0.038 13.1 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 ETS80636.1 - 0.073 12.0 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain Torsin PF06309.6 ETS80636.1 - 0.076 12.8 0.1 2.1 8.2 0.0 2.8 3 0 0 3 3 2 0 Torsin PhoH PF02562.11 ETS80636.1 - 0.084 12.0 0.2 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 ETS80636.1 - 0.091 13.0 0.0 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 ETS80636.1 - 0.1 11.9 5.8 6.9 6.0 0.6 4.1 4 1 0 4 4 4 0 AAA-like domain NTPase_1 PF03266.10 ETS80636.1 - 0.11 12.2 0.1 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 ETS80636.1 - 0.2 11.0 0.6 10 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETS80636.1 - 0.35 10.2 1.4 16 4.8 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain HET PF06985.6 ETS80637.1 - 3.9e-27 95.1 0.4 1.2e-26 93.5 0.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S66 PF02016.10 ETS80638.1 - 6.3e-61 205.8 0.0 7.3e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 LD-carboxypeptidase GMC_oxred_C PF05199.8 ETS80639.1 - 6.9e-17 62.0 0.2 3.2e-16 59.9 0.1 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS80639.1 - 7.2e-07 28.6 0.0 2.6e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.14 ETS80639.1 - 3.9e-06 26.1 0.1 6.1e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS80639.1 - 0.0059 16.5 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS80639.1 - 0.0096 14.8 0.3 0.98 8.2 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS80639.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 ETS80639.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 ETS80639.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 ETS80639.1 - 0.13 11.1 0.1 4.9 5.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 ETS80639.1 - 0.18 11.8 0.2 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DEAD PF00270.24 ETS80641.1 - 2.8e-29 101.7 0.0 6.9e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS80641.1 - 4.8e-17 61.5 0.1 1e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS80641.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TIP41 PF04176.8 ETS80643.1 - 2.9e-72 241.7 0.1 3.7e-72 241.3 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family zf-C2H2 PF00096.21 ETS80644.1 - 3.8e-07 30.0 17.0 1.4e-05 25.0 2.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS80644.1 - 2.6e-05 24.3 3.8 2.6e-05 24.3 2.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS80644.1 - 0.0003 20.8 1.0 0.00085 19.3 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 ETS80644.1 - 0.00051 20.1 0.9 0.00051 20.1 0.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-TRAF PF02176.13 ETS80644.1 - 0.062 13.6 3.0 0.13 12.6 2.1 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.2 ETS80644.1 - 0.095 12.9 0.8 0.3 11.3 0.5 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 ETS80644.1 - 0.13 12.1 0.6 0.56 10.1 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETS80644.1 - 1.7 8.7 6.2 0.97 9.5 2.2 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.8 ETS80644.1 - 3.4 7.7 6.8 0.36 10.9 1.0 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 SET PF00856.23 ETS80645.1 - 6.2e-09 36.3 0.1 0.0011 19.2 0.1 3.0 3 1 0 3 3 3 2 SET domain TPR_11 PF13414.1 ETS80645.1 - 0.016 14.7 1.0 2.3 7.9 0.1 2.8 3 0 0 3 3 3 0 TPR repeat RPAP2_Rtr1 PF04181.8 ETS80645.1 - 0.58 10.2 5.6 1.6 8.8 1.2 2.4 2 0 0 2 2 2 0 Rtr1/RPAP2 family TPR_16 PF13432.1 ETS80645.1 - 0.71 10.6 4.9 0.32 11.7 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.13 ETS80645.1 - 2.1 8.2 12.7 0.25 11.2 4.6 2.5 2 0 0 2 2 2 0 MYND finger PTS_2-RNA PF01885.11 ETS80647.1 - 3e-65 219.0 0.0 3.8e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CDT1 PF08839.6 ETS80647.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor CDT1 like Sugar_tr PF00083.19 ETS80649.1 - 1.4e-99 333.7 22.7 1.7e-99 333.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80649.1 - 5.3e-23 81.3 32.0 1.4e-20 73.3 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS80649.1 - 0.00014 20.2 0.5 0.00014 20.2 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PsaM PF07465.8 ETS80649.1 - 0.015 14.8 0.4 0.015 14.8 0.3 2.2 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Med21 PF11221.3 ETS80651.1 - 0.03 14.2 1.3 0.52 10.2 0.1 2.4 3 0 0 3 3 3 0 Subunit 21 of Mediator complex PH PF00169.24 ETS80653.1 - 0.035 14.2 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 PH domain RmlD_sub_bind PF04321.12 ETS80654.1 - 2.3e-55 187.5 0.0 2.8e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 ETS80654.1 - 2.8e-22 79.3 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS80654.1 - 5.1e-12 45.2 0.0 5e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 ETS80654.1 - 4.5e-07 29.0 0.1 0.00081 18.3 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 ETS80654.1 - 1.1e-06 27.5 0.0 4.2e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS80654.1 - 7.8e-06 26.0 0.1 1e-05 25.6 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS80654.1 - 0.00096 19.1 1.9 0.0095 15.8 1.3 2.4 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETS80654.1 - 0.0017 17.6 0.2 0.039 13.1 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 ETS80654.1 - 0.052 13.2 0.1 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 KR domain DapB_N PF01113.15 ETS80654.1 - 0.068 13.0 0.1 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_4 PF01565.18 ETS80656.1 - 4.3e-20 71.5 2.7 4.3e-20 71.5 1.9 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS80656.1 - 1.1e-07 31.6 0.4 1.1e-07 31.6 0.3 2.5 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS80656.1 - 0.12 11.5 0.2 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding AA_permease_2 PF13520.1 ETS80657.1 - 3.6e-36 124.6 44.5 4.5e-36 124.2 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease ILVD_EDD PF00920.16 ETS80658.1 - 5.9e-76 255.9 0.1 6.9e-76 255.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family ApbA PF02558.11 ETS80658.1 - 0.018 14.4 0.8 0.031 13.7 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glycos_transf_3 PF00591.16 ETS80658.1 - 0.08 12.3 0.1 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain Aminotran_4 PF01063.14 ETS80659.1 - 2.9e-16 59.6 0.0 3.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV RTA1 PF04479.8 ETS80660.1 - 1.4e-39 135.9 3.6 1.8e-39 135.5 2.5 1.1 1 0 0 1 1 1 1 RTA1 like protein MARVEL PF01284.18 ETS80660.1 - 0.078 12.8 16.7 0.84 9.4 1.0 2.9 2 1 0 2 2 2 0 Membrane-associating domain zf-DHHC PF01529.15 ETS80660.1 - 1.2 8.5 4.1 2.7 7.3 0.0 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase ATG16 PF08614.6 ETS80661.1 - 0.06 13.1 7.3 0.15 11.9 0.9 2.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF455 PF04305.9 ETS80661.1 - 1.9 7.6 8.4 0.14 11.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Peptidase_C37 PF05416.7 ETS80661.1 - 2.4 6.3 8.3 4.7 5.3 5.7 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase B-block_TFIIIC PF04182.7 ETS80662.1 - 1e-12 47.7 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HrcA PF01628.16 ETS80662.1 - 0.1 12.1 0.2 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 HrcA protein C terminal domain UQ_con PF00179.21 ETS80663.1 - 8.4e-21 73.8 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS80663.1 - 0.041 13.7 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 ETS80663.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B PAT1 PF09770.4 ETS80663.1 - 0.51 8.5 9.5 0.63 8.2 6.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UvsY PF11056.3 ETS80664.1 - 0.0085 16.2 0.3 0.096 12.8 0.1 2.2 2 0 0 2 2 2 1 Recombination, repair and ssDNA binding protein UvsY UBA_4 PF14555.1 ETS80664.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain UIM PF02809.15 ETS80664.1 - 2.7 7.7 8.1 2.2 8.0 2.5 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Init_tRNA_PT PF04179.7 ETS80665.1 - 1.7e-162 541.3 0.0 2.7e-162 540.7 0.0 1.3 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DnaJ PF00226.26 ETS80666.1 - 2.9e-27 94.1 3.5 4.4e-27 93.5 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 ETS80666.1 - 3.6e-22 78.0 2.6 1.2e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain UQ_con PF00179.21 ETS80667.1 - 1.5e-36 124.8 0.0 1.9e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS80667.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 ETS80667.1 - 0.096 12.5 0.2 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 RWD domain Nop14 PF04147.7 ETS80667.1 - 6.3 4.5 9.6 7.9 4.2 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Rox3 PF08633.5 ETS80668.1 - 1.1e-44 153.0 0.3 1.1e-44 153.0 0.2 2.1 2 0 0 2 2 2 1 Rox3 mediator complex subunit DUF1076 PF06416.7 ETS80668.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Cut8_N PF14482.1 ETS80668.1 - 3.7 7.6 12.9 2.6 8.0 0.2 4.0 3 2 0 3 3 3 0 Cut8 proteasome-binding domain PGAP1 PF07819.8 ETS80669.1 - 3.2e-06 26.8 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 ETS80669.1 - 1.6e-05 24.8 0.1 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80669.1 - 4.9e-05 23.1 0.0 9.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS80669.1 - 0.0024 17.5 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 ETS80669.1 - 0.0039 17.4 2.1 0.0065 16.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 ETS80669.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 ETS80669.1 - 0.0066 15.7 0.8 0.016 14.5 0.0 1.9 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 ETS80669.1 - 0.0081 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 ETS80669.1 - 0.014 14.4 0.1 0.054 12.4 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase ING PF12998.2 ETS80669.1 - 0.026 14.8 0.4 0.054 13.7 0.3 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding UPF0227 PF05728.7 ETS80669.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2305 PF10230.4 ETS80669.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 ETS80669.1 - 0.067 12.5 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4407 PF14362.1 ETS80669.1 - 1 8.2 5.9 1.4 7.7 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hep_59 PF07052.6 ETS80669.1 - 3.9 7.8 11.0 13 6.1 7.6 2.0 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Atg14 PF10186.4 ETS80669.1 - 4.4 6.1 6.8 6.6 5.5 4.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Glyco_hydro_3 PF00933.16 ETS80670.1 - 1.6e-88 296.6 0.0 2.1e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS80670.1 - 1.6e-52 178.2 0.1 4.1e-51 173.7 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS80670.1 - 4.5e-22 77.7 0.2 8.2e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_A2B PF12384.3 ETS80670.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase CARDB PF07705.6 ETS80670.1 - 0.025 14.5 0.1 0.076 13.0 0.1 1.7 1 0 0 1 1 1 0 CARDB Lipase_3 PF01764.20 ETS80671.1 - 1.1e-35 122.3 0.1 3e-35 120.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.11 ETS80671.1 - 0.0037 17.0 0.2 0.0091 15.7 0.1 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 ETS80671.1 - 0.031 14.0 0.5 0.077 12.7 0.2 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 ETS80671.1 - 0.051 13.3 5.4 0.028 14.1 1.2 2.4 2 1 0 2 2 2 0 Cutinase PGAP1 PF07819.8 ETS80671.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein FMO-like PF00743.14 ETS80672.1 - 2.5e-23 82.0 0.1 1.6e-15 56.3 0.0 3.7 4 1 0 4 4 4 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS80672.1 - 1.1e-13 51.6 0.0 7.1e-13 49.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS80672.1 - 3.4e-09 36.8 0.0 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS80672.1 - 5.3e-07 29.5 7.0 7.5e-06 25.7 1.7 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS80672.1 - 8.6e-06 25.6 0.0 6.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DJ-1_PfpI PF01965.19 ETS80672.1 - 0.00084 18.8 0.1 0.52 9.7 0.1 2.5 2 1 0 2 2 2 2 DJ-1/PfpI family K_oxygenase PF13434.1 ETS80672.1 - 0.00088 18.2 1.0 0.017 14.0 0.4 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 ETS80672.1 - 0.024 13.7 0.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AA_permease_2 PF13520.1 ETS80673.1 - 5.7e-60 203.0 44.4 7.5e-60 202.6 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS80673.1 - 1.2e-28 99.7 31.4 1.2e-28 99.7 21.7 2.3 2 1 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 ETS80674.1 - 4.1e-52 177.0 0.0 4.2e-29 101.0 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 ETS80674.1 - 3.6e-33 114.4 0.0 6.6e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 ETS80674.1 - 1.1e-30 106.6 0.2 5.2e-22 78.0 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 ETS80674.1 - 2.4e-13 50.0 0.0 5.2e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 ETS80674.1 - 0.0015 17.4 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) PSRT PF07636.6 ETS80674.1 - 0.032 13.7 1.6 0.08 12.4 1.1 1.6 1 0 0 1 1 1 0 PSRT tRNA-synt_1e PF01406.14 ETS80674.1 - 0.05 12.7 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Methyltransf_26 PF13659.1 ETS80675.1 - 1.1e-14 54.4 0.4 4.1e-14 52.6 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80675.1 - 3.9e-08 33.0 0.0 1.6e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80675.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS80675.1 - 3.4e-05 24.1 0.0 9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS80675.1 - 0.0002 20.7 0.0 0.013 14.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 ETS80675.1 - 0.012 15.2 0.0 0.16 11.7 0.0 2.4 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80675.1 - 0.015 15.7 0.0 0.051 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 ETS80675.1 - 0.031 13.8 0.0 0.61 9.6 0.0 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 ETS80675.1 - 0.046 12.8 0.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 ETS80675.1 - 0.049 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.11 ETS80675.1 - 0.098 11.7 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase Suc_Fer-like PF06999.7 ETS80676.1 - 7.5e-53 179.9 0.0 8.9e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.19 ETS80677.1 - 3.7e-10 39.8 0.0 8.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 ETS80677.1 - 0.00034 21.1 0.0 0.00068 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETS80677.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Epimerase PF01370.16 ETS80678.1 - 6.8e-10 38.7 0.1 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS80678.1 - 2.8e-08 33.9 0.0 4.8e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS80678.1 - 3.3e-06 26.0 0.1 3.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETS80678.1 - 0.00029 20.1 0.1 0.00071 18.8 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 ETS80678.1 - 0.0015 17.5 0.1 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 ETS80678.1 - 0.0083 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 ETS80678.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETS80678.1 - 0.053 12.9 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Na_H_Exchanger PF00999.16 ETS80679.1 - 1e-55 188.8 21.0 1.4e-55 188.4 14.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.22 ETS80680.1 - 1.4e-59 197.8 1.8 6.6e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 ETS80681.1 - 2.3e-32 110.4 0.0 8.1e-16 57.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS80681.1 - 2.7e-16 59.3 0.0 2.8e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS80681.1 - 6.4e-13 48.3 0.0 6.2e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 ETS80681.1 - 0.00075 18.9 1.7 0.077 12.5 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain CMV_1a_C PF12503.3 ETS80681.1 - 0.0091 15.7 0.2 2 8.1 0.1 2.3 2 0 0 2 2 2 2 Cucumber mosaic virus 1a protein C terminal zf-H2C2_2 PF13465.1 ETS80682.1 - 9.4e-10 38.3 8.1 1e-06 28.7 1.1 5.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETS80682.1 - 4.3e-09 36.1 46.3 0.00055 20.1 1.3 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS80682.1 - 7e-05 22.8 48.5 0.0051 17.0 0.1 5.9 5 1 0 5 5 5 4 C2H2-type zinc finger Nop53 PF07767.6 ETS80682.1 - 0.76 8.7 12.3 1.6 7.6 8.5 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 ETS80682.1 - 1.7 6.6 9.9 2.6 5.9 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 ETS80682.1 - 2.3 7.7 12.2 4 6.9 8.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 ETS80682.1 - 5.1 7.3 11.7 13 6.0 8.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Urm1 PF09138.6 ETS80683.1 - 7.8e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DUF2823 PF11034.3 ETS80686.1 - 1.1e-30 105.5 11.0 1.2e-30 105.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF3570 PF12094.3 ETS80686.1 - 0.025 13.3 1.2 0.027 13.2 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) Ribosomal_L38e PF01781.13 ETS80687.1 - 3.4e-33 113.2 1.8 4.1e-33 112.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.6 ETS80687.1 - 0.064 12.9 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein DNA_pol_B PF00136.16 ETS80688.1 - 7e-144 480.0 3.5 1e-143 479.5 2.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETS80688.1 - 8.2e-80 268.0 0.3 1.7e-79 267.0 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 ETS80688.1 - 5.9e-23 80.6 4.9 1.4e-22 79.4 3.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 ETS80688.1 - 0.00011 22.0 0.4 0.00056 19.7 0.3 2.3 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 ETS80688.1 - 0.024 14.3 0.8 0.024 14.3 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELFV_dehydrog PF00208.16 ETS80689.1 - 1e-84 283.9 2.3 1.3e-84 283.6 1.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 ETS80689.1 - 2.1e-48 163.2 0.0 4.1e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 ETS80689.1 - 0.0091 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding GMC_oxred_C PF05199.8 ETS80690.1 - 1.9e-08 34.6 0.6 5.4e-07 29.9 0.0 3.3 4 0 0 4 4 4 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS80690.1 - 1.5e-07 30.8 0.1 1.2e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS80690.1 - 0.00025 20.0 0.3 0.0005 19.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS80690.1 - 0.0021 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS80690.1 - 0.0075 16.2 0.7 0.027 14.4 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS80690.1 - 0.02 13.7 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 ETS80690.1 - 0.021 13.7 0.0 0.052 12.4 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS80690.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS80690.1 - 0.09 13.1 0.5 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS80690.1 - 0.19 10.1 0.1 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF900 PF05990.7 ETS80690.1 - 0.21 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) p450 PF00067.17 ETS80694.1 - 1.5e-30 106.1 0.0 2.4e-14 52.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 ETS80696.1 - 6.8e-26 90.8 25.4 6.8e-26 90.8 17.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 ETS80697.1 - 4.4e-12 46.2 0.1 1.5e-11 44.5 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS80697.1 - 1.3e-05 24.9 0.0 3.7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS80697.1 - 0.00061 19.6 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 ETS80697.1 - 0.0024 17.1 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS80697.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 ETS80697.1 - 0.047 13.6 0.0 0.24 11.3 0.0 2.1 2 1 0 2 2 2 0 TrkA-N domain DUF3328 PF11807.3 ETS80698.1 - 3.1e-42 144.7 0.3 4e-42 144.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LRR19-TM PF15176.1 ETS80698.1 - 0.033 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HET PF06985.6 ETS80699.1 - 2.9e-20 72.8 5.8 4.3e-18 65.8 4.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.1 ETS80701.1 - 5e-25 88.8 0.0 8.4e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS80701.1 - 1.9e-13 50.0 0.1 3.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS80701.1 - 1e-05 25.2 0.0 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain Prenyltrans_2 PF13249.1 ETS80703.1 - 5.9e-21 74.9 2.2 1.1e-09 38.7 0.0 4.7 1 1 4 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS80703.1 - 2.1e-14 53.4 0.4 2.2e-09 37.3 0.0 3.3 3 1 0 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 ETS80703.1 - 5.8e-08 32.1 14.4 5.8e-05 22.5 0.4 4.1 4 1 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 ETS80703.1 - 0.00029 20.1 0.0 0.0037 16.4 0.0 2.7 2 1 0 2 2 2 1 Pectic acid lyase A2M_comp PF07678.9 ETS80703.1 - 0.0024 17.1 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 A-macroglobulin complement component Prenyltrans_2 PF13249.1 ETS80704.1 - 6.7e-08 32.9 0.1 9.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans PF00432.16 ETS80704.1 - 3.3e-06 26.5 0.1 1.9e-05 24.1 0.0 2.2 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 ETS80704.1 - 9.8e-06 25.5 0.0 0.026 14.5 0.0 2.0 1 1 1 2 2 2 2 Prenyltransferase-like p450 PF00067.17 ETS80705.1 - 1.1e-70 238.4 0.0 1.4e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.28 ETS80707.1 - 2.9e-06 26.7 0.1 7.4e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS80707.1 - 0.0064 16.2 0.3 0.019 14.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like PAN_4 PF14295.1 ETS80708.1 - 5.4e-07 29.2 1.8 0.2 11.4 0.0 3.6 3 0 0 3 3 3 2 PAN domain MANEC PF07502.9 ETS80708.1 - 3.7e-05 23.6 2.9 0.58 10.1 0.0 3.3 3 0 0 3 3 3 2 MANEC domain SANTA PF09133.5 ETS80708.1 - 0.17 11.8 0.0 23 5.0 0.0 2.3 2 0 0 2 2 2 0 SANTA (SANT Associated) PAN_2 PF08276.6 ETS80708.1 - 0.39 10.6 4.7 9.3 6.1 0.1 3.1 3 0 0 3 3 3 0 PAN-like domain Pex14_N PF04695.8 ETS80708.1 - 1.1 9.2 7.2 3.1 7.8 5.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 ETS80708.1 - 4.2 5.5 6.4 4.5 5.4 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein MUG113 PF13455.1 ETS80709.1 - 4.7e-13 49.4 0.6 1.4e-12 47.9 0.4 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 ETS80709.1 - 2.3e-11 43.9 3.5 5.9e-10 39.4 2.4 2.7 1 1 0 1 1 1 1 T5orf172 domain HET PF06985.6 ETS80710.1 - 0.0001 22.5 2.1 0.00033 20.8 0.0 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1764 PF08576.5 ETS80710.1 - 1.3 9.8 4.6 3.1 8.6 3.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Rhodanese PF00581.15 ETS80711.1 - 2.1e-08 34.4 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF669 PF05037.8 ETS80711.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) FMN_red PF03358.10 ETS80712.1 - 1.2e-25 89.7 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETS80712.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Abhydrolase_6 PF12697.2 ETS80713.1 - 2.9e-21 76.4 0.0 3.3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS80713.1 - 3.1e-10 39.9 0.0 5.6e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CN_hydrolase PF00795.17 ETS80714.1 - 2e-22 79.4 0.0 3.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidase PF01425.16 ETS80715.1 - 9.3e-29 100.5 1.2 5.1e-28 98.1 0.1 2.1 2 0 0 2 2 2 1 Amidase Fungal_trans PF04082.13 ETS80716.1 - 2.8e-26 91.9 0.0 5.1e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80716.1 - 9.4e-08 31.8 6.2 2e-07 30.7 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 ETS80717.1 - 1.7e-28 99.7 0.0 2.8e-27 95.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS80717.1 - 7.4e-06 25.1 0.2 0.054 12.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS80717.1 - 0.0001 22.2 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS80717.1 - 0.00016 20.6 0.0 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.19 ETS80717.1 - 0.00019 20.6 0.0 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 ETS80717.1 - 0.0011 17.7 1.0 0.4 9.2 0.1 3.1 3 1 1 4 4 4 2 Tryptophan halogenase HI0933_like PF03486.9 ETS80717.1 - 0.0012 17.3 0.0 0.0069 14.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS80717.1 - 0.0035 17.2 0.2 0.0058 16.5 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS80717.1 - 0.0055 15.5 0.5 0.019 13.8 0.3 1.9 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 ETS80717.1 - 0.013 14.4 0.5 0.24 10.2 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS80717.1 - 0.022 13.8 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS80717.1 - 0.11 12.2 0.3 0.41 10.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 ETS80717.1 - 0.22 10.3 0.3 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MACPF PF01823.14 ETS80719.1 - 8.4e-05 22.3 0.2 8.4e-05 22.3 0.1 3.7 5 0 0 5 5 5 1 MAC/Perforin domain Pyr_redox_3 PF13738.1 ETS80720.1 - 1.1e-24 87.6 0.0 4.3e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS80720.1 - 4.8e-14 51.4 0.6 2.2e-13 49.2 0.2 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS80720.1 - 3e-09 36.2 0.0 3.5e-07 29.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS80720.1 - 8.6e-07 28.9 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS80720.1 - 0.0015 18.3 0.3 0.03 14.0 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Ank_2 PF12796.2 ETS80721.1 - 1.7e-21 76.3 0.0 1.8e-13 50.6 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80721.1 - 1.9e-15 55.7 4.3 0.048 13.4 0.0 6.1 5 2 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 ETS80721.1 - 1.5e-12 47.6 1.6 0.048 14.1 0.1 6.5 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80721.1 - 1.3e-10 40.4 2.5 1.9 8.9 0.0 7.1 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 ETS80721.1 - 1.5e-08 34.5 4.0 0.015 15.5 0.0 5.2 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Pribosyltran PF00156.22 ETS80722.1 - 3.1e-16 59.2 0.0 6.5e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 ETS80722.1 - 3.4e-14 52.4 1.4 8e-14 51.2 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.9 ETS80722.1 - 1.9e-09 37.2 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase Methyltransf_23 PF13489.1 ETS80722.1 - 3e-05 23.7 0.0 9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPRTase PF14681.1 ETS80722.1 - 0.0029 16.8 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.7 ETS80722.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PRTase_2 PF15609.1 ETS80722.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase RrnaAD PF00398.15 ETS80722.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GTP_cyclohydroI PF01227.17 ETS80723.1 - 2.3e-14 53.0 0.0 3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I PA14_2 PF10528.4 ETS80724.1 - 2.2e-23 82.3 0.3 2.2e-23 82.3 0.2 2.3 2 1 0 2 2 2 1 GLEYA domain PA14 PF07691.7 ETS80724.1 - 8.6e-08 31.9 0.3 2.8e-07 30.2 0.2 1.9 1 1 0 1 1 1 1 PA14 domain DUF1897 PF09005.5 ETS80724.1 - 0.0029 17.0 0.2 0.0058 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) adh_short_C2 PF13561.1 ETS80725.1 - 4.3e-27 95.4 3.4 5.2e-27 95.1 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS80725.1 - 2.2e-24 86.2 7.3 3.1e-24 85.7 3.5 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS80725.1 - 2.9e-11 43.3 4.4 2.8e-10 40.1 2.2 2.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS80725.1 - 0.0028 17.1 1.6 0.005 16.2 1.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS80725.1 - 0.0079 15.1 0.2 0.013 14.4 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETS80725.1 - 0.015 15.0 2.8 0.08 12.7 1.3 2.4 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HHH_5 PF14520.1 ETS80725.1 - 0.077 13.1 0.4 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain PA PF02225.17 ETS80725.1 - 0.085 12.5 0.7 0.25 11.0 0.4 1.9 2 0 0 2 2 2 0 PA domain Ldh_1_N PF00056.18 ETS80725.1 - 0.26 11.0 3.3 0.88 9.3 0.3 2.4 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Fig1 PF12351.3 ETS80726.1 - 5.1 6.9 7.1 2.8 7.7 1.6 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 AA_permease_2 PF13520.1 ETS80727.1 - 1.3e-26 93.1 34.3 1.6e-26 92.8 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS80727.1 - 5.8e-13 48.0 30.4 7.7e-13 47.5 21.1 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 ETS80728.1 - 4.9e-19 68.1 1.1 9.9e-19 67.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS80728.1 - 5.8e-08 32.5 0.1 1.3e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like PHA_synth_III_E PF09712.5 ETS80728.1 - 0.023 14.1 0.4 0.04 13.3 0.3 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Cytokin-bind PF09265.5 ETS80728.1 - 0.066 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Methyltransf_18 PF12847.2 ETS80729.1 - 0.0001 22.8 0.1 0.00022 21.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80729.1 - 0.0029 18.0 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS80729.1 - 0.006 16.6 0.1 0.019 14.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80729.1 - 0.024 14.2 0.1 0.039 13.5 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS80729.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 ETS80729.1 - 0.11 11.5 0.1 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) COG2 PF06148.6 ETS80730.1 - 0.059 13.2 0.2 0.2 11.5 0.1 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2150 PF09920.4 ETS80730.1 - 0.13 11.8 0.1 0.63 9.6 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2150) NAD_binding_10 PF13460.1 ETS80731.1 - 6.4e-25 88.2 0.0 7.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS80731.1 - 1.2e-07 31.2 0.0 3.3e-07 29.7 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 ETS80731.1 - 0.0006 19.7 0.0 0.00085 19.3 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 ETS80731.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS80731.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 ETS80732.1 - 1.4e-43 148.9 5.2 2e-43 148.4 3.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80732.1 - 3.9e-07 29.8 7.8 8.4e-07 28.8 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPP1 PF05630.6 ETS80733.1 - 9.2e-59 198.6 3.6 1.3e-58 198.1 2.5 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Gly-zipper_OmpA PF13436.1 ETS80733.1 - 0.045 13.4 8.4 0.081 12.5 5.8 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Shadoo PF14999.1 ETS80733.1 - 0.7 9.7 8.5 0.58 10.0 4.7 1.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective p450 PF00067.17 ETS80734.1 - 2.8e-68 230.5 0.0 3.5e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 ETS80735.1 - 1.1e-11 44.2 0.5 2.9e-11 42.9 0.2 1.9 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 ETS80735.1 - 2.2e-09 36.3 6.5 0.084 12.9 0.0 7.1 7 1 1 8 8 8 2 Leucine Rich repeat F-box PF00646.28 ETS80735.1 - 1.1e-07 31.3 0.1 3.7e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 ETS80735.1 - 3.6e-07 29.3 10.3 0.81 9.9 1.7 6.8 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 ETS80735.1 - 7.8e-06 25.5 2.0 0.0011 18.6 0.3 4.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 ETS80735.1 - 2.1e-05 24.0 9.2 0.54 9.9 0.0 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 ETS80735.1 - 0.025 14.7 16.5 4.9 7.7 0.2 7.0 8 0 0 8 8 8 0 Leucine rich repeat dsrm PF00035.20 ETS80736.1 - 0.066 13.8 0.0 0.98 10.0 0.0 2.6 3 0 0 3 3 3 0 Double-stranded RNA binding motif DUF605 PF04652.11 ETS80736.1 - 2.3 7.5 12.9 2.8 7.2 9.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF2361 PF10153.4 ETS80737.1 - 6.3e-31 106.9 13.1 6.3e-31 106.9 9.1 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) CCDC-167 PF15188.1 ETS80737.1 - 0.011 15.6 2.3 0.011 15.6 1.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3091 PF11291.3 ETS80737.1 - 0.028 14.3 1.5 0.077 12.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) V_ATPase_I PF01496.14 ETS80737.1 - 0.13 10.1 5.4 0.15 9.8 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3490 PF11995.3 ETS80737.1 - 1.3 8.5 5.8 0.31 10.5 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) TPR_19 PF14559.1 ETS80738.1 - 0.037 14.3 0.2 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HCV_NS5a PF01506.14 ETS80738.1 - 0.89 9.2 5.9 2.3 7.9 4.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor CsbD PF05532.7 ETS80739.1 - 1.3e-08 34.3 7.5 0.00041 19.9 0.4 2.3 1 1 1 2 2 2 2 CsbD-like MAPEG PF01124.13 ETS80740.1 - 7.3e-20 70.8 0.2 8.5e-20 70.6 0.2 1.0 1 0 0 1 1 1 1 MAPEG family BCNT PF07572.7 ETS80741.1 - 1.9e-26 91.7 2.0 3.7e-26 90.8 1.4 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.9 ETS80741.1 - 4.2 5.2 14.0 8.8 4.2 9.7 1.5 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C2 PF00648.16 ETS80742.1 - 1.8e-58 197.8 4.2 1.3e-39 135.9 0.6 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Spatacsin_C PF14649.1 ETS80742.1 - 0.25 10.1 1.1 0.41 9.4 0.7 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus EF-hand_4 PF12763.2 ETS80743.1 - 0.00069 19.3 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MAP65_ASE1 PF03999.7 ETS80744.1 - 2.1e-73 248.0 7.5 8.1e-73 246.0 5.4 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.16 ETS80744.1 - 0.022 15.0 0.5 0.022 15.0 0.3 3.9 4 1 1 5 5 5 0 Spectrin repeat Dus PF01207.12 ETS80745.1 - 5.2e-55 186.4 0.0 1.1e-54 185.4 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF849 PF05853.7 ETS80745.1 - 0.014 14.3 0.1 0.036 12.9 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Zn_clus PF00172.13 ETS80747.1 - 8.1e-09 35.2 8.2 1.3e-08 34.5 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS80748.1 - 6.7e-130 433.6 32.7 7.7e-130 433.4 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80748.1 - 5.1e-28 97.8 46.4 3.4e-20 72.0 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_LMP1 PF05297.6 ETS80748.1 - 8.6 5.1 10.2 8.8 5.1 6.1 1.6 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) T2SE PF00437.15 ETS80749.1 - 0.028 13.3 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 ETS80749.1 - 0.071 12.5 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.24 ETS80749.1 - 0.08 12.4 0.1 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.1 ETS80749.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HA2 PF04408.18 ETS80751.1 - 2.7e-05 24.1 0.1 4.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 ETS80752.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS80752.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Amido_AtzD_TrzD PF09663.5 ETS80755.1 - 7.9e-71 238.5 5.5 3.7e-70 236.3 3.8 1.8 1 1 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) HET PF06985.6 ETS80756.1 - 2.6e-19 69.7 0.0 4.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 ETS80757.1 - 1.7e-102 343.3 32.9 2e-102 343.1 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80757.1 - 1.2e-32 113.0 29.4 1.2e-32 113.0 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 ETS80758.1 - 2e-08 33.2 0.1 1.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_N PF08240.7 ETS80759.1 - 2.5e-28 98.0 0.1 5.8e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS80759.1 - 1.4e-08 34.3 0.1 3.2e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 ETS80759.1 - 2.7e-06 26.9 0.0 6.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 ETS80759.1 - 0.00095 17.7 0.2 0.004 15.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_10 PF13460.1 ETS80759.1 - 0.012 15.6 0.1 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 ETS80759.1 - 0.017 15.1 0.1 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS80759.1 - 0.034 14.5 0.2 0.21 12.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS80759.1 - 0.035 12.9 0.1 0.056 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS80759.1 - 0.055 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 ETS80759.1 - 0.057 12.4 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 ETS80759.1 - 0.066 12.0 0.3 0.11 11.3 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 ETS80759.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 ETS80759.1 - 0.1 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 ETS80759.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 ETS80759.1 - 0.13 12.8 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AP_endonuc_2 PF01261.19 ETS80760.1 - 9.3e-11 41.4 0.0 1.7e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Img2 PF05046.9 ETS80761.1 - 1.5e-13 50.8 0.1 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 ETS80762.1 - 1.5e-48 164.3 2.9 3.4e-48 163.1 2.0 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 ETS80762.1 - 6e-12 45.8 0.2 1.4e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 PCI domain Response_reg PF00072.19 ETS80763.1 - 2.7e-12 46.6 0.0 4.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain SnoaL_4 PF13577.1 ETS80764.1 - 0.0035 17.2 0.0 0.0049 16.7 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain Nol1_Nop2_Fmu PF01189.12 ETS80764.1 - 0.049 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 NOL1/NOP2/sun family ECH PF00378.15 ETS80765.1 - 8.5e-26 90.5 0.0 1e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vps51 PF08700.6 ETS80766.1 - 2e-15 56.3 0.5 1.2e-14 53.8 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 F-box PF00646.28 ETS80767.1 - 3.1e-06 26.6 0.0 1.2e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS80767.1 - 0.00018 21.1 0.0 0.0013 18.3 0.0 2.5 1 1 1 2 2 2 1 F-box-like DUF3152 PF11350.3 ETS80767.1 - 0.044 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) DUF1349 PF07081.6 ETS80768.1 - 3e-16 59.3 0.0 4.7e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Aldo_ket_red PF00248.16 ETS80769.1 - 2.9e-43 147.7 0.0 3.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 ETS80770.1 - 9.1e-40 134.0 10.4 2.7e-20 71.6 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat KH_1 PF00013.24 ETS80772.1 - 1e-37 127.5 12.3 1.9e-14 53.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 ETS80772.1 - 9.1e-30 101.7 13.4 1.1e-10 40.8 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 ETS80772.1 - 3.4e-10 39.3 8.5 0.0042 16.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETS80772.1 - 2.5e-07 30.2 5.1 0.057 13.0 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 ETS80772.1 - 0.0002 21.1 4.6 0.7 9.7 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 ETS80772.1 - 0.0058 16.0 0.3 0.97 8.8 0.0 3.1 3 0 0 3 3 3 1 dUTPase UAA PF08449.6 ETS80773.1 - 8.6e-72 241.6 6.6 3.1e-71 239.7 4.6 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 ETS80773.1 - 2.4e-09 37.2 23.5 9e-07 28.9 4.1 3.3 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 ETS80773.1 - 0.00021 21.4 23.7 0.00035 20.7 5.7 3.3 2 2 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 ETS80773.1 - 0.0013 17.9 2.2 0.22 10.6 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 ETS80773.1 - 0.005 16.5 5.8 0.005 16.5 4.0 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF2749 PF10907.3 ETS80773.1 - 0.15 11.9 0.2 33 4.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) DSPc PF00782.15 ETS80774.1 - 1e-23 83.3 0.1 1.2e-22 79.8 0.1 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS80774.1 - 0.0004 19.7 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 ETS80774.1 - 0.23 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Pkinase PF00069.20 ETS80775.1 - 1.3e-14 53.9 0.0 3.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3740 PF12548.3 ETS80775.1 - 0.0055 16.9 0.0 0.029 14.6 0.0 2.3 1 0 0 1 1 1 1 Sulfatase protein Pkinase_Tyr PF07714.12 ETS80775.1 - 0.034 13.2 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase ATP-synt_S1 PF05827.7 ETS80775.1 - 0.054 12.8 3.2 0.24 10.6 0.3 2.4 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) HET PF06985.6 ETS80777.1 - 3.3e-32 111.5 0.3 5.2e-32 110.9 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) polyprenyl_synt PF00348.12 ETS80778.1 - 5.3e-66 222.1 0.0 6.5e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 ETS80779.1 - 1.2e-47 161.2 0.6 2.9e-47 159.9 0.1 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 ETS80779.1 - 1.1e-19 69.1 3.2 0.00055 19.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80779.1 - 3.3e-15 55.4 11.9 2.5e-08 33.4 0.3 6.2 5 1 2 7 7 7 4 TPR repeat TPR_8 PF13181.1 ETS80779.1 - 5.5e-13 47.6 7.9 0.00026 20.5 0.0 6.1 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80779.1 - 5.2e-11 42.1 8.7 0.024 15.2 0.0 7.6 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80779.1 - 8.5e-11 40.9 21.8 0.25 11.3 0.0 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80779.1 - 3.8e-10 40.1 9.3 2.7e-05 24.6 0.4 6.2 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS80779.1 - 1.2e-07 31.5 21.2 0.00022 21.0 0.3 6.9 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80779.1 - 6.8e-06 25.4 7.1 0.47 10.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS80779.1 - 5.1e-05 23.0 6.2 0.33 10.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS80779.1 - 6.3e-05 23.0 11.2 0.21 11.7 0.4 6.4 5 2 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS80779.1 - 0.013 15.7 13.0 24 5.3 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80779.1 - 0.021 15.2 18.8 13 6.5 0.4 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF3856 PF12968.2 ETS80779.1 - 0.039 13.7 0.9 0.56 10.0 0.1 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.5 ETS80779.1 - 0.13 10.9 0.0 3.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2424 PF10340.4 ETS80779.1 - 0.14 10.8 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPR_17 PF13431.1 ETS80779.1 - 0.8 10.0 7.7 2.5 8.4 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 ETS80779.1 - 1.3 8.0 12.9 0.35 9.8 1.5 4.1 4 1 0 5 5 5 0 Tetratricopeptide repeat Tweety PF04906.8 ETS80780.1 - 0.015 13.7 0.4 0.019 13.3 0.3 1.1 1 0 0 1 1 1 0 Tweety Ank_2 PF12796.2 ETS80782.1 - 2.5e-33 114.2 0.0 1.9e-10 40.9 0.0 5.8 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80782.1 - 3.4e-29 99.1 5.1 1.8e-05 24.2 0.1 8.6 8 1 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 ETS80782.1 - 9.8e-23 77.9 8.4 2.7e-06 27.0 0.1 8.9 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 ETS80782.1 - 7e-22 76.9 6.8 0.00021 21.4 0.0 7.1 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS80782.1 - 7.7e-22 77.2 11.7 4.5e-06 27.0 0.2 7.5 6 3 1 7 7 7 3 Ankyrin repeats (many copies) F-box PF00646.28 ETS80782.1 - 0.0012 18.3 1.2 0.0084 15.7 0.2 2.4 2 0 0 2 2 2 1 F-box domain DUF4142 PF13628.1 ETS80782.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) F-box-like PF12937.2 ETS80782.1 - 0.068 12.9 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like Septin PF00735.13 ETS80783.1 - 9.4e-113 375.9 0.4 1.3e-112 375.3 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 ETS80783.1 - 2.2e-06 27.6 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 ETS80783.1 - 9e-06 25.2 0.3 0.00032 20.2 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 ETS80783.1 - 9.9e-05 21.5 0.0 0.00025 20.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS80783.1 - 0.011 15.8 0.6 0.035 14.2 0.0 2.1 2 2 0 2 2 2 0 AAA domain Miro PF08477.8 ETS80783.1 - 0.012 16.1 0.8 0.034 14.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 ETS80783.1 - 0.022 14.3 0.1 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 ETS80783.1 - 0.035 13.4 0.4 0.11 11.9 0.3 1.8 1 1 0 1 1 1 0 Ras family AIG1 PF04548.11 ETS80783.1 - 0.059 12.4 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 AIG1 family DUF2968 PF11180.3 ETS80783.1 - 0.065 12.6 6.8 0.16 11.3 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_16 PF13191.1 ETS80783.1 - 0.13 12.2 2.2 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 ETS80783.1 - 0.14 11.6 0.5 8 5.9 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 ETS80783.1 - 0.15 11.5 1.1 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Val_tRNA-synt_C PF10458.4 ETS80783.1 - 0.26 11.3 5.6 0.11 12.5 0.8 2.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Dynamin_N PF00350.18 ETS80783.1 - 0.33 10.7 8.1 0.57 9.9 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Atg14 PF10186.4 ETS80783.1 - 0.77 8.6 7.2 1.7 7.4 5.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L6e PF01159.14 ETS80783.1 - 0.99 9.6 5.5 3.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein L6e Myc-LZ PF02344.10 ETS80783.1 - 3.5 7.3 11.5 0.85 9.2 2.8 2.9 2 1 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 ETS80783.1 - 5.2 7.3 19.3 1.1e+02 3.0 13.4 2.1 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 ETS80784.1 - 2e-46 157.4 0.1 3.5e-46 156.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETS80784.1 - 7e-11 41.8 0.0 4.3e-09 36.0 0.0 3.1 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS80784.1 - 0.0016 18.0 0.0 0.0056 16.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 ETS80784.1 - 0.024 14.3 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 ETS80785.1 - 1.4e-79 266.8 0.0 1.3e-77 260.4 0.0 2.6 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 ETS80785.1 - 1.3e-67 227.3 7.9 5.7e-66 221.9 0.6 3.9 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 ETS80785.1 - 1e-51 175.6 0.5 1.8e-51 174.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS80785.1 - 2.5e-27 96.1 0.0 5.1e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 ETS80785.1 - 3.4e-10 40.2 0.7 2.4e-09 37.4 0.0 2.7 3 0 0 3 3 3 1 MATH domain Tim17 PF02466.14 ETS80786.1 - 4.4e-47 159.3 12.5 5.6e-47 158.9 8.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3592 PF12158.3 ETS80786.1 - 0.12 12.2 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF543 PF04418.7 ETS80786.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Fork_head_N PF08430.7 ETS80786.1 - 4.9 7.5 10.4 2.7 8.4 5.5 1.9 1 1 1 2 2 2 0 Forkhead N-terminal region Glyco_hydro_16 PF00722.16 ETS80787.1 - 3.7e-12 45.9 0.1 9.4e-12 44.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKIP_SNW PF02731.10 ETS80788.1 - 1e-66 223.2 5.9 1e-66 223.2 4.1 2.5 2 0 0 2 2 2 1 SKIP/SNW domain DUF4603 PF15376.1 ETS80788.1 - 0.24 8.5 13.0 0.33 8.0 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) EMP24_GP25L PF01105.19 ETS80789.1 - 3.2e-45 154.1 1.0 3.6e-45 153.9 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.5 ETS80790.1 - 2.1e-63 214.4 0.0 2.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PMP1_2 PF08114.6 ETS80790.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase proteolipid family TMEM154 PF15102.1 ETS80792.1 - 0.0011 18.7 0.8 0.0019 17.9 0.5 1.3 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.6 ETS80792.1 - 0.0012 18.4 0.4 0.0017 17.9 0.3 1.2 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.1 ETS80792.1 - 0.0024 18.2 0.1 0.0082 16.5 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.4 ETS80792.1 - 0.019 14.4 1.2 0.042 13.2 0.0 2.2 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.7 ETS80792.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Plasmodium_Vir PF05795.6 ETS80792.1 - 0.075 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sarcoglycan_2 PF05510.8 ETS80792.1 - 0.12 10.6 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF347 PF03988.7 ETS80792.1 - 0.37 10.7 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) UPF0560 PF10577.4 ETS80792.1 - 8.3 4.5 8.0 0.29 9.3 0.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0560 HET PF06985.6 ETS80793.1 - 1.3e-23 83.6 0.1 2.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TauD PF02668.11 ETS80794.1 - 8.5e-33 114.1 0.0 1.8e-32 113.0 0.0 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 ETS80794.1 - 0.058 13.9 0.9 0.32 11.5 0.6 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 ETS80795.1 - 7.4e-43 146.2 0.7 1.4e-42 145.4 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyclase PF04199.8 ETS80796.1 - 1.5e-12 47.5 0.1 2.3e-12 46.9 0.1 1.4 1 1 0 1 1 1 1 Putative cyclase DIOX_N PF14226.1 ETS80797.1 - 2e-23 83.0 0.0 3.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS80797.1 - 1.6e-20 73.1 0.0 2.7e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HA2 PF04408.18 ETS80799.1 - 1.3e-19 70.1 2.1 1.4e-19 70.0 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS80799.1 - 8.8e-13 47.9 0.0 2.8e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 ETS80799.1 - 1.2e-10 41.1 0.0 3.7e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 ETS80799.1 - 1.4e-09 37.6 0.3 6.6e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS80799.1 - 0.00065 19.8 0.6 0.0025 17.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 ETS80799.1 - 0.0032 17.3 3.7 0.55 10.0 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_23 PF13476.1 ETS80799.1 - 0.0061 16.8 0.0 0.0061 16.8 0.0 4.2 4 1 0 4 4 4 1 AAA domain T2SE PF00437.15 ETS80799.1 - 0.0065 15.4 0.0 0.017 14.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 ETS80799.1 - 0.029 13.5 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 ETS80799.1 - 0.032 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 ETS80799.1 - 0.11 12.4 0.1 0.95 9.3 0.0 2.6 1 1 0 1 1 1 0 AAA domain Med6 PF04934.9 ETS80800.1 - 1.5e-41 141.2 0.0 2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.4 ETS80801.1 - 3.7e-30 103.7 2.6 3.7e-30 103.7 1.8 2.5 2 0 0 2 2 2 1 Kinase phosphorylation protein CDC27 PF09507.5 ETS80801.1 - 0.002 17.4 9.9 0.0025 17.0 6.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF3684 PF12449.3 ETS80802.1 - 0 1363.1 0.0 0 1362.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 ETS80802.1 - 9.7e-06 25.2 0.0 2.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_3 PF01494.14 ETS80803.1 - 2.1e-17 63.2 0.4 4e-16 59.0 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain FARP PF01581.11 ETS80804.1 - 0.055 13.7 0.6 49 4.9 0.1 3.4 3 0 0 3 3 3 0 FMRFamide related peptide family Gloverin PF10793.4 ETS80804.1 - 0.32 10.6 10.9 1.5 8.4 1.7 2.9 1 1 2 3 3 3 0 Gloverin-like protein NOA36 PF06524.7 ETS80804.1 - 1.9 7.6 7.4 2 7.6 5.1 1.0 1 0 0 1 1 1 0 NOA36 protein GTPase_Cys_C PF12631.2 ETS80805.1 - 5.7e-22 77.9 2.7 1.8e-20 73.1 0.2 3.2 3 0 0 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE TrmE_N PF10396.4 ETS80805.1 - 4.1e-20 71.8 0.0 1.3e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 ETS80805.1 - 8.9e-20 70.7 0.0 3.2e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS80805.1 - 9.1e-07 28.2 0.0 2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 ETS80805.1 - 8.4e-05 22.4 0.0 0.00042 20.1 0.0 2.0 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 ETS80805.1 - 0.00042 20.8 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 ETS80805.1 - 0.001 18.3 0.0 0.0029 16.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETS80805.1 - 0.017 15.4 0.7 0.09 13.0 0.1 2.5 1 1 1 2 2 2 0 ABC transporter AIG1 PF04548.11 ETS80805.1 - 0.04 13.0 0.1 0.11 11.6 0.0 1.8 1 1 0 1 1 1 0 AIG1 family AAA_25 PF13481.1 ETS80805.1 - 0.052 12.9 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS80805.1 - 0.11 12.1 0.1 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 ETS80805.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain ENOD93 PF03386.9 ETS80805.1 - 0.16 11.6 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Ribosomal_L28e PF01778.12 ETS80806.1 - 1.1e-32 112.8 2.2 2.6e-32 111.6 1.5 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 ETS80806.1 - 1.1e-20 73.6 44.6 2e-20 72.7 22.0 3.5 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 ETS80806.1 - 0.0068 14.8 27.2 0.0082 14.5 18.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 ETS80806.1 - 0.034 12.0 35.5 0.046 11.6 24.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETS80806.1 - 0.2 10.8 18.1 0.26 10.5 12.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Herpes_DNAp_acc PF04929.7 ETS80806.1 - 0.5 9.2 5.8 0.9 8.4 4.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 ETS80806.1 - 2.1 6.2 20.9 3.4 5.5 14.5 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 ETS80806.1 - 2.4 7.1 30.8 3.4 6.6 21.4 1.3 1 1 0 1 1 1 0 BUD22 Mso1_Sec1_bdg PF14475.1 ETS80807.1 - 1.1e-18 66.2 0.0 1.8e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.13 ETS80808.1 - 2.4e-34 118.6 4.1 6.2e-34 117.3 2.9 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 ETS80808.1 - 3.2e-11 42.9 0.0 0.00013 21.2 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function (DUF3548) Glyco_hydro_63 PF03200.11 ETS80809.1 - 7.2e-238 791.4 1.6 8.4e-237 787.9 1.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 ETS80809.1 - 0.01 14.5 0.1 0.018 13.6 0.0 1.4 1 0 0 1 1 1 1 Trehalase DUF1777 PF08648.7 ETS80810.1 - 5.4e-26 91.4 50.2 5.4e-26 91.4 34.8 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) p450 PF00067.17 ETS80811.1 - 5.4e-66 222.9 0.0 7e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_C PF05199.8 ETS80812.1 - 1.1e-29 103.5 0.2 1.8e-29 102.8 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS80812.1 - 8.3e-29 100.6 0.0 1.9e-26 92.9 0.0 2.7 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS80812.1 - 0.0004 20.3 0.0 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS80812.1 - 0.00071 19.5 0.4 0.0019 18.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS80812.1 - 0.0039 16.1 0.6 0.012 14.5 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS80812.1 - 0.012 14.6 0.0 0.028 13.3 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS80812.1 - 0.012 14.5 0.4 0.033 13.0 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS80812.1 - 0.015 15.3 0.0 0.86 9.6 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS80812.1 - 0.039 13.0 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS80812.1 - 0.076 11.4 0.1 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 ETS80812.1 - 0.13 11.6 0.3 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AAA PF00004.24 ETS80813.1 - 1.5e-18 67.2 0.0 3.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS80813.1 - 0.00031 20.8 0.5 0.0019 18.3 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 ETS80813.1 - 0.00072 20.3 0.1 0.0072 17.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 ETS80813.1 - 0.0014 18.1 1.2 0.1 12.0 0.1 2.4 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_18 PF13238.1 ETS80813.1 - 0.0015 18.7 0.0 0.0046 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS80813.1 - 0.0022 17.6 0.1 0.0093 15.6 0.1 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS80813.1 - 0.018 15.0 0.7 0.066 13.1 0.5 2.0 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 ETS80813.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS80813.1 - 0.06 12.7 0.4 0.2 11.0 0.3 1.9 2 1 0 2 2 2 0 AAA domain P53_TAD PF08563.6 ETS80813.1 - 0.079 12.0 0.0 0.23 10.5 0.0 1.8 1 0 0 1 1 1 0 P53 transactivation motif AAA_33 PF13671.1 ETS80813.1 - 0.082 12.7 0.1 0.24 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 ETS80813.1 - 0.091 12.4 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HET PF06985.6 ETS80814.1 - 7.7e-21 74.7 0.0 2.3e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS80814.1 - 0.00093 18.8 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS80814.1 - 0.0017 18.3 0.1 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS80814.1 - 0.028 14.5 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS80814.1 - 0.05 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 ETS80814.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 ETS80814.1 - 0.19 11.5 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 ETS80814.1 - 0.25 11.2 0.0 0.58 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Regulator_TrmB PF11495.3 ETS80814.1 - 0.5 9.3 0.0 0.97 8.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF3157 PF11355.3 ETS80815.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Ank_2 PF12796.2 ETS80816.1 - 3.4e-27 94.6 0.0 2e-14 53.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80816.1 - 1.5e-20 71.8 0.0 6.8e-05 22.4 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 ETS80816.1 - 1e-18 66.9 0.4 3.7e-10 39.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80816.1 - 6.7e-16 56.8 0.5 0.0082 16.2 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 ETS80816.1 - 1.7e-14 53.8 0.4 6.7e-05 23.2 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF2856 PF11043.3 ETS80816.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Ank_2 PF12796.2 ETS80817.1 - 9.1e-45 150.9 2.3 5.2e-17 61.9 0.0 3.9 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS80817.1 - 2.2e-38 128.1 15.1 5.5e-07 29.0 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETS80817.1 - 3.3e-32 110.2 4.8 3.8e-11 43.1 0.0 6.0 4 1 1 6 6 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS80817.1 - 7.1e-27 92.8 15.2 1.4e-07 31.5 0.1 8.2 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS80817.1 - 9.4e-25 84.2 4.0 8.3e-05 22.4 0.0 8.1 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.7 ETS80817.1 - 1.2e-16 60.7 0.4 1.2e-15 57.5 0.1 2.3 2 0 0 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.15 ETS80817.1 - 4.6e-07 29.0 0.1 1.7e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.1 ETS80817.1 - 8e-07 29.0 0.0 2.8e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS80817.1 - 1.9e-05 24.7 0.0 0.00013 22.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS80817.1 - 6.9e-05 22.9 0.4 0.00049 20.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 ETS80817.1 - 0.00052 20.2 0.0 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETS80817.1 - 0.00066 19.8 0.1 0.013 15.6 0.0 3.0 3 0 0 3 3 3 1 RNA helicase Sec7 PF01369.15 ETS80817.1 - 0.0015 18.2 0.6 0.013 15.1 0.1 2.2 1 1 0 2 2 2 1 Sec7 domain NB-ARC PF00931.17 ETS80817.1 - 0.0058 15.5 0.1 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 ETS80817.1 - 0.031 13.2 0.1 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 ETS80817.1 - 0.21 11.9 0.6 4.2 7.6 0.1 3.2 3 1 0 3 3 2 0 AAA domain Chorismate_bind PF00425.13 ETS80819.1 - 1.9e-65 220.7 0.0 5.7e-65 219.1 0.0 1.8 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 ETS80819.1 - 6.6e-23 81.1 0.0 7.2e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 ETS80819.1 - 1.9e-15 57.0 0.0 4.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 ETS80819.1 - 0.0047 16.3 0.1 0.2 11.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 SMC_N PF02463.14 ETS80820.1 - 7.5e-57 192.0 10.0 1.2e-55 188.1 7.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS80820.1 - 6e-28 97.2 0.1 7e-27 93.7 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS80820.1 - 1.1e-09 38.6 16.1 0.00016 21.7 0.1 4.1 3 1 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 ETS80820.1 - 1.3e-08 34.3 20.1 0.0038 16.4 1.6 5.2 4 1 2 6 6 6 5 Reovirus sigma C capsid protein AAA_29 PF13555.1 ETS80820.1 - 2.2e-08 33.4 0.0 4.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS80820.1 - 6e-07 29.9 33.5 6e-07 29.9 23.2 7.1 1 1 3 4 4 2 1 AAA domain IncA PF04156.9 ETS80820.1 - 0.00012 21.7 42.6 0.001 18.7 15.5 6.3 3 2 1 5 5 4 3 IncA protein AAA_13 PF13166.1 ETS80820.1 - 0.0023 16.4 105.4 0.025 13.0 17.1 6.7 4 2 2 6 6 6 3 AAA domain SbcCD_C PF13558.1 ETS80820.1 - 0.0026 17.6 0.0 0.017 14.9 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Laminin_II PF06009.7 ETS80820.1 - 0.003 17.3 10.3 0.003 17.3 7.2 8.1 5 3 4 9 9 9 3 Laminin Domain II Spc7 PF08317.6 ETS80820.1 - 0.089 11.4 109.7 0.0056 15.3 7.5 7.0 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.22 ETS80820.1 - 0.8 9.9 0.0 0.8 9.9 0.0 7.0 5 3 0 5 5 3 0 ABC transporter DUF2838 PF10998.3 ETS80821.1 - 1.2e-46 157.1 11.3 1.2e-46 157.1 7.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 ETS80821.1 - 0.1 11.4 2.0 0.17 10.8 1.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 ETS80821.1 - 0.21 8.8 3.9 0.29 8.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40 PF00400.27 ETS80822.1 - 8e-34 114.3 10.4 1.2e-06 28.1 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS80822.1 - 1.3e-07 31.5 0.1 0.00033 20.4 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF2414 PF10309.4 ETS80823.1 - 1e-15 57.1 0.1 1.6e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Tropomyosin PF00261.15 ETS80824.1 - 0.1 11.6 14.2 0.098 11.7 4.8 2.1 1 1 1 2 2 2 0 Tropomyosin IncA PF04156.9 ETS80824.1 - 0.22 11.0 6.6 0.42 10.1 4.6 1.3 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 ETS80824.1 - 0.23 11.3 12.2 0.57 10.0 0.1 2.4 1 1 1 2 2 2 0 Tropomyosin like Vac_Fusion PF02346.11 ETS80824.1 - 1.1 8.7 5.4 5 6.6 0.1 3.6 2 1 2 4 4 4 0 Chordopoxvirus fusion protein Myosin_tail_1 PF01576.14 ETS80824.1 - 6.3 4.3 15.8 2 6.0 4.9 2.0 1 1 1 2 2 2 0 Myosin tail SRP72 PF08492.7 ETS80825.1 - 1.1e-15 57.6 7.1 1.1e-15 57.6 4.9 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.1 ETS80825.1 - 2.1e-06 28.2 14.0 0.00052 20.6 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS80825.1 - 2e-05 24.6 5.6 0.0016 18.4 0.4 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS80825.1 - 0.0013 19.0 17.0 1.8 8.9 0.5 6.0 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80825.1 - 0.0087 15.9 12.2 3.8 7.6 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80825.1 - 0.052 14.2 18.2 21 6.0 0.0 7.9 8 2 2 10 10 10 0 Tetratricopeptide repeat Coatomer_E PF04733.9 ETS80825.1 - 0.27 10.4 4.5 0.36 9.9 1.5 2.3 2 1 0 2 2 2 0 Coatomer epsilon subunit TPR_12 PF13424.1 ETS80825.1 - 0.34 10.8 15.5 1 9.3 0.8 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80825.1 - 2.4 7.8 16.1 8.3 6.1 0.3 4.7 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 ETS80825.1 - 4.1 7.1 6.3 13 5.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.15 ETS80826.1 - 7.9e-39 133.3 0.0 1.4e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 ETS80826.1 - 0.00079 19.5 0.3 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 ETS80826.1 - 0.0064 16.6 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M14 PF00246.19 ETS80827.1 - 1.1e-62 212.2 0.1 1.5e-62 211.7 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 ETS80827.1 - 0.15 10.9 0.1 1.6 7.5 0.0 2.1 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family MAPEG PF01124.13 ETS80828.1 - 1.5e-24 86.0 1.8 1.8e-24 85.7 1.2 1.0 1 0 0 1 1 1 1 MAPEG family TFIIE_alpha PF02002.12 ETS80829.1 - 5.2e-13 48.4 0.3 1.1e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DUF3279 PF11682.3 ETS80829.1 - 0.14 11.7 1.8 3.2 7.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) CytochromB561_N PF09786.4 ETS80829.1 - 0.15 10.4 6.2 0.21 9.9 4.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_pol_lambd_f PF10391.4 ETS80830.1 - 3.1e-21 74.6 0.3 5.5e-21 73.8 0.2 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 ETS80830.1 - 2.9e-20 72.4 0.0 6.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 ETS80830.1 - 1.1e-19 69.8 0.0 2.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 ETS80830.1 - 1.5e-09 37.8 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 ETS80830.1 - 0.0015 18.6 0.0 0.044 13.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 ETS80830.1 - 0.013 15.8 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Myb_DNA-binding PF00249.26 ETS80833.1 - 3.1e-24 84.7 2.3 8.3e-13 48.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS80833.1 - 4.8e-16 58.6 3.9 2.8e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_transf_41 PF13844.1 ETS80834.1 - 2.1e-98 329.3 0.2 5.7e-51 172.9 0.0 3.2 1 1 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.23 ETS80834.1 - 2.2e-20 71.3 10.8 0.00023 20.6 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETS80834.1 - 7.8e-20 70.2 6.3 2.6e-05 23.7 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETS80834.1 - 3.7e-16 57.6 9.5 0.028 14.2 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETS80834.1 - 2.2e-11 43.5 2.8 0.00016 21.5 0.0 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS80834.1 - 6.1e-10 38.5 0.1 0.087 13.0 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS80834.1 - 2.8e-08 32.9 6.5 0.43 10.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS80834.1 - 6.8e-07 29.0 9.3 0.24 11.4 0.2 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS80834.1 - 5.8e-06 25.7 0.2 0.19 11.6 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS80834.1 - 1.4e-05 25.3 11.1 0.063 13.9 0.0 6.4 5 2 2 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS80834.1 - 1.6e-05 25.4 4.7 0.83 10.4 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS80834.1 - 0.002 18.2 1.6 0.065 13.3 0.1 3.2 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS80834.1 - 0.0026 18.0 0.9 2.2 8.7 0.1 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS80834.1 - 0.13 12.7 1.3 56 4.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 ETS80835.1 - 7.4e-14 50.9 0.1 2.6e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 ETS80835.1 - 4.4e-12 45.9 0.5 7.5e-12 45.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 ETS80836.1 - 2e-82 276.2 0.0 2.7e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS80836.1 - 1.6e-34 117.4 0.2 3.8e-34 116.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 ETS80836.1 - 1.9e-29 102.0 0.3 3.5e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 ETS80836.1 - 1.5e-16 59.6 5.8 2.9e-16 58.7 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 ETS80836.1 - 1.1e-14 53.8 0.0 2.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Dehydrin PF00257.14 ETS80837.1 - 0.0012 19.1 5.9 0.0017 18.6 4.1 1.2 1 0 0 1 1 1 1 Dehydrin SR-25 PF10500.4 ETS80837.1 - 0.0033 16.9 7.7 0.0052 16.2 5.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPX2 PF06886.6 ETS80837.1 - 0.081 13.0 4.8 0.16 12.0 3.3 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) CAML PF14963.1 ETS80837.1 - 0.84 8.9 4.3 1.2 8.4 3.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CDC45 PF02724.9 ETS80837.1 - 5.4 4.9 7.3 6.8 4.5 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Bacillus_HBL PF05791.6 ETS80838.1 - 0.11 11.8 10.2 0.49 9.7 3.5 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PRK PF00485.13 ETS80838.1 - 0.12 11.9 0.4 0.25 10.8 0.3 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TMF_DNA_bd PF12329.3 ETS80838.1 - 1.6 8.6 18.5 0.67 9.7 6.0 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding 4HBT_2 PF13279.1 ETS80839.1 - 3.5e-11 43.6 0.0 5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Sec5 PF15469.1 ETS80839.1 - 0.077 12.7 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Methyltransf_25 PF13649.1 ETS80840.1 - 2.1e-08 34.4 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS80840.1 - 3.1e-08 33.9 0.0 8.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS80840.1 - 4.5e-08 32.9 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS80840.1 - 1.1e-06 29.1 0.0 3.3e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS80840.1 - 2.1e-06 27.7 0.0 6.9e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS80840.1 - 0.00019 21.0 0.0 0.00077 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS80840.1 - 0.002 17.2 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS80840.1 - 0.0032 17.9 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS80840.1 - 0.016 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 ETS80840.1 - 0.13 13.1 0.0 0.41 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 ETS80841.1 - 3.1e-21 76.4 0.7 5.1e-21 75.7 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 ETS80841.1 - 3.1e-16 58.5 6.7 1.2e-09 37.5 0.5 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS80841.1 - 2.2e-09 36.9 5.1 7.2e-09 35.2 1.0 3.0 1 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 ETS80841.1 - 2.5e-09 35.8 6.1 0.00053 19.6 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 ETS80841.1 - 0.0016 18.3 13.1 0.018 15.1 0.5 5.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 ETS80841.1 - 0.39 10.9 0.1 0.39 10.9 0.0 4.3 6 0 0 6 6 6 0 Leucine Rich repeat TFIIA PF03153.8 ETS80841.1 - 7.7 6.2 18.1 12 5.6 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETS80841.1 - 9.5 4.3 10.8 14 3.8 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 ETS80842.1 - 1.4e-23 83.1 77.5 1.4e-17 63.5 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spherulin4 PF12138.3 ETS80843.1 - 1.8e-35 122.5 0.1 2.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Spherulation-specific family 4 Alpha_GJ PF03229.8 ETS80844.1 - 3.4 8.0 19.0 4.4 7.6 13.2 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J AAA_29 PF13555.1 ETS80845.1 - 9.2e-06 25.0 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS80845.1 - 9.6e-05 22.6 0.2 0.00029 21.1 0.0 1.8 2 1 0 2 2 2 1 ABC transporter MobB PF03205.9 ETS80845.1 - 0.00072 19.2 0.1 0.0022 17.7 0.0 1.9 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 ETS80845.1 - 0.00078 19.5 0.0 0.0079 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETS80845.1 - 0.0036 17.8 0.1 0.014 15.8 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 ETS80845.1 - 0.0038 17.5 0.0 0.0078 16.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS80845.1 - 0.0065 15.8 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 ETS80845.1 - 0.0078 16.0 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 ETS80845.1 - 0.0094 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 ETS80845.1 - 0.017 15.3 0.5 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS80845.1 - 0.033 13.6 0.2 0.075 12.4 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 ETS80845.1 - 0.034 13.0 0.1 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 ETS80845.1 - 0.043 13.2 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 ETS80845.1 - 0.047 13.6 0.0 0.21 11.5 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 ETS80845.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 ETS80845.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 ETS80846.1 - 1.1e-74 243.8 16.1 2.4e-11 43.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS80846.1 - 7.2e-09 34.3 2.4 9e-05 20.7 0.1 4.1 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS80846.1 - 3.9e-05 22.5 0.1 0.48 9.1 0.1 3.4 1 1 1 2 2 2 2 Nup133 N terminal like LisH PF08513.6 ETS80846.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 LisH CLASP_N PF12348.3 ETS80847.1 - 0.00017 21.0 0.0 0.0035 16.7 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 ETS80847.1 - 0.00067 19.5 8.0 0.7 10.1 0.1 5.7 6 0 0 6 6 6 1 HEAT repeat IncA PF04156.9 ETS80847.1 - 0.00071 19.2 2.9 0.0017 18.0 2.0 1.6 1 0 0 1 1 1 1 IncA protein Adaptin_N PF01602.15 ETS80847.1 - 0.013 13.8 0.1 1.8 6.8 0.0 2.9 2 1 0 2 2 2 0 Adaptin N terminal region APG6 PF04111.7 ETS80847.1 - 0.014 14.4 12.2 0.034 13.2 8.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_27 PF13514.1 ETS80847.1 - 0.032 11.9 14.9 0.066 10.8 9.5 1.9 2 0 0 2 2 2 0 AAA domain Mod_r PF07200.8 ETS80847.1 - 0.33 10.8 10.4 0.63 9.9 7.2 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 ETS80847.1 - 0.6 10.4 8.3 12 6.2 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF724 PF05266.9 ETS80847.1 - 4.4 6.8 8.4 2.9e+02 0.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.3 ETS80847.1 - 7.1 6.5 17.2 31 4.4 11.9 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 ETS80847.1 - 8.9 3.4 13.4 15 2.7 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Amidohydro_1 PF01979.15 ETS80848.1 - 1.2e-34 120.4 0.1 1.6e-34 120.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS80848.1 - 7.9e-20 72.0 10.9 1.3e-18 68.0 7.5 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS80848.1 - 4.7e-13 48.7 0.0 1.8e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS80848.1 - 1.1e-08 34.7 5.7 7.1e-07 28.7 0.8 2.6 2 1 0 2 2 2 2 Amidohydrolase family LGFP PF08310.6 ETS80849.1 - 0.042 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 LGFP repeat Abhydrolase_6 PF12697.2 ETS80852.1 - 6.9e-28 98.0 0.6 1e-27 97.5 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS80852.1 - 1.4e-12 47.6 0.5 7.5e-11 42.0 0.4 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS80852.1 - 1.8e-10 40.7 0.0 3.6e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS80852.1 - 1.7e-07 30.0 0.0 2.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF1100 PF06500.6 ETS80852.1 - 0.004 15.7 0.0 0.0055 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 ETS80852.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Acetyltransf_3 PF13302.1 ETS80853.1 - 7.8e-13 48.7 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS80853.1 - 1.8e-06 27.9 0.0 4.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 ETS80853.1 - 6.8e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS80853.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SAPS PF04499.10 ETS80854.1 - 7.6e-193 641.4 0.0 7.6e-193 641.4 0.0 2.8 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Abhydrolase_3 PF07859.8 ETS80855.1 - 2.2e-13 50.2 0.1 3.4e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Condensation PF00668.15 ETS80856.1 - 3.3e-84 282.2 0.1 1.1e-34 119.7 0.0 3.5 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 ETS80856.1 - 1e-35 122.9 0.0 1.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS80856.1 - 5.9e-15 55.2 0.2 0.00026 21.1 0.0 4.1 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS80856.1 - 0.022 15.6 0.1 1 10.3 0.0 3.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 ETS80857.1 - 2.3e-37 128.5 31.2 2.3e-37 128.5 21.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.14 ETS80858.1 - 1.3e-28 99.4 0.0 1.9e-18 65.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS80858.1 - 1.3e-14 54.7 0.0 3.3e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS80858.1 - 4.9e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS80858.1 - 7.3e-07 29.0 0.1 7.6e-06 25.7 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS80858.1 - 9.4e-06 24.7 0.2 0.0084 15.0 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS80858.1 - 1.4e-05 25.1 0.0 0.089 12.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS80858.1 - 4.7e-05 22.4 0.7 0.00018 20.5 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS80858.1 - 0.0015 18.8 0.2 0.012 15.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS80858.1 - 0.012 14.0 0.2 0.035 12.5 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 ETS80858.1 - 0.057 12.5 0.1 0.13 11.3 0.1 1.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 ETS80858.1 - 0.088 11.6 0.5 0.14 10.9 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 ETS80858.1 - 0.094 11.3 0.1 0.2 10.2 0.1 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Semialdhyde_dh PF01118.19 ETS80858.1 - 0.11 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS80858.1 - 0.14 12.2 0.1 1.1 9.4 0.1 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TROVE PF05731.6 ETS80859.1 - 0.012 14.4 0.5 0.013 14.2 0.3 1.1 1 0 0 1 1 1 0 TROVE domain AA_permease PF00324.16 ETS80860.1 - 8.1e-139 463.0 43.7 9.2e-139 462.8 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS80860.1 - 2.9e-36 124.9 46.8 3.9e-36 124.4 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 ETS80861.1 - 4.1e-21 74.8 1.3 7.7e-21 74.0 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS80861.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like OPT PF03169.10 ETS80862.1 - 2.4e-172 574.6 53.9 2.8e-172 574.4 37.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3818 PF12825.2 ETS80863.1 - 7.6e-36 123.4 0.1 1.2e-24 86.7 0.0 2.4 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 ETS80863.1 - 1.3e-27 96.1 0.0 2.4e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 PX-associated Metal_resist PF13801.1 ETS80863.1 - 0.053 13.5 2.5 0.56 10.2 0.3 2.7 2 1 0 2 2 2 0 Heavy-metal resistance DUF3106 PF11304.3 ETS80863.1 - 0.66 10.4 3.8 0.75 10.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Peptidase_S10 PF00450.17 ETS80864.1 - 4.2e-87 292.9 0.1 1.6e-86 291.1 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase CMD PF02627.15 ETS80865.1 - 2.3e-22 78.5 0.0 3.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family HAUS4 PF14735.1 ETS80866.1 - 0.00039 19.7 0.3 0.00078 18.8 0.2 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 DUF2315 PF10231.4 ETS80866.1 - 0.027 14.3 0.3 0.071 12.9 0.1 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Ribosomal_L28 PF00830.14 ETS80867.1 - 1.1e-15 57.2 0.4 1.8e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Trp_syntA PF00290.15 ETS80868.1 - 7.6e-95 316.3 0.0 1.3e-94 315.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 ETS80868.1 - 1.3e-44 152.6 1.3 2.3e-44 151.8 0.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.16 ETS80869.1 - 9.9e-92 307.6 0.0 1.2e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tyrosinase PF00264.15 ETS80870.1 - 3.5e-35 122.1 2.1 5.2e-35 121.6 1.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tankyrase_bdg_C PF15327.1 ETS80871.1 - 0.26 11.4 2.4 0.31 11.2 1.7 1.1 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain HD PF01966.17 ETS80872.1 - 0.0061 16.5 0.3 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 HD domain DUF608 PF04685.8 ETS80872.1 - 0.049 12.3 0.0 0.25 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF608 adh_short PF00106.20 ETS80873.1 - 8.9e-18 64.7 0.3 1.8e-17 63.7 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS80873.1 - 3.1e-08 33.5 0.3 5e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS80873.1 - 2.9e-05 23.9 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS80873.1 - 0.0038 16.6 0.1 0.0051 16.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CagA PF03507.8 ETS80873.1 - 0.055 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 CagA exotoxin DUF1674 PF07896.7 ETS80874.1 - 2.3e-17 62.9 1.4 4.9e-17 61.8 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Rxt3 PF08642.5 ETS80875.1 - 1.1e-26 93.2 0.0 3e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 ETS80875.1 - 0.00023 21.0 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 LCCL domain MFS_1 PF07690.11 ETS80876.1 - 1.4e-32 112.8 32.9 1.4e-32 112.8 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1614 PF07758.6 ETS80876.1 - 1.7 8.3 11.5 0.29 10.8 4.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) Sugar_tr PF00083.19 ETS80877.1 - 2.2e-42 145.2 29.3 3.2e-41 141.3 20.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80877.1 - 2.6e-16 59.2 36.1 1.2e-07 30.7 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OPT PF03169.10 ETS80878.1 - 5.5e-170 566.8 54.8 6.3e-170 566.6 38.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF754 PF05449.6 ETS80878.1 - 6.6 6.8 11.0 2.6 8.1 1.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF754) DUF4191 PF13829.1 ETS80878.1 - 7.3 5.6 6.1 0.93 8.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Glyco_hydro_28 PF00295.12 ETS80879.1 - 7e-49 166.5 14.2 9.4e-49 166.1 9.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.17 ETS80880.1 - 1.2e-50 172.3 0.0 1.6e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS80881.1 - 6.5e-22 77.7 25.0 6.5e-22 77.7 17.3 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily PRKCSH PF07915.8 ETS80882.1 - 4.8e-21 75.3 0.0 1.4e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 ETS80882.1 - 0.057 12.8 0.0 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DPBB_1 PF03330.13 ETS80886.1 - 4.5e-07 29.7 0.1 8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS80886.1 - 0.0056 16.3 0.6 0.0092 15.6 0.4 1.3 1 0 0 1 1 1 1 Barwin family FMN_dh PF01070.13 ETS80887.1 - 7.8e-82 274.9 0.1 5.8e-79 265.5 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS80887.1 - 0.00018 20.5 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 2 Conserved region in glutamate synthase IMPDH PF00478.20 ETS80887.1 - 0.0014 17.6 0.1 0.022 13.6 0.0 2.1 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS80887.1 - 0.0017 17.5 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS80887.1 - 0.013 14.8 0.2 1 8.5 0.0 2.5 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 ETS80887.1 - 0.023 13.6 0.1 0.45 9.4 0.0 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Trp_syntA PF00290.15 ETS80887.1 - 0.14 10.7 0.1 0.22 10.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain AP_endonuc_2 PF01261.19 ETS80888.1 - 1.1e-27 96.7 0.0 1.5e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_M85 PF13678.1 ETS80888.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease DUF4315 PF14193.1 ETS80889.1 - 0.14 12.0 1.1 23 4.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) TMF_DNA_bd PF12329.3 ETS80889.1 - 0.19 11.5 10.8 13 5.6 0.2 4.2 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 ETS80889.1 - 5.8 6.3 6.8 5.9 6.3 1.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Cutinase PF01083.17 ETS80891.1 - 2.6e-50 170.6 1.7 3.2e-50 170.3 1.2 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 ETS80891.1 - 0.0094 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PE-PPE PF08237.6 ETS80891.1 - 0.038 13.3 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.2 ETS80891.1 - 0.09 12.6 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS80891.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 ETS80891.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) adh_short PF00106.20 ETS80892.1 - 1.5e-08 34.7 0.0 3.1e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS80892.1 - 0.00035 20.2 0.1 0.0077 15.9 0.0 2.4 1 1 1 2 2 2 1 KR domain PH_4 PF15404.1 ETS80892.1 - 0.0042 16.6 0.0 0.01 15.3 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain Eno-Rase_NADH_b PF12242.3 ETS80892.1 - 0.039 13.7 2.3 0.12 12.1 0.4 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 ETS80893.1 - 1.1e-20 74.4 0.0 1.6e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS80893.1 - 1.7e-06 27.4 0.0 0.0001 21.6 0.0 2.7 3 0 0 3 3 3 1 NmrA-like family KR PF08659.5 ETS80893.1 - 0.057 13.0 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 KR domain Fungal_trans PF04082.13 ETS80894.1 - 1.6e-10 40.2 0.4 2.7e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_2 PF13532.1 ETS80895.1 - 1.3e-16 61.0 0.0 1.9e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS80895.1 - 1.5e-10 41.2 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETS80895.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Microtub_assoc PF07989.6 ETS80896.1 - 0.0026 17.5 9.5 0.0057 16.4 4.8 2.5 1 1 1 2 2 2 1 Microtubule associated Mu-like_Pro PF10123.4 ETS80896.1 - 0.13 11.6 4.5 0.27 10.6 3.1 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein V_ATPase_I PF01496.14 ETS80896.1 - 0.95 7.2 2.0 1.4 6.6 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 ETS80896.1 - 1.9 8.8 10.0 15 5.9 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4559 PF15112.1 ETS80896.1 - 4.5 6.3 7.6 7.7 5.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HhH-GPD PF00730.20 ETS80897.1 - 7.2e-11 42.3 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS80897.1 - 0.041 13.5 0.0 0.22 11.3 0.0 2.3 1 1 0 1 1 1 0 Helix-hairpin-helix motif FAD_binding_4 PF01565.18 ETS80898.1 - 8.3e-22 77.1 0.1 1.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS80898.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.8 4 0 0 4 4 4 1 Berberine and berberine like Peptidase_M28 PF04389.12 ETS80899.1 - 2.4e-32 112.0 0.1 4.8e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS80899.1 - 2.5e-07 30.3 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 ETS80899.1 - 4.1e-05 22.9 0.1 0.00014 21.2 0.0 1.9 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.9 ETS80899.1 - 5.8e-05 22.0 0.1 0.01 14.6 0.0 2.6 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase DNA_methylase PF00145.12 ETS80900.1 - 2.8e-40 138.4 0.0 3.4e-30 105.2 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.10 ETS80900.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Gon7 PF08738.5 ETS80901.1 - 5e-10 39.3 10.8 3.5e-08 33.3 7.5 2.3 1 1 0 1 1 1 1 Gon7 family Vps39_1 PF10366.4 ETS80902.1 - 5.5e-33 113.2 0.2 1.1e-31 109.0 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 ETS80902.1 - 1.7e-30 105.3 0.0 4.6e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 ETS80902.1 - 8.4e-19 68.0 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 ETS80902.1 - 3.5e-05 23.4 5.1 0.0019 17.7 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_1 PF00515.23 ETS80902.1 - 0.01 15.4 1.6 0.58 9.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS80902.1 - 0.23 11.4 1.3 25 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS80902.1 - 1.2 9.1 5.6 20 5.2 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.22 ETS80903.1 - 3.4e-50 167.7 6.5 1.8e-17 62.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 ETS80906.1 - 1.5e-99 333.6 33.0 1.8e-99 333.3 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80906.1 - 2.1e-21 76.0 43.6 2.9e-20 72.3 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 ETS80906.1 - 9e-05 21.3 0.1 0.00011 21.1 0.1 1.3 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 ETS80906.1 - 0.0011 17.4 0.6 0.0011 17.4 0.4 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein FAD_binding_3 PF01494.14 ETS80907.1 - 3.9e-17 62.3 0.3 1.1e-10 41.1 0.1 3.3 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 ETS80907.1 - 0.003 16.2 0.5 0.03 12.9 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 ETS80907.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS80907.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS80907.1 - 0.13 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain SPX PF03105.14 ETS80908.1 - 1.6e-51 175.6 0.0 3.3e-51 174.7 0.0 1.5 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 ETS80908.1 - 9e-38 130.3 38.9 1.3e-37 129.8 27.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 ETS80908.1 - 5.7e-17 61.3 51.0 5.4e-15 54.8 18.1 2.5 2 1 1 3 3 3 2 Citrate transporter DUF2207 PF09972.4 ETS80908.1 - 0.55 8.7 4.1 0.87 8.0 0.0 3.2 2 2 0 2 2 2 0 Predicted membrane protein (DUF2207) HbrB PF08539.6 ETS80909.1 - 8.1e-53 178.4 0.0 1.3e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 HbrB-like LIM_bind PF01803.11 ETS80910.1 - 1.9e-62 210.5 0.1 1.9e-62 210.5 0.0 6.1 2 1 3 6 6 6 1 LIM-domain binding protein Mem_trans PF03547.13 ETS80910.1 - 0.13 10.5 2.8 0.2 9.8 1.9 1.4 1 0 0 1 1 1 0 Membrane transport protein SKG6 PF08693.5 ETS80911.1 - 1.2e-06 27.6 0.7 3.3e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 ETS80911.1 - 9.4e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.6 ETS80911.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Rax2 PF12768.2 ETS80911.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Caps_synth PF05704.7 ETS80912.1 - 1.3e-12 47.4 0.0 2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 ETS80912.1 - 0.00026 21.3 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Atg8 PF02991.11 ETS80915.1 - 2.6e-51 171.9 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 ETS80915.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Git3 PF11710.3 ETS80918.1 - 2.7e-10 40.1 15.4 1e-09 38.2 6.7 3.0 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 ETS80918.1 - 0.00083 18.3 9.7 0.0017 17.3 6.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ni_hydr_CYTB PF01292.15 ETS80918.1 - 0.058 12.7 8.1 0.12 11.7 4.8 2.1 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Syndecan PF01034.15 ETS80918.1 - 2.9 7.6 5.5 2.7 7.7 0.1 2.7 3 0 0 3 3 3 0 Syndecan domain WD40 PF00400.27 ETS80919.1 - 7.8e-10 38.2 5.0 1.6e-05 24.6 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat PAM2 PF07145.10 ETS80919.1 - 0.00029 20.1 0.0 0.00064 19.0 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region PPTA PF01239.17 ETS80923.1 - 4.8e-35 117.4 14.5 8.2e-08 31.2 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ADH_zinc_N PF00107.21 ETS80924.1 - 5.4e-14 51.8 0.1 9.4e-14 51.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS80924.1 - 3.7e-05 24.6 0.1 0.00022 22.1 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS80924.1 - 0.00015 21.5 0.3 0.06 13.1 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain His_Phos_2 PF00328.17 ETS80925.1 - 1.6e-07 31.0 0.0 7.1e-06 25.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1902 PF08972.6 ETS80925.1 - 0.12 11.9 0.4 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Glyco_hydro_76 PF03663.9 ETS80926.1 - 9.9e-53 179.8 3.8 1.3e-52 179.3 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS80926.1 - 3.6e-05 22.9 0.0 0.00027 20.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 ETS80926.1 - 0.0065 14.7 0.0 0.35 9.0 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) DUF588 PF04535.7 ETS80927.1 - 2.3 7.7 10.3 1.3 8.5 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Oxidored_FMN PF00724.15 ETS80928.1 - 1.6e-69 234.4 0.0 1.9e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 ETS80928.1 - 0.00012 20.9 0.1 0.0013 17.6 0.0 2.3 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) PcrB PF01884.12 ETS80928.1 - 0.0022 17.2 0.7 0.0058 15.9 0.0 1.8 2 0 0 2 2 2 1 PcrB family His_biosynth PF00977.16 ETS80928.1 - 0.017 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 ETS80928.1 - 0.056 12.4 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase BCNT PF07572.7 ETS80928.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bucentaur or craniofacial development CD20 PF04103.10 ETS80929.1 - 0.0081 16.1 0.2 0.42 10.5 0.1 2.2 2 0 0 2 2 2 2 CD20-like family DUF872 PF05915.7 ETS80929.1 - 2.7 7.8 5.9 5.1 6.9 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Fer2 PF00111.22 ETS80930.1 - 6.6e-06 25.7 0.7 1.2e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MOSC PF03473.12 ETS80930.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain NAD_binding_6 PF08030.7 ETS80930.1 - 0.0055 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETS80930.1 - 0.0085 16.6 0.0 0.019 15.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS80930.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain adh_short PF00106.20 ETS80931.1 - 2.1e-18 66.7 0.0 4.8e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS80931.1 - 5.9e-11 42.5 0.0 7.7e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS80931.1 - 8.8e-10 38.5 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS80931.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS80931.1 - 0.0051 16.8 0.0 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS80931.1 - 0.029 13.0 0.1 0.046 12.4 0.1 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS80931.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 ETS80932.1 - 1.2e-29 102.9 0.0 1.9e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.23 ETS80933.1 - 0.00028 21.2 0.0 0.0011 19.2 0.0 1.9 1 1 0 1 1 1 1 SET domain DNA_pol_lambd_f PF10391.4 ETS80933.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda IcmL PF11393.3 ETS80935.1 - 0.062 13.2 0.2 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Macrophage killing protein with similarity to conjugation protein DUF1162 PF06650.7 ETS80937.1 - 6.1e-91 304.4 0.0 8.2e-87 290.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 ETS80937.1 - 4.3e-42 142.3 0.0 1.5e-41 140.6 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 ETS80937.1 - 3.7e-06 27.0 0.8 3.8e-05 23.7 0.0 3.0 4 0 0 4 4 4 1 ATG C terminal domain DUF3429 PF11911.3 ETS80938.1 - 4.6e-38 130.3 9.6 6.2e-38 129.9 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1510 PF07423.6 ETS80938.1 - 0.0026 17.1 27.2 0.0048 16.2 18.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 ETS80938.1 - 0.1 10.8 0.3 0.15 10.2 0.2 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF2881 PF11087.3 ETS80938.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) Ycf1 PF05758.7 ETS80938.1 - 2.7 5.5 19.9 3.3 5.3 13.8 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 ETS80938.1 - 2.9 7.4 7.0 6.1 6.4 4.8 1.5 1 0 0 1 1 1 0 IncA protein DUF908 PF06012.7 ETS80938.1 - 4.2 6.5 7.9 11 5.2 1.8 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Glycos_transf_1 PF00534.15 ETS80940.1 - 2.2e-20 72.7 0.0 4.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS80940.1 - 2.6e-11 43.7 0.0 5.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETS80940.1 - 4.1e-05 23.7 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 ETS80940.1 - 0.068 11.6 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Globin PF00042.17 ETS80941.1 - 2e-08 34.5 0.0 3.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 ETS80941.1 - 3.4e-08 34.0 0.0 5.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS80941.1 - 3.5e-08 33.4 0.0 7.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 ETS80941.1 - 0.0017 18.0 0.0 0.0056 16.3 0.0 1.8 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 ETS80941.1 - 0.011 15.6 0.2 0.042 13.7 0.1 2.1 2 1 1 3 3 3 0 Ferric reductase NAD binding domain ketoacyl-synt PF00109.21 ETS80942.1 - 2.9e-75 253.0 0.0 1.7e-74 250.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS80942.1 - 1.3e-49 169.2 0.1 2.3e-49 168.4 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 ETS80942.1 - 3.4e-46 157.2 0.0 1e-45 155.6 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS80942.1 - 2.1e-43 148.5 0.0 3.2e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS80942.1 - 3.2e-42 144.2 0.0 9.5e-42 142.7 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS80942.1 - 1.3e-32 112.0 0.0 5.1e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 ETS80942.1 - 0.0004 20.5 0.0 0.0015 18.7 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS80942.1 - 0.0024 16.8 0.0 0.0064 15.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sod_Fe_C PF02777.13 ETS80943.1 - 1.9e-40 136.9 0.6 3.3e-40 136.1 0.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETS80943.1 - 7.6e-31 106.2 1.2 1.3e-30 105.4 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.6 ETS80944.1 - 1.6e-10 41.2 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein GCFC PF07842.7 ETS80945.1 - 1.2e-74 251.1 3.8 1.2e-74 251.1 2.6 2.0 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 ETS80945.1 - 3.1e-13 49.2 2.8 9.9e-13 47.6 2.0 2.0 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 ETS80945.1 - 9.3e-09 35.3 18.6 9.3e-09 35.3 12.9 3.0 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 ETS80945.1 - 1.8e-07 30.9 1.0 1.8e-07 30.9 0.7 2.9 2 1 0 2 2 2 1 DExH-box splicing factor binding site MFS_1 PF07690.11 ETS80946.1 - 2.7e-32 111.8 30.1 4.2e-32 111.2 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_C_3 PF14497.1 ETS80947.1 - 5.2e-12 46.1 0.0 7.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS80947.1 - 2.3e-07 30.7 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS80947.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS80947.1 - 0.0088 16.2 0.0 0.12 12.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2183 PF09949.4 ETS80948.1 - 1.7e-29 101.7 0.0 4.2e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) CLN3 PF02487.12 ETS80949.1 - 2.1e-105 352.8 18.6 8.4e-103 344.2 12.9 2.5 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 ETS80949.1 - 0.00023 19.9 11.4 0.00023 19.9 7.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HPP PF04982.8 ETS80950.1 - 2e-36 124.4 5.9 2e-36 124.4 4.1 1.5 2 0 0 2 2 2 1 HPP family Tannase PF07519.6 ETS80951.1 - 3.7e-105 352.3 1.0 4.8e-105 352.0 0.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 ETS80951.1 - 0.00017 21.2 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS80951.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS80951.1 - 0.032 13.4 2.9 0.023 13.9 0.6 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family SLT PF01464.15 ETS80952.1 - 8.1e-08 31.8 0.8 3.9e-07 29.5 0.6 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 ETS80952.1 - 7e-05 22.3 0.8 0.00015 21.2 0.5 1.5 1 1 0 1 1 1 1 Lysozyme-like Xan_ur_permease PF00860.15 ETS80953.1 - 9.4e-42 142.8 34.3 4.3e-32 111.0 14.1 2.2 2 0 0 2 2 2 2 Permease family Amidohydro_1 PF01979.15 ETS80954.1 - 4.1e-50 171.3 2.7 5e-50 171.0 1.9 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS80954.1 - 5.9e-17 62.6 2.8 9.5e-16 58.6 2.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS80954.1 - 2.1e-13 50.2 2.2 9.1e-12 44.8 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS80954.1 - 0.0001 22.0 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 ETS80954.1 - 0.00046 19.2 0.1 0.0013 17.7 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase PilJ PF13675.1 ETS80955.1 - 0.026 14.8 1.6 0.066 13.5 1.1 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 ETS80955.1 - 0.068 12.9 1.3 0.14 12.0 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.7 ETS80955.1 - 0.07 12.7 0.4 0.25 10.9 0.1 1.9 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF445 PF04286.7 ETS80955.1 - 0.095 12.2 3.1 0.13 11.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Ank_2 PF12796.2 ETS80956.1 - 1.4e-31 108.6 1.5 2.7e-16 59.6 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS80956.1 - 1.9e-22 77.0 3.6 1.2e-05 25.0 0.0 7.8 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.25 ETS80956.1 - 1.9e-21 74.7 9.5 1e-05 25.0 0.0 7.3 7 1 1 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 ETS80956.1 - 6.8e-19 67.8 2.6 9.6e-09 35.5 0.1 5.0 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS80956.1 - 5.2e-15 55.1 7.6 0.012 15.7 0.0 6.6 2 2 5 7 7 7 4 Ankyrin repeats (many copies) DUF4246 PF14033.1 ETS80957.1 - 8.1e-178 592.1 1.3 9.7e-178 591.8 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 ETS80957.1 - 0.039 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2264 PF10022.4 ETS80959.1 - 1.6e-114 382.3 2.9 2e-114 382.0 2.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BNR PF02012.15 ETS80959.1 - 0.027 14.2 0.3 0.13 12.1 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat MFS_1 PF07690.11 ETS80960.1 - 4.6e-27 94.6 21.4 4.6e-27 94.6 14.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 ETS80961.1 - 6.4e-07 28.7 0.1 1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Peptidase_M19 PF01244.16 ETS80962.1 - 7.9e-102 340.4 0.0 9.2e-102 340.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fungal_trans PF04082.13 ETS80963.1 - 1.2e-20 73.4 1.8 2.7e-20 72.3 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS80963.1 - 2.6e-05 24.0 7.2 4.9e-05 23.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.7 ETS80964.1 - 3.1e-07 30.3 0.3 3.1e-07 30.3 0.2 1.8 2 0 0 2 2 2 1 Cerato-platanin Aminotran_3 PF00202.16 ETS80965.1 - 4e-91 305.3 0.0 4.7e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.20 ETS80966.1 - 1.2e-61 208.1 0.0 1.5e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS80966.1 - 3.5e-29 101.6 0.0 6.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS80966.1 - 0.003 16.5 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS80966.1 - 0.018 14.8 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 ETS80967.1 - 2.9e-116 388.1 0.0 3.2e-116 387.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETS80967.1 - 0.027 13.0 0.0 0.29 9.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.17 ETS80968.1 - 2.4e-21 76.6 0.0 2.9e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.19 ETS80969.1 - 1.1e-83 281.3 16.2 1.5e-83 280.8 11.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80969.1 - 8e-25 87.2 26.6 8e-25 87.2 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SOBP PF15279.1 ETS80970.1 - 1.9 8.7 11.9 3.1 8.1 8.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein NmrA PF05368.8 ETS80971.1 - 2.2e-28 99.1 0.1 2.7e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS80971.1 - 2.3e-06 27.2 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS80971.1 - 3.3e-05 22.7 0.1 6.5e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS80971.1 - 0.00012 22.1 0.8 0.00045 20.2 0.1 2.3 3 1 0 3 3 3 1 NADH(P)-binding KR PF08659.5 ETS80971.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 ETS80971.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 ETS80971.1 - 0.096 12.9 0.0 0.33 11.2 0.0 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Arf PF00025.16 ETS80972.1 - 3.4e-75 251.1 0.2 3.9e-75 250.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETS80972.1 - 5.1e-13 48.7 0.0 5.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETS80972.1 - 1.2e-12 47.1 2.2 2.2e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 ETS80972.1 - 3.6e-12 45.8 0.0 4.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS80972.1 - 2.9e-11 42.9 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS80972.1 - 3.1e-08 34.1 0.0 4.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS80972.1 - 0.00024 21.0 0.1 0.00032 20.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DegQ PF08181.6 ETS80972.1 - 0.019 14.6 0.2 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 DegQ (SacQ) family 6PF2K PF01591.13 ETS80972.1 - 0.04 12.9 0.1 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 ETS80972.1 - 0.056 13.3 0.2 0.8 9.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 ETS80973.1 - 6.3e-125 417.2 24.0 7.2e-125 417.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS80973.1 - 2.6e-21 75.7 38.5 7e-15 54.5 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 ETS80974.1 - 9.2e-11 41.5 1.9 6.1e-09 35.5 1.3 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 ETS80975.1 - 5e-84 281.8 0.0 7.1e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS80975.1 - 2e-70 236.8 0.1 2e-69 233.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS80975.1 - 2.3e-24 85.0 0.1 5.9e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS80975.1 - 3.3e-20 72.2 0.0 5.8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF4463 PF14703.1 ETS80975.1 - 0.097 13.2 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Cation_efflux PF01545.16 ETS80976.1 - 1.3e-76 257.3 11.3 5e-76 255.4 7.8 1.7 1 1 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 ETS80976.1 - 0.016 14.1 0.7 0.016 14.1 0.5 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component PQ-loop PF04193.9 ETS80976.1 - 0.039 13.5 0.2 0.039 13.5 0.1 2.2 3 0 0 3 3 3 0 PQ loop repeat AT_hook PF02178.14 ETS80977.1 - 0.00064 19.1 2.7 1 9.2 0.6 3.5 2 0 0 2 2 2 2 AT hook motif BRCT PF00533.21 ETS80977.1 - 0.25 11.5 0.0 0.45 10.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PLA2_B PF01735.13 ETS80978.1 - 3.2e-188 625.9 1.0 3.7e-188 625.6 0.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1295 PF06966.7 ETS80981.1 - 6.2e-58 195.8 1.2 7.8e-58 195.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 ETS80981.1 - 4.7e-06 26.4 0.2 4.7e-06 26.4 0.1 2.8 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 ETS80981.1 - 1.5e-05 25.0 0.1 6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS80981.1 - 0.0011 18.9 0.1 0.0011 18.9 0.0 2.7 4 0 0 4 4 4 1 Phospholipid methyltransferase YaeQ PF07152.7 ETS80983.1 - 0.098 11.9 0.2 0.4 9.9 0.0 1.9 2 0 0 2 2 2 0 YaeQ protein Med8 PF10232.4 ETS80984.1 - 3.9e-22 78.8 3.3 5.1e-22 78.4 2.3 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TMEM171 PF15471.1 ETS80984.1 - 0.017 13.9 0.3 0.029 13.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Mito_fiss_reg PF05308.6 ETS80984.1 - 0.024 13.9 0.3 0.055 12.8 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3239 PF11580.3 ETS80984.1 - 0.04 13.9 0.1 0.04 13.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3239) Allexi_40kDa PF05549.6 ETS80984.1 - 0.18 11.0 1.3 0.28 10.4 0.7 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein COG5 PF10392.4 ETS80984.1 - 0.39 10.6 3.1 0.47 10.4 0.5 2.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4611 PF15387.1 ETS80984.1 - 0.69 10.0 9.4 7.6 6.7 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 ETS80984.1 - 2.9 8.2 16.7 6.6 7.1 2.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfatase PF00884.18 ETS80985.1 - 7e-55 186.3 0.0 8.7e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 ETS80985.1 - 1.7e-18 66.1 0.2 4.8e-18 64.7 0.1 1.8 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 ETS80985.1 - 5.5e-11 42.3 0.0 2.9e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETS80985.1 - 0.031 13.6 0.0 0.23 10.8 0.0 2.2 2 1 0 2 2 2 0 Metalloenzyme superfamily Sulfatase_C PF14707.1 ETS80985.1 - 0.14 12.4 0.9 0.41 10.9 0.5 1.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase PQ-loop PF04193.9 ETS80986.1 - 7.9e-24 82.9 7.8 1.6e-14 53.1 2.2 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3431 PF11913.3 ETS80987.1 - 1.7e-68 230.4 0.0 2.3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) HIN PF02760.10 ETS80987.1 - 0.095 12.0 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Macoilin PF09726.4 ETS80988.1 - 1.5 7.0 5.2 2.1 6.5 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp12 PF04003.7 ETS80990.1 - 0.051 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF1993 PF09351.5 ETS80990.1 - 0.16 11.8 0.7 0.54 10.1 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Gln-synt_C PF00120.19 ETS80991.1 - 1.2e-49 168.7 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 ETS80991.1 - 2.5e-20 73.1 0.0 6.3e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase RRM_1 PF00076.17 ETS80992.1 - 6.2e-23 80.2 0.0 1.9e-13 49.8 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS80992.1 - 2.9e-21 75.2 0.0 9.8e-11 41.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS80992.1 - 2.4e-08 33.6 0.1 0.0013 18.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRK PF00485.13 ETS80993.1 - 5e-07 29.4 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETS80993.1 - 6.8e-06 26.9 0.2 4.2e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS80993.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS80993.1 - 0.0015 17.7 0.1 0.0033 16.5 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 ETS80993.1 - 0.004 16.0 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 ETS80993.1 - 0.0043 16.9 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS80993.1 - 0.0045 17.1 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ETS80993.1 - 0.015 14.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.1 ETS80993.1 - 0.036 14.0 0.0 0.1 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 ETS80993.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 ETS80993.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.14 ETS80993.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 ETS80993.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRELI PF04707.9 ETS80995.1 - 3.5e-41 140.3 0.3 4.1e-41 140.1 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Pico_P2B PF01552.12 ETS80995.1 - 0.057 13.5 0.2 0.17 12.0 0.0 1.8 1 1 1 2 2 2 0 Picornavirus 2B protein GATase_3 PF07685.9 ETS80995.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Fringe PF02434.11 ETS80996.1 - 7.4e-05 22.0 2.4 0.0008 18.6 1.7 2.3 1 1 0 1 1 1 1 Fringe-like HRM PF02793.17 ETS80997.1 - 0.0057 16.6 0.8 0.0083 16.1 0.6 1.4 1 1 0 1 1 1 1 Hormone receptor domain Peptidase_M24 PF00557.19 ETS80998.1 - 2.5e-40 138.2 0.0 3.2e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 LZ_Tnp_IS66 PF13007.2 ETS80998.1 - 8.6 7.0 8.3 18 6.0 5.7 1.6 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain GFO_IDH_MocA PF01408.17 ETS80999.1 - 7.2e-21 74.9 0.0 1.7e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 ETS80999.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CorA PF01544.13 ETS81000.1 - 3.2e-05 23.1 0.2 5.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L29 PF00831.18 ETS81000.1 - 0.068 12.8 0.5 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein Tnp_P_element PF12017.3 ETS81000.1 - 0.2 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Transposase protein NPP1 PF05630.6 ETS81001.1 - 5.5e-58 196.1 0.0 6.4e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) FAD_binding_3 PF01494.14 ETS81002.1 - 3.5e-15 55.9 1.8 1.4e-14 53.9 1.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS81002.1 - 6.7e-06 26.0 0.3 2.6e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS81002.1 - 4.5e-05 23.6 0.1 0.00017 21.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS81002.1 - 6.7e-05 21.9 0.6 0.00098 18.1 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS81002.1 - 0.00097 18.9 0.2 0.17 11.6 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 ETS81002.1 - 0.0021 16.9 0.0 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 ETS81002.1 - 0.0081 16.0 0.0 0.0098 15.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS81002.1 - 0.017 13.9 0.8 0.03 13.1 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 ETS81002.1 - 0.025 13.6 0.1 0.95 8.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS81002.1 - 0.026 14.9 0.4 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS81002.1 - 0.032 12.7 0.1 0.076 11.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS81002.1 - 0.035 13.0 0.1 1 8.1 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 ETS81002.1 - 0.084 11.4 1.1 0.18 10.3 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 ETS81002.1 - 0.086 11.6 0.2 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.27 ETS81003.1 - 2.5e-26 90.5 1.0 2.5e-06 27.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 ETS81003.1 - 0.094 12.4 0.7 5.3 6.6 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Tubulin PF00091.20 ETS81005.1 - 2.3e-74 249.8 0.0 3.3e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS81005.1 - 3.7e-46 156.2 0.4 7e-46 155.3 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS81005.1 - 3.9e-08 33.3 0.0 8.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Peptidase_S6 PF02395.11 ETS81006.1 - 0.065 11.3 0.0 0.065 11.3 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease DUF768 PF05589.6 ETS81008.1 - 0.038 13.9 1.3 0.11 12.4 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Ribosomal_L17 PF01196.14 ETS81009.1 - 4.2e-31 107.3 0.1 4.2e-31 107.3 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L17 DALR_1 PF05746.10 ETS81009.1 - 0.069 13.1 1.6 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 DALR anticodon binding domain ATP-synt_B PF00430.13 ETS81009.1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.5 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF1253 PF06862.7 ETS81010.1 - 1.4e-164 547.6 0.2 1.8e-164 547.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 ETS81010.1 - 0.002 17.6 0.0 0.97 8.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Corona_I PF03187.9 ETS81010.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Corona nucleocapsid I protein Daxx PF03344.10 ETS81010.1 - 0.23 9.9 18.5 0.36 9.2 12.8 1.2 1 0 0 1 1 1 0 Daxx Family JAB PF01398.16 ETS81011.1 - 2.1e-16 59.6 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETS81011.1 - 2.4e-12 46.9 0.2 4e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cupin_2 PF07883.6 ETS81012.1 - 0.00073 18.9 0.0 0.11 12.0 0.0 2.5 1 1 0 1 1 1 1 Cupin domain CFEM PF05730.6 ETS81014.1 - 1.4e-13 50.4 13.0 1.7e-13 50.1 9.0 1.1 1 0 0 1 1 1 1 CFEM domain DUF2071 PF09844.4 ETS81014.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) Lipase_3 PF01764.20 ETS81015.1 - 3.4e-35 120.6 0.0 5.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 ETS81015.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETS81015.1 - 0.00035 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS81015.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS81015.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein MFS_1 PF07690.11 ETS81016.1 - 8.8e-40 136.4 30.2 8.8e-40 136.4 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81016.1 - 4.4e-10 38.7 9.4 4.4e-10 38.7 6.5 3.1 2 2 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 ETS81016.1 - 1.3e-05 23.6 3.7 1.9e-05 23.1 2.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.9 ETS81017.1 - 4.7e-36 124.6 0.1 6.5e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 A2M_N PF01835.14 ETS81017.1 - 0.019 15.1 0.0 0.049 13.8 0.0 1.8 1 1 0 1 1 1 0 MG2 domain NPCBM_assoc PF10633.4 ETS81017.1 - 0.023 14.7 1.2 0.59 10.2 0.0 2.9 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF1118 PF06549.7 ETS81018.1 - 0.29 11.2 1.6 0.38 10.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) CBP PF12192.3 ETS81018.1 - 2.3 8.2 16.0 0.044 13.7 5.6 2.1 1 1 1 2 2 2 0 Fungal calcium binding protein Acetyltransf_7 PF13508.1 ETS81019.1 - 1.8e-08 34.4 0.0 4.9e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS81019.1 - 1.3e-07 31.5 0.1 4.1e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS81019.1 - 2.2e-05 24.5 0.1 7.9e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS81019.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 ETS81019.1 - 0.00015 21.6 0.0 0.00074 19.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS81019.1 - 0.052 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SUZ PF12752.2 ETS81021.1 - 6.8e-13 48.9 4.2 6.8e-13 48.9 2.9 3.7 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 ETS81021.1 - 2.7e-07 30.1 0.1 6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.7 ETS81022.1 - 1.1e-44 151.9 3.6 1.1e-44 151.9 2.5 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 ETS81023.1 - 6.5e-22 77.2 0.0 2.5e-07 30.5 0.0 5.2 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 ETS81023.1 - 3.5e-13 48.5 0.0 0.0021 17.8 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 ETS81023.1 - 7e-13 47.7 0.0 0.00019 21.4 0.0 5.3 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETS81023.1 - 1.2e-10 40.6 0.0 6.6e-05 22.2 0.0 4.5 4 0 0 4 4 4 2 PPR repeat Ank_4 PF13637.1 ETS81023.1 - 0.096 13.2 0.1 4.5 7.8 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Fungal_trans PF04082.13 ETS81024.1 - 2.2e-19 69.3 1.2 5.2e-19 68.1 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81024.1 - 1e-08 34.8 9.0 2.2e-08 33.8 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 ETS81025.1 - 6.2e-13 48.4 0.2 1.6e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 ETS81025.1 - 2e-06 27.9 0.1 3.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 ETS81025.1 - 3.8e-06 26.6 0.1 9e-05 22.2 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 ETS81025.1 - 5.8e-05 22.4 0.1 0.0001 21.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 ETS81025.1 - 0.029 14.2 0.9 0.055 13.3 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF1153 PF06627.6 ETS81025.1 - 0.12 12.2 0.2 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Hexapep PF00132.19 ETS81026.1 - 1.9e-14 52.4 10.3 6.4e-08 31.7 1.0 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS81026.1 - 8e-14 50.9 12.1 1e-07 31.3 0.9 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 ETS81026.1 - 4.9e-12 45.6 0.1 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 ETS81026.1 - 8.6e-10 38.3 8.0 1.7e-09 37.3 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 ETS81027.1 - 1.5e-25 89.9 0.0 3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS81027.1 - 8.9e-19 67.6 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldo_ket_red PF00248.16 ETS81029.1 - 1.1e-51 175.3 0.0 1.3e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRRNT_2 PF08263.7 ETS81030.1 - 0.038 13.9 0.7 0.038 13.9 0.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Lamprin PF06403.6 ETS81030.1 - 0.47 10.2 2.8 0.78 9.4 1.9 1.6 1 1 0 1 1 1 0 Lamprin Pkinase PF00069.20 ETS81031.1 - 7.8e-36 123.5 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81031.1 - 1.6e-14 53.6 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS81031.1 - 0.014 15.1 0.0 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 ETS81032.1 - 8.5e-52 175.5 0.0 9.6e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Shugoshin_N PF07558.6 ETS81032.1 - 0.082 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PEPCK_ATP PF01293.15 ETS81032.1 - 0.12 10.8 0.3 3 6.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Secretin_N PF03958.12 ETS81033.1 - 0.28 11.4 5.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain Neurensin PF14927.1 ETS81036.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Neurensin Pox_LP_H2 PF03356.10 ETS81036.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Viral late protein H2 Beta-lactamase PF00144.19 ETS81037.1 - 8.2e-64 215.6 0.0 9.7e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase S4 PF01479.20 ETS81037.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 S4 domain LCM PF04072.9 ETS81038.1 - 3.9e-32 111.2 0.0 5.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase AIM24 PF01987.12 ETS81039.1 - 2.1e-49 167.8 0.1 2.6e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Med1 PF10744.4 ETS81040.1 - 6e-33 114.1 0.0 1.8e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 BTB PF00651.26 ETS81042.1 - 0.00037 20.4 0.1 0.0073 16.2 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain SCRG1 PF15224.1 ETS81042.1 - 0.072 12.9 7.9 0.53 10.1 0.1 2.6 2 0 0 2 2 2 0 Scrapie-responsive protein 1 BTB PF00651.26 ETS81043.1 - 0.013 15.5 0.1 0.046 13.7 0.0 1.9 2 1 0 2 2 2 0 BTB/POZ domain CRAL_TRIO_N PF03765.10 ETS81043.1 - 0.087 12.9 0.2 0.43 10.7 0.1 2.1 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain MRC1 PF09444.5 ETS81045.1 - 1.1e-37 129.5 16.4 1.1e-37 129.5 11.4 7.2 6 1 1 7 7 7 1 MRC1-like domain SAGA-Tad1 PF12767.2 ETS81046.1 - 1e-57 195.7 0.0 1.3e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 ETS81048.1 - 5.7e-121 404.4 0.1 7.4e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 ETS81049.1 - 3.9e-45 154.0 0.0 1.2e-44 152.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81049.1 - 1.9e-24 86.1 0.0 5.9e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS81049.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.11 ETS81050.1 - 3.7e-39 134.4 43.8 3.7e-39 134.4 30.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81050.1 - 1.3e-05 23.9 36.2 7.6e-05 21.4 25.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Jiraiya PF15038.1 ETS81050.1 - 0.012 14.9 1.2 0.012 14.9 0.8 3.5 4 0 0 4 4 4 0 Jiraiya SAYSvFN PF10260.4 ETS81050.1 - 3.5 7.4 5.9 6.2 6.6 1.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Fungal_trans PF04082.13 ETS81051.1 - 2.4e-16 59.4 0.0 5.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81051.1 - 2.7e-06 27.1 10.2 6e-06 26.0 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Spc34 PF08657.5 ETS81051.1 - 0.033 13.8 1.0 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 Dickkopf_N PF04706.7 ETS81051.1 - 0.85 9.8 8.5 1.8 8.7 5.9 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region CBM_4_9 PF02018.12 ETS81052.1 - 3.5e-05 23.8 0.4 3.5e-05 23.8 0.3 1.9 2 1 0 2 2 2 1 Carbohydrate binding domain DUF515 PF04415.7 ETS81052.1 - 4.7 5.3 7.1 8.4 4.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) adh_short PF00106.20 ETS81053.1 - 4.9e-22 78.6 0.2 1.9e-21 76.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81053.1 - 1.2e-09 38.0 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS81053.1 - 2.3e-05 24.2 0.1 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS81053.1 - 3.7e-05 23.2 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS81053.1 - 0.00086 19.0 0.1 0.0024 17.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ETS81053.1 - 0.036 12.9 0.3 0.05 12.4 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS81053.1 - 0.077 12.9 0.2 0.25 11.3 0.1 1.9 2 1 0 2 2 2 0 NADH(P)-binding Peptidase_M36 PF02128.10 ETS81054.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) DUF2231 PF09990.4 ETS81055.1 - 0.01 16.1 2.5 0.01 16.1 1.7 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) HsbA PF12296.3 ETS81056.1 - 7.5e-12 45.1 2.3 1.6e-11 44.1 1.6 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Lipase_GDSL_2 PF13472.1 ETS81056.1 - 0.11 12.6 1.7 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Tyrosinase PF00264.15 ETS81057.1 - 1.7e-41 142.8 0.0 2.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.5 ETS81057.1 - 0.091 13.1 0.1 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain FAD_binding_4 PF01565.18 ETS81059.1 - 1.1e-18 67.0 2.6 2.2e-18 66.0 1.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS81059.1 - 1.2e-10 41.0 0.1 2.8e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like F-box PF00646.28 ETS81060.1 - 5.6e-05 22.6 0.0 0.00014 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS81060.1 - 0.00054 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Bys1 PF04681.7 ETS81061.1 - 0.088 12.5 0.4 0.23 11.1 0.1 1.7 1 1 1 2 2 2 0 Blastomyces yeast-phase-specific protein FA_hydroxylase PF04116.8 ETS81061.1 - 0.4 11.0 2.5 0.57 10.5 1.7 1.3 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily Y_phosphatase3 PF13350.1 ETS81062.1 - 8.7e-39 133.3 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 ETS81062.1 - 3.5e-07 30.2 0.0 7e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 ETS81062.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 ETS81062.1 - 0.047 13.0 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Amidohydro_3 PF07969.6 ETS81063.1 - 5.7e-58 197.0 0.0 6.7e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 ETS81063.1 - 0.031 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase family Amidohydro_5 PF13594.1 ETS81063.1 - 0.073 12.8 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Amidohydrolase DUF834 PF05754.9 ETS81064.1 - 0.31 10.8 2.2 0.47 10.2 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF834) FSH1 PF03959.8 ETS81065.1 - 7.5e-26 90.8 0.0 1.1e-25 90.3 0.0 1.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 ETS81065.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 ETS81066.1 - 1.2e-73 247.6 0.0 3e-73 246.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS81066.1 - 2.2e-70 237.5 0.0 3.8e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 ETS81066.1 - 1.5e-63 213.7 3.7 6.7e-63 211.6 2.5 2.2 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS81066.1 - 1.8e-53 181.6 0.3 4.2e-53 180.4 0.2 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS81066.1 - 1.8e-51 174.3 2.4 1.8e-51 174.3 1.6 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS81066.1 - 3.8e-40 136.4 0.4 1.1e-39 134.9 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS81066.1 - 7e-20 70.8 0.3 3.2e-19 68.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS81066.1 - 6.7e-14 52.8 0.1 5.5e-13 49.9 0.0 2.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS81066.1 - 1.2e-08 34.6 0.0 4.5e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS81066.1 - 1.3e-06 28.5 1.0 9.5e-06 25.7 0.1 2.9 3 0 0 3 3 3 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 ETS81066.1 - 0.0008 19.0 0.2 0.006 16.2 0.1 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 ETS81066.1 - 0.0013 17.7 0.3 0.0024 16.8 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 ETS81066.1 - 0.0042 16.1 0.0 0.0097 14.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 ETS81066.1 - 0.006 16.6 0.2 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 ETS81066.1 - 0.031 14.2 3.3 4.2 7.3 0.1 3.0 2 1 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 ETS81066.1 - 0.1 11.9 0.5 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 ETS81067.1 - 2.1e-08 33.9 16.6 3.5e-08 33.2 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 ETS81068.1 - 8.8e-20 71.2 0.0 1.3e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81068.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS81068.1 - 9.5e-08 32.0 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS81068.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS81068.1 - 0.014 14.6 0.1 0.035 13.3 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.1 ETS81069.1 - 1.5e-19 70.7 0.5 7.8e-12 45.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS81069.1 - 2.5e-09 37.2 1.7 2.7e-08 33.9 1.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS81069.1 - 0.00033 20.3 2.1 0.00045 19.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 ETS81069.1 - 0.0018 17.9 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 ETS81069.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 ETS81069.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.14 ETS81069.1 - 0.051 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_10 PF13460.1 ETS81069.1 - 0.16 11.9 0.5 0.39 10.6 0.3 1.8 1 1 1 2 2 2 0 NADH(P)-binding SNF2_N PF00176.18 ETS81070.1 - 2.2e-82 276.2 0.2 2.2e-82 276.2 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 ETS81070.1 - 1.8e-42 143.8 4.0 4e-42 142.6 2.0 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 ETS81070.1 - 3.3e-33 114.4 6.7 3.3e-33 114.4 4.7 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 ETS81070.1 - 7.5e-15 54.5 0.0 2.4e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS81070.1 - 8.8e-09 35.4 0.7 3.4e-07 30.2 0.0 3.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS81070.1 - 2.2e-05 24.0 0.0 5.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 ETS81070.1 - 0.00014 21.8 0.1 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 ETS81070.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 ETS81070.1 - 0.023 14.5 0.5 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.1 ETS81071.1 - 1.9e-09 37.8 0.6 3e-09 37.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) tRNA_SAD PF07973.9 ETS81072.1 - 1.4e-06 28.1 0.4 2.5e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 ETS81072.1 - 4.1e-05 22.0 0.0 8.9e-05 20.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) Ank_2 PF12796.2 ETS81073.1 - 7.1e-36 122.4 0.1 9.7e-12 45.0 0.0 5.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS81073.1 - 6.3e-33 112.5 0.7 1.9e-09 37.7 0.0 7.5 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81073.1 - 4.9e-27 93.3 0.3 1.9e-07 31.0 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 ETS81073.1 - 3.8e-26 89.5 0.0 5.5e-05 22.7 0.0 8.0 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 ETS81073.1 - 4e-25 85.3 0.0 1.1e-05 25.1 0.0 8.6 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.7 ETS81073.1 - 8.3e-10 38.5 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS81073.1 - 5.7e-05 23.2 0.1 0.00031 20.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 ETS81073.1 - 0.0012 17.9 5.8 0.064 12.2 0.1 2.6 2 1 0 3 3 3 2 KAP family P-loop domain RNA_helicase PF00910.17 ETS81073.1 - 0.003 17.7 0.0 0.0086 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 ETS81073.1 - 0.0035 17.6 0.0 0.015 15.5 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_16 PF13191.1 ETS81073.1 - 0.011 15.7 0.1 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 ETS81073.1 - 0.014 14.8 0.4 0.071 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA-like domain AFG1_ATPase PF03969.11 ETS81073.1 - 0.015 14.0 0.0 0.039 12.7 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase KaiC PF06745.8 ETS81073.1 - 0.016 14.3 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 ETS81073.1 - 0.027 13.5 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 ETS81073.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETS81073.1 - 0.043 13.6 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS81073.1 - 0.058 14.2 0.1 0.26 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS81073.1 - 0.086 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 ETS81073.1 - 0.088 11.5 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein PNP_UDP_1 PF01048.15 ETS81074.1 - 2.7e-13 49.4 0.0 9.5e-13 47.6 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_3 PF01757.17 ETS81075.1 - 1.1e-45 155.9 36.5 1.8e-45 155.2 25.3 1.3 1 0 0 1 1 1 1 Acyltransferase family Acyl-CoA_dh_1 PF00441.19 ETS81076.1 - 2.1e-29 102.5 1.3 3.2e-29 101.9 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS81076.1 - 4.8e-20 70.8 2.1 9.4e-20 69.8 1.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS81076.1 - 7.3e-18 65.1 0.0 1.8e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS81076.1 - 0.0016 18.6 0.1 0.0032 17.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF605 PF04652.11 ETS81078.1 - 8.4 5.6 15.7 11 5.2 10.9 1.2 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 ETS81079.1 - 1.5e-63 214.9 0.0 2.1e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 ETS81080.1 - 0.0035 16.0 0.0 0.021 13.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 ETS81081.1 - 8.1e-07 27.9 0.2 6.3e-06 25.0 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_1 PF00667.15 ETS81082.1 - 7.7e-48 162.8 0.0 1.2e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 ETS81082.1 - 1.3e-29 103.0 0.1 3.6e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 ETS81082.1 - 1.7e-19 70.3 0.0 1.3e-18 67.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain bact-PGI_C PF10432.4 ETS81082.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Dfp1_Him1_M PF08630.5 ETS81082.1 - 0.09 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region Chitin_synth_1 PF01644.12 ETS81083.1 - 1.3e-80 268.9 0.1 2e-80 268.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 ETS81083.1 - 3.7e-33 113.0 0.0 6.7e-33 112.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 ETS81083.1 - 1.4e-23 83.1 1.6 6.9e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 ETS81083.1 - 2.3e-07 30.8 0.0 7.5e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 ETS81083.1 - 8.4e-06 25.6 14.2 8.4e-06 25.6 9.8 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF2457 PF10446.4 ETS81084.1 - 0.13 10.9 21.6 0.13 11.0 15.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SspB PF04386.8 ETS81084.1 - 0.91 9.1 4.4 1 8.9 3.0 1.0 1 0 0 1 1 1 0 Stringent starvation protein B CENP-B_dimeris PF09026.5 ETS81084.1 - 1.6 9.0 21.8 1.9 8.7 15.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 ETS81084.1 - 2.3 6.1 16.2 2.3 6.1 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 ETS81084.1 - 2.4 7.9 9.2 3.1 7.5 6.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETS81084.1 - 2.4 7.7 13.6 2.5 7.6 9.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 ETS81084.1 - 2.4 8.1 6.5 2.5 8.0 4.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 ETS81084.1 - 2.9 6.2 12.7 3 6.2 8.8 1.0 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 ETS81084.1 - 3 7.0 14.8 3 7.0 10.2 1.0 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 ETS81084.1 - 4.5 6.7 17.5 5.7 6.4 12.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2722 PF10846.3 ETS81084.1 - 4.6 6.1 7.2 5 6.0 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) VID27 PF08553.5 ETS81084.1 - 5.3 5.1 8.8 5.4 5.1 6.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 ETS81084.1 - 5.5 5.9 8.6 5.4 5.9 6.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 ETS81084.1 - 5.6 6.2 10.0 6.2 6.1 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 ETS81084.1 - 6.7 5.6 16.4 7.1 5.5 11.4 1.0 1 0 0 1 1 1 0 BUD22 EBV-NA3 PF05009.7 ETS81084.1 - 8 5.6 8.2 10 5.3 5.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PI3K_1B_p101 PF10486.4 ETS81084.1 - 9 3.7 8.2 9.2 3.6 5.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GMC_oxred_N PF00732.14 ETS81086.1 - 5.5e-65 219.4 0.0 7.4e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS81086.1 - 1.2e-35 122.8 0.0 2.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS81086.1 - 1.5e-07 30.6 0.1 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS81086.1 - 3.2e-06 26.2 0.3 0.00047 19.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS81086.1 - 3e-05 23.9 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS81086.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS81086.1 - 0.002 16.6 0.1 0.042 12.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS81086.1 - 0.0041 17.0 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS81086.1 - 0.0054 16.8 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81086.1 - 0.059 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Sec1 PF00995.18 ETS81087.1 - 1.1e-147 493.0 0.0 1.4e-147 492.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 ETS81088.1 - 0.00018 21.1 1.7 0.00032 20.3 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS81088.1 - 0.022 14.7 3.0 0.039 13.9 2.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type 2_5_RNA_ligase2 PF13563.1 ETS81089.1 - 1.3e-13 50.9 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ank_2 PF12796.2 ETS81090.1 - 3.9e-44 148.8 5.2 1.6e-10 41.1 0.0 6.3 3 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81090.1 - 2.3e-36 121.8 0.2 1.8e-09 36.9 0.1 10.7 10 1 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 ETS81090.1 - 9.4e-34 115.1 5.4 1.4e-06 28.6 0.0 8.2 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81090.1 - 8.7e-30 102.0 8.6 9.8e-08 32.0 0.1 8.8 6 3 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS81090.1 - 1.5e-29 99.0 0.7 1.7e-06 27.7 0.1 10.3 11 0 0 11 11 11 4 Ankyrin repeat CorA PF01544.13 ETS81091.1 - 6.3e-08 31.9 2.7 1.6e-07 30.6 1.9 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_98C PF08307.6 ETS81091.1 - 0.0096 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain CPSase_L_chain PF00289.17 ETS81092.1 - 2.8e-31 107.8 0.1 4.1e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D2 PF02786.12 ETS81092.1 - 1.3e-08 34.3 0.1 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 ETS81092.1 - 0.00036 19.3 0.0 0.00041 19.1 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 ETS81092.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Aminotran_3 PF00202.16 ETS81093.1 - 5e-76 255.7 0.0 6.7e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Cecropin PF00272.14 ETS81093.1 - 0.084 12.4 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Cecropin family DUF659 PF04937.10 ETS81093.1 - 0.16 11.4 0.0 0.67 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Fungal_trans_2 PF11951.3 ETS81094.1 - 1.3e-46 158.9 0.6 1.5e-46 158.7 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81095.1 - 0.00066 19.5 6.8 0.0011 18.8 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_7 PF12973.2 ETS81096.1 - 1.5e-10 40.7 0.1 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.1 ETS81096.1 - 0.046 12.6 0.1 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_2 PF07883.6 ETS81096.1 - 0.047 13.2 1.2 0.084 12.3 0.8 1.5 1 0 0 1 1 1 0 Cupin domain Chitin_bind_4 PF00379.18 ETS81096.1 - 0.065 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Insect cuticle protein LamB_YcsF PF03746.11 ETS81097.1 - 2.4e-16 59.5 0.0 2.8e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AA_permease PF00324.16 ETS81098.1 - 1.5e-92 310.4 36.5 1.8e-92 310.1 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS81098.1 - 2.3e-21 75.8 37.7 2.9e-21 75.5 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease Saccharop_dh PF03435.13 ETS81099.1 - 9.9e-21 74.1 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETS81099.1 - 1.3e-07 31.8 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS81099.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4448 PF14610.1 ETS81100.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Sulfatase PF00884.18 ETS81101.1 - 9.3e-66 222.0 0.1 1.3e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS81101.1 - 5.9e-09 35.7 1.7 3.3e-08 33.2 1.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 ETS81101.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.12 ETS81101.1 - 0.033 12.6 0.1 0.059 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ACP PF06857.6 ETS81102.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Fungal_trans PF04082.13 ETS81103.1 - 2.8e-11 42.8 0.0 4.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81103.1 - 4.9e-10 39.1 6.3 8.5e-10 38.3 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS81104.1 - 1.3e-21 76.7 56.4 1.9e-20 72.8 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 ETS81105.1 - 4e-20 72.1 0.0 5.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS81105.1 - 1.3e-11 43.9 1.5 2.2e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS81105.1 - 6.3e-06 24.9 0.2 0.0061 15.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 ETS81105.1 - 9.5e-05 22.7 0.2 0.22 11.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS81105.1 - 0.00012 22.1 0.0 0.00036 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS81105.1 - 0.00032 20.6 0.0 0.0019 18.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS81105.1 - 0.00074 19.5 0.1 0.0027 17.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS81105.1 - 0.0029 16.5 0.3 0.046 12.5 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Yae1_N PF09811.4 ETS81105.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Thi4 PF01946.12 ETS81105.1 - 0.029 13.4 0.1 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family SE PF08491.5 ETS81105.1 - 0.046 12.5 0.0 0.15 10.8 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.7 ETS81105.1 - 0.088 11.7 0.5 8.3 5.2 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 2OG-FeII_Oxy PF03171.15 ETS81106.1 - 6.3e-13 48.8 0.1 9.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS81106.1 - 6.4e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Memo PF01875.12 ETS81106.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Memo-like protein Polyketide_cyc2 PF10604.4 ETS81108.1 - 1.6e-05 25.0 0.0 2.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 ETS81108.1 - 0.0035 17.3 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.17 ETS81109.1 - 1.4e-54 185.3 0.0 6.5e-54 183.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 ETS81110.1 - 1.7e-05 24.8 3.9 0.00045 20.3 0.2 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS81110.1 - 0.00011 22.2 5.1 0.006 16.8 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 ETS81110.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding GFA PF04828.9 ETS81110.1 - 0.031 14.1 0.9 0.18 11.7 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4451 PF14616.1 ETS81110.1 - 0.036 13.8 0.8 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-H2C2_2 PF13465.1 ETS81110.1 - 0.038 14.2 7.5 2.8 8.3 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS81110.1 - 0.043 13.7 1.8 0.38 10.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Cep57_CLD_2 PF14197.1 ETS81110.1 - 0.16 11.9 4.3 0.41 10.6 3.0 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 PRELI PF04707.9 ETS81111.1 - 4.9e-20 71.6 0.0 4.3e-18 65.3 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family RNase_H PF00075.19 ETS81112.1 - 1.4e-13 51.2 0.0 2.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF787 PF05619.6 ETS81112.1 - 0.17 10.5 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Peptidase_S10 PF00450.17 ETS81114.1 - 4.1e-89 299.6 0.1 5.4e-89 299.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RF-1 PF00472.15 ETS81115.1 - 2.8e-34 117.3 3.0 7.8e-34 115.8 2.1 1.8 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 ETS81115.1 - 1.7e-25 88.9 0.0 6.9e-25 87.0 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Baculo_PEP_C PF04513.7 ETS81115.1 - 1.2 9.0 3.9 3.4 7.5 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4066 PF13278.1 ETS81116.1 - 2.5e-13 49.6 0.1 2.1e-06 27.1 0.1 2.1 1 1 1 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS81116.1 - 0.016 14.6 0.0 0.88 9.0 0.0 2.1 1 1 1 2 2 2 0 DJ-1/PfpI family LcrR PF09621.5 ETS81116.1 - 0.14 11.3 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) adh_short PF00106.20 ETS81117.1 - 4e-15 56.1 3.7 4.6e-14 52.6 2.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81117.1 - 2.7e-08 33.9 0.7 4.2e-08 33.2 0.5 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 ETS81117.1 - 7.4e-08 31.9 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS81117.1 - 9.8e-06 25.6 0.1 1.7e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS81117.1 - 2.8e-05 23.4 0.0 3.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 ETS81117.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS81117.1 - 0.00038 20.8 0.0 0.00089 19.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.10 ETS81117.1 - 0.0034 17.0 0.6 0.0058 16.2 0.1 1.5 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 ETS81117.1 - 0.0081 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 ETS81117.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 ETS81117.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2568 PF10823.3 ETS81117.1 - 0.068 13.4 0.2 2.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Rossmann-like PF10727.4 ETS81117.1 - 0.072 12.8 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Rossmann-like domain GH-E PF14410.1 ETS81118.1 - 0.14 12.2 2.3 3.6 7.8 0.1 3.5 4 0 0 4 4 4 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Peptidase_M28 PF04389.12 ETS81119.1 - 1.9e-26 92.8 0.1 3.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 SUD-M PF11633.3 ETS81119.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain F-box-like PF12937.2 ETS81120.1 - 0.0005 19.7 0.4 0.0081 15.8 0.0 2.5 2 0 0 2 2 2 1 F-box-like HET PF06985.6 ETS81122.1 - 1e-30 106.7 1.4 1.5e-30 106.1 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CwfJ_C_1 PF04677.10 ETS81122.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.11 ETS81123.1 - 4.6e-17 61.7 12.9 4.6e-17 61.7 9.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81123.1 - 5.7e-11 41.6 0.7 5.7e-11 41.6 0.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter DUF872 PF05915.7 ETS81123.1 - 0.05 13.4 0.3 0.32 10.8 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.11 ETS81124.1 - 1.7e-35 122.3 4.6 1.7e-35 122.3 3.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81124.1 - 4.8e-07 28.7 0.5 4.8e-07 28.7 0.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.2 ETS81125.1 - 2.6e-25 88.5 3.4 8.3e-13 48.4 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81125.1 - 6.9e-18 63.4 3.6 5.5e-06 25.9 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 ETS81125.1 - 3.1e-14 53.0 1.8 0.00012 22.4 0.1 5.3 2 1 4 6 6 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81125.1 - 5.4e-12 45.5 2.1 1.5e-05 25.0 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 ETS81125.1 - 8.6e-10 38.5 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 ETS81125.1 - 2e-08 33.7 0.9 0.99 9.8 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat AAA_16 PF13191.1 ETS81125.1 - 7.1e-07 29.3 0.0 1.1e-05 25.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS81125.1 - 4.9e-06 26.7 0.0 3.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 ETS81125.1 - 3.9e-05 23.6 1.8 0.0042 16.9 1.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family NB-ARC PF00931.17 ETS81125.1 - 0.00069 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 ETS81125.1 - 0.0049 17.0 0.0 0.024 14.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETS81125.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 ETS81125.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 ETS81125.1 - 0.048 13.0 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain DUF676 PF05057.9 ETS81125.1 - 0.067 12.4 0.0 0.81 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 ETS81125.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein RNA_helicase PF00910.17 ETS81125.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2305 PF10230.4 ETS81125.1 - 0.22 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Zeta_toxin PF06414.7 ETS81125.1 - 0.26 10.3 0.0 0.49 9.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.9 ETS81125.1 - 0.83 8.5 2.6 5.4 5.9 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain CHAT PF12770.2 ETS81126.1 - 2.3e-30 105.7 0.0 4.3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 ETS81126.1 - 2.3e-11 43.4 10.3 0.0018 18.2 0.0 7.3 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETS81126.1 - 1.1e-10 40.9 1.1 0.033 13.8 0.0 6.1 3 2 5 8 8 8 3 TPR repeat TPR_10 PF13374.1 ETS81126.1 - 6.7e-07 29.0 11.6 0.059 13.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS81126.1 - 2.8e-05 23.6 2.6 2.6 8.1 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF4404 PF14357.1 ETS81126.1 - 0.0031 17.9 7.1 0.36 11.2 0.0 5.6 6 1 1 7 7 7 1 Domain of unknown function (DUF4404) Peptidase_C25 PF01364.13 ETS81126.1 - 0.042 12.8 0.0 0.093 11.6 0.0 1.5 2 0 0 2 2 2 0 Peptidase family C25 TPR_1 PF00515.23 ETS81126.1 - 2.3 7.9 5.2 5.7 6.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 ETS81127.1 - 7.5e-18 65.1 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain RMMBL PF07521.7 ETS81127.1 - 0.11 12.3 0.3 1.7 8.5 0.1 2.8 3 0 0 3 3 3 0 RNA-metabolising metallo-beta-lactamase DUF3425 PF11905.3 ETS81128.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) Lactamase_B_2 PF12706.2 ETS81129.1 - 1.6e-36 125.7 0.1 2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS81129.1 - 9.9e-10 38.3 0.0 2.9e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS81129.1 - 0.00021 21.0 0.1 0.003 17.2 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily adh_short PF00106.20 ETS81130.1 - 4.5e-14 52.7 0.5 6.8e-14 52.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81130.1 - 1.2e-06 28.2 0.1 1.9e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81130.1 - 4.8e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS81130.1 - 0.00071 19.6 0.2 0.0021 18.0 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 ETS81130.1 - 0.0029 17.3 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Otopetrin PF03189.8 ETS81131.1 - 0.025 13.5 0.6 0.025 13.5 0.4 1.8 1 1 1 2 2 2 0 Otopetrin Tyrosinase PF00264.15 ETS81132.1 - 9.5e-33 114.2 0.0 1.6e-32 113.4 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase SIR2 PF02146.12 ETS81133.1 - 9.5e-34 116.6 0.0 8.8e-22 77.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 ETS81133.1 - 0.0085 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MARVEL PF01284.18 ETS81134.1 - 0.0025 17.6 6.3 0.0062 16.3 4.5 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 ETS81134.1 - 0.018 15.1 2.0 1.2 9.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) YwiC PF14256.1 ETS81134.1 - 0.029 14.4 2.3 0.5 10.4 1.2 2.1 2 0 0 2 2 2 0 YwiC-like protein DUF4231 PF14015.1 ETS81134.1 - 0.084 12.8 2.4 0.85 9.6 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF588 PF04535.7 ETS81134.1 - 0.12 11.9 4.3 2.3 7.7 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF588) Shisa PF13908.1 ETS81134.1 - 0.13 12.4 0.1 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AA_permease_2 PF13520.1 ETS81134.1 - 0.19 10.2 2.2 0.45 8.9 1.5 1.6 1 1 0 1 1 1 0 Amino acid permease DUF998 PF06197.8 ETS81134.1 - 7.9 5.7 14.1 4.7 6.4 7.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Flavoprotein PF02441.14 ETS81135.1 - 1.4e-36 124.9 0.1 5.7e-36 123.0 0.1 1.8 1 1 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 ETS81136.1 - 5.6e-15 55.0 0.0 9.2e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin G_glu_transpept PF01019.16 ETS81137.1 - 1.5e-146 488.9 0.0 1.7e-146 488.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1996 PF09362.5 ETS81138.1 - 2.1e-90 302.4 1.5 2.9e-90 302.0 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sugar_tr PF00083.19 ETS81139.1 - 6.4e-112 374.4 27.7 7.6e-112 374.1 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81139.1 - 1.3e-21 76.7 50.2 1.9e-14 53.1 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS81139.1 - 4.1e-10 38.4 11.2 4.5e-06 25.1 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3366 PF11846.3 ETS81140.1 - 1.6 8.5 4.8 0.96 9.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) 4HBT_2 PF13279.1 ETS81141.1 - 3.2e-07 30.8 0.0 5.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.6 ETS81142.1 - 1.9e-12 46.8 13.8 3.2e-12 46.1 9.5 1.4 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.6 ETS81142.1 - 0.72 7.6 6.2 0.7 7.6 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hexapep PF00132.19 ETS81143.1 - 5.1e-09 35.2 6.8 0.0002 20.7 1.3 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS81143.1 - 0.0007 19.1 2.2 0.0045 16.5 1.1 2.9 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Oxidored_FMN PF00724.15 ETS81144.1 - 1.2e-90 303.9 0.0 1.4e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CsbD PF05532.7 ETS81146.1 - 4.4e-05 23.0 0.9 0.00011 21.8 0.3 1.9 1 1 1 2 2 2 1 CsbD-like LMWPc PF01451.16 ETS81147.1 - 2.1e-37 128.5 0.0 2.3e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase adh_short PF00106.20 ETS81148.1 - 1.8e-22 80.0 0.1 2.6e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81148.1 - 7e-10 39.0 0.0 9.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS81148.1 - 9.3e-10 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81148.1 - 4.6e-05 22.9 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS81148.1 - 0.0054 16.4 0.4 0.019 14.7 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Clr5 PF14420.1 ETS81149.1 - 1.1e-14 53.9 0.1 1e-13 50.9 0.1 2.4 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 ETS81149.1 - 0.0084 16.0 2.9 0.012 15.4 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS81149.1 - 0.017 15.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 ETS81149.1 - 0.022 15.3 1.6 0.05 14.2 0.1 2.3 2 0 0 2 2 2 0 Sel1 repeat DUF4187 PF13821.1 ETS81149.1 - 0.4 10.3 2.0 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) DUF1325 PF07039.6 ETS81150.1 - 3.9e-26 91.1 0.0 6.1e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain ALIX_LYPXL_bnd PF13949.1 ETS81150.1 - 0.024 13.5 3.5 0.035 13.0 2.4 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4404 PF14357.1 ETS81150.1 - 0.11 12.9 3.3 0.22 11.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PMI_typeI PF01238.16 ETS81151.1 - 3.4e-141 470.5 0.0 3.9e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I 5_nucleotid_C PF02872.13 ETS81153.1 - 5e-35 120.7 0.0 8.1e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 ETS81153.1 - 1.6e-08 34.1 0.1 2.8e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IFT43 PF15305.1 ETS81153.1 - 0.049 13.6 0.7 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Fn3_assoc PF13287.1 ETS81153.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Fn3 associated Meth_synt_2 PF01717.13 ETS81154.1 - 3e-12 46.1 0.0 5.3e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 ETS81154.1 - 0.018 14.3 0.0 0.063 12.5 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 ETS81155.1 - 2.5e-08 33.5 0.0 8.7e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 ETS81155.1 - 0.004 16.7 0.6 0.035 13.7 0.4 2.3 1 1 0 1 1 1 1 F-box domain Ank PF00023.25 ETS81156.1 - 1.1e-19 69.1 0.6 4.4e-08 32.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 ETS81156.1 - 1.7e-17 63.5 0.3 3.7e-07 30.3 0.0 3.6 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS81156.1 - 2e-15 56.8 0.5 2.2e-06 28.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81156.1 - 4.6e-14 52.1 1.0 3.3e-06 27.1 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS81156.1 - 1.4e-10 40.3 0.2 0.0071 16.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 ETS81156.1 - 1.2e-06 28.1 0.3 9.4e-06 25.2 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain DUF3782 PF12644.2 ETS81156.1 - 0.084 12.6 0.3 0.45 10.3 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) KxDL PF10241.4 ETS81156.1 - 7.3 6.5 8.0 10 6.0 0.8 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein Ank_2 PF12796.2 ETS81157.1 - 6.5e-60 199.4 1.4 4.1e-19 68.7 0.0 5.9 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81157.1 - 1.2e-54 179.5 4.6 1.2e-08 34.2 0.1 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 ETS81157.1 - 3.4e-45 151.6 0.8 2.4e-08 34.2 0.0 8.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS81157.1 - 7.8e-36 118.5 0.7 3.2e-08 33.0 0.0 9.6 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 ETS81157.1 - 1.1e-35 120.7 4.1 2e-07 31.0 0.3 7.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Aldo_ket_red PF00248.16 ETS81158.1 - 1.5e-53 181.4 0.0 1.8e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EmrE PF13536.1 ETS81159.1 - 6.3e-11 42.4 19.5 3.9e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 ETS81159.1 - 9.6e-11 41.8 30.6 4.8e-07 29.8 1.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 ETS81159.1 - 0.0055 15.8 0.0 0.0055 15.8 0.0 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 ETS81159.1 - 0.052 13.2 22.1 0.19 11.3 8.9 3.1 3 0 0 3 3 3 0 Triose-phosphate Transporter family MFS_1 PF07690.11 ETS81161.1 - 7e-32 110.5 22.7 7e-32 110.5 15.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81161.1 - 2.1e-12 46.3 7.2 2.1e-12 46.3 5.0 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Med15 PF09606.5 ETS81163.1 - 0.13 10.4 54.0 0.18 9.9 37.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Polyketide_cyc2 PF10604.4 ETS81166.1 - 0.047 13.8 0.3 0.065 13.4 0.2 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport SGL PF08450.7 ETS81167.1 - 0.00052 19.4 0.7 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 ETS81167.1 - 0.013 15.4 0.4 0.17 11.8 0.1 2.7 2 0 0 2 2 2 0 NHL repeat Oxidored_FMN PF00724.15 ETS81168.1 - 9.5e-50 169.5 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.7 ETS81168.1 - 0.00089 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Dus PF01207.12 ETS81168.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) GTP_cyclohydro2 PF00925.15 ETS81169.1 - 3.8e-57 192.2 0.0 6.9e-55 184.8 0.0 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase II NDUF_B7 PF05676.8 ETS81171.1 - 1.5e-31 107.6 2.0 1.8e-31 107.3 1.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 ETS81171.1 - 0.012 15.3 2.0 0.014 15.1 1.2 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 ETS81171.1 - 1.5 9.1 5.4 1.8 8.8 1.3 2.2 1 1 1 2 2 2 0 Antifungal protein Peptidase_S28 PF05577.7 ETS81172.1 - 9.5e-57 192.4 2.0 2.5e-56 191.0 1.4 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.3 ETS81172.1 - 0.032 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) HET PF06985.6 ETS81173.1 - 4.3e-27 94.9 0.0 8.8e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VWA_2 PF13519.1 ETS81174.1 - 1.2e-05 25.4 0.0 0.0059 16.7 0.0 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain zinc_ribbon_5 PF13719.1 ETS81174.1 - 7e-05 22.3 0.8 0.00015 21.2 0.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS81174.1 - 0.00032 20.3 1.3 0.00072 19.1 0.9 1.6 1 0 0 1 1 1 1 zinc-ribbon domain VWA PF00092.23 ETS81174.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETS81174.1 - 0.024 13.7 0.2 0.26 10.4 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Zn_Tnp_IS1595 PF12760.2 ETS81174.1 - 0.088 12.6 3.0 0.25 11.1 2.1 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF737 PF05300.6 ETS81175.1 - 0.12 12.3 3.3 0.21 11.5 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Ifi-6-16 PF06140.8 ETS81176.1 - 0.00018 21.2 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.8 ETS81176.1 - 0.0028 17.9 0.2 0.0055 17.0 0.1 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) NTP_transf_3 PF12804.2 ETS81176.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain MFS_1 PF07690.11 ETS81177.1 - 2.1e-29 102.3 14.8 2.1e-29 102.3 10.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS81177.1 - 0.00015 20.1 1.0 0.00015 20.1 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cutinase PF01083.17 ETS81178.1 - 4.3e-45 153.6 6.2 5.2e-45 153.3 4.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS81178.1 - 6.4e-06 25.7 0.6 9.1e-06 25.2 0.4 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 ETS81178.1 - 2.7e-05 23.9 0.2 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS81178.1 - 0.0021 17.9 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS81178.1 - 0.089 12.3 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.13 ETS81179.1 - 2.3e-08 33.7 6.2 3.5e-08 33.2 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 ETS81179.1 - 0.25 11.0 2.4 0.54 10.0 1.7 1.5 1 1 0 1 1 1 0 PHD-finger DDE_3 PF13358.1 ETS81180.1 - 1.2e-20 73.7 0.1 3.7e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 ETS81180.1 - 8.2e-10 38.6 0.4 1.8e-09 37.4 0.3 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 ETS81180.1 - 0.00012 22.2 0.0 0.00012 22.2 0.0 3.1 2 1 1 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.1 ETS81180.1 - 0.0097 16.6 15.3 0.64 10.8 3.0 4.1 3 2 2 5 5 5 2 Homeodomain-like domain HTH_38 PF13936.1 ETS81180.1 - 0.029 13.9 2.0 0.035 13.6 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Aa_trans PF01490.13 ETS81181.1 - 5.8e-56 189.7 37.1 6.6e-56 189.5 25.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3455 PF11937.3 ETS81182.1 - 5.2e-28 98.1 0.0 9.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pkinase PF00069.20 ETS81183.1 - 3.5e-72 242.6 0.0 4.1e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81183.1 - 2.6e-31 108.6 0.0 3.6e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS81183.1 - 0.02 14.6 0.1 0.069 12.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 ETS81183.1 - 0.088 11.8 0.1 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FliT PF05400.8 ETS81184.1 - 0.08 13.3 1.3 0.18 12.2 0.9 1.7 1 1 0 1 1 1 0 Flagellar protein FliT Pro_isomerase PF00160.16 ETS81185.1 - 3.6e-35 121.4 0.0 6e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 ETS81185.1 - 7.9e-16 57.4 0.0 1.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS81185.1 - 4.8e-11 42.4 0.0 9.8e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS81185.1 - 1.8e-09 37.2 0.0 4.9e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 ETS81186.1 - 5.2e-19 68.3 0.0 1.2e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS81186.1 - 9.2e-05 22.9 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS81186.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 ETS81186.1 - 0.0028 17.3 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 ETS81186.1 - 0.0047 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 ETS81186.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 ETS81186.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 ETS81186.1 - 0.027 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 ETS81186.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 ETS81186.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 ETS81186.1 - 0.13 12.2 0.0 0.68 9.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81186.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_2 PF00890.19 ETS81187.1 - 5.4e-85 285.7 1.2 6.7e-85 285.4 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 ETS81187.1 - 2.4e-21 75.3 0.1 8.2e-20 70.3 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 ETS81187.1 - 2e-13 49.9 2.5 1e-12 47.6 1.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 ETS81187.1 - 1.2e-10 41.0 0.3 4.3e-10 39.2 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS81187.1 - 6e-09 35.7 2.2 1.1e-07 31.7 0.3 3.3 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS81187.1 - 2.1e-08 34.2 0.0 1.4e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS81187.1 - 1.6e-06 26.8 0.9 0.0049 15.4 0.1 3.4 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 ETS81187.1 - 2.7e-05 23.3 0.7 0.0061 15.6 0.1 2.7 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.14 ETS81187.1 - 0.0001 21.5 1.8 0.0061 15.6 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 ETS81187.1 - 0.00035 19.5 1.9 0.084 11.7 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 ETS81187.1 - 0.00055 19.1 0.4 0.21 10.6 0.0 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 ETS81187.1 - 0.03 14.3 1.1 0.094 12.7 0.8 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS81187.1 - 0.49 10.8 4.8 4 7.9 1.3 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS81188.1 - 8e-60 203.1 1.5 1e-58 199.5 1.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS81188.1 - 1.1e-08 34.9 1.4 2.7e-08 33.7 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS81188.1 - 0.00043 20.4 0.1 0.0039 17.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS81188.1 - 0.0096 14.8 0.0 0.78 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS81188.1 - 0.011 14.8 0.2 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 ETS81188.1 - 0.019 15.0 0.1 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS81188.1 - 0.024 15.0 3.3 0.32 11.4 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS81188.1 - 0.042 12.6 0.3 0.071 11.9 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 ETS81188.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81188.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS81188.1 - 0.19 10.1 0.3 0.29 9.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Fasciclin PF02469.17 ETS81189.1 - 0.0098 15.9 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Bap31 PF05529.7 ETS81190.1 - 1.5e-64 216.9 5.0 1.9e-64 216.6 3.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2956 PF11169.3 ETS81190.1 - 0.073 13.0 4.3 0.14 12.1 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DivIC PF04977.10 ETS81190.1 - 0.15 11.5 10.3 0.14 11.6 1.3 3.3 2 2 2 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.3 ETS81190.1 - 0.19 11.5 5.6 0.21 11.4 2.7 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 ETS81190.1 - 0.27 10.1 2.8 0.41 9.5 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.7 ETS81190.1 - 0.29 10.9 2.8 0.28 10.9 0.7 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HHH PF00633.18 ETS81191.1 - 0.0011 18.5 0.1 0.0032 17.0 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tricorn_C1 PF14684.1 ETS81191.1 - 0.099 12.5 0.0 3 7.7 0.0 2.5 3 0 0 3 3 3 0 Tricorn protease C1 domain zf-met2 PF12907.2 ETS81192.1 - 2.9e-16 59.1 2.9 3.9e-16 58.7 2.0 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 ETS81192.1 - 1.2e-07 32.3 9.2 1.2e-07 32.3 6.4 1.7 2 0 0 2 2 2 1 4F5 protein family HypA PF01155.14 ETS81192.1 - 0.023 14.3 0.6 0.029 14.0 0.4 1.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_4 PF13894.1 ETS81192.1 - 0.029 14.7 0.5 0.057 13.7 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Neurexophilin PF06312.7 ETS81192.1 - 0.13 11.5 2.1 0.14 11.3 1.5 1.0 1 0 0 1 1 1 0 Neurexophilin DIOX_N PF14226.1 ETS81193.1 - 1.2e-28 99.9 0.0 2.9e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS81193.1 - 1.3e-13 51.0 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 ETS81194.1 - 6.5e-10 38.5 2.8 0.00071 19.3 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 ETS81195.1 - 3.5e-30 103.8 0.8 4.2e-30 103.5 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 ETS81195.1 - 0.099 12.7 0.3 0.17 12.0 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mqo PF06039.10 ETS81195.1 - 0.14 10.3 0.0 0.15 10.2 0.0 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) IFP_35_N PF07334.8 ETS81196.1 - 0.34 10.9 4.0 3.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fer4_13 PF13370.1 ETS81196.1 - 1 9.7 5.8 6.1 7.3 0.5 3.7 3 2 0 3 3 3 0 4Fe-4S single cluster domain HAD_2 PF13419.1 ETS81198.1 - 1.5e-24 87.1 0.0 2.1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS81198.1 - 8.8e-06 26.2 0.0 1.4e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ERGIC_N PF13850.1 ETS81198.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RRN9 PF10680.4 ETS81199.1 - 1e-16 60.3 0.4 3.2e-16 58.8 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.21 ETS81199.1 - 0.79 10.1 3.3 0.45 10.9 0.7 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type SOG2 PF10428.4 ETS81199.1 - 7.6 5.0 10.5 58 2.1 0.5 2.4 1 1 1 2 2 2 0 RAM signalling pathway protein Pescadillo_N PF06732.6 ETS81200.1 - 4.6e-112 373.8 0.3 1.6e-111 372.0 0.2 1.9 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 ETS81200.1 - 7.4e-11 42.0 0.0 1e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain SGT1 PF07093.6 ETS81200.1 - 0.012 13.9 16.7 0.019 13.3 11.6 1.2 1 0 0 1 1 1 0 SGT1 protein PIG-U PF06728.8 ETS81201.1 - 1.5e-120 402.6 31.1 1.7e-120 402.4 21.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 ETS81201.1 - 0.00026 20.7 5.6 0.00042 20.0 3.8 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) tRNA-synt_1 PF00133.17 ETS81202.1 - 1.6e-162 541.6 0.0 2.4e-162 541.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 ETS81202.1 - 1.1e-22 80.2 0.0 8.6e-12 44.4 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 ETS81202.1 - 9.7e-16 57.8 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 ETS81202.1 - 2.4e-05 23.8 1.7 4.5e-05 22.9 1.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 ETS81202.1 - 4.8e-05 22.7 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 ETS81202.1 - 0.017 14.2 0.0 0.92 8.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NTR2 PF15458.1 ETS81203.1 - 6 6.0 7.9 1.1 8.4 1.5 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Tom37_C PF11801.3 ETS81204.1 - 8.8e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 ETS81204.1 - 3.7e-21 75.1 0.1 7.3e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 ETS81204.1 - 0.00028 20.7 0.1 0.00098 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS81204.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS81204.1 - 0.018 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS81204.1 - 0.033 14.1 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 ETS81205.1 - 2e-76 257.3 26.0 2.4e-76 257.1 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81205.1 - 5.7e-32 110.7 53.9 1.1e-29 103.2 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 ETS81205.1 - 0.068 13.2 0.9 0.21 11.7 0.6 1.8 1 0 0 1 1 1 0 Phage holin family 2 Exo_endo_phos PF03372.18 ETS81206.1 - 3e-14 53.5 0.1 3.4e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETS81206.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase SPRY PF00622.23 ETS81208.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.19 ETS81209.1 - 2.9e-39 133.8 31.8 1.3e-20 73.4 8.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MFS_1 PF07690.11 ETS81210.1 - 1.9e-24 86.0 56.4 1.7e-20 73.0 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cep57_MT_bd PF06657.8 ETS81211.1 - 1.1e-18 66.9 0.1 1.1e-18 66.9 0.1 4.4 4 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.13 ETS81211.1 - 0.00044 19.9 24.3 0.073 12.7 1.3 5.8 4 1 2 6 6 6 3 Homeobox associated leucine zipper DUF904 PF06005.7 ETS81211.1 - 0.00047 20.4 40.0 0.054 13.7 2.9 6.6 3 1 3 6 6 6 3 Protein of unknown function (DUF904) DUF972 PF06156.8 ETS81211.1 - 1.7 9.0 34.2 1.4 9.3 2.7 6.2 2 1 4 6 6 6 0 Protein of unknown function (DUF972) DivIC PF04977.10 ETS81211.1 - 2 7.9 28.6 1.4 8.4 0.3 5.5 2 1 3 5 5 5 0 Septum formation initiator BLOC1_2 PF10046.4 ETS81211.1 - 7.1 6.8 26.2 1.1 9.4 1.5 4.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 ETS81211.1 - 9 5.8 50.6 0.44 10.1 12.1 3.9 2 1 1 3 3 3 0 IncA protein DUF1772 PF08592.6 ETS81214.1 - 7.7e-22 77.5 5.3 1.1e-21 77.0 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) HbrB PF08539.6 ETS81214.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 HbrB-like Acetyltransf_3 PF13302.1 ETS81215.1 - 5.9e-37 126.9 0.0 7.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS81215.1 - 4.2e-05 23.5 0.0 0.0075 16.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS81215.1 - 0.018 15.0 0.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 ETS81216.1 - 7.9e-20 70.8 0.3 1.3e-19 70.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81216.1 - 4.5e-07 29.6 12.6 7.8e-07 28.9 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L18ae PF01775.12 ETS81217.1 - 6.5e-48 161.7 0.8 8.6e-48 161.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 ETS81218.1 - 2.4e-14 53.5 0.0 1.9e-13 50.6 0.0 2.3 1 1 1 2 2 2 1 PCI domain TPR_11 PF13414.1 ETS81218.1 - 0.011 15.3 0.2 0.22 11.2 0.0 3.0 2 2 0 2 2 2 0 TPR repeat Peptidase_M76 PF09768.4 ETS81218.1 - 0.08 12.4 0.1 5.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Peptidase M76 family BTB PF00651.26 ETS81219.1 - 3.1e-07 30.3 0.1 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 ETS81219.1 - 0.038 14.0 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain BTB_2 PF02214.17 ETS81219.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF3070 PF11270.3 ETS81220.1 - 1.5 8.6 6.8 11 5.8 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3070) NUMOD4 PF07463.6 ETS81221.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NUMOD4 motif WD40 PF00400.27 ETS81222.1 - 3.6e-30 102.7 10.3 4.7e-08 32.6 0.0 6.9 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS81222.1 - 1.4e-05 24.9 0.0 0.062 13.0 0.0 3.6 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 ETS81222.1 - 0.00022 20.6 0.1 0.00075 18.9 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif PSII_BNR PF14870.1 ETS81222.1 - 0.14 11.1 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 ABC_tran PF00005.22 ETS81223.1 - 5.4e-50 169.2 0.0 1.8e-28 99.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 ETS81223.1 - 8.8e-34 117.1 21.7 6.6e-20 71.6 6.6 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS81223.1 - 1.8e-09 37.1 0.1 0.00078 18.7 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 ETS81223.1 - 3.4e-05 23.3 0.0 0.025 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS81223.1 - 3.4e-05 23.2 0.8 0.13 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS81223.1 - 7e-05 23.2 0.4 0.0044 17.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 ETS81223.1 - 0.00052 18.9 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 ETS81223.1 - 0.00066 18.8 0.4 0.34 10.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETS81223.1 - 0.0011 18.9 0.1 0.92 9.4 0.0 3.5 2 2 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS81223.1 - 0.0014 18.6 0.4 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 ETS81223.1 - 0.0081 16.1 0.3 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS81223.1 - 0.016 15.3 0.0 36 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 ETS81223.1 - 0.029 14.1 1.9 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 ETS81223.1 - 0.063 12.8 0.3 6.1 6.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 ETS81223.1 - 0.065 12.3 0.0 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 ETS81223.1 - 0.07 13.6 2.7 6.1 7.3 0.0 3.3 4 0 0 4 4 2 0 Miro-like protein SbcCD_C PF13558.1 ETS81223.1 - 0.1 12.5 0.0 14 5.6 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 ETS81223.1 - 0.15 10.8 0.4 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 ETS81223.1 - 0.17 11.3 0.0 17 4.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS81223.1 - 0.48 9.8 2.5 7.3 5.9 0.1 2.6 2 1 0 2 2 2 0 AAA-like domain Asp PF00026.18 ETS81224.1 - 1e-76 258.2 2.4 1.2e-76 257.9 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS81224.1 - 2.1e-07 31.0 0.5 9.6e-07 28.8 0.3 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS81224.1 - 1e-06 29.1 2.4 0.00015 22.2 0.3 3.5 3 1 0 3 3 3 1 Aspartyl protease WLM PF08325.5 ETS81225.1 - 1.6e-56 191.1 0.1 2.5e-56 190.4 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 ETS81225.1 - 0.0031 16.5 4.6 0.0031 16.5 3.2 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 ETS81225.1 - 0.57 9.9 3.9 1.4 8.7 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 DZR PF12773.2 ETS81225.1 - 0.87 9.4 8.8 8.5 6.2 6.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 ETS81225.1 - 2.4 7.7 16.9 0.12 11.9 0.3 3.5 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger HATPase_c PF02518.21 ETS81226.1 - 1.8e-29 101.6 0.1 3.7e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS81226.1 - 3.8e-22 78.0 0.1 1.5e-21 76.1 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 ETS81226.1 - 7.7e-22 77.4 0.2 1.9e-21 76.1 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 ETS81226.1 - 3.7e-17 62.2 0.1 9.3e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 ETS81226.1 - 6.9e-14 52.0 0.0 1.3e-08 35.1 0.0 4.4 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.5 ETS81226.1 - 1.5e-07 31.4 0.2 0.00016 21.6 0.0 4.0 4 0 0 4 4 4 1 PAS fold PAS PF00989.19 ETS81226.1 - 7.9e-07 28.8 0.0 0.047 13.4 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 ETS81226.1 - 4e-06 26.4 0.0 0.0053 16.5 0.0 3.6 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.1 ETS81226.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_circ_N PF07157.7 ETS81227.1 - 0.18 11.9 1.0 0.35 11.0 0.1 1.9 2 0 0 2 2 2 0 DNA circularisation protein N-terminus DUF2404 PF10296.4 ETS81228.1 - 0.00036 20.5 0.0 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Nucleoplasmin PF03066.10 ETS81228.1 - 0.87 9.0 15.9 0.3 10.5 1.8 3.1 3 0 0 3 3 3 0 Nucleoplasmin PIP5K PF01504.13 ETS81229.1 - 8e-57 192.2 0.1 1.5e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 ETS81229.1 - 6.6e-21 74.4 0.0 1.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 ETS81229.1 - 8e-12 44.8 10.7 2e-11 43.6 7.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger IF4E PF01652.13 ETS81231.1 - 6.8e-59 198.0 0.2 8.4e-59 197.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 ETS81232.1 - 2e-70 237.3 0.0 2.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS81232.1 - 1e-13 52.0 0.1 3.2e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 ETS81233.1 - 4.9e-28 96.8 0.8 7.6e-28 96.2 0.5 1.3 1 0 0 1 1 1 1 BolA-like protein Glyco_hydro_3 PF00933.16 ETS81233.1 - 0.058 12.3 0.1 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain RPA_C PF08784.6 ETS81233.1 - 0.094 13.1 1.7 1.2 9.5 1.2 2.2 1 1 0 1 1 1 0 Replication protein A C terminal DUF726 PF05277.7 ETS81234.1 - 2.1e-114 382.0 0.1 2.8e-114 381.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 ETS81234.1 - 0.00012 22.0 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS81234.1 - 0.002 18.3 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 ETS81234.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 ETS81234.1 - 0.013 14.4 0.1 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase PE-PPE PF08237.6 ETS81234.1 - 0.026 13.9 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 PE-PPE domain Lipase_3 PF01764.20 ETS81234.1 - 0.055 13.0 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Cutinase PF01083.17 ETS81234.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 ETS81234.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_hydro_67M PF07488.7 ETS81236.1 - 1.2e-140 468.0 0.0 1.5e-140 467.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67N PF03648.9 ETS81236.1 - 1.5e-25 89.6 0.0 2.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_67C PF07477.7 ETS81236.1 - 8.7e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_20b PF02838.10 ETS81236.1 - 0.094 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67C PF07477.7 ETS81237.1 - 2.4e-54 184.1 0.1 3.2e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus DUF3419 PF11899.3 ETS81238.1 - 1.2e-153 511.3 0.1 1.8e-153 510.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 ETS81238.1 - 1.6e-13 50.6 0.1 7.3e-09 35.6 0.0 3.6 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 ETS81238.1 - 3.7e-13 49.5 0.0 4.7e-12 45.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81238.1 - 5.7e-10 39.5 0.0 6.9e-09 36.0 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81238.1 - 1.5e-09 38.4 0.0 2e-08 34.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81238.1 - 2.7e-08 33.5 0.0 6.4e-05 22.5 0.0 3.5 4 0 0 4 4 4 2 Methyltransferase domain Ubie_methyltran PF01209.13 ETS81238.1 - 1.9e-07 30.4 0.0 0.00023 20.3 0.0 2.7 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 ETS81238.1 - 1.7e-05 25.2 0.0 0.0067 16.8 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81238.1 - 2.1e-05 24.8 0.0 7.9e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS81238.1 - 0.002 17.7 0.0 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 ETS81238.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ada3 PF10198.4 ETS81239.1 - 4e-46 156.0 0.6 8.7e-46 154.9 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.15 ETS81240.1 - 4.1e-61 207.4 1.2 6.7e-61 206.7 0.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 ETS81240.1 - 3.6e-55 185.3 5.9 2.4e-54 182.6 2.3 2.4 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 ETS81240.1 - 3.3e-42 142.3 0.1 8e-42 141.1 0.1 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 ETS81240.1 - 1.8e-38 130.5 0.1 4.8e-38 129.1 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 ETS81240.1 - 5.3e-06 26.1 3.3 1.5e-05 24.6 2.3 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 ETS81240.1 - 0.00025 20.7 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS81240.1 - 0.00032 20.0 0.6 0.0014 17.8 0.0 2.1 1 1 0 2 2 2 1 Amidohydrolase family HMG_box PF00505.14 ETS81241.1 - 6.3e-07 29.5 0.1 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS81241.1 - 0.00016 22.0 0.0 0.00057 20.1 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain DUF3305 PF11749.3 ETS81241.1 - 0.057 13.2 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) SOG2 PF10428.4 ETS81241.1 - 0.14 10.8 2.6 0.06 11.9 0.5 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Het-C PF07217.6 ETS81242.1 - 9.8e-259 859.6 0.1 1.6e-258 858.8 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Glyco_hydro_45 PF02015.11 ETS81243.1 - 8.7e-90 300.1 23.2 1e-89 299.9 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 MbtH PF03621.8 ETS81243.1 - 0.42 10.0 4.2 3 7.2 0.1 2.4 2 0 0 2 2 2 0 MbtH-like protein zf-RING_2 PF13639.1 ETS81244.1 - 4.8e-12 45.5 5.5 8.5e-12 44.7 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS81244.1 - 1.8e-06 27.4 5.2 3.3e-06 26.6 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS81244.1 - 3.3e-06 27.0 6.6 6.4e-06 26.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS81244.1 - 1.1e-05 25.0 4.2 2e-05 24.2 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS81244.1 - 4.4e-05 23.5 0.9 0.00011 22.2 0.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 ETS81244.1 - 0.00013 21.5 3.1 0.00025 20.6 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS81244.1 - 0.0013 18.5 7.2 0.003 17.4 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 ETS81244.1 - 0.0044 16.8 1.0 0.014 15.2 0.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger GP41 PF00517.12 ETS81244.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral envelope protein zf-RING_UBOX PF13445.1 ETS81244.1 - 0.023 14.4 4.8 0.062 13.0 0.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger YdjO PF14169.1 ETS81244.1 - 0.16 11.4 0.6 9.1 5.8 0.0 3.0 3 0 0 3 3 3 0 Cold-inducible protein YdjO RINGv PF12906.2 ETS81244.1 - 0.21 11.6 2.5 0.39 10.8 1.7 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 ETS81244.1 - 0.62 10.0 3.3 2.6 8.0 2.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_47 PF01532.15 ETS81245.1 - 1e-164 548.5 0.1 1.2e-164 548.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Clr5 PF14420.1 ETS81247.1 - 1.3e-19 69.8 2.8 1.3e-19 69.8 2.0 1.8 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 ETS81247.1 - 0.0031 17.4 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS81247.1 - 0.26 11.1 1.1 41 4.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3317 PF11779.3 ETS81248.1 - 1.8e-19 68.9 2.0 2.3e-19 68.5 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) p450 PF00067.17 ETS81249.1 - 5.4e-65 219.7 0.0 6.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phospholip_A2_3 PF09056.6 ETS81250.1 - 5.1e-42 142.5 0.2 6.7e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Maf PF02545.9 ETS81251.1 - 8.2e-45 152.3 0.0 1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 ETS81252.1 - 1.8e-08 33.9 0.0 3.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Methyltransf_17 PF12692.2 ETS81252.1 - 0.024 14.3 0.3 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase GvpG PF05120.7 ETS81252.1 - 0.13 12.0 2.6 0.23 11.2 1.8 1.4 1 0 0 1 1 1 0 Gas vesicle protein G tRNA-synt_2b PF00587.20 ETS81253.1 - 6.7e-49 165.7 0.0 9.5e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS81253.1 - 1.3e-09 37.8 0.1 2.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TRP PF06011.7 ETS81255.1 - 3.5e-145 483.9 25.6 4.2e-145 483.6 17.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 ETS81255.1 - 7.4e-41 139.4 5.5 1.1e-40 138.8 3.8 1.3 1 0 0 1 1 1 1 ML-like domain COesterase PF00135.23 ETS81256.1 - 2.5e-79 267.4 3.5 7.4e-79 265.8 2.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS81256.1 - 1.4e-05 24.7 0.2 5.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS81256.1 - 0.0065 15.7 0.6 0.019 14.2 0.4 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS81256.1 - 0.025 14.3 0.1 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Utp11 PF03998.8 ETS81257.1 - 4.9e-53 180.4 14.8 5.6e-53 180.2 10.3 1.0 1 0 0 1 1 1 1 Utp11 protein Spt5_N PF11942.3 ETS81257.1 - 0.022 15.3 3.6 0.022 15.3 2.5 3.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.1 ETS81257.1 - 3.5 7.8 12.1 11 6.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DAO PF01266.19 ETS81259.1 - 6.7e-20 71.2 0.0 9.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS81259.1 - 3.2e-06 26.2 0.1 4.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS81259.1 - 9.9e-05 22.2 0.1 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS81259.1 - 0.00013 22.3 0.1 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS81259.1 - 0.00029 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 ETS81259.1 - 0.0015 18.4 0.4 0.0044 16.9 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 ETS81259.1 - 0.0067 15.8 0.2 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 ETS81259.1 - 0.01 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS81259.1 - 0.011 14.8 1.3 0.013 14.5 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 ETS81259.1 - 0.022 13.6 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.12 ETS81259.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ETS81259.1 - 0.028 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETS81259.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 ETS81259.1 - 0.03 14.2 0.1 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 ETS81259.1 - 0.041 12.3 0.9 0.058 11.8 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_transf_4 PF13439.1 ETS81259.1 - 0.048 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.10 ETS81259.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 ETS81259.1 - 0.065 12.9 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 ETS81259.1 - 0.097 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETS81259.1 - 0.18 10.8 0.2 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 ETS81259.1 - 0.18 11.9 0.0 0.81 9.7 0.0 2.0 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NACHT PF05729.7 ETS81262.1 - 8.9e-11 41.7 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.21 ETS81262.1 - 9.7e-09 35.0 21.0 0.00061 19.9 3.3 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS81262.1 - 6.3e-06 26.2 14.6 0.0015 18.7 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain AAA_16 PF13191.1 ETS81262.1 - 7.7e-06 26.0 0.7 3.2e-05 23.9 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS81262.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETS81262.1 - 0.00029 19.7 0.0 0.00076 18.4 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 ETS81262.1 - 0.00091 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.9 ETS81262.1 - 0.0016 17.8 0.0 0.0062 15.8 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) zf-C2H2_4 PF13894.1 ETS81262.1 - 0.0023 18.1 20.1 1.1 9.7 0.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger Abhydrolase_6 PF12697.2 ETS81262.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS81262.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein KAP_NTPase PF07693.9 ETS81262.1 - 0.013 14.5 0.1 0.93 8.4 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 ETS81262.1 - 0.034 14.4 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 ETS81262.1 - 0.035 13.0 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 ETS81262.1 - 0.044 12.8 0.1 0.12 11.5 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.11 ETS81262.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Abhydrolase_5 PF12695.2 ETS81262.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Arch_ATPase PF01637.13 ETS81262.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 ETS81262.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M16 PF00675.15 ETS81263.1 - 2.9e-56 189.3 0.2 1.3e-55 187.2 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 ETS81263.1 - 7.8e-37 126.7 0.0 1.7e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Esterase PF00756.15 ETS81263.1 - 0.059 12.7 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Raffinose_syn PF05691.7 ETS81264.1 - 4.8e-60 202.9 1.2 1.6e-46 158.2 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 ETS81264.1 - 0.00012 20.8 0.6 0.00019 20.2 0.4 1.2 1 0 0 1 1 1 1 Melibiase Epimerase PF01370.16 ETS81265.1 - 4.3e-10 39.4 0.0 0.00029 20.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 ETS81265.1 - 4.2e-05 23.8 0.0 0.00011 22.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS81265.1 - 0.00015 20.5 0.0 0.054 12.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS81265.1 - 0.00048 20.1 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS81265.1 - 0.031 13.5 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 ETS81265.1 - 0.048 12.5 0.0 0.15 10.9 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 ETS81266.1 - 1.3e-17 64.0 0.0 4.7e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS81266.1 - 5.2e-14 52.6 0.1 1.1e-13 51.5 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS81266.1 - 7.4e-13 47.8 0.0 5e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 ETS81266.1 - 2.3e-07 30.3 0.0 8.1e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 ETS81266.1 - 7.9e-07 28.2 0.0 3e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS81266.1 - 5.9e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS81266.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS81266.1 - 0.088 12.4 0.1 0.56 9.8 0.1 2.1 1 1 0 1 1 1 0 KR domain Tautomerase_3 PF14832.1 ETS81267.1 - 1e-52 177.7 0.0 1.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme ABC_tran PF00005.22 ETS81268.1 - 4.4e-46 156.5 0.0 1.1e-26 93.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS81268.1 - 8.8e-32 110.6 38.0 6.6e-27 94.6 10.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS81268.1 - 8.4e-11 42.3 0.0 0.027 14.4 0.0 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 ETS81268.1 - 1.9e-08 33.7 6.8 0.0016 17.7 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 ETS81268.1 - 3.8e-05 23.6 0.1 0.087 12.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 ETS81268.1 - 0.00012 21.5 0.0 0.36 10.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 ETS81268.1 - 0.00015 21.2 1.9 0.47 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 ETS81268.1 - 0.00024 20.3 0.8 0.012 14.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS81268.1 - 0.00051 20.0 0.1 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS81268.1 - 0.0016 18.5 0.4 0.29 11.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 ETS81268.1 - 0.0019 18.0 0.0 0.052 13.4 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_10 PF12846.2 ETS81268.1 - 0.0037 16.7 1.5 0.25 10.7 0.0 2.6 3 0 0 3 3 3 1 AAA-like domain cobW PF02492.14 ETS81268.1 - 0.004 16.6 2.5 1.1 8.7 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 ETS81268.1 - 0.0072 16.6 0.1 2 8.7 0.0 2.8 2 1 0 3 3 2 1 AAA domain Miro PF08477.8 ETS81268.1 - 0.0085 16.5 0.9 4 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 ETS81268.1 - 0.015 14.2 0.3 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 ETS81268.1 - 0.017 15.9 0.3 1.1 10.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS81268.1 - 0.018 14.7 0.1 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 ETS81268.1 - 0.023 14.1 0.3 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 ETS81268.1 - 0.03 13.2 0.2 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 ETS81268.1 - 0.032 14.1 0.2 5.9 6.8 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 ETS81268.1 - 0.039 13.4 1.5 1.4 8.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 ETS81268.1 - 0.043 14.0 0.1 0.66 10.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 ETS81268.1 - 0.06 13.6 2.4 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS81268.1 - 0.098 11.7 0.2 6.1 5.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.10 ETS81268.1 - 0.15 10.6 0.4 0.39 9.3 0.0 1.8 3 0 0 3 3 3 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 ETS81268.1 - 0.19 11.5 4.3 0.47 10.2 0.2 2.8 2 1 0 3 3 3 0 Dynamin family MobB PF03205.9 ETS81268.1 - 0.31 10.7 3.3 7.6 6.2 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 ETS81268.1 - 0.68 9.7 2.6 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 FAD_binding_4 PF01565.18 ETS81274.1 - 3.1e-21 75.2 3.6 7.2e-21 74.1 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS81274.1 - 0.00056 19.7 0.1 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 ETS81275.1 - 5.3e-19 68.7 2.5 7.9e-16 58.4 1.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GATase PF00117.23 ETS81276.1 - 0.019 14.3 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I MFS_1 PF07690.11 ETS81277.1 - 2.7e-27 95.4 33.8 2.7e-27 95.4 23.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 ETS81279.1 - 0.56 9.4 6.4 1.3 8.2 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF21 Collar PF07484.7 ETS81280.1 - 5.1e-37 125.4 10.5 5.1e-15 55.0 1.0 4.1 3 1 0 3 3 3 3 Phage Tail Collar Domain Acetyltransf_7 PF13508.1 ETS81281.1 - 6.4e-09 35.8 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS81281.1 - 1.3e-08 34.7 0.1 9e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS81281.1 - 0.069 13.2 0.2 0.15 12.2 0.2 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 ETS81283.1 - 3.6e-34 116.9 0.0 1.6e-09 37.9 0.0 5.2 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81283.1 - 3.4e-28 96.0 0.1 0.0011 18.7 0.0 7.8 8 1 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 ETS81283.1 - 6.2e-22 75.4 0.2 0.029 14.5 0.0 9.1 9 1 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 ETS81283.1 - 4.9e-21 74.6 1.5 0.00034 21.0 0.0 7.5 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81283.1 - 1.3e-14 53.9 7.3 0.027 14.7 0.1 8.5 6 2 3 9 9 9 4 Ankyrin repeats (many copies) DUF3631 PF12307.3 ETS81283.1 - 0.025 14.4 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Epimerase PF01370.16 ETS81284.1 - 5.3e-11 42.4 0.0 6.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS81284.1 - 1.5e-08 33.6 0.0 1.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS81284.1 - 5.4e-07 29.7 0.0 2.6e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS81284.1 - 0.00039 19.7 0.0 0.00055 19.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 ETS81284.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS81284.1 - 0.03 13.2 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 ETS81285.1 - 8.1e-13 48.3 0.1 4.6e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS81285.1 - 4.2e-09 36.6 0.0 1.1e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS81285.1 - 2.6e-08 32.8 0.0 4.9e-08 32.0 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS81285.1 - 0.0036 16.2 0.0 0.016 14.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 ETS81285.1 - 0.0043 16.3 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 ETS81285.1 - 0.006 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.20 ETS81286.1 - 6.1e-70 235.3 0.0 7.4e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81286.1 - 2.2e-30 105.5 0.0 3.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS81286.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 ETS81286.1 - 0.03 13.3 0.0 0.066 12.2 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1713 PF08213.6 ETS81287.1 - 1.1e-12 47.3 21.6 1.1e-12 47.3 15.0 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Arginase PF00491.16 ETS81288.1 - 1.3e-77 260.8 0.3 1.6e-77 260.5 0.2 1.0 1 0 0 1 1 1 1 Arginase family APH PF01636.18 ETS81289.1 - 6.8e-19 68.5 0.2 8.5e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS81289.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 ETS81289.1 - 0.058 12.5 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Thioredoxin_4 PF13462.1 ETS81290.1 - 1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 ETS81290.1 - 0.061 12.8 5.0 2.5 7.5 0.1 2.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Mur_ligase_M PF08245.7 ETS81292.1 - 0.0096 15.9 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 ETS81292.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_C PF02875.16 ETS81293.1 - 0.019 15.0 0.2 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 ETS81293.1 - 0.052 13.5 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Mur ligase middle domain Succ_CoA_lig PF13607.1 ETS81293.1 - 0.098 12.2 0.7 0.28 10.7 0.5 1.7 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain CTP_synth_N PF06418.9 ETS81294.1 - 2e-100 335.4 0.0 2.8e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 ETS81294.1 - 2.2e-53 180.5 0.0 3.1e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETS81294.1 - 7.4e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 ETS81294.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Gly-rich_Ago1 PF12764.2 ETS81295.1 - 0.039 14.5 4.6 0.046 14.3 3.2 1.0 1 0 0 1 1 1 0 Glycine-rich region of argonaut FXR1P_C PF12235.3 ETS81295.1 - 0.3 11.1 2.4 0.32 11.0 1.7 1.0 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Daxx PF03344.10 ETS81296.1 - 2.3 6.5 10.4 3 6.2 7.2 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 ETS81296.1 - 3.2 6.9 14.2 5.5 6.1 9.9 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 ETS81296.1 - 6.8 4.4 12.4 9.7 3.9 8.6 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 ETS81297.1 - 1.8e-35 122.3 30.2 6.9e-35 120.3 20.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS81297.1 - 0.1 12.6 3.6 2.6 8.1 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) AMP-binding PF00501.23 ETS81298.1 - 4.4e-78 262.5 0.0 5.2e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS81298.1 - 3.9e-15 56.5 0.0 8.8e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTCB-BRCT PF12738.2 ETS81299.1 - 0.00054 19.7 0.1 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 ETS81299.1 - 0.0022 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.8 ETS81300.1 - 0.00049 19.6 0.0 0.0061 16.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain EHN PF06441.7 ETS81301.1 - 8.2e-38 128.7 0.3 1.6e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS81301.1 - 1.1e-06 28.6 10.0 1.1e-06 28.6 6.9 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family PC4 PF02229.11 ETS81302.1 - 3.1e-21 74.3 0.4 5.3e-21 73.6 0.3 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.6 ETS81302.1 - 5 7.8 11.7 6.3 7.5 1.2 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region PXA PF02194.10 ETS81303.1 - 1.2e-36 126.0 0.0 1.2e-36 126.0 0.0 2.4 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 ETS81303.1 - 7.6e-19 67.8 1.9 1.9e-18 66.6 0.0 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 ETS81303.1 - 4.5e-05 23.2 0.0 0.0003 20.5 0.0 2.3 2 0 0 2 2 2 1 PX domain Uteroglobin PF01099.12 ETS81303.1 - 0.24 11.2 1.4 4.4 7.1 0.7 2.6 2 0 0 2 2 2 0 Uteroglobin family SnoaL_2 PF12680.2 ETS81305.1 - 0.0016 18.8 0.6 0.0062 16.9 0.2 1.9 1 1 1 2 2 2 1 SnoaL-like domain TcdA_TcdB_pore PF12920.2 ETS81307.1 - 0.033 12.1 0.9 0.053 11.4 0.6 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain bZIP_1 PF00170.16 ETS81308.1 - 2.3e-09 37.0 3.1 2.3e-09 37.0 2.1 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 ETS81308.1 - 2.1e-05 24.2 3.4 2.1e-05 24.2 2.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper IncA PF04156.9 ETS81308.1 - 0.01 15.4 1.7 0.011 15.3 1.2 1.1 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 ETS81308.1 - 0.011 15.9 6.2 0.021 15.1 4.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Ndc1_Nup PF09531.5 ETS81308.1 - 0.66 8.3 2.9 0.73 8.1 2.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_12 PF13424.1 ETS81309.1 - 1.1e-11 44.4 6.1 0.00054 19.8 0.1 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS81309.1 - 3.3e-08 33.0 4.6 0.2 11.2 0.1 3.5 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETS81309.1 - 2.4e-06 26.8 0.6 0.41 10.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS81309.1 - 1.3e-05 24.7 6.3 0.069 13.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS81309.1 - 3.4e-05 23.2 5.5 0.56 9.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS81309.1 - 0.013 15.2 4.6 0.063 13.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS81309.1 - 0.019 15.5 6.5 1.5 9.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS81309.1 - 0.51 10.3 6.8 2 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.23 ETS81310.1 - 6.3e-15 54.7 0.1 7.7e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.21 ETS81311.1 - 3.9e-06 26.8 29.6 0.036 14.4 4.9 6.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS81311.1 - 7.4e-06 25.9 30.4 0.019 15.2 2.0 6.3 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS81311.1 - 1.2 9.4 24.9 2.6 8.2 0.5 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 ETS81312.1 - 1.3e-05 25.2 15.0 0.049 13.9 0.5 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS81312.1 - 0.00087 19.5 15.9 0.013 15.7 0.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETS81312.1 - 0.076 13.1 8.5 0.22 11.6 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 ETS81312.1 - 0.13 12.6 0.2 0.13 12.6 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.2 ETS81312.1 - 0.23 11.7 5.2 7.3 6.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Glyco_hydro_43 PF04616.9 ETS81313.1 - 0.0046 16.0 2.5 0.02 13.9 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 ETS81313.1 - 0.039 13.3 0.0 0.095 12.0 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DAO PF01266.19 ETS81314.1 - 1.9e-37 129.0 0.6 2.3e-37 128.7 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS81314.1 - 0.00028 21.0 0.0 0.2 11.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS81314.1 - 0.00095 18.9 0.4 0.091 12.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS81314.1 - 0.0043 17.0 0.2 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS81314.1 - 0.0094 15.8 0.2 0.018 14.9 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81314.1 - 0.0095 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 ETS81314.1 - 0.02 13.8 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 ETS81314.1 - 0.069 12.0 0.1 0.17 10.7 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3328 PF11807.3 ETS81316.1 - 1.3e-26 93.6 0.7 1.8e-26 93.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SKG6 PF08693.5 ETS81317.1 - 2.5 7.5 5.2 1.6 8.0 0.6 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4131 PF13567.1 ETS81317.1 - 8.9 5.6 10.3 2.1 7.7 3.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_1 PF00583.19 ETS81318.1 - 9.1e-06 25.6 0.1 2.5e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS81318.1 - 0.0007 19.6 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS81318.1 - 0.0094 15.8 0.9 0.035 13.9 0.4 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS81318.1 - 0.038 14.1 0.1 0.12 12.5 0.0 1.9 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 ETS81318.1 - 0.18 11.7 1.3 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.9 ETS81319.1 - 8.3e-22 78.0 0.0 1.3e-21 77.4 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS81319.1 - 4.3e-09 35.3 0.1 4e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 ETS81319.1 - 3.4e-08 33.3 0.0 0.0055 16.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS81319.1 - 7e-06 25.1 0.0 2.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS81319.1 - 9.1e-06 25.6 0.0 2.7e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS81319.1 - 1.1e-05 24.5 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS81319.1 - 0.00011 21.4 0.4 0.092 11.8 0.0 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS81319.1 - 0.00031 19.9 0.1 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 ETS81319.1 - 0.00044 19.2 4.8 0.0031 16.4 0.2 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS81319.1 - 0.00048 20.2 0.0 0.13 12.2 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS81319.1 - 0.00056 19.0 0.1 0.001 18.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS81319.1 - 0.00057 20.2 0.9 0.038 14.3 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS81319.1 - 0.0044 15.7 0.0 0.0061 15.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase 3HCDH_N PF02737.13 ETS81319.1 - 0.019 14.6 0.1 0.078 12.6 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mononeg_mRNAcap PF14318.1 ETS81319.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Lycopene_cycl PF05834.7 ETS81319.1 - 0.022 13.6 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 ETS81319.1 - 0.022 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 ETS81319.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 ETS81319.1 - 0.03 14.5 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS81319.1 - 0.035 13.4 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 ETS81319.1 - 0.042 12.9 0.3 0.042 12.9 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS81319.1 - 0.043 12.7 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IncFII_repA PF02387.10 ETS81319.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family MFS_1 PF07690.11 ETS81320.1 - 5.1e-37 127.4 54.1 5.1e-37 127.4 37.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Transgly_assoc PF04226.8 ETS81320.1 - 7.9 6.6 19.7 0.17 12.0 2.4 4.2 3 0 0 3 3 3 0 Transglycosylase associated protein Sulfatase PF00884.18 ETS81321.1 - 8.9e-42 143.3 1.8 1.4e-41 142.7 1.3 1.2 1 0 0 1 1 1 1 Sulfatase DUF2330 PF10092.4 ETS81321.1 - 0.013 14.3 0.2 0.045 12.5 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) YscK PF06578.7 ETS81321.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Sugar_tr PF00083.19 ETS81323.1 - 4.1e-68 229.9 24.8 4.7e-68 229.8 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81323.1 - 1e-12 47.5 40.1 2.3e-12 46.3 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS81323.1 - 0.00012 20.6 26.7 0.0038 15.6 7.3 3.1 3 1 1 4 4 4 2 MFS/sugar transport protein GLE1 PF07817.8 ETS81323.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein Peptidase_C14 PF00656.17 ETS81324.1 - 0.041 13.5 0.0 0.086 12.5 0.0 1.6 1 1 0 1 1 1 0 Caspase domain PBP1_TM PF14812.1 ETS81326.1 - 7.2 6.9 8.2 10 6.5 5.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 ETS81327.1 - 7.4e-20 71.8 1.7 1e-19 71.3 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81327.1 - 8.4e-11 41.8 0.4 2.6e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS81327.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS81327.1 - 0.00084 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 ETS81327.1 - 0.0053 17.0 0.1 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 ETS81327.1 - 0.069 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PLDc PF00614.17 ETS81328.1 - 5.3e-17 61.0 1.4 1.1e-07 31.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 ETS81328.1 - 2.4e-12 46.6 0.1 1.2e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 ETS81328.1 - 1.3e-07 31.3 0.0 9.6e-07 28.5 0.0 2.5 2 1 0 2 2 2 1 PX domain FlxA PF14282.1 ETS81329.1 - 0.017 15.0 5.9 0.017 15.0 4.1 6.4 2 1 3 5 5 5 0 FlxA-like protein HrpB7 PF09486.5 ETS81329.1 - 0.046 13.6 0.3 0.046 13.6 0.2 6.1 5 2 2 7 7 7 0 Bacterial type III secretion protein (HrpB7) Mannitol_dh_C PF08125.8 ETS81329.1 - 0.34 10.0 5.6 0.76 8.8 3.9 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain Reo_sigmaC PF04582.7 ETS81329.1 - 3.7 6.6 16.6 0.38 9.8 5.6 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 ETS81329.1 - 5.5 6.8 88.3 0.4 10.5 8.0 7.6 5 2 2 7 7 7 0 TATA element modulatory factor 1 DNA binding TMCO5 PF14992.1 ETS81329.1 - 8.3 5.4 59.1 0.45 9.5 11.4 4.8 3 1 2 5 5 5 0 TMCO5 family DUF465 PF04325.8 ETS81329.1 - 8.6 6.1 28.6 3.1 7.5 0.8 5.1 4 1 0 4 4 4 0 Protein of unknown function (DUF465) PGP_phosphatase PF09419.5 ETS81330.1 - 0.048 13.0 0.0 0.064 12.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase HAD_2 PF13419.1 ETS81330.1 - 0.052 13.7 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS81331.1 - 1.8e-06 27.5 0.5 2.8e-06 26.9 0.3 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 ETS81331.1 - 0.013 15.7 0.0 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 ETS81332.1 - 3.1e-60 203.5 0.0 4.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81332.1 - 1.1e-38 132.8 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS81332.1 - 3.1e-05 23.0 0.0 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 ETS81332.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.1 ETS81333.1 - 2.4e-79 265.4 0.3 2.4e-79 265.4 0.2 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 ETS81333.1 - 9.6e-35 119.1 4.8 9.6e-35 119.1 3.4 4.1 4 0 0 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 ETS81333.1 - 1.4e-30 105.8 0.0 4.8e-30 104.1 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 ETS81333.1 - 6.3e-30 103.3 0.0 1.5e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 ETS81333.1 - 9.6e-24 83.3 29.7 9.6e-24 83.3 20.6 6.3 4 1 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 ETS81333.1 - 1e-16 60.9 3.8 8.3e-16 58.0 2.7 2.4 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 ETS81333.1 - 1.8e-07 31.1 0.8 7.2e-07 29.2 0.3 2.2 2 0 0 2 2 2 1 S1 RNA binding domain SH2 PF00017.19 ETS81333.1 - 5.8e-06 26.0 0.0 1.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 ETS81333.1 - 0.007 16.2 0.1 0.039 13.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif Trypan_glycop PF00913.14 ETS81333.1 - 0.32 9.8 0.6 0.58 9.0 0.4 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Oxysterol_BP PF01237.13 ETS81334.1 - 4.7e-111 370.7 0.0 9.1e-111 369.7 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 ETS81334.1 - 3.7e-38 129.4 0.9 1.3e-37 127.7 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 ETS81334.1 - 0.00015 21.8 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETS81334.1 - 0.089 13.0 1.7 2.1 8.6 1.2 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain DDHD PF02862.12 ETS81335.1 - 6.6e-72 241.9 0.8 6.6e-72 241.9 0.5 3.9 2 2 0 2 2 2 1 DDHD domain DUF2305 PF10230.4 ETS81335.1 - 0.032 13.6 1.6 0.089 12.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 ETS81335.1 - 0.053 13.2 0.0 0.63 9.7 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family zf-CCHC PF00098.18 ETS81336.1 - 1.2e-53 176.6 63.4 2.2e-09 36.7 2.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 ETS81336.1 - 6.7e-13 48.0 45.8 0.023 14.3 0.3 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 ETS81336.1 - 1e-07 31.2 48.1 0.012 15.1 0.5 7.2 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 ETS81336.1 - 6.3e-07 29.0 53.7 0.066 12.9 0.3 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 ETS81336.1 - 0.0068 16.0 50.1 0.084 12.5 0.9 7.0 5 2 2 7 7 7 4 Zinc knuckle RMF PF04957.7 ETS81336.1 - 3.1 7.5 20.8 0.14 11.9 0.9 4.8 3 2 2 5 5 5 0 Ribosome modulation factor SAE2 PF08573.5 ETS81337.1 - 1.7e-16 60.7 0.0 1.7e-16 60.7 0.0 3.1 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CENP-Q PF13094.1 ETS81337.1 - 0.0073 16.3 5.4 0.0073 16.3 3.8 2.8 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Sipho_Gp157 PF05565.6 ETS81337.1 - 0.37 10.3 6.6 0.14 11.7 0.7 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Ax_dynein_light PF10211.4 ETS81337.1 - 0.37 10.6 14.7 0.11 12.3 0.5 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain KLRAQ PF10205.4 ETS81337.1 - 0.97 9.5 12.2 0.48 10.4 3.0 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein FlgM PF04316.8 ETS81337.1 - 2.7 8.0 7.3 0.13 12.1 0.8 2.0 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM BLOC1_2 PF10046.4 ETS81337.1 - 5.7 7.1 9.0 6.4 6.9 1.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UCH PF00443.24 ETS81338.1 - 6.5e-47 159.8 0.0 1.1e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS81338.1 - 5.8e-18 65.3 0.0 1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF844 PF05815.6 ETS81338.1 - 0.13 11.1 0.0 0.3 9.8 0.0 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) MFS_1 PF07690.11 ETS81339.1 - 7.6e-29 100.5 32.1 1e-28 100.0 22.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 ETS81340.1 - 8.9e-16 57.7 0.0 1.7e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS81340.1 - 0.0029 16.2 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ICL PF00463.16 ETS81341.1 - 8.9e-115 383.8 0.2 1e-114 383.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 ETS81341.1 - 2.5e-08 33.4 0.0 4.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NPP1 PF05630.6 ETS81343.1 - 2.6e-61 206.9 0.0 3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Aa_trans PF01490.13 ETS81344.1 - 2e-20 72.6 17.4 2.5e-20 72.3 12.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2975 PF11188.3 ETS81344.1 - 0.014 15.1 3.5 0.014 15.1 2.4 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF2975) GNVR PF13807.1 ETS81344.1 - 0.091 12.5 0.0 0.35 10.6 0.0 2.1 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF912 PF06024.7 ETS81344.1 - 0.18 11.8 0.1 0.98 9.5 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GWT1 PF06423.7 ETS81344.1 - 2.6 8.1 12.1 0.24 11.4 2.8 2.7 2 1 1 3 3 3 0 GWT1 GP41 PF00517.12 ETS81344.1 - 5.2 6.5 8.7 20 4.6 2.6 2.6 2 0 0 2 2 2 0 Retroviral envelope protein Aa_trans PF01490.13 ETS81345.1 - 0.04 12.4 0.1 0.044 12.2 0.1 1.0 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein MARVEL PF01284.18 ETS81346.1 - 5.8e-19 68.3 17.6 7.5e-19 67.9 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3687 PF12459.3 ETS81346.1 - 0.038 13.2 1.1 1.5 8.1 0.2 2.5 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein HemY_N PF07219.8 ETS81346.1 - 0.059 12.9 0.1 0.059 12.9 0.1 2.6 2 1 0 2 2 2 0 HemY protein N-terminus ABC2_membrane_5 PF13346.1 ETS81346.1 - 0.076 12.3 9.4 0.089 12.0 6.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Polysacc_synt_C PF14667.1 ETS81346.1 - 0.1 12.4 8.7 1.1 9.0 4.7 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain YpzI PF14140.1 ETS81347.1 - 3.1 7.3 7.8 21 4.6 0.0 3.9 4 0 0 4 4 4 0 YpzI-like protein HMGL-like PF00682.14 ETS81348.1 - 1.4e-70 237.6 0.7 2.1e-70 237.0 0.5 1.3 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.23 ETS81349.1 - 3.2e-100 335.4 0.0 4.8e-100 334.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 ETS81349.1 - 1.8e-85 286.5 0.1 3e-85 285.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS81349.1 - 7.8e-59 198.3 0.7 2e-55 187.2 0.1 3.0 2 0 0 2 2 2 2 KR domain Acyl_transf_1 PF00698.16 ETS81349.1 - 2e-55 188.3 0.1 3.4e-55 187.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 ETS81349.1 - 5.9e-54 182.6 0.1 1.5e-51 174.6 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 ETS81349.1 - 3.3e-51 173.5 3.6 6.7e-48 162.7 0.2 3.5 3 1 0 3 3 3 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS81349.1 - 1.3e-42 144.4 1.5 3.2e-42 143.1 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 ETS81349.1 - 3.6e-24 84.8 0.1 4.7e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 ETS81349.1 - 7.1e-16 58.3 0.1 1.4e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 ETS81349.1 - 1.6e-10 41.7 0.0 4.3e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 ETS81349.1 - 1.1e-09 37.4 0.0 0.0011 17.6 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 ETS81349.1 - 2.5e-06 26.6 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 ETS81349.1 - 0.0003 20.8 0.1 0.035 14.0 0.0 3.3 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS81349.1 - 0.001 18.0 0.0 0.077 11.8 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 ETS81349.1 - 0.039 13.2 1.5 0.97 8.6 0.1 2.9 3 0 0 3 3 3 0 NmrA-like family NmrA PF05368.8 ETS81350.1 - 4.5e-10 39.1 0.0 4.7e-09 35.8 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.16 ETS81350.1 - 0.0057 16.1 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS81350.1 - 0.051 12.4 0.2 0.078 11.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PhyH PF05721.8 ETS81351.1 - 9.1e-14 51.9 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.1 ETS81352.1 - 4.1e-30 104.6 45.6 5.2e-30 104.3 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS81352.1 - 6.5e-14 51.1 39.6 8.6e-14 50.7 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.1 ETS81353.1 - 1.7e-21 76.9 0.0 2.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS81353.1 - 2e-13 50.4 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P5CR_dimer PF14748.1 ETS81354.1 - 8e-26 90.1 0.6 1.5e-25 89.3 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 ETS81354.1 - 9.7e-05 22.7 0.0 0.00035 20.9 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 ETS81355.1 - 8.4e-51 172.9 0.1 9.8e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS81355.1 - 9.4e-05 22.5 0.2 0.0062 16.6 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS81355.1 - 0.0006 19.6 2.5 0.37 10.5 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 ETS81355.1 - 0.019 14.0 0.2 1.9 7.5 0.0 2.7 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 ETS81355.1 - 0.028 12.9 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Carb_kinase PF01256.12 ETS81355.1 - 0.032 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase ALG3 PF05208.8 ETS81355.1 - 0.046 12.9 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 ALG3 protein FAD_binding_2 PF00890.19 ETS81355.1 - 0.052 12.3 4.0 0.49 9.1 2.8 2.1 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 ETS81355.1 - 0.14 11.0 0.1 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.11 ETS81356.1 - 7.8e-20 70.8 75.1 1.7e-14 53.3 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 ETS81357.1 - 6.4e-06 25.9 9.6 1e-05 25.3 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2422 PF10337.4 ETS81358.1 - 4.1e-85 286.2 8.5 7.2e-85 285.4 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 ETS81358.1 - 7.8e-31 107.4 0.0 1.4e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 ETS81358.1 - 5e-09 36.1 13.4 5e-09 36.1 9.3 3.4 2 1 0 2 2 2 1 Fusaric acid resistance protein-like p450 PF00067.17 ETS81359.1 - 4.1e-72 243.1 0.0 5.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.19 ETS81360.1 - 3.1e-14 53.3 0.0 2.1e-08 34.4 0.0 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS81360.1 - 0.00011 21.5 0.2 0.0041 16.6 0.1 2.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS81360.1 - 0.011 16.0 0.0 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain GAF_2 PF13185.1 ETS81361.1 - 0.012 16.0 0.1 0.12 12.8 0.1 2.1 1 1 0 1 1 1 0 GAF domain CN_hydrolase PF00795.17 ETS81362.1 - 4.2e-32 111.0 0.0 7.8e-32 110.1 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.12 ETS81363.1 - 3.2e-95 317.7 0.1 3.9e-95 317.4 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 ETS81363.1 - 9.1e-06 25.3 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81363.1 - 1.5e-05 25.4 0.0 2.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 ETS81363.1 - 0.0046 15.9 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 ETS81363.1 - 0.0096 15.1 0.1 0.12 11.5 0.0 2.4 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 ETS81363.1 - 0.07 12.8 0.0 0.21 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.15 ETS81364.1 - 4e-115 384.6 1.3 4.7e-115 384.3 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS81364.1 - 1.8e-13 50.1 0.4 1.7e-08 33.8 0.0 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS81364.1 - 0.0012 18.0 2.2 0.079 12.0 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 ETS81364.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETS81364.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_3 PF00933.16 ETS81365.1 - 4e-85 285.4 0.0 5.6e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS81365.1 - 3.4e-44 151.0 0.1 3.6e-43 147.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS81365.1 - 6.2e-20 70.9 0.1 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 ETS81366.1 - 8.1e-11 41.2 0.0 1.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81366.1 - 2.8e-09 36.7 9.8 5.4e-09 35.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS81368.1 - 2.3e-27 95.6 0.0 2.6e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 ETS81369.1 - 9.5e-21 74.6 0.1 1.1e-20 74.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS81369.1 - 4.7e-10 39.6 3.2 7.5e-10 38.9 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81369.1 - 2.9e-06 27.0 0.3 4.5e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS81369.1 - 0.0023 17.9 0.7 0.0043 17.0 0.5 1.5 1 0 0 1 1 1 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 ETS81369.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NmrA PF05368.8 ETS81369.1 - 0.066 12.4 0.2 0.095 11.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_tran_WecB PF03808.8 ETS81369.1 - 0.12 11.8 0.0 0.39 10.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF1373 PF07117.6 ETS81370.1 - 0.0028 17.4 2.7 0.0028 17.4 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1373) Nucleo_P87 PF07267.6 ETS81371.1 - 1.4 7.4 3.0 3.2 6.3 2.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HeLo PF14479.1 ETS81372.1 - 1.1e-24 87.4 0.5 2e-24 86.5 0.1 1.6 1 1 1 2 2 2 1 Prion-inhibition and propagation ADIP PF11559.3 ETS81374.1 - 3.6e-38 130.8 2.9 3.6e-38 130.8 2.0 3.1 5 0 0 5 5 5 1 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 ETS81374.1 - 0.0063 16.5 5.1 0.0063 16.5 3.5 2.9 4 0 0 4 4 4 1 Ciliary rootlet component, centrosome cohesion DUF484 PF04340.7 ETS81374.1 - 0.024 14.0 4.0 0.075 12.4 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF484 IncA PF04156.9 ETS81374.1 - 0.82 9.2 11.2 0.019 14.5 1.6 2.5 2 1 0 2 2 2 0 IncA protein ATG16 PF08614.6 ETS81374.1 - 3.5 7.3 13.9 0.79 9.5 3.8 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Amino_oxidase PF01593.19 ETS81375.1 - 3.5e-37 128.5 0.0 1.4e-35 123.2 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS81375.1 - 1.1e-13 50.9 0.1 2.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS81375.1 - 1.2e-05 25.4 0.1 0.00063 19.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS81375.1 - 4.6e-05 23.2 0.8 0.16 11.7 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 ETS81375.1 - 0.00041 18.9 0.2 0.038 12.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 ETS81375.1 - 0.00042 20.6 2.3 0.0012 19.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS81375.1 - 0.0033 16.3 0.0 0.0066 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS81375.1 - 0.0048 15.7 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS81375.1 - 0.0096 15.8 0.3 0.018 14.9 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81375.1 - 0.025 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 ETS81375.1 - 0.032 13.1 0.2 0.09 11.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Semialdhyde_dh PF01118.19 ETS81375.1 - 0.19 12.0 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATG2_CAD PF13329.1 ETS81376.1 - 0.15 11.6 0.3 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif ATG2_CAD PF13329.1 ETS81377.1 - 2.3e-42 144.2 0.2 6.6e-42 142.7 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 ETS81377.1 - 1.4e-27 95.6 0.1 4.6e-27 94.0 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain adh_short PF00106.20 ETS81378.1 - 4.5e-29 101.4 0.1 6.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81378.1 - 4.3e-18 65.9 0.0 5.3e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS81378.1 - 6.4e-12 45.4 0.6 2e-11 43.9 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81378.1 - 0.00023 20.7 0.0 0.00064 19.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 ETS81378.1 - 0.0039 17.2 0.1 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS81378.1 - 0.0049 16.6 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ETS81378.1 - 0.041 12.7 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS81378.1 - 0.045 13.7 0.2 0.36 10.8 0.0 2.2 2 1 0 2 2 2 0 NADH(P)-binding Glyco_transf_8 PF01501.15 ETS81379.1 - 9.2e-22 77.5 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Alpha-amylase PF00128.19 ETS81380.1 - 2.9e-08 33.5 0.1 9.7e-08 31.7 0.1 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3372 PF11852.3 ETS81381.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Mito_carr PF00153.22 ETS81382.1 - 3.6e-55 183.6 0.2 4.3e-19 68.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.12 ETS81383.1 - 1.4e-45 153.9 2.3 1.6e-45 153.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Aldedh PF00171.17 ETS81384.1 - 5e-73 246.0 0.0 6.1e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3222 PF11519.3 ETS81385.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) ECR1_N PF14382.1 ETS81387.1 - 9.6e-10 37.5 0.0 1.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 ETS81387.1 - 0.027 14.5 0.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 S1 RNA binding domain TMEM151 PF14857.1 ETS81387.1 - 0.086 11.4 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 TMEM151 family Pex24p PF06398.6 ETS81388.1 - 1.4e-98 329.9 0.2 1.7e-98 329.7 0.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 ETS81388.1 - 0.0016 16.3 0.3 0.0026 15.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF639 PF04842.7 ETS81388.1 - 0.38 8.8 2.6 0.26 9.4 0.2 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) PRT_C PF08372.5 ETS81388.1 - 0.77 9.2 4.3 1.3 8.5 0.4 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal polyprenyl_synt PF00348.12 ETS81389.1 - 4.5e-58 196.1 0.0 5.5e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 ETS81390.1 - 7.6e-87 290.6 0.0 9.3e-87 290.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.5 ETS81391.1 - 0.027 13.8 1.0 0.055 12.7 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3454 PF11936.3 ETS81391.1 - 0.065 13.4 4.6 0.15 12.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) HD PF01966.17 ETS81392.1 - 1.4e-05 25.1 0.1 8.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 HD domain TFIIE_alpha PF02002.12 ETS81392.1 - 0.11 12.0 0.3 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit HDOD PF08668.7 ETS81392.1 - 0.14 11.3 0.1 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 HDOD domain DUF2628 PF10947.3 ETS81394.1 - 0.033 13.9 0.2 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) VIT1 PF01988.14 ETS81394.1 - 2.5 7.5 8.3 3.7 6.9 5.8 1.2 1 0 0 1 1 1 0 VIT family Amidohydro_2 PF04909.9 ETS81397.1 - 8.2e-22 78.0 0.0 1.1e-21 77.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Glyoxalase_2 PF12681.2 ETS81398.1 - 3.6e-08 33.9 0.0 5.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 ETS81398.1 - 0.0008 19.3 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SUR7 PF06687.7 ETS81399.1 - 7.9e-41 139.9 15.3 1e-40 139.5 10.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 ETS81399.1 - 0.058 13.2 9.0 0.2 11.4 5.4 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 ETS81399.1 - 8.4 6.0 20.4 0.35 10.5 2.9 3.0 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DWNN PF08783.6 ETS81401.1 - 1.6e-28 98.4 0.0 2.9e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-RING_6 PF14835.1 ETS81401.1 - 9.9e-05 22.0 1.5 0.00019 21.1 1.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-CCHC PF00098.18 ETS81401.1 - 0.00023 20.9 0.6 0.00053 19.7 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 ETS81401.1 - 0.0023 17.3 3.5 0.0055 16.1 2.2 1.9 2 0 0 2 2 2 1 Zinc knuckle U-box PF04564.10 ETS81401.1 - 0.003 17.5 0.2 0.0098 15.8 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.1 ETS81401.1 - 0.0039 17.1 7.9 0.0039 17.1 5.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS81401.1 - 0.011 15.4 7.7 0.011 15.4 5.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 ETS81401.1 - 0.017 14.6 4.1 0.036 13.6 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 ETS81401.1 - 0.27 11.1 8.8 0.81 9.6 6.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 ETS81401.1 - 0.32 10.6 8.4 0.65 9.6 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 ETS81401.1 - 0.35 10.4 5.3 0.83 9.2 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 ETS81401.1 - 0.4 10.5 12.4 0.021 14.6 4.1 2.0 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.11 ETS81401.1 - 0.59 10.0 5.4 0.16 11.8 1.1 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.1 ETS81401.1 - 2.6 7.8 9.6 0.2 11.3 2.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.10 ETS81402.1 - 2.4e-111 371.6 0.0 2.7e-111 371.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 ETS81402.1 - 1.9e-15 56.7 0.4 5.6e-15 55.2 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS81402.1 - 5e-08 33.0 0.0 3.8e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 ETS81402.1 - 3.5e-06 26.4 0.0 8.9e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 ETS81402.1 - 3.2e-05 23.4 0.1 0.0012 18.3 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 ETS81402.1 - 0.0074 16.0 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain YhjQ PF06564.7 ETS81402.1 - 0.0082 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 ETS81402.1 - 0.013 14.8 0.1 0.026 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS81402.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 ETS81402.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 ETS81402.1 - 0.046 14.0 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 ETS81402.1 - 0.059 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 ETS81402.1 - 0.075 12.4 0.1 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 AAA-like domain DUF3502 PF12010.3 ETS81402.1 - 0.11 12.4 0.1 0.36 10.8 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3502) DUF3763 PF12592.3 ETS81402.1 - 0.17 11.5 0.4 0.77 9.4 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF3763) DPBB_1 PF03330.13 ETS81403.1 - 6.9e-06 25.9 0.6 1.7e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 ETS81403.1 - 0.00047 19.8 0.1 0.00062 19.4 0.1 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 ETS81403.1 - 0.029 14.3 0.2 0.04 13.9 0.1 1.3 1 1 0 1 1 1 0 Cerato-platanin DUF1866 PF08952.6 ETS81403.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Transthyretin PF00576.16 ETS81405.1 - 1.1e-27 96.1 1.6 1.6e-25 89.1 1.1 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family ADH_zinc_N PF00107.21 ETS81406.1 - 7e-23 80.6 0.1 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS81406.1 - 3.1e-11 44.2 0.2 1.1e-10 42.5 0.0 1.9 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS81406.1 - 7.2e-11 41.8 0.1 5.3e-10 39.0 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Translin PF01997.11 ETS81407.1 - 1.5e-47 161.7 0.0 1.8e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Translin family DASH_Duo1 PF08651.5 ETS81407.1 - 0.032 13.8 0.3 0.23 11.0 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 PIG-F PF06699.6 ETS81408.1 - 1.4e-55 188.1 4.7 1.7e-55 187.9 3.3 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 ETS81408.1 - 0.11 12.6 5.6 0.66 10.1 0.8 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 ETS81408.1 - 0.52 9.9 6.6 2.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper Beta-lactamase PF00144.19 ETS81409.1 - 2.2e-47 161.6 0.1 2.7e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETS81409.1 - 0.0012 18.1 0.0 0.0029 16.9 0.0 1.6 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PhyH PF05721.8 ETS81411.1 - 2.8e-11 43.8 0.0 3.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HlyE PF06109.8 ETS81411.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) IFRD PF05004.8 ETS81413.1 - 2.6e-33 115.4 1.1 3.6e-33 114.9 0.7 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) FHA PF00498.21 ETS81414.1 - 5.8e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain SIS PF01380.17 ETS81417.1 - 3.5e-12 46.0 0.1 9.6e-12 44.6 0.0 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 ETS81417.1 - 0.008 15.8 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 SIS domain Ribosomal_L18p PF00861.17 ETS81417.1 - 0.094 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L18p/L5e family Tet_JBP PF12851.2 ETS81417.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Claudin_2 PF13903.1 ETS81418.1 - 8.2e-10 38.6 5.1 1.1e-09 38.2 3.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 ETS81418.1 - 2.7e-07 30.7 2.7 3.8e-06 27.0 1.9 2.0 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 ETS81418.1 - 8.5e-05 22.2 6.0 0.00018 21.2 4.1 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.6 ETS81418.1 - 0.11 12.1 9.9 0.61 9.8 6.9 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SUR7 PF06687.7 ETS81418.1 - 0.4 10.2 5.7 0.08 12.4 0.3 1.9 2 0 0 2 2 2 0 SUR7/PalI family DUF2373 PF10180.4 ETS81419.1 - 3.8e-19 68.0 0.5 6.9e-19 67.1 0.2 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 ETS81420.1 - 1.2e-48 164.9 0.0 1.6e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS81420.1 - 3.5e-12 45.3 0.2 6.5e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2011 PF09428.5 ETS81421.1 - 0.035 14.0 0.1 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Ank_2 PF12796.2 ETS81422.1 - 0.00012 22.3 0.1 0.0003 21.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81422.1 - 0.01 15.6 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 ETS81422.1 - 0.023 14.9 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_2 PF13639.1 ETS81422.1 - 0.026 14.3 7.6 0.026 14.3 5.2 2.1 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 ETS81422.1 - 0.066 13.1 2.0 0.16 11.8 1.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DNA_ligase_ZBD PF03119.11 ETS81422.1 - 0.44 10.3 6.2 0.86 9.3 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_5 PF14634.1 ETS81422.1 - 0.55 10.0 4.4 2 8.1 3.1 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 ETS81422.1 - 0.68 9.5 5.0 0.25 10.9 1.0 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 ETS81422.1 - 3.1 7.8 7.7 0.33 11.0 1.6 2.1 3 0 0 3 3 3 0 RING-like domain zf-C3HC4_3 PF13920.1 ETS81422.1 - 6.9 6.4 8.1 26 4.5 5.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS81422.1 - 7.1 6.7 7.5 0.42 10.6 1.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Uds1 PF15456.1 ETS81423.1 - 1.2e-32 112.4 9.2 1.2e-32 112.4 6.4 2.8 4 0 0 4 4 4 1 Up-regulated During Septation Peptidase_M1 PF01433.15 ETS81424.1 - 4.2e-73 246.6 0.0 5.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 ETS81424.1 - 3.8e-34 117.3 0.0 7.6e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 ETS81424.1 - 1e-16 61.1 0.1 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 ETS81424.1 - 0.17 11.8 2.1 1 9.3 1.5 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ribosomal_S7 PF00177.16 ETS81424.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Glyco_hydro_6 PF01341.12 ETS81425.1 - 2.6e-94 316.0 4.1 3.3e-94 315.6 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.8 ETS81426.1 - 1.3e-20 73.6 0.5 1.8e-20 73.0 0.4 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Acyl_transf_3 PF01757.17 ETS81426.1 - 0.013 14.3 3.1 0.019 13.8 2.1 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF4131 PF13567.1 ETS81426.1 - 0.075 12.4 2.3 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 ETS81426.1 - 0.54 9.6 3.2 0.18 11.1 0.2 1.7 2 0 0 2 2 2 0 Fatty acid desaturase NPV_P10 PF05531.7 ETS81427.1 - 0.024 14.8 1.1 0.024 14.8 0.8 5.4 3 2 3 6 6 6 0 Nucleopolyhedrovirus P10 protein FtsJ PF01728.14 ETS81428.1 - 2e-61 207.1 0.0 2.4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 ETS81428.1 - 0.0007 19.3 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81428.1 - 0.14 11.7 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 ETS81429.1 - 1.3e-21 76.7 26.9 4.7e-21 74.8 18.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS81429.1 - 6.5e-06 24.6 0.9 6.5e-06 24.6 0.6 2.6 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS81430.1 - 3.9e-09 35.6 8.2 3.9e-09 35.6 5.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0239 PF06783.6 ETS81431.1 - 0.021 14.7 0.1 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) IncA PF04156.9 ETS81431.1 - 0.11 12.0 0.4 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 IncA protein DUF788 PF05620.6 ETS81431.1 - 0.49 10.2 0.0 0.49 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Glyco_hydro_3 PF00933.16 ETS81432.1 - 3e-80 269.3 0.0 4.5e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS81432.1 - 6.3e-45 153.4 0.6 2.2e-44 151.6 0.0 2.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS81432.1 - 7.9e-20 70.5 0.0 1.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Acyl-CoA_dh_1 PF00441.19 ETS81433.1 - 2e-34 118.8 0.2 3.1e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 ETS81433.1 - 7.5e-20 70.5 0.0 1.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 ETS81433.1 - 7.8e-17 60.5 0.3 1.6e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS81433.1 - 4.9e-05 23.8 0.0 0.00014 22.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS81433.1 - 0.0096 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LIP PF03583.9 ETS81434.1 - 1.6e-62 211.3 0.1 2.2e-62 210.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Lact-deh-memb PF09330.6 ETS81434.1 - 0.11 11.8 0.0 0.95 8.7 0.0 2.0 2 0 0 2 2 2 0 D-lactate dehydrogenase, membrane binding HET PF06985.6 ETS81435.1 - 1.5e-22 80.2 4.8 4.2e-22 78.7 3.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4372 PF14294.1 ETS81435.1 - 0.056 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Cut8_C PF08559.5 ETS81436.1 - 1.4e-48 164.3 0.0 2e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 ETS81436.1 - 1e-13 50.8 0.4 1.9e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 ETS81436.1 - 0.0001 22.2 3.7 0.0001 22.2 2.6 2.4 2 0 0 2 2 2 1 Cut8 proteasome-binding domain MFS_1 PF07690.11 ETS81438.1 - 1.2e-20 73.5 44.5 2.1e-14 53.0 11.4 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 ETS81440.1 - 5.2e-06 26.0 0.2 3.6e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS81440.1 - 0.0011 18.5 0.0 0.0035 16.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 ETS81440.1 - 0.0025 17.4 0.1 0.024 14.2 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 ETS81440.1 - 0.016 15.1 2.2 3 7.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat LRR_4 PF12799.2 ETS81440.1 - 0.14 11.8 4.3 11 5.7 0.0 5.1 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) p450 PF00067.17 ETS81441.1 - 9.1e-70 235.4 0.0 1.1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_5 PF07994.7 ETS81442.1 - 4e-114 381.0 0.2 4.8e-114 380.8 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 ETS81442.1 - 2.5e-45 152.8 0.6 5e-45 151.9 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.17 ETS81443.1 - 1.1e-18 67.0 18.8 6e-10 39.0 2.4 3.0 3 0 0 3 3 3 2 LIM domain AMP-binding PF00501.23 ETS81443.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme DUF3405 PF11885.3 ETS81444.1 - 2.6e-179 596.5 0.9 4.5e-179 595.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) AFG1_ATPase PF03969.11 ETS81445.1 - 4.5e-54 183.6 0.0 2.8e-25 88.9 0.0 5.0 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.1 ETS81445.1 - 0.0008 19.4 3.4 0.0073 16.3 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 ETS81445.1 - 0.00086 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS81445.1 - 0.0081 16.3 0.0 0.033 14.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS81445.1 - 0.014 15.0 0.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 ETS81445.1 - 0.074 13.3 0.3 1.5 9.1 0.1 2.2 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.1 ETS81445.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS81445.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 ETS81445.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 ETS81445.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIF1 PF05970.9 ETS81445.1 - 0.22 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Nucleoporin_C PF03177.9 ETS81446.1 - 7.5e-76 255.8 15.9 1.1e-75 255.3 11.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 ETS81446.1 - 1.6e-74 251.2 0.0 2.2e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like MatE PF01554.13 ETS81447.1 - 3.3e-51 173.1 18.6 5.7e-28 97.5 2.1 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 ETS81447.1 - 3.3e-09 36.6 0.6 3.3e-09 36.6 0.4 4.0 3 2 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.20 ETS81448.1 - 4.3e-18 65.4 0.0 1.5e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain WW PF00397.21 ETS81448.1 - 1.9e-05 24.4 1.8 0.0074 16.1 0.1 2.9 2 0 0 2 2 2 2 WW domain Pkinase_Tyr PF07714.12 ETS81448.1 - 0.00065 18.8 0.0 0.0021 17.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1237 PF06824.6 ETS81448.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) Kelch_5 PF13854.1 ETS81449.1 - 7.3e-12 44.9 1.4 3.2e-07 30.1 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 ETS81449.1 - 3.3e-05 23.4 10.5 0.34 10.7 0.1 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 ETS81449.1 - 6.4e-05 22.9 3.6 1.4 9.2 0.1 4.8 4 0 0 4 4 4 2 Kelch motif EphA2_TM PF14575.1 ETS81449.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kelch_4 PF13418.1 ETS81449.1 - 0.015 15.0 15.7 0.16 11.7 0.1 4.9 4 1 1 5 5 5 0 Galactose oxidase, central domain Alpha_GJ PF03229.8 ETS81449.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Kelch_1 PF01344.20 ETS81449.1 - 0.083 12.4 9.1 0.21 11.1 0.1 4.5 4 0 0 4 4 4 0 Kelch motif DUF4366 PF14283.1 ETS81449.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.11 ETS81449.1 - 0.2 9.8 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NACHT PF05729.7 ETS81450.1 - 8.7e-07 28.7 0.0 2.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS81450.1 - 9.5e-07 29.0 0.1 8.8e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS81450.1 - 0.0021 18.0 0.5 0.015 15.3 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain Ank_5 PF13857.1 ETS81450.1 - 0.01 16.0 0.0 1.1 9.5 0.1 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NB-ARC PF00931.17 ETS81450.1 - 0.013 14.4 0.1 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 ETS81450.1 - 0.016 15.3 0.0 0.072 13.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS81450.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain HET PF06985.6 ETS81451.1 - 1.1e-26 93.7 0.5 2e-26 92.7 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SGT1 PF07093.6 ETS81452.1 - 0.01 14.2 0.2 0.01 14.2 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.4 ETS81452.1 - 0.028 13.1 12.8 0.032 12.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 ETS81452.1 - 0.25 10.5 4.4 0.24 10.6 3.1 1.1 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 ETS81452.1 - 0.28 10.6 10.6 0.38 10.2 7.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop53 PF07767.6 ETS81452.1 - 0.54 9.1 3.3 0.66 8.9 2.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.8 ETS81452.1 - 0.57 9.7 7.7 0.88 9.1 5.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 ETS81452.1 - 0.62 10.3 13.0 1.1 9.5 9.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 ETS81452.1 - 0.68 8.8 5.6 0.76 8.7 3.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Voldacs PF03517.8 ETS81452.1 - 1 9.2 11.8 3 7.6 8.2 1.7 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling YL1 PF05764.8 ETS81452.1 - 1.7 8.2 7.3 2.2 7.8 5.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.7 ETS81452.1 - 1.8 7.7 8.6 2 7.6 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 ETS81452.1 - 2.3 8.0 5.6 3.4 7.4 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nro1 PF12753.2 ETS81452.1 - 2.4 7.0 8.2 3 6.7 5.7 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 COPI_C PF06957.6 ETS81452.1 - 2.5 6.5 4.7 3 6.2 3.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Daxx PF03344.10 ETS81452.1 - 3.3 6.0 8.2 3.6 5.9 5.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 ETS81452.1 - 3.7 5.4 7.7 4.3 5.2 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 ETS81452.1 - 5.6 4.5 7.5 6.3 4.4 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.7 ETS81452.1 - 6.5 4.5 11.3 7.1 4.4 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 ETS81452.1 - 7.4 6.1 8.7 8.3 6.0 6.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.8 ETS81452.1 - 9.3 3.8 13.2 12 3.5 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cupin_2 PF07883.6 ETS81453.1 - 3.4e-07 29.6 0.2 5.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain PS_Dcarbxylase PF02666.10 ETS81454.1 - 7.5e-54 182.1 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 ETS81454.1 - 5.3e-33 112.7 0.0 2.3e-15 56.2 0.0 2.8 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 ETS81454.1 - 0.00057 19.4 0.0 0.61 9.5 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain EF-hand_7 PF13499.1 ETS81454.1 - 0.0015 18.6 0.1 0.0059 16.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS81454.1 - 0.0025 17.0 0.4 0.0071 15.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 ETS81454.1 - 0.0067 16.2 0.5 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 ETS81454.1 - 0.044 13.1 0.0 0.15 11.4 0.0 2.0 1 0 0 1 1 1 0 EF hand PBP1_TM PF14812.1 ETS81454.1 - 0.1 12.8 5.5 0.32 11.3 3.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAD PF12710.2 ETS81455.1 - 1e-09 38.8 0.1 1.6e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 ETS81455.1 - 0.0047 16.1 0.0 0.49 9.5 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 ETS81455.1 - 0.029 14.7 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Coatomer_E PF04733.9 ETS81456.1 - 4.1e-64 216.5 9.0 4.6e-64 216.3 6.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 ETS81456.1 - 5e-10 39.5 24.6 7.7e-05 22.9 2.4 4.3 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS81456.1 - 1.6e-09 37.2 1.2 1.1e-06 28.1 0.0 3.0 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 ETS81456.1 - 3.6e-08 33.8 20.6 5.3e-07 30.1 0.5 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETS81456.1 - 2e-05 23.7 6.9 0.0016 17.6 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS81456.1 - 9.3e-05 22.7 24.5 0.00094 19.6 0.2 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS81456.1 - 0.0025 17.8 4.2 1.5 9.0 0.0 3.4 3 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Type_III_YscG PF09477.5 ETS81456.1 - 0.0029 17.6 0.4 0.0029 17.6 0.3 3.0 1 1 2 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 ETS81456.1 - 0.0071 16.0 0.4 1 9.2 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS81456.1 - 0.017 15.0 0.2 0.017 15.0 0.1 2.4 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 ETS81456.1 - 0.028 14.3 0.1 0.028 14.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETS81456.1 - 0.036 13.9 10.3 0.06 13.2 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS81456.1 - 0.075 12.9 10.3 0.46 10.4 0.5 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETS81456.1 - 0.082 13.1 1.6 4.1 7.8 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat GRDA PF04723.9 ETS81456.1 - 0.11 12.2 0.9 0.2 11.3 0.6 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A UBA_4 PF14555.1 ETS81456.1 - 0.12 11.9 0.6 7.1 6.2 0.0 2.8 2 0 0 2 2 2 0 UBA-like domain TPR_7 PF13176.1 ETS81456.1 - 0.69 9.8 8.9 6.4 6.8 0.0 5.2 5 2 1 6 6 5 0 Tetratricopeptide repeat CPL PF08144.6 ETS81456.1 - 0.83 9.4 11.1 1.5 8.6 0.8 3.6 2 2 1 3 3 3 0 CPL (NUC119) domain TPR_6 PF13174.1 ETS81456.1 - 1.6 9.3 11.3 4.3 7.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS81456.1 - 2.4 7.9 8.7 1.5 8.6 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS81456.1 - 9.3 6.3 12.4 20 5.3 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4590 PF15257.1 ETS81457.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) AAA PF00004.24 ETS81458.1 - 1.8e-17 63.7 0.0 3.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS81458.1 - 0.0013 18.8 0.0 0.0058 16.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS81458.1 - 0.0015 18.3 0.4 0.099 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS81458.1 - 0.0086 16.0 1.4 0.012 15.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 ETS81458.1 - 0.035 13.5 0.0 0.79 9.1 0.0 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 ETS81458.1 - 0.037 14.8 0.2 0.27 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 ETS81458.1 - 0.12 12.1 0.2 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 ETS81458.1 - 0.17 10.6 0.1 0.3 9.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 ETS81458.1 - 0.22 10.2 0.1 0.5 9.0 0.1 1.5 1 0 0 1 1 1 0 ArgK protein Yip1 PF04893.12 ETS81459.1 - 1.2 8.5 10.6 5.8 6.3 1.9 2.3 1 1 1 2 2 2 0 Yip1 domain Aminotran_1_2 PF00155.16 ETS81460.1 - 6.9e-66 222.6 0.0 7.8e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 ETS81460.1 - 5.8e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 ETS81460.1 - 0.0003 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETS81460.1 - 0.0022 16.3 0.0 0.0058 14.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 ETS81460.1 - 0.0024 16.6 0.0 0.0059 15.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Fungal_trans_2 PF11951.3 ETS81461.1 - 1.5e-55 188.4 0.5 1.9e-55 188.0 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS81461.1 - 0.088 11.6 0.0 0.35 9.6 0.0 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 ETS81462.1 - 4.1e-44 150.6 0.0 5.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS81462.1 - 1.3e-06 27.3 0.0 2.8e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 ETS81462.1 - 0.026 13.1 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS81462.1 - 0.031 14.0 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 ETS81463.1 - 2e-69 234.3 24.2 2.6e-69 233.9 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81463.1 - 2.1e-15 56.3 47.9 2.9e-11 42.6 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 ETS81464.1 - 8.4e-11 42.3 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS81464.1 - 4.9e-07 28.5 0.1 0.1 11.0 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) FAD-oxidase_C PF02913.14 ETS81465.1 - 1.7e-60 204.4 0.0 2.7e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS81465.1 - 4.2e-38 129.9 0.0 7.6e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 ETS81465.1 - 0.068 11.6 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Peptidase_S51 PF03575.12 ETS81466.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 HET PF06985.6 ETS81467.1 - 5.9e-34 117.1 1.2 5.9e-34 117.1 0.9 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS81467.1 - 1.1e-06 28.8 1.3 0.47 10.8 0.0 4.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) MFS_1 PF07690.11 ETS81469.1 - 4.2e-32 111.2 25.1 4.2e-32 111.2 17.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 ETS81469.1 - 8.3 5.1 30.6 0.016 14.0 6.7 3.1 2 1 0 2 2 2 0 Acyltransferase family Acetyltransf_1 PF00583.19 ETS81470.1 - 3.5e-06 26.9 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS81470.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS81470.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_61 PF03443.9 ETS81471.1 - 2.9e-45 154.7 0.6 3.3e-45 154.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_11 PF08241.7 ETS81472.1 - 3.8e-14 52.9 0.0 6.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81472.1 - 3.4e-13 50.1 0.0 1.8e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS81472.1 - 4.9e-11 42.6 0.0 7.4e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81472.1 - 2.8e-09 36.7 0.0 4.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81472.1 - 3.6e-09 36.9 0.0 9.3e-09 35.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81472.1 - 4.1e-09 36.7 0.0 7.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS81472.1 - 3.6e-07 30.2 0.0 7.6e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS81472.1 - 2.8e-06 26.6 0.0 4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS81472.1 - 1.6e-05 24.3 0.0 5.5e-05 22.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 ETS81472.1 - 0.00012 21.3 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 ETS81472.1 - 0.0016 17.7 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CheR PF01739.13 ETS81472.1 - 0.012 14.9 0.0 0.54 9.5 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PCMT PF01135.14 ETS81472.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 ETS81472.1 - 0.019 14.4 0.0 0.045 13.1 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.4 ETS81472.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 ETS81472.1 - 0.053 12.6 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 ETS81472.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 ETS81472.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Amidase02_C PF12123.3 ETS81472.1 - 2.4 7.8 6.2 9.1 6.0 2.2 2.9 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase BNR PF02012.15 ETS81473.1 - 0.091 12.6 0.5 0.61 10.1 0.0 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat Queuosine_synth PF02547.10 ETS81474.1 - 0.091 11.4 0.4 0.087 11.5 0.3 1.0 1 0 0 1 1 1 0 Queuosine biosynthesis protein Methyltransf_23 PF13489.1 ETS81475.1 - 1.9e-17 63.4 0.0 3.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-His_Me_endon PF05551.6 ETS81475.1 - 4e-14 52.7 2.9 8.5e-14 51.6 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Methyltransf_31 PF13847.1 ETS81475.1 - 6.3e-07 29.1 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81475.1 - 7.7e-07 29.6 0.0 4.8e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81475.1 - 2.4e-05 24.6 0.0 0.00011 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81475.1 - 3.8e-05 24.0 0.0 0.00013 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain zf-C2H2_4 PF13894.1 ETS81475.1 - 0.00046 20.3 3.9 0.098 13.0 1.0 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger Methyltransf_25 PF13649.1 ETS81475.1 - 0.018 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 ETS81475.1 - 0.055 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 ETS81475.1 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 ETS81475.1 - 0.15 11.1 0.0 0.38 9.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-C2H2 PF00096.21 ETS81475.1 - 0.21 12.0 2.3 0.6 10.5 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3716 PF12511.3 ETS81477.1 - 0.00011 21.7 11.7 0.00018 21.0 8.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TFIIE-A_C-term PF11521.3 ETS81477.1 - 1 9.3 5.0 2.2 8.2 3.5 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha ADP_PFK_GK PF04587.10 ETS81478.1 - 0.0041 15.3 0.0 0.0053 15.0 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region zf-C2H2 PF00096.21 ETS81479.1 - 0.0071 16.6 0.8 0.0071 16.6 0.6 10.7 12 0 0 12 12 12 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETS81479.1 - 0.16 12.1 0.1 0.16 12.1 0.1 8.1 9 1 1 10 10 10 0 Zinc-finger double-stranded RNA-binding OEP PF02321.13 ETS81484.1 - 0.0029 17.2 0.9 0.0044 16.6 0.6 1.2 1 0 0 1 1 1 1 Outer membrane efflux protein DUF869 PF05911.6 ETS81484.1 - 0.0076 14.5 0.2 0.0079 14.4 0.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Rootletin PF15035.1 ETS81484.1 - 0.02 14.8 1.2 0.026 14.5 0.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 ETS81484.1 - 0.029 13.5 3.0 0.042 13.0 2.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETS81484.1 - 0.04 13.5 0.4 0.045 13.3 0.3 1.2 1 0 0 1 1 1 0 IncA protein UPF0449 PF15136.1 ETS81484.1 - 0.15 12.2 1.0 0.5 10.6 0.4 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF3861 PF12977.2 ETS81485.1 - 0.016 15.3 0.4 0.016 15.3 0.3 2.9 2 2 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) GP41 PF00517.12 ETS81485.1 - 0.045 13.3 13.4 0.045 13.3 0.7 2.4 3 0 0 3 3 3 0 Retroviral envelope protein PspB PF06667.7 ETS81485.1 - 0.049 13.5 17.2 1.8 8.5 0.5 4.8 3 2 2 5 5 5 0 Phage shock protein B Phycobilisome PF00502.14 ETS81485.1 - 0.053 13.2 1.6 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Phycobilisome protein Colicin PF01024.14 ETS81485.1 - 0.087 12.3 0.2 8 5.9 0.0 2.2 1 1 1 2 2 2 0 Colicin pore forming domain FBA_3 PF08268.7 ETS81485.1 - 0.11 12.1 0.0 5.4 6.7 0.0 2.4 1 1 1 2 2 2 0 F-box associated domain Fzo_mitofusin PF04799.8 ETS81485.1 - 0.14 11.5 15.2 1.4 8.2 5.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region Phage_HK97_TLTM PF06120.6 ETS81485.1 - 0.2 10.9 11.0 0.31 10.3 7.6 1.3 1 1 0 1 1 1 0 Tail length tape measure protein Reo_sigmaC PF04582.7 ETS81485.1 - 0.27 10.3 2.6 16 4.5 0.1 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Lipl32 PF12103.3 ETS81485.1 - 0.28 10.6 1.4 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Exonuc_VII_L PF02601.10 ETS81485.1 - 0.39 9.8 12.5 1.2 8.2 1.8 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit MutS_III PF05192.13 ETS81485.1 - 1.1 8.9 15.7 3.8 7.2 0.1 3.3 1 1 0 2 2 2 0 MutS domain III DUF244 PF03112.9 ETS81485.1 - 1.1 8.7 9.0 0.42 10.1 1.5 2.4 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF DUF1415 PF07209.7 ETS81485.1 - 1.3 8.7 9.2 0.2 11.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) DUF2205 PF10224.4 ETS81485.1 - 2 8.0 20.6 3.4 7.3 0.6 5.0 2 2 4 6 6 6 0 Predicted coiled-coil protein (DUF2205) MitMem_reg PF13012.1 ETS81485.1 - 2 8.4 7.6 1.5 8.9 1.1 2.6 2 2 0 2 2 2 0 Maintenance of mitochondrial structure and function Laminin_II PF06009.7 ETS81485.1 - 2.1 8.1 9.1 2.4 7.9 2.7 2.3 1 1 1 2 2 2 0 Laminin Domain II EMP24_GP25L PF01105.19 ETS81485.1 - 2.3 7.9 12.6 2.7 7.6 0.5 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD GNT-I PF03071.10 ETS81485.1 - 2.3 6.6 10.5 1 7.8 1.1 2.3 2 1 0 2 2 2 0 GNT-I family DUF842 PF05811.8 ETS81485.1 - 2.9 7.3 10.7 22 4.5 1.0 3.4 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF842) FAM196 PF15265.1 ETS81485.1 - 3.2 6.8 8.0 4 6.5 0.1 3.0 1 1 2 3 3 3 0 FAM196 family DASH_Dam1 PF08653.5 ETS81485.1 - 3.5 7.4 14.0 13 5.6 0.2 4.9 3 2 2 5 5 5 0 DASH complex subunit Dam1 SpoIIE PF07228.7 ETS81485.1 - 4.8 6.8 9.6 3.1 7.4 0.5 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF3708 PF12501.3 ETS81485.1 - 5.8 6.7 8.7 14 5.4 0.4 2.7 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter DUF3827 PF12877.2 ETS81487.1 - 0.035 12.2 1.6 0.045 11.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) FUSC PF04632.7 ETS81487.1 - 0.75 8.1 3.1 0.97 7.7 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.17 ETS81488.1 - 0.02 14.8 0.3 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HET PF06985.6 ETS81490.1 - 3.1e-22 79.2 0.0 6.8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFO_IDH_MocA PF01408.17 ETS81491.1 - 3.6e-24 85.5 0.0 6.8e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS81491.1 - 2.7e-07 30.4 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 ETS81491.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 ETS81492.1 - 5.3e-92 308.7 34.8 6.2e-92 308.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81492.1 - 9.1e-35 119.9 31.9 9.1e-35 119.9 22.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRP PF06011.7 ETS81493.1 - 1.1e-20 73.6 22.7 6e-19 67.9 15.7 2.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Amnionless PF14828.1 ETS81493.1 - 0.2 10.1 0.3 6.7 5.0 0.0 2.3 2 0 0 2 2 2 0 Amnionless SGL PF08450.7 ETS81494.1 - 0.00023 20.6 1.1 0.17 11.2 0.7 2.5 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region DUF2279 PF10043.4 ETS81494.1 - 0.023 14.9 0.3 0.045 14.0 0.2 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) Peptidase_M24 PF00557.19 ETS81495.1 - 3.3e-18 66.0 0.0 4.1e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 TraC_F_IV PF11130.3 ETS81496.1 - 0.0028 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer MACPF PF01823.14 ETS81498.1 - 0.025 14.2 0.2 0.067 12.8 0.0 1.7 1 1 1 2 2 2 0 MAC/Perforin domain Jacalin PF01419.12 ETS81500.1 - 8.6e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Reo_sigmaC PF04582.7 ETS81500.1 - 0.03 13.4 11.5 0.17 11.0 8.0 2.1 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Med15 PF09606.5 ETS81500.1 - 0.27 9.3 9.7 0.39 8.8 6.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zn_clus PF00172.13 ETS81501.1 - 6.7e-09 35.5 10.5 6.7e-09 35.5 7.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS81502.1 - 4.5e-33 114.4 27.8 4.5e-33 114.4 19.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81502.1 - 3.3e-13 49.0 6.3 3.3e-13 49.0 4.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter CCSMST1 PF15013.1 ETS81502.1 - 0.18 11.7 1.0 0.57 10.1 0.7 1.8 1 0 0 1 1 1 0 CCSMST1 family DUF3237 PF11578.3 ETS81503.1 - 1.7e-23 82.6 0.0 2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.16 ETS81504.1 - 5.6e-89 299.0 0.0 6.7e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 Amidase HET PF06985.6 ETS81505.1 - 2.7e-19 69.7 0.6 7e-19 68.3 0.4 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 ETS81506.1 - 4.2e-17 62.5 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 ETS81506.1 - 0.00037 19.6 1.1 0.011 14.9 0.5 2.2 1 1 1 2 2 2 1 KaiC AAA_22 PF13401.1 ETS81506.1 - 0.0022 18.1 0.6 0.14 12.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS81506.1 - 0.0023 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS81506.1 - 0.0077 16.2 0.3 0.031 14.2 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 ETS81506.1 - 0.016 14.6 0.1 0.5 9.7 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 ETS81506.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_2 PF07724.9 ETS81506.1 - 0.021 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 ETS81506.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS81506.1 - 0.066 13.5 0.1 0.5 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 ETS81506.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 ETS81506.1 - 0.17 10.9 0.1 0.37 9.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin adh_short_C2 PF13561.1 ETS81507.1 - 3.6e-25 89.1 0.0 5e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS81507.1 - 6.5e-25 87.9 1.2 8.5e-25 87.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81507.1 - 2.6e-08 33.7 0.1 3.6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS81508.1 - 1.6e-25 89.9 0.1 2.5e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81508.1 - 6.5e-23 81.7 0.0 7.8e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS81508.1 - 5.5e-09 35.9 0.1 8.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81508.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 ETS81509.1 - 9.2e-89 298.0 24.3 1.1e-88 297.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81509.1 - 2.1e-24 85.9 45.4 2.7e-17 62.5 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 ETS81510.1 - 2.3e-49 167.7 0.0 2.8e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F_bP_aldolase PF01116.15 ETS81511.1 - 2.2e-78 263.2 0.1 2.5e-78 263.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 ETS81511.1 - 0.048 12.6 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotriesterase family SGL PF08450.7 ETS81512.1 - 1.3e-28 100.0 0.0 3.4e-28 98.6 0.0 1.7 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 ETS81512.1 - 0.0034 17.3 0.0 0.0089 16.0 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 ETS81512.1 - 0.0071 16.3 0.0 0.035 14.1 0.0 2.1 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 ETS81512.1 - 0.073 13.0 0.7 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 NHL repeat adh_short PF00106.20 ETS81513.1 - 1e-27 97.0 4.0 1.3e-27 96.7 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81513.1 - 3e-23 82.8 0.0 3.8e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS81513.1 - 2.6e-12 46.7 1.8 3.7e-12 46.2 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81513.1 - 0.0013 18.2 0.3 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS81513.1 - 0.042 13.8 1.4 0.64 9.9 0.9 2.2 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_6 PF12697.2 ETS81515.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 ETS81516.1 - 4.4e-14 51.8 0.2 7e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81516.1 - 3.8e-08 33.1 15.5 3.8e-08 33.1 10.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 ETS81516.1 - 0.14 11.7 3.5 0.25 10.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF1127 PF06568.6 ETS81516.1 - 5.8 6.4 6.1 0.58 9.6 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) Glyco_hydro_62 PF03664.8 ETS81517.1 - 2.5e-147 489.2 17.4 2.8e-147 489.0 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 FA_desaturase PF00487.19 ETS81518.1 - 9.3e-40 136.6 21.6 1.4e-39 136.1 15.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 ETS81518.1 - 6e-11 41.9 0.0 1.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mem_trans PF03547.13 ETS81518.1 - 0.0045 15.3 0.0 0.0071 14.6 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein FAD_binding_4 PF01565.18 ETS81519.1 - 1.6e-22 79.4 0.4 2.7e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS81519.1 - 0.00033 20.4 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 ETS81519.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Transposase_mut PF00872.13 ETS81519.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family COesterase PF00135.23 ETS81520.1 - 3.4e-66 224.0 0.0 4.5e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS81520.1 - 1.6e-09 37.6 0.3 2.9e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS81520.1 - 0.0074 14.9 0.0 2.8 6.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 ETS81520.1 - 0.15 11.2 0.3 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS81520.1 - 0.23 11.2 1.8 0.49 10.1 1.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 ETS81521.1 - 1e-64 218.5 0.1 1.3e-64 218.2 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS81521.1 - 8.8e-35 120.1 0.1 1.5e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS81521.1 - 8.2e-06 24.9 0.6 0.00064 18.7 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS81521.1 - 2.8e-05 24.0 0.1 8.5e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS81521.1 - 0.00011 21.2 0.2 0.047 12.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 ETS81521.1 - 0.00014 20.5 0.1 0.051 12.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 ETS81521.1 - 0.00014 21.7 0.1 0.098 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS81521.1 - 0.00034 19.6 0.1 0.00069 18.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS81521.1 - 0.0024 17.9 0.2 2 8.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81521.1 - 0.018 14.1 1.2 0.027 13.5 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 ETS81521.1 - 0.049 14.0 0.1 0.35 11.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS81521.1 - 0.09 12.5 0.3 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HET PF06985.6 ETS81522.1 - 4.3e-23 82.0 0.0 7.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 ETS81523.1 - 3.2e-08 33.1 0.0 7.5e-08 31.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain p450 PF00067.17 ETS81524.1 - 1.6e-44 152.2 0.0 2.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1231 PF06802.6 ETS81524.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) Sulfatase PF00884.18 ETS81525.1 - 1.1e-46 159.5 0.0 1.4e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS81525.1 - 0.00017 21.0 0.1 0.035 13.4 0.0 2.7 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 ETS81525.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ADH_zinc_N PF00107.21 ETS81526.1 - 1.1e-25 89.6 0.8 1.7e-25 89.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS81526.1 - 1.5e-11 45.3 0.3 3.1e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS81526.1 - 6e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 ETS81526.1 - 0.0022 17.5 0.3 0.004 16.7 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyoxalase_2 PF12681.2 ETS81526.1 - 0.11 13.1 0.0 23 5.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Abhydrolase_6 PF12697.2 ETS81527.1 - 2.3e-29 102.9 0.0 2.7e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS81527.1 - 1.6e-18 67.0 0.0 1.6e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS81527.1 - 4.8e-11 42.5 0.0 5.3e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS81527.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 ETS81527.1 - 0.0015 17.7 0.0 0.0094 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 ETS81527.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 ETS81527.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) CFEM PF05730.6 ETS81528.1 - 8.7e-14 51.1 11.7 1.3e-13 50.5 8.1 1.3 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.18 ETS81529.1 - 1.2e-16 60.4 4.7 1.2e-16 60.4 3.2 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS81529.1 - 1.1e-11 44.4 1.1 2.4e-11 43.3 0.8 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS81529.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ank_2 PF12796.2 ETS81530.1 - 6.1e-45 151.4 11.0 1.9e-16 60.1 0.0 7.6 6 2 1 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81530.1 - 1.5e-33 112.8 32.7 8.3e-06 25.3 0.0 12.9 13 1 0 13 13 13 8 Ankyrin repeat Ank_3 PF13606.1 ETS81530.1 - 8.8e-29 96.6 13.0 0.0093 16.1 0.0 11.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 ETS81530.1 - 7.7e-21 74.0 12.8 1.1e-05 25.7 0.0 10.0 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81530.1 - 8.1e-21 73.5 26.8 2.3e-05 24.4 0.0 9.1 8 2 2 10 10 10 5 Ankyrin repeats (many copies) NACHT PF05729.7 ETS81530.1 - 7.2e-09 35.5 0.0 4.7e-08 32.8 0.0 2.4 2 1 1 3 3 3 1 NACHT domain AAA_22 PF13401.1 ETS81530.1 - 0.00019 21.6 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS81530.1 - 0.00054 20.0 2.2 0.026 14.4 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS81530.1 - 0.0098 15.3 0.0 0.03 13.8 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS81530.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 ETS81530.1 - 0.085 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 ETS81530.1 - 0.13 12.0 2.2 0.21 11.3 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 BNR PF02012.15 ETS81531.1 - 0.055 13.3 0.2 0.23 11.3 0.2 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Sugar_tr PF00083.19 ETS81532.1 - 4.6e-86 289.1 28.4 5.3e-86 288.9 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81532.1 - 6.3e-12 44.8 42.0 1.5e-10 40.3 23.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 ETS81533.1 - 1.5e-45 155.4 0.0 2.2e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS81533.1 - 3.5e-09 35.9 0.0 9.9e-09 34.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Fungal_trans_2 PF11951.3 ETS81534.1 - 2.9e-21 75.5 2.9 1.5e-20 73.1 2.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81534.1 - 8.1e-09 35.2 10.4 1.5e-08 34.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.1 ETS81534.1 - 3.4 8.4 8.9 3.4 8.4 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1479 PF07350.7 ETS81535.1 - 1.4e-130 435.5 0.0 1.7e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 ETS81535.1 - 0.065 13.2 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 ETS81536.1 - 1.7e-39 135.6 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS81537.1 - 1.2e-65 221.8 0.0 1.6e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS81538.1 - 1.2e-44 152.4 26.5 1.2e-44 152.4 18.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS81538.1 - 0.036 14.0 0.5 0.036 14.0 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1129 PF06570.6 ETS81538.1 - 6.8 5.9 8.1 0.89 8.8 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Fungal_trans_2 PF11951.3 ETS81539.1 - 1.2e-05 24.1 1.1 1.6e-05 23.7 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS81540.1 - 2.7e-38 131.6 22.3 3.4e-38 131.2 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.7 ETS81540.1 - 0.00024 20.7 4.7 0.00046 19.8 0.0 3.4 2 1 2 4 4 4 1 Protein of unknown function, DUF485 Amidohydro_2 PF04909.9 ETS81541.1 - 2e-12 47.2 0.5 6.7e-12 45.5 0.3 1.8 1 1 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 ETS81542.1 - 3.6e-18 65.3 1.1 4.7e-18 64.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS81543.1 - 7.9e-17 60.9 1.1 1.2e-16 60.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.14 ETS81544.1 - 3e-47 160.0 0.0 4.3e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS81544.1 - 1.1e-21 76.6 0.0 1.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS81544.1 - 1.3e-05 25.0 0.0 6.7e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 ETS81544.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 ETS81544.1 - 0.05 14.0 0.1 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SGL PF08450.7 ETS81545.1 - 3.5e-46 157.5 0.0 4.3e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 ETS81545.1 - 1e-12 47.3 0.1 0.058 13.3 0.0 6.3 6 0 0 6 6 6 3 NHL repeat Str_synth PF03088.11 ETS81545.1 - 1.1e-06 28.6 0.0 0.001 19.0 0.0 3.7 2 2 1 3 3 3 1 Strictosidine synthase Arylesterase PF01731.15 ETS81545.1 - 6.3e-06 26.0 0.0 0.0023 17.8 0.0 3.0 2 1 1 3 3 3 1 Arylesterase Lactonase PF10282.4 ETS81545.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBBP PF06739.6 ETS81545.1 - 0.0042 16.8 0.4 5.7 6.8 0.1 3.5 3 0 0 3 3 3 2 Beta-propeller repeat Sugar_tr PF00083.19 ETS81546.1 - 2e-93 313.4 16.7 2.3e-93 313.2 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81546.1 - 5.9e-23 81.1 9.5 5.9e-23 81.1 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 ETS81548.1 - 1.4e-21 77.1 5.4 5.8e-19 68.6 3.7 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS81548.1 - 7.9e-19 67.9 0.0 1.8e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 ETS81548.1 - 1.1e-06 28.2 0.0 2.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat KAP_NTPase PF07693.9 ETS81548.1 - 0.0072 15.3 0.2 0.18 10.7 0.0 2.2 1 1 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.1 ETS81548.1 - 0.012 15.5 0.1 0.038 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETS81548.1 - 0.014 15.5 0.0 0.058 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 ETS81549.1 - 7.6e-84 281.8 27.2 8.6e-84 281.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81549.1 - 7.4e-25 87.3 47.1 1.9e-22 79.4 17.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS81549.1 - 0.00026 19.3 2.2 0.00026 19.3 1.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F_bP_aldolase PF01116.15 ETS81550.1 - 7.4e-81 271.3 0.0 8.5e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.16 ETS81551.1 - 1.9e-18 66.7 0.0 2.6e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS81551.1 - 4.7e-12 45.1 0.0 6.3e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS81551.1 - 2.6e-08 33.0 0.1 6e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETS81551.1 - 2.4e-07 29.9 0.0 7.6e-05 21.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS81551.1 - 1.8e-06 27.9 0.2 9.2e-05 22.4 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS81551.1 - 3.4e-06 27.1 0.1 8.8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 ETS81551.1 - 0.00022 20.9 0.2 0.0023 17.6 0.0 2.5 2 1 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 ETS81551.1 - 0.00046 20.0 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETS81551.1 - 0.0081 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 ETS81551.1 - 0.026 14.4 0.1 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PhyH PF05721.8 ETS81552.1 - 3.6e-12 46.7 0.2 7.4e-12 45.7 0.2 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS81552.1 - 1.1e-06 27.4 0.0 0.052 12.0 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.1 ETS81552.1 - 0.04 14.4 0.1 0.7 10.4 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 ETS81553.1 - 3.9e-10 39.0 1.1 5.5e-10 38.5 0.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.14 ETS81554.1 - 2.9e-52 176.3 0.0 3.8e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS81554.1 - 6.3e-18 64.5 0.0 7.4e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 ETS81554.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 ETS81554.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lactamase_B_2 PF12706.2 ETS81556.1 - 4.3e-20 72.0 0.0 5.4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS81556.1 - 1.4e-08 34.6 0.2 2.5e-08 33.7 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.17 ETS81557.1 - 4.2e-67 226.6 0.0 5.5e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 ETS81558.1 - 4.1e-08 32.9 4.1 4.1e-08 32.9 2.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 ETS81559.1 - 3e-77 259.5 0.0 5.8e-77 258.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS81559.1 - 1.1e-44 153.0 0.0 1.9e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 ETS81559.1 - 6.3e-30 103.4 0.4 1.5e-29 102.2 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 ETS81559.1 - 9.5e-23 80.4 0.0 2.5e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 ETS81559.1 - 1.5e-22 79.6 7.1 2.5e-11 43.6 0.7 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS81559.1 - 2.3e-06 26.8 0.0 6.9e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 ETS81559.1 - 0.00028 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_5 PF12695.2 ETS81559.1 - 0.001 18.8 0.1 0.16 11.7 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family adh_short PF00106.20 ETS81559.1 - 0.0013 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase HTH_35 PF13693.1 ETS81559.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Polysacc_synt_2 PF02719.10 ETS81559.1 - 0.1 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 ETS81560.1 - 2.4e-11 43.3 0.0 4.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS81560.1 - 1.9e-09 37.2 0.1 1e-08 34.8 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS81560.1 - 0.0021 18.9 0.1 0.0041 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS81560.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Semialdhyde_dh PF01118.19 ETS81560.1 - 0.023 14.9 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS81560.1 - 0.029 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Aldo_ket_red PF00248.16 ETS81561.1 - 7.6e-52 175.8 0.0 8.7e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_F PF01990.12 ETS81561.1 - 0.058 13.7 0.0 49 4.3 0.0 3.2 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit FAD_binding_4 PF01565.18 ETS81562.1 - 1.4e-23 82.9 0.5 8e-23 80.4 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS81562.1 - 2.8e-06 27.1 0.4 7.7e-06 25.7 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.14 ETS81563.1 - 1.3e-64 218.1 0.1 2e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS81563.1 - 3.2e-30 105.3 0.0 6.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS81563.1 - 3.3e-05 22.9 1.9 0.00012 21.0 1.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS81563.1 - 3.7e-05 22.7 0.1 0.03 13.1 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 ETS81563.1 - 5.1e-05 22.3 0.0 8.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS81563.1 - 9.6e-05 22.3 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS81563.1 - 0.00088 19.3 0.0 0.2 11.6 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS81563.1 - 0.0028 17.5 0.0 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81563.1 - 0.0052 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS81563.1 - 0.0077 16.0 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS81563.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS81563.1 - 0.016 13.7 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 ETS81563.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aconitase PF00330.15 ETS81564.1 - 2.1e-155 517.7 0.0 8.1e-155 515.8 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS81564.1 - 3.5e-38 130.6 0.0 6.7e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1749 PF08538.5 ETS81565.1 - 0.03 13.2 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Actin PF00022.14 ETS81566.1 - 2.2e-131 437.9 0.0 2.5e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Actin COesterase PF00135.23 ETS81567.1 - 3.9e-66 223.8 3.7 8.6e-66 222.7 2.5 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS81567.1 - 4.4e-05 23.1 1.0 0.00016 21.3 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF3602 PF12223.3 ETS81568.1 - 1e-08 35.4 8.3 0.0033 17.7 0.8 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) ADH_zinc_N_2 PF13602.1 ETS81569.1 - 3e-21 76.6 0.0 5.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS81569.1 - 2.7e-14 52.8 0.1 5.1e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS81569.1 - 4.4e-09 36.0 0.9 5.1e-07 29.4 0.0 3.3 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_28 PF00295.12 ETS81570.1 - 1.7e-31 109.4 3.9 2.3e-31 108.9 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pentapeptide_4 PF13599.1 ETS81570.1 - 0.19 11.5 2.4 66 3.4 0.0 3.8 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Cu-oxidase_3 PF07732.10 ETS81571.1 - 1.6e-46 156.8 5.8 8.7e-46 154.4 0.2 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS81571.1 - 5.3e-44 149.0 9.9 6.5e-38 129.3 0.6 4.3 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 ETS81571.1 - 1.3e-33 116.1 0.1 3.5e-33 114.7 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Peptidase_A4 PF01828.12 ETS81572.1 - 2.6e-53 180.2 13.2 3.7e-53 179.6 9.1 1.2 1 0 0 1 1 1 1 Peptidase A4 family IL13 PF03487.8 ETS81572.1 - 0.055 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Interleukin-13 Methyltransf_23 PF13489.1 ETS81573.1 - 7.3e-13 48.5 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81573.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81573.1 - 1.6e-07 31.8 0.0 3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81573.1 - 2.1e-07 31.3 0.0 5.1e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81573.1 - 3e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS81573.1 - 3.4e-06 27.0 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 ETS81573.1 - 0.0064 15.9 0.0 0.0086 15.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 ETS81573.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 ETS81573.1 - 0.019 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 ETS81573.1 - 0.058 13.0 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_21 PF05050.7 ETS81573.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_25 PF13649.1 ETS81573.1 - 0.077 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_16 PF13191.1 ETS81574.1 - 3.6e-08 33.5 0.2 6e-07 29.6 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS81574.1 - 1.8e-07 31.3 2.2 7.2e-06 26.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.1 ETS81574.1 - 4.3e-05 22.9 7.1 2 8.4 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat NACHT PF05729.7 ETS81574.1 - 0.00029 20.5 0.0 0.0011 18.6 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.1 ETS81574.1 - 0.013 15.8 12.0 1 9.7 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_17 PF13207.1 ETS81574.1 - 0.018 15.8 0.0 0.069 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 ETS81574.1 - 0.018 14.9 23.2 4.2 7.3 0.0 9.8 9 2 2 11 11 11 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS81574.1 - 0.033 14.1 10.4 12 5.9 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_19 PF13245.1 ETS81574.1 - 0.034 13.9 0.0 0.14 11.9 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Turandot PF07240.6 ETS81574.1 - 0.077 12.5 1.2 2.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot FUSC PF04632.7 ETS81576.1 - 0.068 11.5 2.0 0.13 10.6 1.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family EF-1_beta_acid PF10587.4 ETS81576.1 - 2.8 8.1 6.1 0.34 11.1 0.6 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Glyco_hydro_39 PF01229.12 ETS81577.1 - 6.9e-05 21.4 0.5 0.0001 20.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_31 PF01055.21 ETS81578.1 - 2.5e-130 435.2 3.2 2.9e-130 435.0 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS81578.1 - 0.00014 21.6 1.5 0.00065 19.5 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like DUF2188 PF09954.4 ETS81578.1 - 0.024 14.5 0.0 5.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Sugar_tr PF00083.19 ETS81579.1 - 3.6e-79 266.4 26.5 4.4e-79 266.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81579.1 - 2.6e-20 72.4 29.5 2.6e-20 72.4 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2417 PF10329.4 ETS81579.1 - 0.037 13.4 0.3 0.37 10.1 0.0 2.5 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Fungal_trans PF04082.13 ETS81580.1 - 1.9e-14 53.2 3.9 3.4e-14 52.3 2.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 ETS81581.1 - 4.4e-56 190.3 0.6 5.8e-56 189.9 0.4 1.1 1 0 0 1 1 1 1 Sulfatase ALAD PF00490.16 ETS81582.1 - 3e-118 394.3 0.0 3.6e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase WD40 PF00400.27 ETS81583.1 - 9.4e-35 117.2 0.1 8.1e-10 38.2 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat Gmad1 PF10647.4 ETS81583.1 - 0.0014 18.0 0.2 0.0084 15.5 0.1 1.9 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 ETS81583.1 - 0.002 17.8 0.0 0.65 9.6 0.0 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A SdiA-regulated PF06977.6 ETS81583.1 - 0.023 13.6 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated Nucleoporin_N PF08801.6 ETS81583.1 - 0.064 11.9 0.0 1.8 7.2 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETS81583.1 - 0.15 10.1 0.0 0.2 9.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FTHFS PF01268.14 ETS81585.1 - 2.5e-257 854.3 0.4 3.4e-257 853.9 0.3 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 ETS81585.1 - 3.8e-68 227.6 1.1 3.8e-68 227.6 0.8 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 ETS81585.1 - 1.2e-37 128.5 0.4 2.9e-37 127.2 0.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF1510 PF07423.6 ETS81587.1 - 9.2e-06 25.1 13.2 1.2e-05 24.8 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 ETS81587.1 - 0.0013 16.5 0.5 0.0015 16.3 0.3 1.0 1 0 0 1 1 1 1 Ycf1 VID27 PF08553.5 ETS81587.1 - 0.0027 16.0 14.3 0.0028 15.9 9.9 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Zip PF02535.17 ETS81587.1 - 0.018 14.0 0.2 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Adipogenin PF15202.1 ETS81587.1 - 0.033 14.0 0.5 0.033 14.0 0.3 1.8 2 0 0 2 2 2 0 Adipogenin DDHD PF02862.12 ETS81587.1 - 0.052 13.3 0.4 0.059 13.1 0.3 1.2 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.1 ETS81587.1 - 0.26 9.4 1.7 0.42 8.7 1.2 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Nop14 PF04147.7 ETS81587.1 - 0.42 8.4 48.9 0.51 8.2 33.9 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 ETS81587.1 - 0.52 9.7 10.5 0.56 9.6 7.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Glypican PF01153.14 ETS81587.1 - 0.58 8.6 6.9 0.67 8.4 4.7 1.1 1 0 0 1 1 1 0 Glypican Mpp10 PF04006.7 ETS81587.1 - 0.76 8.0 35.0 0.84 7.9 24.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Paf1 PF03985.8 ETS81587.1 - 1.3 7.6 26.7 1.6 7.3 18.5 1.2 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.5 ETS81587.1 - 3 7.8 16.1 3.9 7.4 11.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Trypan_PARP PF05887.6 ETS81587.1 - 3.9 7.2 24.5 4.9 6.9 17.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_polI_A34 PF08208.6 ETS81587.1 - 4.6 6.8 11.3 5.6 6.5 7.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.3 ETS81587.1 - 6.2 5.3 10.4 7.7 4.9 7.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Usp PF00582.21 ETS81587.1 - 9.4 6.4 7.4 13 6.0 5.1 1.2 1 0 0 1 1 1 0 Universal stress protein family Fork_head PF00250.13 ETS81588.1 - 6e-13 48.6 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 ETS81588.1 - 0.00062 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Voltage_CLC PF00654.15 ETS81589.1 - 0.0024 16.9 4.4 0.0031 16.6 3.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel Sulfate_transp PF00916.15 ETS81590.1 - 0.00026 20.0 11.2 0.00026 20.0 7.8 3.0 1 1 1 2 2 2 1 Sulfate transporter family p450 PF00067.17 ETS81591.1 - 9.4e-48 162.8 0.0 2.7e-47 161.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 PhoU PF01895.14 ETS81591.1 - 0.064 13.7 0.8 0.18 12.2 0.5 1.7 1 0 0 1 1 1 0 PhoU domain DNA_pol3_a_NII PF11490.3 ETS81591.1 - 0.081 12.5 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF3405 PF11885.3 ETS81593.1 - 9.4e-187 621.1 0.2 9.4e-187 621.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DUF1510 PF07423.6 ETS81593.1 - 1.4e-05 24.5 4.8 2.5e-05 23.7 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MRP-S27 PF10037.4 ETS81593.1 - 0.018 13.9 0.6 0.028 13.3 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Neur_chan_memb PF02932.11 ETS81593.1 - 0.22 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 ETS81593.1 - 2.2 6.2 9.6 3.1 5.7 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 ETS81594.1 - 3.7e-44 150.8 35.5 3.7e-44 150.8 24.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_L44 PF00935.14 ETS81595.1 - 9.4e-35 118.4 11.1 1.5e-34 117.8 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DNA_methylase PF00145.12 ETS81597.1 - 2.1e-16 60.0 0.1 1.1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase SNF2_N PF00176.18 ETS81598.1 - 1.3e-20 73.3 0.0 3.4e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain SpoA PF01052.15 ETS81598.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.9 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Ureidogly_hydro PF04115.7 ETS81599.1 - 2.8e-46 156.8 0.0 3.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF3592 PF12158.3 ETS81600.1 - 1 9.1 3.8 1.8 8.3 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Aromatic_hydrox PF11723.3 ETS81601.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase GAS PF13851.1 ETS81602.1 - 0.0009 18.4 7.6 0.0014 17.8 5.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 ETS81602.1 - 0.0056 16.4 1.7 0.0072 16.1 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Rootletin PF15035.1 ETS81602.1 - 0.0086 16.0 3.0 0.013 15.5 2.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.3 ETS81602.1 - 0.034 13.9 1.8 0.09 12.5 1.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PilJ PF13675.1 ETS81602.1 - 0.036 14.3 1.4 0.51 10.6 0.8 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_2 PF07716.10 ETS81602.1 - 0.061 13.1 0.6 0.061 13.1 0.4 2.9 2 1 1 3 3 3 0 Basic region leucine zipper TPR_MLP1_2 PF07926.7 ETS81602.1 - 0.13 11.9 5.0 0.27 10.9 3.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2630 PF10944.3 ETS81602.1 - 0.15 12.2 5.4 0.14 12.2 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) bZIP_1 PF00170.16 ETS81602.1 - 0.17 11.8 7.2 0.27 11.2 1.0 3.0 2 1 0 3 3 3 0 bZIP transcription factor DUF3552 PF12072.3 ETS81602.1 - 0.2 10.8 10.5 0.62 9.2 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 ETS81602.1 - 0.27 10.1 5.0 0.47 9.3 3.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 ETS81602.1 - 0.37 10.3 4.8 0.58 9.6 3.4 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 ETS81602.1 - 1.9 6.2 5.8 2.7 5.7 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1281 PF06924.6 ETS81603.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) MFS_1 PF07690.11 ETS81604.1 - 7.1e-09 34.8 39.5 9.6e-07 27.8 13.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2566 PF10753.4 ETS81604.1 - 0.99 9.3 10.6 0.39 10.6 1.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2566) Sugar_tr PF00083.19 ETS81605.1 - 4.2e-121 404.6 27.0 4.8e-121 404.4 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81605.1 - 2.4e-20 72.5 39.8 1.6e-14 53.4 10.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS81605.1 - 3.1e-07 29.1 30.1 9.8e-07 27.5 6.3 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein YrhC PF14143.1 ETS81605.1 - 1.1 9.2 3.8 3.6 7.6 0.2 3.0 2 0 0 2 2 2 0 YrhC-like protein Fungal_trans_2 PF11951.3 ETS81606.1 - 2.3e-09 36.3 2.3 4.9e-09 35.2 1.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 ETS81606.1 - 0.0019 18.0 0.2 0.005 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 ETS81606.1 - 0.14 11.3 0.1 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR Patatin PF01734.17 ETS81607.1 - 1.2e-27 97.2 0.1 2.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Sugar_tr PF00083.19 ETS81608.1 - 2.1e-108 362.8 21.8 2.5e-108 362.5 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81608.1 - 2.6e-23 82.2 51.1 8.6e-23 80.6 17.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 ETS81609.1 - 1.2e-09 37.8 11.7 0.038 14.3 0.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS81609.1 - 0.00055 20.1 13.7 0.45 10.9 0.4 4.3 3 1 0 3 3 3 3 Zinc finger, C2H2 type Peptidase_C14 PF00656.17 ETS81609.1 - 0.0035 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Caspase domain zf-C2H2_jaz PF12171.3 ETS81609.1 - 0.21 11.7 1.8 15 5.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 ETS81609.1 - 5.5 7.4 8.9 63 4.0 0.2 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Glyco_hydro_43 PF04616.9 ETS81610.1 - 1.1e-18 67.3 5.8 1.9e-18 66.5 4.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_31 PF01055.21 ETS81611.1 - 5.9e-169 562.5 4.0 7.4e-169 562.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS81611.1 - 1.4e-10 40.8 1.2 9.3e-10 38.2 0.4 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.19 ETS81612.1 - 2.8e-106 355.7 33.4 3.2e-106 355.5 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81612.1 - 5.6e-24 84.5 31.0 5.6e-24 84.5 21.5 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 ETS81613.1 - 3e-16 59.0 25.8 5e-10 39.1 5.0 3.3 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS81613.1 - 5.1e-16 58.3 0.3 9.3e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 ETS81615.1 - 2.1e-76 257.0 0.0 2.5e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS81615.1 - 0.02 14.2 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 ETS81615.1 - 0.094 11.1 0.0 0.17 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DEAD PF00270.24 ETS81616.1 - 9.1e-46 155.4 0.2 5.9e-44 149.5 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS81616.1 - 5.4e-22 77.4 0.3 2.9e-21 75.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS81616.1 - 9.2e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 ETS81616.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Pec_lyase_C PF00544.14 ETS81617.1 - 4.5e-21 75.2 3.4 8.3e-21 74.3 2.4 1.5 1 0 0 1 1 1 1 Pectate lyase PPR_3 PF13812.1 ETS81618.1 - 4.2e-11 42.2 1.5 0.079 13.2 0.0 8.5 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 ETS81618.1 - 6.6e-11 42.0 0.1 0.17 11.8 0.0 6.6 5 1 1 6 6 6 4 PPR repeat family PPR PF01535.15 ETS81618.1 - 2.2e-06 27.2 3.2 4.8 7.3 0.0 7.4 9 0 0 9 9 9 2 PPR repeat Clathrin PF00637.15 ETS81618.1 - 0.03 13.9 0.1 1.7 8.2 0.0 3.6 4 0 0 4 4 4 0 Region in Clathrin and VPS Ribosomal_S18 PF01084.15 ETS81619.1 - 8.6e-12 44.7 0.1 1.9e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 Ribosomal_S4 PF00163.14 ETS81620.1 - 5.7e-14 52.2 0.7 1.1e-13 51.3 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETS81620.1 - 1.2e-12 47.0 0.0 2.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain THDPS_N_2 PF14805.1 ETS81620.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SNF2_N PF00176.18 ETS81621.1 - 1.8e-53 181.3 0.1 2.4e-53 180.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 ETS81621.1 - 4e-23 81.0 1.3 1.1e-22 79.6 0.9 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 ETS81621.1 - 1.8e-15 56.5 0.0 1.5e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS81621.1 - 9.8e-05 22.2 0.0 0.0045 16.8 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS81621.1 - 0.0029 17.1 0.0 0.0073 15.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.2 ETS81622.1 - 2.6e-06 27.6 0.0 0.0025 18.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS81622.1 - 0.00064 20.1 0.0 1.6 9.3 0.0 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS81622.1 - 0.0029 17.3 0.1 0.85 9.5 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 ETS81622.1 - 0.0094 16.1 0.1 0.41 11.0 0.0 3.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETS81622.1 - 0.052 13.8 0.0 7.7 6.9 0.0 4.2 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Reo_sigmaC PF04582.7 ETS81622.1 - 0.73 8.9 13.8 0.32 10.1 2.3 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 ETS81622.1 - 0.73 9.6 20.2 35 4.1 0.2 4.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AA_permease_2 PF13520.1 ETS81623.1 - 8.8e-59 199.1 33.5 1.1e-58 198.8 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS81623.1 - 1.5e-23 82.8 34.2 1.5e-21 76.3 17.7 2.2 2 0 0 2 2 2 2 Amino acid permease DUF1676 PF07898.8 ETS81624.1 - 0.036 14.3 0.1 0.041 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Aromatic_hydrox PF11723.3 ETS81624.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase Secretin_N_2 PF07655.8 ETS81624.1 - 9.4 6.7 10.7 3.4 8.1 3.8 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain Abhydrolase_3 PF07859.8 ETS81625.1 - 1.2e-39 136.1 0.0 1.4e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS81625.1 - 2.1e-09 37.5 0.1 3.2e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81625.1 - 3.9e-09 36.4 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS81625.1 - 9.3e-08 31.6 0.0 0.0007 18.9 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 ETS81625.1 - 2.4e-06 26.9 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.3 ETS81625.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 ETS81625.1 - 0.0034 16.9 0.0 0.053 13.0 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS81625.1 - 0.0035 17.5 0.0 0.0066 16.7 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 ETS81625.1 - 0.01 15.2 0.0 0.07 12.5 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 ETS81625.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 ETS81625.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 ETS81625.1 - 0.13 10.7 0.0 0.73 8.2 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) But2 PF09792.4 ETS81626.1 - 0.12 12.1 0.0 0.5 10.1 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Kinesin PF00225.18 ETS81627.1 - 4.8e-110 367.3 1.4 7.4e-110 366.7 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain DUF3694 PF12473.3 ETS81627.1 - 8.7e-44 148.5 0.0 1.9e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 ETS81627.1 - 1.8e-06 27.8 1.4 1.8e-06 27.8 1.0 2.4 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 ETS81627.1 - 2.5e-05 24.2 0.0 0.0002 21.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain PH PF00169.24 ETS81627.1 - 0.0015 18.6 0.0 0.0046 17.1 0.0 1.9 1 0 0 1 1 1 1 PH domain p450 PF00067.17 ETS81628.1 - 5.6e-53 180.1 0.0 6.8e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 ETS81629.1 - 4.4e-06 25.9 0.5 9.1e-06 24.8 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NAD_binding_1 PF00175.16 ETS81630.1 - 4.3e-25 88.4 0.0 7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 ETS81630.1 - 3.3e-15 55.9 0.0 5.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 ETS81630.1 - 0.00025 20.9 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 ETS81630.1 - 0.022 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Peptidase_C48 PF02902.14 ETS81631.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF1279 PF06916.8 ETS81632.1 - 1.9e-28 98.6 0.0 3.9e-28 97.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3619 PF12279.3 ETS81632.1 - 0.91 9.6 3.9 1.9 8.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DUF3390 PF11870.3 ETS81633.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Lipase_GDSL PF00657.17 ETS81634.1 - 1.5e-13 51.1 3.3 2.3e-13 50.5 2.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS81634.1 - 3.3e-13 50.1 0.5 4.7e-13 49.6 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 ETS81634.1 - 0.00084 19.1 0.1 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Sedlin_N PF04628.8 ETS81635.1 - 5.3e-18 65.1 0.0 6.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 ETS81635.1 - 0.16 11.6 0.0 4.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Acyl_transf_1 PF00698.16 ETS81636.1 - 2.8e-22 79.4 1.1 4.8e-15 55.6 0.1 2.1 2 0 0 2 2 2 2 Acyl transferase domain Adap_comp_sub PF00928.16 ETS81637.1 - 5.1e-60 202.7 0.0 8.3e-60 202.0 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 ETS81637.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mpp10 PF04006.7 ETS81638.1 - 4.8e-95 319.1 65.2 8.5e-94 315.0 45.2 2.0 1 1 0 1 1 1 1 Mpp10 protein DUF4536 PF15055.1 ETS81639.1 - 5.9e-05 23.0 0.6 5.9e-05 23.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) Pkinase PF00069.20 ETS81641.1 - 5.2e-56 189.6 0.0 7.5e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81641.1 - 7e-19 67.9 0.3 1.2e-18 67.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 ETS81641.1 - 0.017 14.6 1.1 0.036 13.6 0.8 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 ETS81641.1 - 0.024 14.3 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 ETS81641.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Cytochrom_B561 PF03188.11 ETS81642.1 - 5e-10 39.3 11.1 5e-10 39.3 7.7 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 ETS81642.1 - 4e-05 23.1 2.8 4e-05 23.1 1.9 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4191 PF13829.1 ETS81642.1 - 0.051 12.6 0.4 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) ISK_Channel PF02060.10 ETS81642.1 - 0.44 10.1 1.7 2 7.9 0.0 2.4 2 1 0 2 2 2 0 Slow voltage-gated potassium channel Cytochrom_B_N PF00033.14 ETS81642.1 - 1.3 8.3 15.6 52 3.1 11.0 3.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 ETS81642.1 - 4.1 6.7 12.6 21 4.4 8.9 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2306 PF10067.4 ETS81642.1 - 4.8 7.3 9.1 0.17 12.0 0.7 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Amidase PF01425.16 ETS81644.1 - 5.7e-91 305.5 0.0 6.7e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Amidase p450 PF00067.17 ETS81645.1 - 1.2e-55 188.9 0.0 1.5e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 ETS81646.1 - 2.1e-47 161.4 3.0 1.5e-46 158.6 2.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS81646.1 - 4.4e-08 33.2 0.1 8.3e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS81646.1 - 3.5e-05 23.1 0.0 0.074 12.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 ETS81646.1 - 0.00075 18.3 0.0 0.0068 15.1 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS81646.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS81646.1 - 0.026 13.8 0.2 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 ETS81646.1 - 0.042 13.2 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ank_2 PF12796.2 ETS81647.1 - 8.9e-16 58.0 0.0 5e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS81647.1 - 4.9e-14 52.0 1.0 2.3e-07 30.8 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS81647.1 - 5.7e-14 52.1 0.4 6.9e-07 29.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 ETS81647.1 - 2e-13 49.4 1.3 7.9e-07 28.5 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeat NACHT PF05729.7 ETS81647.1 - 8.2e-11 41.8 0.0 2.3e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Ank_3 PF13606.1 ETS81647.1 - 1.7e-10 40.0 0.1 0.0024 17.9 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.1 ETS81647.1 - 7.7e-05 22.7 0.1 0.00064 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 ETS81647.1 - 0.00021 21.2 0.1 0.001 19.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 ETS81647.1 - 0.00035 20.7 0.3 0.0047 17.0 0.0 2.8 2 1 1 3 3 2 1 AAA domain PGAP1 PF07819.8 ETS81647.1 - 0.0009 18.8 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 ETS81647.1 - 0.002 17.4 0.0 0.074 12.3 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_30 PF13604.1 ETS81647.1 - 0.027 14.0 0.1 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 ETS81647.1 - 0.039 12.7 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_33 PF13671.1 ETS81647.1 - 0.048 13.5 0.1 0.98 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETS81647.1 - 0.05 13.1 0.6 0.52 9.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 ETS81647.1 - 0.06 13.5 0.4 0.18 12.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_10 PF12846.2 ETS81647.1 - 0.073 12.4 0.2 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 ETS81647.1 - 0.09 12.4 0.0 0.34 10.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 ETS81647.1 - 0.36 9.7 3.0 1.9 7.4 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain MARVEL PF01284.18 ETS81648.1 - 1.2e-26 93.3 18.7 1.4e-26 93.0 13.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain EVI2A PF05399.6 ETS81648.1 - 0.024 13.8 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MpPF26 PF07666.6 ETS81648.1 - 1.9 8.4 10.7 7.8 6.4 5.5 2.7 2 1 0 2 2 2 0 M penetrans paralogue family 26 COQ7 PF03232.8 ETS81649.1 - 1.7e-66 222.9 0.1 2.1e-66 222.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 ETS81649.1 - 0.00071 19.8 0.0 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin DUF724 PF05266.9 ETS81649.1 - 0.067 12.8 0.5 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Plus-3 PF03126.13 ETS81650.1 - 1.3e-30 105.5 0.0 2.6e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain YebO PF13974.1 ETS81650.1 - 0.33 10.7 2.7 1.5 8.6 1.8 2.1 1 0 0 1 1 1 0 YebO-like protein Fungal_trans PF04082.13 ETS81652.1 - 1.4e-09 37.2 1.8 5.2e-08 32.0 1.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 ETS81653.1 - 2.1e-20 73.3 0.0 3.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_2 PF04909.9 ETS81654.1 - 8e-24 84.6 7.2 1.4e-23 83.8 5.0 1.7 1 1 0 1 1 1 1 Amidohydrolase IDO PF01231.13 ETS81655.1 - 2.2e-37 128.5 0.0 3e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase But2 PF09792.4 ETS81656.1 - 1.5e-06 28.0 0.4 3.8e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Daxx PF03344.10 ETS81656.1 - 0.00056 18.5 13.9 0.00074 18.1 9.6 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 ETS81656.1 - 0.022 12.7 11.4 0.028 12.3 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 ETS81656.1 - 0.058 12.6 9.0 0.076 12.2 6.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 ETS81656.1 - 0.45 9.7 11.5 0.59 9.3 7.9 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 ETS81656.1 - 0.73 8.4 14.2 1 8.0 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 ETS81656.1 - 1.9 7.5 13.6 2.4 7.1 9.4 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 ETS81656.1 - 9.1 5.8 11.8 13 5.2 8.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region OB_NTP_bind PF07717.11 ETS81657.1 - 2.1e-29 101.6 0.0 6.5e-29 100.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS81657.1 - 1.4e-24 86.0 0.1 1.4e-24 86.0 0.1 3.6 4 1 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS81657.1 - 1.6e-12 47.0 0.0 4.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS81657.1 - 7.1e-06 25.6 0.0 2.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS81657.1 - 1e-05 25.7 0.1 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS81657.1 - 0.00033 19.6 0.0 0.00076 18.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 ETS81657.1 - 0.035 14.4 1.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 ETS81657.1 - 0.045 13.4 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 ETS81657.1 - 0.057 13.3 3.2 0.66 9.8 0.1 3.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 ETS81657.1 - 0.074 12.4 0.2 0.17 11.3 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 ETS81657.1 - 0.15 12.3 0.1 0.15 12.3 0.0 3.0 1 1 0 2 2 1 0 AAA domain DnaJ PF00226.26 ETS81658.1 - 4.4e-24 83.9 1.1 4.4e-24 83.9 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETS81658.1 - 2.2e-13 50.0 17.7 3.6e-13 49.3 12.2 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 ETS81658.1 - 3.3e-09 36.5 0.0 2.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 ETS81658.1 - 0.00058 19.5 6.8 0.063 12.9 0.4 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 ETS81658.1 - 0.4 10.5 12.0 3.9 7.3 0.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_23 PF13489.1 ETS81659.1 - 7.4e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81659.1 - 4.3e-07 30.3 0.0 8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81659.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81659.1 - 3.6e-05 24.1 0.0 6.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81659.1 - 0.0019 18.7 0.0 0.0037 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS81659.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS81659.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 ETS81660.1 - 2.6e-06 27.4 2.3 0.00011 22.1 0.7 3.2 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS81660.1 - 0.0014 18.3 0.0 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS81660.1 - 0.0023 17.9 0.2 0.0077 16.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS81660.1 - 0.0032 16.4 0.9 0.015 14.2 0.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS81660.1 - 0.004 17.2 0.2 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS81660.1 - 0.018 13.6 1.4 0.024 13.2 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS81660.1 - 0.019 13.9 0.1 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.10 ETS81660.1 - 0.075 12.5 0.9 0.13 11.8 0.6 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Mito_fiss_Elm1 PF06258.6 ETS81660.1 - 0.095 11.6 0.2 0.23 10.3 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Thi4 PF01946.12 ETS81660.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SPX PF03105.14 ETS81661.1 - 1.4e-18 67.6 4.6 1e-09 38.6 0.0 3.0 2 1 1 3 3 3 2 SPX domain RhgB_N PF09284.5 ETS81662.1 - 1.2e-84 283.6 12.3 1.2e-84 283.6 8.5 1.6 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 ETS81662.1 - 8.2e-48 162.1 0.0 8.2e-48 162.1 0.0 2.5 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 ETS81662.1 - 9.2e-15 54.5 2.5 4.3e-14 52.3 1.7 2.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 ETS81662.1 - 0.0015 18.5 1.2 0.0015 18.5 0.8 3.4 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Glyco_hydro_10 PF00331.15 ETS81664.1 - 2.4e-86 289.6 0.0 2.7e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-MYND PF01753.13 ETS81665.1 - 9.1e-11 41.4 17.8 1.6e-10 40.6 12.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 ETS81665.1 - 1.6 8.6 7.8 4.2 7.3 5.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 JTB PF05439.7 ETS81665.1 - 2.1 8.1 6.8 3.1 7.5 4.7 1.2 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) UDPGT PF00201.13 ETS81666.1 - 4.8e-11 41.8 0.1 1.2e-10 40.6 0.2 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS81666.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Lipase_GDSL PF00657.17 ETS81667.1 - 3.8e-17 62.8 0.7 5.1e-17 62.4 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.13 ETS81668.1 - 4.5e-11 42.1 0.4 8.7e-11 41.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS81669.1 - 8.9e-14 51.7 0.9 2e-13 50.6 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81669.1 - 6.4e-07 29.2 0.6 1.5e-06 27.9 0.4 1.6 1 0 0 1 1 1 1 KR domain DUF2647 PF10839.3 ETS81670.1 - 0.028 14.4 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) Phage-MuB_C PF09077.6 ETS81671.1 - 0.16 11.6 3.5 0.11 12.2 0.4 2.2 2 1 0 2 2 2 0 Mu B transposition protein, C terminal LOH1CR12 PF10158.4 ETS81671.1 - 0.91 9.3 7.0 1.6 8.5 0.1 2.7 2 1 1 3 3 3 0 Tumour suppressor protein WD40 PF00400.27 ETS81672.1 - 2.3e-28 97.0 10.6 2.3e-09 36.7 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat SGL PF08450.7 ETS81672.1 - 0.0029 17.0 0.0 0.031 13.6 0.0 2.5 1 1 3 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region PFU PF09070.6 ETS81673.1 - 3.5e-42 143.0 0.2 8e-42 141.9 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 ETS81673.1 - 4.1e-38 127.9 12.6 8.4e-08 31.8 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat PUL PF08324.6 ETS81673.1 - 4.4e-38 130.6 0.0 7.2e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 ETS81673.1 - 0.018 14.7 0.0 1.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SRR1 PF07985.7 ETS81675.1 - 7.9e-10 38.5 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 PhyH PF05721.8 ETS81676.1 - 2e-07 31.2 0.0 5.5e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS81676.1 - 1.2e-06 27.2 0.0 0.0066 14.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 ETS81676.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase VWA_3 PF13768.1 ETS81677.1 - 1.2e-28 99.7 0.0 2.7e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 ETS81677.1 - 2.7e-22 78.6 0.0 7.8e-22 77.1 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 ETS81677.1 - 7.2e-10 39.2 0.2 5.6e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 ETS81677.1 - 3.5e-07 29.5 0.0 8.3e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 ETS81677.1 - 5.3e-07 29.5 0.0 9.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 ETS81677.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 ETS81677.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 vWA found in TerF C terminus Glyco_hydro_92 PF07971.7 ETS81678.1 - 2.7e-169 564.0 0.4 3.4e-169 563.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 p450 PF00067.17 ETS81680.1 - 1.7e-40 138.9 0.0 1.3e-39 136.0 0.0 1.9 1 1 0 2 2 2 2 Cytochrome P450 Fungal_trans_2 PF11951.3 ETS81681.1 - 3.6e-27 94.9 9.1 2.7e-26 92.0 6.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4281 PF14108.1 ETS81681.1 - 0.0092 16.0 0.1 0.094 12.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4281) zf-RING_2 PF13639.1 ETS81682.1 - 2.5e-10 40.0 4.8 2.5e-10 40.0 3.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 ETS81682.1 - 0.00019 21.4 3.0 0.00019 21.4 2.1 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS81682.1 - 0.00051 19.8 2.5 0.00051 19.8 1.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETS81682.1 - 0.00054 19.6 5.2 0.00054 19.6 3.6 2.1 2 0 0 2 2 1 1 zinc-RING finger domain PHD PF00628.24 ETS81682.1 - 0.0018 17.9 5.6 0.0039 16.8 3.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 ETS81682.1 - 0.0018 18.2 5.0 0.0018 18.2 3.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 ETS81682.1 - 0.0023 17.6 2.1 0.0023 17.6 1.4 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 1 FANCL_C PF11793.3 ETS81682.1 - 0.0029 17.5 5.3 0.0029 17.5 3.7 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 ETS81682.1 - 0.0058 16.2 3.5 0.0058 16.2 2.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 ETS81682.1 - 0.016 15.1 3.9 0.039 13.8 2.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger SWIM PF04434.12 ETS81682.1 - 0.058 12.8 2.2 0.12 11.8 1.5 1.6 1 0 0 1 1 1 0 SWIM zinc finger zf-RING_4 PF14570.1 ETS81682.1 - 1.8 8.1 14.3 0.063 12.8 5.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CDC45 PF02724.9 ETS81682.1 - 4.7 5.1 6.2 6.4 4.6 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_28 PF00295.12 ETS81683.1 - 2.7e-98 328.9 20.9 3.4e-98 328.5 14.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS81683.1 - 0.0028 17.4 38.8 0.19 11.4 26.9 3.1 1 1 0 1 1 1 1 Right handed beta helix region Ferritin_2 PF13668.1 ETS81685.1 - 9.9e-18 64.4 0.0 2.1e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain DUF525 PF04379.9 ETS81685.1 - 0.11 12.4 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF525) WD40 PF00400.27 ETS81686.1 - 9.4e-17 60.1 5.1 0.0031 17.3 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CDC45 PF02724.9 ETS81686.1 - 1.2 7.0 15.7 1.5 6.7 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 ETS81686.1 - 7.4 4.3 28.0 10 3.9 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family F-box PF00646.28 ETS81688.1 - 0.00067 19.2 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS81688.1 - 0.048 13.3 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 0 F-box-like Pex19 PF04614.7 ETS81689.1 - 1.3e-65 221.5 16.1 1.3e-65 221.5 11.1 1.6 2 0 0 2 2 2 1 Pex19 protein family Rotamase_3 PF13616.1 ETS81689.1 - 0.15 12.2 1.8 0.39 10.9 1.2 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF4407 PF14362.1 ETS81689.1 - 5.7 5.8 6.9 0.29 10.0 0.6 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) ABC1 PF03109.11 ETS81691.1 - 1.2e-32 112.3 0.0 2.1e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.10 ETS81694.1 - 6.9e-62 207.7 0.0 1.1e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RNA_pol_Rpb1_1 PF04997.7 ETS81695.1 - 3.6e-86 289.4 0.3 5.3e-86 288.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 ETS81695.1 - 1.7e-85 286.6 0.1 3.4e-85 285.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETS81695.1 - 1.3e-66 223.6 0.0 3.6e-66 222.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 ETS81695.1 - 1.4e-39 135.3 0.0 3.2e-39 134.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 ETS81695.1 - 7.1e-28 96.5 0.0 2.7e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF92 PF01940.11 ETS81696.1 - 4.1e-62 209.2 5.5 5.7e-62 208.8 3.8 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Glyco_hydro_43 PF04616.9 ETS81697.1 - 2.4e-34 118.7 10.8 2.4e-34 118.7 7.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GATA PF00320.22 ETS81698.1 - 1.5e-12 46.6 1.3 4.5e-12 45.1 0.9 1.9 1 0 0 1 1 1 1 GATA zinc finger zf-C2H2_4 PF13894.1 ETS81698.1 - 0.0033 17.6 5.8 3.4 8.2 0.0 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger DZR PF12773.2 ETS81698.1 - 0.15 11.9 5.7 6.4 6.6 0.3 4.1 4 1 0 4 4 4 0 Double zinc ribbon Vps51 PF08700.6 ETS81699.1 - 0.0072 16.1 1.3 0.11 12.3 0.0 3.3 3 1 0 3 3 3 1 Vps51/Vps67 Kinesin-related PF06548.6 ETS81699.1 - 0.015 13.9 2.6 0.023 13.2 1.8 1.3 1 0 0 1 1 1 0 Kinesin-related CorA PF01544.13 ETS81699.1 - 0.14 11.1 6.7 0.096 11.6 3.0 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TBPIP PF07106.8 ETS81699.1 - 0.34 10.4 3.3 2.1 7.8 0.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PNP_UDP_1 PF01048.15 ETS81700.1 - 2.4e-10 39.7 0.0 4.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.11 ETS81701.1 - 1.7e-27 96.1 23.6 1.7e-27 96.1 16.3 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 ETS81702.1 - 3e-50 169.8 0.3 4.5e-50 169.2 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS81702.1 - 3.1e-07 29.9 0.0 5.2e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS81702.1 - 1.2e-05 25.1 0.1 2.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.22 ETS81702.1 - 0.079 12.7 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family FMN_dh PF01070.13 ETS81703.1 - 1.7e-110 369.2 0.0 2.2e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS81703.1 - 5.8e-20 70.8 0.0 1.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS81703.1 - 0.00015 20.8 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS81703.1 - 0.002 17.0 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ETS81703.1 - 0.073 12.1 0.3 1.2 8.2 0.0 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Aldo_ket_red PF00248.16 ETS81704.1 - 1.2e-66 224.4 0.0 1.5e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRI9 PF08195.6 ETS81704.1 - 0.049 13.2 0.2 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 TRI9 protein Zn_clus PF00172.13 ETS81705.1 - 6.1e-06 26.0 8.7 9.5e-06 25.4 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS81705.1 - 0.022 13.6 0.4 0.071 11.9 0.2 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS81706.1 - 1.3e-92 310.7 22.0 1.5e-92 310.5 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81706.1 - 3.7e-19 68.6 58.7 1.2e-16 60.4 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BNR_2 PF13088.1 ETS81707.1 - 1.5e-64 217.9 0.6 1.9e-64 217.5 0.4 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 ETS81707.1 - 1.2e-05 24.3 6.3 0.037 13.8 0.1 4.6 4 0 0 4 4 4 2 BNR/Asp-box repeat BNR_3 PF13859.1 ETS81707.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 BNR repeat-like domain Glyco_hydro_43 PF04616.9 ETS81707.1 - 0.052 12.6 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 DHDPS PF00701.17 ETS81708.1 - 1.6e-44 151.6 0.0 2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HET PF06985.6 ETS81709.1 - 1.4e-26 93.3 0.2 6.2e-26 91.2 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS81710.1 - 9.8e-27 93.8 0.2 2e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 ETS81711.1 - 0.00029 20.4 0.0 0.00069 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS81711.1 - 0.0008 19.0 0.1 0.0024 17.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Ldh_2 PF02615.9 ETS81712.1 - 9.3e-96 320.4 0.0 1.1e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.13 ETS81713.1 - 1.8e-30 105.6 2.0 1.9e-30 105.6 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81713.1 - 0.0067 16.3 3.3 0.013 15.3 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 ETS81713.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.19 ETS81714.1 - 5.5e-69 232.8 27.2 7.9e-69 232.3 18.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS81714.1 - 4.7e-24 84.7 27.5 4.7e-24 84.7 19.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS81714.1 - 0.0006 18.1 4.0 0.0006 18.1 2.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ILVD_EDD PF00920.16 ETS81715.1 - 2.5e-162 540.9 1.2 2.8e-162 540.7 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Inhibitor_I78 PF11720.3 ETS81715.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I78 family FA_desaturase PF00487.19 ETS81717.1 - 1.4e-32 113.2 13.9 1.9e-32 112.7 9.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 ETS81717.1 - 2.1e-19 68.4 0.2 3.7e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 ETS81718.1 - 3e-26 91.1 0.2 5.4e-26 90.3 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 ETS81718.1 - 0.0091 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) Mnd1 PF03962.10 ETS81718.1 - 0.018 14.7 1.4 0.028 14.0 1.0 1.2 1 0 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 ETS81718.1 - 0.066 13.5 0.3 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) FixG_C PF11614.3 ETS81718.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SlyX PF04102.7 ETS81718.1 - 0.71 10.2 3.3 1.7 9.0 2.3 1.7 1 0 0 1 1 1 0 SlyX UBA PF00627.26 ETS81719.1 - 6.6e-05 22.6 0.0 0.00019 21.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 ETS81719.1 - 0.0034 17.3 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 UBX domain zf-C2H2 PF00096.21 ETS81719.1 - 0.055 13.8 0.1 0.091 13.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF572 PF04502.8 ETS81719.1 - 0.3 10.2 22.3 0.42 9.7 15.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) BTV_NS2 PF04514.7 ETS81719.1 - 1.9 7.3 14.6 2.4 6.9 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CAF-1_p150 PF11600.3 ETS81719.1 - 3.8 6.8 35.5 5.5 6.3 24.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ndc1_Nup PF09531.5 ETS81719.1 - 4.8 5.4 8.9 6 5.1 6.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 ETS81719.1 - 5.2 4.6 12.6 5.9 4.4 8.7 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 ETS81719.1 - 7.5 4.4 13.2 8.8 4.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 ETS81720.1 - 3.9e-26 91.2 11.5 4.7e-26 90.9 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 ETS81721.1 - 1.1e-44 151.7 4.3 1.2e-28 99.8 0.1 5.2 2 2 2 5 5 5 3 Protein of unknown function (DUF2408) Pex19 PF04614.7 ETS81721.1 - 0.01 15.4 0.6 0.021 14.4 0.4 1.5 1 0 0 1 1 1 0 Pex19 protein family Tropomyosin_1 PF12718.2 ETS81721.1 - 0.027 14.3 4.9 0.061 13.1 1.5 2.5 2 1 1 3 3 3 0 Tropomyosin like MitMem_reg PF13012.1 ETS81721.1 - 0.063 13.3 1.8 0.47 10.5 0.3 2.5 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function XhlA PF10779.4 ETS81721.1 - 0.082 12.8 7.1 4.8 7.1 0.0 4.0 3 1 0 3 3 3 0 Haemolysin XhlA TBPIP PF07106.8 ETS81721.1 - 0.082 12.4 4.5 0.26 10.8 3.1 1.8 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-Tim10_DDP PF02953.10 ETS81721.1 - 0.091 12.0 0.1 9.5 5.5 0.0 2.8 3 0 0 3 3 3 0 Tim10/DDP family zinc finger F_actin_bind PF08919.5 ETS81721.1 - 0.12 12.0 4.8 11 5.7 0.0 3.6 2 1 1 3 3 3 0 F-actin binding DUF1664 PF07889.7 ETS81721.1 - 0.14 11.9 2.1 0.85 9.4 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S15 PF00312.17 ETS81721.1 - 0.18 11.5 4.1 0.77 9.5 0.1 3.1 2 1 1 3 3 3 0 Ribosomal protein S15 Snapin_Pallidin PF14712.1 ETS81721.1 - 0.37 11.1 7.7 0.61 10.4 2.3 3.6 3 1 1 4 4 4 0 Snapin/Pallidin Fib_alpha PF08702.5 ETS81721.1 - 0.49 10.5 7.8 0.26 11.4 0.9 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2115 PF09888.4 ETS81721.1 - 0.6 10.1 3.1 0.89 9.6 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Sec8_exocyst PF04048.9 ETS81721.1 - 1.1 8.8 5.3 3.5 7.2 0.3 3.1 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CENP-H PF05837.7 ETS81721.1 - 1.2 9.3 5.7 0.46 10.6 1.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spectrin PF00435.16 ETS81721.1 - 2.8 8.2 8.0 0.31 11.3 0.7 2.9 3 1 0 3 3 3 0 Spectrin repeat GvpK PF05121.7 ETS81721.1 - 9.7 6.0 7.8 15 5.4 0.1 3.8 2 1 1 3 3 3 0 Gas vesicle protein K YCII PF03795.9 ETS81722.1 - 4e-10 39.7 0.0 5.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain adh_short PF00106.20 ETS81723.1 - 2.3e-15 56.8 0.1 4.3e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81723.1 - 2.5e-07 30.5 0.1 3.7e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS81724.1 - 2.9e-32 111.8 7.1 3.7e-32 111.5 4.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS81724.1 - 1.1e-31 110.4 0.4 1.3e-31 110.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS81724.1 - 7.9e-17 61.4 3.5 1.1e-16 60.9 2.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS81724.1 - 9.5e-06 25.2 2.2 2e-05 24.1 1.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 ETS81724.1 - 0.033 14.6 0.3 0.46 11.0 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 ETS81724.1 - 0.053 13.0 0.9 2.2 7.8 0.4 2.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 ETS81724.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 ETS81724.1 - 0.13 11.2 0.8 0.27 10.2 0.4 1.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 ETS81724.1 - 0.14 12.0 1.3 0.38 10.5 0.9 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 ETS81725.1 - 1.4e-33 116.1 0.0 1.2e-31 109.8 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS81726.1 - 4.1e-22 78.8 0.0 7.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.3 ETS81727.1 - 2e-30 104.7 12.5 1.3e-18 66.8 0.7 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Ferric_reduct PF01794.14 ETS81728.1 - 2.8e-13 50.0 18.6 2.8e-13 50.0 12.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS81728.1 - 9e-10 38.3 0.0 4.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 ETS81728.1 - 2.3e-08 34.0 0.0 3.5e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETS81728.1 - 0.087 13.4 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain HET PF06985.6 ETS81729.1 - 1.4e-31 109.5 0.0 2.7e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 ETS81731.1 - 5.1e-08 33.0 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81731.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 ETS81731.1 - 0.15 11.5 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L37ae PF01780.14 ETS81732.1 - 0.035 13.9 0.1 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4470 PF14737.1 ETS81734.1 - 2e-12 46.6 0.0 4.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 ETS81734.1 - 1.4e-09 37.6 17.6 3e-09 36.5 12.2 1.6 1 0 0 1 1 1 1 MYND finger TauD PF02668.11 ETS81735.1 - 1.8e-43 149.1 0.2 2.2e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pectate_lyase_3 PF12708.2 ETS81736.1 - 7.6e-66 222.4 13.2 2e-57 194.8 3.4 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 ETS81736.1 - 0.00013 21.3 0.3 0.021 14.2 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase WSC PF01822.14 ETS81740.1 - 1.8e-66 220.0 72.9 2.5e-18 65.7 5.9 5.0 6 0 0 6 6 6 4 WSC domain Sporozoite_P67 PF05642.6 ETS81740.1 - 1.9 6.2 9.8 3.2 5.4 6.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.17 ETS81741.1 - 1.4e-66 224.9 0.0 1.9e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 ETS81742.1 - 6.4e-23 80.5 0.7 1.3e-22 79.5 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS81742.1 - 7.2e-17 61.1 0.1 1.1e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS81742.1 - 0.00037 21.3 0.0 0.00066 20.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase H_lectin PF09458.5 ETS81742.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 H-type lectin domain DUF3425 PF11905.3 ETS81743.1 - 1.3e-13 51.0 2.5 2.3e-13 50.1 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FlgD PF03963.9 ETS81743.1 - 0.0054 16.7 0.3 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region HET PF06985.6 ETS81746.1 - 1.8e-14 54.0 6.2 5.3e-14 52.5 2.0 3.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS81747.1 - 6.5e-70 235.9 0.0 7.8e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EHN PF06441.7 ETS81748.1 - 1.9e-34 117.9 0.9 2.3e-33 114.4 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS81748.1 - 2.5e-12 47.1 0.6 5.7e-12 46.0 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS81748.1 - 0.00011 21.8 0.2 0.0002 21.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2964 PF11177.3 ETS81749.1 - 0.23 11.4 6.1 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Methyltransf_2 PF00891.13 ETS81750.1 - 5.3e-25 88.0 0.1 7.9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 ETS81752.1 - 3.5e-13 49.8 0.0 6.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81752.1 - 6.1e-11 42.8 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81752.1 - 8.4e-11 41.6 0.0 1.3e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81752.1 - 1.9e-09 37.8 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81752.1 - 3.9e-08 33.6 0.2 8.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS81752.1 - 2e-07 30.8 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS81752.1 - 2.1e-05 24.5 0.0 3.3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS81752.1 - 5.8e-05 22.3 0.2 0.0001 21.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 ETS81752.1 - 0.00013 21.1 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS81752.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 ETS81752.1 - 0.035 13.4 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 ETS81752.1 - 0.054 12.9 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase N6_Mtase PF02384.11 ETS81752.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase MFS_1 PF07690.11 ETS81753.1 - 7.5e-39 133.4 53.5 4.5e-29 101.2 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81753.1 - 1.1e-10 40.6 29.2 4.6e-09 35.3 5.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS81753.1 - 0.0043 16.8 0.1 0.041 13.6 0.0 2.6 2 1 0 2 2 2 1 MFS_1 like family DIOX_N PF14226.1 ETS81754.1 - 8.1e-18 65.0 0.2 1.2e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS81754.1 - 1.9e-13 50.5 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 ETS81755.1 - 2.9e-21 76.0 5.2 9.7e-18 64.6 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PspA_IM30 PF04012.7 ETS81756.1 - 0.012 14.9 0.4 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family Sugarporin_N PF11471.3 ETS81756.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4140 PF13600.1 ETS81756.1 - 0.19 12.1 1.5 0.33 11.4 0.5 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) His_Phos_1 PF00300.17 ETS81757.1 - 7e-17 61.9 0.2 1.2e-16 61.1 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WI12 PF07107.6 ETS81757.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Wound-induced protein WI12 zf-RING_2 PF13639.1 ETS81758.1 - 4.2e-07 29.6 2.9 4.2e-07 29.6 2.0 2.2 1 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETS81758.1 - 4.2e-05 23.1 2.3 0.00011 21.8 1.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS81758.1 - 0.00046 20.1 1.9 0.0013 18.7 1.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS81758.1 - 0.0012 18.4 1.6 0.0012 18.4 1.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS81758.1 - 0.01 15.9 0.8 0.025 14.6 0.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Mito_carr PF00153.22 ETS81759.1 - 1.4e-69 229.8 1.9 5.4e-23 80.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 ETS81760.1 - 3.4e-45 152.1 1.0 3.9e-45 151.9 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SMC_hinge PF06470.8 ETS81760.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Anp1 PF03452.9 ETS81761.1 - 1.4e-108 362.1 0.0 1.7e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF3328 PF11807.3 ETS81761.1 - 0.04 13.6 0.2 0.079 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) HhH-GPD PF00730.20 ETS81762.1 - 3.4e-16 59.4 0.0 9.4e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Recep_L_domain PF01030.19 ETS81763.1 - 5.2e-07 29.6 0.2 0.8 9.7 0.0 4.8 1 1 3 5 5 5 3 Receptor L domain Ecm33 PF12454.3 ETS81763.1 - 0.0022 17.8 0.3 0.0083 15.9 0.2 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein G-patch PF01585.18 ETS81764.1 - 1.1e-11 44.3 2.7 3.9e-11 42.5 1.8 2.0 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 ETS81764.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS81764.1 - 0.0032 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS81764.1 - 0.027 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YqfQ PF14181.1 ETS81764.1 - 0.027 14.4 0.6 0.027 14.4 0.4 2.7 3 0 0 3 3 3 0 YqfQ-like protein Nup35_RRM_2 PF14605.1 ETS81764.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.23 ETS81765.1 - 3.5e-85 285.9 0.0 4.1e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS81765.1 - 2.9e-14 53.7 0.5 8.4e-14 52.2 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 ETS81765.1 - 0.0016 17.0 0.0 0.029 12.9 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter PUL PF08324.6 ETS81766.1 - 0.11 11.3 0.1 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 PUL domain DUF3110 PF11360.3 ETS81766.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dynamin_N PF00350.18 ETS81767.1 - 7.2e-30 104.0 0.2 7.2e-30 104.0 0.1 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 ETS81767.1 - 3.2e-16 58.9 0.0 6.9e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 ETS81767.1 - 7.5e-07 29.1 0.0 3.3e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 ETS81767.1 - 0.00049 19.9 1.8 0.0016 18.2 1.3 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain FeoB_N PF02421.13 ETS81767.1 - 0.0081 15.4 0.0 0.5 9.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.1 ETS81767.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 ETS81767.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 ETS81767.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain HR1 PF02185.11 ETS81767.1 - 0.026 14.2 3.3 3 7.6 1.6 3.0 3 0 0 3 3 3 0 Hr1 repeat ABC_tran PF00005.22 ETS81767.1 - 0.032 14.5 0.3 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 ETS81767.1 - 7.4 6.8 6.9 0.48 10.7 0.2 2.4 2 2 0 2 2 2 0 AAA domain HET PF06985.6 ETS81768.1 - 8.8e-32 110.1 0.0 1.7e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 ETS81771.1 - 4e-19 69.4 2.5 5.2e-19 69.0 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81771.1 - 8.8e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS81771.1 - 0.0047 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS81771.1 - 0.0056 16.3 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 ETS81771.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.3 1 1 0 1 1 1 0 Putative serine esterase (DUF676) CorA PF01544.13 ETS81772.1 - 4.8e-11 42.2 0.9 2.2e-10 40.0 0.1 2.2 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein ICE2 PF08426.5 ETS81773.1 - 1.4e-138 461.9 8.8 1.6e-138 461.7 6.1 1.0 1 0 0 1 1 1 1 ICE2 WHG PF13305.1 ETS81774.1 - 0.041 14.4 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 WHG domain Hydrolase_6 PF13344.1 ETS81775.1 - 6.1e-29 99.8 0.0 2.8e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS81775.1 - 1.6e-15 56.5 0.1 1.5e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 ETS81775.1 - 3.2e-05 24.4 0.0 0.017 15.5 0.0 2.6 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS81775.1 - 0.00025 21.2 0.0 0.085 13.0 0.0 3.5 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS81775.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 ETS81777.1 - 5.2e-27 94.7 0.0 1e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS81777.1 - 7.7e-21 74.8 0.4 2.6e-20 73.1 0.2 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS81777.1 - 3e-08 32.9 0.0 0.00037 19.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS81777.1 - 6.6e-08 31.8 0.1 5e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS81777.1 - 2.3e-05 24.3 0.0 8.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS81777.1 - 2.9e-05 24.0 0.0 8.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS81777.1 - 0.00063 19.8 0.0 0.013 15.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS81777.1 - 0.002 16.7 0.0 0.0057 15.1 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DOMON PF03351.12 ETS81777.1 - 0.0067 16.3 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 DOMON domain Lycopene_cycl PF05834.7 ETS81777.1 - 0.017 14.0 0.1 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 ETS81777.1 - 0.023 15.0 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS81777.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 ETS81777.1 - 0.12 12.3 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF3439 PF11921.3 ETS81777.1 - 4.3 7.0 14.8 10 5.9 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_61 PF03443.9 ETS81778.1 - 1e-40 139.9 0.7 1.2e-40 139.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF159 PF02586.9 ETS81779.1 - 3.8e-54 183.3 0.0 6.6e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Ribosomal_L18e PF00828.14 ETS81780.1 - 2.1e-24 86.3 0.0 2.1e-24 86.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 ETS81781.1 - 7.8e-76 249.9 0.5 2.1e-26 91.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 ETS81782.1 - 3.5e-12 45.7 0.0 4.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS81782.1 - 5.4e-08 32.7 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS81782.1 - 2.7e-07 30.3 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS81782.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif C2 PF00168.25 ETS81783.1 - 1.3e-13 50.5 0.0 2.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Abhydrolase_4 PF08386.5 ETS81784.1 - 1.2e-22 79.6 0.0 2.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS81784.1 - 4.7e-14 52.4 0.2 9.3e-10 38.4 0.0 3.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS81784.1 - 2.4e-12 47.2 0.7 1.2e-11 44.9 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81784.1 - 1.4e-05 24.9 0.0 0.061 13.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Kinetocho_Slk19 PF12709.2 ETS81785.1 - 1.6e-18 66.5 8.1 1.6e-18 66.5 5.6 4.7 3 1 2 5 5 5 2 Central kinetochore-associated IncA PF04156.9 ETS81785.1 - 0.00061 19.4 8.6 0.00061 19.4 6.0 2.9 2 1 0 2 2 2 1 IncA protein Tropomyosin_1 PF12718.2 ETS81785.1 - 0.0017 18.2 19.1 0.0017 18.2 13.2 4.1 3 1 1 4 4 4 1 Tropomyosin like DUF2570 PF10828.3 ETS81785.1 - 0.0087 15.6 3.0 0.0087 15.6 2.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2570) PspA_IM30 PF04012.7 ETS81785.1 - 0.62 9.3 44.0 0.097 12.0 12.9 3.5 1 1 2 3 3 3 0 PspA/IM30 family DUF3584 PF12128.3 ETS81785.1 - 0.68 7.1 33.9 0.049 10.9 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2730 PF10805.3 ETS81785.1 - 2.1 8.1 13.7 0.48 10.1 0.8 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) Bacillus_HBL PF05791.6 ETS81785.1 - 6.7 6.0 15.8 0.12 11.6 1.5 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) zf-CCHC PF00098.18 ETS81786.1 - 0.009 15.9 0.8 0.009 15.9 0.5 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETS81786.1 - 0.17 11.5 0.9 0.62 9.7 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle PHD PF00628.24 ETS81786.1 - 0.33 10.6 2.1 0.67 9.6 1.5 1.5 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_28 PF00295.12 ETS81787.1 - 4.5e-96 321.6 18.5 7.4e-96 320.9 12.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS81787.1 - 3.7e-06 26.7 22.2 3.7e-06 26.7 15.4 3.5 2 1 0 2 2 2 1 Right handed beta helix region SNARE PF05739.14 ETS81788.1 - 1.6e-14 53.2 7.1 1.6e-14 53.2 4.9 2.7 3 1 1 4 4 3 1 SNARE domain Syntaxin PF00804.20 ETS81788.1 - 2.1e-05 24.5 3.0 2.1e-05 24.5 2.1 2.7 2 1 0 2 2 2 1 Syntaxin Use1 PF09753.4 ETS81788.1 - 2.7e-05 23.7 7.8 4.7e-05 22.9 5.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rifin_STEVOR PF02009.11 ETS81788.1 - 0.0008 19.1 5.2 0.0008 19.1 3.6 2.2 1 1 0 2 2 2 1 Rifin/stevor family DUF2207 PF09972.4 ETS81788.1 - 0.0014 17.3 0.9 0.0024 16.5 0.6 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1510 PF07423.6 ETS81788.1 - 0.0018 17.6 0.5 0.0018 17.6 0.3 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1510) DUF912 PF06024.7 ETS81788.1 - 0.011 15.7 1.5 0.011 15.7 1.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ferritin PF00210.19 ETS81788.1 - 0.012 15.3 1.9 0.038 13.7 0.0 2.2 2 0 0 2 2 2 0 Ferritin-like domain Synaptobrevin PF00957.16 ETS81788.1 - 0.015 14.9 4.9 0.053 13.1 3.4 2.0 1 0 0 1 1 1 0 Synaptobrevin EphA2_TM PF14575.1 ETS81788.1 - 0.017 15.4 0.7 0.062 13.6 0.5 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 ETS81788.1 - 0.022 14.2 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.1 ETS81788.1 - 0.022 14.8 0.7 0.051 13.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) GRIM-19 PF06212.7 ETS81788.1 - 0.029 14.0 1.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 GRIM-19 protein LRRC37AB_C PF14914.1 ETS81788.1 - 0.04 13.3 2.7 0.075 12.4 1.8 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF843 PF05814.6 ETS81788.1 - 0.051 13.3 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Baculo_11_kDa PF06143.6 ETS81788.1 - 0.064 12.6 1.3 0.27 10.6 0.9 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family MFS_2 PF13347.1 ETS81788.1 - 0.097 11.0 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein O-antigen_lig PF13425.1 ETS81788.1 - 0.11 12.4 0.4 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Colicin-DNase PF12639.2 ETS81788.1 - 0.11 12.7 2.9 0.17 12.1 0.2 2.4 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin ATP-synt_8 PF00895.15 ETS81788.1 - 0.12 12.5 0.6 0.3 11.3 0.4 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 Tweety PF04906.8 ETS81788.1 - 0.15 10.4 8.0 0.13 10.6 2.6 2.0 2 0 0 2 2 2 0 Tweety BLOC1_2 PF10046.4 ETS81788.1 - 0.16 12.1 6.3 2.5 8.3 1.3 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RunxI PF08504.6 ETS81788.1 - 0.26 11.7 2.5 0.3 11.5 0.4 2.1 2 1 0 2 2 1 0 Runx inhibition domain IFT57 PF10498.4 ETS81788.1 - 0.57 8.8 16.7 0.091 11.4 2.6 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4179 PF13786.1 ETS81788.1 - 1.2 9.4 5.4 0.91 9.7 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2393 PF09624.5 ETS81788.1 - 1.9 8.0 5.7 0.24 10.9 1.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2393) V-SNARE PF05008.10 ETS81788.1 - 2 8.6 17.1 3.9 7.7 4.7 4.0 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus ASFV_J13L PF05568.6 ETS81788.1 - 2.1 7.8 6.7 0.41 10.1 1.5 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF2203 PF09969.4 ETS81788.1 - 2.3 8.4 10.8 4.7 7.4 1.8 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.8 ETS81788.1 - 3.7 6.5 8.3 2.9 6.8 1.3 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF1993 PF09351.5 ETS81788.1 - 3.9 7.3 9.5 2.1 8.2 1.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1993) Syntaxin_2 PF14523.1 ETS81788.1 - 7.4 6.6 17.8 0.24 11.4 3.5 2.8 1 1 1 2 2 2 0 Syntaxin-like protein RCR PF12273.3 ETS81789.1 - 3.2e-08 34.1 6.7 5.2e-08 33.5 4.6 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 ETS81789.1 - 0.00096 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PspB PF06667.7 ETS81789.1 - 0.11 12.4 0.5 0.16 11.9 0.4 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF680 PF05079.7 ETS81790.1 - 0.27 11.7 4.5 0.29 11.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF680) tRNA-synt_2c PF01411.14 ETS81791.1 - 3.1e-215 715.6 0.1 3.1e-215 715.6 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 ETS81791.1 - 6.7e-16 57.9 0.4 1.6e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 ETS81791.1 - 0.04 13.6 0.3 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 DHHA1 domain 5-FTHF_cyc-lig PF01812.15 ETS81792.1 - 7.3e-09 35.6 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family FYVE_2 PF02318.11 ETS81793.1 - 0.46 10.3 4.4 0.18 11.6 0.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.16 ETS81793.1 - 1.2 9.0 8.7 6.3 6.7 6.0 2.2 1 1 0 1 1 1 0 IBR domain Siva PF05458.7 ETS81793.1 - 2.4 7.6 12.5 96 2.4 8.6 2.9 1 1 0 1 1 1 0 Cd27 binding protein (Siva) DnaJ-X PF14308.1 ETS81794.1 - 7.1e-72 240.9 1.1 7.1e-72 240.9 0.8 2.3 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 ETS81794.1 - 1e-25 89.2 1.1 3e-25 87.7 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.12 ETS81795.1 - 7.3e-18 64.4 0.0 1.8e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 ETS81795.1 - 1.8e-15 57.0 0.0 3.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS81795.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS81795.1 - 0.00016 21.5 0.1 0.00043 20.2 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS81795.1 - 0.00037 19.2 0.1 0.002 16.8 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS81795.1 - 0.00094 18.1 0.0 0.0045 15.9 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein KR PF08659.5 ETS81795.1 - 0.004 16.8 0.2 0.02 14.5 0.0 1.9 1 1 1 2 2 2 1 KR domain C2-set_2 PF08205.7 ETS81795.1 - 0.13 12.1 0.3 0.27 11.1 0.1 1.5 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain SQS_PSY PF00494.14 ETS81796.1 - 7.3e-40 136.9 0.0 3.6e-39 134.6 0.0 1.8 2 0 0 2 2 2 1 Squalene/phytoene synthase Glyco_hydro_42 PF02449.10 ETS81796.1 - 0.031 13.3 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Peptidase_S8 PF00082.17 ETS81797.1 - 7.5e-45 153.2 15.0 1.2e-44 152.5 10.4 1.3 1 0 0 1 1 1 1 Subtilase family CNH PF00780.17 ETS81797.1 - 0.033 13.6 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 CNH domain F-box-like PF12937.2 ETS81798.1 - 0.027 14.2 0.4 0.082 12.6 0.3 1.9 1 0 0 1 1 1 0 F-box-like Mannosyl_trans PF05007.8 ETS81799.1 - 1.1e-77 261.2 9.6 1.7e-77 260.6 6.6 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 ETS81799.1 - 5.5e-12 45.2 5.4 5.5e-12 45.2 3.7 2.3 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 ETS81799.1 - 3e-05 23.6 29.4 3e-05 23.6 20.4 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF2029) Translin PF01997.11 ETS81800.1 - 3.4e-51 173.6 0.0 4.7e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Translin family DUF3450 PF11932.3 ETS81800.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HXXSHH PF07586.6 ETS81800.1 - 0.13 11.1 0.2 0.32 9.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Pkinase PF00069.20 ETS81801.1 - 5.3e-29 101.1 0.0 2.6e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS81801.1 - 4.3e-16 58.7 0.0 2.3e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 ETS81801.1 - 0.00086 18.4 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS81801.1 - 0.02 14.2 0.5 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family FERM_M PF00373.13 ETS81801.1 - 0.058 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 FERM central domain ABC_tran PF00005.22 ETS81802.1 - 5.8e-47 159.4 0.1 1e-28 100.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS81802.1 - 4.6e-33 114.7 38.2 1.6e-23 83.5 6.2 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS81802.1 - 1e-13 51.9 0.0 0.0037 17.2 0.0 4.5 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 ETS81802.1 - 4.1e-12 45.8 0.9 4.2e-05 22.8 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS81802.1 - 3.6e-08 32.8 0.6 0.002 17.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS81802.1 - 2.1e-07 31.7 0.1 0.014 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS81802.1 - 6.8e-07 29.4 5.5 0.00051 20.0 0.3 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 ETS81802.1 - 3.5e-06 26.6 0.1 0.057 12.8 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 ETS81802.1 - 5.7e-06 26.7 4.6 0.02 15.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 ETS81802.1 - 1.9e-05 24.5 0.0 0.35 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 ETS81802.1 - 2.7e-05 24.0 0.5 0.013 15.3 0.1 2.7 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 ETS81802.1 - 3e-05 24.1 2.4 0.031 14.4 0.2 3.4 2 2 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS81802.1 - 4.4e-05 22.5 0.4 0.1 11.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 ETS81802.1 - 6.6e-05 22.4 0.1 0.0077 15.7 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETS81802.1 - 8.4e-05 22.5 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 ETS81802.1 - 0.0001 22.7 0.0 0.063 13.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 ETS81802.1 - 0.00015 21.2 0.9 0.51 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 ETS81802.1 - 0.0002 21.0 0.1 0.65 9.6 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 ETS81802.1 - 0.00029 21.1 0.1 0.46 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 ETS81802.1 - 0.00059 19.0 0.3 0.98 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 ETS81802.1 - 0.0007 19.4 1.2 0.003 17.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 ETS81802.1 - 0.001 18.9 0.2 1.4 8.8 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 ETS81802.1 - 0.0012 18.5 0.4 1.7 8.4 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 ETS81802.1 - 0.0017 18.2 0.0 0.58 10.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF2975 PF11188.3 ETS81802.1 - 0.0033 17.1 2.0 0.0033 17.1 1.4 4.8 5 0 0 5 5 4 1 Protein of unknown function (DUF2975) AAA_30 PF13604.1 ETS81802.1 - 0.014 14.9 0.0 1.1 8.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS81802.1 - 0.016 14.2 0.2 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 ETS81802.1 - 0.017 14.8 0.3 0.82 9.3 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase GTP_EFTU PF00009.22 ETS81802.1 - 0.018 14.4 0.2 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 ETS81802.1 - 0.018 13.6 1.3 0.72 8.3 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Adeno_IVa2 PF02456.10 ETS81802.1 - 0.019 13.6 0.0 2.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein zf-ISL3 PF14690.1 ETS81802.1 - 0.039 14.0 0.1 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 NACHT PF05729.7 ETS81802.1 - 0.055 13.1 2.3 4.2 6.9 0.0 3.3 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.10 ETS81802.1 - 0.72 9.5 1.8 3 7.5 0.1 2.4 2 0 0 2 2 2 0 NTPase cobW PF02492.14 ETS81802.1 - 1.2 8.5 5.5 13 5.2 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NAD_binding_8 PF13450.1 ETS81804.1 - 4.1e-15 55.5 0.0 8.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS81804.1 - 0.00028 19.8 0.0 0.0011 17.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS81804.1 - 0.013 15.8 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS81804.1 - 0.016 14.2 0.1 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 ETS81804.1 - 0.023 14.4 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS81804.1 - 0.037 12.8 0.0 0.11 11.2 0.0 1.8 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS81804.1 - 0.087 12.6 0.0 5.1 6.9 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.1 ETS81805.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FA_hydroxylase PF04116.8 ETS81806.1 - 4.2e-06 27.1 8.2 4.2e-06 27.1 5.7 2.9 2 2 1 3 3 3 2 Fatty acid hydroxylase superfamily LIP PF03583.9 ETS81807.1 - 2.2e-65 220.7 0.3 3.1e-65 220.2 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 ETS81807.1 - 0.0006 19.5 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS81807.1 - 0.0016 18.3 0.5 0.0024 17.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Grp1_Fun34_YaaH PF01184.14 ETS81809.1 - 1.3e-86 289.2 20.2 1.6e-86 288.9 14.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RasGAP_C PF03836.10 ETS81810.1 - 2.9e-47 159.9 3.4 9.9e-47 158.1 2.3 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 ETS81810.1 - 9.8e-40 136.3 0.0 3.5e-39 134.4 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 ETS81810.1 - 3.9e-15 53.9 39.8 0.031 13.8 0.9 13.1 14 0 0 14 14 14 6 IQ calmodulin-binding motif CH PF00307.26 ETS81810.1 - 1.8e-09 37.5 0.0 5.5e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 ETS81811.1 - 4.4e-130 433.6 3.4 5.5e-130 433.3 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 ETS81811.1 - 2.4e-13 49.6 0.0 3.4e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 ETS81811.1 - 4.6e-07 29.0 1.7 4.7e-06 25.7 0.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 ETS81811.1 - 9.7e-06 24.9 9.2 0.028 13.5 0.0 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 ETS81811.1 - 0.0023 17.2 3.0 0.0091 15.2 1.1 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein PK PF00224.16 ETS81811.1 - 0.04 12.5 0.0 0.13 10.8 0.0 1.8 2 1 0 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.9 ETS81811.1 - 0.067 12.2 1.2 0.16 11.0 0.2 2.0 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG Cuticle_1 PF08140.6 ETS81811.1 - 0.11 12.3 0.9 12 5.8 0.2 2.8 2 0 0 2 2 2 0 Crustacean cuticle protein repeat TFR_dimer PF04253.10 ETS81812.1 - 1.5e-20 73.0 0.0 2.6e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS81812.1 - 1.7e-14 53.9 0.0 3.9e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS81812.1 - 1.2e-05 24.8 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 ETS81812.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Apolipoprotein PF01442.13 ETS81812.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.11 ETS81813.1 - 3.6e-30 104.8 36.9 4.5e-25 88.0 5.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81813.1 - 6.1e-09 34.9 3.9 6.1e-09 34.9 2.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter ADH_N PF08240.7 ETS81814.1 - 5.6e-09 35.7 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS81814.1 - 0.0034 18.2 0.1 0.028 15.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 ETS81814.1 - 0.068 12.2 0.5 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) DUF805 PF05656.9 ETS81816.1 - 6.5 6.6 16.1 4.6 7.1 0.6 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Asp_protease_2 PF13650.1 ETS81818.1 - 0.00048 20.5 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 ETS81818.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Cyclin_N PF00134.18 ETS81819.1 - 9.8e-37 125.3 0.4 1.7e-36 124.5 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS81819.1 - 4.6e-11 42.6 0.3 2.5e-10 40.3 0.0 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain zf-Apc11 PF12861.2 ETS81821.1 - 6.1e-46 154.2 11.8 6.9e-46 154.0 8.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 ETS81821.1 - 1.5e-33 114.6 11.1 1.9e-33 114.4 7.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 ETS81821.1 - 7.8e-09 35.2 16.9 4.9e-08 32.6 11.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS81821.1 - 5.7e-05 22.6 13.4 0.0014 18.2 9.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS81821.1 - 0.00017 21.5 14.5 0.0012 18.8 10.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS81821.1 - 0.00033 20.2 15.4 0.0013 18.3 10.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS81821.1 - 0.00044 20.0 4.9 0.00044 20.0 3.4 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 ETS81821.1 - 0.0011 18.4 3.5 0.0011 18.4 2.4 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 ETS81821.1 - 0.003 17.5 17.2 0.053 13.4 11.9 2.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 ETS81821.1 - 0.0099 15.5 16.7 0.23 11.2 12.0 2.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 ETS81821.1 - 0.042 13.3 6.5 0.074 12.5 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 ETS81821.1 - 0.061 12.9 1.0 0.061 12.9 0.7 2.3 2 0 0 2 2 2 0 HIT zinc finger Opy2 PF09463.5 ETS81821.1 - 0.41 10.7 11.8 2.2 8.4 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein zf-DBF PF07535.7 ETS81821.1 - 0.78 9.4 3.8 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger DUF329 PF03884.9 ETS81821.1 - 1.7 8.2 7.0 1.4 8.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) RINGv PF12906.2 ETS81821.1 - 2 8.5 13.4 5.9 7.0 9.1 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 ETS81821.1 - 2.7 8.0 15.2 14 5.8 10.5 2.1 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 ETS81821.1 - 4.2 7.4 11.2 3.4 7.7 4.8 2.3 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 ETS81821.1 - 5.6 6.7 10.4 0.7 9.6 4.1 2.0 2 1 0 2 2 1 0 RING-type zinc-finger zinc-ribbons_6 PF07191.7 ETS81821.1 - 5.6 6.8 10.3 3.7 7.3 0.1 2.6 1 1 2 3 3 3 0 zinc-ribbons DZR PF12773.2 ETS81821.1 - 6.5 6.6 13.7 12 5.7 4.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.1 ETS81821.1 - 6.5 6.9 12.3 3 8.0 4.6 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain Rhodanese PF00581.15 ETS81822.1 - 2.9e-25 88.8 0.0 1.5e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.15 ETS81823.1 - 1.2e-28 98.5 1.9 1.2e-28 98.5 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 ETS81823.1 - 2.6e-20 71.4 0.0 4.9e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WSC PF01822.14 ETS81824.1 - 9.3e-16 57.5 6.5 2.4e-15 56.2 4.5 1.8 1 0 0 1 1 1 1 WSC domain Pec_lyase_C PF00544.14 ETS81825.1 - 4e-22 78.6 5.0 5.9e-22 78.1 3.5 1.3 1 0 0 1 1 1 1 Pectate lyase RRM_6 PF14259.1 ETS81826.1 - 4.2e-05 23.4 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS81826.1 - 0.0001 21.8 0.0 0.0024 17.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FKBP_C PF00254.23 ETS81828.1 - 2.2e-34 117.3 0.0 3.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TrkH PF02386.11 ETS81829.1 - 4.5e-88 295.1 9.4 5.6e-85 285.0 1.1 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.11 ETS81829.1 - 0.56 9.9 9.5 0.13 11.9 3.4 2.4 2 0 0 2 2 2 0 Ion channel IMS PF00817.15 ETS81830.1 - 1.4e-43 148.2 0.1 3.1e-43 147.1 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS81830.1 - 5.9e-16 58.5 0.0 1.8e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 ETS81830.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif AMP-binding PF00501.23 ETS81832.1 - 1.4e-29 102.7 0.0 5.2e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS81832.1 - 6.1e-26 90.8 0.0 9.3e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS81832.1 - 3.4e-10 39.7 0.0 6.2e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS81832.1 - 4.7e-06 26.7 0.0 5.6e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 ETS81832.1 - 0.0045 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 ETS81832.1 - 0.032 14.1 0.3 1 9.2 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS81832.1 - 0.048 12.3 0.0 3.1 6.4 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS81832.1 - 0.12 12.3 0.0 17 5.3 0.0 2.6 3 0 0 3 3 3 0 NADH(P)-binding BNR_2 PF13088.1 ETS81833.1 - 3.7e-12 46.1 0.5 3.3e-09 36.4 0.5 2.5 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 ETS81833.1 - 3.6e-09 35.0 5.7 0.032 14.0 0.1 4.8 4 0 0 4 4 4 3 BNR/Asp-box repeat Paired_CXXCH_1 PF09699.5 ETS81833.1 - 0.013 15.0 1.6 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) p450 PF00067.17 ETS81834.1 - 1.7e-69 234.5 0.0 2.1e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3112 PF11309.3 ETS81835.1 - 3.6e-48 163.3 19.5 1.8e-46 157.8 3.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF997 PF06196.7 ETS81835.1 - 0.8 9.2 5.3 6.2 6.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF997) adh_short PF00106.20 ETS81836.1 - 1.4e-27 96.6 0.8 1.8e-27 96.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81836.1 - 1.7e-14 53.8 0.2 2.7e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS81836.1 - 9.7e-12 45.1 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 ETS81836.1 - 0.0084 15.2 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 ETS81836.1 - 0.03 14.1 0.2 0.062 13.0 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 ETS81836.1 - 0.079 12.0 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Prefoldin_3 PF13758.1 ETS81837.1 - 1.9e-22 78.8 0.6 7.4e-22 76.9 0.4 2.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 ETS81837.1 - 6.4e-22 78.3 0.5 6.4e-22 78.3 0.3 5.2 5 2 1 6 6 6 1 Domain of unknown function (DUF3835) Death PF00531.17 ETS81837.1 - 0.021 14.5 0.3 1.6 8.5 0.3 2.4 2 0 0 2 2 2 0 Death domain CS PF04969.11 ETS81838.1 - 8.5e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 CS domain MAT1 PF06391.8 ETS81839.1 - 2.9e-31 108.6 7.1 3.8e-31 108.2 4.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 ETS81839.1 - 0.00032 20.2 4.8 0.00073 19.1 3.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 ETS81839.1 - 0.019 14.7 1.6 0.13 12.0 1.7 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 ETS81839.1 - 0.025 14.5 8.9 0.047 13.7 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS81839.1 - 0.072 12.7 6.8 0.13 11.9 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.1 ETS81839.1 - 0.12 12.6 5.1 0.17 12.1 3.5 1.2 1 0 0 1 1 1 0 AAA domain MRP-S26 PF14943.1 ETS81839.1 - 0.32 10.5 13.8 0.53 9.8 9.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.1 ETS81839.1 - 0.55 10.1 7.3 1.2 9.0 5.0 1.5 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 ETS81839.1 - 1.1 9.0 10.4 6.1 6.6 7.5 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 ETS81839.1 - 1.9 8.1 7.5 2.3 7.8 2.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ANTH PF07651.11 ETS81842.1 - 6.2e-69 231.8 1.5 8e-69 231.4 1.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 ETS81842.1 - 2e-08 34.1 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 ETS81843.1 - 4.6e-94 314.9 0.0 7.7e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 ETS81843.1 - 0.00084 18.9 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 ETS81843.1 - 0.021 14.0 0.1 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Transket_pyr PF02779.19 ETS81844.1 - 8.8e-46 155.6 0.0 1.2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS81844.1 - 4.2e-35 120.3 0.0 1.6e-34 118.5 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.5 ETS81845.1 - 1.3e-27 95.5 0.2 2.1e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 ETS81845.1 - 2.2e-22 79.3 0.0 4.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81845.1 - 1.8e-19 69.7 0.0 2.9e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS81845.1 - 1.2e-13 51.0 0.1 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81845.1 - 3.8e-13 49.6 0.0 8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81845.1 - 1.6e-12 47.9 0.0 4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS81845.1 - 2.7e-12 46.3 0.2 3.9e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 ETS81845.1 - 1.5e-11 44.6 0.0 3.7e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS81845.1 - 2.4e-11 43.2 0.0 4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS81845.1 - 5.5e-09 36.0 0.0 1.5e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 ETS81845.1 - 5.8e-05 22.6 0.1 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 ETS81845.1 - 5.9e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 ETS81845.1 - 9.3e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 ETS81845.1 - 0.00029 20.2 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 ETS81845.1 - 0.00075 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS81845.1 - 0.00099 18.3 0.1 0.0041 16.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 ETS81845.1 - 0.0033 17.1 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 ETS81845.1 - 0.0076 14.6 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 ETS81845.1 - 0.0095 15.1 0.3 0.07 12.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase TehB PF03848.9 ETS81845.1 - 0.014 14.5 0.2 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 ETS81845.1 - 0.021 15.6 0.0 0.08 13.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 ETS81845.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ORMDL PF04061.9 ETS81848.1 - 1.4e-61 206.0 3.7 1.6e-61 205.8 2.6 1.1 1 0 0 1 1 1 1 ORMDL family BAF1_ABF1 PF04684.8 ETS81849.1 - 0.0082 15.0 0.5 0.0082 15.0 0.3 1.5 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor CbiQ PF02361.11 ETS81849.1 - 0.46 10.0 4.7 0.95 8.9 3.3 1.5 1 0 0 1 1 1 0 Cobalt transport protein Methyltransf_3 PF01596.12 ETS81850.1 - 1.1e-30 106.2 0.0 2.2e-30 105.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 ETS81850.1 - 3.3e-11 43.9 0.0 9.5e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 ETS81850.1 - 7.9e-10 38.6 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETS81850.1 - 9.2e-09 35.8 0.0 1.5e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81850.1 - 1.1e-08 34.7 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS81850.1 - 8e-06 25.8 0.1 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81850.1 - 0.0044 17.4 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81850.1 - 0.0068 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81850.1 - 0.025 15.0 0.0 0.082 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 ETS81850.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2613 PF11021.3 ETS81851.1 - 0.0068 16.0 6.7 0.038 13.7 1.3 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2613) Ank_2 PF12796.2 ETS81853.1 - 1.3e-52 176.0 1.3 9.5e-12 45.0 0.0 9.7 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81853.1 - 8.8e-29 97.8 19.3 0.0043 16.8 0.0 16.0 18 0 0 18 18 18 7 Ankyrin repeat Ank_3 PF13606.1 ETS81853.1 - 1.1e-27 93.3 11.3 0.064 13.5 0.0 14.4 13 1 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 ETS81853.1 - 8.9e-21 73.8 11.2 0.015 15.8 0.0 12.5 10 3 2 12 12 12 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS81853.1 - 3.3e-18 65.2 8.5 0.083 13.1 0.0 11.3 10 3 4 14 14 14 6 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS81853.1 - 4.8e-17 61.5 4.0 1.1e-16 60.4 2.8 1.7 1 0 0 1 1 1 1 Clr5 domain Phage_Gp111 PF07410.6 ETS81854.1 - 0.079 13.1 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein PQ-loop PF04193.9 ETS81856.1 - 0.021 14.3 0.4 0.078 12.5 0.3 1.9 1 0 0 1 1 1 0 PQ loop repeat adh_short PF00106.20 ETS81857.1 - 1.5e-13 51.0 0.3 2.7e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81857.1 - 0.00027 20.6 0.1 0.00046 19.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS81857.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApoLp-III PF07464.6 ETS81857.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FAM60A PF15396.1 ETS81858.1 - 0.18 11.5 5.1 0.38 10.4 3.6 1.5 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.10 ETS81858.1 - 0.55 8.8 6.9 0.034 12.7 1.5 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.7 ETS81858.1 - 3.7 7.3 16.4 1 9.1 7.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 ETS81858.1 - 8.7 3.9 8.7 14 3.2 6.0 1.2 1 0 0 1 1 1 0 Ycf1 F-box-like PF12937.2 ETS81859.1 - 1.5e-07 31.0 0.2 3.8e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS81859.1 - 7.3e-05 22.3 1.3 0.00013 21.4 0.9 1.5 1 0 0 1 1 1 1 F-box domain Cu-oxidase_3 PF07732.10 ETS81860.1 - 1e-37 128.4 1.7 4.5e-37 126.3 0.4 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS81860.1 - 2.6e-21 75.5 11.6 1.3e-17 63.5 0.6 4.2 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS81860.1 - 2.6e-17 63.1 0.0 1e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS81861.1 - 2.4e-20 72.4 0.4 6.6e-20 71.0 0.2 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS81861.1 - 9.4e-16 58.1 0.0 1.6e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS81861.1 - 4.9e-11 42.2 0.1 6.8e-07 28.8 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Mst1_SARAH PF11629.3 ETS81861.1 - 0.16 11.7 0.3 0.37 10.6 0.2 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Zn_clus PF00172.13 ETS81862.1 - 8.3e-09 35.2 14.9 1.4e-08 34.5 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF615 PF04751.9 ETS81862.1 - 0.051 13.2 0.1 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Fungal_trans_2 PF11951.3 ETS81862.1 - 0.056 12.0 1.2 0.095 11.2 0.8 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 ETS81864.1 - 7.9e-58 195.8 0.5 1.1e-57 195.4 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81864.1 - 2.2e-08 33.8 4.3 3.8e-08 33.1 3.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0184 PF03670.8 ETS81864.1 - 0.19 11.8 1.4 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) SCP2 PF02036.12 ETS81865.1 - 1e-23 83.5 0.6 1.2e-23 83.3 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 ETS81865.1 - 3.9e-05 23.6 0.3 7.7e-05 22.6 0.2 1.6 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Ran_BP1 PF00638.13 ETS81866.1 - 5.4e-13 49.0 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 ETS81866.1 - 1.3e-11 44.7 111.2 3.5e-09 36.8 19.8 12.2 2 1 7 9 9 9 3 Nucleoporin FG repeat region CaATP_NAI PF12515.3 ETS81866.1 - 0.15 11.5 0.0 0.59 9.6 0.0 2.0 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Abhydrolase_6 PF12697.2 ETS81867.1 - 3e-28 99.2 0.7 4e-28 98.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81867.1 - 9.4e-12 44.8 0.5 1.4e-11 44.3 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 ETS81868.1 - 2.2e-38 131.9 0.0 1.4e-27 96.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CorA PF01544.13 ETS81870.1 - 8.6e-06 24.9 3.7 1.3e-05 24.4 0.2 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein YopJ PF03421.11 ETS81870.1 - 0.051 13.4 0.3 0.093 12.5 0.2 1.4 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Ank_2 PF12796.2 ETS81871.1 - 2.2e-46 156.0 7.2 2.5e-11 43.7 0.0 5.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS81871.1 - 2e-32 109.3 0.1 3.3e-05 23.4 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 ETS81871.1 - 7.1e-32 108.7 0.2 6.3e-08 32.6 0.0 5.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS81871.1 - 1.8e-29 101.5 0.9 7.3e-07 29.5 0.0 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS81871.1 - 2.5e-27 92.2 0.9 0.00073 19.5 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat PPR_3 PF13812.1 ETS81871.1 - 0.11 12.8 0.1 76 3.9 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain CENP-B_dimeris PF09026.5 ETS81872.1 - 0.12 12.6 2.8 0.31 11.2 2.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNase_NucA_NucB PF14040.1 ETS81873.1 - 2.7e-15 56.4 1.6 5.3e-15 55.5 1.1 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Transketolase_N PF00456.16 ETS81875.1 - 2.3e-151 503.2 0.1 3.2e-151 502.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS81875.1 - 3.7e-46 156.8 0.0 6.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS81875.1 - 6.9e-13 48.6 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain COPIIcoated_ERV PF07970.7 ETS81876.1 - 1.1e-35 123.2 0.3 1.6e-35 122.7 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 ETS81876.1 - 3.5e-20 71.7 0.0 7.3e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Abhydrolase_6 PF12697.2 ETS81877.1 - 1.4e-15 57.8 0.9 2.1e-15 57.2 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS81877.1 - 2.1e-08 34.0 0.7 1.1e-07 31.6 0.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS81877.1 - 0.034 13.7 0.1 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS81877.1 - 0.039 13.7 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative lysophospholipase Herpes_US9 PF06072.6 ETS81878.1 - 0.11 12.3 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Exostosin PF03016.10 ETS81878.1 - 0.18 10.8 0.9 0.25 10.3 0.1 1.5 2 0 0 2 2 2 0 Exostosin family ZZ PF00569.12 ETS81879.1 - 7.7e-20 70.1 60.1 1.3e-06 27.8 6.4 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 ETS81880.1 - 2.6e-28 98.6 2.1 8e-28 97.0 1.5 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 ETS81881.1 - 3.2e-68 230.3 8.3 3.8e-68 230.0 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS81881.1 - 2.2e-10 40.7 0.1 1.4e-09 38.0 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS81881.1 - 5e-06 26.9 1.8 0.034 14.6 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease Aminotran_4 PF01063.14 ETS81882.1 - 1.5e-27 96.5 0.0 2.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 ETS81883.1 - 2.3e-54 180.9 23.0 7.8e-14 51.0 0.7 6.5 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 ETS81883.1 - 3.8e-37 124.3 24.8 1.2e-05 24.6 0.0 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 ETS81883.1 - 7.4e-37 122.3 33.0 2.2e-05 24.0 0.0 11.3 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 ETS81883.1 - 1.9e-23 82.2 25.9 1.5e-07 31.2 0.0 7.5 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 ETS81883.1 - 3.4e-23 81.7 21.4 3e-06 27.7 0.9 7.5 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETS81883.1 - 2.5e-21 74.0 18.6 0.00092 19.2 0.0 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS81883.1 - 1.7e-14 52.4 13.7 0.2 11.5 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS81883.1 - 7e-13 47.3 16.2 0.21 11.4 0.0 8.9 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 ETS81883.1 - 1.7e-10 41.0 23.0 0.00027 21.2 0.5 6.6 6 1 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS81883.1 - 2.2e-10 40.2 16.5 1.5e-05 24.7 1.0 6.7 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS81883.1 - 9.9e-10 38.1 28.7 0.073 13.7 0.8 9.2 6 3 4 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 ETS81883.1 - 2.4e-08 34.0 18.9 0.0019 18.2 0.1 6.1 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 ETS81883.1 - 7.1e-07 28.3 9.9 0.86 8.8 0.0 7.1 7 0 0 7 7 7 2 SHNi-TPR BLVR PF06375.6 ETS81883.1 - 0.0044 16.8 2.1 0.013 15.3 1.5 1.7 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) MAS20 PF02064.10 ETS81883.1 - 0.007 16.2 7.4 7.3 6.5 0.0 4.4 6 0 0 6 6 5 0 MAS20 protein import receptor Glyco_hyd_65N_2 PF14498.1 ETS81883.1 - 0.036 13.7 0.8 0.15 11.7 0.2 2.3 1 1 2 3 3 3 0 Glycosyl hydrolase family 65, N-terminal domain TPR_10 PF13374.1 ETS81883.1 - 0.039 13.9 17.0 1.9 8.5 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat NARP1 PF12569.3 ETS81883.1 - 0.16 10.7 22.3 0.22 10.2 2.0 4.7 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 ETS81883.1 - 0.18 12.3 25.5 6 7.5 0.0 9.1 10 0 0 10 10 9 0 Tetratricopeptide repeat Sel1 PF08238.7 ETS81883.1 - 4.3 8.1 7.5 7.6 7.3 0.1 4.3 4 0 0 4 4 3 0 Sel1 repeat Usp PF00582.21 ETS81883.1 - 4.8 7.3 8.4 15 5.7 1.3 3.4 4 0 0 4 4 3 0 Universal stress protein family AhpC-TSA_2 PF13911.1 ETS81884.1 - 5e-16 58.6 0.0 2e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 ETS81884.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS81884.1 - 0.0071 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin SEC-C PF02810.10 ETS81885.1 - 2.8e-09 36.2 8.5 4.4e-09 35.6 5.9 1.3 1 0 0 1 1 1 1 SEC-C motif dTMP_synthase PF02593.9 ETS81885.1 - 0.00016 21.0 0.7 0.0002 20.8 0.5 1.2 1 0 0 1 1 1 1 Thymidylate synthase UPF1_Zn_bind PF09416.5 ETS81886.1 - 8e-72 239.8 3.5 1.8e-71 238.6 0.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 ETS81886.1 - 7.3e-60 201.7 0.0 1.1e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS81886.1 - 1.5e-54 185.1 0.6 2.3e-54 184.4 0.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS81886.1 - 1.4e-14 53.5 0.1 4.1e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETS81886.1 - 3.6e-12 46.2 0.1 2.7e-10 40.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 ETS81886.1 - 2.2e-06 27.6 0.0 4.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 ETS81886.1 - 1.9e-05 24.2 0.0 0.42 10.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 ETS81886.1 - 4.2e-05 23.2 0.0 8.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 ETS81886.1 - 0.00068 18.7 0.2 0.0055 15.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 ETS81886.1 - 0.0018 17.8 0.1 0.0044 16.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 ETS81886.1 - 0.0018 17.2 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.16 ETS81886.1 - 0.0027 17.0 0.0 0.066 12.5 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 ETS81886.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 ETS81886.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S13_N PF08069.7 ETS81886.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 ETS81886.1 - 0.05 12.7 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 ETS81886.1 - 0.051 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 ETS81886.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS81886.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 ETS81886.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.1 ETS81886.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 ETS81886.1 - 0.12 11.5 0.0 0.3 10.2 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein T2SE PF00437.15 ETS81886.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Brix PF04427.13 ETS81887.1 - 2.9e-46 157.5 0.2 3.7e-46 157.2 0.2 1.1 1 0 0 1 1 1 1 Brix domain Kri1 PF05178.7 ETS81887.1 - 0.02 15.1 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 KRI1-like family DUF429 PF04250.8 ETS81887.1 - 0.033 13.4 0.0 1.3 8.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF429) SNARE PF05739.14 ETS81888.1 - 2.1e-13 49.7 4.6 2.2e-13 49.6 1.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 ETS81888.1 - 4.9e-09 36.2 1.9 4.9e-09 36.2 1.3 2.2 2 0 0 2 2 2 1 Syntaxin PBP1_TM PF14812.1 ETS81888.1 - 0.018 15.3 2.3 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Allexi_40kDa PF05549.6 ETS81888.1 - 0.025 13.8 4.5 0.059 12.6 0.5 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2288 PF10052.4 ETS81888.1 - 0.06 13.0 0.6 0.15 11.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Peptidase_S46 PF10459.4 ETS81888.1 - 0.11 10.8 9.5 0.14 10.5 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF805 PF05656.9 ETS81888.1 - 0.12 12.2 0.2 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) TPPK_C PF12555.3 ETS81888.1 - 0.14 11.9 1.0 0.26 11.0 0.7 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Herpes_US9 PF06072.6 ETS81888.1 - 0.93 9.3 3.2 1.7 8.5 1.2 2.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Syntaxin_2 PF14523.1 ETS81888.1 - 2.5 8.1 11.6 1.9 8.5 3.4 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF1349 PF07081.6 ETS81889.1 - 9.2e-07 28.3 0.0 0.0063 15.8 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) Actino_peptide PF14408.1 ETS81889.1 - 0.04 13.8 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes DUF3355 PF11835.3 ETS81889.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) FUSC_2 PF13515.1 ETS81890.1 - 1.7e-26 92.6 7.0 1.7e-26 92.6 4.8 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 ETS81890.1 - 2.4e-06 26.3 3.8 2.4e-06 26.3 2.6 2.8 3 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 ETS81890.1 - 1.2e-05 25.0 0.3 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 ETS81890.1 - 4.4e-05 22.4 0.5 4.4e-05 22.4 0.3 4.1 3 1 1 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 ETS81890.1 - 0.0001 21.1 23.8 0.0018 16.9 7.9 4.0 3 1 0 3 3 3 2 Aluminium activated malate transporter IpaC_SipC PF09599.5 ETS81890.1 - 0.088 11.8 1.0 0.16 10.9 0.7 1.3 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) DUF3147 PF11345.3 ETS81892.1 - 0.018 15.0 0.5 0.018 15.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) F-box-like PF12937.2 ETS81892.1 - 0.033 13.8 1.4 0.085 12.5 1.0 1.6 1 0 0 1 1 1 0 F-box-like Abi PF02517.11 ETS81892.1 - 0.82 9.8 3.3 0.34 11.0 0.7 1.6 2 0 0 2 2 2 0 CAAX protease self-immunity Tyrosinase PF00264.15 ETS81893.1 - 1.8e-31 110.0 4.3 2.9e-31 109.3 2.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AAT PF03417.11 ETS81894.1 - 4.2e-31 108.1 0.0 5.2e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 ETS81894.1 - 7.4e-06 26.2 0.0 2.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TFIIS_M PF07500.9 ETS81895.1 - 2.2e-28 98.6 1.2 4e-28 97.7 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 ETS81895.1 - 6.3e-18 64.1 7.2 1e-17 63.4 5.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 ETS81895.1 - 1.3e-12 46.9 0.6 2.4e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sgf11 PF08209.6 ETS81895.1 - 3.1 7.2 6.2 5.4 6.4 1.0 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PALP PF00291.20 ETS81896.1 - 2.2e-52 178.2 1.4 2.7e-52 177.9 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 ETS81897.1 - 3e-39 134.9 0.0 4.4e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 ETS81897.1 - 0.00016 20.7 0.0 0.00033 19.6 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase MFS_1 PF07690.11 ETS81898.1 - 5.5e-43 147.0 28.2 5.5e-43 147.0 19.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS81898.1 - 1.6e-17 63.2 8.7 1.6e-17 63.2 6.0 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 ETS81898.1 - 1.7e-09 36.4 3.3 3e-09 35.6 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 ETS81898.1 - 0.0079 14.3 7.6 0.0086 14.1 1.7 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.7 ETS81899.1 - 6.6e-27 93.4 3.2 6.6e-27 93.4 2.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS81899.1 - 1.1e-16 60.5 0.0 2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 ETS81899.1 - 0.011 15.4 0.1 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 S1-like ATP-synt_G PF04718.10 ETS81900.1 - 2.9e-29 101.7 0.6 2.9e-29 101.7 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF959 PF06121.9 ETS81900.1 - 0.068 12.8 2.4 0.36 10.4 0.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) DUF3359 PF11839.3 ETS81900.1 - 0.53 10.6 9.8 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) NYN_YacP PF05991.6 ETS81900.1 - 1.2 8.8 4.4 0.33 10.6 1.1 1.5 2 0 0 2 2 2 0 YacP-like NYN domain DUF4055 PF13264.1 ETS81900.1 - 2.4 8.2 7.6 10 6.2 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) PilJ PF13675.1 ETS81900.1 - 3.4 8.0 7.8 0.72 10.1 1.3 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Methyltransf_23 PF13489.1 ETS81901.1 - 7.3e-16 58.3 0.0 7e-15 55.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS81901.1 - 4.1e-11 43.2 0.0 9.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS81901.1 - 4.6e-10 39.2 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS81901.1 - 7.7e-08 32.8 0.1 1.1e-06 29.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS81901.1 - 3.8e-06 27.1 0.0 9.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS81901.1 - 1.5e-05 25.3 0.0 4.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS81901.1 - 0.00014 21.0 0.0 0.00044 19.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS81901.1 - 0.00026 20.9 0.0 0.00059 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS81901.1 - 0.0014 18.0 0.0 0.0032 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 ETS81901.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 ETS81901.1 - 0.064 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 ETS81901.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 ETS81901.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 ETS81901.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TFIIA PF03153.8 ETS81902.1 - 1.2e-74 252.5 22.5 7.7e-74 249.8 15.6 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETS81902.1 - 0.53 8.4 35.0 0.76 7.9 24.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YL1 PF05764.8 ETS81902.1 - 4.9 6.6 9.8 0.59 9.7 3.0 2.1 3 0 0 3 3 3 0 YL1 nuclear protein HIG_1_N PF04588.8 ETS81903.1 - 4.4e-08 32.7 2.4 4.4e-08 32.7 1.7 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region zf-H2C2_2 PF13465.1 ETS81904.1 - 0.0046 17.1 1.5 0.0046 17.1 1.0 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS81904.1 - 0.013 15.7 15.8 0.11 12.8 1.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS81904.1 - 0.024 14.8 1.9 0.024 14.8 1.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETS81904.1 - 0.041 14.2 21.0 0.37 11.2 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 ETS81904.1 - 0.052 13.4 0.7 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger domain Kelch_4 PF13418.1 ETS81905.1 - 3e-27 94.1 6.5 1.1e-08 34.7 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS81905.1 - 1.9e-22 78.7 5.4 8.5e-07 28.7 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 ETS81905.1 - 2.5e-22 78.0 1.6 9.5e-05 22.4 0.0 4.8 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 ETS81905.1 - 1.3e-20 72.6 0.0 7.2e-05 22.2 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 ETS81905.1 - 1.2e-18 66.6 11.3 2.2e-07 30.8 0.1 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 ETS81905.1 - 8.5e-18 63.3 2.7 0.0016 18.1 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 ETS81905.1 - 5.7e-10 39.1 0.0 9.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 ETS81905.1 - 0.064 12.4 0.0 0.85 8.7 0.0 2.2 1 1 1 2 2 2 0 Cortical protein marker for cell polarity BACK PF07707.10 ETS81905.1 - 0.17 11.7 0.0 0.52 10.1 0.0 1.8 1 1 1 2 2 2 0 BTB And C-terminal Kelch WD40 PF00400.27 ETS81906.1 - 5.9e-24 83.0 16.5 2.9e-06 26.9 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 ETS81906.1 - 1.5e-06 28.0 0.8 0.00023 20.9 0.2 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 ETS81906.1 - 0.4 10.3 7.4 0.11 12.2 0.2 3.4 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term COesterase PF00135.23 ETS81908.1 - 2.9e-91 306.8 0.0 3.2e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS81908.1 - 1.9e-06 27.5 0.1 5e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS81908.1 - 0.0051 16.0 0.7 0.0076 15.4 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS81908.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MBOAT PF03062.14 ETS81909.1 - 4.5e-45 154.1 19.2 4.5e-45 154.1 13.3 2.0 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Cortexin PF11057.3 ETS81909.1 - 0.083 12.4 0.3 0.81 9.3 0.0 2.6 2 1 0 2 2 2 0 Cortexin of kidney MBOAT_2 PF13813.1 ETS81909.1 - 0.21 11.7 6.4 0.29 11.2 3.5 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Baculo_PEP_C PF04513.7 ETS81911.1 - 0.058 13.2 0.7 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.2 ETS81912.1 - 1.4e-13 50.3 0.3 3.4e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS81912.1 - 1.7e-05 24.3 0.2 4.1e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 ETS81912.1 - 0.025 14.4 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 ETS81912.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CrtC PF07143.6 ETS81913.1 - 8.1e-07 28.6 0.9 0.0068 15.7 0.0 2.0 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) Fungal_trans PF04082.13 ETS81914.1 - 8.8e-22 77.2 0.4 1.5e-21 76.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS81914.1 - 6.9e-11 41.8 12.8 1.1e-10 41.2 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain priB_priC PF07445.7 ETS81914.1 - 0.046 13.1 0.5 0.56 9.6 0.6 2.3 2 0 0 2 2 2 0 Primosomal replication protein priB and priC Mito_carr PF00153.22 ETS81915.1 - 7.1e-63 208.3 1.8 6.6e-21 73.8 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.14 ETS81916.1 - 6.9e-25 87.2 0.2 4.1e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.6 ETS81917.1 - 1e-155 518.7 0.0 1.3e-155 518.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SET PF00856.23 ETS81918.1 - 6.5e-09 36.2 0.0 2.2e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 SET domain SRF-TF PF00319.13 ETS81919.1 - 4.9e-23 80.1 0.2 7.6e-23 79.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.3 ETS81920.1 - 1.6e-143 478.4 5.6 1.8e-89 300.2 1.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 ETS81920.1 - 0.0012 18.4 1.0 0.0028 17.3 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 ETS81920.1 - 0.014 15.2 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2709 PF10915.3 ETS81920.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) D-ser_dehydrat PF14031.1 ETS81921.1 - 7.9e-23 80.4 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 ETS81921.1 - 3.6e-17 62.6 0.0 5.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Syja_N PF02383.13 ETS81923.1 - 3.7e-84 282.2 0.0 4.5e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mitofilin PF09731.4 ETS81924.1 - 8.1e-154 513.4 10.7 1.2e-153 512.8 7.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ras PF00071.17 ETS81924.1 - 6.2e-57 191.4 0.1 1.4e-56 190.3 0.1 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS81924.1 - 3.8e-18 66.1 0.1 8.3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS81924.1 - 7.1e-14 51.4 0.6 1.2e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS81924.1 - 8.3e-07 28.6 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS81924.1 - 1.4e-06 27.5 0.0 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS81924.1 - 8.1e-05 22.5 0.0 0.00026 20.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS81924.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cas_DxTHG PF09455.5 ETS81924.1 - 0.53 9.3 5.8 1.1 8.2 3.4 1.8 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family LUC7 PF03194.10 ETS81924.1 - 1.6 8.1 16.1 0.52 9.7 6.2 2.4 1 1 1 2 2 2 0 LUC7 N_terminus PIG-P PF08510.7 ETS81925.1 - 1.3e-44 150.8 0.7 1.7e-44 150.5 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.1 ETS81925.1 - 0.022 14.1 1.1 0.035 13.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4118 PF13493.1 ETS81925.1 - 0.16 12.1 10.4 0.33 11.1 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) DUF485 PF04341.7 ETS81925.1 - 5 6.9 8.5 0.27 10.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Actin PF00022.14 ETS81926.1 - 1e-136 455.5 0.0 1.1e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETS81926.1 - 7.3e-07 28.0 0.2 0.016 13.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF423 PF04241.10 ETS81927.1 - 2.5e-28 97.8 1.0 4e-28 97.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2721 PF11026.3 ETS81927.1 - 0.0049 16.5 0.4 0.0049 16.5 0.3 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2721) DUF1469 PF07332.6 ETS81927.1 - 2 8.1 10.5 4.4 7.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Memo PF01875.12 ETS81928.1 - 3.3e-75 252.4 0.0 3.9e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.13 ETS81928.1 - 0.027 13.4 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Kinesin PF00225.18 ETS81929.1 - 4.3e-108 360.9 1.0 8.6e-108 359.9 0.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 ETS81929.1 - 1.7e-06 28.2 0.0 1.7e-06 28.2 0.0 4.9 4 2 1 5 5 5 1 Kinesin-associated microtubule-binding Prominin PF05478.6 ETS81929.1 - 0.27 8.7 32.3 0.005 14.4 6.8 3.7 1 1 3 4 4 4 0 Prominin DUF479 PF04336.7 ETS81929.1 - 1.7 8.7 4.8 2.6 8.2 0.3 3.6 3 2 1 4 4 4 0 Protein of unknown function, DUF479 CK1gamma_C PF12605.3 ETS81929.1 - 2 9.0 8.7 1.8 9.1 0.6 3.3 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal Baculo_PEP_C PF04513.7 ETS81929.1 - 7.9 6.2 24.3 0.67 9.7 0.1 6.1 2 1 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0183 PF03676.9 ETS81930.1 - 6.4e-40 136.9 0.0 1.3e-13 50.2 0.0 5.0 5 0 0 5 5 5 5 Uncharacterised protein family (UPF0183) DUF2463 PF09591.5 ETS81930.1 - 0.22 11.1 0.1 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Histidinol_dh PF00815.15 ETS81931.1 - 3.5e-179 595.7 3.9 4.7e-179 595.3 2.7 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 ETS81931.1 - 6.7e-25 86.5 0.1 1.3e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 ETS81931.1 - 2.9e-10 40.2 1.1 6.3e-10 39.1 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 ETS81932.1 - 1.4e-24 86.2 0.0 4.1e-23 81.5 0.0 2.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.8 ETS81933.1 - 6.1e-71 237.0 0.0 1e-70 236.3 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 ETS81933.1 - 3.9e-40 135.9 0.0 5.5e-39 132.2 0.0 2.4 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 ETS81933.1 - 0.00039 19.8 0.0 0.17 11.2 0.0 3.1 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) MFS_1 PF07690.11 ETS81935.1 - 7.3e-26 90.7 61.1 1.4e-25 89.8 40.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.16 ETS81935.1 - 0.58 10.0 4.6 6.9 6.6 0.5 3.9 3 0 0 3 3 3 0 Gram positive anchor fn3 PF00041.16 ETS81936.1 - 2.4e-06 27.5 0.0 7.4e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain AAA_13 PF13166.1 ETS81936.1 - 0.031 12.7 21.0 0.0072 14.8 1.3 2.4 1 1 1 2 2 2 0 AAA domain Sugarporin_N PF11471.3 ETS81936.1 - 3.5 7.3 12.4 5.9 6.6 1.0 2.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF948 PF06103.6 ETS81936.1 - 8.6 6.2 6.1 38 4.2 1.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cmc1 PF08583.5 ETS81937.1 - 1.6e-14 53.4 8.9 4e-14 52.1 6.2 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1005 PF06219.7 ETS81937.1 - 0.00038 19.2 1.3 0.00049 18.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1005) CHCH PF06747.8 ETS81937.1 - 0.018 14.9 1.1 0.048 13.5 0.7 1.7 1 1 1 2 2 2 0 CHCH domain DUF559 PF04480.7 ETS81937.1 - 0.027 14.1 0.3 0.062 12.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF559) MFS_1 PF07690.11 ETS81940.1 - 4.9e-35 120.8 31.6 1e-23 83.6 10.8 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 ETS81940.1 - 0.018 13.5 38.9 0.13 10.6 12.8 2.7 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Adeno_E3 PF06040.6 ETS81940.1 - 0.12 12.3 3.7 0.087 12.7 0.3 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF2615 PF11027.3 ETS81940.1 - 0.2 11.5 0.9 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF2512 PF10710.4 ETS81940.1 - 0.82 9.1 9.1 0.47 9.9 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) F-box PF00646.28 ETS81941.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain SET PF00856.23 ETS81942.1 - 3.1e-10 40.5 0.4 3.1e-10 40.5 0.3 2.7 3 1 0 3 3 3 1 SET domain Nop14 PF04147.7 ETS81942.1 - 4.9 4.9 9.7 6.2 4.6 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family APC_CDC26 PF10471.4 ETS81944.1 - 3.8e-10 40.3 1.3 3.8e-10 40.3 0.9 4.7 4 1 0 4 4 4 1 Anaphase-promoting complex APC subunit 1 Spt5_N PF11942.3 ETS81944.1 - 0.0043 17.6 21.3 0.068 13.7 8.0 2.4 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 ETS81944.1 - 0.081 10.9 17.9 0.018 13.1 6.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Band_3_cyto PF07565.8 ETS81944.1 - 1.1 8.7 6.4 7.8 5.9 0.9 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Nop53 PF07767.6 ETS81944.1 - 7.5 5.4 20.0 0.08 11.9 3.9 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Peptidase_M1 PF01433.15 ETS81945.1 - 7.4e-11 41.7 0.0 0.0015 17.7 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 SAS4 PF15460.1 ETS81946.1 - 1.1e-32 111.8 0.1 3.4e-32 110.3 0.1 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 BTV_NS2 PF04514.7 ETS81946.1 - 0.56 9.0 7.8 1.5 7.5 5.4 1.8 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Amidase PF01425.16 ETS81947.1 - 1.3e-34 119.8 0.6 2e-34 119.2 0.4 1.2 1 0 0 1 1 1 1 Amidase IQ PF00612.22 ETS81948.1 - 0.00015 21.0 1.0 0.00051 19.4 0.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif AA_permease_2 PF13520.1 ETS81949.1 - 5.7e-48 163.4 51.8 7.2e-48 163.1 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS81949.1 - 2.2e-27 95.5 44.9 3.3e-27 94.9 31.1 1.1 1 0 0 1 1 1 1 Amino acid permease PufQ PF05398.6 ETS81949.1 - 0.77 9.8 0.0 0.77 9.8 0.0 3.4 4 0 0 4 4 4 0 PufQ cytochrome subunit RskA PF10099.4 ETS81950.1 - 0.49 10.0 5.7 0.084 12.6 0.5 2.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA ABC_membrane_2 PF06472.10 ETS81951.1 - 2.4e-99 332.0 0.2 1.4e-97 326.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 ETS81951.1 - 2.6e-15 56.8 0.0 6.8e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 ETS81951.1 - 0.0035 17.6 1.3 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS81951.1 - 0.022 14.7 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 ETS81951.1 - 0.025 15.3 0.1 0.12 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETS81951.1 - 0.033 13.7 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 ETS81951.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 ETS81951.1 - 0.048 12.8 0.1 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.1 ETS81951.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 ETS81951.1 - 0.094 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 ETS81951.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS81951.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain End3 PF12761.2 ETS81951.1 - 0.18 11.4 1.6 0.38 10.3 1.1 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 NIF PF03031.13 ETS81952.1 - 1.5e-51 174.2 0.5 2e-51 173.8 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CPSF_A PF03178.10 ETS81953.1 - 1.7e-79 267.2 0.0 3.6e-79 266.1 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 ETS81953.1 - 0.0011 17.2 0.0 0.012 13.8 0.0 2.5 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PBP1_TM PF14812.1 ETS81953.1 - 1 9.6 5.7 0.77 10.1 0.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box PF00646.28 ETS81954.1 - 0.019 14.6 0.3 0.074 12.7 0.0 2.1 2 0 0 2 2 2 0 F-box domain RNA_pol_Rpb1_1 PF04997.7 ETS81956.1 - 7e-116 387.1 0.1 1.1e-115 386.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 ETS81956.1 - 5.6e-101 337.4 0.0 2.1e-100 335.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETS81956.1 - 2e-69 232.8 0.0 4.2e-69 231.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 ETS81956.1 - 3.7e-51 173.5 1.8 2.7e-50 170.7 0.8 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 ETS81956.1 - 2.9e-44 150.5 0.0 7.4e-44 149.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 ETS81956.1 - 3e-38 130.5 3.3 6.8e-38 129.4 1.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 ETS81956.1 - 9.6e-37 125.0 0.1 2.3e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 ETS81956.1 - 0.06 13.4 187.4 0.095 12.8 6.4 13.4 10 3 5 15 15 15 0 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 ETS81957.1 - 8e-13 47.7 4.4 7.8e-05 22.4 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 ETS81957.1 - 1.3e-05 24.9 0.2 0.045 13.4 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 ETS81957.1 - 0.00052 19.5 0.7 0.0027 17.1 0.1 2.0 2 1 0 2 2 2 1 PQQ-like domain B_lectin PF01453.19 ETS81957.1 - 0.066 13.1 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 D-mannose binding lectin Thg1C PF14413.1 ETS81958.1 - 1.5e-51 173.1 0.2 2e-51 172.7 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 ETS81958.1 - 1.4e-46 157.4 0.0 2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase SIM_C PF06621.7 ETS81959.1 - 0.087 12.3 6.4 0.12 11.9 4.4 1.2 1 0 0 1 1 1 0 Single-minded protein C-terminus DUF4407 PF14362.1 ETS81959.1 - 0.64 8.9 10.1 0.73 8.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 ETS81959.1 - 2.2 8.1 14.3 3.2 7.5 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 ETS81959.1 - 7.4 5.8 16.5 10 5.4 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CytochromB561_N PF09786.4 ETS81960.1 - 0.0017 16.8 0.2 0.0023 16.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal UDG PF03167.14 ETS81962.1 - 3.2e-22 78.6 0.0 4.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.13 ETS81963.1 - 2.8e-44 151.2 0.0 8.1e-43 146.4 0.0 2.1 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 ETS81963.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Ribophorin_II PF05817.9 ETS81964.1 - 2.8e-27 95.2 0.1 3.2e-27 95.0 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II YecR PF13992.1 ETS81965.1 - 0.11 12.6 0.6 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 YecR-like lipoprotein DUF1656 PF07869.7 ETS81966.1 - 0.39 10.5 3.7 1 9.2 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CENP-B_dimeris PF09026.5 ETS81966.1 - 0.42 10.8 7.8 0.82 9.9 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Bromodomain PF00439.20 ETS81967.1 - 3.4e-27 94.1 0.8 8e-27 92.9 0.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 ETS81967.1 - 2.5e-09 37.1 0.6 4.3e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS81967.1 - 4.9e-09 36.1 0.1 1.1e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family UPF0197 PF05251.7 ETS81968.1 - 0.011 16.0 4.3 0.019 15.2 3.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF2627 PF11118.3 ETS81968.1 - 0.017 15.2 2.3 0.017 15.2 1.6 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2627) Rad1 PF02144.11 ETS81969.1 - 5.5e-87 291.0 0.0 6.3e-87 290.8 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PX PF00787.19 ETS81973.1 - 2.9e-20 72.1 0.0 4.8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Hint PF01079.15 ETS81973.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Hint module Mpv17_PMP22 PF04117.7 ETS81974.1 - 3.7e-27 93.7 0.7 6.7e-27 92.9 0.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M28 PF04389.12 ETS81975.1 - 2.7e-39 134.7 0.0 3.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 ETS81975.1 - 1.8 8.4 5.3 0.45 10.4 0.6 2.2 2 1 0 3 3 3 0 Primase C terminal 2 (PriCT-2) CDP-OH_P_transf PF01066.16 ETS81976.1 - 5.4e-18 65.1 1.7 5.4e-18 65.1 1.2 2.6 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_43 PF04616.9 ETS81978.1 - 4.6e-34 117.8 1.2 6.2e-34 117.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DCR PF14047.1 ETS81978.1 - 0.073 13.3 0.1 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Dppa2/4 conserved region LSM PF01423.17 ETS81979.1 - 1.2e-10 40.8 0.0 1.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS81979.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain XPG_N PF00752.12 ETS81980.1 - 1e-33 115.6 0.0 2.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 ETS81980.1 - 1.7e-26 92.0 0.0 4.6e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 ETS81980.1 - 0.0023 17.3 2.5 0.021 14.3 1.7 2.9 1 0 0 1 1 1 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 ETS81980.1 - 0.018 15.2 0.0 0.088 13.0 0.0 2.2 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CTV_P6 PF06706.6 ETS81982.1 - 0.0042 16.5 1.8 0.021 14.3 1.3 2.2 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein DUF202 PF02656.10 ETS81982.1 - 5.5 7.2 8.0 8.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Aldedh PF00171.17 ETS81983.1 - 3.5e-132 441.0 0.2 4.2e-132 440.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PsbY PF06298.6 ETS81983.1 - 0.081 12.4 0.4 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) adh_short_C2 PF13561.1 ETS81985.1 - 3.9e-28 98.8 0.0 5.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS81985.1 - 3.8e-24 85.4 3.5 5.8e-24 84.8 2.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS81985.1 - 1.5e-13 50.8 1.9 2.4e-13 50.1 1.3 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_43 PF04616.9 ETS81986.1 - 5e-53 180.0 1.1 6.8e-53 179.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1467 PF07330.7 ETS81986.1 - 0.13 12.0 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) LMBR1 PF04791.11 ETS81987.1 - 6.8e-15 54.6 1.2 6.8e-15 54.6 0.8 2.3 1 1 1 2 2 2 1 LMBR1-like membrane protein Arc_PepC_II PF06847.6 ETS81987.1 - 0.31 11.5 2.1 2 8.8 0.9 2.4 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II UPF0233 PF06781.7 ETS81987.1 - 7.1 6.3 7.1 0.68 9.5 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) HSP70 PF00012.15 ETS81988.1 - 1e-231 770.0 7.3 1.1e-231 769.9 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS81988.1 - 2.1e-16 59.4 0.2 3.7e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 ETS81988.1 - 0.00042 19.9 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 ETS81988.1 - 0.11 12.3 2.9 4.7 7.0 0.7 3.7 2 1 0 2 2 2 0 Cell division protein FtsA Bromodomain PF00439.20 ETS81989.1 - 1.9e-33 114.2 0.2 1.3e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Ribosomal_60s PF00428.14 ETS81989.1 - 0.00058 20.2 5.1 0.00058 20.2 3.5 3.7 3 1 1 4 4 3 1 60s Acidic ribosomal protein SDA1 PF05285.7 ETS81989.1 - 0.0045 16.3 13.8 0.0071 15.6 9.6 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 ETS81989.1 - 0.0058 14.6 18.7 0.011 13.6 13.0 1.4 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.7 ETS81989.1 - 0.023 13.8 18.7 0.039 13.0 12.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 ETS81989.1 - 0.038 13.0 13.4 0.067 12.2 9.3 1.4 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 ETS81989.1 - 0.064 12.6 7.9 0.12 11.8 5.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 ETS81989.1 - 0.18 11.1 13.3 0.31 10.3 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 ETS81989.1 - 1.1 8.7 8.7 2.4 7.6 6.1 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4407 PF14362.1 ETS81989.1 - 1.1 8.1 5.1 1.8 7.4 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Daxx PF03344.10 ETS81989.1 - 1.7 7.0 24.3 0.041 12.3 12.3 1.5 2 0 0 2 2 2 0 Daxx Family TFIIA PF03153.8 ETS81989.1 - 2.1 8.1 22.5 0.31 10.8 7.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit YL1 PF05764.8 ETS81989.1 - 4.2 6.9 22.7 9.1 5.8 15.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CKS PF01111.14 ETS81990.1 - 1.9e-33 114.0 0.6 2.5e-33 113.7 0.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 ETS81991.1 - 5e-134 446.8 0.0 7.1e-134 446.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.4 ETS81992.1 - 8.1e-64 214.9 0.0 1.8e-63 213.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein FTA2 PF13095.1 ETS81993.1 - 2.4e-22 79.5 0.0 3.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pal1 PF08316.6 ETS81994.1 - 1.7e-09 38.2 0.1 2.5e-09 37.7 0.1 1.5 1 1 0 1 1 1 1 Pal1 cell morphology protein MDH PF02315.11 ETS81994.1 - 0.1 12.5 0.5 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Pil1 PF13805.1 ETS81995.1 - 9.9e-154 510.2 0.8 1.2e-153 509.9 0.6 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 ETS81995.1 - 0.1 11.9 3.6 0.26 10.6 2.5 1.7 1 1 0 1 1 1 0 FAM92 protein SET PF00856.23 ETS81996.1 - 1.7e-21 77.1 0.8 6.6e-21 75.3 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF4179 PF13786.1 ETS81999.1 - 0.1 12.8 0.4 5.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2140 PF09911.4 ETS81999.1 - 0.46 9.6 5.6 6.4 5.9 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) FAM165 PF14981.1 ETS81999.1 - 0.84 9.1 0.0 0.84 9.1 0.0 2.6 3 0 0 3 3 3 0 FAM165 family PPP4R2 PF09184.6 ETS82000.1 - 3.7e-10 39.8 12.9 4.7e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 PPP4R2 SbcCD_C PF13558.1 ETS82001.1 - 2.1e-11 43.5 0.0 7.5e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 ETS82001.1 - 1.4e-10 40.2 117.9 2.5e-05 22.9 5.9 6.1 3 2 3 6 6 6 4 AAA domain AAA_21 PF13304.1 ETS82001.1 - 1.1e-09 38.6 7.6 3.8e-06 27.0 0.3 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETS82001.1 - 5.4e-09 36.6 116.2 1.6e+02 2.5 0.8 7.2 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 ETS82001.1 - 7.5e-07 28.6 36.4 1.5e-05 24.3 25.2 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 ETS82001.1 - 2.3e-05 23.6 0.0 2.3e-05 23.6 0.0 6.5 4 3 0 6 6 6 2 AAA ATPase domain AAA_29 PF13555.1 ETS82001.1 - 0.0019 17.7 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS82001.1 - 0.073 13.3 0.0 0.073 13.3 0.0 6.7 3 2 0 4 4 4 0 ABC transporter AAA_16 PF13191.1 ETS82001.1 - 0.26 11.2 0.0 0.26 11.2 0.0 4.6 3 1 1 4 4 4 0 AAA ATPase domain GATA PF00320.22 ETS82002.1 - 4.7e-16 57.8 4.9 8.9e-16 56.9 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 ETS82002.1 - 1.2e-10 41.3 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 ETS82002.1 - 6.7e-09 35.5 0.1 2.8e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 ETS82002.1 - 1.3e-07 31.9 0.1 4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 ETS82002.1 - 7.8e-07 29.0 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 ETS82002.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold APC2 PF08672.6 ETS82002.1 - 0.077 13.2 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 TF_Zn_Ribbon PF08271.7 ETS82002.1 - 0.14 11.5 0.6 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 ETS82002.1 - 2.3 8.0 4.9 0.55 10.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ECH PF00378.15 ETS82003.1 - 3.4e-37 127.8 0.0 9.9e-37 126.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acetyltransf_1 PF00583.19 ETS82005.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 ETS82005.1 - 7.8e-10 39.0 0.1 1.1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS82005.1 - 2.5e-08 34.0 0.2 3.9e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS82005.1 - 0.00034 20.7 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS82005.1 - 0.0029 17.3 0.0 0.013 15.2 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETS82005.1 - 0.0045 16.8 0.0 0.0066 16.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_60s PF00428.14 ETS82005.1 - 0.03 14.7 0.1 0.052 13.9 0.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNase_P_p30 PF01876.11 ETS82006.1 - 2.2e-45 153.5 0.0 3.2e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF3277 PF11681.3 ETS82007.1 - 0.042 13.3 0.5 1.1 8.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3277) GRP PF07172.6 ETS82008.1 - 4.2 7.9 8.9 0.57 10.6 3.3 1.6 2 0 0 2 2 2 0 Glycine rich protein family Sugar_tr PF00083.19 ETS82010.1 - 3.2e-92 309.4 22.7 3.7e-92 309.2 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82010.1 - 4.4e-11 42.1 39.7 4.1e-08 32.3 5.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 ETS82011.1 - 0.081 12.1 6.3 0.14 11.3 4.4 1.5 1 1 0 1 1 1 0 Tetraspanin family MARVEL PF01284.18 ETS82011.1 - 5.2 6.8 13.8 11 5.8 9.6 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4448 PF14610.1 ETS82012.1 - 5.6e-45 153.1 0.6 8.1e-45 152.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1776 PF08643.5 ETS82013.1 - 1.9e-110 368.7 0.0 2.3e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-CCCH PF00642.19 ETS82014.1 - 2.2e-23 81.3 27.5 8.2e-07 28.5 0.2 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS82014.1 - 0.022 14.7 0.2 0.022 14.7 0.2 5.3 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type FXR1P_C PF12235.3 ETS82014.1 - 1.2 9.2 12.2 2 8.5 8.4 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Glyco_hydro_31 PF01055.21 ETS82015.1 - 2e-157 524.5 5.6 2.5e-157 524.2 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Asp_Glu_race PF01177.17 ETS82016.1 - 1.5e-28 100.2 0.2 1.7e-28 99.9 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HET PF06985.6 ETS82017.1 - 1.9e-33 115.5 0.1 3.1e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.16 ETS82018.1 - 4.1e-19 68.5 0.0 4.8e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_31 PF13847.1 ETS82020.1 - 8.8e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS82020.1 - 4.3e-13 49.5 0.1 3.3e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS82020.1 - 1e-11 45.1 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82020.1 - 5.2e-11 43.1 0.0 1e-10 42.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 ETS82020.1 - 2.1e-10 40.2 0.0 3.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS82020.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS82020.1 - 4.1e-08 33.1 0.0 1.6e-07 31.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS82020.1 - 1.1e-07 31.8 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS82020.1 - 5.6e-05 22.8 0.0 8.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS82020.1 - 6.9e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 ETS82020.1 - 0.00013 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 ETS82020.1 - 0.0026 16.6 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 ETS82020.1 - 0.0047 15.9 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS82020.1 - 0.0064 15.6 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 ETS82020.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.15 ETS82020.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Amidase PF01425.16 ETS82021.1 - 3.5e-87 293.0 0.0 4.6e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.22 ETS82022.1 - 3.1e-07 30.2 0.1 6.3e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily ubiquitin PF00240.18 ETS82023.1 - 2.5e-18 65.2 0.0 4.5e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 ETS82023.1 - 1.8e-09 37.1 2.5 3.5e-08 33.0 0.0 2.9 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 ETS82023.1 - 0.00048 19.7 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 ETS82023.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBACT PF02134.16 ETS82023.1 - 0.092 12.3 0.0 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein RicinB_lectin_2 PF14200.1 ETS82023.1 - 0.098 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF2407 PF10302.4 ETS82023.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ADH_zinc_N PF00107.21 ETS82024.1 - 3.8e-34 117.0 0.4 5.9e-34 116.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS82024.1 - 2.1e-10 41.5 0.3 4.4e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS82024.1 - 9.6e-06 25.3 0.0 2.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 ETS82024.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 ETS82024.1 - 0.025 14.1 0.2 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1254 PF06863.7 ETS82024.1 - 0.13 12.1 0.3 0.81 9.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1254) FAP PF07174.6 ETS82025.1 - 0.016 14.5 10.3 0.017 14.4 7.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4017 PF13209.1 ETS82025.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) p450 PF00067.17 ETS82026.1 - 5.5e-56 190.0 0.0 7.1e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.1 ETS82027.1 - 1.2e-14 54.6 1.8 8.1e-14 51.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS82027.1 - 1.3e-12 47.7 0.1 3.7e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 ETS82027.1 - 2.2e-05 23.8 0.3 0.00017 20.9 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 21 Myb_DNA-bind_6 PF13921.1 ETS82028.1 - 0.057 13.5 0.1 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ank_2 PF12796.2 ETS82029.1 - 3e-54 181.3 20.5 9.6e-14 51.5 1.9 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82029.1 - 1.6e-42 141.2 27.8 1.2e-06 28.0 0.2 11.5 10 1 1 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 ETS82029.1 - 1.1e-33 114.4 16.4 3.6e-07 30.2 0.9 10.3 3 2 7 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82029.1 - 3.9e-33 110.1 5.2 0.0015 18.5 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 ETS82029.1 - 1.2e-29 102.1 11.7 5.5e-07 29.9 0.2 8.6 4 2 6 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.7 ETS82029.1 - 5.9e-11 42.2 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS82029.1 - 0.00031 20.8 0.1 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS82029.1 - 0.0098 15.8 0.0 0.0098 15.8 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_26 PF13500.1 ETS82029.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2384 PF09722.5 ETS82029.1 - 1.6 8.6 10.0 27 4.7 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) zf-RING_2 PF13639.1 ETS82030.1 - 2.9e-14 52.5 1.8 6e-14 51.5 1.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS82030.1 - 1.5e-07 30.9 0.4 3.4e-07 29.8 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS82030.1 - 2.9e-07 30.4 1.8 8.1e-07 29.0 1.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETS82030.1 - 2.9e-07 30.3 1.0 5.7e-07 29.4 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS82030.1 - 0.00012 21.7 0.4 0.00024 20.7 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS82030.1 - 0.0017 17.9 0.3 0.0037 16.8 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 ETS82030.1 - 0.0049 16.7 2.1 0.015 15.2 0.8 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 ETS82030.1 - 0.0061 16.2 0.7 0.012 15.2 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS82030.1 - 0.028 14.2 1.4 0.13 12.1 1.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 ETS82030.1 - 0.03 14.1 0.7 0.08 12.8 0.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 ETS82030.1 - 0.071 12.8 0.7 0.15 11.8 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.2 ETS82030.1 - 0.17 11.9 3.0 2.2 8.3 1.8 2.4 1 1 1 2 2 2 0 RING-variant domain FAD_binding_3 PF01494.14 ETS82031.1 - 1.4e-20 73.6 0.1 2.6e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS82031.1 - 3.9e-07 29.2 0.0 2.1e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS82031.1 - 6.1e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS82031.1 - 0.00017 20.5 0.1 0.00061 18.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS82031.1 - 0.00025 20.1 0.1 0.0011 17.9 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS82031.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS82031.1 - 0.0016 18.5 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS82031.1 - 0.0029 17.9 0.1 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS82031.1 - 0.0069 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 ETS82031.1 - 0.056 12.5 0.0 0.84 8.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PilO PF04350.8 ETS82031.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO TrkA_N PF02254.13 ETS82031.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Aldolase_II PF00596.16 ETS82032.1 - 1.2e-26 93.4 0.8 1.6e-26 93.0 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1115 PF06544.7 ETS82034.1 - 1.8e-19 69.7 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1691 PF07950.6 ETS82035.1 - 4.3e-39 132.8 5.9 3e-25 88.2 1.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 ETS82036.1 - 1.1e-06 28.6 2.6 1.8e-06 27.9 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS82036.1 - 0.00016 21.7 0.6 0.00027 21.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 ETS82036.1 - 0.0061 16.2 0.8 0.0099 15.5 0.6 1.3 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.1 ETS82036.1 - 0.0078 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS82036.1 - 0.017 15.4 0.8 0.03 14.6 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ETS82036.1 - 0.057 13.5 0.5 0.089 12.9 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) 4HBT_3 PF13622.1 ETS82037.1 - 3.9e-39 134.9 0.2 4.7e-39 134.6 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.6 ETS82038.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AP_endonuc_2 PF01261.19 ETS82040.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Cupin_2 PF07883.6 ETS82042.1 - 1.3e-07 30.9 0.0 2.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS82042.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 ETS82042.1 - 0.003 16.9 0.0 0.0069 15.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Romo1 PF10247.4 ETS82043.1 - 0.00015 21.9 0.7 0.11 12.7 0.0 2.4 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.6 ETS82043.1 - 0.11 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) ATPase_gene1 PF09527.5 ETS82043.1 - 6.8 6.5 11.0 0.37 10.6 0.3 2.7 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) RTA1 PF04479.8 ETS82045.1 - 2.6e-10 40.1 6.0 1.1e-09 38.1 4.1 1.9 1 1 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.1 ETS82045.1 - 0.0078 16.2 5.6 0.014 15.4 1.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3995) PMP1_2 PF08114.6 ETS82045.1 - 0.025 14.0 0.8 0.072 12.5 0.6 1.8 1 0 0 1 1 1 0 ATPase proteolipid family DUF4131 PF13567.1 ETS82045.1 - 0.61 9.4 3.8 5.5 6.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 ETS82046.1 - 1.9e-22 79.3 0.2 3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82046.1 - 0.0033 17.2 7.8 0.0059 16.4 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DehI PF10778.4 ETS82046.1 - 0.099 12.1 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI bZIP_2 PF07716.10 ETS82047.1 - 2.6e-07 30.3 18.9 5.5e-07 29.3 13.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS82047.1 - 5.7e-05 22.9 21.0 7.8e-05 22.5 14.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor DUF3450 PF11932.3 ETS82047.1 - 0.007 15.6 3.2 0.011 15.0 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) bZIP_Maf PF03131.12 ETS82047.1 - 0.015 15.5 13.1 0.031 14.5 9.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Gcd10p PF04189.8 ETS82047.1 - 0.14 11.2 5.1 0.26 10.3 3.5 1.4 1 0 0 1 1 1 0 Gcd10p family NYD-SP28_assoc PF14775.1 ETS82047.1 - 0.18 11.5 2.1 0.41 10.3 1.4 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain APG6 PF04111.7 ETS82047.1 - 0.79 8.7 8.7 1.2 8.1 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 ETS82047.1 - 1.3 8.5 4.9 2.5 7.6 3.4 1.4 1 0 0 1 1 1 0 Septum formation initiator CDC45 PF02724.9 ETS82048.1 - 0.0024 15.9 2.5 0.0025 15.9 1.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 ETS82048.1 - 0.023 13.1 3.5 0.025 13.1 2.4 1.1 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 ETS82048.1 - 0.066 11.5 1.7 0.049 11.9 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 ETS82048.1 - 0.24 11.4 3.4 0.33 10.9 2.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 ETS82048.1 - 2.4 7.8 6.1 4.2 7.0 4.2 1.4 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 ETS82048.1 - 3 7.1 10.1 3.9 6.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 ETS82048.1 - 3.9 5.2 12.5 4.9 4.9 8.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2413 PF10310.4 ETS82048.1 - 5.5 5.6 9.8 6.7 5.4 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Filament PF00038.16 ETS82049.1 - 0.0034 16.9 14.0 0.0064 16.0 9.7 1.6 1 1 0 1 1 1 1 Intermediate filament protein FlxA PF14282.1 ETS82049.1 - 0.0059 16.5 3.8 0.081 12.8 2.3 2.5 2 0 0 2 2 2 1 FlxA-like protein IFT57 PF10498.4 ETS82049.1 - 0.0095 14.7 6.2 0.013 14.2 4.3 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CENP-Q PF13094.1 ETS82049.1 - 0.014 15.4 21.3 0.038 14.0 14.5 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 ETS82049.1 - 0.025 13.2 12.9 0.04 12.5 9.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.1 ETS82049.1 - 0.025 14.0 15.3 0.46 9.9 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 ETS82049.1 - 0.029 13.3 18.9 0.028 13.3 10.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 ETS82049.1 - 0.038 14.1 6.1 0.43 10.7 3.5 2.3 2 0 0 2 2 2 0 Syntaxin AAA_27 PF13514.1 ETS82049.1 - 0.051 11.2 18.5 0.068 10.8 12.8 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.6 ETS82049.1 - 0.052 13.3 17.7 0.37 10.5 5.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 ETS82049.1 - 0.055 13.6 0.8 0.055 13.6 0.5 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4610 PF15384.1 ETS82049.1 - 0.057 12.9 0.4 0.057 12.9 0.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4610) Cas_DxTHG PF09455.5 ETS82049.1 - 0.062 12.4 1.2 0.072 12.2 0.9 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family ER-remodelling PF14755.1 ETS82049.1 - 0.064 13.3 4.0 0.11 12.6 0.2 2.5 3 0 0 3 3 2 0 Intracellular membrane remodeller Bacillus_HBL PF05791.6 ETS82049.1 - 0.066 12.5 2.9 0.16 11.3 0.7 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4140 PF13600.1 ETS82049.1 - 0.067 13.6 17.4 0.19 12.2 1.3 2.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 ETS82049.1 - 0.073 13.3 2.2 5.3 7.3 0.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 ETS82049.1 - 0.076 12.5 19.7 1 8.8 12.0 2.3 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 ETS82049.1 - 0.13 10.7 10.4 0.21 9.9 7.2 1.3 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 ETS82049.1 - 0.15 11.9 18.9 0.14 12.0 7.0 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 ETS82049.1 - 0.18 11.6 1.3 0.96 9.2 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alb1 PF09135.6 ETS82049.1 - 0.2 12.2 9.0 0.23 12.0 5.3 1.9 2 0 0 2 2 1 0 Alb1 Macoilin PF09726.4 ETS82049.1 - 0.28 9.4 6.1 0.32 9.2 4.2 1.3 1 0 0 1 1 1 0 Transmembrane protein GvpK PF05121.7 ETS82049.1 - 0.28 11.0 9.9 0.1 12.4 2.0 2.8 1 1 1 2 2 2 0 Gas vesicle protein K TBPIP PF07106.8 ETS82049.1 - 0.77 9.2 16.4 2.5 7.6 5.3 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 ETS82049.1 - 0.81 9.6 18.0 0.75 9.7 8.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SASP PF00269.15 ETS82049.1 - 1.4 8.8 5.3 2.6 7.9 0.5 2.8 2 1 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Phage_GP20 PF06810.6 ETS82049.1 - 1.6 8.1 14.9 1.6 8.1 4.8 2.9 2 1 0 3 3 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 ETS82049.1 - 1.8 8.5 4.8 11 6.0 0.2 3.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.1 ETS82049.1 - 2.6 7.2 18.8 6.5 5.8 8.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 ETS82049.1 - 2.8 8.3 14.7 4.3 7.7 3.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 ETS82049.1 - 2.9 7.5 17.5 7.8 6.1 1.2 2.2 1 1 0 2 2 2 0 Mnd1 family Bap31 PF05529.7 ETS82049.1 - 3.5 7.0 6.7 6.5 6.1 4.1 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like SlyX PF04102.7 ETS82049.1 - 3.6 8.0 10.5 4.4 7.7 1.7 3.5 1 1 2 3 3 3 0 SlyX DUF342 PF03961.8 ETS82049.1 - 4.3 5.6 11.0 12 4.2 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2968 PF11180.3 ETS82049.1 - 5.1 6.4 13.1 0.61 9.4 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Spc24 PF08286.6 ETS82049.1 - 6.3 6.5 12.4 2.5 7.8 3.5 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.4 ETS82049.1 - 6.9 4.9 10.3 9 4.5 6.0 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 ETS82049.1 - 7.1 5.4 13.7 22 3.8 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS5 PF14817.1 ETS82049.1 - 7.5 4.9 18.0 24 3.2 11.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 TSC22 PF01166.13 ETS82049.1 - 9.5 6.2 11.4 0.26 11.3 0.5 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Lge1 PF11488.3 ETS82049.1 - 9.5 6.4 9.0 1.3e+02 2.9 6.2 2.7 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 3A PF00803.13 ETS82051.1 - 0.037 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family ACC_epsilon PF13822.1 ETS82051.1 - 0.29 11.5 2.3 0.55 10.6 1.6 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Cupin_2 PF07883.6 ETS82052.1 - 2e-06 27.1 0.1 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS82052.1 - 9.7e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 ETS82052.1 - 0.0022 17.6 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 ETS82052.1 - 0.019 14.6 0.1 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain NdhN PF11909.3 ETS82052.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N FdtA PF05523.6 ETS82052.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal ARD PF03079.9 ETS82052.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family cobW PF02492.14 ETS82053.1 - 4.8e-47 159.7 5.1 3.3e-34 117.8 0.3 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 ETS82053.1 - 2e-20 72.2 0.5 1.1e-15 57.0 0.1 2.9 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 ETS82053.1 - 0.0047 15.7 1.7 0.59 8.8 0.1 2.5 2 1 0 2 2 2 2 ArgK protein AAA_29 PF13555.1 ETS82053.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 ETS82053.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 ETS82053.1 - 0.13 12.1 0.1 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 ETS82053.1 - 0.33 10.3 2.8 14 5.0 0.5 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SNARE PF05739.14 ETS82056.1 - 9.8e-18 63.6 0.9 9.8e-18 63.6 0.7 2.8 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.20 ETS82056.1 - 5.6e-16 58.5 0.3 5.6e-16 58.5 0.2 3.3 3 1 1 4 4 4 1 Syntaxin zf-C4H2 PF10146.4 ETS82056.1 - 0.0019 18.2 1.0 0.32 10.9 0.3 2.3 1 1 1 2 2 2 2 Zinc finger-containing protein MCPsignal PF00015.16 ETS82056.1 - 0.0045 16.5 1.3 0.0045 16.5 0.9 2.5 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Atg14 PF10186.4 ETS82056.1 - 0.0061 15.5 10.3 0.023 13.6 0.1 3.0 2 1 0 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 Sed5p PF11416.3 ETS82056.1 - 0.033 13.6 0.1 0.077 12.4 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p SF-assemblin PF06705.6 ETS82056.1 - 0.077 12.1 10.5 0.33 10.0 0.7 2.6 3 0 0 3 3 3 0 SF-assemblin/beta giardin BLOC1_2 PF10046.4 ETS82056.1 - 0.24 11.5 5.8 1.1 9.4 0.5 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 ETS82056.1 - 0.28 10.9 7.9 2.9 7.7 0.1 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 ETS82056.1 - 1.1 9.1 5.2 1 9.3 0.1 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Osmo_CC PF08946.5 ETS82056.1 - 1.6 8.8 4.4 29 4.8 0.1 3.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil YkyA PF10368.4 ETS82056.1 - 1.6 8.0 5.4 6 6.1 1.8 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ApoLp-III PF07464.6 ETS82056.1 - 2.8 7.9 9.3 3.7 7.5 0.5 2.9 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF148 PF02520.12 ETS82056.1 - 4.2 7.1 10.9 1.2 8.9 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF948 PF06103.6 ETS82056.1 - 5 7.0 8.5 4.5 7.1 0.1 2.9 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 ETS82056.1 - 8.7 6.6 14.5 0.91 9.8 0.2 4.0 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.1 ETS82056.1 - 9.2 5.3 9.8 0.79 8.8 0.4 2.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Aldo_ket_red PF00248.16 ETS82057.1 - 2e-44 151.5 0.0 2.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ub-RnfH PF03658.9 ETS82057.1 - 0.14 12.0 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 RnfH family Ubiquitin SET PF00856.23 ETS82058.1 - 1.8e-12 47.8 0.6 8.7e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 SET domain ADH_N PF08240.7 ETS82059.1 - 1.9e-29 101.5 0.3 1.9e-29 101.5 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82059.1 - 1.9e-14 53.3 0.4 4.4e-14 52.1 0.3 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 ETS82059.1 - 0.00013 20.9 0.6 0.0002 20.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS82059.1 - 0.003 17.4 1.5 0.055 13.3 0.4 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS82059.1 - 0.0073 14.8 1.1 0.012 14.1 0.8 1.3 1 0 0 1 1 1 1 HI0933-like protein YdfZ PF14001.1 ETS82059.1 - 0.011 15.9 0.1 0.12 12.6 0.0 2.6 2 0 0 2 2 2 0 YdfZ protein 2-Hacid_dh_C PF02826.14 ETS82059.1 - 0.052 12.7 0.1 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 ETS82059.1 - 0.054 12.9 0.2 0.098 12.0 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.16 ETS82059.1 - 0.055 13.3 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.17 ETS82059.1 - 0.055 12.3 1.3 0.074 11.9 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS82059.1 - 0.067 13.2 1.6 0.14 12.2 0.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS82059.1 - 0.087 12.8 0.7 0.17 11.9 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS82059.1 - 0.15 11.0 4.0 0.23 10.5 2.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 ETS82059.1 - 0.19 11.8 2.1 0.81 9.7 1.5 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS82059.1 - 0.2 12.0 3.1 1.1 9.7 0.2 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS82059.1 - 1.2 7.9 4.2 2.4 6.9 2.9 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 ETS82060.1 - 1.8e-32 112.5 0.5 2.4e-32 112.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82060.1 - 4.8e-26 92.0 0.0 6.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82060.1 - 1.5e-15 57.3 1.1 4.6e-15 55.7 0.7 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82060.1 - 7.5e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS82060.1 - 0.00023 20.8 0.3 0.00042 20.0 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 ETS82060.1 - 0.004 16.0 0.2 0.021 13.7 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS82060.1 - 0.012 15.6 0.2 0.032 14.2 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 ETS82060.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 ETS82060.1 - 0.076 12.2 2.6 0.23 10.7 0.7 2.3 2 1 1 3 3 3 0 NmrA-like family DAO PF01266.19 ETS82060.1 - 0.15 10.9 0.6 1.2 7.9 0.2 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Atg14 PF10186.4 ETS82061.1 - 0.042 12.7 0.3 0.044 12.7 0.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Acetyltransf_1 PF00583.19 ETS82062.1 - 1.4e-11 44.2 0.1 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS82062.1 - 2.6e-09 37.0 0.1 3.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS82062.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipase_3 PF01764.20 ETS82063.1 - 1.5e-15 57.0 0.0 7.6e-15 54.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Glyco_hydro_43 PF04616.9 ETS82064.1 - 3.5e-27 95.2 1.2 1.1e-25 90.3 0.8 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Herpes_gE PF02480.11 ETS82066.1 - 0.00034 19.0 0.4 0.0011 17.2 0.0 1.8 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 ETS82066.1 - 0.0024 17.2 0.1 0.0039 16.6 0.1 1.4 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2453 PF10507.4 ETS82066.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) DUF4448 PF14610.1 ETS82066.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Dioxygenase_C PF00775.16 ETS82067.1 - 1.8e-11 43.6 3.2 1.1e-10 41.0 2.2 2.1 1 1 0 1 1 1 1 Dioxygenase TauD PF02668.11 ETS82069.1 - 2.7e-42 145.2 0.1 3.8e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sigma54_activ_2 PF14532.1 ETS82069.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mcp5_PH PF12814.2 ETS82070.1 - 6.5e-43 145.5 0.0 2.1e-42 143.9 0.0 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 ETS82071.1 - 4e-08 32.7 2.4 7.3e-08 31.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 ETS82071.1 - 9.3e-08 31.9 9.8 1.6e-07 31.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS82071.1 - 3.6e-07 29.7 4.8 5.8e-07 29.0 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS82071.1 - 1.1e-05 25.1 6.5 1.8e-05 24.4 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS82071.1 - 2.4e-05 23.9 7.8 4e-05 23.2 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS82071.1 - 3.6e-05 23.3 9.1 6.5e-05 22.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS82071.1 - 0.0047 16.6 3.1 0.011 15.4 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETS82071.1 - 0.053 13.3 7.8 0.12 12.2 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GMC_oxred_N PF00732.14 ETS82072.1 - 1.6e-52 178.5 0.0 2.4e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS82072.1 - 1.8e-38 132.0 0.0 3.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS82072.1 - 1.6e-06 27.2 0.0 0.018 13.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS82072.1 - 2e-06 26.9 0.1 0.00024 20.1 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS82072.1 - 3.4e-05 23.7 0.1 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS82072.1 - 9.2e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 ETS82072.1 - 0.0069 15.0 0.0 0.014 14.0 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS82072.1 - 0.0096 15.8 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS82072.1 - 0.093 12.7 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 ETS82073.1 - 7.9e-160 532.1 0.2 9.3e-160 531.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PYNP_C PF07831.8 ETS82073.1 - 0.094 12.1 0.0 0.3 10.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Cellulase PF00150.13 ETS82074.1 - 6.7e-16 58.3 0.0 7.8e-10 38.4 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 ETS82074.1 - 0.021 14.1 0.1 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 UbiA PF01040.13 ETS82075.1 - 5.1e-14 52.1 18.8 8.5e-14 51.3 13.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family SNF2_N PF00176.18 ETS82076.1 - 2.1e-66 223.7 0.6 2.9e-66 223.3 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS82076.1 - 1.3e-11 44.1 0.0 2.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS82076.1 - 3.8e-10 39.8 0.1 3.8e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS82076.1 - 9.4e-09 34.9 0.2 1.8e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 ETS82076.1 - 3.2e-06 27.0 2.6 3.2e-06 27.0 1.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.13 ETS82076.1 - 2.9e-05 23.8 36.9 0.00066 19.4 6.0 3.2 3 1 0 3 3 3 2 MYND finger zf-C3HC4 PF00097.20 ETS82076.1 - 0.00066 19.2 2.6 0.00066 19.2 1.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 ETS82076.1 - 0.0071 16.0 0.7 0.0071 16.0 0.5 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Claudin_2 PF13903.1 ETS82077.1 - 5.8e-05 22.8 1.9 5.8e-05 22.8 1.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 ETS82077.1 - 0.0004 20.0 4.9 0.0008 19.0 3.4 1.6 1 1 0 1 1 1 1 SUR7/PalI family YrhC PF14143.1 ETS82077.1 - 2.7 7.9 5.9 0.57 10.1 0.4 2.5 3 0 0 3 3 3 0 YrhC-like protein NAD_binding_8 PF13450.1 ETS82078.1 - 6e-12 45.4 0.2 1.3e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS82078.1 - 1.2e-06 27.6 1.3 1.3e-05 24.3 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS82078.1 - 6.6e-06 25.2 0.8 1.2e-05 24.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS82078.1 - 6.7e-06 26.3 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS82078.1 - 3e-05 23.9 0.1 0.00037 20.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS82078.1 - 4.8e-05 22.6 0.0 0.00025 20.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS82078.1 - 0.00016 20.2 0.3 0.00024 19.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 ETS82078.1 - 0.00017 20.8 0.0 0.0026 16.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 ETS82078.1 - 0.00051 19.2 0.5 0.0054 15.8 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 ETS82078.1 - 0.00052 19.1 0.7 0.00085 18.4 0.5 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 ETS82078.1 - 0.004 16.1 0.4 0.0074 15.2 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 ETS82078.1 - 0.014 15.7 1.4 0.025 14.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS82078.1 - 0.031 14.2 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 ETS82078.1 - 0.042 12.7 0.6 0.81 8.5 0.2 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PepSY PF03413.14 ETS82078.1 - 0.073 13.7 1.4 15 6.3 0.0 3.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain UQ_con PF00179.21 ETS82079.1 - 3.7e-48 162.5 0.0 4.1e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS82079.1 - 0.007 16.1 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Asn_synthase PF00733.16 ETS82080.1 - 5.8e-69 232.4 0.0 7.9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS82080.1 - 5.9e-37 126.1 0.0 9.5e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS82080.1 - 3e-29 101.6 0.0 5.6e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 ETS82080.1 - 1.1e-08 34.5 0.1 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 ETS82080.1 - 0.00026 19.9 0.1 0.0012 17.8 0.0 1.9 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 ETS82080.1 - 0.0014 17.4 0.1 0.038 12.7 0.0 2.5 1 1 2 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 ETS82080.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.17 ETS82081.1 - 2.2e-60 204.3 11.4 2e-59 201.1 7.9 1.9 1 1 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 ETS82082.1 - 3.1e-19 68.4 0.2 5.5e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4294 PF14127.1 ETS82083.1 - 0.013 15.0 1.3 0.046 13.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DUF3488 PF11992.3 ETS82083.1 - 0.13 10.8 4.5 0.18 10.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) SdpI PF13630.1 ETS82083.1 - 0.16 11.6 3.6 0.29 10.8 2.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2422 PF10337.4 ETS82083.1 - 3.6 6.2 8.5 0.29 9.8 2.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) Peptidase_M48 PF01435.13 ETS82086.1 - 3.5e-40 137.9 0.0 4.3e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Cyt-b5 PF00173.23 ETS82087.1 - 2.2e-18 65.8 0.2 2.4e-18 65.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 ETS82087.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H dCMP_cyt_deam_1 PF00383.17 ETS82088.1 - 2.7e-25 87.9 1.2 4.6e-25 87.2 0.8 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 ETS82088.1 - 4.6e-05 24.2 0.0 0.00013 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS82088.1 - 0.00015 22.0 0.0 0.00051 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS82088.1 - 0.0015 18.3 0.3 0.0048 16.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain ThiF PF00899.16 ETS82089.1 - 6.8e-29 100.4 0.0 1.4e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family PFK PF00365.15 ETS82089.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Shikimate_DH PF01488.15 ETS82089.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 ETS82090.1 - 3.1e-29 101.8 31.8 3.1e-29 101.8 22.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82090.1 - 2.2e-20 72.7 21.8 1.2e-19 70.2 15.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3897 PF13036.1 ETS82090.1 - 0.061 12.9 0.2 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) DnaJ PF00226.26 ETS82091.1 - 3.7e-13 48.9 0.0 6.5e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RelA_SpoT PF04607.12 ETS82092.1 - 2.3e-05 24.3 0.1 6.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Abhydrolase_3 PF07859.8 ETS82093.1 - 4.4e-27 95.0 0.0 5.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS82093.1 - 1.5e-12 46.8 0.0 1.1e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS82093.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 ETS82093.1 - 0.048 12.3 0.0 0.36 9.4 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Hydantoinase_B PF02538.9 ETS82095.1 - 2.1e-161 537.7 0.0 2.8e-161 537.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS82095.1 - 3.4e-81 272.5 0.0 6.1e-81 271.6 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS82095.1 - 1.5e-52 177.6 0.6 1.5e-50 171.1 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Abhydrolase_6 PF12697.2 ETS82096.1 - 3.7e-32 112.0 0.0 4.3e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82096.1 - 6.6e-27 94.5 0.0 1e-26 93.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82096.1 - 2.8e-18 66.0 0.1 1.4e-16 60.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS82096.1 - 8e-08 31.7 0.3 0.0058 15.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 ETS82096.1 - 5.2e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 ETS82096.1 - 0.00022 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein AXE1 PF05448.7 ETS82096.1 - 0.00038 19.0 0.6 0.073 11.5 0.0 2.4 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Ndr PF03096.9 ETS82096.1 - 0.00042 18.8 0.0 0.0006 18.3 0.0 1.4 1 1 0 1 1 1 1 Ndr family FSH1 PF03959.8 ETS82096.1 - 0.0015 18.0 0.1 0.0034 16.8 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 ETS82096.1 - 0.0036 16.9 0.0 0.026 14.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 ETS82096.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 ETS82096.1 - 0.074 13.2 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 ETS82096.1 - 0.098 11.9 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 ETS82097.1 - 2.2e-33 115.4 26.4 3.7e-33 114.6 17.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82097.1 - 4.3e-11 42.0 23.8 7.9e-10 37.8 13.6 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS82097.1 - 0.0032 17.2 0.1 0.01 15.5 0.1 1.9 1 0 0 1 1 1 1 MFS_1 like family Cu-oxidase_3 PF07732.10 ETS82098.1 - 3.9e-41 139.4 4.0 1.7e-38 130.9 0.7 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS82098.1 - 6.1e-40 135.9 2.4 1.9e-34 118.0 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS82098.1 - 3.3e-29 101.8 0.3 2e-21 76.5 0.2 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 ETS82098.1 - 0.03 14.2 0.0 13 5.7 0.0 3.0 3 0 0 3 3 3 0 Cupredoxin-like domain COX2 PF00116.15 ETS82098.1 - 0.11 12.2 0.0 18 5.2 0.0 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, periplasmic domain RHIM PF12721.2 ETS82098.1 - 5.9 7.3 8.5 6.6 7.2 0.6 4.0 4 0 0 4 4 4 0 RIP homotypic interaction motif ketoacyl-synt PF00109.21 ETS82099.1 - 7.3e-71 238.6 0.0 1.4e-70 237.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS82099.1 - 3.1e-52 177.8 0.0 1.4e-51 175.6 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 ETS82099.1 - 1.7e-40 139.6 0.1 8e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 ETS82099.1 - 2.8e-34 117.5 0.5 1.1e-33 115.6 0.3 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 ETS82099.1 - 2.9e-21 75.5 3.4 5.2e-11 42.6 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 ETS82099.1 - 4.8e-13 48.9 0.0 1.6e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 ETS82099.1 - 2.7e-05 24.1 6.2 9.7e-05 22.3 0.0 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 ETS82099.1 - 0.00058 18.9 0.1 0.0014 17.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain NYD-SP12_N PF15015.1 ETS82099.1 - 0.21 9.7 0.0 0.34 9.0 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Zn_clus PF00172.13 ETS82100.1 - 5.7e-08 32.5 5.6 5.7e-08 32.5 3.9 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 ETS82101.1 - 3.7e-30 105.0 0.5 4.9e-30 104.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82101.1 - 2.8e-29 102.6 0.0 4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82101.1 - 2.6e-13 50.0 0.2 3.9e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 ETS82102.1 - 3.5e-05 23.6 9.1 3.5e-05 23.6 6.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 ETS82103.1 - 3.5e-14 53.0 0.0 7.3e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS82103.1 - 4e-06 26.6 0.0 8.6e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 ETS82103.1 - 0.0066 15.3 0.0 0.0081 15.1 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS82103.1 - 0.036 13.4 0.0 0.16 11.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS82103.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HET PF06985.6 ETS82105.1 - 1.3e-24 86.9 0.0 2.7e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAMSAP_CH PF11971.3 ETS82105.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Sugar_tr PF00083.19 ETS82106.1 - 2.9e-89 299.7 24.0 3.7e-89 299.3 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82106.1 - 7e-17 61.1 38.2 2e-13 49.8 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1443 PF07280.6 ETS82106.1 - 0.015 14.8 0.1 0.047 13.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) Kelch_3 PF13415.1 ETS82107.1 - 1.1e-29 101.8 13.0 6.8e-08 32.4 0.0 8.5 9 1 0 9 9 9 6 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS82107.1 - 3.4e-25 87.5 10.3 1.3e-07 31.2 0.0 6.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS82107.1 - 7.1e-20 70.5 0.3 4.5e-05 23.3 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 ETS82107.1 - 5.3e-19 67.5 0.3 1.4e-05 25.0 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 ETS82107.1 - 3.2e-16 58.5 1.9 8.5e-06 25.2 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 ETS82107.1 - 7.8e-13 47.6 1.7 2.2e-05 24.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.9 ETS82107.1 - 0.26 9.9 0.1 1.7 7.3 0.0 2.3 3 0 0 3 3 3 0 Recombination activating protein 2 2Fe-2S_thioredx PF01257.14 ETS82108.1 - 9.6e-59 197.1 0.1 1.2e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SBP_bac_7 PF03480.8 ETS82108.1 - 0.089 11.8 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 AhpC-TSA PF00578.16 ETS82109.1 - 6.3e-23 80.8 0.0 1.1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS82109.1 - 4.7e-13 48.9 0.0 7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 ETS82109.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme BAR PF03114.13 ETS82110.1 - 6.2e-67 225.4 3.7 7.8e-67 225.1 2.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 ETS82110.1 - 7.1e-16 57.3 0.1 1.2e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS82110.1 - 6e-14 51.3 0.1 1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS82110.1 - 1.7e-10 40.2 0.0 4.5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain MCPVI PF02993.9 ETS82110.1 - 0.0053 16.9 0.6 0.0053 16.9 0.4 2.1 2 1 0 2 2 2 1 Minor capsid protein VI Vps5 PF09325.5 ETS82110.1 - 0.01 15.0 5.8 1.2 8.3 2.3 2.3 2 0 0 2 2 2 0 Vps5 C terminal like AHS1 PF02682.11 ETS82110.1 - 0.03 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Aminotran_5 PF00266.14 ETS82111.1 - 7.4e-94 314.5 0.0 9.4e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 ETS82111.1 - 1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 ETS82111.1 - 2.9e-06 26.5 0.0 1.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 ETS82111.1 - 0.022 13.2 0.0 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 ETS82111.1 - 0.049 11.9 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme cNMP_binding PF00027.24 ETS82112.1 - 8e-41 137.7 0.0 1.9e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 ETS82112.1 - 7.6e-07 28.4 0.2 1.5e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit BCAS2 PF05700.6 ETS82113.1 - 3.5e-50 170.5 1.7 4.2e-50 170.2 1.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 ETS82113.1 - 0.13 12.0 3.5 0.062 13.0 0.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.1 ETS82113.1 - 0.3 10.0 5.6 0.29 10.0 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ceramidase_alk PF04734.8 ETS82114.1 - 9.2e-278 922.6 0.0 1e-277 922.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase dCMP_cyt_deam_1 PF00383.17 ETS82115.1 - 6e-11 41.9 0.0 8.3e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETS82115.1 - 0.13 11.9 0.2 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Cu-oxidase PF00394.17 ETS82116.1 - 5.1e-40 136.9 0.7 1.6e-39 135.3 0.1 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS82116.1 - 3e-38 130.4 11.0 9.9e-38 128.7 0.6 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS82116.1 - 4.9e-36 123.0 8.1 3.6e-35 120.2 2.7 3.7 3 1 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 ETS82117.1 - 8.2e-33 113.5 26.7 1.1e-32 113.1 18.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.1 ETS82118.1 - 3.5e-57 193.8 49.5 4.4e-57 193.5 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS82118.1 - 2.8e-26 91.9 42.7 3.7e-26 91.5 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease APG5 PF04106.7 ETS82119.1 - 6e-42 143.3 0.0 1.5e-41 142.0 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.13 ETS82120.1 - 3.4e-09 36.4 13.3 5.6e-09 35.7 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AKNA PF12443.3 ETS82120.1 - 0.058 13.4 6.6 0.075 13.0 0.1 3.2 1 1 2 3 3 3 0 AT-hook-containing transcription factor WD40 PF00400.27 ETS82123.1 - 6.6e-35 117.7 14.8 3.1e-11 42.7 0.4 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 ETS82123.1 - 5.9e-05 21.4 1.4 1.2 7.1 0.0 3.4 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Snf7 PF03357.16 ETS82126.1 - 3.2e-32 111.2 21.8 3.2e-32 111.2 15.1 2.0 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.6 ETS82126.1 - 0.055 12.7 7.4 0.081 12.2 5.1 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein MutS_III PF05192.13 ETS82126.1 - 0.59 9.8 3.9 0.73 9.5 2.7 1.2 1 0 0 1 1 1 0 MutS domain III Prefoldin_2 PF01920.15 ETS82126.1 - 1.5 8.5 20.6 0.41 10.4 6.0 3.3 1 1 1 3 3 3 0 Prefoldin subunit HK97-gp10_like PF04883.7 ETS82126.1 - 1.8 9.5 4.5 3.8 8.5 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component DUF3138 PF11336.3 ETS82126.1 - 7.8 4.5 11.0 2.2 6.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) MFS_1 PF07690.11 ETS82127.1 - 3.2e-52 177.4 49.8 1.7e-42 145.4 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS82127.1 - 8.3e-05 21.1 34.2 0.00039 18.9 9.4 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1500 PF07389.7 ETS82127.1 - 0.051 13.5 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) RRP7 PF12923.2 ETS82128.1 - 1.8e-32 112.0 12.8 1.8e-32 112.0 8.9 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Usp PF00582.21 ETS82128.1 - 9.8 6.3 9.1 1.5 8.9 0.4 2.4 2 1 1 3 3 3 0 Universal stress protein family DUF3115 PF11312.3 ETS82129.1 - 1.4e-78 263.9 0.1 1.7e-62 211.0 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3115) FGF-BP1 PF06473.7 ETS82129.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.8 3 0 0 3 3 3 0 FGF binding protein 1 (FGF-BP1) dsrm PF00035.20 ETS82129.1 - 1.7 9.3 7.1 3 8.5 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Syja_N PF02383.13 ETS82130.1 - 2.4e-96 322.2 0.0 3.3e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 ETS82130.1 - 9.2e-37 124.9 0.0 1.6e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Ribosomal_L7Ae PF01248.21 ETS82131.1 - 4.2e-24 83.8 0.0 4.9e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 ETS82131.1 - 5.8e-05 22.9 0.1 7.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 ETS82131.1 - 0.0075 16.0 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.16 ETS82132.1 - 1.2e-30 105.1 32.3 1.1e-18 66.8 8.6 2.4 3 0 0 3 3 3 2 ATP synthase subunit C ABA_GPCR PF12430.3 ETS82132.1 - 0.15 11.1 0.6 2.5 7.1 0.1 2.0 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 ETS82132.1 - 0.26 10.8 4.2 0.085 12.4 0.8 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Pkinase PF00069.20 ETS82133.1 - 3.6e-06 26.3 0.0 1.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82133.1 - 0.0036 16.3 0.0 0.0053 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETS82134.1 - 0.0093 15.1 0.0 0.017 14.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain TPR_12 PF13424.1 ETS82137.1 - 1.1e-05 25.2 1.3 0.00053 19.8 0.4 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS82137.1 - 0.03 14.2 4.7 1.7 8.6 0.1 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat RasGEF_N_2 PF14663.1 ETS82137.1 - 0.048 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HATPase_c PF02518.21 ETS82138.1 - 7.3e-29 99.7 0.0 1.9e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS82138.1 - 2.1e-27 95.3 0.5 3.5e-27 94.6 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 ETS82138.1 - 3.2e-13 49.4 0.0 8.3e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 ETS82138.1 - 0.0002 21.4 0.9 1.1 9.5 0.0 3.8 3 1 0 3 3 3 2 HAMP domain SPT16 PF08644.6 ETS82139.1 - 7e-56 188.2 0.1 7e-56 188.2 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 ETS82139.1 - 3.5e-52 176.2 0.1 3.5e-52 176.2 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 ETS82139.1 - 4.6e-22 77.8 0.0 1.2e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 ETS82139.1 - 3.3e-21 75.8 0.0 5.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Chromo PF00385.19 ETS82140.1 - 6.3e-15 54.5 0.7 1.3e-14 53.5 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Hid1 PF12722.2 ETS82140.1 - 5.8 4.4 12.6 1.6 6.2 6.8 1.4 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein SUR7 PF06687.7 ETS82142.1 - 9.4e-26 90.6 11.6 9.4e-26 90.6 8.0 1.4 1 1 0 1 1 1 1 SUR7/PalI family Abhydrolase_9_N PF15420.1 ETS82142.1 - 0.022 14.5 0.7 0.047 13.4 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus ASFV_J13L PF05568.6 ETS82142.1 - 0.33 10.4 0.0 0.33 10.4 0.0 2.1 1 1 1 2 2 2 0 African swine fever virus J13L protein Orbi_NS3 PF01616.11 ETS82142.1 - 0.7 8.8 3.7 0.46 9.4 1.2 1.6 2 0 0 2 2 2 0 Orbivirus NS3 zf-LITAF-like PF10601.4 ETS82142.1 - 4.2 7.3 12.2 0.12 12.2 0.4 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF4293 PF14126.1 ETS82142.1 - 4.8 7.0 7.6 1.7 8.5 2.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Ric8 PF10165.4 ETS82143.1 - 7.1e-116 387.6 0.0 8.4e-116 387.4 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn NUC130_3NT PF08158.7 ETS82143.1 - 0.044 14.0 0.0 8.5 6.7 0.0 2.9 2 0 0 2 2 2 0 NUC130/3NT domain Rif1_N PF12231.3 ETS82144.1 - 1.6e-135 451.9 8.6 2.2e-135 451.3 6.0 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.15 ETS82145.1 - 1.2e-41 142.8 0.0 1.5e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 ETS82145.1 - 0.045 12.3 0.0 0.081 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DAHP_synth_2 PF01474.11 ETS82146.1 - 2.7e-195 648.8 0.0 3e-195 648.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TPR_MLP1_2 PF07926.7 ETS82147.1 - 0.85 9.3 6.2 1.1 9.0 4.3 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein VPS28 PF03997.7 ETS82149.1 - 1e-54 184.9 0.1 1.2e-54 184.7 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 ETS82149.1 - 0.022 14.5 3.5 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 ETS82150.1 - 3.9e-121 403.5 0.0 7.8e-121 402.5 0.0 1.5 1 0 0 1 1 1 1 Noc2p family TraC_F_IV PF11130.3 ETS82151.1 - 0.043 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer adh_short PF00106.20 ETS82152.1 - 1.4e-27 96.6 0.0 1.8e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82152.1 - 5.9e-13 48.8 0.0 9.7e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS82152.1 - 2.2e-10 40.7 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 ETS82152.1 - 4.2e-05 23.2 0.5 0.00017 21.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF771 PF05595.6 ETS82152.1 - 0.093 12.6 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF771) Pro-kuma_activ PF09286.6 ETS82154.1 - 0.0037 17.3 0.8 0.015 15.3 0.5 1.9 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Aldo_ket_red PF00248.16 ETS82155.1 - 4.1e-50 170.1 0.0 4.8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 ETS82156.1 - 4.8e-41 137.7 22.9 5.4e-13 48.2 1.7 6.9 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS82156.1 - 5.1e-22 77.3 20.7 5.9e-08 32.3 2.1 5.2 4 1 2 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 ETS82156.1 - 8.1e-13 47.0 17.7 0.031 14.3 0.3 9.7 7 4 3 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 ETS82156.1 - 6.8e-11 40.6 21.5 0.16 12.0 0.1 9.7 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.1 ETS82156.1 - 1e-09 38.2 8.5 8e-05 22.2 3.9 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 ETS82156.1 - 7.1e-09 34.4 13.0 0.59 10.5 0.0 8.2 9 0 0 9 9 9 3 Leucine rich repeat IF4E PF01652.13 ETS82156.1 - 0.052 13.0 0.0 0.59 9.6 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic initiation factor 4E Abhydrolase_5 PF12695.2 ETS82158.1 - 1.1e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82158.1 - 6.9e-05 22.8 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS82158.1 - 0.00041 19.9 0.0 0.00069 19.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS82158.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_8 PF08022.7 ETS82160.1 - 9.2e-23 80.1 0.0 2.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS82160.1 - 1.4e-22 80.2 0.0 2.2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 ETS82160.1 - 1e-16 61.1 10.1 1e-16 61.1 7.0 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 ETS82160.1 - 0.00024 21.1 0.0 0.00071 19.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Myosin_head PF00063.16 ETS82161.1 - 4.3e-232 772.0 5.2 6.7e-232 771.3 3.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 ETS82161.1 - 1.3e-40 138.8 0.0 4.7e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 ETS82161.1 - 2.5e-12 45.9 0.2 4.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS82161.1 - 4.8e-10 38.8 0.1 1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS82161.1 - 2.9e-08 33.0 0.1 7.5e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 ETS82161.1 - 0.0033 17.5 0.1 0.011 15.9 0.1 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain IQ PF00612.22 ETS82161.1 - 0.0035 16.8 8.1 0.039 13.6 1.6 2.7 1 1 1 2 2 2 1 IQ calmodulin-binding motif GCFC PF07842.7 ETS82161.1 - 0.0036 16.7 0.0 0.009 15.4 0.0 1.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein AAA_22 PF13401.1 ETS82161.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS82161.1 - 0.013 14.6 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETS82161.1 - 0.019 15.7 0.0 0.054 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 ETS82161.1 - 0.033 13.5 0.2 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 ETS82161.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 ETS82161.1 - 0.081 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF552 PF04472.7 ETS82161.1 - 0.13 12.1 0.0 0.59 10.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF552) zf-DHHC PF01529.15 ETS82162.1 - 3e-34 117.9 0.0 5.8e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase RRM_1 PF00076.17 ETS82163.1 - 3e-14 52.3 0.0 4.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS82163.1 - 3.9e-11 42.7 0.0 6.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS82163.1 - 3.6e-08 33.1 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 ETS82164.1 - 8.8e-23 80.5 33.3 3.8e-14 52.1 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82164.1 - 8.3e-15 54.2 21.2 2.3e-14 52.8 14.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Pex14_N PF04695.8 ETS82164.1 - 0.0093 16.0 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Lipase_GDSL_2 PF13472.1 ETS82165.1 - 9.1e-15 55.2 2.6 9.1e-15 55.2 1.8 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 ETS82165.1 - 9e-13 47.6 8.2 1.9e-12 46.6 5.7 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 ETS82165.1 - 6.6e-07 29.3 0.2 1.2e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 ETS82165.1 - 0.00022 21.5 4.2 0.0034 17.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4397) Lipase_GDSL_3 PF14606.1 ETS82165.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FliD_N PF02465.13 ETS82165.1 - 5.6 7.3 12.9 8.3 6.8 3.6 3.2 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MFS_1 PF07690.11 ETS82166.1 - 1.3e-11 43.8 50.7 1.3e-11 43.8 35.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily APG6 PF04111.7 ETS82167.1 - 3.5e-119 397.5 0.0 4.3e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 ETS82167.1 - 0.082 10.7 6.0 0.11 10.3 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 ETS82167.1 - 0.28 11.5 5.7 0.045 14.1 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PA26 PF04636.8 ETS82167.1 - 0.47 9.0 3.3 0.71 8.5 2.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 ETS82167.1 - 3 7.3 11.6 5.2 6.6 8.1 1.3 1 0 0 1 1 1 0 IncA protein Scm3 PF10384.4 ETS82168.1 - 1.7e-23 81.8 1.2 3.5e-23 80.8 0.4 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 Pkinase PF00069.20 ETS82169.1 - 1.2e-59 201.6 0.1 1.3e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82169.1 - 9.1e-20 70.8 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS82169.1 - 2.2e-07 30.8 0.0 8e-06 25.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS82169.1 - 0.0091 15.5 0.1 0.028 13.9 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 ETS82169.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 ETS82169.1 - 0.039 13.0 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS82169.1 - 0.092 12.0 0.4 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Aconitase_B_N PF11791.3 ETS82169.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain DUF3807 PF12720.2 ETS82170.1 - 5.5e-42 143.8 7.5 7.4e-42 143.4 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 ETS82170.1 - 0.016 15.2 1.0 0.021 14.8 0.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family N_NLPC_P60 PF12912.2 ETS82171.1 - 0.095 12.7 1.0 0.17 11.9 0.7 1.6 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Peptidase_C10 PF01640.12 ETS82171.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C10 family Atg14 PF10186.4 ETS82172.1 - 1.1e-76 257.6 0.0 1.4e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AIP3 PF03915.8 ETS82172.1 - 0.0004 19.4 1.1 0.00058 18.8 0.8 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4200 PF13863.1 ETS82172.1 - 0.53 10.2 8.1 0.39 10.6 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Cluap1 PF10234.4 ETS82172.1 - 0.81 8.8 8.2 1.4 8.0 5.2 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_M24 PF00557.19 ETS82174.1 - 2.3e-08 33.8 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Terpene_synth_C PF03936.11 ETS82176.1 - 1.8e-06 27.4 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PilJ PF13675.1 ETS82176.1 - 0.084 13.1 0.2 0.34 11.2 0.1 2.0 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term LCCL PF03815.14 ETS82178.1 - 1.6e-15 56.8 0.0 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 LCCL domain EpsG PF14897.1 ETS82178.1 - 0.08 11.8 9.3 0.066 12.1 5.4 1.5 2 0 0 2 2 2 0 EpsG family eIF-5_eIF-2B PF01873.12 ETS82180.1 - 1.1e-45 154.2 0.3 1.6e-45 153.7 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PKI PF02827.11 ETS82180.1 - 0.029 14.4 3.1 0.029 14.4 2.1 2.9 2 1 1 3 3 3 0 cAMP-dependent protein kinase inhibitor Lar_restr_allev PF14354.1 ETS82180.1 - 0.085 13.1 0.3 0.29 11.4 0.2 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 ETS82180.1 - 1.9 8.7 6.7 1.8 8.7 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.7 ETS82180.1 - 3.3 7.2 5.4 2.9 7.3 2.2 2.0 2 1 0 2 2 2 0 HypF finger DAO PF01266.19 ETS82181.1 - 4.6e-53 180.3 0.1 7.5e-53 179.6 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS82181.1 - 0.0016 17.4 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS82181.1 - 0.0057 16.6 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS82181.1 - 0.043 12.6 0.0 0.088 11.6 0.0 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 ETS82181.1 - 0.086 11.9 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 ETS82181.1 - 0.15 11.8 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 ETS82181.1 - 0.17 10.0 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) INO80_Ies4 PF08193.6 ETS82182.1 - 4.8e-71 239.2 25.1 6.1e-71 238.9 17.4 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 ETS82183.1 - 5.2e-34 117.0 1.2 5.2e-34 117.0 0.8 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 ETS82183.1 - 2.5e-21 76.0 0.2 5.6e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 ETS82183.1 - 2.8e-06 26.9 2.8 8.7e-06 25.3 0.0 2.7 3 0 0 3 3 3 1 LisH GST_C_2 PF13410.1 ETS82185.1 - 3.5e-05 23.6 0.7 7.6e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS82185.1 - 7.7e-05 23.1 0.1 0.00011 22.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 ETS82185.1 - 0.00012 22.2 0.0 0.00083 19.5 0.0 2.2 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein DUF2731 PF10806.3 ETS82185.1 - 0.029 14.6 0.2 0.21 11.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2731) adh_short PF00106.20 ETS82186.1 - 3.3e-26 92.1 0.7 4.7e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82186.1 - 9.7e-25 87.7 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82186.1 - 1.9e-08 34.1 0.1 3.9e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS82186.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavin_Reduct PF01613.13 ETS82187.1 - 1.1e-25 90.2 0.2 1.5e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain TPMT PF05724.6 ETS82188.1 - 1e-28 100.2 0.0 1.4e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 ETS82188.1 - 9.8e-09 35.2 0.3 2.4e-08 34.0 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82188.1 - 3.2e-08 34.1 0.0 5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS82188.1 - 6.6e-08 32.4 0.0 9.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS82188.1 - 6.2e-07 29.8 0.0 9.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS82188.1 - 2.7e-06 27.7 0.0 5.2e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82188.1 - 3.3e-06 26.7 0.0 0.0009 18.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 ETS82188.1 - 0.0017 18.6 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 ETS82188.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 ETS82188.1 - 0.15 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein DUF3433 PF11915.3 ETS82189.1 - 1.4e-35 121.3 17.5 8.2e-22 77.1 1.6 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Ras PF00071.17 ETS82190.1 - 3.9e-52 175.8 0.0 6.9e-52 175.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 ETS82190.1 - 3.2e-18 66.3 0.1 2.6e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS82190.1 - 0.00023 20.4 0.0 0.00076 18.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS82190.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS82190.1 - 0.027 13.7 0.1 0.28 10.4 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 ETS82190.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 ETS82190.1 - 0.08 12.3 0.2 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS82191.1 - 2.1e-50 170.5 0.2 5.6e-27 94.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS82191.1 - 2.5e-29 102.5 36.7 8.2e-29 100.8 9.7 2.9 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 ETS82191.1 - 4.6e-11 43.0 0.6 9.5e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 ETS82191.1 - 3.4e-10 39.5 2.5 7e-05 22.1 0.4 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS82191.1 - 1e-08 34.5 0.3 0.002 17.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 ETS82191.1 - 1.3e-08 35.1 0.2 0.027 14.4 0.2 4.3 3 1 0 4 4 4 1 AAA domain Miro PF08477.8 ETS82191.1 - 1.3e-06 28.8 0.1 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 ETS82191.1 - 1.8e-06 27.2 0.2 0.037 13.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS82191.1 - 3.7e-06 26.5 0.0 0.018 14.5 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 ETS82191.1 - 3.9e-06 27.0 0.4 0.1 12.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 ETS82191.1 - 5e-06 26.4 0.0 0.079 12.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 ETS82191.1 - 7e-05 23.6 0.1 0.17 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS82191.1 - 7.9e-05 22.1 2.9 0.15 11.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS82191.1 - 0.00014 22.2 0.3 0.081 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS82191.1 - 0.00018 21.4 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS82191.1 - 0.00048 19.1 0.1 0.013 14.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 ETS82191.1 - 0.00053 20.1 0.1 0.77 9.9 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 ETS82191.1 - 0.00067 19.2 0.0 0.057 12.9 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF815 PF05673.8 ETS82191.1 - 0.0009 18.2 0.0 0.51 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MobB PF03205.9 ETS82191.1 - 0.0017 18.1 0.2 2.3 7.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 ETS82191.1 - 0.0019 17.6 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS82191.1 - 0.0022 17.8 0.3 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 ETS82191.1 - 0.0031 17.3 3.2 0.45 10.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 ETS82191.1 - 0.0039 17.3 0.1 12 6.1 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 ETS82191.1 - 0.0048 17.1 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS82191.1 - 0.0068 15.8 0.3 4 6.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 ETS82191.1 - 0.012 14.7 0.1 3 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 ETS82191.1 - 0.012 15.2 0.7 2.3 7.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.17 ETS82191.1 - 0.014 14.2 0.3 2.7 6.7 0.1 2.7 2 1 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 ETS82191.1 - 0.021 14.7 0.9 1.6 8.7 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 ETS82191.1 - 0.022 14.2 0.1 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 ETS82191.1 - 0.025 13.2 0.4 0.31 9.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 ETS82191.1 - 0.095 12.3 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 ETS82191.1 - 0.098 12.3 2.7 10 5.8 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF3987 PF13148.1 ETS82191.1 - 0.11 10.9 0.1 1.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Septin PF00735.13 ETS82191.1 - 0.13 11.2 0.0 14 4.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 ETS82191.1 - 0.45 9.4 0.0 1.3 8.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain YrhK PF14145.1 ETS82192.1 - 3.5e-05 23.3 21.8 0.11 12.1 0.2 4.8 3 2 1 4 4 4 3 YrhK-like protein Mcp5_PH PF12814.2 ETS82193.1 - 1.5e-46 157.3 0.0 3.8e-46 156.0 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 ETS82193.1 - 1.6 8.4 19.2 5.6 6.7 12.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein OTU PF02338.14 ETS82194.1 - 4.6e-21 75.6 0.0 2.7e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 ETS82194.1 - 3.4e-05 23.3 0.0 0.011 15.0 0.0 2.6 3 0 0 3 3 3 2 Peptidase C65 Otubain Daxx PF03344.10 ETS82194.1 - 0.35 9.2 17.5 0.4 9.1 12.2 1.1 1 0 0 1 1 1 0 Daxx Family Aldedh PF00171.17 ETS82195.1 - 1.4e-13 49.9 5.3 5.4e-10 38.2 2.3 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 ETS82195.1 - 0.0061 15.5 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PALP PF00291.20 ETS82196.1 - 2.5e-62 210.8 0.2 3.7e-62 210.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.7 ETS82197.1 - 1.9e-45 154.1 0.0 3e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 ETS82197.1 - 1.5e-44 151.4 0.0 2.3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 ETS82197.1 - 0.12 12.8 2.0 0.2 12.1 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.21 ETS82198.1 - 6.3e-35 119.6 0.0 9.2e-35 119.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 ETS82198.1 - 0.0066 16.1 0.1 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 ETS82198.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Chitin_synth_1 PF01644.12 ETS82199.1 - 6.1e-71 237.4 0.0 1e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 ETS82199.1 - 5.7e-27 93.2 0.0 9.9e-27 92.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 ETS82199.1 - 2.3e-26 92.2 0.3 1.6e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS82199.1 - 1.8e-09 37.5 8.3 3.1e-08 33.5 5.7 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS82199.1 - 4.2e-07 30.0 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Opy2 PF09463.5 ETS82200.1 - 1.6e-08 34.4 21.3 2.7e-08 33.7 14.8 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 ETS82200.1 - 0.051 13.2 0.2 0.098 12.3 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2797 PF10977.3 ETS82200.1 - 0.23 11.0 5.1 0.38 10.3 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Con-6 PF10346.4 ETS82201.1 - 2.7e-28 97.0 8.0 9.4e-17 60.1 0.9 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 ETS82201.1 - 0.012 15.1 2.0 0.045 13.2 0.2 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein UPF0546 PF10639.4 ETS82202.1 - 6.3e-38 129.0 0.1 8e-38 128.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 ETS82202.1 - 0.00014 21.8 2.6 0.0052 16.8 2.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 ETS82202.1 - 0.0097 16.0 2.1 0.0097 16.0 1.5 1.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF485 PF04341.7 ETS82202.1 - 0.0098 15.5 0.8 0.23 11.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF485 DUF3429 PF11911.3 ETS82202.1 - 0.31 11.0 3.3 0.86 9.5 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) CH PF00307.26 ETS82204.1 - 4.4e-61 203.6 0.0 8.7e-16 57.9 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 ETS82204.1 - 1.5e-05 24.9 0.3 0.00024 21.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 ETS82204.1 - 0.00024 20.6 0.0 32 4.2 0.0 4.4 4 0 0 4 4 4 0 CAMSAP CH domain EF-hand_1 PF00036.27 ETS82204.1 - 0.0037 16.4 0.4 0.99 8.8 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 ETS82204.1 - 0.042 13.7 1.1 0.74 9.8 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain MBOAT PF03062.14 ETS82205.1 - 4.4e-35 121.3 19.6 4.4e-35 121.3 13.6 2.4 2 2 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 ETS82205.1 - 2.8e-06 27.3 5.6 6.4e-06 26.1 3.9 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Epimerase PF01370.16 ETS82206.1 - 1.8e-21 76.6 0.0 2.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS82206.1 - 1.5e-09 37.0 0.0 1.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS82206.1 - 4.6e-09 36.5 0.1 8.4e-09 35.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS82206.1 - 1.7e-08 33.7 0.0 4.3e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 ETS82206.1 - 4.2e-07 30.0 0.1 7.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS82206.1 - 0.00019 20.4 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS82206.1 - 0.00028 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 ETS82206.1 - 0.0053 16.0 0.1 0.062 12.5 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 ETS82206.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.1 ETS82206.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Kelch_1 PF01344.20 ETS82206.1 - 0.23 11.0 0.9 4.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Kelch motif FAD_binding_3 PF01494.14 ETS82207.1 - 3.4e-20 72.4 2.3 1.6e-19 70.1 1.6 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS82207.1 - 8.1e-08 31.5 3.5 8.5e-05 21.6 1.7 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 ETS82207.1 - 0.00089 18.1 0.0 0.074 11.8 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 ETS82207.1 - 0.008 16.1 0.4 0.025 14.5 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS82207.1 - 0.021 15.2 1.8 0.021 15.2 1.3 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-GRF PF06839.7 ETS82207.1 - 0.05 13.5 0.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 GRF zinc finger Pyr_redox_2 PF07992.9 ETS82207.1 - 0.087 12.6 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dabb PF07876.7 ETS82207.1 - 0.11 12.9 0.1 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain RCR PF12273.3 ETS82208.1 - 0.0045 17.5 0.8 0.0049 17.4 0.6 1.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red UTP15_C PF09384.5 ETS82210.1 - 9.1e-46 155.2 0.0 1.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 ETS82210.1 - 3.1e-23 80.7 4.6 3.3e-08 33.1 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ECH PF00378.15 ETS82211.1 - 2.5e-41 141.4 0.1 3.8e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 ETS82211.1 - 0.0046 17.0 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DUF1180 PF06679.7 ETS82212.1 - 0.025 14.4 0.5 0.067 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Rifin_STEVOR PF02009.11 ETS82212.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family MFS_2 PF13347.1 ETS82212.1 - 0.059 11.7 0.0 0.071 11.4 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4381 PF14316.1 ETS82212.1 - 0.06 13.4 0.1 0.092 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Chordopox_A13L PF05961.6 ETS82212.1 - 0.12 12.2 0.1 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TMEM154 PF15102.1 ETS82212.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.3 ETS82212.1 - 1 9.9 10.7 3.5 8.1 7.4 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Cellulase PF00150.13 ETS82213.1 - 4.4e-17 62.1 0.8 6.4e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 ETS82213.1 - 2.1e-13 49.6 6.5 2.1e-13 49.6 4.5 2.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Cellulase-like PF12876.2 ETS82213.1 - 0.00012 22.4 0.0 0.0003 21.1 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 ETS82213.1 - 0.00079 18.4 0.0 0.0012 17.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 ETS82213.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase Glyoxalase_2 PF12681.2 ETS82213.1 - 0.066 13.8 0.0 0.82 10.2 0.0 2.6 1 1 0 2 2 2 0 Glyoxalase-like domain MSP1_C PF07462.6 ETS82213.1 - 0.22 9.8 7.9 0.32 9.3 5.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCHC PF00098.18 ETS82214.1 - 1.6e-54 179.3 100.7 4.6e-07 29.4 3.2 10.5 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_2 PF13696.1 ETS82214.1 - 1e-09 37.7 48.2 0.0044 16.4 0.2 9.2 5 3 4 9 9 9 6 Zinc knuckle zf-CCHC_3 PF13917.1 ETS82214.1 - 1.5e-08 34.2 71.2 0.0042 16.7 0.5 10.1 2 2 8 10 10 10 9 Zinc knuckle zf-CCHC_4 PF14392.1 ETS82214.1 - 2.5e-08 33.4 69.5 0.31 10.7 0.4 10.4 8 2 2 10 10 10 9 Zinc knuckle zf-CCHC_6 PF15288.1 ETS82214.1 - 0.016 14.8 82.8 0.022 14.4 1.5 10.3 8 2 2 10 10 10 0 Zinc knuckle MFS_1 PF07690.11 ETS82216.1 - 1.1e-39 136.1 52.6 2.8e-39 134.8 32.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS82216.1 - 6e-11 41.2 12.7 6e-11 41.2 8.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CMD PF02627.15 ETS82217.1 - 5e-10 39.0 1.4 3.2e-09 36.5 0.6 2.2 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.13 ETS82217.1 - 0.029 13.6 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 BRCA2 repeat DUF4131 PF13567.1 ETS82218.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 ETS82219.1 - 2.3e-07 30.2 0.0 6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 ETS82219.1 - 7.5e-07 29.1 5.4 0.00057 19.6 2.2 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 ETS82219.1 - 3.3e-05 23.0 0.0 6.8e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS82219.1 - 3.5e-05 22.9 0.0 0.092 11.8 0.0 2.9 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 ETS82219.1 - 0.00074 18.9 0.2 0.13 11.6 0.0 2.4 2 1 0 2 2 2 1 RIO1 family Aldo_ket_red PF00248.16 ETS82220.1 - 6.6e-13 48.1 0.0 8.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Maf1 PF09174.5 ETS82221.1 - 1.3e-56 191.2 0.0 2.8e-56 190.2 0.0 1.6 2 0 0 2 2 2 1 Maf1 regulator Clat_adaptor_s PF01217.15 ETS82221.1 - 5.9e-50 168.6 0.9 8.7e-50 168.1 0.6 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIIA PF03153.8 ETS82221.1 - 0.006 16.5 0.3 0.0072 16.2 0.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3129 PF11327.3 ETS82223.1 - 2.6e-71 239.2 9.4 4.4e-71 238.5 6.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) AMP-binding PF00501.23 ETS82224.1 - 1.3e-79 267.5 0.0 1.7e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS82224.1 - 1e-11 45.5 0.3 2.2e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WAP PF00095.16 ETS82225.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' SNF2_N PF00176.18 ETS82226.1 - 3.9e-09 35.7 0.0 6.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 ETS82227.1 - 1.4e-19 69.9 0.0 2.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS82227.1 - 7e-10 38.6 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 ETS82227.1 - 0.0049 16.5 9.6 0.01 15.5 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS82227.1 - 0.0059 16.2 8.9 0.014 15.0 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS82227.1 - 0.0076 16.2 10.3 0.017 15.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS82227.1 - 0.21 11.4 9.6 0.49 10.2 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 ETS82227.1 - 0.81 9.4 6.8 0.58 9.9 3.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 ETS82227.1 - 0.91 9.4 9.4 2.2 8.2 6.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS82227.1 - 9.1 6.0 11.5 21 4.9 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UcrQ PF02939.11 ETS82229.1 - 8.2e-32 108.8 0.5 9.7e-32 108.6 0.3 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 ETS82230.1 - 8.5e-24 84.4 3.9 1.4e-23 83.7 2.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 ETS82230.1 - 0.014 14.7 1.3 0.021 14.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) GatB_Yqey PF02637.13 ETS82230.1 - 0.05 13.3 1.3 0.093 12.4 0.9 1.5 1 1 0 1 1 1 0 GatB domain Yae1_N PF09811.4 ETS82232.1 - 3.8e-05 23.1 11.0 7.6e-05 22.1 7.6 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Trns_repr_metal PF02583.12 ETS82232.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor tRNA-synt_1g PF09334.6 ETS82233.1 - 1.4e-140 468.4 0.0 1.8e-140 468.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 ETS82233.1 - 8.9e-06 23.9 5.0 0.00074 17.6 0.0 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) PAH PF02671.16 ETS82233.1 - 0.14 11.8 0.1 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat RNase_H2-Ydr279 PF09468.5 ETS82233.1 - 0.27 10.4 4.4 0.4 9.8 3.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 ETS82233.1 - 0.77 9.4 8.7 1.7 8.2 6.0 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Atrophin-1 PF03154.10 ETS82233.1 - 1.7 6.6 6.5 2.4 6.1 4.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3043 PF11241.3 ETS82233.1 - 2 7.9 8.4 3.2 7.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Glyco_hydro_92 PF07971.7 ETS82234.1 - 6.4e-151 503.4 0.0 8.3e-151 503.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Nucleopor_Nup85 PF07575.8 ETS82235.1 - 4.9e-05 21.7 1.4 0.019 13.1 0.0 3.1 4 0 0 4 4 4 2 Nup85 Nucleoporin Upf2 PF04050.9 ETS82235.1 - 1.3 8.7 27.3 2.8 7.6 18.9 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Mpp10 PF04006.7 ETS82235.1 - 2.6 6.3 32.4 4 5.6 22.4 1.1 1 0 0 1 1 1 0 Mpp10 protein ADH_N PF08240.7 ETS82236.1 - 4.5e-28 97.1 2.1 1.2e-27 95.8 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82236.1 - 1.3e-17 63.5 0.2 2.4e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 ETS82236.1 - 0.03 13.7 0.3 0.05 12.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 ETS82236.1 - 0.13 12.1 1.0 3.1 7.6 0.7 2.3 2 0 0 2 2 2 0 ThiF family zf-AN1 PF01428.11 ETS82237.1 - 5.3e-11 42.1 14.4 7.4e-11 41.7 10.0 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger IGFBP PF00219.13 ETS82237.1 - 0.49 10.9 7.5 0.71 10.4 5.2 1.2 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Transp_Tc5_C PF04236.10 ETS82237.1 - 0.67 10.2 5.2 1.3 9.2 3.6 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C3HC4_3 PF13920.1 ETS82237.1 - 2.6 7.7 7.2 1.8 8.2 2.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CD45 PF12567.3 ETS82237.1 - 5.7 6.8 6.0 5.4 6.9 0.7 2.2 1 1 1 2 2 2 0 Leukocyte receptor CD45 HhH-GPD PF00730.20 ETS82238.1 - 2.4e-19 69.6 0.0 4.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS82238.1 - 1.2e-06 27.8 0.0 3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF676 PF05057.9 ETS82239.1 - 2.9e-53 180.4 0.0 4.4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 ETS82239.1 - 1.3e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82239.1 - 8.8e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS82239.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 ETS82239.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RNase_T PF00929.19 ETS82240.1 - 1.2e-06 28.9 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 ETS82240.1 - 0.0099 16.1 3.5 0.022 14.9 2.4 1.6 1 1 0 1 1 1 1 CHORD BTK PF00779.14 ETS82240.1 - 0.085 12.4 2.9 0.17 11.4 2.0 1.5 1 0 0 1 1 1 0 BTK motif zf-CCCH_2 PF14608.1 ETS82240.1 - 0.23 11.5 5.5 0.46 10.5 3.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Herpes_BLLF1 PF05109.8 ETS82240.1 - 1.2 7.0 23.1 1.8 6.4 16.0 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF952 PF06108.7 ETS82241.1 - 4.9e-14 51.9 0.0 6.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mito_fiss_reg PF05308.6 ETS82242.1 - 0.055 12.8 0.1 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CASP_C PF08172.7 ETS82242.1 - 1.1 8.2 4.2 1.2 8.1 1.5 1.9 1 1 0 1 1 1 0 CASP C terminal Pox_A_type_inc PF04508.7 ETS82242.1 - 3.5 7.6 6.0 62 3.7 0.0 3.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 ETS82242.1 - 5.8 6.4 6.3 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 IncA protein MMR_HSR1_C PF08438.5 ETS82243.1 - 2.7e-27 95.1 0.0 5.6e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 ETS82243.1 - 6.9e-15 55.0 0.0 1.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS82243.1 - 2.1e-07 30.3 0.1 0.00019 20.7 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETS82243.1 - 0.0004 19.8 0.1 0.34 10.3 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETS82243.1 - 0.0096 16.2 0.0 0.062 13.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 ETS82243.1 - 0.024 14.4 0.1 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 ETS82243.1 - 0.074 11.8 0.1 0.14 10.8 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 ETS82243.1 - 0.08 12.0 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Dioxygenase_C PF00775.16 ETS82244.1 - 1.6e-12 47.0 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase SET PF00856.23 ETS82245.1 - 0.0081 16.4 0.1 0.053 13.8 0.1 2.2 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.13 ETS82246.1 - 1e-33 116.3 1.5 2.1e-33 115.3 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82246.1 - 2.4e-10 40.1 11.1 4.3e-10 39.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDPD PF03009.12 ETS82247.1 - 5.2e-30 104.7 0.0 9.2e-30 103.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.27 ETS82248.1 - 1e-44 148.8 28.5 1.2e-09 37.6 0.2 10.5 10 0 0 10 10 10 8 WD domain, G-beta repeat DUF1513 PF07433.6 ETS82248.1 - 0.022 13.6 6.3 0.086 11.7 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF1513) Glyoxalase_4 PF13669.1 ETS82248.1 - 0.025 14.5 0.0 0.29 11.1 0.0 2.4 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily IRF PF00605.12 ETS82248.1 - 0.076 12.7 0.3 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor CPSF_A PF03178.10 ETS82248.1 - 0.079 12.0 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 CPSF A subunit region Proteasome_A_N PF10584.4 ETS82248.1 - 0.46 9.8 0.0 0.46 9.8 0.0 3.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature HET PF06985.6 ETS82249.1 - 6.6e-09 36.0 0.0 1.6e-06 28.3 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_tran_28_C PF04101.11 ETS82250.1 - 5.3e-17 61.9 0.0 3.2e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.4 ETS82251.1 - 1.7e-44 150.9 0.7 4.1e-44 149.7 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein V_ATPase_I PF01496.14 ETS82251.1 - 0.22 9.3 0.6 0.32 8.7 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_hydro_71 PF03659.9 ETS82253.1 - 4.3e-115 384.2 5.9 5.3e-115 383.9 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 VWA_2 PF13519.1 ETS82253.1 - 0.0018 18.4 0.2 0.0044 17.1 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain adh_short PF00106.20 ETS82254.1 - 4.5e-30 104.7 0.0 6.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82254.1 - 1.3e-25 90.5 0.2 1.3e-23 84.0 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82254.1 - 5.6e-13 48.9 0.0 7.7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82254.1 - 0.00094 18.6 0.1 0.0077 15.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family STAS PF01740.16 ETS82254.1 - 0.048 13.0 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 STAS domain Eno-Rase_NADH_b PF12242.3 ETS82254.1 - 0.066 13.0 0.5 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acetyltransf_1 PF00583.19 ETS82255.1 - 6.4e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS82255.1 - 5.1e-07 29.3 0.1 8.5e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS82255.1 - 0.0004 20.4 0.0 0.0023 18.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS82255.1 - 0.0053 16.8 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS82255.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS82255.1 - 0.027 14.3 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS82255.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.1 ETS82256.1 - 0.00019 21.4 0.6 0.00053 20.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 ETS82256.1 - 0.0037 16.6 20.5 0.0037 16.6 14.2 3.2 4 1 1 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal IF-2B PF01008.12 ETS82257.1 - 6.6e-31 107.3 0.0 9.7e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.13 ETS82258.1 - 7.5e-52 175.1 0.0 1.2e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.5 ETS82259.1 - 6.7e-23 81.0 2.4 7.6e-23 80.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.21 ETS82260.1 - 1.9e-20 72.1 0.5 8.5e-20 70.0 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FancD2 PF14631.1 ETS82260.1 - 6 3.8 7.6 7.3 3.5 5.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease ERG4_ERG24 PF01222.12 ETS82261.1 - 4.8e-141 470.1 19.3 5.6e-141 469.9 13.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1793 PF08760.6 ETS82263.1 - 9e-65 217.6 0.1 1.7e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Ribosomal_L18p PF00861.17 ETS82265.1 - 1.9e-43 147.4 0.2 3.4e-43 146.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 ETS82265.1 - 3.1e-33 114.2 8.2 3.1e-33 114.2 5.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region FKBP_N PF01346.13 ETS82265.1 - 0.1 12.6 3.3 0.37 10.8 2.0 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HAD_2 PF13419.1 ETS82266.1 - 4.3e-18 66.1 0.0 1.3e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS82266.1 - 0.00045 19.8 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 ETS82266.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Nucleoporin_FG PF13634.1 ETS82267.1 - 0.1 12.8 1.6 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin FG repeat region FAD_binding_3 PF01494.14 ETS82269.1 - 1.4e-19 70.3 0.8 3.3e-11 42.8 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS82269.1 - 2.3e-05 23.4 0.0 0.00033 19.6 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS82269.1 - 5.8e-05 23.0 0.0 0.00016 21.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS82269.1 - 0.0021 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS82269.1 - 0.024 14.7 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2063 PF09836.4 ETS82269.1 - 0.056 13.4 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) Pyr_redox PF00070.22 ETS82269.1 - 0.11 12.9 0.1 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ArfGap PF01412.13 ETS82270.1 - 1.7e-39 134.2 0.2 1.7e-39 134.2 0.1 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 ETS82270.1 - 0.012 15.4 0.1 0.054 13.3 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Dynamin_N PF00350.18 ETS82271.1 - 7.1e-12 45.4 0.0 4e-11 43.0 0.0 2.4 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 ETS82271.1 - 2.9e-05 23.3 0.1 0.00069 18.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS82271.1 - 0.0001 22.2 0.1 0.011 15.6 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETS82271.1 - 0.0012 19.1 0.1 0.0084 16.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETS82271.1 - 0.0019 18.1 1.9 0.0078 16.2 0.0 2.9 4 0 0 4 4 4 1 AAA ATPase domain Baculo_PEP_C PF04513.7 ETS82271.1 - 0.0077 16.0 5.8 1 9.1 0.2 3.5 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A3L PF05288.6 ETS82271.1 - 0.01 15.5 0.4 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Poxvirus A3L Protein AAA_23 PF13476.1 ETS82271.1 - 0.015 15.6 1.2 8.8 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain QueF PF14489.1 ETS82271.1 - 0.039 13.8 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 QueF-like protein AAA_22 PF13401.1 ETS82271.1 - 0.048 13.8 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain TraB PF01963.12 ETS82271.1 - 0.13 11.6 1.3 0.28 10.6 0.9 1.4 1 0 0 1 1 1 0 TraB family DUF1664 PF07889.7 ETS82271.1 - 0.21 11.3 5.4 1.1 9.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.1 ETS82271.1 - 0.42 10.5 7.7 0.86 9.5 3.3 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Methyltransf_23 PF13489.1 ETS82272.1 - 9e-16 58.0 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82272.1 - 2.4e-06 27.2 0.0 1.7e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS82272.1 - 5.4e-06 26.8 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82272.1 - 3.4e-05 24.3 0.0 0.00046 20.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS82272.1 - 0.052 12.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS82272.1 - 0.14 11.1 0.0 0.4 9.7 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pyridoxal_deC PF00282.14 ETS82273.1 - 7.9e-27 93.6 0.0 1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 ETS82273.1 - 1.2e-05 24.6 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 ETS82273.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2462 PF09495.5 ETS82274.1 - 1.2e-11 45.1 9.7 1.2e-11 45.1 6.7 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) FCH PF00611.18 ETS82275.1 - 9.9e-24 83.3 0.1 9.9e-24 83.3 0.0 3.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 ETS82275.1 - 1.8e-19 69.0 0.5 3.9e-12 45.5 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 ETS82275.1 - 1.1e-16 59.9 0.1 1.7e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 ETS82275.1 - 1.4e-14 53.5 5.6 2.2e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 ETS82275.1 - 3.4e-05 23.2 0.1 0.08 12.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 ETS82275.1 - 4.4e-05 23.5 0.6 0.0045 17.1 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Ax_dynein_light PF10211.4 ETS82275.1 - 0.0068 16.2 9.8 0.0068 16.2 6.8 2.2 2 0 0 2 2 2 1 Axonemal dynein light chain 7TM_GPCR_Sri PF10327.4 ETS82275.1 - 0.36 9.7 0.1 0.54 9.1 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri C1_2 PF03107.11 ETS82275.1 - 0.59 10.3 7.8 0.98 9.5 5.4 1.3 1 0 0 1 1 1 0 C1 domain YlqD PF11068.3 ETS82275.1 - 4.9 7.1 20.2 3.1 7.8 5.9 3.2 2 1 1 3 3 3 0 YlqD protein DEAD PF00270.24 ETS82276.1 - 2.2e-33 115.1 0.8 1.9e-32 112.1 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS82276.1 - 2.8e-22 78.3 0.0 5.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS82276.1 - 0.00017 21.4 0.0 0.00065 19.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 ETS82276.1 - 0.00031 20.4 0.0 0.0081 15.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS82276.1 - 0.0014 18.2 0.1 0.0036 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS82276.1 - 0.0066 16.0 0.4 0.81 9.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS82276.1 - 0.016 15.3 0.7 0.41 10.8 0.4 2.8 2 1 0 2 2 2 0 AAA domain RnfC_N PF13375.1 ETS82276.1 - 0.053 13.2 0.3 0.2 11.3 0.1 1.9 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Helicase_C_2 PF13307.1 ETS82276.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain VBS PF08913.5 ETS82276.1 - 0.078 13.2 0.5 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 Vinculin Binding Site DUF2075 PF09848.4 ETS82276.1 - 0.089 11.7 0.1 0.2 10.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CFEM PF05730.6 ETS82277.1 - 0.0019 17.9 6.8 0.0034 17.1 4.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF2207 PF09972.4 ETS82277.1 - 0.021 13.4 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_transf_90 PF05686.7 ETS82278.1 - 5.9e-17 61.4 0.0 3e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Spo7_2_N PF15407.1 ETS82278.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 SHNi-TPR PF10516.4 ETS82280.1 - 1.5e-13 49.7 0.6 1.5e-13 49.7 0.4 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 ETS82280.1 - 1.7e-09 37.4 9.0 0.00015 21.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS82280.1 - 1.5e-07 30.9 11.9 0.00011 21.7 0.3 3.5 3 1 1 4 4 4 3 TPR repeat Apc3 PF12895.2 ETS82280.1 - 1.3e-05 25.2 0.4 0.004 17.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS82280.1 - 1.4e-05 25.6 15.3 2.2e-05 24.9 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS82280.1 - 0.0052 16.6 18.1 0.23 11.4 1.4 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS82280.1 - 0.015 15.6 0.1 0.015 15.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 ETS82280.1 - 0.018 15.2 0.2 6.5 7.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS82280.1 - 0.04 13.5 7.5 0.16 11.5 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat IncA PF04156.9 ETS82280.1 - 0.14 11.6 8.5 0.18 11.3 0.1 2.7 1 1 0 2 2 2 0 IncA protein TPR_3 PF07720.7 ETS82280.1 - 0.31 10.8 8.6 0.037 13.8 2.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS82280.1 - 0.47 10.4 7.8 0.64 10.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS82280.1 - 0.5 11.1 11.5 2.4 9.0 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS82280.1 - 5.8 6.9 9.8 14 5.7 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CDC50 PF03381.10 ETS82281.1 - 1.2e-96 323.1 0.9 1.5e-96 322.8 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 ETS82281.1 - 0.23 11.6 1.3 5.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) MOSC PF03473.12 ETS82282.1 - 3.2e-19 68.7 0.0 8.1e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 MOSC domain NAD_binding_1 PF00175.16 ETS82282.1 - 8.6e-10 39.1 0.0 1e-08 35.6 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Fer2 PF00111.22 ETS82282.1 - 1.3e-09 37.6 0.7 3.3e-09 36.3 0.5 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.7 ETS82282.1 - 0.038 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain SNF2_N PF00176.18 ETS82283.1 - 3.3e-25 88.4 0.0 5.6e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS82283.1 - 3.9e-08 33.3 4.0 2.2e-07 30.8 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS82283.1 - 3.9e-05 23.4 0.1 9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Daxx PF03344.10 ETS82283.1 - 0.042 12.3 22.9 0.079 11.4 15.9 1.3 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 ETS82283.1 - 7.7 5.4 13.5 17 4.2 9.4 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_76 PF03663.9 ETS82284.1 - 2.5e-154 514.1 10.7 3.4e-154 513.6 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS82284.1 - 0.013 14.5 10.0 0.31 10.0 0.1 3.3 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 ETS82285.1 - 4.1e-29 101.3 67.8 7.4e-20 70.9 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS82285.1 - 0.00054 18.4 10.2 0.00054 18.4 7.1 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2388 PF09498.5 ETS82285.1 - 0.23 11.0 0.2 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Pro-kuma_activ PF09286.6 ETS82287.1 - 3e-47 160.2 0.1 1e-46 158.5 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS82287.1 - 6.2e-07 28.8 0.1 1.3e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.27 ETS82288.1 - 6.9e-49 162.0 16.3 2.1e-11 43.2 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 ETS82288.1 - 5.4e-06 24.8 2.4 0.11 10.6 0.0 4.3 3 1 0 4 4 4 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 ETS82288.1 - 0.016 13.4 0.0 0.033 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) HPS3_N PF14761.1 ETS82288.1 - 0.15 11.4 0.0 0.64 9.3 0.0 1.8 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 HEAT PF02985.17 ETS82289.1 - 1.2e-11 43.5 0.3 0.05 13.6 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 ETS82289.1 - 2.2e-08 33.6 0.0 3.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82289.1 - 9.3e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 ETS82289.1 - 0.00012 22.4 0.0 1.3 9.6 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 ETS82289.1 - 0.00024 21.3 0.0 0.0076 16.5 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 ETS82289.1 - 0.02 14.7 0.0 0.18 11.6 0.0 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETS82289.1 - 0.033 14.5 0.1 4.7 7.6 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 ETS82289.1 - 0.048 13.6 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 ETS82289.1 - 0.19 11.0 0.2 0.55 9.5 0.2 1.7 1 1 0 1 1 1 0 CLASP N terminal FAD_binding_4 PF01565.18 ETS82290.1 - 4.9e-23 81.1 1.3 8.3e-23 80.4 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain GHMP_kinases_N PF00288.21 ETS82291.1 - 9.2e-13 48.0 0.0 1.9e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 ETS82291.1 - 3.1e-05 24.0 0.0 7.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal 2OG-FeII_Oxy_3 PF13640.1 ETS82292.1 - 1.6e-11 44.5 0.0 4.2e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETS82292.1 - 0.00011 21.7 2.1 0.0039 16.7 0.1 2.9 2 1 1 3 3 3 2 2OG-Fe(II) oxygenase superfamily DUF2073 PF09846.4 ETS82292.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) Glyco_hydro_76 PF03663.9 ETS82293.1 - 5.5e-145 483.4 26.4 6.8e-145 483.0 18.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Pyr_redox_2 PF07992.9 ETS82294.1 - 6.4e-25 88.2 1.4 1e-24 87.5 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS82294.1 - 1.1e-15 57.8 1.5 2.5e-11 43.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 ETS82294.1 - 6.1e-14 51.3 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 ETS82294.1 - 5e-10 39.7 0.1 0.0003 20.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS82294.1 - 2e-09 36.8 0.5 0.023 13.6 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase Rieske_2 PF13806.1 ETS82294.1 - 2.1e-06 27.4 0.0 1.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 ETS82294.1 - 9.4e-06 24.7 0.0 0.077 11.8 0.0 2.5 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 ETS82294.1 - 9.5e-06 25.8 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 ETS82294.1 - 0.0025 17.5 1.9 0.45 10.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1188 PF06690.6 ETS82294.1 - 0.0076 15.4 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.1 ETS82294.1 - 0.01 16.1 0.8 0.29 11.4 0.0 2.5 1 1 1 2 2 2 1 Putative NAD(P)-binding Malic_M PF03949.10 ETS82294.1 - 0.028 13.9 0.2 0.062 12.8 0.1 1.6 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain TrkA_N PF02254.13 ETS82294.1 - 0.083 12.9 0.4 9.4 6.2 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.11 ETS82295.1 - 3.7e-43 147.5 24.0 3.7e-43 147.5 16.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily IncA PF04156.9 ETS82296.1 - 0.003 17.1 35.8 0.042 13.4 4.9 2.3 1 1 1 2 2 2 2 IncA protein Tropomyosin_1 PF12718.2 ETS82296.1 - 0.0032 17.3 25.7 0.0032 17.3 17.8 3.0 2 1 1 3 3 3 1 Tropomyosin like Bacillus_HBL PF05791.6 ETS82296.1 - 1.4 8.2 10.6 0.11 11.7 1.1 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.3 ETS82296.1 - 3.2 7.6 35.9 0.64 9.9 6.7 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding zf-C2H2_4 PF13894.1 ETS82297.1 - 2.7e-05 24.2 12.5 0.1 12.9 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS82297.1 - 0.0016 18.6 12.0 0.4 11.1 1.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type CENP-F_leu_zip PF10473.4 ETS82297.1 - 0.21 11.4 10.0 0.17 11.7 5.9 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Abhydrolase_3 PF07859.8 ETS82299.1 - 5e-36 124.2 0.1 7.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS82299.1 - 5.8e-06 25.3 0.0 9.8e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS82299.1 - 9.3e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETS82299.1 - 0.018 14.3 0.9 0.057 12.6 0.6 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase p450 PF00067.17 ETS82300.1 - 1.2e-33 116.4 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 ETS82301.1 - 4.9e-18 65.1 0.0 9.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS82301.1 - 1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS82301.1 - 2.9e-08 33.7 0.0 5.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 ETS82301.1 - 1.8e-05 24.6 0.0 8.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.1 ETS82301.1 - 7.4e-05 22.5 0.4 0.00013 21.8 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS82301.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP-grasp_3 PF02655.9 ETS82302.1 - 2.4e-07 30.7 0.0 4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS82302.1 - 4.9e-05 22.8 0.0 9.1e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 ETS82302.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 ETS82302.1 - 0.0031 16.9 0.0 0.0096 15.4 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.1 ETS82302.1 - 0.051 12.3 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.1 ETS82302.1 - 0.12 11.0 0.0 0.43 9.2 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon MFS_1 PF07690.11 ETS82303.1 - 1.4e-25 89.8 37.5 1.4e-25 89.8 26.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS82303.1 - 8.7e-05 21.0 21.4 0.0018 16.7 8.2 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 ETS82304.1 - 1.5e-31 109.3 32.9 1.5e-31 109.3 22.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS82304.1 - 0.073 12.5 3.4 0.19 11.2 2.3 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Rhomboid PF01694.17 ETS82305.1 - 5.9e-36 123.6 12.6 5.9e-36 123.6 8.7 2.2 2 0 0 2 2 2 1 Rhomboid family MFS_1 PF07690.11 ETS82306.1 - 2.1e-38 131.9 39.0 2.5e-38 131.7 27.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82306.1 - 2.4e-10 39.6 13.9 6.3e-10 38.2 9.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS82306.1 - 4.6e-06 25.1 1.4 4.6e-06 25.1 0.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS82306.1 - 6.3e-05 21.2 0.5 9.8e-05 20.6 0.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector EPSP_synthase PF00275.15 ETS82307.1 - 3.1e-129 431.0 0.0 4.7e-129 430.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 ETS82307.1 - 6.7e-101 336.6 0.0 1.1e-100 335.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 ETS82307.1 - 3.5e-61 206.7 0.0 5.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 ETS82307.1 - 3.7e-37 127.6 0.0 1.6e-35 122.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 ETS82307.1 - 2.5e-24 85.1 0.0 6.7e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS82307.1 - 1e-10 41.8 0.0 4.7e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 ETS82307.1 - 1.9e-08 33.9 0.0 4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 ETS82307.1 - 0.0017 19.1 0.0 0.0039 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS82307.1 - 0.084 12.8 0.0 0.33 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain zf-C2H2 PF00096.21 ETS82308.1 - 2.2e-09 37.1 13.0 0.018 15.3 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS82308.1 - 5.1e-06 26.4 15.5 0.0038 17.4 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 ETS82308.1 - 1.8 8.7 5.5 5 7.3 0.8 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAT1 PF09770.4 ETS82308.1 - 2.8 6.0 55.3 0.082 11.1 33.9 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Histone PF00125.19 ETS82309.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 ETS82309.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 ETS82309.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETS82309.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 ETS82309.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 ETS82309.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 ETS82310.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 ETS82310.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 ETS82310.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 ETS82310.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.12 ETS82311.1 - 5.5e-88 294.8 0.1 1.3e-87 293.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 ETS82311.1 - 3.1e-65 219.1 0.1 8e-65 217.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 ETS82311.1 - 2.4e-30 105.9 3.5 5.2e-22 78.5 0.0 3.5 3 2 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 ETS82311.1 - 1.1e-29 103.2 0.0 5e-29 101.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 ETS82311.1 - 8e-17 60.9 0.0 4.3e-16 58.5 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 ETS82312.1 - 6.4e-55 185.9 7.7 1.3e-54 184.9 5.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 ETS82312.1 - 5.2e-23 81.1 0.1 5.2e-23 81.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) GET2 PF08690.5 ETS82312.1 - 1.6 7.9 8.5 0.084 12.1 1.8 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 zf-C2H2 PF00096.21 ETS82313.1 - 1.9e-14 53.0 20.0 0.00011 22.3 0.5 3.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS82313.1 - 1.6e-09 37.4 17.7 0.0013 18.8 1.3 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS82313.1 - 2.9e-05 24.1 23.8 0.001 19.2 3.1 4.3 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS82313.1 - 0.041 14.0 13.5 0.43 10.7 1.2 4.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 ETS82313.1 - 0.068 12.9 12.2 0.43 10.3 5.2 2.7 2 1 1 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 ETS82313.1 - 0.35 10.5 5.2 0.2 11.3 1.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 ETS82313.1 - 0.61 9.6 3.4 21 4.7 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_2 PF12756.2 ETS82313.1 - 1.1 9.4 9.0 2.3 8.3 5.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 ETS82313.1 - 2.7 8.2 7.3 19 5.6 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 ETS82313.1 - 4.3 7.3 10.2 1 9.3 2.8 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Rep_fac-A_C PF08646.5 ETS82313.1 - 6.9 6.3 6.6 4.4 7.0 1.5 2.1 1 1 1 2 2 2 0 Replication factor-A C terminal domain DUF1227 PF06777.6 ETS82314.1 - 8.4e-61 203.9 1.1 2.4e-60 202.4 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 ETS82314.1 - 2.1e-51 173.8 0.4 4.4e-51 172.7 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 ETS82314.1 - 4.5e-44 150.3 0.7 2.2e-43 148.0 0.0 2.5 3 0 0 3 3 3 1 Helicase C-terminal domain SNF2_N PF00176.18 ETS82314.1 - 1.5e-05 23.9 0.0 5e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 ETS82314.1 - 0.0014 18.1 0.0 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 ETS82314.1 - 0.0034 17.2 0.8 0.0098 15.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS82314.1 - 0.03 14.4 0.1 2.5 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 ETS82314.1 - 0.14 11.7 5.6 0.033 13.7 0.3 2.4 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 ETS82315.1 - 6.3e-25 87.6 72.4 5.8e-17 61.4 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rossmann-like PF10727.4 ETS82315.1 - 0.0059 16.3 0.6 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 Rossmann-like domain Cupin_8 PF13621.1 ETS82316.1 - 5.6e-41 140.6 0.0 9.7e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 ETS82316.1 - 4.1e-21 75.3 0.1 8.2e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 ETS82316.1 - 1.2e-09 37.7 0.9 7.6e-05 22.3 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 ETS82316.1 - 1.1e-08 35.0 3.9 0.0011 19.0 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Cupin_4 PF08007.7 ETS82316.1 - 1.9e-05 24.0 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.1 ETS82316.1 - 0.0018 18.2 0.4 16 5.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 ETS82316.1 - 0.041 14.0 1.9 0.56 10.4 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DUF3903 PF13043.1 ETS82316.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) WD40 PF00400.27 ETS82317.1 - 4.3e-06 26.3 8.1 0.00013 21.7 0.0 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 ETS82317.1 - 0.00052 19.4 0.0 0.73 9.3 0.0 3.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.6 ETS82317.1 - 0.062 12.5 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split Myf5 PF12232.3 ETS82317.1 - 3 8.5 8.5 8.5 7.0 2.9 2.7 2 0 0 2 2 2 0 Myogenic determination factor 5 DSPc PF00782.15 ETS82318.1 - 8.9e-26 90.0 0.0 2e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS82318.1 - 0.00021 20.6 0.0 0.00099 18.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DDHD PF02862.12 ETS82319.1 - 1.3e-37 129.8 0.0 3.6e-34 118.5 0.0 2.8 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 ETS82319.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 ETS82319.1 - 0.0081 15.6 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 ETS82319.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Transket_pyr PF02779.19 ETS82320.1 - 1.4e-63 213.6 0.0 2.7e-63 212.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 ETS82320.1 - 1.7e-57 194.4 0.0 2.4e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 ETS82321.1 - 7.6e-23 79.9 0.0 1.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 ETS82321.1 - 2.5e-22 78.3 4.9 3.3e-13 49.1 0.1 3.0 3 0 0 3 3 3 2 BSD domain CysG_dimeriser PF10414.4 ETS82321.1 - 1.6 8.2 5.9 9.2 5.8 0.1 3.4 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Clp1 PF06807.9 ETS82322.1 - 1.7e-22 80.1 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 ETS82322.1 - 3.3e-09 36.5 0.0 7.4e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 ETS82322.1 - 0.00036 19.8 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 ETS82322.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 ETS82322.1 - 0.002 18.1 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 ETS82322.1 - 0.0025 17.1 0.2 0.0069 15.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 ETS82322.1 - 0.0034 16.9 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 ETS82322.1 - 0.0038 16.7 0.1 0.0073 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 ETS82322.1 - 0.016 14.4 0.0 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 ETS82322.1 - 0.019 14.5 0.1 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 ETS82322.1 - 0.036 14.5 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 ETS82322.1 - 0.053 12.9 0.0 0.18 11.2 0.0 1.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 ETS82322.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 ETS82322.1 - 0.074 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS82322.1 - 0.079 13.7 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 ETS82322.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 ETS82322.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPK PF03770.11 ETS82323.1 - 2.3e-50 170.9 0.0 3.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 ETS82324.1 - 9e-83 278.3 0.0 1.1e-82 277.9 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Mst1_SARAH PF11629.3 ETS82324.1 - 0.29 10.9 3.5 3 7.7 1.2 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Na_H_Exchanger PF00999.16 ETS82325.1 - 1.3e-37 129.3 20.1 1.7e-37 128.8 13.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 ETS82325.1 - 0.22 11.4 1.6 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 YrhC-like protein PepSY_TM_2 PF13703.1 ETS82325.1 - 0.54 10.4 0.1 0.54 10.4 0.0 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix Pyr_redox_2 PF07992.9 ETS82326.1 - 7.5e-19 68.3 0.0 9.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS82326.1 - 0.00036 19.4 0.1 0.019 13.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 ETS82326.1 - 0.00083 18.5 0.6 0.0016 17.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 ETS82326.1 - 0.0028 17.4 1.4 2.1 8.1 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS82326.1 - 0.031 14.3 2.5 2 8.3 1.4 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS82326.1 - 0.033 14.2 2.6 0.91 9.6 0.1 3.3 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS82326.1 - 0.034 12.6 0.2 0.32 9.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 ETS82326.1 - 0.062 12.3 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family muHD PF10291.4 ETS82327.1 - 8.1e-66 221.8 0.0 1.6e-65 220.8 0.0 1.5 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 ETS82327.1 - 2.5e-11 43.6 1.5 4.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cys_Met_Meta_PP PF01053.15 ETS82327.1 - 0.0064 14.8 0.1 0.014 13.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PhoU_div PF01865.11 ETS82327.1 - 0.076 12.1 0.2 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 OmpH PF03938.9 ETS82327.1 - 0.4 10.5 9.9 0.78 9.6 6.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IZUMO PF15005.1 ETS82327.1 - 2.3 8.2 3.3 1.2 9.1 0.7 1.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion Pkinase PF00069.20 ETS82328.1 - 1.1e-33 116.4 0.0 1.7e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82328.1 - 1.5e-11 43.8 0.0 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NmrA PF05368.8 ETS82329.1 - 6.3e-14 51.8 0.0 1.1e-13 51.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS82329.1 - 1.5e-12 47.9 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding CoA_binding_2 PF13380.1 ETS82329.1 - 0.051 13.7 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain 3HCDH_N PF02737.13 ETS82329.1 - 0.072 12.7 0.7 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amidohydro_4 PF13147.1 ETS82329.1 - 0.073 13.0 0.0 0.68 9.9 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase Epimerase PF01370.16 ETS82329.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HD_3 PF13023.1 ETS82331.1 - 1.2e-46 158.5 0.0 1.5e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 HD domain 2-Hacid_dh_C PF02826.14 ETS82332.1 - 1.3e-45 154.7 0.0 1.9e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS82332.1 - 4.2e-05 23.0 0.0 0.0001 21.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 ETS82332.1 - 0.0036 17.6 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_10 PF13460.1 ETS82332.1 - 0.0077 16.2 0.3 0.022 14.7 0.0 1.9 2 1 0 2 2 2 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 ETS82332.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 ETS82332.1 - 0.069 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 ETS82332.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 ETS82334.1 - 1.3e-20 74.3 0.0 4.8e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS82334.1 - 5.9e-17 61.0 0.1 8.2e-16 57.2 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS82334.1 - 2.9e-09 37.1 0.0 6.7e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS82334.1 - 7.2e-09 35.0 0.0 3e-06 26.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS82334.1 - 4.7e-08 32.9 0.7 6.6e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS82334.1 - 4.8e-07 29.0 0.1 1.5e-06 27.3 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS82334.1 - 1.6e-06 28.4 2.1 0.016 15.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS82334.1 - 7.8e-06 26.0 0.1 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETS82334.1 - 0.0013 18.4 0.2 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 ETS82334.1 - 0.016 13.6 0.8 0.28 9.5 0.3 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 ETS82334.1 - 0.026 14.8 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 ETS82334.1 - 0.031 13.8 0.1 9.6 5.7 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 ETS82334.1 - 0.047 12.8 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 ETS82334.1 - 0.051 12.4 2.0 0.071 11.9 0.7 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 ETS82334.1 - 0.13 12.0 1.7 0.56 9.9 0.1 2.6 4 0 0 4 4 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 ETS82334.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 ETS82334.1 - 0.42 9.4 0.9 1.1 8.0 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 ETS82334.1 - 0.55 9.5 2.8 0.39 10.0 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sas10_Utp3 PF04000.10 ETS82335.1 - 3.4e-16 59.2 2.7 6.6e-16 58.2 1.9 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.11 ETS82336.1 - 1.8e-195 650.3 4.4 2.3e-195 649.9 3.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 ETS82336.1 - 0.87 8.8 3.9 2.6 7.2 2.7 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family AAA PF00004.24 ETS82337.1 - 1e-15 58.0 0.0 1.7e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS82337.1 - 0.0017 18.4 0.0 0.009 16.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain CH PF00307.26 ETS82337.1 - 0.031 14.3 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain RNA_helicase PF00910.17 ETS82337.1 - 0.034 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 ETS82337.1 - 0.058 12.0 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AFG1_ATPase PF03969.11 ETS82337.1 - 0.058 12.1 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase T2SE PF00437.15 ETS82337.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 ETS82337.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain WSC PF01822.14 ETS82338.1 - 1.4e-09 37.6 11.3 1.4e-09 37.6 7.8 2.0 2 0 0 2 2 2 1 WSC domain Abhydrolase_5 PF12695.2 ETS82338.1 - 5.5e-05 22.9 0.1 0.00023 20.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82338.1 - 0.0027 17.5 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS82338.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 ETS82338.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1705 PF08019.7 ETS82339.1 - 5.2 6.5 13.1 2.4 7.6 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) Rieske PF00355.21 ETS82340.1 - 4.5e-12 45.3 0.0 7e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ETS82340.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ribosomal_S21 PF01165.15 ETS82341.1 - 7.1e-13 47.7 5.5 1.2e-12 47.0 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 ETS82342.1 - 1.9e-10 40.6 0.2 5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 ETS82342.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH PF00378.15 ETS82343.1 - 1.3e-44 152.1 0.0 5.5e-36 123.9 0.1 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS82343.1 - 0.12 12.1 0.1 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 HET PF06985.6 ETS82344.1 - 5.2e-34 117.3 2.3 7.5e-34 116.8 0.2 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS82344.1 - 1.2e-18 67.2 0.0 1.8e-14 53.8 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS82344.1 - 2.8e-14 52.7 0.1 6.1e-10 39.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS82344.1 - 1.8e-12 47.4 0.0 2.1e-07 31.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS82344.1 - 9.6e-12 44.0 0.0 3.9e-05 23.2 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 ETS82344.1 - 3.1e-09 36.1 0.0 0.0011 18.9 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat Glyco_hydro_28 PF00295.12 ETS82345.1 - 9.1e-41 139.8 2.2 1.2e-40 139.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_15 PF00723.16 ETS82347.1 - 1.3e-72 244.8 0.0 7e-58 196.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.14 ETS82347.1 - 6.3e-20 70.5 0.0 1.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Fringe PF02434.11 ETS82348.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Claudin_2 PF13903.1 ETS82349.1 - 0.00044 19.9 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TRM PF02005.11 ETS82350.1 - 3.8e-104 348.6 0.0 7.3e-90 301.5 0.0 2.7 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 ETS82350.1 - 2.4e-08 34.0 0.1 5.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82350.1 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 ETS82350.1 - 0.00074 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 ETS82350.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 ETS82350.1 - 0.0016 17.8 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 ETS82350.1 - 0.0041 17.6 0.0 0.0098 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS82350.1 - 0.027 13.6 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 ETS82350.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DAGK_cat PF00781.19 ETS82351.1 - 4.3e-06 26.1 0.1 1.8e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.22 ETS82352.1 - 6.5e-47 159.2 5.9 2.1e-22 79.8 0.1 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 ETS82352.1 - 3.7e-12 46.8 4.4 0.0006 19.8 0.0 4.5 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 ETS82352.1 - 1.4e-09 37.4 1.4 0.043 13.0 0.2 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS82352.1 - 1.7e-07 30.6 1.0 0.00021 20.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS82352.1 - 2e-06 27.9 0.2 0.17 12.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 ETS82352.1 - 6.6e-06 26.1 0.2 0.0021 18.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS82352.1 - 7.9e-06 25.8 0.0 0.047 13.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_2 PF12848.2 ETS82352.1 - 1e-05 25.3 6.0 1e-05 25.3 4.2 2.5 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 ETS82352.1 - 1.6e-05 25.6 6.4 0.0052 17.5 0.2 3.6 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 ETS82352.1 - 1.7e-05 24.0 1.3 0.043 12.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS82352.1 - 2.7e-05 24.0 0.6 0.0099 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 ETS82352.1 - 8e-05 23.1 1.1 0.34 11.4 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein NACHT PF05729.7 ETS82352.1 - 9.7e-05 22.0 0.1 0.04 13.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 ETS82352.1 - 0.0001 22.0 0.0 0.075 12.7 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS82352.1 - 0.00013 22.1 0.1 0.04 14.1 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETS82352.1 - 0.00015 21.3 3.1 0.069 12.7 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 ETS82352.1 - 0.00022 21.5 4.5 0.044 14.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 ETS82352.1 - 0.00026 19.8 1.9 0.3 9.8 0.3 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 ETS82352.1 - 0.00062 19.7 5.2 0.55 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 ETS82352.1 - 0.00085 18.4 6.4 0.018 14.0 0.1 4.0 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.17 ETS82352.1 - 0.0015 18.7 0.1 0.39 10.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 ETS82352.1 - 0.0015 18.3 0.1 0.68 9.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 ETS82352.1 - 0.0032 17.3 9.6 0.32 10.7 0.4 3.4 3 0 0 3 3 3 2 Domain of unknown function DUF87 DUF815 PF05673.8 ETS82352.1 - 0.0042 16.0 3.4 0.37 9.6 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETS82352.1 - 0.0071 16.2 0.2 0.71 9.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 ETS82352.1 - 0.012 15.1 4.9 1.4 8.2 0.2 3.1 3 1 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 ETS82352.1 - 0.014 14.8 1.8 0.057 12.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 ETS82352.1 - 0.016 14.9 0.5 1.7 8.3 0.0 2.9 3 0 0 3 3 2 0 NTPase Dynamin_N PF00350.18 ETS82352.1 - 0.016 15.0 4.5 0.12 12.1 0.1 3.1 3 0 0 3 3 3 0 Dynamin family AAA_19 PF13245.1 ETS82352.1 - 0.023 14.4 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 ETS82352.1 - 0.023 14.3 2.3 0.66 9.6 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase NYN PF01936.13 ETS82352.1 - 0.026 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 NYN domain ATP-synt_ab PF00006.20 ETS82352.1 - 0.032 13.7 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 ETS82352.1 - 0.034 12.7 0.0 0.034 12.7 0.0 2.5 3 0 0 3 3 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 ETS82352.1 - 0.05 13.3 0.2 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 ETS82352.1 - 0.053 13.8 21.7 1.8 8.8 5.3 4.0 3 1 0 3 3 3 0 AAA domain Arf PF00025.16 ETS82352.1 - 0.073 12.3 0.8 1.5 8.0 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 ETS82352.1 - 0.13 11.7 1.5 5.4 6.4 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 ETS82352.1 - 0.18 11.2 3.8 0.26 10.7 0.3 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family KAP_NTPase PF07693.9 ETS82352.1 - 0.45 9.4 4.9 5.5 5.8 0.0 3.4 2 1 0 2 2 2 0 KAP family P-loop domain Thymidylate_kin PF02223.12 ETS82352.1 - 0.48 9.7 8.2 9 5.6 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase SET PF00856.23 ETS82353.1 - 1.3e-10 41.8 0.2 6e-10 39.6 0.0 2.1 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.1 ETS82353.1 - 0.033 14.1 1.5 0.067 13.1 1.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SAF PF08666.7 ETS82353.1 - 0.11 12.8 0.1 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 SAF domain Sugar_tr PF00083.19 ETS82354.1 - 4.7e-120 401.2 33.8 5.4e-120 401.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82354.1 - 9.5e-22 77.1 41.7 1.4e-21 76.5 26.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS82354.1 - 0.00038 18.8 3.0 0.00038 18.8 2.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cupin_1 PF00190.17 ETS82355.1 - 1.8e-14 53.4 0.3 2.4e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ETS82355.1 - 0.0078 15.6 0.1 0.048 13.1 0.1 2.0 1 1 0 1 1 1 1 Cupin domain SUN PF03856.8 ETS82356.1 - 9e-72 241.3 10.5 9e-72 241.3 7.3 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) PCI PF01399.22 ETS82357.1 - 0.0091 16.3 0.0 4.3 7.6 0.0 2.7 2 0 0 2 2 2 2 PCI domain TPR_2 PF07719.12 ETS82357.1 - 0.016 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS82358.1 - 2.3e-43 148.2 32.3 2.3e-43 148.2 22.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82358.1 - 9e-13 47.5 24.0 2e-12 46.4 8.5 2.7 1 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 ETS82358.1 - 2.2e-11 42.7 3.7 3.4e-11 42.0 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3611 PF12263.3 ETS82358.1 - 0.0038 16.6 6.8 0.6 9.4 0.7 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3611) Thiolase_N PF00108.18 ETS82359.1 - 9.5e-94 313.2 0.3 1.4e-93 312.7 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 ETS82359.1 - 5.9e-37 125.8 0.8 5.9e-37 125.8 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 ETS82359.1 - 0.00016 21.2 0.2 0.00042 19.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_23 PF13489.1 ETS82360.1 - 1.9e-13 50.4 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82360.1 - 1.9e-06 27.5 0.0 6.1e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82360.1 - 0.00061 20.3 0.0 0.0048 17.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS82360.1 - 0.0037 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS82360.1 - 0.015 15.6 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UQ_con PF00179.21 ETS82361.1 - 1.4e-51 173.5 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS82361.1 - 8.2e-07 28.8 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS82361.1 - 0.031 14.1 0.1 0.062 13.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 ETS82362.1 - 7.1e-111 370.1 0.2 7.1e-111 370.1 0.2 2.1 2 0 0 2 2 2 1 Kinesin motor domain AAA_10 PF12846.2 ETS82362.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.8 2 1 0 2 2 2 0 AAA-like domain RolB_RolC PF02027.12 ETS82362.1 - 4.1 6.5 6.6 2.8 7.0 0.7 2.5 2 0 0 2 2 2 0 RolB/RolC glucosidase family TFIID-18kDa PF02269.11 ETS82363.1 - 4.3e-30 103.3 1.0 3e-29 100.6 0.1 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 ETS82363.1 - 0.008 15.3 0.8 0.014 14.5 0.5 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Ribonuc_L-PSP PF01042.16 ETS82363.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP Ribosomal_60s PF00428.14 ETS82363.1 - 4.9 7.6 7.7 1 9.8 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LCM PF04072.9 ETS82364.1 - 7.2e-22 77.8 0.0 2.5e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase UPF0259 PF06790.6 ETS82365.1 - 0.016 14.6 0.2 0.016 14.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) Gemini_mov PF01708.11 ETS82365.1 - 1.6 8.3 12.7 0.15 11.6 0.4 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF2422 PF10337.4 ETS82366.1 - 3.4e-22 78.8 19.7 3.8e-15 55.6 0.2 3.7 2 2 2 4 4 4 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 ETS82366.1 - 2.2e-10 40.5 13.3 2.2e-10 40.5 9.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 ETS82366.1 - 2.4e-10 39.6 6.0 2.4e-10 39.6 4.2 3.2 3 1 0 3 3 3 1 Aluminium activated malate transporter DUF2421 PF10334.4 ETS82366.1 - 3.3e-05 23.6 0.1 6.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Cwf_Cwc_15 PF04889.7 ETS82366.1 - 0.097 12.3 0.1 0.097 12.3 0.1 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Tom37_C PF11801.3 ETS82366.1 - 0.33 10.8 1.2 1 9.2 0.9 1.8 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 ETS82366.1 - 4.5 5.1 15.5 0.0053 14.8 3.1 1.6 2 0 0 2 2 2 0 CDC45-like protein Ist1 PF03398.9 ETS82367.1 - 4.8e-67 224.4 1.0 6e-67 224.1 0.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_2 PF13696.1 ETS82368.1 - 0.015 14.7 12.6 0.047 13.1 1.9 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 ETS82368.1 - 0.049 13.3 0.4 0.049 13.3 0.3 2.9 2 0 0 2 2 2 0 Zinc knuckle Clat_adaptor_s PF01217.15 ETS82369.1 - 2.7e-43 147.0 2.6 3.3e-43 146.8 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Baculo_VP39 PF04501.7 ETS82369.1 - 0.025 13.5 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 adh_short PF00106.20 ETS82370.1 - 6.3e-11 42.4 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82370.1 - 0.00015 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 ETS82371.1 - 6.4e-40 136.9 28.2 6.4e-40 136.9 19.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS82372.1 - 1.4e-16 60.1 0.1 2.2e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HHH_3 PF12836.2 ETS82372.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif FAA_hydrolase PF01557.13 ETS82373.1 - 3.5e-62 209.7 0.0 4.2e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Clr2 PF10383.4 ETS82374.1 - 1.1e-10 41.5 0.0 2.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 TFIIA PF03153.8 ETS82374.1 - 8.4 6.1 7.7 13 5.5 5.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_RNApol_7kD PF03604.8 ETS82375.1 - 0.0054 16.1 2.3 0.0054 16.1 1.6 4.9 4 2 0 4 4 4 1 DNA directed RNA polymerase, 7 kDa subunit FYVE_2 PF02318.11 ETS82375.1 - 0.012 15.5 27.7 0.58 10.0 1.5 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger Sar8_2 PF03058.9 ETS82375.1 - 2.1 8.7 11.5 0.96 9.8 0.1 3.1 3 0 0 3 3 3 0 Sar8.2 family DAO PF01266.19 ETS82376.1 - 7.9e-29 100.6 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS82376.1 - 0.00025 20.9 0.5 0.001 19.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS82376.1 - 0.0026 16.9 0.2 0.0058 15.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS82376.1 - 0.022 15.1 0.0 0.079 13.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS82376.1 - 0.033 13.0 0.0 0.068 12.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain ALG3 PF05208.8 ETS82377.1 - 6.3e-142 473.1 18.7 7.4e-142 472.9 13.0 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 ETS82378.1 - 1.2e-16 59.8 0.1 1.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RGS PF00615.14 ETS82379.1 - 1.6e-34 118.5 0.0 4.3e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 ETS82379.1 - 6.5e-21 73.8 0.1 1.8e-17 62.8 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BAF1_ABF1 PF04684.8 ETS82381.1 - 4.1 6.1 19.5 6.6 5.4 13.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ORC4_C PF14629.1 ETS82382.1 - 1.2e-59 201.1 0.0 1.7e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 ETS82382.1 - 3.8e-15 56.3 0.2 5.1e-14 52.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain PHD PF00628.24 ETS82382.1 - 1.4e-10 40.6 7.2 2.6e-10 39.8 5.0 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 ETS82382.1 - 1.7e-07 31.4 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS82382.1 - 1.7e-07 31.5 0.0 4.5e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PHD_2 PF13831.1 ETS82382.1 - 9e-07 28.1 2.4 1.7e-06 27.2 1.7 1.5 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.7 ETS82382.1 - 4.3e-05 23.2 0.1 0.00019 21.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 ETS82382.1 - 0.00071 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.1 ETS82382.1 - 0.0022 17.6 0.0 0.0065 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS82382.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS82382.1 - 0.003 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase C1_1 PF00130.17 ETS82382.1 - 0.0032 17.1 1.5 0.0032 17.1 1.0 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ATP-synt_ab PF00006.20 ETS82382.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 ETS82382.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETS82382.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Prok-RING_1 PF14446.1 ETS82382.1 - 0.06 13.0 2.3 0.13 12.0 1.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FtsK_SpoIIIE PF01580.13 ETS82382.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 ETS82382.1 - 0.086 13.0 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase zf-RING_2 PF13639.1 ETS82382.1 - 3.3 7.6 6.6 3.2 7.6 1.7 2.3 1 1 1 2 2 2 0 Ring finger domain Pkinase PF00069.20 ETS82383.1 - 4.9e-63 212.7 0.0 1e-62 211.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82383.1 - 1.5e-35 122.5 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 ETS82383.1 - 3e-29 100.5 15.0 2.6e-16 59.1 4.0 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 ETS82383.1 - 3e-19 68.4 30.8 2.6e-11 43.0 7.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 ETS82383.1 - 6.3e-14 52.2 2.3 6.3e-14 52.2 1.6 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS82383.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PHD PF00628.24 ETS82383.1 - 7.5 6.3 28.9 0.12 12.0 5.8 2.4 2 0 0 2 2 2 0 PHD-finger She9_MDM33 PF05546.6 ETS82384.1 - 8.6e-82 273.7 1.9 1.3e-81 273.1 1.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 ETS82384.1 - 0.058 12.9 1.4 0.11 12.1 1.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein HAD PF12710.2 ETS82385.1 - 3.5e-13 50.1 0.0 4.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS82385.1 - 0.00017 21.8 0.0 0.00039 20.6 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS82385.1 - 0.0037 17.7 0.2 0.042 14.2 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 ETS82385.1 - 0.014 14.5 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase SpoU_methylas_C PF12105.3 ETS82385.1 - 0.014 14.9 0.0 0.073 12.6 0.0 2.0 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal UMPH-1 PF05822.7 ETS82385.1 - 0.045 13.0 0.1 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) CDC73 PF05179.9 ETS82386.1 - 9.5e-48 162.9 0.0 1.7e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family TAP42 PF04177.7 ETS82387.1 - 2.2e-102 342.4 0.4 2.5e-102 342.3 0.3 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.21 ETS82388.1 - 3.8e-39 133.6 0.0 9.7e-21 74.3 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 ETS82388.1 - 2.2e-24 85.8 0.1 8.8e-10 38.6 0.0 4.4 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 ETS82388.1 - 1.2e-19 69.8 0.1 5.7e-19 67.6 0.1 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 ETS82388.1 - 1.7e-16 59.8 0.0 7.6e-16 57.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS82388.1 - 4.4e-13 49.4 0.1 1.8e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS82388.1 - 1.4e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS82388.1 - 0.0055 16.8 0.2 0.034 14.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 ETS82388.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CLASP_N PF12348.3 ETS82390.1 - 9.3e-124 411.1 1.4 3.5e-86 288.2 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 ETS82390.1 - 0.0015 18.4 0.1 0.53 10.4 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 ETS82390.1 - 0.0022 18.2 1.2 0.18 12.0 0.0 4.2 3 2 1 4 4 4 1 HEAT repeats DUF2999 PF11212.3 ETS82390.1 - 0.1 12.6 0.1 0.43 10.6 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) BSP PF04450.7 ETS82391.1 - 1.3e-68 230.4 0.0 1.7e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 ETS82391.1 - 2.2e-07 30.9 0.3 0.0001 22.3 0.0 2.3 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 ETS82391.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M43 PF05572.8 ETS82391.1 - 0.049 13.2 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Iso_dh PF00180.15 ETS82394.1 - 9e-101 337.2 0.0 1.1e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 ETS82395.1 - 4.4e-37 127.5 0.0 1.5e-36 125.8 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 ETS82395.1 - 0.0006 19.5 2.3 0.00088 19.0 0.1 2.5 3 0 0 3 3 3 1 Vps51/Vps67 NBP1 PF08537.5 ETS82396.1 - 0.14 11.3 0.8 0.14 11.3 0.5 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 zf-BED PF02892.10 ETS82397.1 - 0.012 15.3 0.2 0.012 15.3 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 ETS82397.1 - 0.076 12.9 7.6 0.17 11.8 5.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 ETS82397.1 - 0.18 11.7 2.7 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_92 PF07971.7 ETS82398.1 - 3.7e-156 520.6 3.0 4.9e-156 520.3 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 ETS82398.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 ETS82399.1 - 2.7e-15 55.9 0.0 1e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82399.1 - 2.2e-07 30.6 11.5 3.8e-07 29.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MtrG PF04210.8 ETS82399.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G adh_short PF00106.20 ETS82400.1 - 1.6e-09 37.9 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS82400.1 - 1.5e-05 24.5 0.0 2.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS82400.1 - 0.00011 22.3 0.1 0.0016 18.4 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS82400.1 - 0.012 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 ETS82400.1 - 0.033 14.2 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 ETS82400.1 - 0.042 12.7 0.1 0.1 11.5 0.1 1.8 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 ETS82400.1 - 0.094 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 ETS82400.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.5 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF822 PF05687.8 ETS82400.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Abhydrolase_6 PF12697.2 ETS82401.1 - 9e-18 64.9 2.3 1.3e-17 64.5 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82401.1 - 1.6e-08 34.4 0.0 5.6e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS82401.1 - 0.0032 16.7 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETS82401.1 - 0.0073 15.8 0.3 0.032 13.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Phosphorylase PF00343.15 ETS82402.1 - 0 1078.5 1.1 0 1078.2 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.15 ETS82403.1 - 1.6e-117 392.5 0.0 1.8e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 ETS82403.1 - 4.5e-11 42.2 0.3 6.8e-10 38.4 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 ETS82403.1 - 0.014 15.8 0.0 11 6.5 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein SH3_9 PF14604.1 ETS82404.1 - 3.7e-07 29.6 0.5 7.4e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS82404.1 - 0.0011 18.4 0.2 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS82404.1 - 0.45 9.9 2.7 0.88 9.0 1.8 1.5 1 0 0 1 1 1 0 SH3 domain Pex2_Pex12 PF04757.9 ETS82405.1 - 2.3e-58 197.3 1.2 2.9e-58 196.9 0.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 ETS82405.1 - 5.6e-05 23.0 3.1 0.0001 22.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS82405.1 - 0.00049 19.9 2.0 0.0008 19.2 1.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETS82405.1 - 0.00056 19.6 2.0 0.0009 19.0 1.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS82405.1 - 0.012 15.2 0.5 0.021 14.4 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS82405.1 - 0.11 12.1 3.1 0.2 11.3 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glycos_transf_2 PF00535.21 ETS82406.1 - 1.2e-25 90.1 0.0 2.1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 ETS82406.1 - 2.1e-11 44.0 0.4 7e-08 32.5 0.0 3.0 3 1 1 4 4 4 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 ETS82406.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 ETS82406.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 SE PF08491.5 ETS82407.1 - 7.3e-90 300.5 0.0 9.1e-90 300.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 ETS82407.1 - 3.7e-10 39.3 0.0 6.7e-05 22.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS82407.1 - 2.2e-09 36.6 0.3 4.5e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS82407.1 - 1e-06 28.0 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETS82407.1 - 1.5e-06 28.0 0.1 3.6e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS82407.1 - 3.4e-05 22.8 0.0 0.00034 19.5 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS82407.1 - 5.8e-05 22.3 2.7 0.00024 20.2 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS82407.1 - 8.6e-05 21.5 0.4 0.00017 20.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS82407.1 - 0.00024 21.0 0.2 0.00047 20.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS82407.1 - 0.0048 17.0 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 ETS82407.1 - 0.0055 15.6 0.1 0.079 11.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS82407.1 - 0.011 14.2 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 ETS82407.1 - 0.013 14.9 0.1 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 ETS82407.1 - 0.015 15.6 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS82407.1 - 0.062 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 ETS82407.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 ETS82407.1 - 0.2 10.2 0.1 1.5 7.3 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Mito_carr PF00153.22 ETS82409.1 - 3.5e-62 206.1 1.5 2.5e-20 71.9 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 ETS82410.1 - 7.9e-06 25.4 0.1 3.4e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 ETS82410.1 - 0.0067 15.9 0.0 0.35 10.4 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Glyco_transf_15 PF01793.11 ETS82411.1 - 8.5e-143 475.2 3.9 1e-142 475.0 2.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 ETS82411.1 - 0.0079 15.9 0.7 0.026 14.2 0.5 1.9 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor PAT1 PF09770.4 ETS82412.1 - 3.6e-234 779.6 16.7 4.3e-234 779.3 11.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sin_N PF04801.8 ETS82413.1 - 4.6e-20 71.8 0.1 1.6e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region SH3_9 PF14604.1 ETS82414.1 - 1e-08 34.6 2.7 6.8e-05 22.3 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 ETS82414.1 - 0.0002 20.7 1.1 0.019 14.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain TP_methylase PF00590.15 ETS82414.1 - 0.024 14.3 0.2 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases HET PF06985.6 ETS82415.1 - 1.3e-27 96.6 0.0 3.1e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FA_desaturase PF00487.19 ETS82416.1 - 5.4e-11 42.4 29.7 5.4e-11 42.4 20.6 1.7 1 1 1 2 2 2 1 Fatty acid desaturase RNase_H2-Ydr279 PF09468.5 ETS82416.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DHH PF01368.15 ETS82417.1 - 8.3e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 DHH family Abhydrolase_4 PF08386.5 ETS82418.1 - 7.8e-17 61.0 0.0 1.8e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS82418.1 - 1.8e-16 60.4 0.0 1.2e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS82418.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82418.1 - 3e-05 23.8 0.0 0.00032 20.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.14 ETS82421.1 - 1.9e-44 150.9 0.0 1.4e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS82421.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 ETS82421.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NUT_N PF12881.2 ETS82421.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 NUT protein N terminus MFS_1 PF07690.11 ETS82422.1 - 3.3e-31 108.2 27.0 3.3e-31 108.2 18.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82422.1 - 9.5e-13 47.5 14.6 9.5e-13 47.5 10.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 ETS82422.1 - 1.3e-05 23.5 5.2 1.3e-05 23.5 3.6 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 ETS82422.1 - 0.0002 20.2 0.1 0.00035 19.4 0.1 1.4 1 0 0 1 1 1 1 BT1 family DUF3593 PF12159.3 ETS82422.1 - 0.041 13.6 0.2 0.19 11.5 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Pectinesterase PF01095.14 ETS82423.1 - 2.3e-26 92.0 0.1 2.3e-22 78.9 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase Bac_rhodopsin PF01036.13 ETS82424.1 - 5.6e-48 163.1 19.3 7e-48 162.8 13.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Intg_mem_TP0381 PF09529.5 ETS82424.1 - 0.0039 16.4 4.1 0.61 9.2 0.1 2.3 2 0 0 2 2 2 2 Integral membrane protein (intg_mem_TP0381) Gpi1 PF05024.10 ETS82424.1 - 0.018 14.7 3.3 0.024 14.3 2.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) DUF788 PF05620.6 ETS82424.1 - 0.025 14.4 1.4 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) SUR7 PF06687.7 ETS82424.1 - 0.035 13.6 9.9 1.4 8.4 6.5 2.2 1 1 1 2 2 2 0 SUR7/PalI family DUF805 PF05656.9 ETS82424.1 - 0.044 13.6 0.3 0.044 13.6 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF2306 PF10067.4 ETS82424.1 - 2.6 8.2 10.7 0.22 11.6 0.8 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) WD40 PF00400.27 ETS82425.1 - 2e-26 90.8 3.3 2.8e-07 30.1 0.0 8.9 9 0 0 9 9 9 5 WD domain, G-beta repeat NACHT PF05729.7 ETS82425.1 - 1.6e-09 37.6 0.0 4.5e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETS82425.1 - 1.1e-07 31.3 0.1 6 6.6 0.0 6.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 ETS82425.1 - 5.5e-05 23.3 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain PQQ_2 PF13360.1 ETS82425.1 - 0.00037 20.0 0.0 0.0044 16.5 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 ETS82425.1 - 0.0019 17.3 0.2 5.6 5.9 0.0 4.3 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 ETS82425.1 - 0.0024 17.6 0.0 0.0096 15.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain eIF2A PF08662.6 ETS82425.1 - 0.0053 16.4 0.0 0.69 9.5 0.0 3.2 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 ETS82425.1 - 0.032 14.2 0.2 0.19 11.6 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETS82425.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 ETS82425.1 - 0.093 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_9 PF14604.1 ETS82427.1 - 9.9e-09 34.6 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS82427.1 - 0.00059 19.1 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS82427.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PDEase_I_N PF08499.7 ETS82427.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Amnionless PF14828.1 ETS82427.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4293 PF14126.1 ETS82427.1 - 0.28 11.1 0.0 0.59 10.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Macoilin PF09726.4 ETS82427.1 - 0.73 8.0 4.6 0.83 7.8 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 ETS82428.1 - 2.6e-10 39.6 3.2 9.8e-10 37.7 1.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82428.1 - 2.1e-05 24.3 11.4 4.1e-05 23.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 ETS82429.1 - 8.8e-07 29.1 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS82429.1 - 6.1e-05 21.6 0.0 0.17 10.3 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 ETS82430.1 - 2.3e-94 316.5 24.9 2.6e-94 316.3 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82430.1 - 3.4e-29 101.6 47.7 5.7e-24 84.4 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 ETS82430.1 - 0.0048 16.9 19.9 0.46 10.6 2.0 4.8 5 0 0 5 5 5 3 Transglycosylase associated protein DUF3681 PF12442.3 ETS82430.1 - 0.013 15.7 0.1 0.049 13.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DUF1228 PF06779.9 ETS82430.1 - 0.014 15.4 6.2 1.3 9.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Gate PF07670.9 ETS82430.1 - 0.72 9.7 8.2 0.22 11.4 0.9 3.0 2 1 0 2 2 2 0 Nucleoside recognition Pyr_redox_2 PF07992.9 ETS82431.1 - 3.2e-23 82.6 0.0 4.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS82431.1 - 1.1e-07 30.6 0.0 0.00018 20.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 ETS82431.1 - 8.8e-07 28.1 1.0 0.001 18.0 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS82431.1 - 6.8e-05 22.6 0.1 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 ETS82431.1 - 8.9e-05 21.4 0.1 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS82431.1 - 0.00013 21.8 0.1 0.00024 21.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 ETS82431.1 - 0.00024 20.0 0.0 0.0042 15.9 0.0 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS82431.1 - 0.0019 18.3 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS82431.1 - 0.0039 16.3 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 ETS82431.1 - 0.0055 15.6 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 ETS82431.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cytochrom_C PF00034.16 ETS82431.1 - 0.049 14.4 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c Sugar_tr PF00083.19 ETS82432.1 - 2.6e-91 306.4 30.1 3.2e-91 306.1 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82432.1 - 7.6e-10 38.0 50.9 2.6e-08 32.9 10.4 2.8 1 1 1 3 3 3 3 Major Facilitator Superfamily ADH_N PF08240.7 ETS82433.1 - 9.5e-16 57.5 0.1 9.5e-16 57.5 0.1 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82433.1 - 3.1e-08 33.2 0.1 6.5e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribonuc_L-PSP PF01042.16 ETS82434.1 - 1.9e-23 82.5 0.0 2.2e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 ETS82435.1 - 2.4e-10 39.7 0.0 3.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82435.1 - 0.02 14.7 5.0 0.037 13.9 3.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CrtC PF07143.6 ETS82437.1 - 2.6e-13 49.9 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) RTA1 PF04479.8 ETS82438.1 - 1.9e-51 174.7 9.2 1.9e-51 174.7 6.4 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3963 PF13124.1 ETS82438.1 - 0.39 10.5 4.8 6.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) Carboxyl_trans PF01039.17 ETS82440.1 - 0.076 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain SBP_bac_6 PF13343.1 ETS82441.1 - 7.1e-17 61.5 0.7 3.1e-16 59.4 0.5 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 ETS82441.1 - 5.1e-08 33.0 8.3 2.8e-07 30.5 5.8 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 ETS82441.1 - 9.1e-06 25.4 0.2 1.7e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein FAD_binding_4 PF01565.18 ETS82442.1 - 1.4e-21 76.3 0.1 2.7e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS82442.1 - 0.062 13.2 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Zn_clus PF00172.13 ETS82443.1 - 9.5e-08 31.8 9.3 1.4e-07 31.2 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS82443.1 - 0.00051 18.7 0.3 0.00079 18.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 ETS82444.1 - 0.00028 20.0 6.2 0.0052 15.8 4.3 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Striatin PF08232.7 ETS82444.1 - 0.1 12.9 4.3 0.19 12.0 3.0 1.4 1 0 0 1 1 1 0 Striatin family AA_permease_2 PF13520.1 ETS82445.1 - 2e-29 102.4 23.8 3.4e-29 101.6 16.4 1.5 1 1 0 1 1 1 1 Amino acid permease Strep_his_triad PF04270.8 ETS82445.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Streptococcal histidine triad protein Pkinase PF00069.20 ETS82446.1 - 1.7e-15 56.8 0.0 2.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ADH_zinc_N PF00107.21 ETS82447.1 - 3.6e-30 104.1 1.2 5.8e-30 103.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS82447.1 - 3e-24 84.8 0.7 8.4e-24 83.4 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS82447.1 - 1.2e-06 29.4 0.0 1.7e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.10 ETS82447.1 - 0.077 12.5 0.2 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Methyltransf_18 PF12847.2 ETS82447.1 - 0.092 13.3 0.4 0.25 11.9 0.3 1.9 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_S15 PF02129.13 ETS82448.1 - 1.9e-37 129.1 2.6 5.1e-36 124.4 0.5 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS82448.1 - 8.5e-19 68.3 0.0 1.7e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS82448.1 - 2e-07 31.1 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82448.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS82448.1 - 0.096 12.5 0.3 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Nodulin_late PF07127.6 ETS82450.1 - 0.32 11.1 2.5 0.65 10.1 0.6 2.3 2 0 0 2 2 2 0 Late nodulin protein DeoC PF01791.4 ETS82451.1 - 1.5e-41 142.2 0.6 1.7e-41 142.0 0.4 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF1805 PF08827.6 ETS82451.1 - 0.041 13.6 1.7 0.66 9.8 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1805) Abhydrolase_6 PF12697.2 ETS82452.1 - 5.7e-27 95.0 0.0 7e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82452.1 - 9.9e-13 48.1 0.0 1.8e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82452.1 - 1.3e-12 47.6 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 ETS82452.1 - 0.00018 20.7 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 ETS82452.1 - 0.0002 21.6 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 ETS82452.1 - 0.0029 17.0 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF1057 PF06342.7 ETS82452.1 - 0.0029 16.4 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 ETS82452.1 - 0.0064 16.1 0.3 0.02 14.4 0.2 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS82452.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 ETS82452.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase DUF900 PF05990.7 ETS82452.1 - 0.024 13.9 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0227 PF05728.7 ETS82452.1 - 0.042 13.5 0.2 0.091 12.4 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 ETS82452.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MBOAT_2 PF13813.1 ETS82453.1 - 2.8e-23 81.7 0.6 9.3e-23 80.1 0.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CrtC PF07143.6 ETS82455.1 - 2e-16 60.1 1.5 1.1e-15 57.7 1.1 1.9 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) NAD_binding_2 PF03446.10 ETS82457.1 - 2e-30 105.7 0.1 4.4e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS82457.1 - 5.2e-10 39.4 1.0 8.3e-10 38.7 0.7 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 ETS82457.1 - 5e-09 36.3 0.3 1.2e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS82457.1 - 5e-08 33.2 0.2 2.1e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 ETS82457.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.10 ETS82457.1 - 0.0027 16.5 0.0 0.0052 15.6 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.19 ETS82457.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS82457.1 - 0.18 11.5 1.0 0.52 10.0 0.1 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_zinc_N PF00107.21 ETS82458.1 - 2.4e-13 49.7 0.0 5.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS82458.1 - 9.8e-09 34.9 0.2 8.6e-08 31.9 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS82458.1 - 0.0069 17.2 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.6 ETS82459.1 - 2.3e-19 69.9 18.2 3.8e-19 69.2 1.4 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF668 PF05003.7 ETS82459.1 - 0.035 14.3 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) HET PF06985.6 ETS82460.1 - 2.4e-22 79.6 0.2 5.4e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 ETS82461.1 - 1.5e-17 63.4 1.2 3.7e-17 62.1 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Ank_2 PF12796.2 ETS82462.1 - 1.2e-41 140.9 2.5 4.7e-21 74.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82462.1 - 6.1e-32 107.8 0.3 1.4e-09 37.3 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETS82462.1 - 3.4e-23 81.5 0.7 1.1e-10 41.6 0.0 4.0 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS82462.1 - 1.3e-21 76.1 2.7 1.2e-08 34.9 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82462.1 - 1.5e-18 64.9 0.4 0.00013 21.8 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat AAA_16 PF13191.1 ETS82462.1 - 1.2e-07 31.9 0.4 1e-05 25.6 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ETS82462.1 - 2e-07 30.8 0.2 5.6e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS82462.1 - 4.7e-05 23.5 0.0 0.00026 21.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETS82462.1 - 0.027 13.9 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS82462.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF3944 PF13099.1 ETS82462.1 - 0.13 11.7 1.3 0.3 10.6 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) AAA_33 PF13671.1 ETS82462.1 - 0.14 11.9 1.0 0.9 9.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 ETS82463.1 - 4.8e-39 132.5 3.3 2.8e-16 59.6 0.1 4.8 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82463.1 - 1.2e-33 113.2 5.9 1.3e-07 31.0 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 ETS82463.1 - 4.3e-27 93.5 5.7 1.3e-06 28.3 0.1 6.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS82463.1 - 9e-26 89.7 2.0 5e-06 26.8 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82463.1 - 3.7e-21 73.1 2.9 0.0058 16.7 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat RelA_SpoT PF04607.12 ETS82463.1 - 1.7e-10 40.9 0.0 3.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins FA_hydroxylase PF04116.8 ETS82464.1 - 1.8e-15 57.2 17.1 4.7e-15 55.9 10.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_tranf_2_3 PF13641.1 ETS82465.1 - 2.2e-28 99.5 0.0 4.6e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS82465.1 - 2.4e-24 85.9 0.0 6.8e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Polysacc_deac_1 PF01522.16 ETS82465.1 - 1.7e-21 76.1 0.1 4.9e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_trans_2_3 PF13632.1 ETS82465.1 - 2.3e-15 56.8 0.1 6.4e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 ETS82465.1 - 3.4e-09 36.2 0.0 9.4e-09 34.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 ETS82465.1 - 8.5e-06 24.4 0.0 0.0065 14.9 0.0 2.6 2 1 0 3 3 3 2 Chitin synthase FixQ PF05545.6 ETS82465.1 - 0.01 15.4 0.1 0.034 13.7 0.0 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_tranf_2_2 PF10111.4 ETS82465.1 - 0.018 14.1 0.1 0.21 10.6 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 ETS82465.1 - 0.028 14.7 0.1 0.083 13.2 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 MFS_1 PF07690.11 ETS82467.1 - 3.9e-22 78.4 54.9 1.2e-15 57.0 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3433 PF11915.3 ETS82468.1 - 6.6e-15 55.0 10.0 2.5e-10 40.3 0.2 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) HET PF06985.6 ETS82469.1 - 2.7e-21 76.1 3.3 8.6e-17 61.6 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_42 PF02449.10 ETS82472.1 - 1.8e-08 33.9 0.0 4.6e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 ETS82472.1 - 2.5e-07 30.3 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BNR_2 PF13088.1 ETS82473.1 - 0.00082 18.7 0.5 0.023 13.9 0.0 2.6 1 1 1 2 2 2 2 BNR repeat-like domain SAICAR_synt PF01259.13 ETS82473.1 - 0.04 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 SAICAR synthetase BNR PF02012.15 ETS82473.1 - 0.064 13.1 10.4 2 8.5 0.1 4.1 3 0 0 3 3 3 0 BNR/Asp-box repeat DuffyBP_N PF12377.3 ETS82473.1 - 0.078 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Duffy binding protein N terminal DUF3233 PF11557.3 ETS82473.1 - 0.079 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) TGF_beta_GS PF08515.7 ETS82473.1 - 0.89 8.9 3.5 18 4.7 0.1 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Fungal_trans PF04082.13 ETS82474.1 - 7.3e-15 54.5 3.9 1.4e-14 53.6 2.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82474.1 - 1.4e-05 24.8 7.0 3.1e-05 23.8 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 ETS82475.1 - 5.5e-58 196.6 13.0 6.2e-58 196.4 9.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82475.1 - 1.9e-09 36.6 13.3 1.9e-09 36.6 9.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 ETS82476.1 - 1.1e-28 99.4 0.9 1.3e-14 54.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82476.1 - 2.7e-27 93.1 0.1 5.6e-09 35.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS82476.1 - 1.4e-19 70.0 0.5 2.3e-07 31.1 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS82476.1 - 1.3e-18 66.6 0.9 4.8e-08 32.9 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82476.1 - 1.8e-13 49.2 0.1 0.0012 18.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat CorA PF01544.13 ETS82476.1 - 2.3e-12 46.5 0.5 5.2e-12 45.4 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Kelch_4 PF13418.1 ETS82477.1 - 0.71 9.6 3.4 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain HET PF06985.6 ETS82478.1 - 3.6e-32 111.4 0.7 5.9e-32 110.7 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.13 ETS82479.1 - 8.2e-34 117.0 2.3 1.4e-33 116.3 1.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 ETS82479.1 - 7.2e-25 86.6 8.1 5.8e-24 83.7 3.8 3.2 3 0 0 3 3 3 1 Carbohydrate binding domain X2 MMR_HSR1_C PF08438.5 ETS82479.1 - 0.13 12.4 0.0 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 GTPase of unknown function C-terminal Glyco_hydro_43 PF04616.9 ETS82480.1 - 2.8e-28 98.8 0.3 1.3e-27 96.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_6 PF12697.2 ETS82481.1 - 9.2e-28 97.6 0.0 1.1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82481.1 - 2.5e-09 37.0 0.0 7.5e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82481.1 - 5.3e-08 32.7 0.0 7.6e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS82481.1 - 0.0007 19.8 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 ETS82481.1 - 0.0044 16.6 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 ETS82481.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 ETS82481.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 ETS82481.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS82481.1 - 0.17 11.4 0.1 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 3) BCD PF15461.1 ETS82482.1 - 0.079 12.3 0.2 0.096 12.0 0.1 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase SnoaL_2 PF12680.2 ETS82483.1 - 9.1e-08 32.4 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 ETS82483.1 - 0.04 13.8 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain AMP-binding PF00501.23 ETS82484.1 - 1.4e-87 293.8 0.0 2.1e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 ETS82484.1 - 3.2e-78 262.7 0.1 8.7e-78 261.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS82484.1 - 9.6e-58 194.8 1.4 2.8e-57 193.2 1.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS82484.1 - 6.3e-52 176.5 0.6 1.3e-51 175.5 0.4 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS82484.1 - 2.5e-51 173.8 2.9 2.5e-51 173.8 2.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 ETS82484.1 - 5.2e-48 164.0 1.3 1.6e-47 162.4 0.2 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 ETS82484.1 - 6.3e-41 138.9 1.2 2.2e-40 137.2 0.8 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 ETS82484.1 - 5.6e-20 72.5 0.0 1.1e-19 71.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.1 ETS82484.1 - 4.9e-13 49.8 0.2 2.4e-12 47.5 0.0 2.4 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 ETS82484.1 - 9.7e-13 48.1 0.7 4.7e-06 26.7 0.0 3.6 3 0 0 3 3 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS82484.1 - 3e-05 23.1 0.3 0.001 18.1 0.1 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 ETS82484.1 - 3.2e-05 23.6 0.2 0.00043 20.0 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 ETS82484.1 - 0.00027 20.4 0.1 0.00049 19.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 ETS82484.1 - 0.0029 17.2 0.1 0.0098 15.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold NAD_binding_4 PF07993.7 ETS82484.1 - 0.011 14.6 0.1 0.029 13.3 0.1 1.7 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 ETS82484.1 - 0.017 13.8 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS82484.1 - 0.025 13.4 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.15 ETS82484.1 - 0.049 13.1 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS82484.1 - 0.056 13.0 0.0 8.7 5.9 0.0 3.1 2 0 0 2 2 2 0 Lipase (class 3) NmrA PF05368.8 ETS82484.1 - 0.15 11.2 0.3 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family Glyco_hydro_42 PF02449.10 ETS82485.1 - 2.8e-11 43.1 0.0 4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 ETS82485.1 - 2.7e-09 36.8 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 ETS82485.1 - 0.032 13.2 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Chitin_synth_2 PF03142.10 ETS82486.1 - 6.2e-253 839.9 1.2 8.7e-253 839.4 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 ETS82486.1 - 7.1e-169 563.0 0.0 9.4e-169 562.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 ETS82486.1 - 1.7e-18 66.1 0.4 1.3e-17 63.2 0.3 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 ETS82486.1 - 3.3e-18 65.2 0.0 1.6e-13 50.2 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 ETS82486.1 - 8.1e-15 55.0 5.9 8.1e-15 55.0 4.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS82486.1 - 1.9e-14 54.0 0.2 7.6e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS82486.1 - 0.00019 21.1 0.0 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_22 PF13401.1 ETS82486.1 - 0.0049 16.9 0.3 0.029 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS82486.1 - 0.0077 16.2 0.1 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 ETS82486.1 - 0.033 13.7 0.2 0.21 11.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_21 PF13506.1 ETS82486.1 - 0.038 13.2 0.3 0.099 11.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 ABC_tran PF00005.22 ETS82486.1 - 0.066 13.5 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 ETS82486.1 - 0.083 12.0 0.1 0.4 9.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS82486.1 - 0.098 12.0 0.0 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS82486.1 - 0.11 12.7 0.1 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 ETS82486.1 - 0.13 11.4 0.6 0.57 9.3 0.4 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.4 ETS82486.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SFTA2 PF15210.1 ETS82486.1 - 0.2 11.2 2.4 0.15 11.6 0.1 2.0 2 0 0 2 2 1 0 Surfactant-associated protein 2 Chitin_synth_2 PF03142.10 ETS82487.1 - 1.9e-231 769.0 0.1 2.7e-231 768.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 ETS82487.1 - 1.4e-58 198.5 0.0 4.5e-58 196.8 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 ETS82487.1 - 1.1e-16 60.3 0.0 6.2e-11 41.9 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 ETS82487.1 - 1e-15 57.9 2.9 1e-15 57.9 2.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 ETS82487.1 - 1e-14 54.0 2.2 1.8e-13 50.0 1.8 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 ETS82487.1 - 1.1e-13 51.4 0.0 1.1e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 ETS82487.1 - 1e-06 28.1 0.0 3.9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 ETS82487.1 - 0.00078 19.1 0.0 0.041 13.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.4 ETS82488.1 - 1.2e-43 148.5 0.0 1.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 ETS82488.1 - 7.6e-17 61.0 0.0 3e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 ETS82488.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.11 ETS82489.1 - 4.3e-15 56.0 0.4 4.8e-15 55.8 0.3 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF663 PF04950.7 ETS82490.1 - 1e-91 306.9 0.0 1e-91 306.9 0.0 2.3 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 ETS82490.1 - 1.6e-27 94.8 0.0 6.2e-27 92.9 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 ETS82490.1 - 3.9e-06 26.4 0.0 0.00075 18.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 ETS82490.1 - 9.3e-06 25.7 0.1 3.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS82490.1 - 1.8e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 ETS82490.1 - 0.00012 21.7 0.0 0.00036 20.2 0.0 1.9 2 0 0 2 2 1 1 NACHT domain AAA PF00004.24 ETS82490.1 - 0.00027 21.1 0.0 0.00064 19.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETS82490.1 - 0.00028 21.2 0.3 0.003 17.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 ETS82490.1 - 0.00031 20.6 0.3 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS82490.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 ETS82490.1 - 0.00056 19.6 0.1 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 ETS82490.1 - 0.00092 19.7 0.0 0.0029 18.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 ETS82490.1 - 0.0011 18.4 0.0 0.0034 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETS82490.1 - 0.0013 17.9 0.0 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS82490.1 - 0.0021 18.8 0.0 0.0021 18.8 0.0 4.3 3 1 1 4 4 2 1 AAA domain AAA_14 PF13173.1 ETS82490.1 - 0.003 17.4 0.0 0.0089 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 ETS82490.1 - 0.0032 17.1 1.2 0.011 15.4 0.0 2.4 3 1 0 4 4 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 ETS82490.1 - 0.0038 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 ETS82490.1 - 0.0045 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase PduV-EutP PF10662.4 ETS82490.1 - 0.0049 16.3 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 ETS82490.1 - 0.006 16.8 0.0 0.006 16.8 0.0 4.0 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.10 ETS82490.1 - 0.01 15.5 0.2 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 ETS82490.1 - 0.011 14.5 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 ETS82490.1 - 0.012 15.2 0.1 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 ETS82490.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 ETS82490.1 - 0.041 13.6 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 ETS82490.1 - 1.3 8.5 6.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Na_Ca_ex PF01699.19 ETS82492.1 - 6.6e-22 77.6 24.0 6.7e-13 48.4 3.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2976 PF11190.3 ETS82492.1 - 0.51 9.9 0.0 0.51 9.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Mac PF12464.3 ETS82493.1 - 1.6e-19 69.6 0.0 2.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 ETS82493.1 - 7.4e-15 53.7 11.8 5.2e-13 47.8 3.7 3.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS82493.1 - 2.1e-14 52.7 11.7 5.7e-14 51.3 2.8 3.2 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 ETS82493.1 - 0.048 13.6 1.7 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Bacteriocin subtilosin A Polysacc_deac_1 PF01522.16 ETS82494.1 - 7.5e-27 93.4 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase zf-RING_2 PF13639.1 ETS82495.1 - 2.5e-09 36.8 7.3 5.3e-09 35.7 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS82495.1 - 3.2e-07 30.3 1.4 9.6e-07 28.8 1.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 ETS82495.1 - 5.2e-06 26.3 7.8 1.6e-05 24.7 5.4 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 ETS82495.1 - 6.4e-05 22.7 2.2 0.00019 21.1 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 ETS82495.1 - 0.00037 20.4 7.6 0.00095 19.1 5.2 1.8 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 ETS82495.1 - 0.0025 17.5 2.3 0.0025 17.5 1.6 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 ETS82495.1 - 0.0027 17.3 9.0 0.0063 16.1 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS82495.1 - 0.0033 17.4 8.6 0.0085 16.0 6.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS82495.1 - 0.0036 16.9 4.7 0.0081 15.8 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 ETS82495.1 - 0.051 13.4 1.1 0.12 12.1 0.8 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 ETS82495.1 - 0.09 12.7 8.7 0.24 11.4 4.9 2.2 2 0 0 2 2 2 0 RING-like domain zf-RING_5 PF14634.1 ETS82495.1 - 0.19 11.4 8.3 0.46 10.2 5.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 ETS82495.1 - 1.9 8.2 6.7 4.9 6.9 4.6 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 ETS82495.1 - 2.5 7.7 6.2 47 3.6 4.3 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 ETS82495.1 - 5.5 6.8 4.9 21 4.9 3.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 MgtE_N PF03448.12 ETS82496.1 - 0.48 10.7 8.7 6.8 7.0 0.3 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain HET PF06985.6 ETS82497.1 - 2.5e-26 92.4 0.5 4.1e-26 91.7 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RhoGAP PF00620.22 ETS82500.1 - 4.6e-20 71.7 0.0 9.5e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain HeLo PF14479.1 ETS82501.1 - 2.9e-07 30.4 1.1 1e-06 28.6 0.8 1.9 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 ETS82501.1 - 0.003 16.7 0.0 0.008 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 ETS82502.1 - 1.4e-36 125.9 0.0 2.1e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82502.1 - 3.1e-25 88.7 0.0 4.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS82502.1 - 0.0026 17.5 2.6 0.0076 16.0 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Adeno_terminal PF02459.10 ETS82502.1 - 0.02 13.1 0.1 0.031 12.4 0.1 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Glyco_hydro_1 PF00232.13 ETS82503.1 - 7.5e-71 238.6 0.3 3.6e-70 236.4 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Palm_thioest PF02089.10 ETS82504.1 - 4.2e-53 180.0 0.0 5.6e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 ETS82504.1 - 0.00011 21.6 0.0 0.0018 17.5 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.6 ETS82504.1 - 0.00014 21.0 0.0 0.00028 20.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 ETS82504.1 - 0.016 14.9 0.2 0.038 13.7 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L1 PF00687.16 ETS82505.1 - 3.3e-55 186.8 2.4 3.3e-55 186.8 1.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Cyclin_N PF00134.18 ETS82506.1 - 1.1e-05 25.0 0.1 1.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_30 PF02055.11 ETS82507.1 - 1.4e-20 73.0 1.5 3.1e-14 52.0 0.8 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 ETS82507.1 - 4.6e-14 52.1 0.0 1.4e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Abhydrolase_3 PF07859.8 ETS82508.1 - 2.7e-08 33.6 0.3 1.1e-06 28.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82508.1 - 1.4e-07 31.3 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82508.1 - 1.1e-05 25.3 3.8 0.00016 21.6 2.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS82508.1 - 2e-05 23.9 0.0 0.00025 20.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 ETS82508.1 - 6.8e-05 22.2 0.0 0.0015 17.8 0.0 2.6 2 1 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 ETS82508.1 - 0.0037 16.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold YjeF_N PF03853.10 ETS82508.1 - 0.043 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus FSH1 PF03959.8 ETS82508.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 ETS82508.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase GST_N_2 PF13409.1 ETS82510.1 - 1.1e-20 73.4 0.1 2.9e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS82510.1 - 1.7e-13 50.2 0.0 3.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS82510.1 - 3.1e-08 33.4 0.0 6.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS82510.1 - 8.1e-06 25.9 0.0 0.056 13.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS82510.1 - 0.00045 20.6 0.0 0.00078 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.16 ETS82511.1 - 2.9e-51 172.8 0.2 1.2e-31 109.3 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 ETS82511.1 - 5.2e-40 136.4 0.1 1.3e-39 135.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 ETS82511.1 - 6.2e-39 131.4 4.7 2.6e-27 94.1 0.3 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETS82511.1 - 1.7e-24 84.8 1.1 1.8e-21 75.2 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Kelch_5 PF13854.1 ETS82513.1 - 5.7e-12 45.3 4.5 4.1e-10 39.3 0.5 4.1 3 0 0 3 3 3 1 Kelch motif Shisa PF13908.1 ETS82513.1 - 0.93 9.6 3.0 8.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SKG6 PF08693.5 ETS82513.1 - 1.1 8.5 8.8 0.54 9.6 3.8 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain His_Phos_1 PF00300.17 ETS82515.1 - 1.7e-30 106.2 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2797 PF10977.3 ETS82516.1 - 0.044 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF963 PF06131.6 ETS82517.1 - 0.012 14.8 5.5 0.012 14.8 3.8 2.1 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) p450 PF00067.17 ETS82518.1 - 3.3e-19 68.7 0.0 3.3e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.15 ETS82519.1 - 1.1e-21 76.3 6.5 3.6e-07 29.9 0.0 5.5 5 0 0 5 5 5 5 LysM domain Chitin_bind_1 PF00187.14 ETS82519.1 - 8.2e-09 35.3 53.9 0.00024 21.0 14.8 3.9 2 1 0 2 2 2 2 Chitin recognition protein Glyco_hydro_18 PF00704.23 ETS82520.1 - 3.7e-80 269.9 6.1 4e-80 269.8 2.6 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS82520.1 - 4.9e-13 48.8 45.7 1.8e-11 43.7 10.9 5.1 7 0 0 7 7 7 2 Chitin recognition protein HET PF06985.6 ETS82522.1 - 1.4e-25 90.0 0.0 4e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Eaf7 PF07904.8 ETS82523.1 - 2.9e-27 94.4 0.0 2.9e-27 94.4 0.0 2.2 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Daxx PF03344.10 ETS82523.1 - 0.077 11.4 27.1 0.12 10.8 18.8 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETS82523.1 - 0.12 10.2 30.6 0.15 9.9 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 ETS82523.1 - 2.5 7.5 25.5 0.48 9.9 15.1 1.7 2 0 0 2 2 2 0 PPP4R2 CobT PF06213.7 ETS82523.1 - 4.8 6.2 26.1 9.3 5.2 18.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 ETS82523.1 - 6 4.7 23.3 8.1 4.3 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 ETS82523.1 - 8.5 5.5 14.6 14 4.8 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein Spc97_Spc98 PF04130.8 ETS82524.1 - 6.4e-79 265.7 0.0 8.5e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DASH_Ask1 PF08655.5 ETS82525.1 - 7.3e-33 112.2 0.1 1.4e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 YqfQ PF14181.1 ETS82525.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 YqfQ-like protein p450 PF00067.17 ETS82527.1 - 1e-51 175.9 0.0 1.4e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 ETS82528.1 - 4.2e-83 279.8 0.1 7.3e-83 279.0 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Thymopoietin PF08198.6 ETS82528.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymopoietin protein Acetyltransf_7 PF13508.1 ETS82529.1 - 0.0046 17.1 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS82529.1 - 0.0049 16.7 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS82529.1 - 0.014 15.5 0.1 0.044 13.9 0.0 2.0 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS82529.1 - 0.12 12.3 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Rhodanese PF00581.15 ETS82530.1 - 1e-13 51.6 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.12 ETS82531.1 - 1e-11 44.6 16.4 2e-11 43.7 11.4 1.5 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 ETS82532.1 - 1.4e-34 117.3 0.9 1.8e-34 116.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 ETS82532.1 - 3.2e-30 103.4 10.2 5e-30 102.8 7.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 ETS82532.1 - 1e-19 69.9 0.6 1.5e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS82532.1 - 5.1e-06 26.6 0.2 1.8e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 ETS82532.1 - 0.00018 21.2 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 ETS82532.1 - 0.0069 16.2 0.1 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETS82532.1 - 0.0087 16.2 0.1 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 ETS82532.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 ETS82532.1 - 0.16 10.2 0.4 3 6.0 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain RRN7 PF11781.3 ETS82534.1 - 8.9e-05 21.9 2.4 0.00015 21.2 1.7 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5a PF01287.15 ETS82535.1 - 1.2e-21 76.3 3.2 1.2e-19 70.0 0.7 2.2 2 0 0 2 2 2 2 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 ETS82535.1 - 0.0016 18.0 0.4 0.0033 17.0 0.3 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 ETS82535.1 - 0.0025 17.6 0.3 0.004 16.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 ETS82536.1 - 3.9e-120 401.7 0.0 5.1e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 ETS82536.1 - 1.2e-06 27.0 2.2 2.7e-05 22.5 1.7 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 ETS82536.1 - 0.0061 16.5 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Mer2 DUF1664 PF07889.7 ETS82536.1 - 0.013 15.3 0.2 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ada3 PF10198.4 ETS82536.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 CENP-F_leu_zip PF10473.4 ETS82536.1 - 0.33 10.7 1.9 0.44 10.3 0.4 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RabGAP-TBC PF00566.13 ETS82537.1 - 7.9e-23 81.0 0.0 1.6e-22 80.0 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 ETS82538.1 - 3.9e-76 256.2 0.0 1.4e-75 254.4 0.0 1.9 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 ETS82538.1 - 0.00085 18.4 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region IKI3 PF04762.7 ETS82538.1 - 0.0023 15.8 0.0 0.084 10.6 0.0 2.1 2 0 0 2 2 2 2 IKI3 family GTP_EFTU PF00009.22 ETS82539.1 - 4.9e-33 114.1 0.1 2.8e-32 111.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETS82539.1 - 1.7e-18 66.4 0.0 4.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 ETS82539.1 - 3.4e-10 39.8 3.5 7.9e-08 32.3 0.2 3.4 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS82539.1 - 2e-06 27.7 0.1 8.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 ETS82539.1 - 0.00021 20.9 0.1 0.00073 19.1 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 ETS82539.1 - 0.0022 18.4 1.2 0.0066 16.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 ETS82539.1 - 0.005 16.4 1.8 0.0065 16.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 TrkA_C PF02080.16 ETS82539.1 - 0.039 13.5 1.5 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 TrkA-C domain AAA_16 PF13191.1 ETS82539.1 - 0.051 13.5 0.0 0.051 13.5 0.0 3.0 1 1 1 2 2 2 0 AAA ATPase domain Ank_2 PF12796.2 ETS82540.1 - 2.1e-263 851.6 72.8 2.4e-20 72.6 0.3 15.9 2 2 14 18 18 18 18 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82540.1 - 2.1e-201 642.5 63.1 3.6e-08 32.8 0.0 33.8 34 0 0 34 34 34 33 Ankyrin repeat Ank_4 PF13637.1 ETS82540.1 - 5.8e-136 440.7 39.9 5.4e-10 39.5 0.1 23.1 5 2 23 28 28 28 28 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82540.1 - 1.4e-135 427.3 28.8 4.3e-05 23.3 0.0 33.2 34 0 0 34 34 34 28 Ankyrin repeat Ank_5 PF13857.1 ETS82540.1 - 2.2e-126 409.0 56.6 2.8e-09 36.9 0.1 24.3 7 4 20 27 27 27 27 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 ETS82540.1 - 0.52 9.7 0.7 94 2.3 0.0 4.5 3 1 1 5 5 5 0 Shigella flexneri OspC protein WD40 PF00400.27 ETS82541.1 - 7.2e-93 301.4 65.8 1.9e-13 49.6 0.8 13.9 13 0 0 13 13 13 12 WD domain, G-beta repeat Nup160 PF11715.3 ETS82541.1 - 2.2e-13 49.2 32.1 0.015 13.4 0.1 8.5 3 2 5 9 9 9 6 Nucleoporin Nup120/160 AAA_16 PF13191.1 ETS82541.1 - 2.7e-08 34.0 0.0 6.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETS82541.1 - 1.3e-07 31.4 0.1 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 ETS82541.1 - 0.00033 20.8 0.0 0.00069 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 ETS82541.1 - 0.00063 18.8 2.7 0.0011 18.0 0.7 1.9 1 1 1 2 2 2 1 KAP family P-loop domain APS_kinase PF01583.15 ETS82541.1 - 0.0035 17.0 0.1 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.17 ETS82541.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 ETS82541.1 - 0.016 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS82541.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nucleoporin_N PF08801.6 ETS82541.1 - 0.072 11.8 20.6 2.3 6.8 1.9 5.7 2 1 2 5 5 5 0 Nup133 N terminal like AAA_33 PF13671.1 ETS82541.1 - 0.13 12.1 0.1 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS82541.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Coatomer_WDAD PF04053.9 ETS82541.1 - 0.27 9.9 8.7 0.53 9.0 1.5 3.3 1 1 2 3 3 3 0 Coatomer WD associated region SusE PF14292.1 ETS82541.1 - 0.42 10.4 4.6 6.2 6.6 0.2 2.5 2 0 0 2 2 2 0 SusE outer membrane protein IKI3 PF04762.7 ETS82541.1 - 2 6.1 19.1 1 7.0 1.9 3.9 1 1 1 3 3 3 0 IKI3 family PNP_UDP_1 PF01048.15 ETS82542.1 - 2.2e-14 52.9 1.7 2.2e-13 49.7 1.2 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily CoA_binding_2 PF13380.1 ETS82543.1 - 7.9e-27 93.7 0.0 9.9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 ETS82543.1 - 0.15 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Methyltransf_11 PF08241.7 ETS82544.1 - 3.5e-17 62.6 0.0 5.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82544.1 - 4.2e-12 46.6 0.0 8.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82544.1 - 9e-09 35.0 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS82544.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS82544.1 - 1.9e-08 34.2 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS82544.1 - 6.7e-08 32.8 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS82544.1 - 2.7e-06 26.6 0.0 3.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS82544.1 - 0.0002 20.8 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS82544.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 ETS82544.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 ETS82544.1 - 0.0014 17.6 0.0 0.0032 16.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 ETS82544.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW EF-hand_7 PF13499.1 ETS82545.1 - 3.4e-16 59.1 0.4 2.4e-10 40.3 0.3 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 ETS82545.1 - 1.8e-13 49.1 0.5 3.1e-05 23.4 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 ETS82545.1 - 6.4e-12 43.8 0.5 0.00043 19.4 0.0 4.2 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 ETS82545.1 - 5.2e-11 42.2 0.0 3.9e-05 23.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 ETS82545.1 - 9.1e-09 34.7 1.2 0.00041 19.9 0.1 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETS82545.1 - 0.0081 15.4 1.3 2.2 7.7 0.7 3.2 3 0 0 3 3 3 1 EF hand Peptidase_M3 PF01432.15 ETS82546.1 - 3.9e-154 514.0 0.0 5e-154 513.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 ETS82546.1 - 0.017 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Effector protein p450 PF00067.17 ETS82547.1 - 4.5e-35 121.0 0.0 5.5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 ETS82548.1 - 1.2e-39 136.0 54.8 1.5e-39 135.7 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS82548.1 - 2.6e-16 59.0 43.4 7.5e-16 57.5 30.1 1.5 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 ETS82549.1 - 1.1e-24 87.6 0.1 5e-24 85.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82549.1 - 2.8e-08 33.5 2.2 9.9e-08 31.8 1.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82549.1 - 3.6e-08 33.2 0.0 1.4e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS82549.1 - 8.7e-08 31.9 0.0 2.8e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Esterase PF00756.15 ETS82549.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.3 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.7 ETS82549.1 - 0.028 12.8 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_cc PF11790.3 ETS82550.1 - 2.5e-63 213.7 1.0 3.5e-63 213.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 ETS82551.1 - 1.7e-07 31.0 15.8 3.7e-07 29.9 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS82551.1 - 3.5e-05 22.5 2.2 7.9e-05 21.4 1.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3433 PF11915.3 ETS82552.1 - 5.1e-31 106.6 11.1 1.7e-20 72.9 1.3 3.7 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Peroxidase_2 PF01328.12 ETS82553.1 - 2.2e-35 121.8 0.1 2.9e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 ETS82554.1 - 2e-30 105.7 22.1 2.7e-30 105.2 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FIST PF08495.5 ETS82554.1 - 0.028 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 FIST N domain Neurensin PF14927.1 ETS82554.1 - 0.088 12.1 0.3 9.8 5.5 0.1 2.8 2 0 0 2 2 2 0 Neurensin SATase_N PF06426.9 ETS82555.1 - 8.1 6.7 10.0 0.56 10.4 0.8 3.2 2 1 1 3 3 3 0 Serine acetyltransferase, N-terminal Spherulin4 PF12138.3 ETS82556.1 - 7.2e-74 248.4 3.8 1.8e-57 194.6 1.1 2.0 2 0 0 2 2 2 2 Spherulation-specific family 4 PocR PF10114.4 ETS82556.1 - 0.051 12.7 0.2 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Sensory domain found in PocR Bul1_N PF04425.7 ETS82558.1 - 3.3e-06 25.9 0.0 0.00014 20.5 0.0 2.2 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 ETS82558.1 - 1.2e-05 24.6 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Zip PF02535.17 ETS82559.1 - 5.9e-57 193.0 9.5 1.8e-56 191.4 6.6 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter REGB_T4 PF10715.4 ETS82559.1 - 0.22 11.6 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease RegB T4-bacteriophage encoded OPT PF03169.10 ETS82560.1 - 7.9e-208 691.8 31.9 9.3e-208 691.6 22.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.15 ETS82561.1 - 1.3e-27 96.8 0.0 2e-27 96.1 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 ETS82562.1 - 6.1e-16 57.7 0.2 7.5e-16 57.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 ETS82563.1 - 3.5e-27 95.1 4.4 1e-26 93.6 0.2 3.8 5 1 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 ETS82563.1 - 4.9e-08 32.7 0.1 2e-07 30.8 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 ETS82563.1 - 0.0042 17.3 4.4 3.5 7.9 0.0 4.9 5 0 0 5 5 5 2 HEAT repeats Adaptin_N PF01602.15 ETS82563.1 - 0.0083 14.4 1.2 0.39 8.9 0.2 2.7 2 0 0 2 2 2 2 Adaptin N terminal region GTP_EFTU PF00009.22 ETS82564.1 - 1.9e-62 210.0 0.1 2.7e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 ETS82564.1 - 2e-36 124.1 0.0 4.9e-36 122.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 ETS82564.1 - 7.3e-22 77.0 0.0 1.8e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS82564.1 - 2.5e-12 46.7 2.2 3e-12 46.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETS82564.1 - 8e-11 41.6 0.0 2.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 ETS82564.1 - 2.3e-05 24.3 0.1 5.3e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NUDIX PF00293.23 ETS82565.1 - 3e-07 30.1 0.0 5.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.19 ETS82566.1 - 8.3e-07 28.9 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS82566.1 - 3.7e-06 27.0 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS82566.1 - 3.2e-05 23.6 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS82566.1 - 9.4e-05 22.5 0.1 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS82566.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4401 PF14351.1 ETS82567.1 - 0.39 9.6 2.4 0.72 8.7 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Solute_trans_a PF03619.11 ETS82568.1 - 7.3e-105 350.2 8.9 8.7e-105 349.9 6.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.11 ETS82569.1 - 1.1e-24 86.8 28.3 1.1e-24 86.8 19.6 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82569.1 - 1.1e-08 34.0 15.7 1.1e-08 34.0 10.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.20 ETS82570.1 - 4.8e-73 245.4 0.0 6.1e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS82570.1 - 1.3e-31 109.5 0.0 1.8e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS82570.1 - 7.6e-06 25.1 0.0 2.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS82570.1 - 0.00025 20.8 0.1 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS82570.1 - 0.00043 19.3 0.0 0.022 13.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 ETS82570.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AA_permease PF00324.16 ETS82571.1 - 1.8e-103 346.4 34.3 2.2e-103 346.1 23.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS82571.1 - 7.4e-27 93.9 35.8 3.7e-26 91.6 24.2 2.1 1 1 0 1 1 1 1 Amino acid permease Usher PF00577.15 ETS82571.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Outer membrane usher protein Avl9 PF09794.4 ETS82572.1 - 3.9e-144 479.7 0.0 5e-144 479.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 ETS82572.1 - 5.1e-08 32.5 2.8 2e-06 27.3 0.1 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 ETS82572.1 - 2.5e-06 27.1 0.1 0.00047 19.8 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis AIF-MLS PF14962.1 ETS82572.1 - 6.8 6.2 15.7 11 5.5 0.7 2.3 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Peptidase_S64 PF08192.6 ETS82572.1 - 9.5 4.4 7.4 4.6 5.4 3.7 1.4 1 1 0 1 1 1 0 Peptidase family S64 F-box-like PF12937.2 ETS82573.1 - 3e-07 30.0 0.4 3e-07 30.0 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS82573.1 - 1.1e-05 24.9 0.2 1.1e-05 24.9 0.2 2.0 2 0 0 2 2 2 1 F-box domain Fungal_trans PF04082.13 ETS82574.1 - 8.4e-61 205.1 0.0 1.3e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS82574.1 - 3.1e-07 30.3 10.3 0.00018 21.6 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS82574.1 - 3.2e-06 27.0 10.3 0.003 17.7 0.9 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger FAD_binding_3 PF01494.14 ETS82575.1 - 1.4e-21 76.9 0.4 3.4e-21 75.6 0.0 1.7 2 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 ETS82575.1 - 1.8e-05 23.9 0.1 0.0032 16.6 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 ETS82575.1 - 0.00085 18.3 3.9 0.19 10.6 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 ETS82575.1 - 0.098 11.5 2.2 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase SE PF08491.5 ETS82575.1 - 0.12 11.1 0.0 6.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Fungal_trans PF04082.13 ETS82576.1 - 8.8e-14 50.9 0.3 2.1e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82576.1 - 1.2e-08 34.6 12.8 2.4e-08 33.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP30_Sin3_bdg PF13867.1 ETS82577.1 - 2e-09 37.1 1.7 2.5e-09 36.8 0.2 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CTDII PF01556.13 ETS82578.1 - 5.7e-28 96.6 1.7 1.6e-21 76.0 0.1 3.6 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 ETS82578.1 - 5.7e-24 83.6 0.9 5.7e-24 83.6 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 ETS82578.1 - 5e-10 39.2 21.9 9.9e-10 38.3 15.2 1.5 1 0 0 1 1 1 1 DnaJ central domain SerH PF06873.6 ETS82578.1 - 0.46 9.0 10.3 0.095 11.2 4.9 1.4 2 0 0 2 2 2 0 Cell surface immobilisation antigen SerH BRO1 PF03097.13 ETS82579.1 - 2.1e-128 428.2 4.1 2.1e-128 428.2 2.9 2.6 3 1 1 4 4 4 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 ETS82579.1 - 2.4e-94 315.6 18.5 2.4e-94 315.6 12.8 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV FlaC_arch PF05377.6 ETS82579.1 - 0.28 11.0 3.1 0.71 9.8 0.0 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.1 ETS82579.1 - 1.6 7.5 17.2 0.6 9.0 7.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lactamase_B_2 PF12706.2 ETS82580.1 - 5.4e-35 120.6 0.0 7.5e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS82580.1 - 3.8e-09 36.4 0.0 6.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS82580.1 - 0.00081 19.0 1.0 0.0095 15.5 0.2 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily fn3_3 PF14686.1 ETS82581.1 - 2.3e-10 40.4 0.3 2.3e-10 40.4 0.2 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 ETS82581.1 - 1e-09 38.2 0.1 2.4e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 ETS82581.1 - 0.00079 19.4 0.2 0.0059 16.6 0.1 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DAO PF01266.19 ETS82582.1 - 1.8e-47 162.0 3.9 2e-47 161.8 2.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS82582.1 - 0.00027 20.9 0.5 0.00066 19.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS82582.1 - 0.00035 20.6 0.0 0.054 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 ETS82582.1 - 0.031 12.4 0.0 0.56 8.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 ETS82582.1 - 0.045 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2415 PF10313.4 ETS82583.1 - 2.2e-13 49.6 0.0 5.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 ETS82583.1 - 4.3e-06 26.4 0.7 0.022 14.6 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat HSP70 PF00012.15 ETS82584.1 - 7e-265 879.6 15.8 8e-265 879.4 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS82584.1 - 2.7e-14 52.5 3.7 4e-12 45.3 0.6 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 ETS82584.1 - 0.00035 20.2 0.1 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 ETS82584.1 - 0.0058 16.4 8.6 0.73 9.6 0.1 4.2 3 2 0 3 3 3 2 Cell division protein FtsA DUF4363 PF14276.1 ETS82584.1 - 0.091 12.4 2.5 0.19 11.4 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DnaG_DnaB_bind PF08278.6 ETS82584.1 - 2.2 8.4 6.0 2.5 8.3 2.1 2.5 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Cu-oxidase_3 PF07732.10 ETS82585.1 - 3.3e-43 146.1 4.8 7.9e-43 144.9 0.6 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS82585.1 - 1e-39 135.2 7.3 1.6e-34 118.3 2.0 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 ETS82585.1 - 1.1e-28 100.0 0.0 1.5e-27 96.4 0.0 2.7 3 1 0 3 3 3 1 Multicopper oxidase Frataxin_Cyay PF01491.11 ETS82585.1 - 0.12 12.1 0.1 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Frataxin-like domain PPR PF01535.15 ETS82587.1 - 2.1e-15 55.5 1.6 0.0013 18.6 0.0 7.0 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.1 ETS82587.1 - 3e-13 49.5 1.4 0.029 14.3 0.0 6.3 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.1 ETS82587.1 - 2.9e-11 42.7 5.6 0.03 14.5 0.0 8.6 10 0 0 10 10 10 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 ETS82587.1 - 0.00055 19.3 0.3 0.15 11.5 0.0 2.8 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.1 ETS82587.1 - 0.00067 20.0 5.5 3.9 8.3 0.0 6.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS82587.1 - 0.0014 18.2 0.4 0.42 10.5 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS82587.1 - 0.042 13.7 0.1 2.4 8.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS82587.1 - 0.066 13.6 0.5 3.3 8.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS82587.1 - 0.074 12.8 0.3 2.7 7.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS82587.1 - 2.2 8.4 6.8 0.4 10.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2046 PF09755.4 ETS82588.1 - 0.0021 16.9 4.4 0.013 14.3 0.8 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TSC22 PF01166.13 ETS82588.1 - 0.022 14.7 1.3 0.022 14.7 0.9 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family End3 PF12761.2 ETS82588.1 - 0.26 10.9 4.0 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pox_A_type_inc PF04508.7 ETS82588.1 - 0.46 10.3 3.4 0.23 11.3 0.3 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DivIVA PF05103.8 ETS82588.1 - 0.81 9.7 5.5 0.26 11.3 0.2 2.1 2 0 0 2 2 2 0 DivIVA protein TMCO5 PF14992.1 ETS82588.1 - 0.92 8.5 5.7 0.1 11.7 0.4 1.7 2 0 0 2 2 2 0 TMCO5 family Spc24 PF08286.6 ETS82588.1 - 1.6 8.4 6.1 2.1 8.0 0.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 ETS82588.1 - 2.8 8.3 5.6 1.4 9.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MerR-DNA-bind PF09278.6 ETS82588.1 - 3.2 8.2 9.3 1.4 9.3 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding MRP-S22 PF10245.4 ETS82589.1 - 0.051 12.9 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 eIF3g PF12353.3 ETS82590.1 - 1.9e-47 160.3 5.6 2.8e-47 159.8 3.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 ETS82590.1 - 1.6e-15 56.4 0.1 1.6e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS82590.1 - 1.7e-12 47.1 1.3 2.2e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS82590.1 - 4.3e-09 36.0 1.1 2.6e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_oxidored PF12831.2 ETS82591.1 - 0.035 13.1 0.3 0.036 13.1 0.2 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase PEMT PF04191.8 ETS82592.1 - 3.4e-58 194.3 9.0 3.4e-36 123.5 0.8 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase Aldolase_II PF00596.16 ETS82593.1 - 3.9e-44 150.4 0.0 4.9e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 ETS82593.1 - 0.013 15.0 0.1 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Nol1_Nop2_Fmu PF01189.12 ETS82594.1 - 1.2e-33 116.7 0.0 8.3e-18 64.7 0.0 5.3 3 2 2 5 5 5 5 NOL1/NOP2/sun family FtsJ PF01728.14 ETS82594.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 ETS82594.1 - 0.029 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GTP1_OBG PF01018.17 ETS82595.1 - 1e-37 129.2 2.5 2.8e-27 95.2 2.2 2.9 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 ETS82595.1 - 6.6e-22 77.6 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS82595.1 - 2.8e-08 33.2 0.0 7.5e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 ETS82595.1 - 0.022 15.5 0.7 0.97 10.2 0.1 3.0 3 1 0 3 3 3 0 AAA domain ArgK PF03308.11 ETS82595.1 - 0.032 13.0 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 ETS82595.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 ETS82595.1 - 0.065 12.4 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 ETS82595.1 - 0.081 12.7 0.0 0.77 9.5 0.0 2.2 1 1 0 1 1 1 0 Dynamin family Prok-JAB PF14464.1 ETS82595.1 - 0.098 12.2 1.6 0.27 10.8 1.1 1.7 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Baculo_PEP_C PF04513.7 ETS82597.1 - 2.2 8.0 11.9 4.8 7.0 1.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 ETS82597.1 - 9.8 5.1 59.0 0.2 10.6 14.4 3.7 2 1 2 4 4 4 0 Autophagy protein Apg6 RNA_pol_Rpb5_C PF01191.14 ETS82598.1 - 3.8e-33 112.8 0.5 6.6e-33 112.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 ETS82598.1 - 8.4e-27 93.4 0.2 1.4e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain p450 PF00067.17 ETS82599.1 - 9.2e-19 67.2 0.0 1.5e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 TFCD_C PF12612.3 ETS82601.1 - 5.3e-24 84.7 3.6 7.5e-24 84.2 0.2 3.0 3 1 1 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 ETS82601.1 - 0.046 13.8 7.2 0.45 10.7 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat Vac14_Fab1_bd PF12755.2 ETS82601.1 - 0.047 14.0 0.0 0.31 11.4 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF1376 PF07120.6 ETS82601.1 - 0.11 12.6 0.1 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) Glyco_hydro_76 PF03663.9 ETS82602.1 - 3.2e-44 151.8 21.0 7.3e-44 150.6 14.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS82602.1 - 2.4e-07 30.1 3.3 0.0021 17.1 0.0 3.3 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Acetyltransf_10 PF13673.1 ETS82603.1 - 2.7e-10 40.3 0.4 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS82603.1 - 3.8e-08 33.3 0.0 1.9e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS82603.1 - 2.2e-06 27.5 0.1 4.9e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS82603.1 - 7.7e-05 22.5 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS82603.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 ETS82603.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cutinase PF01083.17 ETS82604.1 - 2.5e-45 154.3 2.3 8.3e-45 152.6 0.5 1.9 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.6 ETS82604.1 - 3.1e-05 23.5 0.1 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 ETS82604.1 - 0.0021 17.9 0.3 0.0027 17.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82604.1 - 0.003 17.1 0.1 0.0045 16.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 ETS82604.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 ETS82604.1 - 0.039 13.7 0.3 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Maff2 PF12750.2 ETS82604.1 - 0.047 13.2 1.4 1.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Maff2 family Thioesterase PF00975.15 ETS82604.1 - 0.078 13.1 0.2 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF4210 PF13915.1 ETS82605.1 - 1.1e-25 89.6 0.0 2.7e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 ETS82605.1 - 4e-21 74.6 0.6 8.3e-21 73.6 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 ETS82606.1 - 0.018 14.8 44.0 0.94 9.2 11.6 2.5 1 1 1 2 2 2 0 rRNA processing DUF605 PF04652.11 ETS82606.1 - 1.9 7.7 24.2 2.5 7.3 16.8 1.1 1 0 0 1 1 1 0 Vta1 like RhoGAP PF00620.22 ETS82607.1 - 5.5e-46 155.9 0.0 5.5e-46 155.9 0.0 3.0 3 1 1 4 4 4 1 RhoGAP domain LIM PF00412.17 ETS82607.1 - 9.3e-15 54.4 17.6 3.4e-09 36.6 1.2 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 ETS82607.1 - 4.6 7.2 19.3 0.37 10.7 1.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain Myosin_head PF00063.16 ETS82608.1 - 0.35 8.8 2.7 0.47 8.4 1.9 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Peptidase_C12 PF01088.16 ETS82609.1 - 2.6e-62 209.7 0.0 3.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Abhydrolase_6 PF12697.2 ETS82611.1 - 2.9e-26 92.7 0.1 7.1e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82611.1 - 3e-13 49.8 0.0 2.7e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82611.1 - 1.2e-12 47.7 0.0 1.2e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 ETS82611.1 - 0.00012 21.2 0.0 0.00024 20.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 ETS82611.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 ETS82611.1 - 0.0017 18.1 0.1 0.0054 16.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 ETS82611.1 - 0.0083 15.5 0.0 0.068 12.5 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 ETS82611.1 - 0.0089 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 ETS82611.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 ETS82611.1 - 0.018 15.2 1.0 0.096 12.9 0.1 2.5 2 1 0 2 2 2 0 Thioesterase domain Abhydrolase_3 PF07859.8 ETS82611.1 - 0.037 13.5 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 ETS82611.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase PF07224.6 ETS82611.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase OB_NTP_bind PF07717.11 ETS82612.1 - 1e-27 96.2 0.0 5.8e-27 93.7 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS82612.1 - 6.1e-27 93.6 0.2 6.1e-27 93.6 0.1 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS82612.1 - 6.6e-13 48.3 0.0 2.2e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 ETS82612.1 - 6.3e-11 42.2 0.7 1.2e-10 41.2 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 ETS82612.1 - 1.1e-08 34.7 0.1 2.8e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 ETS82612.1 - 1.3e-05 24.2 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 ETS82612.1 - 4.1e-05 23.7 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS82612.1 - 0.011 16.0 0.2 0.47 10.7 0.1 2.8 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.1 ETS82612.1 - 0.012 15.5 0.3 0.088 12.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS82612.1 - 0.017 14.8 0.1 0.062 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 ETS82612.1 - 0.039 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 ETS82612.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 ETS82612.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 ETS82612.1 - 0.13 12.6 0.3 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PBP_like_2 PF12849.2 ETS82612.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain Herpes_ori_bp PF02399.10 ETS82612.1 - 0.14 10.0 0.0 0.23 9.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Myosin_head PF00063.16 ETS82612.1 - 0.27 9.2 0.0 0.43 8.5 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Pmp3 PF01679.12 ETS82613.1 - 5.1e-19 67.7 7.9 6.8e-19 67.3 5.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SUV3_C PF12513.3 ETS82616.1 - 1.3e-15 56.5 0.8 3.4e-15 55.1 0.6 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 ETS82616.1 - 7.9e-09 35.2 0.1 2.3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.16 ETS82617.1 - 9.7e-33 111.6 1.4 1.4e-32 111.1 1.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 ETS82617.1 - 3.5e-20 71.3 0.0 6.1e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 ETS82617.1 - 0.071 13.4 0.1 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 SpoIIAA-like FtsQ PF03799.10 ETS82618.1 - 0.098 12.8 0.1 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 Cell division protein FtsQ adh_short PF00106.20 ETS82619.1 - 7.2e-11 42.2 0.0 2.7e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS82619.1 - 4.9e-06 26.3 0.1 1.4e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS82619.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2570 PF10828.3 ETS82619.1 - 0.0035 16.9 0.8 0.0067 16.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) adh_short_C2 PF13561.1 ETS82619.1 - 0.0096 15.7 0.0 0.067 12.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase G-patch PF01585.18 ETS82620.1 - 7.5e-10 38.4 0.7 1.3e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 ETS82620.1 - 0.049 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site Sec1 PF00995.18 ETS82621.1 - 1.4e-134 449.8 0.0 1.5e-134 449.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 ETS82621.1 - 0.033 13.5 0.1 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) DSPc PF00782.15 ETS82622.1 - 3.3e-15 55.8 0.1 5.4e-14 51.9 0.1 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 ETS82622.1 - 0.016 15.4 0.1 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 ETS82622.1 - 0.062 12.1 0.1 0.09 11.6 0.0 1.4 1 1 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Spo7 PF03907.8 ETS82623.1 - 1.2e-69 234.1 0.0 1.6e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein PAN_4 PF14295.1 ETS82624.1 - 0.0077 15.9 0.3 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 PAN domain GATA PF00320.22 ETS82625.1 - 4.4e-15 54.7 2.5 7.6e-15 53.9 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Rootletin PF15035.1 ETS82625.1 - 0.014 15.3 15.4 0.05 13.5 10.5 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion AAA_23 PF13476.1 ETS82625.1 - 0.035 14.4 2.0 0.051 13.8 1.4 1.3 1 0 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.7 ETS82625.1 - 0.094 12.0 0.3 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding HAUS-augmin3 PF14932.1 ETS82625.1 - 0.11 11.6 12.9 0.18 10.9 8.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 eIF-5_eIF-2B PF01873.12 ETS82625.1 - 0.15 11.7 0.4 0.31 10.7 0.3 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 CENP-F_leu_zip PF10473.4 ETS82625.1 - 0.26 11.1 18.3 0.11 12.3 2.5 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tweety PF04906.8 ETS82625.1 - 0.32 9.3 1.4 0.5 8.7 0.1 1.7 1 1 1 2 2 2 0 Tweety HlyD_2 PF12700.2 ETS82625.1 - 0.44 9.6 6.0 0.63 9.1 4.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Fib_alpha PF08702.5 ETS82625.1 - 1 9.5 7.9 2 8.5 5.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 ETS82625.1 - 1 9.2 19.1 5.5 6.8 3.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ArfGap PF01412.13 ETS82625.1 - 1 9.1 3.7 0.4 10.4 0.1 2.1 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf Macoilin PF09726.4 ETS82625.1 - 1.1 7.4 12.6 2.2 6.4 8.7 1.4 1 0 0 1 1 1 0 Transmembrane protein Striatin PF08232.7 ETS82625.1 - 1.6 9.0 18.8 7.8 6.8 3.7 2.4 1 1 1 2 2 2 0 Striatin family DUF4200 PF13863.1 ETS82625.1 - 9.7 6.1 22.5 4.3 7.2 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) KH_1 PF00013.24 ETS82626.1 - 0.0055 16.3 0.0 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 ETS82626.1 - 0.031 13.9 0.0 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 KH domain Bystin PF05291.6 ETS82627.1 - 4.2e-121 403.5 0.0 5.6e-121 403.1 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 ETS82628.1 - 1.2e-64 217.3 0.2 3.5e-64 215.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 ETS82628.1 - 3.5e-22 77.7 0.4 8.5e-22 76.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 ETS82628.1 - 0.0068 14.7 0.0 0.045 12.0 0.0 2.2 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Sugar_tr PF00083.19 ETS82629.1 - 1.5e-50 172.0 22.6 2.2e-50 171.5 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82629.1 - 7.9e-21 74.1 26.0 7.9e-21 74.1 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF427 PF04248.7 ETS82630.1 - 6.8e-30 102.5 1.6 7.6e-30 102.4 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) FMN_dh PF01070.13 ETS82631.1 - 3.7e-121 404.3 0.3 4.6e-121 404.0 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS82631.1 - 9.7e-24 82.9 0.0 1.8e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS82631.1 - 2.6e-07 29.9 0.1 5.2e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS82631.1 - 6.5e-05 21.9 0.2 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS82631.1 - 0.00081 18.6 0.1 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS82631.1 - 0.0026 17.0 0.5 0.13 11.5 0.0 2.4 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 ETS82631.1 - 0.018 14.1 0.2 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 ETS82631.1 - 0.086 11.7 0.1 1.4 7.7 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF561) Cullin PF00888.17 ETS82632.1 - 7e-203 675.3 10.1 1.1e-202 674.8 7.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETS82632.1 - 1.1e-27 95.6 3.7 1.1e-27 95.6 2.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Sec23_BS PF08033.7 ETS82634.1 - 0.045 14.2 0.1 0.15 12.6 0.1 1.8 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain Virul_fac_BrkB PF03631.10 ETS82634.1 - 0.1 11.9 7.1 0.17 11.2 2.0 2.2 1 1 1 2 2 2 0 Virulence factor BrkB COX2-transmemb PF09125.5 ETS82634.1 - 0.14 11.7 0.1 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Glycos_transf_4 PF00953.16 ETS82635.1 - 4.3e-30 104.6 12.2 4.3e-30 104.6 8.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 PHD PF00628.24 ETS82636.1 - 5.8e-08 32.2 7.7 1.1e-07 31.4 5.3 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 ETS82636.1 - 1.2e-07 32.1 0.1 6.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 SET domain DUF619 PF04768.8 ETS82637.1 - 1.4e-48 164.4 0.0 2.4e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) HSP70 PF00012.15 ETS82638.1 - 1.9e-170 567.7 2.7 2.6e-170 567.2 1.9 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS82638.1 - 1.3e-12 46.9 0.0 4.3e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 ETS82638.1 - 0.0014 18.4 1.4 0.75 9.6 0.0 3.7 2 2 0 2 2 2 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 ETS82638.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain BAGE PF08180.6 ETS82638.1 - 3.8 7.3 6.1 45 3.9 0.1 3.6 4 0 0 4 4 4 0 B melanoma antigen family WD40 PF00400.27 ETS82641.1 - 4.9e-17 61.0 0.1 3.2e-05 23.6 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Glyco_hydro_6 PF01341.12 ETS82642.1 - 2.2e-90 303.1 2.3 2.5e-90 302.9 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 THDPS_N PF14790.1 ETS82642.1 - 0.058 13.0 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal adh_short_C2 PF13561.1 ETS82643.1 - 2.3e-27 96.3 1.0 2.7e-27 96.0 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS82643.1 - 1.2e-25 90.3 2.1 1.5e-25 90.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82643.1 - 1e-13 51.3 0.7 1.5e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82643.1 - 0.0052 16.2 0.4 0.0072 15.7 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 ETS82644.1 - 5.7e-31 106.4 3.8 9.2e-31 105.8 0.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82644.1 - 5.5e-19 67.9 0.3 1.3e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS82644.1 - 2.9e-06 28.2 0.0 7.4e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 ETS82644.1 - 0.00011 20.8 0.0 0.00016 20.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 ETS82644.1 - 0.00014 21.4 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 ETS82644.1 - 0.0023 17.5 0.1 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETS82644.1 - 0.0034 17.5 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 ETS82644.1 - 0.011 15.6 0.2 0.044 13.6 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 ETS82644.1 - 0.022 15.1 1.1 0.058 13.7 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 ETS82644.1 - 0.024 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.15 ETS82644.1 - 0.059 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus XdhC_C PF13478.1 ETS82644.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain PRK PF00485.13 ETS82645.1 - 3.2e-10 39.9 0.0 4.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 ETS82645.1 - 7.5e-10 39.6 0.0 3e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS82645.1 - 1.1e-06 29.0 0.0 2.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS82645.1 - 2.7e-06 27.3 0.7 3e-05 23.9 0.5 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS82645.1 - 8.1e-06 25.0 0.0 1.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 ETS82645.1 - 0.00011 22.2 0.0 0.00013 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 ETS82645.1 - 0.00012 22.2 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS82645.1 - 0.00049 20.2 0.0 0.00083 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETS82645.1 - 0.00077 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 ETS82645.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETS82645.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 ETS82645.1 - 0.0031 17.4 0.0 0.009 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 ETS82645.1 - 0.0045 16.6 0.0 0.016 14.9 0.0 1.8 2 1 1 3 3 3 1 Adenylylsulphate kinase NTPase_1 PF03266.10 ETS82645.1 - 0.011 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 ETS82645.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF3987 PF13148.1 ETS82645.1 - 0.014 13.9 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_14 PF13173.1 ETS82645.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 ETS82645.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 ETS82645.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETS82645.1 - 0.018 14.5 0.3 0.073 12.6 0.0 2.2 2 0 0 2 2 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS82645.1 - 0.021 15.1 0.0 0.08 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 ETS82645.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 ETS82645.1 - 0.023 14.0 0.0 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.1 ETS82645.1 - 0.027 14.0 1.3 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 ETS82645.1 - 0.031 13.3 0.1 0.066 12.2 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 ETS82645.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SKI PF01202.17 ETS82645.1 - 0.032 14.0 0.0 0.088 12.6 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase Cytidylate_kin2 PF13189.1 ETS82645.1 - 0.033 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Rad17 PF03215.10 ETS82645.1 - 0.055 12.1 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 ETS82645.1 - 0.063 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 ETS82645.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 ETS82645.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.17 ETS82645.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase CoaE PF01121.15 ETS82645.1 - 0.16 11.3 0.8 1.4 8.3 0.0 2.4 2 1 1 3 3 3 0 Dephospho-CoA kinase adh_short_C2 PF13561.1 ETS82646.1 - 1.5e-26 93.6 0.0 1.8e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS82646.1 - 1.1e-25 90.5 7.5 1.5e-25 90.0 5.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82646.1 - 4.5e-14 52.5 3.0 6.1e-14 52.0 2.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS82646.1 - 0.0021 17.0 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS82646.1 - 0.0027 17.1 0.4 0.0057 16.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS82646.1 - 0.0033 16.1 0.1 0.0043 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 ETS82647.1 - 4.3e-128 427.7 24.5 5.1e-128 427.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82647.1 - 3.2e-25 88.6 42.5 2.3e-16 59.4 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS82648.1 - 5.7e-29 100.7 0.0 9.4e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82648.1 - 5.4e-08 32.6 7.2 8.8e-08 31.9 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 ETS82648.1 - 0.044 13.7 0.1 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Aldo_ket_red PF00248.16 ETS82649.1 - 2.1e-52 177.7 0.0 2.5e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_28 PF13518.1 ETS82649.1 - 0.056 13.4 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Sld5 PF05916.6 ETS82650.1 - 3e-24 85.3 0.0 4.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein SNF2_N PF00176.18 ETS82652.1 - 1.6e-67 227.4 0.5 2.9e-67 226.5 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS82652.1 - 1.6e-16 59.9 0.3 6.3e-16 58.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS82652.1 - 5e-07 29.7 0.0 1.8e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RR_TM4-6 PF06459.7 ETS82652.1 - 0.0058 16.5 2.5 0.0058 16.5 1.7 2.3 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 AT_hook PF02178.14 ETS82652.1 - 0.019 14.6 1.9 0.019 14.6 1.3 3.0 2 0 0 2 2 2 0 AT hook motif DUF2239 PF09998.4 ETS82652.1 - 0.039 13.5 4.5 0.21 11.1 0.4 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Latarcin PF10279.4 ETS82652.1 - 0.57 10.4 7.4 0.71 10.0 0.2 2.9 2 0 0 2 2 2 0 Latarcin precursor TFIIA_gamma_N PF02268.11 ETS82653.1 - 4.2e-26 90.2 0.3 6e-26 89.7 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 ETS82653.1 - 2.4e-25 88.0 1.7 3.4e-25 87.6 1.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit EmrE PF13536.1 ETS82654.1 - 4.3e-05 23.6 1.6 4.3e-05 23.6 1.1 1.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 ETS82654.1 - 0.00037 20.5 9.4 0.00064 19.7 6.0 1.8 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 ETS82654.1 - 0.025 14.3 1.8 0.039 13.7 1.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Med13_C PF06333.7 ETS82654.1 - 0.12 10.9 4.5 0.14 10.6 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Voltage_CLC PF00654.15 ETS82655.1 - 1.5e-88 297.2 30.3 1.5e-88 297.2 21.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 ETS82655.1 - 1.2e-13 50.6 0.3 4.1e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 ETS82656.1 - 4.6e-13 49.0 2.0 5.9e-13 48.6 0.4 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS82656.1 - 0.00011 22.2 0.1 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3708 PF12501.3 ETS82656.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter LRR_9 PF14580.1 ETS82657.1 - 2.2e-46 157.6 0.2 3.3e-46 157.0 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 ETS82657.1 - 4.3e-06 26.2 5.8 0.0053 16.3 2.8 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS82657.1 - 1e-05 25.1 5.4 0.00014 21.5 1.0 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 ETS82657.1 - 0.015 15.3 2.3 43 4.9 0.2 4.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 ETS82657.1 - 0.031 14.3 0.2 92 3.6 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 ETS82657.1 - 0.04 13.9 4.1 58 4.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 ETS82657.1 - 1.6 7.9 3.8 0.68 9.1 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) GATase PF00117.23 ETS82658.1 - 2.8e-09 36.7 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Bd3614_N PF14442.1 ETS82658.1 - 0.11 12.4 0.2 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal GPI-anchored PF10342.4 ETS82659.1 - 1.2e-05 25.6 0.8 2.1e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lactonase PF10282.4 ETS82660.1 - 1.4e-83 280.8 0.0 1.6e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.13 ETS82661.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS82661.1 - 7e-08 31.6 0.1 1.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_A4 PF01828.12 ETS82662.1 - 1.8e-57 193.7 11.5 1.8e-57 193.7 8.0 1.7 2 0 0 2 2 2 1 Peptidase A4 family Macoilin PF09726.4 ETS82662.1 - 0.43 8.7 2.9 0.39 8.9 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Pec_lyase_C PF00544.14 ETS82663.1 - 7.4e-12 45.1 4.6 1.3e-11 44.3 3.2 1.4 1 0 0 1 1 1 1 Pectate lyase NgoMIV_restric PF09015.5 ETS82663.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme adh_short PF00106.20 ETS82665.1 - 4.5e-13 49.4 0.0 8.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82665.1 - 2.6e-10 40.4 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82665.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox_3 PF13738.1 ETS82666.1 - 2.2e-22 80.1 0.0 1.2e-21 77.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS82666.1 - 2.4e-15 55.7 0.0 3.2e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS82666.1 - 1.2e-10 41.2 0.0 2.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS82666.1 - 6.4e-10 38.4 0.0 4.3e-05 22.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS82666.1 - 1.4e-09 37.9 0.0 3.6e-07 30.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 ETS82666.1 - 1.4e-07 30.7 0.3 0.00018 20.5 0.0 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS82666.1 - 7.6e-06 25.9 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS82666.1 - 0.031 13.3 0.0 0.092 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family AA_permease_2 PF13520.1 ETS82667.1 - 1.7e-60 204.7 44.7 2.1e-60 204.4 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS82667.1 - 6.7e-24 84.0 39.3 9.2e-24 83.6 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 ETS82668.1 - 1.9e-14 53.2 1.8 3.4e-14 52.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82668.1 - 0.00045 20.0 12.8 0.00045 20.0 8.9 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1989 PF09347.5 ETS82669.1 - 1.2e-50 171.2 0.0 2e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 ETS82669.1 - 1.9e-19 69.4 0.0 3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 ETS82669.1 - 0.0061 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Beta-lactamase PF00144.19 ETS82670.1 - 3.4e-35 121.6 0.1 4.1e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 ETS82670.1 - 0.022 14.0 0.2 0.074 12.3 0.2 1.8 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.17 ETS82671.1 - 2.7e-41 141.5 0.0 4.3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS82673.1 - 1.2e-52 178.9 0.0 1.7e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribonuc_L-PSP PF01042.16 ETS82674.1 - 9.1e-16 57.7 0.0 1.3e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 ETS82674.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) SMK-1 PF04802.10 ETS82676.1 - 6.2e-76 254.2 6.6 6.2e-76 254.2 4.5 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 ADH_zinc_N PF00107.21 ETS82677.1 - 1.6e-18 66.5 0.1 2.3e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS82677.1 - 1.4e-08 35.6 0.0 3.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS82677.1 - 0.0083 15.8 0.0 0.023 14.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sulf_transp PF04143.9 ETS82678.1 - 1.4e-14 53.8 25.5 1.3e-10 41.0 5.0 3.9 4 1 0 4 4 4 2 Sulphur transport DUF4516 PF14990.1 ETS82678.1 - 7.2 6.2 6.4 4.6 6.8 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) FAD_binding_4 PF01565.18 ETS82679.1 - 2.8e-12 46.3 0.0 5.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS82679.1 - 9.9e-05 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 ETS82680.1 - 2.1e-11 44.0 0.6 1.4e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS82680.1 - 0.00012 21.7 0.1 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain HET PF06985.6 ETS82681.1 - 0.00058 20.0 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L34 PF00468.12 ETS82681.1 - 0.19 11.4 0.8 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L34 Dioxygenase_C PF00775.16 ETS82682.1 - 1e-08 34.6 0.1 1.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Ank_2 PF12796.2 ETS82683.1 - 1.6e-48 162.9 0.7 2.9e-16 59.5 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82683.1 - 1.5e-39 131.8 4.6 2.5e-06 27.0 0.1 9.9 9 1 1 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 ETS82683.1 - 3.9e-28 97.3 3.3 1.2e-05 25.6 0.0 8.2 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82683.1 - 1.8e-24 83.3 1.8 0.0023 18.0 0.0 8.7 9 0 0 9 9 8 5 Ankyrin repeat Ank_5 PF13857.1 ETS82683.1 - 2e-24 85.0 5.0 0.0002 21.5 0.1 7.9 1 1 8 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.7 ETS82683.1 - 6.1e-10 38.9 0.1 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 ETS82683.1 - 1.3e-07 30.8 0.4 9.7e-07 27.9 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.1 ETS82683.1 - 6.2e-06 26.1 0.0 0.0021 17.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETS82683.1 - 0.00051 18.9 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 ETS82683.1 - 0.00057 19.6 0.1 0.0027 17.4 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 ETS82683.1 - 0.0019 18.2 0.0 0.0059 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS82683.1 - 0.0032 17.6 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS82683.1 - 0.013 15.7 0.0 0.041 14.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETS82683.1 - 0.015 15.4 0.0 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MFS_1 PF07690.11 ETS82684.1 - 3.8e-33 114.6 28.5 3.8e-33 114.6 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82684.1 - 4.5e-11 42.0 8.4 4.5e-11 42.0 5.8 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 ETS82685.1 - 2.4e-25 88.8 0.1 4.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82685.1 - 1.4e-08 34.4 10.6 3.2e-08 33.3 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.18 ETS82686.1 - 1.2e-77 261.0 43.5 1e-39 136.6 10.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS82686.1 - 2.5e-62 209.1 0.0 2.9e-31 108.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 ETS82686.1 - 4.7e-13 48.8 0.0 0.0042 16.3 0.0 3.9 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS82686.1 - 3.6e-11 43.5 0.0 0.017 15.1 0.0 4.3 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 ETS82686.1 - 1.5e-09 37.2 0.6 2.2e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS82686.1 - 1.1e-07 32.6 0.0 0.0038 18.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 ETS82686.1 - 1.9e-07 30.0 0.5 0.0026 16.4 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 ETS82686.1 - 2.5e-07 30.0 0.0 0.013 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS82686.1 - 3e-07 30.6 0.5 0.14 12.3 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS82686.1 - 4.3e-07 30.1 4.7 0.0066 16.4 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 ETS82686.1 - 1.6e-06 28.3 1.2 0.91 9.7 0.0 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS82686.1 - 1.1e-05 24.9 0.3 0.11 11.8 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_19 PF13245.1 ETS82686.1 - 2.3e-05 24.0 0.1 0.35 10.6 0.0 4.0 3 1 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 ETS82686.1 - 9.7e-05 21.8 0.2 1.2 8.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 ETS82686.1 - 0.0001 22.0 0.0 0.92 9.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 ETS82686.1 - 0.00012 22.4 0.4 0.69 10.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 ETS82686.1 - 0.00014 21.7 2.0 0.67 9.9 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 ETS82686.1 - 0.00026 20.8 0.0 0.6 9.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 ETS82686.1 - 0.00069 19.2 0.1 5.2 6.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 ETS82686.1 - 0.00091 19.5 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETS82686.1 - 0.0015 17.9 0.1 1.8 7.9 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein MobB PF03205.9 ETS82686.1 - 0.0028 17.3 0.1 2.7 7.7 0.0 3.1 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS82686.1 - 0.003 17.4 0.0 4.6 7.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.17 ETS82686.1 - 0.004 16.6 0.2 3 7.2 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 ETS82686.1 - 0.0048 16.5 0.0 0.31 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 ETS82686.1 - 0.0059 16.1 2.6 2.2 7.7 0.0 3.8 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 ETS82686.1 - 0.015 15.3 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 ETS82686.1 - 0.016 14.7 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 ETS82686.1 - 0.051 13.7 0.0 9.1 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 ETS82686.1 - 0.088 12.7 0.1 25 4.8 0.0 3.3 4 0 0 4 4 3 0 50S ribosome-binding GTPase Rad17 PF03215.10 ETS82686.1 - 0.13 10.8 0.1 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_15 PF13175.1 ETS82686.1 - 0.43 9.5 0.0 5.9 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zn_clus PF00172.13 ETS82687.1 - 6.3e-08 32.3 10.3 1.1e-07 31.6 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.6 ETS82688.1 - 2.7e-104 349.5 1.0 3.3e-104 349.2 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase COesterase PF00135.23 ETS82689.1 - 9.2e-23 80.7 0.1 5.6e-22 78.1 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS82689.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold gpD PF02925.11 ETS82689.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D HgmA PF04209.8 ETS82691.1 - 1.3e-119 399.4 0.0 1.5e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Glyco_hydro_18 PF00704.23 ETS82692.1 - 1.5e-41 142.9 13.9 3.7e-41 141.7 9.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 ETS82692.1 - 8.1e-15 54.4 0.8 0.00038 20.2 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 ETS82692.1 - 0.00032 20.6 4.4 0.00032 20.6 3.0 4.1 4 0 0 4 4 4 1 Chitin recognition protein UPF0118 PF01594.11 ETS82692.1 - 0.97 8.3 4.1 1.8 7.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 Ank_2 PF12796.2 ETS82694.1 - 1.7e-28 98.7 0.1 1.1e-10 41.6 0.1 5.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS82694.1 - 6.9e-25 86.9 4.6 1.5e-08 34.8 0.0 7.5 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 ETS82694.1 - 7.2e-20 69.7 9.9 1.1e-05 24.9 0.0 9.0 8 2 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 ETS82694.1 - 1.4e-17 63.3 3.1 5.5e-06 26.4 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82694.1 - 8.9e-17 59.5 1.2 3e-05 23.8 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat DUF2564 PF10819.3 ETS82696.1 - 0.0076 16.3 4.1 0.0076 16.3 2.8 4.3 3 2 1 4 4 4 1 Protein of unknown function (DUF2564) DUF4456 PF14644.1 ETS82696.1 - 0.023 13.9 11.4 0.15 11.2 7.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4456) DUF2580 PF10824.3 ETS82696.1 - 0.039 14.3 10.1 0.058 13.7 3.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) Baculo_PEP_C PF04513.7 ETS82696.1 - 0.053 13.3 1.7 3.4 7.4 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 ETS82696.1 - 0.053 13.0 11.5 0.45 9.9 7.8 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.5 ETS82696.1 - 0.064 13.1 6.2 4.1 7.3 0.1 3.9 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) LUC7 PF03194.10 ETS82696.1 - 0.13 11.7 10.8 0.57 9.6 4.2 2.2 1 1 1 2 2 2 0 LUC7 N_terminus DUF3584 PF12128.3 ETS82696.1 - 0.18 9.1 17.7 0.018 12.3 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.1 ETS82696.1 - 0.18 11.1 5.7 1.8 7.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3994 PF13159.1 ETS82696.1 - 0.3 11.3 3.3 5.2 7.3 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) AAA_13 PF13166.1 ETS82696.1 - 0.31 9.4 10.3 0.4 9.0 7.1 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 ETS82696.1 - 0.39 10.6 16.4 2.1 8.2 1.8 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.6 ETS82696.1 - 0.41 11.0 8.3 1.1 9.7 1.4 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal OEP PF02321.13 ETS82696.1 - 0.97 9.0 13.3 0.13 11.7 1.0 3.3 2 1 1 3 3 3 0 Outer membrane efflux protein MxiH PF09392.5 ETS82696.1 - 5.1 7.7 7.1 95 3.6 3.4 3.4 1 1 1 2 2 2 0 Type III secretion needle MxiH like HET PF06985.6 ETS82697.1 - 5.9e-28 97.7 0.9 2.2e-27 95.9 0.8 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) B_lectin PF01453.19 ETS82698.1 - 2.4e-28 98.2 7.4 6.9e-08 32.3 0.3 5.1 2 1 3 5 5 5 4 D-mannose binding lectin HET PF06985.6 ETS82698.1 - 7.7e-24 84.4 4.0 7.7e-24 84.4 2.8 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PQQ_3 PF13570.1 ETS82698.1 - 0.017 15.3 5.7 1.6 9.1 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Glyco_tran_WecB PF03808.8 ETS82699.1 - 0.081 12.3 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_S15 PF02129.13 ETS82700.1 - 7.3e-43 146.9 5.4 2.2e-39 135.5 0.7 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS82700.1 - 3.3e-21 76.1 0.8 5.9e-21 75.3 0.6 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS82700.1 - 2.5e-06 27.5 0.1 9.4e-06 25.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 ETS82700.1 - 0.086 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Zn_clus PF00172.13 ETS82701.1 - 2.5e-08 33.7 12.4 4.4e-08 32.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS82701.1 - 2.8e-07 29.6 0.0 3.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL PF00657.17 ETS82703.1 - 3.1e-15 56.6 0.1 3.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peripla_BP_3 PF13377.1 ETS82703.1 - 0.0041 17.1 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein-like domain DUF1517 PF07466.6 ETS82705.1 - 0.001 18.1 6.7 0.0024 16.9 4.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 ETS82705.1 - 0.0081 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 ETS82705.1 - 0.017 14.6 1.2 0.032 13.7 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 ETS82705.1 - 0.049 13.2 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family DAG1 PF05454.6 ETS82705.1 - 0.086 12.0 0.1 0.086 12.0 0.1 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF566 PF04484.7 ETS82705.1 - 0.59 9.5 12.9 0.86 9.0 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3042 PF11240.3 ETS82705.1 - 1 9.1 2.6 2.9 7.7 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Thymidylat_synt PF00303.14 ETS82706.1 - 3.6e-117 390.1 0.0 4.1e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HTH_Tnp_Tc5 PF03221.11 ETS82707.1 - 2.7e-17 62.3 0.7 5.2e-16 58.2 0.1 2.7 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain KfrA_N PF11740.3 ETS82707.1 - 0.0015 18.9 3.7 0.0076 16.6 2.5 2.4 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term DUF737 PF05300.6 ETS82707.1 - 0.032 14.2 0.3 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SH3_1 PF00018.23 ETS82708.1 - 7.8e-27 92.4 0.0 4.9e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 ETS82708.1 - 1.3e-19 69.5 0.1 1.2e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 ETS82708.1 - 8.4e-14 51.3 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 ETS82708.1 - 5.5e-13 48.1 0.0 1.9e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 ETS82708.1 - 1.5e-07 30.9 0.2 2.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Glyco_hydro_17 PF00332.13 ETS82709.1 - 1.2e-05 24.5 0.1 1.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.7 ETS82710.1 - 4.2e-35 121.5 22.9 1.2e-34 120.1 15.9 1.7 1 1 0 1 1 1 1 Hamartin protein Semialdhyde_dhC PF02774.13 ETS82710.1 - 0.025 14.4 0.5 0.061 13.1 0.3 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF948 PF06103.6 ETS82710.1 - 4.2 7.2 7.3 3 7.7 0.3 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4066 PF13278.1 ETS82711.1 - 6.6e-20 71.0 0.2 4.3e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS82711.1 - 0.00015 21.2 0.0 0.00039 19.8 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Ribosomal_L23 PF00276.15 ETS82712.1 - 1.4e-11 44.1 0.0 2.5e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 Filament PF00038.16 ETS82713.1 - 8.4e-06 25.4 87.3 0.0015 18.0 13.3 4.3 2 1 1 3 3 3 2 Intermediate filament protein Myosin_tail_1 PF01576.14 ETS82713.1 - 2.5e-05 22.2 100.8 0.013 13.2 69.6 3.4 1 1 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 ETS82713.1 - 0.00039 19.0 75.3 0.0012 17.3 8.6 3.3 1 1 1 3 3 3 2 AAA domain DUF4200 PF13863.1 ETS82713.1 - 0.001 19.0 22.2 0.001 19.0 15.4 6.6 1 1 6 7 7 5 2 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 ETS82713.1 - 0.0012 18.6 99.8 0.0015 18.3 14.7 6.2 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 ETS82713.1 - 0.0046 16.7 10.3 0.0046 16.7 7.2 9.3 2 1 7 10 10 10 2 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 ETS82713.1 - 0.0059 16.4 25.9 0.0059 16.4 18.0 6.3 2 1 5 7 7 7 4 Tropomyosin like MscS_porin PF12795.2 ETS82713.1 - 0.0066 15.7 22.0 0.0066 15.7 15.2 4.4 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain HALZ PF02183.13 ETS82713.1 - 0.015 15.0 0.1 0.015 15.0 0.1 7.1 7 0 0 7 7 7 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 ETS82713.1 - 0.019 14.1 25.0 0.15 11.2 3.5 3.9 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 ETS82713.1 - 0.1 11.7 100.4 0.0072 15.4 33.5 5.1 1 1 5 6 6 6 0 Tropomyosin LigT_PEase PF02834.11 ETS82713.1 - 0.16 11.9 1.0 1.4 8.9 0.0 3.2 3 1 0 3 3 2 0 LigT like Phosphoesterase WEMBL PF05701.6 ETS82713.1 - 0.31 9.4 96.0 3.6 5.9 17.6 4.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light GAS PF13851.1 ETS82713.1 - 0.56 9.3 94.3 0.063 12.4 14.2 4.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 ETS82713.1 - 1.8 5.8 83.4 5.1 4.2 14.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 ETS82713.1 - 4.7 5.3 80.5 0.11 10.7 33.5 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) adh_short PF00106.20 ETS82714.1 - 4.3e-31 108.0 5.2 5.8e-31 107.6 3.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82714.1 - 5.7e-17 62.2 0.1 6.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82714.1 - 1.4e-11 44.3 2.7 2.1e-11 43.8 1.9 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 ETS82714.1 - 1.7e-06 27.5 1.5 3.8e-06 26.3 0.9 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS82714.1 - 9.2e-06 25.7 2.9 1.7e-05 24.8 1.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 ETS82714.1 - 2.7e-05 23.7 0.9 4.8e-05 22.9 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.10 ETS82714.1 - 0.0022 17.6 0.2 0.0038 16.8 0.2 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein FAD_binding_3 PF01494.14 ETS82714.1 - 0.0056 15.7 0.1 0.0073 15.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 ETS82714.1 - 0.017 14.3 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 ETS82714.1 - 0.029 13.5 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 ETS82714.1 - 0.03 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 ETS82714.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 ETS82714.1 - 0.094 12.1 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MT-A70 PF05063.9 ETS82715.1 - 4.3e-30 104.5 0.9 5.5e-30 104.2 0.1 1.5 2 0 0 2 2 2 1 MT-A70 Methyltransf_26 PF13659.1 ETS82715.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 ETS82715.1 - 0.073 12.4 0.0 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF221 PF02714.10 ETS82716.1 - 3.6e-103 344.8 22.2 3.6e-103 344.8 15.4 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS82716.1 - 1.6e-40 138.2 0.4 1.6e-40 138.2 0.3 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 ETS82716.1 - 2.2e-16 59.5 0.0 6.4e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 ETS82716.1 - 1.2e-09 38.5 14.0 0.00014 22.3 6.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) DUF3981 PF13139.1 ETS82716.1 - 0.076 13.0 1.9 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) CopD PF05425.8 ETS82716.1 - 4.4 7.5 16.5 4 7.6 3.9 3.6 3 1 0 3 3 3 0 Copper resistance protein D FAD_binding_3 PF01494.14 ETS82717.1 - 1.7e-18 66.7 2.0 6.8e-15 54.9 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS82717.1 - 4e-05 23.5 0.2 0.00011 22.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS82717.1 - 0.00011 22.0 0.0 0.0018 18.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 ETS82717.1 - 0.0002 20.3 0.0 0.0044 15.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 ETS82717.1 - 0.0015 17.5 0.2 0.0062 15.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS82717.1 - 0.031 13.1 0.7 0.065 12.0 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 ETS82717.1 - 0.042 12.4 0.1 0.072 11.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.19 ETS82717.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS82717.1 - 0.052 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS82717.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS82717.1 - 0.18 11.3 0.3 0.39 10.2 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.13 ETS82718.1 - 1.1e-86 290.9 0.0 1.8e-45 155.3 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS82718.1 - 0.0033 16.3 0.4 0.11 11.3 0.1 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS82718.1 - 0.043 12.7 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase MFS_1 PF07690.11 ETS82719.1 - 1.4e-33 116.0 36.3 2.2e-33 115.4 25.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82719.1 - 1.2e-07 30.7 18.4 2.3e-06 26.4 12.8 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1129 PF06570.6 ETS82719.1 - 0.13 11.5 1.4 0.45 9.7 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) EMP70 PF02990.11 ETS82720.1 - 8.2e-165 549.1 4.1 2.2e-164 547.7 2.8 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 Mito_carr PF00153.22 ETS82721.1 - 1.7e-58 194.3 9.3 2.4e-20 72.0 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein EpsG PF14897.1 ETS82723.1 - 0.00072 18.5 2.6 0.0008 18.4 1.8 1.1 1 0 0 1 1 1 1 EpsG family DUF2649 PF10854.3 ETS82723.1 - 0.017 15.2 0.6 0.043 13.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) DUF843 PF05814.6 ETS82723.1 - 0.085 12.6 1.2 0.12 12.2 0.5 1.5 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) MerC PF03203.9 ETS82723.1 - 0.27 11.6 6.7 1.6 9.1 1.0 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein SdpI PF13630.1 ETS82723.1 - 0.91 9.2 8.5 0.5 10.1 0.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF4282 PF14110.1 ETS82723.1 - 1.3 9.2 7.3 1.8 8.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Glyco_hydro_cc PF11790.3 ETS82724.1 - 1.8e-08 34.1 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.12 ETS82724.1 - 4.5e-05 22.0 0.2 6.7e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 2OG-FeII_Oxy_2 PF13532.1 ETS82725.1 - 3.7e-31 108.4 0.0 5.1e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 ETS82725.1 - 8.3e-11 41.6 3.7 1.5e-10 40.8 2.6 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 ETS82725.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 CUE domain WD40 PF00400.27 ETS82726.1 - 5e-24 83.2 13.9 1.8e-07 30.7 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 ETS82726.1 - 0.065 13.0 0.0 0.43 10.3 0.0 2.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Lzipper-MIP1 PF14389.1 ETS82727.1 - 0.012 15.6 0.4 0.094 12.8 0.1 2.6 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 ETS82727.1 - 1.9 8.0 6.2 3.8 7.0 4.3 1.4 1 0 0 1 1 1 0 IncA protein SMN PF06003.7 ETS82729.1 - 6.4 5.7 9.5 3.5 6.6 5.3 1.5 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Fungal_trans PF04082.13 ETS82730.1 - 1.5e-29 102.6 0.0 2.1e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82730.1 - 1.2e-07 31.5 10.2 1.8e-07 30.9 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS82731.1 - 3.7e-38 131.1 26.9 2.9e-30 105.2 1.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82731.1 - 1.1e-12 47.2 1.8 1.1e-12 47.2 1.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS82731.1 - 1.8e-06 26.6 1.9 1.8e-06 26.6 1.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Transp_cyt_pur PF02133.10 ETS82732.1 - 1.2e-26 93.3 36.7 3.4e-26 91.7 24.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3353 PF11833.3 ETS82732.1 - 0.57 9.6 4.7 0.51 9.7 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) RibD_C PF01872.12 ETS82733.1 - 3.8e-36 124.5 0.0 4.6e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain HgmA PF04209.8 ETS82734.1 - 2.1e-132 441.5 0.0 2.6e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CYSTM PF12734.2 ETS82735.1 - 3.2e-08 33.4 16.3 3.2e-08 33.4 11.3 5.0 1 1 3 4 4 4 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 ETS82735.1 - 2.6 8.1 36.3 4.1 7.4 25.2 1.3 1 0 0 1 1 1 0 Proline-rich FAD_binding_3 PF01494.14 ETS82736.1 - 4e-24 85.3 0.1 7.4e-24 84.4 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS82736.1 - 2.4e-08 33.8 0.1 5.6e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS82736.1 - 5.9e-05 22.1 0.4 0.0016 17.3 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS82736.1 - 9.4e-05 21.4 0.8 0.00017 20.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS82736.1 - 0.00085 19.4 0.0 0.0019 18.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS82736.1 - 0.0012 18.7 1.2 0.003 17.4 0.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS82736.1 - 0.0018 17.1 1.2 0.0028 16.5 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 ETS82736.1 - 0.0036 16.4 0.1 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 ETS82736.1 - 0.0058 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase ThiF PF00899.16 ETS82736.1 - 0.009 15.8 0.1 0.025 14.3 0.1 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 ETS82736.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS82736.1 - 0.049 14.0 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 ETS82736.1 - 0.07 12.4 0.3 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 ETS82736.1 - 0.14 10.7 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 ETS82736.1 - 0.16 10.3 0.3 0.25 9.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein PfkB PF00294.19 ETS82737.1 - 7e-52 176.4 1.3 9.4e-52 176.0 0.9 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UQ_con PF00179.21 ETS82738.1 - 1e-09 37.9 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cas_Csa5 PF09702.5 ETS82738.1 - 0.16 12.0 0.0 17 5.5 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) BRE PF06113.7 ETS82738.1 - 0.17 10.8 0.1 0.25 10.3 0.1 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) MFS_1 PF07690.11 ETS82739.1 - 4.7e-21 74.9 69.0 7e-17 61.1 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_2 PF07883.6 ETS82740.1 - 3.3e-10 39.2 0.6 5.6e-10 38.5 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS82740.1 - 5.1e-05 22.9 0.2 6e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 ETS82740.1 - 0.00029 20.1 0.3 0.00052 19.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS82740.1 - 0.00073 19.2 0.6 0.00098 18.8 0.4 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 ETS82740.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Pirin PF02678.11 ETS82740.1 - 0.0052 16.6 1.8 0.084 12.7 0.2 2.1 1 1 1 2 2 2 1 Pirin Cupin_7 PF12973.2 ETS82740.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 ChrR Cupin-like domain DUF4082 PF13313.1 ETS82740.1 - 0.017 14.5 0.2 0.064 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) DUF3425 PF11905.3 ETS82741.1 - 1.1e-26 93.3 0.0 2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.12 ETS82741.1 - 0.02 15.1 6.3 0.034 14.4 4.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor ADH_N PF08240.7 ETS82742.1 - 9.1e-22 76.8 3.1 1.4e-21 76.3 2.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82742.1 - 5.6e-20 71.1 0.0 8.4e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS82742.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS82742.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 ETS82742.1 - 0.039 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 ETS82742.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N PF08240.7 ETS82743.1 - 1.9e-15 56.5 0.1 4.1e-15 55.4 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82743.1 - 5.6e-07 29.1 0.3 6.2e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 ETS82743.1 - 0.0093 15.6 0.2 0.0093 15.6 0.1 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated DUF1014 PF06244.7 ETS82744.1 - 1.3e-22 80.2 11.5 4.4e-22 78.5 8.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) SNF2_N PF00176.18 ETS82745.1 - 1.8e-64 217.3 0.2 2.8e-64 216.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS82745.1 - 2.6e-10 40.0 0.0 5.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS82745.1 - 0.00029 20.3 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS82745.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 ETS82745.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 NACHT PF05729.7 ETS82746.1 - 1.4e-06 28.1 0.7 1.3e-05 24.9 0.2 2.6 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 ETS82746.1 - 0.036 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain GFA PF04828.9 ETS82747.1 - 3.3e-13 49.3 7.5 1.1e-07 31.6 0.1 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 ETS82747.1 - 0.43 10.3 0.1 0.43 10.3 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal Myb_Cef PF11831.3 ETS82748.1 - 2.8e-50 170.6 9.2 2.8e-50 170.6 6.4 4.0 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 ETS82748.1 - 9.9e-23 79.9 5.8 1.3e-10 41.1 0.5 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS82748.1 - 1.1e-20 73.4 9.2 7.3e-15 54.8 2.6 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 ETS82748.1 - 0.0072 16.1 0.4 0.086 12.7 0.0 2.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.11 ETS82749.1 - 9.8e-42 142.9 45.0 9.8e-42 142.9 31.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS82749.1 - 3.9e-10 38.9 15.0 3.9e-10 38.9 10.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4305 PF14146.1 ETS82749.1 - 0.042 13.5 0.1 0.042 13.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) Hexokinase_1 PF00349.16 ETS82750.1 - 2.6e-27 95.5 0.0 3.4e-26 91.8 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 ETS82750.1 - 3.2e-18 65.8 0.0 1.2e-17 63.9 0.0 1.8 1 1 0 1 1 1 1 Hexokinase GILT PF03227.11 ETS82751.1 - 2.9e-15 56.0 0.1 4e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS_C PF11969.3 ETS82752.1 - 7.6e-31 106.7 2.1 1e-30 106.3 0.8 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 ETS82752.1 - 1e-22 80.5 0.0 2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Abhydrolase_6 PF12697.2 ETS82753.1 - 8e-26 91.3 0.1 9.3e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82753.1 - 5.6e-14 52.1 0.2 1.3e-13 50.9 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS82753.1 - 0.00086 18.2 0.0 0.0016 17.3 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 ETS82753.1 - 0.0011 18.5 0.4 0.49 9.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3089 PF11288.3 ETS82753.1 - 0.0052 15.9 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Chlorophyllase PF07224.6 ETS82753.1 - 0.023 13.4 0.1 0.045 12.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase DLH PF01738.13 ETS82753.1 - 0.052 12.8 0.1 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_43 PF04616.9 ETS82754.1 - 5.5e-106 353.8 1.4 1.4e-105 352.5 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Ank_2 PF12796.2 ETS82755.1 - 1.4e-70 233.6 0.0 2.7e-14 53.2 0.0 6.8 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82755.1 - 4e-56 184.1 8.2 7.1e-05 22.4 0.0 12.8 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 ETS82755.1 - 6.3e-52 172.4 12.8 2e-11 43.7 0.0 9.3 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82755.1 - 1.2e-45 148.9 2.1 0.00012 21.9 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 ETS82755.1 - 8.6e-40 134.4 5.4 2.7e-07 30.9 0.0 8.9 4 3 6 10 10 10 9 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 ETS82755.1 - 8.1e-14 51.1 3.2 7.4e-13 48.0 2.2 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 ETS82755.1 - 2.5e-07 30.5 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETS82755.1 - 2.3e-05 23.4 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 ETS82755.1 - 3.9e-05 23.8 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS82755.1 - 8.8e-05 22.5 0.6 0.0021 18.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 ETS82755.1 - 0.014 15.6 0.0 0.046 13.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2384 PF09722.5 ETS82755.1 - 0.043 13.6 0.0 15 5.5 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) DUF2075 PF09848.4 ETS82755.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) JAB PF01398.16 ETS82758.1 - 1.1e-07 31.5 0.1 5.8e-07 29.2 0.0 2.2 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 ETS82758.1 - 0.00019 21.5 0.3 0.00096 19.2 0.0 2.3 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function ADH_N PF08240.7 ETS82759.1 - 1e-27 96.0 0.5 2.3e-27 94.8 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS82759.1 - 6e-17 61.4 0.0 3.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ThiF PF00899.16 ETS82759.1 - 0.022 14.5 0.5 0.039 13.7 0.3 1.3 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 ETS82759.1 - 0.067 12.5 0.2 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 ETS82759.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Vps5 PF09325.5 ETS82760.1 - 1.2e-13 50.9 0.3 1.9e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 ETS82760.1 - 1.9e-08 34.0 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PX domain Med15 PF09606.5 ETS82760.1 - 0.017 13.3 19.7 0.026 12.7 13.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 ETS82760.1 - 0.25 10.7 17.9 0.4 10.0 12.4 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 ETS82760.1 - 1.5 6.9 20.2 2.3 6.3 14.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GTP_EFTU PF00009.22 ETS82761.1 - 1e-50 171.8 0.0 1.6e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 ETS82761.1 - 3e-19 68.6 0.0 7e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 ETS82761.1 - 5.3e-15 55.0 0.0 1.3e-13 50.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS82761.1 - 1.3e-06 28.3 0.0 7.3e-06 26.0 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 DUF615 PF04751.9 ETS82761.1 - 0.052 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Miro PF08477.8 ETS82761.1 - 0.085 13.3 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DivIVA PF05103.8 ETS82763.1 - 5.3 7.1 16.6 1.2 9.1 8.7 2.0 2 0 0 2 2 2 0 DivIVA protein Sugar_tr PF00083.19 ETS82764.1 - 4.3e-51 173.8 19.1 6.1e-51 173.4 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS82764.1 - 6.7e-20 71.0 26.2 1.2e-19 70.3 18.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2085 PF09858.4 ETS82764.1 - 3.4 7.7 6.9 0.49 10.5 0.9 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Abhydrolase_1 PF00561.15 ETS82765.1 - 5.9e-45 153.5 0.0 3.5e-44 151.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS82765.1 - 6.7e-15 55.5 0.4 4.8e-14 52.7 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82765.1 - 0.0041 16.8 0.0 0.037 13.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 ETS82765.1 - 0.013 15.3 0.1 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein DUF2424 PF10340.4 ETS82765.1 - 0.022 13.4 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Tho2 PF11262.3 ETS82766.1 - 7.9e-72 241.8 0.0 1.1e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 ETS82766.1 - 7.2e-26 89.7 0.0 5.1e-25 87.0 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Solute_trans_a PF03619.11 ETS82767.1 - 5.9e-81 271.7 18.1 7.3e-81 271.4 12.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.2 ETS82767.1 - 0.0042 17.2 1.3 0.0042 17.2 0.9 2.5 2 1 1 3 3 3 1 PrgI family protein PBP1_TM PF14812.1 ETS82767.1 - 0.15 12.4 3.3 0.36 11.1 2.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WSC PF01822.14 ETS82768.1 - 3.2e-13 49.4 13.3 3.2e-13 49.4 9.3 2.0 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 ETS82768.1 - 4.4e-06 25.8 0.2 1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 ETS82768.1 - 0.00024 20.6 3.3 0.00045 19.8 2.3 1.4 1 0 0 1 1 1 1 Podoplanin DUF2207 PF09972.4 ETS82768.1 - 0.16 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF347 PF03988.7 ETS82768.1 - 0.41 10.5 4.7 0.2 11.5 0.2 2.3 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Kelch_4 PF13418.1 ETS82769.1 - 0.049 13.4 10.0 1.9 8.3 0.1 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain Ldh_1_C PF02866.13 ETS82769.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Myosin_tail_1 PF01576.14 ETS82770.1 - 0.0056 14.4 10.9 0.011 13.5 7.6 1.3 1 0 0 1 1 1 1 Myosin tail DUF2205 PF10224.4 ETS82770.1 - 0.037 13.5 4.7 0.074 12.6 0.5 3.0 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 ETS82770.1 - 0.33 10.9 6.7 0.99 9.4 2.1 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.6 ETS82770.1 - 5.3 5.5 12.7 0.22 10.1 4.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Kinesin-relat_1 PF12711.2 ETS82770.1 - 6.8 7.1 10.7 65 4.0 4.7 3.0 2 1 0 2 2 2 0 Kinesin motor DUF221 PF02714.10 ETS82771.1 - 2.7e-104 348.5 24.7 2.7e-104 348.5 17.1 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS82771.1 - 9.1e-46 155.2 2.5 9.1e-46 155.2 1.7 3.2 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 ETS82771.1 - 6.6e-30 102.8 0.3 5.4e-29 99.9 0.1 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 ETS82771.1 - 3.6e-22 78.6 0.1 6.1e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) E1_DerP2_DerF2 PF02221.10 ETS82772.1 - 1.2e-25 90.3 0.2 1.4e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 ETS82772.1 - 0.0047 16.9 0.1 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 ML-like domain ATP-synt_F PF01990.12 ETS82773.1 - 3.7e-32 110.5 0.1 4.3e-32 110.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 ETS82773.1 - 0.062 12.2 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2418 PF10332.4 ETS82774.1 - 1.3e-28 99.1 2.3 2.2e-28 98.4 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF4375 PF14300.1 ETS82775.1 - 0.3 11.0 0.8 0.62 10.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Aconitase PF00330.15 ETS82776.1 - 3.9e-179 596.0 0.1 5.1e-179 595.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS82776.1 - 1.2e-43 148.3 0.0 2.1e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain G-patch PF01585.18 ETS82776.1 - 0.88 9.4 3.1 19 5.1 0.1 2.8 2 0 0 2 2 2 0 G-patch domain Epimerase PF01370.16 ETS82777.1 - 1e-09 38.1 0.2 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS82777.1 - 1.9e-06 26.9 0.4 1.5e-05 24.0 0.1 2.4 3 0 0 3 3 3 1 Male sterility protein NAD_binding_10 PF13460.1 ETS82777.1 - 9e-06 25.8 0.2 2.2e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 ETS82777.1 - 0.00082 18.7 0.3 0.0013 18.0 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 ETS82777.1 - 0.0011 17.7 0.0 0.0084 14.8 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 ETS82777.1 - 0.0054 15.7 0.1 0.0078 15.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS82777.1 - 0.036 14.3 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS82777.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 ETS82778.1 - 4.9e-09 35.3 16.1 4.9e-09 35.3 11.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS82778.1 - 0.12 10.7 13.2 0.16 10.3 8.6 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein DUF4131 PF13567.1 ETS82778.1 - 1 8.7 6.9 0.54 9.6 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 ETS82779.1 - 5.2e-36 124.0 25.9 7.8e-36 123.5 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS82779.1 - 3.2e-15 55.3 12.3 4e-15 55.0 8.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS82779.1 - 2.3e-13 49.5 11.5 2.3e-13 49.5 8.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_3 PF05106.7 ETS82779.1 - 0.0079 16.1 0.2 0.028 14.4 0.1 2.0 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) EthD PF07110.6 ETS82780.1 - 4.4e-11 43.5 0.1 6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain NmrA PF05368.8 ETS82781.1 - 2.3e-17 63.0 0.0 2.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS82781.1 - 1.7e-15 57.5 0.7 5.7e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS82781.1 - 9.9e-06 24.4 0.1 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETS82781.1 - 2.3e-05 24.3 0.2 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 ETS82781.1 - 6e-05 22.5 0.1 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 ETS82781.1 - 7.1e-05 22.7 0.1 0.0033 17.4 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 ETS82781.1 - 0.00022 21.5 0.5 0.00092 19.5 0.4 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 ETS82781.1 - 0.001 19.3 0.5 0.004 17.4 0.1 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS82781.1 - 0.0019 18.3 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 ETS82781.1 - 0.0068 16.3 0.9 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_7 PF13241.1 ETS82781.1 - 0.013 15.7 0.1 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 ETS82781.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Polysacc_synt_2 PF02719.10 ETS82781.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 ETS82781.1 - 0.031 13.9 0.1 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.16 ETS82781.1 - 0.048 13.2 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DnaJ PF00226.26 ETS82782.1 - 3.9e-21 74.5 0.7 9.3e-21 73.3 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 ETS82783.1 - 1.2e-13 50.5 0.1 3.2e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tmemb_18A PF09771.4 ETS82783.1 - 0.024 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Ring_hydroxyl_A PF00848.14 ETS82784.1 - 1.6e-31 109.5 2.2 4.4e-31 108.1 1.0 2.1 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS82784.1 - 1.1e-14 53.7 0.0 2.6e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain INCENP_ARK-bind PF03941.10 ETS82785.1 - 2.4e-17 62.5 0.6 2.4e-17 62.5 0.4 2.8 2 1 0 2 2 2 1 Inner centromere protein, ARK binding region VIT1 PF01988.14 ETS82785.1 - 7.5 5.9 10.8 7 6.0 1.3 2.7 2 0 0 2 2 2 0 VIT family NOT2_3_5 PF04153.13 ETS82786.1 - 3.5e-33 114.3 0.8 7.1e-33 113.3 0.6 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 ETS82787.1 - 1.9e-45 154.4 0.2 2.6e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 ETS82787.1 - 0.00048 19.7 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 ETS82787.1 - 0.0034 16.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 ETS82787.1 - 0.0047 15.7 1.3 1.2 7.8 0.0 2.8 3 0 0 3 3 3 2 ArgK protein ATP_bind_1 PF03029.12 ETS82787.1 - 0.0086 15.6 0.9 0.058 12.9 0.6 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 ETS82787.1 - 0.016 15.1 1.0 0.076 12.9 0.7 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 ETS82787.1 - 0.016 15.5 0.1 0.041 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS82787.1 - 0.016 14.9 0.1 0.043 13.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 ETS82787.1 - 0.023 15.0 0.1 0.077 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS82787.1 - 0.024 14.7 0.3 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS82787.1 - 0.024 14.2 0.4 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 ETS82787.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 ETS82787.1 - 0.03 14.8 0.1 0.87 10.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 ETS82787.1 - 0.037 14.0 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 ETS82787.1 - 0.044 13.2 0.1 0.088 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 ETS82787.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 ETS82787.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThuA PF06283.6 ETS82787.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation T2SE PF00437.15 ETS82787.1 - 0.067 12.0 1.2 0.074 11.9 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 ETS82787.1 - 0.12 11.3 1.8 9.1 5.1 0.1 2.5 2 1 1 3 3 3 0 Septin AAA_14 PF13173.1 ETS82787.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mob1_phocein PF03637.12 ETS82788.1 - 2.4e-27 95.7 0.3 4.1e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.3 ETS82789.1 - 4.2e-14 51.9 0.1 6.7e-14 51.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82789.1 - 5e-07 29.5 10.7 8.1e-07 28.8 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC PF03473.12 ETS82790.1 - 4.2e-16 58.6 0.0 8.9e-16 57.5 0.0 1.5 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.11 ETS82790.1 - 7e-12 45.1 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.14 ETS82791.1 - 1e-60 204.7 36.6 1e-58 198.1 25.4 4.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS82791.1 - 5.2e-23 81.2 3.5 5.6e-23 81.1 0.1 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 ETS82791.1 - 7.4e-14 52.3 2.7 8e-06 26.0 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETS82791.1 - 1.8e-11 44.7 18.9 1.8e-11 44.7 13.1 6.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 ETS82791.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 ETS82791.1 - 0.0011 18.2 2.9 0.0011 18.2 2.0 7.0 3 2 4 7 7 7 5 Reovirus sigma C capsid protein DUF4250 PF14056.1 ETS82791.1 - 0.0048 16.5 1.2 17 5.1 0.1 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4250) CUE PF02845.11 ETS82792.1 - 1.4e-11 43.5 0.0 2.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain TALPID3 PF15324.1 ETS82792.1 - 0.013 12.8 1.9 0.017 12.4 1.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Metal_resist PF13801.1 ETS82792.1 - 0.051 13.5 6.3 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 Heavy-metal resistance DUF3329 PF11808.3 ETS82793.1 - 0.1 12.6 0.4 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) DEAD PF00270.24 ETS82794.1 - 1.2e-39 135.5 0.0 1.8e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS82794.1 - 2.7e-20 72.0 0.1 6.9e-20 70.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 ETS82794.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 ETS82794.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GRAM PF02893.15 ETS82796.1 - 9.4e-17 60.2 0.0 1.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Rootletin PF15035.1 ETS82797.1 - 0.0028 17.6 6.4 0.0028 17.6 4.5 3.1 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 ETS82797.1 - 0.022 13.6 0.8 0.064 12.1 0.5 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 ETS82797.1 - 0.025 14.5 5.5 1.9 8.5 0.1 3.0 2 0 0 2 2 2 0 bZIP transcription factor FliD_C PF07195.7 ETS82797.1 - 0.034 13.4 0.4 0.077 12.2 0.3 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3166 PF11365.3 ETS82797.1 - 0.049 14.0 0.9 0.049 14.0 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 ETS82797.1 - 0.22 11.8 6.8 1.4 9.3 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIVA PF05103.8 ETS82797.1 - 1.1 9.3 10.2 3 7.8 0.0 3.3 3 0 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 ETS82797.1 - 1.2 9.4 8.8 0.13 12.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 ETS82797.1 - 1.5 8.3 6.0 4.9 6.7 1.9 2.6 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 ETS82797.1 - 2.4 7.7 5.4 0.8 9.2 0.1 2.5 3 0 0 3 3 3 0 IncA protein DUF4201 PF13870.1 ETS82797.1 - 2.8 7.3 11.9 2.4 7.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF4407 PF14362.1 ETS82797.1 - 8.5 5.2 7.2 0.27 10.1 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC155 PF14662.1 ETS82797.1 - 9.9 5.7 12.9 0.96 9.0 1.2 2.9 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 HIT PF01230.18 ETS82798.1 - 8.7e-24 83.9 0.1 1.4e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETS82798.1 - 3.6e-06 27.2 0.5 4e-05 23.8 0.3 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.24 ETS82799.1 - 6.6e-12 45.7 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS82799.1 - 1.2e-06 28.7 0.0 3.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 ETS82799.1 - 5.9e-05 21.9 0.1 9.4e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 ETS82799.1 - 6.5e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETS82799.1 - 7e-05 21.9 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS82799.1 - 0.00022 20.9 0.0 0.00073 19.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS82799.1 - 0.00024 21.9 0.0 0.0009 20.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS82799.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS82799.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS82799.1 - 0.005 15.9 0.1 0.047 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 ETS82799.1 - 0.006 16.8 0.1 0.017 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 ETS82799.1 - 0.0064 16.4 0.0 0.035 14.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 ETS82799.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 ETS82799.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETS82799.1 - 0.02 14.4 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETS82799.1 - 0.026 14.2 0.0 0.073 12.7 0.0 1.9 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 ETS82799.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 ETS82799.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 ETS82799.1 - 0.1 11.3 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 ETS82799.1 - 0.16 11.6 0.2 0.53 9.9 0.0 2.0 3 0 0 3 3 2 0 Archaeal ATPase MFS_1 PF07690.11 ETS82801.1 - 1.8e-26 92.6 27.7 2.8e-18 65.7 9.0 3.0 2 1 0 3 3 3 3 Major Facilitator Superfamily Ferrochelatase PF00762.14 ETS82802.1 - 6.1e-92 307.9 0.0 7.2e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 ETS82803.1 - 1e-39 136.0 0.0 2e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 ETS82803.1 - 6.5e-30 104.2 0.0 9.5e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 ETS82803.1 - 6.9e-15 54.1 0.5 1.3e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 ETS82803.1 - 1.1e-10 41.8 1.3 1.1e-10 41.8 0.9 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm HeH PF12949.2 ETS82803.1 - 1.3e-05 24.5 0.6 3.3e-05 23.3 0.4 1.7 1 0 0 1 1 1 1 HeH/LEM domain Toprim_3 PF13362.1 ETS82803.1 - 0.0031 17.7 0.0 5.3 7.3 0.0 2.8 2 0 0 2 2 2 2 Toprim domain RNA_POL_M_15KD PF02150.11 ETS82804.1 - 0.038 13.6 1.9 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_6 PF14599.1 ETS82804.1 - 0.32 10.8 2.0 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Zn_clus PF00172.13 ETS82805.1 - 4.4e-07 29.7 9.5 7.8e-07 28.9 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 ETS82806.1 - 7.8e-44 150.6 0.2 9.6e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS82806.1 - 9.8e-09 35.6 5.6 3e-07 30.7 3.9 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS82806.1 - 3.8e-05 23.4 0.0 9.3e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS82806.1 - 0.00085 18.6 8.2 0.0031 16.7 1.0 2.7 1 1 0 1 1 1 1 Amidohydrolase family Acyl_transf_1 PF00698.16 ETS82807.1 - 4.9e-82 275.7 0.0 4.7e-81 272.5 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 ETS82807.1 - 9e-39 131.6 0.0 1.9e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 ETS82807.1 - 3.9e-31 106.6 0.1 1.5e-30 104.7 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 ETS82807.1 - 2e-22 79.3 0.1 7.6e-22 77.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 ETS82807.1 - 0.0035 16.5 1.2 0.026 13.6 0.8 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase PCIF1_WW PF12237.3 ETS82807.1 - 0.019 14.2 0.0 0.053 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain DUF1246 PF06849.7 ETS82807.1 - 0.098 12.4 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1246) MCRS_N PF13325.1 ETS82807.1 - 0.17 11.4 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein ketoacyl-synt PF00109.21 ETS82808.1 - 1e-19 71.0 0.1 2.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 ETS82808.1 - 1.1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 ETS82808.1 - 2.7e-11 43.3 0.2 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 ETS82808.1 - 4.4e-06 26.7 0.0 1.7e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82808.1 - 0.00051 19.7 0.0 0.0019 17.9 0.0 1.9 1 0 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.2 ETS82809.1 - 3.7e-20 72.7 0.0 4.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS82809.1 - 1.1e-06 28.4 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82809.1 - 6.5e-05 22.6 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 ETS82809.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Lactamase_B_3 PF13483.1 ETS82812.1 - 8.9e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 ETS82812.1 - 0.0036 16.8 0.1 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 ETS82813.1 - 1.3e-40 139.2 41.7 1.3e-40 139.2 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS82813.1 - 1.4e-07 30.1 3.3 1.4e-07 30.1 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS82813.1 - 3.6e-07 29.1 30.9 1e-06 27.6 21.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Oxidored_FMN PF00724.15 ETS82814.1 - 2.4e-99 332.5 0.0 2.7e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Prok_Ub PF14454.1 ETS82814.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Peptidase_M43 PF05572.8 ETS82815.1 - 5.1e-19 68.3 1.4 5.9e-19 68.1 0.4 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 ETS82815.1 - 3e-06 27.3 0.4 4.6e-06 26.6 0.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 ETS82815.1 - 4.8e-06 26.2 0.2 7.1e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 ETS82815.1 - 1.8e-05 24.8 3.0 2.7e-05 24.3 2.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 ETS82815.1 - 3.2e-05 24.4 0.4 8.1e-05 23.1 0.3 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 ETS82815.1 - 7.1e-05 22.5 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 ETS82815.1 - 0.0066 15.3 0.7 0.011 14.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase M66 DUF1522 PF07482.6 ETS82815.1 - 0.075 13.1 1.0 0.16 12.1 0.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) Arf PF00025.16 ETS82816.1 - 1.2e-27 96.2 0.0 1.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 ETS82816.1 - 0.0057 16.6 0.1 0.039 13.9 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 ETS82816.1 - 0.02 14.1 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Protocadherin PF08374.6 ETS82817.1 - 8.5e-06 25.5 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Protocadherin Herpes_gE PF02480.11 ETS82817.1 - 0.00014 20.2 0.3 0.00025 19.4 0.2 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Plasmodium_Vir PF05795.6 ETS82817.1 - 0.00016 20.9 0.4 0.00021 20.5 0.3 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein FAM163 PF15069.1 ETS82817.1 - 0.00018 22.1 0.1 0.0013 19.3 0.0 2.3 1 1 2 3 3 3 1 FAM163 family EphA2_TM PF14575.1 ETS82817.1 - 0.00063 20.0 0.2 0.0018 18.5 0.1 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.6 ETS82817.1 - 0.0018 17.9 0.1 0.0057 16.2 0.0 1.8 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein DUF1191 PF06697.7 ETS82817.1 - 0.0037 16.1 0.2 0.0054 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 ETS82817.1 - 0.0042 16.5 0.2 0.0088 15.5 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orthoreo_P10 PF07204.6 ETS82817.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Syndecan PF01034.15 ETS82817.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.1 ETS82817.1 - 0.021 14.9 1.3 0.024 14.7 0.0 1.7 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT Glycophorin_A PF01102.13 ETS82817.1 - 0.024 14.3 0.3 0.048 13.4 0.2 1.5 1 0 0 1 1 1 0 Glycophorin A SKG6 PF08693.5 ETS82817.1 - 0.029 13.6 0.2 0.072 12.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDGLE PF13190.1 ETS82817.1 - 0.045 13.4 0.3 0.089 12.4 0.2 1.5 1 0 0 1 1 1 0 PDGLE domain DUF3481 PF11980.3 ETS82817.1 - 0.052 13.3 0.2 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Hex_IIIa PF02455.11 ETS82817.1 - 0.074 11.7 1.4 0.1 11.2 0.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TMEM51 PF15345.1 ETS82817.1 - 0.14 11.8 2.4 0.4 10.3 1.6 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 DUF1180 PF06679.7 ETS82817.1 - 0.16 11.8 1.8 0.37 10.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BIR PF00653.16 ETS82819.1 - 1.8e-42 143.5 2.0 2.9e-20 72.4 0.9 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 ETS82819.1 - 0.00015 21.0 5.6 0.053 13.2 2.4 4.4 2 0 0 2 2 2 2 AT hook motif GST_N_3 PF13417.1 ETS82820.1 - 1.2e-10 41.4 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS82820.1 - 5.3e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS82820.1 - 0.00031 20.5 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.5 ETS82820.1 - 0.014 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 PAS fold GST_N PF02798.15 ETS82820.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PAS_9 PF13426.1 ETS82820.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 PAS domain GST_C_3 PF14497.1 ETS82820.1 - 0.093 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Clr5 PF14420.1 ETS82823.1 - 5.4e-14 51.8 0.9 5.4e-14 51.8 0.7 2.1 2 0 0 2 2 2 1 Clr5 domain DUF2384 PF09722.5 ETS82823.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) HET PF06985.6 ETS82824.1 - 2.6e-32 111.8 1.7 1.5e-31 109.4 1.1 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.23 ETS82826.1 - 2.9e-71 240.7 6.4 1.2e-70 238.6 1.5 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS82826.1 - 1.5e-10 40.8 19.8 1.5e-10 40.8 13.7 4.9 4 0 0 4 4 4 2 Chitin recognition protein DNase_NucA_NucB PF14040.1 ETS82826.1 - 0.0001 22.4 1.8 0.00072 19.6 0.0 3.0 3 0 0 3 3 3 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 ETS82828.1 - 2.3e-24 84.9 4.1 3.2e-05 23.7 0.0 5.5 5 0 0 5 5 5 5 LysM domain Ferritin_2 PF13668.1 ETS82829.1 - 2.6e-06 27.4 0.1 4.4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_transf_22 PF03901.12 ETS82832.1 - 1.4e-84 284.5 16.2 1.6e-84 284.3 11.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 ETS82833.1 - 2.2e-38 131.1 0.4 2.2e-38 131.1 0.3 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region FAD_binding_3 PF01494.14 ETS82835.1 - 4.9e-12 45.5 0.0 6.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 ETS82835.1 - 0.01 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.14 ETS82836.1 - 0.00017 20.7 0.4 0.00044 19.4 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS82836.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS82836.1 - 0.11 12.2 0.4 0.6 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 ETS82836.1 - 0.19 10.6 2.3 0.6 8.9 0.3 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase NmrA PF05368.8 ETS82837.1 - 3.4e-16 59.2 0.1 4.4e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS82837.1 - 2.8e-10 40.5 0.2 5.3e-10 39.6 0.1 1.5 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS82837.1 - 0.00039 19.9 0.0 0.034 13.5 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Clr5 PF14420.1 ETS82838.1 - 1.6e-15 56.6 2.3 2.2e-15 56.2 0.6 2.1 2 0 0 2 2 2 1 Clr5 domain LtrA PF06772.6 ETS82839.1 - 9.4e-13 47.7 26.1 9.4e-13 47.7 18.1 1.8 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Acyl-CoA_dh_1 PF00441.19 ETS82840.1 - 1.5e-42 145.2 4.2 2.4e-42 144.5 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS82840.1 - 5.2e-28 97.8 0.3 1.6e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS82840.1 - 1.2e-17 63.1 0.0 2.2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS82840.1 - 1.6e-17 63.9 1.1 2.9e-17 63.1 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 ETS82840.1 - 0.0048 16.3 0.2 0.021 14.2 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.20 ETS82841.1 - 6.4e-43 145.0 1.4 7.7e-43 144.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_C13 PF01650.13 ETS82842.1 - 3.2e-41 141.3 0.2 4.1e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 ETS82843.1 - 4e-16 59.1 0.0 1.5e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 ETS82843.1 - 4.5e-10 39.3 1.2 8.4e-10 38.4 0.8 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex IncA PF04156.9 ETS82844.1 - 0.00058 19.4 0.0 0.0008 19.0 0.0 1.1 1 0 0 1 1 1 1 IncA protein Shisa PF13908.1 ETS82844.1 - 0.017 15.2 2.5 0.033 14.3 1.7 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 ETS82844.1 - 0.037 12.2 0.0 0.038 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 ETS82844.1 - 0.057 12.7 0.9 0.12 11.7 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.1 ETS82844.1 - 0.088 11.2 0.0 0.095 11.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Pox_A14 PF05767.7 ETS82844.1 - 0.11 12.5 1.0 0.24 11.4 0.6 1.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 LcrV PF04792.7 ETS82844.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein Myc_target_1 PF15179.1 ETS82844.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 Prominin PF05478.6 ETS82844.1 - 0.17 9.4 0.1 0.19 9.2 0.1 1.1 1 0 0 1 1 1 0 Prominin HAUS6_N PF14661.1 ETS82847.1 - 1.3e-54 185.1 2.1 1.3e-54 185.1 1.4 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Fungal_trans PF04082.13 ETS82848.1 - 2.4e-13 49.5 0.2 4e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS82849.1 - 5.6e-20 71.9 0.4 1.1e-19 70.9 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS82849.1 - 8.5e-13 48.3 0.1 1.7e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82849.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS82849.1 - 2.9e-05 23.1 0.0 8.3e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 ETS82849.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 ETS82849.1 - 0.00019 20.4 0.4 0.0016 17.3 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 ETS82849.1 - 0.0002 20.1 0.3 0.00032 19.4 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS82849.1 - 0.004 17.1 0.5 0.0079 16.2 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS82849.1 - 0.012 14.4 0.1 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain CRCB PF02537.10 ETS82849.1 - 0.09 12.6 1.7 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 CrcB-like protein DapB_N PF01113.15 ETS82849.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 ETS82850.1 - 9.5e-18 64.2 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Peptidase_C24 PF03510.9 ETS82851.1 - 0.035 14.2 0.1 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family DUF485 PF04341.7 ETS82851.1 - 3.3 7.4 8.4 11 5.7 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Pyr_redox_3 PF13738.1 ETS82852.1 - 8.8e-19 68.3 0.0 1.3e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS82852.1 - 1e-12 47.1 0.7 4.4e-11 41.6 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS82852.1 - 7.5e-10 38.2 0.0 9.9e-07 27.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS82852.1 - 2.2e-09 37.5 0.0 0.003 17.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS82852.1 - 4.8e-08 32.9 0.0 6.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS82852.1 - 4.4e-05 23.8 0.7 0.033 14.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 ETS82852.1 - 0.00091 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS82852.1 - 0.0011 19.0 0.0 1.3 9.0 0.0 3.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 ETS82852.1 - 0.0019 18.0 1.4 0.7 9.6 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS82852.1 - 0.0064 15.6 0.3 0.18 10.8 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 ETS82852.1 - 0.018 15.2 0.0 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding DAO PF01266.19 ETS82852.1 - 0.035 12.9 3.5 0.61 8.9 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase IlvN PF07991.7 ETS82852.1 - 0.11 11.8 1.0 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 ETS82852.1 - 0.16 11.4 0.4 2.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 ETS82852.1 - 0.17 11.6 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 ETS82852.1 - 0.2 11.4 0.5 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 ThiF family GIDA PF01134.17 ETS82852.1 - 0.22 10.3 3.7 18 4.0 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 ETS82852.1 - 0.31 9.8 1.5 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Abhydrolase_5 PF12695.2 ETS82853.1 - 1.6e-12 47.4 0.0 2.9e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS82853.1 - 2.5e-11 43.5 0.5 7.1e-10 38.8 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS82853.1 - 8.9e-11 42.0 2.0 1.3e-10 41.5 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS82853.1 - 1.6e-09 37.3 0.0 1.1e-05 24.7 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 ETS82853.1 - 2.1e-06 26.7 0.0 3.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 ETS82853.1 - 0.0014 17.5 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 ETS82853.1 - 0.003 16.1 0.6 0.041 12.3 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 ETS82853.1 - 0.013 14.9 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 ETS82853.1 - 0.018 14.2 4.5 0.42 9.8 2.7 2.7 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_4 PF08386.5 ETS82853.1 - 0.071 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein COesterase PF00135.23 ETS82853.1 - 0.11 11.1 0.0 0.91 8.1 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family MoCF_biosynth PF00994.19 ETS82854.1 - 3.9e-22 78.2 0.0 7.6e-22 77.2 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 ETS82855.1 - 3.4e-09 36.6 0.0 4.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1657 PF07870.6 ETS82855.1 - 0.035 13.7 0.1 0.096 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) ParA PF10609.4 ETS82856.1 - 2.5e-35 120.1 0.0 4.3e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 ETS82856.1 - 3.1e-13 49.5 0.0 4.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 ETS82856.1 - 6.8e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 ETS82856.1 - 0.00029 19.9 0.2 0.0035 16.4 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 ETS82856.1 - 0.0077 15.3 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 ETS82856.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS82856.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VirE PF05272.6 ETS82856.1 - 0.051 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_26 PF13500.1 ETS82856.1 - 0.059 12.9 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS1595 PF12760.2 ETS82856.1 - 0.089 12.6 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain AAA_19 PF13245.1 ETS82856.1 - 0.093 12.4 0.5 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 ETS82856.1 - 0.2 10.5 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Glyco_hydro_28 PF00295.12 ETS82857.1 - 4.8e-09 35.6 1.1 8.6e-09 34.7 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS82857.1 - 0.005 16.6 19.8 1.3 8.7 13.7 3.2 1 1 0 1 1 1 1 Right handed beta helix region Alginate_lyase PF05426.7 ETS82858.1 - 1.5e-13 50.7 1.5 6.3e-13 48.6 1.1 1.8 1 1 0 1 1 1 1 Alginate lyase Hist_deacetyl PF00850.14 ETS82859.1 - 6.3e-60 203.0 0.1 1.2e-59 202.1 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Cutinase PF01083.17 ETS82860.1 - 1e-25 90.5 0.4 1e-25 90.5 0.2 1.8 2 0 0 2 2 2 1 Cutinase DHquinase_I PF01487.10 ETS82861.1 - 8.7e-47 159.6 0.0 1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF372 PF04036.7 ETS82861.1 - 0.12 11.9 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF372) PGI PF00342.14 ETS82862.1 - 3.9e-209 695.0 0.1 4.4e-209 694.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Asparaginase_II PF06089.7 ETS82863.1 - 5.2e-105 350.7 1.0 5.9e-105 350.5 0.7 1.0 1 0 0 1 1 1 1 L-asparaginase II Rep_N PF08724.5 ETS82864.1 - 0.00065 19.2 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Rep protein catalytic domain like HET PF06985.6 ETS82865.1 - 1.8e-28 99.4 0.5 2.8e-28 98.7 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF664 PF04978.7 ETS82865.1 - 0.08 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Cutinase PF01083.17 ETS82866.1 - 7.3e-43 146.3 0.0 8.9e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 ETS82866.1 - 0.0018 18.0 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82866.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS82866.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETS82866.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS82866.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) VirJ PF06057.6 ETS82866.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 ETS82866.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Chlorophyllase2 PF12740.2 ETS82866.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 ETS82866.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) F-box-like PF12937.2 ETS82867.1 - 0.0026 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like Exo5 PF09810.4 ETS82868.1 - 7e-97 324.5 0.0 1.2e-96 323.7 0.0 1.4 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PAS_9 PF13426.1 ETS82869.1 - 6.7e-20 71.4 0.0 8.5e-16 58.2 0.0 2.9 3 0 0 3 3 3 2 PAS domain RGS PF00615.14 ETS82869.1 - 8.2e-08 32.3 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.5 ETS82869.1 - 4.4e-05 23.4 0.0 0.0099 15.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 ETS82869.1 - 0.027 14.2 0.0 0.17 11.7 0.0 2.3 3 0 0 3 3 3 0 PAS fold PAS_3 PF08447.6 ETS82869.1 - 0.058 13.5 0.0 0.19 11.8 0.0 1.9 2 1 0 2 2 2 0 PAS fold Glyco_transf_90 PF05686.7 ETS82870.1 - 1.4e-13 50.2 0.0 3.2e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Esterase_phd PF10503.4 ETS82871.1 - 2.2e-21 76.1 0.1 3.3e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 ETS82871.1 - 1.4e-06 28.3 0.2 3.4e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS82871.1 - 1.1e-05 24.7 0.3 1.8e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS82871.1 - 1.2e-05 25.0 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82871.1 - 1.5e-05 24.6 0.5 2.5e-05 23.9 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 ETS82871.1 - 0.025 14.1 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 ETS82871.1 - 0.093 12.1 2.7 0.18 11.2 1.9 1.6 1 1 0 1 1 1 0 Putative esterase ABC2_membrane PF01061.19 ETS82872.1 - 7.9e-79 263.6 45.5 7.5e-41 139.6 15.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 ETS82872.1 - 6.2e-44 149.6 0.1 1.9e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS82872.1 - 3.3e-22 78.1 0.2 9.7e-19 66.9 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter SMC_N PF02463.14 ETS82872.1 - 1e-06 28.1 0.0 0.11 11.7 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 ETS82872.1 - 6.6e-06 25.3 36.8 6.7e-05 22.0 14.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 ETS82872.1 - 3.4e-05 23.0 0.3 0.00022 20.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETS82872.1 - 8.2e-05 22.4 0.0 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 ETS82872.1 - 9.9e-05 22.3 0.1 0.042 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 ETS82872.1 - 0.00026 20.4 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS82872.1 - 0.00062 19.9 0.1 0.083 13.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETS82872.1 - 0.00065 19.3 0.3 0.031 13.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 ETS82872.1 - 0.0014 18.6 0.0 0.0065 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETS82872.1 - 0.0015 17.9 1.0 0.02 14.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 ETS82872.1 - 0.0063 15.9 0.1 0.34 10.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2931 PF11153.3 ETS82872.1 - 0.0064 15.8 0.1 0.037 13.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2931) AAA_19 PF13245.1 ETS82872.1 - 0.007 16.0 0.1 5.5 6.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain PduV-EutP PF10662.4 ETS82872.1 - 0.011 15.2 0.1 0.47 9.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETS82872.1 - 0.014 16.2 0.2 0.21 12.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 ETS82872.1 - 0.014 15.0 0.3 0.56 9.8 0.1 2.7 3 0 0 3 3 2 0 NACHT domain AAA_18 PF13238.1 ETS82872.1 - 0.016 15.5 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS82872.1 - 0.036 13.9 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 ETS82872.1 - 0.038 14.1 0.0 8.3 6.6 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETS82872.1 - 0.04 13.4 0.1 0.63 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS82872.1 - 0.05 13.5 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 ETS82872.1 - 0.069 13.6 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 ETS82872.1 - 0.18 10.6 0.4 3.5 6.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fungal_trans PF04082.13 ETS82873.1 - 1.1e-19 70.3 0.5 2.6e-19 69.0 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82873.1 - 2.3e-08 33.7 12.9 4.5e-08 32.8 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_6 PF14579.1 ETS82873.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ank_2 PF12796.2 ETS82874.1 - 1.1e-100 330.1 0.9 1.2e-15 57.6 0.0 12.7 7 3 5 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82874.1 - 1.9e-77 251.4 22.8 6.4e-07 28.8 0.0 21.3 22 0 0 22 22 22 14 Ankyrin repeat Ank_4 PF13637.1 ETS82874.1 - 1.1e-63 210.4 15.2 1.8e-09 37.8 0.0 16.6 12 4 3 16 16 16 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS82874.1 - 3.6e-57 189.0 17.6 2.3e-11 43.5 0.2 16.6 12 4 5 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82874.1 - 6.7e-55 177.5 7.3 0.00044 20.2 0.0 21.4 22 0 0 22 22 22 11 Ankyrin repeat Arylsulfotran_2 PF14269.1 ETS82875.1 - 7.5e-67 225.5 9.6 1e-66 225.1 6.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 ETS82875.1 - 4.6e-13 48.5 9.0 2.1e-12 46.2 6.2 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF2236 PF09995.4 ETS82877.1 - 1.2e-49 168.7 3.3 1.5e-49 168.5 2.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FWWh PF14922.1 ETS82877.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Polysacc_lyase PF14099.1 ETS82878.1 - 8.6e-21 74.6 0.1 1.1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.1 ETS82878.1 - 0.091 12.9 5.5 0.13 12.4 3.0 1.8 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TauD PF02668.11 ETS82879.1 - 3.2e-49 167.9 0.5 4.3e-49 167.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1993 PF09351.5 ETS82880.1 - 1.6e-44 151.6 0.1 1.8e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) AF0941-like PF14591.1 ETS82880.1 - 0.061 13.3 0.3 0.097 12.7 0.1 1.4 1 1 0 1 1 1 0 AF0941-like Ras PF00071.17 ETS82881.1 - 7e-59 197.8 0.2 8.2e-59 197.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS82881.1 - 8.3e-18 65.0 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS82881.1 - 1.7e-07 30.6 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS82881.1 - 6.8e-06 25.6 0.1 3.4e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS82881.1 - 0.0028 17.6 0.0 0.0042 17.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS82881.1 - 0.006 15.8 0.0 0.02 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 ETS82881.1 - 0.047 12.8 0.2 0.1 11.7 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 ETS82881.1 - 0.094 12.2 1.7 1.2 8.5 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 ETS82881.1 - 0.18 11.1 0.3 0.68 9.3 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein HC2 PF07382.6 ETS82882.1 - 5.5e-06 26.3 27.2 5.5e-06 26.3 18.8 1.7 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 CENP-B_dimeris PF09026.5 ETS82882.1 - 0.0032 17.6 4.2 0.0032 17.6 2.9 3.2 3 0 0 3 3 3 1 Centromere protein B dimerisation domain DUF913 PF06025.7 ETS82882.1 - 9.6 4.8 7.5 16 4.0 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Peptidase_M20 PF01546.23 ETS82883.1 - 7.3e-28 97.3 4.4 1.3e-27 96.5 3.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS82883.1 - 3.5e-20 71.8 0.1 8.1e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS82883.1 - 0.0034 17.1 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Choline_kin_N PF04428.9 ETS82883.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus APC_CDC26 PF10471.4 ETS82883.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Anp1 PF03452.9 ETS82884.1 - 4.4e-25 88.3 0.0 6.1e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Anp1 Acetyltransf_1 PF00583.19 ETS82885.1 - 4.7e-08 32.9 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS82885.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS82885.1 - 0.00031 20.8 0.0 0.00072 19.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS82885.1 - 0.026 14.6 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF605 PF04652.11 ETS82886.1 - 8 5.7 15.7 12 5.1 10.9 1.3 1 0 0 1 1 1 0 Vta1 like His_Phos_2 PF00328.17 ETS82887.1 - 7.6e-41 140.5 0.0 1.4e-40 139.6 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S9 PF00326.16 ETS82889.1 - 1.8e-20 73.0 0.0 2.9e-20 72.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS82889.1 - 1.6e-10 40.9 0.1 2.1e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS82889.1 - 1.9e-10 40.6 0.2 1.5e-09 37.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS82889.1 - 2.9e-06 27.3 1.1 5.4e-05 23.1 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS82889.1 - 0.00069 18.9 0.0 0.0024 17.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.4 ETS82889.1 - 0.0028 16.5 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) LIP PF03583.9 ETS82889.1 - 0.072 12.2 0.6 5.2 6.1 0.0 2.3 1 1 1 2 2 2 0 Secretory lipase DUF4149 PF13664.1 ETS82891.1 - 0.51 10.4 3.7 0.85 9.7 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) p450 PF00067.17 ETS82892.1 - 2.7e-49 167.9 0.0 3.6e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.19 ETS82893.1 - 8.9e-43 145.2 27.8 9.1e-22 77.1 4.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PGA2 PF07543.7 ETS82893.1 - 1.4 8.6 4.3 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 ORC6 PF05460.8 ETS82893.1 - 1.7 7.6 6.2 1.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF1510 PF07423.6 ETS82893.1 - 6.3 6.1 7.6 0.29 10.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3608 PF12257.3 ETS82894.1 - 2.7e-72 243.0 0.1 6.4e-72 241.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 ETS82894.1 - 2.3e-28 97.7 0.1 5e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) adh_short PF00106.20 ETS82895.1 - 7.5e-17 61.7 0.3 1.2e-16 61.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS82895.1 - 1.2e-07 31.6 0.2 3.6e-07 30.0 0.0 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 ETS82895.1 - 0.001 18.0 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS82895.1 - 0.0035 16.8 0.2 0.0061 16.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MoCF_biosynth PF00994.19 ETS82895.1 - 0.082 12.3 0.1 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Probable molybdopterin binding domain Cation_efflux PF01545.16 ETS82896.1 - 2e-67 227.2 1.8 2.7e-67 226.8 1.2 1.2 1 0 0 1 1 1 1 Cation efflux family FNIP_N PF14636.1 ETS82897.1 - 2.2e-27 96.0 0.4 2.2e-27 96.0 0.3 4.4 6 0 0 6 6 6 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 ETS82897.1 - 0.12 11.9 0.1 0.56 9.7 0.0 2.0 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain Tyrosinase PF00264.15 ETS82898.1 - 3.2e-33 115.7 6.0 4.5e-33 115.2 4.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase AAA PF00004.24 ETS82900.1 - 4.9e-19 68.8 0.0 5.7e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS82900.1 - 0.00021 20.9 0.3 0.00076 19.1 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS82900.1 - 0.0018 18.4 1.3 0.065 13.3 0.1 3.0 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS82900.1 - 0.011 15.7 0.1 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 ETS82900.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS82900.1 - 0.077 13.8 0.1 0.24 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS82900.1 - 0.079 12.6 0.2 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETS82900.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Glyco_hydro_61 PF03443.9 ETS82901.1 - 4e-60 203.3 0.1 4.6e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans_2 PF11951.3 ETS82902.1 - 5.8e-27 94.2 0.0 4.2e-26 91.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS82902.1 - 1.4e-07 31.3 2.7 2.3e-07 30.6 1.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.19 ETS82903.1 - 1.8e-38 132.2 0.0 2.1e-37 128.7 0.0 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 ETS82903.1 - 0.0011 19.5 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 ETS82904.1 - 9.6e-35 120.0 29.5 2.5e-18 65.8 6.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS82904.1 - 1.6e-23 83.0 44.3 3.7e-13 48.9 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2231 PF09990.4 ETS82904.1 - 0.11 12.8 6.5 0.52 10.6 4.5 2.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Mlo PF03094.10 ETS82904.1 - 0.13 10.3 0.1 0.21 9.6 0.0 1.2 1 0 0 1 1 1 0 Mlo family DUF3328 PF11807.3 ETS82905.1 - 5.3e-05 22.9 2.2 0.00024 20.8 1.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MAD PF05557.8 ETS82906.1 - 5.6e-56 190.0 67.0 6.9e-56 189.7 46.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF1027 PF06265.6 ETS82906.1 - 0.093 12.6 0.0 0.45 10.4 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Mmp37 PF09139.6 ETS82907.1 - 5.5e-135 449.6 0.0 8e-135 449.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 p450 PF00067.17 ETS82908.1 - 1.6e-42 145.6 0.0 3.3e-42 144.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 LANC_like PF05147.8 ETS82909.1 - 1.3e-28 99.6 0.0 4.4e-28 97.8 0.0 1.7 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Methyltransf_12 PF08242.7 ETS82910.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82910.1 - 2.2e-10 41.1 0.1 3.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS82910.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS82910.1 - 2.2e-09 37.2 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS82910.1 - 3.4e-09 37.0 0.0 5.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS82910.1 - 6.1e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS82910.1 - 3.8e-08 33.6 0.0 5.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS82910.1 - 2.3e-07 30.1 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 ETS82910.1 - 1e-05 24.9 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 ETS82910.1 - 9.5e-05 21.8 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 ETS82910.1 - 0.00073 18.7 0.0 0.00098 18.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 ETS82910.1 - 0.00074 18.7 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.5 ETS82910.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Cons_hypoth95 PF03602.10 ETS82910.1 - 0.026 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_6 PF12697.2 ETS82911.1 - 1.7e-35 122.9 0.0 2e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS82911.1 - 6.9e-22 78.1 0.0 1.2e-21 77.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS82911.1 - 1.7e-15 57.0 0.0 2.6e-15 56.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS82911.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 ETS82911.1 - 0.0019 17.7 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein DUF1651 PF07864.6 ETS82911.1 - 0.0046 17.0 2.5 0.15 12.1 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1651) DUF2974 PF11187.3 ETS82911.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 ETS82911.1 - 0.011 15.0 0.1 0.33 10.1 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF900 PF05990.7 ETS82911.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 ETS82911.1 - 0.02 14.4 0.0 0.16 11.5 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 ETS82911.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Ran_BP1 PF00638.13 ETS82912.1 - 2.4e-14 53.4 0.0 2.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain p450 PF00067.17 ETS82913.1 - 1.1e-36 126.3 0.2 8.1e-22 77.3 0.1 2.7 2 1 0 2 2 2 2 Cytochrome P450 Cupin_2 PF07883.6 ETS82914.1 - 4.5e-08 32.4 0.0 8.9e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS82914.1 - 0.00045 19.6 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Cupin PI-PLC-X PF00388.14 ETS82915.1 - 7e-49 164.9 0.0 1.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 ETS82915.1 - 7.9e-31 106.4 0.0 1.6e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 ETS82915.1 - 0.059 13.2 0.9 0.3 10.9 0.1 2.4 2 1 0 2 2 2 0 C2 domain Ank_2 PF12796.2 ETS82916.1 - 2.8e-63 210.2 25.9 3.7e-07 30.4 0.0 15.1 7 5 6 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 ETS82916.1 - 8.3e-28 94.7 28.0 0.0041 16.8 0.0 19.3 20 0 0 20 20 20 7 Ankyrin repeat Ank_4 PF13637.1 ETS82916.1 - 2.9e-19 69.0 19.9 0.021 15.3 0.0 15.8 17 3 2 19 19 19 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS82916.1 - 5e-17 60.2 12.0 0.21 11.9 0.0 18.3 21 1 1 22 22 22 2 Ankyrin repeat Ank_5 PF13857.1 ETS82916.1 - 3.8e-15 55.5 19.4 0.00019 21.5 0.0 11.7 11 2 2 13 13 13 5 Ankyrin repeats (many copies) Epimerase PF01370.16 ETS82917.1 - 2e-45 155.0 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 ETS82917.1 - 1.2e-25 89.1 0.1 2.3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 ETS82917.1 - 8e-18 64.1 0.0 2.8e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS82917.1 - 9.2e-15 54.3 0.0 8.2e-13 47.9 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETS82917.1 - 1.8e-13 50.0 0.0 2.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS82917.1 - 1.1e-12 48.1 0.0 1.8e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETS82917.1 - 6.6e-10 38.3 0.0 2.2e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 ETS82917.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS82917.1 - 1.8e-08 34.5 0.0 3.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_18 PF12847.2 ETS82917.1 - 0.0035 17.9 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 ETS82917.1 - 0.0095 15.3 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 ETS82917.1 - 0.02 14.1 0.0 0.088 12.0 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Methyltransf_31 PF13847.1 ETS82917.1 - 0.025 14.1 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Phage_lysozyme PF00959.14 ETS82917.1 - 0.12 12.6 0.1 0.92 9.8 0.0 2.2 2 0 0 2 2 2 0 Phage lysozyme Sad1_UNC PF07738.8 ETS82919.1 - 1.1e-05 25.1 0.0 0.0049 16.6 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DEAD PF00270.24 ETS82920.1 - 4.1e-42 143.5 0.0 8.8e-42 142.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 ETS82920.1 - 1.6e-22 78.7 0.0 4.2e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 ETS82920.1 - 1.4e-21 76.1 0.0 3.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAPS_reduct PF01507.14 ETS82921.1 - 8e-33 113.6 0.0 4e-29 101.6 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family BRCT PF00533.21 ETS82922.1 - 0.0024 17.9 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nucleoplasmin PF03066.10 ETS82922.1 - 0.086 12.3 16.1 0.12 11.8 4.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 ETS82922.1 - 0.13 12.0 10.7 0.21 11.4 1.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Prothymosin PF03247.9 ETS82922.1 - 0.36 10.9 23.8 0.8 9.8 5.9 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family PBP1_TM PF14812.1 ETS82922.1 - 0.37 11.1 26.4 0.17 12.2 7.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FLO_LFY PF01698.11 ETS82922.1 - 1 8.1 7.3 0.13 11.0 0.6 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein Tim54 PF11711.3 ETS82922.1 - 1.1 7.8 11.4 0.036 12.6 1.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4611 PF15387.1 ETS82922.1 - 1.6 8.9 17.3 1.3 9.2 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TLP-20 PF06088.6 ETS82922.1 - 2.8 7.5 8.5 1.4 8.5 1.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Rhabdo_ncap PF00945.13 ETS82922.1 - 2.9 6.3 6.6 1.2 7.6 1.2 2.1 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein CENP-B_dimeris PF09026.5 ETS82922.1 - 5.9 7.2 15.6 1.3 9.2 5.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 ETS82922.1 - 6.3 4.5 10.4 0.06 11.2 1.9 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DLH PF01738.13 ETS82923.1 - 5e-17 61.9 0.1 6.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS82923.1 - 1.7e-06 27.8 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS82923.1 - 2.4e-05 24.3 2.0 0.0018 18.2 0.5 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS82923.1 - 0.045 12.9 0.0 0.38 9.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_M1 PF01433.15 ETS82924.1 - 2.3e-100 336.4 0.0 4e-100 335.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 ETS82924.1 - 3.5e-43 148.0 0.3 5.3e-43 147.4 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 ETS82924.1 - 1e-17 64.3 0.1 1.9e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily BCS1_N PF08740.6 ETS82925.1 - 5.4e-31 107.6 1.0 8.4e-31 107.0 0.2 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 ETS82925.1 - 3.2e-22 79.1 0.0 5.6e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS82925.1 - 7e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS82925.1 - 0.00018 22.2 0.0 0.00052 20.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 ETS82925.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 ETS82925.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 ETS82925.1 - 0.0014 18.7 0.0 0.0044 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 ETS82925.1 - 0.0062 16.2 0.0 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) YL1_C PF08265.6 ETS82925.1 - 0.0069 15.9 0.7 0.018 14.5 0.5 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA_25 PF13481.1 ETS82925.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS82925.1 - 0.029 14.4 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS82925.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 ETS82925.1 - 0.049 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETS82925.1 - 0.056 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 ETS82925.1 - 0.11 12.0 0.2 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS82925.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CVNH PF08881.5 ETS82926.1 - 1.2e-30 105.7 0.9 1.6e-30 105.3 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.10 ETS82926.1 - 2.7e-05 23.7 12.0 6.1e-05 22.5 8.3 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 ETS82926.1 - 0.0021 17.6 0.4 0.0041 16.7 0.3 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 ETS82926.1 - 0.012 15.2 7.0 0.021 14.4 4.8 1.4 1 0 0 1 1 1 0 Glycine zipper DUF533 PF04391.7 ETS82926.1 - 0.036 13.4 0.4 0.058 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Pex14_N PF04695.8 ETS82926.1 - 0.09 12.8 0.3 0.09 12.8 0.2 3.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dehydrin PF00257.14 ETS82926.1 - 0.21 11.8 4.9 0.25 11.6 2.9 1.5 1 1 0 1 1 1 0 Dehydrin Gly-zipper_YMGG PF13441.1 ETS82926.1 - 0.39 10.2 11.5 0.9 9.0 8.0 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper SR-25 PF10500.4 ETS82926.1 - 0.68 9.3 7.7 1.1 8.7 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC2_membrane PF01061.19 ETS82928.1 - 1e-84 282.9 51.7 1.1e-47 161.9 12.1 2.9 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 ETS82928.1 - 1.7e-38 130.3 0.7 2.9e-30 103.9 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 ETS82928.1 - 5.4e-32 110.9 0.0 6.9e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 ETS82928.1 - 8.9e-18 64.4 33.4 4.3e-09 35.8 11.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 ETS82928.1 - 1.1e-08 35.0 0.0 3.9e-08 33.2 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS82928.1 - 2.9e-08 33.3 0.1 0.00091 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 ETS82928.1 - 8.8e-07 28.5 0.1 0.00032 20.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 ETS82928.1 - 5.3e-06 26.6 0.0 0.13 12.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS82928.1 - 1e-05 25.6 0.4 0.0053 16.7 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS82928.1 - 2.4e-05 25.1 0.0 0.016 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS82928.1 - 3.8e-05 22.9 0.0 7.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS82928.1 - 0.00018 21.6 0.1 0.13 12.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS82928.1 - 0.00039 19.8 0.0 0.026 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 ETS82928.1 - 0.00049 19.7 0.5 0.1 12.2 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 ETS82928.1 - 0.00088 18.9 0.1 0.2 11.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 ETS82928.1 - 0.0017 17.8 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 ETS82928.1 - 0.0018 18.0 0.3 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 ETS82928.1 - 0.0026 17.6 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS82928.1 - 0.0084 16.4 0.1 0.22 11.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 ETS82928.1 - 0.0095 14.8 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 ETS82928.1 - 0.011 16.1 2.2 1.2 9.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS82928.1 - 0.016 15.2 0.1 0.016 15.2 0.1 2.8 4 0 0 4 4 2 0 AAA domain AAA_10 PF12846.2 ETS82928.1 - 0.017 14.5 0.7 3.3 7.0 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.24 ETS82928.1 - 0.03 14.5 0.1 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETS82928.1 - 0.041 13.8 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETS82928.1 - 0.062 13.0 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 ETS82928.1 - 0.083 13.0 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 ETS82928.1 - 0.12 11.4 0.4 2.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Septin KaiC PF06745.8 ETS82928.1 - 0.17 10.9 0.0 7.3 5.6 0.0 2.3 2 0 0 2 2 2 0 KaiC Miro PF08477.8 ETS82928.1 - 0.18 12.3 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 ETS82928.1 - 0.33 10.4 1.2 1.7 8.1 0.1 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3275 PF11679.3 ETS82929.1 - 3.9 7.0 5.8 6.4 6.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF2781 PF10914.3 ETS82931.1 - 4.3e-31 107.7 6.9 5e-31 107.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Mg_trans_NIPA PF05653.9 ETS82933.1 - 8.9e-89 297.3 26.9 1.2e-88 296.9 18.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 ETS82933.1 - 1.7e-07 31.4 4.5 1.7e-07 31.4 3.1 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 ETS82933.1 - 2.5e-05 24.3 6.2 2.5e-05 24.3 4.3 2.8 3 0 0 3 3 3 1 EamA-like transporter family Clr5 PF14420.1 ETS82935.1 - 1e-17 63.7 0.6 2.3e-17 62.6 0.4 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_11 PF13414.1 ETS82936.1 - 1e-20 73.1 6.5 1.9e-16 59.4 0.1 2.8 2 1 1 3 3 3 2 TPR repeat U-box PF04564.10 ETS82936.1 - 2.9e-20 71.9 0.0 5.8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.23 ETS82936.1 - 9.2e-11 40.8 3.6 0.0038 16.7 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS82936.1 - 2.9e-08 33.5 3.7 6.1e-05 22.8 2.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS82936.1 - 2.9e-08 33.0 2.9 0.00075 19.2 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS82936.1 - 7.4e-07 28.8 5.3 0.0056 16.7 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS82936.1 - 1.1e-06 28.9 2.5 0.014 15.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS82936.1 - 5.9e-06 26.7 3.7 0.011 16.3 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS82936.1 - 6.7e-06 26.2 1.3 0.078 13.6 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS82936.1 - 5.3e-05 23.2 1.9 0.0001 22.3 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 LUC7 PF03194.10 ETS82936.1 - 0.00047 19.7 1.9 0.00061 19.3 1.3 1.2 1 0 0 1 1 1 1 LUC7 N_terminus TPR_4 PF07721.9 ETS82936.1 - 0.0016 18.6 0.1 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS82936.1 - 0.0016 18.0 0.7 0.041 13.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS82936.1 - 0.032 14.1 0.2 5.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS82936.1 - 0.04 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat zf-Nse PF11789.3 ETS82936.1 - 0.042 13.3 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_8 PF13181.1 ETS82936.1 - 0.21 11.4 1.9 0.32 10.8 0.1 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS82936.1 - 0.27 11.7 0.3 0.27 11.7 0.2 2.8 4 0 0 4 4 2 0 Tetratricopeptide repeat Transferase PF02458.10 ETS82937.1 - 1.8e-19 69.5 0.0 3.2e-18 65.3 0.0 2.5 2 1 0 2 2 2 1 Transferase family Lipoxygenase PF00305.14 ETS82938.1 - 8.9e-32 109.9 0.0 1.2e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Pkinase PF00069.20 ETS82939.1 - 1.1e-10 41.1 0.0 2.1e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 ETS82939.1 - 0.0002 21.1 3.7 0.0098 15.6 0.5 3.0 1 1 2 3 3 3 2 Phosphotransferase enzyme family PRANC PF09372.5 ETS82940.1 - 0.21 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 PRANC domain HTH_Tnp_Tc5 PF03221.11 ETS82942.1 - 2.1e-21 75.5 5.2 4e-05 23.3 0.0 6.0 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 ETS82942.1 - 2.5e-13 49.5 0.4 2.5e-13 49.5 0.3 3.5 3 1 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 ETS82942.1 - 2.9e-05 23.5 0.3 9.2e-05 21.9 0.2 1.9 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 ETS82942.1 - 0.014 15.6 4.2 0.014 15.6 2.9 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS82942.1 - 0.035 14.4 19.2 0.032 14.5 2.6 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type PAN_1 PF00024.21 ETS82943.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.1 ETS82943.1 - 0.37 10.5 4.6 25 4.6 3.2 2.7 1 1 0 1 1 1 0 PAN domain Elicitin PF00964.12 ETS82943.1 - 0.62 10.0 6.4 0.58 10.1 2.6 2.3 1 1 1 2 2 2 0 Elicitin HEAT_2 PF13646.1 ETS82944.1 - 2.7e-28 98.0 18.2 1.9e-07 31.2 0.0 6.5 4 2 2 7 7 7 6 HEAT repeats HEAT PF02985.17 ETS82944.1 - 2.2e-10 39.7 11.0 0.29 11.3 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.2 ETS82944.1 - 8e-07 29.0 3.3 7.2 6.4 0.0 5.8 6 1 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETS82944.1 - 1.4e-06 28.5 19.2 0.44 11.1 0.0 8.6 5 4 6 11 11 11 3 HEAT-like repeat Cohesin_HEAT PF12765.2 ETS82944.1 - 2.2e-06 27.5 10.3 0.36 10.8 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 ETS82944.1 - 2.3e-05 24.2 3.6 0.59 10.0 0.0 5.4 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 ETS82944.1 - 0.00089 17.6 8.9 0.23 9.7 1.2 4.3 3 2 0 3 3 3 2 Adaptin N terminal region RB_B PF01857.15 ETS82944.1 - 0.0014 18.1 0.0 0.21 11.0 0.0 3.4 2 1 2 4 4 4 1 Retinoblastoma-associated protein B domain DUF3554 PF12074.3 ETS82944.1 - 0.014 14.8 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) DUF507 PF04368.8 ETS82944.1 - 0.014 15.0 4.6 0.096 12.3 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF507) Arm PF00514.18 ETS82944.1 - 0.25 11.2 3.9 25 4.8 0.1 5.1 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat NACHT PF05729.7 ETS82945.1 - 8.3e-15 54.8 0.0 1.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS82945.1 - 3.9e-05 23.7 0.0 0.00019 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 ETS82945.1 - 0.00097 19.9 0.2 0.0028 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS82945.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETS82945.1 - 0.0028 16.5 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 ETS82945.1 - 0.003 17.4 0.0 0.008 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 ETS82945.1 - 0.0037 16.8 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein NTPase_1 PF03266.10 ETS82945.1 - 0.012 15.3 0.0 0.06 13.0 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 ETS82945.1 - 0.023 15.0 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS82945.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 ETS82945.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 ETS82945.1 - 0.056 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 ETS82945.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.4 ETS82945.1 - 0.073 11.9 0.0 0.59 9.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NT5C PF06941.7 ETS82945.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Lactamase_B PF00753.22 ETS82946.1 - 4.2e-09 36.3 4.2 1.5e-08 34.5 2.9 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS82946.1 - 0.00014 21.4 0.2 0.00021 20.8 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ubie_methyltran PF01209.13 ETS82947.1 - 1.4e-10 40.6 0.0 2.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 ETS82947.1 - 1.7e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS82947.1 - 2.4e-09 37.5 0.0 5.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS82947.1 - 2.9e-07 30.3 0.0 7.1e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS82947.1 - 2.2e-06 27.9 0.0 1.2e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS82947.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS82947.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 ETS82947.1 - 0.046 13.7 0.0 0.23 11.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CAP_N PF01213.14 ETS82948.1 - 0.049 12.9 0.2 0.073 12.3 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nucleoporin_C PF03177.9 ETS82949.1 - 4.7e-120 401.8 10.9 6.4e-120 401.4 7.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 ETS82949.1 - 4.8e-82 275.9 0.1 6.4e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 ETS82950.1 - 4e-23 82.1 0.0 5.3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82950.1 - 3.5e-11 43.3 0.0 4.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82950.1 - 5.4e-06 26.1 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS82950.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS82950.1 - 0.0028 16.5 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS82950.1 - 0.029 14.4 0.3 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Erg28 PF03694.8 ETS82951.1 - 3.7e-38 129.9 0.4 4.8e-38 129.5 0.3 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 ETS82952.1 - 9.8e-68 227.8 0.0 5.2e-66 222.1 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 ETS82952.1 - 5.4e-56 188.7 0.1 9.6e-56 187.8 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 ETS82952.1 - 4.8e-05 23.8 0.0 0.00044 20.7 0.0 2.2 2 1 0 2 2 2 1 HIT domain SWIRM PF04433.12 ETS82954.1 - 8.8e-13 48.2 0.0 3.6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 ETS82954.1 - 1.5e-10 40.4 5.7 3.6e-10 39.2 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 ETS82954.1 - 2.4e-07 30.6 0.0 6.9e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain O-FucT PF10250.4 ETS82955.1 - 1.4e-13 50.7 0.0 9.4e-11 41.4 0.0 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Rhodanese PF00581.15 ETS82956.1 - 1.5e-14 54.2 0.0 2.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF3722 PF12519.3 ETS82956.1 - 0.042 13.0 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) TraB PF01963.12 ETS82956.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 TraB family NUC153 PF08159.7 ETS82960.1 - 1.6e-12 46.7 1.0 1.6e-12 46.7 0.7 4.3 4 1 0 4 4 4 2 NUC153 domain PLDc_2 PF13091.1 ETS82961.1 - 4.8e-15 55.4 0.0 1.6e-06 27.9 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 ETS82961.1 - 8.5e-11 41.2 2.1 0.00028 20.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif F_bP_aldolase PF01116.15 ETS82961.1 - 0.16 11.0 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Ribonuclease_T2 PF00445.13 ETS82962.1 - 3.2e-28 98.6 0.0 7.4e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.11 ETS82963.1 - 1.1e-57 195.0 1.1 1.8e-57 194.3 0.7 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.4 ETS82963.1 - 0.16 10.5 0.3 0.22 10.0 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAT1 PF09770.4 ETS82963.1 - 2.2 6.4 44.9 3.3 5.8 31.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MatE PF01554.13 ETS82965.1 - 1.6e-52 177.3 29.3 1.5e-27 96.2 6.5 2.3 2 0 0 2 2 2 2 MatE DUF202 PF02656.10 ETS82966.1 - 2.4e-19 69.3 2.6 6.2e-19 67.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 ETS82966.1 - 0.00026 20.9 1.5 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial aa3 type cytochrome c oxidase subunit IV ABC2_membrane_3 PF12698.2 ETS82966.1 - 0.061 12.3 3.5 0.085 11.8 2.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PgaD PF13994.1 ETS82966.1 - 4 6.9 5.7 1.3 8.4 1.6 1.8 1 1 1 2 2 2 0 PgaD-like protein HEAT PF02985.17 ETS82968.1 - 0.037 14.1 0.8 13 6.1 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Daxx PF03344.10 ETS82968.1 - 1.6 7.1 8.2 2.3 6.5 5.7 1.2 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 ETS82968.1 - 3.6 6.4 11.9 5.6 5.7 8.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Nop14 PF04147.7 ETS82968.1 - 6.7 4.5 9.8 4.2 5.1 4.9 2.0 2 0 0 2 2 2 0 Nop14-like family NUDIX PF00293.23 ETS82969.1 - 2e-28 98.7 0.0 3e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AAA_6 PF12774.2 ETS82969.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 Acetyltransf_7 PF13508.1 ETS82970.1 - 4.1e-08 33.2 0.1 6.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS82970.1 - 1e-05 25.4 0.2 1.8e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS82970.1 - 4.9e-05 23.1 0.1 9.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS82970.1 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS82970.1 - 0.0059 16.7 0.1 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RPA_C PF08784.6 ETS82971.1 - 1.6e-15 57.3 0.6 1.6e-15 57.3 0.4 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 ETS82971.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lon_C PF05362.8 ETS82972.1 - 6.5e-64 215.0 0.1 1.3e-63 214.0 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 ETS82972.1 - 1.6e-26 93.2 0.1 3.9e-26 92.0 0.0 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 ETS82972.1 - 8.1e-23 81.0 0.0 2.3e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 ETS82972.1 - 1e-08 34.7 0.1 4.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 ETS82972.1 - 5.9e-08 32.5 0.0 1.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS82972.1 - 3.4e-06 27.1 0.0 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS82972.1 - 3.3e-05 24.6 0.0 9.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS82972.1 - 4.1e-05 22.7 0.0 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS82972.1 - 4.2e-05 23.2 0.1 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 ETS82972.1 - 5.7e-05 22.0 0.1 0.00014 20.7 0.1 1.7 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 ETS82972.1 - 0.0002 20.9 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS82972.1 - 0.00022 21.3 0.0 0.0051 16.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETS82972.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 ETS82972.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETS82972.1 - 0.0065 16.4 0.0 0.032 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 ETS82972.1 - 0.0066 16.7 0.1 0.0066 16.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS82972.1 - 0.0099 14.9 0.0 0.028 13.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 ETS82972.1 - 0.011 14.9 0.2 0.05 12.7 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 ETS82972.1 - 0.016 15.5 0.1 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 ETS82972.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 ETS82972.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS82972.1 - 0.026 14.6 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 ETS82972.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETS82972.1 - 0.038 13.2 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 ETS82972.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 ETS82972.1 - 0.051 13.2 0.2 0.41 10.2 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_PrkA PF08298.6 ETS82972.1 - 0.061 12.0 0.1 0.78 8.3 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain ABC_tran PF00005.22 ETS82972.1 - 0.094 13.0 1.1 1.7 8.9 0.0 3.1 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.12 ETS82972.1 - 0.14 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 ETS82972.1 - 0.19 11.2 2.1 0.39 10.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain Zn_clus PF00172.13 ETS82973.1 - 8.1e-07 28.8 10.9 1.3e-06 28.2 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.5 ETS82973.1 - 0.027 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold DNA_mis_repair PF01119.14 ETS82975.1 - 1.1e-33 115.1 0.3 1.8e-33 114.5 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 ETS82975.1 - 6e-14 51.8 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETS82975.1 - 1.7e-10 40.5 0.0 4.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.26 ETS82976.1 - 6.2e-14 51.4 0.7 6.2e-14 51.4 0.5 2.2 3 1 1 4 4 4 1 DnaJ domain DEAD PF00270.24 ETS82977.1 - 4.1e-46 156.5 0.0 2.5e-45 153.9 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS82977.1 - 1.4e-21 76.1 0.0 3.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 ETS82977.1 - 2.6e-21 75.2 2.7 6.5e-21 73.9 1.9 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 ETS82977.1 - 3.2e-05 23.8 0.0 9.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 ETS82977.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Fungal_trans PF04082.13 ETS82978.1 - 2.5e-13 49.5 0.5 1e-12 47.5 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Raptor_N PF14538.1 ETS82979.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain PAN_4 PF14295.1 ETS82981.1 - 0.0013 18.3 1.3 0.0044 16.7 0.5 2.3 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.6 ETS82981.1 - 0.018 14.8 1.0 0.054 13.3 0.7 1.8 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.21 ETS82981.1 - 0.07 12.9 1.9 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 PAN domain ADH_zinc_N PF00107.21 ETS82982.1 - 3.2e-29 101.1 0.0 5.8e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS82982.1 - 1.2e-16 61.7 0.0 2.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS82982.1 - 1.7e-11 43.8 0.0 7.7e-10 38.5 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 ETS82982.1 - 0.041 13.8 0.4 0.076 13.0 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding Aldo_ket_red PF00248.16 ETS82983.1 - 1.8e-65 220.6 0.0 2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 ETS82984.1 - 2.4e-16 60.1 0.5 1.4e-15 57.6 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82984.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS82984.1 - 1.1e-05 25.1 0.2 3.1e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82984.1 - 0.032 13.6 0.0 0.24 10.7 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS82985.1 - 1.1e-17 64.6 0.2 1.5e-17 64.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS82985.1 - 9.5e-06 25.2 0.0 2.7e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS82985.1 - 0.0002 20.6 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 ETS82985.1 - 0.011 14.6 0.1 0.02 13.8 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 ETS82985.1 - 0.082 12.8 0.4 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase adh_short PF00106.20 ETS82986.1 - 4.8e-30 104.6 0.0 6.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS82986.1 - 4.2e-20 72.5 0.0 6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS82986.1 - 4.6e-09 36.5 0.0 7.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS82986.1 - 3e-08 33.5 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS82986.1 - 0.002 17.5 0.1 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS82986.1 - 0.003 16.8 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 ETS82986.1 - 0.0052 16.5 0.1 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 ETS82986.1 - 0.011 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AP_endonuc_2 PF01261.19 ETS82986.1 - 0.084 12.1 0.0 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel F420_oxidored PF03807.12 ETS82986.1 - 0.13 12.7 0.0 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 ETS82987.1 - 9.8e-15 54.1 1.1 2.6e-14 52.7 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 ETS82988.1 - 4.8e-25 88.8 0.0 7.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS82988.1 - 7.5e-11 41.5 0.0 5.8e-08 32.0 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS82988.1 - 3.1e-07 30.4 0.0 7.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS82988.1 - 4.2e-07 29.8 0.0 9.2e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding CDO_I PF05995.7 ETS82989.1 - 2e-37 128.0 0.2 2.5e-37 127.7 0.2 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 ETS82989.1 - 0.0003 20.1 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) PQQ_3 PF13570.1 ETS82990.1 - 0.031 14.5 1.7 20 5.6 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Fungal_trans_2 PF11951.3 ETS82991.1 - 1.5e-09 37.0 1.9 1.5e-09 36.9 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain 4HB_MCP_1 PF12729.2 ETS82993.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Terpene_synth_C PF03936.11 ETS82994.1 - 5.7e-13 48.7 0.0 7.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 ETS82996.1 - 6.2e-15 55.5 0.6 6.8e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS82996.1 - 1.5e-06 28.0 0.9 3.7e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS82996.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TMEM154 PF15102.1 ETS82997.1 - 0.018 14.7 0.3 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 ETS82997.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 ETS82997.1 - 0.15 11.3 1.1 0.31 10.3 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_Coat_B PF05356.6 ETS82997.1 - 0.38 10.4 4.1 0.62 9.7 2.5 1.6 1 1 0 1 1 1 0 Phage Coat protein B Aldo_ket_red PF00248.16 ETS82998.1 - 1.2e-34 119.4 0.0 1.3e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 ETS82999.1 - 3.7e-23 82.2 0.3 6.2e-23 81.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.8 ETS83001.1 - 1.1e-32 113.3 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS83001.1 - 7.6e-12 44.5 0.0 2.7e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 ETS83001.1 - 0.0043 16.3 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Pyr_redox_3 PF13738.1 ETS83002.1 - 2.9e-20 73.1 0.0 2e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83002.1 - 3.3e-10 39.8 0.0 2.2e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS83002.1 - 1.3e-08 34.1 0.0 3.3e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 ETS83002.1 - 5.3e-08 31.5 0.0 1.2e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 ETS83002.1 - 1.3e-06 27.5 0.1 6.1e-05 22.1 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS83002.1 - 1.1e-05 25.4 1.1 0.064 13.1 0.0 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS83002.1 - 2.9e-05 23.1 0.1 0.0028 16.6 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS83002.1 - 0.00017 20.7 0.0 0.0074 15.4 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.1 ETS83002.1 - 0.00031 20.5 0.2 0.89 9.3 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS83002.1 - 0.0013 19.1 0.2 0.28 11.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS83002.1 - 0.023 13.5 0.2 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A CPSase_L_chain PF00289.17 ETS83002.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 ETS83002.1 - 0.53 8.7 1.7 1.1 7.6 0.0 2.3 4 0 0 4 4 4 0 HI0933-like protein Baculo_LEF-10 PF07206.6 ETS83004.1 - 0.028 14.0 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) HET PF06985.6 ETS83004.1 - 0.064 13.4 1.6 2.1 8.5 0.1 2.6 1 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 ETS83005.1 - 1.4e-13 50.5 28.4 6.3e-07 29.2 0.4 7.0 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 ETS83005.1 - 9.4e-12 44.4 13.8 0.00015 21.2 0.9 5.1 5 0 0 5 5 5 3 TPR repeat TPR_16 PF13432.1 ETS83005.1 - 3.5e-11 43.4 15.2 1.6e-05 25.4 1.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS83005.1 - 1.4e-10 41.3 13.0 9.4e-05 22.6 1.0 4.7 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83005.1 - 1.1e-09 37.4 19.6 0.0052 16.6 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS83005.1 - 3.1e-09 36.8 13.2 0.0023 18.0 0.8 5.5 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETS83005.1 - 2.4e-08 33.8 17.5 0.021 15.4 0.0 7.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS83005.1 - 9.5e-08 31.7 13.9 0.1 12.5 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83005.1 - 9e-07 28.2 12.6 0.023 14.4 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS83005.1 - 1.5e-05 24.9 10.4 0.52 10.8 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 ETS83005.1 - 3.8e-05 23.8 12.3 0.03 14.7 0.2 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 ETS83005.1 - 0.00012 22.0 3.6 2.4 8.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS83005.1 - 0.00029 20.6 2.1 0.038 13.8 0.6 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS83005.1 - 0.00031 20.5 1.1 0.15 11.9 0.1 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 ETS83005.1 - 0.0041 16.8 11.2 0.41 10.5 0.2 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS83005.1 - 0.0042 16.6 15.6 0.043 13.4 0.2 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETS83005.1 - 0.0056 16.7 6.8 0.013 15.6 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat BTAD PF03704.12 ETS83005.1 - 0.011 16.0 7.6 0.14 12.4 0.4 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_17 PF13431.1 ETS83005.1 - 0.23 11.7 8.1 8.4 6.8 0.4 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS83006.1 - 3.7e-18 65.3 41.6 1.5e-17 63.4 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83006.1 - 0.00041 19.0 28.6 0.0092 14.5 19.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Pribosyltran_N PF13793.1 ETS83007.1 - 5.3e-40 135.7 0.0 2.1e-39 133.8 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 ETS83007.1 - 7.3e-35 120.3 0.0 7.6e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 ETS83007.1 - 1.5e-06 27.9 0.0 0.00049 19.8 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.1 ETS83007.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase XPG_I_2 PF12813.2 ETS83008.1 - 7.7e-36 123.8 0.0 1.8e-35 122.6 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 ETS83008.1 - 0.025 14.8 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Anoctamin PF04547.7 ETS83009.1 - 3.7e-123 411.5 5.3 4.7e-123 411.1 3.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.23 ETS83010.1 - 9.9e-08 31.6 2.8 0.0007 19.0 0.2 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS83010.1 - 0.00011 22.1 0.1 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WSC PF01822.14 ETS83011.1 - 1.4e-10 40.9 10.9 1.4e-10 40.9 7.6 3.1 3 0 0 3 3 3 1 WSC domain Glyco_hydro_16 PF00722.16 ETS83011.1 - 9.7e-07 28.2 0.6 1.7e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 ETS83012.1 - 4.5e-15 55.5 0.0 6.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83012.1 - 2.2e-10 40.0 0.0 2.5e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Endonuc-FokI_C PF09254.6 ETS83012.1 - 0.0048 16.0 0.2 0.0082 15.2 0.1 1.4 1 1 0 1 1 1 1 Restriction endonuclease FokI, C terminal Kdo PF06293.9 ETS83012.1 - 0.034 13.2 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase PF00330.15 ETS83013.1 - 1.8e-70 237.7 0.2 1.2e-44 152.6 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS83013.1 - 1.2e-24 86.8 0.0 4.4e-24 85.0 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain Carn_acyltransf PF00755.15 ETS83014.1 - 1.1e-173 578.6 0.0 1.2e-173 578.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 ETS83015.1 - 1.5e-88 297.1 9.8 5.8e-88 295.1 6.8 1.7 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 ETS83015.1 - 2.1e-55 186.3 0.3 2.9e-55 185.9 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PfkB PF00294.19 ETS83016.1 - 3.1e-14 52.7 0.0 2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 ETS83016.1 - 0.14 11.3 0.2 1.4 8.0 0.0 2.3 3 0 0 3 3 3 0 Phosphomethylpyrimidine kinase GFO_IDH_MocA PF01408.17 ETS83017.1 - 4.6e-17 62.6 0.0 8.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 ETS83017.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain BCA_ABC_TP_C PF12399.3 ETS83017.1 - 0.23 11.1 1.9 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Ank_4 PF13637.1 ETS83018.1 - 2.4e-47 158.5 13.7 2.9e-10 40.3 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS83018.1 - 5.4e-47 158.0 15.2 2.1e-23 82.4 1.9 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83018.1 - 7.6e-46 151.7 16.6 3.1e-09 36.1 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 ETS83018.1 - 3e-38 126.0 8.0 3.5e-07 29.8 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 ETS83018.1 - 1.5e-28 98.1 15.9 1.6e-05 24.9 0.1 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 ETS83018.1 - 0.00032 20.2 0.2 0.071 12.6 0.0 2.8 1 1 2 3 3 3 1 Shigella flexneri OspC protein FA PF08736.6 ETS83018.1 - 0.059 13.1 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 FERM adjacent (FA) RVP PF00077.15 ETS83018.1 - 0.13 12.1 1.4 26 4.8 0.0 3.1 2 1 1 3 3 3 0 Retroviral aspartyl protease DUF1771 PF08590.5 ETS83018.1 - 2.7 8.0 7.9 20 5.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) MMS1_N PF10433.4 ETS83019.1 - 1.9e-87 293.5 0.1 3.1e-87 292.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 ETS83019.1 - 3.3e-65 220.2 0.0 7e-65 219.2 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Fungal_trans_2 PF11951.3 ETS83020.1 - 4.1e-08 32.2 0.0 8.2e-08 31.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Rieske PF00355.21 ETS83022.1 - 2e-18 65.7 0.0 3.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 ETS83022.1 - 3.3e-17 62.4 0.7 3.3e-17 62.4 0.5 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region ABM PF03992.11 ETS83023.1 - 0.043 13.8 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF1049 PF06305.6 ETS83024.1 - 0.42 10.1 2.4 3.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3784 PF12650.2 ETS83024.1 - 2.3 8.2 6.7 1.9 8.5 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) EF-hand_1 PF00036.27 ETS83025.1 - 1.3e-34 114.8 12.3 1.1e-08 33.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 ETS83025.1 - 7.4e-30 102.8 8.0 1.2e-16 60.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 ETS83025.1 - 1.9e-27 92.5 7.7 5.6e-09 35.1 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 ETS83025.1 - 1.3e-26 91.9 6.3 7.7e-12 44.6 0.4 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 ETS83025.1 - 9.3e-20 69.0 14.3 1.1e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 ETS83025.1 - 3.5e-17 62.0 0.2 1.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 ETS83025.1 - 2.5e-09 36.7 3.4 0.00062 19.4 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 ETS83025.1 - 9.9e-06 25.5 0.1 0.078 13.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.1 ETS83025.1 - 0.0018 18.5 0.9 0.8 10.0 0.0 2.3 2 0 0 2 2 2 2 Toprim-like UPF0154 PF03672.8 ETS83025.1 - 0.0027 17.2 0.0 0.13 11.9 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) TerB PF05099.8 ETS83025.1 - 0.0066 16.1 0.3 0.9 9.2 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.5 ETS83025.1 - 0.013 15.4 1.8 0.28 11.1 0.0 2.5 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF3164 PF11363.3 ETS83025.1 - 0.027 13.8 0.6 0.46 9.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3164) DUF3349 PF11829.3 ETS83025.1 - 0.029 14.7 0.2 0.93 9.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) SpoVIF PF14069.1 ETS83025.1 - 0.041 13.6 0.2 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Stage VI sporulation protein F Tenui_NCP PF04876.7 ETS83025.1 - 0.065 12.7 0.3 4.8 6.6 0.0 2.3 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein GTPase_Cys_C PF12631.2 ETS83025.1 - 0.11 12.9 0.4 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MgtE_N PF03448.12 ETS83025.1 - 0.6 10.4 4.0 2.4 8.5 0.4 2.2 1 1 1 2 2 2 0 MgtE intracellular N domain EF-hand_10 PF14788.1 ETS83025.1 - 0.65 9.6 5.7 0.81 9.3 0.1 3.3 1 1 4 5 5 5 0 EF hand Ribosomal_L11_N PF03946.9 ETS83026.1 - 1.7e-25 88.2 0.0 4e-25 87.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 ETS83026.1 - 1.1e-24 86.3 1.0 1.7e-24 85.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 ETS83027.1 - 2.5e-125 417.7 0.0 3e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 Svf1-like KH_4 PF13083.1 ETS83027.1 - 0.044 13.4 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 KH domain Histone PF00125.19 ETS83028.1 - 3.1e-10 40.0 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acetyltransf_1 PF00583.19 ETS83029.1 - 0.0006 19.7 0.2 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS83029.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.1 ETS83030.1 - 0.23 11.8 13.7 0.8 10.1 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_23 PF13476.1 ETS83031.1 - 8.2 6.6 12.2 6.9 6.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain DHC_N1 PF08385.7 ETS83032.1 - 1.5e-188 627.8 7.7 1.5e-188 627.8 5.4 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 ETS83032.1 - 4.2e-117 391.1 8.4 4.2e-117 391.1 5.8 5.2 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 ETS83032.1 - 1.5e-106 357.1 1.2 2.3e-106 356.5 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 ETS83032.1 - 2.2e-73 246.5 0.0 4.7e-73 245.5 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 ETS83032.1 - 1.6e-46 158.6 9.5 1.2e-45 155.8 6.4 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 ETS83032.1 - 4.6e-43 146.6 0.0 4.6e-43 146.6 0.0 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 ETS83032.1 - 4.7e-40 137.2 0.8 9.7e-39 132.9 0.1 3.1 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 ETS83032.1 - 4.1e-32 110.7 0.0 7.4e-12 45.1 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 ETS83032.1 - 1.9e-21 76.3 0.0 2.1e-19 69.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 ETS83032.1 - 1.1e-13 51.4 0.0 0.017 15.2 0.0 6.5 6 0 0 6 6 4 3 AAA domain AAA PF00004.24 ETS83032.1 - 2.5e-13 50.3 0.0 0.0019 18.3 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS83032.1 - 5.3e-11 42.8 1.0 0.086 12.8 0.1 7.4 5 1 1 6 6 6 2 AAA ATPase domain AAA_17 PF13207.1 ETS83032.1 - 2.5e-10 41.2 0.6 0.028 15.2 0.0 6.2 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 ETS83032.1 - 1e-09 38.4 0.0 0.29 10.9 0.0 5.5 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 ETS83032.1 - 5.1e-09 36.5 0.4 0.038 14.2 0.0 5.8 5 0 0 5 5 4 2 AAA domain T2SE PF00437.15 ETS83032.1 - 4.6e-06 25.7 0.0 0.15 10.9 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 ETS83032.1 - 5.2e-06 26.1 0.3 0.93 9.2 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 ETS83032.1 - 1.7e-05 24.2 0.0 2.1 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 ETS83032.1 - 3.9e-05 22.8 0.4 0.41 9.7 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 ETS83032.1 - 9.5e-05 22.7 0.0 4.8 7.4 0.0 4.7 3 0 0 3 3 3 2 ABC transporter FtsK_SpoIIIE PF01580.13 ETS83032.1 - 0.0002 20.8 0.0 3 7.2 0.0 4.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 ETS83032.1 - 0.0031 17.2 0.2 12 5.5 0.0 4.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 ETS83032.1 - 0.013 15.6 0.0 40 4.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase IncA PF04156.9 ETS83032.1 - 1.3 8.6 43.8 0.012 15.2 4.2 5.0 5 0 0 5 5 4 0 IncA protein Reo_sigmaC PF04582.7 ETS83032.1 - 1.4 8.0 18.8 0.78 8.8 0.6 4.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Rad60-SLD PF11976.3 ETS83033.1 - 2.3e-12 46.4 0.1 4.4e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETS83033.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin family SH3_1 PF00018.23 ETS83033.1 - 0.098 12.0 0.4 0.18 11.2 0.3 1.4 1 0 0 1 1 1 0 SH3 domain PEX11 PF05648.9 ETS83034.1 - 0.0075 15.5 3.7 2.7 7.1 0.0 3.2 3 0 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) Rifin_STEVOR PF02009.11 ETS83035.1 - 0.79 9.3 3.8 0.87 9.1 2.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF2392 PF10288.4 ETS83036.1 - 3.9e-19 68.9 0.0 7.5e-14 51.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2392) Mito_carr PF00153.22 ETS83037.1 - 1.5e-61 204.1 2.8 1.1e-20 73.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FHA PF00498.21 ETS83038.1 - 1.7e-15 56.9 0.0 3.3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 ETS83038.1 - 3.7e-07 29.8 9.3 5.8e-07 29.2 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS83038.1 - 0.00046 20.2 4.8 0.00085 19.3 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 ETS83038.1 - 0.0011 18.5 9.4 0.0019 17.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS83038.1 - 0.0052 16.4 6.8 0.0083 15.8 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS83038.1 - 0.012 15.2 6.3 0.02 14.5 4.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 ETS83038.1 - 0.055 13.4 5.1 0.093 12.7 3.5 1.4 1 0 0 1 1 1 0 RING-like domain lci PF12197.3 ETS83038.1 - 0.077 12.5 0.4 0.21 11.2 0.3 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein zf-C3HC4_2 PF13923.1 ETS83038.1 - 0.15 12.0 10.7 0.25 11.3 7.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 ETS83038.1 - 0.19 11.4 4.4 0.35 10.6 3.0 1.4 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_43 PF04616.9 ETS83039.1 - 0.00017 20.7 3.6 0.00025 20.2 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GBP PF02263.14 ETS83039.1 - 0.15 11.0 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Glyco_hydro_76 PF03663.9 ETS83040.1 - 1.6e-142 475.3 23.4 2e-142 474.9 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS83040.1 - 0.0046 16.0 8.9 0.28 10.1 0.8 3.5 2 1 1 4 4 4 3 Glycosyl Hydrolase Family 88 Lipase_GDSL PF00657.17 ETS83041.1 - 8.4e-17 61.7 0.2 1.2e-16 61.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS83041.1 - 2.4e-11 44.1 1.5 3.7e-11 43.4 1.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PGAP1 PF07819.8 ETS83042.1 - 0.0034 16.9 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS83042.1 - 0.0055 16.0 0.0 0.0095 15.2 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 ETS83042.1 - 0.0071 16.2 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 ETS83042.1 - 0.019 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Podoplanin PF05808.6 ETS83043.1 - 0.0011 18.5 2.1 0.0019 17.7 1.4 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.2 ETS83043.1 - 0.0096 15.1 0.0 0.021 14.0 0.0 1.4 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Pex14_N PF04695.8 ETS83043.1 - 0.012 15.6 3.3 0.027 14.5 2.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha_GJ PF03229.8 ETS83043.1 - 0.84 9.9 14.2 2.3 8.5 9.6 2.0 1 1 0 1 1 1 0 Alphavirus glycoprotein J Mucin PF01456.12 ETS83043.1 - 1.9 8.2 26.4 3.8 7.2 18.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 ETS83043.1 - 2 6.5 6.6 2.4 6.3 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein TP_methylase PF00590.15 ETS83044.1 - 1.6e-21 77.0 0.1 2.6e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 ETS83045.1 - 8.2e-09 35.3 0.2 1.7e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS83045.1 - 1.6e-05 24.9 0.3 3.1e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 ETS83045.1 - 0.00017 21.3 5.5 0.00017 21.3 3.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 ETS83045.1 - 0.0021 17.6 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger LPP20 PF02169.11 ETS83045.1 - 0.41 10.7 4.6 1.2 9.2 0.5 2.7 2 1 0 2 2 2 0 LPP20 lipoprotein F-box-like PF12937.2 ETS83046.1 - 0.008 15.8 0.3 0.039 13.6 0.2 2.1 1 1 0 1 1 1 1 F-box-like DUF3436 PF11918.3 ETS83046.1 - 0.11 12.7 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) Pyridox_oxidase PF01243.15 ETS83047.1 - 3.4e-10 39.8 0.0 8.2e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase YjbE PF11106.3 ETS83049.1 - 0.18 11.8 8.3 0.68 9.9 5.8 2.0 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE S1-P1_nuclease PF02265.11 ETS83050.1 - 1.6e-73 247.4 1.2 1.8e-73 247.2 0.8 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Sugar_tr PF00083.19 ETS83051.1 - 0.0082 14.7 4.3 0.0093 14.5 3.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Esterase PF00756.15 ETS83052.1 - 1.7e-07 30.8 0.2 7.5e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Putative esterase CBM_48 PF02922.13 ETS83052.1 - 0.013 15.5 0.6 2.5 8.2 0.0 2.6 1 1 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Big_3_4 PF13754.1 ETS83052.1 - 3.1 8.1 8.1 0.12 12.6 0.6 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ank_2 PF12796.2 ETS83053.1 - 2.4e-13 50.2 0.0 9.1e-07 29.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83053.1 - 1.3e-07 31.0 0.3 0.011 15.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 ETS83053.1 - 5e-07 29.7 0.0 0.03 14.5 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS83053.1 - 2.9e-06 27.6 0.0 0.0058 17.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83053.1 - 0.00025 20.9 0.0 0.047 13.9 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat PPR_3 PF13812.1 ETS83053.1 - 0.07 13.4 0.1 44 4.7 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Ank_2 PF12796.2 ETS83054.1 - 1.3e-22 79.9 0.1 6.1e-11 42.5 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83054.1 - 2.1e-17 61.9 1.5 0.00093 18.8 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 ETS83054.1 - 1.7e-15 56.6 3.2 4.4e-06 26.7 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83054.1 - 2.4e-15 55.1 2.3 0.023 14.9 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 ETS83054.1 - 7.6e-14 51.7 3.0 2.2e-08 34.3 0.0 5.0 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Transp_cyt_pur PF02133.10 ETS83055.1 - 7.1e-25 87.4 39.7 1.1e-24 86.8 27.5 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cupin_1 PF00190.17 ETS83056.1 - 3.7e-24 84.8 0.0 2.5e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 ETS83056.1 - 1.2e-22 79.1 0.3 8.6e-12 44.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 ETS83056.1 - 5.3e-08 32.1 0.0 0.0032 16.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS83056.1 - 6.4e-06 25.9 0.0 0.00012 21.7 0.0 2.5 3 0 0 3 3 3 1 AraC-like ligand binding domain 3-HAO PF06052.7 ETS83056.1 - 0.00032 20.1 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase MannoseP_isomer PF01050.13 ETS83056.1 - 0.002 17.7 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase DUF1971 PF09313.6 ETS83056.1 - 0.0024 17.5 0.0 0.0067 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1971) FdtA PF05523.6 ETS83056.1 - 0.0032 16.9 0.0 0.066 12.7 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal Cupin_6 PF12852.2 ETS83056.1 - 0.034 13.7 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Cupin Asp PF00026.18 ETS83057.1 - 2.2e-47 161.8 0.3 2.7e-47 161.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS83057.1 - 0.0002 21.3 0.1 0.00079 19.4 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS83057.1 - 0.00042 20.7 1.2 0.51 10.8 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 ETS83057.1 - 0.057 12.9 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal UQ_con PF00179.21 ETS83058.1 - 7.7e-38 129.0 0.0 9.7e-38 128.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS83058.1 - 0.057 13.3 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 ETS83058.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.1 ETS83059.1 - 3.7e-25 88.6 0.0 1.3e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 ETS83059.1 - 6e-06 25.7 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETS83059.1 - 0.042 14.1 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.16 ETS83060.1 - 1e-59 201.9 2.4 1.5e-59 201.4 1.7 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 ETS83060.1 - 1.4e-07 30.9 9.4 1.4e-07 30.9 6.5 4.3 2 2 2 4 4 4 1 ZIP Zinc transporter Mito_carr PF00153.22 ETS83062.1 - 2e-60 200.4 2.9 6.7e-21 73.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.17 ETS83063.1 - 5e-08 33.1 0.0 3.8e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Lipase_GDSL PF00657.17 ETS83064.1 - 2.6e-20 73.2 0.4 3.2e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS83064.1 - 1.6e-07 31.6 0.4 2.6e-07 30.9 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_2_N PF02837.13 ETS83065.1 - 3.7e-34 117.7 2.4 2.2e-33 115.2 0.1 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 ETS83065.1 - 2.1e-27 95.7 0.0 3.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETS83065.1 - 1.5e-11 44.7 0.0 3.8e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 ETS83065.1 - 0.00053 20.2 0.2 0.0027 17.9 0.1 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 ETS83065.1 - 0.0032 17.3 1.2 0.012 15.4 0.1 2.5 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) Glyco_hydro_43 PF04616.9 ETS83066.1 - 5.9e-68 229.0 0.5 7.6e-68 228.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 ETS83066.1 - 0.021 14.2 0.0 4.1 6.6 0.0 2.6 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain DnaJ PF00226.26 ETS83067.1 - 8.3e-09 35.0 0.7 2e-08 33.8 0.5 1.7 1 1 0 1 1 1 1 DnaJ domain Ferric_reduct PF01794.14 ETS83068.1 - 2.7e-08 33.9 5.0 7.8e-08 32.4 3.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS83068.1 - 1e-07 32.0 0.4 0.002 18.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS83068.1 - 2.7e-05 23.9 0.4 0.00059 19.6 0.0 2.6 3 1 0 3 3 3 1 FAD-binding domain DUF420 PF04238.7 ETS83068.1 - 0.015 15.2 5.1 0.039 13.8 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF420) NAD_binding_1 PF00175.16 ETS83068.1 - 0.05 14.1 1.5 4.4 7.9 1.0 2.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain peroxidase PF00141.18 ETS83069.1 - 2e-30 105.9 0.0 3.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 ETS83069.1 - 0.028 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) TPR_11 PF13414.1 ETS83070.1 - 0.00074 19.1 0.9 0.53 9.9 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_20 PF14561.1 ETS83070.1 - 0.0014 18.7 0.7 0.013 15.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS83070.1 - 0.016 15.4 2.4 0.95 9.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83070.1 - 0.022 14.6 3.0 13 5.9 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS83070.1 - 0.03 14.9 8.8 0.045 14.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SoxZ PF08770.6 ETS83070.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ GMC_oxred_C PF05199.8 ETS83071.1 - 0.00082 19.6 0.0 0.001 19.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Dynamin_N PF00350.18 ETS83072.1 - 6e-13 48.9 0.7 1.4e-12 47.8 0.5 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS83072.1 - 1.9e-05 23.6 0.0 4.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 ETS83072.1 - 0.0012 19.3 0.3 0.021 15.3 0.2 2.6 1 1 0 1 1 1 1 Miro-like protein GED PF02212.13 ETS83072.1 - 0.002 17.9 0.3 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS83072.1 - 0.0029 17.5 1.4 0.015 15.2 1.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS83072.1 - 0.0068 15.6 0.6 0.026 13.7 0.3 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_23 PF13476.1 ETS83072.1 - 0.0094 16.2 1.8 0.023 15.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 ETS83072.1 - 0.032 13.7 0.0 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GAT PF03127.9 ETS83072.1 - 0.048 13.6 1.3 0.21 11.6 0.7 2.2 2 0 0 2 2 2 0 GAT domain Arch_ATPase PF01637.13 ETS83072.1 - 0.07 12.8 0.2 0.46 10.1 0.1 2.4 1 1 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 ETS83072.1 - 0.093 11.9 0.1 8 5.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.17 ETS83072.1 - 0.1 11.9 0.1 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 ETS83072.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_63 PF03200.11 ETS83073.1 - 9.6e-181 602.5 0.1 3.3e-179 597.4 0.0 2.5 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 ETS83073.1 - 2e-09 36.6 0.0 2.9e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 ETS83073.1 - 7.8e-06 24.7 0.0 1.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Trehalase MFS_1 PF07690.11 ETS83074.1 - 1.7e-31 109.2 29.1 6.4e-30 104.0 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycophorin_A PF01102.13 ETS83074.1 - 0.041 13.6 0.3 0.79 9.5 0.4 2.4 2 0 0 2 2 2 0 Glycophorin A RseC_MucC PF04246.7 ETS83074.1 - 0.42 10.1 4.7 3.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC p450 PF00067.17 ETS83075.1 - 1.4e-19 69.9 0.1 3.5e-19 68.6 0.0 1.6 1 1 1 2 2 2 2 Cytochrome P450 COesterase PF00135.23 ETS83076.1 - 6.1e-94 315.6 0.0 7.8e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS83076.1 - 2.9e-06 27.0 0.0 0.00052 19.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS83077.1 - 1.9e-06 27.6 0.2 2.7e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS83077.1 - 0.016 14.7 0.6 0.028 14.0 0.4 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS83077.1 - 0.016 14.4 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 ETS83077.1 - 0.064 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) APH PF01636.18 ETS83078.1 - 2e-23 83.4 0.0 2.6e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS83078.1 - 6.8e-05 22.5 0.0 0.0001 21.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETS83078.1 - 0.00051 19.4 0.1 0.053 12.8 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.9 ETS83078.1 - 0.0028 16.6 0.0 0.0084 15.1 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase WD40 PF00400.27 ETS83080.1 - 4e-118 381.5 20.1 5.5e-13 48.2 0.0 19.0 19 0 0 19 19 19 14 WD domain, G-beta repeat NACHT PF05729.7 ETS83080.1 - 4.3e-18 65.5 0.0 9.1e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 ETS83080.1 - 6.6e-13 48.0 7.6 0.12 12.0 0.1 10.2 12 0 0 12 12 11 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 ETS83080.1 - 3.2e-12 46.5 0.0 0.013 15.2 0.0 6.4 4 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 ETS83080.1 - 4.5e-07 28.3 15.3 0.039 12.0 0.0 6.3 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 ETS83080.1 - 7.6e-07 27.7 4.5 0.0084 14.4 0.1 5.4 4 1 2 6 6 6 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 ETS83080.1 - 2e-06 26.9 13.2 3.3 7.1 0.0 8.1 7 0 0 7 7 7 2 Proteasome subunit A N-terminal signature AAA_16 PF13191.1 ETS83080.1 - 0.00013 21.9 0.0 0.00066 19.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Nucleoporin_N PF08801.6 ETS83080.1 - 0.00068 18.4 6.7 0.077 11.7 0.1 5.0 3 2 0 4 4 4 1 Nup133 N terminal like Robl_LC7 PF03259.12 ETS83080.1 - 0.0025 17.3 0.0 2.9 7.4 0.0 4.8 6 0 0 6 6 6 1 Roadblock/LC7 domain RNA_helicase PF00910.17 ETS83080.1 - 0.0079 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 ETS83080.1 - 0.088 12.9 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DPPIV_N PF00930.16 ETS83080.1 - 0.11 11.0 0.1 30 3.0 0.0 4.5 4 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF676 PF05057.9 ETS83080.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2075 PF09848.4 ETS83080.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1993 PF09351.5 ETS83082.1 - 8.1e-41 139.6 0.0 9.1e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DHquinase_I PF01487.10 ETS83083.1 - 1.8e-27 96.4 0.0 3.5e-27 95.5 0.0 1.4 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 ETS83083.1 - 7.6e-17 61.1 0.0 2.4e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 ETS83083.1 - 3e-15 56.4 0.0 6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 ETS83083.1 - 6.4e-13 48.9 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Poxvirus_B22R_C PF13168.1 ETS83083.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal F420_oxidored PF03807.12 ETS83083.1 - 0.13 12.6 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 ETS83083.1 - 0.15 11.8 0.6 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 ThiF family Zn_clus PF00172.13 ETS83084.1 - 1.7e-06 27.8 10.9 2.6e-06 27.2 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L33 PF00471.15 ETS83086.1 - 0.078 13.2 1.0 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L33 PQ-loop PF04193.9 ETS83088.1 - 1.5e-16 59.6 17.4 5.8e-14 51.3 0.4 2.9 3 0 0 3 3 3 2 PQ loop repeat Claudin_2 PF13903.1 ETS83088.1 - 0.025 14.2 0.0 0.025 14.2 0.0 2.7 3 2 1 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Syndecan PF01034.15 ETS83088.1 - 0.12 12.0 0.3 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain Oxidored_q4 PF00507.14 ETS83088.1 - 0.14 11.9 2.9 0.73 9.6 0.0 3.0 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 ER_lumen_recept PF00810.13 ETS83088.1 - 0.17 12.3 1.8 0.28 11.6 0.3 2.0 2 1 0 2 2 2 0 ER lumen protein retaining receptor EphA2_TM PF14575.1 ETS83088.1 - 0.21 12.0 0.9 5.4 7.4 0.0 3.2 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF4131 PF13567.1 ETS83088.1 - 0.22 10.9 10.1 0.38 10.1 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Jiraiya PF15038.1 ETS83088.1 - 1.1 8.6 5.6 0.55 9.6 0.1 2.7 2 1 0 2 2 2 0 Jiraiya DUF3784 PF12650.2 ETS83088.1 - 6.7 6.7 13.4 2.3 8.2 0.1 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF3784) SH3_9 PF14604.1 ETS83089.1 - 5.2e-07 29.1 0.2 9.7e-07 28.2 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 ETS83089.1 - 0.0004 19.7 0.1 0.00085 18.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain IncA PF04156.9 ETS83089.1 - 0.17 11.4 3.4 0.27 10.8 2.3 1.2 1 0 0 1 1 1 0 IncA protein MtrF PF09472.5 ETS83089.1 - 1.2 8.4 4.5 2.4 7.4 3.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) GST_C PF00043.20 ETS83090.1 - 2e-07 30.8 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS83090.1 - 3.4e-07 30.0 0.0 7.8e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS83090.1 - 0.00018 21.5 0.0 0.00082 19.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS83090.1 - 0.00045 20.6 0.0 0.00072 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS83090.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS83090.1 - 0.004 17.1 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribonucleas_3_3 PF14622.1 ETS83091.1 - 5.8e-08 32.7 0.0 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 ETS83091.1 - 0.00011 22.6 0.0 0.00031 21.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 ETS83091.1 - 0.00039 20.9 0.2 0.00081 19.9 0.0 1.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif PLA2_B PF01735.13 ETS83093.1 - 1.2e-28 99.5 0.0 2.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ctr PF04145.10 ETS83094.1 - 1.2e-14 54.5 0.2 1.6e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Osteopontin PF00865.13 ETS83095.1 - 0.14 11.3 15.2 0.26 10.4 10.5 1.3 1 0 0 1 1 1 0 Osteopontin Peroxidase_2 PF01328.12 ETS83096.1 - 1.3e-44 152.1 1.8 1.6e-44 151.8 1.3 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 TNV_CP PF03898.8 ETS83096.1 - 0.0093 15.0 0.1 0.017 14.1 0.1 1.4 1 0 0 1 1 1 1 Satellite tobacco necrosis virus coat protein DIOX_N PF14226.1 ETS83097.1 - 1.9e-27 96.0 0.1 3.1e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS83097.1 - 2.8e-20 72.4 0.1 1.3e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 ETS83098.1 - 5.8e-103 344.7 33.9 6.7e-103 344.5 23.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DPM3 PF08285.6 ETS83098.1 - 3.9 7.3 6.8 17 5.3 0.2 3.2 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAD_binding_3 PF01494.14 ETS83099.1 - 8.7e-58 196.0 0.0 1.4e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS83099.1 - 4.4e-09 35.7 0.0 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS83099.1 - 5.2e-05 21.8 0.0 0.11 10.9 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 ETS83099.1 - 0.0002 20.4 0.2 0.00042 19.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 ETS83099.1 - 0.00038 19.9 0.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 ETS83099.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS83099.1 - 0.018 15.4 0.0 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS83099.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 ETS83099.1 - 0.034 14.2 0.0 0.23 11.4 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS83099.1 - 0.065 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DivIC PF04977.10 ETS83099.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator adh_short PF00106.20 ETS83100.1 - 7.4e-25 87.7 0.2 9.5e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83100.1 - 6.1e-19 68.7 0.0 8.3e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83100.1 - 3.9e-09 36.4 0.5 5.7e-09 35.8 0.3 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS83100.1 - 0.00035 20.6 0.2 0.0037 17.3 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS83100.1 - 0.0053 16.5 0.6 0.0098 15.6 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETS83100.1 - 0.02 14.3 0.2 0.029 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 ETS83100.1 - 0.02 14.9 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 ETS83100.1 - 0.046 12.6 0.1 0.089 11.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 ETS83100.1 - 0.056 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 ETS83101.1 - 8.6e-14 51.9 1.4 1.4e-13 51.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83101.1 - 2.3e-12 46.9 0.1 4e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS83101.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 ETS83101.1 - 0.0018 17.8 0.3 0.0031 17.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 ETS83101.1 - 0.0065 16.0 0.0 0.026 14.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gam PF06064.6 ETS83101.1 - 0.022 14.8 0.0 0.069 13.2 0.0 1.8 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam DUF1100 PF06500.6 ETS83101.1 - 0.064 11.8 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF818 PF05677.7 ETS83101.1 - 0.074 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PhrC_PhrF PF11131.3 ETS83101.1 - 0.43 10.1 2.8 0.88 9.1 1.9 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling zf-C2H2 PF00096.21 ETS83102.1 - 1.4e-12 47.1 26.2 9.4e-05 22.5 0.6 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS83102.1 - 5.1e-09 35.8 18.8 0.00091 19.4 0.7 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS83102.1 - 0.00012 22.2 19.2 0.0005 20.2 1.9 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS83102.1 - 0.015 15.4 12.9 0.1 12.7 0.6 4.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 ETS83102.1 - 0.16 11.7 12.5 1.4 8.7 3.9 3.5 3 1 0 3 3 3 0 BED zinc finger zf-met PF12874.2 ETS83102.1 - 0.27 11.4 5.0 7 6.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS83102.1 - 7.4 6.7 12.7 4 7.6 4.5 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CFEM PF05730.6 ETS83104.1 - 0.0017 18.1 8.1 0.0041 16.8 5.6 1.7 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 ETS83105.1 - 2.9e-31 108.7 0.0 1e-27 97.1 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS83105.1 - 1.9e-25 89.8 0.0 3.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 ETS83105.1 - 0.00034 20.5 0.0 0.0016 18.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS83105.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Med4 PF10018.4 ETS83106.1 - 9.5e-43 145.7 18.4 2.1e-42 144.6 12.7 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 UDPG_MGDP_dh_C PF03720.10 ETS83106.1 - 0.14 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ARGLU PF15346.1 ETS83106.1 - 0.19 11.4 24.5 0.44 10.3 17.0 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Nop53 PF07767.6 ETS83106.1 - 3.1 6.7 17.6 6.1 5.7 9.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MAP7 PF05672.6 ETS83106.1 - 7.2 5.9 32.0 0.85 8.9 19.1 1.6 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family QCR10 PF09796.4 ETS83107.1 - 4.9e-21 74.1 0.1 6.2e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DHO_dh PF01180.16 ETS83108.1 - 1.1e-64 218.2 0.2 1.4e-52 178.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 ETS83108.1 - 0.0015 17.7 1.5 0.32 10.2 0.1 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 ETS83108.1 - 0.39 9.5 4.2 8.3 5.1 2.4 2.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase DIE2_ALG10 PF04922.7 ETS83109.1 - 6.3e-75 252.5 19.6 6.6e-54 183.3 3.7 2.2 2 0 0 2 2 2 2 DIE2/ALG10 family FtsX PF02687.16 ETS83109.1 - 1.5 8.6 0.0 1.5 8.6 0.0 4.8 5 2 1 6 6 6 0 FtsX-like permease family Herpes_BLLF1 PF05109.8 ETS83110.1 - 1.8 6.4 12.7 2.2 6.1 8.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4587 PF15248.1 ETS83110.1 - 9.4 6.9 9.5 23 5.6 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Coatomer_WDAD PF04053.9 ETS83111.1 - 6.8e-167 555.7 0.0 3.8e-166 553.2 0.0 2.1 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 ETS83111.1 - 2e-44 147.8 8.7 2.8e-10 39.6 0.3 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 ETS83111.1 - 5.3e-07 28.1 1.3 0.00091 17.4 0.4 4.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 ETS83111.1 - 0.075 11.2 0.0 0.41 8.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Mannitol_dh_C PF08125.8 ETS83112.1 - 1.6e-49 168.2 0.4 2.2e-49 167.8 0.3 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 ETS83112.1 - 2.9e-19 69.5 2.4 6e-19 68.4 0.0 2.3 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 ETS83112.1 - 0.0018 17.6 2.4 0.0022 17.4 0.1 2.2 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ank_2 PF12796.2 ETS83113.1 - 1.5e-26 92.5 0.2 3.9e-15 55.9 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83113.1 - 4.2e-23 79.9 7.9 2.8e-06 26.8 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 ETS83113.1 - 3.6e-19 68.7 1.3 5.6e-08 33.0 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83113.1 - 1.7e-17 61.7 1.4 0.0026 17.8 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 ETS83113.1 - 6.2e-09 35.8 4.8 0.012 15.8 0.0 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS83113.1 - 2.9e-08 33.9 1.8 7.1e-08 32.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 ETS83113.1 - 1.7e-07 31.0 0.0 4.4e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS83113.1 - 0.00013 22.1 0.1 0.0015 18.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 ETS83113.1 - 0.0071 15.8 1.3 2.5 7.5 0.1 2.4 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 ETS83113.1 - 0.016 14.2 1.6 0.068 12.1 0.3 2.0 1 1 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 ETS83113.1 - 0.017 14.0 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 ETS83113.1 - 0.14 12.3 0.1 0.66 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3 PF00933.16 ETS83114.1 - 1.4e-44 152.3 0.0 2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS83114.1 - 1.1e-43 149.3 0.0 2.4e-43 148.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS83114.1 - 1.2e-22 79.6 0.1 2.2e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 ETS83115.1 - 3.7e-25 88.3 55.2 3.7e-19 68.6 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 ETS83116.1 - 3.3e-11 43.0 1.0 5.6e-11 42.3 0.7 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS83116.1 - 6.8e-09 35.8 0.2 1.1e-08 35.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS83116.1 - 7.8e-07 29.1 0.2 1.3e-06 28.4 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS83116.1 - 8.1e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETS83116.1 - 4.2e-05 23.4 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS83116.1 - 0.00044 20.2 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS83116.1 - 0.0031 17.6 0.1 0.0056 16.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS83116.1 - 0.0052 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 ETS83116.1 - 0.038 13.8 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BCL_N PF04714.8 ETS83116.1 - 0.056 13.0 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Sugar_tr PF00083.19 ETS83117.1 - 9.5e-86 288.1 19.6 1.1e-85 287.9 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83117.1 - 7.3e-23 80.8 41.7 1.1e-18 67.1 4.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS83117.1 - 3.1e-05 22.5 6.3 3.1e-05 22.5 4.4 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein DUF1228 PF06779.9 ETS83117.1 - 0.018 15.0 13.0 0.097 12.7 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) fn3_3 PF14686.1 ETS83117.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Git3 PF11710.3 ETS83118.1 - 2.9e-56 190.2 15.3 4.3e-56 189.6 10.6 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 ETS83118.1 - 5.3e-19 67.7 0.9 5.3e-19 67.7 0.6 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2157 PF09925.4 ETS83118.1 - 6.5e-05 22.5 2.5 0.014 14.9 0.0 3.5 3 0 0 3 3 3 1 Predicted membrane protein (DUF2157) DUF2681 PF10883.3 ETS83118.1 - 0.12 12.5 0.4 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) GATase PF00117.23 ETS83119.1 - 8.1e-12 44.9 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETS83119.1 - 0.0031 16.9 0.4 0.02 14.3 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 ETS83119.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNF2_N PF00176.18 ETS83120.1 - 9.9e-49 165.7 0.1 1.6e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83120.1 - 1e-10 41.3 0.0 2.8e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS83120.1 - 1.1e-07 31.8 0.1 5.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS83120.1 - 4.8e-06 26.1 0.0 2.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 ETS83120.1 - 8.6e-06 25.6 4.9 2.1e-05 24.4 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS83120.1 - 2.8e-05 23.6 4.2 6.1e-05 22.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS83120.1 - 0.00094 18.9 4.4 0.00094 18.9 3.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 ETS83120.1 - 0.0016 18.1 4.7 0.0039 16.8 3.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 ETS83120.1 - 0.0034 17.0 3.0 0.01 15.4 2.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Spectrin PF00435.16 ETS83120.1 - 0.05 13.8 0.7 0.13 12.5 0.0 2.1 2 0 0 2 2 1 0 Spectrin repeat AAA_22 PF13401.1 ETS83120.1 - 0.073 13.2 0.1 0.33 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain zf-C3HC4_4 PF15227.1 ETS83120.1 - 0.099 12.5 4.7 0.25 11.2 3.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS83120.1 - 0.15 11.8 1.3 0.73 9.5 0.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Pyr_redox_3 PF13738.1 ETS83121.1 - 2.5e-11 44.0 0.0 0.00026 21.1 0.0 3.3 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS83121.1 - 3.8e-07 29.3 0.0 0.0039 16.1 0.0 2.6 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS83121.1 - 1.1e-06 28.7 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS83121.1 - 3.2e-05 22.9 0.2 0.28 10.0 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS83121.1 - 0.0021 17.0 0.2 0.022 13.6 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETS83121.1 - 0.0022 17.0 1.6 0.018 14.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 ETS83121.1 - 0.0028 18.0 1.7 2.3 8.6 0.1 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83121.1 - 0.0031 17.5 0.3 0.074 13.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS83121.1 - 0.0037 17.0 0.0 0.061 13.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1713 PF08213.6 ETS83121.1 - 0.019 14.5 5.3 0.019 14.5 3.7 2.2 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1713) HI0933_like PF03486.9 ETS83121.1 - 0.032 12.7 0.0 0.15 10.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 ETS83121.1 - 0.05 13.7 0.1 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase VirE2 PF07229.7 ETS83121.1 - 0.086 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 VirE2 FAD_binding_2 PF00890.19 ETS83121.1 - 0.17 10.6 2.4 0.12 11.1 0.2 1.8 3 0 0 3 3 3 0 FAD binding domain DUF2196 PF09962.4 ETS83122.1 - 1.1e-21 76.3 2.9 1.7e-21 75.7 2.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-H2C2_5 PF13909.1 ETS83122.1 - 0.079 13.2 0.1 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 ETS83122.1 - 0.11 12.6 0.4 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GATase PF00117.23 ETS83123.1 - 1.5e-32 112.6 0.0 2.4e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 ETS83123.1 - 4.5e-31 106.4 0.0 9.6e-31 105.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 ETS83123.1 - 4.6e-09 35.5 0.0 2.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 ETS83123.1 - 8.4e-07 28.6 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 ETS83123.1 - 0.00081 18.9 0.4 0.0032 17.0 0.0 2.0 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 ETS83123.1 - 0.0027 16.3 0.0 0.0061 15.1 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 ETS83123.1 - 0.011 15.0 0.0 0.085 12.1 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 ETS83123.1 - 0.026 13.9 0.0 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 ETS83123.1 - 0.042 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 ETS83123.1 - 0.05 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 ETS83123.1 - 0.068 12.6 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 PP-loop family NmrA PF05368.8 ETS83124.1 - 8.3e-14 51.4 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS83124.1 - 1.9e-12 47.5 0.3 3.8e-12 46.5 0.1 1.7 2 1 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS83124.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 ETS83124.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 ETS83124.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold peroxidase PF00141.18 ETS83125.1 - 1.8e-23 83.2 0.0 2.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 ETS83125.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Photosystem I psaG / psaK His_Phos_2 PF00328.17 ETS83126.1 - 4.1e-52 177.6 0.0 5e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Inositol_P PF00459.20 ETS83128.1 - 2.9e-63 213.7 0.0 3.5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M50B PF13398.1 ETS83129.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like MFS_1 PF07690.11 ETS83130.1 - 3.1e-33 114.9 21.7 2.4e-26 92.3 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83130.1 - 8.2e-10 37.8 3.5 8.2e-10 37.8 2.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter HTH_23 PF13384.1 ETS83131.1 - 0.015 14.9 0.1 0.044 13.4 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain End3 PF12761.2 ETS83133.1 - 1.7e-72 243.1 1.8 2.4e-72 242.6 1.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 ETS83133.1 - 1.6e-47 159.5 0.0 3.8e-46 155.0 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 ETS83133.1 - 3.1e-06 26.0 0.5 1e-05 24.4 0.4 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 ETS83133.1 - 7.4e-06 25.4 0.2 1.6e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 ETS83133.1 - 0.00011 22.2 0.0 0.002 18.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETS83133.1 - 0.054 12.8 0.4 0.054 12.8 0.3 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 ETS83133.1 - 0.06 13.2 1.0 0.29 11.1 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain Mnd1 PF03962.10 ETS83133.1 - 0.18 11.4 4.4 0.33 10.6 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family DASH_Dad3 PF08656.5 ETS83133.1 - 0.29 10.8 3.9 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 COG2 PF06148.6 ETS83133.1 - 0.82 9.5 4.2 0.81 9.5 0.8 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 ETS83133.1 - 3.3 7.4 9.4 1.5 8.5 0.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MerR-DNA-bind PF09278.6 ETS83133.1 - 5.7 7.4 7.4 2.5 8.5 0.1 3.2 3 0 0 3 3 3 0 MerR, DNA binding Pyr_redox_2 PF07992.9 ETS83134.1 - 1.6e-16 60.8 0.0 3.1e-16 59.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS83134.1 - 8.4e-10 38.9 0.9 5.5e-07 29.8 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS83134.1 - 4.3e-05 23.6 1.7 0.034 14.2 0.2 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS83134.1 - 0.0041 16.0 0.5 0.036 12.9 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 ETS83134.1 - 0.096 11.5 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ACBP PF00887.14 ETS83135.1 - 2.6e-22 78.2 1.4 3e-22 78.0 1.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF3829 PF12889.2 ETS83135.1 - 0.015 14.5 0.9 0.018 14.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1436 PF07262.6 ETS83135.1 - 0.14 11.6 0.6 0.35 10.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1436) Tyr-DNA_phospho PF06087.7 ETS83136.1 - 3e-133 444.7 0.0 3.7e-133 444.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 ETS83136.1 - 0.0032 17.2 0.6 0.79 9.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Thioredoxin PF00085.15 ETS83137.1 - 2.1e-44 149.4 0.2 2.5e-26 91.3 0.0 3.3 3 1 0 3 3 2 2 Thioredoxin Thioredoxin_6 PF13848.1 ETS83137.1 - 8.8e-11 41.9 0.0 0.011 15.5 0.0 3.6 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS83137.1 - 5e-08 32.9 3.1 0.0027 17.7 0.0 3.9 4 1 0 4 4 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS83137.1 - 4.1e-06 26.9 2.4 0.0056 16.8 0.0 4.5 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETS83137.1 - 2.3e-05 24.2 0.4 0.001 19.0 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 ETS83137.1 - 0.00012 21.7 1.2 0.031 13.9 0.0 3.5 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_3 PF13192.1 ETS83137.1 - 0.0016 18.1 0.1 0.088 12.6 0.0 3.3 4 0 0 4 4 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 ETS83137.1 - 0.042 13.8 0.9 0.042 13.8 0.6 4.1 4 0 0 4 4 4 0 Thioredoxin HyaE PF07449.6 ETS83137.1 - 0.066 13.1 0.0 28 4.6 0.0 3.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE 7TM_GPCR_Srh PF10318.4 ETS83137.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Thioredoxin_9 PF14595.1 ETS83137.1 - 0.067 12.7 0.7 5.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin TrbC_Ftype PF09673.5 ETS83137.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TraF PF13728.1 ETS83137.1 - 0.52 9.7 0.0 0.52 9.7 0.0 3.4 4 0 0 4 4 3 0 F plasmid transfer operon protein DUF3742 PF12553.3 ETS83137.1 - 1.3 9.4 4.3 3.2 8.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) Carb_anhydrase PF00194.16 ETS83138.1 - 5.8e-17 61.5 0.4 8.1e-10 38.1 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Chitin_synth_2 PF03142.10 ETS83141.1 - 7.1e-22 77.4 2.7 7.1e-22 77.4 1.9 3.2 2 1 1 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 ETS83141.1 - 7.6e-19 68.4 0.0 1.8e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 ETS83141.1 - 1.6e-17 63.8 6.7 1.6e-17 63.8 4.6 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 ETS83141.1 - 0.022 14.4 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Squash PF00299.13 ETS83141.1 - 0.22 11.3 0.8 0.68 9.7 0.3 2.0 2 0 0 2 2 2 0 Squash family serine protease inhibitor MIF4G PF02854.14 ETS83142.1 - 2.7e-56 190.2 0.0 6.3e-26 91.0 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 ETS83142.1 - 1e-52 178.3 16.0 2.6e-52 177.0 11.1 1.7 1 0 0 1 1 1 1 Up-frameshift suppressor 2 CBP4 PF07960.6 ETS83142.1 - 0.0085 15.7 1.0 0.057 13.0 0.0 2.6 2 0 0 2 2 2 1 CBP4 Mo-co_dimer PF03404.11 ETS83143.1 - 2.3e-57 192.2 0.2 4.4e-57 191.3 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 ETS83143.1 - 3.2e-51 173.0 0.0 5.3e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 ETS83143.1 - 5.8e-30 103.3 0.1 1.6e-29 101.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 ETS83143.1 - 5.6e-24 83.7 0.0 1.1e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 ETS83143.1 - 1.6e-22 80.0 0.0 3.3e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 ETS83143.1 - 0.00093 19.1 0.0 0.096 12.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SecG PF03840.9 ETS83144.1 - 0.02 14.5 0.4 0.02 14.5 0.3 3.3 3 1 1 4 4 4 0 Preprotein translocase SecG subunit MARVEL PF01284.18 ETS83146.1 - 3.5e-05 23.6 20.9 5.3e-05 23.0 14.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain bZIP_2 PF07716.10 ETS83148.1 - 0.00017 21.3 12.9 0.00047 19.9 9.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS83148.1 - 0.0002 21.2 9.7 0.00037 20.3 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF641 PF04859.7 ETS83148.1 - 0.56 9.9 8.8 0.22 11.3 4.1 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETS83148.1 - 0.82 9.2 3.9 1.4 8.4 2.7 1.3 1 0 0 1 1 1 0 IncA protein UIM PF02809.15 ETS83149.1 - 0.12 12.0 1.7 0.69 9.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif GMC_oxred_C PF05199.8 ETS83151.1 - 1.1e-24 87.4 0.4 2.5e-24 86.2 0.3 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS83151.1 - 1.1e-23 83.9 0.0 2.4e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 ETS83151.1 - 4e-12 45.5 11.7 1e-11 44.2 8.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 ETS83151.1 - 1.1e-09 37.6 0.3 0.00035 19.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS83151.1 - 4.2e-06 25.9 0.1 0.00062 18.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS83151.1 - 6.3e-05 22.9 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS83151.1 - 0.0024 16.4 0.0 0.0047 15.4 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS83151.1 - 0.0036 17.2 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS83151.1 - 0.0054 15.8 0.1 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 ETS83151.1 - 0.0056 15.7 0.1 0.0098 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS83151.1 - 0.006 16.6 0.1 0.026 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS83151.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 ETS83151.1 - 0.09 13.1 0.0 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldose_epim PF01263.15 ETS83152.1 - 4.7e-46 157.2 0.4 5.4e-46 157.0 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ABC_membrane PF00664.18 ETS83153.1 - 9.4e-43 146.5 27.7 2.5e-30 105.8 8.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS83153.1 - 1.2e-40 138.9 0.0 8.2e-21 74.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 ETS83153.1 - 4.4e-08 33.3 0.4 0.0003 20.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 ETS83153.1 - 3.3e-07 30.5 0.3 1.5 8.7 0.0 4.3 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 ETS83153.1 - 5.8e-07 28.8 1.5 0.012 14.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SMC_N PF02463.14 ETS83153.1 - 1.7e-06 27.4 2.1 0.037 13.2 0.4 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 ETS83153.1 - 1.1e-05 25.6 1.2 0.044 13.9 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 ETS83153.1 - 2.4e-05 23.8 0.1 0.26 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 ETS83153.1 - 0.00019 20.4 0.1 0.0067 15.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 ETS83153.1 - 0.00079 18.9 0.3 0.25 10.8 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 ETS83153.1 - 0.0045 16.8 0.4 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 ETS83153.1 - 0.0078 16.1 4.9 0.012 15.5 0.2 3.1 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 ETS83153.1 - 0.017 14.9 0.4 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 ETS83153.1 - 0.018 15.5 0.0 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 ETS83153.1 - 0.021 14.7 0.8 1.5 8.7 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 ETS83153.1 - 0.06 12.4 0.1 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS83153.1 - 0.067 12.6 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 ETS83153.1 - 0.11 12.0 0.2 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 ETS83153.1 - 0.12 12.5 0.6 7.2 6.8 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS83153.1 - 0.13 11.6 1.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 ETS83153.1 - 0.15 12.3 1.1 9.2 6.5 0.1 2.6 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 ETS83153.1 - 0.18 11.4 0.0 17 5.0 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 ETS83153.1 - 0.19 11.9 0.0 37 4.5 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Mpv17_PMP22 PF04117.7 ETS83154.1 - 1.1e-15 56.9 1.7 1.1e-15 56.9 1.2 1.9 1 1 0 1 1 1 1 Mpv17 / PMP22 family DUF1961 PF09224.6 ETS83155.1 - 3.7e-82 274.6 0.0 4.8e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) PDZ_1 PF12812.2 ETS83156.1 - 3.1e-56 187.2 0.0 6.7e-34 115.6 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 ETS83156.1 - 4.2e-16 59.0 0.5 1.8e-13 50.5 0.0 2.9 2 1 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.1 ETS83156.1 - 1.2e-14 53.9 1.3 0.00022 21.0 0.0 4.7 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 ETS83156.1 - 6.1e-11 42.3 0.0 0.00094 19.3 0.0 3.9 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 ETS83156.1 - 0.00035 20.2 0.0 0.0011 18.5 0.0 1.9 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 ETS83156.1 - 0.0034 17.1 0.4 0.86 9.4 0.0 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 ETS83156.1 - 0.041 13.2 1.1 0.15 11.4 0.2 2.1 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 ETS83156.1 - 0.13 10.6 0.2 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.11 ETS83156.1 - 0.24 10.6 0.2 0.41 9.9 0.2 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF3592 PF12158.3 ETS83157.1 - 0.15 11.8 1.5 0.24 11.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Toxin_7 PF05980.7 ETS83157.1 - 1.8 8.6 10.5 5.4 7.1 7.3 2.0 1 0 0 1 1 1 0 Toxin 7 Tachystatin_B PF11478.3 ETS83157.1 - 1.8 8.3 7.8 1.1 8.9 3.4 2.1 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B OTU PF02338.14 ETS83158.1 - 0.00017 22.1 0.8 0.0022 18.5 0.1 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease PAP_assoc PF03828.14 ETS83159.1 - 1.7e-17 63.0 0.0 1.4e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 ETS83159.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 ETS83160.1 - 2.9e-12 45.7 54.6 1e-11 43.9 37.9 1.7 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 ETS83161.1 - 1.5e-41 142.0 3.7 1.5e-41 142.0 2.5 2.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4636 PF15468.1 ETS83161.1 - 0.18 11.1 1.5 0.35 10.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) LCM PF04072.9 ETS83162.1 - 2.3e-36 125.0 0.0 2.8e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase UL11 PF11094.3 ETS83163.1 - 0.047 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein p450 PF00067.17 ETS83164.1 - 1.5e-31 109.4 0.0 2.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.9 ETS83166.1 - 2.5e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 ETS83166.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 ETS83166.1 - 0.0037 17.1 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83166.1 - 0.042 13.6 0.0 0.069 12.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 ETS83166.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.7 ETS83166.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.20 ETS83166.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_1_2 PF00155.16 ETS83168.1 - 9.6e-46 156.3 0.0 1.2e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS83168.1 - 0.00085 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase NIR_SIR_ferr PF03460.12 ETS83168.1 - 0.1 12.2 0.0 7.9 6.1 0.0 3.1 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain DinB PF05163.7 ETS83169.1 - 1.6e-22 79.9 0.7 1.9e-22 79.7 0.5 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.2 ETS83169.1 - 7.5e-09 36.0 0.5 8.7e-09 35.7 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily Abhydrolase_3 PF07859.8 ETS83170.1 - 7.3e-49 166.2 0.0 9.6e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS83170.1 - 3.5e-08 32.6 0.7 3.9e-07 29.1 0.5 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 ETS83170.1 - 3.6e-06 26.5 0.1 1.4e-05 24.6 0.0 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 ETS83170.1 - 2.3e-05 23.7 0.0 0.00088 18.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS83170.1 - 4e-05 23.3 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS83170.1 - 0.00053 19.9 0.0 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS83170.1 - 0.046 12.2 0.0 1.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) tRNA-synt_2 PF00152.15 ETS83171.1 - 3.6e-72 242.9 1.8 9.5e-72 241.5 0.4 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 ETS83171.1 - 1.7e-13 50.0 0.1 2.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 ETS83171.1 - 8.4e-05 22.3 0.0 0.00032 20.5 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 ETS83171.1 - 0.01 15.0 0.1 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Aminotran_3 PF00202.16 ETS83172.1 - 1.4e-82 277.2 0.1 1.7e-82 276.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF4388 PF14332.1 ETS83172.1 - 0.077 12.8 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) Exo70 PF03081.10 ETS83173.1 - 1.3e-70 238.1 0.5 8.8e-70 235.3 0.0 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Reo_sigmaC PF04582.7 ETS83173.1 - 0.0019 17.4 5.2 0.02 14.0 0.9 2.5 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Sec8_exocyst PF04048.9 ETS83173.1 - 0.02 14.5 3.2 0.19 11.3 0.2 3.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Nol1_Nop2_Fmu PF01189.12 ETS83174.1 - 5.1e-17 62.1 0.0 2e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 ETS83174.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 ETS83174.1 - 0.065 12.8 0.0 9 5.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain LRAT PF04970.8 ETS83174.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase 2_5_RNA_ligase2 PF13563.1 ETS83175.1 - 5.9e-28 97.5 1.2 9.6e-28 96.8 0.2 1.9 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 ETS83175.1 - 1.1e-26 93.1 0.0 2.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 ETS83175.1 - 1.4e-10 41.1 0.1 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 ETS83175.1 - 2.2e-09 37.5 0.1 5.2e-09 36.3 0.0 1.6 2 0 0 2 2 1 1 Endonuclease/Exonuclease/phosphatase family PAP_RNA-bind PF04926.10 ETS83175.1 - 0.00044 19.8 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap PF03813.9 ETS83175.1 - 0.00063 17.4 0.0 0.00096 16.8 0.0 1.1 1 0 0 1 1 1 1 Nrap protein NTP_transf_2 PF01909.18 ETS83175.1 - 0.0033 17.7 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Myc_N PF01056.13 ETS83175.1 - 0.036 13.2 5.2 0.07 12.2 3.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 ETS83175.1 - 0.05 13.1 6.6 0.11 11.9 4.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 ETS83175.1 - 0.13 11.1 3.4 0.23 10.4 2.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 ETS83175.1 - 0.15 10.5 5.4 0.23 9.8 3.8 1.2 1 0 0 1 1 1 0 Daxx Family TLP-20 PF06088.6 ETS83175.1 - 0.43 10.2 5.7 0.8 9.3 3.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 ETS83175.1 - 0.68 9.1 8.1 1.1 8.4 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 ETS83175.1 - 0.74 7.6 10.9 1.1 7.1 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 ETS83175.1 - 1.5 6.5 3.3 2.3 5.9 2.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2890 PF11081.3 ETS83175.1 - 1.9 8.5 9.2 0.11 12.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 ETS83175.1 - 2.8 7.6 7.5 6.7 6.4 5.2 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit VID27 PF08553.5 ETS83175.1 - 3.9 5.5 9.8 5.9 4.9 6.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Aldo_ket_red PF00248.16 ETS83176.1 - 3.2e-64 216.4 0.0 3.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 ETS83177.1 - 1.3e-37 126.2 8.2 5.7e-10 38.6 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 ETS83177.1 - 9.7e-06 23.9 7.5 0.027 12.5 0.1 4.3 3 2 1 4 4 4 2 Nucleoporin Nup120/160 APG6 PF04111.7 ETS83177.1 - 0.1 11.6 0.4 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETS83177.1 - 0.28 10.7 1.5 0.47 10.0 1.0 1.3 1 0 0 1 1 1 0 IncA protein Suppressor_APC PF11414.3 ETS83177.1 - 0.6 9.9 4.2 2.7 7.8 1.1 2.8 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein CM_2 PF01817.16 ETS83178.1 - 1.1e-08 34.9 0.1 5.1e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 ETS83179.1 - 4.9e-66 221.9 0.1 5.9e-66 221.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Cyclin_N PF00134.18 ETS83180.1 - 8.1e-05 22.1 0.1 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain WD40 PF00400.27 ETS83182.1 - 2e-22 78.1 1.2 8.3e-05 22.3 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ATP_bind_1 PF03029.12 ETS83183.1 - 1.7e-74 250.3 0.0 2.2e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 ETS83183.1 - 0.00096 17.9 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 ETS83183.1 - 0.017 14.2 0.0 0.056 12.5 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 ETS83183.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS83183.1 - 0.059 12.7 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.22 ETS83183.1 - 0.06 12.7 0.0 0.28 10.5 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS83183.1 - 0.11 12.4 0.0 0.5 10.3 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 ETS83183.1 - 0.59 10.9 3.8 6.3 7.6 2.6 2.8 1 1 0 1 1 1 0 AAA domain RNase_P_Rpp14 PF01900.14 ETS83184.1 - 3.5e-34 116.9 0.0 4.6e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family MoCF_biosynth PF00994.19 ETS83185.1 - 3.7e-59 198.2 0.4 1.1e-31 109.1 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 ETS83185.1 - 5.9e-34 116.7 1.8 8.7e-34 116.2 1.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 ETS83185.1 - 8.6e-16 57.6 0.0 2.3e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.16 ETS83187.1 - 3.7e-26 90.8 32.6 1.7e-17 63.0 4.7 3.1 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 ETS83187.1 - 3.7 7.2 8.4 2.1 7.9 2.6 2.7 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L tRNA_bind PF01588.15 ETS83188.1 - 4.5e-23 80.9 0.4 5.8e-22 77.3 0.3 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 ETS83188.1 - 1.8e-06 28.3 0.0 5.4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS83188.1 - 0.061 13.2 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Med3 PF11593.3 ETS83188.1 - 4.2 6.5 6.5 6.1 5.9 4.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNA_pol PF00940.14 ETS83190.1 - 8.6e-163 541.5 0.0 1.1e-162 541.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 ETS83190.1 - 1.2e-69 234.9 0.6 2.6e-69 233.9 0.4 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Oligomerisation PF02410.10 ETS83191.1 - 6.3e-05 22.9 0.0 0.0014 18.6 0.0 2.8 2 1 0 2 2 2 1 Oligomerisation domain mRNA_stabil PF13929.1 ETS83191.1 - 0.019 13.8 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 mRNA stabilisation S1-P1_nuclease PF02265.11 ETS83192.1 - 1.4e-74 250.9 0.2 1.6e-74 250.7 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DHHA2 PF02833.9 ETS83193.1 - 1.7e-25 89.6 0.0 2.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 ETS83193.1 - 1.6e-10 40.8 0.0 3.5e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 DHH family Med3 PF11593.3 ETS83195.1 - 0.63 9.2 17.8 0.73 9.0 12.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP1 PF08601.5 ETS83195.1 - 2.1 7.9 8.6 2.9 7.5 5.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Fungal_trans PF04082.13 ETS83196.1 - 8.7e-07 28.0 0.1 2.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83196.1 - 6.1e-06 26.0 10.2 1.1e-05 25.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AFG1_ATPase PF03969.11 ETS83197.1 - 3.3e-98 328.8 0.0 1.6e-93 313.3 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 ETS83197.1 - 5.3e-05 23.2 4.9 0.021 14.7 0.0 3.8 3 1 0 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.13 ETS83197.1 - 0.00021 21.0 0.2 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.1 ETS83197.1 - 0.0023 18.0 0.0 0.012 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 ETS83197.1 - 0.007 16.5 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 ETS83197.1 - 0.018 15.2 0.2 0.18 11.9 0.0 2.5 2 1 1 3 3 3 0 RNA helicase AAA_5 PF07728.9 ETS83197.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETS83197.1 - 0.035 13.7 0.0 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain DDOST_48kD PF03345.9 ETS83197.1 - 0.045 12.2 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF2036 PF09724.4 ETS83198.1 - 4.2e-07 29.4 0.0 4.9e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) WND PF07861.6 ETS83198.1 - 0.047 12.7 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 WisP family N-Terminal Region RhoGEF PF00621.15 ETS83199.1 - 1.3e-23 83.8 0.3 3e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain DUF4315 PF14193.1 ETS83199.1 - 0.51 10.2 8.1 2.8 7.9 5.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) IBN_N PF03810.14 ETS83200.1 - 4.5e-09 36.0 0.1 3.6e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 ETS83200.1 - 2.4e-07 30.7 0.0 0.0019 18.1 0.0 4.3 4 0 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.10 ETS83200.1 - 0.0012 17.2 0.0 0.021 13.1 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus HEAT PF02985.17 ETS83200.1 - 0.01 15.8 0.8 1e+02 3.4 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HORMA PF02301.13 ETS83201.1 - 4.5e-21 75.3 0.0 5.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.3 ETS83202.1 - 1.7e-30 105.6 0.0 2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 ETS83202.1 - 8.9e-12 45.4 14.9 8.9e-12 45.4 10.3 2.9 3 1 0 3 3 3 1 PI31 proteasome regulator Acetyltransf_7 PF13508.1 ETS83204.1 - 3.3e-05 23.9 0.0 7.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS83204.1 - 0.00096 19.1 0.0 0.0033 17.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS83204.1 - 0.0039 17.0 0.2 0.016 15.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 ETS83205.1 - 8.9e-145 483.0 8.6 1e-144 482.8 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 ETS83206.1 - 6.2e-21 74.7 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 ETS83206.1 - 4.4e-20 71.3 0.3 1e-19 70.1 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 ETS83206.1 - 3.3e-18 65.3 0.0 1e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain Vfa1 PF08432.5 ETS83206.1 - 2 8.4 10.5 3.7 7.5 7.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_61 PF03443.9 ETS83207.1 - 5.6e-47 160.3 0.0 8.9e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.16 ETS83208.1 - 2.1e-24 85.2 0.0 2.4e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 ETS83209.1 - 5.2e-59 199.5 0.6 6e-58 196.0 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83209.1 - 6.4e-22 77.8 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS83209.1 - 0.0051 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS83209.1 - 0.24 10.3 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2413 PF10310.4 ETS83209.1 - 3 6.5 12.2 5.6 5.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) NAD_binding_4 PF07993.7 ETS83210.1 - 1.6e-33 115.6 0.0 2.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS83210.1 - 5.2e-23 81.1 0.0 1e-22 80.1 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 ETS83210.1 - 2.4e-13 50.0 0.0 4.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS83210.1 - 9.3e-05 21.4 0.0 0.012 14.5 0.0 2.6 2 1 0 2 2 2 2 RmlD substrate binding domain PP-binding PF00550.20 ETS83210.1 - 0.0075 16.5 0.2 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 ETS83210.1 - 0.015 15.2 0.0 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 short chain dehydrogenase FAD_binding_3 PF01494.14 ETS83211.1 - 4.2e-12 45.7 0.8 3.7e-11 42.6 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain Cupin_2 PF07883.6 ETS83212.1 - 1.2e-16 59.9 0.1 1.8e-14 52.9 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 ETS83212.1 - 0.00033 20.0 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 ETS83212.1 - 0.046 13.4 0.2 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain MFS_1 PF07690.11 ETS83213.1 - 5.7e-25 87.7 43.3 5.3e-18 64.8 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83213.1 - 1.3e-20 73.4 25.3 7.7e-20 70.8 17.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Ribonuc_L-PSP PF01042.16 ETS83214.1 - 6.3e-19 67.9 0.0 8.5e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.17 ETS83215.1 - 2.4e-34 118.6 0.2 2.7e-34 118.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 ETS83216.1 - 1.5e-16 60.0 0.2 3e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83216.1 - 1.6e-09 37.4 5.9 4e-09 36.2 4.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 ETS83217.1 - 4.3e-137 457.7 0.0 5e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Transferase PF02458.10 ETS83218.1 - 4.8e-18 64.8 0.0 2.9e-14 52.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family MFS_1 PF07690.11 ETS83221.1 - 2.9e-41 141.3 23.4 2.9e-41 141.3 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83221.1 - 9.3e-10 37.6 7.3 9.3e-10 37.6 5.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 ETS83221.1 - 0.0047 15.0 2.9 0.013 13.6 1.8 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 ETS83222.1 - 1.4e-19 70.3 0.0 2.5e-19 69.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 ETS83222.1 - 0.00013 20.8 0.0 0.00084 18.2 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 ETS83222.1 - 0.0022 17.9 2.8 0.0028 17.6 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS83222.1 - 0.015 15.0 1.9 0.17 11.6 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 ETS83222.1 - 0.016 14.1 2.4 0.11 11.3 1.7 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Asparaginase PF00710.15 ETS83222.1 - 0.12 11.2 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Asparaginase Pyr_redox_2 PF07992.9 ETS83222.1 - 0.14 12.0 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS83222.1 - 0.33 9.5 3.9 1.1 7.7 0.9 2.2 1 1 1 2 2 2 0 Tryptophan halogenase SNF2_N PF00176.18 ETS83223.1 - 2.1e-76 256.5 0.2 2.9e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 ETS83223.1 - 8.7e-17 61.0 0.0 1.8e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 ETS83223.1 - 9.6e-12 44.5 4.8 2e-11 43.5 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 ETS83223.1 - 1.2e-10 41.1 0.0 3.6e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 ETS83223.1 - 7.5e-08 32.2 6.6 1.6e-07 31.1 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS83223.1 - 5.8e-07 29.1 4.9 1.1e-06 28.2 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS83223.1 - 1.4e-06 27.8 3.5 3.2e-06 26.7 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS83223.1 - 1.4e-05 24.6 6.6 2.7e-05 23.7 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS83223.1 - 1.4e-05 25.0 1.0 3.4e-05 23.8 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETS83223.1 - 0.0002 21.0 4.5 0.00051 19.7 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS83223.1 - 0.0039 16.9 1.7 0.008 15.9 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger AAA_14 PF13173.1 ETS83223.1 - 0.015 15.2 0.4 4.3 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain zf-Nse PF11789.3 ETS83223.1 - 0.016 14.7 3.3 0.044 13.3 2.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 ETS83223.1 - 0.017 15.0 6.7 0.032 14.0 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Herpes_ori_bp PF02399.10 ETS83223.1 - 0.028 12.3 0.8 0.057 11.3 0.1 1.7 2 0 0 2 2 2 0 Origin of replication binding protein zf-RING_4 PF14570.1 ETS83223.1 - 0.06 12.9 3.6 0.11 12.1 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 ETS83223.1 - 0.17 11.6 2.8 0.59 9.9 1.9 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 ETS83223.1 - 0.26 11.4 2.1 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1272 PF06906.6 ETS83223.1 - 0.5 10.2 2.3 1 9.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 ETS83223.1 - 0.92 9.3 3.2 1.9 8.3 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbons CDO_I PF05995.7 ETS83224.1 - 2.5e-38 130.9 0.0 3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 ETS83224.1 - 0.00016 21.0 0.2 0.00021 20.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) DUF1690 PF07956.6 ETS83225.1 - 0.02 14.8 1.4 0.034 14.1 0.1 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) GAS PF13851.1 ETS83225.1 - 0.023 13.8 0.7 0.049 12.8 0.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2599 PF10783.4 ETS83225.1 - 0.22 12.2 0.2 0.22 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Septin PF00735.13 ETS83226.1 - 8.4e-123 408.8 0.3 8.4e-123 408.8 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 ETS83226.1 - 1.9e-07 31.0 0.0 7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS83226.1 - 7e-05 22.0 0.3 0.00059 19.0 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 ETS83226.1 - 8.3e-05 22.0 1.4 0.0009 18.7 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETS83226.1 - 0.00021 21.5 2.8 0.022 15.0 0.0 3.0 3 0 0 3 3 2 1 ABC transporter AIG1 PF04548.11 ETS83226.1 - 0.00071 18.7 1.4 0.002 17.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 ETS83226.1 - 0.00089 18.7 1.8 0.0026 17.2 1.2 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 ETS83226.1 - 0.0025 17.8 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 ETS83226.1 - 0.003 18.0 0.0 0.013 16.0 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 ETS83226.1 - 0.0038 17.3 0.0 0.034 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS83226.1 - 0.0038 17.0 4.3 0.63 9.8 0.0 3.8 4 0 0 4 4 4 1 Dynamin family Ras PF00071.17 ETS83226.1 - 0.006 15.9 0.2 0.039 13.3 0.0 2.3 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.13 ETS83226.1 - 0.0084 15.5 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 ETS83226.1 - 0.0087 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 ETS83226.1 - 0.033 13.3 4.0 0.062 12.4 2.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.12 ETS83226.1 - 0.044 13.3 0.1 6.5 6.2 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 ETS83226.1 - 0.09 12.9 0.6 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 ETS83226.1 - 0.11 12.0 0.6 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 ETS83226.1 - 0.15 11.8 2.9 0.26 11.0 0.9 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat MobB PF03205.9 ETS83226.1 - 0.26 10.9 0.1 0.26 10.9 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 ETS83226.1 - 0.41 9.2 12.0 0.52 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 ETS83226.1 - 1.7 8.2 7.8 2.9 7.4 5.4 1.3 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.12 ETS83226.1 - 6 6.6 7.2 3.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 ETS83226.1 - 6.8 4.4 8.2 13 3.4 5.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family S4 PF01479.20 ETS83227.1 - 1.5e-14 53.1 0.1 1.5e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 ETS83227.1 - 0.0092 15.5 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Pkinase PF00069.20 ETS83228.1 - 1.4e-06 27.6 0.0 2.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83228.1 - 5.6e-06 25.6 0.0 4.4e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETS83229.1 - 5.8e-46 156.7 0.0 1.3e-45 155.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83229.1 - 3.2e-25 88.6 0.0 6.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS83229.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fungal_trans_2 PF11951.3 ETS83230.1 - 5e-10 38.5 0.5 2.6e-09 36.2 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 ETS83231.1 - 2.4e-110 369.1 23.9 3.9e-110 368.5 16.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83231.1 - 6.1e-26 90.9 43.8 2e-20 72.8 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily La PF05383.12 ETS83232.1 - 8.2e-16 57.5 0.0 1.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 ETS83232.1 - 7.2e-09 35.5 0.1 1.9e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS83232.1 - 4.8e-08 32.5 0.2 9.8e-08 31.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS83232.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_61 PF03443.9 ETS83233.1 - 2.8e-34 118.8 0.0 3.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 ETS83234.1 - 4.2e-17 62.5 3.9 6.6e-17 61.9 2.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83234.1 - 2.4e-07 30.7 1.7 3.2e-07 30.3 1.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83234.1 - 9.4e-07 28.6 5.2 1.1e-06 28.4 2.2 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 ETS83234.1 - 5.2e-06 26.0 0.4 7.1e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS83234.1 - 0.00022 20.2 4.1 0.0045 15.9 2.8 2.2 1 1 0 1 1 1 1 Male sterility protein ATP-grasp_5 PF13549.1 ETS83234.1 - 0.0045 16.2 1.7 0.035 13.3 0.9 2.2 2 1 0 2 2 2 1 ATP-grasp domain NmrA PF05368.8 ETS83234.1 - 0.017 14.3 1.5 0.026 13.7 1.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 ETS83234.1 - 0.53 10.2 8.4 3 7.8 5.8 2.3 1 1 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 ETS83235.1 - 1.9e-40 138.6 24.1 1.9e-40 138.6 16.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83235.1 - 2.5e-12 46.1 7.8 2.5e-12 46.1 5.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS83235.1 - 0.00011 20.5 2.3 0.00017 19.9 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS83235.1 - 0.0037 15.4 1.5 0.011 13.9 1.0 1.7 1 1 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 ETS83235.1 - 0.42 8.6 2.8 0.19 9.7 0.1 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sigma70_ner PF04546.8 ETS83235.1 - 0.92 9.0 2.2 1.4 8.5 1.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Hce2 PF14856.1 ETS83236.1 - 6.8e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 1 1 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Acyl-CoA_dh_1 PF00441.19 ETS83236.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 ETS83237.1 - 4.1e-46 156.9 0.0 6.6e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83237.1 - 9.4e-09 35.0 6.7 2e-08 34.0 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS83238.1 - 3.3e-30 104.8 0.0 1.4e-29 102.7 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83238.1 - 4.7e-09 35.9 7.6 8e-09 35.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 ETS83239.1 - 1.8e-110 361.5 15.0 3e-16 59.5 0.1 12.9 1 1 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83239.1 - 8.9e-76 246.1 45.0 5e-05 22.8 0.0 26.3 26 1 1 27 27 27 16 Ankyrin repeat Ank_4 PF13637.1 ETS83239.1 - 2.8e-67 221.9 16.4 1.7e-07 31.5 0.0 17.4 12 5 7 19 19 19 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83239.1 - 2.7e-60 194.2 21.6 0.00017 21.5 0.0 23.4 24 0 0 24 24 24 15 Ankyrin repeat Ank_5 PF13857.1 ETS83239.1 - 2.5e-41 138.7 37.2 0.00014 22.0 0.1 19.6 12 6 9 21 21 21 10 Ankyrin repeats (many copies) NACHT PF05729.7 ETS83239.1 - 4.4e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 ETS83239.1 - 0.00072 19.7 0.1 0.011 15.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS83239.1 - 0.0021 18.1 0.0 0.008 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS83239.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 ETS83239.1 - 0.12 13.2 0.0 0.47 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS83239.1 - 0.17 11.8 0.0 0.58 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Tannase PF07519.6 ETS83240.1 - 9.9e-82 275.1 7.6 7.2e-81 272.2 5.3 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 ETS83241.1 - 7.6e-46 156.4 32.7 7.6e-46 156.4 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83241.1 - 1.5e-12 46.9 20.8 6.9e-12 44.6 14.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS83241.1 - 2.3e-05 22.7 1.4 4e-05 22.0 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_Mycoplasma PF07672.8 ETS83241.1 - 0.0066 15.6 2.5 0.0066 15.6 1.7 2.5 1 1 1 2 2 2 1 Mycoplasma MFS transporter MFS_3 PF05977.8 ETS83241.1 - 0.05 11.7 6.7 0.11 10.5 4.6 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector Draxin PF15550.1 ETS83241.1 - 0.36 10.4 0.6 0.61 9.6 0.2 1.4 2 0 0 2 2 2 0 Draxin Ank_2 PF12796.2 ETS83242.1 - 1.9e-08 34.5 0.0 2.8e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83242.1 - 1.4e-07 30.9 0.0 0.021 14.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS83242.1 - 2.4e-06 27.6 0.0 0.0007 19.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS83242.1 - 1.5e-05 25.4 0.0 3.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83242.1 - 3.2e-05 23.7 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Epimerase PF01370.16 ETS83243.1 - 1.6e-27 96.4 0.0 3.2e-27 95.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS83243.1 - 4.4e-14 52.8 0.0 1.4e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS83243.1 - 8.6e-11 41.0 0.0 3.6e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS83243.1 - 3.8e-09 35.8 0.0 5e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 ETS83243.1 - 1.5e-08 33.9 0.0 3.8e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS83243.1 - 3.4e-07 30.3 0.1 1.1e-06 28.7 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS83243.1 - 6.1e-06 25.3 0.0 2.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 ETS83243.1 - 0.0014 18.3 0.2 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 KR domain ILVD_EDD PF00920.16 ETS83244.1 - 2e-176 587.4 0.1 2.5e-176 587.1 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family NmrA PF05368.8 ETS83245.1 - 3.1e-33 114.9 0.0 4.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS83245.1 - 4.3e-10 39.8 0.1 5.9e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS83245.1 - 8.9e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS83245.1 - 0.0035 16.0 0.0 0.0054 15.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 ETS83245.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 ETS83245.1 - 0.018 15.0 0.3 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 ETS83245.1 - 0.034 14.5 0.1 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent bZIP_1 PF00170.16 ETS83246.1 - 0.0002 21.2 6.7 0.00036 20.4 4.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_6 PF12697.2 ETS83247.1 - 3.1e-27 95.9 0.1 3.7e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83247.1 - 1.5e-14 54.1 0.0 2.5e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS83247.1 - 5.7e-10 39.1 0.1 1.8e-09 37.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS83247.1 - 2.2e-05 23.7 0.0 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 ETS83247.1 - 3.4e-05 23.2 0.0 0.0025 17.1 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 ETS83247.1 - 0.0019 17.8 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 ETS83247.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 ETS83247.1 - 0.02 14.3 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 ETS83247.1 - 0.049 13.0 0.2 0.67 9.3 0.1 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2048 PF09752.4 ETS83247.1 - 0.15 10.8 0.1 0.51 9.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 ETS83248.1 - 1.3e-32 113.5 0.0 1.6e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83248.1 - 1.1e-17 64.4 0.0 3.5e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS83248.1 - 1.7e-13 50.5 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS83248.1 - 3.5e-05 22.4 0.0 5.4e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.8 ETS83248.1 - 0.0034 16.9 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Pax2_C PF12403.3 ETS83248.1 - 0.052 13.2 0.5 0.099 12.3 0.1 1.6 2 0 0 2 2 2 0 Paired-box protein 2 C terminal Ser_hydrolase PF06821.8 ETS83248.1 - 0.11 12.0 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF1774 PF08611.5 ETS83249.1 - 4.4e-33 113.3 3.6 4.4e-33 113.3 2.5 3.0 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.15 ETS83250.1 - 2.1e-09 37.1 0.6 1.8e-08 34.2 0.4 2.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SPRY PF00622.23 ETS83251.1 - 2.5e-08 34.0 0.0 9.2e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 SPRY domain SMC_Nse1 PF07574.8 ETS83253.1 - 3.5e-33 114.9 0.0 4.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 ETS83253.1 - 2.8e-13 49.6 10.7 4.6e-13 48.9 7.4 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 ETS83253.1 - 1.5 8.7 7.8 1.6 8.5 4.6 1.7 2 0 0 2 2 2 0 Ring finger domain LSM PF01423.17 ETS83256.1 - 4.8e-15 54.8 0.1 6.4e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hairpins PF04877.7 ETS83256.1 - 0.25 10.7 6.4 0.31 10.4 4.5 1.1 1 0 0 1 1 1 0 HrpZ PPR_2 PF13041.1 ETS83257.1 - 1.6e-10 40.7 0.0 0.00032 20.5 0.0 6.8 6 2 2 8 8 8 1 PPR repeat family PPR_3 PF13812.1 ETS83257.1 - 1.9e-07 30.8 2.2 0.031 14.5 0.0 7.0 8 0 0 8 8 8 1 Pentatricopeptide repeat domain Ftsk_gamma PF09397.5 ETS83257.1 - 0.065 12.9 0.2 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Ftsk gamma domain MFS_1 PF07690.11 ETS83258.1 - 7.3e-30 103.8 37.4 7.3e-30 103.8 25.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MRI PF15325.1 ETS83258.1 - 5.4 8.0 6.5 9.2 7.2 4.5 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Ebola_NP PF05505.7 ETS83258.1 - 5.6 4.8 7.3 0.8 7.6 2.5 1.3 2 0 0 2 2 2 0 Ebola nucleoprotein Spc24 PF08286.6 ETS83259.1 - 1.6e-40 137.4 0.8 2.1e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4164 PF13747.1 ETS83259.1 - 0.00086 19.3 9.2 0.0013 18.8 4.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) EAP30 PF04157.11 ETS83259.1 - 0.0056 15.8 3.1 0.0072 15.4 2.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family IncA PF04156.9 ETS83259.1 - 0.0065 16.0 4.1 0.0088 15.6 2.8 1.2 1 0 0 1 1 1 1 IncA protein AAA_27 PF13514.1 ETS83259.1 - 0.012 13.3 6.9 0.014 13.1 4.8 1.1 1 0 0 1 1 1 0 AAA domain Streptin-Immun PF11083.3 ETS83259.1 - 0.016 15.2 0.6 0.067 13.1 0.4 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein APG6 PF04111.7 ETS83259.1 - 0.025 13.6 3.3 0.031 13.3 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ISG65-75 PF11727.3 ETS83259.1 - 0.029 13.4 1.7 0.037 13.0 1.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein MutS_III PF05192.13 ETS83259.1 - 0.029 14.1 3.3 0.033 13.9 2.3 1.1 1 0 0 1 1 1 0 MutS domain III YjcZ PF13990.1 ETS83259.1 - 0.037 13.1 4.2 0.048 12.7 2.9 1.1 1 0 0 1 1 1 0 YjcZ-like protein Reo_sigmaC PF04582.7 ETS83259.1 - 0.037 13.2 3.6 0.046 12.8 2.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Ax_dynein_light PF10211.4 ETS83259.1 - 0.052 13.3 2.9 0.15 11.8 1.8 1.7 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4509 PF14970.1 ETS83259.1 - 0.081 12.5 2.0 0.11 12.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Vps5 PF09325.5 ETS83259.1 - 0.083 12.1 6.9 0.23 10.6 4.7 1.7 1 1 0 1 1 1 0 Vps5 C terminal like DUF724 PF05266.9 ETS83259.1 - 0.2 11.2 2.9 0.32 10.5 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 ETS83259.1 - 0.54 10.2 7.1 9.2 6.2 2.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Viral_P18 PF04521.8 ETS83259.1 - 0.68 9.3 2.9 0.76 9.2 1.2 1.7 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein PEP-utilisers_N PF05524.8 ETS83259.1 - 1.2 8.9 10.1 4.7 7.0 1.0 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal FlgN PF05130.7 ETS83259.1 - 1.4 9.1 9.5 0.13 12.5 1.4 2.1 1 1 1 2 2 2 0 FlgN protein FUSC PF04632.7 ETS83259.1 - 6.4 5.0 8.1 7.3 4.8 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L29 PF00831.18 ETS83259.1 - 6.7 6.4 6.3 11 5.8 0.6 3.0 3 1 0 3 3 3 0 Ribosomal L29 protein Fis1_TPR_C PF14853.1 ETS83260.1 - 1.8e-25 88.5 1.8 3.2e-25 87.7 1.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 ETS83260.1 - 8.5e-18 63.3 0.0 1.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 ETS83260.1 - 0.0037 17.8 0.1 0.0067 17.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83260.1 - 0.004 16.9 1.1 0.0085 15.9 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 ETS83261.1 - 1.7e-15 56.5 6.1 1.7e-15 56.5 4.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS83261.1 - 2.1e-11 43.3 7.6 5.3e-10 38.8 1.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS83261.1 - 1.6e-07 31.2 2.3 1.6e-07 31.2 1.6 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 ETS83261.1 - 7.6e-07 29.0 6.6 7.6e-07 29.0 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS83261.1 - 1.5e-06 27.7 14.9 4.4e-06 26.2 4.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS83261.1 - 7.7e-06 25.5 3.1 7.7e-06 25.5 2.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 ETS83261.1 - 0.0014 18.4 1.7 0.0014 18.4 1.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 ETS83261.1 - 0.0019 17.8 0.2 0.0019 17.8 0.1 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Prok-RING_4 PF14447.1 ETS83261.1 - 0.0023 17.4 1.7 0.0056 16.1 1.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_3 PF14369.1 ETS83261.1 - 0.0039 17.1 7.7 0.007 16.3 2.9 2.4 2 0 0 2 2 2 1 zinc-finger DUF1272 PF06906.6 ETS83261.1 - 0.0096 15.7 7.1 0.13 12.1 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1272) zf-RING_4 PF14570.1 ETS83261.1 - 0.1 12.2 10.4 0.16 11.6 2.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 ETS83261.1 - 0.17 11.7 4.5 0.56 10.0 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Baculo_RING PF05883.6 ETS83261.1 - 0.31 10.8 2.3 0.93 9.3 0.3 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain A2L_zn_ribbon PF08792.5 ETS83261.1 - 0.39 10.2 2.4 0.85 9.1 1.7 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-RING_UBOX PF13445.1 ETS83261.1 - 0.68 9.7 6.5 0.21 11.3 0.3 3.1 3 1 1 4 4 3 0 RING-type zinc-finger Prok-RING_1 PF14446.1 ETS83261.1 - 1 9.1 11.4 6.5 6.5 0.8 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.7 ETS83261.1 - 1.5 8.6 6.6 5.3 6.9 0.1 2.6 1 1 1 2 2 2 0 PhnA Zinc-Ribbon RINGv PF12906.2 ETS83261.1 - 1.6 8.8 16.9 0.039 14.0 5.7 2.2 2 0 0 2 2 2 0 RING-variant domain zf-P11 PF03854.9 ETS83261.1 - 7.2 6.1 11.8 0.049 13.1 2.1 1.8 2 0 0 2 2 2 0 P-11 zinc finger TatD_DNase PF01026.16 ETS83263.1 - 2.3e-30 105.6 0.0 4.4e-30 104.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 ETS83264.1 - 4e-26 91.4 0.6 5.9e-26 90.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83264.1 - 1.5e-07 31.1 9.9 2.7e-07 30.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_reductase PF09338.6 ETS83264.1 - 0.076 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Abhydrolase_6 PF12697.2 ETS83265.1 - 3.1e-10 40.3 2.0 3.1e-10 40.3 1.4 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 ETS83265.1 - 2e-07 29.9 0.0 3.7e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 ETS83265.1 - 5.7e-07 29.3 0.1 4e-06 26.6 0.1 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83265.1 - 0.036 13.6 0.2 9.1 5.7 0.3 2.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 ETS83265.1 - 0.055 12.8 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative esterase MxiH PF09392.5 ETS83266.1 - 0.069 13.7 0.1 1.1 9.8 0.0 2.4 2 1 0 2 2 2 0 Type III secretion needle MxiH like Syntaxin PF00804.20 ETS83266.1 - 0.33 11.1 5.1 4.5 7.4 0.0 3.7 4 0 0 4 4 4 0 Syntaxin Pyridox_oxase_2 PF12766.2 ETS83267.1 - 9e-22 77.2 0.0 2.2e-20 72.7 0.0 2.5 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.12 ETS83268.1 - 7.2e-111 368.5 0.1 3.6e-83 278.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 ETS83268.1 - 2e-45 154.6 0.0 4.2e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 ETS83268.1 - 4.8e-45 152.2 0.0 1.1e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 ETS83268.1 - 4.3e-43 145.9 0.1 9.6e-43 144.8 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 ETS83268.1 - 1.9e-41 141.0 0.1 5.1e-41 139.6 0.0 1.8 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 ETS83268.1 - 1.3e-40 137.9 0.0 1.7e-19 69.9 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 ETS83268.1 - 5.5e-36 124.0 0.1 8.7e-22 77.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 ETS83268.1 - 1.3e-34 119.3 0.0 4.4e-34 117.6 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 ETS83268.1 - 1.3e-23 82.6 0.0 5.6e-23 80.6 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 ETS83268.1 - 5.1e-22 78.0 0.0 1.3e-11 43.8 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ETS83268.1 - 6.7e-16 58.1 0.0 4.1e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS83268.1 - 7.2e-16 58.1 0.5 1.3e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 ETS83268.1 - 3.9e-07 29.7 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 ETS83268.1 - 2.6e-06 27.0 0.1 0.0001 21.8 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 ETS83268.1 - 1.1e-05 25.3 0.2 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 ETS83268.1 - 0.0013 18.1 0.1 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family hGDE_N PF14699.1 ETS83268.1 - 0.065 13.0 0.2 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme Nipped-B_C PF12830.2 ETS83270.1 - 2.4e-44 151.2 0.9 7.3e-43 146.3 0.4 2.9 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 ETS83270.1 - 5.5e-12 45.3 8.2 1.8e-11 43.7 0.6 3.6 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 ETS83270.1 - 4e-05 23.3 1.1 0.017 15.1 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 ETS83270.1 - 0.00024 20.9 0.0 0.01 15.6 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS83270.1 - 0.0025 18.0 0.3 0.54 10.5 0.0 4.1 3 1 2 5 5 5 2 HEAT repeats Phage_30_3 PF08010.6 ETS83270.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 PB1 PF00564.19 ETS83270.1 - 0.073 12.7 0.1 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 PB1 domain TFIIS_C PF01096.13 ETS83271.1 - 7e-16 57.5 2.8 9.7e-16 57.1 1.9 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) tRNA-synt_1f PF01921.13 ETS83271.1 - 0.04 12.5 0.3 0.047 12.3 0.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) Baculo_LEF5_C PF11792.3 ETS83271.1 - 0.072 12.4 0.7 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HEAT_2 PF13646.1 ETS83272.1 - 2.7e-30 104.5 6.3 1e-16 60.9 0.1 3.5 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 ETS83272.1 - 8e-20 69.2 7.0 0.0049 17.2 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 ETS83272.1 - 5.6e-08 33.0 12.2 0.0015 18.9 0.0 5.5 2 2 3 5 5 5 4 HEAT-like repeat HEAT PF02985.17 ETS83272.1 - 1.9e-05 24.3 6.9 0.33 11.1 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat Arm PF00514.18 ETS83272.1 - 0.02 14.7 0.6 8.2 6.4 0.0 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RuvA_C PF07499.8 ETS83272.1 - 0.13 12.4 3.4 7.4 6.8 0.0 3.9 4 0 0 4 4 4 0 RuvA, C-terminal domain PNPOx_C PF10590.4 ETS83273.1 - 2.5e-22 78.1 2.5 2.5e-22 78.1 1.7 2.3 4 0 0 4 4 4 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 ETS83273.1 - 1.8e-19 69.5 0.0 2.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 ETS83273.1 - 0.0019 18.4 0.2 0.0077 16.5 0.0 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DDA1 PF10172.4 ETS83275.1 - 0.0055 16.5 0.9 0.016 15.0 0.3 2.1 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase bZIP_1 PF00170.16 ETS83275.1 - 0.022 14.7 9.8 0.047 13.6 6.8 1.6 1 1 0 1 1 1 0 bZIP transcription factor CENP-Q PF13094.1 ETS83275.1 - 0.13 12.3 5.5 0.3 11.1 3.8 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NDT80_PhoG PF05224.7 ETS83276.1 - 6.6e-42 143.6 0.0 1.4e-41 142.5 0.0 1.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ArfGap PF01412.13 ETS83277.1 - 1.6e-35 121.3 0.2 3.2e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 ETS83278.1 - 5.8e-46 155.7 0.0 7.5e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 ETS83278.1 - 7.7e-07 28.6 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Bromodomain PF00439.20 ETS83279.1 - 2.6e-18 65.7 0.0 5.8e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 ETS83279.1 - 1.4e-06 28.2 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 ETS83280.1 - 2.2e-08 33.9 24.0 3.8e-06 26.9 2.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS83280.1 - 2.7e-06 27.3 12.3 0.0059 16.8 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS83280.1 - 3.6e-06 27.0 19.5 0.0012 19.1 2.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF2225 PF09986.4 ETS83280.1 - 0.38 10.1 0.7 0.8 9.1 0.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) AAA_25 PF13481.1 ETS83281.1 - 1.2e-09 37.9 0.0 3.6e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 ETS83281.1 - 3e-07 29.7 0.0 5.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 ETS83281.1 - 2.3e-06 26.8 0.1 8.4e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.1 ETS83281.1 - 0.00048 19.7 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ETS83281.1 - 0.00053 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaB_C PF03796.10 ETS83281.1 - 0.0017 17.3 0.2 0.0083 15.0 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_10 PF12846.2 ETS83281.1 - 0.011 15.2 0.1 0.02 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 ETS83281.1 - 0.019 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 ETS83281.1 - 0.063 13.4 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.9 ETS83282.1 - 9.8e-42 142.7 0.0 2e-26 92.6 0.0 3.4 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 ETS83282.1 - 0.0045 16.5 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 ETS83282.1 - 0.059 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein IBR PF01485.16 ETS83283.1 - 3.3e-13 49.2 45.9 9.6e-09 34.9 8.4 3.5 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 ETS83283.1 - 0.0012 18.5 8.0 0.0012 18.5 5.5 3.6 3 0 0 3 3 3 1 Ring finger domain Metallophos PF00149.23 ETS83285.1 - 6.5e-37 126.8 0.5 1.4e-29 102.9 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pterin_bind PF00809.17 ETS83286.1 - 7.5e-63 211.6 0.0 1.5e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 ETS83286.1 - 2.4e-40 137.2 0.0 4.8e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 ETS83287.1 - 1.6e-63 214.8 0.1 2.4e-63 214.3 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 ETS83287.1 - 1.6e-05 23.9 0.3 2.3e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS83287.1 - 9.5e-05 21.4 1.9 0.00014 20.8 1.3 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS83287.1 - 0.0019 17.2 0.1 0.0027 16.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase adh_short_C2 PF13561.1 ETS83288.1 - 6.5e-21 75.1 0.0 1.1e-20 74.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS83288.1 - 8.6e-21 74.5 0.8 3e-19 69.5 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83288.1 - 2.6e-13 50.0 0.3 3.6e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 KR domain Shikimate_DH PF01488.15 ETS83288.1 - 0.093 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 ETS83288.1 - 0.11 12.0 0.3 0.28 10.8 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS83288.1 - 0.12 12.3 1.4 0.69 9.8 0.6 2.2 1 1 1 2 2 2 0 NADH(P)-binding MscL PF01741.13 ETS83289.1 - 5.7e-15 55.6 0.2 1.2e-14 54.5 0.1 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 ETS83289.1 - 0.027 14.2 0.7 0.043 13.5 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 ETS83289.1 - 0.15 11.5 0.6 0.24 10.9 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain SUR7 PF06687.7 ETS83290.1 - 1.6e-30 106.3 2.1 1.9e-30 106.0 1.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 ETS83290.1 - 7.6e-05 22.6 6.2 7.6e-05 22.6 4.3 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Hemerythrin PF01814.18 ETS83292.1 - 0.013 15.6 0.1 0.048 13.8 0.0 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Glyco_hydro_76 PF03663.9 ETS83294.1 - 8.4e-127 423.5 13.5 1e-126 423.2 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 ETS83294.1 - 0.00065 18.8 4.2 0.011 14.7 0.2 2.9 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 ETS83295.1 - 1.4e-60 205.1 0.0 1.8e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ETS83295.1 - 0.024 12.9 0.0 0.048 11.9 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 ETS83296.1 - 1.5e-28 99.6 0.0 2.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83296.1 - 5.1e-10 38.8 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS83296.1 - 0.0031 16.5 0.1 0.007 15.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS83296.1 - 0.0069 16.1 3.3 0.07 12.8 1.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS83296.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pro-kuma_activ PF09286.6 ETS83297.1 - 6.8e-48 162.3 0.0 1.3e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS83297.1 - 1e-07 31.4 0.1 1.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family TPR_11 PF13414.1 ETS83298.1 - 5.5e-08 32.3 9.3 5.7e-06 25.8 0.4 3.3 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS83298.1 - 9.6e-05 21.8 5.2 0.43 10.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83298.1 - 0.0014 18.4 7.9 0.37 10.8 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS83298.1 - 0.12 12.4 0.8 0.27 11.4 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 ETS83298.1 - 0.18 12.1 7.5 0.044 14.1 2.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 ETS83298.1 - 0.22 11.3 0.3 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus Macoilin PF09726.4 ETS83299.1 - 1.5 7.0 7.7 2 6.5 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein BAF1_ABF1 PF04684.8 ETS83299.1 - 1.8 7.3 22.7 2.5 6.8 15.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 ETS83299.1 - 7.3 4.6 7.9 9.6 4.3 5.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_topoisoIV PF00521.15 ETS83300.1 - 2.1e-119 399.1 2.4 1.2e-118 396.6 0.1 2.8 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 ETS83300.1 - 5.1e-34 116.9 2.9 1.2e-33 115.7 2.0 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 ETS83300.1 - 1.1e-12 47.7 0.0 4.1e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 ETS83300.1 - 2.7e-09 36.7 0.0 9.4e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 ETS83301.1 - 3.2e-41 140.7 3.6 4.6e-41 140.2 2.5 1.2 1 0 0 1 1 1 1 Reticulon DUF1043 PF06295.7 ETS83301.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Wzy_C PF04932.10 ETS83301.1 - 1 9.0 6.0 0.81 9.4 0.1 2.6 1 1 2 3 3 3 0 O-Antigen ligase RabGAP-TBC PF00566.13 ETS83302.1 - 6.4e-48 163.0 0.0 2.3e-47 161.2 0.0 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prominin PF05478.6 ETS83302.1 - 0.0026 15.4 1.4 0.0026 15.4 1.0 1.5 2 0 0 2 2 2 1 Prominin EMP24_GP25L PF01105.19 ETS83302.1 - 3 7.5 10.5 1.2 8.8 2.0 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 ETS83302.1 - 4.7 7.0 10.7 0.16 11.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SnoaL PF07366.7 ETS83304.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Cys_Met_Meta_PP PF01053.15 ETS83305.1 - 2.8e-138 460.4 0.0 3.3e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 ETS83305.1 - 1.3e-06 27.4 0.1 3.8e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 ETS83305.1 - 6.2e-06 24.7 0.3 1.9e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 ETS83305.1 - 8e-05 21.8 0.2 0.00023 20.3 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 ETS83305.1 - 0.00014 20.6 0.1 0.00024 19.9 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 ETS83305.1 - 0.0013 17.8 0.1 0.0041 16.2 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 ETS83305.1 - 0.023 14.3 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 POTRA domain, ShlB-type Spc97_Spc98 PF04130.8 ETS83306.1 - 3e-127 425.1 1.4 3e-127 425.1 1.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Proteasome PF00227.21 ETS83307.1 - 1.6e-56 190.6 0.1 2e-56 190.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 ETS83307.1 - 1e-13 50.3 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 ETS83307.1 - 0.0031 17.1 0.2 0.089 12.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 ETS83308.1 - 1.3e-15 56.9 0.0 8.4e-09 34.4 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83308.1 - 2.5e-08 33.6 12.0 4.1e-08 32.9 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS83308.1 - 0.1 11.4 2.3 0.06 12.2 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 ETS83309.1 - 4e-57 193.3 0.0 6.5e-55 186.1 0.0 2.6 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 ETS83309.1 - 1.8e-06 28.3 0.0 6.1e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS83309.1 - 0.0027 17.3 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 ETS83309.1 - 0.0051 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS83309.1 - 0.054 13.8 0.0 3.8 7.9 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain Asp_protease PF09668.5 ETS83310.1 - 6.2e-55 184.0 0.3 1.1e-54 183.2 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 ETS83310.1 - 2.2e-12 47.3 0.2 7.3e-12 45.6 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 ETS83310.1 - 5.9e-08 32.4 0.1 3.9e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 ETS83310.1 - 1e-07 31.5 0.0 3.9e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 ETS83310.1 - 2.9e-07 30.4 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 ETS83310.1 - 3.4e-06 26.8 0.3 1.6e-05 24.7 0.0 2.3 3 0 0 3 3 3 1 Retroviral aspartyl protease ubiquitin PF00240.18 ETS83310.1 - 0.00033 19.9 0.0 0.00079 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Fungal_trans PF04082.13 ETS83311.1 - 1.4e-35 122.4 0.0 2.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ycf1 PF05758.7 ETS83311.1 - 0.0032 15.2 0.7 0.004 14.9 0.5 1.1 1 0 0 1 1 1 1 Ycf1 Kei1 PF08552.6 ETS83311.1 - 0.018 14.6 1.2 0.037 13.6 0.8 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Serinc PF03348.10 ETS83311.1 - 0.12 11.0 2.9 0.2 10.3 2.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.3 ETS83311.1 - 0.18 11.1 8.6 0.0092 15.3 1.3 2.0 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 ETS83311.1 - 0.24 11.2 14.6 0.66 9.7 10.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Anoctamin PF04547.7 ETS83311.1 - 0.51 8.9 7.8 0.73 8.4 5.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Peptidase_S49_N PF08496.5 ETS83311.1 - 1.2 8.9 8.9 0.89 9.3 4.9 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4446 PF14584.1 ETS83311.1 - 3.3 7.5 6.7 6.2 6.6 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Hid1 PF12722.2 ETS83311.1 - 4.4 4.8 9.1 8.1 3.9 6.3 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein F-protein PF00469.15 ETS83311.1 - 4.5 6.5 11.5 11 5.2 8.0 1.7 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PigN PF04987.9 ETS83313.1 - 6.9e-163 542.4 29.2 6.9e-163 542.4 20.3 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 ETS83313.1 - 4e-10 39.5 1.1 8.9e-09 35.1 0.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS83313.1 - 2.5e-09 36.7 0.3 2.5e-09 36.7 0.2 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 ETS83313.1 - 0.00094 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.3 ETS83314.1 - 2e-27 95.4 0.2 4.3e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 ATG16 PF08614.6 ETS83314.1 - 0.029 14.2 7.6 0.059 13.1 5.3 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 ETS83314.1 - 0.089 12.6 10.8 0.17 11.7 7.5 1.4 1 0 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 ETS83314.1 - 0.095 11.8 0.3 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 ETS83314.1 - 0.17 10.3 2.7 0.23 9.8 1.9 1.1 1 0 0 1 1 1 0 AAA domain Rootletin PF15035.1 ETS83314.1 - 0.21 11.5 8.6 0.52 10.2 5.9 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.7 ETS83314.1 - 0.23 11.1 12.4 0.48 10.1 8.3 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 ETS83314.1 - 0.46 8.8 8.1 0.7 8.2 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.3 ETS83314.1 - 0.62 9.9 13.3 0.28 10.9 5.4 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETS83314.1 - 1.5 8.3 11.4 20 4.7 7.8 2.0 1 1 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 ETS83314.1 - 3.7 6.8 8.0 4.4 6.5 5.0 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SlyX PF04102.7 ETS83314.1 - 4.5 7.7 8.3 15 6.0 2.6 3.2 2 1 1 3 3 3 0 SlyX Matrilin_ccoil PF10393.4 ETS83314.1 - 6.6 6.1 7.4 47 3.4 1.0 3.6 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Atg14 PF10186.4 ETS83314.1 - 8.5 5.2 9.9 14 4.5 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 ETS83315.1 - 1e-37 129.2 0.0 1.9e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 ETS83315.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS83315.1 - 5.5e-06 26.4 0.9 0.00012 22.1 0.0 2.7 2 1 1 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS83315.1 - 7.4e-06 26.1 0.1 0.00028 21.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS83315.1 - 1.7e-05 24.0 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS83315.1 - 3.7e-05 23.4 0.1 0.00027 20.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS83315.1 - 5.7e-05 23.9 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 ETS83315.1 - 7.7e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 ETS83315.1 - 0.00049 19.5 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 ETS83315.1 - 0.00091 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETS83315.1 - 0.0015 17.7 0.1 0.0032 16.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETS83315.1 - 0.0021 17.1 0.2 0.0039 16.2 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_19 PF13245.1 ETS83315.1 - 0.0022 17.6 0.2 0.0096 15.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 ETS83315.1 - 0.003 16.9 0.3 0.13 11.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 ETS83315.1 - 0.0032 17.5 0.0 0.009 16.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 ETS83315.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.7 ETS83315.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.8 1 1 1 2 2 2 1 NACHT domain Oxidored_nitro PF00148.14 ETS83315.1 - 0.0058 15.3 0.0 0.1 11.2 0.0 2.2 2 0 0 2 2 2 1 Nitrogenase component 1 type Oxidoreductase Sigma54_activat PF00158.21 ETS83315.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 ETS83315.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS83315.1 - 0.019 13.8 0.2 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 ETS83315.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETS83315.1 - 0.021 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 ETS83315.1 - 0.023 14.3 0.1 0.14 11.8 0.0 2.1 2 1 1 3 3 2 0 Archaeal ATPase AAA_18 PF13238.1 ETS83315.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETS83315.1 - 0.042 12.5 0.0 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_11 PF13086.1 ETS83315.1 - 0.058 12.9 0.2 0.098 12.2 0.0 1.4 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 ETS83315.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 1 0 Bacterial dnaA protein ABC_tran PF00005.22 ETS83315.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 ETS83315.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.10 ETS83315.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arv1 PF04161.8 ETS83317.1 - 1.1e-48 165.9 0.0 1.4e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family NAD_binding_2 PF03446.10 ETS83318.1 - 9.7e-15 54.7 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS83318.1 - 4.7e-07 29.8 0.5 6.5e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 ETS83319.1 - 0.0001 22.2 0.0 0.00011 22.1 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 ETS83319.1 - 0.0079 16.2 0.0 0.0087 16.1 0.0 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS83319.1 - 0.014 15.7 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Radical_SAM PF04055.16 ETS83320.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 ETS83320.1 - 4.4e-06 26.8 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 ETS83320.1 - 0.0001 22.2 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1681 PF07933.9 ETS83321.1 - 5.8e-57 191.7 0.0 7.8e-57 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Lon_C PF05362.8 ETS83322.1 - 2.6e-64 216.3 0.0 5.1e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 ETS83322.1 - 3e-33 115.2 0.1 8.5e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 ETS83322.1 - 1.2e-21 77.2 0.0 4.9e-21 75.3 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 ETS83322.1 - 2.2e-07 30.4 0.0 5.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 ETS83322.1 - 7.2e-07 29.2 0.0 3.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETS83322.1 - 7.3e-07 28.9 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS83322.1 - 2.8e-05 24.2 0.0 0.00071 19.7 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 ETS83322.1 - 3e-05 22.8 0.0 6.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 ETS83322.1 - 4.1e-05 24.3 0.0 0.00023 21.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 ETS83322.1 - 6e-05 22.2 0.0 0.00087 18.3 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETS83322.1 - 0.00012 22.1 0.7 0.004 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 ETS83322.1 - 0.0027 17.9 0.5 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS83322.1 - 0.0036 17.1 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 ETS83322.1 - 0.0039 17.0 0.7 0.078 12.8 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase ClpB_D2-small PF10431.4 ETS83322.1 - 0.0039 17.0 4.3 0.0053 16.6 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein TIP49 PF06068.8 ETS83322.1 - 0.0087 14.8 0.2 0.65 8.6 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus DUF258 PF03193.11 ETS83322.1 - 0.024 13.8 0.0 0.071 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 ETS83322.1 - 0.029 13.8 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 ETS83322.1 - 0.029 14.0 0.3 0.095 12.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 ETS83322.1 - 0.04 13.3 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 ETS83322.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 ETS83322.1 - 0.061 12.7 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS83322.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS83322.1 - 0.81 9.9 4.1 0.93 9.7 0.1 2.8 3 0 0 3 3 2 0 ABC transporter Pkinase PF00069.20 ETS83323.1 - 4.6e-10 39.0 0.0 6.2e-09 35.3 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83323.1 - 2.3e-09 36.7 0.0 2.3e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FA_desaturase PF00487.19 ETS83324.1 - 8.6e-17 61.4 10.8 8.6e-17 61.4 7.5 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 ETS83324.1 - 2.2e-16 59.4 0.0 6e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SNF2_N PF00176.18 ETS83325.1 - 9.2e-69 231.5 0.0 1.3e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83325.1 - 3.4e-10 39.6 0.0 8.2e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 ETS83325.1 - 0.00061 19.5 3.1 0.0014 18.4 2.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 ETS83325.1 - 0.0037 16.9 2.8 0.007 16.0 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS83325.1 - 0.042 13.8 2.0 0.096 12.7 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS83325.1 - 0.37 10.4 3.0 1.1 9.0 2.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 ETS83327.1 - 5.8e-31 105.9 0.0 1e-14 53.8 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS83327.1 - 2.4e-24 85.0 0.0 3.8e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS83327.1 - 4e-08 32.9 0.0 0.0065 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 ETS83327.1 - 0.0071 15.9 0.2 11 5.7 0.0 3.3 3 0 0 3 3 3 1 DbpA RNA binding domain API5 PF05918.6 ETS83327.1 - 0.34 9.3 3.1 0.54 8.6 2.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gly-rich_Ago1 PF12764.2 ETS83327.1 - 3.6 8.2 8.4 11 6.6 5.7 2.1 1 1 0 1 1 1 0 Glycine-rich region of argonaut ArfGap PF01412.13 ETS83328.1 - 0.056 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ETF PF01012.16 ETS83329.1 - 6.3e-39 133.3 0.8 7.9e-39 133.0 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CPSase_sm_chain PF00988.17 ETS83330.1 - 5.7e-47 158.4 0.0 1.1e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 ETS83330.1 - 7e-47 159.3 0.0 1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETS83330.1 - 3.5e-06 26.6 0.5 0.00079 18.9 0.3 3.0 1 1 0 1 1 1 1 Peptidase C26 adh_short PF00106.20 ETS83331.1 - 5.2e-62 208.6 6.7 1.5e-31 109.6 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 ETS83331.1 - 3.4e-32 110.4 0.0 9.1e-32 109.0 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.5 ETS83331.1 - 1.5e-30 106.1 1.2 3e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 ETS83331.1 - 6.4e-08 32.4 0.0 1e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Eno-Rase_NADH_b PF12242.3 ETS83331.1 - 0.034 13.9 1.3 0.32 10.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF543 PF04418.7 ETS83331.1 - 2.4 8.1 8.3 6.7 6.7 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 3HCDH_N PF02737.13 ETS83331.1 - 5.9 6.5 7.9 20 4.7 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRP54 PF00448.17 ETS83332.1 - 7.4e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 ETS83332.1 - 5.1e-05 24.0 0.0 0.00018 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 ETS83332.1 - 0.00021 20.1 0.2 0.0004 19.2 0.1 1.3 1 0 0 1 1 1 1 ArgK protein NACHT PF05729.7 ETS83332.1 - 0.00099 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS83332.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 ETS83332.1 - 0.0016 18.7 0.0 0.0047 17.2 0.0 1.9 3 0 0 3 3 1 1 AAA domain KAP_NTPase PF07693.9 ETS83332.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain cobW PF02492.14 ETS83332.1 - 0.0034 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 ETS83332.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_31 PF13614.1 ETS83332.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 ETS83332.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 ETS83332.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 ETS83332.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 ETS83332.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 ETS83332.1 - 0.032 13.2 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase ATP_bind_1 PF03029.12 ETS83332.1 - 0.042 13.3 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 ETS83332.1 - 0.042 14.0 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETS83332.1 - 0.045 14.0 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 ETS83332.1 - 0.045 13.5 0.5 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 ETS83332.1 - 0.072 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 ETS83332.1 - 0.074 12.4 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 ETS83332.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ECM11 PF15463.1 ETS83333.1 - 1.3e-40 138.9 2.4 1.3e-40 138.9 1.6 2.8 2 1 0 2 2 2 1 Extracellular mutant protein 11 Ndc1_Nup PF09531.5 ETS83333.1 - 1.8 6.9 3.9 3.1 6.1 2.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mit_KHE1 PF10173.4 ETS83334.1 - 3.2e-64 216.2 0.2 4.6e-64 215.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Peptidase_C25 PF01364.13 ETS83334.1 - 0.057 12.3 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 Sulfotransfer_3 PF13469.1 ETS83337.1 - 0.0025 18.7 0.0 0.024 15.5 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Methyltransf_23 PF13489.1 ETS83338.1 - 5.2e-21 75.0 0.0 7.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS83338.1 - 3.6e-07 30.5 0.0 4.2e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS83338.1 - 5.3e-07 30.2 0.0 1.1e-05 25.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS83338.1 - 3.1e-06 26.8 0.0 2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS83338.1 - 7.3e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS83338.1 - 0.0039 16.2 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 ETS83338.1 - 0.0041 17.1 0.0 0.009 16.0 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 ETS83338.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 ETS83338.1 - 0.045 12.9 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 ETS83338.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 ETS83338.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2454 PF10521.4 ETS83339.1 - 1.3e-63 214.6 0.0 2e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 ETS83340.1 - 3e-88 295.6 0.0 8.5e-88 294.1 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain DUF1077 PF06417.7 ETS83341.1 - 5.1e-55 184.1 1.7 6.1e-55 183.9 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF2360 PF10152.4 ETS83341.1 - 0.16 12.2 1.6 0.21 11.8 1.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Adaptin_N PF01602.15 ETS83342.1 - 3e-130 435.0 11.8 3.9e-130 434.6 8.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 ETS83342.1 - 1.7e-20 73.5 3.3 3.6e-20 72.5 0.2 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 ETS83342.1 - 9.8e-17 61.0 4.9 7.7e-10 38.9 0.1 4.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 ETS83342.1 - 1.7e-12 46.2 2.6 0.00017 21.3 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 ETS83342.1 - 2.1e-06 28.0 2.7 0.073 13.5 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 ETS83342.1 - 0.00036 20.2 0.6 2 8.2 0.0 4.1 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 ETS83342.1 - 0.0012 18.6 1.0 2.3 8.1 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 ETS83342.1 - 0.0015 17.9 2.7 0.22 10.8 0.1 3.2 3 1 0 3 3 3 2 CLASP N terminal DUF2435 PF10363.4 ETS83342.1 - 0.047 13.5 1.7 1.4 8.8 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DUF4267 PF14087.1 ETS83343.1 - 1.7e-10 40.5 4.1 1.9e-10 40.3 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ACP_syn_III_C PF08541.5 ETS83343.1 - 0.085 12.8 0.4 0.099 12.6 0.3 1.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BAR_2 PF10455.4 ETS83345.1 - 3.2e-60 203.5 0.6 4.5e-60 203.0 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 ETS83345.1 - 2.6e-20 72.9 4.1 3.2e-19 69.3 2.9 2.0 1 1 0 1 1 1 1 BAR domain DUF4360 PF14273.1 ETS83346.1 - 2.1e-18 66.6 0.1 2.4e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) EIF_2_alpha PF07541.7 ETS83347.1 - 2.6e-39 133.4 0.0 5.6e-39 132.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 ETS83347.1 - 2.4e-13 49.9 0.7 5.2e-13 48.8 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 ETS83348.1 - 1.7e-37 127.1 0.0 1.3e-17 63.3 0.0 4.8 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 ETS83348.1 - 2.2e-16 60.4 7.4 2.6e-16 60.1 2.8 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF1625 PF07787.7 ETS83348.1 - 5.2 6.2 11.2 8.7 5.5 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Cupin_8 PF13621.1 ETS83349.1 - 4.5e-30 104.9 0.0 8e-30 104.1 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 ETS83349.1 - 6.9e-11 41.9 0.0 7.7e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 ETS83349.1 - 2.1e-05 24.7 0.0 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 ETS83349.1 - 0.012 15.1 0.0 0.068 12.6 0.0 2.1 2 0 0 2 2 2 0 Cupin domain His_Phos_1 PF00300.17 ETS83350.1 - 3.2e-05 24.0 0.1 8.3e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Z1 PF10593.4 ETS83350.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Z1 domain PolyA_pol PF01743.15 ETS83351.1 - 1.6e-25 89.7 0.3 4.5e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 ETS83351.1 - 2.4e-08 33.3 0.0 7.7e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF3129 PF11327.3 ETS83352.1 - 1.4e-61 207.4 9.1 1.8e-61 207.1 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Ig_2 PF13895.1 ETS83352.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 ETS83352.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Tannase PF07519.6 ETS83354.1 - 0.028 13.1 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Suf PF05843.9 ETS83355.1 - 3.4e-10 40.1 10.4 0.079 12.6 0.0 6.4 4 3 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_12 PF13424.1 ETS83355.1 - 4.4e-10 39.3 0.3 0.56 10.1 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83355.1 - 5.2e-08 32.8 16.8 1.5 9.7 0.0 10.6 11 1 1 12 12 12 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS83355.1 - 1.9e-05 24.2 4.4 2.3 7.9 0.0 6.3 9 0 0 9 9 9 2 TPR repeat TPR_8 PF13181.1 ETS83355.1 - 0.00017 21.1 0.0 0.17 11.7 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 ETS83355.1 - 0.00035 20.3 8.6 2.4 7.9 0.1 6.1 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.1 ETS83355.1 - 0.00057 20.4 11.7 0.05 14.2 0.0 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.5 ETS83355.1 - 0.0052 15.7 9.8 0.27 10.0 0.1 5.2 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference PPR_3 PF13812.1 ETS83355.1 - 0.017 15.3 0.0 0.28 11.5 0.0 3.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_2 PF07719.12 ETS83355.1 - 1.3 9.0 15.3 5.4 7.1 0.1 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 ETS83356.1 - 1e-56 191.5 2.9 1.9e-56 190.7 2.0 1.4 1 1 0 1 1 1 1 ATP synthase subunit D RRM_1 PF00076.17 ETS83358.1 - 9.1e-25 86.0 0.1 1.3e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS83358.1 - 7.4e-17 61.0 0.0 4.7e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS83358.1 - 3e-12 46.2 0.1 7.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 ETS83358.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DSS1_SEM1 PF05160.8 ETS83358.1 - 0.71 9.6 3.1 0.68 9.7 0.5 2.0 2 0 0 2 2 2 0 DSS1/SEM1 family Kei1 PF08552.6 ETS83359.1 - 2.5e-46 157.7 17.3 3.8e-40 137.5 4.2 2.1 1 1 0 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF2975 PF11188.3 ETS83359.1 - 0.27 10.9 5.6 0.74 9.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2474 PF10617.4 ETS83359.1 - 2.5 7.7 5.0 3.1 7.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2474) DUF3149 PF11346.3 ETS83359.1 - 5.2 6.7 9.5 1.6 8.3 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) NIR_SIR PF01077.17 ETS83360.1 - 1.3e-51 174.0 0.3 6.5e-45 152.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 ETS83360.1 - 6.1e-31 105.8 0.0 7.7e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 ETS83360.1 - 3.2e-28 98.5 0.0 7.7e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 ETS83360.1 - 1.3e-08 34.6 0.2 7.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FragX_IP PF05994.6 ETS83361.1 - 0.081 10.6 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Chitin_synth_1 PF01644.12 ETS83362.1 - 3.6e-83 277.2 0.2 6.1e-83 276.5 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 ETS83362.1 - 9.2e-33 111.7 0.1 2.2e-32 110.5 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 ETS83362.1 - 4.5e-21 74.8 4.1 6.4e-19 67.7 0.0 2.4 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS83362.1 - 1.3e-07 31.5 0.3 1.3e-07 31.5 0.2 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS83362.1 - 7.3e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ABC_tran PF00005.22 ETS83363.1 - 1.2e-23 83.9 0.0 5.2e-11 43.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS83363.1 - 2.1e-10 41.0 0.9 0.0038 17.2 0.0 4.0 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 ETS83363.1 - 2.1e-06 27.5 0.0 0.099 12.5 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 ETS83363.1 - 4.6e-06 27.4 0.2 0.19 12.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS83363.1 - 0.00014 22.2 1.1 0.0024 18.2 0.8 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS83363.1 - 0.00055 19.4 0.2 0.09 12.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS83363.1 - 0.0011 19.1 0.0 1.1 9.4 0.0 3.1 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 ETS83363.1 - 0.01 16.3 0.0 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 ETS83363.1 - 0.013 15.3 0.0 7 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 ETS83363.1 - 0.028 13.8 0.0 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 ETS83363.1 - 0.032 13.6 0.0 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 ETS83363.1 - 0.042 13.7 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS83363.1 - 0.053 13.8 0.0 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS83363.1 - 0.074 13.0 0.1 20 5.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 ETS83363.1 - 0.097 12.1 0.0 0.86 9.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 ETS83363.1 - 0.11 12.1 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 ETS83363.1 - 0.13 12.4 0.1 1.5 9.0 0.0 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 ETS83363.1 - 0.19 10.1 0.1 0.31 9.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.6 ETS83364.1 - 9.8e-25 87.0 0.0 1.2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 ETS83365.1 - 1.8e-13 50.3 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETS83365.1 - 0.00011 21.5 0.0 0.00026 20.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 ETS83365.1 - 0.001 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Phage_T7_tail PF03906.9 ETS83365.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.8 1 1 0 1 1 1 0 Phage T7 tail fibre protein Herpes_LMP1 PF05297.6 ETS83365.1 - 6.1 5.6 6.9 7.8 5.3 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.11 ETS83366.1 - 2.2e-29 102.3 47.4 6.5e-29 100.7 29.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS83366.1 - 1.2e-21 76.6 22.7 1.6e-21 76.1 15.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS83367.1 - 1.2e-32 112.9 33.5 1.2e-32 112.9 23.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_7 PF13241.1 ETS83368.1 - 1.8e-27 95.6 0.0 6.4e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 ETS83368.1 - 2.3e-24 84.4 0.0 4.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 ETS83368.1 - 1.4e-14 52.7 0.0 2.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 ETS83368.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FYVE PF01363.16 ETS83369.1 - 2.8e-23 81.5 19.8 7.9e-17 60.9 4.0 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 ETS83369.1 - 0.00027 20.4 0.2 0.00027 20.4 0.2 1.9 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.7 ETS83369.1 - 0.00063 19.8 6.6 0.021 14.9 0.1 2.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 ETS83369.1 - 0.00069 19.4 2.1 0.00069 19.4 1.5 3.5 3 1 1 4 4 4 1 AN1-like Zinc finger Taxilin PF09728.4 ETS83369.1 - 0.0096 15.0 3.6 0.052 12.6 0.1 2.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Seryl_tRNA_N PF02403.17 ETS83369.1 - 0.04 13.9 3.4 0.051 13.5 0.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C2HC5 PF06221.8 ETS83369.1 - 0.45 10.3 15.8 0.81 9.4 0.3 4.1 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type HypA PF01155.14 ETS83369.1 - 0.71 9.5 6.6 3.1 7.5 0.2 3.3 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family TMF_DNA_bd PF12329.3 ETS83369.1 - 1.5 8.7 8.5 2 8.2 0.1 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IBR PF01485.16 ETS83369.1 - 8.1 6.4 14.8 0.39 10.6 0.5 3.4 3 1 0 3 3 3 0 IBR domain DUF3535 PF12054.3 ETS83372.1 - 1.3e-137 459.0 0.2 2.5e-136 454.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 ETS83372.1 - 3.2e-72 242.8 0.0 4.9e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 ETS83372.1 - 6.2e-17 60.1 6.7 0.0081 16.1 0.0 9.1 8 0 0 8 8 8 4 HEAT repeat Helicase_C PF00271.26 ETS83372.1 - 3.8e-14 52.3 0.0 9.2e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 ETS83372.1 - 1.8e-06 28.1 7.8 0.0099 16.1 0.0 6.6 8 2 1 9 9 9 2 HEAT repeats Vac14_Fab1_bd PF12755.2 ETS83372.1 - 3.8e-06 27.1 0.3 1.3 9.4 0.0 3.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETS83372.1 - 1.7e-05 25.1 7.9 8.1 7.0 0.0 8.2 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 ETS83372.1 - 0.0035 16.7 0.1 4.7 6.5 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal SMC_N PF02463.14 ETS83373.1 - 4.7e-62 209.0 14.9 9.7e-62 208.0 10.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 ETS83373.1 - 1.1e-27 96.3 0.0 4.5e-27 94.4 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 ETS83373.1 - 7.4e-15 55.8 21.5 7.4e-15 55.8 14.9 7.4 2 2 3 6 6 6 1 AAA domain AAA_21 PF13304.1 ETS83373.1 - 8.3e-15 55.5 6.5 1.4e-07 31.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 ETS83373.1 - 0.0013 18.2 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 ETS83373.1 - 8.2 5.5 22.9 3.8 6.5 0.2 5.2 3 1 0 5 5 5 0 Reovirus sigma C capsid protein DEAD PF00270.24 ETS83374.1 - 3.7e-42 143.6 0.6 7.5e-42 142.6 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS83374.1 - 1.1e-21 76.4 0.2 8.5e-12 44.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 ETS83374.1 - 3.1e-06 27.1 0.5 1.3e-05 25.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Peptidase_S46 PF10459.4 ETS83374.1 - 0.046 12.1 5.5 0.04 12.3 3.0 1.4 2 0 0 2 2 2 0 Peptidase S46 Phycobilisome PF00502.14 ETS83374.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Phycobilisome protein Exonuc_VII_L PF02601.10 ETS83374.1 - 0.36 9.9 5.5 0.67 9.0 0.1 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit E1-E2_ATPase PF00122.15 ETS83375.1 - 2.4e-67 226.3 2.3 2.4e-67 226.3 1.6 3.0 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 ETS83375.1 - 5.5e-24 85.7 0.0 6.1e-23 82.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS83375.1 - 1.9e-13 51.0 0.0 3.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS83375.1 - 2.6e-09 36.3 0.0 7.8e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS83375.1 - 0.0016 18.1 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF268 PF03269.9 ETS83375.1 - 0.036 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 Hydrolase_like2 PF13246.1 ETS83375.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1900 PF08954.6 ETS83376.1 - 1.9e-48 163.4 0.0 8.6e-48 161.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 ETS83376.1 - 1.9e-35 120.2 0.1 3.9e-35 119.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 ETS83376.1 - 4.3e-26 89.8 0.6 8.5e-08 31.7 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 ETS83376.1 - 0.0014 16.8 0.2 0.2 9.7 0.1 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Gon7 PF08738.5 ETS83376.1 - 0.072 13.0 1.5 0.2 11.6 1.0 1.7 1 0 0 1 1 1 0 Gon7 family SlyX PF04102.7 ETS83376.1 - 3.8 7.9 7.4 2.6 8.4 1.8 2.4 2 0 0 2 2 2 0 SlyX Hamartin PF04388.7 ETS83376.1 - 4.7 5.7 16.0 6.4 5.3 11.1 1.1 1 0 0 1 1 1 0 Hamartin protein SSrecog PF03531.9 ETS83377.1 - 1.4e-73 246.8 0.1 1.5e-72 243.5 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 ETS83377.1 - 6.8e-24 83.6 0.0 6.2e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like LAGLIDADG_2 PF03161.8 ETS83377.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family DUF2201_N PF13203.1 ETS83377.1 - 3.6 6.6 5.8 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain RNA_pol_3_Rpc31 PF11705.3 ETS83377.1 - 4 7.2 20.1 9.8 6.0 13.9 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Anillin PF08174.6 ETS83378.1 - 2.4e-33 115.1 0.1 7.7e-33 113.5 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 ETS83378.1 - 6.6e-09 35.9 0.0 2.2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 PH domain AhpC-TSA_2 PF13911.1 ETS83379.1 - 2.1e-11 43.7 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 ETS83379.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS83379.1 - 0.0013 18.2 0.1 0.078 12.5 0.0 2.1 1 1 1 2 2 2 2 Redoxin Tubulin_3 PF14881.1 ETS83380.1 - 1.1e-79 266.0 0.0 1.8e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 ETS83380.1 - 5.5e-43 145.6 0.0 1.4e-42 144.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 ETS83380.1 - 1.1e-07 31.8 0.0 0.0043 16.9 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain His_biosynth PF00977.16 ETS83381.1 - 9e-33 113.4 0.0 1.1e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 ETS83381.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PcrB family DUF4602 PF15375.1 ETS83382.1 - 0.014 15.4 0.2 0.014 15.4 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4602) eIF-3c_N PF05470.7 ETS83382.1 - 0.016 13.2 6.5 0.017 13.2 4.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Afi1 PF07792.7 ETS83382.1 - 0.05 13.6 3.0 0.14 12.1 2.1 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.7 ETS83382.1 - 0.093 10.6 19.6 0.12 10.2 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETS83382.1 - 0.13 10.7 19.1 0.17 10.3 13.2 1.1 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 ETS83382.1 - 6.5 5.5 13.6 0.32 9.8 5.7 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 ETS83382.1 - 8.3 5.3 32.6 0.39 9.7 14.8 2.3 2 0 0 2 2 2 0 BUD22 STE PF02200.11 ETS83383.1 - 7.6e-62 206.3 0.5 1.5e-61 205.3 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 ETS83383.1 - 0.00028 21.0 3.8 0.00074 19.7 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS83383.1 - 0.00091 19.4 2.3 0.0021 18.2 1.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger Yippee-Mis18 PF03226.9 ETS83384.1 - 1.2e-13 50.8 0.3 1.3e-13 50.8 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrome_C554 PF13435.1 ETS83384.1 - 0.023 14.7 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 ETS83384.1 - 0.032 13.8 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c7 DUF2039 PF10217.4 ETS83384.1 - 0.043 13.8 0.3 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Cytochrom_c3_2 PF14537.1 ETS83384.1 - 0.053 13.8 0.1 0.055 13.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c3 Paired_CXXCH_1 PF09699.5 ETS83384.1 - 0.083 12.4 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) NAD_binding_6 PF08030.7 ETS83385.1 - 1.8e-20 73.4 0.0 1.1e-17 64.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 ETS83385.1 - 1.1e-17 64.2 10.5 1.1e-17 64.2 7.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS83385.1 - 2.1e-16 59.7 0.0 9e-16 57.6 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain SPOUT_MTase PF02590.12 ETS83385.1 - 0.027 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase DUF1206 PF06724.6 ETS83385.1 - 0.057 13.1 0.5 0.057 13.1 0.3 3.7 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1206) CLU PF13236.1 ETS83387.1 - 1e-79 267.0 0.0 2.4e-79 265.8 0.0 1.6 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 ETS83387.1 - 1e-46 158.9 0.6 3.2e-46 157.3 0.0 2.2 3 0 0 3 3 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 ETS83387.1 - 4.5e-25 87.6 0.0 9.2e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 ETS83387.1 - 3.6e-20 71.6 13.4 3.7e-09 36.4 1.3 3.7 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 ETS83387.1 - 5.6e-16 57.8 3.1 7.1e-06 25.7 0.3 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS83387.1 - 2.5e-05 23.8 6.0 0.019 14.6 1.0 3.3 1 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 ETS83387.1 - 0.0024 17.6 4.9 0.062 13.2 0.5 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.7 ETS83387.1 - 0.004 16.9 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.1 ETS83387.1 - 0.037 14.2 1.3 21 5.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS83387.1 - 0.079 13.4 2.3 9.7 6.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS83387.1 - 0.12 11.9 2.1 0.19 11.3 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83387.1 - 0.3 11.8 6.8 0.22 12.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS83387.1 - 2.8 7.9 5.2 2.7 7.9 0.3 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Fork_head PF00250.13 ETS83388.1 - 1.3e-34 118.0 0.4 2.6e-34 117.1 0.3 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 ETS83388.1 - 4e-07 30.0 0.0 8.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-C2H2_4 PF13894.1 ETS83389.1 - 2.4e-07 30.6 11.6 0.00073 19.6 1.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS83389.1 - 2.7e-06 27.3 10.2 0.0057 16.9 1.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS83389.1 - 0.00089 19.4 9.8 0.97 9.8 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 ETS83389.1 - 0.39 10.8 6.6 0.26 11.4 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAT1 PF09770.4 ETS83389.1 - 7 4.7 18.3 9.2 4.3 12.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADH_N PF08240.7 ETS83390.1 - 7.6e-27 93.2 4.7 1.2e-26 92.6 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83390.1 - 5.8e-21 74.4 0.0 8.9e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sen15 PF09631.5 ETS83391.1 - 1e-24 86.6 0.0 1.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 ETS83392.1 - 2.7e-35 119.9 1.2 5e-35 119.1 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.10 ETS83393.1 - 1.1e-10 41.0 1.6 1.1e-10 41.0 0.4 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 ETS83393.1 - 2.4e-05 24.3 26.5 0.0057 16.6 5.2 3.1 2 1 0 2 2 2 2 EamA-like transporter family PDR_assoc PF08370.6 ETS83393.1 - 0.62 9.6 7.0 37 3.9 0.3 3.9 3 0 0 3 3 3 0 Plant PDR ABC transporter associated TrbC PF04956.8 ETS83393.1 - 0.83 9.7 12.4 2.9 7.9 2.9 3.4 3 0 0 3 3 3 0 TrbC/VIRB2 family TPT PF03151.11 ETS83393.1 - 4 7.0 24.9 0.16 11.6 1.5 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family Peptidase_C2 PF00648.16 ETS83394.1 - 1.5e-19 70.0 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 ETS83394.1 - 1.4e-16 60.4 0.0 9.6e-14 51.2 0.0 3.0 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 ETS83394.1 - 0.0003 20.5 1.1 0.00096 18.9 0.7 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain MFS_1 PF07690.11 ETS83395.1 - 1e-38 132.9 33.5 1e-38 132.9 23.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83395.1 - 1.6e-08 33.5 9.6 1.6e-08 33.5 6.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS83395.1 - 0.00097 17.3 0.2 0.00097 17.3 0.2 2.6 4 0 0 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF2178 PF09946.4 ETS83395.1 - 0.0039 16.9 4.1 0.98 9.1 0.1 3.3 3 0 0 3 3 3 2 Predicted membrane protein (DUF2178) Mito_carr PF00153.22 ETS83396.1 - 1.5e-56 188.0 0.9 7.5e-20 70.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.12 ETS83397.1 - 9.9e-23 79.7 9.9 1.5e-22 79.1 6.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.12 ETS83398.1 - 2.6e-10 39.9 0.1 4.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETS83398.1 - 5.6e-06 26.4 0.2 1.1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 ETS83398.1 - 0.17 11.7 0.1 0.48 10.3 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif TPR_11 PF13414.1 ETS83399.1 - 7.4e-19 67.1 28.8 3e-05 23.5 2.2 8.7 9 0 0 9 9 9 5 TPR repeat TPR_2 PF07719.12 ETS83399.1 - 1.3e-09 37.2 33.5 0.016 15.0 0.1 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS83399.1 - 2.3e-07 31.3 49.2 0.0044 17.6 0.1 9.9 6 4 4 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS83399.1 - 2.9e-07 30.1 9.8 1.1 9.6 0.0 7.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83399.1 - 1.2e-06 28.3 37.3 6.8e-05 22.7 4.4 7.8 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETS83399.1 - 1.7e-06 27.3 27.5 0.02 14.4 0.0 9.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS83399.1 - 1.1e-05 24.8 11.4 0.25 11.2 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83399.1 - 2.8e-05 23.5 22.0 0.019 14.7 0.0 6.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 ETS83399.1 - 3.2e-05 23.9 10.0 0.13 12.3 0.1 6.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83399.1 - 6e-05 23.3 39.9 0.67 10.7 0.4 11.6 8 3 4 12 12 12 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS83399.1 - 0.0028 17.9 17.3 1.2 9.6 0.1 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS83399.1 - 0.0073 16.4 2.6 0.0073 16.4 1.8 6.2 7 0 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.1 ETS83399.1 - 0.16 12.2 3.7 3.4 7.8 0.0 3.6 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_19 PF14559.1 ETS83399.1 - 0.3 11.4 30.5 4 7.8 0.2 8.6 6 1 2 8 8 8 0 Tetratricopeptide repeat Cupin_2 PF07883.6 ETS83400.1 - 2.6e-05 23.6 0.0 5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS83400.1 - 0.0095 15.5 0.1 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Transp_cyt_pur PF02133.10 ETS83402.1 - 1e-86 291.2 36.8 1.3e-86 290.9 25.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 ETS83403.1 - 2.1e-40 138.5 45.5 2.7e-36 125.0 32.4 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Polysacc_deac_1 PF01522.16 ETS83404.1 - 9e-10 38.2 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.3 ETS83404.1 - 0.014 14.8 0.1 0.057 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) Fungal_trans PF04082.13 ETS83405.1 - 1.2e-33 116.0 0.4 1.9e-33 115.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMN PF06003.7 ETS83405.1 - 0.046 12.8 0.1 0.95 8.5 0.0 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) MFS_1 PF07690.11 ETS83406.1 - 8e-43 146.4 93.4 2e-35 122.1 44.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83406.1 - 0.063 11.8 40.1 0.075 11.5 10.5 3.0 2 2 0 2 2 2 0 Sugar (and other) transporter Bacteriocin_IId PF09221.5 ETS83407.1 - 0.009 15.9 0.2 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacteriocin class IId cyclical uberolysin-like DUF1049 PF06305.6 ETS83407.1 - 0.016 14.6 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Tubulin PF00091.20 ETS83408.1 - 1e-63 215.0 0.0 2.2e-63 213.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS83408.1 - 8.2e-30 103.4 0.0 1.3e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 ETS83408.1 - 4.5e-06 26.6 0.1 7.7e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 ETS83408.1 - 2.2e-05 23.9 0.2 6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Gly_kinase PF02595.10 ETS83408.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycerate kinase family His_Phos_2 PF00328.17 ETS83409.1 - 1.9e-27 96.5 0.0 2.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 ETS83409.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AAA PF00004.24 ETS83410.1 - 4.5e-06 26.9 0.2 5.6e-05 23.3 0.1 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS83410.1 - 0.00039 21.2 0.0 0.0022 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS83410.1 - 0.004 17.1 0.3 0.03 14.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 ETS83410.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS83410.1 - 0.017 15.2 0.0 0.093 12.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 ETS83410.1 - 0.052 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 ETS83410.1 - 0.053 12.2 0.0 0.34 9.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 ETS83410.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 ETS83410.1 - 0.093 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 ETS83410.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF883 PF05957.8 ETS83412.1 - 0.028 14.7 1.3 0.13 12.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PTCB-BRCT PF12738.2 ETS83413.1 - 2.1e-40 136.4 0.9 1.4e-22 79.2 0.1 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 ETS83413.1 - 1.1e-39 134.4 1.0 2.7e-16 59.4 0.1 5.1 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain DUF4023 PF13215.1 ETS83414.1 - 0.039 13.7 0.5 0.1 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Dsh_C PF12316.3 ETS83414.1 - 8.5 6.4 16.6 2 8.4 6.0 2.3 2 1 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal 2-oxoacid_dh PF00198.18 ETS83416.1 - 1.7e-78 263.0 0.1 2.2e-78 262.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETS83416.1 - 8.8e-19 66.9 0.9 2.4e-18 65.5 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 ETS83416.1 - 9.1e-12 44.4 0.8 2.9e-11 42.7 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 ETS83416.1 - 0.013 15.8 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) TFIIF_alpha PF05793.7 ETS83416.1 - 0.14 10.4 4.1 0.2 9.9 2.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_60s PF00428.14 ETS83416.1 - 0.93 9.9 20.2 0.99 9.8 6.4 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Sec7 PF01369.15 ETS83417.1 - 2.3e-66 223.0 0.8 2.3e-66 223.0 0.6 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 ETS83417.1 - 2.9e-50 169.9 7.3 3.9e-50 169.5 1.2 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 ETS83417.1 - 8e-31 105.4 0.1 8e-31 105.4 0.1 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) p450 PF00067.17 ETS83419.1 - 3.5e-44 151.0 0.0 4.6e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAXNEB PF05625.6 ETS83419.1 - 0.089 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein HsbA PF12296.3 ETS83420.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A p450 PF00067.17 ETS83421.1 - 5.5e-60 203.2 0.0 6.8e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ldh_1_C PF02866.13 ETS83422.1 - 4.6e-43 146.9 0.0 6.7e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 ETS83422.1 - 5.3e-43 146.2 0.1 3.5e-42 143.5 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS83422.1 - 0.00029 19.6 0.0 0.00041 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS83422.1 - 0.033 14.2 0.2 0.084 12.8 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS83422.1 - 0.033 14.5 0.3 0.22 11.8 0.0 2.3 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS83422.1 - 0.068 12.2 0.0 0.59 9.1 0.0 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FliJ PF02050.11 ETS83423.1 - 0.061 13.3 14.0 1.9 8.5 0.6 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein EBV-NA3 PF05009.7 ETS83424.1 - 0.15 11.2 0.1 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Aldedh PF00171.17 ETS83425.1 - 8.5e-184 611.1 1.4 9.6e-184 611.0 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETS83425.1 - 0.0098 15.1 0.0 0.023 13.9 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1487) Acetyltransf_7 PF13508.1 ETS83426.1 - 4.5e-14 52.3 0.0 6.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS83426.1 - 9.7e-13 48.2 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS83426.1 - 1.8e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS83426.1 - 1.1e-05 25.3 0.0 0.00013 21.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 ETS83426.1 - 9.5e-05 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS83426.1 - 0.00036 20.3 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 ETS83426.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 zf-C2HC5 PF06221.8 ETS83427.1 - 6.3e-21 73.8 5.9 9.9e-21 73.2 4.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FYVE PF01363.16 ETS83427.1 - 0.035 13.9 1.2 0.064 13.1 0.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger Aldedh PF00171.17 ETS83428.1 - 1.6e-148 494.8 0.1 2e-148 494.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS83428.1 - 0.0039 15.9 0.0 0.0072 15.0 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS83428.1 - 0.0042 16.3 0.0 0.086 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Romo1 PF10247.4 ETS83428.1 - 0.16 12.1 1.4 0.36 11.0 1.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Methyltransf_25 PF13649.1 ETS83429.1 - 0.00059 20.1 0.0 0.00095 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS83429.1 - 0.00063 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_5 PF00266.14 ETS83430.1 - 2.2e-19 69.4 0.0 3.6e-19 68.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V SUI1 PF01253.17 ETS83431.1 - 6.5e-13 48.2 0.0 2.4e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 ETS83431.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Glyco_hydro_3 PF00933.16 ETS83432.1 - 1.7e-92 309.6 0.1 2.5e-92 309.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS83432.1 - 3.1e-57 193.7 1.1 7.3e-57 192.4 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS83432.1 - 3e-24 84.7 0.0 6.1e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain AA_permease PF00324.16 ETS83433.1 - 3.7e-125 417.9 45.6 4.6e-125 417.6 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS83433.1 - 4.7e-26 91.3 50.8 6.3e-26 90.8 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 ETS83433.1 - 0.0023 17.4 1.3 0.005 16.3 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Glyco_tranf_2_3 PF13641.1 ETS83434.1 - 8e-17 61.7 0.1 1.2e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 ETS83434.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Bac_luciferase PF00296.15 ETS83435.1 - 1.7e-65 221.2 0.2 2.1e-65 220.8 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AMP-binding PF00501.23 ETS83436.1 - 4e-30 104.5 0.0 9.9e-30 103.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS83436.1 - 6.5e-28 97.3 0.0 9.9e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS83436.1 - 1.6e-10 40.8 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS83436.1 - 4.8e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 ETS83436.1 - 4.5e-05 22.4 0.0 0.009 14.9 0.0 2.6 3 0 0 3 3 3 2 RmlD substrate binding domain Ret_tiss PF10044.4 ETS83436.1 - 0.0021 18.5 0.1 0.0093 16.4 0.0 2.1 2 0 0 2 2 2 1 Retinal tissue protein adh_short PF00106.20 ETS83436.1 - 0.0048 16.8 0.6 0.027 14.3 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS83436.1 - 0.18 11.4 0.5 0.63 9.6 0.0 2.2 3 0 0 3 3 3 0 KR domain GYF PF02213.11 ETS83437.1 - 4.8e-19 67.6 0.1 9.7e-19 66.7 0.0 1.5 1 0 0 1 1 1 1 GYF domain TPR_1 PF00515.23 ETS83438.1 - 2.7e-11 42.5 2.1 0.0014 18.1 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83438.1 - 2.9e-11 42.3 5.3 0.0047 16.7 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS83438.1 - 9.3e-11 41.2 3.9 1.8e-08 33.8 0.1 4.3 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 ETS83438.1 - 1.7e-10 41.2 1.0 1.7e-10 41.2 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS83438.1 - 3.1e-09 35.9 0.7 0.042 13.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83438.1 - 3.3e-06 26.9 4.6 0.00019 21.2 0.4 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83438.1 - 5.5e-06 25.7 0.1 0.18 11.6 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS83438.1 - 2.4e-05 24.5 1.9 0.042 14.1 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83438.1 - 0.00019 21.7 2.8 0.0059 17.1 0.5 5.1 6 1 1 7 7 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS83438.1 - 0.003 17.3 0.4 0.011 15.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 ETS83438.1 - 0.0074 16.2 1.9 1.8 8.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS83438.1 - 0.022 15.1 1.9 8.5 7.0 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Caldesmon PF02029.10 ETS83439.1 - 0.02 13.3 5.6 0.028 12.8 3.9 1.1 1 0 0 1 1 1 0 Caldesmon AAR2 PF05282.6 ETS83440.1 - 2.2e-54 184.7 0.0 2.9e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DUF4131 PF13567.1 ETS83441.1 - 3.4 7.0 6.8 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_S9 PF00380.14 ETS83442.1 - 1.5e-39 135.0 0.1 1.7e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 ETS83442.1 - 0.13 9.7 0.0 0.15 9.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein EAP30 PF04157.11 ETS83443.1 - 1.3e-62 210.9 0.0 1.7e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family DEAD PF00270.24 ETS83444.1 - 4.2e-46 156.5 0.0 7.9e-44 149.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS83444.1 - 4.8e-29 100.0 0.0 9.7e-29 99.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS83444.1 - 7.3e-05 22.6 0.0 0.00027 20.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 ETS83444.1 - 0.0027 16.1 0.0 0.12 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 ETS83444.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Glyoxalase_3 PF13468.1 ETS83444.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain DUF2443 PF10398.4 ETS83444.1 - 0.055 13.2 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Desmo_N PF06771.6 ETS83444.1 - 0.073 13.0 0.1 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus POTRA_2 PF08479.6 ETS83444.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF2119 PF09892.4 ETS83444.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Phos_pyr_kin PF08543.7 ETS83445.1 - 1.2e-85 286.5 0.3 1.8e-85 286.0 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 ETS83445.1 - 4.3e-48 163.8 0.0 6.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 ETS83445.1 - 5.2e-11 42.2 0.0 8.7e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 ETS83445.1 - 0.035 13.2 2.3 1.3 8.1 0.0 2.6 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family TPR_11 PF13414.1 ETS83446.1 - 2.6e-20 71.8 10.3 3.2e-10 39.4 0.1 3.1 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 ETS83446.1 - 7.6e-18 63.2 8.4 2.8e-08 32.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83446.1 - 7.7e-17 59.7 7.0 2.8e-06 26.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS83446.1 - 1.7e-10 39.8 5.4 1.4e-05 24.5 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83446.1 - 4.2e-09 36.2 2.7 9.7e-06 25.4 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS83446.1 - 1.6e-08 34.4 0.7 0.03 14.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83446.1 - 3.5e-08 32.6 0.2 2.4e-06 26.8 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.19 ETS83446.1 - 1.8e-07 30.7 0.4 3.3e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 ETS83446.1 - 3.8e-06 26.6 0.8 0.05 13.8 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS83446.1 - 1e-05 26.0 4.7 0.0027 18.3 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS83446.1 - 6.4e-05 22.7 0.5 0.28 11.0 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83446.1 - 0.001 19.5 0.3 0.03 14.9 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS83446.1 - 0.012 15.7 3.4 0.044 13.9 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 ETS83446.1 - 0.042 13.6 0.2 0.14 12.0 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 ETS83446.1 - 0.048 14.0 0.6 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS83446.1 - 0.082 13.3 0.0 28 5.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.4 ETS83446.1 - 0.088 11.3 0.1 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Sod_Cu PF00080.15 ETS83447.1 - 7.8e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 ETS83447.1 - 2.8e-11 43.3 0.1 5.2e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_L13 PF00572.13 ETS83448.1 - 3.1e-38 130.7 0.0 4.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ank_2 PF12796.2 ETS83450.1 - 4.3e-40 135.9 5.7 2.9e-12 46.7 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS83450.1 - 8.4e-38 127.5 7.8 3.1e-08 33.6 0.0 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 ETS83450.1 - 1.6e-36 122.2 12.4 8.6e-08 31.6 0.0 8.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 ETS83450.1 - 5.8e-27 93.5 9.7 6.8e-08 32.8 0.0 7.5 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83450.1 - 1.5e-26 89.7 5.4 2.3e-05 24.1 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Uricase PF01014.13 ETS83451.1 - 8.1e-77 255.9 1.2 9.5e-39 132.6 0.0 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 ETS83452.1 - 2.2e-139 464.1 0.8 4.8e-138 459.7 0.4 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 ETS83452.1 - 7e-87 290.1 0.0 1.9e-85 285.4 0.0 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 ETS83452.1 - 4.4e-41 139.4 0.1 4.3e-40 136.2 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 ETS83452.1 - 8.1e-28 96.1 0.1 1.4e-26 92.2 0.1 3.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 ETS83452.1 - 1.2e-11 44.1 6.5 3.8e-11 42.5 4.5 1.9 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 ETS83452.1 - 0.00023 21.1 5.9 0.00073 19.5 4.1 1.8 1 0 0 1 1 1 1 Up-regulated During Septation YPEB PF14620.1 ETS83452.1 - 0.19 10.7 1.9 0.38 9.7 1.3 1.4 1 0 0 1 1 1 0 YpeB sporulation IncA PF04156.9 ETS83452.1 - 0.37 10.3 5.8 0.8 9.2 4.0 1.5 1 0 0 1 1 1 0 IncA protein RIX1 PF08167.7 ETS83453.1 - 3.2e-41 140.7 1.0 3.2e-41 140.7 0.7 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.1 ETS83454.1 - 8.8e-09 35.2 5.5 0.3 11.8 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83454.1 - 6.6e-06 25.9 4.7 3 7.8 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS83454.1 - 8.7e-06 25.5 0.4 0.13 12.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS83454.1 - 1.3e-05 25.4 3.5 0.048 14.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83454.1 - 1.3e-05 24.6 0.4 1.2 9.0 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS83454.1 - 2e-05 24.1 10.1 0.18 11.4 0.1 6.0 8 0 0 8 8 8 2 TPR repeat TPR_8 PF13181.1 ETS83454.1 - 3.6e-05 23.2 4.0 0.00032 20.2 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS83454.1 - 0.00066 19.1 6.8 0.47 10.1 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83454.1 - 0.0009 18.9 19.2 0.2 11.6 0.1 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETS83454.1 - 0.0014 18.7 0.0 13 5.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS83454.1 - 0.062 13.9 15.1 2.4 8.9 0.5 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS83454.1 - 6.4 7.4 7.4 1.5 9.4 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS83455.1 - 7.1e-37 126.9 24.3 1.1e-36 126.2 16.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83455.1 - 5.2e-06 25.3 17.4 9.7e-06 24.4 12.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter SGL PF08450.7 ETS83456.1 - 1.4e-59 201.4 0.0 1.7e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Sin_N PF04801.8 ETS83456.1 - 0.0013 17.6 0.6 0.0018 17.1 0.4 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region YMF19 PF02326.10 ETS83456.1 - 0.16 12.5 0.3 0.27 11.8 0.2 1.3 1 0 0 1 1 1 0 Plant ATP synthase F0 TAF4 PF05236.9 ETS83456.1 - 0.41 9.8 5.7 0.61 9.3 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family bZIP_2 PF07716.10 ETS83457.1 - 8.8e-05 22.2 11.4 0.00014 21.5 7.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS83457.1 - 0.0014 18.5 12.1 0.0024 17.8 8.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor SYF2 PF08231.7 ETS83457.1 - 0.0069 16.5 1.6 0.012 15.7 1.1 1.2 1 0 0 1 1 1 1 SYF2 splicing factor TMF_DNA_bd PF12329.3 ETS83457.1 - 0.021 14.6 2.8 0.034 13.9 1.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding EMP24_GP25L PF01105.19 ETS83457.1 - 0.14 11.8 0.7 0.21 11.2 0.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 ETS83457.1 - 0.86 9.1 9.3 0.87 9.1 5.3 1.7 1 1 1 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.12 ETS83457.1 - 5.8 7.2 13.8 12 6.2 9.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.4 ETS83457.1 - 7.5 5.4 6.9 10 4.9 4.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 adh_short PF00106.20 ETS83459.1 - 1.2e-09 38.3 6.8 2.2e-09 37.4 3.4 2.1 1 1 1 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 ETS83459.1 - 1.1e-05 24.8 0.5 1.8e-05 24.1 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS83459.1 - 1.3e-05 25.2 5.5 6.4e-05 23.0 3.8 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS83459.1 - 3.5e-05 23.5 7.9 4.4e-05 23.2 0.3 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS83459.1 - 0.004 16.6 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 ETS83459.1 - 0.006 16.9 0.1 0.017 15.4 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 ETS83459.1 - 0.03 14.0 0.4 0.064 13.0 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4167 PF13763.1 ETS83459.1 - 0.13 12.3 0.6 0.23 11.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) AlaDh_PNT_C PF01262.16 ETS83459.1 - 3.2 7.3 5.3 0.88 9.1 0.3 2.2 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CorA PF01544.13 ETS83462.1 - 1.3e-09 37.5 0.0 2.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HET PF06985.6 ETS83463.1 - 1.4e-11 44.7 0.0 5.8e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 ETS83463.1 - 2.3e-08 33.2 0.0 4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 ETS83463.1 - 0.00059 19.7 2.0 0.0017 18.2 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 ETS83463.1 - 0.0085 16.2 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS83463.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS83463.1 - 0.055 13.4 1.3 0.14 12.1 0.3 2.3 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 ETS83463.1 - 0.059 12.7 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_19 PF14559.1 ETS83463.1 - 0.081 13.2 2.1 0.74 10.1 0.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat PTB PF08416.8 ETS83463.1 - 0.09 12.6 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Apc3 PF12895.2 ETS83463.1 - 0.11 12.6 1.6 0.24 11.5 0.1 2.4 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 ETS83463.1 - 0.27 11.1 0.8 1.3 8.9 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 ETS83464.1 - 5.8e-29 100.2 0.0 9.1e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 ETS83464.1 - 1.1e-09 38.1 40.7 4.2e-07 29.8 12.3 4.1 3 1 1 4 4 4 2 Chitin recognition protein SOG2 PF10428.4 ETS83464.1 - 5.1 5.6 9.8 7.3 5.1 6.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2360 PF10152.4 ETS83464.1 - 8.5 6.6 7.1 3.2e+02 1.5 4.6 3.1 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) ApbA PF02558.11 ETS83465.1 - 2.9e-29 101.4 0.0 4.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 ETS83465.1 - 2.1e-27 95.6 0.0 3.5e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Saccharop_dh PF03435.13 ETS83465.1 - 0.03 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 ETS83465.1 - 0.063 13.7 0.0 0.57 10.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF4112 PF13430.1 ETS83466.1 - 1e-30 105.7 0.4 1.4e-30 105.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.16 ETS83467.1 - 1.7e-121 404.5 2.1 2e-121 404.3 1.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 ETS83468.1 - 9.8e-26 89.3 0.0 1.2e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.27 ETS83469.1 - 1.3e-17 62.8 0.2 6.6e-09 35.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 ETS83469.1 - 0.089 10.9 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ribosomal_L19 PF01245.15 ETS83470.1 - 1.1e-17 63.8 0.0 1.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.20 ETS83472.1 - 1.7e-57 194.9 0.1 2.1e-57 194.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.20 ETS83473.1 - 1.8e-07 30.7 4.0 1.8e-07 30.7 2.7 5.2 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS83473.1 - 3e-07 30.1 5.1 3e-07 30.1 3.5 4.6 4 2 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.1 ETS83473.1 - 8.7e-07 28.6 0.3 8.7e-07 28.6 0.2 3.8 5 1 0 5 5 5 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 ETS83473.1 - 2.4e-06 27.4 4.6 2.4e-06 27.4 3.2 5.0 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.23 ETS83473.1 - 1.6e-05 24.2 0.0 3.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS83473.1 - 3.2e-05 23.4 2.1 0.00013 21.5 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_5 PF14634.1 ETS83473.1 - 4.7e-05 23.0 2.8 4.7e-05 23.0 1.9 5.4 4 3 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS83473.1 - 0.0016 18.2 4.5 0.0016 18.2 3.1 5.1 5 2 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS83473.1 - 0.0018 17.9 1.2 0.0018 17.9 0.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger SH3_2 PF07653.12 ETS83473.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ECH PF00378.15 ETS83474.1 - 8.2e-69 231.4 0.1 1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS83474.1 - 0.0029 17.4 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 Rer1 PF03248.8 ETS83475.1 - 2.3e-81 271.5 5.1 2.7e-81 271.3 3.5 1.0 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.19 ETS83475.1 - 3.8 6.8 10.0 8.2 5.7 2.1 2.0 2 0 0 2 2 2 0 Fatty acid desaturase Paf1 PF03985.8 ETS83476.1 - 4.9e-55 187.0 7.6 3.5e-54 184.1 5.3 1.9 1 1 0 1 1 1 1 Paf1 TrkH PF02386.11 ETS83477.1 - 1.3e-115 385.7 25.0 6.4e-114 380.2 11.1 2.1 2 0 0 2 2 2 2 Cation transport protein Helicase_C_3 PF13625.1 ETS83478.1 - 3.3e-27 94.7 0.0 5.5e-26 90.8 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS83478.1 - 1.5e-13 51.0 0.0 3.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS83478.1 - 1.7e-10 40.2 0.1 3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83478.1 - 3.4e-09 36.4 0.0 1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SYCE1 PF15233.1 ETS83478.1 - 0.017 15.0 0.3 0.043 13.7 0.2 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 TruD PF01142.13 ETS83479.1 - 9.1e-54 182.5 1.9 1.5e-47 162.1 0.0 4.1 3 2 1 4 4 4 4 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.20 ETS83480.1 - 7e-64 215.4 0.0 1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83480.1 - 4.1e-45 153.8 0.0 6.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS83480.1 - 2.6e-08 33.1 0.0 1.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 ETS83480.1 - 0.018 14.0 0.0 0.045 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cobl PF09469.5 ETS83480.1 - 0.3 11.1 0.1 0.67 9.9 0.1 1.6 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Cyt-b5 PF00173.23 ETS83483.1 - 8.4e-31 105.5 5.9 3.3e-14 52.4 0.0 5.4 4 1 1 5 5 5 4 Cytochrome b5-like Heme/Steroid binding domain Cellulase PF00150.13 ETS83484.1 - 8.9e-12 44.7 2.3 1.9e-07 30.5 0.3 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 ETS83485.1 - 1.5e-45 152.6 32.0 4.3e-06 26.2 0.0 12.5 12 0 0 12 12 12 10 TPR repeat TPR_16 PF13432.1 ETS83485.1 - 2.5e-31 107.6 27.0 0.0002 21.9 0.1 12.3 10 1 2 12 12 12 6 Tetratricopeptide repeat TPR_2 PF07719.12 ETS83485.1 - 4.6e-27 91.7 42.1 0.0059 16.4 0.2 16.0 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_1 PF00515.23 ETS83485.1 - 3e-23 80.4 29.9 0.0024 17.3 0.0 14.6 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83485.1 - 3.2e-22 78.2 43.7 0.00077 19.3 0.0 13.1 9 5 3 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETS83485.1 - 1.3e-21 75.1 31.0 0.0049 17.3 0.1 14.8 13 3 3 16 16 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 ETS83485.1 - 2.1e-21 74.2 15.8 0.061 13.5 0.0 14.1 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS83485.1 - 4.3e-21 75.0 19.0 0.0001 22.5 0.3 10.1 8 4 3 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 ETS83485.1 - 1.9e-13 49.1 28.6 0.16 11.8 0.0 13.4 13 1 1 14 14 14 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83485.1 - 1.3e-11 43.3 23.3 0.26 11.1 0.1 12.9 15 1 0 15 15 13 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS83485.1 - 5e-09 35.8 3.3 0.07 13.0 0.4 6.6 6 1 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS83485.1 - 4.2e-07 29.9 20.8 0.054 13.6 0.0 7.9 7 2 2 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS83485.1 - 2.6e-06 27.5 28.0 0.2 12.1 0.0 12.4 15 0 0 15 15 11 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETS83485.1 - 0.00027 20.9 11.6 6.2 7.0 0.0 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat HemY_N PF07219.8 ETS83485.1 - 0.00035 20.1 0.1 0.88 9.1 0.0 4.5 3 1 1 4 4 4 1 HemY protein N-terminus Coatomer_WDAD PF04053.9 ETS83485.1 - 0.0034 16.2 0.2 0.011 14.5 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region TPR_10 PF13374.1 ETS83485.1 - 0.35 10.8 12.2 11 6.1 0.1 7.5 8 0 0 8 8 6 0 Tetratricopeptide repeat Tannase PF07519.6 ETS83486.1 - 9.4e-106 354.3 0.7 1.5e-105 353.6 0.5 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 ETS83486.1 - 1.2e-06 27.9 0.4 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS83486.1 - 5.9e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83486.1 - 7.1e-05 22.5 0.0 0.0011 18.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83486.1 - 0.00021 20.9 0.0 0.00048 19.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold NAD_binding_10 PF13460.1 ETS83487.1 - 3.8e-10 40.0 0.0 5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS83487.1 - 0.00056 19.2 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Lipase_GDSL_2 PF13472.1 ETS83488.1 - 0.00061 19.9 1.0 0.006 16.7 0.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS83488.1 - 0.0013 18.5 0.8 0.0029 17.4 0.6 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3353 PF11833.3 ETS83492.1 - 0.1 12.0 1.3 0.16 11.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) adh_short PF00106.20 ETS83494.1 - 1.2e-24 87.1 3.6 1.6e-24 86.7 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83494.1 - 2.5e-10 40.2 0.6 3.6e-10 39.7 0.4 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS83494.1 - 6.4e-09 35.9 0.1 8.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 ETS83494.1 - 0.0031 16.4 0.1 0.0043 16.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS83494.1 - 0.015 14.7 0.1 0.05 13.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4263 PF14082.1 ETS83494.1 - 0.022 14.6 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) NAD_binding_10 PF13460.1 ETS83494.1 - 0.086 12.8 2.1 0.14 12.1 1.4 1.5 1 1 0 1 1 1 0 NADH(P)-binding zf-MYND PF01753.13 ETS83495.1 - 3.1e-10 39.7 14.6 5.4e-10 38.9 10.1 1.4 1 0 0 1 1 1 1 MYND finger FAD_binding_4 PF01565.18 ETS83497.1 - 4.3e-24 84.5 1.1 7.9e-24 83.7 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS83497.1 - 0.00021 21.1 1.8 0.00031 20.5 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like HhH-GPD PF00730.20 ETS83498.1 - 0.027 14.7 0.2 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein DUF3287 PF11690.3 ETS83498.1 - 1.7 8.7 6.1 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) AAA PF00004.24 ETS83499.1 - 5.2e-16 59.0 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS83499.1 - 0.00014 21.9 0.7 0.00036 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS83499.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS83499.1 - 0.0062 16.6 0.1 0.037 14.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain Pkinase PF00069.20 ETS83500.1 - 3.6e-71 239.3 0.0 4.8e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83500.1 - 1.4e-33 116.0 0.0 1.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETS83500.1 - 8.4e-11 42.2 2.2 2.6e-10 40.6 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS83500.1 - 0.0015 17.5 0.0 0.0032 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Peptidase_S9 PF00326.16 ETS83501.1 - 6.6e-40 136.6 0.7 1.3e-39 135.6 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS83501.1 - 3.2e-05 23.7 0.1 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DPPIV_N PF00930.16 ETS83501.1 - 0.0003 19.4 1.2 0.0045 15.6 0.1 2.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 ETS83501.1 - 0.0099 15.5 1.8 2.6 7.7 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF2920 PF11144.3 ETS83501.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.11 ETS83502.1 - 0.00042 19.1 43.7 0.00042 19.1 30.3 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.6 ETS83503.1 - 4.4e-100 335.6 4.1 2.8e-99 332.9 2.9 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS83503.1 - 0.0016 18.3 0.0 0.03 14.2 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83503.1 - 0.017 14.8 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sulfatase PF00884.18 ETS83504.1 - 2.3e-62 210.9 1.0 3.2e-62 210.4 0.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS83504.1 - 2.1e-05 24.0 0.1 0.00014 21.3 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 ETS83504.1 - 0.047 12.1 0.0 0.084 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF946 PF06101.6 ETS83506.1 - 1.7e-10 39.5 1.1 1.9e-10 39.3 0.2 1.4 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) F-box-like PF12937.2 ETS83506.1 - 1e-06 28.3 0.0 3e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS83506.1 - 0.00012 21.6 0.1 0.00046 19.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain Amidase PF01425.16 ETS83507.1 - 1.3e-32 113.2 4.2 1.9e-32 112.6 2.9 1.2 1 0 0 1 1 1 1 Amidase COesterase PF00135.23 ETS83509.1 - 5.6e-71 239.8 1.4 2.2e-66 224.6 1.5 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS83509.1 - 8.7e-07 28.7 0.1 1.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS83509.1 - 0.0027 17.4 0.1 0.007 16.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family 4HBT_3 PF13622.1 ETS83510.1 - 1.4e-37 129.8 0.3 1.7e-37 129.5 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.6 ETS83511.1 - 3.4e-36 124.4 1.2 8e-36 123.2 0.1 2.1 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Lipocalin_2 PF08212.7 ETS83513.1 - 1.1e-21 77.0 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain UPF0121 PF03661.8 ETS83514.1 - 2.1e-09 36.9 1.6 2.8e-09 36.5 1.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.15 ETS83515.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS83515.1 - 0.00043 19.6 0.0 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETS83515.1 - 0.002 18.3 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PhyH PF05721.8 ETS83516.1 - 8.3e-08 32.5 0.0 3.6e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 ETS83516.1 - 0.013 15.7 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF3712 PF12505.3 ETS83517.1 - 3.9e-24 85.0 2.3 6.2e-24 84.4 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 ETS83517.1 - 0.042 14.2 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein Ret_tiss PF10044.4 ETS83518.1 - 6.2e-07 29.8 5.3 0.27 11.8 0.0 7.9 3 1 8 11 11 11 1 Retinal tissue protein EIID-AGA PF03613.9 ETS83518.1 - 0.034 13.0 8.5 8.5 5.2 0.1 5.9 2 2 2 4 4 4 0 PTS system mannose/fructose/sorbose family IID component NUC130_3NT PF08158.7 ETS83518.1 - 0.34 11.2 13.1 44 4.4 0.1 7.6 8 0 0 8 8 8 0 NUC130/3NT domain GAF_3 PF13492.1 ETS83518.1 - 0.34 11.0 5.6 61 3.7 0.1 4.8 3 3 0 4 4 4 0 GAF domain DREPP PF05558.7 ETS83518.1 - 0.41 10.4 0.0 2.3e+02 1.4 0.0 3.8 4 0 0 4 4 4 0 DREPP plasma membrane polypeptide DUF3368 PF11848.3 ETS83518.1 - 0.58 9.7 21.9 27 4.4 0.0 11.4 15 0 0 15 15 15 0 Domain of unknown function (DUF3368) Antimicrobial_7 PF08102.6 ETS83518.1 - 2 8.4 7.0 82 3.3 0.0 5.3 7 0 0 7 7 7 0 Scorpion antimicrobial peptide DHC_N1 PF08385.7 ETS83518.1 - 2.5 6.3 16.0 2.7 6.2 0.1 6.3 7 1 1 8 8 8 0 Dynein heavy chain, N-terminal region 1 FlgN PF05130.7 ETS83518.1 - 4.5 7.5 28.5 0.5 10.6 0.5 7.6 4 1 5 9 9 9 0 FlgN protein Cytochrom_B_N PF00033.14 ETS83519.1 - 0.11 11.9 1.3 0.14 11.4 0.9 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB TraD_N PF12615.3 ETS83519.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 F sex factor protein N terminal FAD_binding_3 PF01494.14 ETS83520.1 - 7.6e-12 44.9 0.3 2.2e-10 40.1 0.2 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS83520.1 - 3.2e-06 27.0 0.0 9.6e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS83520.1 - 8.5e-05 21.6 0.8 0.015 14.2 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS83520.1 - 0.00054 18.9 0.0 0.00094 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS83520.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS83520.1 - 0.024 15.0 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS83520.1 - 0.1 11.4 0.1 0.94 8.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein SSF PF00474.12 ETS83521.1 - 2.9e-23 82.1 32.7 4.5e-23 81.5 22.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family NAD_binding_4 PF07993.7 ETS83522.1 - 1.1e-37 129.3 0.0 1.6e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS83522.1 - 2.3e-30 105.3 0.0 1.1e-29 103.1 0.0 2.0 3 0 0 3 3 3 1 AMP-binding enzyme Epimerase PF01370.16 ETS83522.1 - 2.9e-10 39.9 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS83522.1 - 2.1e-05 24.5 1.2 8.6e-05 22.5 0.5 2.4 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 ETS83522.1 - 0.00019 21.6 0.0 0.00046 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 ETS83522.1 - 0.0013 18.4 0.6 0.01 15.4 0.4 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS83522.1 - 0.071 13.1 0.2 6.4 6.7 0.1 3.1 1 1 0 2 2 2 0 NADH(P)-binding Dynamin_N PF00350.18 ETS83523.1 - 1.2e-35 122.7 0.0 2.6e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS83523.1 - 6.2e-20 71.1 0.0 5.8e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 ETS83523.1 - 0.00018 21.4 0.0 0.0015 18.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS83523.1 - 0.002 18.6 0.0 0.0074 16.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 ETS83523.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 ETS83523.1 - 0.06 13.6 0.0 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 ETS83523.1 - 0.1 12.8 0.1 1 9.6 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 ETS83523.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GED PF02212.13 ETS83523.1 - 0.76 9.7 4.0 1.5 8.7 0.1 3.2 3 0 0 3 3 3 0 Dynamin GTPase effector domain 2OG-FeII_Oxy PF03171.15 ETS83524.1 - 1.1e-18 67.2 0.0 1.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS83524.1 - 2.5e-15 57.0 0.1 6.6e-15 55.6 0.1 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DLH PF01738.13 ETS83525.1 - 9.3e-27 93.7 0.0 1.1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 ETS83525.1 - 1.7e-07 31.1 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS83525.1 - 0.00019 21.4 0.1 0.0014 18.5 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83525.1 - 0.027 14.0 0.0 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold ADH_N PF08240.7 ETS83527.1 - 2.2e-24 85.2 3.9 3.9e-24 84.4 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83527.1 - 3e-17 62.3 0.1 4.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS83527.1 - 6.8e-05 22.0 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 ETS83527.1 - 0.0011 19.8 0.0 0.0044 17.9 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 ETS83527.1 - 0.003 17.1 0.2 0.0048 16.5 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 ETS83527.1 - 0.055 13.2 0.1 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 ThiF family Sugar_tr PF00083.19 ETS83528.1 - 6.1e-128 427.2 23.5 7e-128 427.0 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83528.1 - 7.7e-29 100.5 38.2 4.4e-22 78.2 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VWA_3 PF13768.1 ETS83529.1 - 1.1e-21 77.1 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 ETS83529.1 - 1.1e-17 64.6 0.0 3.2e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 ETS83529.1 - 1.9e-14 53.3 0.0 7.9e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 ETS83529.1 - 4.9e-12 45.9 0.0 9.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 ETS83529.1 - 4.7e-07 29.1 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 ETS83529.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus VWA_CoxE PF05762.9 ETS83529.1 - 0.081 12.0 0.5 0.61 9.1 0.3 2.4 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein GrpE PF01025.14 ETS83531.1 - 0.15 11.6 0.5 0.33 10.4 0.3 1.6 1 1 0 1 1 1 0 GrpE DUF2296 PF10058.4 ETS83531.1 - 0.17 11.6 0.8 1 9.1 0.5 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Peptidase_S8 PF00082.17 ETS83532.1 - 2.7e-17 62.8 0.0 4.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family PYC_OADA PF02436.13 ETS83532.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain adh_short PF00106.20 ETS83534.1 - 3.7e-31 108.2 2.7 4.8e-31 107.9 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83534.1 - 5.4e-21 75.4 0.1 6.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83534.1 - 4.9e-12 45.8 2.0 1e-11 44.8 1.4 1.5 1 1 0 1 1 1 1 KR domain DFP PF04127.10 ETS83534.1 - 0.026 14.1 0.5 0.06 12.9 0.4 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 ETS83534.1 - 0.026 13.9 0.4 0.044 13.2 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 ETS83534.1 - 0.031 13.3 0.1 0.17 10.9 0.0 1.9 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AIRC PF00731.15 ETS83534.1 - 0.035 13.3 0.6 0.57 9.4 0.2 2.5 3 0 0 3 3 3 0 AIR carboxylase NAD_binding_2 PF03446.10 ETS83534.1 - 0.059 13.2 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 ETS83534.1 - 0.07 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 ETS83534.1 - 0.13 12.1 0.8 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.7 ETS83535.1 - 1.6e-32 111.5 0.9 1.6e-32 111.5 0.6 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83535.1 - 1.9e-23 82.4 0.4 3.2e-23 81.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS83535.1 - 0.00025 21.9 0.0 0.00062 20.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.15 ETS83535.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 ETS83535.1 - 0.015 15.8 0.1 0.055 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 ETS83535.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 ETS83535.1 - 0.032 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS83535.1 - 0.04 13.0 0.2 0.068 12.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_17 PF13207.1 ETS83536.1 - 9.1e-06 26.4 0.0 1.7e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 ETS83536.1 - 3.3e-05 23.5 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 ETS83536.1 - 0.00018 20.4 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 ETS83536.1 - 0.00018 21.4 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS83536.1 - 0.00056 19.6 2.1 0.0038 16.9 0.4 2.7 2 1 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 ETS83536.1 - 0.00062 20.0 0.0 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS83536.1 - 0.00086 19.5 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 ETS83536.1 - 0.001 18.1 0.1 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 ETS83536.1 - 0.0075 16.2 0.0 0.014 15.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETS83536.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 ETS83536.1 - 0.018 14.4 0.2 0.075 12.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 ETS83536.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 ETS83536.1 - 0.023 14.9 0.0 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.5 ETS83536.1 - 0.033 13.4 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 ETS83536.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 ETS83536.1 - 0.042 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETS83536.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 ETS83536.1 - 0.056 13.5 0.0 0.086 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 ETS83536.1 - 0.057 12.9 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 ETS83536.1 - 0.069 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 ETS83536.1 - 0.079 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 ETS83536.1 - 0.091 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_10 PF12846.2 ETS83536.1 - 0.095 12.1 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 ETS83536.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 ETS83536.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 ETS83536.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 ETS83536.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 ETS83536.1 - 0.16 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain adh_short PF00106.20 ETS83537.1 - 7.3e-29 100.8 6.5 8.9e-29 100.5 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83537.1 - 3.9e-21 75.9 0.1 6.2e-21 75.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83537.1 - 2.8e-14 53.2 4.7 4.7e-14 52.4 3.2 1.4 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 ETS83537.1 - 0.00031 19.8 0.3 0.00052 19.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETS83537.1 - 0.00068 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 ETS83537.1 - 0.0023 17.1 0.2 0.0046 16.1 0.1 1.5 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS83537.1 - 0.011 15.3 0.8 0.019 14.6 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 ETS83537.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS83537.1 - 0.034 14.1 1.6 0.098 12.6 1.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 ETS83537.1 - 0.042 12.5 0.1 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 ETS83537.1 - 0.044 14.0 0.2 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 ETS83537.1 - 0.07 13.2 0.2 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS83537.1 - 0.095 13.1 0.5 0.26 11.7 0.3 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ub-RnfH PF03658.9 ETS83537.1 - 0.13 12.1 0.1 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RnfH family Ubiquitin Sugar_tr PF00083.19 ETS83538.1 - 1.1e-86 291.1 24.1 1.3e-86 290.9 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83538.1 - 1.2e-28 99.8 29.2 4.4e-26 91.4 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS83538.1 - 5.8e-05 21.6 25.6 6.6e-05 21.4 0.6 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein Fungal_trans PF04082.13 ETS83539.1 - 5.4e-24 84.4 0.2 9e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83539.1 - 4.9e-07 29.5 11.0 7.9e-07 28.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 ETS83539.1 - 0.0049 16.7 3.4 0.0091 15.9 2.4 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain HsbA PF12296.3 ETS83541.1 - 8.3e-15 54.7 6.4 8.3e-15 54.7 4.5 1.3 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.7 ETS83541.1 - 1.1 9.5 3.8 16 5.8 0.4 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Transposase_22 PF02994.9 ETS83542.1 - 0.00032 19.3 5.0 0.00045 18.8 3.5 1.2 1 0 0 1 1 1 1 L1 transposable element Fez1 PF06818.10 ETS83542.1 - 0.039 13.9 8.2 0.061 13.3 5.7 1.3 1 0 0 1 1 1 0 Fez1 UPF0231 PF06062.6 ETS83542.1 - 0.076 12.8 0.9 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Mnd1 PF03962.10 ETS83542.1 - 0.23 11.0 6.4 0.48 10.0 4.4 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 ETS83542.1 - 0.4 9.6 7.3 0.59 9.1 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1409 PF07197.7 ETS83542.1 - 1.1 9.4 5.8 2.4 8.2 1.6 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1409) Thioredoxin PF00085.15 ETS83543.1 - 3.6e-23 81.2 0.0 5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 ETS83543.1 - 4e-07 29.9 0.1 6.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 ETS83543.1 - 3e-06 27.2 0.0 3.2e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS83543.1 - 5.5e-06 26.5 0.1 3.6e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 ETS83543.1 - 1.5e-05 24.6 0.0 9.4e-05 22.0 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 ETS83543.1 - 8.9e-05 22.0 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 ETS83543.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 ETS83543.1 - 0.031 14.1 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 ETS83543.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain HET PF06985.6 ETS83544.1 - 3.8e-21 75.7 7.7 3.8e-21 75.7 5.3 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS83545.1 - 9e-31 106.8 23.8 1e-30 106.6 15.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily FerA PF08165.6 ETS83546.1 - 0.046 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 FerA (NUC095) domain RskA PF10099.4 ETS83547.1 - 0.028 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA adh_short PF00106.20 ETS83549.1 - 3.2e-23 82.4 0.7 7e-23 81.3 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83549.1 - 5e-08 32.8 0.2 8e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS83549.1 - 0.0025 17.5 0.2 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 ETS83549.1 - 0.077 13.5 0.2 0.25 11.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 ETS83549.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Podoplanin PF05808.6 ETS83550.1 - 7.6e-06 25.5 6.0 1.3e-05 24.8 4.0 1.5 1 1 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 ETS83550.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 ETS83550.1 - 0.02 14.6 0.3 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.2 ETS83550.1 - 0.033 13.3 0.2 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CD99L2 PF12301.3 ETS83550.1 - 0.1 12.2 0.3 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 adh_short PF00106.20 ETS83551.1 - 8.2e-16 58.3 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83551.1 - 2e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS83551.1 - 9.4e-06 25.5 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS83551.1 - 0.0043 16.5 0.1 0.0099 15.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS83551.1 - 0.0052 16.8 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 ETS83552.1 - 5.4e-06 26.1 0.0 3.8e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83552.1 - 4.6e-05 22.9 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 ETS83553.1 - 6.7e-12 44.8 0.0 2.5e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain RRM_6 PF14259.1 ETS83554.1 - 5.9e-10 38.9 0.2 2.2e-09 37.1 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS83554.1 - 9.7e-09 34.7 1.4 7.2e-08 31.9 0.1 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 ETS83554.1 - 1.3e-05 25.1 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 ETS83554.1 - 1.8e-05 24.5 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS83554.1 - 0.00084 19.0 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 ETS83554.1 - 0.0066 16.1 5.2 0.011 15.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) OmpH PF03938.9 ETS83554.1 - 0.072 13.0 8.7 0.17 11.8 6.0 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mt_ATP-synt_B PF05405.9 ETS83554.1 - 0.32 10.4 5.1 0.65 9.4 3.5 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AAA_23 PF13476.1 ETS83554.1 - 0.75 10.0 8.9 1.7 8.9 6.2 1.6 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 ETS83554.1 - 1.1 7.4 9.7 1.8 6.7 6.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TMCO5 PF14992.1 ETS83554.1 - 6.2 5.8 11.9 10 5.1 8.2 1.2 1 0 0 1 1 1 0 TMCO5 family PHP PF02811.14 ETS83555.1 - 4.5e-09 36.3 0.0 7.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain MTHFR PF02219.12 ETS83556.1 - 1e-113 379.2 0.0 1.6e-113 378.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_31 PF13847.1 ETS83556.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain bZIP_2 PF07716.10 ETS83557.1 - 0.12 12.2 4.6 0.19 11.5 3.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper PSD5 PF07637.6 ETS83557.1 - 0.13 12.3 0.2 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) bZIP_1 PF00170.16 ETS83557.1 - 0.41 10.6 6.8 0.69 9.9 4.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor DEAD PF00270.24 ETS83558.1 - 7.7e-24 84.0 0.0 1.3e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 ETS83558.1 - 1.4e-13 51.1 0.3 4.3e-13 49.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 ETS83558.1 - 2e-10 40.3 0.2 1.4e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 ETS83558.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 DNA replication factor CDT1 like Kinesin PF00225.18 ETS83559.1 - 5.4e-45 153.5 0.0 1.6e-44 151.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Spc7 PF08317.6 ETS83559.1 - 0.0083 14.8 10.9 0.015 13.9 7.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_16 PF13191.1 ETS83559.1 - 0.02 14.8 3.5 0.06 13.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Bac_DnaA PF00308.13 ETS83559.1 - 0.06 12.9 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein ADIP PF11559.3 ETS83559.1 - 0.25 11.2 11.8 0.59 10.0 8.2 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 ETS83559.1 - 0.33 10.9 20.2 0.89 9.4 14.0 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ABC_tran PF00005.22 ETS83559.1 - 0.7 10.1 5.3 1.1 9.5 0.0 2.8 2 1 1 3 3 3 0 ABC transporter TMCO5 PF14992.1 ETS83559.1 - 1.2 8.2 11.1 1.9 7.5 7.7 1.3 1 0 0 1 1 1 0 TMCO5 family Phage_GP20 PF06810.6 ETS83559.1 - 1.3 8.4 11.2 0.21 10.9 3.9 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 SPX PF03105.14 ETS83559.1 - 1.7 8.3 10.6 3.2 7.4 7.3 1.5 1 0 0 1 1 1 0 SPX domain Atg14 PF10186.4 ETS83559.1 - 2.2 7.1 16.5 5.5 5.8 11.5 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 ETS83559.1 - 2.3 7.3 15.3 1.3 8.2 8.7 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 ETS83559.1 - 3.3 6.0 17.7 0.13 10.7 7.9 1.7 2 0 0 2 2 2 0 AAA domain ERM PF00769.14 ETS83559.1 - 4.3 6.8 26.7 16 4.9 12.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4446 PF14584.1 ETS83559.1 - 5.3 6.8 10.4 7.9 6.3 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) FMN_bind_2 PF04299.7 ETS83560.1 - 2.1e-50 170.5 0.1 2.8e-50 170.1 0.1 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain GFA PF04828.9 ETS83561.1 - 1.3e-10 41.0 1.4 2.1e-10 40.4 0.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme adh_short_C2 PF13561.1 ETS83562.1 - 1.5e-34 119.8 0.1 1.7e-34 119.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS83562.1 - 4e-22 78.8 1.5 6.1e-22 78.3 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS83562.1 - 3.7e-07 29.8 1.1 5.3e-06 26.0 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS83562.1 - 3.8e-06 26.6 0.1 6.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 ETS83562.1 - 0.17 11.5 1.6 0.41 10.2 1.1 1.7 1 1 0 1 1 1 0 YjeF-related protein N-terminus Metallophos PF00149.23 ETS83564.1 - 3e-42 144.3 0.6 3.6e-42 144.0 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 ETS83565.1 - 3.3e-57 193.1 1.0 3.6e-57 193.0 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 ETS83566.1 - 0.0033 17.0 0.0 0.024 14.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain AA_permease_2 PF13520.1 ETS83567.1 - 3.3e-45 154.3 47.6 4.2e-45 154.0 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS83567.1 - 4.3e-26 91.2 39.0 6.1e-26 90.8 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_Pyocin PF01320.13 ETS83569.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein TRI12 PF06609.8 ETS83571.1 - 1.4e-24 86.2 25.6 1.8e-24 85.8 17.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS83571.1 - 2.4e-20 72.5 53.8 2.4e-20 72.5 37.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily GFA PF04828.9 ETS83572.1 - 1.5e-15 56.9 0.2 1.5e-15 56.9 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Baculo_p47 PF05112.7 ETS83572.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein NAD_binding_2 PF03446.10 ETS83574.1 - 1.7e-40 138.5 0.1 2.6e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS83574.1 - 7.8e-31 106.6 0.1 1.8e-30 105.4 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 ETS83574.1 - 4.3e-08 33.4 0.0 1.4e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 ETS83574.1 - 8e-06 24.8 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 ETS83574.1 - 0.00038 20.9 0.1 0.0022 18.4 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 ETS83574.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 ETS83574.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Arena_glycoprot PF00798.13 ETS83574.1 - 0.15 10.4 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein RTA1 PF04479.8 ETS83575.1 - 1.4e-34 119.5 0.9 5e-34 117.7 0.2 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF4233 PF14017.1 ETS83575.1 - 0.22 11.4 4.8 1.3 8.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DUF4131 PF13567.1 ETS83575.1 - 1.6 8.0 9.6 0.37 10.1 0.2 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) Adaptin_N PF01602.15 ETS83576.1 - 4.2e-103 345.4 0.2 5.1e-103 345.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 ETS83576.1 - 3.4e-11 43.2 4.3 6.4e-05 23.1 0.0 4.6 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 ETS83576.1 - 5.6e-11 41.5 0.1 0.05 13.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.2 ETS83576.1 - 0.0035 17.2 5.3 0.66 10.0 0.0 4.4 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 ETS83576.1 - 0.0044 16.8 0.0 1.5 8.6 0.0 3.1 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 ETS83576.1 - 0.0087 16.5 8.9 0.22 12.0 0.0 5.3 5 2 2 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 ETS83576.1 - 0.029 13.7 0.2 19 4.4 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal VHS PF00790.14 ETS83576.1 - 0.11 12.1 1.8 25 4.4 0.0 3.7 4 0 0 4 4 4 0 VHS domain Nop14 PF04147.7 ETS83576.1 - 0.94 7.3 32.0 1.8 6.4 22.2 1.4 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 ETS83576.1 - 2.3 7.4 30.0 4.6 6.4 20.8 1.5 1 0 0 1 1 1 0 SDA1 Nuf2 PF03800.9 ETS83577.1 - 5.1e-45 153.0 0.1 5.1e-45 153.0 0.1 2.3 3 0 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 ETS83577.1 - 3.1 6.8 8.6 2.8 7.0 3.5 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Thioredoxin PF00085.15 ETS83579.1 - 7.4e-28 96.2 0.1 8.2e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS83579.1 - 1.2e-06 28.6 0.3 1.7e-05 24.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 ETS83579.1 - 5e-06 26.5 0.1 0.00028 20.9 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 ETS83579.1 - 2.2e-05 24.3 0.1 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 ETS83579.1 - 0.00099 18.7 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 ETS83579.1 - 0.0013 18.3 0.1 0.0031 17.0 0.1 1.6 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 ETS83579.1 - 0.0013 18.6 0.1 0.0033 17.3 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 ETS83579.1 - 0.0044 16.5 0.0 0.0049 16.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OPT PF03169.10 ETS83580.1 - 3.5e-166 554.2 55.2 4e-166 554.1 38.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLAC1 PF03595.12 ETS83581.1 - 1.8e-64 217.5 48.6 2e-64 217.3 33.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MMR_HSR1 PF01926.18 ETS83582.1 - 1.7e-09 37.6 0.0 3.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 ETS83582.1 - 4e-05 22.7 0.0 9.5e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 ETS83582.1 - 0.0003 19.9 0.7 0.0086 15.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 ETS83582.1 - 0.00033 19.8 0.0 0.001 18.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETS83582.1 - 0.0025 18.1 0.6 0.028 14.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 ETS83582.1 - 0.0031 17.3 5.2 0.45 10.3 0.0 3.3 2 1 0 3 3 3 1 Dynamin family DUF812 PF05667.6 ETS83582.1 - 0.0032 16.0 7.0 0.0043 15.6 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Miro PF08477.8 ETS83582.1 - 0.0039 17.6 0.2 0.02 15.3 0.0 2.2 2 1 1 3 3 3 1 Miro-like protein Not3 PF04065.10 ETS83582.1 - 0.023 13.9 6.4 0.046 12.9 4.4 1.5 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AAA_22 PF13401.1 ETS83582.1 - 0.036 14.2 0.4 0.16 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS83582.1 - 0.037 14.8 0.6 0.62 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 ETS83582.1 - 0.057 12.8 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Ras family MobB PF03205.9 ETS83582.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Tmemb_cc2 PF10267.4 ETS83582.1 - 0.07 11.7 11.4 0.12 10.9 7.7 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GTP_EFTU PF00009.22 ETS83582.1 - 0.092 12.1 0.2 0.57 9.5 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 ETS83582.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 Herpes_UL6 PF01763.11 ETS83582.1 - 0.18 9.9 4.5 0.23 9.5 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc7 PF08317.6 ETS83582.1 - 0.28 9.7 9.9 0.45 9.1 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 ETS83582.1 - 0.45 9.4 8.9 0.72 8.8 6.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETS83582.1 - 1.2 8.7 10.9 1.9 8.0 7.6 1.3 1 0 0 1 1 1 0 IncA protein MMR_HSR1 PF01926.18 ETS83583.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 ETS83583.1 - 0.00029 20.0 0.0 0.00067 18.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 ETS83583.1 - 0.00041 19.8 0.4 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 ETS83583.1 - 0.00051 19.2 0.1 0.0018 17.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 ETS83583.1 - 0.0025 17.9 0.2 0.0089 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 ETS83583.1 - 0.0035 17.1 6.1 0.4 10.4 0.4 3.2 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 ETS83583.1 - 0.0036 17.7 0.1 0.011 16.2 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein Septin PF00735.13 ETS83583.1 - 0.0039 16.2 0.0 0.012 14.6 0.0 1.8 1 1 0 1 1 1 1 Septin AAA_33 PF13671.1 ETS83583.1 - 0.0058 16.5 3.0 0.0094 15.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain DUF463 PF04317.7 ETS83583.1 - 0.0094 14.5 0.1 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 YcjX-like family, DUF463 IIGP PF05049.8 ETS83583.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 ETS83583.1 - 0.028 13.6 0.3 0.082 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 ETS83583.1 - 0.032 15.0 0.1 0.12 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS83583.1 - 0.033 14.1 2.4 0.083 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS83583.1 - 0.038 13.4 0.3 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 ETS83583.1 - 0.051 13.1 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 ETS83583.1 - 0.098 12.3 0.2 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 ETS83583.1 - 0.3 10.6 1.9 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family adh_short PF00106.20 ETS83584.1 - 9.3e-30 103.7 0.6 1.2e-29 103.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83584.1 - 7.7e-25 88.0 0.0 1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83584.1 - 1.3e-15 57.5 0.3 1.9e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS83584.1 - 0.00011 22.3 0.7 0.00014 21.8 0.5 1.4 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 ETS83584.1 - 0.019 14.0 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 ETS83584.1 - 0.02 14.4 0.7 4.2 6.9 0.1 2.3 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF1372 PF07116.6 ETS83584.1 - 0.043 13.7 0.1 0.091 12.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Epimerase PF01370.16 ETS83584.1 - 0.058 12.8 0.3 0.085 12.2 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family BATS PF06968.8 ETS83585.1 - 3.8e-30 103.5 0.1 1.4e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 ETS83585.1 - 2.1e-12 47.5 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.16 ETS83586.1 - 8.1e-37 127.0 0.0 9.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 ETS83586.1 - 0.038 12.5 0.0 0.15 10.5 0.0 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 ETS83586.1 - 0.041 12.9 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 ETS83587.1 - 8.1e-37 126.8 0.0 3e-19 69.0 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 ETS83587.1 - 7.9e-32 110.4 0.0 2.6e-31 108.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain CbiA PF01656.18 ETS83587.1 - 0.11 11.9 0.1 0.4 10.0 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CRAL_TRIO PF00650.15 ETS83588.1 - 2.5e-23 82.3 0.0 3.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS83588.1 - 1.2e-09 38.1 0.0 3.6e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.2 ETS83589.1 - 3.7e-60 202.4 0.0 4.9e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase LRV PF01816.12 ETS83589.1 - 0.019 15.0 1.4 0.13 12.4 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat variant Abhydrolase_6 PF12697.2 ETS83590.1 - 2.8e-05 24.1 0.1 0.00012 22.0 0.0 2.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETS83590.1 - 5e-05 22.6 0.0 0.00052 19.3 0.0 2.6 2 1 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.7 ETS83590.1 - 7.6e-05 22.4 0.1 0.00025 20.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS83590.1 - 8e-05 22.7 0.0 0.00088 19.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS83590.1 - 0.0021 18.0 0.5 0.018 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS83590.1 - 0.0045 16.7 0.0 0.021 14.5 0.0 2.1 3 0 0 3 3 3 1 Archaeal ATPase PGAP1 PF07819.8 ETS83590.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS83590.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_17 PF13207.1 ETS83590.1 - 0.063 14.0 0.9 0.63 10.8 0.6 2.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS83590.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyoxalase PF00903.20 ETS83591.1 - 8.2e-11 41.9 4.9 1.7e-06 28.0 1.4 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS83591.1 - 5.7e-05 23.6 1.9 0.0011 19.5 0.1 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain DUF2960 PF11173.3 ETS83591.1 - 0.054 13.8 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) CBM_1 PF00734.13 ETS83592.1 - 8.9e-13 47.6 7.7 8.9e-13 47.6 5.3 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain CENP-T PF15511.1 ETS83592.1 - 0.05 12.8 13.5 0.073 12.3 9.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 ETS83592.1 - 0.077 11.4 11.7 0.1 11.0 8.1 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 ETS83592.1 - 0.3 11.3 13.0 0.74 10.0 9.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 ETS83592.1 - 0.31 8.9 13.0 0.4 8.5 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 ETS83592.1 - 0.4 9.6 11.8 0.6 9.0 8.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 ETS83592.1 - 0.77 7.7 7.4 1.1 7.2 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 ETS83592.1 - 1.1 8.4 11.2 1.5 8.0 7.7 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.6 ETS83592.1 - 2.7 7.4 11.1 4.2 6.8 7.7 1.2 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.8 ETS83592.1 - 4.8 6.7 9.4 8.6 5.9 6.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 ETS83592.1 - 5.8 6.5 13.9 8.5 6.0 9.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.20 ETS83593.1 - 7.5e-24 84.2 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 ETS83593.1 - 8.5e-15 53.9 5.6 2.6e-08 33.4 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 ETS83593.1 - 1e-07 31.4 10.4 0.026 14.5 0.1 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 ETS83593.1 - 2e-06 27.9 4.2 0.0069 16.6 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats Pkinase_Tyr PF07714.12 ETS83593.1 - 0.00054 19.1 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 ETS83593.1 - 0.0074 16.7 5.0 1.1 9.7 0.4 4.1 5 0 0 5 5 5 2 HEAT-like repeat RasGEF_N_2 PF14663.1 ETS83593.1 - 0.23 11.4 0.0 0.69 9.8 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PAN_1 PF00024.21 ETS83594.1 - 6.6e-08 32.2 3.0 0.0037 16.9 0.4 2.4 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 ETS83594.1 - 1.6e-05 24.4 5.7 0.00057 19.5 0.5 2.4 2 0 0 2 2 2 2 PAN domain Nitrate_red_gam PF02665.9 ETS83594.1 - 0.019 14.3 0.2 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAN_3 PF08277.7 ETS83594.1 - 0.17 11.5 3.1 9 6.0 0.2 2.4 2 0 0 2 2 2 0 PAN-like domain Fungal_trans_2 PF11951.3 ETS83595.1 - 1.3e-35 122.7 6.6 1.1e-34 119.7 4.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83595.1 - 2.1e-07 30.7 9.1 3.6e-07 29.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Terminase_3 PF04466.8 ETS83595.1 - 0.081 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit ApbA_C PF08546.6 ETS83596.1 - 1.7e-29 102.3 0.0 6.5e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS83596.1 - 7.2e-23 80.6 0.0 1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HCV_NS4a PF01006.15 ETS83596.1 - 0.019 14.5 0.1 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Aminotran_1_2 PF00155.16 ETS83597.1 - 2e-16 59.8 0.0 2.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS83597.1 - 1.6e-07 30.2 0.0 1.2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 ETS83597.1 - 0.045 12.8 0.0 0.13 11.4 0.0 1.7 1 1 1 2 2 2 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 ETS83597.1 - 0.071 12.1 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 ETS83598.1 - 1.1e-28 100.0 45.0 1.1e-28 100.0 31.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83598.1 - 0.00084 18.0 43.0 0.034 12.7 12.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 ETS83598.1 - 0.32 9.3 46.3 0.004 15.6 9.3 3.0 1 1 2 3 3 3 0 MFS/sugar transport protein R3H-assoc PF13902.1 ETS83599.1 - 6.2e-20 71.4 4.7 7.9e-20 71.1 2.5 1.8 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 ETS83599.1 - 0.0088 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain BACON PF13004.2 ETS83599.1 - 0.077 13.2 0.3 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Pyr_redox_3 PF13738.1 ETS83600.1 - 1.6e-21 77.3 0.0 9.5e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS83600.1 - 4.7e-09 34.9 0.2 2.2e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS83600.1 - 4.3e-08 32.4 0.0 1.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS83600.1 - 3.3e-06 27.1 0.0 0.001 19.0 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83600.1 - 0.054 13.5 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 ETS83600.1 - 0.068 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 ETS83600.1 - 0.087 11.9 0.1 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2611 PF11022.3 ETS83604.1 - 5.9e-29 99.9 0.2 6.4e-29 99.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 ETS83605.1 - 7.6e-69 230.3 0.0 9.5e-69 230.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 ETS83606.1 - 2.2e-24 85.0 19.4 2.3e-12 46.5 4.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 ETS83606.1 - 0.0045 16.8 13.9 0.043 13.6 1.6 2.5 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 ETS83606.1 - 0.01 16.0 14.4 0.36 11.0 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.10 ETS83607.1 - 2.9e-29 101.3 0.2 2.9e-29 101.3 0.1 2.6 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 ETS83607.1 - 2.3e-28 97.6 0.1 4.3e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 ETS83607.1 - 1.8e-19 68.9 0.7 4.8e-19 67.6 0.5 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 ETS83607.1 - 1.8e-15 57.0 0.5 1.8e-15 57.0 0.3 3.8 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 ETS83607.1 - 0.0013 18.9 0.0 0.0073 16.5 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily p450 PF00067.17 ETS83608.1 - 8.1e-18 64.1 0.0 1.3e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PhzC-PhzF PF02567.11 ETS83609.1 - 5.7e-35 120.8 0.7 2.5e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Ion_trans PF00520.26 ETS83610.1 - 1.2e-06 27.9 14.2 1.2e-06 27.9 9.8 2.2 2 1 0 2 2 2 1 Ion transport protein DUF3814 PF12769.2 ETS83610.1 - 0.013 15.5 0.4 0.038 14.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) Ank_2 PF12796.2 ETS83611.1 - 7.4e-79 260.1 1.5 1.8e-14 53.8 0.0 7.1 5 1 0 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83611.1 - 5.6e-54 177.3 18.3 0.00018 21.1 0.0 16.0 15 1 1 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 ETS83611.1 - 1.1e-42 143.6 6.1 3e-07 30.7 0.0 12.4 6 5 8 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83611.1 - 9.2e-40 130.6 4.8 0.0081 16.3 0.0 14.7 15 0 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.1 ETS83611.1 - 1e-36 124.1 10.0 7e-07 29.2 0.1 11.4 5 4 8 13 13 13 10 Ankyrin repeats (many copies) FCD PF07729.7 ETS83611.1 - 0.0094 16.2 0.0 1.6 9.0 0.0 3.9 3 1 1 4 4 4 1 FCD domain DUF3447 PF11929.3 ETS83611.1 - 0.011 15.5 0.0 4.2 7.2 0.0 4.6 6 1 0 6 6 6 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 ETS83611.1 - 0.12 11.8 0.1 8.8 5.7 0.0 3.6 3 1 0 3 3 3 0 Shigella flexneri OspC protein EutQ PF06249.7 ETS83612.1 - 7.8e-10 38.4 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 ETS83612.1 - 8.3e-10 37.9 0.0 1.7e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 ETS83612.1 - 0.00011 21.5 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS83612.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Pirin PF02678.11 ETS83612.1 - 0.021 14.6 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Pirin DUF1859 PF08948.5 ETS83612.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) KduI PF04962.7 ETS83612.1 - 0.081 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family DUF3445 PF11927.3 ETS83613.1 - 7.6e-77 258.0 0.0 9.4e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 ETS83614.1 - 2.4e-26 92.2 1.0 5.4e-26 91.0 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83614.1 - 2.2e-07 30.6 9.2 3.9e-07 29.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.15 ETS83614.1 - 0.013 15.4 0.8 0.068 13.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S18 AD PF09793.4 ETS83614.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain Abhydrolase_6 PF12697.2 ETS83615.1 - 1.2e-19 71.1 0.1 1.5e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83615.1 - 3.2e-16 59.3 0.0 4.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS83615.1 - 8.2e-10 38.2 0.0 0.00036 19.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 ETS83615.1 - 1.1e-07 30.6 0.0 0.0042 15.6 0.0 2.4 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 ETS83615.1 - 3.2e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 ETS83615.1 - 0.00013 20.6 0.0 0.00021 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 ETS83615.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 ETS83615.1 - 0.0047 16.2 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family PhoPQ_related PF10142.4 ETS83615.1 - 0.15 10.5 0.0 0.34 9.3 0.0 1.6 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein ADH_N PF08240.7 ETS83616.1 - 1.5e-10 40.7 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83616.1 - 3e-09 36.5 0.0 4.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS83616.1 - 3.2e-06 28.0 0.0 5.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 ETS83616.1 - 0.0074 16.3 1.4 0.013 15.4 1.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding YhfZ_C PF14503.1 ETS83616.1 - 0.12 11.7 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 YhfZ C-terminal domain p450 PF00067.17 ETS83618.1 - 6.7e-40 136.9 0.0 8e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CinA PF02464.12 ETS83619.1 - 3.6e-33 114.1 0.2 4.1e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein DUF1929 PF09118.6 ETS83620.1 - 3.2e-24 84.8 0.2 7.3e-24 83.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.21 ETS83620.1 - 5e-16 58.2 11.8 5.2e-08 32.5 0.4 2.4 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.1 ETS83620.1 - 8.1e-15 54.3 7.0 0.00045 19.9 0.0 5.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 ETS83620.1 - 2.6e-14 52.4 2.0 0.00018 20.9 0.3 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 ETS83620.1 - 6.7e-12 45.0 7.7 0.0066 16.5 0.0 5.4 3 2 2 5 5 5 3 Kelch motif Kelch_2 PF07646.10 ETS83620.1 - 2.4e-08 33.4 1.1 0.0026 17.4 0.1 4.7 4 0 0 4 4 4 2 Kelch motif PAN_4 PF14295.1 ETS83620.1 - 1e-06 28.3 15.3 0.00026 20.6 1.3 3.1 3 0 0 3 3 3 2 PAN domain Glyoxal_oxid_N PF07250.6 ETS83620.1 - 2.3e-06 26.8 0.9 0.0061 15.6 0.0 3.2 2 2 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 ETS83620.1 - 0.00033 20.7 6.8 1.9 8.7 0.3 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain PAN_2 PF08276.6 ETS83620.1 - 0.051 13.4 13.2 0.38 10.6 2.5 2.5 2 0 0 2 2 2 0 PAN-like domain MANEC PF07502.9 ETS83620.1 - 0.24 11.4 7.9 3.8 7.5 1.5 2.5 2 0 0 2 2 2 0 MANEC domain PAN_3 PF08277.7 ETS83620.1 - 1.2 8.8 11.2 0.67 9.6 2.7 2.6 2 0 0 2 2 2 0 PAN-like domain Hydrolase PF00702.21 ETS83621.1 - 8.9e-22 78.5 0.0 1.4e-20 74.6 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 ETS83621.1 - 3.2e-21 75.4 0.0 7.2e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETS83621.1 - 1.6e-19 70.8 0.1 3.9e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS83621.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS83621.1 - 0.013 15.1 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS83621.1 - 0.068 12.6 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus UPF0052 PF01933.13 ETS83622.1 - 1.4e-54 185.5 0.0 1.7e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Sugar_tr PF00083.19 ETS83623.1 - 2e-79 267.2 21.0 2.4e-79 267.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83623.1 - 3.2e-18 65.5 29.7 7.2e-17 61.1 18.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 ETS83624.1 - 8.6e-58 195.0 2.3 2.3e-57 193.6 1.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS83624.1 - 3e-47 160.5 11.4 3e-47 160.5 7.9 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS83624.1 - 3.8e-32 112.4 0.2 1.6e-31 110.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS83624.1 - 6.2e-18 64.5 0.0 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS83624.1 - 3.4e-16 59.9 0.0 6.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS83624.1 - 2.3e-11 43.0 1.6 1.1e-10 40.8 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS83624.1 - 4.9e-06 26.3 0.4 0.00049 19.7 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3278 PF11683.3 ETS83624.1 - 0.21 11.5 5.1 0.047 13.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) FSH1 PF03959.8 ETS83625.1 - 1.5e-30 106.2 0.0 3.8e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 ETS83625.1 - 0.00057 19.8 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sulfate_transp PF00916.15 ETS83626.1 - 2.7e-56 190.6 4.7 2.7e-56 190.6 3.2 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETS83626.1 - 3.5e-29 100.3 5.5 3.8e-29 100.1 2.1 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 ETS83626.1 - 2.6e-19 68.7 0.0 4.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 ETS83626.1 - 9.2e-06 25.6 0.1 0.00029 20.8 0.0 2.7 2 1 0 2 2 2 1 STAS domain p450 PF00067.17 ETS83627.1 - 3e-74 250.2 0.0 3.8e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 ETS83628.1 - 7.3e-05 22.5 8.5 0.00038 20.2 5.9 2.1 1 1 0 1 1 1 1 CFEM domain FAD_binding_3 PF01494.14 ETS83629.1 - 6.2e-33 114.3 0.1 2.1e-32 112.5 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS83629.1 - 4.1e-09 35.8 0.1 0.00064 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS83629.1 - 6.5e-06 25.4 1.0 0.027 13.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 ETS83629.1 - 1.5e-05 24.1 0.4 0.00013 21.0 0.3 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS83629.1 - 6.6e-05 23.0 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83629.1 - 6.8e-05 22.8 0.4 0.0004 20.3 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS83629.1 - 0.0013 19.0 2.1 0.01 16.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS83629.1 - 0.0038 16.3 0.0 0.0087 15.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 ETS83629.1 - 0.0056 16.9 0.0 0.013 15.7 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 ETS83629.1 - 0.0093 15.8 0.3 0.023 14.5 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS83629.1 - 0.015 14.1 0.7 0.035 12.9 0.5 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 ETS83629.1 - 0.024 14.4 1.0 9.1 6.0 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 ETS83629.1 - 0.027 12.9 0.3 0.14 10.5 0.2 1.9 1 1 0 1 1 1 0 HI0933-like protein SE PF08491.5 ETS83629.1 - 0.033 13.0 0.0 0.69 8.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase SCPU PF05229.10 ETS83629.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain GFA PF04828.9 ETS83630.1 - 1.4e-19 69.7 2.3 4e-10 39.4 1.6 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 ETS83630.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF1517 PF07466.6 ETS83631.1 - 0.052 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TMEM154 PF15102.1 ETS83631.1 - 0.1 12.3 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Whi5 PF08528.6 ETS83632.1 - 5.9e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Rick_17kDa_Anti PF05433.10 ETS83633.1 - 5.8e-05 22.6 14.1 5.8e-05 22.6 9.8 3.0 2 2 1 3 3 3 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 ETS83633.1 - 0.002 17.5 9.9 0.002 17.5 6.8 2.8 3 0 0 3 3 3 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 ETS83633.1 - 0.0031 17.1 3.0 0.0031 17.1 2.1 2.6 2 1 1 3 3 3 1 Glycine-zipper containing OmpA-like membrane domain ATPase_gene1 PF09527.5 ETS83633.1 - 0.43 10.4 4.3 0.78 9.5 3.0 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) Alpha-amylase PF00128.19 ETS83634.1 - 4.9e-94 315.2 0.2 1.4e-93 313.7 0.0 1.8 1 1 1 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 ETS83634.1 - 1.6e-05 24.0 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Rifin_STEVOR PF02009.11 ETS83636.1 - 0.00037 20.2 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF1191 PF06697.7 ETS83636.1 - 0.0036 16.1 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) gpUL132 PF11359.3 ETS83636.1 - 0.011 15.0 2.5 0.011 15.0 1.7 2.3 1 1 1 2 2 2 0 Glycoprotein UL132 Syndecan PF01034.15 ETS83636.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.1 ETS83636.1 - 0.032 13.9 6.9 0.12 12.0 4.4 2.1 1 1 0 1 1 1 0 TMEM154 protein family Plasmodium_Vir PF05795.6 ETS83636.1 - 0.065 12.4 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EphA2_TM PF14575.1 ETS83636.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 ETS83637.1 - 1.7e-11 43.4 15.7 1.7e-11 43.4 10.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS83637.1 - 7.5e-05 22.2 1.3 0.00019 20.9 0.9 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 zf-C2H2_4 PF13894.1 ETS83638.1 - 8.8e-10 38.2 27.1 0.00048 20.2 1.3 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS83638.1 - 3.4e-08 33.3 0.7 3.4e-08 33.3 0.5 4.1 4 1 0 4 4 3 2 Zinc-finger double domain zf-met PF12874.2 ETS83638.1 - 4.9e-08 32.9 11.3 0.021 14.9 1.0 3.8 3 0 0 3 3 3 3 Zinc-finger of C2H2 type NACHT PF05729.7 ETS83638.1 - 1.8e-07 30.9 0.0 6.3e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.21 ETS83638.1 - 8.1e-05 22.7 1.8 8.1e-05 22.7 1.3 5.9 6 0 0 6 6 5 2 Zinc finger, C2H2 type AAA PF00004.24 ETS83638.1 - 0.0047 17.1 0.2 0.023 14.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.2 ETS83638.1 - 0.016 15.3 2.5 0.016 15.3 1.7 4.1 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) NB-ARC PF00931.17 ETS83638.1 - 0.016 14.0 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 ETS83638.1 - 0.019 14.9 0.0 0.07 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_jaz PF12171.3 ETS83638.1 - 0.021 14.9 13.8 0.14 12.3 0.7 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2075 PF09848.4 ETS83638.1 - 0.024 13.6 0.0 0.17 10.8 0.0 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 ETS83638.1 - 0.025 13.9 0.0 0.12 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS83638.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS83638.1 - 0.074 12.9 0.0 0.66 9.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS83638.1 - 0.086 13.6 0.3 2.5 8.9 0.1 3.5 2 1 0 2 2 2 0 AAA domain zf-C2H2_6 PF13912.1 ETS83638.1 - 3.1 7.8 8.2 4.8 7.2 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.18 ETS83639.1 - 5e-48 163.4 0.0 8.6e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83639.1 - 2.2e-05 24.2 0.1 9.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS83639.1 - 0.00017 21.1 0.0 0.0017 17.8 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 ETS83639.1 - 0.076 12.8 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rib_5-P_isom_A PF06026.9 ETS83640.1 - 8.9e-38 129.3 0.0 6.8e-37 126.4 0.0 1.9 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ras PF00071.17 ETS83641.1 - 1.7e-46 157.5 0.3 2.5e-46 157.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 ETS83641.1 - 2.1e-12 46.6 0.3 2.6e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 ETS83641.1 - 3e-11 43.8 0.2 5.3e-11 43.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 ETS83641.1 - 6e-07 29.0 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS83641.1 - 0.002 17.3 0.2 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_tran_WbsX PF14307.1 ETS83641.1 - 0.051 12.7 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Nop53 PF07767.6 ETS83642.1 - 7e-98 328.1 31.5 8.9e-98 327.7 21.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Pyr_redox_2 PF07992.9 ETS83643.1 - 3.3e-23 82.6 0.0 5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS83643.1 - 9.5e-15 54.7 0.0 2e-10 40.9 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 ETS83643.1 - 2e-05 23.5 0.2 4.6e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 ETS83643.1 - 0.00012 21.3 1.1 0.00026 20.1 0.7 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 ETS83643.1 - 0.00016 21.3 0.3 0.00016 21.3 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 ETS83643.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 ETS83643.1 - 0.012 15.6 0.0 1.9 8.5 0.0 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cyclase PF04199.8 ETS83644.1 - 3.7e-14 52.7 0.1 5.8e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase DUF77 PF01910.12 ETS83645.1 - 8.7e-33 111.8 0.2 1e-32 111.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 ETS83645.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family Polysacc_deac_1 PF01522.16 ETS83645.1 - 0.039 13.5 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Period_C PF12114.3 ETS83646.1 - 0.53 9.8 20.2 0.022 14.3 8.9 2.2 2 0 0 2 2 2 0 Period protein 2/3C-terminal region CDC37_N PF03234.9 ETS83647.1 - 7.6e-57 192.4 4.4 7.6e-57 192.4 3.1 2.9 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 ETS83647.1 - 1.1e-45 155.2 2.2 6.2e-45 152.7 0.8 2.4 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 ETS83647.1 - 3.7e-22 78.0 2.3 3.7e-22 78.0 1.6 2.7 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF2762 PF10960.3 ETS83647.1 - 0.00083 19.0 0.3 0.0039 16.8 0.2 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2762) XPG_I_2 PF12813.2 ETS83647.1 - 0.012 15.1 0.1 0.031 13.7 0.1 1.7 1 0 0 1 1 1 0 XPG domain containing TipAS PF07739.8 ETS83647.1 - 0.02 15.2 1.3 0.058 13.7 0.1 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF1268 PF06896.6 ETS83647.1 - 0.11 12.8 0.3 0.11 12.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1268) DUF1682 PF07946.9 ETS83648.1 - 1.3e-105 352.8 0.7 1.4e-105 352.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1803 PF08820.5 ETS83648.1 - 0.069 12.8 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) SAD_SRA PF02182.12 ETS83649.1 - 5e-06 25.9 0.0 8.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain NUT_N PF12881.2 ETS83649.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 NUT protein N terminus Rotamase PF00639.16 ETS83650.1 - 3.4e-10 40.5 2.1 3.8e-10 40.3 0.1 2.1 2 1 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 ETS83650.1 - 1.7e-09 37.9 1.6 2.3e-07 31.1 0.1 2.7 1 1 2 3 3 3 2 PPIC-type PPIASE domain Rotamase_2 PF13145.1 ETS83650.1 - 0.12 12.9 2.1 0.43 11.2 0.0 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain adh_short PF00106.20 ETS83651.1 - 1e-20 74.3 0.1 3.2e-20 72.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83651.1 - 1.1e-08 35.0 0.1 5.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS83651.1 - 2.1e-06 27.6 0.0 6.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS83651.1 - 0.0031 16.9 0.0 0.0074 15.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS83651.1 - 0.0068 16.1 0.1 0.021 14.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 ETS83651.1 - 0.0094 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 ETS83651.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 ETS83651.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 ETS83651.1 - 0.02 14.5 0.1 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2493 PF10686.4 ETS83651.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) NAD_binding_10 PF13460.1 ETS83651.1 - 0.095 12.7 0.2 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding AATase PF07247.7 ETS83652.1 - 3.3e-14 52.3 0.0 7.3e-14 51.1 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 ETS83652.1 - 0.095 11.5 0.2 0.42 9.4 0.0 1.8 2 0 0 2 2 2 0 Condensation domain Ribosomal_L7Ae PF01248.21 ETS83653.1 - 1.5e-28 98.1 0.7 1.9e-28 97.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 ETS83653.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ribosomal_S8 PF00410.14 ETS83654.1 - 2.1e-25 89.0 0.0 2.9e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.7 ETS83655.1 - 2.8e-16 59.2 6.7 7.6e-14 51.2 4.7 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 RNA_pol_Rpc82 PF05645.8 ETS83655.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Tox-URI2 PF15653.1 ETS83655.1 - 1.2 9.3 3.6 0.66 10.2 0.5 2.0 2 0 0 2 2 2 0 URI fold toxin 2 Catalase PF00199.14 ETS83656.1 - 9.5e-161 534.7 0.2 1.3e-160 534.2 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 ETS83656.1 - 5.8e-20 70.9 0.0 1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF3635 PF12330.3 ETS83657.1 - 3.1e-05 23.9 0.1 0.00035 20.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) MOSC PF03473.12 ETS83659.1 - 5.7e-22 77.6 0.0 1.2e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 ETS83659.1 - 8e-12 44.7 2.6 9.9e-12 44.4 1.1 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.9 ETS83659.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.7 ETS83659.1 - 0.011 15.6 0.2 0.87 9.4 0.0 2.5 2 1 1 3 3 3 0 Ferric reductase NAD binding domain SBP_bac_6 PF13343.1 ETS83659.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DSX_dimer PF08828.5 ETS83659.1 - 0.12 11.9 0.1 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Doublesex dimerisation domain TBCC PF07986.7 ETS83660.1 - 1.1e-33 115.1 0.1 1.7e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Med9 PF07544.8 ETS83661.1 - 1.6e-19 69.4 0.5 2.9e-19 68.5 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HemX PF04375.9 ETS83661.1 - 0.00096 17.8 6.5 0.0012 17.4 4.5 1.1 1 0 0 1 1 1 1 HemX Med21 PF11221.3 ETS83661.1 - 0.011 15.6 12.4 0.039 13.9 8.6 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex SlyX PF04102.7 ETS83661.1 - 0.012 15.9 1.3 0.012 15.9 0.9 2.5 3 0 0 3 3 1 0 SlyX Fib_alpha PF08702.5 ETS83661.1 - 0.022 14.8 0.1 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ASD2 PF08687.6 ETS83661.1 - 0.03 13.6 1.8 0.03 13.6 1.3 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Golgin_A5 PF09787.4 ETS83661.1 - 0.053 12.0 3.2 0.064 11.7 2.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CPSF100_C PF13299.1 ETS83661.1 - 0.076 13.1 0.6 0.12 12.5 0.2 1.5 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SPX PF03105.14 ETS83661.1 - 0.079 12.7 0.2 0.097 12.4 0.1 1.1 1 0 0 1 1 1 0 SPX domain zf-C4H2 PF10146.4 ETS83661.1 - 0.15 12.0 16.0 1.8 8.5 0.3 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4140 PF13600.1 ETS83661.1 - 0.35 11.3 7.0 0.18 12.2 2.2 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TFIIA PF03153.8 ETS83661.1 - 0.85 9.4 6.8 1 9.2 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.7 ETS83661.1 - 1.5 8.6 14.7 4 7.3 9.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Pex14_N PF04695.8 ETS83661.1 - 6.6 6.7 9.3 14 5.7 6.5 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region iPGM_N PF06415.8 ETS83662.1 - 3.8e-75 252.0 0.0 5e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 ETS83662.1 - 1e-69 234.7 0.1 1.3e-69 234.4 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 ETS83662.1 - 3.5e-06 26.5 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS83662.1 - 0.00012 21.3 0.0 0.00036 19.8 0.0 1.9 1 1 0 1 1 1 1 Sulfatase PCI_Csn8 PF10075.4 ETS83663.1 - 2.1e-40 137.8 0.0 2.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 ETS83663.1 - 3.7e-21 75.6 0.0 4.9e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FA_desaturase PF00487.19 ETS83664.1 - 5.3e-26 91.6 30.2 9e-26 90.8 20.9 1.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 ETS83664.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank_2 PF12796.2 ETS83665.1 - 9.6e-21 73.9 0.7 2.3e-09 37.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS83665.1 - 6.9e-17 61.0 1.5 4.7e-08 33.0 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 ETS83665.1 - 9.3e-16 56.7 3.0 0.0018 18.0 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 ETS83665.1 - 3.1e-15 56.1 0.5 2.5e-06 27.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83665.1 - 5.8e-10 38.4 0.5 0.026 14.7 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat CorA PF01544.13 ETS83665.1 - 0.0002 20.5 3.1 0.00074 18.6 2.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SICA_C PF12879.2 ETS83666.1 - 0.012 15.4 13.7 0.46 10.3 6.0 2.3 1 1 1 2 2 2 0 SICA C-terminal inner membrane domain Trypan_PARP PF05887.6 ETS83666.1 - 0.015 15.1 34.5 0.25 11.1 11.6 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) TEX19 PF15553.1 ETS83666.1 - 0.74 9.6 8.6 24 4.7 5.9 2.2 1 1 0 1 1 1 0 Testis-expressed protein 19 FAM74 PF15026.1 ETS83666.1 - 1.5 8.4 12.3 1.4e+03 -1.2 8.6 2.9 1 1 0 1 1 1 0 FAM74 protein Cyclase PF04199.8 ETS83667.1 - 4.9e-12 45.8 0.0 7.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Lactonase PF10282.4 ETS83668.1 - 9e-21 74.3 5.4 1.2e-19 70.6 2.6 2.2 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 ETS83668.1 - 0.00045 19.6 0.5 0.0021 17.5 0.2 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Pyr_redox_3 PF13738.1 ETS83670.1 - 1.9e-20 73.8 0.0 3.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS83670.1 - 5e-17 61.3 0.6 4.4e-13 48.2 0.1 3.1 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS83670.1 - 1.7e-09 37.5 0.8 4.7e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS83670.1 - 1.3e-07 30.8 0.0 0.00018 20.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS83670.1 - 3.6e-07 30.2 0.0 0.00012 21.9 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS83670.1 - 0.00027 20.7 3.6 0.029 14.1 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 ETS83670.1 - 0.004 16.1 0.0 0.88 8.4 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS83670.1 - 0.0047 16.0 0.3 0.083 11.9 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 ETS83670.1 - 0.03 14.7 0.9 3 8.3 0.0 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS83670.1 - 0.75 8.1 2.3 1.1 7.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 ETS83670.1 - 1.3 7.8 4.6 2.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Cyclin PF08613.6 ETS83671.1 - 1.1e-16 61.5 0.1 3.1e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS83671.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_3 PF07859.8 ETS83672.1 - 2.3e-57 193.9 0.0 3e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS83672.1 - 3.8e-07 29.1 0.0 1.8e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS83672.1 - 9.6e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS83672.1 - 0.00085 18.6 0.0 0.0031 16.7 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS83672.1 - 0.0041 17.0 0.4 0.0096 15.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 ETS83672.1 - 0.046 12.9 0.2 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase GTP_EFTU PF00009.22 ETS83673.1 - 3.3e-53 179.9 0.0 7.1e-53 178.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 ETS83673.1 - 1.1e-15 57.2 0.0 3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 ETS83673.1 - 3.2e-09 36.7 0.0 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 ETS83673.1 - 1.7e-07 30.9 0.0 5.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 ETS83673.1 - 0.00046 19.7 0.0 0.0031 17.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor G, domain IV SET PF00856.23 ETS83673.1 - 0.0044 17.3 0.3 0.93 9.7 0.0 3.1 3 0 0 3 3 3 1 SET domain MMR_HSR1 PF01926.18 ETS83673.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Herpes_DNAp_acc PF04929.7 ETS83673.1 - 0.13 11.1 0.0 0.66 8.8 0.0 1.9 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Paf67 PF10255.4 ETS83674.1 - 9.6e-155 515.4 0.6 1.1e-154 515.1 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 ETS83674.1 - 0.032 14.1 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 ETS83676.1 - 1.7e-14 54.1 2.7 6.4e-14 52.3 0.0 2.5 2 1 1 3 3 3 1 Universal stress protein family ThiS-like PF14453.1 ETS83676.1 - 0.024 14.4 0.1 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 ThiS-like ubiquitin Rep_fac-A_C PF08646.5 ETS83676.1 - 0.068 12.8 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Peptidase_C15 PF01470.12 ETS83677.1 - 0.0071 16.1 0.0 0.28 10.9 0.0 2.7 2 1 0 2 2 2 2 Pyroglutamyl peptidase GCV_T PF01571.16 ETS83678.1 - 1.1e-09 38.0 0.0 2.6e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS83678.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Cwf_Cwc_15 PF04889.7 ETS83679.1 - 8.4 6.0 22.2 0.88 9.2 3.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DEAD PF00270.24 ETS83680.1 - 5.4e-39 133.3 0.1 1.7e-38 131.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS83680.1 - 4.2e-27 93.8 0.1 1.4e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS83680.1 - 0.002 18.2 0.0 0.02 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.18 ETS83680.1 - 0.03 13.1 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 ETS83680.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 ETS83681.1 - 6.9e-60 202.3 0.0 8.3e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83681.1 - 4.7e-35 120.9 0.0 6.3e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS83681.1 - 6.8e-08 31.8 0.0 1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 ETS83681.1 - 0.27 10.0 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SET PF00856.23 ETS83682.1 - 3.5e-13 50.1 0.1 8.7e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 ETS83682.1 - 6.3e-06 26.0 2.3 0.0026 17.6 0.1 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS83682.1 - 0.016 15.0 0.3 0.059 13.3 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 ETS83683.1 - 1.4e-22 79.6 0.7 2.9e-22 78.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain KTI12 PF08433.5 ETS83684.1 - 3.4e-69 233.0 0.0 5.5e-69 232.3 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 ETS83684.1 - 0.00083 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS83684.1 - 0.0017 18.6 0.3 0.045 14.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETS83684.1 - 0.01 16.6 0.0 0.028 15.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 ETS83684.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 ETS83684.1 - 0.065 13.1 0.0 1.6 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1792 PF08759.6 ETS83684.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) DUF3397 PF11877.3 ETS83686.1 - 1.7 8.6 9.3 0.22 11.5 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3397) SUR7 PF06687.7 ETS83686.1 - 3.6 7.0 6.7 0.54 9.7 0.3 2.3 1 1 1 2 2 2 0 SUR7/PalI family Esterase_phd PF10503.4 ETS83687.1 - 1.8e-06 27.3 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 ETS83687.1 - 6.8e-06 25.8 0.0 9.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS83687.1 - 0.037 13.2 0.0 0.14 11.3 0.0 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family Pro_isomerase PF00160.16 ETS83688.1 - 2.4e-47 161.0 0.0 6.2e-47 159.6 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 ETS83688.1 - 0.0009 19.1 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 U-box domain Lung_7-TM_R PF06814.8 ETS83689.1 - 5.4e-68 229.0 17.2 6.5e-68 228.8 11.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 ETS83689.1 - 0.27 11.3 22.7 0.15 12.2 2.0 3.7 1 1 3 4 4 4 0 PrgI family protein DUF4131 PF13567.1 ETS83689.1 - 10 5.5 15.2 0.11 11.8 0.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Condensation PF00668.15 ETS83690.1 - 3.8e-29 101.4 0.0 5.7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.10 ETS83690.1 - 0.0078 14.7 0.3 0.02 13.3 0.0 1.6 1 1 1 2 2 2 1 Transferase family FAD_binding_3 PF01494.14 ETS83691.1 - 9.5e-19 67.6 0.2 1.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 ETS83691.1 - 0.00014 20.5 0.7 0.24 10.0 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 ETS83691.1 - 0.00022 20.4 0.2 0.00035 19.7 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS83691.1 - 0.0014 17.5 1.8 0.01 14.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS83691.1 - 0.0014 18.9 0.2 0.78 10.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS83691.1 - 0.0016 17.4 0.4 0.0041 16.0 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 ETS83691.1 - 0.003 16.7 0.0 0.003 16.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS83691.1 - 0.078 12.5 1.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 ETS83691.1 - 0.079 11.7 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 ETS83691.1 - 0.11 12.5 0.0 0.53 10.3 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E1-E2_ATPase PF00122.15 ETS83692.1 - 8.3e-21 74.0 0.1 1.4e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 ETS83692.1 - 1.5e-19 70.9 0.1 6e-19 68.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS83692.1 - 3.4e-14 53.7 0.1 1.9e-13 51.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS83692.1 - 1.3e-12 47.4 0.0 3.7e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS83692.1 - 0.00011 21.9 0.7 0.00029 20.4 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS83692.1 - 0.0096 16.1 0.1 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Gp_dh_N PF00044.19 ETS83692.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Acyl_transf_3 PF01757.17 ETS83692.1 - 4.8 5.9 25.2 0.022 13.5 10.8 1.9 3 0 0 3 3 3 0 Acyltransferase family Abhydrolase_6 PF12697.2 ETS83693.1 - 1.5e-29 103.4 0.0 2.3e-29 102.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83693.1 - 1.9e-16 60.3 0.0 1.2e-14 54.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS83693.1 - 4.6e-13 49.1 0.0 1.1e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS83693.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 ETS83693.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.11 ETS83693.1 - 0.13 11.6 0.0 1 8.7 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Methyltransf_23 PF13489.1 ETS83694.1 - 5.7e-19 68.4 0.0 9.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS83694.1 - 2.6e-07 30.3 0.0 2.5e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS83694.1 - 2.9e-07 31.0 0.0 4.9e-05 23.8 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS83694.1 - 7.4e-07 29.5 0.0 1.8e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS83694.1 - 1.1e-06 29.0 0.0 7.1e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS83694.1 - 0.019 14.0 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS83694.1 - 0.12 12.3 0.2 6.2 6.8 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Mso1_Sec1_bdg PF14475.1 ETS83696.1 - 5.5 6.4 7.1 2.1 7.7 1.5 2.2 2 0 0 2 2 2 0 Sec1-binding region of Mso1 MAP7 PF05672.6 ETS83697.1 - 0.005 16.2 19.7 0.005 16.2 13.7 1.9 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family Pex26 PF07163.7 ETS83697.1 - 0.0084 15.0 0.7 0.015 14.1 0.5 1.4 1 0 0 1 1 1 1 Pex26 protein Ribonuc_L-PSP PF01042.16 ETS83697.1 - 0.047 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP DUF1451 PF07295.6 ETS83697.1 - 2 8.1 7.5 3.7 7.3 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) PHF5 PF03660.9 ETS83698.1 - 7.5e-46 154.6 11.7 8.3e-46 154.4 8.1 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 ETS83698.1 - 0.28 11.0 14.1 4.8 7.0 9.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 ETS83698.1 - 0.83 9.4 14.6 2.6 7.8 0.5 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 ETS83698.1 - 2.7 7.7 14.0 0.17 11.5 4.5 2.3 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 ETS83699.1 - 3.3e-24 84.9 10.9 3.3e-24 84.9 7.5 1.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Ndc1_Nup PF09531.5 ETS83699.1 - 5.1 5.4 6.6 7 4.9 4.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 ETS83700.1 - 3e-16 59.1 28.2 3e-16 59.1 19.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS83700.1 - 9.3e-05 20.8 7.7 0.00017 19.9 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_2 PF07992.9 ETS83701.1 - 4.7e-27 95.1 0.1 6.2e-17 62.1 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS83701.1 - 4.3e-13 49.4 0.3 4.1e-11 43.1 0.1 3.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS83701.1 - 0.0028 17.7 0.4 1 9.4 0.0 3.7 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS83701.1 - 0.031 14.5 0.4 2.6 8.3 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding RPE65 PF03055.10 ETS83702.1 - 6.3e-86 288.8 0.0 7.8e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.13 ETS83703.1 - 9.7e-33 113.1 0.3 1.7e-32 112.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.14 ETS83704.1 - 4.9e-41 140.7 0.0 2.6e-40 138.4 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS83704.1 - 4.4e-25 88.6 0.0 7.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS83704.1 - 0.00018 20.5 0.3 0.0006 18.8 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 ETS83704.1 - 0.00035 19.6 0.3 0.0012 17.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS83704.1 - 0.00079 19.5 0.1 0.88 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83704.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS83704.1 - 0.0022 16.8 0.3 0.0054 15.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 ETS83704.1 - 0.0031 16.6 0.2 0.0064 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETS83704.1 - 0.04 12.3 0.2 0.06 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 ETS83704.1 - 0.045 12.6 0.2 0.43 9.4 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 ETS83704.1 - 0.045 12.8 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Use1 PF09753.4 ETS83705.1 - 2.4e-10 40.3 2.5 4.9e-10 39.2 1.7 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.16 ETS83705.1 - 8.8 6.0 7.5 3.1 7.4 0.8 2.4 2 0 0 2 2 2 0 Synaptobrevin PTCB-BRCT PF12738.2 ETS83706.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 ETS83706.1 - 0.0024 17.9 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Hamartin PF04388.7 ETS83707.1 - 0.0018 17.0 4.5 0.0025 16.5 3.2 1.1 1 0 0 1 1 1 1 Hamartin protein DUF1501 PF07394.7 ETS83707.1 - 0.013 14.3 3.0 0.021 13.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) OmpH PF03938.9 ETS83707.1 - 0.015 15.2 4.5 0.022 14.7 3.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2461 PF09365.5 ETS83707.1 - 0.03 13.7 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Oxysterol_BP PF01237.13 ETS83707.1 - 4.1 5.7 8.6 29 2.9 6.6 1.7 2 0 0 2 2 2 0 Oxysterol-binding protein GET2 PF08690.5 ETS83707.1 - 5.6 6.1 6.2 1.3 8.1 2.0 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 Nop14 PF04147.7 ETS83708.1 - 0.0028 15.6 0.4 0.0038 15.2 0.3 1.1 1 0 0 1 1 1 1 Nop14-like family Syndecan PF01034.15 ETS83708.1 - 0.045 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain Menin PF05053.8 ETS83708.1 - 0.21 9.7 8.8 0.45 8.6 6.1 1.5 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 ETS83708.1 - 9.6 5.4 24.0 3.2 7.0 9.8 2.3 2 0 0 2 2 2 0 Vta1 like Thioredoxin PF00085.15 ETS83710.1 - 1e-25 89.3 0.1 1.2e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETS83710.1 - 1.1e-08 35.0 0.0 3.1e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS83710.1 - 1.4e-07 31.6 0.3 1.3e-06 28.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 ETS83710.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 ETS83710.1 - 0.00026 20.6 0.3 0.056 13.1 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 ETS83710.1 - 0.00045 19.7 0.4 0.098 12.1 0.1 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 ETS83710.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 ETS83710.1 - 0.0069 16.2 0.0 0.065 13.1 0.0 2.0 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 ETS83710.1 - 0.015 15.3 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.1 ETS83710.1 - 0.041 13.4 0.2 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 ETS83710.1 - 0.047 13.1 0.0 0.086 12.3 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.11 ETS83710.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DSBA PF01323.15 ETS83710.1 - 0.17 11.3 3.0 5.3 6.5 0.3 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain His_Phos_2 PF00328.17 ETS83711.1 - 3.6e-59 200.8 0.0 4.1e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_S19e PF01090.14 ETS83712.1 - 3.2e-58 195.1 0.1 3.6e-58 194.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Zip PF02535.17 ETS83713.1 - 3.3e-52 177.4 11.3 3.8e-52 177.2 7.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3722 PF12519.3 ETS83714.1 - 2.8e-84 282.3 0.0 3.6e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 ETS83714.1 - 6.1e-06 25.7 0.0 0.0019 17.5 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic porin F-box-like PF12937.2 ETS83715.1 - 8.6e-07 28.5 0.6 2.4e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 ETS83715.1 - 0.0018 17.9 0.4 0.0064 16.2 0.3 2.1 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 ETS83715.1 - 0.025 14.2 2.1 0.39 10.4 1.5 2.4 1 1 0 1 1 1 0 F-box domain Acetyltransf_7 PF13508.1 ETS83716.1 - 1.6e-12 47.3 0.1 6.8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS83716.1 - 1.2e-09 38.1 0.0 3.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS83716.1 - 7.5e-05 22.8 0.1 0.00023 21.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS83716.1 - 0.00022 21.1 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS83716.1 - 0.019 14.6 0.0 0.044 13.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Glyco_hydro_72 PF03198.9 ETS83718.1 - 7.1e-112 373.4 0.4 8.8e-112 373.1 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 ETS83718.1 - 0.0001 21.6 0.1 0.29 10.3 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 ETS83718.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MRP-L46 PF11788.3 ETS83719.1 - 2.1e-25 89.5 0.0 4.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 ETS83719.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ABA_GPCR PF12430.3 ETS83720.1 - 2.1e-52 177.1 0.6 4.8e-52 175.9 0.0 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 ETS83720.1 - 5.7e-20 71.1 0.3 2.3e-18 65.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) Ank_2 PF12796.2 ETS83721.1 - 2.3e-52 175.2 1.0 1.4e-15 57.4 0.0 6.7 4 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83721.1 - 4.5e-44 146.1 0.0 4e-08 32.6 0.0 9.8 9 2 0 9 9 9 7 Ankyrin repeat HET PF06985.6 ETS83721.1 - 3.9e-32 111.3 1.0 7.3e-32 110.4 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 ETS83721.1 - 1.4e-30 105.1 7.4 1.8e-05 25.1 0.0 9.3 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83721.1 - 6.6e-30 100.1 8.2 4.9e-05 23.1 0.0 11.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 ETS83721.1 - 3.7e-29 100.0 8.9 3.8e-10 39.6 0.0 8.0 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Bac_rhamnosid PF05592.6 ETS83722.1 - 8.5e-43 146.3 1.5 9.5e-19 66.9 0.0 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS83722.1 - 2.4e-08 33.0 0.7 4.3e-08 32.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 ETS83722.1 - 1.6e-05 23.7 0.1 5.8e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase ELFV_dehydrog PF00208.16 ETS83723.1 - 1e-56 192.2 0.0 1.6e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 ETS83723.1 - 3.5e-21 74.4 0.0 7.1e-16 56.8 0.0 2.4 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 ETS83723.1 - 0.00015 21.3 0.0 0.00049 19.6 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.14 ETS83724.1 - 1.8e-13 49.9 0.0 1.5e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS83724.1 - 4.1e-06 25.3 0.0 6e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS83724.1 - 0.00056 19.0 0.2 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 ETS83724.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II NACHT PF05729.7 ETS83725.1 - 4.5e-08 32.9 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS83725.1 - 9.7e-07 28.9 0.4 8.5e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS83725.1 - 1.2e-06 28.8 0.1 6.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS83725.1 - 2.1e-06 27.8 0.2 0.00012 22.1 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain Ank_2 PF12796.2 ETS83725.1 - 2.5e-06 27.7 0.0 0.0038 17.5 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) DUF2075 PF09848.4 ETS83725.1 - 0.00012 21.1 0.1 0.00048 19.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ank PF00023.25 ETS83725.1 - 0.00079 19.1 0.0 0.53 10.1 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat AAA_17 PF13207.1 ETS83725.1 - 0.0014 19.4 0.0 0.0048 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETS83725.1 - 0.0018 17.1 0.0 0.004 16.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 ETS83725.1 - 0.0021 17.5 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 ETS83725.1 - 0.0032 16.6 0.0 0.0086 15.2 0.0 1.7 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 ETS83725.1 - 0.0039 16.6 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Ank_5 PF13857.1 ETS83725.1 - 0.0039 17.3 0.0 0.13 12.5 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83725.1 - 0.0045 17.0 0.3 7.3 7.1 0.0 4.9 6 0 0 6 6 4 0 Ankyrin repeat AAA_11 PF13086.1 ETS83725.1 - 0.014 14.9 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETS83725.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS83725.1 - 0.018 15.1 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 ETS83725.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 ETS83725.1 - 0.033 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 ETS83725.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 ETS83725.1 - 0.066 12.0 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AP-5_subunit_s1 PF15001.1 ETS83725.1 - 0.092 12.6 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 IncA PF04156.9 ETS83725.1 - 1.2 8.6 4.7 4.1 6.9 0.0 3.1 2 1 0 2 2 2 0 IncA protein F-box PF00646.28 ETS83726.1 - 0.00055 19.5 0.7 0.0018 17.8 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS83726.1 - 0.057 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like SGL PF08450.7 ETS83727.1 - 2.3e-05 23.8 0.1 4.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DDHD PF02862.12 ETS83729.1 - 7.8 6.2 7.2 14 5.4 5.0 1.4 1 1 0 1 1 1 0 DDHD domain GST_N PF02798.15 ETS83730.1 - 3.1e-12 46.5 0.0 7e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS83730.1 - 3.4e-11 43.1 0.0 5.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS83730.1 - 4.5e-10 39.3 0.3 7.9e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS83730.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS83730.1 - 2.2e-07 30.6 0.1 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS83730.1 - 1.7e-06 28.4 0.2 2.4e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2034 PF10356.4 ETS83731.1 - 2.9e-29 101.5 0.0 2e-14 53.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 ETS83731.1 - 4.2e-08 32.9 0.0 7.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 ETS83732.1 - 7.2e-44 149.2 7.2 7.9e-44 149.1 5.0 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 ETS83732.1 - 0.021 14.5 2.1 0.021 14.5 1.5 2.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1640 PF07798.6 ETS83732.1 - 0.022 14.7 1.2 0.025 14.6 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GAS PF13851.1 ETS83732.1 - 0.024 13.8 4.5 1.8 7.7 1.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.1 ETS83732.1 - 0.025 13.7 3.2 0.027 13.6 2.2 1.1 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 ETS83732.1 - 0.13 11.3 3.3 0.14 11.1 2.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 ETS83732.1 - 1 9.4 5.8 4.4 7.4 3.6 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.11 ETS83732.1 - 3.6 7.8 6.0 6.7 6.9 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 IncA PF04156.9 ETS83732.1 - 5.1 6.6 8.2 1.4 8.4 3.1 1.7 2 0 0 2 2 2 0 IncA protein HAD_2 PF13419.1 ETS83733.1 - 5.4e-34 117.9 0.1 7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS83733.1 - 2.9e-08 34.4 0.0 9.1e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS83733.1 - 4.9e-08 32.5 0.0 8.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 ETS83733.1 - 0.00068 19.3 0.0 0.0094 15.5 0.0 2.0 2 0 0 2 2 2 1 Acid Phosphatase HAD PF12710.2 ETS83733.1 - 0.003 17.7 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 5_nucleotid PF05761.9 ETS83733.1 - 0.059 11.8 0.1 0.21 10.0 0.0 1.8 1 1 1 2 2 2 0 5' nucleotidase family KH_1 PF00013.24 ETS83735.1 - 1.2e-28 98.5 7.2 1.3e-07 31.1 0.2 8.0 9 0 0 9 9 9 5 KH domain KH_3 PF13014.1 ETS83735.1 - 9.9e-27 92.0 3.8 4.2e-06 26.2 0.0 7.0 7 0 0 7 7 7 5 KH domain Acetyltransf_1 PF00583.19 ETS83736.1 - 2e-09 37.3 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS83736.1 - 1.1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS83736.1 - 0.00022 21.0 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS83736.1 - 0.00032 20.7 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS83736.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS83736.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pribosyltran PF00156.22 ETS83737.1 - 3.4e-14 52.6 0.1 6.2e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOGCT PF08155.6 ETS83738.1 - 3.6e-29 100.2 2.8 7.2e-29 99.2 2.0 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 ETS83738.1 - 2.1e-25 88.3 0.3 6.2e-25 86.8 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 ETS83738.1 - 4.8e-15 55.5 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS83738.1 - 6.9e-09 35.1 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 ETS83738.1 - 0.0013 17.9 0.1 0.0037 16.4 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RhoGEF PF00621.15 ETS83738.1 - 0.025 14.4 0.4 0.059 13.2 0.3 1.6 1 0 0 1 1 1 0 RhoGEF domain Miro PF08477.8 ETS83738.1 - 0.06 13.8 0.1 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 ETS83738.1 - 0.15 11.8 1.4 10 5.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family IF-2B PF01008.12 ETS83739.1 - 2e-37 128.7 0.0 2.9e-37 128.1 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 ETS83739.1 - 0.0025 17.4 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Methyltransf_33 PF10017.4 ETS83740.1 - 1.5e-33 115.3 0.1 2.7e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 ETS83740.1 - 2.9e-14 53.0 4.4 3.1e-12 46.4 3.1 2.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 ETS83740.1 - 1.2e-06 28.8 0.9 2.7e-06 27.7 0.2 2.0 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 ETS83740.1 - 1.1e-05 25.6 0.0 4.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 ETS83740.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PhnJ PF06007.6 ETS83740.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Peptidase_S28 PF05577.7 ETS83741.1 - 9.5e-48 162.8 0.4 1.9e-47 161.8 0.3 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Pyr_redox_3 PF13738.1 ETS83743.1 - 4.4e-07 30.1 0.0 8.6e-05 22.6 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS83743.1 - 2e-06 27.8 0.0 1.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS83743.1 - 0.0091 16.0 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS83743.1 - 0.041 13.6 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF PF01012.16 ETS83744.1 - 3.9e-39 133.9 0.8 3.9e-39 133.9 0.5 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 ETS83744.1 - 3.6e-36 122.6 1.5 5.9e-36 121.9 0.2 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 ETS83745.1 - 1.2e-34 118.2 0.1 3e-34 117.0 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 ETS83745.1 - 2.2e-08 33.9 0.1 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS83745.1 - 6.6e-07 29.3 0.2 1.5e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Calpain_III PF01067.17 ETS83745.1 - 0.044 13.4 0.1 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Calpain large subunit, domain III ACP_syn_III_C PF08541.5 ETS83745.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ResIII PF04851.10 ETS83747.1 - 1.2e-24 87.2 0.1 2e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS83747.1 - 2.8e-15 55.9 0.1 1.2e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS83747.1 - 4.4e-13 49.0 0.0 1.3e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 ETS83747.1 - 0.00019 20.5 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 ETS83747.1 - 0.053 12.1 0.1 0.11 11.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SNF2_N PF00176.18 ETS83747.1 - 0.095 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 ETS83747.1 - 0.17 12.0 0.6 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PHD_2 PF13831.1 ETS83748.1 - 0.00017 20.8 1.6 0.00036 19.7 1.1 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 ETS83748.1 - 0.00019 21.0 3.0 0.00019 21.0 2.1 2.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 ETS83748.1 - 0.014 15.2 0.8 0.014 15.2 0.6 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 ETS83748.1 - 0.031 13.9 6.1 0.078 12.6 4.3 1.8 1 0 0 1 1 1 0 PHD-finger SAP PF02037.22 ETS83748.1 - 0.079 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 SAP domain zf-RING_2 PF13639.1 ETS83748.1 - 0.091 12.6 19.1 0.1 12.4 5.7 3.6 3 1 1 4 4 4 0 Ring finger domain TGT PF01702.13 ETS83749.1 - 5.5e-88 294.2 0.0 6.6e-88 293.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase GDI PF00996.13 ETS83751.1 - 1.2e-181 603.8 0.0 1.4e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 ETS83751.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 ETS83752.1 - 8.6e-24 83.2 2.6 1.3e-23 82.7 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.13 ETS83754.1 - 2.7e-16 59.2 1.6 2.3e-15 56.1 0.4 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 ETS83754.1 - 1.1e-06 28.6 10.7 1.3e-05 25.2 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS83754.1 - 0.00047 20.3 18.5 0.0015 18.7 4.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 ETS83754.1 - 0.0014 18.7 3.8 0.003 17.6 2.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 ETS83754.1 - 0.015 15.5 16.8 0.051 13.9 4.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type GA PF01468.12 ETS83754.1 - 0.81 9.8 4.4 0.19 11.8 0.5 1.8 2 0 0 2 2 2 0 GA module zf-BED PF02892.10 ETS83754.1 - 2.2 8.1 7.5 1.1 9.0 0.8 2.6 2 0 0 2 2 2 0 BED zinc finger F-box-like_2 PF13013.1 ETS83756.1 - 0.059 13.0 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain DUF500 PF04366.7 ETS83758.1 - 7.8e-29 99.6 0.0 1.5e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Actin PF00022.14 ETS83759.1 - 5.6e-15 54.6 0.0 1.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Actin Fungal_trans PF04082.13 ETS83760.1 - 1.2e-19 70.2 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83760.1 - 2.9e-07 30.2 8.1 5.8e-07 29.3 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E3B PF03376.9 ETS83760.1 - 0.045 13.6 0.3 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus E3B protein Senescence PF06911.7 ETS83761.1 - 1.6e-47 161.5 3.1 2.2e-47 161.0 2.1 1.2 1 0 0 1 1 1 1 Senescence-associated protein Spc97_Spc98 PF04130.8 ETS83762.1 - 7.1e-64 216.0 0.3 8.6e-64 215.7 0.2 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family PA-IL PF07828.7 ETS83762.1 - 0.025 14.3 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 0 PA-IL-like protein SH3_1 PF00018.23 ETS83764.1 - 7.8e-10 37.9 0.1 1.7e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 ETS83764.1 - 1.3e-09 37.3 0.1 2.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 ETS83764.1 - 1.9e-07 30.5 0.2 3.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 ETS83765.1 - 2.5e-17 62.6 0.0 5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 ETS83766.1 - 5.1e-56 187.6 0.2 6.7e-56 187.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.3 ETS83767.1 - 1.3e-76 257.8 0.3 1.7e-76 257.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit MutL_C PF08676.6 ETS83768.1 - 2.1e-22 79.2 1.5 3.3e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 ETS83768.1 - 6.3e-19 67.5 0.0 3.5e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 ETS83768.1 - 1.8e-13 50.2 0.0 8.4e-13 48.1 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 ETS83768.1 - 2.8e-12 46.3 0.0 7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.8 ETS83769.1 - 8.4e-88 293.7 0.0 1.2e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS83769.1 - 2e-06 27.6 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS83769.1 - 0.0003 20.7 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS83769.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 ETS83769.1 - 0.026 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 ETS83769.1 - 0.096 12.3 0.0 0.62 9.6 0.0 2.3 3 0 0 3 3 3 0 Lipase (class 3) VPR PF00522.13 ETS83769.1 - 0.14 11.9 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 VPR/VPX protein Ribosomal_S13_N PF08069.7 ETS83770.1 - 0.025 14.4 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain SAP PF02037.22 ETS83770.1 - 0.098 12.1 0.2 0.21 11.1 0.1 1.7 1 1 0 1 1 1 0 SAP domain Serinc PF03348.10 ETS83771.1 - 8.4e-173 574.9 6.9 1e-172 574.6 4.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF809 PF05663.6 ETS83771.1 - 4.3 7.2 4.8 0.92 9.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF809) MFS_1 PF07690.11 ETS83772.1 - 7.1e-18 64.4 30.8 5.8e-16 58.1 4.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 ETS83772.1 - 9.7e-10 38.1 2.7 1.2e-09 37.8 0.6 2.1 2 0 0 2 2 2 1 Nodulin-like BH3 PF15285.1 ETS83774.1 - 0.023 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Tyrosinase PF00264.15 ETS83775.1 - 9.9e-47 159.9 1.4 1.3e-46 159.5 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2306 PF10067.4 ETS83776.1 - 1.3e-12 47.7 11.3 1.3e-12 47.7 7.9 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) PrgI PF12666.2 ETS83776.1 - 0.01 15.9 1.4 0.01 15.9 1.0 2.7 3 1 1 4 4 4 0 PrgI family protein YqeY PF09424.5 ETS83777.1 - 5.6e-25 87.8 2.4 6.9e-25 87.5 1.7 1.1 1 0 0 1 1 1 1 Yqey-like protein PI3_PI4_kinase PF00454.22 ETS83779.1 - 2.2e-40 138.6 0.0 3e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Flavodoxin_1 PF00258.20 ETS83780.1 - 2.1e-27 95.8 0.0 3.9e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 ETS83780.1 - 4.6e-26 91.6 0.0 7.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 ETS83780.1 - 2e-14 54.0 0.0 9.7e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Asp PF00026.18 ETS83782.1 - 1.1e-13 51.0 2.9 2.2e-13 50.1 2.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TMEM154 PF15102.1 ETS83782.1 - 0.0069 16.0 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 2 TMEM154 protein family Lamp PF01299.12 ETS83782.1 - 0.01 15.0 1.4 0.035 13.2 0.0 2.5 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) EphA2_TM PF14575.1 ETS83782.1 - 0.024 15.0 0.2 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 ETS83782.1 - 0.039 12.7 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2668 PF10873.3 ETS83782.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) F-box-like PF12937.2 ETS83783.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS83783.1 - 2.2e-07 30.3 0.1 3.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 ETS83783.1 - 0.069 12.7 17.5 0.12 11.9 1.5 3.9 3 0 0 3 3 3 0 Ubiquitin interaction motif MFS_1 PF07690.11 ETS83784.1 - 2.5e-31 108.7 32.9 1.4e-28 99.6 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS83784.1 - 0.00036 20.2 5.8 0.052 13.3 0.2 2.8 2 0 0 2 2 2 2 MFS_1 like family FKBP_C PF00254.23 ETS83786.1 - 1.1e-26 92.6 0.0 1.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ABC_tran PF00005.22 ETS83787.1 - 2.2e-50 170.4 0.1 3.6e-28 98.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS83787.1 - 8.5e-32 110.6 22.0 1.1e-18 67.6 4.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS83787.1 - 1e-10 41.2 4.3 0.00044 19.5 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS83787.1 - 1.7e-09 38.0 4.4 0.013 15.4 0.1 4.8 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 ETS83787.1 - 1.4e-08 34.1 0.8 0.0024 17.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 ETS83787.1 - 1.4e-08 34.3 0.0 0.00063 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 ETS83787.1 - 1.4e-07 32.0 1.0 6.1e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS83787.1 - 1.7e-05 24.4 0.0 0.03 13.7 0.0 2.8 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 ETS83787.1 - 2.7e-05 23.4 0.1 0.044 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 ETS83787.1 - 6.2e-05 22.5 0.1 0.2 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain T2SE PF00437.15 ETS83787.1 - 0.00036 19.5 1.0 0.49 9.2 0.0 2.9 3 1 0 3 3 3 2 Type II/IV secretion system protein Dynamin_N PF00350.18 ETS83787.1 - 0.00041 20.2 1.7 0.77 9.5 0.0 2.7 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 ETS83787.1 - 0.00049 20.0 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 ETS83787.1 - 0.00054 19.8 1.5 1.7 8.6 0.6 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 ETS83787.1 - 0.00068 19.3 0.3 0.088 12.5 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 ETS83787.1 - 0.00087 18.9 0.2 0.41 10.4 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 ETS83787.1 - 0.00091 19.2 1.2 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 ETS83787.1 - 0.00096 19.9 0.0 1.3 9.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETS83787.1 - 0.0011 19.4 0.5 0.47 10.9 0.1 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 ETS83787.1 - 0.0024 18.0 0.5 4.9 7.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 ETS83787.1 - 0.0026 17.6 0.1 0.0026 17.6 0.1 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 ETS83787.1 - 0.0045 16.8 0.0 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS83787.1 - 0.0062 16.8 0.0 6.5 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 ETS83787.1 - 0.012 15.0 0.7 4.7 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ETS83787.1 - 0.018 14.9 0.5 3.7 7.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 ETS83787.1 - 0.027 14.6 1.1 9.3 6.4 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 ETS83787.1 - 0.028 14.1 0.7 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 ETS83787.1 - 0.032 13.0 0.2 2.7 6.7 0.1 2.9 2 2 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 ETS83787.1 - 0.034 13.6 0.1 5.7 6.3 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 ETS83787.1 - 0.049 13.3 0.2 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_30 PF13604.1 ETS83787.1 - 0.051 13.1 0.8 5.5 6.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain DEAD PF00270.24 ETS83787.1 - 0.055 12.9 0.1 2.6 7.5 0.1 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase Mis12 PF05859.7 ETS83787.1 - 0.055 13.2 0.8 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Mis12 protein Pox_A32 PF04665.7 ETS83787.1 - 0.083 12.1 1.3 1.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 ETS83787.1 - 0.096 11.7 0.3 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DAP3 PF10236.4 ETS83787.1 - 0.11 11.4 0.6 9.6 5.0 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.9 ETS83787.1 - 0.12 12.1 0.6 27 4.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS83787.1 - 0.13 12.4 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 ETS83787.1 - 0.19 11.2 1.5 8.6 5.8 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein His_Phos_2 PF00328.17 ETS83788.1 - 8.4e-124 413.3 0.9 1.1e-123 412.9 0.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 ETS83788.1 - 7.8e-08 32.0 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 ETS83788.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Utp21 PF04192.7 ETS83789.1 - 1.5e-85 286.0 1.2 2.1e-85 285.5 0.8 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 ETS83789.1 - 4.4e-21 73.9 24.8 4.9e-05 23.0 0.2 8.8 11 0 0 11 11 11 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS83789.1 - 0.00022 19.6 0.0 0.00038 18.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 ETS83789.1 - 0.0003 19.0 0.0 2.3 6.2 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 MFS_1 PF07690.11 ETS83790.1 - 3.8e-12 45.6 12.1 4.9e-12 45.2 8.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83790.1 - 0.00046 18.8 2.0 0.00064 18.4 1.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83791.1 - 1.1e-14 53.8 28.8 1.4e-14 53.5 18.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.16 ETS83791.1 - 0.00031 19.9 2.5 0.0078 15.3 1.7 2.2 1 1 0 1 1 1 1 Cation efflux family Ras PF00071.17 ETS83792.1 - 3.2e-40 137.1 0.0 6e-38 129.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETS83792.1 - 6.3e-18 65.4 0.0 8.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS83792.1 - 9.4e-11 41.2 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 ETS83792.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS83792.1 - 0.0043 16.3 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 ETS83792.1 - 0.0098 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 ETS83792.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS83792.1 - 0.087 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS83792.1 - 0.13 12.1 0.3 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 ETS83792.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Dynamin family DUF588 PF04535.7 ETS83793.1 - 0.035 13.6 0.5 0.054 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) SAP PF02037.22 ETS83794.1 - 2.3e-14 52.4 1.2 4e-14 51.6 0.8 1.4 1 0 0 1 1 1 1 SAP domain Vac7 PF12751.2 ETS83795.1 - 0.42 9.3 9.5 0.75 8.5 6.6 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 GATA PF00320.22 ETS83796.1 - 6.3e-31 105.4 18.5 1.4e-16 59.5 3.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 ETS83796.1 - 5.4e-07 28.8 3.3 0.011 15.0 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 ETS83796.1 - 0.0055 16.6 1.6 1.9 8.5 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain ArfGap PF01412.13 ETS83796.1 - 0.0058 16.3 3.5 0.54 10.0 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf RRN7 PF11781.3 ETS83796.1 - 0.0088 15.5 7.5 0.38 10.2 0.6 2.4 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 ETS83796.1 - 0.02 14.0 8.9 0.36 10.1 0.6 2.9 2 2 0 2 2 2 0 zinc-ribbon domain NMD3 PF04981.8 ETS83796.1 - 0.029 13.4 0.7 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 NMD3 family Auto_anti-p27 PF06677.7 ETS83796.1 - 0.057 13.1 3.6 4.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.14 ETS83796.1 - 0.19 11.4 3.0 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C2H2_3 PF13878.1 ETS83796.1 - 0.19 11.2 11.2 4.2 7.0 0.3 4.4 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-CHY PF05495.7 ETS83796.1 - 0.21 11.7 1.9 4.3 7.5 0.1 2.5 2 0 0 2 2 2 0 CHY zinc finger DZR PF12773.2 ETS83796.1 - 0.26 11.1 17.7 1.6 8.5 1.5 3.5 1 1 1 2 2 2 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 ETS83796.1 - 0.47 10.1 2.3 7.6 6.3 0.1 2.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_L32p PF01783.18 ETS83796.1 - 0.55 10.4 8.9 7 6.9 1.5 4.0 2 2 0 2 2 2 0 Ribosomal L32p protein family eIF-5_eIF-2B PF01873.12 ETS83796.1 - 0.55 9.8 5.9 2.4 7.8 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.2 ETS83796.1 - 0.63 9.8 6.9 1.6 8.6 0.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 ETS83796.1 - 0.79 9.4 15.1 0.12 12.0 0.9 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain FAM163 PF15069.1 ETS83796.1 - 4.1 7.9 6.9 39 4.8 0.9 3.3 2 1 1 3 3 3 0 FAM163 family zf-Sec23_Sec24 PF04810.10 ETS83796.1 - 5.1 6.7 12.8 0.08 12.5 0.4 2.8 3 0 0 3 3 2 0 Sec23/Sec24 zinc finger COPI_assoc PF08507.5 ETS83797.1 - 1.2e-38 131.9 7.1 1.3e-38 131.7 4.9 1.0 1 0 0 1 1 1 1 COPI associated protein Bax1-I PF01027.15 ETS83797.1 - 0.074 12.6 7.2 0.078 12.5 5.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 UCR_Fe-S_N PF10399.4 ETS83797.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ycf66_N PF07444.6 ETS83797.1 - 0.18 11.5 3.5 0.19 11.4 1.7 1.5 1 1 0 1 1 1 0 Ycf66 protein N-terminus Neurensin PF14927.1 ETS83797.1 - 4.7 6.6 6.5 5 6.5 3.4 1.7 1 1 1 2 2 2 0 Neurensin DUF3112 PF11309.3 ETS83798.1 - 2.6e-38 131.3 3.7 2.6e-38 131.3 2.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) Metallophos PF00149.23 ETS83799.1 - 4e-44 150.4 0.9 4.9e-44 150.1 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 ETS83800.1 - 1.3e-05 24.7 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS83801.1 - 0.018 14.7 0.5 0.043 13.4 0.4 1.7 1 0 0 1 1 1 0 F-box domain zf-CCHC PF00098.18 ETS83801.1 - 0.31 11.0 3.5 0.84 9.6 2.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Radical_SAM PF04055.16 ETS83802.1 - 3.9e-26 92.1 0.1 1.1e-25 90.6 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 ETS83802.1 - 1e-22 79.9 0.0 2.6e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 ETS83802.1 - 6.3e-10 39.2 0.0 1.9e-08 34.4 0.1 2.9 3 1 0 3 3 3 1 Flavodoxin MAS20 PF02064.10 ETS83803.1 - 5.5e-17 61.8 0.1 1.3e-16 60.5 0.1 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor Vps51 PF08700.6 ETS83804.1 - 5.6e-17 61.3 1.8 5.6e-17 61.3 1.2 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 ETS83804.1 - 0.00017 21.4 0.7 0.016 15.0 0.0 3.1 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_B PF00052.13 ETS83804.1 - 0.041 13.5 0.3 0.089 12.3 0.2 1.6 1 0 0 1 1 1 0 Laminin B (Domain IV) Atg14 PF10186.4 ETS83804.1 - 0.6 8.9 12.9 0.033 13.1 3.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2383 PF09537.5 ETS83804.1 - 0.69 10.1 6.9 1.9 8.7 1.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) DUF2313 PF10076.4 ETS83805.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) HgmA PF04209.8 ETS83806.1 - 3.2e-112 375.0 0.0 4e-112 374.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ABM PF03992.11 ETS83807.1 - 9.4e-07 28.7 0.6 0.053 13.5 0.0 2.7 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HET PF06985.6 ETS83808.1 - 6e-26 91.2 0.0 1.3e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MCM PF00493.18 ETS83810.1 - 1.1e-129 431.9 1.1 1.7e-129 431.3 0.8 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS83810.1 - 1.4e-12 48.1 0.0 1.1e-11 45.2 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS83810.1 - 2.6e-07 30.0 0.0 3.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS83810.1 - 0.0022 17.6 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS83810.1 - 0.0091 15.4 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Sec7 PF01369.15 ETS83811.1 - 2.6e-59 200.0 0.0 5.3e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 ETS83811.1 - 6.2e-21 74.5 0.2 2.1e-12 46.8 0.0 3.5 3 0 0 3 3 3 3 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 ETS83812.1 - 3.8e-121 403.3 0.0 6.9e-121 402.5 0.0 1.4 1 0 0 1 1 1 1 Anp1 Rad54_N PF08658.5 ETS83812.1 - 0.0082 15.9 4.0 0.015 15.0 2.7 1.4 1 0 0 1 1 1 1 Rad54 N terminal CENP-N PF05238.8 ETS83812.1 - 0.034 13.2 3.0 0.054 12.5 2.1 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF788 PF05620.6 ETS83812.1 - 0.16 11.7 1.2 0.39 10.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF1510 PF07423.6 ETS83812.1 - 0.83 8.9 18.3 9.9 5.4 11.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2146 PF10220.4 ETS83812.1 - 1.2 7.0 6.7 1.6 6.6 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) HSP70 PF00012.15 ETS83812.1 - 6.4 4.5 11.3 12 3.6 7.9 1.3 1 0 0 1 1 1 0 Hsp70 protein Ycf1 PF05758.7 ETS83812.1 - 6.6 4.3 9.2 8.7 3.9 6.4 1.1 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.11 ETS83813.1 - 1.6e-39 135.6 40.6 1.7e-38 132.2 28.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83813.1 - 8.1e-16 57.6 9.6 8.1e-16 57.6 6.7 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 ETS83813.1 - 9.8e-07 27.3 13.7 1.2e-06 27.0 9.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 ETS83813.1 - 4.6e-05 22.3 0.6 4.6e-05 22.3 0.4 2.3 2 0 0 2 2 2 1 BT1 family OATP PF03137.15 ETS83813.1 - 9.6 4.1 12.0 0.12 10.4 0.7 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 ETS83816.1 - 8.1e-20 71.1 0.2 1.4e-19 70.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS83816.1 - 7.5e-13 48.1 5.9 2.1e-06 26.9 0.0 2.7 1 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS83816.1 - 1.8e-07 30.3 7.1 5.6e-06 25.4 0.9 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS83816.1 - 2.6e-07 30.5 0.4 7.1e-07 29.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS83816.1 - 2.7e-07 29.4 0.7 0.0011 17.5 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 ETS83816.1 - 2.1e-05 24.8 0.7 0.0048 17.2 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS83816.1 - 2.2e-05 24.4 0.4 9.3e-05 22.3 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS83816.1 - 2.6e-05 23.0 3.6 0.0016 17.1 0.1 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 ETS83816.1 - 2.7e-05 23.4 1.5 0.028 13.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 ETS83816.1 - 3.4e-05 23.6 3.4 4.8e-05 23.1 0.1 2.6 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS83816.1 - 0.00027 21.0 0.0 0.00056 20.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS83816.1 - 0.00049 19.3 0.7 0.0009 18.4 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS83816.1 - 0.00062 18.7 0.4 0.00062 18.7 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS83816.1 - 0.0031 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETS83816.1 - 0.0032 16.5 0.4 0.0078 15.3 0.2 1.7 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 ETS83816.1 - 0.004 16.5 0.2 0.0096 15.3 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 ETS83816.1 - 0.0053 15.7 3.1 0.14 11.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS83816.1 - 0.0067 16.1 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 ETS83816.1 - 0.077 11.8 0.0 0.18 10.6 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 ETS83816.1 - 0.081 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans PF04082.13 ETS83817.1 - 2.1e-27 95.6 0.1 3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83817.1 - 2.9e-07 30.2 12.6 5.2e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 ETS83818.1 - 2e-14 53.5 0.0 5.8e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 ETS83818.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain zf-RING_5 PF14634.1 ETS83819.1 - 4.6e-09 35.8 7.8 8e-09 35.0 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS83819.1 - 1.4e-05 25.0 4.6 2.9e-05 24.0 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS83819.1 - 2.1e-05 24.2 4.8 4.4e-05 23.2 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 ETS83819.1 - 0.00019 21.2 3.4 0.00036 20.3 2.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 ETS83819.1 - 0.00052 19.6 6.6 0.0011 18.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS83819.1 - 0.00073 19.1 8.1 0.0014 18.2 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 ETS83819.1 - 0.0087 15.8 2.5 0.017 14.9 1.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 ETS83819.1 - 0.025 14.1 4.5 0.047 13.2 3.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 ETS83819.1 - 0.028 14.1 3.1 0.063 13.0 2.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Mito_carr PF00153.22 ETS83819.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial carrier protein Tropomyosin_1 PF12718.2 ETS83819.1 - 0.066 13.0 7.4 0.1 12.4 5.1 1.2 1 0 0 1 1 1 0 Tropomyosin like DZR PF12773.2 ETS83819.1 - 0.075 12.8 2.6 0.17 11.7 1.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.9 ETS83819.1 - 0.2 11.1 5.0 0.45 10.0 3.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger Fzo_mitofusin PF04799.8 ETS83819.1 - 0.22 10.9 4.3 0.32 10.3 3.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region Nudix_N_2 PF14803.1 ETS83819.1 - 0.41 10.3 3.2 1.3 8.7 2.2 1.9 1 1 0 1 1 1 0 Nudix N-terminal zf-rbx1 PF12678.2 ETS83819.1 - 0.86 9.7 4.8 1.6 8.8 3.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 ETS83819.1 - 1.1 8.9 4.2 2.4 7.8 2.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 ETS83819.1 - 5.8 6.8 8.6 16 5.4 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) His_Phos_2 PF00328.17 ETS83820.1 - 0.046 13.0 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) GDA1_CD39 PF01150.12 ETS83821.1 - 6.4e-110 367.6 0.0 8.8e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.12 ETS83821.1 - 0.086 12.8 1.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 E2 (early) protein, C terminal DUF775 PF05603.7 ETS83823.1 - 1.5e-42 145.4 0.0 2.9e-42 144.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 ETS83824.1 - 7.8e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 ETS83825.1 - 1.3e-36 125.7 0.0 1.5e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 ETS83826.1 - 1.6e-102 343.0 0.0 1.7e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 ETS83827.1 - 7.5e-15 54.5 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF782 PF05614.6 ETS83827.1 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) BCA_ABC_TP_C PF12399.3 ETS83827.1 - 0.2 11.3 1.0 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter zf-C3HC4_3 PF13920.1 ETS83828.1 - 1.3e-07 31.1 14.5 2.3e-07 30.3 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 ETS83828.1 - 6.9 6.9 9.5 15 5.8 6.6 1.5 1 0 0 1 1 1 0 FAM24 family RNase_PH PF01138.16 ETS83829.1 - 3.6e-27 95.2 0.0 6.8e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 adh_short PF00106.20 ETS83830.1 - 6.4e-36 123.7 0.1 1.6e-35 122.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS83830.1 - 1.8e-13 50.5 0.0 3.4e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS83830.1 - 8.5e-13 48.6 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 ETS83830.1 - 0.00033 20.3 0.1 0.005 16.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ETS83830.1 - 0.024 13.5 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cytochrom_B_N_2 PF13631.1 ETS83831.1 - 0.038 13.7 0.2 0.098 12.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Lactococcin PF04369.8 ETS83831.1 - 0.11 12.4 0.1 8.8 6.3 0.0 2.9 2 1 1 3 3 3 0 Lactococcin-like family PAN_4 PF14295.1 ETS83832.1 - 0.29 10.8 6.2 0.61 9.8 4.3 1.5 1 0 0 1 1 1 0 PAN domain FAD_binding_4 PF01565.18 ETS83834.1 - 3.8e-29 100.9 0.6 6.6e-29 100.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Lipase_GDSL_2 PF13472.1 ETS83836.1 - 7.4e-13 49.0 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS83836.1 - 3.4e-10 40.1 0.0 4.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ETS83836.1 - 0.0043 16.7 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 ETS83837.1 - 2.4e-31 108.7 36.5 2.4e-31 108.7 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.24 ETS83838.1 - 3e-51 173.0 0.0 6e-43 146.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS83838.1 - 2.1e-06 27.8 0.0 0.02 14.8 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETS83838.1 - 2.5e-06 27.3 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ETS83838.1 - 8.5e-06 25.5 0.1 0.021 14.5 0.0 3.8 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS83838.1 - 4.4e-05 23.6 0.2 2.3 8.3 0.0 4.2 3 2 1 4 4 3 1 AAA domain RNA_helicase PF00910.17 ETS83838.1 - 0.00036 20.6 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 ETS83838.1 - 0.00064 19.7 0.0 0.23 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 ETS83838.1 - 0.00079 19.1 0.5 0.035 13.7 0.0 2.9 2 1 0 2 2 2 1 NACHT domain RuvB_N PF05496.7 ETS83838.1 - 0.001 18.2 0.0 0.0027 16.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 ETS83838.1 - 0.0011 18.8 0.0 0.023 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 ETS83838.1 - 0.0014 17.6 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETS83838.1 - 0.0014 19.4 0.0 1.8 9.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 ETS83838.1 - 0.0014 17.8 0.1 0.22 10.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 ETS83838.1 - 0.0014 17.7 0.0 1.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.18 ETS83838.1 - 0.0015 18.4 0.1 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 ETS83838.1 - 0.0034 17.0 0.0 0.24 11.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 ETS83838.1 - 0.0045 16.8 0.0 4.9 7.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 ETS83838.1 - 0.0069 16.1 0.1 4.6 6.8 0.0 3.2 2 2 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 ETS83838.1 - 0.0093 15.3 3.0 13 5.1 0.1 3.8 2 2 2 4 4 4 0 AAA domain CDC48_N PF02359.13 ETS83838.1 - 0.012 15.5 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain KaiC PF06745.8 ETS83838.1 - 0.026 13.6 0.8 13 4.8 0.1 3.2 2 1 1 3 3 3 0 KaiC TIP49 PF06068.8 ETS83838.1 - 0.085 11.5 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus DAP3 PF10236.4 ETS83838.1 - 0.24 10.3 0.0 0.54 9.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.10 ETS83838.1 - 0.25 9.9 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Ras PF00071.17 ETS83840.1 - 6.9e-65 217.3 0.0 8.3e-65 217.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS83840.1 - 3.8e-19 69.3 0.0 5.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS83840.1 - 3.1e-13 49.3 0.0 3.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS83840.1 - 3.2e-06 26.7 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 ETS83840.1 - 1.3e-05 24.4 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS83840.1 - 0.0057 16.5 0.0 0.008 16.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 ETS83840.1 - 0.0073 15.5 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 ETS83840.1 - 0.026 14.7 0.0 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 ETS83840.1 - 0.067 12.4 0.0 0.31 10.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 ETS83840.1 - 0.088 11.4 0.4 11 4.6 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 ETS83840.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 ETS83841.1 - 5.6e-88 294.5 0.0 8.9e-88 293.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 ETS83841.1 - 0.16 10.7 0.1 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FA_hydroxylase PF04116.8 ETS83842.1 - 9.9e-15 54.9 19.5 9.9e-15 54.9 13.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 ETS83843.1 - 7e-27 93.0 0.0 8.6e-27 92.7 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Amidohydro_1 PF01979.15 ETS83844.1 - 2.1e-22 80.2 0.0 3.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS83844.1 - 6.7e-15 55.8 0.3 2.8e-07 30.8 0.0 2.6 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 ETS83844.1 - 7.3e-10 38.6 1.0 8.7e-08 31.7 0.2 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS83844.1 - 9e-08 31.8 0.1 5.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase bZIP_1 PF00170.16 ETS83845.1 - 5.7e-07 29.3 9.8 2.1e-06 27.5 6.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor Adeno_PIX PF03955.9 ETS83845.1 - 0.0069 16.9 0.4 0.016 15.6 0.1 1.7 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) bZIP_2 PF07716.10 ETS83845.1 - 0.0093 15.7 10.5 0.91 9.4 4.5 2.3 1 1 1 2 2 2 2 Basic region leucine zipper MbeD_MobD PF04899.7 ETS83845.1 - 0.2 11.5 2.4 0.38 10.7 1.6 1.4 1 0 0 1 1 1 0 MbeD/MobD like dsrm PF00035.20 ETS83845.1 - 0.41 11.2 2.0 0.43 11.1 0.3 1.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif Actin PF00022.14 ETS83846.1 - 7.2e-54 182.7 0.0 8.9e-33 113.2 0.0 2.1 2 0 0 2 2 2 2 Actin YL1_C PF08265.6 ETS83847.1 - 6.1e-15 54.4 0.1 1.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 ETS83848.1 - 1e-18 67.5 11.5 1.2e-18 67.3 8.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 ETS83848.1 - 0.78 9.4 8.4 0.075 12.7 2.0 2.1 2 1 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 ETS83849.1 - 4.3e-38 130.1 0.2 4.9e-38 129.9 0.2 1.0 1 0 0 1 1 1 1 Profilin Longin PF13774.1 ETS83851.1 - 2.2e-14 52.7 0.0 3.8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 ETS83851.1 - 3.5e-14 52.1 0.3 5.2e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 ETS83851.1 - 0.02 14.6 0.3 0.037 13.7 0.2 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Sec63 PF02889.11 ETS83852.1 - 2.5e-154 513.1 0.0 2.2e-95 319.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 ETS83852.1 - 1.7e-54 183.8 0.2 2.5e-28 98.7 0.1 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS83852.1 - 3.1e-17 62.2 0.0 1.1e-06 28.4 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 ETS83852.1 - 3.7e-16 59.4 0.0 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS83852.1 - 7.3e-09 35.8 0.2 0.018 15.1 0.0 4.1 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS83852.1 - 2.6e-06 27.0 0.2 0.012 15.3 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 ETS83852.1 - 1.9e-05 24.3 0.1 0.11 12.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 ETS83852.1 - 6.6e-05 22.4 0.0 3.1 7.1 0.0 4.6 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA PF00004.24 ETS83852.1 - 0.0016 18.6 1.2 0.87 9.7 0.0 4.6 6 1 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 ETS83852.1 - 0.026 13.9 0.0 4.8 6.6 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 ETS83852.1 - 0.026 13.4 0.0 0.91 8.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETS83852.1 - 0.043 12.9 0.0 1.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 ETS83852.1 - 0.079 13.2 0.0 0.39 11.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS83852.1 - 0.09 12.1 0.1 37 3.6 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain Yip1 PF04893.12 ETS83853.1 - 1.1e-12 47.7 16.9 1.5e-12 47.3 11.5 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 ETS83853.1 - 4.2 6.9 13.3 8.7 5.9 9.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PAS_3 PF08447.6 ETS83854.1 - 1.9e-13 50.3 0.0 2.5e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 ETS83854.1 - 1.1e-10 41.8 0.0 1.8e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 ETS83854.1 - 4.5e-09 36.0 0.0 9.9e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 ETS83854.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 ETS83854.1 - 0.00019 21.4 0.2 0.0029 17.6 0.0 2.7 3 0 0 3 3 3 1 PAS fold WD40 PF00400.27 ETS83855.1 - 1e-14 53.7 18.3 5.4e-06 26.0 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat RNA_pol_I_TF PF04090.7 ETS83856.1 - 1.6e-11 43.8 0.0 6.2e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ETC_C1_NDUFA5 PF04716.9 ETS83857.1 - 1.3e-20 72.6 2.7 5.6e-20 70.6 0.2 2.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region Ank_2 PF12796.2 ETS83858.1 - 7.9e-70 231.2 12.8 1.7e-21 76.3 0.3 7.0 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83858.1 - 2e-61 200.8 17.4 5.4e-07 29.1 0.1 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 ETS83858.1 - 7.9e-50 166.4 8.1 5.5e-10 39.4 0.1 9.4 3 1 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83858.1 - 1.8e-43 142.2 11.5 9.5e-05 22.2 0.0 11.3 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 ETS83858.1 - 1.2e-41 139.7 18.7 2.2e-09 37.2 0.1 9.7 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Sugar_tr PF00083.19 ETS83859.1 - 7.7e-68 229.1 24.9 9e-68 228.8 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83859.1 - 1.1e-17 63.8 30.7 1.3e-10 40.5 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS83859.1 - 3.2e-05 22.5 30.2 0.00071 18.0 6.0 3.9 2 2 2 4 4 4 3 MFS/sugar transport protein DUF3278 PF11683.3 ETS83859.1 - 4.7 7.2 5.8 12 5.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Zn_clus PF00172.13 ETS83860.1 - 4.8e-09 35.9 7.8 4.8e-09 35.9 5.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 ETS83861.1 - 6.5e-42 143.0 0.0 1.4e-20 73.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS83861.1 - 1.4e-32 113.2 29.6 8e-27 94.3 7.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS83861.1 - 3.7e-11 42.6 0.0 0.0012 18.1 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 ETS83861.1 - 3.4e-07 29.8 1.4 0.03 13.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 ETS83861.1 - 4.2e-07 30.2 2.4 0.019 14.9 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS83861.1 - 5.1e-07 29.8 1.8 0.00044 20.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS83861.1 - 9.1e-05 22.6 1.1 0.036 14.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 ETS83861.1 - 0.00036 20.4 0.9 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 ETS83861.1 - 0.00064 19.5 1.0 0.13 12.2 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 ETS83861.1 - 0.0011 19.4 0.1 2.4 8.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 ETS83861.1 - 0.0012 18.0 0.7 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 ETS83861.1 - 0.0031 16.4 0.4 0.015 14.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain DUF3514 PF12027.3 ETS83861.1 - 0.0042 16.3 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3514) TrwB_AAD_bind PF10412.4 ETS83861.1 - 0.0075 14.9 0.2 0.65 8.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 ETS83861.1 - 0.0081 16.1 0.1 2 8.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 ETS83861.1 - 0.0092 15.6 0.8 0.6 9.7 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 ETS83861.1 - 0.016 15.4 0.3 2.2 8.6 0.1 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS83861.1 - 0.019 14.4 0.5 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 ETS83861.1 - 0.023 14.9 0.7 4.7 7.4 0.0 3.7 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS83861.1 - 0.024 14.2 0.1 0.079 12.5 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 ETS83861.1 - 0.026 15.3 0.1 2 9.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS83861.1 - 0.037 13.1 0.3 1.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 ETS83861.1 - 0.039 12.8 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PIF1 PF05970.9 ETS83861.1 - 0.04 12.8 0.6 0.3 9.9 0.1 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_29 PF13555.1 ETS83861.1 - 0.051 13.1 3.4 5.6 6.5 0.3 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 ETS83861.1 - 0.063 12.1 2.9 0.21 10.4 0.2 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 ETS83861.1 - 0.067 12.6 2.4 2.4 7.5 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 ETS83861.1 - 0.068 12.9 1.7 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 ETS83861.1 - 0.12 12.5 0.1 3.3 7.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF3328 PF11807.3 ETS83862.1 - 3.9e-06 26.7 0.0 4.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ligase_CoA PF00549.14 ETS83862.1 - 0.0085 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase DUF3328 PF11807.3 ETS83863.1 - 6.8e-36 123.9 0.0 9.2e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cmc1 PF08583.5 ETS83863.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Tetraspannin PF00335.15 ETS83863.1 - 2.7 7.1 4.6 20 4.3 3.2 2.0 1 1 0 1 1 1 0 Tetraspanin family HET PF06985.6 ETS83865.1 - 1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 ETS83867.1 - 9.5e-25 86.6 0.7 1.4e-24 86.1 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS83867.1 - 0.0034 17.2 0.0 0.0088 15.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like USP8_dimer PF08969.6 ETS83867.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain BBE PF08031.7 ETS83868.1 - 0.0042 16.9 0.1 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 ETS83869.1 - 1.2e-16 61.0 0.3 1.9e-16 60.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS83869.1 - 7.4e-07 29.0 0.1 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS83869.1 - 0.0015 18.0 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GST_C PF00043.20 ETS83871.1 - 1.3e-09 37.9 0.0 3.9e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS83871.1 - 3.8e-05 23.4 0.6 7.8e-05 22.4 0.4 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS83871.1 - 0.011 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.19 ETS83872.1 - 1.8e-05 24.6 0.2 0.00013 21.9 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS83872.1 - 0.00035 20.6 0.0 0.0062 16.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_19 PF14559.1 ETS83873.1 - 0.00055 20.2 0.8 0.89 9.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS83873.1 - 0.0018 17.9 0.0 0.085 12.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS83873.1 - 0.0072 16.9 1.5 1.1 10.0 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS83873.1 - 0.024 14.5 0.9 0.6 10.0 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 ETS83873.1 - 0.046 13.6 0.1 0.23 11.3 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 ETS83873.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETS83873.1 - 0.068 13.8 4.1 57 4.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS83874.1 - 8.2e-30 103.7 13.8 8.2e-30 103.7 9.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_6 PF08030.7 ETS83875.1 - 2e-18 66.7 0.0 3.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS83875.1 - 3.6e-11 42.8 0.0 6.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 ETS83875.1 - 7.8e-11 42.1 10.6 1.7e-10 41.0 7.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 ETS83875.1 - 0.00078 19.9 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PGG PF13962.1 ETS83875.1 - 0.079 12.5 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function COX2_TM PF02790.10 ETS83875.1 - 1.3 9.0 6.1 2.8 7.9 0.0 3.2 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain MFS_1 PF07690.11 ETS83876.1 - 1.6e-15 56.6 39.8 3.4e-12 45.7 9.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83876.1 - 1.7e-06 26.9 20.7 1.7e-06 26.9 14.3 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS83877.1 - 3.6e-31 108.1 60.9 3.6e-31 108.1 42.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS83877.1 - 3.6e-12 45.2 29.7 6.5e-12 44.4 20.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS83877.1 - 1.1e-08 34.0 9.8 1.1e-08 34.0 6.8 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS83877.1 - 0.16 10.0 11.6 0.5 8.3 1.8 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.6 ETS83879.1 - 2e-17 63.6 0.3 4.5e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.9 ETS83880.1 - 1.8e-102 343.4 21.4 2.3e-102 343.1 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Myc_target_1 PF15179.1 ETS83882.1 - 0.00098 18.7 0.7 0.0017 18.0 0.5 1.3 1 0 0 1 1 1 1 Myc target protein 1 Colicin_V PF02674.11 ETS83882.1 - 0.038 13.8 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF2453 PF10507.4 ETS83882.1 - 0.041 13.6 0.1 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) Adeno_E3_CR2 PF02439.10 ETS83882.1 - 0.093 12.2 11.4 0.3 10.6 7.9 1.8 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Ctr PF04145.10 ETS83882.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family Amnionless PF14828.1 ETS83882.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.5 ETS83882.1 - 0.15 11.4 0.2 0.15 11.4 0.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 ETS83882.1 - 0.93 9.0 3.8 2.6 7.6 2.6 1.8 1 1 0 1 1 1 0 Podoplanin Ribosomal_S26e PF01283.14 ETS83883.1 - 0.0029 17.8 0.0 0.0061 16.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S26e Methyltransf_23 PF13489.1 ETS83884.1 - 4.9e-07 29.5 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS83884.1 - 0.006 16.1 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 ETS83884.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 ETS83885.1 - 1.6e-05 24.7 4.6 1.6e-05 24.7 3.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 ETS83886.1 - 1.4e-14 54.6 0.5 3.3e-14 53.3 0.1 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS83886.1 - 1.5e-09 38.0 0.0 2.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS83887.1 - 3.3e-18 66.2 0.0 1.2e-17 64.4 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS83887.1 - 1.9e-13 50.5 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NDUFA12 PF05071.11 ETS83887.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 AMP-binding PF00501.23 ETS83888.1 - 3.6e-154 513.1 0.0 3.9e-78 262.7 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 ETS83888.1 - 3.6e-50 170.5 0.0 1.7e-32 112.5 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 ETS83888.1 - 2.8e-22 78.7 0.1 6.9e-11 42.2 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site ATP-synt_C PF00137.16 ETS83888.1 - 0.15 11.9 0.8 0.33 10.8 0.5 1.5 1 0 0 1 1 1 0 ATP synthase subunit C DNase_NucA_NucB PF14040.1 ETS83891.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB p450 PF00067.17 ETS83892.1 - 1.1e-72 245.1 0.0 1.4e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 ETS83893.1 - 3.8e-72 242.6 0.0 5.6e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 ETS83893.1 - 8.8e-25 86.7 0.0 1.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 ETS83893.1 - 4.6e-15 55.2 0.0 1.3e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 ETS83893.1 - 1.3e-06 28.3 10.0 2.4e-06 27.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS83893.1 - 0.00019 20.9 10.1 0.00039 20.0 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS83893.1 - 0.00032 20.2 7.6 0.00057 19.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 ETS83893.1 - 0.0059 16.4 10.9 0.011 15.4 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.1 ETS83893.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain zf-RING_5 PF14634.1 ETS83893.1 - 0.43 10.3 9.7 1.9 8.2 6.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain SQS_PSY PF00494.14 ETS83894.1 - 7.9e-56 189.2 0.0 1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LDB19 PF13002.2 ETS83895.1 - 1.7e-38 132.0 0.3 1.3e-37 129.1 0.2 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 ETS83895.1 - 0.0013 18.6 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF2235 PF09994.4 ETS83897.1 - 4.6e-68 229.5 0.0 5.9e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 ETS83897.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 ETS83898.1 - 9.9e-15 54.0 25.7 1.5e-14 53.5 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF592 PF04574.8 ETS83898.1 - 0.17 11.4 0.2 0.54 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF592) adh_short PF00106.20 ETS83899.1 - 5.1e-18 65.5 8.3 1.9e-16 60.4 5.7 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS83899.1 - 2.1e-11 44.0 0.2 5.2e-11 42.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS83899.1 - 4.8e-10 39.3 0.4 4.8e-10 39.3 0.3 2.6 2 1 0 2 2 2 1 KR domain Pyr_redox PF00070.22 ETS83899.1 - 0.015 15.7 0.2 0.026 14.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS83899.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 ETS83899.1 - 0.032 12.9 0.1 0.056 12.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 ETS83899.1 - 0.074 13.0 0.5 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding DUF2231 PF09990.4 ETS83902.1 - 0.016 15.5 0.6 0.02 15.2 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) TRP PF06011.7 ETS83902.1 - 0.032 12.8 4.1 0.034 12.7 2.8 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ni_hydr_CYTB PF01292.15 ETS83902.1 - 0.072 12.4 1.8 3.8 6.8 0.0 2.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 V_ATPase_I PF01496.14 ETS83902.1 - 0.19 9.5 2.5 0.23 9.2 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2528 PF10800.3 ETS83903.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Tyrosinase PF00264.15 ETS83904.1 - 1.3e-37 130.1 0.6 1.8e-37 129.6 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.13 ETS83905.1 - 1.8e-21 76.2 0.7 3.3e-21 75.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS83905.1 - 5.5e-09 35.8 13.7 0.0002 21.4 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS83905.1 - 1.3e-06 28.3 7.0 1.3e-06 28.3 4.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS83905.1 - 0.00024 21.2 14.4 0.048 14.0 2.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 ETS83905.1 - 0.13 12.3 3.9 0.41 10.8 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS83905.1 - 0.75 9.7 8.2 2.7 8.0 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 ETS83905.1 - 1.7 8.9 6.1 0.23 11.7 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2422 PF10337.4 ETS83906.1 - 6.5e-84 282.3 0.3 2.1e-83 280.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 ETS83906.1 - 5.5e-15 55.4 16.4 5.5e-15 55.4 11.3 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 ETS83906.1 - 1.5e-08 34.5 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 ETS83906.1 - 1.3e-05 24.0 2.1 2.7e-05 23.0 1.5 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter zf-C2H2_jaz PF12171.3 ETS83907.1 - 1.8e-06 27.9 7.0 0.038 14.1 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS83907.1 - 2.3e-06 27.5 9.0 0.0011 19.0 0.2 3.3 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 ETS83907.1 - 3e-06 27.2 27.8 0.00054 20.1 1.8 5.3 5 0 0 5 5 4 2 Zinc finger, C2H2 type NACHT PF05729.7 ETS83907.1 - 9.4e-06 25.3 0.0 3.1e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain zf-C2H2_4 PF13894.1 ETS83907.1 - 0.00016 21.7 27.3 0.01 16.0 1.7 6.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS83907.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 6.7 6 0 0 6 6 6 2 Zinc-finger double domain AAA_18 PF13238.1 ETS83907.1 - 0.0047 17.2 1.7 0.028 14.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS83907.1 - 0.0056 16.8 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain zf-C2H2_6 PF13912.1 ETS83907.1 - 0.0058 16.4 12.8 0.02 14.7 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger MobB PF03205.9 ETS83907.1 - 0.035 13.7 0.0 0.46 10.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 ETS83907.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS83907.1 - 0.069 13.1 0.1 0.33 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 ETS83907.1 - 0.073 13.8 1.6 0.3 11.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 ETS83907.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.14 ETS83907.1 - 0.14 11.6 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain C1_4 PF07975.7 ETS83907.1 - 0.15 12.0 5.8 0.82 9.7 1.4 3.4 2 1 1 3 3 3 0 TFIIH C1-like domain SNF2_N PF00176.18 ETS83908.1 - 1e-67 228.0 0.4 1.4e-67 227.5 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83908.1 - 3.4e-12 46.0 0.0 8.8e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 ETS83908.1 - 5.4e-05 22.8 5.4 0.00013 21.6 3.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 ETS83908.1 - 0.002 17.7 4.7 0.0062 16.1 3.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS83908.1 - 0.0027 17.3 5.2 0.0071 15.9 3.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS83908.1 - 0.0042 17.0 1.9 0.0042 17.0 1.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 ETS83908.1 - 0.0076 15.0 0.1 0.035 12.8 0.1 1.9 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.1 ETS83908.1 - 0.013 15.2 5.4 0.013 15.2 3.8 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 ETS83908.1 - 0.035 13.9 3.7 0.085 12.7 2.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 ETS83908.1 - 0.071 12.9 0.3 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 ETS83908.1 - 0.085 12.5 0.7 0.29 10.8 0.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 ETS83908.1 - 0.19 11.2 2.2 0.49 9.9 1.5 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 ETS83908.1 - 0.48 10.0 5.2 0.23 11.0 1.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PAN_4 PF14295.1 ETS83909.1 - 1.1e-06 28.1 0.6 3.6e-06 26.5 0.4 1.9 1 0 0 1 1 1 1 PAN domain MANEC PF07502.9 ETS83909.1 - 0.033 14.1 0.1 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 MANEC domain ADH_N PF08240.7 ETS83910.1 - 4.1e-30 103.7 0.2 8.2e-30 102.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83910.1 - 1.2e-23 83.0 0.4 1.8e-23 82.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS83910.1 - 0.00029 21.7 0.2 0.0006 20.7 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1967 PF09269.6 ETS83910.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) ABC_membrane PF00664.18 ETS83911.1 - 4.7e-81 272.2 25.1 1.1e-47 162.7 3.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS83911.1 - 6.4e-67 224.0 0.0 2.7e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS83911.1 - 4.6e-16 58.7 0.0 2e-05 23.9 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS83911.1 - 1.9e-09 37.8 0.1 0.027 14.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 ETS83911.1 - 5.8e-09 35.3 0.1 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS83911.1 - 1.1e-07 32.7 0.0 0.005 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS83911.1 - 3.9e-07 30.2 0.0 0.41 10.8 0.0 4.9 5 0 0 5 5 5 2 AAA domain DUF258 PF03193.11 ETS83911.1 - 2.9e-06 26.5 0.0 0.0047 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 ETS83911.1 - 6.6e-06 26.2 5.9 0.011 15.6 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 ETS83911.1 - 1.1e-05 24.9 0.3 0.15 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 ETS83911.1 - 2.6e-05 24.0 2.5 0.18 11.7 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 ETS83911.1 - 3.2e-05 23.6 0.1 0.009 15.6 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.1 ETS83911.1 - 4e-05 23.2 0.0 0.23 11.0 0.0 4.1 5 0 0 5 5 4 1 AAA domain ABC_ATPase PF09818.4 ETS83911.1 - 4e-05 22.3 1.7 0.0013 17.4 0.0 3.2 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 ETS83911.1 - 0.00015 21.6 0.3 0.36 10.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 ETS83911.1 - 0.00027 21.2 0.0 0.37 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 ETS83911.1 - 0.00033 19.8 0.1 0.72 8.9 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 ETS83911.1 - 0.00037 20.8 0.0 0.099 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 ETS83911.1 - 0.0022 17.9 0.2 3.5 7.6 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS83911.1 - 0.0024 17.3 1.1 0.73 9.2 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 ETS83911.1 - 0.0027 17.5 0.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 ETS83911.1 - 0.005 16.5 0.1 5.3 6.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS83911.1 - 0.0073 16.2 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 ETS83911.1 - 0.012 15.2 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 ETS83911.1 - 0.066 12.7 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 ETS83911.1 - 0.12 12.6 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 ETS83911.1 - 0.42 9.2 0.0 3.4 6.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit MFS_1 PF07690.11 ETS83912.1 - 6.9e-28 97.3 47.6 1.8e-25 89.4 32.1 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.23 ETS83913.1 - 7.3e-99 330.9 0.0 9.8e-99 330.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS83913.1 - 6.8e-11 42.9 0.0 1.6e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.6 ETS83914.1 - 2.3e-23 82.9 0.0 1.1e-20 74.2 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Picorna_P3A PF06363.6 ETS83915.1 - 0.043 13.8 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Picornaviridae P3A protein TMEM107 PF14995.1 ETS83915.1 - 0.16 12.1 0.5 0.17 11.9 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 ETS83916.1 - 1.3e-32 112.9 24.8 2.9e-30 105.1 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83916.1 - 1.7e-14 53.2 0.2 1.7e-14 53.2 0.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS83916.1 - 0.00022 19.7 22.1 0.017 13.5 5.1 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_3 PF05977.8 ETS83916.1 - 0.0044 15.2 11.0 0.025 12.7 1.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector PAN_4 PF14295.1 ETS83917.1 - 4.3e-07 29.5 3.8 8e-07 28.6 2.7 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 ETS83917.1 - 0.055 13.2 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 PAN domain DUF1469 PF07332.6 ETS83917.1 - 0.066 12.9 0.8 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF515 PF04415.7 ETS83917.1 - 9.5 4.3 8.4 14 3.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pyr_redox PF00070.22 ETS83918.1 - 6.9e-10 39.1 0.0 1.5e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS83918.1 - 7.6e-10 39.0 0.4 0.00014 21.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS83918.1 - 1.9e-06 28.1 0.4 0.22 11.5 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS83918.1 - 0.00078 18.4 0.2 0.013 14.4 0.1 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 ETS83918.1 - 0.00088 19.0 1.2 11 5.7 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 ETS83918.1 - 0.0034 16.3 0.7 0.49 9.2 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS83918.1 - 0.012 14.5 0.1 0.35 9.7 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS83918.1 - 0.018 13.7 0.1 0.91 8.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 ETS83918.1 - 0.019 15.1 0.3 0.056 13.6 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 ETS83918.1 - 0.022 13.2 1.6 5.4 5.3 0.3 3.0 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 ETS83918.1 - 0.026 13.5 0.0 2.1 7.3 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.1 ETS83918.1 - 0.045 13.7 0.3 4 7.5 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GCHY-1 PF02649.9 ETS83918.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Acetyltransf_8 PF13523.1 ETS83919.1 - 3.1e-38 131.0 0.5 4.5e-38 130.5 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS83919.1 - 0.0068 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1688 PF07958.6 ETS83920.1 - 2.5e-160 533.5 0.0 2.9e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Apolipoprotein PF01442.13 ETS83921.1 - 0.00052 19.5 11.0 0.052 13.0 5.6 3.3 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Glyco_hydro_3_C PF01915.17 ETS83921.1 - 0.00074 19.1 0.1 0.00074 19.1 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Globin PF00042.17 ETS83921.1 - 0.002 18.4 1.6 0.56 10.5 0.0 3.7 1 1 2 3 3 3 1 Globin Glyco_hydro_57 PF03065.10 ETS83921.1 - 0.0032 16.4 0.0 0.0064 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Phasin_2 PF09361.5 ETS83921.1 - 0.025 14.6 15.2 2.9 7.9 0.1 5.6 5 1 0 5 5 5 0 Phasin protein Hemerythrin PF01814.18 ETS83921.1 - 0.15 12.2 0.8 22 5.2 0.1 3.4 2 1 0 3 3 3 0 Hemerythrin HHE cation binding domain ATP-synt_B PF00430.13 ETS83921.1 - 0.19 11.5 20.6 2.3 8.0 3.2 4.3 4 0 0 4 4 4 0 ATP synthase B/B' CF(0) DUF1771 PF08590.5 ETS83921.1 - 0.68 9.9 14.9 0.26 11.3 0.3 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) Peptidase_M41 PF01434.13 ETS83921.1 - 1.1 8.6 11.3 0.78 9.1 2.9 3.3 2 2 1 4 4 4 0 Peptidase family M41 Senescence PF06911.7 ETS83921.1 - 2.8 7.6 9.6 0.78 9.4 1.8 3.2 2 2 0 2 2 2 0 Senescence-associated protein TMP_2 PF06791.8 ETS83921.1 - 3.8 7.0 12.3 1 8.9 0.3 4.2 4 3 1 5 5 5 0 Prophage tail length tape measure protein DUF883 PF05957.8 ETS83921.1 - 5.4 7.4 18.5 38 4.7 0.0 5.6 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 ETS83921.1 - 9.9 3.5 7.0 12 3.3 0.0 2.7 1 1 1 3 3 3 0 Prominin Transp_cyt_pur PF02133.10 ETS83922.1 - 2.4e-89 299.9 38.5 2.8e-89 299.7 26.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1399 PF07173.7 ETS83923.1 - 5.6e-24 84.9 0.1 3.2e-16 59.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) GTP_EFTU PF00009.22 ETS83924.1 - 2.8e-21 75.8 0.0 4.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS83924.1 - 1.5e-15 57.1 0.3 3.4e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS83924.1 - 2.2e-11 43.6 0.3 1.5e-10 41.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 ETS83924.1 - 0.0014 18.0 0.4 0.48 9.9 0.1 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 ETS83924.1 - 0.0025 18.2 0.0 0.014 15.9 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS83924.1 - 0.0035 17.2 0.1 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 ETS83924.1 - 0.015 14.9 0.9 0.039 13.6 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 ETS83924.1 - 0.06 13.1 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Dynamin family p450 PF00067.17 ETS83925.1 - 9.7e-73 245.2 0.0 1.1e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 ETS83926.1 - 7.6e-24 84.8 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS83926.1 - 3e-15 56.2 0.0 1e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 ETS83926.1 - 2.8e-09 36.6 0.3 2.1e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 ETS83926.1 - 1.6e-08 34.4 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 ETS83926.1 - 2.6e-05 23.9 0.1 7.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 ETS83926.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.1 ETS83926.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF2305 PF10230.4 ETS83926.1 - 0.0038 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 ETS83926.1 - 0.0049 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Y_phosphatase PF00102.22 ETS83926.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 ETS83926.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Tyrosine phosphatase family VirJ PF06057.6 ETS83926.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF900 PF05990.7 ETS83926.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 ETS83926.1 - 0.13 11.1 0.5 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 ETS83926.1 - 0.15 11.5 0.5 2.9 7.2 0.3 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 ETS83926.1 - 0.2 9.9 0.1 0.76 8.0 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF498 PF04430.9 ETS83927.1 - 1e-25 89.4 0.0 1.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.13 ETS83928.1 - 1.2e-35 121.5 2.1 1.5e-35 121.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.1 ETS83928.1 - 0.084 13.1 0.3 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 ETS83928.1 - 0.22 10.7 2.1 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain FhuF_C PF11575.3 ETS83928.1 - 0.68 9.6 6.4 2.5 7.8 0.2 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.6 ETS83929.1 - 8.7e-223 739.1 6.5 1.4e-222 738.4 4.5 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 ETS83929.1 - 3.4e-125 415.9 1.0 6.9e-125 414.9 0.7 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 ETS83929.1 - 2.4e-94 313.0 1.1 6e-94 311.7 0.7 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 ETS83929.1 - 5e-77 256.7 2.2 5e-77 256.7 1.5 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 ETS83929.1 - 2.2e-67 224.8 0.2 4.7e-67 223.7 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 ETS83929.1 - 1.1e-43 147.0 0.2 2.7e-43 145.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 ETS83929.1 - 5.4e-42 142.4 0.0 1.7e-41 140.8 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF3753 PF12575.3 ETS83929.1 - 0.097 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 ETS83929.1 - 0.22 10.2 0.4 0.38 9.4 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ank_2 PF12796.2 ETS83930.1 - 2.9e-49 165.3 1.8 1.7e-15 57.1 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS83930.1 - 6.9e-38 126.6 3.7 2.7e-07 30.0 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETS83930.1 - 1.9e-32 110.5 4.5 1.1e-08 34.9 0.1 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS83930.1 - 2.1e-27 94.9 11.2 9.2e-08 32.4 0.0 5.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS83930.1 - 2.3e-27 92.3 0.5 2.8e-06 27.0 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat HEAT PF02985.17 ETS83930.1 - 0.095 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat MNE1 PF13762.1 ETS83930.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component zf-RING_3 PF14369.1 ETS83931.1 - 0.032 14.2 0.8 0.098 12.6 0.5 1.8 1 0 0 1 1 1 0 zinc-finger zinc_ribbon_5 PF13719.1 ETS83931.1 - 0.13 11.8 0.3 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS83931.1 - 0.13 11.9 0.4 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Myb_DNA-bind_6 PF13921.1 ETS83932.1 - 9.4e-15 54.4 0.2 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS83932.1 - 5.4e-13 48.7 0.2 3.4e-05 23.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4587 PF15248.1 ETS83932.1 - 0.072 13.6 2.5 2.1 8.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) ApbA_C PF08546.6 ETS83933.1 - 1.2e-25 89.8 0.0 4.4e-25 88.0 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS83933.1 - 1.7e-22 79.5 0.0 3.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF334 PF03904.8 ETS83933.1 - 0.059 12.6 0.3 0.09 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Mpv17_PMP22 PF04117.7 ETS83934.1 - 4.8e-11 42.1 1.8 5.5e-10 38.7 1.0 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF935 PF06074.7 ETS83935.1 - 0.094 11.4 0.1 0.094 11.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Lipase_GDSL_2 PF13472.1 ETS83936.1 - 3.1e-05 24.1 0.0 3.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MaoC_dehydrat_N PF13452.1 ETS83937.1 - 0.013 15.2 0.0 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase PD40 PF07676.7 ETS83938.1 - 0.59 9.8 7.6 3.1 7.5 0.1 4.2 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat Fungal_trans PF04082.13 ETS83939.1 - 8.3e-16 57.6 0.0 1.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.12 ETS83941.1 - 1.2e-113 378.9 0.8 1.8e-113 378.4 0.6 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS83941.1 - 3.5e-43 147.3 1.2 6e-43 146.5 0.8 1.4 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.15 ETS83942.1 - 6.6e-85 284.6 0.0 7.4e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short_C2 PF13561.1 ETS83943.1 - 1.2e-28 100.4 0.5 1.5e-28 100.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS83943.1 - 2e-23 83.1 0.4 2.9e-23 82.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS83943.1 - 3.8e-06 26.6 0.1 5.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 ETS83943.1 - 0.077 13.0 0.3 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain Coat_X PF07552.6 ETS83943.1 - 0.12 12.1 0.3 0.3 10.8 0.2 1.7 1 0 0 1 1 1 0 Spore Coat Protein X and V domain MFS_1 PF07690.11 ETS83944.1 - 1.3e-41 142.5 51.9 1.5e-35 122.5 21.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 ETS83944.1 - 0.72 9.9 0.0 0.72 9.9 0.0 4.2 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding NAD_binding_10 PF13460.1 ETS83945.1 - 0.00046 20.2 0.0 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Glycos_transf_N PF04413.11 ETS83945.1 - 0.0058 15.8 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) PQQ_3 PF13570.1 ETS83946.1 - 0.047 13.9 4.1 37 4.7 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain FAD_binding_4 PF01565.18 ETS83949.1 - 1.2e-23 83.1 1.7 2.1e-23 82.3 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS83949.1 - 0.011 15.6 0.1 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Neil1-DNA_bind PF09292.5 ETS83949.1 - 0.02 14.7 0.1 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Fungal_trans PF04082.13 ETS83950.1 - 4.7e-34 117.4 0.6 7.6e-34 116.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83950.1 - 2.2e-08 33.8 13.9 4.8e-08 32.7 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 ETS83951.1 - 1.8e-30 105.9 0.0 7.5e-30 103.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 ETS83951.1 - 0.0043 16.0 0.0 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 ETS83951.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AA_permease PF00324.16 ETS83952.1 - 7.3e-113 377.4 46.2 8.7e-113 377.1 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS83952.1 - 2e-29 102.4 47.9 2.5e-29 102.1 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_8 PF13450.1 ETS83953.1 - 7.6e-10 38.6 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS83953.1 - 1.5e-06 28.3 0.1 4.8e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS83953.1 - 1.6e-06 27.4 0.0 2.9e-06 26.6 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 ETS83953.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS83953.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 ETS83953.1 - 0.025 13.4 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS83953.1 - 0.03 14.0 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 ETS83953.1 - 0.031 13.3 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 ETS83953.1 - 0.044 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 ETS83953.1 - 0.046 12.1 0.0 0.083 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Reg_prop PF07494.6 ETS83954.1 - 0.00046 19.8 0.2 0.0031 17.3 0.1 2.4 2 0 0 2 2 2 1 Two component regulator propeller p450 PF00067.17 ETS83955.1 - 1.7e-63 214.7 0.0 2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS83956.1 - 2.6e-23 82.7 0.0 5.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 ETS83957.1 - 1.2e-08 34.7 6.2 2.2e-08 33.8 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3237 PF11578.3 ETS83958.1 - 1.7e-06 27.3 0.1 2.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Glyco_hydro_16 PF00722.16 ETS83959.1 - 3.2e-13 49.3 0.7 5.1e-13 48.7 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NmrA PF05368.8 ETS83960.1 - 1.9e-23 82.9 0.0 2.6e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF3352 PF11832.3 ETS83960.1 - 0.11 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) Tannase PF07519.6 ETS83961.1 - 1.8e-113 379.7 0.1 2.2e-113 379.4 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase p450 PF00067.17 ETS83962.1 - 2.8e-66 223.9 0.0 3.3e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL PF07366.7 ETS83963.1 - 0.00013 21.4 0.0 0.00017 21.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 ETS83963.1 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain HET PF06985.6 ETS83964.1 - 0.033 14.3 0.1 0.07 13.2 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Asp PF00026.18 ETS83965.1 - 8.9e-76 255.1 16.3 1.1e-75 254.9 11.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS83965.1 - 9.9e-09 35.3 2.1 1e-07 32.0 0.5 2.8 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS83965.1 - 7.1e-05 23.2 1.7 0.43 11.1 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease Peptidase_M28 PF04389.12 ETS83966.1 - 1.4e-33 116.1 0.0 2e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS83966.1 - 2.7e-15 55.8 0.2 5.7e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 ETS83966.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 ETS83966.1 - 0.12 11.1 0.0 0.24 10.1 0.0 1.6 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase SnoaL_2 PF12680.2 ETS83967.1 - 1.6e-05 25.2 0.1 3.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 ETS83967.1 - 0.00039 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Fungal_trans PF04082.13 ETS83968.1 - 9.9e-35 119.6 0.1 1.4e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS83968.1 - 0.00028 20.7 2.2 0.00028 20.7 1.5 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 ETS83968.1 - 0.025 14.4 1.1 0.069 13.0 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HpcH_HpaI PF03328.9 ETS83969.1 - 6.7e-41 139.5 0.1 8.8e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 ETS83969.1 - 0.00051 19.3 0.4 0.02 14.1 0.0 2.7 2 1 1 3 3 3 2 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 ETS83970.1 - 6.3e-38 130.3 41.4 2.4e-35 121.9 16.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS83970.1 - 1.3e-13 50.4 16.5 1.8e-13 49.9 11.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter RseC_MucC PF04246.7 ETS83970.1 - 0.023 14.2 8.4 0.22 11.1 0.6 3.8 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF948 PF06103.6 ETS83970.1 - 0.096 12.5 0.4 25 4.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Wzz PF02706.10 ETS83970.1 - 2 8.2 5.4 6.6 6.5 0.3 3.3 3 0 0 3 3 3 0 Chain length determinant protein ADH_N PF08240.7 ETS83971.1 - 2.7e-28 97.8 2.6 2.7e-28 97.8 1.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS83971.1 - 2.3e-19 69.2 0.1 3.6e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS83971.1 - 0.00014 22.7 0.0 0.00027 21.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PIN PF01850.16 ETS83971.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 PIN domain 2-Hacid_dh_C PF02826.14 ETS83971.1 - 0.071 12.2 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS83971.1 - 0.11 11.8 0.1 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldo_ket_red PF00248.16 ETS83972.1 - 7.8e-45 152.8 0.0 8.7e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.18 ETS83973.1 - 2.6e-67 226.7 0.0 3.6e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 ETS83973.1 - 1.6e-51 174.9 1.1 8.4e-51 172.5 0.6 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 ETS83973.1 - 6.2e-13 48.4 0.0 2.2e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETS83973.1 - 3e-05 23.0 0.0 8.8e-05 21.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 ETS83973.1 - 0.003 17.4 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 ETS83973.1 - 0.13 12.4 0.0 1.6 8.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 ETS83974.1 - 3.4e-49 164.4 2.5 2.6e-17 62.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_2 PF02230.11 ETS83975.1 - 3.8e-27 95.1 0.0 8.4e-17 61.3 0.0 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETS83975.1 - 2.5e-06 27.2 0.0 3.9e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 ETS83975.1 - 5.6e-06 25.9 0.0 3.8e-05 23.2 0.0 2.1 2 1 0 3 3 3 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 ETS83975.1 - 1e-05 25.5 0.1 0.00027 20.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS83975.1 - 0.053 12.9 0.0 1.2 8.4 0.0 2.4 3 0 0 3 3 3 0 Putative esterase Abhydrolase_3 PF07859.8 ETS83975.1 - 0.094 12.2 0.0 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Acyl-CoA_dh_1 PF00441.19 ETS83977.1 - 1.9e-24 86.5 0.2 2.9e-24 85.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS83977.1 - 1.4e-21 77.1 0.2 3.1e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS83977.1 - 2.2e-16 59.1 0.0 5.3e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 ETS83977.1 - 1.2e-07 32.0 0.1 2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2000 PF09391.5 ETS83978.1 - 0.0051 16.4 0.2 0.047 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2000) CorA PF01544.13 ETS83978.1 - 0.037 13.0 7.9 0.12 11.3 5.4 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 ETS83979.1 - 5.2e-20 71.6 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS83979.1 - 2.2e-13 49.9 0.0 4.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sec34 PF04136.10 ETS83980.1 - 1.4e-30 106.0 0.3 4.1e-30 104.5 0.2 1.8 1 0 0 1 1 1 1 Sec34-like family Med11 PF10280.4 ETS83980.1 - 0.12 12.4 2.4 17 5.4 0.0 3.1 2 0 0 2 2 2 0 Mediator complex protein RCC1 PF00415.13 ETS83981.1 - 4.1e-27 94.1 5.1 1.2e-05 25.3 0.0 7.3 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS83981.1 - 2.6e-16 58.7 15.4 3.3e-10 39.3 0.0 6.4 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat FRQ PF09421.5 ETS83982.1 - 6e-284 944.5 55.3 7.4e-284 944.2 38.3 1.0 1 0 0 1 1 1 1 Frequency clock protein PTS_2-RNA PF01885.11 ETS83982.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Ada3 PF10198.4 ETS83983.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Erp_C PF06780.6 ETS83984.1 - 0.073 12.9 1.0 0.44 10.3 0.1 2.4 2 1 0 2 2 2 0 Erp protein C-terminus Mito_carr PF00153.22 ETS83985.1 - 7e-66 217.9 2.9 1.4e-21 75.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 ETS83986.1 - 2.4e-92 310.0 0.0 3.7e-92 309.4 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.1 ETS83986.1 - 0.0013 18.7 12.5 0.0018 18.3 3.4 3.9 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) CRISPR_Cse2 PF09485.5 ETS83986.1 - 0.029 14.3 2.0 0.17 11.9 1.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) CcdB PF01845.12 ETS83986.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 CcdB protein SseC PF04888.7 ETS83986.1 - 0.49 9.6 1.0 1 8.6 0.7 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TPR_MLP1_2 PF07926.7 ETS83986.1 - 0.99 9.1 7.2 0.49 10.1 0.9 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 ETS83986.1 - 2.2 7.9 8.7 0.22 11.2 1.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 ETS83986.1 - 2.8 7.5 16.6 2.5 7.6 9.6 2.4 2 1 0 2 2 2 0 IncA protein DnaJ PF00226.26 ETS83987.1 - 1.9e-12 46.7 1.3 1.9e-12 46.7 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain DUF4358 PF14270.1 ETS83987.1 - 0.1 12.4 1.5 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Glyco_hydro_18 PF00704.23 ETS83988.1 - 2.4e-09 37.1 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SNF2_N PF00176.18 ETS83989.1 - 7.4e-70 235.1 0.0 1.2e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS83989.1 - 5.1e-16 58.2 0.0 1.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 ETS83989.1 - 0.00017 20.5 0.0 0.0032 16.3 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Ribosomal_S11 PF00411.14 ETS83990.1 - 1.9e-40 137.4 0.6 2.3e-40 137.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 ETS83990.1 - 0.078 11.8 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_L30_N PF08079.7 ETS83991.1 - 5.7e-24 83.9 20.6 9.3e-24 83.2 14.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 ETS83991.1 - 2e-20 72.1 1.4 2e-20 72.1 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EthD PF07110.6 ETS83992.1 - 0.00011 23.1 0.3 0.00018 22.3 0.2 1.4 1 1 0 1 1 1 1 EthD domain DUF1330 PF07045.6 ETS83992.1 - 0.079 12.8 0.4 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) DUF3237 PF11578.3 ETS83993.1 - 1.5e-14 53.5 0.0 1.7e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.11 ETS83994.1 - 1.2e-32 113.0 26.5 1.2e-32 113.0 18.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PIP5K PF01504.13 ETS83995.1 - 1.8e-86 289.3 0.0 3e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.12 ETS83996.1 - 7.1e-22 77.2 4.6 9.4e-22 76.8 3.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 ETS83996.1 - 0.0024 17.9 0.2 0.0037 17.3 0.2 1.3 1 0 0 1 1 1 1 Prolamin-like Pet191_N PF10203.4 ETS83996.1 - 0.0057 16.6 0.4 0.011 15.8 0.3 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NP1-WLL PF11733.3 ETS83996.1 - 0.039 14.2 0.6 0.12 12.6 0.2 1.8 2 0 0 2 2 2 0 Non-capsid protein NP1 Tox-HNH-HHH PF15637.1 ETS83996.1 - 0.07 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Ndufs5 PF10200.4 ETS83996.1 - 0.82 9.6 3.9 1.7 8.6 2.6 1.7 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa SYS1 PF09801.4 ETS83997.1 - 8.9e-47 158.7 3.0 1e-46 158.5 2.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Herpes_UL43 PF05072.8 ETS83997.1 - 0.2 10.3 6.8 0.26 9.9 4.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Cu_amine_oxid PF01179.15 ETS83998.1 - 2.2e-113 379.1 2.6 2.7e-113 378.8 1.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 ETS83998.1 - 6.5e-34 115.6 0.5 1.5e-33 114.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 ETS83998.1 - 9.7e-06 25.5 0.1 2.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Aminotran_1_2 PF00155.16 ETS83999.1 - 2.4e-60 204.4 0.0 3.4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS83999.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 ETS83999.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.23 ETS84000.1 - 8.7e-53 179.2 0.0 1.1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84000.1 - 4.4e-07 30.7 0.0 9.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ran_BP1 PF00638.13 ETS84001.1 - 7.8e-49 164.7 1.2 1.3e-48 164.0 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 ETS84001.1 - 0.0064 16.2 0.2 0.03 14.0 0.1 1.9 1 1 0 1 1 1 1 WH1 domain PS-DH PF14765.1 ETS84001.1 - 0.0076 15.4 0.1 0.017 14.2 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF1681 PF07933.9 ETS84001.1 - 0.037 13.6 0.2 0.084 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) Phosducin PF02114.11 ETS84003.1 - 3.9e-12 45.4 3.1 2.3e-11 42.9 0.2 2.6 2 1 0 2 2 2 1 Phosducin DUF3657 PF12394.3 ETS84003.1 - 0.042 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3657) WD40 PF00400.27 ETS84004.1 - 3.9e-48 159.6 21.0 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 ETS84004.1 - 0.00015 21.5 0.0 0.079 12.6 0.0 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A A_deaminase PF00962.17 ETS84005.1 - 1.4e-28 99.7 0.0 1.9e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 ETS84005.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family DUF4211 PF13926.1 ETS84006.1 - 8.8e-42 142.1 0.4 1.3e-40 138.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) WD40 PF00400.27 ETS84007.1 - 6e-21 73.4 7.4 1.7e-07 30.8 0.1 5.5 6 1 0 6 6 6 4 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 ETS84008.1 - 4.6e-15 56.2 0.0 1.1e-13 51.7 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS84008.1 - 0.077 12.8 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Acetyltransf_1 PF00583.19 ETS84009.1 - 1.3e-10 41.1 0.1 3.4e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS84009.1 - 7.1e-08 32.5 0.1 1.6e-07 31.3 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS84009.1 - 8.6e-06 25.6 0.2 2.9e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS84009.1 - 8.7e-05 22.2 0.1 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS84009.1 - 0.00025 21.1 0.0 0.00084 19.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS84009.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.1 ETS84009.1 - 0.0074 16.8 0.0 3.1 8.4 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain HATPase_c_4 PF13749.1 ETS84009.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal RasGEF PF00617.14 ETS84011.1 - 2.2e-63 213.3 0.1 4.2e-63 212.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 ETS84011.1 - 2.3e-26 91.9 0.6 5.1e-26 90.7 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 ETS84011.1 - 5.9e-16 57.5 0.1 1.4e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 ETS84011.1 - 3.2e-14 52.2 0.9 6.3e-14 51.2 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 ETS84011.1 - 1.9e-13 49.6 0.1 4.8e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 ETS84011.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 WW domain Drf_FH1 PF06346.7 ETS84011.1 - 0.1 12.1 0.4 0.23 10.9 0.3 1.5 1 0 0 1 1 1 0 Formin Homology Region 1 Fungal_trans PF04082.13 ETS84012.1 - 3.3e-16 58.9 1.7 5.5e-16 58.2 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 ETS84012.1 - 4.9e-08 32.8 12.3 1.6e-05 24.9 4.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS84012.1 - 0.00013 22.0 12.4 0.008 16.4 3.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS84012.1 - 0.0012 19.0 13.7 0.2 12.0 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 ETS84013.1 - 2.1e-16 59.7 0.1 4e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Stm1_N PF09598.5 ETS84014.1 - 0.6 10.8 3.6 1.2 9.9 2.5 1.4 1 0 0 1 1 1 0 Stm1 Sas10 PF09368.5 ETS84015.1 - 1.9e-28 98.4 10.8 1.9e-28 98.4 7.5 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 ETS84015.1 - 1.7e-13 50.5 5.3 2.4e-12 46.8 0.0 3.5 3 0 0 3 3 3 2 Sas10/Utp3/C1D family NRDE-2 PF08424.5 ETS84016.1 - 6.1e-77 258.6 0.8 6.1e-77 258.6 0.6 2.9 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 ETS84016.1 - 0.0049 17.5 0.1 2.1 9.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS84016.1 - 0.27 11.5 1.6 7.4 6.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Voltage_CLC PF00654.15 ETS84017.1 - 1.1e-90 304.2 22.4 1.1e-90 304.2 15.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel FUSC PF04632.7 ETS84017.1 - 0.29 9.5 5.2 0.67 8.3 3.6 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family TAT_signal PF10518.4 ETS84017.1 - 1.4 9.1 11.0 0.074 13.0 2.1 3.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PIG-L PF02585.12 ETS84019.1 - 2.3e-28 99.2 0.0 3.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cytochrom_B_N_2 PF13631.1 ETS84019.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1242 PF06842.7 ETS84019.1 - 0.22 11.0 1.4 0.5 9.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) ATP13 PF12921.2 ETS84020.1 - 1.6e-16 59.8 0.0 4.7e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.1 ETS84020.1 - 1.9e-05 24.5 0.2 0.28 11.5 0.0 3.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain LSM PF01423.17 ETS84021.1 - 1.1e-13 50.4 1.2 2.4e-13 49.4 0.8 1.5 1 1 0 1 1 1 1 LSM domain Phage_portal PF04860.7 ETS84021.1 - 0.12 11.0 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Phage portal protein MFS_1 PF07690.11 ETS84022.1 - 9.4e-40 136.3 20.7 4e-39 134.3 14.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CD34_antigen PF06365.7 ETS84022.1 - 0.03 13.9 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4231 PF14015.1 ETS84022.1 - 0.088 12.8 8.8 4.1 7.4 0.2 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) ESSS PF10183.4 ETS84022.1 - 0.16 12.4 0.1 0.6 10.5 0.1 2.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1049 PF06305.6 ETS84022.1 - 0.7 9.4 9.8 6.4 6.3 0.1 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1049) EXS PF03124.9 ETS84022.1 - 1.7 7.6 7.7 1.2 8.1 3.1 2.3 2 1 0 2 2 2 0 EXS family DUF3112 PF11309.3 ETS84022.1 - 2.1 8.1 10.7 0.72 9.6 0.3 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3112) Bromodomain PF00439.20 ETS84023.1 - 2.5e-34 117.0 1.3 1.8e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 ETS84023.1 - 9.6e-14 51.1 0.8 1.9e-13 50.1 0.5 1.5 1 0 0 1 1 1 1 BAH domain DUF2312 PF10073.4 ETS84024.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) CagE_TrbE_VirB PF03135.9 ETS84026.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Glyco_hydro_17 PF00332.13 ETS84027.1 - 1.3e-05 24.4 0.5 0.00028 20.0 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 ETS84028.1 - 4.7e-37 127.7 0.0 5.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 ETS84028.1 - 0.036 12.3 0.0 0.061 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.10 ETS84029.1 - 0 1455.0 0.0 0 1454.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 ETS84029.1 - 5.1e-39 132.7 0.4 1.2e-38 131.6 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.4 ETS84030.1 - 1.8e-40 138.2 5.8 1.8e-40 138.2 4.0 1.9 2 0 0 2 2 2 1 SprT-like family Mog1 PF04603.7 ETS84031.1 - 8e-15 55.0 0.0 3.7e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Rsa3 PF14615.1 ETS84032.1 - 1.3e-20 72.3 1.0 1.7e-20 71.9 0.7 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 UCH PF00443.24 ETS84033.1 - 2e-53 181.2 3.4 2.8e-53 180.7 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS84033.1 - 8.4e-33 114.0 1.7 1.1e-32 113.6 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS84033.1 - 6.5e-07 29.3 0.6 6.5e-07 29.3 0.4 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Lactamase_B PF00753.22 ETS84034.1 - 2e-23 83.0 1.4 2.9e-23 82.5 1.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS84034.1 - 0.00019 21.0 0.3 0.00032 20.3 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NACHT PF05729.7 ETS84034.1 - 0.0045 16.6 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 NACHT domain Lactamase_B_3 PF13483.1 ETS84034.1 - 0.029 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HemN_C PF06969.11 ETS84034.1 - 0.1 12.6 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 HemN C-terminal domain NifT PF06988.6 ETS84034.1 - 0.15 11.5 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NifT/FixU protein Ytp1 PF10355.4 ETS84035.1 - 4.5e-105 350.7 7.7 7.2e-105 350.0 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 ETS84035.1 - 2.5e-34 116.9 4.1 2.5e-34 116.9 2.9 3.9 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) NAD_binding_10 PF13460.1 ETS84036.1 - 6.4e-21 75.1 0.0 9.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS84036.1 - 9.9e-17 60.9 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 ETS84036.1 - 2e-14 53.6 0.1 4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS84036.1 - 1.4e-11 43.6 0.0 4.9e-11 41.8 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS84036.1 - 1.5e-08 33.9 0.0 1.6e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 ETS84036.1 - 1.4e-05 24.1 0.2 0.0037 16.2 0.1 3.1 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 ETS84036.1 - 0.00046 20.1 0.0 0.00092 19.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 ETS84036.1 - 0.003 16.5 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 ETS84036.1 - 0.015 14.9 0.0 0.18 11.4 0.0 2.1 1 1 0 1 1 1 0 KR domain DDE_Tnp_1_3 PF13612.1 ETS84036.1 - 0.081 12.6 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain ApbA PF02558.11 ETS84036.1 - 0.097 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 ETS84036.1 - 0.14 11.0 0.0 0.38 9.6 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.22 ETS84037.1 - 4.5e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain tRNA-synt_1c PF00749.16 ETS84037.1 - 0.033 12.8 0.1 0.056 12.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Gaa1 PF04114.9 ETS84038.1 - 1.4e-100 337.3 0.8 1.8e-100 337.0 0.6 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 ETS84039.1 - 1.3e-12 47.9 10.3 1.3e-12 47.9 7.2 1.7 2 0 0 2 2 2 1 Rhomboid family Aconitase PF00330.15 ETS84040.1 - 1.6e-171 570.9 0.0 3.8e-171 569.6 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS84040.1 - 1.8e-46 157.5 0.0 3.4e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 ETS84041.1 - 1.9e-08 34.2 0.1 3.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS84041.1 - 0.013 15.7 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3279 PF11682.3 ETS84041.1 - 0.1 12.1 0.3 0.14 11.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3279) DASH_Dam1 PF08653.5 ETS84042.1 - 1.7e-27 94.9 0.9 2.3e-27 94.4 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 ETS84043.1 - 3.8e-42 143.4 0.0 6.9e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS84043.1 - 3.5e-13 49.4 0.3 1.1e-12 47.8 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 ETS84043.1 - 2.3e-11 43.8 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 ETS84044.1 - 2.6e-22 79.1 0.1 3.3e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 ETS84044.1 - 2.8e-13 50.1 0.0 3.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 ETS84044.1 - 5.3e-05 22.8 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 ETS84044.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.5 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 CFC PF09443.5 ETS84044.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Gelsolin PF00626.17 ETS84045.1 - 8.6e-33 111.8 0.1 5.9e-10 38.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat OTU PF02338.14 ETS84046.1 - 1.8e-12 47.8 0.0 3.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease FmdA_AmdA PF03069.10 ETS84047.1 - 5.6e-153 509.0 0.0 6.4e-153 508.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 ETS84048.1 - 9.5e-07 28.4 12.4 5e-05 22.8 8.6 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 ETS84049.1 - 1.3e-34 118.9 0.0 7e-34 116.5 0.0 2.3 3 0 0 3 3 3 1 Inheritance of peroxisomes protein 1 AAA_23 PF13476.1 ETS84050.1 - 0.23 11.7 9.5 0.37 11.0 6.6 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 ETS84050.1 - 0.74 9.6 6.4 0.31 10.9 3.0 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 ETS84050.1 - 1.1 9.0 15.4 2.4 7.9 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) eIF-3_zeta PF05091.7 ETS84050.1 - 8.6 4.8 14.4 15 4.0 10.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.1 ETS84050.1 - 8.8 3.8 27.3 14 3.1 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAS_9 PF13426.1 ETS84051.1 - 1.7e-34 118.2 0.0 5.2e-19 68.5 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 ETS84051.1 - 1.2e-18 67.0 0.0 5.3e-11 42.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 ETS84051.1 - 3.2e-18 65.5 0.0 6.9e-07 29.0 0.0 3.7 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 ETS84051.1 - 7.4e-15 54.0 9.8 1.3e-14 53.1 6.3 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_11 PF14598.1 ETS84051.1 - 1.6e-13 50.5 0.0 3.5e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 ETS84051.1 - 1.3e-08 34.8 0.0 0.0067 16.4 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_2 PF08446.6 ETS84051.1 - 0.00051 20.4 0.0 0.59 10.6 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 ETS84051.1 - 0.022 14.5 0.0 0.58 10.1 0.0 2.6 2 0 0 2 2 2 0 PAS domain HEAT_2 PF13646.1 ETS84052.1 - 1.1e-20 73.6 12.1 2.2e-08 34.2 0.1 8.2 5 3 5 10 10 9 5 HEAT repeats HEAT PF02985.17 ETS84052.1 - 8.7e-18 62.7 17.7 0.0084 16.1 0.0 11.2 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 ETS84052.1 - 6.8e-17 61.4 19.5 3e-07 30.7 0.2 10.1 9 1 3 12 12 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS84052.1 - 3.7e-14 52.8 0.1 0.013 15.8 0.0 8.0 6 2 3 9 9 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 ETS84052.1 - 6.2e-09 35.5 1.2 0.3 10.3 0.1 6.1 4 1 0 6 6 6 2 CLASP N terminal MMS19_C PF12460.3 ETS84052.1 - 6.2e-08 31.7 0.0 1e-05 24.4 0.1 3.3 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 ETS84052.1 - 1.1e-07 31.6 0.0 0.0011 18.6 0.0 4.8 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 ETS84052.1 - 1.6e-05 24.8 1.1 0.18 11.6 0.0 4.4 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 ETS84052.1 - 1.9e-05 23.1 2.4 0.00053 18.3 0.1 3.9 5 1 0 5 5 5 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 ETS84052.1 - 0.0015 17.6 0.8 1.6 7.8 0.0 3.2 3 0 0 3 3 3 2 V-ATPase subunit H CAS_CSE1 PF03378.10 ETS84052.1 - 0.018 13.3 0.0 1.7 6.8 0.0 3.1 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus DUF2785 PF10978.3 ETS84052.1 - 0.046 13.1 1.0 17 4.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2785) DUF4042 PF13251.1 ETS84052.1 - 0.05 13.0 0.0 5.7 6.3 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) DUF3554 PF12074.3 ETS84052.1 - 0.053 12.9 0.5 1.8 7.9 0.0 3.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3554) DRIM PF07539.7 ETS84052.1 - 0.061 12.7 0.5 0.25 10.7 0.3 2.1 1 0 0 1 1 1 0 Down-regulated in metastasis Arm PF00514.18 ETS84052.1 - 0.071 12.9 11.6 2.8 7.9 0.0 5.6 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Cyanate_lyase PF02560.9 ETS84052.1 - 0.083 12.4 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain CBS PF00571.23 ETS84053.1 - 1.3e-14 53.6 0.9 5e-07 29.4 0.0 3.7 3 0 0 3 3 3 3 CBS domain DUF3435 PF11917.3 ETS84054.1 - 5.3e-67 226.3 2.1 7.7e-67 225.8 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) AT_hook PF02178.14 ETS84055.1 - 0.0023 17.3 19.4 0.043 13.4 2.7 2.4 2 0 0 2 2 2 2 AT hook motif NAD_binding_6 PF08030.7 ETS84060.1 - 0.00017 21.4 0.0 0.00084 19.2 0.0 1.9 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 ETS84060.1 - 0.0004 20.4 9.5 0.0004 20.4 6.6 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Pkinase PF00069.20 ETS84061.1 - 3.5e-16 59.1 0.1 6.9e-16 58.1 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS84061.1 - 3.3e-11 42.7 0.0 4.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 ETS84061.1 - 4.8e-06 25.7 0.1 7.5e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Melibiase PF02065.13 ETS84061.1 - 0.14 10.8 0.1 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Melibiase DUF3271 PF11675.3 ETS84062.1 - 0.016 14.3 1.0 0.029 13.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Hid1 PF12722.2 ETS84062.1 - 0.087 10.4 7.8 0.12 10.0 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.5 ETS84062.1 - 0.55 9.2 30.6 0.84 8.6 21.2 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.10 ETS84062.1 - 1.3 7.5 5.8 1.8 7.1 4.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 ETS84062.1 - 3.1 5.5 42.0 4.8 4.9 29.1 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 ETS84064.1 - 0.00027 19.5 2.3 0.00043 18.9 1.6 1.2 1 0 0 1 1 1 1 Daxx Family Trypan_PARP PF05887.6 ETS84064.1 - 0.022 14.5 0.9 0.033 14.0 0.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 ETS84064.1 - 0.061 11.2 7.6 0.068 11.0 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS84064.1 - 0.1 10.6 4.7 0.11 10.4 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NESP55 PF06390.7 ETS84064.1 - 0.2 10.9 4.4 0.34 10.2 3.1 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DARPP-32 PF05395.7 ETS84064.1 - 3.1 7.9 7.6 4.6 7.3 5.3 1.4 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 SDA1 PF05285.7 ETS84064.1 - 7.5 5.7 12.6 10 5.2 8.8 1.2 1 0 0 1 1 1 0 SDA1 HD_3 PF13023.1 ETS84066.1 - 9.2e-31 106.8 0.0 1.6e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.17 ETS84066.1 - 1.7e-06 28.0 0.0 4.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 HD domain ADK PF00406.17 ETS84066.1 - 0.00022 21.1 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase HD_3 PF13023.1 ETS84067.1 - 4.5e-45 153.3 0.1 6.4e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 ETS84067.1 - 2.8e-05 24.1 0.0 5.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 HD domain Mito_fiss_reg PF05308.6 ETS84068.1 - 0.28 10.5 9.3 0.3 10.4 6.0 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 ETS84068.1 - 3.6 6.7 8.1 4.7 6.3 5.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_23 PF13489.1 ETS84069.1 - 1.1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84069.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS84069.1 - 0.0017 18.8 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS84069.1 - 0.0023 18.4 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84069.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyoxal_oxid_N PF07250.6 ETS84069.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus TMF_TATA_bd PF12325.3 ETS84071.1 - 0.0012 18.5 5.5 0.0025 17.5 3.8 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 ETS84071.1 - 0.0047 17.2 7.8 0.021 15.2 5.4 2.2 1 1 0 1 1 1 1 SlyX CENP-Q PF13094.1 ETS84071.1 - 0.0066 16.4 3.9 0.0066 16.4 2.7 1.7 2 0 0 2 2 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL6 PF01763.11 ETS84071.1 - 0.01 14.0 4.5 0.01 14.0 2.5 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like GAS PF13851.1 ETS84071.1 - 0.011 14.8 4.3 0.023 13.8 3.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 ETS84071.1 - 0.014 13.3 2.8 0.018 12.8 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 ETS84071.1 - 0.017 14.8 7.5 0.31 10.8 1.4 3.2 2 1 1 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 ETS84071.1 - 0.027 14.1 4.4 0.053 13.1 3.1 1.5 1 0 0 1 1 1 0 Mnd1 family DUF641 PF04859.7 ETS84071.1 - 0.034 13.9 0.9 0.29 10.8 0.9 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 ETS84071.1 - 0.036 13.6 8.6 0.068 12.7 6.0 1.4 1 0 0 1 1 1 0 IncA protein HemX PF04375.9 ETS84071.1 - 0.046 12.3 3.1 0.078 11.5 2.2 1.3 1 0 0 1 1 1 0 HemX TMEM192 PF14802.1 ETS84071.1 - 0.051 12.4 0.7 0.08 11.7 0.5 1.3 1 0 0 1 1 1 0 TMEM192 family CENP-F_leu_zip PF10473.4 ETS84071.1 - 0.052 13.4 9.4 0.028 14.2 4.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.11 ETS84071.1 - 0.077 13.2 2.9 0.17 12.1 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3373 PF11853.3 ETS84071.1 - 0.077 11.5 1.0 0.11 11.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Phage_GP20 PF06810.6 ETS84071.1 - 0.087 12.2 2.7 0.17 11.2 1.8 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Bap31 PF05529.7 ETS84071.1 - 0.14 11.6 1.0 0.24 10.8 0.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 ETS84071.1 - 0.19 10.6 5.5 0.33 9.8 3.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 ETS84071.1 - 0.28 11.2 5.7 0.11 12.5 2.0 1.7 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 ETS84071.1 - 0.33 9.3 1.9 0.51 8.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 ETS84071.1 - 0.35 11.3 9.9 13 6.2 4.6 3.8 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.8 ETS84071.1 - 0.55 10.2 7.4 4 7.4 4.4 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.10 ETS84071.1 - 1.3 8.5 9.0 0.061 12.8 2.2 1.9 2 0 0 2 2 1 0 Septum formation initiator ABC_tran_2 PF12848.2 ETS84071.1 - 3.5 7.5 8.1 0.88 9.4 2.7 2.0 2 0 0 2 2 2 0 ABC transporter Rifin_STEVOR PF02009.11 ETS84072.1 - 3.1 7.3 11.0 4.3 6.9 7.6 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF3450 PF11932.3 ETS84074.1 - 0.00051 19.3 5.0 0.00066 19.0 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HAUS5 PF14817.1 ETS84074.1 - 0.0011 17.6 2.9 0.0011 17.6 2.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Rootletin PF15035.1 ETS84074.1 - 0.0027 17.7 4.1 0.0032 17.4 2.8 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.4 ETS84074.1 - 0.0033 16.0 2.4 0.0044 15.6 1.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 HALZ PF02183.13 ETS84074.1 - 0.0055 16.3 5.2 0.054 13.2 0.7 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 ETS84074.1 - 0.0059 16.5 5.7 0.016 15.1 0.5 2.4 1 1 1 2 2 2 1 bZIP transcription factor FlxA PF14282.1 ETS84074.1 - 0.022 14.7 2.4 0.044 13.7 1.6 1.5 1 0 0 1 1 1 0 FlxA-like protein TMCO5 PF14992.1 ETS84074.1 - 0.024 13.7 2.4 0.033 13.3 1.7 1.1 1 0 0 1 1 1 0 TMCO5 family Prominin PF05478.6 ETS84074.1 - 0.028 11.9 0.4 0.034 11.7 0.3 1.2 1 0 0 1 1 1 0 Prominin DUF465 PF04325.8 ETS84074.1 - 0.034 13.8 0.4 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) APG6 PF04111.7 ETS84074.1 - 0.066 12.2 2.6 0.077 12.0 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SPX PF03105.14 ETS84074.1 - 0.075 12.8 1.8 0.1 12.3 1.3 1.2 1 0 0 1 1 1 0 SPX domain IncA PF04156.9 ETS84074.1 - 0.078 12.5 2.6 0.11 12.0 1.8 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 ETS84074.1 - 0.15 11.9 4.5 1 9.1 3.1 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Maf1 PF09174.5 ETS84074.1 - 0.19 11.5 2.1 0.25 11.1 1.5 1.1 1 0 0 1 1 1 0 Maf1 regulator DUF3552 PF12072.3 ETS84074.1 - 0.22 10.7 8.2 0.29 10.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CorA PF01544.13 ETS84074.1 - 0.32 9.9 3.7 0.41 9.6 2.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Snf7 PF03357.16 ETS84074.1 - 0.35 10.2 4.5 0.61 9.4 3.1 1.4 1 0 0 1 1 1 0 Snf7 ABC_tran_2 PF12848.2 ETS84074.1 - 0.4 10.5 6.0 2.2 8.1 0.1 2.2 1 1 1 2 2 2 0 ABC transporter FlaC_arch PF05377.6 ETS84074.1 - 0.41 10.5 7.9 4.1 7.3 0.5 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 ETS84074.1 - 0.44 11.0 5.1 0.17 12.3 1.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 ETS84074.1 - 0.5 10.1 5.2 0.19 11.5 0.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 ETS84074.1 - 0.95 9.2 8.4 1.2 8.9 2.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2312 PF10073.4 ETS84074.1 - 0.97 8.8 5.1 1.1 8.6 2.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3186 PF11382.3 ETS84074.1 - 1.6 7.8 4.2 2.7 7.0 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) OEP PF02321.13 ETS84074.1 - 2.2 7.8 7.6 2.9 7.4 5.3 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein Kinetocho_Slk19 PF12709.2 ETS84074.1 - 2.2 8.4 6.0 1.3 9.1 0.8 2.4 1 1 1 2 2 2 0 Central kinetochore-associated DUF2852 PF11014.3 ETS84074.1 - 2.3 8.1 5.2 1 9.3 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) bZIP_2 PF07716.10 ETS84074.1 - 3 7.7 12.0 3.5 7.5 1.7 2.4 1 1 0 2 2 2 0 Basic region leucine zipper DUF2730 PF10805.3 ETS84075.1 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 ETS84075.1 - 0.024 13.8 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 ETS84075.1 - 0.055 13.7 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 ETS84075.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 ETS84075.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LRR_4 PF12799.2 ETS84079.1 - 0.55 9.9 3.6 0.88 9.2 0.0 3.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF2564 PF10819.3 ETS84081.1 - 0.036 14.1 0.2 0.061 13.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) MSP7_C PF12948.2 ETS84081.1 - 0.047 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain DUF3723 PF12520.3 ETS84083.1 - 1.1e-65 222.1 0.2 1.8e-61 208.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.20 ETS84085.1 - 7.8e-19 67.8 0.0 1.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS84085.1 - 1.5e-07 30.7 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS84085.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1703 PF08011.6 ETS84086.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) TMEM237 PF15383.1 ETS84091.1 - 0.053 12.6 1.0 0.068 12.2 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Folliculin PF11704.3 ETS84093.1 - 0.11 12.1 0.2 0.17 11.4 0.1 1.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1338 PF07063.8 ETS84094.1 - 9.9e-79 264.5 0.0 1.5e-78 263.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyoxalase_4 PF13669.1 ETS84094.1 - 0.049 13.6 0.0 1.5 8.8 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aldedh PF00171.17 ETS84095.1 - 4.4e-150 500.0 0.0 5.4e-150 499.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_3 PF07859.8 ETS84096.1 - 3.8e-21 75.6 0.3 9.9e-21 74.2 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS84096.1 - 6e-17 61.5 0.7 1.9e-16 59.8 0.5 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS84096.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS84096.1 - 1.6e-06 27.9 0.1 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS84096.1 - 0.00068 19.5 0.1 0.00097 19.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS84096.1 - 0.00071 18.3 0.0 0.00097 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_M9_N PF08453.5 ETS84096.1 - 0.16 11.3 0.2 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Ribonuc_L-PSP PF01042.16 ETS84097.1 - 1.7e-22 79.4 0.1 2.8e-22 78.7 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_3 PF01494.14 ETS84098.1 - 4.5e-19 68.7 0.7 2.6e-14 53.0 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS84098.1 - 0.0082 15.0 0.1 0.19 10.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 ETS84098.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 ETS84098.1 - 0.027 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 ETS84098.1 - 0.046 13.3 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III PF08545.5 ETS84098.1 - 0.14 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cupin_2 PF07883.6 ETS84099.1 - 5e-15 54.7 0.0 2.7e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Fungal_trans PF04082.13 ETS84100.1 - 4.2e-22 78.2 0.0 7.3e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84100.1 - 1e-07 31.7 7.3 1e-07 31.7 5.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.9 ETS84100.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Dynamitin Amidohydro_2 PF04909.9 ETS84101.1 - 1.4e-44 152.7 0.0 1.6e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 ETS84102.1 - 1.4e-94 317.2 25.9 1.7e-94 316.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84102.1 - 1.4e-18 66.7 29.7 1.4e-18 66.7 20.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS84102.1 - 0.061 11.7 26.3 0.077 11.3 7.4 2.9 1 1 1 2 2 2 0 MFS/sugar transport protein TMEM138 PF14935.1 ETS84102.1 - 0.11 12.8 1.3 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 138 NADH_dehy_S2_C PF06444.6 ETS84102.1 - 0.11 12.7 1.1 0.33 11.2 0.7 1.9 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Cellulase PF00150.13 ETS84103.1 - 4.6e-18 65.4 0.5 9.9e-18 64.3 0.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.8 ETS84103.1 - 0.0084 14.9 0.1 1.1 7.9 0.0 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 53 COesterase PF00135.23 ETS84104.1 - 8.2e-88 295.4 0.0 2.7e-80 270.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS84104.1 - 6.9e-06 25.7 0.0 3.9e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84104.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84104.1 - 0.048 13.2 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS84104.1 - 0.052 12.7 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SOG2 PF10428.4 ETS84105.1 - 0.02 13.5 2.1 0.03 13.0 1.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-CCHC PF00098.18 ETS84106.1 - 1.7e-45 150.8 57.2 3.9e-08 32.8 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 ETS84106.1 - 1.4e-10 40.6 40.8 0.072 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 ETS84106.1 - 9e-07 28.5 41.8 0.016 14.9 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 ETS84106.1 - 0.024 14.3 47.7 0.068 12.8 0.2 6.9 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 ETS84106.1 - 0.064 12.7 0.3 0.064 12.7 0.2 7.2 4 2 3 7 7 7 0 Zinc knuckle WD40 PF00400.27 ETS84108.1 - 5e-51 168.8 2.1 2.6e-08 33.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 ETS84108.1 - 0.00077 18.3 1.6 0.74 8.4 0.2 2.9 1 1 1 2 2 2 2 Nup133 N terminal like OapA PF04225.7 ETS84108.1 - 0.13 12.2 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain TRAPP PF04051.11 ETS84109.1 - 3.1e-37 127.4 0.1 3.6e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LisH PF08513.6 ETS84110.1 - 5.3e-05 22.8 1.0 9.4e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 LisH Glyco_hydro_16 PF00722.16 ETS84111.1 - 1.3e-12 47.4 0.0 2.2e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 ETS84111.1 - 8.4e-08 30.8 0.2 0.0027 15.9 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) GTP_EFTU PF00009.22 ETS84112.1 - 4.9e-50 169.5 0.0 7.7e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 ETS84112.1 - 1.1e-39 134.6 4.4 1.8e-39 133.9 3.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 ETS84112.1 - 3.2e-18 65.3 0.0 6.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 ETS84112.1 - 8.7e-07 28.4 0.0 2.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.20 ETS84112.1 - 4.3e-06 26.7 0.1 1.2e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS84112.1 - 2.3e-05 24.3 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 ETS84112.1 - 0.002 17.9 0.0 0.0056 16.4 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 ETS84112.1 - 0.0084 15.3 0.0 0.023 13.9 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Lipase_GDSL PF00657.17 ETS84113.1 - 1.4e-10 41.4 0.7 2e-10 40.9 0.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 ETS84113.1 - 7.7e-10 39.1 0.7 1.1e-09 38.6 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ring_hydroxyl_A PF00848.14 ETS84115.1 - 3.7e-34 118.2 2.8 2e-33 115.8 1.9 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS84115.1 - 5.5e-14 51.5 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 ETS84116.1 - 1.5e-20 74.1 0.0 8.1e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84116.1 - 3.5e-12 45.2 0.0 9.2e-12 43.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS84116.1 - 3.3e-07 29.5 0.1 3.4e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 ETS84117.1 - 3.4e-16 58.9 28.9 1.5e-11 43.6 9.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1656 PF07869.7 ETS84117.1 - 0.0077 15.9 0.7 0.0077 15.9 0.5 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1656) DAO PF01266.19 ETS84118.1 - 1.2e-46 159.3 0.1 1.4e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS84118.1 - 6.1e-07 29.3 0.0 4e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS84118.1 - 5.9e-06 26.3 0.1 0.097 12.5 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS84118.1 - 7.2e-06 26.2 0.0 0.054 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS84118.1 - 7.1e-05 21.8 0.4 0.00054 18.9 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS84118.1 - 8.8e-05 21.5 0.3 0.0039 16.0 0.1 2.5 2 1 1 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 ETS84118.1 - 0.0002 19.9 0.0 0.2 10.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 ETS84118.1 - 0.0019 18.5 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS84118.1 - 0.0045 16.7 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS84118.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 ETS84118.1 - 0.046 13.9 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GMC_oxred_N PF00732.14 ETS84118.1 - 0.062 12.4 0.1 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Shikimate_DH PF01488.15 ETS84118.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 ETS84118.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 ETS84118.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 ETS84118.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_4 PF01565.18 ETS84119.1 - 3.1e-20 72.0 1.2 6e-20 71.1 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS84119.1 - 0.031 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like FAD-oxidase_C PF02913.14 ETS84119.1 - 0.049 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain NmrA PF05368.8 ETS84120.1 - 0.0011 18.2 0.1 0.075 12.2 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 ETS84120.1 - 0.0025 17.8 0.6 0.24 11.4 0.2 2.4 1 1 1 2 2 2 2 NADH(P)-binding 7TMR-HDED PF07697.6 ETS84120.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 7TM-HD extracellular Hydantoinase_B PF02538.9 ETS84121.1 - 6.1e-183 608.8 0.0 8.2e-183 608.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 ETS84121.1 - 4.5e-81 272.1 0.0 8.4e-81 271.2 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS84121.1 - 3.8e-54 182.8 0.0 1.3e-52 177.8 0.0 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 ETS84122.1 - 1.7e-31 109.2 29.7 1.7e-31 109.2 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS84123.1 - 9.5e-32 109.8 0.1 1.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84123.1 - 9.8e-06 25.3 12.2 1.6e-05 24.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 ETS84124.1 - 8.4e-40 135.8 0.0 1.1e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS84124.1 - 1.7e-09 37.2 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS84124.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_CoxI PF02625.11 ETS84124.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 XdhC and CoxI family Peptidase_M20 PF01546.23 ETS84125.1 - 8.4e-22 77.5 0.1 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS84125.1 - 2.5e-16 59.4 0.0 7.9e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS84125.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 2OG-FeII_Oxy PF03171.15 ETS84126.1 - 3.1e-11 43.4 0.0 6.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS84126.1 - 2e-06 28.3 0.0 3.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 ETS84127.1 - 0.069 11.8 0.1 0.091 11.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.11 ETS84128.1 - 7.4e-25 87.3 26.3 5.6e-24 84.4 19.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1191 PF06697.7 ETS84128.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Pyr_redox_3 PF13738.1 ETS84129.1 - 9.8e-20 71.4 0.0 2.5e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84129.1 - 1.1e-10 40.3 0.4 1.7e-07 29.8 0.3 2.9 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS84129.1 - 1.3e-06 28.3 0.0 3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84129.1 - 4.8e-06 25.7 0.0 0.0079 15.1 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS84129.1 - 0.0047 16.7 0.0 0.54 10.0 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS84129.1 - 0.037 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS84129.1 - 0.044 13.6 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DHDPS PF00701.17 ETS84130.1 - 5.6e-47 159.7 0.0 6.8e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 ETS84130.1 - 0.0009 18.5 0.1 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_1_2 PF00155.16 ETS84131.1 - 4.5e-71 239.7 0.0 5.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans PF04082.13 ETS84132.1 - 4.3e-17 61.8 2.0 9e-17 60.8 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S29 PF02907.10 ETS84132.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease NAD_binding_2 PF03446.10 ETS84133.1 - 5.9e-23 81.4 0.1 9.1e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS84133.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 ETS84133.1 - 0.023 14.7 0.0 0.053 13.6 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 ETS84134.1 - 3.9e-05 22.6 0.1 0.0012 17.7 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84134.1 - 0.023 14.5 0.4 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1446 PF07287.6 ETS84135.1 - 9.4e-122 405.9 0.0 1.1e-121 405.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) ADH_N PF08240.7 ETS84136.1 - 1.4e-10 40.8 0.0 4.8e-08 32.7 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS84136.1 - 1e-08 34.7 0.2 2.2e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 ETS84137.1 - 2.2e-25 89.8 0.0 2.7e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84137.1 - 1.2e-11 44.6 0.1 4.2e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84137.1 - 9.1e-10 38.4 0.1 2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS84137.1 - 6.7e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 ETS84137.1 - 0.0039 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 ETS84137.1 - 0.063 12.1 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Bac_luciferase PF00296.15 ETS84138.1 - 1.7e-59 201.4 1.5 2.5e-59 200.9 1.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase LamB_YcsF PF03746.11 ETS84139.1 - 2e-56 190.7 0.6 3e-56 190.2 0.3 1.3 2 0 0 2 2 2 1 LamB/YcsF family MFS_1 PF07690.11 ETS84140.1 - 6.5e-28 97.4 21.9 8.3e-28 97.1 15.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS84140.1 - 6.5e-06 25.7 1.8 6.5e-06 25.7 1.2 1.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 ETS84142.1 - 1.8e-71 240.7 0.0 2.3e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84142.1 - 1.5e-13 51.5 0.2 4.7e-13 49.8 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 ETS84143.1 - 3.8e-20 71.6 0.8 7.2e-20 70.7 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS84143.1 - 9e-14 51.1 0.0 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS84143.1 - 7.1e-09 36.6 0.0 1.6e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 ETS84144.1 - 1.7e-24 87.0 0.0 3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84144.1 - 2.4e-15 55.7 0.1 1.1e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS84144.1 - 4.2e-09 36.5 0.0 1e-06 28.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84144.1 - 1.3e-07 31.5 0.2 5.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84144.1 - 1.5e-07 30.6 0.0 6.6e-05 21.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS84144.1 - 0.0011 18.0 1.4 0.012 14.5 0.7 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS84144.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS84144.1 - 0.0026 17.5 1.1 0.38 10.5 0.1 3.8 4 1 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS84144.1 - 0.0079 15.3 0.1 0.055 12.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 ETS84144.1 - 0.022 13.2 0.1 0.057 11.8 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS84144.1 - 0.027 13.4 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 ETS84144.1 - 0.036 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 ETS84144.1 - 0.073 12.1 0.1 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 ETS84144.1 - 0.088 12.9 0.0 0.95 9.5 0.0 2.6 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 ETS84145.1 - 4.6e-22 79.0 0.0 4.2e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84145.1 - 2.5e-17 62.2 0.0 2e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS84145.1 - 2.4e-09 37.0 0.0 9.5e-09 35.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84145.1 - 1.4e-06 27.4 0.0 6.5e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS84145.1 - 0.00085 19.1 0.4 0.075 12.7 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 ETS84145.1 - 0.024 13.7 0.0 0.52 9.3 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.13 ETS84146.1 - 9.1e-18 64.0 0.0 1.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84146.1 - 0.00011 22.0 12.0 0.00021 21.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.1 ETS84146.1 - 0.25 10.9 5.8 0.47 10.1 4.0 1.4 1 0 0 1 1 1 0 Cytochrome c7 MFS_1 PF07690.11 ETS84147.1 - 8.4e-34 116.8 32.6 8.4e-34 116.8 22.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS84147.1 - 0.018 15.0 0.1 0.018 15.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Lactamase_B PF00753.22 ETS84148.1 - 1.3e-08 34.7 0.5 2e-08 34.1 0.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS84148.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 ETS84149.1 - 6.6e-16 58.6 0.0 1.4e-15 57.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84149.1 - 3.8e-06 26.6 0.0 0.002 17.8 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 ETS84149.1 - 0.0031 17.3 0.2 0.29 10.8 0.0 2.7 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase His_Phos_1 PF00300.17 ETS84150.1 - 3.4e-17 62.9 0.0 4.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gmx_para_CXXCG PF09535.5 ETS84150.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) CTNNBL PF08216.6 ETS84151.1 - 1.6e-34 117.7 0.1 8.5e-33 112.1 0.0 3.1 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear GP46 PF07409.7 ETS84151.1 - 0.0077 15.5 1.3 0.19 11.0 0.1 2.4 2 0 0 2 2 2 2 Phage protein GP46 V-ATPase_G PF03179.10 ETS84152.1 - 3e-23 82.1 12.9 3.5e-23 81.8 9.0 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3584 PF12128.3 ETS84152.1 - 0.032 11.5 4.4 0.034 11.4 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nop25 PF09805.4 ETS84152.1 - 0.056 13.5 11.8 0.082 12.9 8.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF222 PF02720.12 ETS84152.1 - 0.062 12.4 0.4 0.069 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF222) YusW PF14039.1 ETS84152.1 - 0.067 13.4 5.0 0.094 13.0 3.5 1.2 1 0 0 1 1 1 0 YusW-like protein DUF87 PF01935.12 ETS84152.1 - 0.068 12.9 0.3 0.077 12.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 Rifin_STEVOR PF02009.11 ETS84152.1 - 0.071 12.7 3.5 0.081 12.5 2.4 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2201_N PF13203.1 ETS84152.1 - 0.15 11.2 2.7 0.18 10.9 1.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HAUS6_N PF14661.1 ETS84152.1 - 0.26 10.6 3.6 0.28 10.5 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Hom_end_hint PF05203.11 ETS84152.1 - 0.29 10.8 4.2 0.37 10.5 2.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Atg14 PF10186.4 ETS84152.1 - 0.39 9.6 3.1 0.47 9.3 2.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vfa1 PF08432.5 ETS84152.1 - 0.53 10.2 9.4 0.62 10.0 6.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3987 PF13148.1 ETS84152.1 - 0.61 8.5 6.5 0.81 8.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4407 PF14362.1 ETS84152.1 - 1.7 7.5 6.2 2 7.2 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TSA PF03249.8 ETS84152.1 - 2.7 6.4 5.6 3.2 6.2 3.9 1.0 1 0 0 1 1 1 0 Type specific antigen RRF PF01765.14 ETS84152.1 - 4.1 6.8 13.0 5.5 6.4 8.9 1.3 1 1 0 1 1 1 0 Ribosome recycling factor ATP-synt_B PF00430.13 ETS84152.1 - 5.8 6.7 13.6 18 5.1 9.4 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4337 PF14235.1 ETS84152.1 - 6.5 6.5 8.4 8.3 6.2 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_Rpb1_6 PF04992.9 ETS84153.1 - 0.063 13.0 0.5 0.071 12.8 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Acetyltransf_1 PF00583.19 ETS84154.1 - 2.8e-09 36.8 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS84154.1 - 1.1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS84154.1 - 2.6e-08 33.7 0.0 3.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS84154.1 - 0.00011 22.2 0.0 0.00092 19.3 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS84154.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 ETS84154.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PhyH PF05721.8 ETS84155.1 - 1.1e-09 38.6 0.0 8e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) E1-E2_ATPase PF00122.15 ETS84156.1 - 3.3e-05 23.0 0.1 0.14 11.1 0.0 2.2 1 1 1 2 2 2 2 E1-E2 ATPase DUF835 PF05763.7 ETS84156.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF835) CECR6_TMEM121 PF14997.1 ETS84157.1 - 0.058 13.0 1.1 0.092 12.3 0.8 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family Frag1 PF10277.4 ETS84157.1 - 0.065 12.6 7.2 0.099 12.1 5.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family ABC2_membrane PF01061.19 ETS84157.1 - 1.2 8.2 10.8 1.8 7.7 7.5 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Abhydrolase_6 PF12697.2 ETS84158.1 - 1.1e-09 38.5 1.6 1.4e-09 38.1 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84158.1 - 0.0042 16.6 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84158.1 - 0.008 15.9 0.1 0.022 14.5 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 ETS84159.1 - 7.4e-09 35.4 0.0 2e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 ETS84159.1 - 0.00029 21.1 0.6 0.023 15.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS84159.1 - 0.0068 16.5 0.1 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 ETS84159.1 - 0.0069 16.7 0.6 0.29 11.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84159.1 - 0.01 15.6 0.1 3.9 7.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat AAA PF00004.24 ETS84159.1 - 0.017 15.3 0.0 0.096 12.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_4 PF13894.1 ETS84159.1 - 5.4 7.5 7.6 10 6.7 2.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.18 ETS84160.1 - 1.1e-67 227.9 0.0 1.7e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS84160.1 - 4.4e-12 45.7 0.8 1.7e-11 43.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS84160.1 - 0.00059 19.7 0.0 0.0027 17.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DZR PF12773.2 ETS84160.1 - 0.044 13.5 1.4 0.15 11.9 1.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon adh_short PF00106.20 ETS84161.1 - 3.2e-16 59.7 0.6 8e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS84161.1 - 5.3e-08 32.7 1.2 1.6e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS84161.1 - 0.00014 21.3 0.0 0.00032 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 ETS84161.1 - 0.00024 20.9 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-grasp_5 PF13549.1 ETS84161.1 - 0.025 13.8 0.0 0.083 12.0 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Shikimate_DH PF01488.15 ETS84161.1 - 0.034 14.2 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_S28 PF05577.7 ETS84162.1 - 3.5e-46 157.6 0.7 1.2e-45 155.9 0.5 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 ETS84162.1 - 1.1e-07 30.6 0.3 0.00087 17.8 0.0 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 Abhydrolase_6 PF12697.2 ETS84162.1 - 0.001 18.9 0.3 0.0038 17.1 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family ATP-synt_B PF00430.13 ETS84163.1 - 0.072 12.8 33.9 0.37 10.5 6.4 3.7 1 1 3 4 4 4 0 ATP synthase B/B' CF(0) zf-C2H2_6 PF13912.1 ETS84163.1 - 0.13 12.1 5.5 77 3.4 0.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger Pilt PF15453.1 ETS84163.1 - 1.7 8.2 23.9 0.99 9.0 9.7 2.1 1 1 1 2 2 2 0 Protein incorporated later into Tight Junctions DUF2856 PF11043.3 ETS84163.1 - 4.6 7.4 6.0 4.6 7.4 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2856) DUF501 PF04417.7 ETS84163.1 - 7.4 6.4 32.5 4.2 7.2 3.9 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF501) DUF3554 PF12074.3 ETS84164.1 - 6e-80 269.2 8.0 1.6e-79 267.8 1.8 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 ETS84164.1 - 4.1e-37 122.9 46.4 0.02 14.9 0.1 23.7 27 0 0 27 27 27 8 HEAT repeat HEAT_2 PF13646.1 ETS84164.1 - 2.6e-35 120.5 55.2 2.2e-09 37.4 0.0 17.3 11 3 6 17 17 17 7 HEAT repeats HEAT_EZ PF13513.1 ETS84164.1 - 2.3e-33 113.8 62.1 2.6e-06 27.7 0.0 22.9 18 7 8 26 26 26 12 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS84164.1 - 1.1e-16 60.9 0.0 0.17 12.2 0.0 9.1 6 2 1 7 7 7 4 Vacuolar 14 Fab1-binding region ParcG PF10274.4 ETS84164.1 - 6.3e-12 45.7 0.4 0.00019 21.4 0.0 5.8 5 1 0 5 5 5 3 Parkin co-regulated protein CLASP_N PF12348.3 ETS84164.1 - 1.1e-11 44.6 0.0 0.021 14.1 0.0 6.2 4 1 3 7 7 7 3 CLASP N terminal Cnd1 PF12717.2 ETS84164.1 - 7.1e-11 42.2 0.0 4.3 7.1 0.0 8.9 6 3 1 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 ETS84164.1 - 0.0001 22.1 0.6 0.013 15.4 0.0 5.0 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation DUF3896 PF13035.1 ETS84164.1 - 1.7 8.7 3.4 5.1 7.2 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) HA2 PF04408.18 ETS84165.1 - 3.2e-19 68.8 0.1 1.2e-18 66.9 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS84165.1 - 5.5e-15 54.9 0.1 1.3e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS84165.1 - 6.7e-10 38.7 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS84165.1 - 2.1e-08 34.3 1.0 1.5e-06 28.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.11 ETS84165.1 - 3e-07 30.2 0.0 7.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold NB-ARC PF00931.17 ETS84165.1 - 0.002 17.0 0.0 0.0053 15.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 ETS84165.1 - 0.015 15.5 0.2 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 ETS84165.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 ETS84165.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 ETS84165.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cutinase PF01083.17 ETS84166.1 - 4.6e-46 156.7 0.2 5.6e-46 156.5 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS84166.1 - 0.00055 19.4 0.2 0.00087 18.7 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 ETS84166.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 ETS84166.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 ETS84166.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Alpha_GJ PF03229.8 ETS84167.1 - 0.0016 18.7 2.3 0.0016 18.7 1.6 1.5 2 0 0 2 2 2 1 Alphavirus glycoprotein J TMEM154 PF15102.1 ETS84167.1 - 0.028 14.1 0.2 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Alkyl_sulf_dimr PF14863.1 ETS84168.1 - 2.1e-54 183.6 0.0 3.3e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 ETS84168.1 - 9.5e-19 67.8 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 ETS84168.1 - 1.4e-18 67.0 0.1 3.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 ETS84168.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 ETS84168.1 - 0.043 13.4 0.4 0.25 11.0 0.0 2.3 3 0 0 3 3 3 0 TPR repeat SCP2 PF02036.12 ETS84168.1 - 0.05 13.9 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family TPR_16 PF13432.1 ETS84168.1 - 0.37 11.5 2.3 0.84 10.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS84169.1 - 2.7e-46 157.8 57.2 1.1e-38 132.8 23.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF912 PF06024.7 ETS84169.1 - 0.6 10.1 2.6 8.1 6.5 0.0 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Kinetocho_Slk19 PF12709.2 ETS84170.1 - 9.1 6.4 9.7 0.66 10.0 0.2 3.5 3 1 1 4 4 4 0 Central kinetochore-associated Aconitase PF00330.15 ETS84171.1 - 3e-63 213.9 0.0 5.9e-41 140.4 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS84171.1 - 4.2e-14 52.7 0.0 7.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 ETS84171.1 - 0.0021 17.4 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Fungal_trans_2 PF11951.3 ETS84172.1 - 2.9e-37 128.1 4.3 3.7e-37 127.8 3.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84172.1 - 1.7e-08 34.1 9.9 1.7e-08 34.1 6.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase PF03211.8 ETS84173.1 - 3.4e-75 252.1 2.0 4.1e-75 251.8 1.4 1.0 1 0 0 1 1 1 1 Pectate lyase FMN_dh PF01070.13 ETS84174.1 - 5.2e-119 397.2 0.0 6.1e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS84174.1 - 3.4e-07 29.4 0.1 6.4e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 ETS84174.1 - 0.00015 21.1 0.1 0.0026 17.0 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 ETS84174.1 - 0.00022 20.2 0.1 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 ETS84174.1 - 0.012 14.5 0.1 0.024 13.6 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 ETS84174.1 - 0.023 13.7 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 ETS84174.1 - 0.03 13.4 0.1 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Aldedh PF00171.17 ETS84175.1 - 4.6e-184 612.0 0.4 5.2e-184 611.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS84175.1 - 0.0016 17.2 0.0 0.0031 16.3 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS84175.1 - 0.14 11.3 0.0 0.71 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DHDPS PF00701.17 ETS84176.1 - 1.4e-62 210.9 0.0 1.6e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Epimerase PF01370.16 ETS84177.1 - 9.1e-10 38.3 0.0 1.4e-06 27.8 0.0 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS84177.1 - 4.3e-07 28.9 0.0 8.1e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS84177.1 - 4.2e-06 25.8 0.0 6.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 ETS84177.1 - 1e-05 24.8 0.0 5.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 ETS84177.1 - 0.00018 20.5 0.0 0.00053 18.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 ETS84177.1 - 0.00019 21.3 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 ETS84177.1 - 0.00065 19.7 0.1 0.0016 18.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS84177.1 - 0.0018 17.3 0.1 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS84177.1 - 0.0078 16.5 0.0 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain IDO PF01231.13 ETS84179.1 - 1.4e-165 550.8 0.0 1.7e-165 550.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 ETS84180.1 - 1.5e-37 127.9 0.0 2.4e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 ETS84180.1 - 1.7e-21 75.5 0.0 3.7e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 ETS84180.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Strabismus PF06638.6 ETS84181.1 - 0.21 9.8 2.8 0.34 9.1 2.0 1.2 1 0 0 1 1 1 0 Strabismus protein DUF1682 PF07946.9 ETS84181.1 - 7.2 5.3 10.8 11 4.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Methyltransf_23 PF13489.1 ETS84182.1 - 4.4e-22 78.5 0.0 6.7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84182.1 - 7.1e-09 35.4 0.0 2.3e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS84182.1 - 1.9e-08 34.6 0.0 8.6e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS84182.1 - 5.1e-08 33.2 0.0 8.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84182.1 - 1.6e-07 31.8 0.0 8.1e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS84182.1 - 0.0035 17.6 0.0 0.0093 16.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS84182.1 - 0.0035 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 ETS84182.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 ETS84182.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 ETS84182.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.7 2 1 0 2 2 1 0 Methyltransferase domain FtsJ PF01728.14 ETS84182.1 - 0.054 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 ETS84182.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS84182.1 - 0.092 11.8 0.0 0.7 8.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNA_pol_Rpb2_6 PF00562.23 ETS84183.1 - 1.9e-125 418.6 0.2 7.5e-125 416.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ETS84183.1 - 3.2e-57 192.7 0.0 5e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 ETS84183.1 - 2.7e-47 160.6 0.0 5.5e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 ETS84183.1 - 3.5e-30 104.0 0.0 7.7e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 ETS84183.1 - 3.8e-25 87.5 0.4 9.6e-25 86.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 ETS84183.1 - 1.1e-22 79.5 0.1 3.1e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 ETS84183.1 - 3.9e-21 74.6 0.1 1.1e-20 73.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 STE2 PF02116.10 ETS84185.1 - 5.2e-31 107.7 10.8 6.3e-31 107.4 7.5 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR FAD_binding_3 PF01494.14 ETS84187.1 - 1.7e-20 73.4 0.0 3.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS84187.1 - 6.6e-05 22.8 1.3 0.00016 21.6 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS84187.1 - 0.0072 15.2 0.1 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ETS84187.1 - 0.0087 14.7 0.3 0.15 10.6 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS84187.1 - 0.059 12.2 0.5 0.11 11.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_3 PF07859.8 ETS84188.1 - 1.9e-28 99.4 0.1 3.3e-26 92.1 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS84188.1 - 2.9e-11 43.7 0.6 1.3e-10 41.5 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84188.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84188.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 ETS84188.1 - 0.066 11.9 0.1 0.19 10.4 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Mt_ATP-synt_D PF05873.7 ETS84189.1 - 1.4e-18 67.0 2.0 1.8e-18 66.7 1.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 ETS84189.1 - 0.021 14.7 0.2 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Dor1 PF04124.7 ETS84189.1 - 0.055 11.9 3.0 0.07 11.5 2.1 1.1 1 0 0 1 1 1 0 Dor1-like family Tropomyosin PF00261.15 ETS84189.1 - 0.06 12.4 6.8 0.082 11.9 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin Prominin PF05478.6 ETS84189.1 - 0.36 8.3 3.0 0.41 8.1 2.1 1.0 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.4 ETS84189.1 - 0.43 10.7 6.7 0.45 10.6 1.7 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 ETS84189.1 - 1.9 8.8 6.2 6.2 7.1 0.4 2.2 1 1 1 2 2 2 0 Spectrin repeat NAC PF01849.13 ETS84190.1 - 2.8e-26 90.7 0.2 2.3e-25 87.8 0.1 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 ETS84190.1 - 6.5e-05 22.6 0.1 0.00018 21.2 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HHH PF00633.18 ETS84190.1 - 0.058 13.1 0.1 10 6.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif SpoIIIAH PF12685.2 ETS84190.1 - 2.2 7.7 10.2 1.1 8.7 3.6 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein EBV-NA3 PF05009.7 ETS84190.1 - 6.9 5.8 8.6 0.63 9.2 0.5 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_L14e PF01929.12 ETS84191.1 - 4.3e-27 94.2 4.7 6.1e-27 93.7 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 ETS84191.1 - 0.00038 20.0 0.7 0.00075 19.1 0.0 1.9 2 0 0 2 2 2 1 KOW motif AMP-binding PF00501.23 ETS84192.1 - 2.8e-84 282.9 0.0 3.5e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84192.1 - 2.3e-13 50.8 1.4 6e-13 49.5 0.2 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.4 ETS84192.1 - 0.19 10.8 0.3 0.32 10.0 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Ribosomal_S14 PF00253.16 ETS84194.1 - 1.7e-16 59.3 0.7 1.7e-16 59.3 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Arb2 PF09757.4 ETS84195.1 - 7.7e-18 64.5 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain TPR_12 PF13424.1 ETS84196.1 - 0.0059 16.5 0.2 0.71 9.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Tho2 PF11262.3 ETS84196.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YtxH PF12732.2 ETS84196.1 - 0.23 11.8 1.6 0.66 10.3 0.8 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF4199 PF13858.1 ETS84197.1 - 6.4 6.6 10.4 0.4 10.5 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF2269 PF10027.4 ETS84198.1 - 0.11 12.2 7.1 0.31 10.7 0.3 2.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF2627 PF11118.3 ETS84198.1 - 2.2 8.4 6.2 2.3 8.3 2.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2627) APH PF01636.18 ETS84199.1 - 4.6e-17 62.5 0.0 1.8e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS84199.1 - 0.006 16.1 0.4 0.012 15.1 0.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETS84199.1 - 0.07 12.4 0.0 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.11 ETS84201.1 - 1.5e-31 109.4 35.0 1.5e-31 109.4 24.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily RCR PF12273.3 ETS84201.1 - 4.3 7.9 0.0 4.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red A_deaminase PF00962.17 ETS84202.1 - 4.3e-38 131.0 0.0 5.3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mpt_N PF09176.6 ETS84202.1 - 0.027 14.3 0.3 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal DUF2764 PF10962.3 ETS84202.1 - 0.084 12.0 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) HAD_2 PF13419.1 ETS84204.1 - 3.6e-24 85.9 0.0 4.5e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS84204.1 - 0.0042 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HNH PF01844.18 ETS84205.1 - 2.2e-06 27.4 0.5 5e-06 26.2 0.4 1.6 1 1 0 1 1 1 1 HNH endonuclease FYDLN_acid PF09538.5 ETS84205.1 - 0.029 14.9 2.1 0.055 14.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ank_2 PF12796.2 ETS84206.1 - 5.1e-30 103.6 0.7 1.2e-14 54.3 0.3 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84206.1 - 3.3e-26 89.7 6.6 2.2e-10 39.8 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 ETS84206.1 - 6.9e-23 78.4 3.3 7.2e-08 31.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 ETS84206.1 - 8.8e-22 77.0 1.2 3.3e-06 27.4 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84206.1 - 2.2e-15 56.2 4.3 1e-06 28.7 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) F-box-like PF12937.2 ETS84206.1 - 0.00045 19.8 0.1 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like 4HBT_3 PF13622.1 ETS84209.1 - 2.7e-27 96.1 1.3 3.4e-27 95.8 0.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 ETS84209.1 - 9.9e-12 44.6 0.0 2.3e-08 33.7 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase Cu-oxidase_3 PF07732.10 ETS84210.1 - 1.3e-40 137.8 3.2 1.3e-40 137.8 2.2 3.0 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS84210.1 - 2.2e-35 121.1 16.5 5.4e-35 119.9 0.7 4.4 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS84210.1 - 1.2e-34 119.5 0.1 4.3e-34 117.7 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase GP4 PF03010.9 ETS84210.1 - 0.047 13.3 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 GP4 Mito_carr PF00153.22 ETS84212.1 - 3.1e-59 196.7 2.9 4.8e-22 77.4 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.4 ETS84214.1 - 8.2e-87 290.3 0.0 1.3e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 ETS84214.1 - 0.058 13.6 0.2 0.26 11.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Bac_chlorC PF02043.12 ETS84214.1 - 0.12 12.2 0.3 0.34 10.7 0.2 1.8 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein PCMT PF01135.14 ETS84215.1 - 1.4e-48 165.1 0.0 1e-15 57.8 0.0 3.0 3 0 0 3 3 3 3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 ETS84215.1 - 4.2e-07 30.5 0.0 6.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84215.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS84215.1 - 0.00069 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS84215.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS84215.1 - 0.0061 16.2 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS84215.1 - 0.056 12.1 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 ETS84215.1 - 0.096 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 ETS84215.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 ETS84216.1 - 2.5e-51 174.6 0.0 3.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS84217.1 - 1.4e-29 103.0 0.1 2.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BAMBI PF06211.7 ETS84217.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Iso_dh PF00180.15 ETS84219.1 - 3.2e-129 430.8 0.0 3.7e-129 430.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 ETS84220.1 - 5.9e-08 32.2 6.4 1e-07 31.4 4.4 1.4 1 0 0 1 1 1 1 PHD-finger Glyco_hydro_92 PF07971.7 ETS84222.1 - 1.7e-153 511.9 4.7 2.1e-153 511.5 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Cu_amine_oxid PF01179.15 ETS84224.1 - 3e-153 510.4 0.0 3.7e-153 510.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 ETS84224.1 - 1.2e-11 44.4 0.0 2.9e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 ETS84224.1 - 2.7e-08 33.7 0.0 7.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.13 ETS84225.1 - 5.9e-15 54.8 7.4 8.8e-15 54.2 5.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 ETS84226.1 - 0.0082 16.1 1.7 0.032 14.2 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS84226.1 - 0.045 13.6 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS84226.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.17 ETS84227.1 - 7.6e-156 519.0 0.1 8.6e-156 518.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 ETS84227.1 - 0.096 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase AA_permease PF00324.16 ETS84228.1 - 8.7e-118 393.6 42.9 1.1e-117 393.3 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS84228.1 - 2.8e-32 111.7 50.1 3.6e-32 111.4 34.7 1.2 1 0 0 1 1 1 1 Amino acid permease SnoaL_4 PF13577.1 ETS84229.1 - 1.2e-06 28.4 0.1 1.8e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 ETS84229.1 - 6.2e-05 23.3 0.3 8.1e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS84229.1 - 0.0015 18.6 0.1 0.002 18.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Abhydrolase_1 PF00561.15 ETS84230.1 - 1.7e-16 60.4 0.1 1.1e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS84230.1 - 2.3e-10 40.7 0.3 6.1e-10 39.3 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS84230.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 ETS84230.1 - 0.031 13.7 0.1 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase adh_short PF00106.20 ETS84231.1 - 7e-34 117.1 2.0 7e-34 117.1 1.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84231.1 - 9.3e-14 51.7 0.1 1.2e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84231.1 - 1.4e-12 47.6 0.7 2.2e-12 46.9 0.5 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS84231.1 - 3.9e-06 25.7 0.3 5e-06 25.4 0.2 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 ETS84231.1 - 1.2e-05 25.0 0.2 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 ETS84231.1 - 7.8e-05 22.2 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS84231.1 - 0.0054 16.0 0.3 0.021 14.0 0.2 1.9 3 0 0 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.1 ETS84231.1 - 0.0063 16.5 1.3 0.068 13.1 0.4 2.4 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS84231.1 - 0.0089 14.9 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 ETS84231.1 - 0.039 12.8 0.1 0.065 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.18 ETS84231.1 - 0.041 13.7 0.3 0.094 12.5 0.2 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS84231.1 - 0.055 13.4 0.3 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 ETS84232.1 - 1.7e-40 138.9 0.0 2.2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-PARP PF00645.13 ETS84233.1 - 6.3e-21 74.4 0.5 1.2e-20 73.5 0.3 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Beta-lactamase PF00144.19 ETS84234.1 - 4.5e-24 85.0 0.0 8.3e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase AIG2 PF06094.7 ETS84235.1 - 9.9e-09 35.6 0.3 2.2e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 AIG2-like family DUF1620 PF07774.8 ETS84236.1 - 1.2e-67 227.4 0.0 2.3e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 ETS84236.1 - 1.7e-16 60.4 9.3 6.5e-12 45.4 3.2 2.5 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 ETS84236.1 - 6.3e-07 28.6 5.4 0.0031 16.9 0.0 5.2 7 0 0 7 7 7 3 PQQ enzyme repeat PQQ_3 PF13570.1 ETS84236.1 - 0.017 15.3 0.2 13 6.2 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain DAO PF01266.19 ETS84237.1 - 1e-37 129.8 0.0 1.8e-37 129.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS84237.1 - 2.1e-05 24.4 0.1 5.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS84237.1 - 0.00013 21.8 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS84237.1 - 0.00085 18.2 0.1 0.17 10.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A ThiF PF00899.16 ETS84237.1 - 0.0034 17.2 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 ETS84237.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS84237.1 - 0.013 15.2 0.1 0.88 9.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS84237.1 - 0.024 13.6 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 ETS84237.1 - 0.028 13.0 0.2 1.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS84237.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 ETS84238.1 - 1.5e-37 128.9 0.9 2.5e-37 128.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84238.1 - 1.1e-09 38.0 7.4 2.3e-09 37.0 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sas10_Utp3 PF04000.10 ETS84241.1 - 1.4e-16 60.4 0.5 1.4e-16 60.4 0.4 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hus1 PF04005.7 ETS84241.1 - 0.43 9.4 2.6 0.97 8.3 1.8 1.8 1 1 0 1 1 1 0 Hus1-like protein NPV_P10 PF05531.7 ETS84241.1 - 0.46 10.7 2.1 82 3.5 0.1 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Sigma70_ner PF04546.8 ETS84241.1 - 5.3 6.6 20.3 0.94 9.0 11.6 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 ETS84241.1 - 6.1 4.7 11.4 6.7 4.6 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ApbA_C PF08546.6 ETS84242.1 - 3.8e-09 36.6 0.0 6.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 ETS84242.1 - 4.3e-05 22.9 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Alpha-amyl_C PF09071.5 ETS84242.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase, C terminal dsDNA_bind PF01984.15 ETS84243.1 - 6.9e-36 122.5 8.9 8.1e-36 122.2 6.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 ETS84243.1 - 0.011 15.9 0.9 0.015 15.4 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Fes1 PF08609.5 ETS84243.1 - 0.036 14.5 0.6 1.1 9.8 0.0 2.1 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Coq4 PF05019.8 ETS84244.1 - 4.8e-93 310.1 0.0 5.8e-93 309.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF2076 PF09849.4 ETS84245.1 - 1.2e-08 35.2 10.6 1.5e-08 35.0 7.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 ETS84245.1 - 0.0002 21.1 2.6 0.0002 21.1 1.8 1.5 2 0 0 2 2 2 1 CHCH domain GCK PF07802.6 ETS84245.1 - 0.0038 17.3 0.3 0.0061 16.6 0.2 1.4 1 1 0 1 1 1 1 GCK domain UBX PF00789.15 ETS84246.1 - 2.9e-12 46.4 0.0 6.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 ETS84246.1 - 0.00054 19.9 0.1 0.0099 15.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like DUF1423 PF07227.6 ETS84246.1 - 0.063 11.9 11.8 0.097 11.3 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Toprim_C_rpt PF13368.1 ETS84246.1 - 1.5 9.3 5.7 2.5 8.6 2.7 2.4 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat CAF-1_p150 PF11600.3 ETS84246.1 - 2.1 7.6 27.9 3.5 6.9 19.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank_2 PF12796.2 ETS84247.1 - 1.5e-91 300.9 1.8 9.6e-22 77.1 0.5 6.2 3 2 4 7 7 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84247.1 - 2.2e-61 200.7 18.7 1.4e-08 34.1 0.0 10.9 10 2 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 ETS84247.1 - 2.3e-48 161.7 8.9 8.9e-10 38.8 0.1 8.8 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84247.1 - 3.6e-46 154.1 25.1 2.4e-10 40.2 0.1 7.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84247.1 - 5e-43 140.8 8.3 2.1e-06 27.3 0.0 10.3 11 0 0 11 11 10 7 Ankyrin repeat AAA_22 PF13401.1 ETS84247.1 - 9.1e-08 32.3 1.9 4.9e-07 29.9 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 ETS84247.1 - 1.2e-06 28.6 0.1 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETS84247.1 - 1.7e-06 27.7 0.2 4.2e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETS84247.1 - 6.1e-05 23.8 0.0 0.00033 21.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS84247.1 - 0.00039 20.6 0.0 0.00091 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 ETS84247.1 - 0.0065 15.5 0.5 0.0065 15.5 0.3 2.8 2 1 0 3 3 3 1 KAP family P-loop domain MMR_HSR1 PF01926.18 ETS84247.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 ETS84247.1 - 0.031 13.1 0.0 0.074 11.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 ETS84247.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 ETS84247.1 - 0.12 12.5 1.2 0.26 11.4 0.0 2.2 3 0 0 3 3 2 0 RNA helicase DUF3445 PF11927.3 ETS84248.1 - 1.5e-74 250.5 0.2 1.9e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADC PF06314.6 ETS84249.1 - 7.5e-33 113.8 0.0 9e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) ADC PF06314.6 ETS84250.1 - 2.6e-23 82.6 0.0 3.5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans_2 PF11951.3 ETS84251.1 - 2e-23 82.6 1.6 2.7e-23 82.2 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84251.1 - 4.6e-09 36.0 9.4 9.6e-09 35.0 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.7 ETS84252.1 - 1.8e-08 34.1 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 ETS84252.1 - 3.2e-07 29.6 0.1 4.4e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 ETS84252.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS84252.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Cupin KduI PF04962.7 ETS84252.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Aldedh PF00171.17 ETS84253.1 - 9.6e-176 584.6 1.0 1.1e-175 584.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.1 ETS84254.1 - 6.9e-25 87.4 29.9 8.2e-25 87.2 20.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS84254.1 - 1.4e-10 40.1 26.9 1.8e-10 39.7 18.7 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 ETS84255.1 - 1.3e-18 66.8 3.5 2.5e-18 65.9 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS84255.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.3 ETS84256.1 - 1.5e-17 63.2 0.4 2e-17 62.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 ETS84257.1 - 9.4e-19 67.2 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS84257.1 - 7.8e-07 28.8 0.3 1.4e-05 24.7 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS84257.1 - 8.7e-06 26.6 0.0 1.5e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.6 ETS84258.1 - 1.1e-27 96.8 0.0 1.9e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.17 ETS84259.1 - 5.7e-11 41.8 0.0 1.7e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS84259.1 - 2.3e-08 33.9 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 ETS84260.1 - 2.1e-54 183.2 0.0 2.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS84260.1 - 1e-17 64.6 0.0 1.5e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS84260.1 - 6.4e-08 32.0 0.0 7.7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CENP-T PF15511.1 ETS84261.1 - 2.5e-104 349.8 18.8 5.8e-104 348.6 13.1 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 ETS84261.1 - 6.5e-09 35.8 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 ETS84261.1 - 1.1e-05 25.4 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS84261.1 - 2.7e-05 24.1 0.0 7.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 ETS84262.1 - 5.3e-64 215.9 0.8 1.1e-63 214.9 0.0 1.7 2 0 0 2 2 2 1 SURF1 family CFEM PF05730.6 ETS84263.1 - 1.7e-06 27.7 6.1 3.2e-06 26.8 4.2 1.4 1 0 0 1 1 1 1 CFEM domain tRNA-synt_2 PF00152.15 ETS84264.1 - 2.7e-72 243.3 0.1 4e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS84264.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 ETS84264.1 - 3.3 6.3 9.2 4.4 5.9 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CMS1 PF14617.1 ETS84265.1 - 9.3e-90 300.0 2.3 1.1e-89 299.8 1.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 ETS84265.1 - 2.3e-06 27.2 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase 2OG-FeII_Oxy_3 PF13640.1 ETS84266.1 - 0.002 18.6 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fumble PF03630.9 ETS84272.1 - 1.3e-132 441.8 0.6 1.1e-131 438.8 0.4 2.0 1 1 0 1 1 1 1 Fumble RGS PF00615.14 ETS84273.1 - 4e-05 23.7 0.1 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF718 PF05336.8 ETS84273.1 - 0.06 13.1 0.3 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF718) DUF1348 PF07080.6 ETS84274.1 - 5.3e-59 198.1 7.5 6.4e-59 197.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 ETS84274.1 - 1.1e-08 35.4 1.9 1.4e-08 35.0 1.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS84274.1 - 1.6e-05 25.0 0.3 2.2e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 ETS84274.1 - 0.047 13.2 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Methyltransf_2 PF00891.13 ETS84275.1 - 8.8e-07 28.3 0.0 1.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase NIPSNAP PF07978.8 ETS84275.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP Methyltransf_2 PF00891.13 ETS84276.1 - 1.6e-09 37.3 0.0 1.9e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase AAA PF00004.24 ETS84278.1 - 3.4e-31 108.1 0.0 1.5e-30 106.0 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS84278.1 - 1.7e-05 23.9 0.0 3.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 ETS84278.1 - 5.2e-05 24.0 0.2 0.00025 21.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS84278.1 - 6.4e-05 23.0 0.0 0.0002 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 ETS84278.1 - 9e-05 22.3 0.0 0.00025 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS84278.1 - 0.00044 20.3 0.1 0.0063 16.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETS84278.1 - 0.00073 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 ETS84278.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 ETS84278.1 - 0.006 15.3 0.2 0.035 12.8 0.0 2.2 2 1 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 ETS84278.1 - 0.0062 16.2 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 ETS84278.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 ETS84278.1 - 0.019 14.5 0.5 0.072 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS84278.1 - 0.023 15.0 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS84278.1 - 0.033 14.4 0.1 0.21 11.9 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Mg_chelatase PF01078.16 ETS84278.1 - 0.041 13.0 0.4 0.16 11.1 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETS84278.1 - 0.053 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 ETS84278.1 - 0.1 11.9 0.1 0.62 9.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS84278.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 ETS84278.1 - 0.13 11.4 0.8 0.56 9.3 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Clr5 PF14420.1 ETS84279.1 - 3.9e-10 39.4 4.9 3.9e-10 39.4 3.4 2.3 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 ETS84279.1 - 1.5e-07 31.2 15.8 0.044 13.7 0.7 4.9 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 ETS84279.1 - 0.00038 20.1 0.3 0.38 10.7 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS84279.1 - 0.0021 17.6 3.3 0.019 14.7 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS84279.1 - 0.0083 15.7 1.4 1.8 8.3 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS84279.1 - 0.027 15.1 4.1 5.1 8.0 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 ETS84279.1 - 0.053 13.1 1.7 1.6 8.4 0.1 3.4 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.1 ETS84279.1 - 0.42 10.9 3.9 6 7.2 0.4 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS84279.1 - 0.54 10.1 4.6 11 6.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Oxidored_FMN PF00724.15 ETS84280.1 - 1e-39 136.5 0.0 1.4e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DeoC PF01791.4 ETS84280.1 - 0.003 16.8 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase MFS_1 PF07690.11 ETS84281.1 - 1.6e-34 119.2 50.4 4.1e-34 117.8 34.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84281.1 - 4.5e-07 28.8 15.2 4.5e-07 28.8 10.5 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter AMP-binding PF00501.23 ETS84282.1 - 1.9e-53 181.3 0.0 3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 ETS84282.1 - 2.3e-16 59.5 0.7 3.8e-16 58.7 0.5 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 ETS84282.1 - 1.3e-08 34.9 0.1 3.9e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AATase PF07247.7 ETS84282.1 - 0.0017 17.0 0.0 0.0029 16.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase Abhydrolase_3 PF07859.8 ETS84283.1 - 4.6e-24 85.1 0.1 5.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS84283.1 - 2.3e-13 49.5 0.0 3.9e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS84283.1 - 0.00046 19.9 0.1 0.0007 19.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS84283.1 - 0.0081 15.4 0.0 0.7 9.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Zn_clus PF00172.13 ETS84284.1 - 7.4e-08 32.1 8.3 7.4e-08 32.1 5.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 ETS84285.1 - 1e-22 79.9 3.8 1.8e-22 79.1 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS84285.1 - 8.7e-17 60.8 0.0 1.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS84285.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 ETS84286.1 - 4.6e-15 55.8 0.1 8.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS84286.1 - 7.4e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS84286.1 - 1.5e-07 31.7 0.0 7.2e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84286.1 - 9.4e-07 29.4 0.1 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84286.1 - 1.1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 ETS84286.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 ETS84286.1 - 0.025 14.6 0.1 0.047 13.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.3 ETS84286.1 - 0.079 11.8 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 ETS84286.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_19 PF04672.7 ETS84286.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase AMP-binding PF00501.23 ETS84287.1 - 5.2e-94 314.9 0.7 6.2e-94 314.7 0.5 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84287.1 - 2.1e-10 41.4 0.0 6.7e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 ETS84288.1 - 2.3e-80 270.0 0.0 3.4e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 ETS84288.1 - 1.1e-65 221.4 0.0 1.6e-32 112.5 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 ETS84288.1 - 5.1e-26 90.7 1.0 9.5e-12 45.0 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS84288.1 - 0.0067 17.3 0.0 0.029 15.3 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Podoplanin PF05808.6 ETS84289.1 - 0.013 15.0 0.7 0.019 14.5 0.5 1.2 1 0 0 1 1 1 0 Podoplanin TPR_12 PF13424.1 ETS84290.1 - 0.028 14.3 0.0 4.9 7.1 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS84290.1 - 0.046 13.6 0.1 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 ETS84291.1 - 3.2e-24 85.4 0.0 4.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS84291.1 - 0.0026 18.3 0.0 0.0089 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Sigma70_r3 PF04539.11 ETS84291.1 - 0.032 14.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_20 PF12840.2 ETS84291.1 - 0.036 13.8 0.3 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain CheR PF01739.13 ETS84291.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 ETS84291.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.5 ETS84291.1 - 0.14 11.7 0.5 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain F-box-like PF12937.2 ETS84292.1 - 2.4e-05 23.9 0.0 5.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS84292.1 - 0.023 14.3 0.0 0.24 11.1 0.0 2.6 2 1 0 2 2 2 0 F-box domain HET PF06985.6 ETS84293.1 - 3.6e-29 101.7 0.4 6.6e-29 100.8 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CbiN PF02553.10 ETS84293.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Cobalt transport protein component CbiN Ank_2 PF12796.2 ETS84294.1 - 4.4e-55 183.9 19.5 1.1e-17 64.1 0.9 5.8 2 1 4 6 6 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84294.1 - 9.2e-29 97.8 15.2 0.00011 21.7 0.1 11.3 10 1 1 11 11 11 5 Ankyrin repeat Ank_4 PF13637.1 ETS84294.1 - 5.7e-28 96.7 2.1 9.3e-07 29.1 0.0 7.0 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84294.1 - 5.9e-24 83.5 9.1 2.9e-08 33.6 0.4 7.2 3 3 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84294.1 - 2.9e-22 76.5 3.9 0.02 15.1 0.0 11.2 11 0 0 11 11 10 4 Ankyrin repeat NACHT PF05729.7 ETS84294.1 - 1.9e-11 43.9 0.0 4.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 ETS84294.1 - 1.5e-05 25.1 0.0 9.5e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS84294.1 - 2.6e-05 24.3 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS84294.1 - 6.3e-05 23.0 0.3 0.0012 18.8 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 ETS84294.1 - 0.00021 20.7 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS84294.1 - 0.00059 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 ETS84294.1 - 0.0017 19.1 0.0 0.0097 16.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain Abhydrolase_6 PF12697.2 ETS84294.1 - 0.0034 17.2 0.2 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 ETS84294.1 - 0.0079 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_18 PF13238.1 ETS84294.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS84294.1 - 0.026 14.2 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETS84294.1 - 0.031 13.3 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 ETS84294.1 - 0.032 13.2 0.2 7.1 5.5 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DNA_pol3_delta2 PF13177.1 ETS84294.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit LCAT PF02450.10 ETS84294.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AAA_14 PF13173.1 ETS84294.1 - 0.19 11.6 0.1 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Redoxin PF08534.5 ETS84295.1 - 2.5e-35 121.1 0.0 2.7e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 ETS84295.1 - 4.4e-11 42.5 0.0 5.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF295 PF03478.13 ETS84295.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF1772 PF08592.6 ETS84296.1 - 3.9e-21 75.2 0.3 3.9e-21 75.2 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) ThiF PF00899.16 ETS84297.1 - 1.4e-34 118.8 0.0 2.7e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 ETS84297.1 - 0.011 14.7 0.1 0.03 13.2 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 ETS84297.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 ETS84297.1 - 0.069 13.1 3.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 TrkA-N domain MAF_flag10 PF01973.13 ETS84297.1 - 0.082 12.4 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF115 ApbA PF02558.11 ETS84297.1 - 0.093 12.1 0.4 0.19 11.1 0.3 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 ETS84297.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M14 PF00246.19 ETS84298.1 - 2.2e-47 162.0 0.6 2.8e-47 161.6 0.4 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase adh_short_C2 PF13561.1 ETS84299.1 - 2.5e-20 73.2 0.0 2.9e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS84299.1 - 1e-10 41.7 3.0 1.3e-10 41.4 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS84299.1 - 0.0032 16.9 0.2 0.22 10.9 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 ETS84299.1 - 0.0038 16.3 0.1 0.0067 15.5 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.5 ETS84299.1 - 0.0044 16.7 0.5 0.008 15.8 0.4 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS84299.1 - 0.0058 16.3 0.9 0.011 15.5 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 ETS84299.1 - 0.0097 16.1 0.1 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Oxidored_nitro PF00148.14 ETS84299.1 - 0.053 12.1 0.1 0.11 11.1 0.0 1.4 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.1 ETS84299.1 - 0.44 10.5 3.7 0.38 10.7 1.5 1.8 2 1 0 2 2 2 0 NADH(P)-binding NUDIX PF00293.23 ETS84300.1 - 3.1e-05 23.6 0.1 5.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Mito_fiss_reg PF05308.6 ETS84301.1 - 0.013 14.8 0.3 0.013 14.8 0.2 5.2 2 1 2 5 5 5 0 Mitochondrial fission regulator ABC_membrane PF00664.18 ETS84302.1 - 2.2e-78 263.4 49.1 6.8e-42 143.7 13.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS84302.1 - 2.2e-71 238.5 0.0 2.5e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS84302.1 - 3.5e-13 49.3 0.0 0.00027 20.2 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS84302.1 - 6.7e-11 42.6 0.0 0.08 12.8 0.1 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 ETS84302.1 - 1.1e-09 37.7 0.1 0.00035 20.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 ETS84302.1 - 6.4e-09 34.8 1.4 0.0074 14.9 0.3 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 ETS84302.1 - 2.9e-07 30.6 5.9 4.2e-05 23.6 0.2 3.1 2 1 1 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 ETS84302.1 - 6.4e-07 28.6 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS84302.1 - 1.7e-06 27.6 0.2 0.09 12.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 ETS84302.1 - 2.5e-06 27.6 1.5 0.15 12.1 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS84302.1 - 2.1e-05 25.3 0.0 0.23 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS84302.1 - 5.9e-05 22.9 0.0 0.25 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 ETS84302.1 - 0.00016 21.3 3.8 1.5 8.3 0.5 4.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 ETS84302.1 - 0.00074 19.8 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS84302.1 - 0.0015 18.5 0.1 0.24 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 ETS84302.1 - 0.0028 17.3 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS84302.1 - 0.003 17.4 2.4 4.2 7.3 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 ETS84302.1 - 0.0032 16.5 0.4 2.4 7.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.15 ETS84302.1 - 0.0081 14.8 0.0 2.4 6.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_14 PF13173.1 ETS84302.1 - 0.0081 16.0 0.0 13 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 ETS84302.1 - 0.0081 15.1 0.0 1.4 7.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 ETS84302.1 - 0.01 15.5 0.2 20 4.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 ETS84302.1 - 0.011 15.6 0.1 3.2 7.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS84302.1 - 0.021 14.2 0.8 4.8 6.5 0.1 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 ETS84302.1 - 0.031 14.6 0.3 5.6 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 ETS84302.1 - 0.032 13.6 0.2 7.3 5.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 ETS84302.1 - 0.07 12.6 0.7 26 4.1 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 ETS84302.1 - 0.071 12.1 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 ETS84302.1 - 0.097 12.8 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Aldedh PF00171.17 ETS84303.1 - 1.7e-136 455.2 0.0 2.1e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS84303.1 - 0.0012 17.6 0.1 0.0041 15.8 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ADH_zinc_N PF00107.21 ETS84304.1 - 2.5e-27 94.9 0.4 4e-27 94.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS84304.1 - 3.2e-21 75.1 2.6 3.9e-21 74.8 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 ETS84304.1 - 0.052 13.2 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 SIS domain AlaDh_PNT_C PF01262.16 ETS84304.1 - 0.071 12.6 0.4 0.071 12.6 0.3 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 ETS84304.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Esterase_phd PF10503.4 ETS84305.1 - 1.5e-18 66.8 0.2 2.3e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS84305.1 - 6.7e-14 51.6 0.7 9.4e-14 51.1 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 ETS84305.1 - 0.00046 19.0 1.4 0.00058 18.6 0.6 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS84305.1 - 0.0045 16.5 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 ETS84306.1 - 2.3e-65 220.9 0.0 3.1e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 ETS84307.1 - 0.015 14.5 0.0 0.049 12.9 0.0 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PFK PF00365.15 ETS84308.1 - 1.8e-164 545.5 0.4 1.2e-119 398.4 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 ETS84308.1 - 0.017 14.6 1.3 0.046 13.2 0.9 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif CBFD_NFYB_HMF PF00808.18 ETS84309.1 - 4.7e-17 61.7 0.2 4.7e-17 61.7 0.2 2.1 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS84309.1 - 7.6e-06 25.9 0.1 2.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.3 ETS84309.1 - 0.036 14.1 0.1 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Bromo_TP PF07524.8 ETS84309.1 - 0.04 13.6 0.7 0.78 9.5 0.1 2.4 2 1 1 3 3 3 0 Bromodomain associated RuvA_C PF07499.8 ETS84309.1 - 0.059 13.5 0.5 44 4.3 0.0 3.7 4 0 0 4 4 4 0 RuvA, C-terminal domain DUF2145 PF09916.4 ETS84309.1 - 0.06 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) HEAT_PBS PF03130.11 ETS84309.1 - 0.09 13.2 0.0 7.2 7.3 0.0 2.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Flu_M1_C PF08289.6 ETS84309.1 - 0.096 12.7 0.3 0.14 12.2 0.2 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain adh_short PF00106.20 ETS84310.1 - 1.4e-29 103.1 0.7 2e-29 102.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84310.1 - 6.8e-17 62.0 0.1 8.4e-17 61.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84310.1 - 4.6e-14 52.4 0.3 6.5e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS84310.1 - 4.7e-05 23.4 0.2 6.5e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS84310.1 - 0.0057 15.9 0.1 0.061 12.5 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_Gly3P_dh_N PF01210.18 ETS84310.1 - 0.0066 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HEAT_2 PF13646.1 ETS84310.1 - 0.016 15.4 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats Polysacc_synt_2 PF02719.10 ETS84310.1 - 0.022 13.6 0.1 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CoA_binding_2 PF13380.1 ETS84310.1 - 0.042 14.0 0.3 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 CoA binding domain DUF1776 PF08643.5 ETS84310.1 - 0.1 11.7 0.0 1.2 8.2 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DAO PF01266.19 ETS84311.1 - 1.5e-33 116.1 5.6 6.1e-33 114.1 3.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS84311.1 - 0.00068 19.9 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS84311.1 - 0.00071 19.5 0.0 0.52 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84311.1 - 0.004 17.1 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 ETS84311.1 - 0.043 12.7 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_9 PF13454.1 ETS84311.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS84311.1 - 0.1 11.5 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETS84311.1 - 0.11 11.4 0.0 0.91 8.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain COX16 PF14138.1 ETS84313.1 - 1.6e-31 108.3 0.1 1.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.2 ETS84313.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PI3_PI4_kinase PF00454.22 ETS84314.1 - 8.1e-48 162.9 0.0 1.4e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 ETS84314.1 - 6.6e-42 143.7 10.0 6.6e-42 143.7 6.9 1.8 2 0 0 2 2 2 1 FAT domain UME PF08064.8 ETS84314.1 - 2.5e-20 72.4 2.0 1.8e-19 69.6 0.0 3.3 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 ETS84314.1 - 6.1e-16 57.5 0.0 1.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 ETS84314.1 - 0.0014 18.8 0.0 0.78 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS84314.1 - 0.021 15.2 1.0 30 5.3 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS84314.1 - 0.047 14.3 2.4 10 7.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.23 ETS84315.1 - 7.5e-17 61.2 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Adeno_E3B PF03376.9 ETS84316.1 - 2.9 7.8 7.7 7.4 6.5 1.6 3.0 2 0 0 2 2 2 0 Adenovirus E3B protein FAD_binding_4 PF01565.18 ETS84317.1 - 2e-20 72.7 0.1 3.1e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS84317.1 - 0.031 14.1 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like KapB PF08810.5 ETS84317.1 - 0.042 13.8 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Kinase associated protein B FMN_dh PF01070.13 ETS84318.1 - 2.1e-108 362.3 0.0 2.8e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS84318.1 - 2.7e-17 62.3 0.0 5.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS84318.1 - 4.7e-05 22.4 0.0 7.6e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS84318.1 - 0.0043 15.9 2.4 0.0058 15.5 0.7 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS84318.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 ETS84318.1 - 0.072 12.0 0.1 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase HpcH_HpaI PF03328.9 ETS84319.1 - 5.7e-36 123.4 0.0 6.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 ETS84319.1 - 0.05 12.2 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF2567 PF10821.3 ETS84319.1 - 0.11 11.9 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) TauD PF02668.11 ETS84320.1 - 5.9e-46 157.2 0.2 6.8e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 ETS84320.1 - 0.0068 16.8 0.2 6.5 7.3 0.0 2.9 3 1 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily Polyketide_cyc2 PF10604.4 ETS84321.1 - 0.00029 21.0 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2236 PF09995.4 ETS84322.1 - 3.6e-28 98.5 0.3 5.5e-28 97.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF4044 PF13253.1 ETS84322.1 - 0.24 10.5 2.2 0.48 9.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) adh_short PF00106.20 ETS84323.1 - 8.5e-27 94.0 0.2 1.5e-26 93.2 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84323.1 - 1.6e-12 47.4 0.1 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS84323.1 - 4.1e-12 46.4 0.2 5.8e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 ETS84323.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 ETS84323.1 - 0.041 13.3 0.1 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 ETS84324.1 - 2.2e-12 46.4 0.4 4e-12 45.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 ETS84325.1 - 2.1e-13 49.9 0.3 4.7e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Dioxygenase FA_desaturase PF00487.19 ETS84326.1 - 2.6e-25 89.3 18.6 2.6e-25 89.3 12.9 2.0 1 1 1 2 2 2 1 Fatty acid desaturase PrgI PF12666.2 ETS84326.1 - 0.51 10.5 4.6 0.64 10.2 0.7 2.6 3 0 0 3 3 3 0 PrgI family protein Abhydrolase_3 PF07859.8 ETS84327.1 - 5.6e-45 153.5 0.0 9e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS84327.1 - 2.3e-09 36.5 0.2 9.9e-09 34.4 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS84327.1 - 0.00028 20.1 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS84327.1 - 0.00049 20.0 0.0 0.00097 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS84327.1 - 0.0037 17.0 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acyl_transf_1 PF00698.16 ETS84328.1 - 1.9e-65 221.2 2.0 3.1e-65 220.6 1.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 ETS84328.1 - 2.2e-62 210.8 0.1 6.1e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 ETS84328.1 - 4.2e-58 196.0 1.9 5.9e-58 195.4 0.0 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 ETS84328.1 - 8e-58 195.9 0.1 1.6e-57 194.9 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS84328.1 - 1e-44 152.3 0.1 7.3e-44 149.6 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS84328.1 - 4e-34 117.0 0.2 1.3e-33 115.4 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS84328.1 - 2.6e-15 56.1 0.0 6.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 ETS84328.1 - 5.9e-14 52.3 0.0 2.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS84328.1 - 6.2e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84328.1 - 2.5e-10 40.1 0.0 5.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84328.1 - 1.5e-09 38.4 0.0 9.8e-09 35.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS84328.1 - 3e-09 37.8 0.0 1.3e-08 35.7 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 ETS84328.1 - 1.5e-06 28.5 0.0 4.4e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 ETS84328.1 - 2.1e-06 27.4 0.1 6.1e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 ETS84328.1 - 1.2e-05 25.5 0.0 3.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 ETS84328.1 - 4.1e-05 23.8 0.0 0.00018 21.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 ETS84328.1 - 0.0051 16.2 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 ETS84328.1 - 0.05 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 ETS84329.1 - 2.5e-28 98.7 36.0 2.5e-28 98.7 24.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84329.1 - 4.5e-12 45.2 8.5 4.5e-12 45.2 5.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Ribosomal_L21e PF01157.13 ETS84329.1 - 0.24 11.2 0.1 0.43 10.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L21e Peptidase_M3 PF01432.15 ETS84330.1 - 8.5e-114 381.0 0.1 1.1e-113 380.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF3425 PF11905.3 ETS84331.1 - 1.3e-18 67.1 0.5 7.7e-18 64.6 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 ETS84331.1 - 0.0012 18.8 10.1 0.0025 17.7 7.0 1.5 1 1 0 1 1 1 1 bZIP transcription factor RNA_pol_Rpb6 PF01192.17 ETS84331.1 - 0.13 11.9 0.1 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 Pyr_redox_3 PF13738.1 ETS84332.1 - 6.5e-18 65.5 0.0 1.9e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84332.1 - 7.4e-16 57.4 0.2 6.6e-14 50.9 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS84332.1 - 3.9e-09 36.3 0.0 1.4e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84332.1 - 1.3e-08 34.1 0.4 1.6e-06 27.3 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS84332.1 - 0.0084 15.8 0.0 6.4 6.5 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 ETS84332.1 - 0.057 12.3 0.1 1.5 7.6 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 ETS84332.1 - 0.082 11.9 0.3 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 ETS84332.1 - 0.75 9.8 0.0 0.75 9.8 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Aldedh PF00171.17 ETS84333.1 - 9.5e-140 465.9 0.0 1.1e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS84333.1 - 0.005 15.6 0.1 0.028 13.1 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1440 PF07274.7 ETS84334.1 - 0.013 15.5 0.3 0.093 12.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) Abhydrolase_3 PF07859.8 ETS84335.1 - 2e-52 177.8 0.1 2.7e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS84335.1 - 2.5e-14 52.7 0.0 3.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS84335.1 - 2.6e-11 43.4 0.2 3.4e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS84335.1 - 1.3e-10 41.5 2.7 3.5e-10 40.1 1.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS84335.1 - 0.00085 19.6 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.7 ETS84335.1 - 0.0017 18.1 0.0 0.0037 16.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.11 ETS84335.1 - 0.044 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 ETS84335.1 - 0.14 11.3 0.0 0.53 9.4 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 ETS84336.1 - 3e-27 95.2 32.0 4e-27 94.8 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 ETS84336.1 - 7.3 7.0 6.7 0.64 10.4 0.2 2.5 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rep_3 PF01051.16 ETS84337.1 - 0.0022 17.6 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Initiator Replication protein Foamy_virus_ENV PF03408.9 ETS84337.1 - 0.11 9.9 0.1 0.12 9.8 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein DSX_dimer PF08828.5 ETS84337.1 - 0.14 11.6 1.1 0.26 10.8 0.1 1.8 1 1 1 2 2 2 0 Doublesex dimerisation domain GATase PF00117.23 ETS84338.1 - 5.8e-12 45.4 0.1 7.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 ETS84338.1 - 3.6e-07 29.8 0.3 8.2e-07 28.6 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 Fungal_trans PF04082.13 ETS84339.1 - 8.3e-24 83.8 0.9 1.3e-23 83.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1155 PF06633.6 ETS84339.1 - 0.03 13.5 0.1 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) HET PF06985.6 ETS84340.1 - 1.5e-18 67.2 4.5 1.6e-14 54.2 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.9 ETS84341.1 - 0.0053 15.8 2.4 0.0053 15.8 1.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 HET PF06985.6 ETS84342.1 - 4.1e-36 124.1 0.7 4.1e-36 124.1 0.5 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.1 ETS84342.1 - 0.00068 19.2 0.1 0.049 13.4 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS84342.1 - 0.0015 18.3 0.0 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat RepL PF05732.6 ETS84342.1 - 0.0074 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) TPR_14 PF13428.1 ETS84342.1 - 0.031 14.8 0.1 0.78 10.5 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS84342.1 - 0.099 13.3 0.0 0.51 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS84343.1 - 7.5e-22 77.5 28.8 1.2e-21 76.8 19.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FMN_dh PF01070.13 ETS84344.1 - 4.1e-119 397.5 0.1 5e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS84344.1 - 2.2e-07 30.0 0.2 8.3e-06 24.9 0.1 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS84344.1 - 4e-05 22.6 0.1 0.00011 21.2 0.0 1.7 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 ETS84344.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 ETS84344.1 - 0.0065 15.4 0.0 0.72 8.7 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase ThiG PF05690.9 ETS84344.1 - 0.033 13.2 0.1 3.7 6.5 0.0 2.5 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 ETS84344.1 - 0.051 12.8 0.0 0.46 9.7 0.0 2.1 1 1 0 2 2 2 0 Histidine biosynthesis protein Lactamase_B PF00753.22 ETS84345.1 - 1.1e-10 41.5 2.2 2.2e-10 40.4 1.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS84345.1 - 1.3e-06 28.0 0.2 1.8e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS84345.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EpuA PF11772.3 ETS84345.1 - 0.19 11.1 1.9 8 5.9 0.3 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta adh_short PF00106.20 ETS84346.1 - 2.4e-27 95.9 0.8 3e-27 95.5 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84346.1 - 6.5e-19 68.6 0.6 8.8e-19 68.2 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84346.1 - 4.3e-09 36.2 0.2 7.4e-09 35.5 0.0 1.5 1 1 1 2 2 2 1 KR domain Pyr_redox_3 PF13738.1 ETS84347.1 - 3.9e-25 89.0 0.0 8.1e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84347.1 - 2e-10 40.5 0.1 6.3e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 ETS84347.1 - 1.9e-08 32.9 0.0 4.6e-07 28.4 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 ETS84347.1 - 9.8e-08 31.2 3.0 0.00035 19.5 0.2 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS84347.1 - 5.5e-07 28.8 0.0 0.0013 17.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS84347.1 - 7.5e-07 29.2 0.0 2.4e-05 24.2 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS84347.1 - 1.2e-05 24.4 0.0 0.0032 16.4 0.0 3.0 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS84347.1 - 1.3e-05 24.2 0.0 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 ETS84347.1 - 2.3e-05 24.2 0.1 0.025 14.3 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS84347.1 - 0.00076 18.6 1.0 0.0066 15.5 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 ETS84347.1 - 0.0011 17.9 0.0 0.27 10.0 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 ETS84347.1 - 0.0077 16.3 0.3 1.8 8.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 ETS84347.1 - 0.058 12.4 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 ETS84347.1 - 0.063 11.7 1.4 0.19 10.1 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.20 ETS84348.1 - 8.2e-28 97.4 0.8 1.5e-27 96.5 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84348.1 - 2.1e-16 60.4 0.0 2.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84348.1 - 3.6e-13 49.5 2.4 1.5e-12 47.5 1.7 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS84348.1 - 0.01 15.3 0.3 0.018 14.4 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS84348.1 - 0.01 14.7 0.2 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 ETS84348.1 - 0.18 11.6 1.5 0.31 10.8 0.4 1.8 1 1 1 2 2 2 0 ThiF family Dynamin_N PF00350.18 ETS84349.1 - 1e-33 116.5 0.4 2.1e-33 115.5 0.3 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 ETS84349.1 - 8.3e-17 60.8 0.0 1.7e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 ETS84349.1 - 1.5e-06 28.1 0.4 1.6e-05 24.8 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS84349.1 - 0.00038 20.9 0.0 0.00091 19.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 ETS84349.1 - 0.0098 15.8 0.0 0.042 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain 4HB_MCP_1 PF12729.2 ETS84349.1 - 0.051 12.9 0.2 4.2 6.6 0.3 2.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FeoB_N PF02421.13 ETS84349.1 - 0.051 12.8 0.5 11 5.2 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_23 PF13476.1 ETS84349.1 - 1.6 9.0 5.8 0.47 10.7 0.3 2.7 2 1 0 2 2 2 0 AAA domain Cyclase PF04199.8 ETS84351.1 - 6.2e-16 58.5 0.0 9.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase WWE PF02825.15 ETS84351.1 - 0.057 12.8 0.2 0.26 10.7 0.1 2.0 2 0 0 2 2 2 0 WWE domain DUF1935 PF09149.5 ETS84351.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Pyr_redox_3 PF13738.1 ETS84352.1 - 4.3e-19 69.3 0.0 2.1e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84352.1 - 1.3e-15 56.6 0.1 5.3e-15 54.6 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS84352.1 - 1.5e-10 40.9 0.0 5.3e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84352.1 - 7.1e-07 28.4 0.0 0.001 18.0 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS84352.1 - 6.1e-06 26.2 0.0 0.0002 21.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS84352.1 - 1.1e-05 25.2 0.0 0.00053 19.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 ETS84352.1 - 0.0033 16.5 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 ETS84352.1 - 0.007 15.3 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS84352.1 - 0.028 12.8 0.3 0.092 11.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 ETS84352.1 - 0.19 10.5 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 ETS84353.1 - 2.5e-28 99.0 0.0 3.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84353.1 - 2.3e-27 96.2 0.0 2.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84353.1 - 2.7e-07 30.4 0.2 4.5e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS84353.1 - 0.00041 19.1 1.0 0.00061 18.5 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 ETS84353.1 - 0.016 15.2 0.2 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.10 ETS84353.1 - 0.064 12.1 0.1 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 ETS84353.1 - 0.12 11.9 0.9 0.18 11.4 0.6 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS84353.1 - 0.41 10.1 2.4 0.67 9.4 1.7 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 ETS84354.1 - 2e-58 197.4 0.0 2.9e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS84354.1 - 2e-07 30.1 0.0 4.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS84354.1 - 0.0014 17.9 0.0 0.82 8.8 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS84354.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS84354.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Cyclase PF04199.8 ETS84355.1 - 1.4e-14 54.1 0.1 2e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase UDPGT PF00201.13 ETS84356.1 - 3.1e-05 22.7 0.0 4.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SNF2_N PF00176.18 ETS84357.1 - 2.4e-72 243.2 0.2 3.1e-72 242.8 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS84357.1 - 3.4e-12 46.0 0.0 9.1e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS84357.1 - 2.2e-07 30.9 0.0 4.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS84357.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-B_dimeris PF09026.5 ETS84357.1 - 0.032 14.4 4.9 0.11 12.7 3.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_22 PF13401.1 ETS84357.1 - 0.04 14.0 0.2 0.49 10.5 0.0 2.7 2 2 0 2 2 2 0 AAA domain Med17 PF10156.4 ETS84358.1 - 1.3e-84 284.1 0.0 1.9e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex LigB PF02900.13 ETS84359.1 - 1.6e-53 181.4 0.1 1.8e-53 181.3 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_2 PF02230.11 ETS84360.1 - 2.5e-62 210.1 0.0 3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 ETS84360.1 - 1.8e-15 56.9 0.0 3.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS84360.1 - 9.1e-13 48.6 2.0 4.6e-06 26.6 0.7 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS84360.1 - 6.4e-08 32.0 0.3 1.2e-05 24.7 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 ETS84360.1 - 2.8e-07 30.2 0.0 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 ETS84360.1 - 3.5e-06 26.7 0.1 0.078 12.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 ETS84360.1 - 5.5e-05 22.8 0.0 0.3 10.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 ETS84360.1 - 5.7e-05 22.5 0.0 9.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.9 ETS84360.1 - 0.0013 17.9 0.0 0.055 12.6 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase BAAT_C PF08840.6 ETS84360.1 - 0.02 14.6 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 ETS84360.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Esterase_phd PF10503.4 ETS84360.1 - 0.023 13.9 0.1 0.71 9.0 0.0 2.2 1 1 1 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.7 ETS84360.1 - 0.058 11.8 0.1 0.46 8.9 0.0 2.2 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 ETS84360.1 - 0.13 11.6 0.5 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2920 PF11144.3 ETS84360.1 - 0.13 11.2 0.0 4.4 6.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Cutinase PF01083.17 ETS84360.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Esterase PF00756.15 ETS84360.1 - 0.17 11.2 0.2 0.39 10.1 0.1 1.9 1 1 0 1 1 1 0 Putative esterase Ank_2 PF12796.2 ETS84361.1 - 1e-40 137.9 8.5 4.1e-12 46.2 0.5 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84361.1 - 2.1e-33 112.4 19.6 1.8e-06 27.4 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 ETS84361.1 - 6.5e-27 90.9 5.0 0.0018 18.3 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 ETS84361.1 - 7.8e-24 83.1 10.7 2.2e-05 24.5 0.0 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS84361.1 - 7.7e-22 77.2 8.1 1.5e-05 25.3 0.2 5.1 4 2 1 5 5 5 4 Ankyrin repeats (many copies) WD40 PF00400.27 ETS84362.1 - 2.2e-23 81.1 15.2 3e-09 36.4 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 ETS84362.1 - 0.00038 18.8 2.7 0.14 10.3 0.1 3.7 4 0 0 4 4 4 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 ETS84362.1 - 0.034 13.9 0.0 2 8.1 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 ETS84362.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SecE PF00584.15 ETS84363.1 - 8.7e-12 44.4 0.0 1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 ETS84364.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS84364.1 - 0.00098 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SnoaL_2 PF12680.2 ETS84365.1 - 0.003 17.9 0.1 0.0056 17.0 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain DUF2815 PF10991.3 ETS84365.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Abhydrolase_1 PF00561.15 ETS84366.1 - 9.4e-27 94.0 0.0 3.1e-26 92.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS84366.1 - 2.6e-22 79.8 0.1 3.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS84366.1 - 4.1e-12 46.0 0.0 2e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS84366.1 - 9.3e-05 21.7 0.0 0.032 13.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 ETS84366.1 - 0.068 11.6 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.11 ETS84366.1 - 0.068 12.5 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 ETS84366.1 - 0.074 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S28 PF05577.7 ETS84366.1 - 0.086 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Fib_alpha PF08702.5 ETS84367.1 - 0.004 17.2 8.0 0.0058 16.7 5.6 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Sigma70_ner PF04546.8 ETS84367.1 - 0.0099 15.5 12.3 0.015 14.9 8.5 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region ERCC4 PF02732.10 ETS84367.1 - 0.01 15.5 0.8 0.012 15.3 0.6 1.2 1 0 0 1 1 1 0 ERCC4 domain RHH_1 PF01402.16 ETS84367.1 - 0.013 15.3 0.9 0.069 13.0 0.1 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF1798 PF08807.5 ETS84367.1 - 0.019 14.6 2.2 0.03 14.0 1.5 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Merozoite_SPAM PF07133.6 ETS84367.1 - 0.022 14.6 13.5 0.029 14.2 9.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3263 PF11662.3 ETS84367.1 - 0.025 14.0 1.2 0.043 13.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) AAA_13 PF13166.1 ETS84367.1 - 0.041 12.3 8.6 0.043 12.2 6.0 1.1 1 0 0 1 1 1 0 AAA domain Tho2 PF11262.3 ETS84367.1 - 1.7 7.6 7.3 2.7 6.9 5.1 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1664 PF07889.7 ETS84367.1 - 2.2 8.1 9.9 0.97 9.2 1.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 ETS84367.1 - 2.6 6.8 11.4 3.5 6.4 7.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IQ-like PF15157.1 ETS84368.1 - 0.0031 17.6 0.4 0.17 12.0 0.1 2.3 2 0 0 2 2 2 1 IQ-like IncA PF04156.9 ETS84368.1 - 0.0068 16.0 10.1 0.014 14.9 7.0 1.6 1 1 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 ETS84368.1 - 0.017 14.9 6.1 0.017 14.9 4.2 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DMPK_coil PF08826.5 ETS84368.1 - 0.038 13.8 0.9 0.038 13.8 0.6 2.2 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF1735 PF08522.5 ETS84368.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Microtub_assoc PF07989.6 ETS84368.1 - 0.094 12.5 0.4 0.094 12.5 0.2 2.7 2 1 1 3 3 3 0 Microtubule associated DivIC PF04977.10 ETS84368.1 - 0.1 12.1 3.5 0.51 9.8 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 ETS84368.1 - 0.21 11.3 13.1 0.031 14.1 4.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2229 PF09989.4 ETS84368.1 - 0.65 9.4 3.1 0.49 9.8 0.6 1.8 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DivIVA PF05103.8 ETS84368.1 - 0.75 9.8 7.3 1.8 8.6 5.1 1.7 1 1 0 1 1 1 0 DivIVA protein DUF1127 PF06568.6 ETS84368.1 - 0.86 9.0 3.6 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Seryl_tRNA_N PF02403.17 ETS84368.1 - 2.9 7.9 9.8 0.16 11.9 1.0 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 ETS84368.1 - 8.9 5.2 13.5 17 4.3 9.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 TMCO5 PF14992.1 ETS84368.1 - 9.5 5.2 13.9 11 5.0 6.0 2.2 1 1 1 2 2 2 0 TMCO5 family Sel1 PF08238.7 ETS84369.1 - 1.6e-41 139.7 23.8 1.2e-05 25.7 0.0 7.9 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.1 ETS84369.1 - 0.022 14.9 0.1 1 9.6 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 ETS84369.1 - 0.15 12.1 1.3 0.35 11.0 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS84369.1 - 0.2 12.3 0.2 0.2 12.3 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.2 ETS84370.1 - 5.3e-71 235.0 19.7 1e-18 67.4 0.1 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84370.1 - 3.8e-50 165.2 15.5 1.8e-08 33.8 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 ETS84370.1 - 7.7e-38 124.7 7.5 0.00021 21.2 0.0 9.6 10 0 0 10 10 9 7 Ankyrin repeat Ank_4 PF13637.1 ETS84370.1 - 2.9e-35 120.0 7.1 1.7e-09 37.9 0.1 7.0 6 1 1 7 7 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84370.1 - 4.5e-31 106.1 11.9 3e-07 30.4 0.1 8.7 2 2 6 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 ETS84370.1 - 1.1e-14 54.3 0.0 2.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 ETS84370.1 - 2.6e-13 49.4 0.0 6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 ETS84370.1 - 1.3e-05 25.2 0.2 0.00011 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 ETS84370.1 - 0.00065 19.5 0.0 0.003 17.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS84370.1 - 0.0016 18.3 0.0 0.026 14.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS84370.1 - 0.0038 17.4 0.0 0.024 14.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 ETS84370.1 - 0.0057 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 ETS84370.1 - 0.01 14.7 0.1 0.048 12.5 0.0 2.2 2 1 1 3 3 3 0 NB-ARC domain AAA_22 PF13401.1 ETS84370.1 - 0.014 15.5 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS84370.1 - 0.015 15.4 0.2 0.039 14.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase RTA1 PF04479.8 ETS84372.1 - 1.7e-44 151.9 5.7 2.3e-44 151.5 4.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2207 PF09972.4 ETS84372.1 - 1.9 6.9 4.7 4.1 5.8 2.5 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Fungal_trans_2 PF11951.3 ETS84373.1 - 3.5e-47 160.8 5.6 3.5e-47 160.8 3.9 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Toxin_37 PF11415.3 ETS84373.1 - 0.074 12.6 0.2 0.31 10.6 0.1 2.1 1 0 0 1 1 1 0 Antifungal peptide termicin Zn_clus PF00172.13 ETS84373.1 - 0.087 12.7 1.0 0.19 11.6 0.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 ETS84374.1 - 5.9e-129 430.3 0.5 2.3e-128 428.4 0.4 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS84374.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3445 PF11927.3 ETS84375.1 - 6.2e-73 245.2 0.0 7e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) AMP-binding PF00501.23 ETS84376.1 - 5.2e-46 156.8 0.0 7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84376.1 - 0.00033 21.5 0.1 0.0012 19.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 ETS84377.1 - 9e-40 136.8 0.0 1.3e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 ETS84377.1 - 6e-06 25.5 0.0 1.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 ETS84377.1 - 7.3e-06 25.9 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84377.1 - 8.7e-06 24.8 0.1 0.0032 16.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS84377.1 - 0.0001 21.3 1.6 0.00078 18.4 0.1 2.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS84377.1 - 0.00023 21.5 0.2 0.035 14.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS84377.1 - 0.00047 18.7 0.1 0.00088 17.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS84377.1 - 0.0015 17.5 0.2 0.0045 15.9 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS84377.1 - 0.0018 17.2 0.1 0.0036 16.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS84377.1 - 0.0019 18.2 0.1 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS84377.1 - 0.0021 18.0 1.0 0.042 13.8 0.1 2.8 3 0 0 3 3 3 1 TrkA-N domain Pyr_redox_2 PF07992.9 ETS84377.1 - 0.0042 16.9 0.1 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 ETS84377.1 - 0.018 13.2 0.1 1.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 ETS84377.1 - 0.054 13.2 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 ETS84377.1 - 0.15 11.1 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 ETS84377.1 - 0.17 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.13 ETS84378.1 - 0.0011 17.9 0.4 0.0023 16.8 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 ETS84379.1 - 1.9e-36 125.5 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 ETS84380.1 - 2.5e-10 40.4 3.6 7.3e-10 38.9 1.3 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS84380.1 - 9.3e-05 22.9 1.6 0.0013 19.3 0.1 2.4 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 ETS84380.1 - 0.0008 19.3 0.2 0.0018 18.2 0.2 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.17 ETS84381.1 - 2.1e-68 230.9 0.0 2.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_71 PF03659.9 ETS84382.1 - 1.6e-151 504.2 7.9 2.4e-151 503.6 5.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Herpes_gE PF02480.11 ETS84385.1 - 0.0039 15.5 0.0 0.0048 15.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E V-set PF07686.12 ETS84385.1 - 0.033 14.0 1.1 0.077 12.8 0.8 1.6 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF2207 PF09972.4 ETS84385.1 - 0.054 12.0 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.6 ETS84385.1 - 0.057 12.9 0.1 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Podoplanin SSP160 PF06933.6 ETS84385.1 - 0.06 11.3 7.0 0.081 10.9 4.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 VPEP PF07589.6 ETS84385.1 - 0.74 9.7 6.8 0.49 10.3 3.1 2.0 1 1 0 1 1 1 0 PEP-CTERM motif SKG6 PF08693.5 ETS84385.1 - 1.1 8.5 10.6 0.07 12.4 3.4 2.1 2 1 0 2 2 2 0 Transmembrane alpha-helix domain p450 PF00067.17 ETS84386.1 - 1.3e-44 152.5 0.0 1.6e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 ETS84387.1 - 7.7e-69 227.6 18.6 8.9e-14 51.1 0.2 5.8 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETS84387.1 - 2e-57 189.5 0.9 1.4e-07 31.1 0.2 8.3 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 ETS84387.1 - 1.2e-13 51.3 0.3 0.03 14.9 0.0 5.2 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETS84387.1 - 1.5e-12 46.4 4.6 0.13 12.2 0.1 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS84387.1 - 2.4e-11 43.1 0.0 0.0064 16.1 0.0 4.4 3 2 2 5 5 5 4 TPR repeat Clr5 PF14420.1 ETS84387.1 - 2.4e-11 43.3 0.0 5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_4 PF07721.9 ETS84387.1 - 4.8e-11 41.9 6.5 0.47 11.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS84387.1 - 1e-10 41.2 4.0 0.99 10.2 0.0 7.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS84387.1 - 2.2e-09 36.4 2.6 0.13 11.9 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS84387.1 - 5.2e-09 35.2 0.0 0.53 10.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS84387.1 - 6.3e-09 36.0 0.0 0.1 12.9 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS84387.1 - 2.4e-08 33.8 8.5 0.15 12.5 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS84387.1 - 3.3e-08 33.5 2.4 0.024 14.7 0.3 4.3 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 ETS84387.1 - 9.4e-07 28.1 7.1 0.42 10.5 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 ETS84387.1 - 0.0014 18.7 1.5 41 4.3 0.0 5.2 2 1 3 5 5 5 0 Tetratricopeptide repeat CBP4 PF07960.6 ETS84388.1 - 1.3e-35 121.7 0.4 1.6e-35 121.5 0.2 1.1 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 ETS84388.1 - 0.013 15.4 0.6 0.026 14.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Pkip-1 PF06878.6 ETS84388.1 - 0.044 13.6 0.4 0.055 13.3 0.3 1.1 1 0 0 1 1 1 0 Pkip-1 protein SET PF00856.23 ETS84389.1 - 4.3e-18 66.1 0.0 6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Sugar_tr PF00083.19 ETS84390.1 - 5.4e-107 358.1 25.7 1.2e-106 357.0 17.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84390.1 - 4.7e-22 78.1 57.0 1.7e-13 49.9 16.7 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily TPR_16 PF13432.1 ETS84390.1 - 0.062 13.9 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Gate PF07670.9 ETS84390.1 - 0.12 12.3 6.5 0.066 13.1 2.1 2.3 2 0 0 2 2 2 0 Nucleoside recognition TPR_19 PF14559.1 ETS84390.1 - 0.14 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_2 PF13347.1 ETS84390.1 - 0.17 10.2 40.5 0.011 14.1 5.7 3.6 2 2 0 3 3 3 0 MFS/sugar transport protein HEAT_2 PF13646.1 ETS84391.1 - 0.0013 19.0 0.2 0.029 14.6 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats ABC_tran PF00005.22 ETS84392.1 - 1.5e-48 164.5 0.0 1.8e-25 89.8 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 ETS84392.1 - 2.6e-14 53.8 4.8 2e-05 24.7 0.2 3.8 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 ETS84392.1 - 2.7e-13 49.6 0.0 7.1e-05 22.1 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS84392.1 - 1.3e-08 35.3 2.2 0.00013 22.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS84392.1 - 2.7e-07 29.9 0.0 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS84392.1 - 3.7e-07 29.5 0.7 0.021 14.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 ETS84392.1 - 6.5e-07 28.7 0.0 0.5 9.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 ETS84392.1 - 8.5e-07 29.1 0.2 0.18 11.9 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS84392.1 - 1e-06 29.5 1.2 0.017 15.8 0.1 3.4 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 ETS84392.1 - 1.4e-06 28.8 0.0 0.0031 17.9 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 ETS84392.1 - 1.7e-06 27.9 0.0 0.016 15.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS84392.1 - 1.9e-06 27.5 0.8 0.24 10.8 0.1 3.9 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 ETS84392.1 - 5.3e-06 26.2 0.0 0.14 12.0 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 ETS84392.1 - 9.2e-05 22.3 0.0 0.19 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 ETS84392.1 - 0.00012 21.8 0.0 0.13 11.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 ETS84392.1 - 0.00022 20.9 0.1 0.42 10.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 ETS84392.1 - 0.00039 20.2 0.0 0.023 14.5 0.0 3.0 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.12 ETS84392.1 - 0.00039 20.3 1.1 1.1 9.0 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 ETS84392.1 - 0.0012 19.0 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 ETS84392.1 - 0.0014 18.6 0.0 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 ETS84392.1 - 0.0022 16.8 0.4 0.7 8.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA PF00004.24 ETS84392.1 - 0.0038 17.4 0.1 4 7.6 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 ETS84392.1 - 0.0042 16.5 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 ETS84392.1 - 0.0051 16.2 0.0 2.9 7.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 ETS84392.1 - 0.0064 16.0 0.3 6.2 6.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 ETS84392.1 - 0.0084 16.4 0.1 0.94 9.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Chromo PF00385.19 ETS84392.1 - 0.014 15.0 1.2 0.034 13.7 0.8 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Arch_ATPase PF01637.13 ETS84392.1 - 0.02 14.5 0.0 5.7 6.5 0.0 2.9 3 0 0 3 3 2 0 Archaeal ATPase DUF815 PF05673.8 ETS84392.1 - 0.023 13.6 0.0 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.1 ETS84392.1 - 0.026 13.0 0.0 4.2 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 ETS84392.1 - 0.028 13.4 0.0 3.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 ETS84392.1 - 0.031 14.1 0.0 5.3 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 ETS84392.1 - 0.05 12.8 0.5 1.3 8.2 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.14 ETS84392.1 - 0.067 12.6 0.1 14 5.1 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 ETS84392.1 - 0.099 12.3 0.3 22 4.7 0.0 2.8 3 0 0 3 3 2 0 NTPase ATP-synt_ab PF00006.20 ETS84392.1 - 0.12 11.8 0.1 6.3 6.2 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 ETS84392.1 - 0.81 9.6 4.7 3 7.7 0.1 3.4 3 1 0 3 3 3 0 AAA ATPase domain HEAT_2 PF13646.1 ETS84392.1 - 1.9 8.8 6.0 2.3 8.5 0.1 3.7 2 1 2 4 4 3 0 HEAT repeats Fungal_trans_2 PF11951.3 ETS84393.1 - 3e-05 22.8 0.0 5.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM219A PF15260.1 ETS84393.1 - 0.018 15.3 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein family FAM219A MFS_1 PF07690.11 ETS84395.1 - 1.7e-34 119.0 15.6 2.5e-34 118.5 10.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84395.1 - 1.1e-09 37.4 4.5 1.1e-09 37.4 3.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS84395.1 - 1.1e-05 24.0 15.2 0.00011 20.7 0.8 3.8 1 1 3 4 4 4 3 MFS/sugar transport protein MFS_3 PF05977.8 ETS84395.1 - 0.00017 19.8 1.6 0.00017 19.8 1.1 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 ETS84395.1 - 0.028 12.6 1.6 0.044 11.9 1.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) TMEM238 PF15125.1 ETS84395.1 - 0.052 13.4 3.2 7.6 6.5 0.2 3.2 3 0 0 3 3 3 0 TMEM238 protein family DoxD PF04173.8 ETS84395.1 - 0.055 13.1 1.4 0.13 11.9 1.0 1.5 1 0 0 1 1 1 0 TQO small subunit DoxD Neuromodulin_N PF10580.4 ETS84395.1 - 5.2 6.7 5.4 9.6 5.9 3.7 1.3 1 0 0 1 1 1 0 Gap junction protein N-terminal region DUF3237 PF11578.3 ETS84396.1 - 3.7e-18 65.2 0.0 4.9e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CAF-1_p150 PF11600.3 ETS84397.1 - 0.0074 15.6 2.1 0.0074 15.6 1.4 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dmrt1 PF12374.3 ETS84397.1 - 0.11 12.8 10.4 0.056 13.7 3.6 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 ATP-synt_B PF00430.13 ETS84397.1 - 0.61 9.8 8.7 0.88 9.3 6.0 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Nop53 PF07767.6 ETS84397.1 - 3.4 6.5 11.1 4.7 6.0 7.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.11 ETS84398.1 - 1.2e-26 93.3 36.9 1.2e-26 93.3 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FTA2 PF13095.1 ETS84399.1 - 3.5e-25 88.8 0.0 2.2e-24 86.2 0.0 1.9 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 ETS84399.1 - 0.0063 15.6 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Adeno_E3_CR1 PF02440.10 ETS84400.1 - 0.082 12.4 0.1 0.47 9.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 PA14_2 PF10528.4 ETS84401.1 - 8.2e-22 77.3 4.4 8.2e-22 77.3 3.0 2.7 3 1 1 4 4 4 1 GLEYA domain Transp_cyt_pur PF02133.10 ETS84402.1 - 1.6e-92 310.3 36.9 2.1e-92 309.9 25.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 ETS84402.1 - 2.5e-24 85.5 0.9 4.7e-24 84.6 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84402.1 - 0.0037 17.1 8.2 0.0073 16.2 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF917 PF06032.7 ETS84403.1 - 1.1e-117 392.5 0.0 2.8e-117 391.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 ETS84403.1 - 1.6e-45 155.4 11.3 4.1e-44 150.8 4.4 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS84403.1 - 5.5e-30 104.1 0.8 5.5e-26 91.1 0.0 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 ETS84403.1 - 0.00025 20.4 10.4 0.038 13.2 0.4 2.6 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 ETS84403.1 - 0.0017 16.7 8.3 0.16 10.2 0.5 2.8 2 1 1 3 3 3 2 MutL protein StbA PF06406.6 ETS84403.1 - 0.0037 16.2 0.6 0.84 8.5 0.0 2.6 2 1 0 2 2 2 2 StbA protein FtsA PF14450.1 ETS84403.1 - 0.0068 16.2 1.1 0.57 10.0 0.0 3.2 3 1 0 3 3 3 1 Cell division protein FtsA CM_1 PF07736.6 ETS84403.1 - 0.12 12.4 0.0 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Chorismate mutase type I DUF2786 PF10979.3 ETS84404.1 - 1.1e-08 34.6 0.7 1.1e-08 34.6 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) MCC-bdg_PDZ PF10506.4 ETS84404.1 - 1.5 8.6 6.9 0.35 10.7 1.6 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3328 PF11807.3 ETS84405.1 - 7.8e-18 64.9 0.9 1e-17 64.5 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cutinase PF01083.17 ETS84406.1 - 1.9e-35 122.2 9.1 4.4e-35 121.0 6.3 1.6 1 1 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 ETS84406.1 - 1e-05 25.1 0.3 1.5e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 ETS84406.1 - 6.5e-05 22.5 1.0 0.00028 20.5 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84406.1 - 0.0034 17.1 0.8 0.0062 16.2 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS84406.1 - 0.0062 16.4 0.0 0.008 16.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 ETS84406.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.6 ETS84406.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 ETS84406.1 - 0.024 14.0 0.1 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 ETS84406.1 - 0.045 13.3 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Tyrosinase PF00264.15 ETS84408.1 - 8.6e-32 111.0 5.9 1.2e-31 110.6 4.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 ETS84409.1 - 6e-20 72.3 3.9 9.2e-20 71.7 2.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.23 ETS84410.1 - 7.9e-34 117.2 0.1 8.9e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family 3-PAP PF12578.3 ETS84410.1 - 0.05 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-associated protein COesterase PF00135.23 ETS84411.1 - 7.1e-56 190.0 0.0 8.2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family M16C_assoc PF08367.6 ETS84412.1 - 0.04 12.7 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated COesterase PF00135.23 ETS84413.1 - 4.1e-110 368.9 0.0 5.4e-110 368.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS84413.1 - 7.4e-05 22.4 0.2 0.0033 17.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Cortex-I_coil PF09304.5 ETS84414.1 - 0.0047 16.9 1.3 0.0047 16.9 0.9 3.9 1 1 3 4 4 4 1 Cortexillin I, coiled coil DUF3095 PF11294.3 ETS84414.1 - 0.24 10.4 8.7 0.38 9.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) DUF3568 PF12092.3 ETS84414.1 - 0.79 9.4 5.0 1.7 8.3 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) IncA PF04156.9 ETS84414.1 - 1.4 8.5 40.0 0.041 13.4 2.8 3.1 1 1 2 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 ETS84414.1 - 1.5 8.7 41.5 3.6 7.4 3.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 ETS84414.1 - 2.8 7.7 37.6 1.4 8.7 9.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.1 ETS84414.1 - 3.9 6.6 41.7 0.12 11.5 8.6 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF603 PF04645.7 ETS84414.1 - 4 7.3 15.0 4.7 7.1 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF603 RTBV_P46 PF06216.6 ETS84414.1 - 6 5.5 16.8 5.4 5.7 2.7 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein PhoU PF01895.14 ETS84414.1 - 8.4 6.9 9.8 2.5 8.6 1.3 3.2 2 1 0 3 3 3 0 PhoU domain BING4CT PF08149.6 ETS84414.1 - 8.7 5.9 7.3 0.35 10.4 0.4 2.2 3 0 0 3 3 3 0 BING4CT (NUC141) domain Lumazine_bd PF12870.2 ETS84415.1 - 0.0078 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Lumazine-binding domain Leu_zip PF15294.1 ETS84415.1 - 0.0098 15.0 4.4 0.014 14.5 3.0 1.1 1 0 0 1 1 1 1 Leucine zipper FH2 PF02181.18 ETS84415.1 - 0.019 13.8 1.1 0.028 13.3 0.7 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Spc7 PF08317.6 ETS84415.1 - 0.02 13.5 2.2 0.026 13.2 1.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3367 PF11847.3 ETS84415.1 - 0.035 12.0 0.7 0.046 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) USP8_interact PF08941.5 ETS84415.1 - 0.057 12.7 0.9 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 USP8 interacting Atg14 PF10186.4 ETS84415.1 - 0.12 11.2 2.7 0.2 10.5 1.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 ETS84415.1 - 0.24 9.2 1.3 0.28 9.0 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLTH PF10607.4 ETS84415.1 - 1.9 8.1 4.6 3.3 7.3 3.2 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Arylesterase PF01731.15 ETS84416.1 - 2.8e-05 24.0 0.2 0.00016 21.6 0.1 2.1 2 0 0 2 2 2 1 Arylesterase DUF1730 PF08331.5 ETS84416.1 - 0.14 11.7 0.2 0.34 10.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) p450 PF00067.17 ETS84417.1 - 2.6e-58 197.6 0.0 4.8e-58 196.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 ETS84419.1 - 1.2e-19 69.8 0.6 1.2e-19 69.8 0.4 2.7 2 1 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.10 ETS84420.1 - 3.5e-08 33.1 0.0 4.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS84420.1 - 1.2e-05 25.3 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FAD_binding_3 PF01494.14 ETS84422.1 - 1.7e-21 76.6 0.0 1.5e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS84422.1 - 0.0001 21.3 0.5 0.017 14.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS84422.1 - 0.00046 20.1 0.4 0.0041 17.1 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS84422.1 - 0.0007 18.6 0.2 0.19 10.6 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 ETS84422.1 - 0.0027 18.0 0.5 0.006 16.9 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS84422.1 - 0.0058 15.7 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 ETS84422.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS84422.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS84422.1 - 0.026 14.1 0.1 0.065 12.7 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 ETS84422.1 - 0.059 12.1 0.4 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3425 PF11905.3 ETS84423.1 - 4.1e-25 88.2 0.0 7.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FMO-like PF00743.14 ETS84424.1 - 6.6e-15 54.2 0.8 1.7e-12 46.3 0.6 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS84424.1 - 1.4e-14 54.6 0.0 4.8e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84424.1 - 1.3e-09 37.9 0.0 6.4e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS84424.1 - 1.4e-05 24.2 0.1 0.00038 19.5 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS84424.1 - 0.027 14.2 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS84424.1 - 0.05 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 ETS84424.1 - 0.076 13.1 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_2 PF00797.12 ETS84425.1 - 9e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase RRM_5 PF13893.1 ETS84426.1 - 5.3e-10 38.9 0.0 9.6e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS84426.1 - 1.3e-09 37.5 0.0 2.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS84426.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS84426.1 - 0.0066 16.2 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ETS84426.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif AMP-binding PF00501.23 ETS84427.1 - 5.5e-79 265.4 0.0 6.8e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84427.1 - 7.8e-13 49.1 0.0 3.7e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 ETS84428.1 - 3.9e-30 104.7 34.0 3.9e-30 104.7 23.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.6 ETS84429.1 - 3.2e-20 72.6 5.2 1.9e-18 66.9 3.6 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_3 PF13302.1 ETS84430.1 - 6.4e-17 62.0 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS84430.1 - 2.7e-05 24.1 0.0 5.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS84430.1 - 3.8e-05 23.6 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS84430.1 - 5.7e-05 23.1 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FAA_hydrolase PF01557.13 ETS84431.1 - 6.6e-59 198.9 0.0 8.1e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Lactonase PF10282.4 ETS84432.1 - 2.8e-69 233.8 0.3 4.9e-69 233.0 0.1 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.11 ETS84433.1 - 6.7e-21 74.3 55.5 6.7e-21 74.3 38.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 ETS84433.1 - 1.1e-05 24.1 29.4 0.00016 20.2 20.4 2.2 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Aldolase_II PF00596.16 ETS84434.1 - 8.8e-47 159.0 0.6 1.1e-46 158.7 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PhyH PF05721.8 ETS84435.1 - 1.9e-05 24.7 0.1 3.2e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1932 PF09130.6 ETS84436.1 - 1.6e-14 53.4 0.1 4.1e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 ETS84436.1 - 2.5e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS84436.1 - 4.4e-05 23.8 0.1 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 ETS84436.1 - 0.0023 17.1 0.0 0.004 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS84436.1 - 0.055 13.1 0.1 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cu-oxidase PF00394.17 ETS84437.1 - 1.3e-21 77.2 0.1 3.3e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS84437.1 - 9.1e-20 70.5 13.2 4e-18 65.2 3.8 4.1 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS84437.1 - 7.3e-19 67.6 4.7 1.5e-17 63.4 0.4 3.2 2 1 0 2 2 2 1 Multicopper oxidase Methyltransf_6 PF03737.10 ETS84438.1 - 1.6e-16 60.5 0.1 2.6e-16 59.8 0.1 1.3 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Antimicrobial_5 PF08026.6 ETS84438.1 - 0.13 12.1 0.3 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Bee antimicrobial peptide Sugar_tr PF00083.19 ETS84439.1 - 5.3e-98 328.5 19.6 6e-98 328.3 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84439.1 - 1.7e-27 96.0 20.4 1.7e-27 96.0 14.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily TPR_9 PF13371.1 ETS84439.1 - 0.09 12.6 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DIOX_N PF14226.1 ETS84440.1 - 3.6e-20 72.6 0.0 6.1e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS84440.1 - 1.1e-16 60.9 0.0 1.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS84441.1 - 9.3e-46 156.1 34.8 1.1e-45 155.8 24.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84441.1 - 6.6e-10 38.1 18.5 1.3e-09 37.2 12.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS84441.1 - 6.3e-05 21.3 4.8 0.00011 20.5 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 ETS84441.1 - 0.0093 14.0 14.7 3.9 5.3 10.0 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fig1 PF12351.3 ETS84441.1 - 0.02 14.7 2.7 0.44 10.4 0.4 2.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Tyrosinase PF00264.15 ETS84442.1 - 9.7e-43 146.8 1.8 1.3e-42 146.5 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.13 ETS84443.1 - 9.4e-10 37.7 0.2 1.7e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS84445.1 - 2.4e-07 30.7 0.2 3.2e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETS84445.1 - 1.2e-06 27.9 1.1 2.2e-06 27.1 0.8 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS84445.1 - 0.00015 21.8 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS84445.1 - 0.00041 20.0 0.2 0.00065 19.4 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS84445.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.19 ETS84445.1 - 0.017 15.4 0.2 0.06 13.6 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 ETS84445.1 - 0.089 12.2 0.1 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 ETS84446.1 - 1.7e-08 33.4 1.4 2.6e-08 32.9 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 ETS84447.1 - 1.3e-45 155.7 0.0 1.7e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS84448.1 - 2.3e-44 151.5 35.5 2.3e-44 151.5 24.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84448.1 - 1.1e-06 27.5 30.1 3.5e-06 25.8 20.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 ETS84448.1 - 3.3e-05 22.2 0.4 6.4e-05 21.2 0.3 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector CbtA PF09490.5 ETS84448.1 - 0.019 14.2 1.2 0.019 14.2 0.8 3.1 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtA) Zn_clus PF00172.13 ETS84449.1 - 1.6e-08 34.3 5.2 3.5e-08 33.2 3.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID_90kDa PF04494.10 ETS84449.1 - 0.0063 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit MFS_1 PF07690.11 ETS84450.1 - 1.4e-26 93.0 24.1 1.4e-26 93.0 16.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84450.1 - 1.5e-07 30.3 12.6 1.5e-07 30.3 8.7 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter DAO PF01266.19 ETS84451.1 - 1.6e-45 155.6 1.7 1.9e-45 155.3 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS84451.1 - 3.8e-06 26.8 0.5 1.1e-05 25.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS84451.1 - 2.3e-05 24.2 0.0 0.0012 18.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS84451.1 - 0.00011 22.1 0.2 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS84451.1 - 0.00018 21.6 0.0 0.8 9.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS84451.1 - 0.00026 20.1 1.8 0.0012 17.9 0.2 2.2 1 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 ETS84451.1 - 0.0075 15.1 1.4 0.018 13.8 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 ETS84451.1 - 0.008 16.5 0.3 0.029 14.7 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS84451.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Strep_67kDa_ant PF06100.6 ETS84451.1 - 0.069 11.4 0.0 0.088 11.1 0.0 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family COesterase PF00135.23 ETS84452.1 - 8e-71 239.3 0.0 1e-70 238.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS84452.1 - 1e-05 25.2 0.9 7.7e-05 22.3 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS84452.1 - 0.00088 18.7 0.1 0.0057 16.1 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 ETS84452.1 - 0.0026 17.0 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS84452.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_7 PF13508.1 ETS84453.1 - 8.3e-12 45.1 0.1 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS84453.1 - 3.2e-10 39.9 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS84453.1 - 0.0006 19.6 0.1 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS84453.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain DUF3237 PF11578.3 ETS84454.1 - 3.8e-23 81.4 0.0 4.5e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Methyltransf_11 PF08241.7 ETS84455.1 - 4.6e-14 52.6 0.1 8.2e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84455.1 - 5.1e-13 48.8 0.1 1.8e-11 43.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS84455.1 - 2.4e-10 40.6 0.1 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS84455.1 - 1e-09 37.8 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS84455.1 - 3.5e-09 37.0 0.1 1.5e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS84455.1 - 2.4e-08 33.8 0.0 4.3e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84455.1 - 8.3e-08 32.8 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS84455.1 - 6e-05 23.0 0.2 0.00017 21.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS84455.1 - 0.00026 20.6 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS84455.1 - 0.041 13.2 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 ETS84455.1 - 0.06 13.3 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase AAA_12 PF13087.1 ETS84456.1 - 1.5e-33 115.8 0.0 3.2e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS84456.1 - 3e-26 92.4 1.0 7.2e-14 51.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS84456.1 - 6.5e-09 35.4 0.4 3.6e-07 29.8 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS84456.1 - 1.3e-07 31.3 0.0 2.6e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS84456.1 - 0.0038 16.6 0.0 0.009 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 ETS84456.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein GMC_oxred_N PF00732.14 ETS84457.1 - 5.2e-26 91.4 0.0 8.7e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS84457.1 - 7.9e-19 68.3 0.5 1.7e-18 67.2 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 ETS84457.1 - 2.2e-07 31.1 0.1 0.0066 16.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS84457.1 - 1.7e-05 23.8 1.9 5.8e-05 22.1 1.3 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS84457.1 - 2.6e-05 24.1 0.5 0.0052 16.6 0.1 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS84457.1 - 0.00019 20.4 4.6 0.00048 19.1 0.3 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS84457.1 - 0.00024 19.6 0.9 0.00083 17.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 ETS84457.1 - 0.00034 20.5 0.2 0.0015 18.5 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 ETS84457.1 - 0.00043 19.4 0.8 0.00069 18.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 ETS84457.1 - 0.0022 17.1 0.2 0.0063 15.6 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 ETS84457.1 - 0.0035 16.3 0.1 0.0067 15.3 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 ETS84457.1 - 0.069 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPR_12 PF13424.1 ETS84458.1 - 2.3e-72 238.9 34.4 2.5e-17 62.5 0.2 5.3 2 1 5 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 ETS84458.1 - 4.3e-49 163.1 18.7 8.8e-11 41.3 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat HET PF06985.6 ETS84458.1 - 2.4e-20 73.0 6.9 5.2e-17 62.3 4.8 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 ETS84458.1 - 1.1e-14 53.8 5.9 4.6e-06 26.1 0.2 4.7 1 1 4 5 5 5 5 TPR repeat NB-ARC PF00931.17 ETS84458.1 - 9.5e-13 47.6 0.0 1.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 ETS84458.1 - 4.7e-12 44.9 4.1 0.24 11.0 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS84458.1 - 1.5e-10 40.0 17.5 0.2 11.5 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS84458.1 - 3.8e-10 39.1 0.9 4.7 7.6 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS84458.1 - 8.9e-10 38.5 0.1 0.011 15.8 0.0 4.4 2 1 2 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS84458.1 - 1.6e-08 35.0 5.9 0.0045 17.6 0.5 4.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS84458.1 - 5.8e-08 32.0 17.2 0.77 9.8 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS84458.1 - 5.1e-07 29.5 6.8 0.31 11.5 0.4 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.1 ETS84458.1 - 3e-06 27.3 0.1 2.5e-05 24.3 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS84458.1 - 0.00019 21.5 0.0 0.0012 18.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 ETS84458.1 - 0.00025 21.2 11.2 5.2 7.4 0.2 5.9 4 2 4 8 8 7 2 Tetratricopeptide repeat Coatomer_E PF04733.9 ETS84458.1 - 0.00026 20.2 1.2 0.48 9.5 0.0 3.3 1 1 2 3 3 3 2 Coatomer epsilon subunit NACHT PF05729.7 ETS84458.1 - 0.00066 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 ETS84458.1 - 0.0029 18.1 21.3 11 7.0 0.0 8.1 5 3 3 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS84458.1 - 0.0031 17.1 5.7 5.7 6.9 0.1 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF3366 PF11846.3 ETS84458.1 - 0.0084 16.0 1.9 4.6 7.0 0.0 4.2 5 0 0 5 5 4 1 Domain of unknown function (DUF3366) PPR PF01535.15 ETS84458.1 - 0.014 15.3 4.6 56 4.0 0.0 5.5 6 0 0 6 6 5 0 PPR repeat TPR_6 PF13174.1 ETS84458.1 - 0.021 15.2 7.2 1.2e+02 3.5 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 ETS84458.1 - 0.16 12.3 2.6 15 6.1 0.0 4.6 5 0 0 5 5 4 0 Pentatricopeptide repeat domain Fig1 PF12351.3 ETS84462.1 - 5.8e-11 42.6 1.1 1e-10 41.8 0.0 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 ABC2_membrane PF01061.19 ETS84462.1 - 0.055 12.6 8.4 0.081 12.0 3.1 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Glyco_hydro_17 PF00332.13 ETS84464.1 - 1.6e-09 37.2 0.1 1.1e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3169 PF11368.3 ETS84464.1 - 0.17 11.0 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PTPLA PF04387.9 ETS84466.1 - 3.6e-43 146.8 0.1 7.3e-43 145.8 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA FAD_binding_4 PF01565.18 ETS84467.1 - 5.7e-26 90.6 1.2 8.7e-26 90.0 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_11 PF00457.12 ETS84467.1 - 0.0048 16.2 0.4 0.0088 15.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Lactamase_B PF00753.22 ETS84468.1 - 9.6e-12 44.9 0.4 2.3e-11 43.7 0.3 1.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS84468.1 - 0.0083 15.6 0.1 0.024 14.1 0.0 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain ORC6 PF05460.8 ETS84469.1 - 0.1 11.7 0.4 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NAP PF00956.13 ETS84470.1 - 3.1e-37 127.9 0.1 4.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Scytalone_dh PF02982.9 ETS84473.1 - 4.1e-91 302.7 0.4 4.8e-91 302.5 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 ETS84473.1 - 2e-08 34.2 0.4 3.2e-08 33.5 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain PHF5 PF03660.9 ETS84475.1 - 0.011 15.7 5.7 0.042 13.9 1.7 2.3 2 0 0 2 2 2 0 PHF5-like protein peroxidase PF00141.18 ETS84475.1 - 0.042 13.3 0.4 0.085 12.3 0.2 1.7 1 1 0 1 1 1 0 Peroxidase DZR PF12773.2 ETS84475.1 - 0.28 11.0 10.5 2.1 8.2 4.6 2.9 2 1 1 3 3 3 0 Double zinc ribbon DUF968 PF06147.6 ETS84475.1 - 0.42 10.4 2.3 4.4 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF968) DUF2039 PF10217.4 ETS84475.1 - 2.4 8.2 12.0 24 5.0 6.3 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) NUDIX PF00293.23 ETS84476.1 - 4.9e-15 55.3 0.0 9.9e-14 51.1 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain YjzC PF14168.1 ETS84476.1 - 0.12 12.2 0.4 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 YjzC-like protein DUF2231 PF09990.4 ETS84477.1 - 0.15 12.4 0.3 0.15 12.4 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) SHP PF03579.8 ETS84477.1 - 0.98 8.8 7.7 1.8 7.9 0.1 3.4 3 0 0 3 3 3 0 Small hydrophobic protein Peptidase_S8 PF00082.17 ETS84479.1 - 1.6e-16 60.2 0.0 2.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family NACHT PF05729.7 ETS84480.1 - 8.3e-14 51.5 0.0 5.9e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.17 ETS84480.1 - 1.2e-13 50.5 0.0 1.2e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 ETS84480.1 - 1.5e-12 47.7 0.0 1.5e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS84480.1 - 2e-12 47.4 0.4 6.2e-06 26.3 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 ETS84480.1 - 1.2e-08 35.7 0.1 0.0036 18.1 0.0 4.0 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 ETS84480.1 - 1.1e-07 31.5 0.0 0.00073 18.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA PF00004.24 ETS84480.1 - 1.8e-07 31.4 0.0 0.0022 18.2 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS84480.1 - 8.9e-07 28.5 0.4 0.015 15.0 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 ETS84480.1 - 1.8e-05 25.0 0.0 0.052 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS84480.1 - 4.3e-05 22.9 0.0 0.35 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 ETS84480.1 - 4.8e-05 23.0 0.0 0.31 10.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) PhoH PF02562.11 ETS84480.1 - 6.1e-05 22.3 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.1 ETS84480.1 - 6.2e-05 22.9 0.0 0.12 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 ETS84480.1 - 6.8e-05 23.1 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MobB PF03205.9 ETS84480.1 - 8.4e-05 22.3 0.0 0.084 12.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 ETS84480.1 - 0.00011 21.9 0.0 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 ETS84480.1 - 0.00037 20.0 0.0 0.079 12.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 ETS84480.1 - 0.00048 19.9 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase AAA_24 PF13479.1 ETS84480.1 - 0.00052 19.6 0.2 0.98 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 ETS84480.1 - 0.00067 19.7 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 ETS84480.1 - 0.00096 18.3 0.0 0.84 8.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 ETS84480.1 - 0.0012 18.8 0.1 0.68 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 ETS84480.1 - 0.0029 16.6 0.0 0.052 12.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 ETS84480.1 - 0.003 17.4 0.0 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 ETS84480.1 - 0.0043 17.1 0.0 0.46 10.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 ETS84480.1 - 0.0043 16.5 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 ETS84480.1 - 0.0047 15.8 0.0 0.049 12.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 ETS84480.1 - 0.0048 16.7 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 ETS84480.1 - 0.0061 16.2 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.7 ETS84480.1 - 0.0067 15.5 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DZR PF12773.2 ETS84480.1 - 0.0079 15.9 0.5 0.0079 15.9 0.3 3.0 3 1 0 3 3 2 1 Double zinc ribbon AAA_29 PF13555.1 ETS84480.1 - 0.0092 15.4 0.2 1.1 8.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 ETS84480.1 - 0.014 14.5 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 ETS84480.1 - 0.017 14.6 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 ETS84480.1 - 0.018 14.1 0.0 0.097 11.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 ETS84480.1 - 0.04 13.3 0.0 9.8 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Guanylate_kin PF00625.16 ETS84480.1 - 0.052 12.9 0.1 3 7.2 0.0 2.8 3 0 0 3 3 2 0 Guanylate kinase KaiC PF06745.8 ETS84480.1 - 0.099 11.7 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC SRPRB PF09439.5 ETS84480.1 - 0.1 11.8 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.4 ETS84480.1 - 0.14 10.7 0.1 9.8 4.6 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain WIYLD PF10440.4 ETS84480.1 - 0.22 11.4 0.1 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain TIP49 PF06068.8 ETS84480.1 - 0.26 9.9 0.0 2 7.0 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus His_Phos_1 PF00300.17 ETS84481.1 - 1.5e-15 57.6 0.0 3.9e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 ETS84482.1 - 2.4e-26 92.3 66.4 5.7e-16 58.1 21.7 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS84483.1 - 3.7e-23 81.7 0.2 5.9e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.12 ETS84484.1 - 1.2e-29 102.9 0.2 1.5e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NUDIX PF00293.23 ETS84486.1 - 3.2e-11 43.0 0.0 8.6e-10 38.3 0.0 2.6 1 1 0 1 1 1 1 NUDIX domain F-box-like_2 PF13013.1 ETS84486.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Slx4 PF09494.5 ETS84487.1 - 2.1e-22 78.6 0.0 4.4e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.14 ETS84487.1 - 9.4 6.2 29.8 0.031 13.9 1.5 4.4 4 0 0 4 4 4 0 AT hook motif Ribosomal_S21e PF01249.13 ETS84488.1 - 1.1e-41 140.7 0.1 1.2e-41 140.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.9 ETS84489.1 - 1.6e-99 332.5 0.9 2.9e-99 331.7 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 ETS84489.1 - 1.4e-40 138.7 0.0 2.3e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 ETS84489.1 - 0.003 17.7 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family AT_hook PF02178.14 ETS84489.1 - 4.2 7.3 15.0 5.2 7.0 2.7 2.7 2 0 0 2 2 2 0 AT hook motif OPT PF03169.10 ETS84490.1 - 9e-148 493.4 48.4 1e-130 437.1 30.7 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 ETS84490.1 - 1.6 7.6 4.9 0.16 11.0 0.1 1.7 2 0 0 2 2 2 0 E1-E2 ATPase DUF4176 PF13780.1 ETS84491.1 - 0.013 15.2 0.1 0.061 13.0 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3176 PF11374.3 ETS84492.1 - 1.6e-30 105.2 0.3 3.5e-30 104.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) HET PF06985.6 ETS84493.1 - 0.00098 19.2 6.7 0.078 13.1 0.0 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) HAD_2 PF13419.1 ETS84494.1 - 4.2e-18 66.1 0.0 1.1e-17 64.7 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS84494.1 - 1.3e-07 32.2 0.0 1.1e-06 29.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sulfotransfer_1 PF00685.22 ETS84494.1 - 0.0067 15.7 0.0 0.15 11.3 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase domain HAD PF12710.2 ETS84494.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS84494.1 - 0.051 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3176 PF11374.3 ETS84495.1 - 3e-35 120.4 1.0 9e-35 118.9 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) TPR_12 PF13424.1 ETS84496.1 - 2.8e-22 78.4 18.5 6e-08 32.5 0.2 6.2 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 ETS84496.1 - 3.2e-18 65.0 14.6 6.4e-06 25.9 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat NB-ARC PF00931.17 ETS84496.1 - 3.5e-14 52.3 0.0 7e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 ETS84496.1 - 1.2e-10 40.8 8.4 0.026 14.1 0.1 4.9 3 1 2 5 5 5 4 TPR repeat TPR_14 PF13428.1 ETS84496.1 - 5.5e-10 38.9 10.7 2.8 8.8 0.0 7.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS84496.1 - 1.7e-08 34.6 13.2 0.043 14.1 1.0 7.2 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS84496.1 - 2e-08 34.6 0.8 0.021 15.4 0.2 5.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS84496.1 - 4.2e-07 29.9 11.9 0.94 10.0 0.0 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS84496.1 - 9.7e-06 25.0 5.9 5.4 7.0 0.0 7.0 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS84496.1 - 9.7e-06 25.1 7.9 2.5 8.2 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_22 PF13401.1 ETS84496.1 - 4.8e-05 23.5 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 ETS84496.1 - 0.00011 21.6 6.8 2 8.1 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 ETS84496.1 - 0.00018 20.5 0.0 0.0031 16.5 0.0 2.3 2 0 0 2 2 2 1 Phosphorylase superfamily TPR_20 PF14561.1 ETS84496.1 - 0.00042 20.3 8.1 6.2 7.0 0.0 6.7 6 1 2 8 8 7 1 Tetratricopeptide repeat AAA_16 PF13191.1 ETS84496.1 - 0.00067 19.6 4.5 0.00093 19.2 0.4 3.1 2 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.1 ETS84496.1 - 0.00085 18.9 1.6 3.2 7.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS84496.1 - 0.052 13.7 6.6 11 6.5 0.1 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat KaiC PF06745.8 ETS84496.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC TPR_4 PF07721.9 ETS84496.1 - 0.97 10.0 8.2 3.4 8.3 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Vps39_1 PF10366.4 ETS84496.1 - 1.5 8.9 7.7 8.6 6.4 0.1 4.6 4 2 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 Peptidase_M20 PF01546.23 ETS84497.1 - 8.3e-28 97.1 0.0 1.5e-27 96.3 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 ETS84497.1 - 0.0042 16.8 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 ETS84497.1 - 0.08 12.6 0.0 0.38 10.5 0.0 2.2 1 1 0 1 1 1 0 Peptidase dimerisation domain Transp_cyt_pur PF02133.10 ETS84498.1 - 2.7e-25 88.8 30.6 5.3e-25 87.8 21.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.14 ETS84499.1 - 2.9e-64 217.3 0.0 3.5e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS84499.1 - 7.2e-07 28.4 0.0 2.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS84499.1 - 1.4e-05 24.2 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 ETS84499.1 - 1.8e-05 24.6 0.1 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.7 ETS84499.1 - 1.9e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 ETS84499.1 - 4e-05 23.6 0.4 0.0011 18.9 0.3 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS84499.1 - 7.8e-05 21.6 0.0 0.0003 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 ETS84499.1 - 0.00022 19.9 0.0 0.00047 18.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 ETS84499.1 - 0.00029 19.8 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS84499.1 - 0.00041 18.9 0.0 0.00074 18.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETS84499.1 - 0.00072 19.9 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS84499.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 ETS84499.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 ETS84499.1 - 0.015 14.4 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS84499.1 - 0.044 13.6 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 ETS84499.1 - 0.12 12.4 0.1 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 ETS84499.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A CGI-121 PF08617.5 ETS84501.1 - 5.1e-52 175.7 0.1 5.8e-52 175.5 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 PIF1 PF05970.9 ETS84502.1 - 6.9e-42 143.6 0.0 2.8e-27 95.6 0.0 2.8 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 ETS84502.1 - 4.3e-16 59.0 0.0 2.7e-14 53.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Cauli_VI PF01693.11 ETS84502.1 - 1.3e-10 41.0 0.1 2.8e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Herpes_Helicase PF02689.9 ETS84502.1 - 2.5e-06 25.5 0.1 2.9e-05 22.0 0.0 2.2 2 1 1 3 3 3 1 Helicase Viral_helicase1 PF01443.13 ETS84502.1 - 1.1e-05 25.0 1.9 0.11 12.0 0.2 3.6 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS84502.1 - 4.6e-05 23.0 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 ETS84502.1 - 5.8e-05 23.3 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 ETS84502.1 - 6.1e-05 22.6 0.0 0.47 9.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS84502.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 ETS84502.1 - 0.00025 20.5 0.1 0.015 14.7 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS84502.1 - 0.0003 20.9 0.0 0.00085 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 ETS84502.1 - 0.00064 19.8 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.4 ETS84502.1 - 0.0025 16.5 0.0 0.0075 14.9 0.0 1.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 ETS84502.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS84502.1 - 0.0059 16.5 0.0 0.02 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETS84502.1 - 0.0061 15.5 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ArgK PF03308.11 ETS84502.1 - 0.016 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Helicase_RecD PF05127.9 ETS84502.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Helicase T2SE PF00437.15 ETS84502.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 ETS84502.1 - 0.023 13.9 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF258 PF03193.11 ETS84502.1 - 0.024 13.8 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 ETS84502.1 - 0.025 14.8 0.3 0.32 11.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DZR PF12773.2 ETS84502.1 - 0.029 14.1 2.1 0.082 12.7 1.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 ETS84502.1 - 0.04 14.1 0.4 0.15 12.3 0.2 2.1 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain AAA_32 PF13654.1 ETS84502.1 - 0.066 11.8 0.1 0.57 8.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 ETS84502.1 - 0.14 11.8 0.1 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 NTPase zf-C3HC4 PF00097.20 ETS84502.1 - 0.17 11.5 2.3 0.44 10.2 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sigma54_activat PF00158.21 ETS84502.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FAD_binding_4 PF01565.18 ETS84503.1 - 5.1e-22 77.8 1.0 2.9e-21 75.3 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS84503.1 - 7.3e-11 41.8 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 ETS84504.1 - 1.1e-14 54.7 0.9 1.1e-14 54.7 0.6 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 ETS84504.1 - 2.4e-08 33.4 0.0 8.1e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase BNR_2 PF13088.1 ETS84505.1 - 2.8e-07 30.1 0.4 0.0027 17.0 0.1 2.4 2 1 0 2 2 2 2 BNR repeat-like domain AAA PF00004.24 ETS84506.1 - 3.4e-18 66.0 0.0 9.7e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS84506.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS84506.1 - 0.0037 18.0 1.0 0.02 15.6 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS84506.1 - 0.011 15.7 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 ETS84506.1 - 0.016 15.3 0.1 0.087 12.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS84506.1 - 0.054 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 ETS84506.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Varsurf_PPLC PF03490.8 ETS84508.1 - 7.5e-08 31.9 0.0 1.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C p450 PF00067.17 ETS84510.1 - 1.6e-40 139.0 0.0 2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS84511.1 - 2.8e-19 69.6 6.3 2.7e-16 59.9 0.2 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ALIX_LYPXL_bnd PF13949.1 ETS84512.1 - 0.02 13.8 0.7 0.029 13.3 0.5 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV HTH_41 PF14502.1 ETS84512.1 - 0.03 13.9 0.0 0.085 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain OmpH PF03938.9 ETS84512.1 - 0.034 14.0 0.2 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1515 PF07439.6 ETS84512.1 - 0.041 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TPR_7 PF13176.1 ETS84512.1 - 0.11 12.3 0.7 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.15 ETS84513.1 - 8e-13 47.1 0.1 1.1e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 ETS84513.1 - 1.8e-05 23.5 0.0 0.0016 17.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Pro_dh PF01619.13 ETS84515.1 - 1.7e-31 109.3 0.0 2.9e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase AAA_24 PF13479.1 ETS84515.1 - 0.067 12.7 0.1 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Tim17 PF02466.14 ETS84516.1 - 1.6 8.7 8.1 8.1 6.5 5.6 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF3276 PF11680.3 ETS84518.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) PB1 PF00564.19 ETS84518.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Metallophos PF00149.23 ETS84519.1 - 1e-08 34.8 4.8 1e-08 34.8 3.3 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 ETS84521.1 - 4.8e-114 381.4 25.3 5.5e-114 381.2 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84521.1 - 4.5e-21 74.9 56.5 1.9e-18 66.3 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 ETS84522.1 - 2e-34 119.4 0.1 2.9e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS84522.1 - 6.1e-32 110.8 0.2 9.4e-32 110.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84522.1 - 6.9e-13 48.6 0.2 1.9e-12 47.2 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS84522.1 - 1.5e-08 34.3 0.1 8.7e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ETS84522.1 - 3.8e-05 22.9 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS84522.1 - 0.00017 21.6 1.3 0.00068 19.6 0.9 2.0 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS84522.1 - 0.0005 19.8 0.3 0.0012 18.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ETS84522.1 - 0.0025 16.7 0.1 0.0053 15.6 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 ETS84522.1 - 0.012 15.2 1.5 0.071 12.7 0.3 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF2493 PF10686.4 ETS84522.1 - 0.014 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Shikimate_DH PF01488.15 ETS84522.1 - 0.026 14.6 0.2 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 ETS84522.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS84522.1 - 0.061 12.4 0.9 0.084 11.9 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_43 PF04616.9 ETS84523.1 - 8e-38 130.1 6.8 9.7e-38 129.8 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 ETS84524.1 - 3.7e-76 256.4 8.4 5.6e-76 255.8 5.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 ETS84524.1 - 0.12 12.8 0.6 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 C terminal CAP PF00188.21 ETS84525.1 - 1.7e-18 67.2 3.7 2.6e-18 66.6 2.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.11 ETS84526.1 - 1.9e-36 125.5 54.7 1.4e-35 122.7 37.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HBT_2 PF13279.1 ETS84527.1 - 5.7e-08 33.2 0.0 9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily RGS PF00615.14 ETS84528.1 - 0.092 12.8 0.0 0.96 9.5 0.0 2.3 1 1 0 1 1 1 0 Regulator of G protein signaling domain AMP-binding PF00501.23 ETS84529.1 - 0 1123.5 0.0 3e-90 302.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 ETS84529.1 - 1.1e-152 507.0 0.0 9.1e-46 156.0 0.0 5.6 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.20 ETS84529.1 - 3.1e-39 133.0 7.0 1.2e-08 35.1 0.6 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS84529.1 - 1e-18 68.0 0.1 0.00022 22.0 0.0 4.8 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain Vasohibin PF14822.1 ETS84529.1 - 0.53 9.3 0.0 3.1 6.7 0.0 2.2 3 0 0 3 3 3 0 Vasohibin Acyl_transf_1 PF00698.16 ETS84530.1 - 4.3e-60 203.7 0.6 1.5e-58 198.6 0.0 2.5 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 ETS84530.1 - 4.6e-30 103.5 0.0 9.8e-30 102.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 ETS84530.1 - 1.1e-27 95.5 0.1 3e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) NMO PF03060.10 ETS84530.1 - 0.0024 17.0 1.2 0.14 11.3 0.0 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase Ank_2 PF12796.2 ETS84531.1 - 2.3e-13 50.3 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS84531.1 - 4.7e-13 48.9 0.2 7.7e-07 29.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS84531.1 - 6.8e-13 47.7 0.1 6.2e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETS84531.1 - 8.2e-13 48.4 0.1 3.5e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84531.1 - 8.2e-11 41.0 0.0 6.5e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat bZIP_1 PF00170.16 ETS84531.1 - 0.0061 16.4 6.9 0.013 15.4 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor Nop25 PF09805.4 ETS84531.1 - 0.034 14.2 3.8 0.054 13.5 2.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3573 PF12097.3 ETS84531.1 - 0.058 12.0 0.1 0.11 11.0 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) PA26 PF04636.8 ETS84531.1 - 0.27 9.8 0.8 0.38 9.3 0.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF853 PF05872.7 ETS84531.1 - 0.49 8.6 2.1 0.68 8.2 1.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RTA1 PF04479.8 ETS84532.1 - 2.8e-26 92.3 0.4 3.6e-26 92.0 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein OAD_gamma PF04277.8 ETS84532.1 - 0.18 12.1 1.1 1.4 9.3 0.2 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Aminotran_4 PF01063.14 ETS84533.1 - 5.6e-17 61.9 0.0 7.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 ETS84534.1 - 1.1e-59 202.2 0.0 1.4e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 ETS84535.1 - 8e-25 87.7 0.8 7.5e-24 84.5 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 ETS84535.1 - 9.6e-16 58.2 0.0 1.6e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 ETS84535.1 - 1.7e-12 47.2 0.0 4.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_2 PF00891.13 ETS84536.1 - 5.4e-28 97.8 0.0 8.9e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase HTH_45 PF14947.1 ETS84536.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Amidase PF01425.16 ETS84538.1 - 6.3e-69 232.9 0.0 8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3140 PF11338.3 ETS84539.1 - 0.097 12.7 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF1993 PF09351.5 ETS84540.1 - 2e-45 154.6 0.0 2.2e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) GST_N_2 PF13409.1 ETS84541.1 - 3.6e-23 81.3 0.0 1.3e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS84541.1 - 4.8e-15 55.2 0.1 1.2e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS84541.1 - 5.7e-08 32.6 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS84541.1 - 3.8e-05 24.0 0.1 0.00011 22.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS84541.1 - 0.0011 19.1 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Pkinase PF00069.20 ETS84544.1 - 9.3e-37 126.5 0.0 1.3e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS84544.1 - 2.7e-18 65.9 0.0 7.6e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS84544.1 - 0.00018 20.6 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS84544.1 - 0.0092 15.7 0.1 0.03 14.0 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS84544.1 - 0.074 12.6 0.4 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1943 PF09172.6 ETS84544.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Aldolase_II PF00596.16 ETS84546.1 - 3.1e-26 92.1 0.6 4.1e-26 91.7 0.4 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.2 ETS84547.1 - 7.2e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS84547.1 - 0.00013 21.4 0.0 0.00039 19.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain NolV PF06635.7 ETS84547.1 - 0.037 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV Polysacc_deac_1 PF01522.16 ETS84548.1 - 1.3e-11 44.2 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.17 ETS84549.1 - 1.1e-75 254.9 0.0 1.4e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HpcH_HpaI PF03328.9 ETS84550.1 - 2.7e-31 108.2 0.0 3.4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.13 ETS84551.1 - 4e-18 65.2 0.1 9.6e-18 63.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 ETS84552.1 - 2.5e-107 359.1 41.3 3.1e-107 358.8 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS84552.1 - 6.2e-34 117.2 41.6 7.6e-34 116.9 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.13 ETS84553.1 - 1.1e-29 103.2 0.0 1.7e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase zf-LITAF-like PF10601.4 ETS84554.1 - 0.14 12.0 0.3 0.14 12.0 0.2 3.3 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Ank_2 PF12796.2 ETS84555.1 - 2e-70 233.1 24.4 4.5e-14 52.5 0.6 10.1 3 2 8 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS84555.1 - 2.1e-42 142.7 16.3 4.7e-09 36.5 0.2 11.5 9 1 3 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84555.1 - 7.2e-41 137.2 19.2 3.3e-09 36.6 0.1 12.6 8 2 6 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.25 ETS84555.1 - 2.9e-38 127.7 24.3 0.0012 18.5 0.0 15.1 16 1 0 16 16 16 10 Ankyrin repeat Ank_3 PF13606.1 ETS84555.1 - 2e-36 120.3 16.6 0.037 14.2 0.0 16.0 18 0 0 18 18 18 8 Ankyrin repeat NACHT PF05729.7 ETS84555.1 - 6.8e-08 32.3 0.0 2.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS84555.1 - 9.3e-06 25.8 0.0 0.00098 19.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS84555.1 - 0.0001 22.3 0.0 0.0041 17.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS84555.1 - 0.027 14.1 0.0 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase Ank_2 PF12796.2 ETS84557.1 - 1.1e-20 73.7 0.5 4.4e-15 55.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84557.1 - 4.2e-14 51.5 0.3 0.00054 19.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 ETS84557.1 - 1.4e-11 44.1 2.3 0.016 15.4 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84557.1 - 1.6e-10 40.1 0.6 0.0016 18.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS84557.1 - 6.9e-07 29.6 0.4 0.0011 19.4 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 ETS84557.1 - 3.9e-06 26.6 0.2 2.9e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS84557.1 - 0.0023 18.0 0.1 0.0084 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain TBPIP PF07106.8 ETS84557.1 - 0.074 12.5 1.2 0.2 11.1 0.8 1.7 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HET PF06985.6 ETS84558.1 - 1.8e-29 102.7 1.6 3.5e-29 101.7 1.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 ETS84559.1 - 1.7e-12 47.5 0.0 3.8e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS84559.1 - 6.5e-08 32.4 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS84559.1 - 0.0032 17.2 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS84559.1 - 0.046 13.1 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 ETS84560.1 - 1.5e-36 125.8 6.5 2e-36 125.4 4.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1324 PF07038.6 ETS84560.1 - 0.1 12.6 0.4 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1324) Fructosamin_kin PF03881.9 ETS84561.1 - 3.3e-36 124.7 0.0 4e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS84561.1 - 2.2e-06 27.5 0.0 3.9e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS84561.1 - 0.00049 19.3 0.0 0.00077 18.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2252 PF10009.4 ETS84561.1 - 0.089 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF221 PF02714.10 ETS84561.1 - 0.15 10.8 0.4 0.21 10.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 NmrA PF05368.8 ETS84563.1 - 7.8e-33 113.6 0.0 6.2e-32 110.7 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS84563.1 - 5.2e-09 36.3 0.2 8e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 ETS84563.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.20 ETS84563.1 - 0.00086 19.2 0.3 0.0015 18.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 ETS84563.1 - 0.035 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 ETS84563.1 - 0.067 12.1 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Epimerase PF01370.16 ETS84563.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GRIP PF01465.15 ETS84564.1 - 3.2e-13 48.9 0.0 6.9e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Myosin_tail_1 PF01576.14 ETS84564.1 - 1.2e-07 29.9 158.6 0.0008 17.2 29.3 4.2 3 1 1 4 4 4 3 Myosin tail GAS PF13851.1 ETS84564.1 - 2.2e-07 30.2 148.3 0.0021 17.3 8.8 9.0 3 2 6 9 9 9 4 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 ETS84564.1 - 1.3e-06 28.2 168.0 0.00043 20.1 18.1 9.3 3 2 4 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETS84564.1 - 1.2e-05 24.9 159.8 0.067 12.7 8.9 8.6 3 3 4 8 8 8 6 IncA protein Cast PF10174.4 ETS84564.1 - 7.5e-05 21.0 96.8 7.5e-05 21.0 67.1 4.6 1 1 3 4 4 4 3 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.1 ETS84564.1 - 0.00018 20.1 121.7 0.0012 17.3 15.6 5.7 3 2 2 5 5 5 3 AAA domain DUF4200 PF13863.1 ETS84564.1 - 0.0014 18.5 20.8 0.0014 18.5 14.4 10.8 4 3 4 9 9 9 1 Domain of unknown function (DUF4200) DUF745 PF05335.8 ETS84564.1 - 0.0044 16.5 11.5 0.0044 16.5 8.0 8.7 3 2 7 10 10 7 2 Protein of unknown function (DUF745) Filament PF00038.16 ETS84564.1 - 0.005 16.3 138.2 0.091 12.2 31.0 8.6 3 2 4 8 8 8 5 Intermediate filament protein Fib_alpha PF08702.5 ETS84564.1 - 0.0061 16.6 89.5 0.083 13.0 0.3 8.0 3 1 4 7 7 7 4 Fibrinogen alpha/beta chain family FliJ PF02050.11 ETS84564.1 - 0.0092 16.0 13.9 0.0092 16.0 9.6 10.3 5 3 7 12 12 12 2 Flagellar FliJ protein Reo_sigmaC PF04582.7 ETS84564.1 - 0.012 14.7 63.7 0.024 13.8 2.7 6.9 3 2 5 8 8 8 0 Reovirus sigma C capsid protein WEMBL PF05701.6 ETS84564.1 - 0.074 11.4 169.4 0.012 14.0 33.7 5.0 2 2 1 3 3 3 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 ETS84564.1 - 0.12 12.1 154.7 0.086 12.5 14.2 10.2 4 3 3 8 8 8 0 TPR/MLP1/MLP2-like protein ING PF12998.2 ETS84564.1 - 0.58 10.4 0.0 0.58 10.4 0.0 9.9 4 2 4 9 9 7 0 Inhibitor of growth proteins N-terminal histone-binding HOOK PF05622.7 ETS84564.1 - 1.4 6.6 141.5 0.15 9.8 61.1 4.4 2 2 1 3 3 3 0 HOOK protein Spc7 PF08317.6 ETS84564.1 - 1.6 7.3 140.7 0.027 13.1 12.4 7.6 3 2 2 7 7 7 0 Spc7 kinetochore protein DUF2296 PF10058.4 ETS84565.1 - 8.1e-19 67.1 0.1 1.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RanBP PF00641.13 ETS84565.1 - 0.067 12.3 1.0 0.15 11.2 0.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DIOX_N PF14226.1 ETS84566.1 - 1.4e-17 64.2 0.0 3.8e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS84566.1 - 5.4e-16 58.7 0.0 8.9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 ETS84567.1 - 7.6e-77 258.7 26.6 8.8e-77 258.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84567.1 - 1.7e-22 79.6 26.7 6.7e-21 74.3 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS84567.1 - 0.00034 18.9 1.7 0.00034 18.9 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ring_hydroxyl_A PF00848.14 ETS84567.1 - 0.085 12.4 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Amidohydro_1 PF01979.15 ETS84568.1 - 4.7e-30 105.3 0.0 6.2e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 ETS84568.1 - 1.6e-09 37.5 0.4 1.5e-05 24.4 0.0 3.2 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 ETS84568.1 - 4.3e-08 33.5 0.4 0.00018 21.6 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 ETS84568.1 - 6.2e-05 22.7 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 ETS84568.1 - 0.00019 20.4 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase MARVEL PF01284.18 ETS84569.1 - 0.0006 19.6 9.8 0.001 18.9 6.8 1.4 1 0 0 1 1 1 1 Membrane-associating domain Serinc PF03348.10 ETS84569.1 - 0.029 13.0 0.1 0.049 12.3 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) 7TMR-DISM_7TM PF07695.6 ETS84569.1 - 2.5 7.7 9.2 0.21 11.2 3.0 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling ENTH PF01417.15 ETS84570.1 - 2.9e-46 156.3 0.1 4.3e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 ETS84570.1 - 0.00024 19.8 0.0 0.00036 19.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain PAT1 PF09770.4 ETS84570.1 - 0.32 9.2 12.3 0.51 8.5 8.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pro_isomerase PF00160.16 ETS84571.1 - 5.7e-40 137.0 0.2 7.3e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.7 ETS84572.1 - 8.7e-83 278.2 0.0 1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 ETS84572.1 - 1.2e-05 25.1 0.1 2.5e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.12 ETS84572.1 - 0.047 13.1 0.2 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit RPA_C PF08784.6 ETS84572.1 - 0.14 12.6 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal TPR_11 PF13414.1 ETS84573.1 - 8.8e-54 179.0 26.4 3.9e-17 61.6 0.3 6.4 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 ETS84573.1 - 3e-41 137.3 27.8 1.1e-06 27.9 0.5 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 ETS84573.1 - 2.3e-32 108.2 26.5 0.00018 21.1 0.1 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 ETS84573.1 - 4.2e-17 61.8 15.4 2.5e-10 40.1 1.0 6.2 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS84573.1 - 1.4e-15 56.3 12.3 0.49 11.1 0.0 9.0 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 ETS84573.1 - 9.5e-15 54.8 10.8 0.0069 17.0 0.3 6.6 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS84573.1 - 8.2e-14 50.2 17.5 0.0009 18.8 0.2 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 ETS84573.1 - 1.9e-13 49.4 7.2 0.062 13.5 0.1 8.1 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 ETS84573.1 - 1.3e-10 41.0 0.5 0.0011 18.8 0.0 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS84573.1 - 2.4e-10 39.3 9.0 0.00058 19.4 0.0 6.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS84573.1 - 4.8e-09 36.4 11.0 0.019 15.2 0.2 6.6 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 ETS84573.1 - 0.00022 21.0 0.1 0.2 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS84573.1 - 0.0068 16.5 3.7 0.0068 16.5 2.6 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS84573.1 - 0.085 13.3 20.5 0.66 10.5 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 ETS84574.1 - 3e-48 164.4 13.4 4e-48 164.0 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 ETS84574.1 - 0.12 11.8 1.3 0.44 10.0 0.0 2.5 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase ATP_transf PF09830.4 ETS84576.1 - 1.3e-15 56.9 0.1 2.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Rad4 PF03835.10 ETS84578.1 - 1.1e-16 60.5 3.6 2.7e-16 59.2 2.5 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 ETS84578.1 - 1.2e-13 51.2 2.0 2.7e-13 50.1 1.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily adh_short PF00106.20 ETS84579.1 - 4.3e-14 52.7 0.0 6.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84579.1 - 2e-08 34.3 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS84579.1 - 5.1e-06 26.6 0.1 8.4e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS84579.1 - 1.1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS84579.1 - 0.00071 19.2 0.1 0.00096 18.8 0.0 1.3 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 ETS84579.1 - 0.025 14.5 0.0 0.29 11.0 0.0 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 ETS84579.1 - 0.065 12.4 0.1 0.082 12.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_18 PF00704.23 ETS84580.1 - 5.5e-15 55.6 1.7 3.4e-14 53.0 1.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS84580.1 - 0.00013 21.8 23.8 0.00048 20.0 16.5 2.0 1 0 0 1 1 1 1 Chitin recognition protein Sec61_beta PF03911.11 ETS84581.1 - 1.2e-20 73.0 1.3 1.6e-20 72.6 0.9 1.2 1 0 0 1 1 1 1 Sec61beta family CFEM PF05730.6 ETS84582.1 - 4.7e-16 58.3 13.6 7.8e-16 57.6 9.5 1.4 1 0 0 1 1 1 1 CFEM domain Tyrosinase PF00264.15 ETS84583.1 - 1.1e-32 114.0 2.8 1.5e-32 113.5 2.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase EVI2A PF05399.6 ETS84583.1 - 0.2 10.9 0.2 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Glyco_transf_28 PF03033.15 ETS84585.1 - 8.2e-21 74.2 0.0 4.2e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS84585.1 - 1.6e-06 26.9 0.0 2.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS84585.1 - 0.00096 18.8 1.3 0.0024 17.5 0.0 2.2 2 1 1 3 3 3 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 ETS84585.1 - 0.0019 18.2 0.0 0.0074 16.4 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain UIM PF02809.15 ETS84585.1 - 0.063 12.8 32.1 1.2 8.9 0.8 7.1 7 0 0 7 7 7 0 Ubiquitin interaction motif adh_short PF00106.20 ETS84586.1 - 8.5e-17 61.5 0.1 2.5e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS84586.1 - 1.7e-09 37.5 0.1 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 ETS84586.1 - 0.0024 17.9 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 ETS84587.1 - 2.1e-14 53.0 0.0 3.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84587.1 - 5.3e-08 32.6 7.0 1.1e-07 31.5 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIF PF03031.13 ETS84588.1 - 2.4e-35 121.5 0.0 3.6e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RP-C_C PF11800.3 ETS84588.1 - 3 7.4 8.2 0.086 12.5 1.0 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF605 PF04652.11 ETS84590.1 - 4.3e-92 309.4 19.4 6.9e-92 308.7 13.4 1.3 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 ETS84590.1 - 4.9 5.2 29.2 7.6 4.6 20.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredoxin PF00085.15 ETS84591.1 - 6.3e-33 112.5 0.4 6.9e-27 93.1 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.1 ETS84591.1 - 2.5e-06 27.5 0.3 0.0026 17.8 0.0 4.2 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS84591.1 - 3.8e-05 23.8 6.9 0.0011 19.1 0.2 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain ERp29_N PF07912.8 ETS84591.1 - 0.0028 17.5 0.1 1.5 8.7 0.0 2.8 2 1 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 ETS84591.1 - 0.0034 17.3 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 ETS84591.1 - 0.014 15.2 0.0 5 7.0 0.0 2.9 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 ETS84591.1 - 0.04 13.7 0.1 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain EutB PF06751.6 ETS84591.1 - 0.14 10.4 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) RNase_PH PF01138.16 ETS84592.1 - 2.5e-34 118.4 1.0 3.6e-34 117.9 0.7 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 ETS84592.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fungal_trans PF04082.13 ETS84593.1 - 0.0025 16.7 1.0 0.004 16.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.13 ETS84594.1 - 5.8e-33 114.2 0.1 9.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADH_zinc_N PF00107.21 ETS84595.1 - 2.4e-27 95.0 1.4 3.9e-27 94.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS84595.1 - 8.6e-19 68.6 0.2 2.9e-18 66.9 0.0 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS84595.1 - 5.2e-12 45.5 0.0 1.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 ETS84595.1 - 0.00059 19.8 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.16 ETS84595.1 - 0.0027 17.2 0.1 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 ETS84595.1 - 0.033 13.7 0.5 0.061 12.8 0.1 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 ETS84596.1 - 1.2e-28 100.1 7.6 1.6e-28 99.6 5.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84596.1 - 6.4e-26 91.5 0.3 7.6e-26 91.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84596.1 - 5.9e-13 48.8 5.1 8.3e-13 48.3 3.6 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS84596.1 - 0.0083 15.7 1.2 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 ETS84596.1 - 0.023 14.1 0.4 0.058 12.8 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 ETS84596.1 - 0.075 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TauD PF02668.11 ETS84597.1 - 1e-51 176.0 0.0 1.4e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hemerythrin PF01814.18 ETS84598.1 - 7.5e-10 39.0 1.1 1.1e-09 38.5 0.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2095 PF09868.4 ETS84598.1 - 0.065 13.0 0.2 5.1 6.8 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) MFS_1 PF07690.11 ETS84599.1 - 1.8e-42 145.3 23.1 1.8e-42 145.3 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS84600.1 - 2.7e-21 75.5 0.1 5e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84600.1 - 2.6e-07 30.4 17.6 2.6e-07 30.4 9.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_N PF08403.5 ETS84600.1 - 0.072 12.4 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal Aa_trans PF01490.13 ETS84601.1 - 1.1e-37 129.5 36.2 1.3e-37 129.2 25.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PIG-P PF08510.7 ETS84601.1 - 1.5 8.4 6.4 1.1 8.9 0.7 2.8 2 0 0 2 2 2 0 PIG-P S1FA PF04689.8 ETS84601.1 - 3.7 7.4 7.1 13 5.7 0.1 3.3 3 0 0 3 3 3 0 DNA binding protein S1FA DUF3176 PF11374.3 ETS84602.1 - 1e-34 118.7 4.9 1.2e-34 118.4 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) FAD_binding_3 PF01494.14 ETS84603.1 - 1.7e-29 103.0 0.2 9.6e-29 100.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS84603.1 - 2.7e-05 23.2 1.7 0.071 12.0 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS84603.1 - 0.00039 20.3 0.7 0.0032 17.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS84603.1 - 0.00044 19.2 0.7 0.0018 17.2 0.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS84603.1 - 0.00047 19.3 0.3 0.08 11.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.5 ETS84603.1 - 0.00057 18.8 0.0 0.0032 16.3 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 ETS84603.1 - 0.0016 18.7 0.2 0.0087 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS84603.1 - 0.0025 16.5 0.7 0.0037 15.9 0.2 1.4 1 1 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 ETS84603.1 - 0.0028 16.7 0.1 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS84603.1 - 0.0037 15.7 0.0 0.0064 15.0 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 ETS84603.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Glyco_hydro_12 PF01670.11 ETS84604.1 - 2.6e-20 72.8 2.1 5.6e-20 71.6 1.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Lipoprotein_15 PF03640.10 ETS84604.1 - 0.37 10.2 3.2 1.6 8.2 0.2 2.4 2 0 0 2 2 2 0 Secreted repeat of unknown function Aldedh PF00171.17 ETS84605.1 - 7.7e-145 482.7 0.0 9e-145 482.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS84605.1 - 0.021 13.5 0.0 0.12 11.0 0.0 2.1 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) p450 PF00067.17 ETS84606.1 - 1.1e-69 235.2 0.0 2.4e-69 234.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Transformer PF06495.6 ETS84607.1 - 0.091 12.6 6.8 0.093 12.6 4.7 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF4233 PF14017.1 ETS84608.1 - 0.034 14.0 1.1 0.11 12.4 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Abhydrolase_3 PF07859.8 ETS84609.1 - 8.1e-22 77.8 0.6 1.1e-21 77.4 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84609.1 - 2.3e-06 27.4 0.6 4.3e-06 26.5 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 ETS84609.1 - 5.9e-05 21.8 0.0 8.3e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Clr5 PF14420.1 ETS84611.1 - 4.7e-13 48.8 0.7 8.8e-13 47.9 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain Oxidored_FMN PF00724.15 ETS84613.1 - 3.4e-90 302.4 0.0 3.9e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_6 PF12697.2 ETS84614.1 - 4.2e-12 46.4 1.4 6.3e-12 45.8 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 ETS84614.1 - 6.4e-10 38.6 1.3 7.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 ETS84614.1 - 7.3e-09 35.5 0.5 1.2e-08 34.8 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS84614.1 - 0.0023 17.1 0.6 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family ABC2_membrane PF01061.19 ETS84616.1 - 9.7e-85 282.9 59.6 3.9e-44 150.3 17.1 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 ETS84616.1 - 4.9e-37 127.2 0.0 3.9e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS84616.1 - 1.1e-33 114.9 8.4 5.5e-29 99.8 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 ETS84616.1 - 8.3e-17 61.0 0.0 2.5e-16 59.5 0.0 1.8 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS84616.1 - 1.5e-08 34.2 0.0 9.6e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 ETS84616.1 - 2.1e-05 24.0 0.6 0.00071 19.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 ETS84616.1 - 2.3e-05 23.5 47.9 0.0052 15.8 17.2 3.3 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 ETS84616.1 - 2.8e-05 24.1 1.5 0.00016 21.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETS84616.1 - 3.8e-05 22.9 0.0 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS84616.1 - 0.00011 22.1 0.8 0.042 13.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 ETS84616.1 - 0.00027 20.4 0.3 0.035 13.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS84616.1 - 0.00028 21.6 0.0 0.11 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS84616.1 - 0.00087 19.6 0.0 0.027 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS84616.1 - 0.0027 17.8 0.3 0.33 11.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 ETS84616.1 - 0.017 15.5 0.0 6.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SMC_N PF02463.14 ETS84616.1 - 0.039 13.1 0.0 0.82 8.8 0.0 2.7 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS84616.1 - 0.044 13.7 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS84616.1 - 0.048 13.2 0.7 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 ETS84616.1 - 0.048 13.1 0.1 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 ETS84616.1 - 0.049 13.2 1.3 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 ETS84616.1 - 0.13 12.2 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 ETS84616.1 - 0.14 11.7 1.1 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 ETS84616.1 - 0.47 10.2 2.1 7.1 6.4 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain SnoaL_4 PF13577.1 ETS84617.1 - 2.5e-11 43.5 0.3 3.1e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Cupin_5 PF06172.6 ETS84617.1 - 0.058 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Cupin superfamily (DUF985) Ribonuc_L-PSP PF01042.16 ETS84618.1 - 9e-10 38.3 0.1 3.5e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Endoribonuclease L-PSP NmrA PF05368.8 ETS84619.1 - 1.6e-14 53.6 0.0 8.3e-14 51.4 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS84619.1 - 1.7e-08 34.7 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS84619.1 - 0.0015 18.0 0.2 0.012 15.0 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS84619.1 - 0.033 13.8 0.0 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 ETS84619.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.20 ETS84620.1 - 4.9e-19 68.4 0.0 8.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS84620.1 - 2.1e-10 40.1 0.0 1.7e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Aldo_ket_red PF00248.16 ETS84621.1 - 2.4e-46 157.8 0.0 3.7e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 ETS84621.1 - 4.6e-23 81.7 0.0 8.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 ETS84621.1 - 3.7e-21 75.7 1.3 6e-21 75.0 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 ETS84621.1 - 2.2e-16 59.6 0.0 4.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.18 ETS84622.1 - 3.4e-25 88.1 1.0 6e-25 87.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain HET PF06985.6 ETS84623.1 - 2e-26 92.8 0.2 4.7e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 ETS84624.1 - 2.4e-18 66.6 0.0 5e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84624.1 - 6e-09 35.8 0.1 9e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS84624.1 - 8.8e-06 25.6 0.0 7.4e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS84624.1 - 0.00032 20.7 0.1 0.00065 19.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS84624.1 - 0.0017 17.8 0.1 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS84624.1 - 0.051 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RMF PF04957.7 ETS84624.1 - 0.053 13.2 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosome modulation factor TrbH PF07283.6 ETS84624.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Conjugal transfer protein TrbH MFS_1 PF07690.11 ETS84626.1 - 2.4e-33 115.3 76.9 9e-28 96.9 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS84626.1 - 4.5e-06 26.3 10.7 0.029 14.1 2.9 4.2 4 0 0 4 4 4 2 MFS_1 like family MFS_2 PF13347.1 ETS84626.1 - 0.00025 19.5 25.4 0.00025 19.5 17.6 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein Zn_clus PF00172.13 ETS84627.1 - 2.3e-08 33.8 10.4 4e-08 33.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS84627.1 - 9.5e-08 31.2 0.0 1.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.22 ETS84628.1 - 3.4e-26 92.1 0.0 5.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS84628.1 - 7.8e-05 22.7 0.1 0.0074 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 ETS84628.1 - 0.00011 21.4 0.2 0.00021 20.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS84628.1 - 0.0016 17.8 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 ETS84628.1 - 0.0017 17.8 2.0 0.0025 17.2 0.6 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 ETS84628.1 - 0.0034 16.6 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ArgK PF03308.11 ETS84628.1 - 0.004 15.9 0.4 0.0078 15.0 0.3 1.3 1 0 0 1 1 1 1 ArgK protein FtsK_SpoIIIE PF01580.13 ETS84628.1 - 0.04 13.3 0.2 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.2 ETS84628.1 - 0.11 11.5 14.3 0.017 14.2 7.0 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_10 PF12846.2 ETS84628.1 - 0.15 11.4 0.3 0.27 10.6 0.2 1.4 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 ETS84628.1 - 0.16 11.8 0.0 0.52 10.2 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 ETS84628.1 - 0.38 9.8 0.6 0.67 9.0 0.4 1.2 1 0 0 1 1 1 0 KaiC IIGP PF05049.8 ETS84628.1 - 0.43 9.3 0.6 0.67 8.6 0.5 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.12 ETS84628.1 - 0.74 9.5 2.4 1.2 8.8 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 TILa PF12714.2 ETS84628.1 - 1.5 8.6 10.1 2.9 7.7 1.0 2.8 2 0 0 2 2 2 0 TILa domain UCH PF00443.24 ETS84629.1 - 1.9e-43 148.5 0.0 2.8e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 ETS84629.1 - 1.7e-22 79.2 12.1 2.4e-19 69.1 1.2 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 ETS84629.1 - 1.5e-21 75.5 0.1 3e-10 39.6 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 ETS84629.1 - 2.8e-16 59.8 0.1 1.7e-12 47.4 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NifU_N PF01592.11 ETS84630.1 - 7.8e-51 171.2 0.0 1e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Methyltransf_16 PF10294.4 ETS84631.1 - 1.1e-27 96.5 0.0 7.6e-27 93.8 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 ETS84631.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84631.1 - 0.0087 16.6 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PhyH PF05721.8 ETS84632.1 - 4.2e-08 33.4 0.1 6.2e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS84632.1 - 8.4e-05 21.2 0.1 0.07 11.6 0.1 2.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) GFO_IDH_MocA PF01408.17 ETS84633.1 - 6.7e-17 62.1 0.2 9e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 ETS84633.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 ETS84633.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 ETS84633.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 ETS84634.1 - 2.6e-19 69.9 0.1 4.7e-15 56.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS84634.1 - 2.2e-16 60.2 0.7 1.4e-09 38.1 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS84634.1 - 0.0043 16.7 0.2 0.036 13.7 0.2 2.0 1 1 1 2 2 2 2 KR domain AAA_17 PF13207.1 ETS84635.1 - 3.2e-06 27.9 0.0 2.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 ETS84635.1 - 6.5e-06 25.3 0.0 1.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 ETS84635.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 ETS84635.1 - 2.6e-05 23.8 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 ETS84635.1 - 0.00022 21.0 0.1 0.0011 18.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS84635.1 - 0.00032 20.9 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS84635.1 - 0.00034 19.5 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 ETS84635.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS84635.1 - 0.0018 17.9 1.3 0.0074 16.0 0.1 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 ETS84635.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ETS84635.1 - 0.0025 17.5 0.1 0.013 15.1 0.0 2.1 2 1 1 3 3 2 1 NTPase Mg_chelatase PF01078.16 ETS84635.1 - 0.0034 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETS84635.1 - 0.0052 16.1 0.5 0.029 13.7 0.1 2.3 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 ETS84635.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 NACHT domain ArgK PF03308.11 ETS84635.1 - 0.021 13.5 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 ETS84635.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 ETS84635.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 ETS84635.1 - 0.027 13.9 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 ETS84635.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 ETS84635.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SE PF00437.15 ETS84635.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 ETS84635.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS84635.1 - 0.052 13.4 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 ETS84635.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 ETS84635.1 - 0.067 12.8 0.1 0.17 11.5 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 ETS84635.1 - 0.071 13.4 0.0 0.089 13.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 ETS84635.1 - 0.09 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.1 ETS84635.1 - 0.12 12.3 0.1 0.43 10.5 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_PrkA PF08298.6 ETS84635.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA PF00004.24 ETS84636.1 - 3.3e-08 33.7 0.0 6.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS84636.1 - 0.00077 20.2 0.0 0.0031 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 ETS84636.1 - 0.0017 17.8 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 ETS84636.1 - 0.0054 16.8 0.1 0.022 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 ETS84636.1 - 0.012 15.3 0.1 0.079 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 ETS84636.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 ETS84636.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS84636.1 - 0.075 13.0 0.6 0.25 11.2 0.1 1.8 1 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 ETS84636.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.4 ETS84637.1 - 0.054 12.6 2.9 0.073 12.2 2.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 T2SF PF00482.18 ETS84637.1 - 0.099 12.5 0.4 0.24 11.3 0.2 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1484 PF07363.6 ETS84637.1 - 0.21 11.9 5.0 0.34 11.2 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) MoeA_N PF03453.12 ETS84638.1 - 0.0034 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) ketoacyl-synt PF00109.21 ETS84640.1 - 1.6e-67 227.6 0.0 1.6e-67 227.6 0.0 2.6 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS84640.1 - 3.9e-63 213.7 0.0 6.9e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 ETS84640.1 - 9.9e-61 204.5 0.8 3.6e-60 202.7 0.5 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 ETS84640.1 - 2.7e-53 181.0 0.1 4.1e-53 180.4 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS84640.1 - 5.8e-46 156.4 0.2 5.8e-46 156.4 0.2 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS84640.1 - 2.1e-34 117.8 0.2 5.8e-34 116.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 ETS84640.1 - 4.6e-20 71.4 0.1 2e-18 66.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 ETS84640.1 - 1.4e-14 54.3 0.0 4.1e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS84640.1 - 2.4e-14 54.3 0.0 1e-13 52.2 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS84640.1 - 7.3e-10 38.5 0.1 2.7e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 ETS84640.1 - 1.4e-09 37.9 0.0 4.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 ETS84640.1 - 2.1e-08 34.2 0.4 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 ETS84640.1 - 1.8e-07 31.7 0.0 5e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84640.1 - 2e-05 24.2 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS84640.1 - 0.0003 21.2 0.0 0.0016 18.8 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS84640.1 - 0.00068 19.6 0.1 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 ETS84640.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 ETS84640.1 - 0.0016 17.6 0.0 0.0065 15.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS84640.1 - 0.0065 16.8 0.0 0.024 15.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.15 ETS84640.1 - 0.24 11.5 0.0 0.72 9.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RrnaAD PF00398.15 ETS84640.1 - 0.34 9.8 0.0 0.6 9.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.17 ETS84641.1 - 2.7e-47 161.3 0.0 3.6e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS84642.1 - 1.8e-31 109.1 60.4 4.1e-26 91.5 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 ETS84643.1 - 4.7e-47 159.7 0.0 7e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS84643.1 - 3.9e-28 98.6 27.7 1e-20 74.3 10.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS84643.1 - 2.3e-12 46.6 0.6 1.6e-05 24.2 0.2 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS84643.1 - 1.2e-08 35.2 0.4 0.077 12.9 0.0 3.8 2 2 1 4 4 4 2 AAA domain AAA_22 PF13401.1 ETS84643.1 - 5.9e-08 32.9 0.0 0.00049 20.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS84643.1 - 1.1e-07 32.6 0.0 0.0052 17.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS84643.1 - 1e-06 28.8 0.7 0.0054 16.7 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS84643.1 - 1.6e-05 24.3 0.1 0.0035 16.8 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 ETS84643.1 - 1.6e-05 25.1 0.0 0.47 10.6 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 ETS84643.1 - 3e-05 23.9 0.0 0.11 12.4 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 ETS84643.1 - 3.3e-05 24.1 0.0 0.086 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 ETS84643.1 - 0.00013 21.2 0.0 0.039 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 ETS84643.1 - 0.0003 20.5 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase AAA_25 PF13481.1 ETS84643.1 - 0.00039 19.8 0.0 0.085 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 ETS84643.1 - 0.00052 20.5 0.0 0.08 13.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 ETS84643.1 - 0.00065 20.0 0.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS84643.1 - 0.00067 19.5 0.0 0.58 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 ETS84643.1 - 0.00097 18.2 0.0 1.3 8.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 ETS84643.1 - 0.002 17.6 0.7 1.3 8.4 0.0 3.5 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 ETS84643.1 - 0.0053 16.4 0.2 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 ETS84643.1 - 0.0061 16.2 0.2 0.36 10.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PduV-EutP PF10662.4 ETS84643.1 - 0.007 15.8 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 ETS84643.1 - 0.011 15.2 0.6 1.4 8.4 0.3 3.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 ETS84643.1 - 0.012 15.6 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 ETS84643.1 - 0.024 14.3 0.0 0.71 9.5 0.0 2.5 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.1 ETS84643.1 - 0.034 14.0 0.4 0.66 9.9 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 ETS84643.1 - 0.045 12.6 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 ETS84643.1 - 0.049 12.7 0.0 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 ETS84643.1 - 0.073 12.7 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 ETS84643.1 - 0.088 12.2 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 ETS84643.1 - 0.1 12.3 0.2 3.8 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS84643.1 - 0.1 12.7 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 ETS84643.1 - 0.12 12.2 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 ETS84643.1 - 0.33 9.4 2.3 11 4.4 0.0 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class P5-ATPase PF12409.3 ETS84644.1 - 1.4 8.8 5.6 1.9 8.3 1.6 2.3 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF4573 PF15140.1 ETS84645.1 - 2.6e-06 27.1 0.0 0.0045 16.6 0.0 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) DBD_Tnp_Hermes PF10683.4 ETS84645.1 - 0.00071 18.9 7.7 14 5.1 0.1 6.2 1 1 4 6 6 6 1 Hermes transposase DNA-binding domain HgmA PF04209.8 ETS84645.1 - 0.0017 16.8 0.5 2.4 6.4 0.0 2.9 1 1 2 3 3 3 2 homogentisate 1,2-dioxygenase CDC48_2 PF02933.12 ETS84645.1 - 0.012 15.2 7.9 25 4.5 0.1 5.7 4 4 1 5 5 5 0 Cell division protein 48 (CDC48), domain 2 DUF1958 PF09211.5 ETS84645.1 - 0.049 13.7 3.8 58 3.8 0.1 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF1958) XH PF03469.9 ETS84645.1 - 0.16 11.6 0.1 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 XH domain DUF1996 PF09362.5 ETS84647.1 - 1e-84 283.8 1.6 1.4e-84 283.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 ETS84647.1 - 1.2e-20 73.2 9.6 1.2e-20 73.2 6.6 2.3 3 0 0 3 3 3 1 WSC domain CoA_transf_3 PF02515.12 ETS84649.1 - 2.8e-31 108.2 0.0 3e-28 98.3 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Sugar_tr PF00083.19 ETS84650.1 - 1.1e-76 258.2 24.0 1.3e-76 258.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84650.1 - 7.7e-20 70.8 55.2 3.1e-11 42.6 1.0 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 ETS84651.1 - 2.8e-06 26.1 1.2 9.6e-06 24.4 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF706 PF05153.10 ETS84652.1 - 1.6e-129 430.6 2.5 2e-129 430.2 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) MFS_1 PF07690.11 ETS84653.1 - 1.4e-35 122.6 37.4 2.2e-32 112.1 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 ETS84653.1 - 4.1e-05 23.5 0.2 4.1e-05 23.5 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) TRI12 PF06609.8 ETS84653.1 - 5.4e-05 21.5 3.3 5.4e-05 21.5 2.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Moricin PF06451.6 ETS84653.1 - 0.16 11.4 0.2 0.42 10.1 0.1 1.7 1 0 0 1 1 1 0 Moricin MFS_1 PF07690.11 ETS84654.1 - 2.6e-21 75.7 33.8 2.6e-14 52.7 17.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84654.1 - 0.32 9.5 26.9 0.019 13.5 2.6 3.0 2 1 1 3 3 3 0 Sugar (and other) transporter DUF4537 PF15057.1 ETS84655.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Glyco_hydro_3 PF00933.16 ETS84656.1 - 6.8e-81 271.5 0.0 1e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS84656.1 - 3.8e-70 235.9 0.0 1e-69 234.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS84656.1 - 3.2e-25 87.8 0.4 7e-25 86.7 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS84656.1 - 7.1e-17 61.3 0.0 1.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.1 ETS84657.1 - 7e-53 179.2 0.7 9.1e-53 178.8 0.5 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3373 PF11853.3 ETS84657.1 - 0.069 11.6 0.2 0.09 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DivIC PF04977.10 ETS84657.1 - 0.35 10.4 6.4 0.095 12.1 1.7 2.1 2 0 0 2 2 2 0 Septum formation initiator DASH_Dad3 PF08656.5 ETS84657.1 - 0.36 10.5 2.6 15 5.3 0.5 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF4407 PF14362.1 ETS84657.1 - 0.7 8.7 4.1 0.86 8.5 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 ETS84657.1 - 0.8 9.2 6.9 1.2 8.7 4.7 1.4 1 1 0 1 1 1 0 IncA protein TraC PF07820.7 ETS84657.1 - 9.2 6.5 7.0 10 6.3 0.0 2.9 3 1 1 4 4 4 0 TraC-like protein Peptidase_C2 PF00648.16 ETS84658.1 - 5.1e-56 189.8 3.9 6.1e-37 127.2 0.4 2.5 2 1 0 2 2 2 2 Calpain family cysteine protease FmdE PF02663.9 ETS84658.1 - 0.23 11.3 1.7 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon HET PF06985.6 ETS84659.1 - 1.2e-22 80.5 0.4 2.4e-22 79.6 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIM PF00121.13 ETS84660.1 - 9.6e-60 201.6 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MdcG PF10620.4 ETS84660.1 - 0.059 12.8 0.9 0.087 12.3 0.7 1.1 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG LacAB_rpiB PF02502.13 ETS84661.1 - 3.6e-43 146.5 0.4 4.1e-43 146.3 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Dak1 PF02733.12 ETS84662.1 - 1.2e-106 355.9 0.0 1.6e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS84662.1 - 4.2e-41 140.5 0.3 9.5e-41 139.3 0.2 1.6 1 0 0 1 1 1 1 DAK2 domain DUF3456 PF11938.3 ETS84662.1 - 0.027 14.4 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DUF4261 PF14080.1 ETS84662.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) NAD_binding_11 PF14833.1 ETS84663.1 - 6e-39 132.8 0.0 7.2e-26 90.6 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 ETS84663.1 - 9.1e-37 126.4 0.3 1.6e-36 125.6 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS84663.1 - 1.5e-06 28.5 0.1 6.6e-06 26.4 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 ETS84663.1 - 0.0011 18.6 0.3 0.0024 17.5 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS84663.1 - 0.0047 16.6 0.4 3.4 7.3 0.0 2.8 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 ETS84663.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 ETS84663.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 ETS84663.1 - 0.042 12.9 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS84663.1 - 0.057 12.7 0.2 0.28 10.5 0.1 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F_bP_aldolase PF01116.15 ETS84664.1 - 4.6e-83 278.6 0.0 5.2e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-UBR PF02207.15 ETS84665.1 - 2e-16 59.4 6.9 2e-16 59.4 4.8 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 ETS84666.1 - 4.1e-138 459.7 0.0 4.1e-138 459.7 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 ETS84666.1 - 2.5e-35 121.7 41.4 2.5e-35 121.7 28.7 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 ETS84666.1 - 4e-21 75.7 0.1 1.1e-20 74.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS84666.1 - 8.2e-08 31.6 0.0 5.3e-06 25.7 0.0 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETS84666.1 - 5.2e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 ETS84666.1 - 0.0021 17.5 0.2 0.015 14.7 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 ETS84666.1 - 0.003 17.1 0.1 0.019 14.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FAD_binding_4 PF01565.18 ETS84667.1 - 9.7e-20 70.4 2.7 2.5e-19 69.1 1.9 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS84667.1 - 4.2e-10 39.3 0.0 8.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3176 PF11374.3 ETS84668.1 - 0.03 14.1 0.7 0.03 14.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Myticin-prepro PF10690.4 ETS84668.1 - 0.14 12.1 1.5 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel DUF3816 PF12822.2 ETS84668.1 - 1.1 9.1 11.8 0.28 11.0 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) DUF1049 PF06305.6 ETS84668.1 - 2.8 7.4 14.6 3.4 7.2 0.1 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) DUF1275 PF06912.6 ETS84668.1 - 3.5 6.7 10.0 0.083 12.0 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) MFS_1 PF07690.11 ETS84669.1 - 3.6e-37 127.9 36.1 3.6e-37 127.9 25.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 ETS84670.1 - 2.6e-25 89.2 0.2 3.2e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84670.1 - 2.2e-21 76.7 0.0 3e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84670.1 - 1.9e-10 40.7 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF272 PF03312.10 ETS84670.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF272) F_bP_aldolase PF01116.15 ETS84671.1 - 2.3e-78 263.2 0.2 2.6e-78 263.0 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 ETS84671.1 - 0.046 12.7 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family LacAB_rpiB PF02502.13 ETS84672.1 - 3.1e-42 143.5 0.1 3.5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 ETS84672.1 - 0.02 14.7 0.3 0.095 12.5 0.0 1.9 2 0 0 2 2 2 0 Glycine-rich SFCGS Fungal_trans_2 PF11951.3 ETS84673.1 - 2.9e-07 29.4 0.1 0.0036 15.9 0.0 2.9 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84673.1 - 3.9e-07 29.8 7.2 8.3e-07 28.8 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.12 ETS84674.1 - 9.4e-109 362.9 0.0 1.4e-108 362.3 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 ETS84674.1 - 1.4e-39 135.5 3.0 1.4e-39 135.5 2.1 1.9 2 0 0 2 2 2 1 DAK2 domain RP1-2 PF12042.3 ETS84674.1 - 0.00045 19.9 2.4 0.00045 19.9 1.7 2.4 2 0 0 2 2 2 1 Tubuliform egg casing silk strands structural domain Ldh_1_N PF00056.18 ETS84674.1 - 0.047 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Peptidase_M13_N PF05649.8 ETS84676.1 - 3.6e-84 283.0 0.0 4.8e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 ETS84676.1 - 3.9e-54 182.9 0.6 6.3e-54 182.2 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M13 PBP1_TM PF14812.1 ETS84676.1 - 0.04 14.2 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.7 ETS84677.1 - 3.2e-36 122.9 37.4 2.5e-05 24.7 0.1 13.4 15 0 0 15 15 15 10 Sel1 repeat DUF4328 PF14219.1 ETS84677.1 - 0.021 14.1 0.3 0.052 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) WD40 PF00400.27 ETS84678.1 - 2.7e-13 49.2 0.7 0.00046 19.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ASL_C2 PF14698.1 ETS84678.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal FRG1 PF06229.7 ETS84679.1 - 3e-58 196.4 0.4 4.4e-58 195.8 0.3 1.3 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 ETS84679.1 - 0.0093 16.0 0.5 0.11 12.6 0.0 2.7 3 1 1 4 4 4 1 Fascin domain Selenoprotein_S PF06936.6 ETS84679.1 - 2.8 7.4 6.4 7.4 6.0 0.2 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) FAM180 PF15173.1 ETS84680.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 FAM180 family 2OG-FeII_Oxy PF03171.15 ETS84680.1 - 0.012 15.8 0.0 0.058 13.6 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3176 PF11374.3 ETS84681.1 - 2e-28 98.5 0.1 4.4e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.13 ETS84682.1 - 3.5e-16 58.8 0.1 8.3e-16 57.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84682.1 - 1.9e-05 24.5 7.9 3.5e-05 23.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS84684.1 - 7.4e-52 176.3 0.0 9.5e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 ETS84684.1 - 0.085 12.4 0.9 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Reticulon LCM PF04072.9 ETS84685.1 - 7.2e-36 123.4 0.4 1.1e-35 122.9 0.3 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase adh_short PF00106.20 ETS84686.1 - 9.4e-13 48.4 0.1 2.7e-12 46.9 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS84686.1 - 7e-06 25.8 0.1 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS84686.1 - 3.6e-05 23.8 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS84686.1 - 8.7e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 ETS84686.1 - 0.031 13.8 0.0 0.48 10.0 0.1 2.1 1 1 1 2 2 2 0 YjeF-related protein N-terminus ApbA PF02558.11 ETS84686.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.23 ETS84687.1 - 1.4e-63 214.7 0.0 2.2e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS84687.1 - 4.4e-12 46.7 0.1 1.7e-11 44.8 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_5 PF12695.2 ETS84689.1 - 2.1e-05 24.3 0.1 3.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS84689.1 - 0.00034 20.2 0.0 0.0031 17.1 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS84689.1 - 0.00034 20.5 0.7 0.0019 18.1 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 ETS84689.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 ETS84689.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.3 ETS84689.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 ETS84689.1 - 0.023 14.9 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 ETS84689.1 - 0.045 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 ETS84689.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 ETS84689.1 - 0.14 11.5 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GST_N PF02798.15 ETS84690.1 - 2.3e-11 43.7 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS84690.1 - 1.4e-07 31.6 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS84690.1 - 1.6e-06 27.9 0.0 1.2e-05 25.2 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS84690.1 - 2.6e-06 27.8 0.0 5.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS84690.1 - 1.3e-05 24.9 0.0 6.7e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS84690.1 - 4.9e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Elf1 PF05129.8 ETS84691.1 - 0.82 9.4 4.2 28 4.4 2.4 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Fungal_trans PF04082.13 ETS84693.1 - 1.3e-25 89.7 1.1 2.4e-25 88.9 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84693.1 - 6.3e-09 35.5 10.3 1.2e-08 34.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RuBisCO_small PF00101.15 ETS84693.1 - 0.017 14.9 0.2 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain adh_short PF00106.20 ETS84694.1 - 5.7e-17 62.1 0.0 9.1e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84694.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain PI-PLC-X PF00388.14 ETS84695.1 - 0.025 13.9 0.0 0.14 11.5 0.0 2.1 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain NACHT PF05729.7 ETS84698.1 - 3.3e-15 56.1 0.0 6.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 ETS84698.1 - 2.2e-12 46.4 0.1 9.6e-12 44.3 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.1 ETS84698.1 - 1.7e-06 27.9 0.0 0.0018 18.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 ETS84698.1 - 5.4e-06 26.6 0.0 3.5e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 ETS84698.1 - 4e-05 23.4 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 ETS84698.1 - 5.8e-05 23.1 0.1 0.00022 21.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS84698.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS84698.1 - 0.019 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CARM1 PF11531.3 ETS84698.1 - 0.025 14.3 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal NB-ARC PF00931.17 ETS84698.1 - 0.037 12.8 0.0 0.084 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 ETS84698.1 - 0.069 12.1 0.1 0.54 9.1 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 ETS84698.1 - 0.086 13.1 0.0 0.54 10.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain RbsD_FucU PF05025.8 ETS84698.1 - 0.11 12.8 0.5 0.31 11.3 0.3 1.7 1 0 0 1 1 1 0 RbsD / FucU transport protein family GMC_oxred_N PF00732.14 ETS84699.1 - 2.6e-53 181.1 0.0 3.7e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS84699.1 - 2.5e-32 112.1 0.0 5.9e-32 110.9 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS84699.1 - 5e-07 28.9 0.0 1.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS84699.1 - 2.2e-05 23.5 0.2 0.003 16.4 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS84699.1 - 0.00015 21.7 0.5 0.00037 20.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS84699.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS84699.1 - 0.0015 18.4 0.1 0.0049 16.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS84699.1 - 0.02 14.9 0.3 0.22 11.5 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS84699.1 - 0.027 12.9 0.2 0.19 10.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 ETS84699.1 - 0.044 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 ETS84699.1 - 0.097 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain UCR_TM PF02921.9 ETS84699.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region GIDA PF01134.17 ETS84699.1 - 0.22 10.3 0.0 0.43 9.3 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 ETS84700.1 - 4e-10 39.8 0.1 1.6e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS84700.1 - 0.0003 20.5 0.0 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 ETS84700.1 - 0.084 11.7 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Sugar_tr PF00083.19 ETS84701.1 - 1.1e-81 274.7 32.6 1.3e-81 274.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS84701.1 - 1.7e-12 46.7 50.5 2.1e-10 39.8 12.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS84701.1 - 6.1e-05 21.5 21.9 0.00031 19.2 5.8 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein EVE PF01878.13 ETS84702.1 - 8.5e-49 165.2 0.0 1.8e-48 164.1 0.0 1.6 1 0 0 1 1 1 1 EVE domain SRP-alpha_N PF04086.8 ETS84702.1 - 2.2 7.5 18.9 2.5 7.4 12.7 1.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal U3_assoc_6 PF08640.6 ETS84703.1 - 1.2e-23 82.6 0.2 5e-23 80.6 0.0 2.1 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 ETS84703.1 - 0.00033 19.6 0.2 0.00091 18.2 0.1 1.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 ETS84703.1 - 0.0021 18.5 0.0 3.8 8.3 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat HAT PF02184.11 ETS84703.1 - 0.027 14.1 0.1 6.7 6.5 0.0 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 ETS84703.1 - 0.049 13.8 0.0 22 5.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Frag1 PF10277.4 ETS84704.1 - 4.3e-41 140.7 11.0 4.3e-41 140.7 7.6 2.8 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Amidase PF01425.16 ETS84705.1 - 4.6e-69 233.3 1.9 4.5e-66 223.5 0.2 2.1 2 0 0 2 2 2 2 Amidase HK PF02110.10 ETS84706.1 - 1.3e-74 250.4 5.4 2.3e-74 249.6 3.8 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 ETS84706.1 - 1.3e-58 197.0 1.3 2.7e-58 196.0 0.9 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 ETS84706.1 - 0.0059 15.9 1.7 0.0059 15.9 1.2 2.0 2 1 0 3 3 3 1 Carbohydrate kinase DUF919 PF06034.6 ETS84707.1 - 0.0056 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) LsmAD PF06741.8 ETS84707.1 - 0.0089 16.1 1.1 0.62 10.2 0.0 2.6 2 0 0 2 2 2 2 LsmAD domain BP28CT PF08146.7 ETS84708.1 - 6.1e-40 136.4 0.0 3.1e-39 134.1 0.0 2.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 ETS84708.1 - 7.3e-23 80.8 0.3 7.3e-23 80.8 0.2 5.2 4 1 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 ETS84708.1 - 6.8e-05 22.6 6.4 0.075 13.1 0.1 5.4 4 0 0 4 4 4 2 HEAT repeat V-ATPase_H_N PF03224.9 ETS84708.1 - 0.0054 15.9 8.0 0.2 10.7 0.6 3.7 3 1 0 3 3 3 2 V-ATPase subunit H HEAT_EZ PF13513.1 ETS84708.1 - 9.2 6.9 23.0 19 5.9 0.0 7.9 6 2 1 7 7 7 0 HEAT-like repeat Aminotran_1_2 PF00155.16 ETS84709.1 - 1.4e-80 271.0 0.0 2e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ETS84709.1 - 1.1e-05 24.3 0.0 1.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS84709.1 - 7.7e-05 21.1 0.0 0.00017 20.0 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3405 PF11885.3 ETS84709.1 - 0.0088 14.3 0.0 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF2278 PF10042.4 ETS84710.1 - 1.8e-60 204.1 1.1 2.1e-60 203.9 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Lipase_GDSL_2 PF13472.1 ETS84711.1 - 5e-17 62.5 0.1 6.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS84711.1 - 1.9e-12 47.5 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ETS84711.1 - 0.049 13.3 0.0 0.25 11.0 0.0 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AA_permease PF00324.16 ETS84712.1 - 1.9e-110 369.4 40.8 2.4e-110 369.1 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS84712.1 - 2.5e-33 115.2 46.9 3e-33 114.9 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 ETS84712.1 - 0.0036 16.2 0.0 0.17 10.8 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M50 NmrA PF05368.8 ETS84714.1 - 1.1e-33 116.4 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS84714.1 - 9.3e-11 42.0 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS84714.1 - 7.8e-05 22.6 0.3 0.00012 21.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS84714.1 - 0.00089 18.7 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS84714.1 - 0.00097 18.1 0.1 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 ETS84714.1 - 0.0011 18.6 0.2 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS84714.1 - 0.0041 15.8 0.0 0.0065 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPRTase PF14681.1 ETS84714.1 - 0.056 12.6 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Formyl_trans_N PF00551.14 ETS84714.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase SnoaL PF07366.7 ETS84715.1 - 0.00063 19.3 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 ETS84715.1 - 0.085 13.2 0.0 0.1 12.9 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain DUF1772 PF08592.6 ETS84716.1 - 8.3e-15 54.7 0.5 9.8e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) p450 PF00067.17 ETS84717.1 - 8.7e-50 169.5 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 ETS84718.1 - 1.1e-17 64.1 0.6 7.5e-16 58.1 0.4 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS84718.1 - 7.1e-09 35.0 0.7 1.6e-06 27.2 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS84718.1 - 2e-08 33.1 0.5 0.00078 18.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 ETS84718.1 - 2.6e-08 33.1 0.2 9.4e-08 31.3 0.1 1.8 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS84718.1 - 6.7e-08 32.6 0.1 2.7e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS84718.1 - 1.5e-05 25.2 0.1 4.9e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84718.1 - 3.3e-05 23.8 0.1 7.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS84718.1 - 4.9e-05 22.5 0.1 0.00022 20.4 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS84718.1 - 7.7e-05 23.0 0.5 0.039 14.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS84718.1 - 0.00057 19.4 0.0 0.0022 17.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 ETS84718.1 - 0.0011 17.9 0.2 0.0049 15.7 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 ETS84718.1 - 0.0057 15.7 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 ETS84718.1 - 0.019 13.6 0.2 3 6.3 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_10 PF13460.1 ETS84718.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Lycopene_cycl PF05834.7 ETS84718.1 - 0.07 12.0 0.1 0.88 8.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 ETS84718.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transp_cyt_pur PF02133.10 ETS84719.1 - 1.1e-101 340.5 38.2 1.4e-101 340.1 26.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 ETS84720.1 - 4.1e-25 88.5 0.0 7.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS84720.1 - 6.2e-22 77.7 0.0 1.1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 ETS84721.1 - 6.7e-75 252.6 0.5 9.1e-75 252.1 0.4 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 ETS84721.1 - 6.5e-42 143.4 0.0 1.2e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Ricin_B_lectin PF00652.17 ETS84722.1 - 2.5e-10 40.4 0.6 6.7e-07 29.3 0.1 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Peptidase_M14 PF00246.19 ETS84723.1 - 5.9e-64 216.3 0.1 7.4e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase SnoaL_4 PF13577.1 ETS84724.1 - 8.5e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DnaJ_CXXCXGXG PF00684.14 ETS84725.1 - 9.2e-13 48.0 67.6 0.0017 18.3 4.4 6.2 1 1 5 6 6 6 6 DnaJ central domain zinc-ribbons_6 PF07191.7 ETS84725.1 - 0.0083 15.8 56.7 0.29 10.9 5.3 5.5 2 1 4 6 6 6 5 zinc-ribbons DUF3773 PF12608.3 ETS84725.1 - 0.32 11.0 6.7 7.7 6.6 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3773) SerH PF06873.6 ETS84725.1 - 2.9 6.4 46.9 9.5 4.7 9.1 3.7 1 1 2 3 3 3 0 Cell surface immobilisation antigen SerH DUF1272 PF06906.6 ETS84725.1 - 4.9 7.0 49.9 1.6 8.6 2.5 8.4 1 1 9 10 10 10 0 Protein of unknown function (DUF1272) DUF4471 PF14740.1 ETS84725.1 - 5.2 6.2 11.5 3.6 6.7 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4471) FMO-like PF00743.14 ETS84726.1 - 2.7e-32 111.6 0.0 1.2e-16 59.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS84726.1 - 4e-20 72.7 0.0 1.1e-18 68.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS84726.1 - 9e-10 37.9 0.1 2.2e-07 30.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS84726.1 - 1e-08 35.3 0.0 6.5e-06 26.1 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS84726.1 - 6.6e-06 25.9 2.7 0.00033 20.4 0.6 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS84726.1 - 7.1e-06 25.9 0.2 6e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS84726.1 - 0.00077 18.4 4.8 2 7.2 0.3 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 ETS84726.1 - 0.0013 17.8 0.7 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Methyltransf_18 PF12847.2 ETS84726.1 - 0.058 13.9 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DJ-1_PfpI PF01965.19 ETS84726.1 - 0.064 12.7 0.0 2.5 7.5 0.0 2.6 3 0 0 3 3 3 0 DJ-1/PfpI family Pyr_redox PF00070.22 ETS84726.1 - 0.27 11.6 2.6 9.4 6.7 0.1 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_10 PF00331.15 ETS84727.1 - 4.7e-98 328.1 0.0 5.8e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sporozoite_P67 PF05642.6 ETS84727.1 - 2 6.1 18.0 7.7 4.2 12.5 1.9 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Arrestin_C PF02752.17 ETS84728.1 - 2.2e-17 63.4 0.0 1.1e-16 61.1 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 ETS84728.1 - 4.9e-08 32.9 0.4 0.002 17.9 0.0 2.5 1 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Dehydratase_hem PF13816.1 ETS84729.1 - 2.1e-113 378.4 0.0 2.4e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 ETS84729.1 - 2.3e-07 30.8 0.0 0.0079 16.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ABM PF03992.11 ETS84729.1 - 9.1e-05 22.4 0.3 0.00022 21.1 0.2 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.13 ETS84730.1 - 1.1e-12 47.4 1.6 1.1e-12 47.4 1.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 ETS84731.1 - 1.8e-31 108.9 0.0 2.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 ETS84732.1 - 1.8e-42 145.3 36.8 1.8e-42 145.3 25.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84732.1 - 9.5e-14 50.8 11.0 9.5e-14 50.8 7.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter PilJ PF13675.1 ETS84733.1 - 0.0016 18.7 4.2 0.0059 16.9 0.2 2.7 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term MutS_III PF05192.13 ETS84733.1 - 0.02 14.6 3.8 0.1 12.3 2.6 2.2 1 1 0 1 1 1 0 MutS domain III Hce2 PF14856.1 ETS84733.1 - 0.13 12.1 0.1 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor Glyco_hydro_32N PF00251.15 ETS84734.1 - 2.6e-15 56.6 0.2 4e-14 52.6 0.1 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 ETS84734.1 - 1.1e-05 25.7 0.1 3.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Abhydrolase_6 PF12697.2 ETS84735.1 - 1.4e-32 113.3 1.4 2.5e-32 112.6 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84735.1 - 1.6e-18 67.0 0.6 4.9e-15 55.7 0.2 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84735.1 - 1.4e-17 63.8 0.8 2.4e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS84735.1 - 2.2e-06 27.4 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 ETS84735.1 - 2.5e-05 22.9 0.0 3.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 ETS84735.1 - 0.001 18.7 0.2 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.7 ETS84735.1 - 0.0034 16.2 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 ETS84735.1 - 0.013 15.0 0.1 0.08 12.5 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 ETS84735.1 - 0.019 14.5 0.0 0.7 9.4 0.0 2.2 1 1 1 2 2 2 0 Serine hydrolase Esterase PF00756.15 ETS84735.1 - 0.051 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 ETS84735.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain AAA PF00004.24 ETS84738.1 - 3e-17 63.0 0.0 6.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS84738.1 - 0.00018 21.2 0.0 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS84738.1 - 0.00066 19.8 0.1 0.0025 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS84738.1 - 0.002 17.8 0.1 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS84738.1 - 0.0032 18.2 0.4 0.016 16.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS84738.1 - 0.0057 16.5 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS84738.1 - 0.0058 16.6 0.2 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 ETS84738.1 - 0.014 15.6 0.0 0.049 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS84738.1 - 0.061 13.2 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 ETS84738.1 - 0.08 12.5 1.4 0.54 9.9 0.0 2.5 2 1 0 2 2 2 0 NACHT domain PsbH PF00737.15 ETS84740.1 - 0.095 12.2 6.5 0.73 9.4 1.5 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein PTR2 PF00854.16 ETS84741.1 - 1.4e-25 89.9 0.0 1.7e-23 82.9 0.0 2.3 1 1 0 1 1 1 1 POT family ATPase_gene1 PF09527.5 ETS84741.1 - 0.036 13.8 0.5 0.036 13.8 0.3 3.7 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit (ATPase_gene1) Steroid_dh PF02544.11 ETS84742.1 - 5.3e-22 78.2 1.4 5.3e-22 78.2 1.0 2.4 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 ETS84742.1 - 2.6e-05 23.6 2.0 4.3e-05 22.9 1.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF544 PF04424.8 ETS84743.1 - 4.5e-14 52.2 0.0 7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) COesterase PF00135.23 ETS84744.1 - 7.1e-106 355.0 0.0 9e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS84744.1 - 2.8e-05 23.7 0.1 0.00018 21.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B PF00753.22 ETS84745.1 - 1e-23 83.9 3.5 1.5e-23 83.4 2.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS84745.1 - 1.1e-06 28.2 0.1 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS84745.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DEC-1_C PF04626.8 ETS84745.1 - 0.044 13.9 0.2 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Aa_trans PF01490.13 ETS84746.1 - 9.4e-42 142.9 40.5 1.2e-41 142.6 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HET PF06985.6 ETS84747.1 - 9.5e-30 103.5 0.1 1.6e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPT6_acidic PF14632.1 ETS84748.1 - 0.33 11.1 8.2 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Cut8_N PF14482.1 ETS84748.1 - 4.7 7.2 5.9 0.71 9.9 1.1 1.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Isochorismatase PF00857.15 ETS84749.1 - 9.4e-19 67.9 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family PIF1 PF05970.9 ETS84750.1 - 1.6e-35 122.7 0.1 3.9e-24 85.2 0.0 3.4 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 ETS84750.1 - 4e-18 65.7 0.0 4.8e-15 55.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.9 ETS84750.1 - 1.5e-07 29.6 0.1 3.7e-06 25.0 0.0 2.5 3 0 0 3 3 3 1 Helicase Viral_helicase1 PF01443.13 ETS84750.1 - 9.1e-07 28.6 2.9 0.074 12.5 0.3 3.7 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 ETS84750.1 - 3.5e-05 23.4 0.2 0.00013 21.6 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain UvrD_C_2 PF13538.1 ETS84750.1 - 4.7e-05 23.4 0.0 9.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ArgK PF03308.11 ETS84750.1 - 0.00019 20.3 0.1 0.00032 19.5 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_5 PF07728.9 ETS84750.1 - 0.00021 21.0 0.1 0.001 18.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS84750.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS84750.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 ETS84750.1 - 0.0032 17.1 0.5 0.097 12.3 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA PF00004.24 ETS84750.1 - 0.0035 17.5 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETS84750.1 - 0.0063 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 ETS84750.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 ETS84750.1 - 0.0082 15.8 0.1 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 ETS84750.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS84750.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 ETS84750.1 - 0.021 14.3 0.2 0.12 11.8 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 ETS84750.1 - 0.026 13.7 0.0 0.37 10.0 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein TrwB_AAD_bind PF10412.4 ETS84750.1 - 0.035 12.7 0.1 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 ETS84750.1 - 0.041 13.5 0.4 0.32 10.6 0.3 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 ETS84750.1 - 0.062 12.7 0.5 0.18 11.1 0.1 1.8 1 1 1 2 2 2 0 AAA-like domain DUF815 PF05673.8 ETS84750.1 - 0.071 12.0 0.1 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 ETS84750.1 - 0.072 13.2 0.3 0.5 10.5 0.2 2.4 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.9 ETS84750.1 - 0.073 12.7 0.2 0.26 10.9 0.1 1.9 1 1 0 1 1 1 0 Helicase PRK PF00485.13 ETS84750.1 - 0.13 11.8 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 ETS84750.1 - 0.41 10.2 1.1 7.3 6.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 c-SKI_SMAD_bind PF08782.5 ETS84750.1 - 8.2 6.6 8.2 0.66 10.1 1.6 2.1 3 0 0 3 3 1 0 c-SKI Smad4 binding domain AMP-binding PF00501.23 ETS84751.1 - 4.9e-84 282.1 0.0 8.4e-84 281.3 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme 2OG-FeII_Oxy_3 PF13640.1 ETS84754.1 - 3.5e-11 43.4 0.1 8.8e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETS84754.1 - 2.1e-06 27.2 0.6 5.7e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 ETS84755.1 - 2.5e-20 73.0 0.2 9.1e-17 61.5 0.3 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NDUFA12 PF05071.11 ETS84757.1 - 5.3e-11 42.9 0.6 5.3e-11 42.9 0.4 2.1 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 ETS84758.1 - 4.6e-08 33.0 0.0 7.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Acetyltransf_1 PF00583.19 ETS84759.1 - 0.1 12.6 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF4451 PF14616.1 ETS84760.1 - 2.9e-35 120.7 0.4 5.5e-35 119.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF605 PF04652.11 ETS84761.1 - 7.9 5.7 33.7 12 5.1 23.3 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 ETS84761.1 - 9.9 4.2 19.9 12 3.9 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_4 PF12799.2 ETS84762.1 - 0.0027 17.2 19.5 0.23 11.1 0.1 6.4 5 2 0 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 ETS84762.1 - 0.01 15.5 2.4 0.038 13.7 0.5 2.5 1 1 1 2 2 2 0 F-box-like LRR_8 PF13855.1 ETS84762.1 - 0.024 14.3 15.0 0.41 10.4 0.0 5.5 4 2 1 5 5 5 0 Leucine rich repeat Rad9 PF04139.8 ETS84763.1 - 1.7e-66 223.9 0.5 2e-66 223.7 0.4 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 ETS84763.1 - 0.0031 16.3 1.7 0.028 13.1 1.1 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 ETS84763.1 - 0.034 13.1 0.0 0.11 11.4 0.0 1.8 2 1 0 2 2 2 0 Hus1-like protein RCC1 PF00415.13 ETS84764.1 - 4.6e-32 109.9 30.1 9.7e-10 38.5 0.0 7.8 6 3 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 ETS84764.1 - 2e-21 75.0 34.5 1.9e-07 30.4 0.8 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.12 ETS84765.1 - 9.2e-16 57.4 0.0 1.3e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 ETS84765.1 - 4e-07 30.0 0.0 8.2e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 ETS84765.1 - 6.9e-06 26.4 0.0 3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 ETS84765.1 - 1.1e-05 24.8 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 ETS84765.1 - 6.1e-05 22.2 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS84765.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 ETS84765.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 ETS84765.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Carb_anhydrase PF00194.16 ETS84766.1 - 2.8e-17 62.5 0.0 4.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Ribosomal_L24e PF01246.15 ETS84767.1 - 3.9e-30 103.5 0.3 3.9e-30 103.5 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e Kei1 PF08552.6 ETS84767.1 - 0.12 11.9 1.2 0.16 11.6 0.8 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 A_deamin PF02137.13 ETS84768.1 - 5.6e-59 200.1 0.0 9.4e-59 199.4 0.0 1.3 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.13 ETS84769.1 - 4e-20 71.0 0.1 6.4e-20 70.4 0.1 1.3 1 0 0 1 1 1 1 NAC domain RdRP PF05183.7 ETS84770.1 - 3.5e-176 587.3 0.0 6.1e-176 586.5 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 ETS84770.1 - 1.2e-07 31.5 0.0 2e-05 24.4 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS84770.1 - 0.0075 15.8 0.0 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 ETS84771.1 - 1e-61 208.4 0.1 2e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS84771.1 - 1.2e-35 122.0 0.0 2.3e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 ETS84771.1 - 0.073 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ribosomal_S4e PF00900.15 ETS84772.1 - 8e-32 108.7 0.3 1.6e-31 107.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 ETS84772.1 - 2.4e-18 65.7 4.3 4.9e-18 64.6 3.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 ETS84772.1 - 0.00024 20.6 5.6 0.00024 20.6 3.9 3.2 4 0 0 4 4 4 1 KOW motif S4 PF01479.20 ETS84772.1 - 0.0004 19.7 0.0 0.00075 18.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Myb_DNA-binding PF00249.26 ETS84773.1 - 2.1e-12 46.8 0.7 4.3e-06 26.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS84773.1 - 2.2e-12 46.9 0.7 6.8e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CHDCT2 PF08074.6 ETS84773.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain SLIDE PF09111.5 ETS84773.1 - 0.074 12.7 0.3 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 SLIDE bZIP_1 PF00170.16 ETS84775.1 - 3.4e-10 39.7 13.8 6.3e-10 38.8 9.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS84775.1 - 0.012 15.4 14.0 0.012 15.4 9.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 ETS84775.1 - 0.014 15.7 0.3 0.043 14.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 ETS84775.1 - 0.022 14.2 3.6 0.05 13.0 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 ETS84775.1 - 0.06 13.6 14.6 0.057 13.7 9.0 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor NAM-associated PF14303.1 ETS84775.1 - 0.07 13.4 10.4 0.11 12.8 7.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CCDC155 PF14662.1 ETS84775.1 - 0.092 12.3 8.8 0.14 11.7 6.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 ETS84775.1 - 0.34 8.7 1.0 0.4 8.4 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF966 PF06136.8 ETS84775.1 - 0.41 10.0 10.4 0.58 9.5 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LMSTEN PF07988.7 ETS84775.1 - 0.95 8.8 5.2 5.8 6.2 0.1 2.8 1 1 1 2 2 2 0 LMSTEN motif CDC45 PF02724.9 ETS84775.1 - 1.6 6.6 9.1 2.1 6.2 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Neisseria_TspB PF05616.8 ETS84775.1 - 1.7 6.9 9.4 2.3 6.4 6.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TFIIA PF03153.8 ETS84775.1 - 3 7.6 17.0 3.6 7.3 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1003 PF06210.6 ETS84775.1 - 4 7.4 5.1 8 6.4 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Spore_coat_CotO PF14153.1 ETS84775.1 - 8 5.8 10.6 13 5.1 7.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO FTR1 PF03239.9 ETS84778.1 - 0.031 13.2 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family DUF2730 PF10805.3 ETS84778.1 - 0.084 12.6 0.3 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1151 PF06625.6 ETS84778.1 - 0.22 11.2 4.9 0.28 10.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) His_Phos_1 PF00300.17 ETS84780.1 - 1.9e-31 109.3 0.0 2.2e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RuBisCO_small PF00101.15 ETS84780.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Zn_clus PF00172.13 ETS84782.1 - 2.8e-08 33.5 7.6 4.1e-08 32.9 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 ETS84783.1 - 1.1e-15 57.6 0.1 2.4e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84783.1 - 2.3e-12 47.4 0.2 6.1e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS84783.1 - 8.2e-11 42.2 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS84783.1 - 1.4e-10 41.5 0.0 3.7e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS84783.1 - 2e-09 37.2 0.0 6.7e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS84783.1 - 3e-08 33.9 0.0 3.3e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS84783.1 - 8.2e-05 21.8 0.0 0.00024 20.2 0.0 1.7 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS84783.1 - 0.00037 20.5 0.1 0.002 18.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Nucleoplasmin PF03066.10 ETS84783.1 - 0.00061 19.3 1.2 0.001 18.5 0.8 1.3 1 0 0 1 1 1 1 Nucleoplasmin Methyltransf_32 PF13679.1 ETS84783.1 - 0.0073 15.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 ETS84783.1 - 0.091 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 ETS84783.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase YvrJ PF12841.2 ETS84783.1 - 0.19 11.0 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family Nop14 PF04147.7 ETS84783.1 - 0.21 9.4 1.8 0.28 9.0 1.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 ETS84783.1 - 4 6.6 7.6 5.5 6.1 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein GAT PF03127.9 ETS84784.1 - 6e-16 58.2 2.6 1.8e-15 56.7 0.2 2.2 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 ETS84784.1 - 2.7e-05 23.8 0.0 7.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 VHS domain MFS_1 PF07690.11 ETS84785.1 - 8.6e-23 80.6 31.1 3.6e-12 45.6 2.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS84785.1 - 3.8e-06 25.5 20.6 0.0014 17.1 7.1 2.8 1 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 ETS84785.1 - 0.00064 18.4 14.9 0.0013 17.4 2.6 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 ETS84785.1 - 0.0067 16.2 2.1 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 MFS_1 like family CorA PF01544.13 ETS84786.1 - 1.1e-06 27.9 2.2 1.3e-06 27.7 0.8 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acyl_transf_3 PF01757.17 ETS84787.1 - 6.8e-23 81.0 21.9 6.8e-23 81.0 15.2 1.6 2 0 0 2 2 2 1 Acyltransferase family SET PF00856.23 ETS84788.1 - 5.7e-20 72.2 0.3 5.7e-20 72.2 0.2 2.4 3 0 0 3 3 3 1 SET domain dCMP_cyt_deam_1 PF00383.17 ETS84789.1 - 4e-20 71.3 0.0 9.6e-20 70.1 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 ETS84789.1 - 0.0016 18.2 1.1 0.021 14.7 0.8 2.5 1 1 0 1 1 1 1 Bd3614-like deaminase Zn_clus PF00172.13 ETS84790.1 - 0.98 9.3 9.7 1.7 8.6 6.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sina PF03145.11 ETS84791.1 - 0.034 13.8 1.7 0.059 13.0 1.2 1.4 1 0 0 1 1 1 0 Seven in absentia protein family DUF2439 PF10382.4 ETS84792.1 - 1.9e-25 88.8 0.1 4.1e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) BAR PF03114.13 ETS84793.1 - 2.1e-14 53.6 0.2 3.7e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 ETS84793.1 - 2.6e-13 49.1 0.3 5.4e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 ETS84793.1 - 4.9e-13 48.4 0.0 1.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 ETS84793.1 - 1.1e-09 37.6 0.0 2.4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MARVEL PF01284.18 ETS84795.1 - 7.3e-06 25.8 13.9 7.2e-05 22.6 7.2 2.2 2 0 0 2 2 2 2 Membrane-associating domain FA_desaturase PF00487.19 ETS84795.1 - 9.7 5.5 14.9 6.1 6.1 6.6 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Response_reg PF00072.19 ETS84796.1 - 3.9e-20 71.9 0.0 2.3e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.3 ETS84797.1 - 4.1e-49 166.8 1.1 4.1e-49 166.8 0.8 1.7 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.1 ETS84798.1 - 1.6e-45 155.3 0.0 2.9e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 ETS84798.1 - 2.1e-05 24.5 0.0 6.6e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 ETS84798.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 ETS84798.1 - 0.0061 15.9 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF4266 PF14086.1 ETS84799.1 - 0.25 11.8 2.9 0.23 11.9 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4266) PhnA_Zn_Ribbon PF08274.7 ETS84799.1 - 1.4 8.7 4.7 4.3 7.2 0.5 2.6 2 1 0 2 2 2 0 PhnA Zinc-Ribbon LSM PF01423.17 ETS84800.1 - 3.6e-16 58.4 0.1 4.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Zn_clus PF00172.13 ETS84801.1 - 0.014 15.2 10.7 0.026 14.4 7.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 ETS84802.1 - 0.00018 20.7 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 ETS84803.1 - 2.9e-10 39.4 0.0 6.5e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 ETS84803.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.9 ETS84803.1 - 0.047 12.5 0.5 0.071 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WPP PF13943.1 ETS84803.1 - 6 7.1 15.6 0.14 12.3 0.4 2.8 2 1 1 3 3 3 0 WPP domain PRP21_like_P PF12230.3 ETS84804.1 - 3.2e-55 187.1 16.4 3.2e-55 187.1 11.4 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 ETS84804.1 - 1.2e-40 136.8 0.9 8.6e-20 70.1 0.0 2.6 2 0 0 2 2 2 2 Surp module PMT PF02366.13 ETS84805.1 - 1.8e-75 253.4 16.5 1.8e-75 253.4 11.4 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS84805.1 - 2.6e-55 186.9 0.0 4e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 MIR domain Pkinase PF00069.20 ETS84806.1 - 6.2e-56 189.4 0.0 8.8e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS84806.1 - 2.7e-25 88.9 0.1 1.4e-24 86.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Transglut_N PF00868.15 ETS84806.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.9 1 0 0 1 1 1 0 Transglutaminase family BNR PF02012.15 ETS84807.1 - 0.0014 18.1 3.7 1.6 8.8 0.1 3.7 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_2 PF13088.1 ETS84807.1 - 0.0015 17.9 0.1 0.044 13.0 0.0 2.2 1 1 0 1 1 1 1 BNR repeat-like domain Abhydrolase_6 PF12697.2 ETS84808.1 - 1.5e-15 57.7 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS84808.1 - 4.8e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 ETS84808.1 - 0.0089 14.9 0.0 0.032 13.1 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Ank_2 PF12796.2 ETS84809.1 - 1.2e-41 140.9 20.9 1.5e-14 54.1 0.8 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84809.1 - 3.5e-25 86.5 15.1 9.2e-05 22.0 0.0 9.0 9 0 0 9 9 8 6 Ankyrin repeat Ank_4 PF13637.1 ETS84809.1 - 1.2e-22 79.8 8.9 4.7e-08 33.3 0.0 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84809.1 - 7.7e-17 60.9 11.6 0.00075 19.6 0.0 7.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84809.1 - 3.8e-16 57.5 6.6 0.029 14.5 0.0 8.3 9 0 0 9 9 7 4 Ankyrin repeat AAA_16 PF13191.1 ETS84809.1 - 3.1e-10 40.3 0.3 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS84809.1 - 2.9e-06 27.4 0.0 2.5e-05 24.4 0.0 2.6 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 ETS84809.1 - 1e-05 25.2 0.1 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 ETS84809.1 - 0.0042 15.9 0.1 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 ETS84809.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Filo_VP24 PF06389.6 ETS84809.1 - 0.077 12.2 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 AAA_14 PF13173.1 ETS84809.1 - 0.088 12.7 0.0 0.85 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 ETS84810.1 - 1.9e-16 59.7 0.5 3.6e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain K-box PF01486.12 ETS84810.1 - 1.3 8.8 3.6 0.67 9.7 0.6 1.8 2 0 0 2 2 2 0 K-box region Cupin_1 PF00190.17 ETS84811.1 - 4.8e-08 32.5 0.0 7.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ETS84811.1 - 7.3e-07 28.6 1.1 4.3e-06 26.1 0.8 2.1 1 1 0 1 1 1 1 Cupin domain GMC_oxred_C PF05199.8 ETS84811.1 - 0.0025 18.1 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Cupin_3 PF05899.7 ETS84811.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GPI PF06560.6 ETS84811.1 - 0.094 11.7 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AA_permease PF00324.16 ETS84812.1 - 1.3e-66 224.8 45.2 1.7e-66 224.5 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS84812.1 - 1.5e-24 86.3 50.1 2e-24 85.9 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 ETS84813.1 - 1.5e-19 70.8 0.0 2.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS84813.1 - 2.6e-12 45.7 0.0 7.6e-12 44.1 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS84813.1 - 1.4e-10 41.0 0.0 2.6e-09 36.9 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS84813.1 - 5.1e-08 33.0 0.0 1.3e-05 25.1 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS84813.1 - 1.8e-06 27.0 0.1 2.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS84813.1 - 8.9e-05 22.3 1.0 0.11 12.2 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS84813.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 ETS84813.1 - 0.0087 15.0 0.0 1.2 7.9 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS84813.1 - 0.015 15.6 0.0 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Agglutinin PF07468.6 ETS84814.1 - 0.08 12.9 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Agglutinin Ank_2 PF12796.2 ETS84815.1 - 4.4e-34 116.6 0.5 3.3e-13 49.7 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84815.1 - 7.4e-28 94.9 0.1 2e-05 24.1 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 ETS84815.1 - 1.8e-22 79.2 0.3 3.1e-07 30.7 0.0 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS84815.1 - 2e-17 62.7 0.5 2.3e-06 27.6 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84815.1 - 2.5e-15 55.0 0.4 0.034 14.3 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat AAA_16 PF13191.1 ETS84815.1 - 8.1e-10 38.9 0.2 2.8e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ETS84815.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS84815.1 - 2e-05 24.7 0.0 8.2e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 ETS84815.1 - 0.0084 16.3 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS84815.1 - 0.018 13.8 0.0 0.047 12.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 ETS84815.1 - 0.028 14.1 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 ETS84815.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 ETS84815.1 - 0.077 12.8 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_12 PF13424.1 ETS84815.1 - 0.083 12.8 1.5 0.41 10.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CbiA PF01656.18 ETS84815.1 - 0.18 11.1 0.0 0.65 9.3 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Macro PF01661.16 ETS84816.1 - 7.3e-24 83.9 0.0 1.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Macro domain Abhydrolase_3 PF07859.8 ETS84817.1 - 5.6e-15 55.4 0.0 9.5e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84817.1 - 4.7e-12 45.8 0.0 1.3e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETS84817.1 - 1.1e-10 40.9 0.0 1.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 ETS84817.1 - 2.5e-09 36.6 0.0 0.00076 18.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 ETS84817.1 - 7e-09 34.9 0.0 9.1e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 ETS84817.1 - 4.3e-08 33.3 0.0 7.3e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS84817.1 - 5.3e-06 26.0 0.0 1e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 ETS84817.1 - 1.8e-05 23.7 0.0 2.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.15 ETS84817.1 - 0.00059 19.4 0.0 0.077 12.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 ETS84817.1 - 0.0013 17.3 0.2 0.36 9.2 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 ETS84817.1 - 0.0049 16.3 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase S1_2 PF13509.1 ETS84817.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 S1 domain MFS_1 PF07690.11 ETS84818.1 - 3.9e-31 108.0 24.6 3.9e-31 108.0 17.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84818.1 - 5.7e-13 48.2 29.5 1.1e-11 43.9 7.3 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter Beach PF02138.13 ETS84821.1 - 2.6e-108 361.5 0.0 4.4e-108 360.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 ETS84821.1 - 1.1e-13 50.8 0.0 3.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 ETS84821.1 - 1.4e-10 41.6 0.0 3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 ETS84821.1 - 4.7e-08 32.6 6.2 0.0058 16.4 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat DDOST_48kD PF03345.9 ETS84823.1 - 2.5e-167 556.6 0.0 2.8e-167 556.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Peptidase_S8 PF00082.17 ETS84824.1 - 5.8e-50 170.0 10.7 8.6e-50 169.4 7.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 ETS84824.1 - 1.6e-19 70.2 1.0 3.7e-19 69.0 0.7 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S15 PF02129.13 ETS84826.1 - 1.9e-38 132.4 0.7 4.4e-34 118.1 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS84826.1 - 5.7e-29 101.5 0.0 8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS84826.1 - 2.4e-06 27.5 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS84826.1 - 0.025 14.4 0.1 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PhyH PF05721.8 ETS84827.1 - 7e-07 29.4 0.0 1.3e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS84827.1 - 0.0019 16.7 0.0 0.094 11.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 ETS84827.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Fungal_trans PF04082.13 ETS84828.1 - 5.2e-15 55.0 0.3 9.1e-15 54.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84828.1 - 1.2e-08 34.6 9.1 2e-08 33.9 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dopey_N PF04118.9 ETS84828.1 - 0.16 10.6 0.3 0.51 9.0 0.2 1.8 1 1 0 1 1 1 0 Dopey, N-terminal MFS_1 PF07690.11 ETS84829.1 - 4e-19 68.5 17.0 4e-19 68.5 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84829.1 - 0.00014 20.5 19.1 0.00014 20.5 13.2 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter AAL_decarboxy PF03306.8 ETS84830.1 - 0.044 12.8 1.1 0.048 12.6 0.0 1.5 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase Dicty_REP PF05086.7 ETS84830.1 - 0.11 10.1 3.4 0.15 9.7 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_S27e PF01667.12 ETS84831.1 - 3.4e-28 96.9 7.4 4.7e-28 96.4 5.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 ETS84831.1 - 0.014 15.2 1.4 0.017 14.9 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 ETS84831.1 - 0.43 9.9 3.3 0.61 9.4 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 ETS84832.1 - 4.4e-13 48.5 0.3 6.6e-13 47.9 0.2 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 ETS84832.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF3503 PF12011.3 ETS84832.1 - 0.057 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) U3_assoc_6 PF08640.6 ETS84832.1 - 0.068 12.9 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 DUF3350 PF11830.3 ETS84832.1 - 0.76 9.8 6.7 6.6 6.8 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3350) LRR_4 PF12799.2 ETS84833.1 - 1.9e-11 43.3 15.9 2.9e-07 29.9 1.4 3.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS84833.1 - 4.7e-07 29.4 4.6 3.1e-06 26.8 0.6 3.2 2 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 ETS84833.1 - 0.00014 21.3 8.2 1.8 8.8 0.0 5.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 ETS84833.1 - 0.11 12.6 2.4 16 5.9 0.2 3.7 3 1 1 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 ETS84833.1 - 0.42 11.0 10.7 9.4 6.9 0.6 5.3 6 0 0 6 6 6 0 Leucine rich repeat 4HBT PF03061.17 ETS84834.1 - 1.6e-07 31.3 0.2 2.8e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DAP_B PF07930.7 ETS84834.1 - 0.0029 17.3 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 D-aminopeptidase, domain B FAD_binding_3 PF01494.14 ETS84835.1 - 1.8e-73 247.6 0.0 5.7e-73 246.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS84835.1 - 2.9e-24 85.5 0.0 5.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 ETS84835.1 - 3.2e-06 27.0 0.0 3.6e-05 23.6 0.0 2.5 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS84835.1 - 4.9e-05 21.9 0.0 7.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 ETS84835.1 - 6.3e-05 22.0 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS84835.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS84835.1 - 0.00013 20.9 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS84835.1 - 0.00072 18.7 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 ETS84835.1 - 0.0015 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 ETS84835.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS84835.1 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS84835.1 - 0.0036 16.0 0.0 0.0052 15.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 ETS84835.1 - 0.011 14.8 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 ETS84835.1 - 0.041 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS84835.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 ETS84835.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FTR PF01913.13 ETS84835.1 - 0.11 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase CPSase_L_chain PF00289.17 ETS84835.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain SE PF08491.5 ETS84835.1 - 0.12 11.1 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase 2-Hacid_dh_C PF02826.14 ETS84835.1 - 0.13 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_5 PF13857.1 ETS84836.1 - 0.001 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS84836.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Acetyltransf_CG PF14542.1 ETS84836.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RRN3 PF05327.6 ETS84836.1 - 0.057 11.5 2.0 0.076 11.1 1.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ank_4 PF13637.1 ETS84836.1 - 0.072 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84836.1 - 0.077 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Nop14 PF04147.7 ETS84836.1 - 0.17 9.7 19.4 0.23 9.3 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETS84836.1 - 0.27 10.8 9.6 0.55 9.8 6.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 ETS84836.1 - 0.28 9.1 8.5 0.54 8.2 5.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETS84836.1 - 1.4 7.3 13.5 2.1 6.7 9.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF3435 PF11917.3 ETS84837.1 - 8.3e-09 34.6 0.0 1.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Ets PF00178.17 ETS84837.1 - 0.022 14.8 0.5 5.1 7.3 0.0 3.5 3 0 0 3 3 3 0 Ets-domain PLDc_2 PF13091.1 ETS84838.1 - 1.3e-26 92.7 0.0 2.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 ETS84838.1 - 0.0013 18.4 0.4 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1669 PF07894.7 ETS84838.1 - 0.28 10.3 5.4 0.61 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1669) HHV6-IE PF03753.8 ETS84841.1 - 0.086 10.3 0.4 0.1 10.0 0.2 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Rb_C PF08934.5 ETS84842.1 - 0.032 13.8 0.2 0.032 13.8 0.1 2.3 2 1 1 3 3 3 0 Rb C-terminal domain CCDC92 PF14916.1 ETS84842.1 - 0.058 13.0 0.3 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function EST1_DNA_bind PF10373.4 ETS84843.1 - 6.7e-17 61.5 0.1 5e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Rhabdo_matrix PF03397.9 ETS84843.1 - 0.097 12.0 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Rhabdovirus matrix protein Pyridox_oxidase PF01243.15 ETS84844.1 - 3.1e-08 33.4 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RTC PF01137.16 ETS84845.1 - 6.2e-40 136.3 0.0 1e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Phosphodiest PF01663.17 ETS84846.1 - 1.1e-87 294.7 0.5 1.6e-87 294.2 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS84846.1 - 0.0039 16.4 0.2 0.11 11.6 0.0 2.3 1 1 0 2 2 2 1 Sulfatase PBP1_TM PF14812.1 ETS84846.1 - 0.15 12.4 17.8 0.36 11.1 6.0 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3915 PF13054.1 ETS84846.1 - 0.56 10.1 1.9 23 4.9 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) RNR_inhib PF08591.5 ETS84847.1 - 2.6e-22 79.5 0.2 8e-22 77.9 0.2 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor SIP1 PF04938.7 ETS84848.1 - 2.9e-05 23.5 0.0 0.21 10.8 0.0 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pyridoxal_deC PF00282.14 ETS84850.1 - 3.5e-22 78.3 0.0 2.2e-14 52.7 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain LisH PF08513.6 ETS84851.1 - 0.085 12.6 0.6 11 5.9 0.0 3.2 3 0 0 3 3 3 0 LisH AAA PF00004.24 ETS84852.1 - 1.9e-16 60.4 0.0 8.4e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS84852.1 - 0.00072 19.7 0.7 0.02 15.0 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS84852.1 - 0.0025 17.5 0.0 0.0078 15.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS84852.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Torsin PF06309.6 ETS84852.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_17 PF13207.1 ETS84852.1 - 0.013 16.2 3.6 0.017 15.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 ETS84852.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 ETS84852.1 - 0.036 13.4 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 ETS84852.1 - 0.039 13.9 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETS84852.1 - 0.045 13.6 0.3 0.48 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS84852.1 - 0.25 11.6 3.0 0.37 11.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain adh_short PF00106.20 ETS84853.1 - 7.6e-14 51.9 0.9 3.9e-13 49.6 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS84853.1 - 7.2e-07 29.2 0.3 1.4e-06 28.2 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS84853.1 - 0.00015 21.4 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS84853.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SSF PF00474.12 ETS84854.1 - 5.2e-12 45.1 31.2 1.8e-11 43.3 21.6 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family MBA1 PF07961.6 ETS84856.1 - 8.1e-10 37.9 0.0 1.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 ETS84856.1 - 0.0015 18.4 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 Tim44-like domain SUI1 PF01253.17 ETS84857.1 - 3e-29 100.6 5.2 3.9e-29 100.2 3.6 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 AdoMet_MTase PF07757.8 ETS84858.1 - 1.9e-39 134.2 0.0 3.9e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 ETS84858.1 - 0.00011 21.9 0.0 0.0003 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS84858.1 - 0.017 14.7 0.3 0.31 10.7 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 ETS84858.1 - 0.076 13.6 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.15 ETS84859.1 - 1e-114 383.7 2.2 1.3e-114 383.4 1.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 ETS84859.1 - 3.2e-57 192.5 3.6 7.3e-57 191.4 2.5 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 ETS84859.1 - 2.9e-16 59.5 0.3 2.9e-05 24.2 0.0 6.3 3 1 3 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 ETS84859.1 - 0.0013 18.9 0.8 4.6 7.9 0.0 4.4 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.11 ETS84859.1 - 0.039 13.9 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 ETS84859.1 - 0.22 11.6 9.5 1.8 8.8 0.2 5.2 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.1 ETS84859.1 - 2.4 8.7 6.9 1 9.9 0.6 3.2 3 0 0 3 3 3 0 HEAT-like repeat CDP-OH_P_transf PF01066.16 ETS84860.1 - 5.9e-16 58.6 3.4 5.9e-16 58.6 2.3 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3437 PF11919.3 ETS84861.1 - 0.04 13.6 0.2 0.045 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) SUR7 PF06687.7 ETS84862.1 - 5.7e-24 84.8 13.1 7.3e-24 84.5 9.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 ETS84862.1 - 0.0066 16.5 0.3 0.0066 16.5 0.2 1.8 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Saccharop_dh PF03435.13 ETS84863.1 - 4.7e-25 88.3 0.2 7.5e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS84863.1 - 0.041 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS84863.1 - 0.058 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 ETS84863.1 - 0.065 12.4 0.1 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ABC1 PF03109.11 ETS84864.1 - 6.8e-23 80.8 0.0 2e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 ETS84864.1 - 0.00098 18.9 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Septin PF00735.13 ETS84865.1 - 2.2e-34 118.8 0.3 7.4e-12 44.8 0.0 3.1 2 1 1 3 3 3 3 Septin KAP_NTPase PF07693.9 ETS84865.1 - 0.0028 16.7 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 ETS84865.1 - 0.005 16.3 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS84865.1 - 0.0063 16.8 0.7 0.01 16.1 0.5 1.5 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 ETS84865.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.7 2 0 0 2 2 1 0 G-protein alpha subunit Miro PF08477.8 ETS84865.1 - 0.022 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 ETS84865.1 - 0.033 14.9 0.2 0.12 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Nop14 PF04147.7 ETS84865.1 - 0.044 11.7 5.0 0.063 11.1 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_18 PF13238.1 ETS84865.1 - 0.047 13.9 0.1 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS84865.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS84865.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 ETS84865.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 ETS84865.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L21e PF01157.13 ETS84866.1 - 1e-39 134.3 3.7 1e-39 134.3 2.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 ETS84867.1 - 4.1e-29 100.8 1.1 8.9e-29 99.7 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 ETS84867.1 - 4.2e-13 48.4 1.2 4.2e-13 48.4 0.8 2.6 3 0 0 3 3 3 1 S4 domain Slu7 PF11708.3 ETS84868.1 - 2.1e-75 253.5 18.3 2.1e-75 253.5 12.7 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 ETS84868.1 - 0.012 15.2 0.6 0.024 14.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 ETS84869.1 - 3e-96 323.0 0.0 4.4e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 ETS84869.1 - 3.7e-24 85.1 0.8 6.6e-13 48.2 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 ETS84869.1 - 5.2e-18 64.8 5.2 5.2e-18 64.8 3.6 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF2404 PF10296.4 ETS84870.1 - 1.6e-33 114.6 0.0 5.3e-33 113.0 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 ETS84870.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 PH domain COX6A PF02046.10 ETS84871.1 - 4.6e-46 155.4 2.2 4.8e-46 155.4 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.18 ETS84872.1 - 3.3e-15 56.7 0.1 5.4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETS84872.1 - 1.3e-14 53.8 0.0 4.4e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 ETS84872.1 - 0.00028 20.7 0.9 0.00066 19.5 0.6 1.7 1 0 0 1 1 1 1 GRF zinc finger F-box-like PF12937.2 ETS84873.1 - 5.2e-05 22.8 0.5 0.00015 21.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS84873.1 - 0.00012 21.6 0.6 0.0011 18.5 0.1 2.5 3 0 0 3 3 3 1 F-box domain TFIIF_alpha PF05793.7 ETS84874.1 - 0.01 14.2 7.1 0.02 13.3 4.9 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0016 PF01169.14 ETS84875.1 - 1.4e-42 143.7 24.8 4.3e-22 78.0 5.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF718 PF05336.8 ETS84876.1 - 7.4e-34 115.7 0.3 9.4e-34 115.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Thioredoxin PF00085.15 ETS84877.1 - 5.8e-06 25.9 0.0 8.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS84877.1 - 0.078 13.1 0.0 0.59 10.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 ETS84878.1 - 1.1e-36 126.3 35.5 1.1e-36 126.3 19.9 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS84878.1 - 5.5e-13 48.2 4.8 5.5e-13 48.2 3.3 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2348 PF09807.4 ETS84879.1 - 2.4e-07 30.1 0.0 4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 ETS84879.1 - 0.051 12.6 0.0 0.097 11.7 0.0 1.4 2 0 0 2 2 2 0 KaiC Ribosomal_L37e PF01907.14 ETS84880.1 - 4.3e-28 96.8 12.6 6.5e-28 96.2 8.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 ETS84880.1 - 0.0024 17.6 1.9 0.0036 17.0 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 ETS84880.1 - 0.011 14.9 0.7 0.018 14.2 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.9 ETS84880.1 - 0.55 10.2 4.7 19 5.3 3.2 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 ETS84880.1 - 1 8.9 3.5 11 5.6 2.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 ETS84880.1 - 1.3 8.7 5.3 2.1 8.0 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 ETS84880.1 - 2.2 7.7 10.1 1.9 7.9 0.3 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4_2 PF13923.1 ETS84880.1 - 2.8 8.0 5.5 4.5 7.3 3.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L40e PF01020.12 ETS84880.1 - 7.8 6.1 11.0 15 5.2 3.0 2.3 1 1 1 2 2 2 0 Ribosomal L40e family Autophagy_N PF03986.8 ETS84881.1 - 2.8e-47 160.1 0.2 2.8e-47 160.1 0.1 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 ETS84881.1 - 1.5e-22 79.5 0.2 4.1e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 ETS84881.1 - 1.3e-14 52.9 0.4 2.5e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Xan_ur_permease PF00860.15 ETS84882.1 - 5.2e-25 87.7 31.2 1e-24 86.7 19.5 2.4 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 ETS84882.1 - 7.6e-05 21.8 3.2 7.6e-05 21.8 2.2 3.2 2 2 2 4 4 4 2 Sulfate transporter family MFS_1 PF07690.11 ETS84883.1 - 5.9e-11 41.6 5.2 7.4e-11 41.3 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2427 PF10348.4 ETS84883.1 - 0.21 11.1 3.4 0.37 10.3 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MFS_1 PF07690.11 ETS84884.1 - 5.4e-11 41.7 12.4 1.4e-10 40.4 8.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 ETS84884.1 - 0.00063 18.2 4.0 0.0012 17.3 2.8 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein Ifi-6-16 PF06140.8 ETS84884.1 - 6.5 6.6 10.0 0.22 11.3 2.4 2.0 2 0 0 2 2 2 0 Interferon-induced 6-16 family YcxB PF14317.1 ETS84886.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein DUF4544 PF15077.1 ETS84887.1 - 0.034 13.6 1.5 0.037 13.5 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) Metallophos PF00149.23 ETS84888.1 - 5.4e-10 38.9 2.2 1.6e-09 37.4 1.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS84888.1 - 1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2052 PF09747.4 ETS84889.1 - 6.1e-28 97.9 14.2 4e-26 92.0 9.8 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Mito_carr PF00153.22 ETS84891.1 - 2.6e-72 238.6 0.3 2.8e-23 81.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 ETS84892.1 - 4.3e-25 87.6 0.1 5.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 PX domain RRM_6 PF14259.1 ETS84893.1 - 0.00021 21.2 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 ETS84894.1 - 6.9e-57 191.5 9.7 1.3e-32 112.5 1.0 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 ETS84895.1 - 6.8e-54 182.7 0.0 8.9e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS84895.1 - 6.3e-20 71.8 0.0 1.2e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 ETS84895.1 - 2.3e-10 39.7 0.0 4.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.17 ETS84896.1 - 1.7e-20 72.4 0.0 7.6e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS84896.1 - 1.1e-13 50.9 0.0 9.2e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS84896.1 - 3.7e-09 36.2 0.0 6.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1690 PF07956.6 ETS84897.1 - 1.9e-34 118.6 5.0 2.3e-34 118.3 3.5 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF1993 PF09351.5 ETS84897.1 - 0.068 13.0 0.9 0.085 12.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Myosin_head PF00063.16 ETS84897.1 - 0.086 10.8 1.5 0.097 10.6 1.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) KAP_NTPase PF07693.9 ETS84897.1 - 0.095 11.6 0.9 0.12 11.3 0.6 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF4460 PF14687.1 ETS84897.1 - 0.13 11.9 0.7 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Fcf1 PF04900.7 ETS84897.1 - 0.19 11.8 2.3 0.38 10.8 0.2 2.1 1 1 1 2 2 2 0 Fcf1 DUF3708 PF12501.3 ETS84897.1 - 0.3 10.9 2.7 0.41 10.4 1.9 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter RIO1 PF01163.17 ETS84897.1 - 0.31 10.3 2.3 0.36 10.1 1.6 1.1 1 0 0 1 1 1 0 RIO1 family Lzipper-MIP1 PF14389.1 ETS84897.1 - 0.36 10.9 6.0 0.072 13.1 1.4 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 THOC7 PF05615.8 ETS84897.1 - 1.1 9.5 9.6 2.6 8.3 6.7 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 TMF_DNA_bd PF12329.3 ETS84897.1 - 3.4 7.5 11.4 2.6 7.9 4.8 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HrpA_pilin PF09589.5 ETS84897.1 - 3.9 7.9 7.5 12 6.3 5.2 1.8 1 1 0 1 1 1 0 HrpA pilus formation protein Cep57_CLD_2 PF14197.1 ETS84897.1 - 4.5 7.2 13.2 16 5.5 0.6 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 CENP-H PF05837.7 ETS84897.1 - 8.6 6.5 9.6 1.9 8.7 4.0 1.9 2 1 1 3 3 2 0 Centromere protein H (CENP-H) TYW3 PF02676.9 ETS84898.1 - 2.7e-64 216.0 0.0 3.3e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 CBM-like PF14683.1 ETS84899.1 - 2.8e-36 124.6 0.0 5.1e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 ETS84899.1 - 4.7e-21 74.7 0.3 4.7e-21 74.7 0.2 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 ETS84899.1 - 4.8e-07 29.7 1.1 2e-06 27.7 0.3 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 ETS84899.1 - 0.041 13.8 0.1 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF2012 PF09430.5 ETS84899.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) zf-DHHC PF01529.15 ETS84900.1 - 3.1e-39 134.1 0.5 3.1e-39 134.1 0.4 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase SpoVA PF03862.8 ETS84900.1 - 0.019 15.0 0.3 0.041 13.9 0.2 1.4 1 0 0 1 1 1 0 SpoVA protein HAD PF12710.2 ETS84902.1 - 3.5e-17 63.1 0.0 5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS84902.1 - 2.5e-10 41.1 3.4 1.8e-08 35.0 2.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS84902.1 - 4.1e-10 39.6 0.7 6.6e-08 32.4 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS84902.1 - 2.3e-05 24.7 0.0 5.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 ETS84902.1 - 0.0012 17.8 0.1 0.0018 17.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.8 ETS84902.1 - 0.07 12.4 0.6 0.55 9.4 0.0 2.4 2 1 1 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.7 ETS84902.1 - 0.076 12.1 0.0 8.4 5.4 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.2 ETS84902.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 1 0 1 1 1 0 Acid Phosphatase DUF2664 PF10867.3 ETS84903.1 - 0.067 13.8 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Ank_4 PF13637.1 ETS84903.1 - 0.093 13.2 0.0 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Takusan PF04822.8 ETS84903.1 - 7.6 6.3 7.4 1 9.1 1.6 2.2 3 0 0 3 3 3 0 Takusan PAPS_reduct PF01507.14 ETS84904.1 - 3.2e-41 141.0 0.0 4.7e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Fasciclin PF02469.17 ETS84905.1 - 9.2e-40 135.6 2.7 3e-19 69.2 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain HEAT PF02985.17 ETS84906.1 - 2.7e-16 58.0 8.7 0.00093 19.0 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 ETS84906.1 - 1.3e-15 57.4 11.8 1.7e-07 31.4 0.0 7.2 2 1 5 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 ETS84906.1 - 2.7e-13 49.9 13.3 5.5e-09 36.2 0.0 8.5 12 1 1 13 13 13 2 HEAT-like repeat IBN_N PF03810.14 ETS84906.1 - 1.5e-09 37.6 3.6 1e-08 34.9 1.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 ETS84906.1 - 4.5e-05 23.1 2.3 4.4 7.2 0.1 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 ETS84906.1 - 5e-05 22.7 1.5 0.54 9.5 0.0 5.6 4 2 2 6 6 6 1 CLASP N terminal SAICAR_synt PF01259.13 ETS84907.1 - 2e-78 262.9 0.0 2.6e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HMGL-like PF00682.14 ETS84908.1 - 6.7e-66 222.3 0.0 8.9e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 ETS84908.1 - 5.6e-23 81.2 0.0 1.2e-22 80.1 0.0 1.5 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain APH PF01636.18 ETS84910.1 - 9.6e-31 107.3 0.0 1.6e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 ETS84910.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase ATG16 PF08614.6 ETS84911.1 - 0.00053 19.8 2.6 0.0011 18.7 1.8 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 ETS84911.1 - 0.00069 19.3 0.6 0.0014 18.3 0.4 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4653 PF15546.1 ETS84911.1 - 0.0015 17.8 0.2 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) DUF2353 PF09789.4 ETS84911.1 - 0.0023 17.2 1.7 0.0043 16.3 1.2 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 ETS84911.1 - 0.0047 16.5 4.3 0.0094 15.5 3.0 1.5 1 0 0 1 1 1 1 IncA protein DUF4201 PF13870.1 ETS84911.1 - 0.011 15.1 3.4 0.025 14.0 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MAD PF05557.8 ETS84911.1 - 0.013 13.5 2.3 0.019 13.0 1.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Filament PF00038.16 ETS84911.1 - 0.018 14.5 1.1 0.042 13.3 0.8 1.5 1 0 0 1 1 1 0 Intermediate filament protein DUF972 PF06156.8 ETS84911.1 - 0.092 13.1 1.5 0.18 12.1 0.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF972) BBP1_C PF15272.1 ETS84911.1 - 0.16 11.5 4.3 0.4 10.2 2.9 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DivIC PF04977.10 ETS84911.1 - 0.62 9.5 3.0 1.2 8.6 0.5 2.2 1 1 0 2 2 2 0 Septum formation initiator NACHT PF05729.7 ETS84912.1 - 7.2e-14 51.7 0.1 2.9e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 ETS84912.1 - 2.4e-11 43.8 0.0 2.5e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PNP_UDP_1 PF01048.15 ETS84912.1 - 3.8e-08 32.5 0.1 9.6e-08 31.2 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank PF00023.25 ETS84912.1 - 4.5e-08 32.5 0.0 0.0032 17.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA_22 PF13401.1 ETS84912.1 - 4.4e-06 26.8 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS84912.1 - 4.9e-06 26.6 0.0 1.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ETS84912.1 - 0.00066 19.5 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS84912.1 - 0.00086 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase Ank_4 PF13637.1 ETS84912.1 - 0.00097 19.5 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RNA_helicase PF00910.17 ETS84912.1 - 0.0014 18.8 0.2 0.012 15.7 0.0 2.7 3 0 0 3 3 3 1 RNA helicase AAA PF00004.24 ETS84912.1 - 0.0014 18.8 0.1 0.0085 16.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS84912.1 - 0.0017 17.2 0.0 0.0041 16.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Torsin PF06309.6 ETS84912.1 - 0.0025 17.6 0.0 0.009 15.9 0.0 2.0 2 0 0 2 2 1 1 Torsin Ank_5 PF13857.1 ETS84912.1 - 0.0084 16.3 0.3 0.24 11.6 0.0 3.2 2 2 2 4 4 3 2 Ankyrin repeats (many copies) AAA_19 PF13245.1 ETS84912.1 - 0.062 13.0 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 ETS84912.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 ETS84913.1 - 6.1e-11 42.6 0.1 7.7e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS84913.1 - 5.4e-07 29.4 0.8 1.5e-06 27.9 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS84913.1 - 0.0014 18.4 0.0 0.0033 17.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS84913.1 - 0.024 14.0 0.1 0.058 12.8 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DAO PF01266.19 ETS84914.1 - 2.9e-28 98.7 0.2 3.5e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS84914.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS84914.1 - 0.01 15.8 1.1 0.021 14.8 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 ETS84914.1 - 0.015 15.0 0.2 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.19 ETS84914.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 ETS84914.1 - 0.026 13.6 0.1 0.048 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 ETS84914.1 - 0.031 14.5 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 ETS84914.1 - 0.081 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS84914.1 - 0.1 12.0 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.14 ETS84915.1 - 7.7e-20 71.2 8.5 7.7e-20 71.2 5.9 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS84915.1 - 8.3e-18 64.7 0.0 7.2e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS84915.1 - 4.6e-14 52.1 0.0 1.4e-13 50.5 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain ANTH PF07651.11 ETS84916.1 - 7.4e-82 274.2 0.0 7.4e-82 274.2 0.0 3.1 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 ETS84916.1 - 1e-62 210.6 9.1 1e-62 210.6 6.3 4.6 4 2 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 ETS84916.1 - 0.00013 21.7 0.0 0.00051 19.9 0.0 2.1 1 0 0 1 1 1 1 ENTH domain CIA30 PF08547.7 ETS84917.1 - 1.2e-43 148.7 0.0 1.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 ETS84918.1 - 8.6e-34 115.2 11.9 1.4e-33 114.6 3.8 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 ETS84918.1 - 0.00024 21.4 8.0 5.7 7.8 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS84918.1 - 0.00088 18.8 0.2 24 5.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS84918.1 - 0.0091 15.5 0.4 17 5.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 ETS84918.1 - 0.035 14.4 10.5 1.7 9.0 0.4 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS84918.1 - 0.036 14.0 10.0 2.6 8.0 0.0 5.9 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS84918.1 - 0.2 12.2 3.7 1 9.9 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SOG2 PF10428.4 ETS84920.1 - 0.23 10.1 6.1 0.27 9.8 4.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.8 ETS84920.1 - 1.5 8.5 13.0 2.1 8.1 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 ETS84920.1 - 2.5 6.2 15.1 3.1 5.9 10.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HMG_box PF00505.14 ETS84921.1 - 2.1e-13 50.3 3.5 2.1e-13 50.3 2.4 2.3 1 1 1 2 2 2 1 HMG (high mobility group) box DUF3513 PF12026.3 ETS84921.1 - 0.15 11.5 8.3 0.31 10.5 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) DUF1510 PF07423.6 ETS84921.1 - 0.71 9.2 13.1 1.4 8.2 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CAF-1_p150 PF11600.3 ETS84921.1 - 4.6 6.5 24.8 0.83 8.9 12.9 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HlyC PF02794.11 ETS84923.1 - 0.034 13.7 0.1 0.097 12.2 0.1 1.7 1 0 0 1 1 1 0 RTX toxin acyltransferase family zf-MYND PF01753.13 ETS84923.1 - 7.3 6.5 20.4 0.26 11.2 2.5 3.5 3 1 0 3 3 3 0 MYND finger MAGE PF01454.14 ETS84924.1 - 1.8e-43 148.1 0.0 2.4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family CDC45 PF02724.9 ETS84924.1 - 0.22 9.5 2.9 0.3 9.0 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DTHCT PF08070.6 ETS84924.1 - 1.1 9.9 7.8 0.18 12.4 0.8 2.5 2 1 0 2 2 2 0 DTHCT (NUC029) region Mating_C PF12737.2 ETS84924.1 - 2 7.2 10.1 2.5 6.9 3.7 2.0 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 SLS PF14611.1 ETS84925.1 - 1.3e-29 103.1 1.1 2.7e-29 102.0 0.8 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.22 ETS84926.1 - 1.8e-58 197.0 0.0 2.8e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 ETS84926.1 - 5.7e-37 125.8 0.0 1.5e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 ETS84926.1 - 3.6e-17 62.2 2.0 4.6e-17 61.8 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS84926.1 - 0.00026 20.9 0.6 0.00084 19.2 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 ETS84926.1 - 0.00037 20.0 0.1 0.00099 18.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Dynamin_N PF00350.18 ETS84926.1 - 0.035 13.9 0.1 8.4 6.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 ETS84926.1 - 0.1 11.8 0.2 1.4 8.1 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Fungal_trans PF04082.13 ETS84928.1 - 1e-17 63.9 0.5 1.8e-17 63.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS84928.1 - 0.0014 18.5 7.0 0.0024 17.7 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2702 PF10863.3 ETS84928.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) p450 PF00067.17 ETS84929.1 - 1.2e-57 195.4 0.0 1.4e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec2p PF06428.6 ETS84930.1 - 1.8e-23 82.2 12.9 1.8e-23 82.2 9.0 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF310 PF03750.8 ETS84930.1 - 0.02 15.0 1.9 0.038 14.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF3584 PF12128.3 ETS84930.1 - 0.94 6.7 23.6 1.5 6.0 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_S46 PF10459.4 ETS84930.1 - 5.7 5.2 12.1 8.1 4.7 8.4 1.1 1 0 0 1 1 1 0 Peptidase S46 Pro-kuma_activ PF09286.6 ETS84933.1 - 5.5e-42 143.2 0.0 1.3e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF3433 PF11915.3 ETS84934.1 - 5.8e-26 90.4 1.6 5.8e-26 90.4 1.1 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Borrelia_P83 PF05262.6 ETS84936.1 - 1 7.5 8.1 7.2 4.7 0.1 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein SCO1-SenC PF02630.9 ETS84937.1 - 1.8e-59 200.2 0.0 2.5e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 ETS84937.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 ETS84937.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 ETS84937.1 - 0.075 12.5 0.0 1.3 8.5 0.0 2.2 1 1 0 1 1 1 0 Redoxin Ank_2 PF12796.2 ETS84940.1 - 4.9e-10 39.6 0.0 0.077 13.3 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS84940.1 - 6.3e-07 29.0 1.3 0.74 10.2 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 ETS84940.1 - 8.1e-07 29.3 0.1 0.047 14.2 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS84940.1 - 5.2e-05 22.8 9.2 1.9 8.4 0.0 5.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 ETS84940.1 - 0.049 13.8 1.5 5.9 7.2 0.0 3.7 5 0 0 5 5 5 0 Ankyrin repeats (many copies) DUF1908 PF08926.6 ETS84940.1 - 0.054 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) RicinB_lectin_2 PF14200.1 ETS84941.1 - 3e-19 69.3 6.8 2.2e-12 47.2 2.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 ETS84941.1 - 1.4e-08 34.8 5.4 6.3e-06 26.2 0.3 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain 4HBT_3 PF13622.1 ETS84942.1 - 1.3e-26 93.8 0.4 1.6e-26 93.5 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 ETS84942.1 - 0.00019 21.4 0.1 0.18 11.9 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Acyl_CoA_thio PF02551.10 ETS84942.1 - 0.0055 16.3 0.7 5.7 6.5 0.1 2.8 2 1 1 3 3 3 2 Acyl-CoA thioesterase ADH_zinc_N PF00107.21 ETS84943.1 - 1e-20 73.5 0.0 1.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS84943.1 - 4e-06 27.7 0.0 7.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PSDC PF12588.3 ETS84944.1 - 2.2e-30 105.1 0.1 3.7e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 ETS84944.1 - 1.1e-24 86.8 0.0 1.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase F-box PF00646.28 ETS84945.1 - 3.1 7.5 5.2 1.3 8.7 1.4 2.1 2 0 0 2 2 2 0 F-box domain HET PF06985.6 ETS84947.1 - 1.9e-24 86.3 5.1 7.1e-22 78.0 3.5 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VCBS PF13517.1 ETS84947.1 - 0.13 12.6 4.8 0.24 11.7 0.1 3.6 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glyco_hydro_43 PF04616.9 ETS84949.1 - 1.1e-38 133.0 8.0 1.4e-38 132.6 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 VCBS PF13517.1 ETS84950.1 - 0.43 10.9 6.5 5.8 7.3 0.1 3.8 3 2 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p450 PF00067.17 ETS84951.1 - 1.2e-38 132.8 0.0 1.3e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 ETS84951.1 - 0.051 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF2255 PF10012.4 ETS84951.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF3656 PF12392.3 ETS84953.1 - 0.064 13.3 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Collagenase EcKinase PF02958.15 ETS84955.1 - 1e-18 67.5 0.0 2.2e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 ETS84955.1 - 8.9e-09 35.4 0.8 1.2e-08 34.9 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 ETS84955.1 - 9.6e-09 34.3 0.1 1.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TRI5 PF06330.6 ETS84956.1 - 1.3e-11 43.8 0.0 1.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) fn3_3 PF14686.1 ETS84957.1 - 7.6e-12 45.1 0.7 1.2e-11 44.6 0.5 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 ETS84957.1 - 5.4e-11 42.3 0.3 1.2e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.5 ETS84957.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CarboxypepD_reg PF13620.1 ETS84957.1 - 0.0014 18.6 1.1 0.0025 17.8 0.8 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Acylphosphatase PF00708.13 ETS84957.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase CBM-like PF14683.1 ETS84958.1 - 4.1e-16 59.0 0.1 7.2e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 ETS84958.1 - 1.3e-08 34.7 0.2 5.6e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II Glyco_hydro_28 PF00295.12 ETS84960.1 - 1e-15 57.5 0.0 4.5e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_2_N PF02837.13 ETS84961.1 - 1.5e-27 96.2 0.3 2.3e-27 95.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.1 ETS84961.1 - 3e-06 27.4 1.1 5.1e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain F5_F8_type_C PF00754.20 ETS84962.1 - 2.7e-05 24.0 2.8 8.8e-05 22.3 1.9 1.9 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_10 PF00331.15 ETS84963.1 - 6e-85 285.0 0.8 1.2e-80 270.9 0.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 Lipase_GDSL_2 PF13472.1 ETS84964.1 - 1.2e-20 74.3 0.6 1.5e-20 74.0 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS84964.1 - 1e-12 48.4 0.3 1.4e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RNase_PH PF01138.16 ETS84965.1 - 2.2e-18 66.8 0.0 4.9e-18 65.7 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Ferric_reduct PF01794.14 ETS84966.1 - 7.9e-18 64.7 5.0 7.9e-18 64.7 3.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 ETS84966.1 - 2.1e-14 53.2 0.1 6.1e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 ETS84966.1 - 1.1e-13 51.4 0.0 6.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 ETS84966.1 - 0.00023 21.6 0.0 0.065 13.8 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 ETS84966.1 - 0.42 10.7 4.6 0.18 11.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PAT1 PF09770.4 ETS84966.1 - 2.1 6.4 12.4 3 5.9 8.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HET PF06985.6 ETS84967.1 - 2.8e-19 69.6 13.9 2.6e-16 60.0 2.4 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF570 PF04489.8 ETS84967.1 - 0.012 14.0 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Hydrolase_6 PF13344.1 ETS84968.1 - 2.6e-25 88.2 0.0 6.9e-25 86.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS84968.1 - 6.8e-18 64.1 0.0 3.2e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 ETS84968.1 - 1.1e-06 28.9 0.0 0.013 15.7 0.0 3.8 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS84968.1 - 5.9e-05 23.5 0.0 0.36 11.2 0.0 3.1 2 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS84968.1 - 0.028 14.6 0.0 0.71 10.0 0.0 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS84968.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 ETS84969.1 - 9.2e-57 192.0 0.0 3.4e-56 190.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 ETS84969.1 - 3.3e-21 74.4 0.0 8.1e-21 73.2 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus PHD PF00628.24 ETS84970.1 - 6.5e-12 44.9 7.5 6.5e-12 44.9 5.2 2.3 2 0 0 2 2 2 1 PHD-finger Med3 PF11593.3 ETS84970.1 - 0.0045 16.2 0.1 0.0057 15.9 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C2H2 PF00096.21 ETS84972.1 - 1.2e-08 34.7 13.3 0.00034 20.7 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS84972.1 - 5.2e-07 29.6 9.8 1.1e-06 28.5 1.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS84972.1 - 8e-05 22.7 12.0 0.01 16.1 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 ETS84972.1 - 0.014 15.6 3.4 0.034 14.3 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS84972.1 - 0.059 13.5 0.7 0.059 13.5 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 ETS84972.1 - 0.34 10.9 2.3 8.3 6.4 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 ETS84972.1 - 3.2 7.5 7.8 22 4.8 1.3 2.4 1 1 1 2 2 2 0 BED zinc finger PI3Ka PF00613.15 ETS84973.1 - 3.3e-58 195.9 2.7 6.7e-58 194.9 1.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 ETS84973.1 - 2.2e-44 151.6 0.0 1.5e-43 148.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 ETS84973.1 - 3.6e-29 101.3 0.0 6.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 ETS84973.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Nse4_C PF08743.5 ETS84974.1 - 5.5e-29 100.0 0.0 1.3e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 ETS84974.1 - 1e-13 50.8 0.0 2.8e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE APG6 PF04111.7 ETS84975.1 - 6.4e-05 22.1 19.2 6.4e-05 22.1 13.3 8.9 3 2 8 11 11 11 4 Autophagy protein Apg6 IncA PF04156.9 ETS84975.1 - 0.0002 21.0 20.4 0.0002 21.0 14.1 9.4 3 3 4 8 8 8 4 IncA protein TPR_MLP1_2 PF07926.7 ETS84975.1 - 0.004 16.9 13.0 0.004 16.9 9.0 10.2 3 2 4 8 8 8 1 TPR/MLP1/MLP2-like protein COX1 PF00115.15 ETS84975.1 - 0.24 9.9 0.9 0.32 9.5 0.6 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF4336 PF14234.1 ETS84976.1 - 1.7e-15 56.9 0.1 1.2e-11 44.2 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) AA_permease_2 PF13520.1 ETS84977.1 - 2.2e-66 224.1 13.5 2.9e-66 223.7 9.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS84977.1 - 1.1e-11 43.8 15.3 3.5e-11 42.1 7.6 2.1 2 0 0 2 2 2 2 Amino acid permease ALO PF04030.9 ETS84978.1 - 1e-89 300.6 0.7 1e-89 300.6 0.5 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 ETS84978.1 - 8.7e-29 99.7 0.0 1.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BCMA-Tall_bind PF09257.5 ETS84979.1 - 0.022 14.7 1.1 0.051 13.5 0.8 1.6 1 0 0 1 1 1 0 BCMA, TALL-1 binding CNH PF00780.17 ETS84980.1 - 9.1e-83 277.8 0.0 3.3e-82 276.0 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 ETS84980.1 - 1.2e-40 138.5 0.1 2.8e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 ETS84980.1 - 3.2e-35 121.6 0.1 6.7e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 ETS84980.1 - 3e-15 55.7 0.0 5.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 ETS84981.1 - 2.3e-26 91.4 30.4 1.4e-15 56.9 4.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TctB PF07331.6 ETS84981.1 - 2.8 7.5 15.7 1e+02 2.5 10.9 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family FPN1 PF06963.7 ETS84981.1 - 3.1 6.0 7.6 9.8 4.4 0.0 2.8 2 1 1 3 3 3 0 Ferroportin1 (FPN1) DUF2201_N PF13203.1 ETS84983.1 - 0.3 10.2 4.0 0.38 9.8 2.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 ETS84983.1 - 0.36 8.8 7.9 0.4 8.6 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 ETS84983.1 - 0.59 8.4 7.4 2.8 6.2 3.4 2.0 2 0 0 2 2 2 0 Hsp90 protein RR_TM4-6 PF06459.7 ETS84983.1 - 1.6 8.5 6.8 1.9 8.2 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 ETS84983.1 - 7.8 5.9 11.2 10 5.5 7.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Rad21_Rec8_N PF04825.8 ETS84984.1 - 7.9e-28 96.6 0.1 1.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 ETS84984.1 - 1.1e-07 30.9 0.0 2.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein AT_hook PF02178.14 ETS84984.1 - 0.59 9.9 5.3 1.5 8.7 3.7 1.7 1 0 0 1 1 1 0 AT hook motif GDI PF00996.13 ETS84985.1 - 5e-35 120.6 0.0 3.1e-34 118.0 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor DUF202 PF02656.10 ETS84988.1 - 2.1e-18 66.2 0.3 1.4e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2962 PF11176.3 ETS84988.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) DUF2910 PF11139.3 ETS84988.1 - 0.25 10.4 2.3 0.78 8.8 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) DUF327 PF03885.8 ETS84989.1 - 0.0059 16.4 3.1 0.44 10.3 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF327) DUF2365 PF10157.4 ETS84989.1 - 0.0087 15.9 0.6 0.011 15.5 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 ETS84989.1 - 0.015 15.2 1.7 0.44 10.5 0.3 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 PDZ_1 PF12812.2 ETS84989.1 - 0.04 13.8 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 PDZ-like domain BBP1_C PF15272.1 ETS84989.1 - 0.044 13.3 8.0 0.077 12.5 5.1 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal UreE_C PF05194.7 ETS84989.1 - 0.078 13.0 8.6 0.17 12.0 6.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Tup_N PF08581.5 ETS84989.1 - 0.11 12.7 8.3 0.035 14.2 3.7 1.7 2 0 0 2 2 1 0 Tup N-terminal Zip PF02535.17 ETS84989.1 - 0.14 11.1 4.0 0.14 11.1 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSBP1 PF06825.7 ETS84989.1 - 0.14 11.7 3.5 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Syntaxin PF00804.20 ETS84989.1 - 0.15 12.2 7.4 2.5 8.3 0.9 2.7 1 1 1 2 2 2 0 Syntaxin CENP-F_leu_zip PF10473.4 ETS84989.1 - 0.94 9.3 4.5 4.8 7.0 0.1 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Not3 PF04065.10 ETS84989.1 - 1.2 8.3 6.5 0.5 9.6 2.0 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component YlqD PF11068.3 ETS84989.1 - 1.8 8.6 5.6 6.6 6.7 0.9 2.3 1 1 2 3 3 3 0 YlqD protein FliJ PF02050.11 ETS84989.1 - 1.8 8.5 10.4 8.7 6.4 0.7 2.5 1 1 2 3 3 3 0 Flagellar FliJ protein IncA PF04156.9 ETS84989.1 - 3.9 7.0 10.6 7.1 6.1 7.3 1.5 1 1 0 1 1 1 0 IncA protein ADH_zinc_N PF00107.21 ETS84991.1 - 3.1e-14 52.6 0.0 5.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS84991.1 - 0.00038 21.3 0.0 0.00068 20.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UQ_con PF00179.21 ETS84992.1 - 6.2e-46 155.3 0.0 7.1e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS84992.1 - 7e-05 22.5 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 ETS84992.1 - 0.047 13.3 0.1 0.096 12.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 ETS84992.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 ETS84993.1 - 7.3e-10 38.3 18.8 3.8e-06 26.5 0.2 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 ETS84993.1 - 0.052 13.3 9.0 0.11 12.3 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain Ank_2 PF12796.2 ETS84994.1 - 6.3e-93 305.2 3.7 6.4e-22 77.7 0.0 5.8 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS84994.1 - 1.4e-70 229.8 1.4 5.1e-09 35.4 0.0 10.3 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 ETS84994.1 - 3.8e-54 179.4 6.3 1.3e-10 41.1 0.0 7.4 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS84994.1 - 3e-53 177.2 5.6 1.8e-13 50.6 0.0 7.8 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS84994.1 - 1.4e-50 164.2 0.1 0.00018 21.3 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat AAA_33 PF13671.1 ETS84994.1 - 4.5e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS84994.1 - 1.2e-06 28.6 0.0 3.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS84994.1 - 2.3e-06 27.7 0.6 1.6e-05 25.0 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS84994.1 - 7.1e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 ETS84994.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 ETS84994.1 - 0.00084 19.2 0.0 0.0025 17.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 ETS84994.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 ETS84994.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 ETS84994.1 - 0.055 14.2 0.0 0.3 11.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 ETS84994.1 - 0.057 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PNP_UDP_1 PF01048.15 ETS84995.1 - 0.00027 19.9 0.0 0.0052 15.7 0.0 2.2 2 0 0 2 2 2 2 Phosphorylase superfamily F-box PF00646.28 ETS84996.1 - 0.0038 16.8 0.3 0.0038 16.8 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS84996.1 - 0.0082 15.8 2.5 0.011 15.4 0.6 2.2 1 1 1 2 2 2 1 F-box-like p450 PF00067.17 ETS84997.1 - 6.1e-65 219.5 0.0 7.4e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS84998.1 - 4.1e-12 46.3 0.0 6.9e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS84998.1 - 0.00031 20.4 0.1 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS84998.1 - 0.00099 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RanGAP1_C PF07834.6 ETS84998.1 - 0.051 13.0 0.1 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 RanGAP1 C-terminal domain Pal1 PF08316.6 ETS84999.1 - 1.2e-46 158.6 0.3 1.2e-46 158.6 0.2 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein Fasciclin PF02469.17 ETS85001.1 - 2.5e-45 153.5 0.0 2.6e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_88 PF07470.8 ETS85002.1 - 9.7e-37 126.7 2.0 2.3e-19 69.6 0.1 2.4 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 F-box-like PF12937.2 ETS85003.1 - 0.00092 18.8 1.2 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like HSP70 PF00012.15 ETS85005.1 - 1.5e-76 257.6 1.5 1.5e-76 257.6 1.1 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 ETS85005.1 - 3.2e-07 29.2 0.4 5e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Pap_E4 PF02711.9 ETS85005.1 - 0.0071 17.1 0.3 0.017 15.8 0.2 1.7 1 0 0 1 1 1 1 E4 protein Nucleoplasmin PF03066.10 ETS85005.1 - 0.013 15.0 3.2 0.027 13.9 2.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF506 PF04720.7 ETS85005.1 - 0.1 12.1 1.1 0.19 11.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF506) FAM176 PF14851.1 ETS85005.1 - 0.11 12.2 1.8 0.22 11.1 1.3 1.5 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 ETS85005.1 - 0.38 11.0 6.0 1 9.7 4.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 ETS85005.1 - 0.42 10.4 3.4 0.92 9.2 2.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 ETS85005.1 - 0.71 9.4 8.6 0.14 11.7 2.6 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 ETS85005.1 - 3.1 5.4 7.6 5 4.7 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi NT-C2 PF10358.4 ETS85006.1 - 1e-22 80.1 0.0 3.1e-22 78.6 0.0 1.7 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins BORG_CEP PF14957.1 ETS85006.1 - 3.5 8.5 6.1 14 6.6 3.9 2.2 1 1 0 1 1 1 0 Cdc42 effector POP1 PF06978.6 ETS85007.1 - 1.3e-56 191.2 14.7 1.3e-56 191.2 10.2 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 ETS85007.1 - 7.5e-30 102.6 0.2 7.5e-30 102.6 0.2 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain FAD_binding_4 PF01565.18 ETS85008.1 - 9.1e-18 64.0 1.5 1.3e-17 63.5 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 ETS85008.1 - 2.5e-08 33.8 0.3 0.00013 21.6 0.0 2.5 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase 2OG-FeII_Oxy_2 PF13532.1 ETS85009.1 - 2.6e-19 69.8 0.1 2.1e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS85009.1 - 0.0022 18.2 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipase_GDSL_2 PF13472.1 ETS85011.1 - 7e-06 26.2 0.3 1.1e-05 25.6 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Acyl-CoA_dh_1 PF00441.19 ETS85012.1 - 4e-33 114.6 0.9 5.6e-33 114.1 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 ETS85012.1 - 9.7e-18 63.4 0.7 2e-17 62.4 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 ETS85012.1 - 3.2e-14 53.4 0.6 1.1e-13 51.7 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 ETS85012.1 - 1.9e-06 28.1 0.8 3.3e-06 27.3 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.17 ETS85013.1 - 2e-17 62.5 0.0 1.1e-12 47.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS85013.1 - 1.1e-09 38.1 0.0 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS85013.1 - 0.0066 16.2 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 ETS85014.1 - 8.7e-48 161.7 0.0 1e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS85014.1 - 4.7e-16 59.3 0.0 3.8e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS85014.1 - 1.4e-05 24.4 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 ETS85014.1 - 0.00027 20.4 0.0 0.0006 19.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 ETS85014.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase hEGF PF12661.2 ETS85016.1 - 0.09 12.8 2.6 0.2 11.8 1.8 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 ETS85016.1 - 8.9 6.5 12.3 17 5.6 8.5 1.4 1 0 0 1 1 1 0 EGF-like domain HnRNP_M PF11532.3 ETS85017.1 - 0.082 13.0 1.5 0.26 11.3 1.1 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M BNR PF02012.15 ETS85018.1 - 0.054 13.3 0.4 0.2 11.5 0.3 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Adeno_shaft PF00608.12 ETS85018.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Amidohydro_4 PF13147.1 ETS85019.1 - 9.8e-14 52.0 2.7 3.2e-11 43.7 0.1 3.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 ETS85019.1 - 2.6e-07 30.3 0.6 7.1e-06 25.7 0.2 2.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS85019.1 - 0.00016 20.9 0.2 0.00058 19.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.15 ETS85019.1 - 0.00021 21.0 5.5 0.00033 20.4 1.5 2.9 2 1 0 2 2 2 1 Amidohydrolase family NmrA PF05368.8 ETS85020.1 - 1.9e-54 184.4 0.1 2.4e-54 184.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS85020.1 - 3.2e-15 56.6 0.0 5.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS85020.1 - 4.6e-05 22.2 0.1 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RTC PF01137.16 ETS85020.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase adh_short PF00106.20 ETS85021.1 - 7.3e-18 65.0 0.8 1e-17 64.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85021.1 - 3.4e-08 33.5 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85021.1 - 8.9e-08 31.9 0.3 1.7e-07 31.1 0.2 1.5 1 1 0 1 1 1 1 KR domain DUF3755 PF12579.3 ETS85021.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Abhydrolase_6 PF12697.2 ETS85023.1 - 8.5e-25 87.9 0.0 1.3e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85023.1 - 9.8e-09 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 ETS85023.1 - 3.4e-05 22.4 0.0 5.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 ETS85023.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 ETS85023.1 - 0.0011 19.8 0.5 0.95 10.4 0.0 2.8 3 0 0 3 3 3 2 EthD domain DUF4286 PF14114.1 ETS85023.1 - 0.005 17.0 0.4 0.77 10.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) Esterase PF00756.15 ETS85023.1 - 0.036 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF1381 PF07129.6 ETS85024.1 - 0.024 14.0 0.1 0.067 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) RdRP PF05183.7 ETS85026.1 - 3.5e-162 541.1 0.0 4.4e-162 540.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pyr_redox_2 PF07992.9 ETS85027.1 - 0.0022 17.8 0.0 0.0094 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS85027.1 - 0.0036 16.4 0.0 0.01 14.9 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 ETS85027.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 ETS85027.1 - 0.04 13.9 0.4 0.18 11.8 0.3 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS85027.1 - 0.055 13.2 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 ETS85027.1 - 0.092 13.1 0.1 0.68 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS85027.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS85027.1 - 0.17 10.7 0.4 0.94 8.3 0.0 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein zf-UBR PF02207.15 ETS85028.1 - 6.7e-14 51.3 9.0 1e-13 50.7 6.2 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Lactamase_B PF00753.22 ETS85029.1 - 8e-06 25.6 0.9 8.7e-05 22.2 0.6 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS85029.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Epimerase PF01370.16 ETS85030.1 - 1.1e-59 201.7 0.0 1.5e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS85030.1 - 6.1e-23 80.9 0.0 8.2e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS85030.1 - 4.9e-21 74.8 0.0 5.5e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS85030.1 - 4.9e-18 64.9 0.1 9.8e-17 60.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 ETS85030.1 - 1.2e-17 63.7 0.0 1.7e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS85030.1 - 1.2e-07 31.9 0.0 4.7e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS85030.1 - 0.00022 21.1 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85030.1 - 0.071 12.7 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 KR domain Pkinase PF00069.20 ETS85031.1 - 9.6e-58 195.3 0.0 1.4e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85031.1 - 8.4e-37 126.6 0.1 4.7e-36 124.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS85031.1 - 1.3e-05 24.3 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS85031.1 - 0.0025 17.6 0.1 0.028 14.1 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family NCA2 PF08637.5 ETS85031.1 - 0.05 12.5 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 DUF607 PF04678.8 ETS85031.1 - 0.082 12.8 0.4 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 OmpH PF03938.9 ETS85031.1 - 0.55 10.1 5.2 0.98 9.3 2.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3896 PF13035.1 ETS85031.1 - 0.61 10.1 4.3 7.6 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TMF_DNA_bd PF12329.3 ETS85031.1 - 2.4 7.9 10.2 0.2 11.4 2.3 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BTB PF00651.26 ETS85032.1 - 3.7e-26 91.2 0.0 5e-13 49.0 0.1 3.2 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 ETS85032.1 - 7.4e-10 39.0 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS85032.1 - 4.2e-08 33.4 0.0 9.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 ETS85032.1 - 6.8e-08 31.9 0.2 6.3e-05 22.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 ETS85032.1 - 1.9e-05 24.7 0.0 5.7e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85032.1 - 0.00011 22.0 0.1 0.035 14.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Metallophos PF00149.23 ETS85034.1 - 5.1e-07 29.2 2.2 9.5e-07 28.4 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidase PF01425.16 ETS85035.1 - 4e-97 325.8 0.1 5.5e-97 325.4 0.1 1.1 1 0 0 1 1 1 1 Amidase PRP38 PF03371.10 ETS85036.1 - 2.4e-59 199.8 0.0 3.1e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Isy1 PF06246.7 ETS85037.1 - 6.7e-81 271.4 0.3 8.7e-81 271.0 0.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 ETS85037.1 - 0.0051 16.6 0.2 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 YolD-like protein Mistic PF11458.3 ETS85037.1 - 1.8 8.9 4.8 2.2 8.7 0.2 2.5 3 0 0 3 3 3 0 Membrane-integrating protein Mistic Acetyltransf_3 PF13302.1 ETS85038.1 - 4e-21 75.6 0.0 5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS85038.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein NACHT PF05729.7 ETS85040.1 - 7.8e-12 45.1 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS85040.1 - 8.3e-05 22.7 0.1 0.00052 20.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 ETS85040.1 - 0.0018 18.5 0.0 0.011 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS85040.1 - 0.0022 17.4 0.0 0.014 14.8 0.0 2.3 3 0 0 3 3 3 1 AAA-like domain RNA_helicase PF00910.17 ETS85040.1 - 0.026 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 ETS85040.1 - 0.031 15.0 0.0 0.16 12.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 ETS85040.1 - 0.067 13.4 0.1 0.63 10.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 ETS85040.1 - 0.081 12.4 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NST1 PF13945.1 ETS85041.1 - 0.022 14.8 2.5 0.038 14.0 1.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Pectate_lyase PF03211.8 ETS85042.1 - 3.9e-76 255.2 7.5 1.2e-75 253.6 5.2 1.6 1 1 0 1 1 1 1 Pectate lyase Acetyltransf_10 PF13673.1 ETS85043.1 - 4.3e-09 36.5 0.1 8.9e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS85043.1 - 2.3e-05 24.2 0.0 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS85043.1 - 3.2e-05 23.8 0.0 5.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS85043.1 - 5.9e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS85043.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein ArgJ PF01960.13 ETS85043.1 - 0.095 11.0 0.2 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 ArgJ family Tyrosinase PF00264.15 ETS85044.1 - 5.5e-31 108.4 1.4 1.1e-30 107.4 1.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_3 PF00933.16 ETS85045.1 - 1.2e-82 277.3 0.0 1.8e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS85045.1 - 4.7e-43 147.3 2.7 1.9e-42 145.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS85045.1 - 1.1e-26 92.5 0.1 2.2e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 ETS85046.1 - 2.2e-28 99.0 32.6 2.8e-28 98.6 22.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PMSR PF01625.16 ETS85047.1 - 4.1e-60 202.1 0.1 4.8e-60 201.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.15 ETS85048.1 - 4e-32 111.5 11.4 6.3e-32 110.8 7.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMP_binding PF00027.24 ETS85049.1 - 9.2e-36 121.5 0.0 4.7e-19 67.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 ETS85049.1 - 5.4e-13 47.5 9.3 0.19 11.8 0.1 8.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.1 ETS85049.1 - 1.8e-06 27.5 1.6 0.56 10.0 0.2 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 ETS85049.1 - 3.7e-06 26.4 0.0 0.63 9.7 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 ETS85049.1 - 1e-05 24.8 7.4 5.5 7.4 0.2 7.3 7 1 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.28 ETS85049.1 - 0.0015 18.1 2.1 0.0015 18.1 1.5 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 ETS85049.1 - 0.0031 17.1 2.7 0.0031 17.1 1.9 2.2 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 ETS85049.1 - 0.12 12.6 12.4 14 6.3 0.0 6.0 7 0 0 7 7 7 0 Leucine rich repeat ADH_zinc_N PF00107.21 ETS85050.1 - 1.4e-26 92.5 0.1 3.7e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS85050.1 - 7e-20 72.2 0.1 2.6e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS85050.1 - 8.5e-09 35.1 0.8 1.7e-08 34.1 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PDZ PF00595.19 ETS85050.1 - 0.07 13.3 0.2 0.28 11.4 0.0 2.1 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) ADH_zinc_N PF00107.21 ETS85051.1 - 2.7e-16 59.3 0.0 4.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS85051.1 - 3.6e-09 37.5 0.0 6.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS85051.1 - 3.4e-07 29.9 0.1 1e-05 25.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF938 PF06080.7 ETS85051.1 - 0.012 15.2 0.0 0.042 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Fungal_trans PF04082.13 ETS85052.1 - 6e-21 74.4 0.2 1.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85052.1 - 1.6e-08 34.2 11.3 3e-08 33.4 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 ETS85053.1 - 3.5e-20 72.5 2.7 4.9e-20 72.1 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85053.1 - 7.3e-08 32.4 0.0 2.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85053.1 - 6.5e-07 29.1 2.0 1.6e-06 27.8 1.4 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS85053.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein XLF PF09302.6 ETS85055.1 - 6.3e-30 104.1 0.0 9.3e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Cupin_5 PF06172.6 ETS85057.1 - 1.3e-31 109.3 0.0 5.2e-31 107.4 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Fork_head PF00250.13 ETS85058.1 - 7.5e-15 54.7 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain CENP-U PF13097.1 ETS85058.1 - 0.032 14.1 0.1 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Cactin_mid PF10312.4 ETS85059.1 - 2e-62 209.8 1.8 2.9e-62 209.3 1.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 ETS85059.1 - 6e-50 168.0 1.0 1e-49 167.2 0.7 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Herpes_capsid PF06112.6 ETS85059.1 - 2.8 7.9 10.7 6 6.8 7.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Hce2 PF14856.1 ETS85060.1 - 7.9e-11 41.7 0.1 1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CFEM PF05730.6 ETS85061.1 - 3.9e-07 29.8 10.6 1.1e-06 28.3 7.3 1.8 1 0 0 1 1 1 1 CFEM domain DUF347 PF03988.7 ETS85061.1 - 0.0048 16.7 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Rifin_STEVOR PF02009.11 ETS85061.1 - 0.32 10.5 3.4 0.63 9.6 2.3 1.5 1 0 0 1 1 1 0 Rifin/stevor family CDC27 PF09507.5 ETS85061.1 - 0.46 9.6 19.0 0.69 9.0 13.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF966 PF06136.8 ETS85061.1 - 0.62 9.4 9.6 0.76 9.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.8 ETS85061.1 - 0.8 9.5 15.1 0.95 9.2 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 ETS85061.1 - 1.1 7.4 10.5 1.1 7.3 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_BLLF1 PF05109.8 ETS85061.1 - 1.3 6.8 38.5 1.4 6.7 26.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TrbL PF04610.9 ETS85061.1 - 3.7 7.2 7.5 6.4 6.4 5.2 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Peptidase_S64 PF08192.6 ETS85061.1 - 7.8 4.6 8.0 10 4.3 5.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 ACOX PF01756.14 ETS85063.1 - 2.2e-36 125.0 0.3 6.2e-36 123.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 ETS85063.1 - 6.8e-28 97.4 0.6 1.3e-27 96.5 0.4 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 ETS85063.1 - 1.7e-10 40.2 0.4 8e-10 38.0 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 ETS85063.1 - 2.2e-05 24.6 1.0 0.0086 16.1 0.7 3.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L19e PF01280.15 ETS85064.1 - 7.8e-34 116.5 9.2 7.8e-34 116.5 6.4 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 ETS85064.1 - 0.0069 15.6 0.6 0.0078 15.4 0.4 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Atg14 PF10186.4 ETS85064.1 - 0.94 8.3 4.7 1.2 8.0 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3043 PF11241.3 ETS85064.1 - 1.9 8.0 12.6 3.8 7.0 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AA_permease PF00324.16 ETS85065.1 - 9.5e-102 340.7 43.4 1.2e-101 340.4 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS85065.1 - 4e-26 91.5 45.1 4.9e-26 91.2 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease ubiquitin PF00240.18 ETS85066.1 - 2.1e-18 65.4 0.0 5.5e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETS85066.1 - 1.1e-08 34.5 0.0 2.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 ETS85066.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS85066.1 - 0.093 12.9 0.0 0.48 10.7 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Copper-fist PF00649.13 ETS85068.1 - 2.1e-18 65.2 0.8 2.1e-18 65.2 0.5 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain SHMT PF00464.14 ETS85070.1 - 4.9e-195 647.5 0.1 6.1e-195 647.2 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 ETS85070.1 - 0.0027 16.5 0.1 0.0049 15.6 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DUF566 PF04484.7 ETS85070.1 - 0.31 10.5 3.6 0.53 9.7 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) FTA2 PF13095.1 ETS85071.1 - 5.7e-27 94.6 0.0 7.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Hydrolase_6 PF13344.1 ETS85074.1 - 1e-24 86.3 0.0 1.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS85074.1 - 3.2e-12 45.9 0.0 2e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 ETS85074.1 - 0.0045 17.2 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 ETS85075.1 - 8.8e-28 97.3 0.8 1.1e-27 96.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85075.1 - 5e-22 78.8 0.0 6e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85075.1 - 1e-11 44.8 0.2 1.5e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 ETS85075.1 - 0.0034 16.3 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS85075.1 - 0.33 10.9 1.7 2 8.3 0.9 2.2 1 1 0 1 1 1 0 NADH(P)-binding MR_MLE_C PF13378.1 ETS85076.1 - 1.1e-20 73.6 0.0 3.2e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS85076.1 - 3.2e-12 46.7 0.0 8.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 ETS85076.1 - 8.2e-10 38.7 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 ETS85078.1 - 1.7e-24 86.0 1.1 2.8e-24 85.4 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85078.1 - 4e-07 29.8 14.2 6.8e-07 29.0 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 ETS85079.1 - 3.2e-24 84.7 1.5 7.2e-24 83.6 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 ETS85079.1 - 1.5e-08 34.1 0.1 2.9e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 ETS85079.1 - 3.7e-08 32.9 0.2 3.7e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase RRM_1 PF00076.17 ETS85080.1 - 6.6e-51 169.8 0.4 2.9e-16 58.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS85080.1 - 7.6e-46 153.9 0.4 5.4e-13 48.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS85080.1 - 6.9e-25 86.6 0.7 6.8e-08 32.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS85080.1 - 1.9e-05 24.3 0.0 0.026 14.3 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Thioredoxin PF00085.15 ETS85080.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin Methyltransf_2 PF00891.13 ETS85081.1 - 1.1e-30 106.6 0.0 2e-30 105.7 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase HTH_IclR PF09339.5 ETS85081.1 - 0.037 13.5 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.1 ETS85081.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_23 PF13489.1 ETS85081.1 - 0.097 12.3 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain SKG6 PF08693.5 ETS85082.1 - 0.0088 15.3 0.6 0.017 14.4 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain C1-set PF07654.10 ETS85082.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain MHC_I_2 PF14586.1 ETS85082.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 MSC PF09402.5 ETS85082.1 - 0.15 10.7 0.1 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DivIC PF04977.10 ETS85083.1 - 0.0033 16.8 5.2 0.089 12.2 0.7 2.6 1 1 1 2 2 2 2 Septum formation initiator GAS PF13851.1 ETS85083.1 - 0.0054 15.9 8.4 0.0092 15.1 5.8 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Nup54 PF13874.1 ETS85083.1 - 0.029 14.0 6.5 0.089 12.4 4.5 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.3 ETS85083.1 - 0.03 14.1 6.9 0.085 12.6 4.5 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 ETS85083.1 - 0.035 14.2 3.3 0.082 13.0 2.3 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.6 ETS85083.1 - 0.12 12.2 1.8 0.28 10.9 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF2570 PF10828.3 ETS85083.1 - 0.17 11.4 7.2 0.38 10.3 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DMPK_coil PF08826.5 ETS85083.1 - 0.21 11.5 10.7 0.17 11.8 4.4 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like APG6 PF04111.7 ETS85083.1 - 0.21 10.6 10.6 0.35 9.8 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 ETS85083.1 - 0.29 10.1 5.5 0.5 9.3 3.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.1 ETS85083.1 - 0.34 10.9 11.9 0.69 9.9 8.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Nsp1_C PF05064.8 ETS85083.1 - 0.5 10.0 9.7 0.19 11.3 1.8 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region Macoilin PF09726.4 ETS85083.1 - 0.62 8.2 10.1 0.82 7.8 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 ETS85083.1 - 0.95 9.8 8.6 1.5 9.2 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 ETS85083.1 - 6.7 7.0 12.9 10 6.5 4.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 ETS85083.1 - 8.1 4.1 7.1 13 3.4 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family p450 PF00067.17 ETS85084.1 - 1.1e-63 215.3 0.0 1.3e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 ETS85085.1 - 9.8e-12 44.8 2.0 1.9e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS85085.1 - 6.6e-08 32.7 0.0 5.3e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS85085.1 - 8.6e-07 29.1 1.7 1.4e-05 25.1 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 ETS85085.1 - 0.00034 21.4 0.0 0.0026 18.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 ETS85085.1 - 0.0004 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 ETS85085.1 - 0.00069 19.9 0.0 0.003 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETS85085.1 - 0.00071 19.3 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 ETS85085.1 - 0.0042 16.9 0.1 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS85085.1 - 0.0078 15.6 0.0 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 ETS85085.1 - 0.013 15.3 0.1 0.17 11.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 ABC_tran PF00005.22 ETS85085.1 - 0.017 15.4 0.1 0.16 12.2 0.0 2.5 1 1 0 2 2 2 0 ABC transporter AAA PF00004.24 ETS85085.1 - 0.02 15.0 0.0 0.15 12.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 ETS85085.1 - 0.035 13.1 0.9 0.21 10.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_11 PF13086.1 ETS85085.1 - 0.06 12.9 0.3 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 ETS85085.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 ETS85085.1 - 0.12 12.6 0.5 15 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 ETS85085.1 - 0.15 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 ETS85085.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 ETS85085.1 - 0.2 11.6 0.0 0.63 10.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Shikimate_dh_N PF08501.6 ETS85086.1 - 2.2e-22 78.9 0.0 5e-22 77.7 0.0 1.6 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 ETS85086.1 - 1.8e-12 47.5 0.0 3.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.12 ETS85087.1 - 1.4e-35 122.3 0.1 4.2e-32 110.9 0.0 2.5 2 1 0 2 2 2 2 CoA-transferase family III SANTA PF09133.5 ETS85087.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 SANTA (SANT Associated) DUF1446 PF07287.6 ETS85088.1 - 6.1e-137 455.9 0.0 7.9e-137 455.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Thioredoxin PF00085.15 ETS85089.1 - 8.2e-12 44.7 0.1 3.9e-09 36.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 ETS85089.1 - 0.0011 19.1 0.6 0.0027 17.8 0.1 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 ETS85089.1 - 0.054 13.5 0.3 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.1 ETS85089.1 - 0.14 12.2 0.3 0.99 9.5 0.2 2.2 1 1 0 1 1 1 0 Thioredoxin-like Fungal_trans PF04082.13 ETS85090.1 - 4.6e-06 25.6 0.0 9.8e-06 24.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 ETS85091.1 - 1.7e-68 231.1 0.0 2.1e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS85091.1 - 0.00015 21.2 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 ETS85091.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sugar_tr PF00083.19 ETS85092.1 - 9.7e-87 291.4 21.3 1.2e-86 291.1 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85092.1 - 9.1e-22 77.2 31.2 4e-13 48.8 6.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.19 ETS85093.1 - 3.8e-44 151.5 0.8 9.1e-44 150.2 0.5 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS85093.1 - 2.6e-14 52.9 0.3 6.9e-14 51.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS85093.1 - 1.9e-08 33.6 2.6 7.9e-07 28.2 0.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS85093.1 - 1.2e-05 24.3 1.0 1.8e-05 23.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS85093.1 - 2.4e-05 24.6 0.1 5.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS85093.1 - 4e-05 22.2 0.1 6.4e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 ETS85093.1 - 4.7e-05 22.5 0.1 7.7e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 ETS85093.1 - 0.00015 20.9 0.5 0.00024 20.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS85093.1 - 0.00029 19.9 0.1 0.00045 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS85093.1 - 0.00049 20.2 0.5 0.042 13.9 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85093.1 - 0.0052 16.6 0.2 0.0095 15.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 ETS85093.1 - 0.0093 14.3 0.0 0.018 13.3 0.0 1.4 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 ETS85093.1 - 0.0095 14.8 1.4 0.014 14.3 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 ETS85093.1 - 0.011 14.6 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 ETS85093.1 - 0.031 14.0 1.2 0.69 9.6 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HET PF06985.6 ETS85094.1 - 1.9e-28 99.3 0.3 3.8e-28 98.3 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 ETS85096.1 - 2.1e-19 70.0 0.0 3.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS85096.1 - 0.00043 20.3 0.2 0.0013 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS85096.1 - 0.00065 19.8 0.1 0.033 14.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 ETS85096.1 - 0.0015 18.3 0.0 0.02 14.5 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 ETS85096.1 - 0.0019 19.0 0.2 0.0076 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS85096.1 - 0.022 14.7 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS85096.1 - 0.028 14.1 0.4 0.07 12.8 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 ETS85096.1 - 0.029 14.6 0.0 0.092 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 ETS85096.1 - 0.03 13.9 0.2 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 ETS85096.1 - 0.047 13.5 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS85096.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 ETS85096.1 - 0.055 12.5 0.2 0.099 11.6 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ARID PF01388.16 ETS85097.1 - 1.6e-15 56.7 0.0 5.4e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SKG6 PF08693.5 ETS85098.1 - 0.00018 20.7 0.9 0.00018 20.7 0.6 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 ETS85098.1 - 0.15 11.6 0.9 0.23 11.0 0.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family Mito_fiss_reg PF05308.6 ETS85098.1 - 0.27 10.5 19.0 0.11 11.8 2.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Macoilin PF09726.4 ETS85098.1 - 9.6 4.3 11.9 11 4.0 8.3 1.2 1 0 0 1 1 1 0 Transmembrane protein HATPase_c PF02518.21 ETS85099.1 - 3.9e-21 74.8 0.0 7.3e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS85099.1 - 8.3e-21 74.0 2.3 3.4e-14 52.8 0.1 3.2 3 0 0 3 3 3 2 Response regulator receiver domain PAS_9 PF13426.1 ETS85099.1 - 1.7e-16 60.4 0.0 1.2e-09 38.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 ETS85099.1 - 1.8e-13 50.4 0.0 1.3e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 ETS85099.1 - 3.2e-13 49.5 1.7 1.3e-06 28.3 0.1 3.7 3 1 0 3 3 3 2 PAS fold PAS PF00989.19 ETS85099.1 - 5.3e-09 35.8 0.0 2.2e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 ETS85099.1 - 8.7e-08 32.0 1.0 2.2e-07 30.7 0.0 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 ETS85099.1 - 0.00028 20.6 0.0 0.0064 16.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain DUF1828 PF08861.5 ETS85099.1 - 0.028 14.0 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1828 PAS_11 PF14598.1 ETS85099.1 - 0.064 13.2 0.0 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 PAS domain Flavokinase PF01687.12 ETS85100.1 - 5.5e-13 48.8 0.0 9.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase APG17 PF04108.7 ETS85101.1 - 1.3e-104 350.2 9.1 1.6e-104 350.0 6.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 LOH1CR12 PF10158.4 ETS85101.1 - 0.0041 16.9 4.1 0.039 13.7 0.2 3.2 4 0 0 4 4 4 1 Tumour suppressor protein RmuC PF02646.11 ETS85101.1 - 0.013 14.3 5.1 0.19 10.5 0.2 3.9 3 1 0 3 3 3 0 RmuC family DUF2209 PF09974.4 ETS85101.1 - 0.051 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Laminin_II PF06009.7 ETS85101.1 - 0.13 11.9 9.2 0.15 11.8 0.4 3.5 3 1 1 4 4 4 0 Laminin Domain II Cep57_MT_bd PF06657.8 ETS85101.1 - 0.14 12.0 8.4 0.79 9.7 0.4 4.3 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF972 PF06156.8 ETS85101.1 - 0.4 11.0 5.9 4 7.8 0.5 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF972) Troponin PF00992.15 ETS85101.1 - 1.3 9.1 7.3 0.094 12.7 0.5 2.4 2 0 0 2 2 2 0 Troponin Hemerythrin PF01814.18 ETS85101.1 - 1.7 8.7 9.3 21 5.2 0.4 4.5 2 2 1 3 3 3 0 Hemerythrin HHE cation binding domain Fib_alpha PF08702.5 ETS85101.1 - 5 7.2 8.3 8.4 6.5 0.6 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.9 ETS85102.1 - 0.012 14.9 3.9 0.19 11.1 0.3 3.0 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Matrilin_ccoil PF10393.4 ETS85102.1 - 0.029 13.7 14.5 0.36 10.2 0.1 5.8 4 2 1 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4381 PF14316.1 ETS85102.1 - 0.035 14.2 1.2 0.12 12.4 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) AAA_13 PF13166.1 ETS85102.1 - 0.04 12.4 16.2 0.064 11.7 11.1 1.4 1 1 0 1 1 1 0 AAA domain BatA PF07584.6 ETS85102.1 - 0.075 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF3007 PF11460.3 ETS85102.1 - 0.11 12.5 0.3 0.11 12.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF1664 PF07889.7 ETS85102.1 - 0.18 11.6 13.3 0.96 9.2 1.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 ETS85102.1 - 0.19 10.8 4.5 0.37 9.9 3.1 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Sec34 PF04136.10 ETS85102.1 - 0.43 10.2 5.0 0.66 9.6 0.3 2.4 2 0 0 2 2 2 0 Sec34-like family IncA PF04156.9 ETS85102.1 - 0.76 9.3 23.2 0.042 13.4 2.5 3.0 2 1 0 2 2 2 0 IncA protein CagA PF03507.8 ETS85102.1 - 0.91 9.3 5.8 0.15 11.9 0.8 2.0 2 1 0 2 2 2 0 CagA exotoxin ABC_tran PF00005.22 ETS85102.1 - 1 9.6 8.4 2.1 8.6 0.2 2.6 1 1 1 2 2 2 0 ABC transporter DASH_Duo1 PF08651.5 ETS85102.1 - 1.4 8.5 7.4 0.81 9.2 0.2 3.5 3 1 1 4 4 4 0 DASH complex subunit Duo1 DUF155 PF02582.9 ETS85102.1 - 2 8.3 7.1 1.9 8.3 3.4 2.0 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 SelB-wing_1 PF09105.5 ETS85102.1 - 2.6 7.7 5.6 5.1 6.8 0.2 3.0 4 0 0 4 4 3 0 Elongation factor SelB, winged helix Fib_alpha PF08702.5 ETS85102.1 - 2.9 8.0 17.3 0.07 13.2 1.4 3.2 2 1 1 4 4 3 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.4 ETS85102.1 - 5.8 6.5 10.4 2.8 7.5 0.2 4.3 2 2 3 5 5 5 0 Predicted coiled-coil protein (DUF2205) SlyX PF04102.7 ETS85102.1 - 7.2 7.0 23.1 1.4 9.3 0.6 5.0 2 1 3 5 5 5 0 SlyX AMP-binding PF00501.23 ETS85103.1 - 7.5e-58 195.8 0.0 1.9e-57 194.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 ETS85103.1 - 2e-13 50.4 0.0 5.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 ETS85103.1 - 2.2e-07 30.0 16.6 0.00083 18.7 0.0 6.9 8 0 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 ETS85103.1 - 0.034 13.7 15.6 6.7 6.3 0.0 6.4 4 3 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase Mpv17_PMP22 PF04117.7 ETS85106.1 - 6e-19 67.4 0.1 1.2e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 ETS85107.1 - 2.5e-40 138.3 31.6 5.8e-40 137.0 21.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 ETS85108.1 - 1.1e-49 168.8 0.0 1.2e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_22 PF13309.1 ETS85108.1 - 0.12 12.1 0.0 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 HTH domain PseudoU_synth_1 PF01416.15 ETS85109.1 - 2.9e-21 75.8 0.2 9.4e-10 38.8 0.1 2.8 2 1 1 3 3 3 2 tRNA pseudouridine synthase IFT57 PF10498.4 ETS85109.1 - 0.24 10.0 6.5 0.42 9.3 4.5 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CAML PF14963.1 ETS85109.1 - 6.4 6.0 11.7 0.18 11.1 3.4 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Mucin PF01456.12 ETS85109.1 - 7.9 6.2 11.4 16 5.2 7.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Med22 PF06179.7 ETS85110.1 - 2.7e-10 40.2 0.3 3.3e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Gon7 PF08738.5 ETS85110.1 - 0.063 13.2 1.0 0.083 12.8 0.3 1.5 2 0 0 2 2 2 0 Gon7 family Pyr_redox_2 PF07992.9 ETS85111.1 - 1e-13 51.6 0.0 4.3e-13 49.5 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS85111.1 - 4.4e-13 49.4 0.0 3.4e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS85111.1 - 1.2e-08 35.2 0.2 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS85111.1 - 1.8e-07 30.4 0.1 0.0002 20.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 ETS85111.1 - 0.034 14.4 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 ETS85111.1 - 0.034 14.1 0.0 4.7 7.2 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_9 PF13454.1 ETS85111.1 - 0.034 13.9 1.3 4 7.1 0.0 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS85111.1 - 0.062 12.2 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 ETS85111.1 - 0.42 9.1 2.8 4.3 5.8 0.0 3.0 3 1 1 4 4 4 0 Tryptophan halogenase Cerato-platanin PF07249.7 ETS85112.1 - 5.4e-07 29.6 0.3 2.2e-06 27.6 0.2 2.1 1 0 0 1 1 1 1 Cerato-platanin adh_short PF00106.20 ETS85113.1 - 0.00062 19.7 0.1 0.00063 19.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldolase PF01081.14 ETS85113.1 - 0.0086 15.2 0.3 0.01 15.0 0.2 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase DUF2173 PF09941.4 ETS85113.1 - 0.024 14.5 0.4 0.03 14.2 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Pyr_redox PF00070.22 ETS85113.1 - 0.099 13.0 0.2 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS85113.1 - 0.15 12.2 0.3 0.2 11.9 0.2 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding UbiA PF01040.13 ETS85114.1 - 3.8e-18 65.6 18.9 1.1e-17 64.1 13.1 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family Zn_clus PF00172.13 ETS85115.1 - 7.8e-11 41.7 5.8 1.8e-10 40.5 4.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferritin PF00210.19 ETS85115.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain Peptidase_M20 PF01546.23 ETS85116.1 - 3.5e-07 29.9 0.3 6.1e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS85116.1 - 3.7e-06 26.6 0.0 8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.18 ETS85118.1 - 1.7e-15 57.4 0.0 2.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS85118.1 - 3.1e-05 23.6 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETS85118.1 - 0.01 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 ETS85118.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain PI3_PI4_kinase PF00454.22 ETS85118.1 - 0.027 13.9 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Fructosamin_kin PF03881.9 ETS85118.1 - 0.042 12.8 0.2 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 ETS85118.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 ETS85118.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.21 ETS85120.1 - 1.5e-25 89.2 1.0 2.9e-25 88.2 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS85120.1 - 2.7e-22 78.5 0.4 6.1e-22 77.4 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS85120.1 - 3.4e-06 27.9 0.0 8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CorA PF01544.13 ETS85122.1 - 0.031 13.3 0.5 0.041 12.9 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_14 PF13173.1 ETS85122.1 - 0.09 12.6 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Tricorn_C1 PF14684.1 ETS85122.1 - 0.1 12.4 0.2 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain Glyco_transf_28 PF03033.15 ETS85123.1 - 2.4e-23 82.4 0.2 4.9e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS85123.1 - 0.00022 19.9 0.0 0.00036 19.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 ETS85123.1 - 0.0095 16.0 0.4 0.097 12.8 0.0 2.7 3 0 0 3 3 3 1 ATG C terminal domain DUF515 PF04415.7 ETS85123.1 - 0.49 8.5 2.3 0.76 7.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.6 ETS85123.1 - 5 5.0 4.1 6.8 4.6 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MARVEL PF01284.18 ETS85124.1 - 0.0032 17.2 19.0 0.1 12.4 13.2 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF3169 PF11368.3 ETS85124.1 - 0.24 10.5 3.7 0.48 9.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) PRA1 PF03208.14 ETS85124.1 - 2.5 7.4 10.0 1.9 7.8 4.6 2.1 1 1 1 2 2 2 0 PRA1 family protein Bac_rhamnosid PF05592.6 ETS85125.1 - 3.8e-22 78.1 2.3 3.8e-15 55.0 0.6 2.6 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 ETS85125.1 - 0.00077 18.2 0.6 0.0012 17.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 ETS85125.1 - 0.0024 16.5 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase AflR PF08493.5 ETS85126.1 - 3.6e-09 36.0 7.1 5.6e-09 35.4 4.9 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 ETS85126.1 - 9.5e-08 31.8 10.9 2.6e-07 30.4 7.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.12 ETS85127.1 - 6.1e-23 81.2 10.3 8e-23 80.9 7.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sugar_tr PF00083.19 ETS85129.1 - 4.6e-66 223.2 16.9 5.2e-66 223.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2985 PF11204.3 ETS85129.1 - 0.0058 16.3 3.3 0.62 9.8 0.3 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2985) Cation_efflux PF01545.16 ETS85129.1 - 0.18 10.8 2.8 0.17 10.9 0.5 1.9 1 1 1 2 2 2 0 Cation efflux family DUF1201 PF06716.6 ETS85129.1 - 0.36 10.6 3.9 0.19 11.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) NfeD PF01957.13 ETS85129.1 - 0.8 9.8 0.0 0.8 9.8 0.0 2.8 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 ETS85129.1 - 1.9 7.8 11.8 2.1 7.7 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HCO3_cotransp PF00955.16 ETS85130.1 - 1.2e-54 185.9 15.6 1.9e-34 119.2 4.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family HnRNP_M PF11532.3 ETS85131.1 - 3.8 7.6 5.5 1.5 8.9 1.5 2.1 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M HET PF06985.6 ETS85132.1 - 7.4e-33 113.6 2.2 1.1e-32 113.0 1.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS85133.1 - 6.2e-30 104.1 0.0 9.9e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Linker_histone PF00538.14 ETS85134.1 - 3.9e-06 26.8 0.1 1e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.6 ETS85134.1 - 0.13 12.0 74.3 0.17 11.7 51.5 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Gti1_Pac2 PF09729.4 ETS85136.1 - 1.5e-49 168.0 3.1 1.7e-47 161.4 2.2 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 ETS85137.1 - 2.2e-71 240.3 0.0 2.9e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 ETS85137.1 - 2.6e-05 23.9 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.4 ETS85138.1 - 1.9e-15 57.1 0.0 3.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SR-25 PF10500.4 ETS85138.1 - 4.6 6.6 14.2 7 6.0 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec23_trunk PF04811.10 ETS85139.1 - 1.9e-51 174.7 0.0 3.2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS85139.1 - 1.1e-25 88.9 0.0 2.1e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 ETS85139.1 - 4.1e-17 62.4 0.0 1.1e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 ETS85139.1 - 8.2e-07 28.6 0.0 1.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 ETS85139.1 - 0.00042 19.8 0.1 0.00092 18.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Beta-Casp PF10996.3 ETS85141.1 - 2.1e-27 95.5 0.0 4.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.1 ETS85141.1 - 9.2e-25 87.7 0.1 7.3e-18 65.2 0.0 2.8 1 1 1 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 ETS85141.1 - 0.00044 19.9 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Glyco_hydro_43 PF04616.9 ETS85142.1 - 2.1e-13 50.0 7.6 1.9e-11 43.5 1.6 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Methyltransf_23 PF13489.1 ETS85143.1 - 1.1e-18 67.5 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS85143.1 - 1.2e-10 41.1 0.0 3.5e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS85143.1 - 2.1e-08 34.7 0.0 2.6e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85143.1 - 3.9e-08 33.6 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS85143.1 - 7.8e-05 23.0 0.0 0.00018 21.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS85143.1 - 0.00019 21.7 0.0 0.0004 20.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS85143.1 - 0.0015 17.7 0.0 0.006 15.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 ETS85143.1 - 0.013 14.5 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 ETS85143.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 ETS85143.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 ETS85143.1 - 0.023 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 ETS85143.1 - 0.07 12.6 0.0 0.45 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 ETS85143.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Ank_2 PF12796.2 ETS85144.1 - 5e-09 36.3 0.0 1.9e-05 24.9 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85144.1 - 1.8e-08 33.7 0.1 0.00021 20.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 ETS85144.1 - 9.6e-06 25.9 0.1 0.011 16.2 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS85144.1 - 3.2e-05 24.0 0.0 0.0028 17.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85144.1 - 5.8e-05 22.9 3.9 0.0038 17.3 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat AAA_12 PF13087.1 ETS85145.1 - 6.8e-20 71.2 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS85145.1 - 5.4e-11 42.5 0.0 1.6e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS85145.1 - 1e-07 31.7 0.0 0.00025 20.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS85145.1 - 6.6e-05 22.5 0.2 0.00028 20.5 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 ETS85145.1 - 0.00029 20.4 0.0 1.1 8.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF605 PF04652.11 ETS85145.1 - 4.8 6.4 35.1 0.083 12.2 19.6 1.4 2 0 0 2 2 2 0 Vta1 like DUF1664 PF07889.7 ETS85146.1 - 0.12 12.1 19.7 0.12 12.2 1.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF2802 PF10975.3 ETS85146.1 - 0.33 10.7 4.2 0.78 9.5 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Reo_sigmaC PF04582.7 ETS85146.1 - 1.6 7.8 11.8 3 6.9 1.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fzo_mitofusin PF04799.8 ETS85146.1 - 8.6 5.7 17.5 4.2 6.7 0.1 3.8 2 2 2 4 4 4 0 fzo-like conserved region zf-C2H2 PF00096.21 ETS85147.1 - 3.2e-28 96.3 54.7 0.00015 21.9 1.3 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS85147.1 - 3.4e-23 80.1 48.4 0.00015 21.8 3.2 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS85147.1 - 6.2e-13 48.3 68.7 0.00063 19.9 1.0 8.8 9 0 0 9 9 9 7 Zinc-finger double domain zf-met PF12874.2 ETS85147.1 - 8.6e-05 22.6 19.2 0.96 9.7 0.0 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type Cu-oxidase_2 PF07731.9 ETS85148.1 - 3.2e-40 136.8 6.1 1.1e-38 131.8 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS85148.1 - 1.1e-37 128.3 1.2 1.1e-37 128.3 0.9 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS85148.1 - 4.5e-36 124.1 0.1 5.5e-34 117.3 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Terminase_4 PF05119.7 ETS85148.1 - 0.024 14.7 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 Phage terminase, small subunit Dispanin PF04505.7 ETS85149.1 - 0.011 15.2 0.3 0.026 14.0 0.2 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein adh_short PF00106.20 ETS85150.1 - 1.6e-20 73.7 0.1 2.3e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85150.1 - 4.9e-07 29.7 0.0 7.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS85150.1 - 1.2e-05 25.3 0.3 2.2e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS85150.1 - 0.00014 21.5 0.2 0.0026 17.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS85150.1 - 0.00089 18.7 0.1 0.048 13.0 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETS85150.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 ETS85150.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC_tran PF00005.22 ETS85151.1 - 6.2e-39 133.4 0.1 7.3e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS85151.1 - 3.1e-38 131.7 5.0 4.8e-38 131.1 3.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 ETS85151.1 - 4e-10 39.3 0.3 0.0026 17.0 0.1 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS85151.1 - 5.4e-08 33.1 0.0 0.00039 20.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 ETS85151.1 - 1.5e-05 23.7 0.1 0.0058 15.2 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class ABC_membrane_3 PF13748.1 ETS85151.1 - 0.00016 20.7 0.2 0.0003 19.8 0.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_25 PF13481.1 ETS85151.1 - 0.00019 20.9 0.9 0.11 11.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 ETS85151.1 - 0.00021 21.1 0.2 0.17 11.8 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 ETS85151.1 - 0.00091 18.8 0.1 0.14 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 ETS85151.1 - 0.0011 19.1 1.1 0.043 13.9 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 ETS85151.1 - 0.0017 19.1 0.1 0.011 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS85151.1 - 0.0021 18.0 4.0 0.023 14.6 1.7 3.1 3 1 0 3 3 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 ETS85151.1 - 0.0091 15.5 0.1 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 ETS85151.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 ETS85151.1 - 0.016 15.0 0.0 0.39 10.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 ETS85151.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS85151.1 - 0.034 14.3 0.3 15 5.7 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 ETS85151.1 - 0.034 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 ETS85151.1 - 0.049 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETS85151.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KGG PF10685.4 ETS85152.1 - 0.01 15.7 19.1 0.057 13.3 4.5 2.9 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif MFS_1 PF07690.11 ETS85153.1 - 2.1e-30 105.6 26.8 2.1e-30 105.6 18.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Tyrosinase PF00264.15 ETS85154.1 - 1.7e-21 77.3 0.5 2.7e-21 76.7 0.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 ETS85156.1 - 8.7e-45 152.9 50.2 5.6e-44 150.2 34.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS85156.1 - 1.3e-17 63.3 14.2 1.3e-17 63.3 9.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS85156.1 - 6.9e-11 41.3 32.1 6.4e-10 38.1 8.8 3.4 2 1 1 3 3 3 3 Sugar (and other) transporter DUF3632 PF12311.3 ETS85158.1 - 1.2e-25 90.4 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Invas_SpaK PF03519.9 ETS85158.1 - 0.0017 18.1 0.0 0.0066 16.2 0.0 1.9 2 0 0 2 2 2 1 Invasion protein B family zf-RING_2 PF13639.1 ETS85159.1 - 2e-10 40.3 12.4 9.8e-10 38.1 8.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS85159.1 - 4.6e-07 29.4 7.8 4.6e-07 29.4 5.4 2.8 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS85159.1 - 1.3e-06 28.3 7.8 1.3e-06 28.3 5.4 3.2 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS85159.1 - 4.5e-06 26.2 10.5 4.5e-06 26.2 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS85159.1 - 4.7e-06 26.2 8.2 4.7e-06 26.2 5.7 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 ETS85159.1 - 1.2e-05 25.3 6.6 1.2e-05 25.3 4.6 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 ETS85159.1 - 0.0028 17.3 12.5 0.0046 16.6 5.3 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-Apc11 PF12861.2 ETS85159.1 - 0.0074 16.1 5.8 0.022 14.5 4.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 ETS85159.1 - 0.013 15.0 9.1 0.018 14.5 5.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 ETS85159.1 - 0.02 14.4 3.5 0.02 14.4 2.4 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 ETS85159.1 - 0.043 13.5 2.3 0.15 11.8 1.6 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 ETS85159.1 - 0.058 13.2 9.8 0.77 9.6 6.9 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.16 ETS85159.1 - 1.8 8.5 13.9 4.6 7.1 6.3 3.0 2 1 1 3 3 3 0 IBR domain Peptidase_A4 PF01828.12 ETS85160.1 - 6.8e-90 299.6 14.9 8e-90 299.4 10.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF588 PF04535.7 ETS85160.1 - 0.16 11.5 2.0 0.34 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF588) HHH_8 PF14716.1 ETS85161.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain LrgB PF04172.11 ETS85163.1 - 8e-27 93.7 10.8 8e-27 93.7 7.5 2.5 2 1 0 2 2 2 1 LrgB-like family ADP_ribosyl_GH PF03747.9 ETS85163.1 - 0.0032 17.2 0.2 0.0054 16.5 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1614 PF07758.6 ETS85163.1 - 6.8 6.3 14.6 0.081 12.6 3.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1614) BRCT PF00533.21 ETS85164.1 - 8.1e-16 57.9 0.0 6.3e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain REC114-like PF15165.1 ETS85164.1 - 0.044 13.5 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like NOA36 PF06524.7 ETS85164.1 - 3 7.0 8.0 7.2 5.7 5.5 1.6 1 0 0 1 1 1 0 NOA36 protein NAD_binding_10 PF13460.1 ETS85165.1 - 1.4e-27 96.8 0.1 1.7e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS85165.1 - 7e-08 32.1 0.0 9.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS85165.1 - 1.2e-07 31.2 0.2 2.5e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 ETS85165.1 - 9.1e-06 24.7 0.9 0.0057 15.6 0.1 2.1 1 1 0 2 2 2 2 Male sterility protein DapB_N PF01113.15 ETS85165.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 ETS85165.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 ETS85165.1 - 0.06 12.9 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 ETS85165.1 - 0.067 13.1 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 ETS85165.1 - 0.11 12.3 1.0 0.5 10.2 0.7 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Abhydrolase_6 PF12697.2 ETS85166.1 - 2.5e-21 76.6 0.0 6.1e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85166.1 - 2e-10 40.6 0.2 5.6e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85166.1 - 5.7e-08 32.5 0.2 0.003 17.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Beta-lactamase PF00144.19 ETS85167.1 - 2e-28 99.3 0.1 3.8e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase HET PF06985.6 ETS85168.1 - 1.1e-11 45.0 0.0 2.5e-10 40.6 0.0 2.7 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Methyltransf_8 PF05148.10 ETS85168.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Tannase PF07519.6 ETS85169.1 - 1.3e-81 274.7 0.5 1.6e-81 274.4 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS85169.1 - 5.3e-06 26.4 0.1 2.1e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS85169.1 - 0.0048 16.1 0.2 0.42 9.7 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS85169.1 - 0.0054 16.4 1.3 0.28 10.9 0.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85169.1 - 0.026 14.1 2.1 0.052 13.0 1.5 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 ETS85170.1 - 9.3e-06 24.4 0.0 2.5e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS85171.1 - 5.2e-20 71.4 39.3 5.2e-20 71.4 27.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Tyrosinase PF00264.15 ETS85172.1 - 1.7e-40 139.5 0.6 2.1e-40 139.2 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans_2 PF11951.3 ETS85173.1 - 0.0091 14.6 0.1 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AATase PF07247.7 ETS85174.1 - 1.4e-14 53.5 0.0 3.5e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Peptidase_S9 PF00326.16 ETS85175.1 - 3.3e-44 150.6 0.1 5.5e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS85175.1 - 1.2e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 ETS85175.1 - 3.7e-10 39.4 0.1 8.9e-09 34.9 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 ETS85175.1 - 3.2e-09 36.8 0.0 1.1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 ETS85175.1 - 7.5e-08 32.1 0.4 0.022 14.1 0.9 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.7 ETS85175.1 - 7.5e-07 28.6 1.0 0.0014 18.2 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 ETS85175.1 - 7.9e-07 29.1 0.0 2.8e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS85175.1 - 3.5e-05 23.4 0.0 7.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 ETS85175.1 - 3.7e-05 23.3 0.0 0.044 13.3 0.0 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 ETS85175.1 - 0.00017 21.0 0.0 0.00055 19.4 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.15 ETS85175.1 - 0.00087 18.7 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 ETS85175.1 - 0.00098 17.7 0.2 0.002 16.6 0.1 1.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.5 ETS85175.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein PAE PF03283.8 ETS85175.1 - 0.014 14.0 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase SprT-like PF10263.4 ETS85177.1 - 0.00079 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family CHAT PF12770.2 ETS85180.1 - 1.4e-26 93.3 0.0 2.6e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 ETS85180.1 - 0.011 15.6 0.1 0.036 13.9 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85180.1 - 0.039 13.5 0.3 0.086 12.4 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85180.1 - 0.075 12.8 0.1 0.26 11.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HAD PF12710.2 ETS85181.1 - 2.9e-05 24.3 0.0 4.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 ETS85182.1 - 6.9e-70 235.8 0.0 8.8e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GTPase_Cys_C PF12631.2 ETS85183.1 - 0.024 15.0 0.7 0.37 11.2 0.0 2.8 3 1 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Tyrosinase PF00264.15 ETS85184.1 - 4e-35 121.9 5.7 5.6e-35 121.5 4.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Kelch_1 PF01344.20 ETS85185.1 - 2.4e-31 107.0 9.9 1.3e-10 40.6 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 ETS85185.1 - 4.2e-29 99.4 13.9 1.9e-10 40.4 0.1 6.9 2 2 5 7 7 7 6 Kelch motif Kelch_3 PF13415.1 ETS85185.1 - 1.3e-28 98.4 17.5 5.1e-07 29.6 0.0 6.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS85185.1 - 8.1e-25 86.3 10.8 9.1e-05 22.1 0.1 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS85185.1 - 1.2e-13 50.7 5.6 0.0048 16.8 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 ETS85185.1 - 5.9e-11 41.6 4.7 0.027 14.2 0.1 6.1 6 1 0 6 6 6 2 Kelch motif DUF1668 PF07893.8 ETS85185.1 - 0.03 13.4 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) E1-E2_ATPase PF00122.15 ETS85186.1 - 7.5e-49 165.8 0.3 7.5e-49 165.8 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS85186.1 - 4.4e-41 140.4 9.4 4.4e-41 140.4 6.5 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS85186.1 - 8.6e-31 108.0 0.0 2e-30 106.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS85186.1 - 5.6e-18 64.6 0.0 1.1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 ETS85186.1 - 5.1e-13 49.6 0.2 2.8e-12 47.2 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS85186.1 - 2.5e-12 46.0 0.0 1.2e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 ETS85186.1 - 0.00057 19.5 0.5 0.0011 18.6 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.4 ETS85186.1 - 0.093 12.3 4.8 1.2 8.7 0.6 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) MFS_1 PF07690.11 ETS85187.1 - 1.4e-28 99.6 26.5 1.4e-28 99.6 18.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85187.1 - 1.4e-10 40.4 23.2 4.1e-10 38.8 16.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MMPL PF03176.10 ETS85188.1 - 0.14 10.8 0.0 0.15 10.6 0.0 1.0 1 0 0 1 1 1 0 MMPL family PhyH PF05721.8 ETS85189.1 - 9.8e-08 32.2 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 ETS85189.1 - 0.017 13.6 0.1 1.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.13 ETS85190.1 - 3.2e-35 121.8 0.1 8.7e-33 113.8 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS85190.1 - 3e-29 102.4 0.0 4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS85190.1 - 6.5e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.2 ETS85191.1 - 0.003 17.2 0.1 0.0064 16.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S15 PF02129.13 ETS85192.1 - 9.5e-40 136.7 0.2 1.6e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS85192.1 - 3.5e-34 118.6 0.1 5e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS85192.1 - 2.3e-05 24.4 0.1 4.9e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85192.1 - 0.00018 21.3 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS85192.1 - 0.002 17.9 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Bac_small_YrzI PF09501.5 ETS85192.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Aldedh PF00171.17 ETS85193.1 - 3.5e-17 61.8 0.1 3e-11 42.3 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Peptidase_S15 PF02129.13 ETS85194.1 - 9e-46 156.4 0.1 1.1e-42 146.3 0.0 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 ETS85194.1 - 3.5e-23 82.6 0.0 4.7e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 ETS85194.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 ETS85195.1 - 0.052 13.3 0.2 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Cupin_2 PF07883.6 ETS85196.1 - 7.2e-07 28.6 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 ETS85196.1 - 0.054 12.8 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) LigB PF02900.13 ETS85198.1 - 6.3e-23 81.1 0.1 7.5e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FAD_binding_3 PF01494.14 ETS85199.1 - 2.1e-19 69.7 0.0 3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85199.1 - 1.9e-08 33.5 0.6 8.8e-05 21.5 1.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85199.1 - 2.1e-06 27.6 0.5 6e-06 26.2 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS85199.1 - 0.00013 21.9 0.1 0.00021 21.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS85199.1 - 0.0002 20.3 1.9 0.0003 19.7 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 ETS85199.1 - 0.00023 19.9 0.7 0.019 13.6 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 ETS85199.1 - 0.0025 16.7 0.4 0.0036 16.2 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS85199.1 - 0.0035 16.4 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS85199.1 - 0.0081 14.6 0.6 0.019 13.4 0.6 1.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 ETS85199.1 - 0.02 14.4 0.3 0.032 13.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS85199.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS85199.1 - 0.057 12.4 0.3 2.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 ETS85199.1 - 0.06 13.7 1.2 0.15 12.4 0.8 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS85199.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 ETS85199.1 - 0.15 10.9 0.2 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 ETS85199.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 ETS85200.1 - 1.1e-61 208.8 0.0 1.4e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 ETS85201.1 - 5.6e-18 65.1 1.3 1.1e-17 64.1 0.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCCH PF00642.19 ETS85202.1 - 1.2e-05 24.8 3.1 2.4e-05 23.9 2.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 ETS85202.1 - 0.47 10.5 3.2 1.4 9.0 2.2 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Nucleoporin_FG PF13634.1 ETS85202.1 - 1.2 9.3 166.7 27 5.0 2.8 6.3 2 1 2 4 4 4 0 Nucleoporin FG repeat region Ribosomal_S10 PF00338.17 ETS85203.1 - 1.4e-28 98.6 0.7 1.7e-28 98.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 ETS85204.1 - 1.4e-09 37.2 0.4 2.4e-09 36.4 0.3 1.5 1 0 0 1 1 1 1 CUE domain API5 PF05918.6 ETS85204.1 - 7.5 4.9 11.5 6.2 5.1 0.0 2.5 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) NmrA PF05368.8 ETS85206.1 - 3.8e-28 98.3 0.1 4.7e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS85206.1 - 3e-13 50.1 1.0 5.1e-13 49.4 0.6 1.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS85206.1 - 8.5e-07 28.2 0.2 1.2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 ETS85206.1 - 5.3e-05 22.7 0.1 0.00011 21.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS85206.1 - 0.00046 19.1 0.1 0.00069 18.6 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_2 PF03446.10 ETS85206.1 - 0.01 15.6 0.2 0.038 13.8 0.1 1.9 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETS85206.1 - 0.035 13.5 0.5 1.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.19 ETS85206.1 - 0.047 13.9 0.3 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoatB PF10389.4 ETS85206.1 - 0.074 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage coat protein B RmlD_sub_bind PF04321.12 ETS85206.1 - 0.079 11.8 0.2 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2235 PF09994.4 ETS85206.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DXP_reductoisom PF02670.11 ETS85206.1 - 0.44 11.0 4.1 21 5.6 0.1 3.1 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PepSY_TM_1 PF13172.1 ETS85207.1 - 0.009 15.7 1.1 0.036 13.8 0.3 2.2 2 0 0 2 2 2 1 PepSY-associated TM helix ApbA PF02558.11 ETS85209.1 - 3.1e-30 104.6 0.2 4.3e-30 104.1 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 ETS85209.1 - 1e-27 96.6 0.0 2.2e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.17 ETS85209.1 - 0.004 17.6 0.4 0.016 15.7 0.0 2.0 1 1 1 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 ETS85209.1 - 0.015 15.1 1.1 0.029 14.1 0.4 1.7 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 ETS85209.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.7 1 1 1 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 ETS85209.1 - 0.045 13.1 0.6 0.65 9.3 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 ETS85209.1 - 0.06 13.4 0.3 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cutinase PF01083.17 ETS85210.1 - 1.1e-46 158.8 2.0 1.3e-46 158.6 1.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS85210.1 - 0.00025 20.5 0.2 0.00035 20.0 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 ETS85210.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 ETS85210.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 ETS85210.1 - 0.0072 15.7 0.5 0.017 14.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 ETS85210.1 - 0.019 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LacAB_rpiB PF02502.13 ETS85210.1 - 0.087 12.4 0.9 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Oxidored_FMN PF00724.15 ETS85211.1 - 1e-90 304.2 0.0 1.2e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RelB PF04221.7 ETS85211.1 - 0.045 13.4 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 RelB antitoxin AP_endonuc_2 PF01261.19 ETS85211.1 - 0.072 12.3 0.0 5.4 6.2 0.0 2.8 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel DIM1 PF02966.11 ETS85211.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 ABC2_membrane PF01061.19 ETS85212.1 - 2e-53 180.7 50.0 1.7e-27 96.0 12.9 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS85212.1 - 5.4e-34 117.4 0.4 3.8e-16 59.6 0.0 3.0 4 0 0 4 4 2 2 ABC transporter PDR_CDR PF06422.7 ETS85212.1 - 9.5e-28 95.8 1.2 1.4e-20 72.8 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter AAA_25 PF13481.1 ETS85212.1 - 1.6e-06 27.6 0.1 0.038 13.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS85212.1 - 6.7e-06 25.3 0.1 0.00033 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETS85212.1 - 0.00021 21.3 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS85212.1 - 0.0005 20.1 0.2 0.058 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETS85212.1 - 0.00055 19.4 0.3 0.026 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 ETS85212.1 - 0.0011 18.5 1.8 0.14 11.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 ETS85212.1 - 0.0016 18.7 0.3 0.53 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS85212.1 - 0.004 17.0 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 ETS85212.1 - 0.0051 16.7 2.1 1.7 8.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 ETS85212.1 - 0.011 15.4 1.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 ETS85212.1 - 0.011 15.8 1.2 2.4 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 ETS85212.1 - 0.012 15.1 0.8 1.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 ETS85212.1 - 0.021 15.6 0.2 2.7 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS85212.1 - 0.025 14.3 1.3 7.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 ETS85212.1 - 0.056 13.0 0.7 3.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 ETS85212.1 - 0.066 11.9 0.4 0.56 8.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein ABC_trans_N PF14510.1 ETS85212.1 - 0.086 12.9 0.8 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal AAA_15 PF13175.1 ETS85212.1 - 0.12 11.4 0.0 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 ETS85212.1 - 0.14 12.1 0.1 22 5.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 ETS85212.1 - 0.21 11.2 1.1 5.6 6.6 0.1 2.8 3 0 0 3 3 3 0 NTPase Arf PF00025.16 ETS85212.1 - 0.28 10.4 0.2 20 4.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 ETS85212.1 - 0.37 10.4 0.0 22 4.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 ETS85212.1 - 0.67 8.8 2.3 2 7.2 0.3 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Fungal_trans PF04082.13 ETS85213.1 - 1.3e-15 56.9 0.2 1.9e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85213.1 - 5.2e-09 35.8 7.6 1.3e-08 34.6 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfotransfer_3 PF13469.1 ETS85214.1 - 1.6e-05 25.8 0.5 3.1e-05 24.9 0.3 1.4 1 1 0 1 1 1 1 Sulfotransferase family Amidohydro_2 PF04909.9 ETS85215.1 - 5.8e-44 150.6 0.0 7.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Dioxygenase_C PF00775.16 ETS85216.1 - 1.5e-09 37.3 0.0 4.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase BTB PF00651.26 ETS85218.1 - 3.4e-13 49.5 0.0 8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_L-PSP PF01042.16 ETS85219.1 - 3.3e-22 78.5 0.0 3.6e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Chol_subst-bind PF09129.6 ETS85219.1 - 0.024 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Isochorismatase PF00857.15 ETS85221.1 - 1.3e-22 80.5 0.3 7.1e-22 78.1 0.2 1.9 1 1 0 1 1 1 1 Isochorismatase family C1-set PF07654.10 ETS85223.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Tubulin PF00091.20 ETS85224.1 - 2.3e-64 217.1 0.0 5e-64 216.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS85224.1 - 6.4e-28 97.3 0.0 9.8e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETS85224.1 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 ETS85224.1 - 0.076 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain F-box-like PF12937.2 ETS85226.1 - 2.8e-06 26.9 0.0 7.7e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS85226.1 - 0.0085 15.7 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 ETS85226.1 - 10 5.8 5.9 4.2 7.0 0.0 3.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF4126 PF13548.1 ETS85227.1 - 0.027 13.9 0.9 0.033 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) MRJP PF03022.11 ETS85228.1 - 6.4e-29 101.0 0.0 1.2e-28 100.1 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 ETS85228.1 - 0.00017 21.0 0.0 0.0031 16.9 0.0 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 ETS85228.1 - 0.014 14.8 0.1 0.051 13.0 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain NHL PF01436.16 ETS85228.1 - 0.02 14.8 1.5 38 4.5 0.0 4.2 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.6 ETS85228.1 - 0.029 14.3 2.0 32 5.0 0.0 4.4 4 0 0 4 4 4 0 Two component regulator propeller PD40 PF07676.7 ETS85228.1 - 0.042 13.5 0.5 3.8 7.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Fungal_trans PF04082.13 ETS85230.1 - 1.2e-14 53.8 0.4 1.8e-14 53.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85230.1 - 1.5e-08 34.4 14.0 3.3e-08 33.2 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 ETS85231.1 - 1.1e-39 136.1 59.3 1.1e-39 136.1 41.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 ETS85232.1 - 5.1e-27 94.6 2.4 7.9e-27 94.0 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AA_permease PF00324.16 ETS85235.1 - 4e-125 417.8 30.9 4.8e-125 417.6 21.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS85235.1 - 1.5e-33 115.9 34.4 1.9e-33 115.6 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease Asp PF00026.18 ETS85236.1 - 1e-58 199.0 4.5 1.5e-58 198.5 3.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS85236.1 - 3.5e-06 27.0 0.1 3.5e-06 27.0 0.0 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Fungal_trans_2 PF11951.3 ETS85237.1 - 0.013 14.1 0.1 0.02 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DNA_ligase_A_M PF01068.16 ETS85238.1 - 7e-49 165.9 0.2 2.4e-46 157.6 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 ETS85238.1 - 5.4e-41 140.3 0.0 1.1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 ETS85238.1 - 3.8e-19 68.8 0.0 4e-11 43.1 0.0 3.3 2 1 1 3 3 3 2 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.15 ETS85239.1 - 7.2e-60 202.6 0.0 9.2e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Lysozyme_like PF13702.1 ETS85240.1 - 0.0093 15.4 0.3 0.037 13.4 0.2 1.9 1 1 0 1 1 1 1 Lysozyme-like DUF1509 PF07420.6 ETS85240.1 - 0.4 9.8 12.0 0.28 10.4 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1509) DUF3767 PF12597.3 ETS85241.1 - 4.1e-35 119.9 0.1 4.1e-35 119.9 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.7 ETS85241.1 - 0.0069 15.7 0.3 0.0092 15.3 0.2 1.1 1 0 0 1 1 1 1 5TMR of 5TMR-LYT DUF1744 PF08490.7 ETS85242.1 - 2.5e-155 516.9 0.0 3.5e-155 516.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 ETS85242.1 - 4.7e-64 216.2 0.1 8.4e-64 215.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 ETS85242.1 - 1.4e-23 83.4 0.5 3.3e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 ETS85242.1 - 1.9e-08 34.1 0.1 5.9e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 ETS85242.1 - 0.00014 21.7 0.0 0.00056 19.7 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily Methyltransf_2 PF00891.13 ETS85244.1 - 3.9e-32 111.3 0.0 6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF1996 PF09362.5 ETS85245.1 - 1.3e-84 283.5 0.4 1.7e-84 283.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Scytalone_dh PF02982.9 ETS85246.1 - 2.6e-15 56.3 1.2 2.9e-15 56.2 0.8 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 ETS85246.1 - 4.5e-06 26.5 0.8 6.3e-06 26.1 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.14 ETS85247.1 - 1.3e-18 67.2 0.2 3.2e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS85247.1 - 0.00028 20.8 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS85247.1 - 0.0006 18.7 0.0 0.09 11.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.7 ETS85247.1 - 0.08 11.8 0.1 1.4 7.7 0.0 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein CVNH PF08881.5 ETS85248.1 - 0.00048 20.3 0.1 0.00075 19.6 0.1 1.4 1 1 0 1 1 1 1 CVNH domain adh_short PF00106.20 ETS85249.1 - 5.1e-29 101.3 0.8 7.4e-29 100.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85249.1 - 3.1e-16 59.5 0.3 4.3e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS85249.1 - 1.3e-10 41.4 0.2 1.7e-10 41.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS85249.1 - 8.9e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS85249.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS85249.1 - 0.0017 18.4 1.5 0.018 15.0 0.6 2.5 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS85249.1 - 0.0019 16.9 0.0 0.003 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 ETS85249.1 - 0.0026 16.8 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 ETS85249.1 - 0.0071 16.0 1.2 0.014 15.0 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 ETS85249.1 - 0.0077 16.0 1.2 0.017 14.9 0.8 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SBP_bac_11 PF13531.1 ETS85249.1 - 0.028 14.0 1.0 0.25 10.9 0.6 2.2 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein TRI12 PF06609.8 ETS85250.1 - 4e-29 101.2 21.7 5e-29 100.9 15.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 ETS85250.1 - 9.2e-21 73.9 56.7 1.1e-20 73.7 36.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85250.1 - 3.9e-10 38.8 11.5 3.9e-10 38.8 8.0 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Prefoldin PF02996.12 ETS85251.1 - 2.3e-35 120.8 0.3 9.1e-35 118.9 0.0 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 ETS85251.1 - 2.9e-05 23.7 0.5 0.002 17.8 0.0 2.8 2 1 0 2 2 2 1 Prefoldin subunit Filament PF00038.16 ETS85251.1 - 0.0016 17.9 1.4 0.16 11.4 0.1 2.1 2 0 0 2 2 2 2 Intermediate filament protein FlaC_arch PF05377.6 ETS85251.1 - 0.0024 17.7 1.1 3.2 7.7 0.0 2.9 3 0 0 3 3 3 2 Flagella accessory protein C (FlaC) End3 PF12761.2 ETS85251.1 - 0.0059 16.2 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 HR1 PF02185.11 ETS85251.1 - 0.0061 16.2 0.8 0.037 13.7 0.0 2.2 2 1 0 2 2 2 1 Hr1 repeat EzrA PF06160.7 ETS85251.1 - 0.026 12.7 0.8 0.34 9.0 0.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Laminin_II PF06009.7 ETS85251.1 - 0.047 13.4 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.6 ETS85251.1 - 0.066 13.6 1.4 8.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4201 PF13870.1 ETS85251.1 - 0.088 12.2 2.3 0.28 10.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) PspA_IM30 PF04012.7 ETS85251.1 - 0.1 11.9 2.9 5 6.4 0.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family CENP-F_leu_zip PF10473.4 ETS85251.1 - 0.41 10.5 4.9 6.1 6.7 0.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 ETS85251.1 - 0.97 9.3 5.7 5.5 6.9 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) V-SNARE PF05008.10 ETS85251.1 - 1.2 9.2 4.2 1.6 8.9 0.8 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.7 ETS85251.1 - 1.4 9.3 3.7 17 5.9 0.1 2.9 3 0 0 3 3 3 0 SlyX CRAL_TRIO PF00650.15 ETS85252.1 - 6.4e-36 123.2 0.0 1.1e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 ETS85252.1 - 8.5e-10 38.6 0.9 2.2e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain HTH_29 PF13551.1 ETS85252.1 - 0.0046 17.0 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix CRAL_TRIO_2 PF13716.1 ETS85252.1 - 0.014 15.2 0.0 0.065 13.1 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Mis14 PF08641.7 ETS85253.1 - 1.6e-06 28.1 1.9 1.3e-05 25.2 0.0 2.2 1 1 1 2 2 2 1 Kinetochore protein Mis14 like Hemerythrin PF01814.18 ETS85253.1 - 0.41 10.7 6.1 0.32 11.1 0.4 2.8 2 1 0 3 3 3 0 Hemerythrin HHE cation binding domain Glyco_hydro_7 PF00840.15 ETS85254.1 - 8.4e-189 627.4 17.9 9.5e-189 627.2 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CytadhesinP1 PF12378.3 ETS85254.1 - 0.06 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein DAO PF01266.19 ETS85255.1 - 7.5e-49 166.5 0.0 8.7e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85255.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS85255.1 - 0.016 15.0 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 ETS85255.1 - 0.1 12.7 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pantoate_transf PF02548.10 ETS85255.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Acetyltransf_1 PF00583.19 ETS85256.1 - 1.2e-11 44.4 0.1 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS85256.1 - 6.4e-09 35.9 0.2 7.9e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS85256.1 - 2.3e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS85256.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS85256.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS85256.1 - 0.003 17.3 0.1 0.0069 16.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS85256.1 - 0.015 15.0 0.2 0.038 13.7 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein DUF619 PF04768.8 ETS85256.1 - 0.02 14.2 0.0 0.25 10.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF619) GNAT_acetyltr_2 PF13718.1 ETS85256.1 - 0.027 13.8 0.1 0.038 13.3 0.0 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase 2 NmrA PF05368.8 ETS85257.1 - 5.8e-26 91.1 0.1 7.3e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 ETS85257.1 - 3.1e-10 39.6 0.0 4.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 ETS85257.1 - 3.8e-10 40.0 0.0 6.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS85257.1 - 0.00086 18.3 0.0 0.0033 16.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 ETS85257.1 - 0.00089 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 ETS85257.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 ETS85257.1 - 0.0089 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 ETS85257.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS85257.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.18 ETS85258.1 - 1e-09 37.6 0.0 1.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3085 PF11284.3 ETS85258.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) PALP PF00291.20 ETS85259.1 - 1.5e-56 191.8 1.6 1.8e-56 191.6 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 ETS85260.1 - 1.4e-26 93.1 64.2 3.8e-23 81.7 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS85260.1 - 6.8e-05 21.4 20.3 6.8e-05 21.4 14.0 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein HET PF06985.6 ETS85262.1 - 5.5e-34 117.3 1.7 9.1e-34 116.5 0.5 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4506 PF14958.1 ETS85262.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Planc_extracel PF07595.7 ETS85262.1 - 0.12 12.1 0.7 0.31 10.7 0.5 1.7 1 0 0 1 1 1 0 Planctomycete extracellular DUF2208 PF09973.4 ETS85263.1 - 0.04 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) p450 PF00067.17 ETS85264.1 - 4.6e-66 223.2 0.0 5.8e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS85265.1 - 7e-20 71.0 42.4 8.5e-13 47.7 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL73 PF03554.8 ETS85265.1 - 0.27 11.0 6.8 7 6.5 2.3 3.0 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF2583 PF10762.4 ETS85265.1 - 1.1 9.4 4.2 0.93 9.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DIOX_N PF14226.1 ETS85266.1 - 2.3e-29 102.2 0.1 3.7e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS85266.1 - 1.1e-24 86.5 0.0 1.8e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ring_hydroxyl_A PF00848.14 ETS85267.1 - 7.5e-36 123.7 1.8 4.6e-35 121.1 1.2 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS85267.1 - 1.2e-15 56.8 0.1 2.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_3 PF01494.14 ETS85268.1 - 2.3e-73 247.2 0.0 3e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 ETS85268.1 - 7.6e-30 103.7 0.0 1.7e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 ETS85268.1 - 6.5e-05 23.2 0.0 0.0037 17.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85268.1 - 0.0003 20.7 0.0 0.00095 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS85268.1 - 0.0009 17.8 0.0 0.0033 15.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS85268.1 - 0.0015 17.5 0.0 0.065 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS85268.1 - 0.0024 16.9 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 ETS85268.1 - 0.024 13.3 0.0 0.045 12.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 ETS85268.1 - 0.033 14.2 0.2 1.3 9.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85268.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS85268.1 - 0.063 12.1 0.1 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.1 ETS85268.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain SE PF08491.5 ETS85268.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Amidase PF01425.16 ETS85269.1 - 1.5e-99 333.8 0.0 1.8e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Amidase tRNA_anti-like PF12869.2 ETS85269.1 - 0.0049 16.3 0.2 0.008 15.6 0.2 1.3 1 0 0 1 1 1 1 tRNA_anti-like adh_short_C2 PF13561.1 ETS85270.1 - 3.3e-30 105.6 0.1 3.9e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS85270.1 - 1.3e-18 67.4 3.5 1.7e-18 67.1 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85270.1 - 1.4e-09 37.8 1.2 4.9e-09 36.1 0.8 1.9 1 1 0 1 1 1 1 KR domain Polysacc_deac_1 PF01522.16 ETS85271.1 - 3.6e-21 75.0 0.0 7.3e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 ETS85271.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Fungal_trans PF04082.13 ETS85272.1 - 8.2e-44 149.4 1.3 1.3e-43 148.8 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS85272.1 - 1.9e-05 24.6 13.4 0.00077 19.6 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS85272.1 - 4.3e-05 23.5 15.1 0.023 14.9 1.9 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger FAD_binding_3 PF01494.14 ETS85273.1 - 5.2e-21 75.0 0.1 6e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS85273.1 - 3e-10 39.5 4.3 2.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 ETS85273.1 - 3.6e-07 29.1 3.5 0.00025 19.8 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 ETS85273.1 - 2.8e-05 24.0 1.4 9.3e-05 22.3 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS85273.1 - 0.00034 19.6 0.7 0.00089 18.2 0.5 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS85273.1 - 0.0011 17.9 7.1 0.018 13.8 4.4 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS85273.1 - 0.0015 17.0 3.7 0.012 14.0 2.6 2.0 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 ETS85273.1 - 0.0037 16.4 0.9 0.62 9.1 0.4 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 ETS85273.1 - 0.0066 16.5 0.1 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS85273.1 - 0.0072 15.1 0.0 0.63 8.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 ETS85273.1 - 0.042 13.6 0.5 0.13 12.0 0.3 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS85273.1 - 0.065 13.1 2.4 0.1 12.4 1.7 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS85273.1 - 0.069 12.2 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 ETS85273.1 - 0.12 12.0 1.1 0.21 11.2 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 ETS85273.1 - 0.2 12.0 5.4 0.89 10.0 2.8 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS85273.1 - 0.22 10.5 2.5 7.1 5.5 1.2 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 ETS85273.1 - 2.8 6.7 8.8 2.2 7.0 4.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.15 ETS85274.1 - 3e-90 302.6 0.0 1.6e-89 300.3 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TPR_12 PF13424.1 ETS85275.1 - 1.6e-21 76.0 1.7 1.6e-14 53.5 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat HET PF06985.6 ETS85275.1 - 9e-20 71.2 8.8 2.7e-18 66.4 6.1 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 ETS85275.1 - 1.8e-15 56.2 6.4 0.00035 20.4 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 ETS85275.1 - 1.6e-10 40.3 0.0 6.6e-09 35.0 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain TPR_11 PF13414.1 ETS85275.1 - 3e-09 36.3 1.5 4.2e-06 26.3 0.0 3.2 2 1 2 4 4 4 2 TPR repeat TPR_1 PF00515.23 ETS85275.1 - 3.6e-07 29.5 1.1 0.2 11.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETS85275.1 - 2.2e-06 27.8 0.1 6.8e-05 23.0 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS85275.1 - 3.8e-06 27.0 0.0 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS85275.1 - 3.8e-06 26.7 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase TPR_2 PF07719.12 ETS85275.1 - 5.1e-06 25.9 1.3 3.8 7.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 ETS85275.1 - 0.00062 19.4 0.0 0.0078 15.8 0.0 2.5 3 0 0 3 3 3 1 NACHT domain TPR_8 PF13181.1 ETS85275.1 - 0.00089 18.8 0.2 7.3 6.6 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 ETS85275.1 - 0.0027 17.1 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein ArsA_ATPase PF02374.10 ETS85275.1 - 0.0031 16.5 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase TPR_17 PF13431.1 ETS85275.1 - 0.0084 16.2 1.3 2.1 8.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85275.1 - 0.011 15.5 0.8 5.4 7.0 0.1 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat AAA_17 PF13207.1 ETS85275.1 - 0.013 16.3 0.1 0.15 12.8 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_14 PF13173.1 ETS85275.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zot PF05707.7 ETS85275.1 - 0.036 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 ETS85275.1 - 0.073 13.2 0.0 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_31 PF13614.1 ETS85275.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETS85275.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 ETS85275.1 - 0.15 11.6 0.0 0.86 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS85275.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 ETS85275.1 - 0.17 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS85275.1 - 0.17 11.6 0.0 0.49 10.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TPR_16 PF13432.1 ETS85275.1 - 0.39 11.4 11.3 0.17 12.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS85275.1 - 1.5 9.4 5.2 61 4.4 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Flavin_Reduct PF01613.13 ETS85276.1 - 4.9e-15 55.6 0.0 6.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 ETS85276.1 - 2.9e-06 26.9 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Ada_Zn_binding PF02805.11 ETS85277.1 - 1.5e-30 104.5 5.3 1.5e-30 104.5 3.7 1.6 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_AraC PF00165.18 ETS85277.1 - 0.00012 21.7 0.1 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 ETS85277.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Lactamase_B PF00753.22 ETS85278.1 - 4.1e-15 55.9 4.9 1.2e-14 54.3 3.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS85278.1 - 3.2e-05 23.5 0.9 4.3e-05 23.1 0.6 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CFEM PF05730.6 ETS85280.1 - 3.5e-08 33.1 6.7 3.5e-08 33.1 4.6 1.8 2 0 0 2 2 2 1 CFEM domain Abhydrolase_5 PF12695.2 ETS85281.1 - 2.3e-15 56.6 0.3 3.3e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS85281.1 - 1.6e-07 31.4 3.4 1.1e-06 28.7 2.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 ETS85281.1 - 1.6e-05 23.8 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.8 ETS85281.1 - 6.1e-05 21.4 0.1 0.0079 14.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 ETS85281.1 - 6.3e-05 22.2 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 ETS85281.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 ETS85281.1 - 0.0017 17.3 0.5 0.023 13.5 0.1 2.5 2 1 0 2 2 2 1 Chlorophyllase enzyme PGAP1 PF07819.8 ETS85281.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 ETS85281.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF676 PF05057.9 ETS85281.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Y_phosphatase PF00102.22 ETS85283.1 - 2e-54 184.3 0.1 4e-54 183.4 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 ETS85283.1 - 0.0021 17.6 0.0 0.0067 16.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 ETS85283.1 - 0.0027 17.7 0.0 0.012 15.7 0.0 2.2 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 ETS85283.1 - 0.009 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family MUG2_C PF08593.5 ETS85283.1 - 0.27 11.4 3.2 9.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal DUF427 PF04248.7 ETS85284.1 - 2.5e-32 110.3 0.1 6.4e-24 83.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Folliculin PF11704.3 ETS85285.1 - 3.5e-28 98.2 0.0 2.2e-21 76.1 0.0 2.9 2 1 0 2 2 2 2 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.24 ETS85286.1 - 1.8e-45 154.3 0.2 6.6e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS85286.1 - 3.2e-09 36.6 0.3 1.2e-08 34.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS85286.1 - 4.2e-08 33.2 0.0 9.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETS85286.1 - 5e-07 29.8 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS85286.1 - 7.5e-07 29.3 0.7 0.001 19.2 0.0 2.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 ETS85286.1 - 3e-06 26.3 0.0 5.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETS85286.1 - 0.00012 21.9 0.2 0.00059 19.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 ETS85286.1 - 0.00034 19.7 0.0 0.00081 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 ETS85286.1 - 0.00036 20.2 0.1 0.056 13.0 0.0 3.2 4 0 0 4 4 4 1 NACHT domain AAA_17 PF13207.1 ETS85286.1 - 0.00038 21.2 0.0 0.0019 19.0 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_28 PF13521.1 ETS85286.1 - 0.00042 20.3 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS85286.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 ETS85286.1 - 0.0014 17.7 0.1 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 ETS85286.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 ETS85286.1 - 0.0016 17.2 0.0 0.0029 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 ETS85286.1 - 0.0027 17.4 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 ETS85286.1 - 0.0036 16.9 0.0 0.011 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS85286.1 - 0.0044 16.6 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 ETS85286.1 - 0.0054 17.0 0.8 0.81 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 ETS85286.1 - 0.0055 16.3 0.9 0.017 14.7 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 ETS85286.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETS85286.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 ETS85286.1 - 0.0083 15.8 1.1 0.06 13.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 ETS85286.1 - 0.0089 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 ETS85286.1 - 0.011 15.2 0.4 0.024 14.0 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 ETS85286.1 - 0.011 15.2 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 ETS85286.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 ETS85286.1 - 0.02 14.2 2.9 0.075 12.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain KaiC PF06745.8 ETS85286.1 - 0.03 13.4 1.0 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 ETS85286.1 - 0.03 14.6 0.0 0.099 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 ETS85286.1 - 0.045 13.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 ETS85286.1 - 0.066 13.2 0.1 0.31 11.0 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 ETS85286.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 ETS85286.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mpv17_PMP22 PF04117.7 ETS85288.1 - 4.6e-15 54.9 9.6 8.9e-15 54.0 6.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pyr_redox_3 PF13738.1 ETS85289.1 - 9.5e-21 74.7 0.0 1.9e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS85289.1 - 2.5e-07 29.9 0.3 0.0014 17.6 0.0 2.8 3 1 1 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS85289.1 - 2.4e-05 24.1 0.0 0.0039 16.9 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS85289.1 - 0.00035 20.5 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S10 PF00450.17 ETS85290.1 - 4.7e-78 263.2 0.0 6.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase COX14 PF14880.1 ETS85290.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF1295 PF06966.7 ETS85292.1 - 4.2e-17 62.2 0.0 5.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 ETS85292.1 - 1.9e-06 26.6 4.0 7.4e-06 24.7 2.8 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 ETS85292.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 ETS85292.1 - 0.018 15.1 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Rio2_N PF09202.6 ETS85292.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal peroxidase PF00141.18 ETS85293.1 - 1.8e-23 83.2 0.0 2.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.11 ETS85295.1 - 6.5e-41 140.2 44.9 6.5e-41 140.2 31.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS85295.1 - 4.9e-10 38.2 16.7 1.1e-09 37.0 11.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS85295.1 - 6.4e-07 28.2 34.3 2.2e-06 26.5 11.0 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Mannitol_dh_C PF08125.8 ETS85297.1 - 8.6e-77 257.6 0.0 1.2e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 ETS85297.1 - 6.1e-49 165.8 0.0 1.2e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain p450 PF00067.17 ETS85298.1 - 1.4e-17 63.3 0.0 2.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.1 ETS85301.1 - 3.6e-11 43.1 0.2 1.2e-07 31.8 0.0 3.9 2 2 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 ETS85301.1 - 5.3e-05 23.5 1.9 0.74 10.3 0.1 4.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 ETS85301.1 - 0.00035 20.3 1.8 0.22 11.6 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.18 ETS85301.1 - 0.012 15.4 2.0 0.49 10.3 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.20 ETS85302.1 - 9.9e-32 109.4 0.0 1.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2048 PF09752.4 ETS85302.1 - 0.00043 19.2 0.6 0.00067 18.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 ETS85302.1 - 0.0024 17.6 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS85302.1 - 0.0026 17.6 0.0 0.0036 17.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 ETS85302.1 - 0.0033 16.8 3.0 0.042 13.1 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.15 ETS85302.1 - 0.0035 16.7 0.3 0.038 13.4 0.3 2.1 2 1 0 2 2 2 1 Putative esterase Thioesterase PF00975.15 ETS85302.1 - 0.014 15.5 0.6 0.039 14.1 0.5 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 ETS85302.1 - 0.047 13.2 0.5 0.083 12.4 0.3 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 ETS85303.1 - 1.2e-06 27.9 0.2 4.7e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85303.1 - 0.00019 20.4 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS85303.1 - 0.0013 17.7 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 ETS85304.1 - 8.8e-20 71.0 1.7 8.8e-19 67.7 1.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85304.1 - 1.8e-09 36.9 1.0 6.6e-08 31.8 0.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85304.1 - 2.4e-07 30.6 0.5 7.4e-07 29.1 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS85304.1 - 1.4e-06 28.3 0.4 2.4e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS85304.1 - 3.6e-06 26.1 1.8 6.9e-06 25.1 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS85304.1 - 0.00023 21.5 0.4 0.0011 19.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS85304.1 - 0.00026 19.7 0.2 0.017 13.7 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 ETS85304.1 - 0.00062 18.3 1.1 0.011 14.2 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.11 ETS85304.1 - 0.00072 19.0 0.1 0.012 15.0 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 ETS85304.1 - 0.001 18.2 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 ETS85304.1 - 0.0019 17.1 0.1 0.0025 16.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS85304.1 - 0.0033 16.5 0.5 0.0057 15.7 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS85304.1 - 0.0043 16.1 0.3 0.007 15.4 0.2 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 ETS85304.1 - 0.017 14.8 0.1 0.6 9.8 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_18 PF12847.2 ETS85304.1 - 0.025 15.1 0.1 0.1 13.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 ETS85304.1 - 0.027 14.5 0.2 0.047 13.7 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.9 ETS85304.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain 3HCDH_N PF02737.13 ETS85304.1 - 0.081 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS85304.1 - 0.094 12.2 0.2 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 ETS85304.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 ETS85304.1 - 0.18 10.6 0.3 0.71 8.7 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.17 ETS85305.1 - 2e-66 224.4 0.0 2.6e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 ETS85306.1 - 7.7e-34 117.5 0.5 1.6e-33 116.4 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85306.1 - 1.4e-17 64.0 0.0 7.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS85306.1 - 1.1e-13 51.1 0.3 1.4e-12 47.5 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS85306.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase MFS_1 PF07690.11 ETS85307.1 - 3.4e-29 101.6 33.2 3.4e-29 101.6 23.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 ETS85309.1 - 3.7e-19 69.0 0.0 7.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS85309.1 - 7.6e-13 49.0 0.0 3.6e-12 46.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS85309.1 - 5.7e-09 35.7 0.0 1.1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85309.1 - 4.7e-07 30.2 0.0 9.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS85309.1 - 1.2e-05 25.5 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS85309.1 - 8e-05 23.0 0.0 0.0004 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS85309.1 - 0.002 17.7 0.0 0.0052 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 ETS85309.1 - 0.0079 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 ETS85309.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 ETS85309.1 - 0.021 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 ETS85309.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_3 PF01494.14 ETS85310.1 - 1.1e-11 44.4 0.0 3.9e-06 26.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 ETS85310.1 - 0.00065 19.6 0.1 0.0017 18.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS85310.1 - 0.0035 16.2 0.1 0.017 14.0 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS85310.1 - 0.0044 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Esterase PF00756.15 ETS85311.1 - 5.4e-12 45.6 0.0 3.8e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 ETS85311.1 - 0.0015 17.8 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS85311.1 - 0.018 14.9 0.0 0.047 13.5 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 ETS85312.1 - 4.6e-14 51.8 32.9 8.1e-14 51.0 19.3 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 ETS85312.1 - 0.0042 15.1 5.9 0.24 9.3 0.5 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Lactamase_B_3 PF13483.1 ETS85313.1 - 5.9e-08 32.5 0.0 5.9e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS85313.1 - 2.9e-06 27.0 0.5 4.6e-06 26.4 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS85313.1 - 0.00015 21.3 0.1 0.00026 20.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 ETS85314.1 - 9.3e-09 34.5 3.5 1.7e-08 33.7 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 ETS85315.1 - 3.4e-162 539.5 0.9 5.5e-162 538.8 0.6 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 ETS85315.1 - 1.1e-16 60.4 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 ETS85315.1 - 3.8e-09 36.1 0.0 6.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_3 PF00933.16 ETS85316.1 - 1.5e-53 181.7 0.0 2.2e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS85316.1 - 5.1e-41 140.6 0.0 1.4e-40 139.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS85316.1 - 1.2e-24 85.9 0.2 2.2e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Pectate_lyase_3 PF12708.2 ETS85317.1 - 4.7e-80 268.9 24.9 1.1e-64 218.6 5.6 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 ETS85317.1 - 2.6e-07 29.9 2.4 0.0014 18.0 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF3129 PF11327.3 ETS85318.1 - 7.5e-69 231.2 19.0 5.2e-67 225.2 13.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) UDPGT PF00201.13 ETS85319.1 - 1.2e-11 43.8 0.1 1.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 ETS85319.1 - 0.00041 20.1 0.0 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 ETS85319.1 - 0.2 11.2 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF1358 PF07096.6 ETS85320.1 - 0.069 12.8 1.1 0.66 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) CCDC92 PF14916.1 ETS85321.1 - 0.0034 16.9 0.1 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain of unknown function MFS_1 PF07690.11 ETS85322.1 - 4.6e-24 84.7 44.1 5.6e-24 84.5 30.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 ETS85323.1 - 3.5e-11 42.9 0.0 5.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 ETS85323.1 - 3.8e-06 26.5 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 ETS85323.1 - 8.6e-05 22.7 0.0 0.00013 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS85323.1 - 0.00051 19.9 0.0 0.00098 19.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS85323.1 - 0.0013 18.8 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS85323.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 ETS85323.1 - 0.012 15.5 0.0 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS85323.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 ETS85325.1 - 3.3e-20 72.6 0.0 5.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 ETS85327.1 - 3.8e-53 175.5 15.1 1e-08 34.7 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 ETS85327.1 - 4.1e-11 42.4 1.3 4.1e-11 42.4 0.9 2.3 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 ETS85327.1 - 7.1e-08 31.0 9.9 0.032 12.3 0.1 5.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 ETS85327.1 - 1.5e-07 30.8 1.6 1.5e-07 30.8 1.1 2.2 2 0 0 2 2 2 1 F-box domain Acetyltransf_1 PF00583.19 ETS85328.1 - 3.6e-11 42.9 0.0 6.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS85328.1 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS85328.1 - 0.0059 16.7 0.0 0.0092 16.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS85328.1 - 0.006 16.4 0.1 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Mito_carr PF00153.22 ETS85329.1 - 1.6e-70 232.8 2.8 4.5e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 ETS85330.1 - 1.8e-23 82.7 0.0 4.4e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Tannase PF07519.6 ETS85331.1 - 1.2e-96 324.3 0.2 1.3e-95 320.8 0.1 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Cyclase PF04199.8 ETS85332.1 - 1.4e-14 54.1 0.9 2.1e-14 53.6 0.6 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.1 ETS85333.1 - 1.4e-26 93.8 0.0 8.3e-25 88.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85333.1 - 8.8e-08 30.7 0.0 1.9e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS85333.1 - 1.1e-05 24.5 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS85333.1 - 1.9e-05 24.5 0.1 7.5e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 ETS85333.1 - 0.00087 18.4 0.0 0.0023 17.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 ETS85333.1 - 0.0011 18.7 0.6 0.45 10.2 0.1 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS85333.1 - 0.0026 17.6 2.6 3.6 7.4 0.1 3.6 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS85333.1 - 0.0027 17.8 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS85333.1 - 0.079 13.2 0.3 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding OmdA PF13376.1 ETS85334.1 - 6.8e-11 41.6 0.1 1.7e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated HTH_23 PF13384.1 ETS85334.1 - 0.0036 16.9 0.1 0.0099 15.5 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Trp_repressor PF01371.14 ETS85334.1 - 0.07 13.0 0.4 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 Trp repressor protein HTH_38 PF13936.1 ETS85334.1 - 0.076 12.5 0.5 0.18 11.4 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cu_amine_oxid PF01179.15 ETS85335.1 - 3.6e-163 543.0 0.0 4.4e-163 542.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 ETS85335.1 - 6.5e-11 42.1 0.0 2.3e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 ETS85335.1 - 5.2e-08 32.8 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain MFS_1 PF07690.11 ETS85338.1 - 1.1e-22 80.3 20.3 1.4e-22 79.9 14.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 ETS85339.1 - 7.6e-46 156.8 0.0 9.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 ETS85340.1 - 1.2e-16 60.7 0.6 1.2e-15 57.4 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85340.1 - 2.8e-06 26.5 3.2 0.00013 21.0 1.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85340.1 - 8.4e-06 25.7 1.4 8.4e-06 25.7 1.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS85340.1 - 0.00016 20.6 2.3 0.0003 19.7 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS85340.1 - 0.00071 19.5 0.6 0.0013 18.6 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS85340.1 - 0.003 16.4 1.3 0.0048 15.8 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 ETS85340.1 - 0.0039 15.7 0.8 0.0072 14.8 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 ETS85340.1 - 0.0064 16.8 0.9 0.014 15.7 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 ETS85340.1 - 0.0096 15.5 0.3 0.018 14.5 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 ETS85340.1 - 0.044 13.8 0.1 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS85340.1 - 0.046 12.8 2.8 0.075 12.0 1.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 ETS85340.1 - 0.064 12.7 0.2 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 ETS85340.1 - 0.074 11.6 0.2 0.41 9.2 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Rossmann-like PF10727.4 ETS85340.1 - 0.075 12.7 0.6 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 Rossmann-like domain Amino_oxidase PF01593.19 ETS85340.1 - 0.085 11.9 0.3 0.24 10.4 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 ETS85340.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DBR1 PF05011.8 ETS85341.1 - 3.3e-44 150.2 0.0 4.9e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 ETS85341.1 - 3.8e-10 39.4 0.9 6.4e-10 38.7 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.6 ETS85341.1 - 0.36 11.3 19.3 0.66 10.4 13.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family TPR_12 PF13424.1 ETS85342.1 - 3.2e-93 305.7 28.8 2.7e-18 65.6 0.2 7.0 3 1 6 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 ETS85342.1 - 2.3e-75 246.6 22.5 2.2e-13 49.6 0.5 9.4 10 0 0 10 10 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 ETS85342.1 - 9.8e-19 66.7 2.8 1.8e-06 27.5 0.1 5.7 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 ETS85342.1 - 6.7e-14 50.6 7.1 0.071 13.0 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85342.1 - 2.1e-12 46.0 2.3 0.0065 16.0 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85342.1 - 3.9e-12 46.4 10.1 0.00034 21.1 0.8 5.4 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85342.1 - 1.8e-11 42.9 11.9 0.052 13.3 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS85342.1 - 1.6e-09 37.7 0.6 0.0078 16.3 0.5 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 ETS85342.1 - 2.3e-09 36.7 13.5 0.027 14.8 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS85342.1 - 8.7e-08 31.7 1.8 0.43 10.9 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 ETS85342.1 - 1.3e-07 30.8 0.0 2.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 ETS85342.1 - 1.7e-07 31.4 10.1 0.016 15.5 0.3 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85342.1 - 1.7e-05 24.9 18.2 0.31 11.8 0.5 7.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 ETS85342.1 - 2.6e-05 24.2 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85342.1 - 0.00051 19.8 0.0 0.0018 18.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS85342.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF3089 PF11288.3 ETS85342.1 - 0.074 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PPR PF01535.15 ETS85342.1 - 0.093 12.7 0.1 94 3.3 0.0 4.0 4 0 0 4 4 3 0 PPR repeat SHNi-TPR PF10516.4 ETS85342.1 - 0.11 11.6 0.1 19 4.5 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR DUF4404 PF14357.1 ETS85342.1 - 0.46 10.9 8.2 20 5.7 0.0 5.2 3 2 3 6 6 6 0 Domain of unknown function (DUF4404) TPR_8 PF13181.1 ETS85342.1 - 0.94 9.4 0.0 0.94 9.4 0.0 5.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS85342.1 - 4.8 7.8 13.1 47 4.7 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HET PF06985.6 ETS85344.1 - 1.2e-35 122.6 0.2 3.1e-35 121.3 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 ETS85345.1 - 7.8e-10 38.3 2.1 1.2e-09 37.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS85345.1 - 5.6e-08 32.2 2.1 6.7e-08 31.9 0.3 2.0 2 0 0 2 2 2 1 F-box domain Apc5 PF12862.2 ETS85345.1 - 0.047 13.5 0.1 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Skp1_POZ PF03931.10 ETS85346.1 - 1.6e-12 47.2 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.17 ETS85347.1 - 1.1e-47 161.4 0.0 1.4e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS85347.1 - 5e-12 46.3 0.0 9.8e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS85347.1 - 1e-05 24.8 0.0 2.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Asp PF00026.18 ETS85348.1 - 1.6e-65 221.4 18.1 1.4e-45 155.9 9.9 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS85348.1 - 4.9e-07 29.8 0.8 4.9e-07 29.8 0.5 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Sugar_tr PF00083.19 ETS85349.1 - 3.1e-92 309.5 25.5 3.6e-92 309.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85349.1 - 7.9e-11 41.2 42.2 2.7e-09 36.2 28.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Flavi_NS4A PF01350.12 ETS85349.1 - 0.29 10.6 4.1 0.26 10.8 0.3 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ras PF00071.17 ETS85350.1 - 4.3e-13 48.9 0.0 5.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.1 ETS85351.1 - 0.098 12.1 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.13 ETS85352.1 - 4.6e-06 25.6 0.0 6.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS85353.1 - 0.003 16.4 0.1 0.0041 16.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 ETS85354.1 - 2.4e-18 66.1 0.0 4.7e-11 42.1 0.0 3.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS85354.1 - 0.0013 17.7 0.1 1.2 7.9 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS85354.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS85354.1 - 0.04 12.8 0.1 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 ETS85354.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 ETS85355.1 - 1.6e-26 92.8 24.8 1.6e-26 92.8 17.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.1 ETS85355.1 - 0.0038 16.6 0.1 0.0038 16.6 0.1 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4131) FtsH_ext PF06480.10 ETS85355.1 - 0.039 14.1 0.2 0.87 9.7 0.0 2.7 2 0 0 2 2 2 0 FtsH Extracellular OATP PF03137.15 ETS85355.1 - 6.5 4.6 11.6 0.4 8.6 0.4 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 ETS85357.1 - 1e-45 156.1 0.0 1.3e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2787 PF10980.3 ETS85357.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) NACHT PF05729.7 ETS85358.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Phostensin_N PF13916.1 ETS85358.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Glyco_hydro_18 PF00704.23 ETS85359.1 - 6.1e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos PF00149.23 ETS85361.1 - 5.4e-38 130.4 0.1 9.7e-33 113.2 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 ETS85361.1 - 0.029 14.1 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Smg4_UPF3 PF03467.10 ETS85362.1 - 1.6e-20 73.7 0.1 1.6e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 ETS85362.1 - 3.3e-07 30.1 0.0 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS85362.1 - 7.2e-07 28.7 0.2 6.4e-05 22.5 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS85362.1 - 0.00067 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PA14_2 PF10528.4 ETS85363.1 - 2.1e-16 59.8 1.8 3.2e-16 59.2 1.2 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 ETS85363.1 - 0.0032 17.1 1.3 0.005 16.4 0.1 1.8 2 0 0 2 2 2 1 PA14 domain Glyco_hydro_3 PF00933.16 ETS85364.1 - 1.8e-48 165.0 0.0 2.6e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS85364.1 - 5.8e-42 143.7 0.0 1.1e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS85364.1 - 1.4e-23 82.6 0.1 2.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.17 ETS85365.1 - 2.3e-42 145.1 0.0 1.1e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Nramp PF01566.13 ETS85365.1 - 0.15 10.7 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein MFS_1 PF07690.11 ETS85366.1 - 5.4e-34 117.4 25.8 7.1e-33 113.7 19.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF456 PF04306.8 ETS85366.1 - 4.4 7.3 14.4 0.32 11.0 3.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF456) DAO PF01266.19 ETS85367.1 - 1.3e-49 168.9 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85367.1 - 5.9e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS85367.1 - 2.7e-05 24.3 0.0 0.0014 18.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS85367.1 - 0.00018 21.3 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 ETS85367.1 - 0.00027 20.1 0.0 0.00084 18.5 0.0 1.8 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 ETS85367.1 - 0.0017 17.3 0.0 0.037 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 ETS85367.1 - 0.048 12.5 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HAD_2 PF13419.1 ETS85368.1 - 4e-28 98.8 0.0 5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS85368.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Epimerase PF01370.16 ETS85369.1 - 2.6e-22 79.4 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS85369.1 - 8.6e-13 47.6 0.0 1.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS85369.1 - 3.8e-10 39.1 0.0 3.6e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 ETS85369.1 - 5.2e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 ETS85369.1 - 5.1e-07 29.7 0.0 8.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85369.1 - 2.1e-06 27.5 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS85369.1 - 0.0001 21.3 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 ETS85369.1 - 0.0013 18.0 0.1 0.0056 15.9 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family Glyco_hydr_30_2 PF14587.1 ETS85370.1 - 6.3e-13 48.4 2.7 4.3e-12 45.6 0.3 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 ETS85370.1 - 2.3e-10 39.2 0.9 7.8e-08 30.9 0.2 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 DUF4596 PF15363.1 ETS85370.1 - 3.6 7.5 7.2 8 6.4 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) F-box-like PF12937.2 ETS85372.1 - 1.6e-08 34.0 0.3 4.2e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS85372.1 - 0.15 11.7 0.4 1.9 8.2 0.1 2.8 2 1 0 2 2 2 0 F-box domain TRF PF08558.5 ETS85376.1 - 5.9e-49 166.5 0.3 1.2e-48 165.5 0.2 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 ETS85376.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 ETS85376.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain AAA_11 PF13086.1 ETS85377.1 - 5.1e-10 39.3 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS85377.1 - 0.0053 16.3 0.0 0.43 10.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 ETS85377.1 - 0.042 13.3 0.0 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Aldedh PF00171.17 ETS85378.1 - 2.6e-188 626.0 0.3 2.9e-188 625.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS85378.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) COesterase PF00135.23 ETS85379.1 - 6.5e-101 338.6 0.0 7.8e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS85379.1 - 2.9e-07 30.3 0.1 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS85379.1 - 0.055 12.6 0.2 0.099 11.8 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA_12 PF13087.1 ETS85380.1 - 4.7e-16 58.7 0.0 8.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS85380.1 - 1.7e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS85380.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Herpes_Helicase PF02689.9 ETS85380.1 - 0.38 8.4 0.0 0.58 7.8 0.0 1.1 1 0 0 1 1 1 0 Helicase CCDC155 PF14662.1 ETS85381.1 - 2e-07 30.8 14.7 3.6e-07 29.9 10.2 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 HALZ PF02183.13 ETS85381.1 - 1.4e-05 24.6 16.6 6.6e-05 22.5 0.7 4.4 5 0 0 5 5 4 2 Homeobox associated leucine zipper ADIP PF11559.3 ETS85381.1 - 8.8e-05 22.4 18.4 0.023 14.6 4.3 2.3 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Lebercilin PF15619.1 ETS85381.1 - 0.0012 18.3 16.8 0.0016 17.8 11.7 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 ETS85381.1 - 0.002 17.6 7.1 0.002 17.6 4.9 2.3 1 1 1 2 2 2 1 Intermediate filament protein Bap31 PF05529.7 ETS85381.1 - 0.0027 17.2 8.5 0.085 12.3 2.7 2.4 1 1 1 2 2 2 1 B-cell receptor-associated protein 31-like DivIVA PF05103.8 ETS85381.1 - 0.011 15.7 16.1 0.025 14.6 1.7 2.7 1 1 2 3 3 3 0 DivIVA protein DUF2968 PF11180.3 ETS85381.1 - 0.012 15.0 3.3 0.012 15.0 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Sec2p PF06428.6 ETS85381.1 - 0.014 15.2 3.5 0.014 15.2 2.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF972 PF06156.8 ETS85381.1 - 0.018 15.3 14.7 0.32 11.3 2.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 ETS85381.1 - 0.026 14.6 8.1 0.43 10.6 1.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2353 PF09789.4 ETS85381.1 - 0.028 13.6 12.8 0.037 13.2 5.3 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF904 PF06005.7 ETS85381.1 - 0.032 14.5 20.5 0.18 12.1 4.6 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Spc7 PF08317.6 ETS85381.1 - 0.033 12.8 15.9 0.012 14.3 5.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.3 ETS85381.1 - 0.033 11.5 15.8 0.13 9.5 10.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Ets PF00178.17 ETS85381.1 - 0.034 14.2 2.3 0.034 14.2 1.6 1.7 2 0 0 2 2 1 0 Ets-domain DUF4600 PF15372.1 ETS85381.1 - 0.04 14.1 2.7 0.04 14.1 1.9 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4600) Bacillus_HBL PF05791.6 ETS85381.1 - 0.041 13.2 6.4 0.4 10.0 1.0 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Rab5-bind PF09311.6 ETS85381.1 - 0.043 13.7 11.1 0.06 13.2 7.7 1.3 1 0 0 1 1 1 0 Rabaptin-like protein APG6 PF04111.7 ETS85381.1 - 0.049 12.6 19.6 0.15 11.1 3.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TLE_N PF03920.10 ETS85381.1 - 0.054 13.3 0.3 0.054 13.3 0.2 1.9 2 1 0 2 2 1 0 Groucho/TLE N-terminal Q-rich domain Med9 PF07544.8 ETS85381.1 - 0.056 13.1 9.2 1.2 8.9 0.0 3.8 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 ETS85381.1 - 0.066 13.0 16.3 2.8 7.8 3.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 ETS85381.1 - 0.082 11.9 18.1 0.11 11.5 12.5 1.1 1 0 0 1 1 1 0 Tropomyosin TBPIP PF07106.8 ETS85381.1 - 0.13 11.8 14.1 0.54 9.7 1.8 2.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snapin_Pallidin PF14712.1 ETS85381.1 - 0.13 12.5 10.3 0.82 10.0 1.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Mod_r PF07200.8 ETS85381.1 - 0.15 11.9 13.0 0.88 9.4 0.7 2.6 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 ETS85381.1 - 0.18 11.8 18.3 1.8 8.5 0.0 4.1 2 1 2 4 4 4 0 bZIP transcription factor IncA PF04156.9 ETS85381.1 - 0.36 10.4 15.3 0.49 9.9 8.5 2.3 1 1 1 2 2 2 0 IncA protein DUF148 PF02520.12 ETS85381.1 - 0.38 10.5 7.9 3 7.6 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF148 MscS_porin PF12795.2 ETS85381.1 - 0.49 9.6 10.4 0.41 9.9 1.4 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain BRE1 PF08647.6 ETS85381.1 - 0.67 9.9 11.7 1.4 8.9 2.9 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.2 ETS85381.1 - 0.69 9.7 19.4 4.6 7.0 0.3 2.4 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.1 ETS85381.1 - 0.74 8.9 18.3 2.1 7.4 4.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 ETS85381.1 - 0.98 8.2 19.4 2.3 7.0 9.2 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Microtub_assoc PF07989.6 ETS85381.1 - 1.3 8.9 9.0 0.28 11.0 0.9 3.1 2 1 1 3 3 3 0 Microtubule associated DUF3450 PF11932.3 ETS85381.1 - 1.6 7.8 12.2 39 3.3 7.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3186 PF11382.3 ETS85381.1 - 1.9 7.5 9.7 5.1 6.1 1.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3186) CALCOCO1 PF07888.6 ETS85381.1 - 1.9 6.6 14.4 1.4 7.1 8.2 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 ETS85381.1 - 2.3 6.5 12.0 0.77 8.0 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SlyX PF04102.7 ETS85381.1 - 2.5 8.5 9.8 5.8 7.3 0.2 3.3 1 1 1 3 3 3 0 SlyX CAF-1_p150 PF11600.3 ETS85381.1 - 2.8 7.2 12.2 3.5 6.9 8.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rootletin PF15035.1 ETS85381.1 - 2.9 7.8 20.4 2.2 8.2 1.7 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion UPF0449 PF15136.1 ETS85381.1 - 2.9 8.1 7.7 7 6.9 0.7 3.2 2 2 1 3 3 3 0 Uncharacterised protein family UPF0449 Troponin PF00992.15 ETS85381.1 - 2.9 7.9 15.8 0.5 10.4 6.1 2.3 1 1 1 2 2 2 0 Troponin Orbi_VP5 PF00901.12 ETS85381.1 - 4.7 5.2 9.8 0.47 8.6 2.8 1.8 1 1 0 2 2 2 0 Orbivirus outer capsid protein VP5 Seryl_tRNA_N PF02403.17 ETS85381.1 - 6.1 6.9 14.9 47 4.0 4.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_Mu_Gam PF07352.7 ETS85381.1 - 6.4 6.2 10.4 19 4.7 4.8 2.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein bZIP_Maf PF03131.12 ETS85381.1 - 6.4 7.1 16.5 0.087 13.1 1.1 3.4 2 1 0 3 3 3 0 bZIP Maf transcription factor DASH_Spc34 PF08657.5 ETS85381.1 - 6.6 6.3 12.5 98 2.4 8.3 2.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF2681 PF10883.3 ETS85381.1 - 6.8 6.9 11.0 4.7 7.4 0.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2681) Cep57_CLD_2 PF14197.1 ETS85381.1 - 7.8 6.5 19.1 7.6 6.5 4.2 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 ETS85381.1 - 7.8 6.0 20.3 1.5 8.3 1.6 4.1 1 1 3 4 4 4 0 Septum formation initiator FliD_C PF07195.7 ETS85381.1 - 8 5.6 8.3 51 3.0 3.5 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMF_DNA_bd PF12329.3 ETS85381.1 - 8.1 6.3 18.5 2 8.2 0.3 3.6 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 ETS85381.1 - 8.9 6.3 14.4 4.2 7.3 0.0 3.9 2 1 3 5 5 4 0 TSC-22/dip/bun family IncA PF04156.9 ETS85382.1 - 8.7e-06 25.4 0.7 1.1e-05 25.1 0.5 1.1 1 0 0 1 1 1 1 IncA protein DUF4201 PF13870.1 ETS85382.1 - 0.00041 19.8 3.1 0.00041 19.8 2.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 ETS85382.1 - 0.00054 19.6 1.1 0.001 18.7 0.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.4 ETS85382.1 - 0.00087 18.6 4.9 0.0033 16.7 3.4 1.7 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.6 ETS85382.1 - 0.001 18.9 2.5 0.001 18.9 0.5 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.1 ETS85382.1 - 0.051 12.7 1.4 0.095 11.8 1.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 ETS85382.1 - 0.052 13.0 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pilin_PilA PF14245.1 ETS85382.1 - 0.093 13.2 0.2 26 5.3 0.0 2.6 3 0 0 3 3 3 0 Type IV pilin PilA Pox_A_type_inc PF04508.7 ETS85382.1 - 0.1 12.4 2.6 0.61 10.0 0.0 3.5 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat APG6 PF04111.7 ETS85382.1 - 0.11 11.5 1.4 0.16 11.0 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 ETS85382.1 - 0.13 11.4 0.8 0.23 10.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.8 ETS85382.1 - 0.2 10.6 0.5 0.29 10.1 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.10 ETS85382.1 - 0.21 10.7 1.6 0.28 10.3 1.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3166 PF11365.3 ETS85382.1 - 0.31 11.5 3.6 0.95 9.9 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Atg14 PF10186.4 ETS85382.1 - 0.89 8.4 5.9 2.3 7.0 1.3 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 ETS85382.1 - 1.5 8.4 4.5 0.54 9.8 1.3 1.5 2 0 0 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 ETS85382.1 - 1.5 8.5 6.6 1.9 8.2 3.0 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 ETS85382.1 - 2.8 7.5 5.7 1.4 8.4 0.4 2.5 2 1 1 3 3 3 0 Septum formation initiator DUF904 PF06005.7 ETS85382.1 - 3.2 8.1 8.8 13 6.1 6.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) MIP PF00230.15 ETS85383.1 - 1.1e-43 149.3 16.4 1.3e-43 149.1 11.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pec_lyase_C PF00544.14 ETS85384.1 - 1.1e-19 70.7 1.0 1.8e-19 69.9 0.7 1.4 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 ETS85384.1 - 3.7e-12 45.6 14.4 1.3e-11 43.9 10.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain CDC27 PF09507.5 ETS85384.1 - 0.51 9.5 6.3 0.68 9.0 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1049 PF06305.6 ETS85385.1 - 0.18 11.3 1.6 0.33 10.4 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) IncA PF04156.9 ETS85385.1 - 0.62 9.6 5.9 0.96 9.0 4.1 1.3 1 0 0 1 1 1 0 IncA protein AA_permease PF00324.16 ETS85386.1 - 5.5e-129 430.6 44.9 6.2e-129 430.4 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS85386.1 - 2e-36 125.4 51.3 2.4e-36 125.1 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease Arch_ATPase PF01637.13 ETS85387.1 - 6.7e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 ETS85387.1 - 5e-06 26.6 2.5 0.0001 22.3 0.7 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 ETS85387.1 - 0.0029 17.0 0.0 0.027 13.8 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 ETS85387.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 ETS85387.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 ETS85387.1 - 0.079 13.1 0.3 0.26 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain EH_Signature PF15611.1 ETS85387.1 - 0.091 11.7 1.9 0.14 11.1 1.3 1.3 1 0 0 1 1 1 0 EH_Signature domain SprA-related PF12118.3 ETS85389.1 - 0.027 13.8 30.8 0.034 13.4 21.3 1.1 1 0 0 1 1 1 0 SprA-related family CAF-1_p150 PF11600.3 ETS85389.1 - 0.042 13.2 64.8 0.053 12.8 44.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 ETS85389.1 - 0.19 10.1 54.3 0.24 9.8 37.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETS85389.1 - 0.23 10.6 44.8 0.27 10.3 31.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOBP PF15279.1 ETS85389.1 - 0.72 10.1 11.4 0.87 9.9 7.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ebola_NP PF05505.7 ETS85389.1 - 1.7 6.6 14.4 1.9 6.4 10.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein MMR1 PF08505.5 ETS85389.1 - 3.8 7.4 20.2 5.2 7.0 14.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nop14 PF04147.7 ETS85389.1 - 3.8 5.2 42.9 4.6 5.0 29.8 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.6 ETS85389.1 - 5.4 5.5 20.3 6.2 5.3 14.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BTV_NS2 PF04514.7 ETS85389.1 - 6.1 5.6 30.9 8.3 5.1 21.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4551 PF15087.1 ETS85389.1 - 7.7 4.7 14.3 8.9 4.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 ETS85389.1 - 9.2 3.7 20.5 10 3.6 14.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sod_Fe_C PF02777.13 ETS85390.1 - 4.3e-35 119.7 0.3 6.9e-35 119.0 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 ETS85390.1 - 1.2e-32 111.9 3.4 1.2e-32 111.9 0.6 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tyrosinase PF00264.15 ETS85391.1 - 3.9e-35 122.0 6.7 5.4e-35 121.5 4.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.17 ETS85392.1 - 6.8e-17 61.1 0.0 8.6e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 ETS85393.1 - 1.4e-14 54.1 0.0 1.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS85393.1 - 5.8e-09 35.7 0.0 1.1e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS85393.1 - 1.3e-06 28.9 0.0 0.00012 22.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS85393.1 - 1.5e-06 28.6 0.0 7.4e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85393.1 - 3.8e-05 24.1 0.0 9.1e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS85393.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Phosphodiest PF01663.17 ETS85394.1 - 2.3e-35 122.5 0.0 5.4e-35 121.3 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.13 ETS85395.1 - 0.00046 19.1 0.0 0.00093 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal-3-0_sulfotr PF06990.6 ETS85395.1 - 0.052 12.2 0.8 0.61 8.6 0.0 2.0 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase Zn_clus PF00172.13 ETS85396.1 - 2.8e-10 39.9 8.1 5e-10 39.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_p26 PF04766.7 ETS85397.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein NUP PF06516.6 ETS85398.1 - 2.6e-110 368.1 0.1 3.7e-110 367.6 0.1 1.2 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) HATPase_c PF02518.21 ETS85400.1 - 4.7e-22 77.8 0.0 1.5e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS85400.1 - 5.1e-20 71.5 0.0 4e-19 68.6 0.0 2.5 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 ETS85400.1 - 1.6e-11 44.0 0.0 4.8e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pec_lyase_C PF00544.14 ETS85401.1 - 1.6e-19 70.1 1.2 3e-19 69.2 0.8 1.5 1 0 0 1 1 1 1 Pectate lyase Isochorismatase PF00857.15 ETS85402.1 - 6.1e-23 81.6 0.1 9.9e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Calc_CGRP_IAPP PF00214.14 ETS85403.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family HEAT_2 PF13646.1 ETS85405.1 - 0.0011 19.1 1.6 0.04 14.1 0.3 3.9 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 ETS85405.1 - 0.0013 18.6 2.1 0.19 11.9 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat mRNA_cap_enzyme PF01331.14 ETS85406.1 - 2e-55 187.4 0.0 2.7e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 ETS85406.1 - 6.5e-23 81.0 0.1 1.2e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 ETS85406.1 - 1.4e-06 27.8 1.1 3.3e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 ATP dependent DNA ligase domain FtsQ PF03799.10 ETS85406.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsQ MFS_1 PF07690.11 ETS85407.1 - 3.2e-31 108.3 44.5 2.7e-30 105.2 31.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 ETS85408.1 - 7.9e-09 34.5 1.9 1.2e-08 34.0 1.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain EST1_DNA_bind PF10373.4 ETS85408.1 - 0.022 13.9 0.4 0.035 13.3 0.3 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain AA_permease_2 PF13520.1 ETS85409.1 - 1.2e-69 234.9 41.3 1.5e-69 234.6 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 ETS85409.1 - 3.5e-06 25.7 17.0 3.5e-06 25.7 11.8 1.9 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein DUF1600 PF07667.6 ETS85409.1 - 6 6.9 12.5 0.66 10.0 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) PIRT PF15099.1 ETS85409.1 - 6.5 5.9 9.2 3.1 7.0 1.4 2.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family NAD_binding_10 PF13460.1 ETS85410.1 - 1.1e-11 45.0 0.3 2e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS85410.1 - 2.5e-09 36.7 0.2 4.4e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Peripla_BP_4 PF13407.1 ETS85410.1 - 1.5e-06 27.8 0.4 7.9e-06 25.4 0.0 2.0 1 1 1 2 2 2 1 Periplasmic binding protein domain Epimerase PF01370.16 ETS85410.1 - 0.044 13.2 0.0 0.49 9.7 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aa_trans PF01490.13 ETS85411.1 - 1.3e-49 168.7 36.2 1.5e-49 168.6 25.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asparaginase PF00710.15 ETS85413.1 - 1.3e-70 237.7 1.6 1.5e-70 237.5 1.1 1.0 1 0 0 1 1 1 1 Asparaginase DUF3632 PF12311.3 ETS85414.1 - 2.6e-34 118.6 2.2 4.8e-34 117.7 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MFS_1 PF07690.11 ETS85415.1 - 3.5e-33 114.7 78.7 2.9e-25 88.7 32.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 ETS85416.1 - 9e-27 93.8 0.0 2.4e-26 92.4 0.0 1.6 2 1 0 2 2 2 1 O-methyltransferase zf-C2H2 PF00096.21 ETS85417.1 - 3.3 8.2 7.1 0.19 12.1 1.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.20 ETS85418.1 - 6.1e-17 62.0 0.1 9.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85418.1 - 1.5e-10 41.0 0.1 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85418.1 - 0.017 14.5 0.1 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyoxalase_4 PF13669.1 ETS85418.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_28 PF00295.12 ETS85421.1 - 1.6e-48 165.3 7.5 2.6e-48 164.6 5.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 ABC_membrane PF00664.18 ETS85422.1 - 2e-35 122.5 14.9 2.7e-35 122.1 10.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 ETS85422.1 - 1.7e-33 115.8 0.0 2.9e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 ETS85422.1 - 4.5e-08 33.3 0.1 0.0012 18.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 ETS85422.1 - 7.1e-06 25.4 0.0 0.00085 18.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS85422.1 - 0.00013 21.9 0.1 0.00089 19.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS85422.1 - 0.00016 22.4 0.0 0.00038 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS85422.1 - 0.00024 21.2 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS85422.1 - 0.00031 20.6 0.0 0.0061 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 ETS85422.1 - 0.00071 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS85422.1 - 0.0012 18.7 0.0 0.0047 16.8 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 ETS85422.1 - 0.0031 17.0 0.1 0.012 15.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 ETS85422.1 - 0.0052 15.4 0.2 0.32 9.5 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 ETS85422.1 - 0.0059 16.9 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 ETS85422.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 ETS85422.1 - 0.012 15.7 0.0 0.11 12.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 ETS85422.1 - 0.013 15.0 0.0 0.068 12.7 0.0 2.2 2 2 1 3 3 3 0 AAA domain AAA_28 PF13521.1 ETS85422.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 ETS85422.1 - 0.023 14.0 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 ETS85422.1 - 0.028 14.1 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 ETS85422.1 - 0.038 13.9 0.3 0.36 10.7 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 ETS85422.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 ETS85422.1 - 0.061 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein T2SE PF00437.15 ETS85422.1 - 0.081 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 ETS85422.1 - 0.083 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETS85422.1 - 0.099 12.2 0.3 0.32 10.6 0.0 1.9 3 0 0 3 3 2 0 NACHT domain ATP-synt_ab PF00006.20 ETS85422.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.10 ETS85422.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Pyr_redox_2 PF07992.9 ETS85423.1 - 8.2e-16 58.4 0.0 0.00069 19.5 0.0 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS85423.1 - 7.2e-15 55.1 0.2 5.2e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS85423.1 - 6e-08 32.9 0.3 0.011 15.7 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS85423.1 - 9.7e-08 31.2 0.1 0.023 13.6 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS85423.1 - 2.5e-05 23.3 0.0 4.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 ETS85423.1 - 0.0043 17.2 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 ETS85423.1 - 0.0074 14.9 0.6 5.6 5.4 0.1 3.0 2 1 1 3 3 3 1 Tryptophan halogenase TrkA_N PF02254.13 ETS85423.1 - 0.015 15.2 0.2 0.38 10.7 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_2 PF00890.19 ETS85423.1 - 0.018 13.9 0.1 2.1 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 ETS85423.1 - 0.023 13.1 0.5 0.91 7.9 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS85423.1 - 0.025 13.5 0.4 0.22 10.4 0.0 2.6 2 2 2 4 4 4 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS85423.1 - 0.045 13.7 0.0 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 ETS85425.1 - 3.8e-35 121.2 27.1 3.8e-35 121.2 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 ETS85425.1 - 0.058 13.3 6.2 0.061 13.3 1.1 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AB MR_MLE_C PF13378.1 ETS85426.1 - 7.5e-18 64.5 0.3 1.7e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 ETS85426.1 - 6.3e-10 39.4 1.1 1.1e-09 38.6 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 ETS85426.1 - 0.038 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HUN PF08729.5 ETS85427.1 - 5.3e-14 51.8 2.0 1.6e-13 50.2 1.1 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 ETS85428.1 - 8.5e-30 102.4 0.0 1.6e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 ETS85428.1 - 1.2e-17 63.2 2.5 2.1e-17 62.4 1.7 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal GPP34 PF05719.6 ETS85429.1 - 8.8e-64 215.3 0.1 1.1e-63 215.0 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF1907 PF08925.6 ETS85430.1 - 1.3e-107 359.0 0.0 1.5e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) PA_decarbox PF05870.6 ETS85431.1 - 1.1e-07 31.4 0.5 1.9e-07 30.7 0.4 1.6 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Sugar_tr PF00083.19 ETS85432.1 - 1.4e-71 241.3 26.3 1.6e-71 241.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85432.1 - 1.2e-30 106.4 44.6 5.2e-28 97.7 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1422 PF07226.6 ETS85432.1 - 0.8 9.4 4.9 4.2 7.1 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) DUF3593 PF12159.3 ETS85432.1 - 4 7.2 6.5 1.4 8.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) adh_short PF00106.20 ETS85433.1 - 6.6e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85433.1 - 7.9e-24 84.7 0.0 3e-22 79.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85433.1 - 6.8e-13 48.6 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85433.1 - 0.00058 19.3 0.1 0.0017 17.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 ETS85434.1 - 2.5e-32 112.0 1.0 4.1e-32 111.4 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85434.1 - 3.7e-30 105.4 0.2 4.3e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85434.1 - 1.8e-11 44.0 0.1 2.8e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85434.1 - 1.8e-06 27.5 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 ETS85434.1 - 0.00064 19.4 1.1 0.0011 18.7 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb1_4 PF05000.12 ETS85434.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 3Beta_HSD PF01073.14 ETS85434.1 - 0.07 11.8 0.1 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 ETS85434.1 - 0.089 12.6 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydro_72 PF03198.9 ETS85436.1 - 6.4e-123 409.7 3.4 9.4e-123 409.1 2.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 ETS85436.1 - 1.4e-24 86.3 5.0 3.6e-24 85.0 3.5 1.8 1 0 0 1 1 1 1 X8 domain Macoilin PF09726.4 ETS85436.1 - 4.1 5.5 13.6 5.4 5.1 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein His_Phos_2 PF00328.17 ETS85437.1 - 6.7e-20 71.7 0.0 9.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tox-HNH-HHH PF15637.1 ETS85437.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF4232 PF14016.1 ETS85438.1 - 0.092 12.4 0.4 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Nucleo_P87 PF07267.6 ETS85439.1 - 0.63 8.6 6.2 0.75 8.4 4.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Borrelia_P83 PF05262.6 ETS85439.1 - 2.4 6.3 15.9 2.5 6.2 11.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hydrolase_like PF13242.1 ETS85440.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 HAD-hyrolase-like LRRC37AB_C PF14914.1 ETS85441.1 - 0.15 11.5 1.1 0.24 10.8 0.3 1.8 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MFS_1 PF07690.11 ETS85443.1 - 1.2e-47 162.3 34.5 2.8e-40 138.1 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 ETS85443.1 - 1e-05 23.8 2.1 0.053 11.5 1.0 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.11 ETS85443.1 - 0.0062 15.3 1.7 0.0084 14.8 0.0 2.0 2 2 0 2 2 2 1 BT1 family EphA2_TM PF14575.1 ETS85444.1 - 0.036 14.4 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.10 ETS85444.1 - 5.4 6.7 5.0 1.8 8.2 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Cupin_2 PF07883.6 ETS85445.1 - 1.1e-10 40.7 0.8 1.1e-10 40.7 0.6 1.9 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.17 ETS85445.1 - 2.3e-06 27.1 0.0 3.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Cupin GPI PF06560.6 ETS85445.1 - 0.00072 18.6 0.1 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) AraC_binding PF02311.14 ETS85445.1 - 0.0022 17.6 0.3 0.0041 16.8 0.1 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.17 ETS85445.1 - 0.009 16.2 0.2 0.076 13.2 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase FdtA PF05523.6 ETS85445.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal SURF6 PF04935.7 ETS85447.1 - 1.1e-48 165.3 43.2 1.1e-48 165.3 30.0 3.8 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 ETS85447.1 - 3.4e-20 71.8 1.9 3.4e-20 71.8 1.3 7.3 5 1 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 ApbA PF02558.11 ETS85448.1 - 0.024 14.0 0.1 0.063 12.7 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3918 PF13056.1 ETS85448.1 - 0.39 10.0 0.0 0.39 10.0 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3918) NAD_binding_8 PF13450.1 ETS85448.1 - 1.9 8.5 11.3 2 8.5 0.1 4.6 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain ABA_WDS PF02496.11 ETS85448.1 - 6.3 7.0 28.0 4.4 7.5 0.4 4.9 3 1 0 4 4 4 0 ABA/WDS induced protein MFS_1 PF07690.11 ETS85449.1 - 7.7e-41 139.9 49.9 3e-40 138.0 34.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PAN_4 PF14295.1 ETS85450.1 - 0.3 10.8 5.3 0.097 12.3 0.8 2.4 2 0 0 2 2 2 0 PAN domain PAN_2 PF08276.6 ETS85450.1 - 3 7.7 7.8 47 3.9 5.4 2.6 1 1 0 1 1 1 0 PAN-like domain Isochorismatase PF00857.15 ETS85451.1 - 1.4e-13 51.1 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF1237 PF06824.6 ETS85452.1 - 2.3e-159 530.5 0.0 2.6e-159 530.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF2434 PF10361.4 ETS85453.1 - 1.4e-120 401.8 5.9 1.9e-120 401.4 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Sporozoite_P67 PF05642.6 ETS85453.1 - 1.3 6.8 7.5 1.6 6.4 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2_4 PF13894.1 ETS85454.1 - 3.5e-06 26.9 13.2 0.00054 20.1 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS85454.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 ETS85454.1 - 1.3e-05 25.1 11.4 0.0063 16.8 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF1446 PF07287.6 ETS85455.1 - 6.3e-124 413.1 0.4 7.6e-124 412.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Polysacc_deac_1 PF01522.16 ETS85456.1 - 4.4e-27 94.1 0.0 6.6e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 ETS85456.1 - 7.1e-08 31.7 0.0 9e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_63 PF03200.11 ETS85456.1 - 0.019 12.8 0.1 0.022 12.6 0.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Zn_clus PF00172.13 ETS85457.1 - 2.1e-08 33.9 10.2 3.3e-08 33.2 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS85457.1 - 5.5e-06 25.4 0.1 1.2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.9 ETS85458.1 - 3.3e-55 187.2 0.1 3.8e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 ETS85458.1 - 0.025 14.6 0.6 0.32 11.0 0.0 2.9 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Cpn60_TCP1 PF00118.19 ETS85459.1 - 4.6e-148 493.8 0.1 5.2e-148 493.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.9 ETS85460.1 - 8.8e-28 97.2 0.0 8.9e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 ETS85460.1 - 9.9e-12 44.7 0.1 9.9e-12 44.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 ETS85460.1 - 1.5e-06 27.6 0.0 0.00015 21.0 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 ETS85460.1 - 5.8e-06 25.4 0.1 1.2e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS85460.1 - 1.5e-05 24.8 0.3 0.00016 21.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS85460.1 - 0.0066 16.3 0.6 0.063 13.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS85460.1 - 0.0082 16.2 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS85460.1 - 0.047 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 ETS85460.1 - 0.087 11.9 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_6 PF12697.2 ETS85460.1 - 0.12 12.2 2.5 1.1 9.0 1.7 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 ETS85461.1 - 2.6e-21 76.2 0.0 4.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85461.1 - 1.5e-08 34.6 0.1 2.7e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85461.1 - 2.3e-08 33.9 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85461.1 - 0.00015 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 ETS85461.1 - 0.00019 21.8 0.3 0.00047 20.5 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 ETS85461.1 - 0.00064 18.7 0.1 0.00089 18.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS85461.1 - 0.0016 18.5 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 ETS85461.1 - 0.04 13.9 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 ETS85461.1 - 0.057 13.0 0.3 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phytoreo_P8 PF07124.6 ETS85461.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 VID27 PF08553.5 ETS85462.1 - 0 1123.9 0.0 0 1123.6 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 ETS85462.1 - 0.27 9.0 12.5 0.41 8.5 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS85462.1 - 0.35 8.8 6.6 0.51 8.3 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_20 PF00982.16 ETS85463.1 - 5.4e-199 661.5 0.0 6.1e-199 661.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 ETS85463.1 - 0.012 15.1 0.2 0.043 13.2 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain 2-oxoacid_dh PF00198.18 ETS85465.1 - 6.1e-80 267.8 0.0 8.8e-80 267.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETS85465.1 - 3.1e-20 71.6 3.0 6.2e-20 70.6 2.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 ETS85465.1 - 2.9e-05 23.6 0.9 0.025 14.2 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 ETS85465.1 - 0.00042 20.6 0.8 0.48 10.8 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 ETS85465.1 - 0.00066 18.9 7.5 0.005 16.0 2.8 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 ETS85465.1 - 0.01 15.5 0.3 0.37 10.5 0.0 2.8 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF3614 PF12267.3 ETS85465.1 - 0.03 14.5 1.0 0.11 12.7 0.0 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3614) GCV_H PF01597.14 ETS85465.1 - 0.042 13.5 0.6 0.11 12.1 0.3 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein Trypan_PARP PF05887.6 ETS85465.1 - 0.84 9.4 17.5 1.4 8.7 12.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SpoIIIAH PF12685.2 ETS85465.1 - 1.3 8.4 13.5 2.6 7.4 6.3 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Histone PF00125.19 ETS85467.1 - 8.7e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS85467.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DLIC PF05783.6 ETS85467.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Histone PF00125.19 ETS85468.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS85468.1 - 3.7e-05 23.7 0.0 9.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 ETS85468.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 ETS85468.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 ETS85468.1 - 0.043 14.3 0.7 0.059 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 ETS85469.1 - 2.6e-11 43.0 0.0 8e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 ETS85469.1 - 2.2e-08 33.7 1.1 5.5e-08 32.4 0.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 ETS85469.1 - 0.033 14.0 0.3 0.033 14.0 0.2 3.1 2 1 1 3 3 3 0 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 ETS85470.1 - 9.2e-92 307.1 0.0 1.4e-91 306.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 ETS85471.1 - 7.6e-25 86.4 2.7 7.6e-25 86.4 1.9 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 ETS85471.1 - 1.9e-10 40.5 2.2 1.9e-10 40.5 1.5 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS85471.1 - 3.2e-09 36.6 8.0 1.5e-08 34.5 1.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS85471.1 - 5.3e-06 26.4 6.0 0.00059 19.9 1.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 ETS85471.1 - 0.00025 21.2 6.1 0.039 14.3 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETS85471.1 - 0.0021 17.8 2.0 0.3 11.0 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 ETS85471.1 - 0.0031 17.7 2.4 0.12 12.8 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger RPT PF13446.1 ETS85471.1 - 0.021 14.2 0.3 0.071 12.5 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF2387 PF09526.5 ETS85471.1 - 0.066 13.1 3.9 0.39 10.6 2.7 2.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) SPX PF03105.14 ETS85472.1 - 1.2e-32 113.8 0.5 3.3e-32 112.3 0.3 1.5 2 0 0 2 2 2 1 SPX domain zf-C3HC4 PF00097.20 ETS85472.1 - 1.1e-07 31.3 7.9 2.5e-07 30.2 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 ETS85472.1 - 3.9e-07 29.8 8.7 9e-07 28.6 6.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 ETS85472.1 - 5.1e-06 26.2 9.0 9.9e-06 25.2 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 ETS85472.1 - 5.7e-06 25.9 5.0 1.1e-05 24.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS85472.1 - 1.3e-05 25.0 10.3 2.7e-05 24.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS85472.1 - 1.8e-05 24.3 6.6 3.8e-05 23.3 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 ETS85472.1 - 0.00013 21.5 5.1 0.00046 19.8 3.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 ETS85472.1 - 0.084 12.6 4.1 0.25 11.1 2.8 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 ETS85472.1 - 0.18 11.6 1.8 0.4 10.5 1.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 ETS85472.1 - 0.48 10.0 8.2 0.079 12.5 2.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 ETS85472.1 - 0.64 9.5 5.8 0.8 9.2 1.4 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-Nse PF11789.3 ETS85472.1 - 0.78 9.3 3.3 2 8.0 2.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cys_Met_Meta_PP PF01053.15 ETS85473.1 - 1.6e-36 125.4 0.0 2.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS85473.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Mito_carr PF00153.22 ETS85475.1 - 7.4e-71 233.9 8.4 2.5e-23 81.5 0.7 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Gly_reductase PF09338.6 ETS85475.1 - 0.098 10.8 0.1 0.17 10.0 0.1 1.4 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits DUF2796 PF10986.3 ETS85477.1 - 0.007 16.3 4.4 0.013 15.5 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) Hox9_act PF04617.8 ETS85477.1 - 0.041 14.0 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Hox9 activation region CDC45 PF02724.9 ETS85477.1 - 0.054 11.5 7.1 0.063 11.2 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.4 ETS85477.1 - 0.071 13.1 6.7 0.34 10.9 3.6 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) LigT_PEase PF02834.11 ETS85477.1 - 0.084 12.8 0.5 27 4.8 0.0 3.3 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF2457 PF10446.4 ETS85477.1 - 0.088 11.5 24.9 0.15 10.7 17.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 ETS85477.1 - 0.094 12.4 14.2 0.2 11.3 9.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 ETS85477.1 - 0.33 10.4 15.1 0.63 9.5 10.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin DivIVA PF05103.8 ETS85477.1 - 0.54 10.3 11.2 0.15 12.0 0.7 2.6 2 0 0 2 2 2 0 DivIVA protein NOA36 PF06524.7 ETS85477.1 - 0.57 9.3 14.9 0.9 8.7 10.3 1.3 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 ETS85477.1 - 0.64 8.8 7.0 1 8.1 4.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 ETS85477.1 - 0.65 8.7 4.5 1 8.1 3.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein RRN3 PF05327.6 ETS85477.1 - 0.69 7.9 7.2 0.91 7.5 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 ETS85477.1 - 1.2 7.7 3.7 1.5 7.4 2.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RXT2_N PF08595.6 ETS85477.1 - 1.9 8.2 11.2 3.6 7.3 7.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal IncA PF04156.9 ETS85477.1 - 2.8 7.4 14.0 0.34 10.5 3.1 2.8 2 1 0 2 2 2 0 IncA protein Nop14 PF04147.7 ETS85477.1 - 2.8 5.7 18.7 4.2 5.1 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 ETS85477.1 - 3.4 7.2 21.9 0.25 10.9 9.5 2.8 3 1 0 3 3 3 0 Sigma-70, non-essential region FYDLN_acid PF09538.5 ETS85477.1 - 5.4 7.6 23.4 17 6.0 16.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.5 ETS85477.1 - 9.7 6.1 11.3 0.84 9.6 3.9 2.1 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DnaJ PF00226.26 ETS85478.1 - 1e-23 82.8 0.9 1e-23 82.8 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 ETS85478.1 - 5.1e-19 67.6 11.9 1.8e-10 40.2 0.1 5.1 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 ETS85478.1 - 3e-13 48.7 0.1 0.00018 20.9 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85478.1 - 2.5e-12 46.2 7.9 0.0045 17.5 0.3 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 ETS85478.1 - 5.9e-11 42.0 0.1 0.00011 21.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85478.1 - 1.2e-10 41.7 11.2 0.042 14.5 0.5 5.2 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS85478.1 - 2e-10 39.7 12.7 0.012 15.4 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS85478.1 - 1.7e-09 36.8 0.1 0.005 16.5 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS85478.1 - 2.4e-07 30.4 0.7 0.0015 18.5 0.0 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS85478.1 - 4.5e-06 26.7 11.6 0.27 11.7 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS85478.1 - 4.7e-06 26.8 7.8 0.032 14.5 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85478.1 - 1.4e-05 24.5 0.9 0.0031 17.2 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS85478.1 - 5.3e-05 23.0 5.3 0.51 10.3 0.0 4.8 3 3 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS85478.1 - 0.00027 21.0 7.9 0.07 13.2 0.1 4.5 2 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4208 PF13907.1 ETS85478.1 - 0.092 12.9 1.8 0.27 11.4 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) TPR_20 PF14561.1 ETS85478.1 - 0.1 12.7 1.8 1 9.5 0.0 3.4 3 3 1 4 4 4 0 Tetratricopeptide repeat DUF3368 PF11848.3 ETS85478.1 - 0.1 12.1 0.7 1.8 8.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Vac14_Fig4_bd PF11916.3 ETS85479.1 - 1.3e-83 278.5 8.0 1.3e-83 278.5 5.5 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 ETS85479.1 - 2.1e-44 149.8 0.0 1.3e-42 144.1 0.0 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 ETS85479.1 - 7.9e-09 35.7 3.1 0.00011 22.5 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 ETS85479.1 - 2.2e-07 30.4 2.9 0.00041 20.2 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 ETS85479.1 - 1.7e-05 24.9 1.2 0.071 13.3 0.0 4.3 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 ETS85479.1 - 0.00014 21.7 0.7 0.63 9.8 0.0 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 ETS85479.1 - 0.098 12.5 0.0 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.19 ETS85480.1 - 3.8e-39 134.6 24.7 5.2e-39 134.2 17.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 ETS85480.1 - 3.1e-11 42.9 0.0 6.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_dim PF02852.17 ETS85481.1 - 2.7e-41 140.0 0.0 9.9e-41 138.2 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 ETS85481.1 - 2.8e-38 131.8 15.6 6.3e-37 127.4 10.8 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS85481.1 - 2.1e-22 79.3 11.9 2.6e-20 72.6 0.8 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85481.1 - 2.8e-10 40.0 4.8 1.4e-05 25.0 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS85481.1 - 2.9e-10 39.8 7.5 1.3e-09 37.7 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS85481.1 - 6.7e-09 36.1 0.8 1.6e-05 25.0 0.3 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS85481.1 - 6.7e-09 35.1 14.2 5e-05 22.3 0.1 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 ETS85481.1 - 5.1e-08 32.1 11.1 1.3e-06 27.5 3.1 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 ETS85481.1 - 2.5e-07 30.0 5.5 8.1e-06 25.0 0.1 2.6 2 1 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 ETS85481.1 - 2.8e-07 29.7 14.5 2.9e-07 29.6 3.2 3.2 2 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 ETS85481.1 - 6.7e-06 24.8 14.4 0.00018 20.0 2.0 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 ETS85481.1 - 6.6e-05 22.1 5.8 0.015 14.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.16 ETS85481.1 - 0.00011 21.7 3.4 0.06 12.9 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 ETS85481.1 - 0.00054 18.9 0.1 0.13 11.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 ETS85481.1 - 0.0091 14.9 3.4 0.023 13.6 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETS85481.1 - 0.093 12.9 6.4 1.9 8.7 0.5 3.0 2 2 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 ETS85481.1 - 0.79 9.3 7.4 0.28 10.8 0.4 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 ETS85481.1 - 3.8 6.0 7.1 0.46 9.0 1.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MIF4G PF02854.14 ETS85482.1 - 1.1e-18 67.4 0.1 1.8e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 ETS85482.1 - 7.6e-10 38.5 0.3 5.2e-08 32.5 0.0 3.1 3 0 0 3 3 3 1 MA3 domain RRM_1 PF00076.17 ETS85483.1 - 3.8e-33 112.9 0.0 2.3e-16 59.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS85483.1 - 2.4e-27 94.6 0.0 1.1e-12 47.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS85483.1 - 4.3e-13 48.8 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 ETS85483.1 - 0.0011 18.3 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RRM_3 PF08777.6 ETS85483.1 - 0.048 13.5 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 ETS85483.1 - 0.1 12.3 0.0 3.3 7.5 0.0 2.9 3 1 0 3 3 3 0 Limkain b1 COQ9 PF08511.6 ETS85484.1 - 2.1e-26 91.1 0.1 6e-26 89.7 0.0 1.7 2 0 0 2 2 2 1 COQ9 SMC_N PF02463.14 ETS85485.1 - 3e-28 98.5 0.4 1.4e-27 96.4 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS85485.1 - 2.2e-12 47.7 23.9 2.2e-12 47.7 16.6 4.9 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETS85485.1 - 2e-08 34.5 0.0 1.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 ETS85485.1 - 1.6e-05 24.8 0.0 7.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.1 ETS85485.1 - 2.1e-05 24.3 0.1 0.0013 18.5 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 ETS85485.1 - 0.00011 21.4 0.2 0.00011 21.4 0.1 2.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETS85485.1 - 0.00027 20.4 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS85485.1 - 0.095 13.0 0.2 0.095 13.0 0.1 5.7 3 2 0 3 3 3 0 ABC transporter Laminin_II PF06009.7 ETS85485.1 - 3 7.6 37.1 0.018 14.8 1.0 6.3 3 2 4 7 7 7 0 Laminin Domain II SGT1 PF07093.6 ETS85486.1 - 7.6e-139 463.7 37.9 2.6e-137 458.7 26.3 2.0 1 1 0 1 1 1 1 SGT1 protein AAA PF00004.24 ETS85487.1 - 3.3e-39 134.1 0.0 6.3e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS85487.1 - 3.5e-06 27.2 1.0 8.9e-05 22.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.5 ETS85487.1 - 9e-06 25.4 0.0 6.2e-05 22.8 0.0 2.5 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 ETS85487.1 - 3.1e-05 23.1 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 ETS85487.1 - 4.8e-05 23.4 0.3 0.0021 18.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 ETS85487.1 - 0.00039 19.2 0.0 0.00072 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 ETS85487.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 ETS85487.1 - 0.0014 18.3 0.0 0.004 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS85487.1 - 0.0015 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 ETS85487.1 - 0.0018 17.9 0.8 0.026 14.2 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 ETS85487.1 - 0.0034 16.5 0.1 0.0076 15.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 ETS85487.1 - 0.0062 15.9 0.6 0.21 10.9 0.1 2.8 1 1 2 3 3 3 1 AAA domain DUF815 PF05673.8 ETS85487.1 - 0.0071 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETS85487.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS85487.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS85487.1 - 0.015 16.0 0.1 0.13 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 ETS85487.1 - 0.02 14.4 0.0 0.23 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS85487.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 ETS85487.1 - 0.029 13.4 0.9 0.54 9.3 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin AAA_28 PF13521.1 ETS85487.1 - 0.065 13.1 0.4 0.23 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 ETS85487.1 - 0.075 12.6 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 ETS85487.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Arch_ATPase PF01637.13 ETS85487.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 ETS85487.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 ETS85487.1 - 0.17 11.3 0.0 0.38 10.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_S17 PF00366.15 ETS85488.1 - 0.0001 22.2 0.8 0.00031 20.7 0.5 1.8 1 0 0 1 1 1 1 Ribosomal protein S17 MBOAT_2 PF13813.1 ETS85488.1 - 0.055 13.5 0.2 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family DUF1768 PF08719.6 ETS85488.1 - 0.12 12.0 4.3 2 8.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) adh_short PF00106.20 ETS85489.1 - 6.3e-19 68.4 1.8 9.4e-19 67.9 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85489.1 - 1.5e-12 47.5 0.8 2.1e-12 47.0 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF790 PF05626.6 ETS85489.1 - 0.036 12.5 0.0 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Ribosomal_S30AE PF02482.14 ETS85489.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein EMG1 PF03587.9 ETS85490.1 - 1.5e-77 259.5 0.0 1.7e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.24 ETS85492.1 - 6.6e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 ETS85492.1 - 0.14 9.6 0.1 0.23 8.9 0.0 1.2 1 0 0 1 1 1 0 Prominin DUF2013 PF09431.5 ETS85493.1 - 1.5e-50 170.5 2.7 1.5e-50 170.5 1.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Xpo1 PF08389.7 ETS85495.1 - 4.3e-08 33.2 0.5 5.7e-06 26.3 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 ETS85495.1 - 1.1e-06 28.4 1.7 2.7e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Con-6 PF10346.4 ETS85495.1 - 0.17 11.2 0.6 0.36 10.2 0.4 1.5 1 0 0 1 1 1 0 Conidiation protein 6 WD40 PF00400.27 ETS85496.1 - 0.00021 21.0 2.5 1.2 9.1 0.0 4.0 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF1917 PF08939.5 ETS85497.1 - 3.3e-58 197.3 0.1 5.5e-58 196.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 ETS85498.1 - 1.1e-19 70.1 0.0 1.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ETS85498.1 - 1.9e-11 44.1 0.0 2.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS85498.1 - 2.4e-11 43.6 0.0 3.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS85498.1 - 5.2e-10 38.9 0.0 7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 ETS85498.1 - 1.5e-09 37.8 0.0 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS85498.1 - 8.5e-09 35.7 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS85498.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS85498.1 - 6.4e-05 22.9 0.0 9.6e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS85498.1 - 0.00043 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase LCAT PF02450.10 ETS85499.1 - 4.9e-94 315.4 0.1 5.9e-94 315.2 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 ETS85499.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family THUMP PF02926.12 ETS85500.1 - 5.8e-11 42.4 0.2 1.8e-10 40.9 0.2 1.7 1 1 0 1 1 1 1 THUMP domain MFS_1 PF07690.11 ETS85502.1 - 5.3e-43 147.0 57.9 1.9e-42 145.2 38.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily COG6 PF06419.6 ETS85503.1 - 4.5e-222 738.5 7.9 5.1e-222 738.3 5.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 ETS85503.1 - 0.0012 17.7 2.8 0.0012 17.7 1.9 2.3 3 0 0 3 3 3 1 RmuC family COG2 PF06148.6 ETS85503.1 - 0.0031 17.3 1.0 0.012 15.4 0.7 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 ETS85503.1 - 0.0083 15.7 2.9 0.25 10.9 1.1 3.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF1043 PF06295.7 ETS85503.1 - 0.041 13.5 2.2 0.078 12.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF948 PF06103.6 ETS85503.1 - 1.2 9.0 5.1 0.54 10.1 0.5 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG9 PF04109.11 ETS85504.1 - 2.2e-146 487.5 1.8 3e-146 487.0 1.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Gar1 PF04410.9 ETS85505.1 - 1.4e-43 148.0 0.1 1.4e-43 148.0 0.1 1.9 1 1 0 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 ETS85506.1 - 1.8e-43 148.1 0.1 3.4e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS85506.1 - 1.9e-19 69.4 0.1 4.5e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 ETS85506.1 - 3e-11 43.0 0.0 6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 ETS85506.1 - 9.2e-11 41.4 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain CDP-OH_P_transf PF01066.16 ETS85507.1 - 1.3e-13 51.0 2.5 2.5e-13 50.1 1.7 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.3 ETS85508.1 - 1.1e-170 567.6 0.0 1.4e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 ETS85508.1 - 8.5e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 ETS85508.1 - 0.0014 18.6 0.2 0.0027 17.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 ETS85508.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 ETS85509.1 - 1.2e-08 34.3 0.0 1.2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Whi5 like Syndecan PF01034.15 ETS85510.1 - 0.046 13.3 0.4 0.089 12.4 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 ETS85510.1 - 0.11 11.8 5.0 0.86 8.9 3.5 2.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 ETS85510.1 - 0.46 10.0 7.6 0.93 9.0 0.0 2.3 2 0 0 2 2 2 0 Rifin/stevor family Plasmodium_Vir PF05795.6 ETS85510.1 - 1.1 8.3 11.5 0.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Peptidase_C14 PF00656.17 ETS85512.1 - 1.7e-71 240.8 0.0 2.2e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Pro-rich PF15240.1 ETS85512.1 - 0.36 10.9 34.3 0.63 10.1 23.8 1.3 1 0 0 1 1 1 0 Proline-rich PAT1 PF09770.4 ETS85512.1 - 0.5 8.5 17.4 0.71 8.0 12.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Microtub_assoc PF07989.6 ETS85513.1 - 2.6e-27 94.4 4.0 2.6e-27 94.4 2.7 14.6 10 5 9 19 19 18 1 Microtubule associated PACT_coil_coil PF10495.4 ETS85513.1 - 5.1e-12 45.5 1.9 2.2e-11 43.5 1.3 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TPR_MLP1_2 PF07926.7 ETS85513.1 - 6.2e-07 29.2 33.9 3.8e-05 23.4 14.0 13.3 4 3 5 10 10 10 4 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 ETS85513.1 - 3.3e-06 26.5 196.5 0.0025 17.1 9.5 9.0 2 2 5 8 8 7 4 Mechanosensitive ion channel porin domain DUF3584 PF12128.3 ETS85513.1 - 7.9e-05 20.2 30.6 7.9e-05 20.2 21.2 5.3 2 1 3 5 5 5 2 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 ETS85513.1 - 0.00017 21.4 198.7 0.00034 20.4 20.8 11.3 2 2 9 11 11 10 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 ETS85513.1 - 0.00017 21.2 220.8 0.00069 19.2 17.8 10.9 1 1 8 9 9 8 3 IncA protein CCDC155 PF14662.1 ETS85513.1 - 0.00031 20.3 18.6 0.00031 20.3 12.9 9.7 2 1 9 11 11 9 2 Coiled-coil region of CCDC155 AAA_13 PF13166.1 ETS85513.1 - 0.00035 19.1 143.8 0.013 14.0 16.1 6.7 1 1 5 6 6 6 3 AAA domain Spc7 PF08317.6 ETS85513.1 - 0.00058 18.6 14.1 0.00058 18.6 9.8 9.3 1 1 9 10 10 10 6 Spc7 kinetochore protein DUF1664 PF07889.7 ETS85513.1 - 0.0011 18.7 4.4 0.0011 18.7 3.1 11.0 7 2 4 11 11 10 2 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 ETS85513.1 - 0.0019 18.0 35.7 0.0019 18.0 24.8 12.3 2 1 10 13 13 12 5 Tropomyosin like HALZ PF02183.13 ETS85513.1 - 0.013 15.1 0.8 0.013 15.1 0.6 12.9 16 0 0 16 16 15 0 Homeobox associated leucine zipper DUF4634 PF15465.1 ETS85513.1 - 0.25 11.5 5.1 2.8 8.1 0.3 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) Reo_sigmaC PF04582.7 ETS85513.1 - 0.69 9.0 66.1 0.16 11.1 1.2 8.1 1 1 3 8 8 8 0 Reovirus sigma C capsid protein Filament PF00038.16 ETS85513.1 - 1.2 8.4 189.8 0.56 9.6 12.8 9.4 2 1 6 8 8 8 0 Intermediate filament protein GAS PF13851.1 ETS85513.1 - 5.8 6.0 178.0 0.16 11.1 16.5 10.3 2 2 8 10 10 10 0 Growth-arrest specific micro-tubule binding Transglut_core2 PF13369.1 ETS85514.1 - 1.7e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 ETS85514.1 - 2.3e-10 40.0 0.2 6.1e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 ETS85514.1 - 4.5e-09 36.1 0.0 9.9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 ETS85514.1 - 1.1e-06 28.1 1.4 2.2e-06 27.1 0.0 2.3 3 0 0 3 3 3 1 F-box domain TPP_enzyme_N PF02776.13 ETS85515.1 - 2.3e-33 115.1 0.1 4.6e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS85515.1 - 6.1e-28 97.2 0.0 1.2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 ETS85515.1 - 3.4e-15 55.9 0.0 1.1e-13 51.0 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAA_hydrolase PF01557.13 ETS85516.1 - 3.5e-40 137.7 0.0 4.2e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_C12 PF01088.16 ETS85517.1 - 3.5e-53 179.9 0.0 2.7e-38 131.3 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1989 PF09347.5 ETS85519.1 - 3.2e-50 169.7 0.0 4e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) CoA_trans PF01144.18 ETS85520.1 - 2.5e-98 327.5 1.2 2.4e-60 203.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Nrap PF03813.9 ETS85521.1 - 2.7e-288 958.6 0.0 3.1e-288 958.4 0.0 1.0 1 0 0 1 1 1 1 Nrap protein SRP72 PF08492.7 ETS85521.1 - 0.013 15.9 0.1 0.09 13.1 0.0 2.4 2 0 0 2 2 2 0 SRP72 RNA-binding domain Evr1_Alr PF04777.8 ETS85522.1 - 3e-28 97.5 2.4 5.5e-28 96.7 0.4 1.9 2 0 0 2 2 2 1 Erv1 / Alr family HoxA13_N PF12284.3 ETS85522.1 - 0.024 14.7 2.8 0.049 13.7 2.0 1.6 1 0 0 1 1 1 0 Hox protein A13 N terminal HEM4 PF02602.10 ETS85523.1 - 8.1e-35 120.1 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Fungal_trans_2 PF11951.3 ETS85524.1 - 2e-08 33.2 0.3 4.7e-08 32.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85524.1 - 2.6e-06 27.2 12.3 2.6e-06 27.2 8.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3318 PF11780.3 ETS85525.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) DUF3681 PF12442.3 ETS85525.1 - 0.06 13.5 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) Sec23_trunk PF04811.10 ETS85526.1 - 6.2e-71 238.6 0.0 1e-70 237.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 ETS85526.1 - 1.2e-23 82.5 0.0 3.4e-22 77.8 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 ETS85526.1 - 2.7e-18 66.2 0.1 5.5e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 ETS85526.1 - 1.8e-17 62.5 5.1 3.2e-17 61.8 3.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 ETS85526.1 - 5.2e-10 38.8 0.0 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 ETS85526.1 - 0.21 11.5 0.7 0.49 10.3 0.5 1.5 1 0 0 1 1 1 0 Testis-expressed 12 Pkinase PF00069.20 ETS85527.1 - 3.3e-74 249.3 0.0 4.5e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85527.1 - 9.3e-32 110.0 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS85527.1 - 0.00057 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS85527.1 - 0.0017 17.4 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS85527.1 - 0.0098 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS85527.1 - 0.044 12.6 0.1 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 ETS85527.1 - 0.08 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 ETS85527.1 - 0.1 11.9 0.3 0.36 10.2 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain adh_short PF00106.20 ETS85528.1 - 5.8e-08 32.8 0.2 1.2e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85528.1 - 3.3e-06 27.0 0.0 6.5e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TLD PF07534.11 ETS85529.1 - 5.3e-23 81.5 0.0 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 TLD DIOX_N PF14226.1 ETS85531.1 - 4.6e-21 75.5 0.0 2.2e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS85531.1 - 2.8e-12 46.7 0.0 4.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS85532.1 - 1.9e-19 69.5 51.8 7.1e-15 54.5 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EI24 PF07264.6 ETS85534.1 - 1.2e-07 31.4 2.3 1.2e-07 31.4 1.6 2.1 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) ARD PF03079.9 ETS85535.1 - 0.13 12.1 1.6 20 5.1 0.0 3.1 2 1 1 3 3 3 0 ARD/ARD' family Pkinase PF00069.20 ETS85536.1 - 2.2e-18 66.3 0.0 2.9e-17 62.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85536.1 - 3.4e-06 26.3 0.0 0.0078 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase MsyB PF13984.1 ETS85536.1 - 0.056 13.4 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 MsyB protein NUDIX PF00293.23 ETS85538.1 - 2.5e-18 65.9 0.0 3.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Met_10 PF02475.11 ETS85539.1 - 1.5e-05 24.6 0.0 9.4e-05 22.0 0.0 1.9 1 1 1 2 2 2 1 Met-10+ like-protein RhoGAP PF00620.22 ETS85539.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain Methyltransf_26 PF13659.1 ETS85539.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_6 PF13405.1 ETS85540.1 - 4.8e-08 32.2 0.5 0.0023 17.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 ETS85540.1 - 4.2e-06 26.7 0.3 4.2e-06 26.7 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 ETS85540.1 - 1.3e-05 24.1 1.3 3.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 ETS85540.1 - 0.0014 18.1 0.8 0.0035 16.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 ETS85540.1 - 0.0021 17.3 0.5 0.0057 15.9 0.0 1.9 2 0 0 2 2 2 1 EF hand ORC6 PF05460.8 ETS85541.1 - 5.2e-41 140.9 0.5 9e-41 140.1 0.4 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) OPT PF03169.10 ETS85543.1 - 1.2e-131 440.1 46.4 1.4e-131 439.9 32.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 ETS85544.1 - 1.3e-26 93.5 0.2 1.6e-26 93.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85544.1 - 2.9e-13 49.8 0.1 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS85544.1 - 1.5e-12 47.8 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS85544.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS85544.1 - 1.3e-05 24.2 0.0 1.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETS85544.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 ETS85544.1 - 0.074 13.3 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 ETS85544.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS85546.1 - 2.3e-11 43.3 0.1 4.4e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 ETS85546.1 - 0.00048 20.0 0.2 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85546.1 - 0.0005 20.0 1.2 0.0014 18.5 0.8 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS85546.1 - 0.0016 18.8 1.6 0.0016 18.8 1.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS85546.1 - 0.002 16.6 1.4 0.0025 16.3 0.5 1.4 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS85546.1 - 0.0032 16.4 2.1 0.092 11.6 1.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS85546.1 - 0.0088 14.9 1.9 0.019 13.8 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 ETS85546.1 - 0.037 13.1 0.1 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS85546.1 - 0.15 11.1 2.9 0.23 10.4 0.2 2.2 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Amino_oxidase PF01593.19 ETS85547.1 - 2.6e-44 152.0 0.0 3e-24 85.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS85547.1 - 2.8e-13 49.6 0.3 7e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS85547.1 - 2.7e-08 33.1 0.0 5.5e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS85547.1 - 1.3e-05 24.4 0.2 2.2e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 ETS85547.1 - 5.4e-05 22.2 0.2 0.0001 21.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS85547.1 - 7.2e-05 22.9 0.0 0.00056 20.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS85547.1 - 7.3e-05 21.9 0.3 0.00028 20.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS85547.1 - 0.00018 20.0 0.2 0.0028 16.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 ETS85547.1 - 0.0026 16.9 0.9 0.0042 16.2 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS85547.1 - 0.0033 17.8 0.2 0.0068 16.7 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85547.1 - 0.023 14.5 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS85547.1 - 0.032 13.6 0.1 0.11 11.9 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 ETS85547.1 - 0.043 12.6 0.1 0.071 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS85547.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain dsrm PF00035.20 ETS85548.1 - 5.8e-05 23.5 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 ETS85548.1 - 0.0056 16.9 0.1 0.011 16.0 0.1 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 ABC_tran PF00005.22 ETS85549.1 - 3.3e-48 163.4 0.1 2.9e-26 92.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS85549.1 - 2.4e-39 135.4 26.4 2.6e-28 99.2 8.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS85549.1 - 2.5e-15 56.3 1.6 3.3e-05 23.2 0.5 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS85549.1 - 9.4e-12 45.4 0.4 0.0031 17.5 0.1 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 ETS85549.1 - 3.6e-07 30.3 2.3 0.0098 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 ETS85549.1 - 2.3e-06 26.9 2.0 0.0037 16.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS85549.1 - 6.2e-06 25.6 0.4 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS85549.1 - 2e-05 24.1 1.2 0.013 15.0 0.0 2.8 2 1 0 2 2 2 1 AAA-like domain T2SE PF00437.15 ETS85549.1 - 4.3e-05 22.5 0.5 0.28 10.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 ETS85549.1 - 5.8e-05 22.5 0.2 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 ETS85549.1 - 0.00011 22.7 0.5 0.17 12.3 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 ETS85549.1 - 0.00022 21.4 0.2 0.15 12.2 0.0 3.7 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 ETS85549.1 - 0.00035 20.5 0.9 0.75 9.7 0.4 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF815 PF05673.8 ETS85549.1 - 0.00035 19.5 0.1 0.13 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 ETS85549.1 - 0.00055 19.0 0.1 0.36 9.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 ETS85549.1 - 0.00057 19.6 0.3 0.35 10.5 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 ETS85549.1 - 0.00075 19.6 1.0 1.2 9.2 0.1 3.0 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 ETS85549.1 - 0.0011 18.8 1.6 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 ETS85549.1 - 0.0014 19.0 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 ETS85549.1 - 0.0015 17.6 0.0 0.61 9.0 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain ArgK PF03308.11 ETS85549.1 - 0.008 14.9 0.3 0.41 9.3 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 ETS85549.1 - 0.016 15.1 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 ETS85549.1 - 0.016 15.0 0.3 9.8 6.1 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 ETS85549.1 - 0.017 14.5 0.4 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 ETS85549.1 - 0.02 13.7 1.0 7.4 5.3 0.0 3.7 4 0 0 4 4 4 0 NB-ARC domain Adeno_IVa2 PF02456.10 ETS85549.1 - 0.023 13.3 0.1 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.4 ETS85549.1 - 0.028 13.0 0.5 3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 ETS85549.1 - 0.033 13.8 0.7 6.4 6.4 0.1 2.9 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETS85549.1 - 0.034 13.7 0.4 2.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 ETS85549.1 - 0.035 14.4 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS85549.1 - 0.037 14.2 0.1 8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 ETS85549.1 - 0.037 14.8 0.1 9.8 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 ETS85549.1 - 0.04 13.6 0.8 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 ETS85549.1 - 0.15 11.7 2.0 13 5.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 ETS85549.1 - 0.16 11.4 3.0 4.4 6.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 ETS85549.1 - 0.17 11.6 1.3 0.23 11.2 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 Pox_A32 PF04665.7 ETS85549.1 - 0.27 10.5 0.7 3.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_PrkA PF08298.6 ETS85549.1 - 0.39 9.3 0.2 8.8 4.9 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain LCCL PF03815.14 ETS85555.1 - 1.4e-19 69.8 0.0 2.5e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Dioxygenase_C PF00775.16 ETS85556.1 - 7.4e-16 57.9 0.2 7.5e-15 54.6 0.2 2.1 1 1 0 1 1 1 1 Dioxygenase RE_Eco47II PF09553.5 ETS85557.1 - 0.11 11.6 0.6 0.84 8.7 0.1 2.3 1 1 1 2 2 2 0 Eco47II restriction endonuclease Methyltransf_31 PF13847.1 ETS85558.1 - 8.1e-26 90.4 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85558.1 - 5.1e-25 87.7 0.0 9.1e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS85558.1 - 1.1e-17 63.8 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETS85558.1 - 1.6e-16 60.8 0.0 4.3e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS85558.1 - 1.4e-15 57.5 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS85558.1 - 6.2e-14 52.1 0.0 1.4e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS85558.1 - 6.7e-11 42.1 0.0 9.3e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS85558.1 - 5.6e-10 39.2 0.1 1.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS85558.1 - 9.9e-10 38.0 0.0 1.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 ETS85558.1 - 2e-06 26.9 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 ETS85558.1 - 2.5e-06 26.9 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 ETS85558.1 - 1.2e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 ETS85558.1 - 3.8e-05 22.8 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS85558.1 - 0.00036 19.7 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 ETS85558.1 - 0.00052 19.7 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 ETS85558.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 ETS85558.1 - 0.0017 19.1 0.1 0.0039 17.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain DREV PF05219.7 ETS85558.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GCD14 PF08704.5 ETS85558.1 - 0.0042 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_2 PF00891.13 ETS85558.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_29 PF03141.11 ETS85558.1 - 0.01 14.2 0.0 0.014 13.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_3 PF01596.12 ETS85558.1 - 0.013 14.5 0.1 0.022 13.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase GidB PF02527.10 ETS85558.1 - 0.018 14.1 0.0 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.6 ETS85558.1 - 0.042 12.5 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 ETS85558.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cupin_5 PF06172.6 ETS85559.1 - 4.2e-35 120.6 0.0 5.5e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Phage_holin PF04688.8 ETS85561.1 - 0.017 14.6 0.6 0.017 14.6 0.4 2.4 3 0 0 3 3 3 0 Phage lysis protein, holin GFO_IDH_MocA PF01408.17 ETS85562.1 - 1.1e-21 77.6 0.0 1.9e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3611 PF12263.3 ETS85563.1 - 0.038 13.3 1.3 1.7 7.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) p450 PF00067.17 ETS85564.1 - 2.4e-71 240.6 0.0 2.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clr5 PF14420.1 ETS85565.1 - 6.8e-17 61.1 1.8 1.5e-16 60.0 1.2 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 ETS85565.1 - 0.012 15.5 4.6 2.6 8.0 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85565.1 - 0.057 14.0 0.6 15 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 ETS85567.1 - 2.6e-12 47.0 0.1 7.3e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85567.1 - 5.5e-11 42.4 0.0 1.3e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS85567.1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 ETS85567.1 - 0.00095 17.7 0.0 0.0027 16.2 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) LIP PF03583.9 ETS85567.1 - 0.0032 16.7 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.15 ETS85567.1 - 0.016 14.7 0.3 0.047 13.2 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF1100 PF06500.6 ETS85567.1 - 0.023 13.2 0.0 0.047 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PhoPQ_related PF10142.4 ETS85567.1 - 0.052 12.0 0.0 0.29 9.5 0.0 1.9 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.6 ETS85567.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 ETS85567.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.9 ETS85567.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.13 ETS85567.1 - 0.21 10.8 2.5 0.89 8.7 0.0 2.9 3 1 0 4 4 4 0 Dienelactone hydrolase family DUF4091 PF13320.1 ETS85568.1 - 0.029 14.2 0.9 0.048 13.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) CBM_20 PF00686.14 ETS85569.1 - 2.2e-32 110.4 0.2 5.6e-32 109.2 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 ETS85569.1 - 1.2e-09 38.6 0.3 7.8e-07 29.5 0.2 2.5 1 1 0 1 1 1 1 Chitin binding domain Sporozoite_P67 PF05642.6 ETS85569.1 - 0.006 14.5 6.5 0.0076 14.1 4.5 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CBM_25 PF03423.8 ETS85569.1 - 0.039 14.0 0.1 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) GFA PF04828.9 ETS85571.1 - 8.3e-18 64.1 0.1 1.2e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NDUF_B8 PF05821.6 ETS85572.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Kelch_1 PF01344.20 ETS85573.1 - 0.085 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Kelch motif adh_short PF00106.20 ETS85574.1 - 6.7e-17 61.9 1.5 6.7e-17 61.9 1.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS85574.1 - 2.3e-08 33.9 1.2 3.3e-08 33.3 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85574.1 - 0.0022 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GTP1_OBG PF01018.17 ETS85574.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 GTP1/OBG Methyltransf_4 PF02390.12 ETS85574.1 - 0.057 12.4 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase SecY PF00344.15 ETS85575.1 - 2.2e-96 322.7 9.9 2.9e-96 322.4 6.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 ETS85575.1 - 9e-19 66.6 0.3 7.2e-18 63.8 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p IPPT PF01715.12 ETS85576.1 - 4.4e-55 186.4 0.2 6.3e-55 185.9 0.2 1.2 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 ETS85576.1 - 3.9e-06 27.1 0.0 0.11 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain zf-met PF12874.2 ETS85576.1 - 6.3e-06 26.2 0.2 1.3e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS85576.1 - 0.00016 21.7 0.2 0.00035 20.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.11 ETS85576.1 - 0.0006 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_17 PF13207.1 ETS85576.1 - 0.00077 20.2 0.2 0.0028 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS85576.1 - 0.0084 15.9 0.4 0.55 10.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 ETS85576.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 ETS85576.1 - 0.071 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 ETS85576.1 - 0.092 12.5 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain adh_short PF00106.20 ETS85577.1 - 1e-13 51.5 0.0 6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 ETS85577.1 - 0.017 14.7 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 KR domain Pyr_redox_3 PF13738.1 ETS85578.1 - 7.3e-22 78.4 0.0 1.9e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85578.1 - 1.6e-14 53.0 0.3 4.5e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 ETS85578.1 - 3.3e-13 49.9 0.0 5.1e-07 29.7 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS85578.1 - 2.3e-10 39.9 0.1 1.5e-08 34.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 ETS85578.1 - 2.3e-06 26.9 0.0 6.4e-05 22.1 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 ETS85578.1 - 1.5e-05 25.3 0.1 0.014 15.7 0.0 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85578.1 - 3.9e-05 23.5 0.0 0.00027 20.8 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 ETS85578.1 - 4.5e-05 22.6 0.1 0.0096 15.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 ETS85578.1 - 0.00048 19.8 0.1 0.051 13.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 ETS85578.1 - 0.012 14.5 0.1 0.024 13.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 ETS85578.1 - 0.023 13.5 0.1 0.7 8.6 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 ETS85578.1 - 0.024 13.7 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 ETS85578.1 - 0.026 13.9 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 ETS85578.1 - 0.03 12.8 0.1 0.11 10.9 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 ETS85578.1 - 0.041 13.4 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SSPI PF14098.1 ETS85578.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore protein I Shikimate_DH PF01488.15 ETS85578.1 - 0.095 12.8 0.0 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 ETS85578.1 - 0.13 11.6 0.2 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 ETS85578.1 - 0.14 12.4 0.0 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GMC_oxred_N PF00732.14 ETS85579.1 - 9.3e-61 205.5 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS85579.1 - 1.6e-31 109.4 0.0 9.3e-31 107.0 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS85579.1 - 0.00046 19.1 0.1 0.32 9.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 ETS85579.1 - 0.00064 18.8 0.1 0.0013 17.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 ETS85579.1 - 0.0009 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 ETS85579.1 - 0.0011 18.0 0.4 0.0081 15.0 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS85579.1 - 0.0023 17.9 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS85579.1 - 0.0047 17.0 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS85579.1 - 0.0058 15.1 0.1 0.26 9.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS85579.1 - 0.026 14.3 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS85579.1 - 0.049 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 ETS85579.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 ETS85579.1 - 0.21 10.4 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Elongin_A PF06881.6 ETS85580.1 - 0.0035 17.6 0.6 1.3 9.4 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A DnaJ_CXXCXGXG PF00684.14 ETS85580.1 - 0.029 14.4 1.0 0.042 13.9 0.7 1.2 1 0 0 1 1 1 0 DnaJ central domain p450 PF00067.17 ETS85581.1 - 3e-64 217.2 0.0 3.6e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 ETS85582.1 - 1.3e-16 61.3 0.0 2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Exo_endo_phos PF03372.18 ETS85583.1 - 1.4e-09 38.2 2.5 2.3e-09 37.5 1.5 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lipase_GDSL_2 PF13472.1 ETS85584.1 - 6.1e-05 23.2 2.4 0.00012 22.3 1.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS85584.1 - 6.5e-05 22.8 10.5 0.00012 21.9 7.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 ETS85585.1 - 1.9e-24 86.0 31.8 1.9e-24 86.0 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85585.1 - 6.5e-08 31.5 8.8 6.5e-08 31.5 6.1 3.4 3 0 0 3 3 3 1 Sugar (and other) transporter PAT1 PF09770.4 ETS85586.1 - 7.6 4.6 11.6 10 4.2 8.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MdcG PF10620.4 ETS85587.1 - 0.0093 15.5 0.1 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl-dephospho-CoA transferase MdcG IU_nuc_hydro PF01156.14 ETS85587.1 - 0.039 13.1 0.0 0.87 8.7 0.0 2.1 1 1 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase DUF4596 PF15363.1 ETS85587.1 - 0.16 11.9 0.3 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Amidase PF01425.16 ETS85588.1 - 3.9e-76 256.6 0.0 4.9e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Epimerase PF01370.16 ETS85589.1 - 7.2e-12 45.2 0.1 1.4e-11 44.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS85589.1 - 2.4e-11 43.9 3.4 6.5e-11 42.5 2.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding CbiJ PF02571.9 ETS85589.1 - 1.4e-06 27.8 0.6 2.2e-06 27.1 0.4 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK RmlD_sub_bind PF04321.12 ETS85589.1 - 2.4e-06 26.6 0.4 4.9e-06 25.6 0.2 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 ETS85589.1 - 3.5e-06 26.4 0.6 0.016 14.4 0.4 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.14 ETS85589.1 - 6.4e-05 21.7 0.0 0.00014 20.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS85589.1 - 0.0031 17.4 1.5 0.0065 16.4 1.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 ETS85589.1 - 0.011 15.3 1.2 0.39 10.2 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 ETS85589.1 - 0.013 15.8 0.1 0.032 14.6 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 ETS85589.1 - 0.017 14.0 0.4 0.15 10.9 0.3 2.2 1 1 0 1 1 1 0 Male sterility protein KR PF08659.5 ETS85589.1 - 0.021 14.4 3.2 0.059 13.0 0.4 2.6 3 1 0 3 3 3 0 KR domain NAD_Gly3P_dh_N PF01210.18 ETS85589.1 - 0.1 12.3 0.1 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 ETS85589.1 - 0.11 11.8 0.4 0.26 10.6 0.3 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 ETS85590.1 - 2.5e-15 56.4 1.2 4.4e-15 55.5 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85590.1 - 9.9e-06 24.6 3.0 2.9e-05 23.1 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 ETS85590.1 - 0.00015 21.4 1.6 0.00062 19.4 0.4 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 ETS85590.1 - 0.00019 21.7 3.2 0.0003 21.1 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85590.1 - 0.00041 20.2 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS85590.1 - 0.0016 17.3 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase GIDA PF01134.17 ETS85590.1 - 0.0099 14.7 0.6 0.017 13.9 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS85590.1 - 0.018 15.0 0.4 0.043 13.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS85590.1 - 0.026 13.0 0.4 0.045 12.2 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 ETS85590.1 - 0.044 13.1 0.3 0.12 11.7 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 ETS85590.1 - 0.055 13.4 1.3 0.29 11.1 0.2 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 ETS85590.1 - 0.083 12.9 0.3 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase M20_dimer PF07687.9 ETS85590.1 - 0.087 12.5 0.2 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Peptidase dimerisation domain AlaDh_PNT_C PF01262.16 ETS85590.1 - 0.1 12.1 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.6 ETS85591.1 - 6.6e-29 100.8 2.6 1.3e-28 99.8 1.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_8 PF13181.1 ETS85591.1 - 0.008 15.8 0.0 0.029 14.1 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85591.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.2 ETS85592.1 - 4.8e-24 84.5 0.3 5.2e-08 33.1 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS85592.1 - 2.6e-16 59.2 0.5 8.3e-05 22.6 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 ETS85592.1 - 8.7e-16 56.8 6.5 0.0003 20.4 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS85592.1 - 3.2e-14 52.9 0.5 7.6e-05 23.1 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85592.1 - 2.4e-10 39.6 0.5 0.0066 16.5 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat DUF4129 PF13559.1 ETS85592.1 - 0.077 12.9 2.2 8.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) NACHT PF05729.7 ETS85593.1 - 1.2e-07 31.4 0.0 4.4e-07 29.7 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS85593.1 - 1.9e-07 31.2 0.0 7.9e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS85593.1 - 3.3e-07 30.4 0.0 1.7e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 ETS85593.1 - 2.1e-05 24.7 1.4 0.00035 20.7 1.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 ETS85593.1 - 2.6e-05 23.3 0.0 0.094 11.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 ETS85593.1 - 4.1e-05 22.5 0.0 0.00011 21.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.13 ETS85593.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 ETS85593.1 - 0.12 13.1 0.2 0.48 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain Dyp_perox PF04261.7 ETS85594.1 - 6.3e-05 21.8 0.0 0.00055 18.7 0.0 2.5 3 0 0 3 3 3 1 Dyp-type peroxidase family HET PF06985.6 ETS85595.1 - 1.2e-25 90.3 0.7 2.6e-25 89.1 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.16 ETS85596.1 - 9.5e-58 196.0 0.1 3.9e-55 187.4 0.0 2.1 2 0 0 2 2 2 2 Amidase Cutinase PF01083.17 ETS85597.1 - 2.5e-34 118.5 0.5 2.9e-34 118.3 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS85597.1 - 0.00016 21.2 0.1 0.00027 20.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 ETS85597.1 - 0.019 14.8 0.1 0.027 14.3 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3433 PF11915.3 ETS85598.1 - 6.6e-18 64.6 4.6 6.6e-18 64.6 3.2 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) UPF0233 PF06781.7 ETS85598.1 - 0.66 9.6 4.3 0.33 10.6 0.2 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Ribonuc_L-PSP PF01042.16 ETS85600.1 - 8.5e-23 80.4 0.0 9.2e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SnoaL_2 PF12680.2 ETS85602.1 - 0.0043 17.4 0.3 0.01 16.1 0.1 1.6 1 1 1 2 2 2 1 SnoaL-like domain Pectate_lyase_3 PF12708.2 ETS85603.1 - 3.4e-78 262.8 15.5 3.8e-62 210.3 0.5 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein LysM PF01476.15 ETS85603.1 - 1.3e-10 41.0 1.9 0.00069 19.4 0.0 3.8 4 0 0 4 4 4 3 LysM domain End_N_terminal PF12218.3 ETS85603.1 - 5.1e-06 25.8 3.3 0.034 13.5 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.23 ETS85604.1 - 4.5e-75 253.2 0.3 6.9e-75 252.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS85604.1 - 2.6e-09 36.8 29.8 4.5e-08 32.9 4.8 5.9 6 0 0 6 6 6 2 Chitin recognition protein Esterase PF00756.15 ETS85607.1 - 7.3e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 ETS85607.1 - 0.00084 18.6 0.0 0.0034 16.6 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family CLAG PF03805.8 ETS85607.1 - 0.069 10.4 0.0 0.093 10.0 0.0 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Ank_2 PF12796.2 ETS85609.1 - 2.1e-56 188.2 0.6 7.4e-18 64.6 0.1 5.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85609.1 - 1.9e-48 159.9 1.9 5.1e-07 29.1 0.0 9.7 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 ETS85609.1 - 2.4e-41 138.8 4.6 1.3e-09 38.0 0.0 6.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) TPR_10 PF13374.1 ETS85609.1 - 1.8e-39 132.5 3.6 3.6e-06 26.7 0.0 9.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 ETS85609.1 - 2.1e-36 123.7 5.1 8.6e-10 38.4 0.5 5.6 3 1 3 6 6 6 5 Tetratricopeptide repeat Ank_4 PF13637.1 ETS85609.1 - 2.1e-34 117.2 0.5 1.3e-06 28.7 0.0 6.5 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85609.1 - 6.5e-34 112.5 0.9 3e-05 23.8 0.0 9.0 9 0 0 9 9 8 6 Ankyrin repeat Pkinase PF00069.20 ETS85609.1 - 7.3e-28 97.4 0.0 1.4e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85609.1 - 1.5e-16 60.2 0.0 2.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.1 ETS85609.1 - 2.6e-08 34.2 12.5 0.0018 18.8 0.2 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.9 ETS85609.1 - 6.2e-06 26.1 23.6 0.63 10.6 1.0 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS85609.1 - 2.4e-05 23.8 19.6 1.8 8.6 0.4 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS85609.1 - 4.3e-05 23.7 11.9 0.8 10.0 0.1 4.9 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS85609.1 - 7.5e-05 22.3 5.2 0.053 13.1 0.3 4.4 3 1 1 4 4 4 1 TPR repeat Apc3 PF12895.2 ETS85609.1 - 9.9e-05 22.4 3.0 0.5 10.5 0.0 4.0 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 ETS85609.1 - 0.0004 20.7 9.1 24 5.9 0.1 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85609.1 - 0.0015 18.1 12.0 2 8.4 0.0 6.2 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETS85609.1 - 0.024 14.7 7.1 31 4.7 0.0 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85609.1 - 0.2 11.3 14.8 11 5.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Pox_ser-thr_kin PF05445.6 ETS85609.1 - 0.38 9.4 0.0 0.59 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_3 PF07720.7 ETS85609.1 - 2.2 8.1 6.4 9.3 6.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat COesterase PF00135.23 ETS85610.1 - 7.5e-97 325.2 0.0 1e-96 324.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS85610.1 - 0.0036 16.8 0.1 0.0036 16.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold SKG6 PF08693.5 ETS85611.1 - 2.3 7.5 7.0 0.11 11.8 0.4 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_S10 PF00450.17 ETS85613.1 - 2.3e-78 264.2 0.0 3.1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 ETS85613.1 - 2.2e-11 44.0 0.0 7e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85613.1 - 2.5e-05 24.0 0.0 0.0004 20.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85613.1 - 0.012 15.1 0.1 0.075 12.5 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 ETS85613.1 - 0.015 15.2 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 TAP-like protein Act-Frag_cataly PF09192.5 ETS85613.1 - 0.051 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic PAN_4 PF14295.1 ETS85615.1 - 3.1e-06 26.7 17.8 0.0057 16.3 0.2 3.6 3 0 0 3 3 3 3 PAN domain MANEC PF07502.9 ETS85615.1 - 0.037 14.0 14.1 0.6 10.1 1.5 3.5 3 0 0 3 3 3 0 MANEC domain PAN_2 PF08276.6 ETS85615.1 - 0.16 11.8 10.8 3.6 7.4 0.1 3.5 3 0 0 3 3 3 0 PAN-like domain PAN_1 PF00024.21 ETS85615.1 - 0.25 11.1 8.1 6.3 6.6 0.8 3.7 3 0 0 3 3 3 0 PAN domain DAO PF01266.19 ETS85616.1 - 8.8e-56 189.3 0.1 1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS85616.1 - 6.3e-06 26.2 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85616.1 - 6.9e-06 26.0 0.0 2.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS85616.1 - 2e-05 24.3 0.1 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 ETS85616.1 - 0.00012 21.0 0.1 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS85616.1 - 0.00056 20.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS85616.1 - 0.0012 17.7 0.2 0.77 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 ETS85616.1 - 0.003 16.1 0.0 0.025 13.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS85616.1 - 0.0041 16.0 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 ETS85616.1 - 0.0051 17.1 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS85616.1 - 0.037 13.0 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS85617.1 - 3e-25 89.4 0.0 6.6e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85617.1 - 1.1e-16 60.1 0.0 2.6e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS85617.1 - 2.7e-11 43.3 0.3 1.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS85617.1 - 6.8e-09 35.0 0.0 3.9e-06 26.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS85617.1 - 0.00018 21.2 2.0 0.0089 15.8 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS85617.1 - 0.0021 17.9 0.0 0.024 14.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 ETS85617.1 - 0.0027 17.8 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 ETS85617.1 - 0.003 16.4 0.1 0.016 14.0 0.0 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS85617.1 - 0.0083 15.2 0.0 0.044 12.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 ETS85617.1 - 0.11 12.8 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 ETS85617.1 - 0.16 11.0 0.0 1.7 7.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Ring_hydroxyl_A PF00848.14 ETS85618.1 - 3.6e-37 128.0 5.6 3.1e-36 125.0 2.7 2.5 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 ETS85618.1 - 1.1e-12 47.3 0.0 2.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Cupin_1 PF00190.17 ETS85619.1 - 2.5e-08 33.4 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ETS85619.1 - 3.8e-07 29.5 0.1 6.7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 ETS85619.1 - 0.0045 16.6 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.9 ETS85619.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.14 ETS85619.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 ETS85619.1 - 0.051 12.9 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GPI PF06560.6 ETS85619.1 - 0.099 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ATG22 PF11700.3 ETS85620.1 - 4.1e-126 421.2 27.2 4.7e-126 421.0 18.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.4 ETS85620.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain IDO PF01231.13 ETS85621.1 - 9.9e-39 132.9 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Drf_FH3 PF06367.11 ETS85622.1 - 0.086 12.2 0.8 0.17 11.2 0.5 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain STAG PF08514.6 ETS85622.1 - 0.099 12.3 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 STAG domain DELLA PF12041.3 ETS85622.1 - 0.1 12.2 0.4 0.31 10.7 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Glyco_hydro_28 PF00295.12 ETS85625.1 - 7.7e-85 284.7 19.3 8.8e-85 284.5 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 ETS85625.1 - 0.00078 19.2 47.3 0.22 11.2 24.1 2.9 1 1 1 2 2 2 2 Right handed beta helix region SET PF00856.23 ETS85627.1 - 5.5e-09 36.5 0.0 5.5e-09 36.5 0.0 3.1 2 2 1 3 3 3 1 SET domain Ribosomal_L14 PF00238.14 ETS85628.1 - 1.3e-43 147.6 2.4 1.4e-43 147.5 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 ETS85629.1 - 5.9e-10 38.6 1.6 1.2e-09 37.6 1.1 1.6 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 ETS85629.1 - 0.085 12.8 4.3 0.85 9.5 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 ETS85629.1 - 0.13 12.0 2.9 0.26 11.1 2.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon Rotamase PF00639.16 ETS85630.1 - 3.1e-22 79.0 0.0 4.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 ETS85630.1 - 4.7e-17 62.3 0.0 5.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 ETS85630.1 - 5e-08 32.6 0.1 1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 ETS85630.1 - 1.8e-06 28.5 0.0 3.2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 ETS85630.1 - 0.061 13.1 0.2 0.37 10.5 0.0 1.9 1 1 1 2 2 2 0 MAM domain LrgB PF04172.11 ETS85631.1 - 8.9e-19 67.4 16.6 9e-13 47.8 1.8 3.2 3 1 0 3 3 3 2 LrgB-like family IL10 PF00726.12 ETS85632.1 - 0.092 12.0 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 Tropomyosin_1 PF12718.2 ETS85632.1 - 0.11 12.3 4.5 0.25 11.1 3.1 1.5 1 0 0 1 1 1 0 Tropomyosin like Mt_ATP-synt_B PF05405.9 ETS85632.1 - 0.13 11.6 1.9 1.9 7.9 0.3 2.5 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TPR_MLP1_2 PF07926.7 ETS85632.1 - 0.83 9.3 9.7 2.6 7.7 6.7 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 ETS85632.1 - 2.6 7.5 5.7 3.9 7.0 0.1 2.2 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 ETS85632.1 - 4.2 7.5 5.9 2.9 8.1 2.0 2.2 1 1 1 2 2 2 0 Syntaxin HalX PF08663.5 ETS85632.1 - 8.8 6.4 7.9 2.3 8.2 2.0 2.5 2 1 1 3 3 3 0 HalX domain DUF883 PF05957.8 ETS85632.1 - 8.8 6.8 9.8 2 8.8 2.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF769 PF05590.6 ETS85633.1 - 0.099 11.8 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) Amidoligase_2 PF12224.3 ETS85634.1 - 4.1e-10 39.7 0.1 2.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Putative amidoligase enzyme DUF1168 PF06658.7 ETS85635.1 - 0.031 13.8 14.7 0.04 13.4 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Activator_LAG-3 PF11498.3 ETS85635.1 - 0.062 12.0 39.8 0.073 11.8 27.6 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SOBP PF15279.1 ETS85635.1 - 0.22 11.8 8.3 0.23 11.8 5.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Suf PF05843.9 ETS85635.1 - 0.58 9.8 10.1 0.69 9.5 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.7 ETS85635.1 - 0.98 7.9 13.4 1.1 7.8 9.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Vfa1 PF08432.5 ETS85635.1 - 1.1 9.2 7.3 1.3 9.0 5.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PAT1 PF09770.4 ETS85635.1 - 1.4 7.0 23.2 1.7 6.8 16.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 ETS85635.1 - 3.6 7.1 14.3 4.3 6.9 9.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDHD PF02862.12 ETS85635.1 - 5.7 6.6 7.9 7 6.3 5.5 1.3 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 ETS85635.1 - 9.5 4.2 39.9 10 4.2 27.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 ETS85635.1 - 9.9 5.9 8.9 12 5.7 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.2 ETS85637.1 - 3.2e-16 59.4 2.7 3.9e-16 59.1 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85637.1 - 4.4e-15 54.6 3.1 8.7e-08 31.6 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS85637.1 - 3.6e-13 49.2 3.0 2.9e-07 30.5 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85637.1 - 4.7e-11 41.8 1.1 0.0012 18.9 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 ETS85637.1 - 8.3e-11 42.1 1.0 4.6e-07 30.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS85637.1 - 0.00019 21.4 4.1 0.0026 17.7 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 ETS85637.1 - 0.00032 20.4 0.2 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA PF00004.24 ETS85637.1 - 0.0037 17.4 0.2 1.1 9.4 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Peptidase_M3_N PF08439.5 ETS85637.1 - 0.044 13.8 2.5 0.1 12.6 0.8 2.3 2 0 0 2 2 2 0 Oligopeptidase F AAA_22 PF13401.1 ETS85637.1 - 0.046 13.8 0.0 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain HRDC PF00570.18 ETS85638.1 - 2.6e-22 78.3 0.0 7.3e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.15 ETS85638.1 - 6e-15 55.1 0.0 9e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.18 ETS85638.1 - 0.0028 17.2 0.2 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif FMN_dh PF01070.13 ETS85639.1 - 4.6e-82 275.7 0.7 1.9e-46 158.5 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS85639.1 - 2.1e-05 23.5 0.0 0.022 13.6 0.0 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase NMO PF03060.10 ETS85639.1 - 0.014 14.5 1.6 0.11 11.6 0.1 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase IMPDH PF00478.20 ETS85639.1 - 0.055 12.3 0.1 0.19 10.5 0.1 1.8 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain GMC_oxred_N PF00732.14 ETS85641.1 - 1.3e-56 191.9 0.0 1.7e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS85641.1 - 8e-28 97.5 0.2 1.5e-27 96.6 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS85641.1 - 0.0061 15.4 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS85641.1 - 0.015 14.2 0.4 0.35 9.7 0.3 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS85641.1 - 0.02 14.9 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85641.1 - 0.076 13.0 0.0 0.26 11.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_3_C PF01915.17 ETS85642.1 - 1.2e-38 132.8 0.0 2.1e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 ETS85642.1 - 6.3e-08 31.9 0.0 9.9e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 ETS85643.1 - 4.7e-07 29.6 0.0 8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain WSC PF01822.14 ETS85643.1 - 0.00027 20.7 2.7 0.0004 20.2 1.8 1.3 1 0 0 1 1 1 1 WSC domain CARDB PF07705.6 ETS85643.1 - 0.088 12.8 0.3 0.23 11.5 0.2 1.7 1 1 0 1 1 1 0 CARDB Sugar_tr PF00083.19 ETS85644.1 - 3.5e-93 312.6 25.5 4e-93 312.4 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85644.1 - 1.1e-34 119.7 44.4 1.1e-30 106.5 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS85644.1 - 3.7e-05 22.1 8.3 0.00065 18.0 2.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 ETS85644.1 - 0.0016 18.1 8.8 0.088 12.6 0.1 4.2 3 1 1 4 4 4 2 MFS_1 like family DUF3328 PF11807.3 ETS85646.1 - 7e-38 130.4 2.7 8.7e-38 130.1 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2970 PF11174.3 ETS85647.1 - 0.23 11.0 1.9 0.47 10.0 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF3328 PF11807.3 ETS85648.1 - 5.4e-43 147.1 0.7 1.2e-42 146.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) APH PF01636.18 ETS85648.1 - 3.7e-13 49.7 0.1 7.6e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS85648.1 - 0.00022 20.4 0.1 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pro-kuma_activ PF09286.6 ETS85649.1 - 8.6e-36 123.1 0.0 5.5e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS85649.1 - 1.3e-09 37.6 0.4 2.2e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Subtilase family MARVEL PF01284.18 ETS85651.1 - 3e-22 79.0 2.4 4.1e-22 78.5 1.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 ETS85651.1 - 0.1 11.8 6.4 0.42 9.8 1.9 2.2 2 0 0 2 2 2 0 Tetraspanin family Aldo_ket_red PF00248.16 ETS85652.1 - 4.6e-71 238.9 0.0 5.2e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 ETS85653.1 - 4.7e-13 48.6 0.1 7.8e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85653.1 - 1.5e-08 34.3 8.1 2.2e-08 33.8 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 ETS85655.1 - 3.9e-10 40.0 0.1 5.5e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 ETS85655.1 - 1e-07 31.4 0.6 1.5e-07 30.8 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 ETS85655.1 - 1.9e-07 30.3 0.2 3.2e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 ETS85655.1 - 4.3e-06 26.7 0.0 8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 ETS85655.1 - 2.5e-05 23.8 0.1 0.0071 15.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS85655.1 - 7.9e-05 21.7 0.1 0.014 14.2 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 ETS85655.1 - 0.00072 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS85655.1 - 0.0089 14.7 0.1 0.015 13.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.17 ETS85655.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 ETS85655.1 - 0.01 15.9 0.1 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 ETS85655.1 - 0.013 15.8 0.1 0.034 14.5 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 ETS85655.1 - 0.035 14.0 0.2 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase tRNA_U5-meth_tr PF05958.6 ETS85656.1 - 4.6e-10 38.7 0.0 6.7e-08 31.6 0.0 3.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 ETS85656.1 - 1.1e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 ETS85656.1 - 1.9e-07 30.7 0.0 4.9e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 ETS85656.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 ETS85656.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 ETS85656.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 ETS85656.1 - 0.00041 19.7 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS85656.1 - 0.0026 18.1 0.0 0.008 16.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS85656.1 - 0.0029 18.1 0.0 0.0073 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS85656.1 - 0.0052 17.2 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85656.1 - 0.0078 16.6 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain TRAM PF01938.15 ETS85656.1 - 0.011 15.4 2.2 0.014 15.1 0.2 2.1 3 0 0 3 3 3 0 TRAM domain UPF0020 PF01170.13 ETS85656.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 ETS85656.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase G_glu_transpept PF01019.16 ETS85657.1 - 1.1e-152 509.1 1.2 1.2e-152 508.9 0.8 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UNC45-central PF11701.3 ETS85658.1 - 8.4e-44 148.9 3.3 1.9e-41 141.3 0.0 4.1 5 1 0 5 5 5 2 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 ETS85658.1 - 0.034 13.8 0.4 1.8 8.3 0.0 3.1 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Tfb4 PF03850.9 ETS85659.1 - 1.8e-91 306.2 0.0 2.1e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 ETS85659.1 - 6.6e-05 23.0 0.3 0.00011 22.3 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 ETS85659.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Asparaginase_2 PF01112.13 ETS85660.1 - 3.5e-32 111.4 5.5 2.1e-19 69.4 0.0 2.5 3 0 0 3 3 3 2 Asparaginase Peptidase_M24 PF00557.19 ETS85660.1 - 0.023 14.2 0.4 0.51 9.8 0.1 2.3 2 0 0 2 2 2 0 Metallopeptidase family M24 Actin PF00022.14 ETS85661.1 - 1e-81 274.3 0.0 2.2e-81 273.2 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 ETS85661.1 - 0.017 13.7 0.1 0.96 7.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein F-box PF00646.28 ETS85662.1 - 0.00045 19.7 0.8 0.00099 18.6 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS85662.1 - 0.0034 17.0 0.7 0.0074 15.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 ETS85663.1 - 2.6e-23 82.2 0.5 5.8e-23 81.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85663.1 - 7.7e-06 25.7 9.6 1.4e-05 24.9 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 ETS85664.1 - 1.1e-16 60.8 2.1 1.4e-15 57.2 1.4 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS85664.1 - 0.011 15.6 2.3 0.029 14.3 1.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS85664.1 - 0.048 12.4 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.9 ETS85664.1 - 0.16 11.8 1.0 0.28 11.0 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS85664.1 - 0.34 9.7 4.6 0.56 9.0 1.6 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase Amidohydro_2 PF04909.9 ETS85665.1 - 4.8e-40 137.8 0.1 6e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase His_Phos_2 PF00328.17 ETS85666.1 - 0.00012 21.5 0.0 0.00054 19.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4305 PF14146.1 ETS85666.1 - 0.0031 17.2 2.1 0.0091 15.7 1.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4305) SKG6 PF08693.5 ETS85666.1 - 0.49 9.7 8.4 0.058 12.7 2.5 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Asp PF00026.18 ETS85667.1 - 7.2e-49 166.7 3.8 8.4e-49 166.5 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS85667.1 - 3.2e-05 23.9 0.1 6e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS85667.1 - 6.4e-05 23.3 0.0 0.25 11.8 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 ETS85667.1 - 0.0056 16.4 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 ETS85667.1 - 0.063 12.8 0.2 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal 2OG-FeII_Oxy PF03171.15 ETS85668.1 - 0.00033 20.8 0.1 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETS85668.1 - 0.0012 19.3 0.2 0.0029 18.0 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 ETS85669.1 - 1.1e-26 93.7 0.0 5.9e-23 81.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 ETS85669.1 - 1.4e-11 43.9 0.0 5.9e-10 38.7 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Glyco_hydro_61 PF03443.9 ETS85670.1 - 1.9e-66 223.9 1.2 2.2e-66 223.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rep_fac_C PF08542.6 ETS85671.1 - 4.1e-16 58.7 0.0 9.4e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 ETS85671.1 - 7.9e-16 58.4 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 ETS85671.1 - 3e-14 53.0 0.0 1.1e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 ETS85671.1 - 8.2e-09 34.6 0.0 6.3e-07 28.4 0.0 2.3 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 ETS85671.1 - 4.3e-07 30.1 0.0 2.2e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS85671.1 - 1.4e-06 27.9 0.0 3.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 ETS85671.1 - 3.7e-06 26.6 0.0 7.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS85671.1 - 3.8e-06 27.0 0.0 3.8e-05 23.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 ETS85671.1 - 5.3e-06 26.0 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 ETS85671.1 - 8.4e-06 24.7 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 ETS85671.1 - 1.8e-05 24.4 0.1 4.8e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 ETS85671.1 - 2.1e-05 24.2 0.1 0.00016 21.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS85671.1 - 2.6e-05 23.3 0.1 0.00023 20.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 ETS85671.1 - 3.6e-05 22.8 0.0 6.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 ETS85671.1 - 4.6e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 ETS85671.1 - 0.00016 21.3 0.1 0.00049 19.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 ETS85671.1 - 0.00031 20.2 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.11 ETS85671.1 - 0.00038 19.7 0.4 0.53 9.4 0.0 2.5 2 1 1 3 3 2 2 PhoH-like protein AAA_24 PF13479.1 ETS85671.1 - 0.00079 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETS85671.1 - 0.0013 17.9 0.1 0.0086 15.2 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 ETS85671.1 - 0.0044 16.0 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 ETS85671.1 - 0.0076 15.6 0.0 0.02 14.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS85671.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 ETS85671.1 - 0.014 14.8 0.1 3 7.1 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 ETS85671.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 ETS85671.1 - 0.018 14.5 0.0 0.41 10.1 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhageMin_Tail PF10145.4 ETS85671.1 - 0.019 14.5 0.1 0.055 13.1 0.1 1.7 1 0 0 1 1 1 0 Phage-related minor tail protein FtsK_SpoIIIE PF01580.13 ETS85671.1 - 0.03 13.8 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 ETS85671.1 - 0.03 13.7 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 ETS85671.1 - 0.035 14.9 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 ETS85671.1 - 0.049 13.4 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 ETS85671.1 - 0.052 12.3 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain Lon_2 PF13337.1 ETS85671.1 - 0.057 11.7 0.0 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease RNA_helicase PF00910.17 ETS85671.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RNA_pol_Rpc34 PF05158.7 ETS85671.1 - 0.078 12.1 0.0 0.22 10.6 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit Arch_ATPase PF01637.13 ETS85671.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase TK PF00265.13 ETS85671.1 - 0.099 12.2 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 1 0 Thymidine kinase COesterase PF00135.23 ETS85672.1 - 1.8e-91 307.4 0.1 2.2e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS85672.1 - 4.2e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS85672.1 - 4.7e-05 22.7 0.1 8.4e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS85672.1 - 0.0012 18.6 0.2 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DERM PF14704.1 ETS85672.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Dermatopontin MFS_1 PF07690.11 ETS85674.1 - 7.7e-11 41.2 61.1 3.2e-09 35.9 21.0 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.7 ETS85674.1 - 1 9.3 6.5 0.45 10.5 1.9 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-RING_3 PF14369.1 ETS85675.1 - 1.9 8.5 12.3 6.4 6.8 0.1 4.5 5 0 0 5 5 5 0 zinc-finger Histone PF00125.19 ETS85676.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 ETS85676.1 - 4.5e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Coprogen_oxidas PF01218.13 ETS85677.1 - 2e-122 407.3 0.1 2.3e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase R3H PF01424.17 ETS85678.1 - 3e-11 42.8 0.1 7.1e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 ETS85678.1 - 4.4e-07 29.7 0.0 8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS85678.1 - 2.9e-05 23.8 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS85678.1 - 0.00033 20.2 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FMO-like PF00743.14 ETS85679.1 - 3e-60 203.9 0.0 4.4e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS85679.1 - 9.5e-27 94.3 0.1 7e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85679.1 - 6.4e-11 42.5 0.0 1.3e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85679.1 - 2e-08 34.1 0.1 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS85679.1 - 3.5e-07 30.5 0.2 0.0031 17.8 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS85679.1 - 8.2e-07 28.9 1.6 0.00034 20.3 0.1 2.9 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 ETS85679.1 - 1e-06 27.9 2.6 0.00027 19.9 0.0 3.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 ETS85679.1 - 4.4e-06 25.8 0.0 1.5e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 ETS85679.1 - 5.2e-06 25.7 0.1 0.077 12.1 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS85679.1 - 3.2e-05 24.0 0.1 0.08 13.0 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 ETS85679.1 - 3.9e-05 23.2 0.1 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 ETS85679.1 - 4.6e-05 22.8 0.1 0.015 14.7 0.0 3.0 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 ETS85679.1 - 0.0002 20.5 0.4 0.38 9.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS85679.1 - 0.00045 19.6 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 ETS85679.1 - 0.0026 16.6 0.4 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 ETS85679.1 - 0.0032 17.7 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 ETS85679.1 - 0.0075 16.1 0.1 0.023 14.5 0.0 1.9 2 0 0 2 2 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.12 ETS85679.1 - 0.0075 15.3 0.1 0.25 10.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.16 ETS85679.1 - 0.0084 15.9 0.5 4.1 7.2 0.0 2.5 2 0 0 2 2 2 1 ThiF family ApbA PF02558.11 ETS85679.1 - 0.012 15.0 0.8 0.71 9.3 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 ETS85679.1 - 0.056 13.4 0.1 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 ETS85679.1 - 0.098 12.6 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 ETS85679.1 - 0.11 12.1 0.3 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tyrosinase PF00264.15 ETS85680.1 - 5.7e-36 124.7 3.3 7.8e-36 124.3 2.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase CoA_transf_3 PF02515.12 ETS85681.1 - 2.9e-27 95.1 0.4 7.3e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III 3HCDH_N PF02737.13 ETS85682.1 - 1e-47 162.1 0.0 1.4e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 ETS85682.1 - 7.6e-14 51.8 0.0 2.3e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 ETS85682.1 - 9.6e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 ETS85682.1 - 0.00041 19.7 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.1 ETS85682.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 ETS85682.1 - 0.0041 16.2 0.1 0.021 13.9 0.0 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS85682.1 - 0.0085 15.9 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 ETS85682.1 - 0.017 14.5 0.0 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 ETS85682.1 - 0.055 13.8 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_18 PF12847.2 ETS85682.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ldl_recept_b PF00058.12 ETS85683.1 - 7.7e-14 51.7 2.8 0.12 12.7 0.0 5.5 5 1 0 5 5 5 4 Low-density lipoprotein receptor repeat class B SGL PF08450.7 ETS85683.1 - 4.6e-06 26.2 0.5 0.32 10.3 0.1 3.3 1 1 0 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region Ribosomal_L13e PF01294.13 ETS85683.1 - 0.19 11.2 0.1 0.66 9.4 0.0 1.9 3 0 0 3 3 3 0 Ribosomal protein L13e polyprenyl_synt PF00348.12 ETS85684.1 - 2.8e-36 124.7 0.0 1e-35 122.8 0.0 1.8 2 0 0 2 2 2 1 Polyprenyl synthetase Pectinesterase PF01095.14 ETS85685.1 - 1e-54 185.1 10.5 1.3e-54 184.7 7.3 1.1 1 0 0 1 1 1 1 Pectinesterase Herpes_UL42 PF02282.11 ETS85685.1 - 0.024 14.2 0.1 0.065 12.8 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Phage_T4_Ndd PF06591.6 ETS85685.1 - 0.049 13.1 1.6 1.5 8.3 0.0 2.7 2 1 1 3 3 3 0 T4-like phage nuclear disruption protein (Ndd) zf-ZPR1 PF03367.8 ETS85686.1 - 3.1e-105 348.2 0.0 1.7e-53 180.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Rpr2 PF04032.11 ETS85687.1 - 4.7e-09 36.0 0.1 1.1e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-NADH-PPase PF09297.6 ETS85687.1 - 0.0041 16.5 2.2 0.041 13.3 0.3 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 ETS85687.1 - 0.008 15.8 0.7 1.9 8.2 0.1 2.3 2 0 0 2 2 2 2 Nudix N-terminal zf-ribbon_3 PF13248.1 ETS85687.1 - 0.034 13.3 0.3 7.6 5.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Herpes_UL49_1 PF03117.9 ETS85687.1 - 0.061 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 UL49 family A2L_zn_ribbon PF08792.5 ETS85687.1 - 0.066 12.6 0.5 9.6 5.8 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 ETS85687.1 - 0.12 11.7 0.3 17 4.8 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3133 PF11331.3 ETS85687.1 - 0.12 11.9 0.5 3.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) RRN7 PF11781.3 ETS85687.1 - 0.13 11.7 1.3 13 5.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1178 PF06676.6 ETS85687.1 - 1 9.5 3.8 0.78 9.9 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Peptidase_M4_C PF02868.10 ETS85688.1 - 1.9e-44 151.2 0.0 6.4e-44 149.5 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 ETS85688.1 - 7.2e-23 81.3 3.3 1.3e-22 80.5 2.3 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 ETS85688.1 - 0.044 12.9 0.2 0.089 11.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M13 Abhydrolase_6 PF12697.2 ETS85689.1 - 9e-24 84.6 0.9 2.2e-23 83.3 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85689.1 - 1e-15 57.7 0.0 2e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS85689.1 - 1.9e-06 27.6 0.0 5.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 ETS85689.1 - 0.00026 20.2 0.4 0.027 13.6 0.2 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 ETS85689.1 - 0.00055 19.5 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 ETS85689.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) UPF0227 PF05728.7 ETS85689.1 - 0.025 14.2 1.4 22 4.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 ETS85689.1 - 0.057 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 ETS85689.1 - 0.081 12.4 0.7 0.44 10.1 0.5 2.1 1 1 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 ETS85689.1 - 0.09 11.2 0.4 2.6 6.4 0.0 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) DUF1889 PF08986.5 ETS85689.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Ank_2 PF12796.2 ETS85690.1 - 2.2e-32 111.2 3.3 2.1e-11 43.9 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85690.1 - 8.9e-25 85.2 7.0 0.00048 19.7 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 ETS85690.1 - 9.7e-23 80.1 1.0 6.7e-06 26.4 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85690.1 - 1.2e-21 74.6 4.0 0.015 15.4 0.0 8.7 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 ETS85690.1 - 2.8e-21 75.0 1.0 2.3e-05 24.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) CorA PF01544.13 ETS85690.1 - 2.1e-11 43.3 0.0 4.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SUR7 PF06687.7 ETS85690.1 - 0.2 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family HeLo PF14479.1 ETS85692.1 - 6.8e-47 159.9 2.1 6.8e-47 159.9 1.4 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 ETS85692.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 ETS85692.1 - 0.063 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain 2-Hacid_dh_C PF02826.14 ETS85693.1 - 2.8e-44 150.4 0.0 4.1e-29 100.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 ETS85693.1 - 0.0084 16.0 0.9 0.085 12.8 0.1 2.3 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain EutN_CcmL PF03319.8 ETS85693.1 - 0.011 16.1 0.0 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome F420_oxidored PF03807.12 ETS85693.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 ETS85693.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 ETS85693.1 - 0.13 11.9 0.3 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dyp_perox PF04261.7 ETS85694.1 - 1.5e-89 299.8 0.0 1.9e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3328 PF11807.3 ETS85696.1 - 1.4e-51 175.2 3.0 1.7e-51 174.9 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RPE65 PF03055.10 ETS85697.1 - 2e-107 359.7 0.0 2.5e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SSP160 PF06933.6 ETS85698.1 - 0.21 9.5 5.2 0.27 9.1 3.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HET PF06985.6 ETS85699.1 - 1.3e-31 109.6 0.5 2.4e-31 108.7 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) L27 PF02828.11 ETS85701.1 - 0.1 12.3 2.2 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 L27 domain TPR_10 PF13374.1 ETS85702.1 - 5.8e-34 115.0 0.0 1.6e-11 43.7 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS85702.1 - 1.6e-26 91.9 0.0 2.8e-13 49.5 0.0 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 ETS85702.1 - 1.9e-06 26.9 0.1 6.1e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain TPR_7 PF13176.1 ETS85702.1 - 3e-06 26.5 0.9 0.89 9.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 ETS85702.1 - 2.1e-05 24.0 0.1 0.004 16.7 0.0 3.3 2 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.1 ETS85702.1 - 2.9e-05 23.9 0.0 1.2 9.5 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat NACHT PF05729.7 ETS85702.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 ETS85702.1 - 0.0049 16.6 0.6 5.1 7.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 ETS85702.1 - 0.0069 16.0 0.1 19 5.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85702.1 - 0.011 16.4 0.2 2.9 8.6 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85702.1 - 0.02 14.4 0.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS85702.1 - 0.061 13.6 1.7 19 5.6 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS85702.1 - 0.33 11.4 4.1 3.9 8.1 0.0 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 ETS85703.1 - 1.1e-44 150.6 3.4 1.9e-13 50.5 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85703.1 - 8.6e-35 116.8 2.2 6.4e-08 32.0 0.0 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 ETS85703.1 - 4.5e-30 102.9 3.4 3.4e-08 33.4 0.1 6.6 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS85703.1 - 4.2e-26 90.8 0.7 2.3e-06 27.9 0.0 6.9 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85703.1 - 5.5e-26 88.0 0.3 0.00044 20.2 0.0 9.1 10 0 0 10 10 10 5 Ankyrin repeat B2 PF11473.3 ETS85703.1 - 0.057 13.0 0.0 0.25 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA binding protein B2 Laminin_II PF06009.7 ETS85703.1 - 0.067 12.9 0.2 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Laminin Domain II Filament PF00038.16 ETS85703.1 - 0.23 10.9 1.4 0.44 9.9 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein PTR2 PF00854.16 ETS85704.1 - 3.1e-39 134.8 6.1 4.5e-39 134.3 4.3 1.2 1 0 0 1 1 1 1 POT family Pyr_redox_3 PF13738.1 ETS85705.1 - 1.4e-20 74.2 0.0 7.1e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85705.1 - 2e-13 49.4 0.0 4.4e-12 44.9 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS85705.1 - 2.5e-09 37.0 0.0 6.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS85705.1 - 3.8e-06 26.0 0.0 2.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS85705.1 - 0.00098 18.9 0.1 0.011 15.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Cupin_1 PF00190.17 ETS85706.1 - 0.0041 16.5 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 ETS85706.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Cupin_6 PF12852.2 ETS85706.1 - 0.062 12.9 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Glyco_transf_28 PF03033.15 ETS85707.1 - 3e-17 62.6 0.0 7.4e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS85707.1 - 1.3e-07 30.5 0.0 2.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 ETS85707.1 - 0.0015 18.6 0.1 0.0092 16.1 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 ETS85707.1 - 0.0045 16.6 1.4 0.0076 15.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Zn_clus PF00172.13 ETS85709.1 - 1.8e-09 37.3 10.0 3.7e-09 36.3 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS85709.1 - 0.0017 17.0 3.3 0.0019 16.9 1.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.23 ETS85710.1 - 4.2e-97 326.0 0.0 5.3e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS85710.1 - 2.2e-07 30.6 0.3 7.2e-07 28.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Tnp_DNA_bind PF14706.1 ETS85711.1 - 0.078 12.7 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Transposase DNA-binding AAA_13 PF13166.1 ETS85711.1 - 0.63 8.4 14.0 0.77 8.1 9.7 1.0 1 0 0 1 1 1 0 AAA domain XG_FTase PF03254.8 ETS85711.1 - 1 7.7 3.6 1.2 7.5 2.5 1.0 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase BTV_NS2 PF04514.7 ETS85711.1 - 3.8 6.3 11.2 3.9 6.2 7.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YEATS PF03366.11 ETS85712.1 - 3.6e-24 84.2 1.2 1e-22 79.6 0.8 2.2 1 1 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 ETS85713.1 - 3.3e-12 46.7 0.0 4.1e-11 43.2 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS85713.1 - 1.9e-07 30.7 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS85713.1 - 0.00016 20.4 0.0 0.00048 18.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS85713.1 - 0.0012 18.7 0.0 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETS85713.1 - 0.018 13.9 0.1 0.57 9.0 0.0 2.6 2 2 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 ETS85713.1 - 0.07 12.0 0.0 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain DUF2404 PF10296.4 ETS85714.1 - 6e-05 23.1 0.0 0.0002 21.4 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 ETS85715.1 - 1.1e-44 152.7 0.0 1.4e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.13 ETS85716.1 - 5.8e-37 127.5 6.6 5.8e-37 127.5 4.6 2.6 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 ETS85716.1 - 0.0061 15.3 2.0 0.0061 15.3 1.4 3.1 1 1 2 3 3 3 1 Major Facilitator Superfamily Pkinase PF00069.20 ETS85717.1 - 1.2e-70 237.7 0.9 3.7e-70 236.0 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85717.1 - 3.2e-53 180.4 0.2 5.9e-53 179.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 ETS85717.1 - 5e-22 78.0 1.1 9e-22 77.2 0.1 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 ETS85717.1 - 6.5e-08 31.8 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 ETS85717.1 - 7.7e-07 29.3 0.1 3.3e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 ETS85717.1 - 0.00031 20.5 2.0 0.0015 18.2 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS85717.1 - 0.095 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DDRGK PF09756.4 ETS85717.1 - 0.81 9.0 8.4 1.9 7.8 5.8 1.5 1 0 0 1 1 1 0 DDRGK domain tRNA-synt_2b PF00587.20 ETS85718.1 - 2.9e-68 228.8 0.0 9e-68 227.2 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS85718.1 - 2e-22 78.9 0.8 5.9e-22 77.4 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain Brix PF04427.13 ETS85719.1 - 2.3e-37 128.5 0.1 3.3e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 ETS85719.1 - 0.00012 20.1 22.6 0.00016 19.8 15.7 1.1 1 0 0 1 1 1 1 Nop14-like family Kinetochor_Ybp2 PF08568.5 ETS85720.1 - 1.6e-101 340.4 0.0 2.1e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SYF2 PF08231.7 ETS85721.1 - 1.8e-51 174.2 13.7 1.8e-51 174.2 9.5 2.1 2 0 0 2 2 2 1 SYF2 splicing factor ERCC4 PF02732.10 ETS85721.1 - 0.056 13.2 0.5 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 ERCC4 domain Rep_4 PF05797.6 ETS85721.1 - 0.79 8.3 9.2 0.12 11.0 3.2 1.8 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) OmpH PF03938.9 ETS85721.1 - 1.2 9.1 31.4 3.3 7.6 0.5 3.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Kelch_5 PF13854.1 ETS85723.1 - 3.4e-18 65.1 18.0 1.3e-11 44.2 1.3 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 ETS85723.1 - 2.4e-11 43.2 13.5 0.0001 22.0 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS85723.1 - 1.1e-06 28.5 18.0 0.05 13.8 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 ETS85723.1 - 0.0028 17.1 7.9 0.65 9.5 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 ETS85723.1 - 0.021 14.6 7.6 0.35 10.7 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Herpes_gE PF02480.11 ETS85723.1 - 0.098 10.9 0.3 0.14 10.3 0.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 ETS85723.1 - 0.28 10.9 1.7 0.41 10.4 0.4 1.8 2 0 0 2 2 2 0 DAP10 membrane protein Kelch_3 PF13415.1 ETS85723.1 - 3.6 7.8 19.9 3.1 8.0 0.1 5.5 8 0 0 8 8 8 0 Galactose oxidase, central domain HET PF06985.6 ETS85724.1 - 1.2e-35 122.7 0.1 1.7e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ecl1 PF12855.2 ETS85726.1 - 5.7e-13 47.9 1.3 9.5e-13 47.2 0.9 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 ETS85726.1 - 0.052 13.4 0.7 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 MYND finger DUF581 PF04570.9 ETS85726.1 - 0.09 12.0 3.8 0.23 10.7 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF581) C1_1 PF00130.17 ETS85726.1 - 0.16 11.7 2.6 0.26 11.0 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YL1 PF05764.8 ETS85727.1 - 3.6e-59 200.2 27.8 3.6e-59 200.2 19.3 3.3 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 ETS85727.1 - 8.5e-13 47.6 3.9 2.6e-12 46.0 0.9 2.4 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DUF2423 PF10338.4 ETS85728.1 - 6e-15 54.9 2.6 6e-15 54.9 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF3438 PF11920.3 ETS85728.1 - 0.031 13.1 1.3 0.037 12.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) HMG14_17 PF01101.13 ETS85728.1 - 0.35 11.6 12.0 0.16 12.6 6.7 1.7 1 1 0 1 1 1 0 HMG14 and HMG17 DUF4611 PF15387.1 ETS85728.1 - 0.99 9.5 7.3 2.1 8.5 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) SAP PF02037.22 ETS85729.1 - 4.9e-06 25.9 0.1 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 SAP domain PINIT PF14324.1 ETS85730.1 - 2e-39 134.9 0.0 3.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 ETS85730.1 - 4.5e-20 70.8 4.9 9.7e-20 69.8 3.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 ETS85730.1 - 4.2e-07 29.3 1.1 1.2e-06 27.9 0.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 ETS85730.1 - 0.21 11.4 1.1 0.51 10.1 0.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 ETS85730.1 - 0.28 10.9 3.7 0.63 9.8 2.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 ETS85730.1 - 0.34 10.7 4.8 0.62 9.9 3.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 ETS85730.1 - 1.8 8.4 5.8 3.2 7.6 4.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TRAPP PF04051.11 ETS85731.1 - 4.1e-45 153.0 0.0 4.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Secretin_N PF03958.12 ETS85731.1 - 1.1 9.4 4.3 2.5 8.3 3.0 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Ldh_1_N PF00056.18 ETS85732.1 - 1.3e-43 148.2 0.1 1.8e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 ETS85732.1 - 1.1e-42 145.7 0.0 1.6e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 ETS85732.1 - 0.0031 16.2 0.0 0.0052 15.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 ETS85732.1 - 0.095 12.0 0.2 8.5 5.6 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ribosomal_L28e PF01778.12 ETS85733.1 - 3.5e-40 137.0 1.3 4.4e-40 136.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 ETS85734.1 - 4.9e-46 155.6 0.0 5.4e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.8 ETS85735.1 - 1.6e-13 51.0 22.2 3.2e-13 50.0 12.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Tyrosinase PF00264.15 ETS85736.1 - 1.8e-46 159.0 0.8 2.9e-46 158.4 0.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase ABC_membrane PF00664.18 ETS85737.1 - 4.8e-85 285.3 33.9 6.3e-45 153.7 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS85737.1 - 2.8e-70 234.9 0.0 3.5e-35 121.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS85737.1 - 3.6e-16 59.0 1.1 9.5e-05 21.7 0.0 4.8 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS85737.1 - 6.1e-13 49.3 0.3 0.0049 16.8 0.0 4.7 5 0 0 5 5 5 3 AAA domain AAA_16 PF13191.1 ETS85737.1 - 2.3e-11 44.0 2.7 9.6e-06 25.7 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 ETS85737.1 - 4.5e-09 35.4 0.4 0.00066 18.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 ETS85737.1 - 2.6e-08 33.2 0.0 0.00089 18.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS85737.1 - 7.8e-08 33.1 0.0 0.014 16.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 ETS85737.1 - 1.4e-07 30.8 0.3 0.0052 16.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS85737.1 - 4.4e-07 30.0 1.3 0.016 15.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 ETS85737.1 - 5.8e-06 26.1 1.6 0.17 11.8 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 ETS85737.1 - 0.00013 21.6 3.3 0.3 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 ETS85737.1 - 0.00029 20.3 0.4 0.64 9.3 0.1 3.6 3 1 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 ETS85737.1 - 0.00076 19.8 0.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS85737.1 - 0.00091 19.5 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS85737.1 - 0.0012 18.6 0.0 0.76 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS85737.1 - 0.0018 18.4 0.1 9.8 6.3 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 ETS85737.1 - 0.0029 16.7 0.1 2.3 7.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 ETS85737.1 - 0.0036 17.2 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 ETS85737.1 - 0.0049 16.8 1.0 6.4 6.7 0.1 3.6 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 ETS85737.1 - 0.011 15.4 0.1 3.9 7.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 ETS85737.1 - 0.012 15.0 2.6 1.4 8.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 ETS85737.1 - 0.015 15.1 0.0 6.2 6.7 0.0 3.3 3 1 1 4 4 3 0 AAA domain DUF87 PF01935.12 ETS85737.1 - 0.017 14.9 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 ETS85737.1 - 0.038 12.6 0.1 6.3 5.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.9 ETS85737.1 - 0.052 13.2 0.1 6.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 ETS85737.1 - 0.063 12.7 0.0 13 5.1 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 ETS85737.1 - 0.067 12.7 0.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 ETS85737.1 - 0.068 13.3 0.1 9.7 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 ETS85737.1 - 0.14 10.8 0.0 0.3 9.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_15 PF13175.1 ETS85737.1 - 0.18 10.8 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF3328 PF11807.3 ETS85739.1 - 9.6e-49 165.9 0.1 1.2e-48 165.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRAP_alpha PF03896.11 ETS85740.1 - 2 7.3 5.5 2.8 6.8 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.3 ETS85740.1 - 8.9 6.1 11.6 12 5.7 8.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Selenoprotein_S PF06936.6 ETS85740.1 - 9.1 5.7 7.0 4.3 6.8 1.5 2.2 1 1 1 2 2 2 0 Selenoprotein S (SelS) WD40 PF00400.27 ETS85741.1 - 1.2e-70 231.0 15.1 5.8e-11 41.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 ETS85741.1 - 6.4e-21 74.3 9.6 9.9e-21 73.7 6.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 ETS85741.1 - 0.0038 15.4 2.3 0.47 8.5 0.0 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 ETS85741.1 - 0.0051 15.6 0.1 0.72 8.5 0.1 3.4 1 1 3 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETS85741.1 - 0.02 13.1 0.4 0.6 8.3 0.1 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain LXG PF04740.7 ETS85741.1 - 0.035 13.8 1.2 0.052 13.3 0.9 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nbas_N PF15492.1 ETS85741.1 - 0.063 12.3 0.1 16 4.5 0.0 3.0 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF4604 PF15377.1 ETS85742.1 - 5.5 7.1 17.4 1.5 8.9 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Adeno_E3B PF03376.9 ETS85743.1 - 1.1 9.2 7.1 0.21 11.5 0.9 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein HET PF06985.6 ETS85745.1 - 1.9e-18 66.9 1.0 7.5e-18 65.0 0.7 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tim17 PF02466.14 ETS85748.1 - 6.7e-26 90.8 2.9 8.6e-26 90.4 2.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 ETS85748.1 - 0.27 10.5 2.6 0.54 9.5 1.8 1.4 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DUF2428 PF10350.4 ETS85749.1 - 8.1e-70 234.7 1.0 2.8e-69 232.9 0.7 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 ETS85749.1 - 3.8e-06 26.5 11.4 1.3 9.3 0.1 7.1 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 ETS85749.1 - 0.0014 18.8 5.4 0.062 13.5 0.2 5.1 5 1 0 5 5 5 1 HEAT repeats ApoLp-III PF07464.6 ETS85749.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3074 PF11274.3 ETS85750.1 - 3.1e-56 189.9 3.6 4.1e-54 183.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) TPR_MLP1_2 PF07926.7 ETS85750.1 - 0.64 9.7 39.2 0.085 12.5 22.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WSC PF01822.14 ETS85751.1 - 1.6e-18 66.3 8.6 3.8e-18 65.1 5.9 1.6 1 0 0 1 1 1 1 WSC domain Fungal_lectin PF07938.7 ETS85752.1 - 7.6e-08 31.9 0.3 0.00091 18.6 0.0 2.1 1 1 1 2 2 2 2 Fungal fucose-specific lectin DUF2158 PF09926.4 ETS85752.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Steroid_dh PF02544.11 ETS85753.1 - 2.4e-14 53.3 0.2 2.4e-14 53.3 0.2 1.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 ETS85753.1 - 0.0025 17.1 0.1 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) SUFU PF05076.8 ETS85753.1 - 0.13 11.7 0.1 14 5.2 0.0 2.2 1 1 1 2 2 2 0 Suppressor of fused protein (SUFU) 2OG-FeII_Oxy_2 PF13532.1 ETS85754.1 - 2.3e-13 50.4 0.0 5.4e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 ETS85754.1 - 9.9e-06 25.7 0.0 1.9e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 ETS85755.1 - 4.4e-26 91.0 0.8 1.2e-15 57.5 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85755.1 - 6.2e-18 63.6 4.8 5.1e-08 32.3 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETS85755.1 - 1.1e-14 54.0 2.4 2.7e-05 24.2 0.2 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS85755.1 - 4.5e-14 52.4 0.0 0.00061 20.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85755.1 - 6e-11 41.4 0.0 0.0028 17.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat TGS PF02824.16 ETS85756.1 - 8.9e-20 70.2 0.0 1.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 ETS85756.1 - 7.1e-18 64.6 0.0 2.5e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS85756.1 - 1.9e-09 36.9 0.0 1e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 ETS85756.1 - 1.9e-05 24.1 0.1 0.3 10.4 0.0 3.5 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 ETS85756.1 - 0.00013 21.8 0.1 0.032 14.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 ETS85756.1 - 0.0077 15.0 0.3 0.024 13.3 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 ETS85756.1 - 0.011 16.2 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 ETS85756.1 - 0.05 12.8 0.1 8.3 5.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 ETS85757.1 - 2.9e-11 43.0 0.1 9.4e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 ETS85757.1 - 6.4e-07 28.6 2.0 1e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 ETS85757.1 - 0.0038 16.8 0.0 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 MarR family Tocopherol_cycl PF14249.1 ETS85757.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Tocopherol cyclase HTH_Tnp_IS630 PF01710.11 ETS85757.1 - 0.17 11.5 0.2 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Transposase PXA PF02194.10 ETS85758.1 - 4e-39 134.1 0.6 7.9e-39 133.1 0.2 1.6 2 0 0 2 2 2 1 PXA domain zf-Mss51 PF13824.1 ETS85759.1 - 4.6e-27 93.6 7.2 4.6e-27 93.6 5.0 2.0 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 ETS85759.1 - 0.0026 17.5 1.8 0.0026 17.5 1.2 2.1 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 ETS85759.1 - 0.028 14.3 0.9 0.075 12.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CPSF_A PF03178.10 ETS85760.1 - 1.3e-100 336.6 0.0 7.9e-100 334.0 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 ETS85760.1 - 9.4e-68 228.5 0.0 1.6e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 ETS85760.1 - 0.057 13.3 0.2 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat UBA_4 PF14555.1 ETS85761.1 - 0.0033 16.9 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 ETS85761.1 - 0.0041 16.9 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain GRAM PF02893.15 ETS85762.1 - 0.00046 19.6 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Myosin_TH1 PF06017.8 ETS85762.1 - 0.037 13.3 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Myosin tail MgtE PF01769.11 ETS85762.1 - 0.12 12.6 0.6 0.27 11.5 0.4 1.5 1 0 0 1 1 1 0 Divalent cation transporter Glyco_hydro_6 PF01341.12 ETS85763.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Peptidase_M4_C PF02868.10 ETS85764.1 - 2.4e-20 72.9 0.6 3.9e-20 72.2 0.4 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 ETS85764.1 - 8.5e-19 68.1 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 ETS85764.1 - 0.0021 17.2 0.2 0.0065 15.6 0.1 1.8 1 1 1 2 2 2 1 Peptidase family M13 Abhydrolase_3 PF07859.8 ETS85765.1 - 2.3e-45 154.7 0.0 6.5e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS85765.1 - 0.025 13.3 1.5 0.15 10.6 1.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family DUF3025 PF11227.3 ETS85765.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) LRR_4 PF12799.2 ETS85766.1 - 5.8e-16 57.7 4.3 8.8e-05 22.0 2.2 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS85766.1 - 3.2e-12 46.0 18.5 5.1e-07 29.3 2.3 3.4 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 ETS85766.1 - 1.4e-09 36.6 5.5 0.84 9.9 0.0 6.4 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 ETS85766.1 - 0.00017 21.2 9.2 15 6.3 0.2 6.1 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 ETS85766.1 - 0.00046 19.9 3.9 15 6.0 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat ATP-synt_DE_N PF02823.11 ETS85768.1 - 2.9e-20 71.8 0.1 4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.4 ETS85769.1 - 1.5e-142 475.6 26.1 1.5e-142 475.6 18.1 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 ETS85769.1 - 7.3 5.5 10.5 14 4.5 7.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Arf PF00025.16 ETS85770.1 - 2.8e-66 222.0 0.0 3.2e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 ETS85770.1 - 1.5e-10 40.3 0.1 6.3e-07 28.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 ETS85770.1 - 1.4e-08 35.2 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 ETS85770.1 - 7.5e-08 31.8 0.0 9.5e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 ETS85770.1 - 9.2e-08 31.6 0.0 1.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETS85770.1 - 2.2e-07 30.8 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 ETS85770.1 - 6.4e-06 25.4 0.0 7.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 ETS85770.1 - 0.00038 19.9 0.0 0.019 14.3 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 ETS85770.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3336 PF11815.3 ETS85771.1 - 4.4e-49 165.7 6.5 7e-49 165.0 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 ETS85771.1 - 1.5e-19 70.7 0.1 5.1e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Dioxygenase_C PF00775.16 ETS85772.1 - 5.2e-09 35.6 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 ETS85773.1 - 7.2e-49 166.9 0.5 1e-48 166.4 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-HC5HC2H_2 PF13832.1 ETS85774.1 - 8.7e-35 119.0 6.6 8.7e-35 119.0 4.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS85774.1 - 5.6e-27 93.7 6.3 5.6e-27 93.7 4.3 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 ETS85774.1 - 2e-17 63.9 1.3 2e-17 63.9 0.9 2.6 3 1 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 ETS85774.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 ETS85774.1 - 5.9e-09 35.4 24.4 8.9e-08 31.7 6.7 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 ETS85774.1 - 1 9.4 22.4 0.017 15.0 4.1 2.8 2 0 0 2 2 2 0 RING-like domain Metallophos PF00149.23 ETS85775.1 - 6.7e-45 152.9 0.2 8.1e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rdx PF10262.4 ETS85776.1 - 7e-30 102.8 0.0 1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family K_channel_TID PF07941.6 ETS85776.1 - 0.12 12.6 7.0 0.55 10.4 0.7 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain G-gamma PF00631.17 ETS85777.1 - 1e-26 92.4 0.0 1.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 GGL domain Pheromone PF08015.6 ETS85777.1 - 4.9 8.0 6.7 7 7.5 4.1 1.7 2 0 0 2 2 2 0 Fungal mating-type pheromone PCI PF01399.22 ETS85778.1 - 4.2e-07 30.2 0.0 4.2e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 PCI domain WSC PF01822.14 ETS85780.1 - 4.6e-31 106.5 25.2 1.7e-17 63.0 5.7 5.7 4 1 1 5 5 5 2 WSC domain Glyco_tranf_2_3 PF13641.1 ETS85781.1 - 1.2e-20 74.3 0.0 2e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 ETS85781.1 - 1.6e-09 37.7 0.6 1.6e-09 37.7 0.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 ETS85781.1 - 7.1e-06 25.4 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 ETS85781.1 - 5.5e-05 22.9 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 WAP PF00095.16 ETS85782.1 - 2.6 8.1 6.3 3.6 7.6 0.1 2.6 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CoA_transf_3 PF02515.12 ETS85783.1 - 6.7e-27 93.9 0.0 1.4e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.13 ETS85784.1 - 3.7e-23 81.7 0.0 7.3e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Biotin_lipoyl PF00364.17 ETS85785.1 - 2.2e-20 72.0 0.7 4e-20 71.2 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 ETS85785.1 - 1.5e-06 27.7 0.0 4.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 ETS85785.1 - 3.1e-05 23.5 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 ETS85785.1 - 0.18 10.9 0.1 1.4 7.9 0.0 2.0 1 1 0 1 1 1 0 HlyD family secretion protein Sulfotransfer_3 PF13469.1 ETS85787.1 - 9e-05 23.4 0.0 0.00014 22.7 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Nucleoporin_FG PF13634.1 ETS85788.1 - 0.01 16.0 2.5 0.027 14.6 1.8 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region MAD PF05557.8 ETS85788.1 - 0.2 9.7 0.3 0.28 9.2 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HET PF06985.6 ETS85789.1 - 1.4e-22 80.3 0.0 3.2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS85790.1 - 1.6e-30 105.2 0.0 6.9e-07 29.5 0.0 6.1 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS85790.1 - 3.4e-24 84.7 0.0 3.6e-06 27.3 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS85790.1 - 7.3e-22 76.9 0.0 9.2e-05 22.5 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 ETS85790.1 - 1.6e-20 71.7 4.3 2.4e-05 23.9 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Pkinase PF00069.20 ETS85790.1 - 1.2e-17 63.9 0.0 2.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 ETS85790.1 - 1.1e-16 59.2 3.5 0.00049 20.0 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Pkinase_Tyr PF07714.12 ETS85790.1 - 3.3e-10 39.4 0.0 5.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC37_C PF08564.5 ETS85790.1 - 0.041 13.7 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Cdc37 C terminal domain HeLo PF14479.1 ETS85791.1 - 6.3e-09 35.8 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation GMC_oxred_C PF05199.8 ETS85792.1 - 3.3e-22 79.3 0.1 3.8e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 ETS85793.1 - 5.1e-08 32.0 3.2 5.9e-08 31.8 2.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85793.1 - 0.0012 17.4 1.7 0.0025 16.4 1.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85794.1 - 2.3e-10 39.7 20.5 2.6e-10 39.5 14.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Cutinase PF01083.17 ETS85795.1 - 3.1e-33 114.9 5.1 3.8e-33 114.7 3.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS85795.1 - 0.022 14.2 0.1 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 ETS85795.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 ETS85796.1 - 7.3e-22 77.5 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 ETS85796.1 - 0.00013 21.9 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85796.1 - 0.00021 21.0 0.1 0.00026 20.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.7 ETS85796.1 - 0.00072 18.5 0.0 0.00093 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PAF-AH_p_II PF03403.8 ETS85796.1 - 0.0022 16.3 0.0 0.0031 15.8 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 ETS85796.1 - 0.0027 17.1 0.2 0.005 16.2 0.1 1.4 1 1 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 ETS85796.1 - 0.014 14.7 0.1 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 ETS85796.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein GMC_oxred_N PF00732.14 ETS85797.1 - 1.8e-60 204.5 0.0 2.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS85797.1 - 3.3e-32 111.7 0.0 6.6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS85797.1 - 2e-06 26.9 0.1 0.005 15.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS85797.1 - 0.00014 20.9 0.1 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS85797.1 - 0.00086 18.2 0.5 0.85 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 ETS85797.1 - 0.015 15.2 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85797.1 - 0.02 14.9 0.1 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS85797.1 - 0.049 12.2 0.2 0.077 11.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 ETS85797.1 - 0.13 12.7 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS85797.1 - 0.17 10.9 0.3 0.34 9.9 0.1 1.5 2 0 0 2 2 2 0 Thi4 family p450 PF00067.17 ETS85798.1 - 2.7e-39 135.0 0.0 5.1e-38 130.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS85799.1 - 1.8e-27 96.1 0.1 3.7e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS85800.1 - 3.2e-33 114.8 0.3 5.4e-33 114.0 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.3 ETS85801.1 - 1.9e-35 121.1 0.6 3.6e-35 120.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) KR PF08659.5 ETS85802.1 - 5e-35 120.8 0.1 7.2e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS85802.1 - 2.2e-24 86.2 0.0 3.7e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DIT1_PvcA PF05141.7 ETS85803.1 - 0.027 13.7 0.4 0.027 13.7 0.2 2.0 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Phage-Gp8 PF09215.5 ETS85804.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 AAA PF00004.24 ETS85805.1 - 1.4e-19 70.6 0.0 3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS85805.1 - 3.2e-05 24.0 0.4 0.077 13.1 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS85805.1 - 0.00011 21.8 0.0 0.00037 20.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 ETS85805.1 - 0.00028 20.8 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS85805.1 - 0.0009 19.2 0.0 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS85805.1 - 0.0014 18.3 0.0 0.0043 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS85805.1 - 0.0017 19.1 0.0 0.0055 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS85805.1 - 0.0019 17.8 0.4 0.011 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 ETS85805.1 - 0.005 16.7 0.3 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS85806.1 - 4.7e-33 114.3 0.0 1.4e-32 112.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 ETS85806.1 - 1.1e-23 84.0 10.4 2.8e-23 82.7 7.2 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 ETS85806.1 - 2.1e-06 27.1 0.2 3.8e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS85806.1 - 2.6e-05 24.3 0.0 0.035 14.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS85806.1 - 0.0044 16.5 0.1 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 ETS85806.1 - 0.0061 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 ETS85806.1 - 0.007 15.3 0.2 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SbcCD_C PF13558.1 ETS85806.1 - 0.014 15.2 0.1 0.17 11.8 0.1 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 ETS85806.1 - 0.033 14.1 0.1 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 ETS85806.1 - 0.035 14.2 0.0 0.57 10.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS85806.1 - 0.22 11.6 0.8 2 8.5 0.6 2.3 1 1 0 1 1 1 0 AAA domain TRAM_LAG1_CLN8 PF03798.11 ETS85808.1 - 8.9e-35 120.0 20.4 1.8e-34 119.0 14.1 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 ETS85808.1 - 1.2e-24 85.5 0.3 2.9e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein PalH PF08733.5 ETS85809.1 - 6.5e-107 357.3 0.0 8.1e-107 357.0 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.1 ETS85809.1 - 0.015 15.2 5.6 1.4 8.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) AAA PF00004.24 ETS85811.1 - 1.2e-98 326.3 0.0 8.2e-48 161.9 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 ETS85811.1 - 2e-20 72.5 1.1 5.9e-20 71.0 0.3 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 ETS85811.1 - 8.3e-14 51.8 0.0 2.6e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 ETS85811.1 - 1.1e-13 50.7 0.0 6.6e-06 25.3 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 ETS85811.1 - 7.2e-13 48.4 1.5 9.3e-07 28.6 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 ETS85811.1 - 7.5e-13 48.5 0.0 1e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 ETS85811.1 - 4.9e-12 46.1 0.4 0.00068 19.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS85811.1 - 1.8e-11 44.3 0.0 0.00037 20.5 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 ETS85811.1 - 3.1e-11 44.1 0.0 0.00028 21.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 ETS85811.1 - 2e-09 36.6 0.6 0.00087 18.1 0.0 3.1 3 0 0 3 3 3 2 TIP49 C-terminus AAA_25 PF13481.1 ETS85811.1 - 1.6e-08 34.2 5.7 0.013 14.8 0.0 4.6 3 2 2 5 5 4 3 AAA domain AAA_14 PF13173.1 ETS85811.1 - 1.7e-08 34.3 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 ETS85811.1 - 3e-08 33.2 1.6 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 ETS85811.1 - 3.3e-08 33.1 0.0 0.0053 16.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 ETS85811.1 - 8.9e-08 31.4 0.0 0.008 15.2 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin CDC48_2 PF02933.12 ETS85811.1 - 9.3e-08 31.6 0.0 2.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 ETS85811.1 - 1.7e-07 30.6 0.2 0.0056 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETS85811.1 - 5.3e-07 29.7 0.0 0.029 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 ETS85811.1 - 6.6e-07 28.6 0.7 0.23 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 ETS85811.1 - 7.6e-07 28.2 0.0 0.0037 16.2 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 ETS85811.1 - 1.5e-06 28.5 0.0 0.086 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 ETS85811.1 - 1.9e-06 27.8 0.0 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 ETS85811.1 - 2.1e-06 27.4 0.2 0.094 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 ETS85811.1 - 3.6e-06 27.0 0.0 0.085 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 ETS85811.1 - 7.5e-06 25.0 0.1 0.043 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 ETS85811.1 - 8.4e-06 25.6 0.0 4.9 6.7 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 ETS85811.1 - 1e-05 25.6 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 ETS85811.1 - 1.5e-05 24.5 0.0 0.17 11.3 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 ETS85811.1 - 1.5e-05 24.7 0.1 0.084 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 ETS85811.1 - 2.4e-05 24.6 0.0 0.22 11.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 ETS85811.1 - 6.1e-05 22.7 0.0 0.41 10.2 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein PhoH PF02562.11 ETS85811.1 - 0.00013 21.2 0.2 0.49 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 ETS85811.1 - 0.00016 21.2 0.0 0.58 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 ETS85811.1 - 0.00019 21.1 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 ETS85811.1 - 0.0005 19.7 0.0 0.79 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 ETS85811.1 - 0.00069 19.4 0.1 0.0068 16.2 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 ETS85811.1 - 0.00081 18.3 0.0 0.55 9.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.10 ETS85811.1 - 0.00092 18.9 0.2 0.64 9.7 0.0 3.8 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 ETS85811.1 - 0.0016 17.4 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 ETS85811.1 - 0.0061 16.1 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 ETS85811.1 - 0.01 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 ETS85811.1 - 0.013 14.5 0.5 1.4 7.8 0.0 3.4 2 2 1 4 4 4 0 KAP family P-loop domain UPF0079 PF02367.12 ETS85811.1 - 0.017 14.7 0.1 8.8 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 ETS85811.1 - 0.017 14.6 0.1 15 4.9 0.1 4.1 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 ETS85811.1 - 0.029 13.8 0.5 1.5 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 ETS85811.1 - 0.038 12.8 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.11 ETS85811.1 - 0.064 12.0 0.0 7.8 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 ETS85811.1 - 0.098 12.5 0.1 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 ETS85811.1 - 0.13 11.4 0.5 11 5.1 0.0 2.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 ETS85811.1 - 0.14 11.8 1.1 3.4 7.3 0.0 3.3 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B UFD1 PF03152.9 ETS85811.1 - 0.16 11.1 0.0 10 5.1 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AAA_23 PF13476.1 ETS85811.1 - 0.18 12.1 1.5 4.4 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain ASF1_hist_chap PF04729.8 ETS85812.1 - 3.8e-67 224.7 0.0 5e-67 224.3 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.9 ETS85813.1 - 1.4e-78 264.4 6.7 2e-73 247.5 0.0 3.6 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 ETS85813.1 - 4.3e-05 23.7 1.6 1.6 9.5 0.0 6.2 5 1 2 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.5 ETS85813.1 - 0.0046 15.8 0.2 0.0046 15.8 0.1 3.5 3 1 1 4 4 4 1 NRDE-2, necessary for RNA interference FemAB PF02388.11 ETS85813.1 - 0.0087 14.7 1.7 0.014 14.1 0.1 1.8 2 0 0 2 2 2 1 FemAB family TPR_19 PF14559.1 ETS85813.1 - 0.013 15.8 0.0 0.16 12.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3467 PF11950.3 ETS85813.1 - 0.047 13.7 0.2 0.29 11.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3467) BUD22 PF09073.5 ETS85813.1 - 1.3 8.0 6.4 0.87 8.5 1.6 2.1 2 0 0 2 2 2 0 BUD22 Piwi PF02171.12 ETS85814.1 - 3.2e-71 239.7 1.7 3.6e-71 239.6 0.2 1.7 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 ETS85814.1 - 9.4e-12 44.1 0.0 3e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 ETS85814.1 - 8e-10 38.1 0.1 1.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 PAZ domain RGS PF00615.14 ETS85815.1 - 0.00012 22.1 0.0 0.00065 19.7 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2415 PF10313.4 ETS85817.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) DUF2353 PF09789.4 ETS85818.1 - 0.034 13.3 9.9 0.74 9.0 2.1 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF342 PF03961.8 ETS85818.1 - 0.88 7.9 3.5 1 7.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 ETS85818.1 - 1.6 7.8 7.1 2.2 7.4 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 ETS85818.1 - 6.8 6.2 14.6 9 5.8 10.1 1.2 1 0 0 1 1 1 0 IncA protein NEL PF14496.1 ETS85820.1 - 0.061 12.5 0.1 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting DUF455 PF04305.9 ETS85821.1 - 2.6e-101 338.1 0.0 3.3e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 ETS85821.1 - 3.9e-06 26.3 0.0 7.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 ETS85821.1 - 0.00036 20.2 0.0 0.0013 18.3 0.0 2.0 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain AMMECR1 PF01871.12 ETS85822.1 - 3e-47 159.9 0.0 1.2e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 Asp PF00026.18 ETS85823.1 - 9.7e-61 205.7 6.6 9.7e-61 205.7 4.6 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Ras PF00071.17 ETS85824.1 - 7e-39 132.8 0.0 3.2e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 ETS85824.1 - 5.9e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS85824.1 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 ETS85824.1 - 0.0098 15.1 0.0 0.039 13.1 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family PRK PF00485.13 ETS85824.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.22 ETS85824.1 - 0.025 14.0 0.0 0.67 9.3 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain adh_short PF00106.20 ETS85825.1 - 3.8e-32 111.5 0.2 5e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85825.1 - 5e-19 69.0 0.0 6.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85825.1 - 1.8e-12 47.2 0.1 2.6e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS85825.1 - 1.1e-09 38.5 0.1 1.6e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS85825.1 - 5.4e-05 22.4 0.0 6.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 ETS85825.1 - 0.00025 20.5 0.0 0.00083 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 ETS85825.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Eno-Rase_NADH_b PF12242.3 ETS85825.1 - 0.012 15.3 1.5 0.036 13.8 0.0 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 ETS85825.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 ETS85825.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 ETS85825.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Ank_2 PF12796.2 ETS85826.1 - 8.1e-67 221.6 1.3 2.1e-23 82.4 0.3 6.4 3 2 2 6 6 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85826.1 - 7.1e-55 180.1 16.0 1.1e-08 34.4 0.1 12.0 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 ETS85826.1 - 2.2e-47 158.6 18.5 2.3e-10 40.7 0.1 8.7 3 2 6 10 10 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85826.1 - 1.6e-46 151.6 6.1 2.1e-06 27.3 0.0 12.4 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.1 ETS85826.1 - 1.3e-40 136.4 15.1 2.3e-06 27.6 0.0 9.0 4 2 6 10 10 10 9 Ankyrin repeats (many copies) NACHT PF05729.7 ETS85826.1 - 2.3e-11 43.6 0.0 8.8e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS85826.1 - 6.7e-05 23.0 0.0 0.00026 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS85826.1 - 0.0002 21.3 0.0 0.0013 18.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 ETS85826.1 - 0.0039 16.1 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2420 PF10336.4 ETS85826.1 - 0.01 15.4 0.0 0.058 12.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) AAA_33 PF13671.1 ETS85826.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS85826.1 - 0.035 14.2 0.3 0.17 12.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 ETS85826.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin adh_short PF00106.20 ETS85827.1 - 2.2e-21 76.4 0.8 4.2e-21 75.5 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85827.1 - 1.6e-13 51.0 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85827.1 - 1e-05 25.2 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS85827.1 - 4.4e-05 22.7 0.0 5.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 ETS85827.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase APH PF01636.18 ETS85828.1 - 8.6e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS85828.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1264 PF06884.6 ETS85829.1 - 2.3e-73 245.2 0.2 2.7e-73 244.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF2347 PF09804.4 ETS85830.1 - 3.1e-106 354.7 0.0 9e-106 353.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 ETS85830.1 - 8e-44 149.8 0.0 1.8e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 ETS85830.1 - 1e-05 25.1 0.0 5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 ETS85830.1 - 0.012 14.1 0.0 0.54 8.6 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 Zn_clus PF00172.13 ETS85831.1 - 0.00099 18.9 2.0 0.0015 18.3 1.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 ETS85832.1 - 9.9e-08 31.7 19.5 0.00025 20.8 3.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec63 PF02889.11 ETS85833.1 - 4.9e-44 150.8 0.0 1.5e-43 149.2 0.0 1.7 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 ETS85833.1 - 6.6e-17 61.0 2.0 1.6e-16 59.8 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_3 PF00933.16 ETS85834.1 - 1.4e-68 231.0 0.0 2.2e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS85834.1 - 4.8e-55 186.5 0.0 7.5e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS85834.1 - 2.1e-15 56.4 0.0 5.2e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS85834.1 - 8.1e-09 35.2 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Amino_oxidase PF01593.19 ETS85835.1 - 1.7e-31 109.8 0.0 7.8e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS85835.1 - 3.9e-08 33.2 0.0 1.3e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS85835.1 - 0.032 13.1 1.3 0.14 11.0 0.1 2.5 2 2 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS85835.1 - 0.17 10.9 0.0 0.46 9.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 ETS85836.1 - 3.3e-38 131.5 0.0 4.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS85836.1 - 4.3e-09 35.7 0.2 2e-06 26.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS85836.1 - 2e-06 27.7 0.2 5.6e-06 26.2 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS85836.1 - 4.9e-06 25.7 0.0 8.7e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 ETS85836.1 - 2.6e-05 22.8 0.1 4.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 ETS85836.1 - 0.0001 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 ETS85836.1 - 0.00018 20.4 0.1 0.0035 16.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 ETS85836.1 - 0.00023 20.3 0.1 0.00039 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS85836.1 - 0.0003 21.1 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS85836.1 - 0.00035 20.5 0.1 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS85836.1 - 0.00045 20.3 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS85836.1 - 0.0091 14.9 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 ETS85836.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.1 ETS85836.1 - 0.022 13.7 0.1 2 7.2 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GDI PF00996.13 ETS85836.1 - 0.046 12.0 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.11 ETS85836.1 - 0.076 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 ETS85836.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SMI1_KNR4 PF09346.5 ETS85836.1 - 0.077 13.0 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) UDPG_MGDP_dh_N PF03721.9 ETS85836.1 - 0.12 11.7 0.6 1.5 8.1 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.11 ETS85837.1 - 4.4e-16 58.5 33.6 4.4e-16 58.5 23.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily CheC PF04509.7 ETS85837.1 - 0.15 11.8 0.9 8.5 6.2 0.1 2.4 2 0 0 2 2 2 0 CheC-like family NmrA PF05368.8 ETS85838.1 - 1.1e-33 116.4 0.0 1.4e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS85838.1 - 4.1e-24 85.5 0.8 4.1e-24 85.5 0.6 1.5 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS85838.1 - 4.3e-06 25.8 0.0 5.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETS85838.1 - 0.0067 15.1 0.1 0.0095 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS85838.1 - 0.0084 16.0 0.6 0.0084 16.0 0.4 2.3 2 1 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.13 ETS85838.1 - 0.016 15.2 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 ETS85838.1 - 0.043 14.2 0.5 0.37 11.2 0.0 2.5 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 ETS85838.1 - 0.12 11.7 0.2 0.27 10.6 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS85838.1 - 0.19 11.3 1.8 0.29 10.7 0.6 1.8 2 1 0 2 2 2 0 KR domain Aa_trans PF01490.13 ETS85839.1 - 2.9e-16 58.9 12.5 4.1e-16 58.4 8.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2633 PF11119.3 ETS85839.1 - 0.2 11.3 2.7 0.88 9.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF4131 PF13567.1 ETS85839.1 - 4.2 6.7 14.4 0.6 9.4 0.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M20 PF01546.23 ETS85840.1 - 1e-20 74.0 1.8 1.8e-20 73.2 1.3 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS85840.1 - 2.3e-20 72.4 0.1 4.1e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS85840.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PQ-loop PF04193.9 ETS85841.1 - 2e-37 126.5 6.4 2.1e-18 65.6 0.2 2.8 2 1 0 2 2 2 2 PQ loop repeat ATG22 PF11700.3 ETS85841.1 - 0.0014 17.1 0.0 0.0034 15.9 0.0 1.7 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like ABC2_membrane_3 PF12698.2 ETS85841.1 - 0.029 13.4 0.3 0.068 12.1 0.2 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2530 PF10745.4 ETS85841.1 - 0.66 9.9 4.4 11 6.1 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) DUF1282 PF06930.7 ETS85841.1 - 2.3 7.8 8.2 1.7 8.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) DUF3328 PF11807.3 ETS85843.1 - 1.5e-47 162.1 6.3 1.9e-47 161.7 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.1 ETS85844.1 - 9.5e-29 100.3 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.23 ETS85845.1 - 9e-06 26.0 0.2 0.00057 20.2 0.2 2.3 1 1 0 1 1 1 1 SET domain DUF1828 PF08861.5 ETS85845.1 - 0.021 14.4 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1828 SAF PF08666.7 ETS85845.1 - 0.089 13.2 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 SAF domain DUF4606 PF15379.1 ETS85845.1 - 0.092 12.8 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Peptidase_S10 PF00450.17 ETS85846.1 - 1.8e-30 106.4 0.1 3.2e-19 69.3 0.0 3.0 2 1 0 2 2 2 2 Serine carboxypeptidase Transketolase_N PF00456.16 ETS85847.1 - 1.2e-136 454.9 0.0 1.6e-136 454.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS85847.1 - 1.6e-34 118.9 0.0 3.6e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 ETS85847.1 - 7.2e-12 45.3 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 ETS85847.1 - 0.00048 19.7 0.6 0.0019 17.7 0.4 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 ETS85847.1 - 0.0013 17.4 0.0 0.0022 16.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Med10 PF09748.4 ETS85850.1 - 4.9e-39 133.0 0.0 5.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Flagellin_N PF00669.15 ETS85850.1 - 0.025 14.3 1.5 0.046 13.5 1.1 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region CPL PF08144.6 ETS85850.1 - 0.091 12.5 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 CPL (NUC119) domain PAM2 PF07145.10 ETS85851.1 - 0.0095 15.3 0.1 0.023 14.1 0.1 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region HET PF06985.6 ETS85852.1 - 1.9e-24 86.3 0.0 3.4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 ETS85853.1 - 1.3e-13 50.5 4.3 2.8e-13 49.5 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS85853.1 - 1.5e-11 43.9 0.1 3.8e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Ank_2 PF12796.2 ETS85854.1 - 1.6e-11 44.3 0.3 1.6e-06 28.3 0.1 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85854.1 - 4.7e-08 32.4 4.2 1.4 8.8 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 ETS85854.1 - 4.3e-07 30.2 0.4 0.47 11.0 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS85854.1 - 6e-07 29.0 2.8 11 6.5 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 ETS85854.1 - 4.3e-06 26.7 3.9 0.9 9.8 0.0 4.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) NAD_binding_10 PF13460.1 ETS85856.1 - 5.8e-12 45.9 0.3 2.4e-11 43.9 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS85856.1 - 1.9e-11 43.8 0.1 2e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 ETS85856.1 - 1.9e-05 24.0 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 ETS85856.1 - 0.00012 20.9 0.0 0.00016 20.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS85856.1 - 0.00015 21.7 0.2 0.00036 20.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 ETS85856.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 ETS85856.1 - 0.011 14.6 0.6 0.062 12.2 0.4 2.2 1 1 0 1 1 1 0 Male sterility protein adh_short_C2 PF13561.1 ETS85856.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3816 PF12822.2 ETS85857.1 - 0.85 9.4 9.2 1.3 8.8 5.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF1049 PF06305.6 ETS85857.1 - 0.88 9.0 2.9 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Pyr_redox_3 PF13738.1 ETS85858.1 - 2.8e-24 86.3 0.0 5.9e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85858.1 - 4.6e-16 58.1 0.3 3.4e-14 51.9 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS85858.1 - 1.7e-12 47.1 0.0 6.2e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS85858.1 - 1.1e-10 40.9 0.0 4.5e-08 32.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 ETS85858.1 - 1.8e-05 23.8 0.0 0.0074 15.2 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS85858.1 - 2.5e-05 24.0 0.0 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 1 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 ETS85858.1 - 0.0057 16.7 0.0 0.15 12.1 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 ETS85858.1 - 0.0068 16.3 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS85858.1 - 0.031 12.7 0.0 0.059 11.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 ETS85858.1 - 0.044 12.8 0.0 1.3 7.9 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 ETS85858.1 - 0.047 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GARS_N PF02844.10 ETS85858.1 - 0.049 14.1 0.0 3.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Pyr_redox PF00070.22 ETS85858.1 - 0.085 13.2 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.3 ETS85859.1 - 1.5e-88 297.4 0.0 1.8e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 ETS85860.1 - 2.9e-61 207.4 0.0 3.6e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 ETS85861.1 - 8.5e-12 45.4 7.4 4e-11 43.2 5.1 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1489 PF07370.6 ETS85861.1 - 0.0084 15.6 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1489) APH PF01636.18 ETS85862.1 - 9.7e-13 48.4 0.0 3.9e-11 43.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS85862.1 - 9.2e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 ETS85862.1 - 0.019 13.6 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 ETS85862.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family GMC_oxred_N PF00732.14 ETS85863.1 - 4.1e-64 216.5 0.0 5.7e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS85863.1 - 6.5e-30 104.3 0.0 2.1e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS85863.1 - 4.5e-05 22.5 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 ETS85863.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS85863.1 - 0.021 13.7 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 ETS85863.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 ETS85863.1 - 0.024 13.7 0.5 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 ETS85863.1 - 0.024 13.2 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 ETS85863.1 - 0.06 13.2 0.1 0.36 10.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 ETS85864.1 - 1.6e-18 66.5 0.8 2.6e-18 65.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85864.1 - 7.5e-05 22.5 11.1 0.00013 21.7 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LcrV PF04792.7 ETS85864.1 - 0.064 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein CN_hydrolase PF00795.17 ETS85865.1 - 7.8e-22 77.5 0.0 1.7e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.15 ETS85866.1 - 7.4e-49 167.1 1.5 9.4e-49 166.8 1.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS85866.1 - 7.2e-18 65.5 2.1 8.1e-17 62.1 0.4 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS85866.1 - 4.4e-17 62.3 2.4 1.1e-14 54.4 0.2 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS85866.1 - 4e-11 42.5 0.0 1.1e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 ETS85866.1 - 6.5e-05 22.0 0.1 0.00017 20.6 0.1 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase DisA_N PF02457.11 ETS85866.1 - 0.024 13.7 0.4 0.19 10.8 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding DAO PF01266.19 ETS85867.1 - 3.3e-18 65.7 0.2 6.3e-18 64.8 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS85867.1 - 0.031 14.1 2.8 0.051 13.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85867.1 - 0.04 13.9 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS85867.1 - 0.052 12.4 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amidohydro_4 PF13147.1 ETS85868.1 - 3.4e-24 86.3 0.2 5.3e-24 85.7 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS85868.1 - 3.1e-10 39.8 0.0 9.2e-10 38.2 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 ETS85868.1 - 4.5e-10 39.6 0.3 1.9e-08 34.3 0.2 2.4 1 1 0 1 1 1 1 Amidohydrolase family DIOX_N PF14226.1 ETS85869.1 - 1.1e-28 100.1 0.0 2.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS85869.1 - 2.1e-17 63.2 0.0 9e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ORF6N PF10543.4 ETS85869.1 - 0.077 13.0 0.5 0.15 12.1 0.4 1.4 1 0 0 1 1 1 0 ORF6N domain DIOX_N PF14226.1 ETS85870.1 - 1.2e-29 103.2 0.0 1.9e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS85870.1 - 7.3e-20 71.1 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 ETS85871.1 - 8.7e-32 110.1 19.0 8.7e-32 110.1 13.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4500 PF14937.1 ETS85871.1 - 0.18 11.6 2.5 9.9 6.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) ADH_zinc_N PF00107.21 ETS85872.1 - 3e-21 75.3 1.2 5.8e-21 74.3 0.3 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS85872.1 - 5.2e-21 74.4 0.2 8.7e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.9 ETS85872.1 - 0.049 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GXWXG PF14231.1 ETS85873.1 - 8.4e-23 79.7 0.1 1.2e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 GXWXG protein DUF4334 PF14232.1 ETS85873.1 - 1.7e-21 75.6 0.7 5.3e-21 74.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) Corona_NS2 PF04753.7 ETS85873.1 - 0.0044 16.9 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Coronavirus non-structural protein NS2 DUF2249 PF10006.4 ETS85873.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) DUF3425 PF11905.3 ETS85874.1 - 4.2e-25 88.2 0.2 7.7e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) GST_C PF00043.20 ETS85876.1 - 2.9e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS85876.1 - 6.6e-06 26.2 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS85876.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS85876.1 - 0.002 17.9 0.0 0.0046 16.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS85876.1 - 0.015 15.7 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glucan_synthase PF02364.10 ETS85877.1 - 0.063 11.1 0.6 0.07 10.9 0.4 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component ORC4_C PF14629.1 ETS85877.1 - 0.083 12.2 0.2 0.091 12.1 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Macoilin PF09726.4 ETS85877.1 - 2 6.6 7.1 2.4 6.3 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 ETS85878.1 - 0.77 10.0 6.0 0.89 9.8 4.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 ETS85878.1 - 0.86 8.9 11.3 1.2 8.4 7.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PP-binding PF00550.20 ETS85879.1 - 4.3e-11 42.9 0.2 5.9e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 ETS85879.1 - 1.4e-05 25.0 0.2 1.8e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.22 ETS85880.1 - 1.2e-13 49.9 16.5 4.9e-08 32.2 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 ETS85880.1 - 4.4e-12 46.1 10.5 7.2e-12 45.5 7.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 ETS85880.1 - 1.3e-09 38.1 11.1 2.5e-09 37.2 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 ETS85880.1 - 1.4e-09 38.5 7.2 0.00016 22.3 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 ETS85880.1 - 5.1e-09 35.7 11.5 1.3e-08 34.4 8.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 ETS85880.1 - 5.9e-08 32.6 20.4 1.5e-05 24.9 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.1 ETS85880.1 - 8.4e-08 31.9 10.9 0.00032 20.5 1.5 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 ETS85880.1 - 1.1e-07 31.3 14.7 0.0004 20.1 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 ETS85880.1 - 2.1e-07 30.4 17.1 0.0011 18.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 ETS85880.1 - 9.8e-07 29.0 7.8 0.0003 21.0 7.2 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 ETS85880.1 - 2.2e-06 27.5 11.8 0.0003 20.8 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 ETS85880.1 - 2.7e-05 24.5 9.6 0.011 16.1 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 ETS85880.1 - 0.0076 16.6 15.2 0.28 11.6 3.2 2.8 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 ETS85880.1 - 0.017 15.6 13.3 0.24 11.9 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 ETS85880.1 - 0.049 13.7 4.6 0.061 13.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 ETS85880.1 - 0.061 13.9 16.9 0.15 12.7 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Cellulase PF00150.13 ETS85881.1 - 3.9e-08 32.8 0.1 9.6e-08 31.5 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 ETS85883.1 - 4.3e-31 107.9 24.6 4.3e-31 107.9 17.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85883.1 - 3.5e-12 45.6 7.2 3.5e-12 45.6 5.0 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 ETS85883.1 - 0.0046 15.2 4.2 0.0084 14.3 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.3 ETS85883.1 - 0.56 9.3 8.2 0.25 10.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Glyco_hydro_3 PF00933.16 ETS85884.1 - 6e-85 284.8 0.0 8.7e-85 284.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS85884.1 - 7.6e-53 179.3 0.0 1.2e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS85884.1 - 1.8e-23 82.2 0.0 3.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TraW_N PF12477.3 ETS85884.1 - 0.081 12.8 0.4 0.081 12.8 0.2 2.4 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Peptidase_M28 PF04389.12 ETS85885.1 - 4.2e-22 78.7 0.0 7.9e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 ETS85885.1 - 3.6e-06 26.6 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cnl2_NKP2 PF09447.5 ETS85885.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein FAA_hydrolase PF01557.13 ETS85886.1 - 5.7e-53 179.5 0.0 7.5e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 ETS85887.1 - 7.3e-20 70.9 0.2 1.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 ETS85888.1 - 8.3e-20 71.1 0.0 3.2e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS85888.1 - 1.5e-09 37.2 1.9 0.00022 20.2 1.9 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS85888.1 - 2.6e-05 23.2 1.8 4e-05 22.6 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS85888.1 - 3.7e-05 24.0 0.0 0.00096 19.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85888.1 - 0.00011 22.1 1.1 0.00033 20.6 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS85888.1 - 0.00023 19.7 0.8 0.00038 19.0 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 ETS85888.1 - 0.001 17.9 0.0 0.01 14.6 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 ETS85888.1 - 0.0021 17.0 1.0 0.003 16.4 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 ETS85888.1 - 0.0024 16.9 1.0 0.0037 16.3 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS85888.1 - 0.0078 16.1 0.4 0.017 15.0 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS85888.1 - 0.0088 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 ETS85888.1 - 0.013 14.6 0.2 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 ETS85888.1 - 0.053 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Abhydrolase_3 PF07859.8 ETS85889.1 - 1.8e-15 57.1 0.0 8.4e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS85889.1 - 7.7e-12 44.8 0.0 9e-09 34.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS85889.1 - 5.2e-10 39.2 0.0 9.3e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS85889.1 - 5.2e-08 33.0 0.1 7.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 ETS85889.1 - 1.8e-07 30.8 0.5 0.00092 18.7 0.0 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 ETS85889.1 - 0.00015 20.6 0.1 0.00042 19.1 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family LIP PF03583.9 ETS85889.1 - 0.02 14.0 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.15 ETS85889.1 - 0.051 12.9 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 ETS85889.1 - 0.059 12.7 0.0 13 5.0 0.0 2.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.2 ETS85889.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Cupin_2 PF07883.6 ETS85890.1 - 2.3e-12 46.2 0.5 2.1e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 ETS85890.1 - 0.0083 15.4 0.2 0.77 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS85890.1 - 0.02 14.5 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.7 ETS85890.1 - 0.11 11.7 0.4 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein DUF1255 PF06865.6 ETS85890.1 - 0.14 12.3 0.0 0.89 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1255) TPR_11 PF13414.1 ETS85891.1 - 4e-09 35.9 13.7 1.4e-05 24.5 0.3 4.5 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.1 ETS85891.1 - 4.7e-07 29.6 9.4 0.02 14.8 0.4 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS85891.1 - 1.9e-06 28.1 10.1 0.002 18.4 0.1 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS85891.1 - 4.3e-06 26.2 26.6 0.00027 20.6 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS85891.1 - 3.7e-05 23.1 19.0 0.00051 19.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85891.1 - 7.6e-05 23.2 13.6 1.5 9.5 0.6 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85891.1 - 0.00074 19.9 16.0 0.95 10.2 0.1 6.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85891.1 - 0.00082 18.9 6.2 0.56 10.1 0.1 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS85891.1 - 0.0011 18.5 12.0 0.33 10.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS85891.1 - 0.024 14.8 2.4 47 4.5 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 ETS85891.1 - 0.2 11.5 2.2 6.6 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 ETS85891.1 - 3.8 8.2 8.5 15 6.3 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TauD PF02668.11 ETS85892.1 - 1.3e-35 123.2 0.2 2e-35 122.7 0.2 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family dCMP_cyt_deam_1 PF00383.17 ETS85893.1 - 5.8e-09 35.5 0.1 1.1e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 ETS85893.1 - 0.049 13.4 2.0 0.17 11.7 1.4 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase PA14_2 PF10528.4 ETS85894.1 - 2.4e-17 62.9 1.0 5.5e-17 61.7 0.7 1.6 1 0 0 1 1 1 1 GLEYA domain Peptidase_S9 PF00326.16 ETS85895.1 - 2.5e-12 46.4 0.1 5.1e-12 45.4 0.0 1.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS85895.1 - 3e-07 30.3 0.3 3.8e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS85895.1 - 1.3e-05 24.8 0.2 2.4e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 ETS85895.1 - 0.00056 19.2 0.0 0.001 18.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.4 ETS85895.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_2 PF02230.11 ETS85895.1 - 0.058 12.8 0.0 8.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2424 PF10340.4 ETS85895.1 - 0.14 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) RHIM PF12721.2 ETS85895.1 - 1.1 9.7 3.6 1.1 9.6 0.5 2.5 3 0 0 3 3 3 0 RIP homotypic interaction motif DIOX_N PF14226.1 ETS85896.1 - 2.5e-19 69.9 0.0 5.7e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS85896.1 - 1.1e-17 64.1 0.0 7.2e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.18 ETS85897.1 - 2.8e-29 101.3 1.2 4.7e-29 100.6 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS85897.1 - 0.018 14.9 0.7 0.06 13.2 0.1 2.1 2 0 0 2 2 2 0 Berberine and berberine like DsbC_N PF10411.4 ETS85897.1 - 0.1 11.8 0.5 0.58 9.4 0.0 2.3 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus Transp_cyt_pur PF02133.10 ETS85899.1 - 6.2e-91 305.1 36.8 7.4e-91 304.8 25.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 ETS85900.1 - 1.9e-06 26.9 2.4 3.6e-06 26.0 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Packaging_FI PF14000.1 ETS85900.1 - 0.043 14.0 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 DNA packaging protein FI Abhydrolase_6 PF12697.2 ETS85901.1 - 1.1e-36 126.8 0.8 1.3e-36 126.5 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS85901.1 - 5.6e-21 74.8 0.2 3.4e-20 72.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS85901.1 - 1.3e-16 60.8 0.0 4.7e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS85901.1 - 2.6e-09 37.6 0.0 7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 ETS85901.1 - 7.3e-09 35.4 0.2 3e-06 26.9 0.1 2.3 1 1 1 2 2 2 2 Serine hydrolase Ndr PF03096.9 ETS85901.1 - 2.2e-07 29.6 0.0 2.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 ETS85901.1 - 3.6e-05 23.3 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 ETS85901.1 - 5.9e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 ETS85901.1 - 9.6e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 ETS85901.1 - 0.003 17.1 0.1 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 ETS85901.1 - 0.0038 16.6 0.2 0.026 13.9 0.1 2.0 1 1 0 1 1 1 1 Putative esterase DUF1749 PF08538.5 ETS85901.1 - 0.004 16.1 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 ETS85901.1 - 0.0041 16.6 0.0 0.35 10.2 0.0 2.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF2305 PF10230.4 ETS85901.1 - 0.0047 16.3 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 ETS85901.1 - 0.0049 15.8 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 ETS85901.1 - 0.01 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.8 ETS85901.1 - 0.016 13.5 0.2 1.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 ETS85901.1 - 0.046 12.9 0.0 0.16 11.2 0.0 2.0 2 1 1 3 3 3 0 Dienelactone hydrolase family DUF3530 PF12048.3 ETS85901.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF900 PF05990.7 ETS85901.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 ETS85901.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein TauD PF02668.11 ETS85902.1 - 1.1e-36 126.8 0.4 1.7e-36 126.2 0.3 1.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Barwin PF00967.12 ETS85903.1 - 0.00043 19.9 0.3 0.00052 19.6 0.2 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 ETS85903.1 - 0.017 15.0 0.1 0.055 13.4 0.1 1.8 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel HET PF06985.6 ETS85904.1 - 1.3e-32 112.8 0.3 2.1e-32 112.1 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clusterin PF01093.12 ETS85904.1 - 0.0013 17.5 0.1 0.035 12.9 0.0 2.1 2 0 0 2 2 2 2 Clusterin Transp_cyt_pur PF02133.10 ETS85905.1 - 1.7e-90 303.7 38.7 2e-90 303.5 26.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 ETS85906.1 - 2.3e-109 365.2 0.4 3.4e-109 364.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 ETS85906.1 - 1.1e-51 175.6 9.3 3.6e-50 170.7 4.2 3.2 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 ETS85906.1 - 5.8e-34 117.1 2.7 1.2e-30 106.3 0.0 3.7 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 ETS85906.1 - 4.8e-05 22.4 0.5 0.14 11.0 0.0 2.7 2 1 1 3 3 3 2 StbA protein BcrAD_BadFG PF01869.15 ETS85906.1 - 0.0002 20.7 0.1 0.0002 20.7 0.1 3.7 4 1 0 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 ETS85906.1 - 0.0016 16.8 0.4 0.017 13.4 0.0 2.5 2 0 0 2 2 2 1 MutL protein Pyr_redox_3 PF13738.1 ETS85907.1 - 2.1e-25 90.0 0.0 4.6e-23 82.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS85907.1 - 7.3e-15 54.1 0.0 6.6e-13 47.7 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS85907.1 - 9e-14 51.1 0.0 4.1e-11 42.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS85907.1 - 1.5e-09 38.0 0.0 2.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85907.1 - 5.1e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS85907.1 - 8.6e-06 25.6 0.0 0.00055 19.7 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 ETS85907.1 - 9.5e-05 21.4 0.0 0.011 14.6 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 ETS85907.1 - 0.0016 16.9 0.0 0.45 8.9 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 ETS85907.1 - 0.0022 17.1 0.0 0.0059 15.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETS85907.1 - 0.0073 16.6 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS85907.1 - 0.012 14.5 0.1 0.45 9.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS85907.1 - 0.028 13.2 0.1 0.05 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.10 ETS85907.1 - 0.21 9.7 0.0 7.2 4.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) adh_short_C2 PF13561.1 ETS85908.1 - 5e-30 105.0 0.0 6.1e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS85908.1 - 1.6e-27 96.5 0.1 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85908.1 - 3.7e-17 62.5 0.0 5.7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 ETS85908.1 - 0.0011 17.7 0.1 0.0021 16.8 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS85908.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3132 PF11330.3 ETS85908.1 - 0.095 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) adh_short PF00106.20 ETS85909.1 - 2.7e-26 92.4 5.4 1.7e-25 89.8 3.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS85909.1 - 5.6e-26 91.7 0.1 7e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS85909.1 - 9.4e-12 44.9 2.0 3.8e-11 42.9 1.4 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85909.1 - 0.00029 20.3 1.2 0.0024 17.3 0.8 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS85909.1 - 0.0035 16.3 0.0 0.0066 15.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS85909.1 - 0.028 14.5 0.1 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CAP PF00188.21 ETS85910.1 - 1.8e-18 67.2 5.3 2.4e-18 66.8 3.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.27 ETS85911.1 - 1.4e-11 43.8 10.3 0.0013 18.5 0.2 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat PPR_2 PF13041.1 ETS85912.1 - 0.00064 19.6 0.0 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 PPR repeat family MFS_1 PF07690.11 ETS85914.1 - 1.7e-46 158.5 29.5 1.7e-46 158.5 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85914.1 - 6.8e-11 41.4 10.1 6.8e-11 41.4 7.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 ETS85914.1 - 0.00019 19.9 1.7 0.00019 19.9 1.2 3.8 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 ETS85914.1 - 0.00021 19.5 1.7 0.00021 19.5 1.2 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector UPF0233 PF06781.7 ETS85914.1 - 0.13 11.8 1.7 1.5 8.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Transp_cyt_pur PF02133.10 ETS85915.1 - 1.8e-36 125.6 37.1 1.7e-35 122.4 25.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HET PF06985.6 ETS85916.1 - 1.1e-20 74.2 0.0 3e-20 72.7 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KR PF08659.5 ETS85917.1 - 3.6e-54 183.1 0.1 8.5e-54 181.9 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS85917.1 - 8.4e-40 136.4 0.2 8.4e-40 136.4 0.2 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 ETS85917.1 - 5.1e-15 55.1 0.0 1.4e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS85917.1 - 4.7e-08 32.7 1.2 1e-07 31.6 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS85917.1 - 5e-08 33.8 0.0 4.2e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 ETS85917.1 - 0.023 14.9 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Phosphopantetheine attachment site PTCB-BRCT PF12738.2 ETS85917.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain DUF1380 PF07128.7 ETS85917.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Gcd10p PF04189.8 ETS85917.1 - 0.25 10.4 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Gcd10p family Isochorismatase PF00857.15 ETS85918.1 - 1.7e-26 93.1 0.0 2.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4148 PF13663.1 ETS85918.1 - 0.04 13.7 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF3292 PF11696.3 ETS85919.1 - 9.5e-246 816.6 0.0 1.1e-245 816.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 ETS85919.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal PMI_typeI PF01238.16 ETS85920.1 - 2.4e-71 240.6 0.1 3.1e-70 237.0 0.1 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 ETS85920.1 - 2.7e-06 26.7 0.6 0.0011 18.4 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 ETS85920.1 - 0.0044 16.7 0.1 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 ETS85920.1 - 0.012 14.9 0.9 0.42 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sugar_tr PF00083.19 ETS85921.1 - 4e-91 305.8 19.8 4.8e-91 305.6 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS85921.1 - 1.1e-30 106.6 18.6 1.6e-30 106.0 12.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS85922.1 - 3.8e-11 42.3 0.5 7.3e-11 41.4 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.12 ETS85923.1 - 3.4e-107 357.7 0.0 4.5e-107 357.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 ETS85923.1 - 1e-63 214.9 0.0 1.6e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 ETS85923.1 - 2.8e-52 176.6 0.1 5.7e-52 175.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS85923.1 - 1.2e-19 70.8 0.3 4.5e-19 68.9 0.2 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Hydrolase_3 PF08282.7 ETS85924.1 - 3.3e-13 49.7 0.0 5.3e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.8 ETS85924.1 - 2.4e-11 43.6 0.0 3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 ETS85924.1 - 0.00025 20.4 0.0 0.017 14.4 0.0 2.2 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 ETS85924.1 - 0.024 15.0 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS85924.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ISN1 PF06437.6 ETS85924.1 - 0.11 11.1 0.0 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase MFS_1 PF07690.11 ETS85925.1 - 1.5e-47 162.0 40.2 9e-46 156.1 28.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS85925.1 - 1.3e-21 76.4 18.6 1.3e-21 76.4 12.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS85925.1 - 2.9e-16 59.0 25.2 1.9e-15 56.3 7.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 ETS85925.1 - 1.4e-10 40.1 26.1 3.3e-06 25.7 1.7 3.8 2 1 2 4 4 4 3 MFS/sugar transport protein peroxidase PF00141.18 ETS85926.1 - 1.6e-27 96.4 5.2 4e-27 95.1 3.6 1.5 1 1 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 ETS85926.1 - 7.2e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) NIF PF03031.13 ETS85927.1 - 2.1e-28 98.9 0.1 7e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 ETS85927.1 - 2.7e-10 39.9 0.0 5.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 ETS85927.1 - 1.3e-07 31.6 0.0 2.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 ETS85927.1 - 6.8e-05 22.4 0.1 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 ETS85927.1 - 0.004 16.7 0.0 0.31 10.6 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.1 ETS85927.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 HlyD family secretion protein GRIM-19 PF06212.7 ETS85928.1 - 4.3e-10 39.3 0.2 9.1e-10 38.3 0.2 1.5 1 1 0 1 1 1 1 GRIM-19 protein Glyco_transf_28 PF03033.15 ETS85931.1 - 1.2e-25 89.9 0.0 2.3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 ETS85931.1 - 1.4e-25 88.5 1.3 2.6e-13 49.2 0.1 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 ETS85931.1 - 6.9e-14 51.9 0.0 3.6e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 ETS85931.1 - 3.3e-06 27.3 0.1 1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 ETS85931.1 - 2.7e-05 24.1 0.1 7.4e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 ETS85931.1 - 0.0002 20.0 0.0 0.0004 19.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 ETS85931.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Ribosomal_L18e PF00828.14 ETS85932.1 - 6.7e-35 120.2 0.1 9.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 ETS85933.1 - 7.7e-59 198.3 0.0 2e-58 197.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 ETS85933.1 - 2.9e-45 153.8 0.0 4.5e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 ETS85933.1 - 0.0013 18.6 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS85933.1 - 0.0056 16.1 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF572 PF04502.8 ETS85933.1 - 0.45 9.6 5.6 0.65 9.1 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PP2C PF00481.16 ETS85934.1 - 1.4e-26 93.4 0.0 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETS85934.1 - 0.039 13.3 0.2 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C ABM PF03992.11 ETS85935.1 - 0.0016 18.4 1.3 1.3 9.0 0.0 2.9 2 1 1 3 3 3 2 Antibiotic biosynthesis monooxygenase DUF4096 PF13340.1 ETS85936.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) zf-CCCH_2 PF14608.1 ETS85936.1 - 0.31 11.1 2.1 0.59 10.2 1.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Asn_synthase PF00733.16 ETS85937.1 - 1.5e-51 175.3 0.0 2.4e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS85937.1 - 1.7e-34 118.2 0.0 3e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS85937.1 - 9.1e-31 106.5 0.0 1.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 ETS85937.1 - 1.4e-08 34.1 0.0 2.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 ETS85937.1 - 0.0035 16.1 0.0 0.013 14.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 ETS85937.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 NAD synthase TPR_12 PF13424.1 ETS85938.1 - 0.0031 17.3 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85938.1 - 0.0038 17.8 2.5 0.51 11.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS85938.1 - 0.0058 16.5 1.7 0.41 10.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 ETS85938.1 - 0.0084 15.9 3.3 0.42 10.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85938.1 - 0.0086 15.8 0.1 6.6 6.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS85938.1 - 0.067 13.6 6.2 2.1 9.0 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 ETS85938.1 - 0.084 12.8 0.3 0.58 10.2 0.0 2.5 3 0 0 3 3 3 0 PPR repeat TPR_19 PF14559.1 ETS85938.1 - 0.2 11.9 1.9 16 5.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85938.1 - 0.35 11.6 5.3 2.6 8.9 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 ETS85938.1 - 0.47 10.4 2.0 0.61 10.1 0.1 2.1 3 0 0 3 3 3 0 PPR repeat family PNGaseA PF12222.3 ETS85939.1 - 1.3e-119 399.8 8.4 1.7e-119 399.5 5.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Leu_leader PF08054.6 ETS85939.1 - 0.18 11.4 0.4 0.42 10.2 0.3 1.6 1 0 0 1 1 1 0 Leucine operon leader peptide DUF367 PF04034.8 ETS85940.1 - 1.3e-47 160.6 0.1 1.9e-47 160.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 ETS85940.1 - 7.8e-11 41.3 1.7 1.7e-10 40.3 1.2 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.14 ETS85941.1 - 3.7e-45 153.0 0.0 1.7e-44 150.8 0.0 2.1 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 ETS85941.1 - 2e-22 79.0 0.1 5e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 ETS85941.1 - 2.2e-17 63.4 0.0 5.5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GTP_EFTU PF00009.22 ETS85942.1 - 7.1e-39 133.1 2.6 3.5e-38 130.9 1.8 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 ETS85942.1 - 8e-26 90.0 0.3 1.9e-25 88.8 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 ETS85942.1 - 1.3e-12 47.6 2.6 1.7e-07 31.2 0.0 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS85942.1 - 8.2e-08 32.2 0.1 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS85942.1 - 1.7e-05 25.2 0.1 4.1e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 ETS85942.1 - 2.2e-05 23.8 0.2 6e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.10 ETS85942.1 - 0.00018 21.1 0.0 0.0004 19.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 ETS85942.1 - 0.00023 20.4 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 ETS85942.1 - 0.00039 19.9 0.1 0.00093 18.7 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 ETS85942.1 - 0.0013 17.9 0.2 0.0037 16.5 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 ETS85942.1 - 0.0062 15.3 3.0 0.011 14.4 1.7 1.6 1 1 0 1 1 1 1 ArgK protein Dynamin_N PF00350.18 ETS85942.1 - 0.26 11.0 4.4 6.1 6.6 0.1 3.6 3 1 1 4 4 4 0 Dynamin family Choline_transpo PF04515.7 ETS85943.1 - 0.13 10.9 0.8 0.19 10.4 0.6 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter PP28 PF10252.4 ETS85944.1 - 2.7e-26 91.4 17.4 2.7e-26 91.4 12.0 3.1 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Ank_2 PF12796.2 ETS85945.1 - 3.8e-51 171.3 8.3 4.8e-21 74.9 0.4 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) HET PF06985.6 ETS85945.1 - 2.3e-37 128.2 0.2 4.9e-37 127.1 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 ETS85945.1 - 3.3e-32 108.6 3.7 2e-08 33.6 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 ETS85945.1 - 2.2e-24 83.0 2.8 0.00038 20.4 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 ETS85945.1 - 5.1e-24 84.1 0.4 2e-08 34.5 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS85945.1 - 9.9e-21 73.3 4.7 3.8e-09 36.4 0.1 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF2913 PF11140.3 ETS85945.1 - 0.037 13.3 0.2 0.078 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) DUF3654 PF12376.3 ETS85945.1 - 0.054 13.3 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) adh_short PF00106.20 ETS85946.1 - 9.1e-15 54.9 0.6 1.3e-14 54.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85946.1 - 1.7e-07 31.0 0.2 2.3e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS85946.1 - 1.5e-05 25.0 0.1 3.9e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS85946.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.18 ETS85947.1 - 3.6e-16 58.9 3.5 9.9e-16 57.4 2.4 1.8 1 1 0 1 1 1 1 FAD binding domain Ank_2 PF12796.2 ETS85948.1 - 4.8e-50 167.8 8.2 5.6e-14 52.2 0.0 9.2 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85948.1 - 7.2e-27 91.8 24.3 0.0026 17.5 0.1 13.9 17 0 0 17 17 17 7 Ankyrin repeat Ank_3 PF13606.1 ETS85948.1 - 1.2e-25 86.9 12.6 0.23 11.7 0.0 15.8 18 0 0 18 18 18 6 Ankyrin repeat Ank_4 PF13637.1 ETS85948.1 - 5.1e-20 71.4 19.5 0.0015 18.9 0.0 12.5 11 2 4 15 15 15 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS85948.1 - 4.3e-17 61.7 10.6 0.059 13.6 0.0 10.1 8 2 4 12 12 12 6 Ankyrin repeats (many copies) Phosphonate-bd PF12974.2 ETS85949.1 - 2.4e-19 69.6 0.0 3e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 ETS85949.1 - 0.0074 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Cnd1 PF12717.2 ETS85951.1 - 5e-55 186.0 2.2 3.9e-51 173.4 0.5 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 ETS85951.1 - 6.9e-54 182.0 2.3 1e-53 181.4 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 ETS85951.1 - 4.9e-11 42.7 1.1 5.9e-05 23.2 0.0 5.0 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 ETS85951.1 - 9.3e-08 31.5 5.5 0.12 12.5 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 ETS85951.1 - 1e-05 25.8 3.5 0.044 14.2 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 ETS85951.1 - 0.00078 19.2 0.0 0.34 10.8 0.0 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Pkinase PF00069.20 ETS85952.1 - 1.9e-45 155.0 0.0 6.6e-41 140.1 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS85952.1 - 5.2e-14 51.9 0.0 4.8e-08 32.3 0.0 3.4 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 ETS85952.1 - 2.6e-06 26.6 0.0 0.0049 15.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 ETS85952.1 - 3.4e-05 23.6 1.4 0.0092 15.7 0.0 3.4 3 1 1 4 4 4 2 Phosphotransferase enzyme family Daxx PF03344.10 ETS85952.1 - 1 7.7 16.5 1.3 7.3 11.4 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETS85952.1 - 3.3 5.5 17.6 4.8 4.9 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2235 PF09994.4 ETS85953.1 - 1.2e-67 228.1 0.0 1.7e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DAO PF01266.19 ETS85954.1 - 4.8e-34 117.8 0.3 1.7e-33 116.0 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS85954.1 - 6.6e-06 26.3 0.1 0.051 13.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS85954.1 - 6.5e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS85954.1 - 0.0001 22.2 0.0 0.003 17.4 0.0 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 ETS85954.1 - 0.00039 20.2 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 ETS85954.1 - 0.0011 19.3 0.7 0.0051 17.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS85954.1 - 0.0012 18.6 0.2 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 ETS85954.1 - 0.026 13.6 0.0 0.062 12.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS85954.1 - 0.1 11.9 0.1 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HET PF06985.6 ETS85955.1 - 6.3e-30 104.1 0.0 9.8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BcrAD_BadFG PF01869.15 ETS85957.1 - 0.029 13.6 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FAD_binding_3 PF01494.14 ETS85958.1 - 3.2e-20 72.5 0.0 1.2e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 ETS85958.1 - 0.00088 19.2 0.1 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 ETS85958.1 - 0.0013 17.6 0.0 0.024 13.4 0.0 2.2 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 ETS85958.1 - 0.0028 16.6 0.0 0.0091 14.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS85958.1 - 0.017 15.2 0.1 0.089 12.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS85958.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 ETS85958.1 - 0.025 14.9 0.1 0.078 13.4 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS85958.1 - 0.034 13.0 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 ETS85958.1 - 0.14 10.5 0.1 0.41 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 ETS85958.1 - 0.16 11.8 0.1 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pox_A9 PF04835.7 ETS85959.1 - 3.8 7.4 14.5 0.87 9.5 1.0 3.1 3 0 0 3 3 3 0 A9 protein conserved region MerC PF03203.9 ETS85959.1 - 7.6 6.9 11.7 0.44 10.9 3.0 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein FAD_binding_4 PF01565.18 ETS85960.1 - 1.5e-19 69.8 0.8 6.9e-19 67.7 0.2 2.1 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 ETS85960.1 - 9.3e-05 22.2 0.3 0.00023 20.9 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like DHquinase_I PF01487.10 ETS85960.1 - 0.034 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase DUF2686 PF10887.3 ETS85960.1 - 0.046 12.4 0.0 0.086 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) ketoacyl-synt PF00109.21 ETS85961.1 - 2.4e-70 236.9 0.9 3.8e-70 236.2 0.7 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS85961.1 - 1.4e-32 112.0 0.0 3.7e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 ETS85961.1 - 1.1e-23 84.0 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 ETS85961.1 - 1.2e-20 73.5 1.8 3.2e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 ETS85961.1 - 8.3e-19 67.9 0.0 2.5e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 ETS85961.1 - 1.2e-13 50.9 0.0 2.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 ETS85961.1 - 4.9e-11 42.6 0.0 1.3e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS85961.1 - 6.2e-10 39.4 0.0 2.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS85961.1 - 6.6e-10 38.7 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS85961.1 - 2.8e-06 27.8 0.0 1.5e-05 25.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS85961.1 - 3e-05 23.2 0.0 0.00012 21.3 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS85961.1 - 0.00019 21.4 0.0 0.00085 19.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS85961.1 - 0.0006 19.3 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 ETS85961.1 - 0.0083 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain HET PF06985.6 ETS85964.1 - 1.8e-06 28.1 0.1 0.0068 16.5 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.12 ETS85965.1 - 3.5e-12 45.2 7.7 0.00034 20.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS85965.1 - 5.8e-11 41.8 1.8 0.00013 21.5 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 ETS85965.1 - 5.2e-07 28.9 2.6 0.026 14.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS85965.1 - 8.5e-07 29.4 1.8 9e-05 23.0 0.1 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 ETS85965.1 - 1.8e-06 27.7 2.9 0.0039 17.0 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS85965.1 - 7.3e-06 26.2 4.1 0.0018 18.5 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS85965.1 - 4.1e-05 23.8 2.1 2.4 9.0 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS85965.1 - 0.0029 17.2 0.2 4.6 7.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS85965.1 - 0.0029 17.9 0.4 5.4 7.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS85965.1 - 0.047 13.5 1.0 29 4.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS85966.1 - 4.8e-11 42.4 12.8 0.0076 16.1 0.1 5.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 ETS85966.1 - 0.041 13.8 16.0 1.9 8.5 0.3 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat p450 PF00067.17 ETS85967.1 - 1.8e-50 171.8 0.0 2.4e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS85968.1 - 2.2e-43 148.3 28.8 2.2e-43 148.3 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS85968.1 - 1.8e-08 33.3 14.9 1.8e-08 33.3 10.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 ETS85968.1 - 0.3 9.1 18.0 0.0094 14.1 4.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector PAP2 PF01569.16 ETS85969.1 - 2.1e-19 69.4 0.8 2.1e-19 69.4 0.6 1.8 2 1 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.13 ETS85970.1 - 5.9e-10 38.4 3.6 6.9e-10 38.2 0.5 2.4 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85970.1 - 0.0041 16.9 9.8 0.0081 16.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 ETS85971.1 - 1.1e-66 225.2 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 ETS85972.1 - 3.5e-28 99.0 0.0 4.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS85972.1 - 3e-26 92.3 0.4 4e-26 91.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS85972.1 - 1.1e-10 41.4 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS85972.1 - 0.0017 17.7 0.6 0.0052 16.2 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 ETS85972.1 - 0.004 16.7 0.4 0.0061 16.1 0.3 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein TauD PF02668.11 ETS85973.1 - 8.8e-53 179.5 0.3 1.1e-52 179.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 4HBT_3 PF13622.1 ETS85974.1 - 3.5e-36 125.2 0.1 4.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos_C PF14008.1 ETS85975.1 - 8.2e-20 70.6 0.5 2.3e-19 69.1 0.3 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 ETS85975.1 - 9.8e-19 67.5 0.6 7.5e-18 64.6 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 ETS85975.1 - 1.6e-08 33.5 0.0 2.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase F-box-like PF12937.2 ETS85976.1 - 0.00035 20.2 1.9 0.00068 19.3 1.3 1.5 1 0 0 1 1 1 1 F-box-like CENP-B_dimeris PF09026.5 ETS85976.1 - 0.0027 17.9 4.1 0.0056 16.8 2.8 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain F-box PF00646.28 ETS85976.1 - 0.012 15.2 0.5 0.039 13.6 0.3 1.9 1 0 0 1 1 1 0 F-box domain Cwf_Cwc_15 PF04889.7 ETS85976.1 - 7.4 6.2 8.9 11 5.6 6.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PepX_C PF08530.5 ETS85977.1 - 2.6e-17 63.4 0.1 7.6e-17 61.9 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF3426 PF11906.3 ETS85977.1 - 0.0048 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) Peptidase_S15 PF02129.13 ETS85977.1 - 0.0051 16.2 0.4 0.11 11.8 0.1 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S15 PF02129.13 ETS85978.1 - 3.3e-24 85.7 0.4 5.4e-24 85.0 0.3 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 ETS85978.1 - 0.049 12.1 0.0 5 5.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2685 PF10886.3 ETS85979.1 - 0.0035 17.3 3.3 1.3 9.0 0.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2685) DUF4446 PF14584.1 ETS85979.1 - 1.7 8.5 3.8 1.7 8.4 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) p450 PF00067.17 ETS85980.1 - 1.6e-43 148.9 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS85981.1 - 6.2e-18 64.5 0.0 1.2e-16 60.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 ETS85983.1 - 7.7e-31 107.1 0.0 1.4e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS85984.1 - 4.3e-38 130.9 47.3 4.3e-38 130.9 32.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS85984.1 - 5.7e-11 41.3 16.5 5.7e-11 41.3 11.5 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF607 PF04678.8 ETS85984.1 - 0.068 13.0 0.5 0.16 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF3433 PF11915.3 ETS85985.1 - 4.7e-29 100.4 18.3 1.3e-22 79.7 0.4 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) COX2_TM PF02790.10 ETS85985.1 - 0.0029 17.5 0.6 4.6 7.2 0.0 3.1 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain HET PF06985.6 ETS85986.1 - 7.5e-22 77.9 0.0 1.7e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cupin_1 PF00190.17 ETS85987.1 - 1.2e-29 102.6 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 ETS85987.1 - 2e-23 81.6 1.3 1e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 ETS85987.1 - 5.4e-08 32.6 0.6 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 ETS85987.1 - 2e-07 30.2 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 ETS85987.1 - 4.9e-06 26.2 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 2 Cupin SBP56 PF05694.6 ETS85988.1 - 1.1e-05 24.2 0.0 0.00013 20.5 0.0 2.4 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 ETS85988.1 - 9.6e-05 21.6 0.1 0.39 9.7 0.0 2.9 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller NHL PF01436.16 ETS85988.1 - 0.022 14.6 0.1 0.89 9.6 0.0 3.3 3 0 0 3 3 3 0 NHL repeat SGL PF08450.7 ETS85988.1 - 0.13 11.6 0.1 9.6 5.4 0.0 2.6 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region An_peroxidase PF03098.10 ETS85989.1 - 5.8e-96 321.9 0.0 1.5e-93 314.0 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 ETS85989.1 - 6.1e-05 21.7 0.0 0.00022 19.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 MAPEG PF01124.13 ETS85990.1 - 3.1e-20 72.0 5.9 3.7e-20 71.8 4.1 1.2 1 0 0 1 1 1 1 MAPEG family adh_short PF00106.20 ETS85991.1 - 2.9e-08 33.8 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh PF00389.25 ETS85991.1 - 0.058 12.8 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans_2 PF11951.3 ETS85992.1 - 2.5e-23 82.2 0.0 5.7e-23 81.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS85992.1 - 1.4e-06 28.1 12.4 3.4e-06 26.8 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 ETS85993.1 - 8.3e-163 541.9 0.0 1e-162 541.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS85993.1 - 7.8e-21 74.0 0.1 2.9e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 ETS85993.1 - 1.5e-12 47.4 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 ETS85994.1 - 7.8e-54 182.8 43.6 9.6e-54 182.5 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS85994.1 - 1.4e-24 86.3 36.4 1.9e-24 85.9 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 ETS85994.1 - 0.14 12.0 3.4 0.24 11.2 0.0 2.7 2 0 0 2 2 2 0 Gram positive anchor Aldedh PF00171.17 ETS85995.1 - 6.8e-184 611.5 0.1 7.7e-184 611.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 ETS85995.1 - 0.13 11.4 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glyoxalase_2 PF12681.2 ETS85996.1 - 4.2e-08 33.7 0.0 5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Ank_2 PF12796.2 ETS85999.1 - 3.9e-59 196.9 7.0 3.9e-18 65.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS85999.1 - 1.5e-42 141.2 9.9 1.3e-06 27.9 0.0 9.3 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 ETS85999.1 - 3.8e-30 100.9 0.3 0.00025 20.9 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 ETS85999.1 - 2.4e-22 78.4 5.3 1.9e-05 24.7 0.2 7.8 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS85999.1 - 2.1e-21 75.8 1.2 0.0039 17.6 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.7 ETS85999.1 - 6.2e-12 45.4 0.2 3.5e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 ETS85999.1 - 0.00031 20.8 0.0 0.0019 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS85999.1 - 0.00054 19.9 0.1 0.0026 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Syntaxin_2 PF14523.1 ETS85999.1 - 0.022 14.7 0.6 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Syntaxin-like protein NB-ARC PF00931.17 ETS85999.1 - 0.025 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 ETS85999.1 - 0.16 11.9 0.0 0.5 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyco_hydro_61 PF03443.9 ETS86000.1 - 6.1e-82 274.6 0.2 6.1e-82 274.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 NICE-3 PF07406.6 ETS86001.1 - 0.00012 21.6 0.0 0.091 12.2 0.0 2.5 2 0 0 2 2 2 2 NICE-3 protein DUF4129 PF13559.1 ETS86001.1 - 0.00068 19.5 0.1 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Ndc1_Nup PF09531.5 ETS86002.1 - 1.3e-130 436.6 0.0 1.5e-130 436.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 ETS86003.1 - 9.7e-22 76.9 2.2 9.7e-22 76.9 1.6 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 ETS86003.1 - 2.8e-15 55.7 2.3 2.8e-15 55.7 1.6 2.6 5 0 0 5 5 4 1 SNARE domain Synaptobrevin PF00957.16 ETS86003.1 - 0.036 13.6 0.4 0.036 13.6 0.3 2.3 2 1 1 3 3 3 0 Synaptobrevin Gp-FAR-1 PF05823.7 ETS86003.1 - 0.043 13.7 2.0 0.056 13.4 0.3 1.8 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TMPIT PF07851.8 ETS86003.1 - 0.059 12.4 3.6 0.97 8.4 0.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein Spectrin PF00435.16 ETS86003.1 - 0.2 11.9 13.5 0.43 10.8 3.3 3.0 1 1 2 3 3 3 0 Spectrin repeat Herpes_US9 PF06072.6 ETS86003.1 - 0.28 11.0 1.4 3.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF1664 PF07889.7 ETS86003.1 - 0.39 10.5 5.4 1.5 8.6 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) T2SF PF00482.18 ETS86003.1 - 0.7 9.8 4.1 2.5 8.0 1.8 2.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DUF3450 PF11932.3 ETS86003.1 - 0.8 8.9 17.0 0.72 9.0 6.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF883 PF05957.8 ETS86003.1 - 0.82 10.1 0.0 0.82 10.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.7 ETS86003.1 - 1.2 7.4 9.5 2.2 6.6 6.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Enkurin PF13864.1 ETS86003.1 - 9.8 6.4 8.8 1.3 9.3 0.1 3.0 2 1 1 3 3 3 0 Calmodulin-binding 60KD_IMP PF02096.15 ETS86004.1 - 1.7e-08 34.3 0.0 2.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 ETS86005.1 - 7.7e-19 67.7 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS86005.1 - 1.1e-06 28.7 0.0 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 ETS86005.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 MFS_1 PF07690.11 ETS86006.1 - 7.2e-14 51.2 30.1 7.2e-14 51.2 20.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 ETS86006.1 - 1.1e-07 31.4 8.5 1.1e-07 31.4 5.9 3.1 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 ETS86006.1 - 0.00022 19.9 11.2 0.00022 19.9 7.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TauD PF02668.11 ETS86007.1 - 6.4e-33 114.4 0.0 9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box PF00646.28 ETS86008.1 - 7.6e-05 22.2 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS86008.1 - 0.00029 20.4 1.2 0.00035 20.2 0.1 1.7 2 0 0 2 2 2 1 F-box-like EthD PF07110.6 ETS86009.1 - 6.4e-10 39.8 0.0 8.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 EthD domain Ank_2 PF12796.2 ETS86010.1 - 8.7e-11 42.0 0.1 2.8e-09 37.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86010.1 - 5e-10 38.6 0.5 0.0003 20.4 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 ETS86010.1 - 1.3e-08 35.1 0.1 0.00069 20.0 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86010.1 - 7.9e-06 25.6 0.2 0.74 10.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 ETS86010.1 - 0.00019 21.5 0.2 0.0081 16.3 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Tyrosinase PF00264.15 ETS86011.1 - 8.4e-40 137.2 8.6 1.1e-39 136.8 5.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Hemocyanin_M PF00372.14 ETS86011.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Kelch_1 PF01344.20 ETS86012.1 - 0.00014 21.3 0.4 0.94 9.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 ETS86012.1 - 0.0015 18.6 0.9 6.6 7.0 0.0 3.2 3 0 0 3 3 3 2 Kelch motif SoxD PF04267.7 ETS86012.1 - 0.039 13.7 0.6 0.56 10.0 0.1 2.0 1 1 1 2 2 2 0 Sarcosine oxidase, delta subunit family Glyco_transf_9 PF01075.12 ETS86013.1 - 0.035 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) adh_short PF00106.20 ETS86014.1 - 9.7e-12 45.1 0.4 3.6e-11 43.2 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86014.1 - 0.00061 19.6 0.1 0.0014 18.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86014.1 - 0.00094 18.8 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86014.1 - 0.0081 15.6 0.2 0.21 10.9 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 ETS86014.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain EthD PF07110.6 ETS86015.1 - 7.3e-09 36.4 0.0 9.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain PK PF00224.16 ETS86015.1 - 0.092 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Trp_DMAT PF11991.3 ETS86017.1 - 1.1e-78 265.0 0.0 1.3e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Cupin_2 PF07883.6 ETS86018.1 - 3.2e-05 23.3 0.1 4.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 ETS86019.1 - 2.2e-10 40.6 0.2 3.7e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS86019.1 - 9.5e-06 25.7 0.6 1.9e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS86019.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.2 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 ETS86019.1 - 2.4e-05 23.7 1.7 7.7e-05 22.0 1.5 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 ETS86019.1 - 0.044 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS86019.1 - 0.12 11.8 0.2 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 ETS86020.1 - 1.1e-21 76.7 1.1 2.9e-21 75.4 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS86020.1 - 4.6e-05 23.2 0.2 0.00015 21.6 0.1 2.0 1 0 0 1 1 1 1 Berberine and berberine like DUF2529 PF10740.4 ETS86020.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) Fungal_trans_2 PF11951.3 ETS86021.1 - 7.6e-36 123.5 0.9 1e-35 123.1 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS86022.1 - 4.8e-10 39.6 0.0 7.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS86022.1 - 5.7e-05 23.2 0.1 0.0021 18.0 0.1 2.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 ETS86022.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86022.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 ETS86022.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 ETS86023.1 - 5.5e-09 35.8 6.4 1.4e-08 34.5 4.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS86023.1 - 1.4e-05 24.0 0.0 5e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.6 ETS86023.1 - 7.2 5.9 6.8 12 5.1 4.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ank_2 PF12796.2 ETS86024.1 - 9.1e-10 38.7 0.5 0.00016 21.9 0.0 4.8 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS86024.1 - 6e-08 32.9 1.5 0.13 12.8 0.0 4.3 4 0 0 4 4 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 ETS86024.1 - 2.3e-07 30.5 0.0 1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 ETS86024.1 - 1e-05 25.6 0.1 0.82 10.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS86024.1 - 0.00019 21.4 0.0 0.00086 19.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Ank_3 PF13606.1 ETS86024.1 - 0.00073 19.5 1.1 4.4 7.8 0.0 5.6 5 0 0 5 5 4 1 Ankyrin repeat NB-ARC PF00931.17 ETS86024.1 - 0.0029 16.4 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF2320 PF10082.4 ETS86024.1 - 0.0059 15.3 0.0 0.0095 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2320) AAA_22 PF13401.1 ETS86024.1 - 0.0078 16.3 0.0 0.056 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank PF00023.25 ETS86024.1 - 0.018 14.8 0.1 52 3.9 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat AAA PF00004.24 ETS86024.1 - 0.062 13.5 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS86024.1 - 0.12 12.1 0.1 0.42 10.3 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain Ank_2 PF12796.2 ETS86025.1 - 1.1e-32 112.1 1.4 6.1e-16 58.5 0.1 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86025.1 - 1.4e-22 78.3 6.4 7.5e-06 25.4 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 ETS86025.1 - 6.6e-19 67.9 6.3 6.8e-09 36.0 0.0 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86025.1 - 3.2e-16 58.9 3.6 6.6e-06 26.2 0.0 6.0 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86025.1 - 1.4e-14 52.7 8.4 0.0045 17.1 0.0 7.5 9 0 0 9 9 9 3 Ankyrin repeat Ank_2 PF12796.2 ETS86026.1 - 4.4e-15 55.7 0.0 1.6e-07 31.5 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86026.1 - 3.3e-08 32.9 0.0 0.00098 18.8 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 ETS86026.1 - 6.9e-05 22.7 0.0 0.086 13.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 ETS86026.1 - 0.0025 18.2 0.0 0.22 12.0 0.0 3.9 3 2 2 5 5 5 1 Ankyrin repeats (many copies) DNA_pol_A_exo1 PF01612.15 ETS86027.1 - 6e-11 42.1 0.0 1.4e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_2 PF03175.8 ETS86027.1 - 0.026 13.2 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Big_2 PF02368.13 ETS86027.1 - 0.19 11.6 10.4 0.49 10.3 7.2 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 2) FAR1 PF03101.10 ETS86028.1 - 3.1e-05 24.4 0.2 5.5e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF2360 PF10152.4 ETS86028.1 - 0.0047 17.2 0.5 0.0077 16.5 0.1 1.6 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Hemagglutinin PF00509.13 ETS86028.1 - 0.0066 14.6 0.0 0.0078 14.4 0.0 1.1 1 0 0 1 1 1 1 Haemagglutinin AFT PF08731.6 ETS86028.1 - 0.0088 16.2 0.2 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Transcription factor AFT Snapin_Pallidin PF14712.1 ETS86028.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Herpes_capsid PF06112.6 ETS86028.1 - 0.031 14.2 0.5 0.05 13.6 0.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Baculo_PEP_C PF04513.7 ETS86028.1 - 0.064 13.0 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GP41 PF00517.12 ETS86028.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF1664 PF07889.7 ETS86028.1 - 0.21 11.3 0.9 0.38 10.5 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 ETS86028.1 - 0.23 10.8 0.9 13 5.2 0.6 2.3 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TBPIP PF07106.8 ETS86029.1 - 0.018 14.5 1.1 0.023 14.2 0.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TarH PF02203.10 ETS86029.1 - 0.033 14.0 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF2340 PF10209.4 ETS86029.1 - 0.036 14.2 0.1 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) DLD PF14878.1 ETS86029.1 - 0.12 12.5 0.4 0.5 10.4 0.3 1.9 1 1 0 1 1 1 0 Death-like domain of SPT6 YscO PF07321.7 ETS86029.1 - 0.21 11.3 2.8 0.2 11.4 0.3 1.8 1 1 1 2 2 2 0 Type III secretion protein YscO eIF-3c_N PF05470.7 ETS86030.1 - 7.7e-177 589.0 22.1 6.3e-145 483.6 1.8 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 ETS86030.1 - 3.8e-14 52.8 0.0 2.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 PCI domain CENP-T PF15511.1 ETS86030.1 - 0.00046 19.5 9.4 0.00046 19.5 6.5 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 ETS86030.1 - 0.41 8.6 18.9 0.61 8.0 13.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 ETS86030.1 - 2.3 6.6 23.1 3.6 5.9 16.0 1.3 1 0 0 1 1 1 0 Daxx Family GRP PF07172.6 ETS86030.1 - 7.7 7.0 19.6 0.065 13.7 7.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family Hemerythrin PF01814.18 ETS86031.1 - 1.5e-15 57.4 4.1 2.1e-15 57.0 2.9 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain WD40 PF00400.27 ETS86033.1 - 7.5e-19 66.8 2.1 2.5e-07 30.3 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat HET PF06985.6 ETS86033.1 - 3.2e-18 66.2 10.1 3.2e-18 66.2 7.0 3.1 3 1 0 3 3 2 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS86033.1 - 1e-11 44.7 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS86033.1 - 4.5e-05 23.5 0.0 0.0002 21.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 ETS86033.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 ETS86033.1 - 0.006 16.2 0.0 7.6 6.3 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Arch_ATPase PF01637.13 ETS86033.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_30 PF13604.1 ETS86033.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS86033.1 - 0.025 15.3 0.0 0.23 12.3 0.0 2.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 ETS86033.1 - 0.032 13.0 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 ETS86033.1 - 0.039 13.6 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 ETS86033.1 - 0.042 14.1 0.1 0.14 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 ETS86034.1 - 1.2e-26 93.2 23.4 1.2e-26 93.2 16.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF771 PF05595.6 ETS86034.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF771) Aldo_ket_red PF00248.16 ETS86035.1 - 3.2e-25 88.5 0.0 3.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_44 PF14641.1 ETS86035.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 PAN_4 PF14295.1 ETS86036.1 - 5e-05 22.9 0.8 0.00016 21.2 0.5 1.8 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.21 ETS86036.1 - 0.0015 18.2 0.4 0.0026 17.4 0.3 1.4 1 0 0 1 1 1 1 PAN domain XFP PF03894.10 ETS86037.1 - 0.092 12.3 0.2 8.8 5.8 0.0 2.5 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase CFEM PF05730.6 ETS86038.1 - 4.8e-12 45.5 6.0 8.5e-12 44.7 4.2 1.4 1 0 0 1 1 1 1 CFEM domain DUF3474 PF11960.3 ETS86039.1 - 0.0084 16.1 1.9 0.037 14.0 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) EHN PF06441.7 ETS86040.1 - 3.1e-38 130.1 0.2 2.5e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 ETS86040.1 - 1.8e-07 31.2 0.5 1.8e-06 28.0 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS86040.1 - 0.0015 18.1 0.2 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold MatE PF01554.13 ETS86041.1 - 4.7e-51 172.6 25.4 7.3e-31 106.9 6.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 ETS86041.1 - 0.0011 18.7 2.9 0.0011 18.7 2.0 4.8 1 1 3 4 4 4 2 Polysaccharide biosynthesis C-terminal domain AA_permease PF00324.16 ETS86043.1 - 5.3e-109 364.7 47.5 6.6e-109 364.3 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS86043.1 - 1.9e-33 115.6 48.3 2.3e-33 115.4 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 ETS86043.1 - 7.3 7.0 13.2 16 5.9 2.5 3.6 3 1 0 3 3 3 0 Early E3 14.5 kDa protein MFS_1 PF07690.11 ETS86044.1 - 1.3e-34 119.4 41.2 1.3e-34 119.4 28.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86044.1 - 2.2e-11 42.9 30.4 9.3e-06 24.4 7.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 ETS86044.1 - 7.9e-07 27.8 19.9 7.9e-07 27.8 13.8 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 ETS86044.1 - 0.00049 19.8 1.1 0.092 12.5 0.1 3.1 2 0 0 2 2 2 2 MFS_1 like family Abhydrolase_1 PF00561.15 ETS86045.1 - 6.2e-11 42.2 0.0 2.1e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS86045.1 - 6.7e-09 35.9 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS86045.1 - 0.0058 16.3 0.1 0.11 12.2 0.1 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS86045.1 - 0.017 14.3 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TPR_2 PF07719.12 ETS86046.1 - 0.039 13.8 1.1 0.085 12.8 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 ETS86046.1 - 0.068 13.1 0.2 0.2 11.6 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat LCCL PF03815.14 ETS86047.1 - 1.9e-19 69.3 1.3 3.1e-19 68.7 0.9 1.3 1 0 0 1 1 1 1 LCCL domain TGT PF01702.13 ETS86048.1 - 2.3e-39 135.1 0.0 3.2e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.15 ETS86049.1 - 2e-64 217.8 0.0 3.3e-64 217.1 0.0 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 ETS86049.1 - 1.7e-05 24.3 0.1 3.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 ETS86049.1 - 3.8e-05 23.0 0.0 9.3e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 ETS86049.1 - 0.024 13.0 0.2 0.042 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) AA_permease_2 PF13520.1 ETS86050.1 - 9.6e-51 172.6 56.5 1.2e-50 172.3 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS86050.1 - 1.8e-23 82.6 49.5 2.4e-23 82.2 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.15 ETS86051.1 - 1.3e-163 544.6 0.0 1.5e-163 544.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 ETS86051.1 - 2.5e-07 30.6 0.1 6.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 ETS86051.1 - 2.2e-05 24.4 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.13 ETS86052.1 - 1.2e-13 50.5 0.4 2.6e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain YscO PF07321.7 ETS86052.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Type III secretion protein YscO ADH_N PF08240.7 ETS86053.1 - 6.8e-31 106.2 1.0 1.2e-30 105.5 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS86053.1 - 6.4e-13 48.3 0.0 9.3e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 ETS86053.1 - 0.048 13.7 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_N PF00456.16 ETS86054.1 - 5.4e-118 393.6 0.0 7.1e-118 393.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 ETS86054.1 - 1.4e-38 132.1 0.0 2.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 ETS86054.1 - 3.4e-10 39.3 0.0 1.9e-08 33.5 0.0 2.8 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 ETS86054.1 - 1.4e-06 28.2 0.0 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 ETS86054.1 - 0.00022 20.8 1.1 0.0016 18.0 0.6 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 ETS86054.1 - 0.0018 17.0 0.1 0.0031 16.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Fungal_trans_2 PF11951.3 ETS86055.1 - 7.6e-14 51.0 1.5 2.3e-13 49.5 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS86055.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain 2TM PF13239.1 ETS86056.1 - 0.00055 19.9 0.5 0.0012 18.9 0.3 1.5 1 0 0 1 1 1 1 2TM domain zf-C2H2_4 PF13894.1 ETS86056.1 - 0.0038 17.4 4.5 1.4 9.3 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS86056.1 - 0.024 14.9 5.3 1.4 9.3 1.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_2 PF13347.1 ETS86056.1 - 0.1 10.9 0.3 0.15 10.3 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein zf-C2H2_jaz PF12171.3 ETS86056.1 - 0.12 12.6 0.4 0.3 11.3 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Fungal_trans_2 PF11951.3 ETS86057.1 - 0.13 10.8 2.4 0.47 9.0 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain End_beta_barrel PF12195.3 ETS86057.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase GMC_oxred_C PF05199.8 ETS86059.1 - 3.3e-26 92.3 0.0 6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS86059.1 - 4.7e-24 85.0 0.0 8.4e-22 77.6 0.0 3.0 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS86059.1 - 0.0023 17.8 0.1 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2190 PF09956.4 ETS86059.1 - 0.0031 17.2 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) DAO PF01266.19 ETS86059.1 - 0.007 15.3 0.9 0.23 10.3 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86059.1 - 0.026 14.5 0.5 0.093 12.7 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS86059.1 - 0.031 13.1 1.2 0.069 11.9 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 ETS86059.1 - 0.031 14.3 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS86059.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 ETS86059.1 - 0.15 10.4 0.3 0.3 9.5 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein CFEM PF05730.6 ETS86060.1 - 5.5e-11 42.1 9.4 1.1e-10 41.1 6.5 1.5 1 0 0 1 1 1 1 CFEM domain Fungal_trans_2 PF11951.3 ETS86061.1 - 1.9e-06 26.7 0.3 5.6e-06 25.2 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 ETS86062.1 - 3.6e-25 88.7 0.0 5.6e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS86062.1 - 3.7e-20 72.0 0.0 6.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 ETS86063.1 - 3.2e-92 309.4 38.7 4e-92 309.0 26.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-LITAF-like PF10601.4 ETS86064.1 - 0.0092 15.8 0.6 0.013 15.3 0.0 1.5 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Aldo_ket_red PF00248.16 ETS86065.1 - 3.1e-63 213.2 0.0 3.6e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_tail_X PF05489.7 ETS86065.1 - 0.014 14.8 0.1 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 Phage Tail Protein X Alginate_lyase PF05426.7 ETS86071.1 - 6.9e-09 35.4 6.3 1.8e-08 34.0 4.3 1.6 1 1 0 1 1 1 1 Alginate lyase Fasciclin PF02469.17 ETS86072.1 - 1.7e-19 70.0 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF1931 PF09123.6 ETS86072.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Melibiase PF02065.13 ETS86073.1 - 2.6e-24 85.6 0.1 1.2e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 ETS86073.1 - 0.00036 19.7 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Raffinose_syn PF05691.7 ETS86073.1 - 0.0085 13.6 0.1 0.011 13.3 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF4431 PF14485.1 ETS86073.1 - 0.046 13.3 0.1 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) HTH_29 PF13551.1 ETS86074.1 - 0.00059 19.9 2.3 0.0014 18.7 1.7 1.6 1 1 0 1 1 1 1 Winged helix-turn helix Qn_am_d_aII PF14930.1 ETS86074.1 - 0.0014 18.5 0.7 0.0022 17.9 0.5 1.3 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain II HTH_38 PF13936.1 ETS86074.1 - 0.0027 17.2 0.4 0.0055 16.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 ETS86074.1 - 0.0046 16.2 1.3 0.0073 15.5 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Peptidase_M3_N PF08439.5 ETS86074.1 - 0.0068 16.4 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Oligopeptidase F DUF3489 PF11994.3 ETS86074.1 - 0.0089 15.9 0.4 0.02 14.8 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3489) UPF0561 PF10573.4 ETS86074.1 - 0.009 15.8 1.6 0.009 15.8 1.1 1.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0561 Caldesmon PF02029.10 ETS86074.1 - 0.025 12.9 4.5 0.034 12.5 3.1 1.2 1 0 0 1 1 1 0 Caldesmon Cytochrom_C PF00034.16 ETS86074.1 - 0.07 13.9 0.1 0.1 13.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c HTH_32 PF13565.1 ETS86074.1 - 0.096 13.5 1.6 0.85 10.4 1.1 2.2 1 1 1 2 2 2 0 Homeodomain-like domain CsbD PF05532.7 ETS86074.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 CsbD-like Glyco_hydro_88 PF07470.8 ETS86075.1 - 1.7e-22 79.8 1.4 2.2e-22 79.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 ETS86076.1 - 1.1e-18 67.0 0.0 2.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS86077.1 - 1.8e-33 115.7 26.1 9.1e-33 113.4 18.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 ETS86078.1 - 6.7e-22 77.6 0.5 9.1e-13 48.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) HET PF06985.6 ETS86078.1 - 1.1e-21 77.4 0.0 2.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 ETS86078.1 - 5.2e-17 60.7 0.9 2.7e-07 30.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 ETS86078.1 - 5.3e-14 52.2 0.5 1.9e-08 34.6 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86078.1 - 2e-12 46.9 0.3 2.2e-08 34.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86078.1 - 1.9e-10 39.9 0.1 0.0073 16.4 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat p450 PF00067.17 ETS86079.1 - 4.4e-70 236.4 0.0 5.8e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 ETS86080.1 - 9.8e-25 86.8 0.0 1.8e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86080.1 - 5.4e-23 81.2 0.0 9.2e-23 80.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86080.1 - 6.9e-20 71.3 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS86080.1 - 5.8e-17 61.5 0.0 2.1e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS86080.1 - 4.6e-16 59.1 0.0 8.5e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86080.1 - 7.9e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86080.1 - 1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86080.1 - 2.3e-11 43.7 0.0 4.4e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS86080.1 - 1.1e-09 38.1 0.1 2.2e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 ETS86080.1 - 6.5e-09 35.3 0.0 9.2e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 ETS86080.1 - 2.1e-08 33.7 0.0 3.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 ETS86080.1 - 3.1e-07 29.7 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 ETS86080.1 - 5.8e-05 23.8 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 ETS86080.1 - 0.00012 21.0 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin PrmA PF06325.8 ETS86080.1 - 0.00029 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 ETS86080.1 - 0.00071 18.0 0.0 0.001 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 ETS86080.1 - 0.0043 16.1 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_9 PF08003.6 ETS86080.1 - 0.0068 15.1 0.0 0.013 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.6 ETS86080.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) ADH_zinc_N PF00107.21 ETS86080.1 - 0.011 15.2 0.0 0.053 13.0 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_3 PF01596.12 ETS86080.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase GCD14 PF08704.5 ETS86080.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.7 ETS86080.1 - 0.049 12.4 0.0 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase RrnaAD PF00398.15 ETS86080.1 - 0.056 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 ETS86080.1 - 0.057 13.1 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 ETS86080.1 - 0.072 12.3 0.0 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 ETS86080.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.8 ETS86080.1 - 0.16 11.2 0.0 0.77 9.0 0.0 1.9 1 1 1 2 2 2 0 Histone methylation protein DOT1 MFS_1 PF07690.11 ETS86082.1 - 1.8e-48 165.0 39.1 1.8e-48 165.0 27.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86082.1 - 1.1e-15 57.2 15.7 1.1e-15 57.2 10.9 1.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 ETS86082.1 - 5.9e-08 31.3 3.8 9.8e-08 30.6 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS86082.1 - 1.5e-05 23.3 1.8 2.3e-05 22.7 1.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 ETS86082.1 - 0.0085 14.2 7.4 0.78 7.7 5.1 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRIQK PF15168.1 ETS86082.1 - 5.5 7.0 5.7 25 4.8 3.2 2.7 2 1 0 2 2 2 0 Triple QxxK/R motif-containing protein family Octopine_DH PF02317.12 ETS86083.1 - 5.6e-37 126.7 0.0 8e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 ETS86083.1 - 2.2e-11 43.7 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 ETS86083.1 - 1.3e-05 25.5 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 ETS86083.1 - 3.6e-05 23.6 0.1 7.9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 ETS86083.1 - 0.00016 21.1 0.1 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETS86083.1 - 0.00057 19.8 0.0 0.0011 18.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 ETS86083.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS86083.1 - 0.0044 15.5 0.0 0.0096 14.4 0.0 1.5 1 1 1 2 2 2 1 HI0933-like protein DAO PF01266.19 ETS86083.1 - 0.015 14.1 0.0 0.078 11.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS86083.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 ETS86083.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.7 ETS86083.1 - 0.031 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 ETS86083.1 - 0.038 12.8 0.1 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS86083.1 - 0.038 14.0 0.1 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pec_lyase_C PF00544.14 ETS86084.1 - 1.5e-16 60.5 6.8 2.7e-16 59.6 4.7 1.4 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_43 PF04616.9 ETS86085.1 - 3.3e-37 128.1 0.1 5.5e-37 127.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 ETS86086.1 - 5.3e-87 292.2 21.9 4e-86 289.3 15.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86086.1 - 5.2e-23 81.3 11.0 5.2e-23 81.3 7.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily HET PF06985.6 ETS86087.1 - 1.9e-29 102.5 0.1 2.7e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86089.1 - 5.9e-33 113.9 0.0 1.1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GP41 PF00517.12 ETS86090.1 - 0.022 14.2 1.1 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 Retroviral envelope protein IncA PF04156.9 ETS86090.1 - 0.14 11.7 2.5 0.17 11.4 1.3 1.5 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 ETS86090.1 - 1.5 8.3 10.8 0.33 10.4 4.1 2.4 2 0 0 2 2 2 0 Septum formation initiator CorA PF01544.13 ETS86091.1 - 1.6e-10 40.5 2.8 4e-10 39.1 1.9 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 ETS86091.1 - 0.00011 21.5 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 ETS86091.1 - 0.00013 21.9 1.0 0.00047 20.1 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Claudin_2 PF13903.1 ETS86091.1 - 0.053 13.2 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 ETS86091.1 - 0.36 10.3 21.9 0.22 11.0 11.3 2.7 3 0 0 3 3 3 0 IncA protein FUSC-like PF12805.2 ETS86091.1 - 0.93 8.3 3.9 2 7.2 2.7 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS FUSC PF04632.7 ETS86091.1 - 2.5 6.4 6.7 4.7 5.5 4.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2434 PF10361.4 ETS86092.1 - 0.039 13.0 0.2 0.039 13.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2434) GFA PF04828.9 ETS86093.1 - 8.5e-21 73.7 0.4 1.8e-20 72.7 0.2 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 ETS86093.1 - 0.004 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L27 PF01016.14 ETS86094.1 - 1.8e-26 91.6 0.1 3.5e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF2076 PF09849.4 ETS86095.1 - 0.0069 16.4 0.0 0.0069 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) IPP-2 PF04979.9 ETS86096.1 - 3.1e-12 46.8 8.2 3.1e-12 46.8 5.7 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SAGA-Tad1 PF12767.2 ETS86096.1 - 0.4 10.3 7.3 1.5 8.4 5.1 1.9 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit UvdE PF03851.9 ETS86097.1 - 3.8e-114 380.3 0.0 4.8e-114 380.0 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Adeno_terminal PF02459.10 ETS86097.1 - 1.3 7.0 5.2 0.16 10.1 0.7 1.4 2 0 0 2 2 2 0 Adenoviral DNA terminal protein SET PF00856.23 ETS86098.1 - 4.8e-16 59.4 0.0 1.3e-15 58.0 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 ETS86098.1 - 3e-05 23.9 0.2 7e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding GST_N_3 PF13417.1 ETS86099.1 - 5.8e-24 84.1 0.0 1.2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS86099.1 - 1.3e-17 63.4 0.0 3.2e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS86099.1 - 2.6e-07 30.7 0.0 6.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS86099.1 - 1.1e-06 28.4 0.2 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS86099.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 ETS86099.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin MFS_1 PF07690.11 ETS86101.1 - 5.9e-09 35.0 22.9 5.9e-09 35.0 15.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MauE PF07291.6 ETS86101.1 - 0.045 13.3 3.0 0.072 12.7 0.1 2.3 2 0 0 2 2 2 0 Methylamine utilisation protein MauE UNC-93 PF05978.11 ETS86101.1 - 0.57 9.6 14.5 0.016 14.6 4.1 2.7 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Glycos_transf_1 PF00534.15 ETS86102.1 - 9e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 ETS86102.1 - 3.7e-07 30.3 0.0 7.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 ETS86102.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF3461 PF11944.3 ETS86103.1 - 0.11 12.3 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Sialidase_penC PF12135.3 ETS86103.1 - 0.5 10.0 7.1 0.051 13.1 1.2 2.0 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain Tape_meas_lam_C PF09718.5 ETS86104.1 - 0.0014 18.5 2.5 0.0014 18.5 1.7 3.2 1 1 2 4 4 4 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TOBE_2 PF08402.5 ETS86104.1 - 8.9 6.3 9.3 20 5.2 1.0 2.9 1 1 2 3 3 3 0 TOBE domain Acetyltransf_1 PF00583.19 ETS86105.1 - 3.4e-17 62.2 0.0 4.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS86105.1 - 7.2e-10 38.8 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS86105.1 - 1.1e-07 31.7 0.0 3.5e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS86105.1 - 1.4e-07 31.6 0.0 1.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS86105.1 - 2.5e-05 23.9 0.1 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 ETS86105.1 - 3.1e-05 24.1 0.0 4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS86105.1 - 5e-05 23.2 0.0 6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS86105.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 ETS86105.1 - 0.063 13.1 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 ETS86106.1 - 1.1e-28 99.9 29.9 1.1e-28 99.9 20.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS86106.1 - 0.0049 16.6 0.8 0.015 15.0 0.3 2.0 2 0 0 2 2 2 1 MFS_1 like family SBP_bac_5 PF00496.17 ETS86107.1 - 3.1e-42 144.7 0.0 4.1e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle p450 PF00067.17 ETS86108.1 - 2.8e-81 273.3 0.0 4e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 ETS86109.1 - 6.5e-24 84.9 0.1 8e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS86109.1 - 0.00086 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 CsiD PEP_mutase PF13714.1 ETS86110.1 - 2e-36 125.3 0.1 2.4e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 ETS86110.1 - 1.7e-18 66.1 0.1 2.3e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family VWA_2 PF13519.1 ETS86111.1 - 0.0039 17.3 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain SpoVIF PF14069.1 ETS86111.1 - 0.091 12.5 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F ADH_zinc_N PF00107.21 ETS86112.1 - 5.1e-23 81.0 0.1 9.5e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS86112.1 - 5.4e-11 42.2 0.2 2.8e-10 39.9 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS86112.1 - 1.6e-10 41.9 0.0 3.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 ETS86112.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 ETS86113.1 - 8.2e-13 47.8 0.3 1.7e-12 46.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Orthoreo_P17 PF07272.6 ETS86113.1 - 0.14 11.9 0.4 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Orthoreovirus P17 protein Peptidase_A4 PF01828.12 ETS86114.1 - 1.1e-74 249.9 8.1 1.3e-74 249.7 5.6 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S66 PF02016.10 ETS86115.1 - 3.9e-50 170.3 0.0 4.7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase FAD_binding_3 PF01494.14 ETS86117.1 - 1.9e-12 46.9 0.0 3.6e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS86117.1 - 0.00043 19.2 0.1 0.0034 16.3 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86117.1 - 0.0063 16.5 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS86117.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 ETS86117.1 - 0.058 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thymidylate_kin PF02223.12 ETS86121.1 - 4.6e-42 143.5 0.0 1.1e-41 142.2 0.0 1.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 ETS86121.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 ETS86121.1 - 0.029 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Nop14 PF04147.7 ETS86123.1 - 5.5 4.7 7.9 8.2 4.1 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family PfkB PF00294.19 ETS86124.1 - 3.2e-14 52.7 0.0 1.2e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GST_N_2 PF13409.1 ETS86126.1 - 5.2e-18 64.8 0.0 9.6e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS86126.1 - 3.4e-05 23.6 0.0 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS86126.1 - 0.00048 20.5 0.0 0.00077 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS86126.1 - 0.0013 18.9 0.0 0.084 13.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 ETS86127.1 - 1.6e-17 63.9 0.2 2.2e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86127.1 - 2.8e-07 30.3 0.1 4.4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS86127.1 - 7.4e-06 25.8 0.0 9.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GTP_cyclohydroI PF01227.17 ETS86128.1 - 2.1e-74 248.7 0.6 2.8e-74 248.2 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I OmpH PF03938.9 ETS86128.1 - 0.0013 18.6 0.5 0.014 15.3 0.3 2.2 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) QueF PF14489.1 ETS86128.1 - 0.0024 17.7 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein DUF3513 PF12026.3 ETS86128.1 - 0.088 12.3 0.7 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) TAFII28 PF04719.9 ETS86129.1 - 8.3e-17 60.7 1.0 2.3e-16 59.3 0.7 1.8 1 1 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 ETS86129.1 - 0.16 12.0 1.4 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cellulase PF00150.13 ETS86130.1 - 1.1e-08 34.6 0.0 2.5e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 ETS86131.1 - 3.1e-32 111.6 37.4 3.8e-32 111.3 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4622 PF15415.1 ETS86133.1 - 0.055 12.2 0.3 0.076 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) Cu-oxidase_2 PF07731.9 ETS86134.1 - 5.3e-41 139.3 8.4 3.5e-39 133.4 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 ETS86134.1 - 1.8e-38 130.8 2.3 1.8e-38 130.8 1.6 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 ETS86134.1 - 9.2e-34 116.6 0.9 4e-32 111.3 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Dioxygenase_C PF00775.16 ETS86135.1 - 4.3e-09 35.8 0.3 1.7e-07 30.6 0.2 2.6 1 1 0 1 1 1 1 Dioxygenase SHOCT PF09851.4 ETS86135.1 - 0.03 13.8 0.3 0.076 12.5 0.2 1.7 1 0 0 1 1 1 0 Short C-terminal domain DUF2217 PF10265.4 ETS86137.1 - 0.05 12.3 4.1 0.077 11.7 2.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PAP1 PF08601.5 ETS86137.1 - 2.7 7.6 12.6 3.6 7.1 8.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 ETS86137.1 - 8.5 4.5 10.5 11 4.1 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_2 PF00891.13 ETS86138.1 - 1.8e-30 105.9 0.0 3e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 ETS86138.1 - 0.00023 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 ETS86138.1 - 0.0055 16.2 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 ETS86138.1 - 0.0056 16.0 0.1 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MTS PF05175.9 ETS86138.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 ETS86138.1 - 0.017 15.6 0.0 0.057 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86138.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.5 ETS86138.1 - 0.05 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 GMC_oxred_N PF00732.14 ETS86139.1 - 3.9e-75 252.7 0.0 5.3e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS86139.1 - 4.6e-37 127.4 0.0 9.7e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS86139.1 - 7.3e-06 25.1 0.0 0.0044 15.9 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS86139.1 - 0.0011 17.9 0.1 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS86139.1 - 0.0059 15.5 0.1 0.87 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 ETS86139.1 - 0.0082 15.2 0.0 0.039 13.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETS86139.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.16 ETS86140.1 - 1.5e-21 76.4 4.2 1.5e-21 76.4 2.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily Polysacc_synt_C PF14667.1 ETS86140.1 - 0.4 10.4 14.1 1.4 8.6 2.6 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Hs1pro-1_N PF07231.7 ETS86141.1 - 0.17 11.4 0.7 0.26 10.8 0.1 1.5 1 1 0 1 1 1 0 Hs1pro-1 N-terminus MFS_1 PF07690.11 ETS86142.1 - 3.2e-34 118.2 24.1 3.2e-34 118.2 16.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 ETS86143.1 - 0.0012 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3283 PF11686.3 ETS86143.1 - 0.095 12.5 0.1 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) DUP PF00674.13 ETS86143.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 DUP family Mito_carr PF00153.22 ETS86144.1 - 7.7e-17 60.7 2.2 0.00014 21.4 0.0 5.3 4 1 0 4 4 4 4 Mitochondrial carrier protein RE_TaqI PF09573.5 ETS86144.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 TaqI restriction endonuclease Fer2 PF00111.22 ETS86145.1 - 2.5e-12 46.3 0.7 4e-12 45.7 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 ETS86146.1 - 1.4e-26 93.1 7.7 1.4e-26 93.1 5.3 2.8 3 0 0 3 3 3 1 Rrp15p Gag_p24 PF00607.15 ETS86146.1 - 0.022 14.3 0.4 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) TauD PF02668.11 ETS86147.1 - 1.2e-57 195.5 0.7 1.7e-57 195.0 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS86147.1 - 0.086 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 CsiD ANT PF03374.9 ETS86147.1 - 0.092 12.8 0.1 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain Glyco_hydro_61 PF03443.9 ETS86148.1 - 1.3e-58 198.3 0.1 2.4e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 ETS86148.1 - 1e-08 34.6 11.3 1e-08 34.6 7.8 3.5 2 1 0 2 2 2 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 ETS86148.1 - 0.0073 16.3 0.8 0.26 11.3 0.0 3.0 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Colipase-like PF15083.1 ETS86150.1 - 0.013 15.3 5.2 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Colipase-like Gamma-thionin PF00304.15 ETS86150.1 - 0.051 13.5 14.8 0.21 11.5 2.7 2.3 2 0 0 2 2 2 0 Gamma-thionin family Colipase PF01114.13 ETS86150.1 - 0.3 10.5 15.4 0.15 11.6 1.7 2.5 2 0 0 2 2 2 0 Colipase, N-terminal domain SseC PF04888.7 ETS86150.1 - 1.4 8.1 6.4 1.9 7.7 4.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Nodulin_late PF07127.6 ETS86150.1 - 1.8 8.7 5.2 9 6.5 0.4 2.3 2 0 0 2 2 2 0 Late nodulin protein ACI44 PF15270.1 ETS86150.1 - 3.8 7.5 9.0 0.54 10.2 1.0 2.1 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Toxin_11 PF07473.6 ETS86150.1 - 4.2 7.3 16.3 5.5 6.9 2.5 2.6 2 0 0 2 2 2 0 Spasmodic peptide gm9a Mannosyl_trans3 PF11051.3 ETS86151.1 - 1.6e-73 247.4 0.0 2.7e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Fungal_trans PF04082.13 ETS86152.1 - 0.0001 21.3 1.3 0.00034 19.5 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.17 ETS86153.1 - 5.8e-11 42.9 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.21 ETS86155.1 - 3.2e-11 42.8 0.0 5.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS86155.1 - 9.6e-07 28.5 0.0 3.2e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PEP_mutase PF13714.1 ETS86155.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase ADH_zinc_N_2 PF13602.1 ETS86155.1 - 0.09 13.6 0.0 0.2 12.5 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pec_lyase_C PF00544.14 ETS86156.1 - 7.1e-46 156.2 2.0 1.5e-45 155.1 1.4 1.5 1 0 0 1 1 1 1 Pectate lyase Sporozoite_P67 PF05642.6 ETS86156.1 - 0.15 9.8 6.3 0.2 9.4 4.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Barwin PF00967.12 ETS86156.1 - 0.58 9.8 4.9 1.7 8.3 3.4 1.8 1 0 0 1 1 1 0 Barwin family 2OG-FeII_Oxy PF03171.15 ETS86157.1 - 3.8e-05 23.9 0.0 7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS86157.1 - 7e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 ETS86159.1 - 8.7e-21 74.0 25.5 1.2e-20 73.5 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 ETS86159.1 - 6.9e-05 21.5 15.1 0.00011 20.8 10.4 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 ETS86159.1 - 0.0034 16.0 10.5 0.0044 15.6 7.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1426 PF07234.6 ETS86159.1 - 0.033 13.9 0.2 0.091 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) DUF1688 PF07958.6 ETS86160.1 - 2.9e-171 569.6 0.0 3.4e-171 569.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.15 ETS86161.1 - 1.2e-28 100.1 4.3 1.2e-28 100.1 3.0 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein DUF3460 PF11943.3 ETS86161.1 - 0.018 15.1 0.2 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) TOM13 PF08219.6 ETS86162.1 - 2.2e-32 110.6 0.0 2.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 ETS86163.1 - 1.6e-26 92.3 0.0 2.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 ETS86163.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 ETS86163.1 - 1.5e-07 30.7 0.7 2.8e-07 29.9 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 ETS86163.1 - 0.05 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1524 PF07510.6 ETS86164.1 - 3.9e-15 55.9 0.1 4.7e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Gtr1_RagA PF04670.7 ETS86165.1 - 7.7e-95 316.4 0.1 9.9e-95 316.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 ETS86165.1 - 2e-07 30.3 0.1 3.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 ETS86165.1 - 2.2e-07 30.3 0.0 4.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 ETS86165.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS86165.1 - 8.3e-05 23.0 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 ETS86165.1 - 0.0013 18.2 2.7 0.0051 16.3 0.1 2.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS86165.1 - 0.0041 17.4 0.5 0.0087 16.3 0.4 1.9 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 ETS86165.1 - 0.0086 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF87 PF01935.12 ETS86165.1 - 0.0096 15.7 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF87 G-alpha PF00503.15 ETS86165.1 - 0.019 13.6 0.4 0.46 9.1 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 ETS86165.1 - 0.035 13.3 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 ETS86166.1 - 1.1e-31 109.4 0.1 1.4e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS86166.1 - 4.4e-21 75.5 0.1 2.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS86166.1 - 1e-06 28.1 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 ETS86166.1 - 5e-05 22.5 0.1 6.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 ETS86166.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 ETS86166.1 - 0.061 11.9 0.2 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 ETS86166.1 - 0.07 11.8 3.4 0.22 10.1 0.0 2.5 1 1 1 3 3 3 0 G-protein alpha subunit DNA_pol_viral_N PF00242.12 ETS86167.1 - 2.6 6.9 14.2 3.2 6.6 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TIP120 PF08623.5 ETS86168.1 - 1.2e-64 216.9 1.9 1.1e-62 210.5 0.0 4.4 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 ETS86168.1 - 5.3e-18 65.0 29.8 3.9e-05 23.8 0.1 10.2 9 3 4 13 13 13 6 HEAT repeats HEAT PF02985.17 ETS86168.1 - 2.1e-16 58.4 17.5 0.19 11.9 0.0 10.7 11 0 0 11 11 9 4 HEAT repeat HEAT_EZ PF13513.1 ETS86168.1 - 1.4e-08 34.9 22.3 1.8 9.1 0.4 11.8 11 3 4 15 15 13 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 ETS86168.1 - 2.6e-06 27.7 0.8 1.6 9.1 0.0 6.5 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETS86168.1 - 8.6e-06 24.3 16.1 0.21 9.8 0.0 6.6 7 1 0 7 7 7 3 Adaptin N terminal region RIX1 PF08167.7 ETS86168.1 - 2.8e-05 23.8 0.5 0.12 12.0 0.0 4.8 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 ETS86168.1 - 0.00073 19.4 8.5 2.1 8.1 0.0 6.5 7 2 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 DUF2457 PF10446.4 ETS86168.1 - 0.00097 17.9 7.8 0.0016 17.2 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 ETS86168.1 - 0.015 13.2 5.7 0.009 14.0 2.4 1.7 2 0 0 2 2 2 0 Nop14-like family FANCI_S2 PF14676.1 ETS86168.1 - 0.025 14.4 2.2 2 8.3 0.0 4.4 4 0 0 4 4 4 0 FANCI solenoid 2 MMS19_C PF12460.3 ETS86168.1 - 0.044 12.5 8.6 11 4.6 0.0 5.1 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal VHS PF00790.14 ETS86168.1 - 0.06 12.9 0.0 2.6 7.6 0.0 3.3 3 0 0 3 3 2 0 VHS domain V-ATPase_H_C PF11698.3 ETS86168.1 - 0.064 13.1 1.9 25 4.7 0.0 4.3 4 0 0 4 4 4 0 V-ATPase subunit H Nucleoplasmin PF03066.10 ETS86168.1 - 0.55 9.7 8.2 1.4 8.4 5.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 ETS86168.1 - 0.56 9.7 8.4 4 7.0 4.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TFIIF_alpha PF05793.7 ETS86168.1 - 0.64 8.3 10.3 1.1 7.5 7.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Arm PF00514.18 ETS86168.1 - 4.9 7.1 6.4 61 3.6 0.0 5.0 7 0 0 7 7 4 0 Armadillo/beta-catenin-like repeat adh_short PF00106.20 ETS86169.1 - 6.9e-09 35.8 0.1 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86169.1 - 3.2e-06 26.9 0.1 5.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS86169.1 - 0.015 15.2 0.1 3.2 7.7 0.1 2.2 2 0 0 2 2 2 0 NADH(P)-binding adh_short_C2 PF13561.1 ETS86169.1 - 0.04 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GCV_H PF01597.14 ETS86170.1 - 1.3e-33 115.2 0.4 1.6e-33 115.0 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 ETS86170.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Porphobil_deam PF01379.15 ETS86171.1 - 3.4e-76 254.9 0.0 4.4e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 ETS86171.1 - 1.9e-18 66.3 0.1 5e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF2953 PF11167.3 ETS86171.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) S-methyl_trans PF02574.11 ETS86172.1 - 1.8e-28 99.7 0.0 6.8e-28 97.8 0.0 1.7 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 ETS86172.1 - 0.23 11.0 1.5 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Fungal_trans_2 PF11951.3 ETS86173.1 - 0.0012 17.4 0.6 0.0015 17.1 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE PF05008.10 ETS86173.1 - 0.12 12.6 0.2 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Epimerase PF01370.16 ETS86174.1 - 2e-12 47.0 0.0 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS86174.1 - 1.3e-08 33.9 0.0 2.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 ETS86174.1 - 2.9e-08 34.0 0.1 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 ETS86174.1 - 2e-06 27.2 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS86174.1 - 2.7e-05 24.2 0.0 6.9e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 ETS86174.1 - 0.00029 19.8 0.1 0.085 11.7 0.0 2.9 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 ETS86174.1 - 0.011 15.6 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 ETS86174.1 - 0.03 13.2 0.1 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 ETS86174.1 - 0.036 12.9 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.17 ETS86174.1 - 0.11 12.9 0.1 0.37 11.3 0.1 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_7 PF00840.15 ETS86175.1 - 2.1e-144 481.1 12.9 2.7e-144 480.7 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Acylphosphatase PF00708.13 ETS86176.1 - 5.1e-27 93.8 0.2 5.6e-27 93.6 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Hep_59 PF07052.6 ETS86177.1 - 3.6e-14 52.9 1.2 3.6e-14 52.9 0.9 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 FAD_binding_3 PF01494.14 ETS86178.1 - 7e-31 107.5 0.1 1.2e-30 106.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS86178.1 - 2.8e-08 33.0 0.1 0.00025 20.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86178.1 - 9.3e-06 25.5 0.2 4.4e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS86178.1 - 2.3e-05 23.4 0.1 0.007 15.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS86178.1 - 3.4e-05 23.0 0.4 0.0068 15.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 ETS86178.1 - 7.3e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS86178.1 - 0.0008 18.5 0.6 0.0016 17.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 ETS86178.1 - 0.00089 19.1 0.1 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS86178.1 - 0.00091 18.1 0.1 0.0017 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS86178.1 - 0.001 18.0 0.8 0.0022 16.9 0.6 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 ETS86178.1 - 0.0017 16.8 0.2 0.028 12.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 ETS86178.1 - 0.012 15.9 0.3 0.09 13.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS86178.1 - 0.022 14.5 0.7 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 ETS86178.1 - 0.045 12.6 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 ETS86178.1 - 0.092 11.3 1.6 0.87 8.1 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 ETS86178.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.2 ETS86179.1 - 7.2e-85 279.4 29.0 4e-17 62.3 0.7 6.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86179.1 - 5.2e-54 177.4 10.7 2.2e-08 33.5 0.0 11.3 11 1 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 ETS86179.1 - 2e-47 158.7 7.6 8.8e-11 42.0 0.2 8.8 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86179.1 - 1.4e-38 126.9 6.8 5.9e-07 29.1 0.0 11.8 12 1 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 ETS86179.1 - 4.5e-38 128.4 4.2 2.3e-09 37.2 0.0 8.8 6 2 3 10 10 10 6 Ankyrin repeats (many copies) 2OG-FeII_Oxy_5 PF13759.1 ETS86179.1 - 0.092 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase GDPD PF03009.12 ETS86180.1 - 2.6e-48 164.7 0.0 4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 ETS86180.1 - 3.6e-29 100.9 0.4 2.4e-11 43.7 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86180.1 - 8.9e-27 91.5 8.8 2.6e-06 26.9 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 ETS86180.1 - 4.5e-22 77.9 1.6 5.7e-08 33.0 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86180.1 - 9.1e-22 76.6 4.9 2.5e-05 24.3 0.0 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86180.1 - 4.1e-19 66.7 0.7 0.01 15.9 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat SPX PF03105.14 ETS86180.1 - 6.4e-11 42.5 0.0 3.4e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 SPX domain MFS_1 PF07690.11 ETS86181.1 - 4.4e-39 134.1 48.5 4.4e-39 134.1 33.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86181.1 - 2.6e-11 42.7 13.4 2.6e-11 42.7 9.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter PAP2_C PF14360.1 ETS86181.1 - 0.12 12.6 2.1 0.25 11.6 0.4 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Aldo_ket_red PF00248.16 ETS86182.1 - 8.8e-47 159.2 0.0 1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PMM PF03332.8 ETS86184.1 - 2e-80 269.5 0.0 2.3e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 ETS86184.1 - 0.00063 19.3 0.0 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.8 ETS86185.1 - 1.5e-13 51.3 0.0 5e-13 49.5 0.0 1.9 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS86185.1 - 8.9e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase COesterase PF00135.23 ETS86187.1 - 7.2e-96 322.0 0.0 9.7e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86187.1 - 0.00075 19.1 1.1 0.004 16.7 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS86187.1 - 0.019 14.7 0.2 0.034 13.8 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family IDO PF01231.13 ETS86188.1 - 2.2e-06 26.3 0.0 3.8e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD-oxidase_C PF02913.14 ETS86189.1 - 8.4e-30 103.8 0.0 1.3e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS86189.1 - 2.4e-27 95.0 0.0 4.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.1 ETS86190.1 - 2.5e-11 43.5 0.0 4.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86190.1 - 2.2e-09 37.6 0.0 7.8e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86190.1 - 6.4e-09 36.1 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86190.1 - 6.6e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86190.1 - 1.7e-06 28.2 0.0 3.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86190.1 - 1.8e-06 28.4 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS86190.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 ETS86190.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 ETS86190.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 ETS86190.1 - 0.00053 19.2 0.1 0.00081 18.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 ETS86190.1 - 0.0049 16.0 0.1 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 ETS86190.1 - 0.0078 15.2 0.0 0.021 13.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 ETS86190.1 - 0.012 14.6 0.0 0.03 13.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 ETS86190.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.6 ETS86190.1 - 0.053 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 ETS86190.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNase_T PF00929.19 ETS86191.1 - 1.5e-13 51.3 0.0 9.7e-13 48.7 0.0 2.2 3 0 0 3 3 3 1 Exonuclease zf-met PF12874.2 ETS86191.1 - 3.7e-06 26.9 2.8 0.019 15.1 0.2 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS86191.1 - 1.2e-05 25.2 4.4 0.019 15.1 0.3 2.8 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 ETS86191.1 - 2.1e-05 24.6 3.7 0.0098 16.1 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS86191.1 - 0.00088 19.4 3.4 0.48 10.8 0.1 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS86191.1 - 0.065 13.1 0.6 0.065 13.1 0.4 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.15 ETS86191.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 3'-5' exonuclease TPT PF03151.11 ETS86192.1 - 5.9e-07 29.2 3.9 5.9e-07 29.2 2.7 1.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family PsiB PF06290.6 ETS86192.1 - 0.03 13.7 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) GalP_UDP_tr_C PF02744.12 ETS86193.1 - 1.6e-33 115.5 0.0 2.5e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 ETS86193.1 - 8.2e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain ABC_tran PF00005.22 ETS86194.1 - 1.7e-43 148.2 0.0 6.3e-21 75.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS86194.1 - 1.9e-36 125.9 34.5 2.7e-25 89.3 9.2 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS86194.1 - 1.2e-10 41.8 0.1 0.2 11.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 ETS86194.1 - 1.4e-10 40.7 0.5 4.6e-05 22.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 ETS86194.1 - 1.4e-09 37.3 0.5 0.00028 19.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 ETS86194.1 - 2.9e-08 33.1 1.6 0.0031 17.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS86194.1 - 4.1e-08 33.4 0.2 0.0062 16.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 ETS86194.1 - 2e-07 30.5 0.2 0.015 14.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 ETS86194.1 - 2.2e-07 30.5 0.1 0.00085 18.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 ETS86194.1 - 3e-07 30.6 0.6 0.002 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 ETS86194.1 - 5.6e-07 30.0 1.8 0.00051 20.4 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 ETS86194.1 - 3.4e-06 26.7 1.2 0.018 14.5 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 ETS86194.1 - 4.6e-06 25.9 0.7 0.015 14.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 ETS86194.1 - 3.5e-05 23.6 0.0 0.4 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 ETS86194.1 - 4.6e-05 23.7 0.3 0.29 11.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS86194.1 - 5.3e-05 24.0 0.6 0.21 12.4 0.2 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS86194.1 - 9.8e-05 21.5 0.6 0.062 12.3 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.18 ETS86194.1 - 0.00031 20.6 0.1 0.34 10.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 ETS86194.1 - 0.00041 20.0 0.9 0.32 10.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.12 ETS86194.1 - 0.00073 19.4 2.6 0.53 10.0 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 ETS86194.1 - 0.0008 18.9 0.5 0.68 9.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 ETS86194.1 - 0.00085 19.0 0.2 0.51 10.0 0.0 2.5 2 0 0 2 2 2 1 NTPase SbcCD_C PF13558.1 ETS86194.1 - 0.0016 18.3 0.1 0.46 10.4 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 ETS86194.1 - 0.0016 18.1 1.4 0.15 11.8 0.3 3.0 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 ETS86194.1 - 0.0019 17.9 0.1 1.1 8.9 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 ETS86194.1 - 0.002 17.8 1.2 1.4 8.5 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 ETS86194.1 - 0.002 17.6 3.6 0.4 10.1 0.2 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 ETS86194.1 - 0.0024 17.7 0.1 1.7 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 ETS86194.1 - 0.0032 17.9 0.4 2.2 8.8 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein Adeno_IVa2 PF02456.10 ETS86194.1 - 0.0032 16.1 0.3 0.14 10.7 0.0 2.6 3 0 0 3 3 3 1 Adenovirus IVa2 protein RNA_helicase PF00910.17 ETS86194.1 - 0.0091 16.1 0.1 5.5 7.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.24 ETS86194.1 - 0.011 15.2 0.1 6.1 6.3 0.0 3.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase DAP3 PF10236.4 ETS86194.1 - 0.011 14.7 0.3 0.91 8.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.24 ETS86194.1 - 0.011 15.8 0.5 5.4 7.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 ETS86194.1 - 0.015 13.9 0.3 1.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 ETS86194.1 - 0.024 14.2 0.1 5.4 6.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 ETS86194.1 - 0.024 14.4 0.6 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Mg_chelatase PF01078.16 ETS86194.1 - 0.053 12.6 0.1 12 4.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.4 ETS86194.1 - 0.063 11.8 5.0 0.48 8.9 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 ETS86194.1 - 0.21 11.2 3.4 10 5.8 0.2 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA12 PF10443.4 ETS86194.1 - 0.22 9.9 0.1 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein Guanylate_kin PF00625.16 ETS86194.1 - 0.24 10.8 1.1 1 8.7 0.1 2.2 2 0 0 2 2 2 0 Guanylate kinase Rad17 PF03215.10 ETS86194.1 - 0.36 9.4 0.3 3.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 ETS86194.1 - 0.43 9.5 0.2 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.1 ETS86194.1 - 0.49 8.7 0.1 8.1 4.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain bZIP_1 PF00170.16 ETS86195.1 - 4.6e-05 23.2 6.5 4.6e-05 23.2 4.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor PAT1 PF09770.4 ETS86195.1 - 0.02 13.1 10.2 0.022 13.0 7.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 ETS86195.1 - 2.8 7.7 9.1 3.8 7.3 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.10 ETS86195.1 - 6.7 6.6 15.3 0.062 13.1 4.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Pyr_redox_3 PF13738.1 ETS86196.1 - 1.9e-24 86.8 0.0 6.1e-23 81.9 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS86196.1 - 2.7e-12 45.7 0.0 2.8e-11 42.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS86196.1 - 1.5e-08 33.9 0.0 1.2e-06 27.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS86196.1 - 5.3e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS86196.1 - 0.00025 20.8 0.4 0.011 15.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding GFO_IDH_MocA PF01408.17 ETS86197.1 - 5.1e-16 59.2 0.1 8.3e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3328 PF11807.3 ETS86198.1 - 2.3e-30 105.9 0.2 2.9e-30 105.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Zn_clus PF00172.13 ETS86200.1 - 6.1e-09 35.6 8.2 1e-08 34.9 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EamA PF00892.15 ETS86201.1 - 4e-16 59.1 26.5 1.1e-13 51.3 2.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family BofA PF07441.6 ETS86201.1 - 0.21 11.5 7.9 4.7 7.2 1.3 2.9 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Patatin PF01734.17 ETS86202.1 - 1.3e-10 41.5 0.1 3.2e-10 40.2 0.0 1.7 2 1 0 2 2 2 1 Patatin-like phospholipase SNF2_N PF00176.18 ETS86203.1 - 1e-58 198.4 0.0 1.6e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS86203.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VMA21 PF09446.5 ETS86204.1 - 2.5e-15 56.1 10.4 3.5e-15 55.6 7.2 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.4 ETS86205.1 - 2.1e-17 63.3 0.2 2.1e-17 63.3 0.2 3.7 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) ABC_membrane PF00664.18 ETS86206.1 - 5.7e-76 255.5 43.1 3.2e-45 154.6 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 ETS86206.1 - 1.4e-65 219.7 0.2 2.8e-32 111.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 ETS86206.1 - 2.2e-11 43.4 8.0 0.00012 21.4 1.9 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 ETS86206.1 - 4.1e-11 43.1 2.9 1.9e-07 31.2 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 ETS86206.1 - 1.2e-10 40.6 0.6 0.00072 18.2 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 ETS86206.1 - 1.5e-10 41.4 0.6 0.0025 17.8 0.2 3.8 2 2 0 3 3 3 2 AAA domain DUF258 PF03193.11 ETS86206.1 - 6.1e-07 28.7 0.1 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS86206.1 - 1.3e-06 27.8 2.2 0.0011 18.3 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 ETS86206.1 - 3.5e-06 27.1 2.1 0.12 12.4 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 ETS86206.1 - 6.3e-06 27.0 0.5 0.038 14.8 0.3 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 ETS86206.1 - 6.9e-06 25.3 0.5 0.031 13.3 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 ETS86206.1 - 1.8e-05 24.3 5.9 0.12 11.9 0.1 4.4 4 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 ETS86206.1 - 6.5e-05 22.4 1.4 0.17 11.2 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 ETS86206.1 - 7e-05 22.5 0.2 0.4 10.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 ETS86206.1 - 0.00024 20.6 0.0 0.41 10.0 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 ETS86206.1 - 0.00029 20.5 0.6 0.11 12.2 0.0 3.5 3 0 0 3 3 2 1 Part of AAA domain SbcCD_C PF13558.1 ETS86206.1 - 0.00041 20.2 1.6 0.52 10.2 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 ETS86206.1 - 0.0019 18.5 0.1 1.2 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 ETS86206.1 - 0.002 18.3 3.5 5.3 7.2 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 ETS86206.1 - 0.0027 17.3 0.0 0.048 13.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS86206.1 - 0.0038 17.1 0.1 4.6 7.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.1 ETS86206.1 - 0.0044 16.8 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 ETS86206.1 - 0.0067 15.8 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 ETS86206.1 - 0.0098 15.3 0.6 0.13 11.6 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 ETS86206.1 - 0.011 15.6 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 ETS86206.1 - 0.019 14.1 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 ETS86206.1 - 0.021 15.1 13.8 2.6 8.2 6.3 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS86206.1 - 0.026 14.7 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase PRK PF00485.13 ETS86206.1 - 0.033 13.7 0.1 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 ETS86206.1 - 0.039 12.6 0.1 0.65 8.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 ETS86206.1 - 0.049 14.1 0.1 12 6.4 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 ETS86206.1 - 0.052 13.2 0.1 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 ETS86206.1 - 0.056 12.2 0.8 2.3 6.9 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain DUF3987 PF13148.1 ETS86206.1 - 0.084 11.4 0.2 0.21 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.12 ETS86206.1 - 0.1 12.3 2.1 1.3 8.8 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF87 Rad17 PF03215.10 ETS86206.1 - 0.12 10.9 0.1 9.8 4.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein G6PD_C PF02781.11 ETS86207.1 - 1.1e-134 447.9 0.0 1.4e-134 447.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 ETS86207.1 - 2.5e-63 213.6 0.0 4.1e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 ETS86207.1 - 0.012 15.7 0.2 0.029 14.5 0.1 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Sulfotransfer_1 PF00685.22 ETS86207.1 - 0.1 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Ribosomal_L35Ae PF01247.13 ETS86208.1 - 4.3e-42 141.8 0.5 4.8e-42 141.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 ETS86208.1 - 0.00015 21.5 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain TIM-br_sig_trns PF09370.5 ETS86209.1 - 4.5e-128 425.9 0.4 5.2e-128 425.7 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 ETS86209.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase UPF0261 PF06792.6 ETS86210.1 - 5e-127 423.7 1.7 6.3e-127 423.3 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Amino_oxidase PF01593.19 ETS86211.1 - 3e-15 56.2 0.0 9.5e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS86211.1 - 8.2e-10 38.5 0.0 2.4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS86211.1 - 2.7e-08 33.0 0.0 3.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS86211.1 - 8.1e-05 22.9 0.2 0.021 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS86211.1 - 0.0026 17.6 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4607 PF15380.1 ETS86211.1 - 0.0079 15.6 1.1 0.91 8.9 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4607) Pyr_redox_3 PF13738.1 ETS86211.1 - 0.02 14.9 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS86211.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 ETS86211.1 - 0.073 12.8 0.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS86211.1 - 0.092 11.3 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 ETS86211.1 - 0.21 9.9 0.1 2.9 6.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-CCCH_2 PF14608.1 ETS86212.1 - 1e-07 31.6 60.1 9.5e-06 25.4 8.3 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 ETS86212.1 - 0.004 17.2 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) GerE PF00196.14 ETS86212.1 - 0.17 11.2 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family BmKX PF09132.5 ETS86212.1 - 0.24 11.2 7.5 4.4 7.2 1.0 2.9 2 0 0 2 2 2 0 BmKX Glyco_hydro_20 PF00728.17 ETS86213.1 - 6.4e-85 285.3 0.0 8e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 ETS86213.1 - 7.1e-16 59.0 0.0 1.7e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 ETS86213.1 - 4.9e-05 23.8 0.2 0.028 14.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 ETS86214.1 - 1.1e-59 202.2 0.0 1.5e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2205 PF10224.4 ETS86215.1 - 5.3e-32 109.2 0.7 7.2e-32 108.7 0.5 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) ApoO PF09769.4 ETS86215.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O Fungal_trans PF04082.13 ETS86216.1 - 4.3e-15 55.2 0.1 1e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3716 PF12511.3 ETS86217.1 - 0.0001 21.8 9.9 0.00021 20.8 6.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3716) adh_short PF00106.20 ETS86218.1 - 7.8e-18 64.9 0.0 9.2e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86218.1 - 7.6e-11 41.9 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86218.1 - 1.2e-08 34.7 0.0 3.3e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS86218.1 - 3e-05 24.0 0.4 7.8e-05 22.7 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 ETS86218.1 - 0.00019 20.5 0.1 0.00051 19.1 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 ETS86218.1 - 0.0073 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 ETS86218.1 - 0.015 14.5 0.1 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 ETS86218.1 - 0.072 13.1 0.2 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NMO PF03060.10 ETS86219.1 - 7.7e-40 137.0 8.1 2.4e-38 132.1 5.6 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 ETS86219.1 - 1.7e-05 23.8 0.3 0.0026 16.7 0.2 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 ETS86219.1 - 0.0038 16.1 0.2 0.0056 15.6 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.13 ETS86219.1 - 0.048 12.4 1.3 0.081 11.7 0.9 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.12 ETS86219.1 - 0.061 12.5 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 PcrB family Peptidase_A4 PF01828.12 ETS86220.1 - 2.4e-19 69.2 5.4 3.1e-19 68.8 3.8 1.2 1 0 0 1 1 1 1 Peptidase A4 family Fungal_trans_2 PF11951.3 ETS86221.1 - 5.4e-37 127.2 1.0 1e-36 126.4 0.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86221.1 - 1.7e-10 40.6 2.1 1.7e-10 40.6 1.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 ETS86222.1 - 1.1e-142 475.6 20.5 1.3e-142 475.3 14.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 ETS86222.1 - 0.0009 19.3 0.2 0.0067 16.5 0.0 2.7 2 0 0 2 2 2 1 Phospholipid methyltransferase adh_short PF00106.20 ETS86223.1 - 8.3e-18 64.8 0.0 2e-17 63.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS86223.1 - 7e-08 32.3 0.1 1.6e-07 31.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 ETS86223.1 - 4.1e-05 23.1 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 ETS86223.1 - 7.3e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CFEM PF05730.6 ETS86224.1 - 0.035 13.9 8.4 0.05 13.4 5.8 1.2 1 0 0 1 1 1 0 CFEM domain LSR PF05624.9 ETS86224.1 - 4.8 6.9 8.5 0.52 10.0 2.3 2.0 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) PLRV_ORF5 PF01690.12 ETS86224.1 - 6.8 5.7 6.1 8.1 5.4 4.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA PF00004.24 ETS86225.1 - 1.6e-15 57.4 0.0 4.3e-15 56.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS86225.1 - 8.1e-05 22.7 0.7 0.022 14.9 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS86225.1 - 0.00025 21.1 0.0 0.00066 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 ETS86225.1 - 0.00074 18.6 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS86225.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS86225.1 - 0.0074 17.0 0.1 0.19 12.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 ETS86225.1 - 0.01 15.5 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 ETS86225.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 ETS86225.1 - 0.052 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETS86225.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Trypan_PARP PF05887.6 ETS86225.1 - 0.37 10.6 2.4 0.65 9.8 1.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1593 PF07632.6 ETS86226.1 - 3.9e-83 278.7 0.1 5.1e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) TFIIB PF00382.14 ETS86227.1 - 1.4e-35 120.9 0.2 2.4e-22 78.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 ETS86227.1 - 4.6e-12 45.0 1.2 7.9e-12 44.2 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 ETS86227.1 - 0.0012 18.7 0.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.1 ETS86227.1 - 0.014 14.5 0.0 6.1 6.1 0.0 3.1 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Adeno_E3_CR2 PF02439.10 ETS86228.1 - 0.0021 17.5 2.0 0.0037 16.7 1.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF485 PF04341.7 ETS86228.1 - 0.096 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 CoA_transf_3 PF02515.12 ETS86229.1 - 7.6e-60 201.4 0.0 1.4e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III COesterase PF00135.23 ETS86230.1 - 7.5e-98 328.5 0.1 9.5e-98 328.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86230.1 - 6.6e-06 25.8 0.4 7.6e-05 22.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold EKR PF10371.4 ETS86230.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function MCR_C PF04609.7 ETS86231.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Sec8_exocyst PF04048.9 ETS86232.1 - 0.013 15.1 1.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain FANCL_C PF11793.3 ETS86233.1 - 0.023 14.6 0.2 0.56 10.2 0.0 2.5 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C2H2_2 PF12756.2 ETS86233.1 - 0.27 11.3 3.4 2.5 8.2 0.2 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 ETS86233.1 - 3.3 8.2 20.7 0.76 10.2 1.0 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger Alpha-amylase PF00128.19 ETS86237.1 - 8.1e-98 327.6 0.0 1.2e-97 327.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DapB_N PF01113.15 ETS86237.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.19 ETS86238.1 - 7.6e-85 285.1 26.1 9.1e-85 284.9 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86238.1 - 1e-22 80.3 41.7 4.9e-20 71.5 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 ETS86239.1 - 4.9e-07 29.5 10.9 8.5e-07 28.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS86239.1 - 2.2e-05 23.4 0.1 3.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.6 ETS86240.1 - 0.00021 21.0 1.2 0.00035 20.3 0.8 1.4 1 0 0 1 1 1 1 CFEM domain NACHT PF05729.7 ETS86242.1 - 1.3e-06 28.2 0.5 4.5e-05 23.1 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 ETS86242.1 - 0.00082 18.9 0.2 0.005 16.3 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 ETS86242.1 - 0.0011 19.0 0.0 0.007 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS86242.1 - 0.01 15.8 0.0 0.093 12.7 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 ETS86242.1 - 0.013 16.3 0.0 0.062 14.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 ETS86242.1 - 0.031 14.0 0.0 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat ABC_tran PF00005.22 ETS86242.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 ETS86242.1 - 0.032 13.0 0.2 0.81 8.4 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain RNA_helicase PF00910.17 ETS86242.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 ETS86242.1 - 0.05 13.1 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 ETS86242.1 - 0.09 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 ETS86243.1 - 4e-10 39.6 0.2 1.6e-08 34.5 0.1 2.1 2 0 0 2 2 2 2 BTB/POZ domain TauD PF02668.11 ETS86244.1 - 5.1e-36 124.6 0.1 7.1e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 ETS86245.1 - 3.5e-27 95.0 24.2 3.5e-27 95.0 16.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS86245.1 - 1e-05 25.1 0.2 4.9e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family Nod_GRP PF07806.6 ETS86245.1 - 0.4 10.3 2.3 1.2 8.7 1.6 1.8 1 0 0 1 1 1 0 Nodule-specific GRP repeat MFS_1 PF07690.11 ETS86246.1 - 2.2e-16 59.5 50.5 1.4e-09 37.2 16.0 4.1 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 ETS86246.1 - 1.8e-10 39.6 14.1 3.1e-10 38.9 9.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LIP PF03583.9 ETS86247.1 - 7.7e-63 212.3 0.0 9.4e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase AAA PF00004.24 ETS86249.1 - 8.5e-16 58.3 0.0 2.3e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 ETS86249.1 - 0.00026 20.5 0.2 0.025 14.0 0.0 2.5 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 ETS86249.1 - 0.0009 19.3 0.4 0.018 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS86249.1 - 0.00099 18.8 0.1 0.0033 17.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 ETS86249.1 - 0.0016 18.4 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 ETS86249.1 - 0.0021 17.7 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS86249.1 - 0.0063 17.3 0.0 0.022 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 ETS86249.1 - 0.015 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 ETS86249.1 - 0.017 14.5 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 ETS86249.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 ETS86249.1 - 0.025 14.4 0.0 0.085 12.7 0.0 1.9 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.1 ETS86249.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GMC_oxred_C PF05199.8 ETS86250.1 - 6.8e-27 94.5 0.0 1.3e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 ETS86250.1 - 2.6e-23 82.6 0.0 1.9e-22 79.8 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS86250.1 - 0.00028 20.8 0.0 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS86250.1 - 0.00061 18.7 0.0 0.64 8.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS86250.1 - 0.002 18.2 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS86250.1 - 0.018 15.0 0.3 0.047 13.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS86250.1 - 0.019 13.8 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS86250.1 - 0.024 13.4 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 ETS86250.1 - 0.52 9.3 2.9 0.68 8.9 0.6 1.9 2 0 0 2 2 2 0 FAD binding domain CFEM PF05730.6 ETS86251.1 - 7.9e-13 48.0 12.3 1.3e-12 47.3 8.5 1.3 1 0 0 1 1 1 1 CFEM domain PEMT PF04191.8 ETS86252.1 - 0.083 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase RTA1 PF04479.8 ETS86253.1 - 2.2e-52 177.7 5.4 3.6e-52 177.1 3.8 1.2 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 ETS86253.1 - 0.61 9.4 8.2 90 2.3 5.7 2.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase Glyco_hydro_3 PF00933.16 ETS86254.1 - 1.7e-85 286.6 0.0 2.4e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS86254.1 - 3.2e-48 164.2 0.0 6.2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS86254.1 - 1.4e-24 85.7 0.0 2.8e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AA_permease PF00324.16 ETS86255.1 - 1.4e-113 379.8 37.6 1.7e-113 379.5 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS86255.1 - 1.5e-30 106.0 42.8 1.9e-30 105.8 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease Pro_racemase PF05544.6 ETS86256.1 - 4.3e-81 272.2 0.0 4.8e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 ETS86256.1 - 0.01 15.0 0.5 0.035 13.3 0.0 1.8 2 0 0 2 2 2 0 Phenazine biosynthesis-like protein HMG_box_2 PF09011.5 ETS86257.1 - 0.053 13.8 0.5 0.1 12.9 0.4 1.4 1 0 0 1 1 1 0 HMG-box domain Aldo_ket_red PF00248.16 ETS86259.1 - 2.9e-42 144.4 0.0 1e-41 142.6 0.0 1.7 2 0 0 2 2 2 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.16 ETS86259.1 - 3.4e-16 59.0 0.0 9.3e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_transf_28 PF03033.15 ETS86260.1 - 6.4e-22 77.8 0.0 1.8e-21 76.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS86260.1 - 1.1e-05 24.2 0.0 1.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase COesterase PF00135.23 ETS86261.1 - 7.8e-81 272.3 0.1 1.4e-80 271.5 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86261.1 - 8.5e-07 28.7 0.1 3.1e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 ETS86261.1 - 4.2e-06 25.6 0.0 7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 ETS86261.1 - 0.02 14.6 0.1 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Amidohydro_1 PF01979.15 ETS86262.1 - 3.6e-14 53.1 0.0 3.6e-09 36.7 0.0 2.6 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 ETS86262.1 - 1e-13 51.9 1.1 2.2e-06 27.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase PD40 PF07676.7 ETS86262.1 - 2.6e-11 42.9 2.8 0.012 15.2 0.0 5.3 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Amidohydro_5 PF13594.1 ETS86262.1 - 1.3e-09 37.7 0.1 3.1e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS86262.1 - 3.1e-05 23.3 0.7 0.022 13.9 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 ETS86263.1 - 3.3e-31 109.1 2.5 4.2e-31 108.8 1.3 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS86263.1 - 8.6e-16 58.7 2.7 1.7e-15 57.7 1.9 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS86263.1 - 2.6e-10 39.9 0.8 6.6e-10 38.6 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS86263.1 - 5.1e-05 22.6 0.4 5.1e-05 22.6 0.3 3.1 3 1 0 3 3 3 2 Amidohydrolase family MFS_1 PF07690.11 ETS86264.1 - 2.5e-31 108.6 25.5 2.5e-31 108.6 17.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.8 ETS86264.1 - 0.058 13.7 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1700 PF08006.6 ETS86264.1 - 3.6 6.8 9.2 0.25 10.6 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) MFS_1 PF07690.11 ETS86265.1 - 5.5e-08 31.9 21.2 5.5e-08 31.9 14.7 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 ETS86267.1 - 7.4e-22 78.4 0.0 1.3e-20 74.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS86267.1 - 1.7e-10 40.3 2.5 4.7e-09 35.6 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 ETS86267.1 - 6.6e-10 39.1 0.0 1.7e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS86267.1 - 1.1e-09 37.0 0.0 9.5e-09 33.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 ETS86267.1 - 1.9e-05 23.9 0.2 0.044 12.8 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 ETS86267.1 - 0.0012 19.2 0.1 0.3 11.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 ETS86267.1 - 0.0014 18.7 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 ETS86267.1 - 0.016 14.1 0.2 0.66 8.8 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.15 ETS86267.1 - 0.076 13.1 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 ETS86267.1 - 0.11 12.5 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS86267.1 - 0.13 11.1 1.2 6.2 5.6 0.2 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS86267.1 - 0.21 11.3 1.7 45 3.7 0.6 3.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding YhfT PF10797.4 ETS86268.1 - 0.013 14.4 0.1 0.024 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function Scytalone_dh PF02982.9 ETS86269.1 - 1.5e-38 131.8 0.1 1.8e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 ETS86269.1 - 2e-09 37.4 0.1 2.7e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 ETS86270.1 - 8.7e-28 97.0 19.8 8.7e-28 97.0 13.7 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86270.1 - 6.3e-12 44.8 25.1 7.5e-11 41.2 6.1 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 ETS86270.1 - 3.6e-05 22.1 3.6 5.7e-05 21.5 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 ETS86270.1 - 0.29 10.9 0.1 0.29 10.9 0.1 4.1 4 1 1 5 5 5 0 MFS_1 like family Tannase PF07519.6 ETS86271.1 - 1.9e-101 340.1 2.5 1.5e-100 337.1 1.7 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS86271.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AHS2 PF02626.10 ETS86272.1 - 2.3e-74 250.1 0.0 3.6e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 ETS86272.1 - 5.1e-56 189.2 0.0 1.1e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS86272.1 - 1.3e-32 112.1 0.0 1.2e-31 109.1 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS86272.1 - 2.1e-29 101.6 0.0 4.1e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 ETS86272.1 - 1.4e-22 80.1 0.0 3.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 ETS86272.1 - 2.8e-13 50.0 0.0 5.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS86272.1 - 5.8e-09 35.1 0.0 8e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 ETS86272.1 - 6.3e-08 32.1 0.7 2.3e-06 27.1 0.7 2.9 2 1 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 ETS86272.1 - 4e-06 26.3 0.0 8.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 ETS86272.1 - 5.7e-05 22.7 0.2 0.019 14.6 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 ETS86272.1 - 0.00061 19.1 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 ETS86272.1 - 0.0038 16.7 0.0 0.01 15.3 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain LamB_YcsF PF03746.11 ETS86273.1 - 2.5e-72 242.8 0.0 3.1e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Aa_trans PF01490.13 ETS86274.1 - 1.2e-18 66.8 33.5 1.5e-18 66.4 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 ETS86274.1 - 0.00012 20.7 28.5 0.00012 20.7 19.8 2.2 1 1 1 2 2 2 1 Amino acid permease Amidase PF01425.16 ETS86275.1 - 2.1e-89 300.4 0.7 2.9e-89 299.9 0.5 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 ETS86276.1 - 4e-29 101.4 57.6 5.4e-17 61.5 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS86276.1 - 0.00097 17.6 32.7 0.03 12.7 11.2 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein DUF3018 PF11455.3 ETS86277.1 - 0.08 12.8 0.2 1.7 8.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3018) Ferritin_2 PF13668.1 ETS86278.1 - 8.1e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain COesterase PF00135.23 ETS86279.1 - 1e-74 252.1 2.1 3.4e-63 214.1 0.9 2.7 1 1 2 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86279.1 - 5e-05 22.9 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS86279.1 - 0.059 13.1 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ldh_1_N PF00056.18 ETS86280.1 - 2.3e-42 144.1 0.1 3.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 ETS86280.1 - 1.5e-37 129.0 0.0 2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 ETS86280.1 - 2.5e-05 23.1 0.0 3.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 ETS86280.1 - 0.0058 15.9 0.3 2.6 7.3 0.1 2.2 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 ETS86280.1 - 0.055 12.5 0.1 0.21 10.6 0.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 ETS86280.1 - 0.097 12.6 0.4 0.22 11.5 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 ETS86281.1 - 7.8e-52 174.9 0.0 1.1e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS86281.1 - 1.8e-20 72.7 0.0 2.3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS86281.1 - 0.00017 21.4 0.1 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 ETS86282.1 - 4e-93 312.4 20.8 4.6e-93 312.2 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86282.1 - 1.7e-23 82.9 20.7 1.7e-23 82.9 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 ETS86282.1 - 6.8e-06 24.5 2.6 1.3e-05 23.6 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3816 PF12822.2 ETS86283.1 - 0.3 10.9 7.5 0.81 9.5 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) SPC12 PF06645.8 ETS86283.1 - 0.63 9.8 4.7 0.22 11.3 0.3 2.4 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Zn_clus PF00172.13 ETS86284.1 - 9.3e-08 31.8 7.2 9.3e-08 31.8 5.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS86284.1 - 0.0057 15.5 0.0 0.0091 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 ETS86285.1 - 1e-25 90.1 0.0 1.7e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86285.1 - 5e-11 42.3 12.4 9e-11 41.5 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_trans PF02705.11 ETS86286.1 - 1.9e-180 600.7 19.1 2.2e-180 600.5 13.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF485 PF04341.7 ETS86286.1 - 0.16 11.6 5.4 9.7 5.9 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Pkinase PF00069.20 ETS86287.1 - 7.1e-58 195.7 0.0 9.3e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86287.1 - 3.6e-27 95.0 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS86287.1 - 0.00039 20.2 0.0 0.0015 18.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS86287.1 - 0.00055 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 ETS86287.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 ETS86287.1 - 0.0071 15.4 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 ETS86287.1 - 0.0084 15.1 0.0 0.021 13.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like TrkH PF02386.11 ETS86288.1 - 8.3e-112 373.2 9.6 1.5e-108 362.5 2.6 2.1 2 0 0 2 2 2 2 Cation transport protein Acyl_transf_3 PF01757.17 ETS86289.1 - 3.3e-15 55.7 22.9 6.2e-15 54.8 15.9 1.7 1 1 0 1 1 1 1 Acyltransferase family E1-E2_ATPase PF00122.15 ETS86290.1 - 1.6e-66 223.6 2.4 1.6e-66 223.6 1.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS86290.1 - 3.3e-33 114.7 7.4 3.3e-33 114.7 5.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS86290.1 - 2.3e-30 106.6 0.1 5.1e-26 92.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS86290.1 - 1.3e-17 62.9 0.1 3.9e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS86290.1 - 2.6e-17 63.6 0.0 6.2e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS86290.1 - 2.2e-16 59.5 0.0 5.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS86290.1 - 0.0013 18.3 0.1 0.0062 16.1 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HET PF06985.6 ETS86291.1 - 3.9e-24 85.3 0.1 9.4e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 ETS86292.1 - 0.00087 18.9 0.3 0.0025 17.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 ETS86292.1 - 0.4 10.3 8.1 4 7.1 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) GATase PF00117.23 ETS86293.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Lactonase PF10282.4 ETS86295.1 - 2.6e-09 36.6 0.6 0.055 12.5 0.0 3.4 2 2 1 3 3 3 3 Lactonase, 7-bladed beta-propeller NHL PF01436.16 ETS86295.1 - 0.0019 18.0 0.0 1.6 8.7 0.0 3.8 4 0 0 4 4 4 2 NHL repeat Cu-oxidase PF00394.17 ETS86295.1 - 0.0045 16.8 0.2 0.0074 16.1 0.1 1.3 1 0 0 1 1 1 1 Multicopper oxidase DUF1517 PF07466.6 ETS86298.1 - 0.007 15.3 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) MARVEL PF01284.18 ETS86299.1 - 2e-09 37.4 6.9 2.7e-09 36.9 4.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.14 ETS86299.1 - 0.0034 16.8 1.3 0.0047 16.4 0.7 1.5 1 1 0 1 1 1 1 VIT family UNC-50 PF05216.8 ETS86299.1 - 0.026 13.7 1.6 0.036 13.2 0.2 1.7 1 1 1 2 2 2 0 UNC-50 family O-antigen_lig PF13425.1 ETS86299.1 - 0.1 12.5 3.5 0.15 12.0 1.5 1.7 1 1 1 2 2 2 0 O-antigen ligase like membrane protein PAN_1 PF00024.21 ETS86300.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 ETS86300.1 - 0.0018 17.5 0.1 0.0048 16.1 0.1 1.7 1 1 0 1 1 1 1 Fringe-like PAN_3 PF08277.7 ETS86300.1 - 0.011 15.3 0.5 0.019 14.5 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.16 ETS86300.1 - 0.036 13.6 0.1 0.097 12.2 0.1 1.7 1 0 0 1 1 1 0 Galactosyltransferase RNase_H PF00075.19 ETS86302.1 - 4.7e-14 52.8 0.0 7.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 ETS86302.1 - 0.0044 16.7 0.0 0.094 12.5 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like Alpha-L-AF_C PF06964.7 ETS86304.1 - 2.7e-30 105.4 0.0 4.3e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 ETS86304.1 - 0.007 16.3 0.5 0.028 14.4 0.4 2.1 1 1 0 1 1 1 1 Carbohydrate binding domain Aldo_ket_red PF00248.16 ETS86305.1 - 1.6e-65 220.7 0.0 1.8e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.6 ETS86306.1 - 7.4e-09 34.9 0.1 0.00017 20.9 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 ETS86306.1 - 0.00025 20.7 0.0 0.56 9.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 ETS86306.1 - 0.0012 18.2 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 ETS86306.1 - 0.0027 17.1 0.0 0.63 9.4 0.0 2.4 2 0 0 2 2 2 2 Cupin EutQ PF06249.7 ETS86306.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 ETS86306.1 - 0.043 13.5 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain Nitroreductase PF00881.19 ETS86307.1 - 4.7e-30 104.5 0.0 6.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF3099 PF11298.3 ETS86308.1 - 0.15 11.8 2.7 0.48 10.2 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) ArsB PF02040.10 ETS86309.1 - 1.5e-17 63.6 20.9 1.3e-12 47.4 5.8 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF1212 PF06738.7 ETS86310.1 - 1.8e-48 164.6 19.2 2.9e-46 157.3 2.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 ETS86310.1 - 1.5e-21 76.6 14.1 1.5e-21 76.6 9.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) ThuA PF06283.6 ETS86310.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation MAP65_ASE1 PF03999.7 ETS86310.1 - 3.4 6.1 4.1 5.4 5.4 2.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SNF2_N PF00176.18 ETS86311.1 - 1.2e-57 195.0 0.0 1.9e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain APH PF01636.18 ETS86311.1 - 1.8e-11 44.2 0.7 5.4e-11 42.6 0.5 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Helicase_C PF00271.26 ETS86311.1 - 5.2e-10 39.0 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EcKinase PF02958.15 ETS86311.1 - 2.8e-07 29.9 0.0 8.1e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 ETS86311.1 - 1e-05 25.2 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase ResIII PF04851.10 ETS86311.1 - 0.0011 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1679 PF07914.6 ETS86311.1 - 0.033 12.8 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 ETS86311.1 - 0.037 13.0 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase NACHT PF05729.7 ETS86312.1 - 7e-06 25.8 2.0 1.7e-05 24.5 0.3 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS86312.1 - 0.00014 21.9 10.4 0.00017 21.6 0.3 3.8 3 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 ETS86312.1 - 0.0059 16.7 0.6 1.6 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain UBN2 PF14223.1 ETS86312.1 - 0.0087 15.8 1.0 1.2 8.9 0.1 3.8 4 0 0 4 4 4 1 gag-polypeptide of LTR copia-type AAA PF00004.24 ETS86312.1 - 0.011 15.9 1.2 3.2 7.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 ETS86312.1 - 0.013 14.3 0.0 0.039 12.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain p450 PF00067.17 ETS86313.1 - 1.4e-25 89.7 0.0 5.2e-24 84.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 EmrE PF13536.1 ETS86313.1 - 0.033 14.3 0.2 0.096 12.8 0.1 1.7 1 0 0 1 1 1 0 Multidrug resistance efflux transporter AMP-binding PF00501.23 ETS86314.1 - 2.9e-60 203.8 0.0 3.8e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS86314.1 - 3.3e-13 50.3 0.0 7.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 ETS86315.1 - 6.8e-72 241.9 0.0 8.3e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 ETS86315.1 - 0.049 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3176 PF11374.3 ETS86316.1 - 4.3e-32 110.2 0.1 1.2e-31 108.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) p450 PF00067.17 ETS86318.1 - 6.8e-30 103.9 0.0 7.7e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LcrG PF07216.7 ETS86318.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 LcrG protein zf-C2H2_4 PF13894.1 ETS86319.1 - 1e-05 25.4 8.5 0.011 16.0 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS86319.1 - 0.0002 21.5 8.1 0.026 14.8 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Daxx PF03344.10 ETS86319.1 - 0.00044 18.8 17.6 0.00052 18.6 12.2 1.1 1 0 0 1 1 1 1 Daxx Family zf-H2C2_2 PF13465.1 ETS86319.1 - 0.027 14.7 1.0 0.052 13.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 ETS86319.1 - 0.12 12.3 1.2 0.74 9.8 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 ETS86319.1 - 1.6 8.7 4.6 2.1 8.3 1.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Lin-8 PF03353.10 ETS86319.1 - 9.9 5.3 11.1 15 4.7 7.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ABC_tran PF00005.22 ETS86320.1 - 3.5e-53 179.5 0.0 1.7e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS86320.1 - 9e-29 100.7 19.3 6.6e-26 91.3 0.3 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS86320.1 - 9.6e-11 41.3 0.3 0.0067 15.6 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS86320.1 - 3.7e-08 33.6 0.0 0.11 12.3 0.0 4.2 2 2 1 4 4 4 2 AAA domain AAA_33 PF13671.1 ETS86320.1 - 1.8e-07 31.1 0.0 0.0052 16.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS86320.1 - 3.5e-07 30.3 0.1 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 ETS86320.1 - 4.3e-07 29.2 0.1 0.0062 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 ETS86320.1 - 9.7e-07 28.2 0.2 0.013 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS86320.1 - 1.8e-06 28.7 0.0 0.0091 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 ETS86320.1 - 2.2e-06 27.6 0.7 0.056 13.2 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 ETS86320.1 - 1.1e-05 25.5 0.3 0.18 11.9 0.0 3.0 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 ETS86320.1 - 1.7e-05 24.7 0.4 0.032 14.1 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 ETS86320.1 - 2.7e-05 23.7 0.1 0.033 13.6 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 ETS86320.1 - 2.8e-05 24.4 0.1 0.02 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ETS86320.1 - 3.2e-05 24.3 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS86320.1 - 7e-05 21.8 0.1 0.069 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 ETS86320.1 - 7.7e-05 22.4 0.7 0.028 14.1 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 ETS86320.1 - 8.2e-05 23.0 0.0 0.28 11.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 ETS86320.1 - 0.00012 21.1 0.0 0.026 13.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS86320.1 - 0.00013 21.5 0.1 0.57 9.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 ETS86320.1 - 0.00026 20.4 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 ETS86320.1 - 0.00028 20.5 0.3 0.19 11.3 0.1 2.8 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 ETS86320.1 - 0.00039 20.2 0.5 0.047 13.5 0.1 2.7 2 0 0 2 2 2 1 Dynamin family Adeno_IVa2 PF02456.10 ETS86320.1 - 0.00098 17.8 0.1 0.072 11.7 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein RNA_helicase PF00910.17 ETS86320.1 - 0.0016 18.5 0.0 3.9 7.7 0.0 3.4 3 0 0 3 3 2 0 RNA helicase SbcCD_C PF13558.1 ETS86320.1 - 0.0032 17.3 0.1 0.3 11.0 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 ETS86320.1 - 0.0043 16.7 0.3 1.7 8.2 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 ETS86320.1 - 0.0044 16.9 0.1 1.7 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.13 ETS86320.1 - 0.0048 16.4 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.14 ETS86320.1 - 0.01 15.3 0.9 0.54 9.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 ETS86320.1 - 0.021 13.5 0.3 2.2 6.9 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 ETS86320.1 - 0.026 14.2 0.1 5.9 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 ETS86320.1 - 0.036 13.6 0.4 6.4 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 ETS86320.1 - 0.05 12.4 0.3 1.8 7.3 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.12 ETS86320.1 - 0.055 13.0 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 ETS86320.1 - 0.09 11.7 0.8 10 5.0 0.0 3.1 3 0 0 3 3 3 0 Septin GTP_EFTU PF00009.22 ETS86320.1 - 0.098 12.0 0.0 12 5.2 0.0 2.6 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 ETS86320.1 - 0.1 12.5 0.3 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS86320.1 - 0.12 11.9 0.1 15 5.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 ETS86320.1 - 0.17 12.1 0.3 6 7.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 ETS86320.1 - 0.18 11.5 0.4 16 5.1 0.0 2.4 2 0 0 2 2 2 0 NTPase DAP3 PF10236.4 ETS86320.1 - 0.28 10.0 0.9 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Acyl_transf_1 PF00698.16 ETS86321.1 - 8.9e-66 222.3 0.6 3e-65 220.6 0.3 1.9 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 ETS86321.1 - 3.8e-58 196.1 2.0 6.3e-58 195.4 0.2 2.4 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 ETS86321.1 - 1.1e-56 192.1 0.1 2.4e-56 191.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 ETS86321.1 - 2.9e-55 187.5 0.1 5.2e-55 186.6 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 ETS86321.1 - 1.1e-43 148.9 1.2 3.6e-43 147.3 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS86321.1 - 4.5e-29 100.7 0.1 1.1e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS86321.1 - 1.2e-18 67.3 0.0 4.5e-18 65.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS86321.1 - 1.7e-15 56.6 0.1 4.7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 ETS86321.1 - 4.3e-12 45.8 0.0 1.8e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86321.1 - 5.8e-12 45.6 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 ETS86321.1 - 1.8e-09 38.5 0.0 9e-09 36.3 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 ETS86321.1 - 6e-09 36.0 0.3 1.6e-08 34.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 ETS86321.1 - 1.6e-08 34.8 0.0 5.6e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86321.1 - 1.9e-08 34.8 0.0 5.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 ETS86321.1 - 1.6e-06 27.8 1.1 4.3e-06 26.4 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 ETS86321.1 - 1.5e-05 25.2 0.0 7.1e-05 23.1 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86321.1 - 0.00026 21.0 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 ETS86321.1 - 0.00078 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase 3Beta_HSD PF01073.14 ETS86321.1 - 0.0028 16.4 0.0 0.0052 15.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 ETS86321.1 - 0.0044 16.1 0.0 0.038 13.0 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 ETS86321.1 - 0.024 15.4 0.0 0.12 13.2 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.15 ETS86321.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 ETS86321.1 - 0.11 11.9 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DSPc PF00782.15 ETS86321.1 - 0.17 11.4 0.0 0.48 9.9 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain p450 PF00067.17 ETS86322.1 - 1.7e-61 208.1 0.0 2.9e-61 207.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 ETS86323.1 - 1.2e-16 60.8 0.0 3.1e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS86323.1 - 4.3e-13 49.2 0.0 6.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS86323.1 - 8.6e-13 48.6 1.5 1e-12 48.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS86323.1 - 3.4e-07 29.7 0.0 0.00036 19.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 ETS86323.1 - 1.2e-06 27.6 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 ETS86323.1 - 0.00019 20.3 0.0 0.00097 17.9 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 ETS86323.1 - 0.0012 18.3 0.0 0.27 10.6 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 ETS86323.1 - 0.042 13.3 0.0 0.094 12.2 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.23 ETS86324.1 - 0 1352.9 4.5 1.7e-85 286.9 0.0 5.5 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 ETS86324.1 - 1.7e-193 641.1 8.0 1.5e-35 122.5 0.0 6.5 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 ETS86324.1 - 2e-61 204.1 6.0 2.8e-10 40.3 0.0 7.1 7 0 0 7 7 7 6 Phosphopantetheine attachment site AATase PF07247.7 ETS86324.1 - 4.4e-05 22.2 0.1 7.6 4.9 0.0 4.8 5 0 0 5 5 5 3 Alcohol acetyltransferase Transferase PF02458.10 ETS86324.1 - 0.14 10.5 0.1 35 2.6 0.0 3.6 4 0 0 4 4 4 0 Transferase family HLH PF00010.21 ETS86325.1 - 4.4e-06 26.2 0.1 1.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Mucin PF01456.12 ETS86325.1 - 1.8 8.3 11.9 1.2 8.9 5.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein HLH PF00010.21 ETS86326.1 - 1.9e-07 30.6 0.1 1.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Helicase_C_4 PF13871.1 ETS86326.1 - 0.054 12.9 0.2 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 Helicase_C-like DUF3209 PF11483.3 ETS86326.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF3292 PF11696.3 ETS86326.1 - 1.3 6.7 4.9 1.8 6.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Aminotran_1_2 PF00155.16 ETS86327.1 - 4.5e-07 29.1 0.0 4.7e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 ETS86327.1 - 0.052 12.6 0.0 0.052 12.6 0.0 1.0 1 0 0 1 1 1 0 Beta-eliminating lyase Methyltransf_11 PF08241.7 ETS86328.1 - 1.1e-10 41.8 0.0 2.9e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86328.1 - 6.6e-09 35.5 0.0 9.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86328.1 - 1.1e-07 32.2 0.0 4.2e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS86328.1 - 1.6e-07 30.7 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 ETS86328.1 - 2.9e-05 24.6 0.0 6.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86328.1 - 4.1e-05 23.3 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86328.1 - 6.7e-05 23.1 0.0 0.00019 21.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86328.1 - 0.00023 21.2 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.9 ETS86328.1 - 0.00023 21.1 0.0 0.00084 19.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.9 ETS86328.1 - 0.0037 16.6 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF3314 PF11771.3 ETS86328.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Aminotran_3 PF00202.16 ETS86329.1 - 7.2e-83 278.2 0.0 8.5e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aspzincin_M35 PF14521.1 ETS86330.1 - 1.2e-19 71.2 0.2 1.6e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase E1-E2_ATPase PF00122.15 ETS86331.1 - 3.9e-49 166.7 4.5 3.9e-49 166.7 3.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETS86331.1 - 1.3e-22 81.2 0.1 2.2e-22 80.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS86331.1 - 2.3e-13 50.7 0.1 6.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS86331.1 - 4.6e-05 23.1 0.4 0.0089 15.6 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 ETS86331.1 - 0.00053 20.0 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Flavin_Reduct PF01613.13 ETS86332.1 - 1.4e-24 86.6 0.0 2.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_18 PF00704.23 ETS86333.1 - 2e-98 330.0 12.7 2.3e-98 329.7 8.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Orthopox_A36R PF05950.6 ETS86333.1 - 0.072 13.0 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Orthopoxvirus A36R protein TPR_12 PF13424.1 ETS86336.1 - 3.5e-36 123.0 14.3 2.3e-15 56.3 0.6 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETS86336.1 - 6.1e-22 76.8 17.5 7.1e-07 28.9 0.1 6.9 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS86336.1 - 4e-11 41.8 7.2 0.12 12.2 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS86336.1 - 5.7e-10 38.6 6.3 6.3e-05 22.5 0.7 4.9 2 1 3 5 5 5 4 TPR repeat NB-ARC PF00931.17 ETS86336.1 - 7.3e-10 38.1 0.1 1.3e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 ETS86336.1 - 2.4e-09 36.4 0.9 0.068 12.8 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 ETS86336.1 - 3.2e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 ETS86336.1 - 7.6e-07 29.2 10.5 0.2 12.4 0.0 8.0 7 2 3 10 10 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 ETS86336.1 - 1.3e-06 28.8 1.9 0.8 10.4 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat NACHT PF05729.7 ETS86336.1 - 2.3e-06 27.3 0.0 7.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 ETS86336.1 - 4.1e-06 26.1 2.9 0.2 11.4 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 ETS86336.1 - 4.3e-06 26.2 13.3 0.035 14.0 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS86336.1 - 1.4e-05 25.3 12.9 0.0029 17.9 0.2 6.1 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS86336.1 - 2.1e-05 24.3 0.1 6 7.3 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS86336.1 - 2.4e-05 24.4 8.5 1 9.9 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 ETS86336.1 - 0.00041 20.2 0.2 0.0018 18.2 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_9 PF13371.1 ETS86336.1 - 0.00044 20.0 5.0 0.41 10.5 0.0 4.8 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS86336.1 - 0.00064 19.8 2.8 1.2 9.7 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat IstB_IS21 PF01695.12 ETS86336.1 - 0.00083 18.8 0.0 0.0029 17.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Apc3 PF12895.2 ETS86336.1 - 0.0015 18.6 1.1 0.071 13.2 0.1 3.4 4 0 0 4 4 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 ETS86336.1 - 0.0033 17.2 0.0 1 9.4 0.0 3.8 4 0 0 4 4 4 1 PPR repeat PGAP1 PF07819.8 ETS86336.1 - 0.0076 15.8 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 ETS86336.1 - 0.02 14.6 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family XH PF03469.9 ETS86336.1 - 0.021 14.4 1.0 0.06 13.0 0.7 1.7 1 0 0 1 1 1 0 XH domain AAA_16 PF13191.1 ETS86336.1 - 0.032 14.2 0.3 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.21 ETS86336.1 - 0.048 13.1 0.2 0.11 11.9 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain MIT PF04212.13 ETS86336.1 - 0.065 13.1 0.1 0.065 13.1 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ank_2 PF12796.2 ETS86337.1 - 1.2e-40 137.7 15.3 2.3e-07 31.0 0.0 9.3 6 2 3 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86337.1 - 3.4e-17 61.3 15.4 0.0033 17.1 0.0 13.9 18 0 0 18 18 18 3 Ankyrin repeat Ank_4 PF13637.1 ETS86337.1 - 4.2e-15 55.7 2.4 1.5e-05 25.3 0.0 7.6 9 1 1 10 10 10 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86337.1 - 1e-14 53.1 14.8 0.31 11.4 0.0 14.3 17 2 1 18 18 18 3 Ankyrin repeat Ank_5 PF13857.1 ETS86337.1 - 1.9e-08 34.2 9.0 0.012 15.8 0.0 9.1 9 2 2 11 11 11 2 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.3 ETS86339.1 - 4.1e-06 25.6 0.4 4.1e-06 25.6 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 ETS86340.1 - 0.01 14.9 0.1 0.017 14.2 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86340.1 - 0.07 12.1 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase KdgT PF03812.8 ETS86340.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease HET PF06985.6 ETS86341.1 - 2.7e-22 79.4 0.0 4.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PA14_2 PF10528.4 ETS86342.1 - 1.2e-25 89.6 0.1 4.2e-25 87.9 0.1 1.9 1 0 0 1 1 1 1 GLEYA domain VPS9 PF02204.13 ETS86344.1 - 7.3e-18 64.5 0.0 1.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 ETS86344.1 - 5.7e-15 55.0 3.7 1.6e-10 40.8 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS86344.1 - 3.4e-12 46.5 0.1 6.8e-08 32.7 0.0 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS86344.1 - 2.6e-09 37.3 0.2 0.00053 20.4 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86344.1 - 4.2e-08 32.6 0.7 0.58 10.5 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 ETS86344.1 - 1.8e-07 30.5 3.5 0.0062 16.3 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeat PX PF00787.19 ETS86344.1 - 0.0025 17.5 0.1 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 PX domain Methyltransf_11 PF08241.7 ETS86345.1 - 1.2e-22 80.1 0.0 2.6e-22 79.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86345.1 - 1.4e-16 60.4 0.0 2.4e-16 59.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86345.1 - 2.5e-16 60.2 0.0 8.4e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86345.1 - 1.4e-15 57.4 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86345.1 - 8.6e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86345.1 - 3.7e-13 49.7 0.0 8.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86345.1 - 1.4e-11 44.4 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS86345.1 - 5.1e-08 32.4 0.0 7.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 ETS86345.1 - 1.2e-06 27.8 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 ETS86345.1 - 1.4e-06 27.2 0.0 1.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 ETS86345.1 - 3.3e-06 26.4 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 ETS86345.1 - 9.8e-06 24.8 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 ETS86345.1 - 1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 ETS86345.1 - 0.00019 20.9 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 ETS86345.1 - 0.00021 20.4 0.0 0.00092 18.3 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 ETS86345.1 - 0.0015 18.5 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 ETS86345.1 - 0.0017 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 ETS86345.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 ETS86345.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW H_PPase PF03030.11 ETS86346.1 - 0.11 10.7 0.1 0.15 10.2 0.1 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF2306 PF10067.4 ETS86346.1 - 7.7 6.6 8.1 0.33 11.0 0.5 2.4 2 1 2 4 4 4 0 Predicted membrane protein (DUF2306) HATPase_c PF02518.21 ETS86347.1 - 1.3e-22 79.6 0.2 2.5e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS86347.1 - 8.3e-22 77.3 0.1 2e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 ETS86347.1 - 3.1e-12 46.3 0.0 1e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 ETS86347.1 - 0.094 12.3 0.9 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CorA PF01544.13 ETS86348.1 - 2e-12 46.7 0.1 3.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 ETS86349.1 - 1.3e-07 30.9 0.5 1.3e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein adh_short PF00106.20 ETS86351.1 - 4.6e-27 94.9 0.7 7.2e-27 94.3 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86351.1 - 1.6e-15 57.5 0.0 2.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86351.1 - 8.1e-10 38.6 0.1 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86351.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS86351.1 - 0.0053 16.5 0.1 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 ETS86351.1 - 0.0058 16.6 0.1 0.038 13.9 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding Glyco_hydro_43 PF04616.9 ETS86352.1 - 3.2e-66 223.3 0.0 4.5e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 ETS86353.1 - 1.4e-56 192.0 28.4 1.7e-56 191.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86353.1 - 1.9e-12 46.5 39.4 1.9e-12 46.5 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3094 PF11293.3 ETS86353.1 - 0.15 11.5 0.5 0.37 10.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Macoilin PF09726.4 ETS86355.1 - 7.2 4.7 21.6 9.4 4.3 14.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Response_reg PF00072.19 ETS86356.1 - 2.1e-19 69.5 0.1 8e-18 64.4 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 ETS86356.1 - 4e-19 68.3 0.0 8.1e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 ETS86356.1 - 1.6e-13 50.4 0.4 4e-13 49.1 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 ETS86356.1 - 0.003 17.6 0.6 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 GAF domain NnrU PF07298.6 ETS86357.1 - 3.4 7.0 10.6 42 3.4 6.6 3.0 2 1 0 2 2 2 0 NnrU protein Zn_clus PF00172.13 ETS86358.1 - 9.3e-09 35.0 9.8 9.3e-09 35.0 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS86358.1 - 0.0027 16.3 1.2 0.0045 15.6 0.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 ETS86359.1 - 1e-61 209.2 0.0 1.5e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86359.1 - 4e-07 29.8 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold p450 PF00067.17 ETS86360.1 - 3.3e-67 226.9 0.0 4.3e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 ETS86361.1 - 2e-18 66.2 5.3 3.1e-18 65.6 3.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS86361.1 - 1.5e-09 37.6 0.5 4.2e-09 36.1 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 ETS86361.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Zn_clus PF00172.13 ETS86362.1 - 8.5e-09 35.1 7.1 1.5e-08 34.3 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS86362.1 - 0.06 11.9 0.3 0.094 11.2 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Adenylsucc_synt PF00709.16 ETS86363.1 - 1.1e-130 436.1 0.5 1e-78 264.9 0.2 2.9 1 1 0 2 2 2 2 Adenylosuccinate synthetase zf-C2H2_4 PF13894.1 ETS86364.1 - 2.4e-05 24.3 28.3 0.058 13.7 0.3 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger bZIP_1 PF00170.16 ETS86364.1 - 0.00026 20.8 4.3 0.0008 19.3 3.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor zf-C2H2 PF00096.21 ETS86364.1 - 0.0035 17.5 1.4 0.0035 17.5 0.9 5.1 5 0 0 5 5 5 1 Zinc finger, C2H2 type bZIP_2 PF07716.10 ETS86364.1 - 0.0036 17.1 3.9 0.0097 15.7 2.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Oxysterol_BP PF01237.13 ETS86366.1 - 1.5e-87 293.4 0.0 1.7e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Asn_synthase PF00733.16 ETS86367.1 - 3.1e-56 190.7 0.0 4.2e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 ETS86367.1 - 3.3e-07 30.0 0.0 6.1e-06 25.9 0.0 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 ETS86367.1 - 0.00019 21.3 0.0 0.0016 18.4 0.0 2.4 3 0 0 3 3 3 1 Glutamine amidotransferase domain AMP-binding PF00501.23 ETS86368.1 - 6.7e-70 235.5 0.0 8e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS86368.1 - 5.6e-14 52.8 0.3 1.1e-13 51.9 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NOA36 PF06524.7 ETS86369.1 - 0.3 10.2 7.6 0.4 9.9 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.11 ETS86370.1 - 3.1e-47 160.9 48.8 8.4e-46 156.2 31.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.4 ETS86370.1 - 0.0051 16.7 1.0 0.06 13.3 1.2 2.2 2 0 0 2 2 2 1 Transmembrane protein 188 PepSY_TM_2 PF13703.1 ETS86370.1 - 0.083 13.0 0.3 0.083 13.0 0.2 4.2 3 1 1 4 4 4 0 PepSY-associated TM helix AlaDh_PNT_N PF05222.10 ETS86371.1 - 8.3e-27 93.8 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 ETS86371.1 - 1.1e-07 31.5 0.0 4.7e-05 23.0 0.0 2.3 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DEC-1_N PF04625.8 ETS86371.1 - 0.13 10.9 0.2 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1996 PF09362.5 ETS86372.1 - 5.9e-83 278.1 3.9 7.1e-83 277.8 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MbtH PF03621.8 ETS86372.1 - 0.11 11.8 0.3 0.72 9.2 0.1 2.2 2 0 0 2 2 2 0 MbtH-like protein RelA_SpoT PF04607.12 ETS86373.1 - 7.6e-19 67.8 1.9 4.6e-18 65.3 0.2 2.3 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins HET PF06985.6 ETS86374.1 - 3.3e-34 118.0 1.8 6e-34 117.1 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M20 PF01546.23 ETS86375.1 - 1.7e-21 76.6 0.1 2.4e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS86375.1 - 1.1e-17 63.7 0.0 1.9e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 ETS86375.1 - 0.00017 21.3 0.1 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Epimerase PF01370.16 ETS86376.1 - 2e-23 83.0 0.0 2.7e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS86376.1 - 1.3e-11 43.7 0.0 1.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS86376.1 - 9.2e-11 41.1 0.0 1.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS86376.1 - 7.3e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 ETS86376.1 - 1.7e-07 30.3 0.1 5.3e-06 25.5 0.0 2.2 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 ETS86376.1 - 2.7e-06 27.5 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS86376.1 - 0.0023 17.5 0.3 0.02 14.5 0.2 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 ETS86378.1 - 1.3e-27 96.7 5.1 1.9e-27 96.1 3.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86378.1 - 1.2e-26 93.9 0.9 1.4e-26 93.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86378.1 - 1e-12 48.0 2.1 1.6e-12 47.4 1.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS86378.1 - 0.035 13.7 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 ETS86379.1 - 3.5e-54 183.8 0.7 4.9e-54 183.3 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86379.1 - 1e-08 34.9 6.2 2.5e-08 33.6 4.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 ETS86380.1 - 7.2e-108 360.9 44.6 8.1e-108 360.7 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS86380.1 - 1.3e-26 93.1 48.9 1.6e-26 92.8 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 ETS86380.1 - 0.015 13.7 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) adh_short PF00106.20 ETS86381.1 - 2.3e-27 95.9 4.4 3.4e-27 95.3 3.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86381.1 - 2.8e-24 86.2 0.4 3.3e-24 85.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86381.1 - 2.5e-13 50.0 5.7 2.1e-12 47.0 4.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86381.1 - 3.7e-05 23.2 0.3 6.1e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 ETS86381.1 - 0.00059 18.8 0.1 0.00092 18.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 ETS86381.1 - 0.0039 17.0 0.3 0.022 14.6 0.3 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS86381.1 - 0.019 13.6 0.1 0.025 13.2 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 ETS86381.1 - 0.057 13.2 0.2 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 ETS86381.1 - 0.17 11.8 2.2 0.28 11.1 1.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 ETS86382.1 - 2.2e-22 80.1 0.0 3.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS86382.1 - 4.7e-14 51.4 0.0 2e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS86382.1 - 3.8e-11 42.8 0.0 4.4e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS86382.1 - 5.1e-08 32.2 0.0 4.3e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS86382.1 - 1.4e-06 28.1 0.1 0.0018 18.0 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 ETS86382.1 - 0.0002 20.5 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 ETS86382.1 - 0.00033 20.7 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 ETS86382.1 - 0.0006 18.9 0.1 0.0056 15.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 ETS86382.1 - 0.00064 18.7 0.8 0.0039 16.1 0.0 2.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS86382.1 - 0.0016 18.3 0.1 8.2 6.2 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 ETS86382.1 - 0.0039 17.4 0.0 0.031 14.5 0.0 2.4 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 ETS86382.1 - 0.02 13.8 0.0 0.082 11.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Ank_2 PF12796.2 ETS86383.1 - 2.3e-37 127.1 1.6 2.1e-13 50.3 0.0 6.3 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86383.1 - 2.3e-27 93.4 3.5 8.3e-06 25.3 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 ETS86383.1 - 4.6e-21 74.3 1.1 2.6e-07 30.6 0.0 6.7 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86383.1 - 2.9e-20 70.3 0.1 0.0012 18.8 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 ETS86383.1 - 4.4e-18 65.2 0.6 1.6e-08 34.8 0.0 5.9 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Avirulence PF03377.8 ETS86383.1 - 2.2e-05 23.3 0.3 4e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Xanthomonas avirulence protein, Avr/PthA GUCT PF08152.7 ETS86383.1 - 0.11 12.4 0.4 1.8 8.6 0.0 3.1 2 1 0 2 2 2 0 GUCT (NUC152) domain DUF3916 PF13079.1 ETS86385.1 - 0.043 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Vps35 PF03635.12 ETS86386.1 - 0 1024.4 0.0 0 1024.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF2360 PF10152.4 ETS86386.1 - 0.058 13.6 1.5 0.15 12.3 1.0 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MIP-T3 PF10243.4 ETS86387.1 - 0.00011 20.8 51.2 0.00014 20.5 35.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 ETS86387.1 - 0.0012 16.9 28.5 0.0014 16.7 19.8 1.1 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.10 ETS86387.1 - 0.0015 17.3 14.6 0.0016 17.1 10.1 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 ETS86387.1 - 0.0019 16.5 28.6 0.0021 16.4 19.8 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Mitofilin PF09731.4 ETS86387.1 - 0.0096 14.6 27.9 0.012 14.3 19.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein PLRV_ORF5 PF01690.12 ETS86387.1 - 0.17 11.0 23.4 0.21 10.6 16.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4551 PF15087.1 ETS86387.1 - 0.2 10.0 15.2 0.25 9.6 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nop14 PF04147.7 ETS86387.1 - 0.2 9.5 43.2 0.35 8.7 30.0 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 ETS86387.1 - 0.22 10.7 45.6 0.29 10.3 31.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF966 PF06136.8 ETS86387.1 - 0.69 9.2 20.9 0.93 8.8 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Asp-B-Hydro_N PF05279.6 ETS86387.1 - 0.75 9.5 41.8 1.2 8.9 29.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 ETS86387.1 - 1.4 8.2 49.5 3.1 7.1 34.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 ETS86387.1 - 2 7.8 43.1 3.9 6.8 29.9 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Utp14 PF04615.8 ETS86387.1 - 2.6 6.1 52.9 3.7 5.5 36.7 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2151 PF10221.4 ETS86387.1 - 4 5.5 20.2 4.6 5.2 14.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Parvo_coat PF00740.13 ETS86387.1 - 8.5 5.2 12.6 11 4.8 8.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SOBP PF15279.1 ETS86387.1 - 8.6 6.6 14.5 12 6.1 10.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Pilt PF15453.1 ETS86387.1 - 9 5.8 27.7 15 5.1 19.2 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions TFR_dimer PF04253.10 ETS86388.1 - 4.8e-20 71.3 0.0 7.6e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS86388.1 - 8e-20 71.3 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS86388.1 - 1.2e-06 28.0 0.0 4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 ETS86388.1 - 0.00054 19.5 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 E1-E2_ATPase PF00122.15 ETS86390.1 - 3.7e-19 68.6 1.0 5e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 ETS86390.1 - 3.1e-16 60.4 0.0 3.4e-15 57.0 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 ETS86390.1 - 5.1e-12 46.3 0.1 3.7e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS86390.1 - 1.1e-10 41.2 0.0 4.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS86390.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VPS9 PF02204.13 ETS86391.1 - 1.5e-30 105.2 0.1 2.7e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 ETS86391.1 - 1.7e-08 33.7 0.0 5.4e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 CUE domain DUF4158 PF13700.1 ETS86391.1 - 0.042 13.3 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) TauD PF02668.11 ETS86393.1 - 6.9e-51 173.4 0.0 8e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 ETS86394.1 - 1.3e-25 89.9 33.6 3e-25 88.6 23.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 ETS86395.1 - 7.3e-22 78.0 10.4 1.1e-19 71.0 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 ETS86396.1 - 5.2e-35 120.7 57.5 5.2e-35 120.7 39.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86396.1 - 3.8e-11 42.2 14.5 3.8e-11 42.2 10.0 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter PAS_9 PF13426.1 ETS86397.1 - 2.7e-19 69.4 0.0 1.6e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain RGS PF00615.14 ETS86397.1 - 3.3e-15 56.2 0.3 1e-14 54.6 0.2 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.19 ETS86397.1 - 4.3e-05 23.2 0.0 0.00029 20.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 ETS86397.1 - 0.00013 21.9 0.0 0.027 14.5 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 ETS86397.1 - 0.0055 16.7 0.0 0.034 14.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold Abhydrolase_4 PF08386.5 ETS86398.1 - 7.4e-21 73.9 0.1 1.1e-19 70.1 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 ETS86398.1 - 1.8e-13 50.6 0.0 8.3e-07 28.7 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS86398.1 - 5e-10 39.6 0.4 7.3e-09 35.8 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS86398.1 - 4.5e-05 23.2 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family NAD_binding_8 PF13450.1 ETS86399.1 - 4.4e-12 45.8 0.2 1.2e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS86399.1 - 7.7e-10 38.2 0.0 1.1e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS86399.1 - 3.6e-05 24.0 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS86399.1 - 0.00015 20.8 0.0 0.00024 20.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS86399.1 - 0.00017 21.7 0.0 0.00051 20.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS86399.1 - 0.00067 19.4 0.0 0.0034 17.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS86399.1 - 0.00075 19.4 0.0 0.0078 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS86399.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 ETS86399.1 - 0.0031 16.0 0.0 0.014 13.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 ETS86399.1 - 0.0049 15.9 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 ETS86399.1 - 0.013 14.6 0.7 0.059 12.4 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 ETS86399.1 - 0.041 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 ETS86399.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Ldh_1_N PF00056.18 ETS86399.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 ETS86401.1 - 1.6e-54 184.6 0.0 1.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dus PF01207.12 ETS86402.1 - 4.1e-33 114.5 0.0 5.3e-29 101.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Cyclin_N PF00134.18 ETS86403.1 - 2.8e-12 46.3 0.2 5.6e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 ETS86404.1 - 3.5e-52 172.5 13.5 5e-10 38.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 ETS86404.1 - 4.6e-16 57.7 1.1 1e-15 56.6 0.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 ETS86404.1 - 0.082 12.5 0.0 0.95 9.1 0.0 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Melibiase PF02065.13 ETS86405.1 - 2.4e-11 42.9 0.2 2.5e-06 26.4 0.0 2.6 2 1 1 3 3 3 2 Melibiase PBP PF01161.15 ETS86407.1 - 9.9e-10 38.4 0.9 1.2e-09 38.2 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SNF2_N PF00176.18 ETS86408.1 - 5e-32 110.8 0.0 2.5e-27 95.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 ETS86408.1 - 0.0028 17.1 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS86408.1 - 0.0036 17.1 0.1 0.013 15.3 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aldedh PF00171.17 ETS86409.1 - 1.3e-106 356.6 0.1 1.8e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.5 ETS86410.1 - 2.7e-09 36.1 0.1 1.5e-07 30.3 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 ETS86411.1 - 1.7e-21 76.7 14.7 1.7e-21 76.7 10.2 1.5 2 0 0 2 2 2 1 Rhomboid family Peptidase_M20 PF01546.23 ETS86412.1 - 3.3e-23 82.1 0.0 4.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS86412.1 - 8e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Ank_2 PF12796.2 ETS86413.1 - 1.3e-101 333.1 23.1 5.3e-18 65.1 0.1 8.9 1 1 9 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86413.1 - 1.1e-80 261.6 29.3 4.3e-09 35.7 0.0 14.5 14 1 0 14 14 13 13 Ankyrin repeat Ank_4 PF13637.1 ETS86413.1 - 9.3e-72 236.2 14.8 6.1e-10 39.3 0.0 12.9 4 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86413.1 - 1.1e-63 204.7 15.6 2.4e-05 24.1 0.0 14.8 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 ETS86413.1 - 7.9e-49 162.5 17.7 2.3e-09 37.2 0.0 10.0 7 4 2 9 9 8 8 Ankyrin repeats (many copies) NACHT PF05729.7 ETS86413.1 - 5.3e-07 29.4 0.1 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS86413.1 - 5.1e-05 23.4 0.0 0.00079 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS86413.1 - 0.00069 19.9 0.0 0.019 15.2 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 ETS86413.1 - 0.00094 19.2 0.1 0.0032 17.4 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Mur_ligase PF01225.20 ETS86413.1 - 0.0014 18.6 0.0 4 7.5 0.0 4.5 3 1 1 4 4 4 1 Mur ligase family, catalytic domain Nitro_FeMo-Co PF02579.12 ETS86413.1 - 0.0043 17.1 2.8 9.1 6.4 0.0 5.7 4 2 3 7 7 6 0 Dinitrogenase iron-molybdenum cofactor RNA_helicase PF00910.17 ETS86413.1 - 0.006 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 ETS86413.1 - 0.0097 16.2 0.0 0.034 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 ETS86413.1 - 0.04 12.8 0.6 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF258 PF03193.11 ETS86413.1 - 0.095 11.8 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETS86413.1 - 0.13 11.8 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Shigella_OspC PF06128.6 ETS86413.1 - 0.15 11.5 0.1 14 5.1 0.0 3.4 2 1 1 3 3 3 0 Shigella flexneri OspC protein gag-asp_proteas PF13975.1 ETS86413.1 - 0.24 11.2 8.0 66 3.4 0.2 5.9 5 1 0 5 5 5 0 gag-polyprotein putative aspartyl protease NACHT PF05729.7 ETS86415.1 - 3.2e-15 56.1 0.0 6.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS86415.1 - 4.9e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 ETS86415.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 ETS86415.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 ETS86415.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Vps23_core PF09454.5 ETS86417.1 - 0.043 13.4 0.3 9.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Vps23 core domain F-box PF00646.28 ETS86418.1 - 0.0086 15.7 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain FAD_binding_2 PF00890.19 ETS86422.1 - 1.3e-125 419.5 3.0 1.6e-125 419.2 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 ETS86422.1 - 7.5e-47 158.3 0.3 1.1e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 ETS86422.1 - 9.6e-07 28.8 0.0 0.0023 17.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS86422.1 - 1e-05 24.7 0.3 0.0073 15.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 ETS86422.1 - 3.2e-05 22.9 1.3 0.014 14.3 1.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 ETS86422.1 - 0.0011 17.9 0.1 0.0039 16.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS86422.1 - 0.0054 15.8 1.1 0.0075 15.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 ETS86422.1 - 0.06 11.8 0.8 0.2 10.0 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF600 PF04634.7 ETS86422.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DUF3818 PF12825.2 ETS86423.1 - 1.6e-134 447.9 6.0 2.3e-134 447.3 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 ETS86423.1 - 7.1e-43 145.5 0.6 1.8e-42 144.2 0.4 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 ETS86423.1 - 3e-16 59.2 1.1 7.1e-15 54.7 0.0 3.5 3 1 0 3 3 3 1 PX domain Myc_N PF01056.13 ETS86423.1 - 0.029 13.5 0.6 0.057 12.5 0.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Acetyltransf_11 PF13720.1 ETS86423.1 - 2.8 8.2 5.9 10 6.4 1.0 3.7 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Fib_alpha PF08702.5 ETS86424.1 - 0.00026 21.1 1.1 0.00052 20.1 0.7 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HrpB7 PF09486.5 ETS86424.1 - 0.0026 17.6 4.7 0.065 13.1 2.9 2.6 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) DUF2077 PF09850.4 ETS86424.1 - 0.018 14.4 0.5 0.046 13.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Spc7 PF08317.6 ETS86424.1 - 0.019 13.6 2.3 0.027 13.1 1.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 ETS86424.1 - 0.02 14.6 1.4 0.053 13.2 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 ETS86424.1 - 0.059 12.8 1.9 0.15 11.5 1.3 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF485 PF04341.7 ETS86424.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Occludin_ELL PF07303.8 ETS86424.1 - 0.091 13.5 0.8 0.22 12.2 0.2 1.9 2 0 0 2 2 2 0 Occludin homology domain DUF607 PF04678.8 ETS86424.1 - 0.44 10.4 2.5 1.3 8.9 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF4164 PF13747.1 ETS86424.1 - 0.52 10.4 5.1 0.47 10.6 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GP41 PF00517.12 ETS86424.1 - 0.69 9.4 3.0 0.45 10.0 0.6 1.7 1 1 0 1 1 1 0 Retroviral envelope protein Cgr1 PF03879.9 ETS86425.1 - 3.3e-38 130.2 31.2 3.8e-38 130.0 21.6 1.0 1 0 0 1 1 1 1 Cgr1 family AstE_AspA PF04952.9 ETS86425.1 - 0.065 12.0 0.2 0.067 12.0 0.2 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family OmpH PF03938.9 ETS86425.1 - 0.22 11.4 12.1 0.22 11.4 8.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PRP1_N PF06424.7 ETS86425.1 - 0.56 10.5 12.6 0.68 10.2 8.8 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GAGA_bind PF06217.7 ETS86425.1 - 1.6 8.6 13.6 1.8 8.4 9.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family EVC2_like PF12297.3 ETS86425.1 - 2.5 6.6 14.5 2.7 6.5 10.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF2422 PF10337.4 ETS86425.1 - 6 5.5 5.7 7.1 5.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RR_TM4-6 PF06459.7 ETS86425.1 - 6.3 6.6 15.1 7.3 6.3 10.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 ETS86425.1 - 10 5.8 8.5 10 5.8 5.9 1.1 1 0 0 1 1 1 0 DDHD domain F-box-like PF12937.2 ETS86427.1 - 7e-06 25.6 0.4 2.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 ETS86427.1 - 0.0014 18.2 0.0 0.0065 16.1 0.0 2.2 1 1 0 1 1 1 1 F-box domain VIT1 PF01988.14 ETS86428.1 - 0.0019 17.7 2.6 0.0024 17.3 1.8 1.1 1 0 0 1 1 1 1 VIT family Neur_chan_memb PF02932.11 ETS86428.1 - 0.028 14.3 2.0 6 6.6 2.0 2.1 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region P34-Arc PF04045.9 ETS86428.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc KLRAQ PF10205.4 ETS86429.1 - 0.13 12.3 0.9 0.15 12.1 0.6 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein SlyX PF04102.7 ETS86430.1 - 0.023 15.0 0.9 0.67 10.3 0.3 2.7 2 0 0 2 2 2 0 SlyX DUF3610 PF12272.3 ETS86430.1 - 0.025 14.2 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF4611 PF15387.1 ETS86431.1 - 0.41 10.8 14.3 0.18 11.9 1.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Dicty_REP PF05086.7 ETS86431.1 - 3.2 5.4 11.0 4.6 4.8 7.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TRP PF06011.7 ETS86432.1 - 4.5e-83 279.2 27.4 1.5e-82 277.5 19.0 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 ETS86432.1 - 2.6e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Amidohydro_2 PF04909.9 ETS86433.1 - 3.6e-47 161.2 0.2 4.3e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase AIRC PF00731.15 ETS86434.1 - 6.5e-61 204.0 0.7 6.5e-61 204.0 0.5 2.4 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.17 ETS86434.1 - 1e-50 171.4 0.0 2e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 ETS86434.1 - 3.2e-12 46.5 0.0 6.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS86434.1 - 5.8e-06 25.8 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 ETS86434.1 - 0.0012 19.1 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 2 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 ETS86434.1 - 0.032 13.3 0.0 0.065 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATPgrasp_Ter PF15632.1 ETS86434.1 - 0.083 11.6 0.0 0.61 8.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon HATPase_c PF02518.21 ETS86436.1 - 1.8e-11 43.6 0.0 4.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 ETS86436.1 - 4.3e-11 42.6 0.0 9.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 ETS86436.1 - 3.3e-07 29.7 0.0 1.1e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DMRL_synthase PF00885.14 ETS86437.1 - 6.7e-44 149.0 0.1 1e-25 90.1 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase E_Pc_C PF06752.7 ETS86437.1 - 0.023 14.2 0.3 0.03 13.8 0.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Tom37_C PF11801.3 ETS86438.1 - 1.6 8.5 6.2 3.8 7.3 3.6 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain Cation_efflux PF01545.16 ETS86439.1 - 2.7e-36 125.1 8.6 3.4e-36 124.7 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family zf-CCCH PF00642.19 ETS86441.1 - 1.1e-08 34.5 17.9 2.8e-07 30.0 1.5 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 ETS86441.1 - 1.7e-06 27.7 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS86441.1 - 0.00075 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS86441.1 - 0.0047 16.8 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Oxysterol_BP PF01237.13 ETS86442.1 - 1.5e-88 296.6 0.0 2.3e-88 296.0 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein SET PF00856.23 ETS86443.1 - 2.5e-13 50.6 0.0 5.3e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 ETS86443.1 - 1.8e-08 34.0 12.3 1.8e-08 34.0 8.5 2.4 2 0 0 2 2 2 1 MYND finger peroxidase PF00141.18 ETS86444.1 - 2.1e-20 73.2 0.1 3.5e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Peroxidase adh_short PF00106.20 ETS86445.1 - 1.6e-22 80.1 0.1 2.7e-22 79.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86445.1 - 6.9e-13 48.9 0.0 8.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86445.1 - 1.1e-07 31.7 0.1 3.2e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS86445.1 - 8.5e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS86445.1 - 0.00012 22.0 0.1 0.00015 21.8 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 ETS86445.1 - 0.051 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase B12-binding PF02310.14 ETS86445.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 B12 binding domain Eno-Rase_NADH_b PF12242.3 ETS86445.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Y_Y_Y PF07495.8 ETS86447.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain EphA2_TM PF14575.1 ETS86448.1 - 0.056 13.8 0.4 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_53 PF07745.8 ETS86449.1 - 1.1e-111 372.7 0.8 1.3e-111 372.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Ank_2 PF12796.2 ETS86452.1 - 3.5e-37 126.6 1.9 2.7e-11 43.6 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86452.1 - 3.4e-21 73.9 1.6 9.9e-08 31.4 0.0 5.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 ETS86452.1 - 2.3e-12 45.8 0.4 0.00013 21.8 0.0 5.3 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 ETS86452.1 - 3e-12 46.6 0.2 8.4e-06 26.1 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86452.1 - 2.4e-11 43.5 0.1 0.00034 20.7 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) HET PF06985.6 ETS86453.1 - 3.5e-23 82.2 0.1 7.4e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86455.1 - 2.3e-20 73.1 0.0 5.1e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86456.1 - 8.4e-22 77.8 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CMD PF02627.15 ETS86456.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Methyltransf_12 PF08242.7 ETS86457.1 - 0.00086 19.7 0.1 0.0026 18.1 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86457.1 - 0.0025 17.5 0.0 0.0058 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86457.1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LcnG-beta PF11632.3 ETS86457.1 - 0.069 12.9 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Lactococcin G-beta Peptidase_C12 PF01088.16 ETS86458.1 - 1.1e-18 67.1 0.0 1.4e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C12 PF01088.16 ETS86459.1 - 2.9e-32 111.6 0.0 3.3e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ank_2 PF12796.2 ETS86461.1 - 2.2e-60 200.9 4.9 3.8e-14 52.7 0.0 7.6 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS86461.1 - 1.1e-33 111.9 11.5 0.25 11.6 0.0 15.2 14 2 2 16 16 16 10 Ankyrin repeat Ank PF00023.25 ETS86461.1 - 5.1e-33 111.2 23.7 0.014 15.1 0.0 15.0 15 1 0 15 15 15 9 Ankyrin repeat Ank_4 PF13637.1 ETS86461.1 - 6.3e-25 87.0 11.6 0.00012 22.4 0.0 10.3 9 2 2 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86461.1 - 6e-15 54.9 7.4 0.049 13.8 0.0 9.3 8 2 5 13 13 13 4 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.1 ETS86463.1 - 2.9e-25 89.4 11.6 1.4e-17 64.4 2.0 3.1 3 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS86463.1 - 4.4e-12 46.3 6.3 1.8e-11 44.3 0.8 2.8 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 ETS86463.1 - 5.5e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ketoacyl-synt PF00109.21 ETS86466.1 - 3e-74 249.7 0.0 7.9e-74 248.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 ETS86466.1 - 9.7e-56 189.4 0.0 1.8e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 ETS86466.1 - 1.1e-47 162.6 0.0 2e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 ETS86466.1 - 4.5e-44 150.2 0.0 1.1e-43 148.9 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS86466.1 - 1.6e-34 119.1 0.0 3.9e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS86466.1 - 1.8e-32 111.6 0.5 6.4e-32 109.9 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS86466.1 - 1.1e-18 67.4 0.0 3.2e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86466.1 - 8.3e-14 51.6 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86466.1 - 6.3e-12 45.8 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86466.1 - 3.2e-10 40.5 0.0 9.6e-09 35.8 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86466.1 - 3.2e-09 36.5 0.0 8.3e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 ETS86466.1 - 2.5e-07 30.8 0.1 6.9e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 ETS86466.1 - 4e-06 26.0 0.0 1.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 ETS86466.1 - 4.2e-06 26.0 0.0 7.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS86466.1 - 0.00033 20.9 0.0 0.00086 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 ETS86466.1 - 0.00043 19.7 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.6 ETS86466.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) FAD_binding_3 PF01494.14 ETS86467.1 - 4.4e-27 95.0 0.0 7.8e-27 94.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS86467.1 - 2.7e-07 29.8 1.4 0.00042 19.3 0.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS86467.1 - 5.5e-07 28.8 0.4 2.3e-06 26.7 0.3 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS86467.1 - 2.9e-06 26.6 1.1 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 ETS86467.1 - 2.3e-05 23.4 0.1 4.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 ETS86467.1 - 3.1e-05 23.9 0.5 0.00015 21.7 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS86467.1 - 0.00097 19.0 0.1 0.0028 17.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS86467.1 - 0.0017 16.9 0.4 0.25 9.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 ETS86467.1 - 0.0019 18.2 0.1 0.0055 16.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS86467.1 - 0.0023 16.8 1.2 0.0037 16.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS86467.1 - 0.0026 18.1 0.8 0.02 15.2 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS86467.1 - 0.062 12.3 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 ETS86467.1 - 0.096 11.2 1.2 0.17 10.5 0.3 1.7 1 1 1 2 2 2 0 Tryptophan halogenase Rossmann-like PF10727.4 ETS86467.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_9 PF13454.1 ETS86467.1 - 0.77 9.5 2.4 12 5.6 0.4 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.21 ETS86468.1 - 9e-15 54.3 0.0 1.9e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS86468.1 - 6.8e-05 22.5 0.2 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS86468.1 - 9.8e-05 23.2 0.0 0.00023 22.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 ETS86469.1 - 1.6e-22 79.7 0.0 1.2e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1062 PF06353.7 ETS86469.1 - 0.12 12.6 0.1 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) FSH1 PF03959.8 ETS86470.1 - 2.4e-31 108.8 0.0 3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 ETS86470.1 - 5.7e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 ETS86470.1 - 0.0058 16.0 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 ETS86470.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF900 PF05990.7 ETS86470.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Aldose_epim PF01263.15 ETS86471.1 - 1.1e-26 93.7 0.0 1.3e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.11 ETS86472.1 - 2.6e-28 98.7 57.2 8.4e-27 93.7 35.5 4.7 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS86472.1 - 1.2e-08 33.6 12.9 2e-08 32.9 9.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 ETS86473.1 - 0.0024 16.7 0.2 0.0083 15.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 ETS86476.1 - 2.8e-20 72.8 0.3 3.6e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86476.1 - 1.1e-16 61.3 0.0 1.4e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 ETS86476.1 - 1.1e-06 28.0 0.2 2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS86476.1 - 0.00028 20.9 0.2 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS86476.1 - 0.0004 19.6 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 ETS86476.1 - 0.0093 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tyrosinase PF00264.15 ETS86478.1 - 4.1e-38 131.7 0.5 5.2e-38 131.4 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.14 ETS86478.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box FAD_binding_3 PF01494.14 ETS86479.1 - 7.2e-16 58.1 0.5 7.3e-06 25.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 ETS86479.1 - 1.7e-06 27.9 0.1 9.3e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS86479.1 - 1.7e-06 27.1 0.2 0.003 16.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS86479.1 - 3.2e-05 22.9 0.1 5.7e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS86479.1 - 9.7e-05 21.0 0.1 0.0044 15.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 ETS86479.1 - 0.00013 22.1 0.0 0.00034 20.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS86479.1 - 0.00018 21.4 0.8 0.0019 18.0 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 ETS86479.1 - 0.00041 19.3 0.2 0.00077 18.4 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS86479.1 - 0.00041 20.6 1.7 0.06 13.7 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS86479.1 - 0.00072 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 ETS86479.1 - 0.0083 15.0 0.2 0.13 11.1 0.1 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 ETS86479.1 - 0.016 14.3 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 ETS86479.1 - 0.025 13.6 0.1 0.91 8.5 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 ETS86479.1 - 0.12 12.1 0.7 11 5.7 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding p450 PF00067.17 ETS86480.1 - 2.2e-82 277.0 0.0 2.6e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3328 PF11807.3 ETS86481.1 - 1.6e-25 90.1 1.3 2e-25 89.7 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GSDH PF07995.6 ETS86483.1 - 4.9e-08 32.4 0.1 9.9e-08 31.4 0.0 1.5 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Pkinase PF00069.20 ETS86484.1 - 1.7e-09 37.1 0.0 5.3e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86484.1 - 2.1e-05 23.7 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PUA PF01472.15 ETS86485.1 - 1.1e-10 41.0 0.0 6.6e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 PUA domain Inhibitor_I78 PF11720.3 ETS86486.1 - 7e-13 48.1 0.0 9.3e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 ETS86486.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 Potato inhibitor I family DUF506 PF04720.7 ETS86487.1 - 0.44 10.1 3.9 0.71 9.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Peptidase_S64 PF08192.6 ETS86487.1 - 6.3 4.9 10.0 8.7 4.5 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 MIP-T3 PF10243.4 ETS86488.1 - 0.28 9.5 88.5 0.41 9.0 61.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NST1 PF13945.1 ETS86489.1 - 3.4e-53 180.5 8.3 3.4e-53 180.5 5.8 2.8 1 1 0 2 2 2 1 Salt tolerance down-regulator Rrn6 PF10214.4 ETS86489.1 - 0.26 9.3 9.3 0.4 8.7 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TMA7 PF09072.5 ETS86489.1 - 3.6 8.1 10.5 0.97 9.9 0.2 3.9 3 0 0 3 3 3 0 Translation machinery associated TMA7 Ras PF00071.17 ETS86490.1 - 4.5e-50 169.1 0.0 5.3e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS86490.1 - 1.7e-15 57.5 0.0 2.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 ETS86490.1 - 6.8e-07 28.6 0.0 9.8e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 ETS86490.1 - 0.0078 15.7 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 ETS86490.1 - 0.0081 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 ETS86490.1 - 0.026 13.7 0.0 0.053 12.7 0.0 1.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 ETS86490.1 - 0.057 13.3 0.0 0.088 12.7 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 ETS86490.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1397 PF07165.6 ETS86490.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) MRP-L28 PF09812.4 ETS86491.1 - 1.5e-07 31.3 1.0 2.2e-07 30.8 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 HET PF06985.6 ETS86492.1 - 0.00075 19.6 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Caps_synth PF05704.7 ETS86493.1 - 6.1e-08 32.1 0.1 2.4e-07 30.2 0.1 1.9 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 ETS86493.1 - 3.6e-05 24.0 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cys_rich_VLP PF14194.1 ETS86493.1 - 6.8 6.5 5.6 5.1 6.9 0.2 2.6 3 0 0 3 3 3 0 Cysteine-rich VLP FTA2 PF13095.1 ETS86495.1 - 8.5e-24 84.3 0.0 6.7e-23 81.3 0.0 2.2 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 ETS86495.1 - 0.016 14.3 0.1 2.3 7.3 0.0 2.7 2 1 1 3 3 3 0 Protein kinase domain FYVE PF01363.16 ETS86496.1 - 7.5e-22 77.0 1.5 7.5e-22 77.0 1.0 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 ETS86496.1 - 7.1e-09 35.3 25.0 2.2e-08 33.7 2.8 3.7 3 0 0 3 3 3 1 Ring finger domain Rad50_zn_hook PF04423.9 ETS86496.1 - 0.00024 20.4 0.9 0.27 10.7 0.1 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4 PF00097.20 ETS86496.1 - 0.0008 19.0 1.4 0.0008 19.0 1.0 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 ETS86496.1 - 0.0012 18.7 4.0 0.0012 18.7 2.8 3.8 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS86496.1 - 0.0029 17.6 2.2 0.0029 17.6 1.5 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger zf-HC5HC2H PF13771.1 ETS86496.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.1 3 0 0 3 3 3 0 PHD-like zinc-binding domain FYVE_2 PF02318.11 ETS86496.1 - 0.34 10.8 7.6 0.029 14.2 1.3 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 ETS86496.1 - 2.1 8.1 25.4 1.8 8.3 2.4 3.6 3 0 0 3 3 3 0 zinc-RING finger domain zinc-ribbons_6 PF07191.7 ETS86496.1 - 3.1 7.6 10.2 9.3 6.1 3.5 2.7 2 0 0 2 2 2 0 zinc-ribbons Elf1 PF05129.8 ETS86496.1 - 4.3 7.1 7.9 6.7 6.4 1.7 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Exo_endo_phos PF03372.18 ETS86497.1 - 2.1e-08 34.4 0.1 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rick_17kDa_Anti PF05433.10 ETS86498.1 - 6.3 6.5 10.9 0.79 9.4 0.7 2.7 3 0 0 3 3 3 0 Glycine zipper 2TM domain GalKase_gal_bdg PF10509.4 ETS86499.1 - 2.1e-19 68.5 0.0 3.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 ETS86499.1 - 4.4e-13 49.2 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 ETS86499.1 - 7.2e-13 48.4 1.4 2.4e-12 46.7 1.0 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_3 PF01381.17 ETS86499.1 - 0.045 13.6 1.2 8.2 6.3 0.3 3.5 3 1 1 4 4 4 0 Helix-turn-helix Sigma70_r4_2 PF08281.7 ETS86499.1 - 0.19 11.2 0.4 1.6 8.2 0.0 2.3 1 1 1 2 2 2 0 Sigma-70, region 4 AMP-binding PF00501.23 ETS86501.1 - 2e-80 270.2 0.0 2.9e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS86501.1 - 3.7e-05 24.5 0.0 0.00011 23.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_6 PF08030.7 ETS86501.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Cytochrom_B561 PF03188.11 ETS86501.1 - 0.26 11.1 4.3 0.97 9.2 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 ECH PF00378.15 ETS86502.1 - 2.2e-65 220.2 0.5 1.4e-64 217.5 0.3 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS86502.1 - 0.0045 16.7 0.2 0.088 12.5 0.0 2.6 3 0 0 3 3 3 1 Peptidase family S49 bZIP_1 PF00170.16 ETS86503.1 - 7.7e-11 41.7 15.5 1.3e-10 41.0 10.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS86503.1 - 1.2e-07 31.3 12.4 2.5e-07 30.4 8.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS86503.1 - 0.00077 19.7 10.1 0.00077 19.7 7.0 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor TBCA PF02970.11 ETS86503.1 - 0.0017 18.3 5.5 0.0025 17.8 3.8 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A GBP_C PF02841.9 ETS86503.1 - 0.064 12.4 9.9 0.086 12.0 6.8 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Exonuc_VII_L PF02601.10 ETS86503.1 - 0.081 12.1 4.8 0.096 11.8 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TRAP-gamma PF07074.7 ETS86503.1 - 0.11 12.0 0.5 0.15 11.5 0.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Ndc1_Nup PF09531.5 ETS86503.1 - 0.55 8.5 3.5 0.67 8.3 2.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bap31 PF05529.7 ETS86503.1 - 5.8 6.3 9.6 8.2 5.8 6.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PI3_PI4_kinase PF00454.22 ETS86504.1 - 3.1e-40 138.1 0.0 1.7e-39 135.7 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 ETS86504.1 - 7.5e-25 87.1 0.0 1.8e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.21 ETS86505.1 - 3.4e-30 104.7 0.2 2.7e-29 101.8 0.2 2.0 2 1 0 2 2 2 1 Proteasome subunit YTH PF04146.10 ETS86506.1 - 1.6e-56 189.7 0.0 2.3e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 ETS86506.1 - 0.0044 16.6 0.0 0.016 14.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS86506.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS86506.1 - 0.04 13.7 0.1 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 ETS86507.1 - 2e-18 66.0 0.1 2.9e-13 49.5 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4432 PF14486.1 ETS86507.1 - 0.049 12.1 0.0 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Autophagy_N PF03986.8 ETS86507.1 - 0.099 12.4 2.1 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain Med13_C PF06333.7 ETS86507.1 - 0.42 9.0 3.3 0.53 8.7 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal TraG-D_C PF12696.2 ETS86508.1 - 0.28 11.0 2.0 0.42 10.4 1.4 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG GDPD PF03009.12 ETS86509.1 - 2.5e-45 154.9 0.0 7.8e-45 153.3 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 ETS86509.1 - 7.1e-34 116.0 0.0 2e-12 47.2 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86509.1 - 1.7e-15 55.9 6.4 3.1e-05 23.5 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 ETS86509.1 - 4.4e-14 52.1 4.2 2.3e-07 30.8 0.0 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) 2OG-FeII_Oxy PF03171.15 ETS86509.1 - 6e-12 45.7 0.0 1.8e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ank_3 PF13606.1 ETS86509.1 - 4.3e-10 38.8 1.1 0.049 13.8 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 ETS86509.1 - 5.9e-09 36.2 0.1 9.6e-05 22.7 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DIOX_N PF14226.1 ETS86509.1 - 1.7e-05 25.3 0.0 3.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SPX PF03105.14 ETS86509.1 - 0.14 11.9 3.6 0.34 10.6 2.5 1.7 1 1 0 1 1 1 0 SPX domain G-alpha PF00503.15 ETS86511.1 - 5.9e-77 258.9 7.8 8.7e-77 258.4 1.7 2.0 1 1 0 2 2 2 1 G-protein alpha subunit Arf PF00025.16 ETS86511.1 - 9.7e-11 41.2 0.3 3e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 ETS86511.1 - 0.00013 21.3 0.1 0.00035 20.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 ETS86511.1 - 0.00021 21.7 0.0 0.074 13.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 ETS86511.1 - 0.0017 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 ETS86511.1 - 0.0019 18.1 0.1 0.078 12.9 0.0 2.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 ETS86511.1 - 0.0079 16.5 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter NOG1 PF06858.9 ETS86511.1 - 0.0093 15.8 0.1 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Arch_ATPase PF01637.13 ETS86511.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 ETS86511.1 - 0.05 13.2 0.0 4.8 6.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 ETS86511.1 - 0.073 13.0 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS86511.1 - 0.21 12.4 0.9 1.2 9.9 0.6 2.5 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 ETS86512.1 - 7.9e-08 31.9 0.8 1.4e-07 31.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS86512.1 - 1.1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 ETS86512.1 - 0.11 12.3 1.6 0.28 11.0 0.4 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPR_12 PF13424.1 ETS86513.1 - 2.3e-42 142.7 2.7 1.9e-17 62.9 0.1 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 ETS86513.1 - 7.9e-33 111.4 0.8 9.2e-10 38.1 0.0 5.4 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS86513.1 - 4.4e-08 32.6 0.0 4.8e-05 22.9 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 ETS86513.1 - 4.7e-07 29.1 0.1 0.35 10.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS86513.1 - 7.3e-07 28.5 0.7 0.48 10.1 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 ETS86513.1 - 2.5e-05 23.2 0.0 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_2 PF07719.12 ETS86513.1 - 2.7e-05 23.7 0.8 3 7.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 ETS86513.1 - 0.00027 20.6 0.0 0.00096 18.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain TPR_19 PF14559.1 ETS86513.1 - 0.0026 18.0 0.1 0.051 13.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 ETS86513.1 - 0.0046 17.4 0.5 14 6.6 0.1 4.1 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS86513.1 - 0.005 16.5 0.1 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS86513.1 - 0.013 15.6 0.1 5.7 7.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 ETS86513.1 - 0.031 14.9 0.0 0.22 12.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pectinesterase PF01095.14 ETS86514.1 - 1e-152 506.9 77.0 6.6e-45 152.9 3.8 6.7 7 0 0 7 7 7 5 Pectinesterase p450 PF00067.17 ETS86515.1 - 2.2e-08 33.0 0.0 5.4e-07 28.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.13 ETS86516.1 - 6.7e-33 113.8 0.0 9e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HEAT_2 PF13646.1 ETS86517.1 - 1.6e-13 50.6 3.2 9e-06 25.8 0.2 2.8 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 ETS86517.1 - 1.7e-09 36.9 1.8 0.041 13.9 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 ETS86517.1 - 9.4e-07 29.1 8.1 0.015 15.7 0.4 4.1 2 1 3 5 5 5 4 HEAT-like repeat HEAT_PBS PF03130.11 ETS86517.1 - 0.00014 21.9 1.7 0.053 13.9 0.2 3.6 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.18 ETS86517.1 - 0.00033 20.3 0.1 0.079 12.8 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 ETS86517.1 - 0.032 12.5 1.3 1.2 7.4 0.1 2.4 1 1 1 2 2 2 0 Adaptin N terminal region Cohesin_HEAT PF12765.2 ETS86517.1 - 0.35 10.8 6.4 1.7 8.6 0.0 3.7 4 1 1 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 ETS86518.1 - 1.6e-27 95.6 6.3 1.5e-08 34.7 0.0 5.0 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 ETS86518.1 - 3.5e-26 88.8 1.9 0.0037 17.2 0.0 7.2 6 0 0 6 6 6 6 HEAT repeat HEAT_EZ PF13513.1 ETS86518.1 - 6.3e-14 51.9 6.1 0.0046 17.3 0.0 6.1 4 2 2 6 6 6 5 HEAT-like repeat Cohesin_HEAT PF12765.2 ETS86518.1 - 2.8e-08 33.5 8.2 0.014 15.3 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 ETS86518.1 - 7.9e-07 29.0 0.2 0.07 12.9 0.0 4.0 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 ETS86518.1 - 7.5e-06 26.2 0.2 5.4 7.4 0.0 5.2 3 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region PFO_beta_C PF12367.3 ETS86518.1 - 0.0035 17.2 0.0 36 4.3 0.0 5.2 4 1 1 5 5 5 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal F-box-like PF12937.2 ETS86518.1 - 0.0044 16.7 0.8 1.1e+02 2.5 0.0 5.5 6 0 0 6 6 6 0 F-box-like Arm PF00514.18 ETS86518.1 - 0.017 14.9 0.0 6.1 6.8 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat EHN PF06441.7 ETS86518.1 - 0.023 14.6 2.5 3.4 7.6 0.2 3.9 3 1 1 4 4 4 0 Epoxide hydrolase N terminus PaaSYMP PF14738.1 ETS86518.1 - 0.048 13.3 5.7 3.5 7.3 0.1 3.6 2 1 0 3 3 3 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DNA_alkylation PF08713.6 ETS86518.1 - 0.19 11.2 2.7 5 6.5 0.0 2.6 2 1 0 2 2 2 0 DNA alkylation repair enzyme DUF2235 PF09994.4 ETS86519.1 - 2.9e-53 181.0 0.0 2.3e-52 178.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HET PF06985.6 ETS86520.1 - 3.1e-30 105.1 0.0 7.1e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 ETS86521.1 - 6.4e-52 176.1 0.0 7.3e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 ETS86522.1 - 1.7e-29 102.8 0.4 2.8e-29 102.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86522.1 - 7.8e-15 55.2 0.0 1.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86522.1 - 2e-12 47.1 0.1 3.1e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS86522.1 - 3.8e-08 33.5 0.2 7e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS86522.1 - 2.7e-07 30.2 0.1 5e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS86522.1 - 0.0005 19.0 0.0 0.00086 18.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS86522.1 - 0.0087 14.9 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 ETS86522.1 - 0.011 15.4 1.7 0.023 14.4 0.4 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 ETS86522.1 - 0.041 13.0 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 ETS86522.1 - 0.043 13.0 0.0 0.38 9.9 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family FAD_binding_4 PF01565.18 ETS86523.1 - 8.5e-21 73.8 0.5 1.4e-20 73.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS86523.1 - 0.036 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF3425 PF11905.3 ETS86524.1 - 1.3e-28 99.5 1.4 2.7e-28 98.5 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) zf-C2H2_jaz PF12171.3 ETS86525.1 - 5.8e-16 58.1 16.7 4.9e-07 29.7 2.2 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 ETS86525.1 - 4.2e-12 45.8 11.4 0.0013 18.9 0.3 5.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 ETS86525.1 - 5e-12 45.8 20.6 0.0051 16.8 2.4 5.8 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 ETS86525.1 - 5.1e-09 35.8 30.2 0.043 14.1 0.2 7.0 7 0 0 7 7 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS86525.1 - 2.8e-08 33.6 29.3 0.049 13.9 1.5 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 ETS86525.1 - 4e-07 29.9 36.9 0.0089 16.3 0.8 7.1 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 ETS86525.1 - 0.021 14.6 26.8 0.3 11.0 0.7 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-DBF PF07535.7 ETS86525.1 - 0.066 12.9 17.2 0.26 10.9 1.1 4.9 4 1 1 5 5 5 0 DBF zinc finger AKAP95 PF04988.7 ETS86525.1 - 3.4 7.4 10.1 5.7 6.6 0.3 3.2 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-FCS PF06467.9 ETS86525.1 - 3.5 7.3 10.0 21 4.8 0.0 3.9 4 1 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.11 ETS86525.1 - 10 6.3 17.5 17 5.6 0.1 4.8 5 0 0 5 5 4 0 C1 domain Sugar_tr PF00083.19 ETS86526.1 - 2.6e-81 273.5 31.9 3.2e-81 273.2 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86526.1 - 2.9e-21 75.5 41.3 7.6e-19 67.6 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 ETS86526.1 - 3.4 7.5 7.1 0.43 10.4 0.5 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) p450 PF00067.17 ETS86527.1 - 8.4e-52 176.2 0.0 1.2e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF924 PF06041.6 ETS86528.1 - 6.3e-46 156.4 0.1 7.6e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) MFS_1 PF07690.11 ETS86530.1 - 1.1e-23 83.5 43.9 1.1e-23 83.5 30.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS86530.1 - 0.029 14.3 1.2 0.029 14.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Peptidase_M20 PF01546.23 ETS86531.1 - 1.7e-25 89.6 0.1 2.4e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS86531.1 - 1.8e-05 24.4 0.0 6.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain TFR_dimer PF04253.10 ETS86532.1 - 3.4e-21 75.0 0.0 5.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 ETS86532.1 - 3e-15 56.4 0.0 5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 ETS86532.1 - 7e-08 32.0 0.1 1.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 ETS86532.1 - 0.012 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MFS_1 PF07690.11 ETS86533.1 - 1.3e-24 86.6 31.2 1.3e-24 86.6 21.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS86533.1 - 0.00084 19.0 1.6 0.00084 19.0 1.1 2.4 2 0 0 2 2 2 1 MFS_1 like family TauD PF02668.11 ETS86534.1 - 3.8e-23 82.4 0.2 5e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BtpA PF03437.10 ETS86534.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 BtpA family AAA_16 PF13191.1 ETS86535.1 - 2.4e-07 30.9 0.2 1.8e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 ETS86535.1 - 1.2e-06 28.2 1.6 5.1e-06 26.2 1.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS86535.1 - 1.1e-05 25.5 0.1 4.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS86535.1 - 0.0064 15.9 0.1 0.06 12.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 ETS86535.1 - 0.02 15.1 0.0 0.21 11.8 0.0 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS86535.1 - 0.027 13.8 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 ETS86535.1 - 0.058 12.9 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS86535.1 - 0.14 13.0 0.1 1.5 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS86535.1 - 0.21 11.9 0.6 1.4 9.1 0.4 2.5 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.23 ETS86536.1 - 1.8e-36 125.4 0.0 2.9e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS86536.1 - 5.1e-25 87.8 0.0 8.1e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 ETS86536.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS86536.1 - 0.0022 18.1 0.1 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 ETS86536.1 - 0.0081 16.0 0.2 0.083 12.8 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS86536.1 - 0.075 12.6 0.2 0.52 9.9 0.0 2.5 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 ETS86536.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.21 ETS86538.1 - 7e-71 238.6 0.1 1.7e-70 237.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 ETS86538.1 - 9.1e-34 115.8 0.0 1.8e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 ETS86538.1 - 4.7e-25 88.5 0.0 9.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 ETS86538.1 - 1.2e-19 70.3 10.0 7.7e-12 45.3 1.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 ETS86538.1 - 1.8e-15 56.9 0.0 2.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 ETS86538.1 - 6.9e-15 55.3 0.0 1.9e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 ETS86538.1 - 1e-11 44.8 0.0 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 ETS86538.1 - 4.4e-09 36.2 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 ETS86538.1 - 6.3e-09 35.7 0.5 5.9e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 ETS86538.1 - 2.5e-07 30.3 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 ETS86538.1 - 1.6e-06 28.2 0.9 7.4e-06 25.9 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 ETS86538.1 - 1.3e-05 25.5 0.0 3.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 ETS86538.1 - 0.00016 20.9 0.0 0.042 13.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thiolase_N PF00108.18 ETS86538.1 - 0.002 17.1 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 ETS86538.1 - 0.0031 16.9 0.0 0.0097 15.3 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 ETS86538.1 - 0.0087 16.6 0.0 0.062 13.8 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain PHB_depo_C PF06850.6 ETS86538.1 - 0.072 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus p450 PF00067.17 ETS86539.1 - 5.6e-56 189.9 0.0 7.3e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS86540.1 - 3.8e-73 246.5 0.0 4.6e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 ETS86541.1 - 2.5e-76 257.2 0.3 4.5e-67 226.7 0.0 2.7 3 0 0 3 3 3 2 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.18 ETS86542.1 - 3.3e-20 71.9 0.5 2.5e-19 69.1 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS86542.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 ETS86543.1 - 2.3e-17 63.3 0.1 4.4e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86543.1 - 1.7e-13 50.6 0.1 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS86545.1 - 7.6e-19 68.2 0.2 1e-18 67.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86545.1 - 4.4e-09 36.2 0.1 6.5e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86545.1 - 2.8e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 ETS86545.1 - 3.6e-06 26.9 0.0 4.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS86545.1 - 0.00031 20.8 0.1 0.00056 19.9 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS86545.1 - 0.011 15.5 0.1 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 ETS86545.1 - 0.032 13.4 0.1 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.10 ETS86545.1 - 0.12 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Nop14 PF04147.7 ETS86548.1 - 0.78 7.5 22.0 0.88 7.4 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family DEC-1_N PF04625.8 ETS86548.1 - 0.82 8.2 8.7 1.1 7.8 6.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Daxx PF03344.10 ETS86548.1 - 2.3 6.5 25.8 3.4 6.0 17.9 1.3 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 ETS86548.1 - 2.6 7.5 19.3 3.6 7.1 13.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BTV_NS2 PF04514.7 ETS86548.1 - 5.5 5.7 10.7 7.8 5.2 7.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 ETS86548.1 - 8.7 4.9 27.5 11 4.5 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fe_dep_repr_C PF02742.10 ETS86550.1 - 0.087 12.5 1.4 8.6 6.1 0.3 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain AA_permease PF00324.16 ETS86551.1 - 7.6e-105 350.9 43.8 9.5e-105 350.6 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS86551.1 - 4.9e-26 91.2 49.1 8.1e-26 90.5 33.8 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3445 PF11927.3 ETS86552.1 - 3.9e-47 160.7 0.0 5e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 ETS86553.1 - 2e-34 118.8 7.1 2.5e-34 118.5 4.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86553.1 - 7.8e-08 32.1 4.1 7.8e-08 32.1 2.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 ETS86554.1 - 1.9e-18 66.9 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C2 PF00168.25 ETS86555.1 - 1.4e-21 76.1 0.1 1.2e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain 2-Hacid_dh_C PF02826.14 ETS86556.1 - 2.8e-42 143.8 0.0 1.1e-41 141.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS86556.1 - 1.4e-21 76.3 0.0 1.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 ETS86556.1 - 0.024 13.9 0.3 0.26 10.6 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 ETS86556.1 - 0.079 13.2 0.0 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.12 ETS86556.1 - 0.33 11.3 2.9 18 5.8 0.5 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CUE PF02845.11 ETS86557.1 - 5e-10 38.6 0.0 8.1e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain Lentiviral_Tat PF02998.9 ETS86559.1 - 1.5 8.7 4.2 0.34 10.7 0.2 2.0 2 0 0 2 2 2 0 Lentiviral Tat protein Kelch_5 PF13854.1 ETS86561.1 - 1.3e-13 50.5 6.0 1.3e-07 31.3 0.1 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 ETS86561.1 - 1e-09 38.2 14.7 0.00059 19.9 0.0 6.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS86561.1 - 2.4e-08 33.6 11.5 0.019 14.7 0.2 6.3 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 ETS86561.1 - 9e-08 31.9 10.7 0.17 12.0 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 ETS86561.1 - 0.00085 18.9 6.6 0.13 12.0 0.0 4.8 6 0 0 6 6 6 2 Kelch motif SKG6 PF08693.5 ETS86561.1 - 0.0093 15.2 0.0 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 ETS86561.1 - 0.13 11.8 14.2 0.091 12.3 0.3 4.9 6 0 0 6 6 6 0 Kelch motif OPT PF03169.10 ETS86562.1 - 4.5e-149 497.7 34.4 5.5e-149 497.4 23.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HTH_Tnp_Tc5 PF03221.11 ETS86562.1 - 0.09 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain SET PF00856.23 ETS86564.1 - 1.3e-11 45.0 0.0 1.7e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 SET domain NCD2 PF04905.8 ETS86565.1 - 0.16 11.7 2.9 0.21 11.3 1.9 1.4 1 1 0 1 1 1 0 NAB conserved region 2 (NCD2) XkdW PF09636.5 ETS86566.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 XkdW protein HET PF06985.6 ETS86567.1 - 7.3e-29 100.7 0.9 1.1e-28 100.1 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86568.1 - 1.7e-24 86.5 0.0 3.2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 ETS86569.1 - 0.0056 16.5 2.9 0.17 11.8 0.5 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS86569.1 - 0.0068 16.0 0.1 0.91 9.2 0.0 2.8 2 0 0 2 2 2 2 TPR repeat DUF1515 PF07439.6 ETS86569.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CHAT PF12770.2 ETS86570.1 - 3.8e-09 36.0 0.4 6.6e-09 35.3 0.3 1.4 1 1 0 1 1 1 1 CHAT domain Pro-kuma_activ PF09286.6 ETS86571.1 - 0.03 14.3 0.1 0.37 10.8 0.0 2.7 1 1 0 1 1 1 0 Pro-kumamolisin, activation domain CMAS PF02353.15 ETS86571.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HET PF06985.6 ETS86575.1 - 1e-31 109.9 0.0 2.1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS86576.1 - 3.6e-05 23.9 0.0 0.28 11.5 0.0 3.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS86576.1 - 0.00019 21.8 0.0 0.72 10.4 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 ETS86576.1 - 0.0077 16.0 0.0 30 4.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat PNP_UDP_1 PF01048.15 ETS86576.1 - 0.034 13.1 0.0 0.075 12.0 0.0 1.7 1 1 0 1 1 1 0 Phosphorylase superfamily PNP_UDP_1 PF01048.15 ETS86577.1 - 2.6e-11 42.9 1.0 2e-10 40.0 0.7 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 ETS86578.1 - 3.3e-134 437.5 28.9 5e-19 68.4 0.0 7.0 2 1 9 11 11 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86578.1 - 1.2e-72 236.2 34.8 1.1e-06 28.1 0.0 13.5 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 ETS86578.1 - 1.3e-48 162.5 11.0 1.5e-06 28.5 0.1 10.6 1 1 9 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS86578.1 - 1.4e-46 155.4 20.8 4e-05 23.7 0.1 12.5 1 1 11 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86578.1 - 4.9e-45 147.0 13.4 0.00016 21.5 0.0 13.6 13 0 0 13 13 13 10 Ankyrin repeat NACHT PF05729.7 ETS86578.1 - 1.2e-07 31.5 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS86578.1 - 1.8e-07 31.3 0.1 9.8e-07 28.9 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 ETS86578.1 - 0.0002 21.5 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 ETS86578.1 - 0.049 13.9 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 ETS86578.1 - 0.051 12.4 0.0 0.098 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 ETS86578.1 - 0.073 12.0 0.6 3.1 6.6 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 ETS86578.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 ETS86578.1 - 0.21 10.9 0.2 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain MFS_1 PF07690.11 ETS86579.1 - 4.1e-18 65.2 58.2 2.7e-16 59.2 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86579.1 - 0.00076 18.1 11.5 0.00076 18.1 8.0 3.4 4 0 0 4 4 4 2 Sugar (and other) transporter Peptidase_M56 PF05569.6 ETS86579.1 - 0.04 12.8 0.8 0.17 10.7 0.1 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2569 PF10754.4 ETS86580.1 - 0.04 14.1 1.6 0.061 13.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1182 PF06681.8 ETS86581.1 - 0.13 11.4 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) HupE_UreJ_2 PF13795.1 ETS86581.1 - 0.13 11.7 0.2 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 HupE / UreJ protein DUF4291 PF14124.1 ETS86582.1 - 6.1e-64 214.9 0.1 7.3e-64 214.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) SKG6 PF08693.5 ETS86582.1 - 1.5 8.2 3.6 2.6 7.4 2.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HTH_11 PF08279.7 ETS86584.1 - 0.082 12.5 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 HTH domain Ribosomal_L10 PF00466.15 ETS86585.1 - 4.2e-25 87.5 0.1 8.8e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 ETS86585.1 - 2.3e-20 72.7 6.5 3.9e-20 72.0 2.7 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 ETS86586.1 - 1.8e-77 259.9 0.0 2.8e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS86586.1 - 1.1e-41 142.8 3.5 1.7e-41 142.2 2.4 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETS86586.1 - 8.5e-20 70.8 0.0 3.3e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 ETS86586.1 - 1.8e-08 34.5 0.0 9.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 ETS86586.1 - 6.4e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 ETS86586.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DnaJ PF00226.26 ETS86587.1 - 7.2e-25 86.5 3.8 1.7e-24 85.2 2.7 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 ETS86587.1 - 6.4e-22 77.2 0.1 4e-17 61.8 0.0 2.8 2 1 1 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 ETS86587.1 - 3.2e-13 49.5 19.1 6.1e-13 48.6 13.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 ETS86587.1 - 0.079 12.6 9.7 0.34 10.6 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 ETS86587.1 - 0.087 12.8 0.4 25 4.9 0.0 2.8 2 0 0 2 2 2 0 zinc-finger zinc-ribbons_6 PF07191.7 ETS86587.1 - 0.51 10.1 6.0 7.4 6.4 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 ETS86587.1 - 0.92 9.3 6.0 8.9 6.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Pkinase PF00069.20 ETS86588.1 - 3.8e-37 127.8 0.0 4.6e-22 78.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86588.1 - 1.2e-14 54.0 0.0 1.1e-13 50.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 ETS86588.1 - 6e-07 29.4 0.0 9.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS86588.1 - 0.0077 15.2 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.27 ETS86589.1 - 1.6e-06 27.7 0.2 0.013 15.3 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 ETS86589.1 - 2.7e-05 23.3 0.0 4.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region VCBS PF13517.1 ETS86589.1 - 0.01 16.2 0.1 6.5 7.1 0.0 3.2 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella bZIP_2 PF07716.10 ETS86590.1 - 0.0011 18.7 5.0 0.0016 18.1 3.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 ETS86590.1 - 0.0016 18.3 5.4 0.0029 17.5 3.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Glyco_hydro_38 PF01074.17 ETS86591.1 - 1.1e-90 303.6 1.2 1.1e-90 303.6 0.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 ETS86591.1 - 1.8e-73 247.9 0.2 6e-73 246.2 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 ETS86591.1 - 1.7e-24 85.8 0.0 3.6e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain CAP_GLY PF01302.20 ETS86592.1 - 8.5e-18 63.8 0.5 2e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 CAP-Gly domain BLOC1_2 PF10046.4 ETS86592.1 - 0.0059 16.7 11.9 0.044 13.9 1.0 3.6 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 ETS86592.1 - 0.026 14.7 7.5 0.2 11.9 0.8 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 ETS86592.1 - 0.096 11.3 25.7 0.17 10.5 3.0 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein Med4 PF10018.4 ETS86592.1 - 0.17 11.2 21.4 0.32 10.3 2.2 3.5 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 FUSC PF04632.7 ETS86592.1 - 0.23 9.8 18.2 0.17 10.2 9.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 ETS86592.1 - 0.24 10.5 7.1 8 5.5 3.6 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FliD_N PF02465.13 ETS86592.1 - 0.47 10.8 11.1 5.5 7.4 0.1 3.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TMF_DNA_bd PF12329.3 ETS86592.1 - 1.2 9.0 40.8 0.55 10.0 2.0 6.1 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 ETS86592.1 - 1.7 8.1 19.1 0.066 12.7 2.3 3.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 ETS86592.1 - 2 7.8 27.3 0.63 9.4 2.6 3.8 3 1 1 4 4 4 0 Phage minor structural protein GP20 zf-CCHC_4 PF14392.1 ETS86592.1 - 2.3 7.9 4.1 5.3 6.7 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF3584 PF12128.3 ETS86592.1 - 2.4 5.3 28.6 3.9 4.6 19.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 ETS86592.1 - 3.2 6.1 21.5 0.14 10.6 7.1 2.3 1 1 1 2 2 2 0 AAA domain Cauli_AT PF03233.8 ETS86592.1 - 4.8 6.8 8.6 3.1 7.4 1.0 2.8 2 1 1 3 3 3 0 Aphid transmission protein Fez1 PF06818.10 ETS86592.1 - 5.9 6.8 34.7 0.32 10.9 11.5 3.3 2 1 1 3 3 3 0 Fez1 Occludin_ELL PF07303.8 ETS86592.1 - 6.8 7.4 15.4 1.1 9.9 1.7 3.3 3 0 0 3 3 3 0 Occludin homology domain HEAT_2 PF13646.1 ETS86593.1 - 0.09 13.0 3.3 0.51 10.6 0.1 3.0 3 1 0 3 3 3 0 HEAT repeats Nop14 PF04147.7 ETS86594.1 - 1.2e-254 847.1 34.4 1.6e-254 846.8 23.9 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.1 ETS86595.1 - 1.6e-18 65.9 3.8 5.5e-18 64.2 2.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 ETS86595.1 - 9.5e-09 34.9 0.1 2.1e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 ETS86595.1 - 5.1 7.0 9.8 0.097 12.5 0.4 2.9 3 0 0 3 3 3 0 DExH-box splicing factor binding site PPR_2 PF13041.1 ETS86596.1 - 7.1e-09 35.4 0.0 0.31 11.0 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.1 ETS86596.1 - 6.1e-05 22.9 2.4 2.9 8.3 0.0 6.0 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 ETS86596.1 - 0.0013 18.6 5.0 12 6.1 0.1 6.1 6 0 0 6 6 6 1 PPR repeat ORC3_N PF07034.6 ETS86597.1 - 8.3e-41 140.0 2.2 8.3e-41 140.0 1.5 2.5 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF1313 PF07011.6 ETS86597.1 - 0.061 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) Sec66 PF09802.4 ETS86599.1 - 1.2e-70 236.8 0.6 1.4e-70 236.5 0.4 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF2458 PF10454.4 ETS86599.1 - 0.45 10.3 6.5 0.59 10.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) LcrG PF07216.7 ETS86599.1 - 0.83 9.7 4.6 2.8 8.0 0.1 2.5 1 1 1 2 2 2 0 LcrG protein Rho_Binding PF08912.6 ETS86599.1 - 1.9 8.8 9.5 1.9 8.8 1.8 2.4 1 1 1 2 2 2 0 Rho Binding RTC PF01137.16 ETS86600.1 - 9.3e-32 109.6 0.0 1.5e-31 108.9 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 ETS86600.1 - 1.3e-29 102.2 0.3 2.4e-29 101.3 0.2 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.5 ETS86601.1 - 1.1e-35 122.0 4.1 1.8e-35 121.3 2.8 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) OSTbeta PF15048.1 ETS86601.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Ribosomal_60s PF00428.14 ETS86601.1 - 3.4 8.1 0.0 3.4 8.1 0.0 3.3 3 1 0 3 3 3 0 60s Acidic ribosomal protein tRNA-synt_2d PF01409.15 ETS86602.1 - 4.2e-85 284.8 0.0 5.9e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 ETS86602.1 - 3.8e-06 26.6 0.0 1.3e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 ETS86602.1 - 2.4e-05 23.2 4.8 0.00018 20.3 0.1 3.4 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) Anp1 PF03452.9 ETS86605.1 - 3.8e-105 350.8 0.0 4.7e-105 350.5 0.0 1.0 1 0 0 1 1 1 1 Anp1 DUF3357 PF11837.3 ETS86605.1 - 0.02 14.7 0.3 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Glycos_transf_2 PF00535.21 ETS86605.1 - 0.032 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.21 ETS86606.1 - 2.7e-29 101.4 0.0 3.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS86606.1 - 0.00076 19.2 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 ETS86606.1 - 0.04 13.3 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 ETS86606.1 - 0.064 13.1 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 ETS86606.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 UEV domain bZIP_1 PF00170.16 ETS86607.1 - 5.2e-07 29.5 5.9 7.9e-07 28.9 4.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 ETS86607.1 - 1.6e-06 27.8 5.0 2.7e-06 27.1 3.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Mito_fiss_reg PF05308.6 ETS86607.1 - 0.012 14.9 6.9 0.023 14.0 4.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Phlebovirus_NSM PF07246.6 ETS86607.1 - 0.06 12.4 0.5 0.083 12.0 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CAP_N PF01213.14 ETS86607.1 - 6.6 5.9 7.8 11 5.2 5.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GMC_oxred_N PF00732.14 ETS86609.1 - 2.9e-65 220.3 0.0 3.7e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS86609.1 - 1.4e-30 106.4 0.1 2.9e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 ETS86609.1 - 5.5e-07 28.8 2.6 1.1e-05 24.5 1.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS86609.1 - 9e-07 28.0 0.3 0.0028 16.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 ETS86609.1 - 9.7e-06 24.7 0.5 1.6e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS86609.1 - 3.2e-05 23.8 0.3 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS86609.1 - 0.00081 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 ETS86609.1 - 0.0035 16.4 0.1 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 ETS86609.1 - 0.01 14.5 0.3 0.019 13.6 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 ETS86609.1 - 0.046 12.5 0.2 0.082 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 ETS86609.1 - 0.046 12.1 0.7 0.066 11.6 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 ETS86609.1 - 0.058 12.4 0.8 0.73 8.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain CVNH PF08881.5 ETS86610.1 - 0.0041 17.3 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 CVNH domain zf-UDP PF14569.1 ETS86611.1 - 0.82 9.4 6.8 1.7 8.4 4.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_3 PF07649.7 ETS86611.1 - 1.1 9.3 9.3 2.2 8.3 6.4 1.5 1 0 0 1 1 1 0 C1-like domain zf-RING_2 PF13639.1 ETS86611.1 - 1.6 8.6 11.2 2.6 7.9 7.8 1.3 1 0 0 1 1 1 0 Ring finger domain NinF PF05810.7 ETS86611.1 - 2 8.3 9.0 6.1 6.7 6.2 1.8 1 1 0 1 1 1 0 NinF protein zf-RING_5 PF14634.1 ETS86611.1 - 4.2 7.1 13.7 36 4.2 9.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS86611.1 - 5.8 6.8 13.4 6.7 6.6 5.7 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Lactamase_B_3 PF13483.1 ETS86612.1 - 7e-07 29.0 0.0 3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.27 ETS86613.1 - 5.4e-28 94.1 5.5 2.4e-06 26.4 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 ETS86613.1 - 2.5e-25 88.3 5.8 3.7e-10 39.8 0.5 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 ETS86613.1 - 3.7e-21 73.0 9.2 5e-05 22.8 0.2 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 ETS86613.1 - 2.4e-20 71.8 8.5 2.1e-07 30.4 0.0 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 ETS86613.1 - 5.5e-18 63.4 3.6 0.00034 19.8 0.0 4.4 4 0 0 4 4 4 4 EF hand ChaC PF04752.7 ETS86614.1 - 7.9e-38 130.1 0.0 1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Unstab_antitox PF09720.5 ETS86614.1 - 0.44 10.2 2.3 3.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Putative addiction module component RRM_1 PF00076.17 ETS86615.1 - 1.1e-23 82.6 0.0 1.4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS86615.1 - 1.3e-16 60.3 0.0 1.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS86615.1 - 2.2e-09 36.9 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.9 ETS86617.1 - 2.1e-41 141.2 0.1 2.4e-40 137.8 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 ETS86617.1 - 3.2e-13 49.2 0.0 8.4e-08 31.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.1 ETS86617.1 - 0.075 11.3 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ribosomal_S8 PF00410.14 ETS86618.1 - 0.002 17.9 0.1 3.5 7.4 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein S8 PASTA PF03793.14 ETS86618.1 - 0.013 15.1 3.2 2.5 7.8 0.1 3.7 4 0 0 4 4 4 0 PASTA domain DUF4224 PF13986.1 ETS86618.1 - 0.059 12.9 0.0 11 5.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) Arg_repressor PF01316.16 ETS86618.1 - 0.093 12.3 0.6 21 4.7 0.0 3.7 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Glutaredoxin PF00462.19 ETS86619.1 - 1.8e-15 56.6 0.3 4.6e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 ETS86619.1 - 0.0028 17.8 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_8 PF13905.1 ETS86619.1 - 0.02 15.0 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like WD40 PF00400.27 ETS86620.1 - 0.24 11.3 11.9 4.9 7.1 1.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat HlyIII PF03006.15 ETS86622.1 - 7.8e-58 195.4 15.0 9.2e-58 195.2 10.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMA7 PF09072.5 ETS86623.1 - 6.6e-25 87.3 15.7 7.3e-25 87.2 10.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Nefa_Nip30_N PF10187.4 ETS86623.1 - 0.012 15.7 0.4 0.015 15.4 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SPT6_acidic PF14632.1 ETS86623.1 - 0.032 14.4 1.0 0.041 14.0 0.7 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Pkinase PF00069.20 ETS86624.1 - 4.6e-53 180.0 0.1 6.3e-53 179.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86624.1 - 2.6e-23 82.4 0.1 7.9e-23 80.8 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS86624.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 ETS86624.1 - 0.057 12.1 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 ETS86625.1 - 1.1e-59 201.7 0.0 1.4e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86625.1 - 1.3e-30 106.3 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS86625.1 - 0.00018 20.5 0.0 0.00036 19.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETS86625.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS86625.1 - 0.0043 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peripla_BP_2 PF01497.13 ETS86625.1 - 0.0092 15.1 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein YrbL-PhoP_reg PF10707.4 ETS86625.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 ETS86625.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.27 ETS86626.1 - 2e-07 30.6 0.0 0.45 10.4 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat NACHT PF05729.7 ETS86626.1 - 1.5e-05 24.7 0.0 4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 ETS86626.1 - 5.6e-05 22.8 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 ETS86626.1 - 0.00025 20.3 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 ETS86626.1 - 0.0027 17.5 0.0 0.009 15.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 ETS86626.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 ETS86626.1 - 0.033 13.9 0.1 0.18 11.5 0.1 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA_22 PF13401.1 ETS86626.1 - 0.045 13.9 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 ETS86627.1 - 8.3e-13 47.8 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 ETS86627.1 - 0.012 15.1 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Fructosamin_kin PF03881.9 ETS86628.1 - 1.3e-41 142.4 0.0 1.7e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 ETS86628.1 - 3e-08 33.6 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 ETS86629.1 - 4.8e-12 45.3 3.1 1.4e-11 43.7 2.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS86629.1 - 0.044 14.1 2.5 0.054 13.8 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS86629.1 - 0.065 13.5 2.6 0.071 13.4 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger FUSC PF04632.7 ETS86629.1 - 0.13 10.6 2.7 0.1 11.0 0.8 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family LamB_YcsF PF03746.11 ETS86630.1 - 5.5e-68 228.6 0.0 6.3e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family adh_short_C2 PF13561.1 ETS86631.1 - 9.7e-26 91.0 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS86631.1 - 9.5e-24 84.1 1.5 1.9e-23 83.1 1.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86631.1 - 1.3e-08 34.7 0.8 1.2e-07 31.5 0.5 2.2 1 1 0 1 1 1 1 KR domain ThiF PF00899.16 ETS86631.1 - 0.026 14.3 2.8 0.31 10.8 0.6 2.4 2 0 0 2 2 2 0 ThiF family Cyclase PF04199.8 ETS86632.1 - 3.4e-31 108.2 0.1 4.9e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase Gln-synt_C PF00120.19 ETS86634.1 - 2.5e-59 200.5 0.0 4e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Aa_trans PF01490.13 ETS86636.1 - 3.7e-28 98.1 37.2 4.7e-28 97.7 25.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 ETS86636.1 - 1.3e-05 23.9 49.1 0.00081 18.0 34.0 2.0 1 1 0 1 1 1 1 Amino acid permease GP41 PF00517.12 ETS86636.1 - 8.4 5.8 9.0 25 4.3 1.0 3.3 3 0 0 3 3 3 0 Retroviral envelope protein Acetyltransf_1 PF00583.19 ETS86637.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS86637.1 - 4.8e-08 33.0 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 ETS86637.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_10 PF13673.1 ETS86637.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS86637.1 - 0.05 13.3 0.0 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 FR47-like protein AAA PF00004.24 ETS86639.1 - 4.5e-19 68.9 0.0 1.4e-17 64.0 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS86639.1 - 7.5e-06 26.1 1.1 0.0063 16.6 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 ETS86639.1 - 0.00027 20.6 0.0 0.00091 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS86639.1 - 0.00043 21.0 0.3 0.012 16.4 0.0 3.0 3 1 0 4 4 2 1 AAA domain AAA_16 PF13191.1 ETS86639.1 - 0.00086 19.3 0.5 0.0046 16.9 0.3 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 ETS86639.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETS86639.1 - 0.0018 18.5 0.2 0.044 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 ETS86639.1 - 0.0026 17.6 0.1 0.019 14.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 ETS86639.1 - 0.0061 16.2 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 ETS86639.1 - 0.023 14.1 0.0 0.072 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 ETS86639.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 ETS86639.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Zot PF05707.7 ETS86639.1 - 0.042 13.3 0.9 0.37 10.2 0.0 2.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 ETS86639.1 - 0.097 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 ETS86639.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 ETS86640.1 - 0.0083 15.3 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Cupin_2 PF07883.6 ETS86641.1 - 7e-09 35.0 0.0 1.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 ETS86641.1 - 0.002 17.4 0.1 0.0053 16.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 ETS86641.1 - 0.034 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Imm45 PF15603.1 ETS86641.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 45 FAD_binding_3 PF01494.14 ETS86642.1 - 8.4e-22 77.6 0.3 1.6e-21 76.8 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 ETS86642.1 - 8.6e-13 48.1 0.0 2e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 ETS86642.1 - 2.5e-09 36.5 0.7 1.8e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86642.1 - 2.5e-07 30.5 1.3 8.4e-07 28.9 0.5 2.3 2 1 1 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS86642.1 - 5.5e-06 26.3 0.2 1e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS86642.1 - 1.1e-05 24.5 0.3 2.6e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS86642.1 - 0.00032 19.7 0.7 0.0013 17.7 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 ETS86642.1 - 0.0025 16.7 0.2 0.0043 15.9 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 ETS86642.1 - 0.003 17.9 0.1 0.0085 16.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS86642.1 - 0.0059 16.6 1.6 0.015 15.3 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS86642.1 - 0.015 14.3 0.1 0.027 13.5 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 ETS86642.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 ETS86642.1 - 0.033 13.7 0.2 0.085 12.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 ETS86642.1 - 0.043 12.2 0.1 0.071 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 ETS86642.1 - 0.066 12.9 5.0 0.035 13.8 0.8 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 ETS86642.1 - 0.069 11.7 0.1 0.25 9.9 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 ETS86643.1 - 1.2e-24 87.0 1.2 1.8e-24 86.5 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86643.1 - 7.5e-20 71.7 0.1 8.6e-20 71.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86643.1 - 1.1e-10 41.4 0.4 1.6e-10 40.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86643.1 - 0.0024 17.3 0.1 0.01 15.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_PPF PF02916.10 ETS86643.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor MFS_1 PF07690.11 ETS86644.1 - 1.4e-34 119.3 31.8 1.4e-34 119.3 22.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86644.1 - 4.4e-10 38.7 20.8 4.4e-10 38.7 14.4 3.7 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 ETS86644.1 - 0.0016 16.7 4.3 0.0093 14.2 3.2 1.9 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 ETS86645.1 - 8.6e-14 51.0 0.2 2.4e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 ETS86645.1 - 1.2e-12 47.3 4.4 1.4e-05 25.1 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 ETS86645.1 - 2.4e-05 24.1 10.5 2.4e-05 24.1 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 ETS86645.1 - 2.9e-05 24.1 4.2 0.00076 19.6 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS86645.1 - 0.00021 21.3 18.7 0.0012 19.0 0.1 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 ETS86645.1 - 0.14 12.4 4.3 5.2 7.4 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Abhydrolase_6 PF12697.2 ETS86646.1 - 5.5e-22 78.7 2.7 9.5e-22 77.9 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS86646.1 - 4.3e-12 46.0 0.1 9.3e-11 41.6 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS86646.1 - 8.9e-10 38.5 0.1 5.6e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS86646.1 - 1.8e-06 27.6 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 ETS86646.1 - 0.0071 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 ETS86646.1 - 0.014 14.7 0.0 0.13 11.5 0.0 2.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.15 ETS86646.1 - 0.053 13.7 0.4 0.66 10.1 0.1 2.2 2 0 0 2 2 2 0 Thioesterase domain RtxA PF07634.6 ETS86646.1 - 0.067 13.4 1.0 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 RtxA repeat DUF2048 PF09752.4 ETS86646.1 - 0.21 10.3 0.5 0.44 9.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) dCMP_cyt_deam_1 PF00383.17 ETS86648.1 - 2.5e-14 52.7 0.1 3.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 ETS86648.1 - 1.9e-08 34.3 1.3 9.7e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 ETS86648.1 - 0.008 15.5 0.7 0.47 9.8 0.5 2.1 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases ELMO_CED12 PF04727.8 ETS86649.1 - 2.6e-48 163.7 0.3 5.1e-48 162.8 0.2 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 ETS86649.1 - 0.00026 20.7 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) zf-GRF PF06839.7 ETS86650.1 - 7.5e-08 32.1 4.8 1.5e-07 31.1 3.4 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF515 PF04415.7 ETS86650.1 - 3.8 5.6 7.7 0.17 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF515) GMC_oxred_N PF00732.14 ETS86651.1 - 2.5e-30 105.6 0.0 7.7e-29 100.7 0.0 2.7 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS86651.1 - 8.9e-28 97.3 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 ETS86651.1 - 2.5e-05 24.2 0.1 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS86651.1 - 0.00038 19.4 1.5 0.11 11.3 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 ETS86651.1 - 0.0025 17.9 0.2 0.32 11.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS86651.1 - 0.0038 17.2 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain PrpR_N PF06506.6 ETS86651.1 - 0.069 12.5 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Propionate catabolism activator HI0933_like PF03486.9 ETS86651.1 - 0.076 11.4 0.7 0.21 10.0 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS86651.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS86651.1 - 0.19 10.5 2.4 0.42 9.3 1.2 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 ETS86652.1 - 5.7e-42 143.9 0.0 7.1e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86652.1 - 3.1e-06 27.1 0.1 9.1e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS86652.1 - 0.00022 21.1 0.1 0.0041 17.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS86652.1 - 0.00035 19.5 0.0 0.00098 18.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 ETS86652.1 - 0.00061 18.9 0.0 0.0031 16.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS86652.1 - 0.001 19.1 0.1 0.0029 17.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS86652.1 - 0.0011 18.7 0.1 0.0038 17.0 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.16 ETS86652.1 - 0.0098 15.7 0.0 0.069 12.9 0.0 2.1 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 ETS86652.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 ETS86652.1 - 0.027 13.0 0.0 0.75 8.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 ETS86652.1 - 0.032 13.8 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 ETS86652.1 - 0.044 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 ETS86652.1 - 0.051 13.9 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS86652.1 - 0.099 12.0 0.1 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 ETS86652.1 - 0.1 11.4 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 ETS86652.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 ETS86653.1 - 6.8e-52 176.5 15.7 8.3e-52 176.2 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86653.1 - 2.4e-17 62.7 33.3 5.2e-15 55.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86654.1 - 2e-06 26.6 1.6 2.3e-06 26.4 1.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86654.1 - 0.02 13.6 0.3 0.021 13.5 0.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Csm1 PF12539.3 ETS86654.1 - 0.074 13.5 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 Ribonuc_L-PSP PF01042.16 ETS86655.1 - 2.8e-17 62.6 0.0 3e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 ETS86656.1 - 3.8e-27 94.7 0.2 5.6e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86656.1 - 2e-10 40.3 7.9 5.5e-10 39.0 5.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.1 ETS86658.1 - 0.00075 19.6 0.0 0.0034 17.5 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS86658.1 - 0.0014 18.8 0.6 0.055 13.8 0.2 3.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS86658.1 - 0.019 15.4 1.6 0.21 12.1 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) peroxidase PF00141.18 ETS86659.1 - 1.2e-21 77.2 1.3 1.3e-21 77.1 0.2 1.6 2 0 0 2 2 2 1 Peroxidase SprB PF13573.1 ETS86659.1 - 0.5 10.0 4.1 0.27 10.8 0.5 2.3 2 0 0 2 2 2 0 SprB repeat SGL PF08450.7 ETS86660.1 - 2e-08 33.9 0.1 2.2e-07 30.5 0.1 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 ETS86660.1 - 0.11 12.4 6.6 3.2 7.8 0.1 4.0 3 1 0 3 3 3 0 NHL repeat DUF839 PF05787.8 ETS86660.1 - 0.12 11.2 0.2 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) SnoaL_4 PF13577.1 ETS86661.1 - 4.9e-10 39.3 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.17 ETS86662.1 - 8.5e-31 106.9 0.0 8.2e-19 67.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 dDENN PF03455.14 ETS86662.1 - 0.0067 16.4 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 dDENN domain Fungal_trans PF04082.13 ETS86663.1 - 5.2e-12 45.2 0.4 7.7e-12 44.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 ETS86664.1 - 1.4e-27 96.4 0.0 2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS86664.1 - 7.1e-06 26.5 0.0 1.7e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86664.1 - 0.00017 21.2 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86664.1 - 0.00048 20.5 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86664.1 - 0.001 19.3 0.0 0.022 15.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 ETS86664.1 - 0.0052 16.1 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS86664.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HTH_24 PF13412.1 ETS86664.1 - 0.031 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ketoacyl-synt PF00109.21 ETS86665.1 - 1.5e-70 237.6 0.0 3.7e-70 236.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 ETS86665.1 - 1.6e-64 217.8 0.0 3.6e-64 216.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 ETS86665.1 - 2.5e-55 186.9 0.7 2.5e-54 183.6 0.1 2.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 ETS86665.1 - 1.5e-52 178.9 0.0 3.2e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 ETS86665.1 - 4.1e-44 150.4 0.3 4.1e-44 150.4 0.2 3.9 3 1 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS86665.1 - 5.1e-33 113.4 0.1 1.1e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS86665.1 - 1.9e-19 69.9 0.0 8.8e-18 64.6 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS86665.1 - 3.4e-13 49.2 0.0 6.9e-12 45.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 ETS86665.1 - 4.8e-11 43.0 0.0 4e-09 36.8 0.0 3.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86665.1 - 4.9e-11 42.6 0.0 2.1e-10 40.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86665.1 - 4.5e-10 39.3 0.0 1.8e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86665.1 - 5.7e-10 39.7 0.0 7.2e-09 36.2 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.20 ETS86665.1 - 6.5e-08 32.7 0.1 1.7e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 ETS86665.1 - 7.9e-07 28.0 0.0 1.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.7 ETS86665.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 ETS86665.1 - 0.00028 20.0 0.0 0.00062 18.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 ETS86665.1 - 0.00069 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 ETS86665.1 - 0.001 19.1 0.0 0.01 15.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 ETS86665.1 - 0.0033 16.4 0.5 0.0072 15.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain NAD_binding_3 PF03447.11 ETS86665.1 - 0.012 16.0 0.2 0.93 9.9 0.0 3.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Cadherin_2 PF08266.7 ETS86665.1 - 0.033 13.7 0.1 0.098 12.2 0.1 1.8 1 0 0 1 1 1 0 Cadherin-like FAD_binding_4 PF01565.18 ETS86666.1 - 2e-25 88.8 0.3 3.8e-25 87.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 ETS86666.1 - 2.1e-05 24.3 0.1 5.6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.14 ETS86667.1 - 5.6e-48 163.5 0.1 7.6e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS86667.1 - 8.1e-35 120.2 0.0 1.5e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 ETS86667.1 - 1.1e-05 24.5 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 ETS86667.1 - 7.7e-05 21.7 0.0 0.019 13.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS86667.1 - 0.00025 20.0 0.1 0.34 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 ETS86667.1 - 0.0017 18.3 0.2 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS86667.1 - 0.01 14.4 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF3638 PF12340.3 ETS86668.1 - 5.5e-92 306.8 1.9 3.2e-91 304.3 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 ETS86668.1 - 3.3e-16 58.0 0.7 6.8e-16 57.0 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) HSCB_C PF07743.8 ETS86669.1 - 6.3e-19 68.2 5.2 6.3e-19 68.2 3.6 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 ETS86669.1 - 1.5e-07 30.9 0.1 4.6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain LRR_4 PF12799.2 ETS86670.1 - 0.0069 15.9 3.9 0.042 13.4 0.8 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS86670.1 - 0.024 14.3 6.1 0.034 13.8 0.5 2.9 4 0 0 4 4 4 0 Leucine rich repeat SoxD PF04267.7 ETS86670.1 - 0.036 13.9 1.6 0.087 12.6 1.1 1.6 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family LRR_6 PF13516.1 ETS86670.1 - 3.7 7.9 10.5 7.7 6.9 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich repeat PAN_4 PF14295.1 ETS86672.1 - 2.5e-06 27.0 0.7 1.3e-05 24.7 0.5 2.3 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.21 ETS86672.1 - 2.5e-05 23.9 0.1 5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 PAN domain MFS_1 PF07690.11 ETS86673.1 - 1.6e-33 115.8 35.2 1.6e-33 115.8 24.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily BCS1_N PF08740.6 ETS86674.1 - 3.2e-42 144.2 0.1 4.1e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 ETS86674.1 - 2.8e-18 66.4 0.0 4.5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS86674.1 - 1.9e-05 25.4 0.0 5e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS86674.1 - 0.00026 20.8 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 ETS86674.1 - 0.00049 19.5 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS86674.1 - 0.00077 19.4 0.2 0.0047 16.9 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 ETS86674.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS86674.1 - 0.0018 18.3 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 ETS86674.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 ETS86674.1 - 0.006 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 ETS86674.1 - 0.008 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 ETS86674.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 ETS86674.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 ETS86674.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS86674.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Viral_helicase1 PF01443.13 ETS86674.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 ETS86674.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 ETS86674.1 - 0.083 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 ETS86674.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 ETS86674.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS86674.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 ETS86674.1 - 0.099 12.3 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 ETS86674.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase Miro PF08477.8 ETS86674.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Rad17 PF03215.10 ETS86674.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Iso_dh PF00180.15 ETS86675.1 - 1.1e-80 271.2 0.0 1.2e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1964 PF09244.5 ETS86675.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) AMP-binding PF00501.23 ETS86676.1 - 5.4e-83 278.6 0.0 7e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS86676.1 - 5.3e-13 49.7 0.0 1.9e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro_7 PF00840.15 ETS86677.1 - 2.2e-206 685.3 26.1 2.6e-206 685.0 18.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3086 PF11285.3 ETS86678.1 - 0.00025 19.9 0.0 0.00064 18.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3086) TPR_9 PF13371.1 ETS86678.1 - 0.012 15.4 0.1 0.051 13.4 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS86679.1 - 5e-39 133.9 38.8 5.1e-38 130.6 15.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 ETS86679.1 - 7.3e-07 28.3 0.3 4.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86679.1 - 2.9e-06 27.0 10.2 5.6e-06 26.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 ETS86680.1 - 1e-17 64.0 1.1 4e-17 62.0 0.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 ETS86680.1 - 0.0019 16.4 2.8 0.11 10.6 0.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_3 PF13385.1 ETS86680.1 - 0.11 12.7 12.1 0.25 11.5 8.4 1.8 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Peptidase_M20 PF01546.23 ETS86681.1 - 1.6e-05 24.4 7.7 3.4e-05 23.4 5.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS86681.1 - 0.00036 20.2 0.1 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 ETS86682.1 - 7.4e-35 120.2 27.9 1e-34 119.8 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 ETS86682.1 - 0.5 10.7 2.2 0.46 10.9 0.1 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MAPEG PF01124.13 ETS86682.1 - 9.7 5.8 14.4 0.47 10.0 4.3 2.9 2 1 1 3 3 3 0 MAPEG family DOMON PF03351.12 ETS86683.1 - 7.8e-09 35.5 1.1 8.1e-08 32.2 0.2 2.5 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 ETS86683.1 - 2.2e-06 27.1 7.8 2.2e-06 27.1 5.4 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 ETS86683.1 - 3.9e-05 23.4 14.9 0.00011 22.0 10.3 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 MarC PF01914.12 ETS86683.1 - 1.3 8.0 11.6 0.18 10.9 2.1 2.4 1 1 1 2 2 2 0 MarC family integral membrane protein DUF373 PF04123.8 ETS86683.1 - 2.6 6.9 10.9 4.1 6.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) RAP1 PF07218.6 ETS86683.1 - 7.1 4.5 17.3 9.5 4.1 12.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 ETS86684.1 - 1.1e-64 218.0 0.0 1.4e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86684.1 - 3.5e-30 104.9 0.0 4.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETS86684.1 - 0.0088 16.5 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS86684.1 - 0.03 13.2 0.0 0.065 12.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like MHCassoc_trimer PF08831.5 ETS86684.1 - 0.072 12.9 0.5 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain APH PF01636.18 ETS86684.1 - 0.16 11.6 0.3 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH PF00169.24 ETS86685.1 - 3.5e-05 23.9 0.0 0.00077 19.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 ETS86685.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PP2C_2 PF13672.1 ETS86686.1 - 3.7e-05 23.2 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 ETS86686.1 - 0.0027 17.4 0.0 0.013 15.2 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.7 ETS86687.1 - 6.7e-26 90.3 0.3 1.6e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 Fcf1 Glypican PF01153.14 ETS86687.1 - 8.7 4.8 8.3 13 4.2 5.8 1.2 1 0 0 1 1 1 0 Glypican DUF726 PF05277.7 ETS86688.1 - 6e-129 429.8 1.6 8.1e-129 429.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 ETS86688.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 ETS86688.1 - 0.035 13.8 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family SKG6 PF08693.5 ETS86689.1 - 9.2e-05 21.6 1.3 9.2e-05 21.6 0.9 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain AJAP1_PANP_C PF15298.1 ETS86689.1 - 0.00014 21.7 0.8 0.00014 21.7 0.5 2.6 3 0 0 3 3 3 1 AJAP1/PANP C-terminus Herpes_gE PF02480.11 ETS86689.1 - 0.0024 16.2 0.1 0.0043 15.3 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E VSP PF03302.8 ETS86689.1 - 0.0049 15.5 5.5 0.0082 14.8 3.8 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DAG1 PF05454.6 ETS86689.1 - 0.12 11.5 0.1 0.55 9.3 0.0 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF846 PF05832.7 ETS86690.1 - 2.6e-53 179.5 7.9 3.1e-53 179.3 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Cu2_monoox_C PF03712.10 ETS86691.1 - 0.04 13.2 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain zf-CCHC_4 PF14392.1 ETS86691.1 - 7.2 6.3 7.1 28 4.4 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle MIS13 PF08202.6 ETS86693.1 - 0.0071 15.4 0.6 0.0072 15.4 0.4 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Dynamitin PF04912.9 ETS86693.1 - 0.0087 14.9 0.7 0.011 14.6 0.5 1.2 1 0 0 1 1 1 1 Dynamitin CR6_interact PF10147.4 ETS86693.1 - 0.0087 15.4 1.6 0.01 15.1 1.1 1.0 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Selenoprotein_S PF06936.6 ETS86693.1 - 0.0097 15.4 0.6 0.011 15.2 0.4 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Cortex-I_coil PF09304.5 ETS86693.1 - 0.027 14.5 2.3 0.034 14.2 1.6 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil YedD PF13987.1 ETS86693.1 - 0.028 13.9 0.1 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 YedD-like protein NPV_P10 PF05531.7 ETS86693.1 - 0.04 14.1 0.7 0.053 13.7 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.3 ETS86693.1 - 0.042 13.5 0.6 0.042 13.5 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) OmpH PF03938.9 ETS86693.1 - 0.045 13.6 0.7 0.046 13.6 0.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.1 ETS86693.1 - 0.049 13.6 2.2 0.057 13.4 1.6 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MitMem_reg PF13012.1 ETS86693.1 - 0.091 12.8 0.5 0.11 12.5 0.4 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF2968 PF11180.3 ETS86693.1 - 0.17 11.2 3.6 0.13 11.6 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) p450 PF00067.17 ETS86694.1 - 8.5e-48 163.0 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KaiC PF06745.8 ETS86694.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC NmrA PF05368.8 ETS86695.1 - 3.2e-12 46.2 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS86695.1 - 1.1e-09 38.5 0.0 3.4e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 ETS86695.1 - 0.00046 20.1 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 ETS86695.1 - 0.00087 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 ETS86695.1 - 0.0024 16.6 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 ETS86695.1 - 0.0071 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 ETS86695.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 ETS86695.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 ETS86695.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.5 2 0 0 2 2 2 0 KR domain Gp_dh_N PF00044.19 ETS86695.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ApbA PF02558.11 ETS86695.1 - 0.046 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 ETS86695.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 ETS86695.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 ETS86695.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 ThiF family CtnDOT_TraJ PF07863.6 ETS86696.1 - 3.4 8.1 4.3 42 4.6 0.5 3.2 2 1 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon IU_nuc_hydro PF01156.14 ETS86697.1 - 9.3e-52 176.1 0.0 1.3e-50 172.4 0.0 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 ETS86698.1 - 8.4e-16 57.2 0.2 1.1e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain CHRD PF07452.7 ETS86699.1 - 0.022 15.3 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 CHRD domain Alpha-amylase PF00128.19 ETS86700.1 - 3.9e-69 233.4 1.6 5.7e-69 232.9 1.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 ETS86700.1 - 5e-33 112.5 0.9 1.5e-32 111.0 0.6 1.9 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 ETS86700.1 - 2.9e-14 52.9 1.2 1.6e-13 50.5 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF1966) DUF3499 PF12005.3 ETS86700.1 - 0.025 14.7 0.8 2 8.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Fungal_trans PF04082.13 ETS86701.1 - 2.5e-16 59.3 0.2 4.5e-16 58.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86701.1 - 1.8e-07 30.9 9.4 2.8e-07 30.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 ETS86701.1 - 1.1 9.4 7.0 2.3 8.4 4.8 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Cu-oxidase_3 PF07732.10 ETS86702.1 - 1e-43 147.8 1.9 1e-43 147.8 1.3 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS86702.1 - 7.2e-38 129.2 7.2 1e-35 122.2 0.3 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS86702.1 - 5.2e-26 91.4 0.0 6.3e-25 87.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Glutaredoxin PF00462.19 ETS86703.1 - 1.5e-17 63.2 0.0 1.9e-16 59.7 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 ETS86703.1 - 2.9e-13 49.3 0.0 6.7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETS86703.1 - 0.046 13.8 0.0 4.5 7.4 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like HET PF06985.6 ETS86704.1 - 1.2e-35 122.7 0.1 2.6e-35 121.6 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86705.1 - 9e-35 119.8 0.5 1.8e-34 118.8 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 ETS86706.1 - 0.027 13.0 0.0 0.16 10.5 0.0 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain CYSTM PF12734.2 ETS86707.1 - 0.063 13.3 10.7 0.063 13.3 7.4 4.4 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance PAT1 PF09770.4 ETS86707.1 - 8.6 4.4 11.5 8.4 4.4 8.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_9 PF14604.1 ETS86708.1 - 5.1e-29 99.6 10.6 1.3e-14 53.4 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 ETS86708.1 - 7.8e-25 86.0 3.9 1.4e-12 46.7 0.4 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 ETS86708.1 - 3.1e-16 58.6 0.0 4e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 ETS86708.1 - 3.1e-12 46.4 0.0 5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-H2C2_2 PF13465.1 ETS86709.1 - 4.6e-07 29.7 8.8 3.6e-06 26.9 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS86709.1 - 4.4e-05 23.5 4.1 0.00063 19.9 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS86709.1 - 0.00019 21.5 0.3 0.00019 21.5 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 ETS86709.1 - 0.72 10.0 3.9 4.4 7.5 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fe_hyd_lg_C PF02906.9 ETS86711.1 - 2.7e-63 213.9 0.0 6.7e-63 212.6 0.0 1.7 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain U1snRNP70_N PF12220.3 ETS86712.1 - 0.37 11.1 9.0 0.065 13.5 2.6 2.4 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PAT1 PF09770.4 ETS86712.1 - 1.2 7.3 6.7 1.5 6.9 4.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 ETS86715.1 - 3.3e-70 236.2 0.0 4.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86715.1 - 1.1e-30 106.6 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 ETS86715.1 - 1.2e-12 48.1 2.6 1.2e-12 48.1 1.8 2.6 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 ETS86715.1 - 3.2e-10 39.4 0.0 8.1e-10 38.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 ETS86715.1 - 3.9e-05 23.4 0.0 0.00016 21.4 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 ETS86715.1 - 0.056 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 ETS86715.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HET PF06985.6 ETS86716.1 - 1.4e-06 28.5 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_sub_h PF10775.4 ETS86717.1 - 2e-25 88.2 0.6 3.3e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 ETS86717.1 - 0.017 15.0 0.1 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF3278 PF11683.3 ETS86718.1 - 0.15 12.0 8.2 0.15 12.0 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) PgaD PF13994.1 ETS86718.1 - 5.9 6.3 12.6 12 5.3 8.7 1.5 1 0 0 1 1 1 0 PgaD-like protein Lipase_GDSL_2 PF13472.1 ETS86719.1 - 3.3e-19 69.7 0.0 3.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS86719.1 - 3.3e-10 40.2 0.0 6e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.22 ETS86720.1 - 1.4e-12 47.8 0.1 2e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.4 ETS86720.1 - 0.00034 20.0 0.8 0.00072 18.9 0.3 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 peroxidase PF00141.18 ETS86722.1 - 1.6e-50 171.7 0.0 2.3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase CPSase_L_D2 PF02786.12 ETS86723.1 - 4.8e-109 362.5 0.0 2e-84 282.1 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 ETS86723.1 - 4.2e-40 136.3 0.0 9.2e-40 135.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 ETS86723.1 - 1.1e-39 136.0 0.1 1e-22 80.7 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 ETS86723.1 - 1.6e-30 105.4 0.0 2.2e-15 56.7 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 ETS86723.1 - 3.7e-27 94.9 0.0 4.7e-11 41.9 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 ETS86723.1 - 8.9e-21 73.9 0.2 2.2e-09 36.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS86723.1 - 2.4e-17 63.0 0.3 4.6e-08 32.6 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 ETS86723.1 - 1.1e-08 34.8 0.0 3.5e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 ETS86723.1 - 9.9e-07 28.7 0.1 0.045 13.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 ETS86723.1 - 5.6e-06 26.0 0.1 0.13 11.8 0.1 2.9 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 ETS86723.1 - 0.0021 17.3 0.0 0.33 10.1 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain EAP30 PF04157.11 ETS86723.1 - 0.058 12.5 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family MGS PF02142.17 ETS86723.1 - 0.062 13.2 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 MGS-like domain Aldo_ket_red PF00248.16 ETS86724.1 - 3.2e-41 141.0 0.0 3.5e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidase PF01425.16 ETS86725.1 - 2.5e-56 191.3 0.2 5.4e-56 190.3 0.1 1.6 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 ETS86726.1 - 1.1e-41 142.7 0.0 1.3e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86726.1 - 1.2e-06 28.2 9.4 1.2e-06 28.2 6.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 ETS86727.1 - 4.7e-12 45.5 0.1 4.7e-12 45.5 0.1 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein p450 PF00067.17 ETS86728.1 - 3e-48 164.5 0.0 4.1e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 ETS86729.1 - 9.6e-37 126.4 42.1 9.6e-37 126.4 29.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 ETS86729.1 - 1e-09 37.1 13.7 1.5e-09 36.6 9.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 ETS86729.1 - 1.7e-05 23.6 17.1 0.0002 20.0 5.7 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter ATP-grasp_4 PF13535.1 ETS86731.1 - 1.8e-23 83.1 0.0 2.4e-21 76.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS86731.1 - 4.5e-07 28.9 0.0 2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 ETS86731.1 - 6.6e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 ETS86731.1 - 0.00018 20.9 0.0 0.00075 18.9 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 ETS86731.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.11 ETS86731.1 - 0.052 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.14 ETS86731.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FAD_binding_4 PF01565.18 ETS86733.1 - 1.2e-20 73.3 5.7 1.2e-20 73.3 4.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS86733.1 - 1.8e-13 50.1 0.1 3.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_5 PF13857.1 ETS86734.1 - 1.9e-17 62.8 0.1 1.7e-06 28.0 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS86734.1 - 6.4e-16 58.4 0.0 1.5e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86734.1 - 6.4e-15 54.1 0.0 3e-07 29.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 ETS86734.1 - 2e-13 50.4 0.0 4.9e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86734.1 - 7.2e-10 38.1 0.0 0.0042 17.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2_4 PF13894.1 ETS86734.1 - 0.073 13.4 11.5 1.5 9.3 0.3 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 ETS86734.1 - 0.093 11.9 1.2 12 5.2 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 ETS86734.1 - 0.44 10.6 2.0 51 4.1 0.0 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HET PF06985.6 ETS86735.1 - 2.9e-21 76.0 12.0 4.2e-19 69.0 8.3 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 ETS86736.1 - 0.078 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 ETS86737.1 - 0.00019 21.5 0.0 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS86737.1 - 0.01 16.3 0.2 0.55 10.8 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS86737.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NPL4 PF05021.10 ETS86739.1 - 3.9e-120 400.6 0.0 4.9e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 ETS86739.1 - 2.8e-67 224.9 0.1 5.1e-67 224.1 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 ETS86739.1 - 3.8e-05 23.8 0.0 0.00015 21.9 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 PWWP PF00855.12 ETS86740.1 - 7.3e-12 45.3 0.0 7.3e-12 45.3 0.0 2.6 2 1 0 2 2 2 1 PWWP domain Sec63 PF02889.11 ETS86741.1 - 1.9e-189 628.5 1.3 9.4e-104 346.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 ETS86741.1 - 3.2e-51 173.1 0.0 1.5e-30 105.9 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 ETS86741.1 - 2e-15 57.1 0.0 5.2e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 ETS86741.1 - 5.1e-10 39.0 0.0 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS86741.1 - 1.1e-06 28.7 0.3 0.0028 17.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 ETS86741.1 - 5.3e-05 22.5 0.0 0.013 14.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 ETS86741.1 - 0.0009 18.7 0.0 1.2 8.5 0.0 3.5 3 0 0 3 3 3 2 AAA-like domain T2SE PF00437.15 ETS86741.1 - 0.0011 17.9 0.0 0.51 9.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 ETS86741.1 - 0.0038 16.9 0.1 0.87 9.3 0.0 3.3 4 0 0 4 4 4 1 Part of AAA domain AAA PF00004.24 ETS86743.1 - 6.2e-16 58.8 0.1 3.1e-15 56.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 ETS86743.1 - 5.2e-14 52.2 0.1 1.1e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 ETS86743.1 - 3.8e-12 45.6 0.1 1.1e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 ETS86743.1 - 5.4e-12 45.5 0.2 1.9e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 ETS86743.1 - 1.7e-07 31.4 0.3 0.00033 20.8 0.0 3.5 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS86743.1 - 2.3e-07 30.1 0.0 1.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 ETS86743.1 - 1.3e-05 24.8 0.0 4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 ETS86743.1 - 2.4e-05 24.0 0.0 4.9e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS86743.1 - 4.1e-05 23.6 0.0 0.0012 18.8 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 ETS86743.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 ETS86743.1 - 0.00018 20.7 0.0 0.0075 15.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 ETS86743.1 - 0.0002 20.9 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 ETS86743.1 - 0.0015 19.3 0.0 0.0037 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETS86743.1 - 0.002 17.1 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 ETS86743.1 - 0.0024 17.2 0.0 0.013 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 ETS86743.1 - 0.003 17.1 0.2 0.0073 15.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 ETS86743.1 - 0.0035 16.3 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 ETS86743.1 - 0.0094 14.7 0.0 0.42 9.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 ETS86743.1 - 0.011 15.2 0.2 0.039 13.4 0.0 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 ETS86743.1 - 0.013 15.2 0.2 0.12 12.0 0.1 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 ETS86743.1 - 0.013 15.8 0.0 0.038 14.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETS86743.1 - 0.022 14.3 0.1 0.28 10.7 0.0 2.7 2 2 2 4 4 4 0 AAA domain AAA_28 PF13521.1 ETS86743.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 ETS86743.1 - 0.052 13.3 0.1 0.31 10.8 0.0 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 ETS86743.1 - 0.055 13.0 0.0 0.27 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 ETS86743.1 - 0.065 12.0 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 ETS86743.1 - 0.077 12.6 0.1 0.42 10.2 0.0 2.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 ETS86743.1 - 0.088 12.2 0.1 1.4 8.3 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 ETS86743.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 ETS86743.1 - 0.093 12.2 0.1 2 7.8 0.0 2.7 4 0 0 4 4 4 0 DEAD/DEAH box helicase DUF2417 PF10329.4 ETS86744.1 - 1.6e-79 266.6 4.8 2.1e-79 266.1 3.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 ETS86744.1 - 1.2e-10 41.6 0.3 2.1e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS86744.1 - 9.2e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS86746.1 - 2.5e-90 303.7 0.0 1.5e-80 271.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS86746.1 - 3.3e-08 33.3 0.0 6.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS86746.1 - 0.03 13.5 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS86746.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UQ_con PF00179.21 ETS86748.1 - 4.4e-42 142.8 0.0 3.6e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 ETS86748.1 - 8.6e-05 22.3 0.0 0.57 10.0 0.0 2.7 2 1 0 2 2 2 2 RWD domain UEV PF05743.8 ETS86748.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 UEV domain 3Beta_HSD PF01073.14 ETS86749.1 - 8.8e-64 214.8 0.0 1.1e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS86749.1 - 2.6e-29 102.3 0.2 3.9e-29 101.7 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS86749.1 - 6.6e-14 51.4 0.7 1.2e-11 44.0 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 ETS86749.1 - 4.4e-12 45.4 0.4 6.4e-12 44.9 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 ETS86749.1 - 4.3e-10 39.8 0.3 6.2e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS86749.1 - 1.3e-06 27.6 0.0 5.1e-06 25.5 0.1 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS86749.1 - 2.8e-06 27.3 0.8 5.8e-06 26.3 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 ETS86749.1 - 1.9e-05 24.0 0.1 2.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 ETS86749.1 - 0.00044 19.9 1.9 0.0016 18.1 1.3 1.9 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 ETS86749.1 - 0.0031 17.5 0.1 0.02 14.8 0.1 2.1 1 1 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 ETS86749.1 - 0.023 14.6 0.1 0.048 13.5 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 ETS86749.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UspB PF10625.4 ETS86749.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein B (UspB) RNA_pol_Rpb4 PF03874.11 ETS86750.1 - 2.2e-28 98.6 3.0 2.9e-28 98.2 2.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 MUG2_C PF08593.5 ETS86750.1 - 0.071 13.3 0.9 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal Sybindin PF04099.7 ETS86751.1 - 9.1e-52 174.5 0.0 1.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 ETS86751.1 - 4.2e-10 39.5 0.0 7.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 ETS86752.1 - 3.5e-14 53.2 0.1 4.3e-14 52.9 0.1 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 ETS86752.1 - 2.8e-08 33.5 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 ETS86752.1 - 1.2e-07 31.6 0.5 1.8e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 ETS86752.1 - 0.00014 21.1 1.3 0.0004 19.7 0.9 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF243 PF03103.12 ETS86752.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Nbl1_Borealin_N PF10444.4 ETS86753.1 - 1.1e-21 75.9 5.5 1.9e-21 75.1 3.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.17 ETS86754.1 - 3e-23 81.4 0.3 6e-23 80.4 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 ETS86754.1 - 0.014 15.2 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV NinG PF05766.7 ETS86754.1 - 0.1 12.3 2.6 0.16 11.7 1.8 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RhoGAP PF00620.22 ETS86755.1 - 2.6e-39 134.2 0.0 4.8e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 ETS86755.1 - 3.5e-30 103.8 44.4 1.3e-12 47.5 3.5 5.5 6 0 0 6 6 6 4 LIM domain SKG6 PF08693.5 ETS86756.1 - 0.0026 17.0 1.1 0.0051 16.0 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CPL PF08144.6 ETS86757.1 - 4.1e-18 65.6 0.0 3.5e-17 62.6 0.0 2.7 2 1 0 2 2 2 1 CPL (NUC119) domain TraH_2 PF06871.6 ETS86757.1 - 0.0076 15.7 0.2 0.0076 15.7 0.1 2.5 2 1 1 3 3 3 2 TraH_2 Ank_2 PF12796.2 ETS86757.1 - 0.082 13.2 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) RWD PF05773.17 ETS86758.1 - 1e-22 80.1 0.7 1.7e-22 79.4 0.5 1.4 1 0 0 1 1 1 1 RWD domain HrpE PF06188.7 ETS86758.1 - 0.17 11.5 3.2 0.26 11.0 2.2 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TPR_12 PF13424.1 ETS86759.1 - 3e-15 55.9 0.5 1.4e-06 28.1 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 ETS86759.1 - 3.4e-14 53.0 3.9 3.4e-06 27.5 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS86759.1 - 8.7e-12 44.0 2.1 0.00031 20.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS86759.1 - 5.6e-11 42.6 6.7 0.00014 22.1 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 ETS86759.1 - 1.4e-10 40.6 0.3 0.00088 18.8 0.0 4.2 3 1 2 5 5 5 2 TPR repeat TPR_14 PF13428.1 ETS86759.1 - 8.5e-07 29.0 8.4 0.38 11.5 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS86759.1 - 6.8e-06 25.5 0.1 0.00034 20.1 0.0 3.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS86759.1 - 3e-05 23.8 0.0 0.87 9.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS86759.1 - 4.2e-05 23.0 0.6 0.017 14.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 ETS86759.1 - 8.3e-05 22.3 4.8 2.4 8.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 ETS86759.1 - 0.00017 21.0 0.3 0.011 15.3 0.0 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 ETS86759.1 - 0.00018 21.6 0.0 0.24 11.5 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 ETS86759.1 - 0.0012 19.2 1.2 25 5.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 ETS86759.1 - 0.052 13.0 7.2 0.12 11.9 5.0 1.7 1 0 0 1 1 1 0 Nucleoplasmin TPR_20 PF14561.1 ETS86759.1 - 1.3 9.2 10.4 6.3 6.9 0.0 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat DNA_pol_phi PF04931.8 ETS86759.1 - 3.4 5.3 13.8 4.5 4.9 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TPR_4 PF07721.9 ETS86759.1 - 4.4 8.0 8.8 29 5.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0561 PF10573.4 ETS86761.1 - 1.7 8.5 5.9 0.5 10.2 0.2 2.6 1 1 2 3 3 3 0 Uncharacterised protein family UPF0561 Rad51 PF08423.6 ETS86762.1 - 5.1e-137 454.8 0.0 6.4e-137 454.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 ETS86762.1 - 2e-13 50.1 0.0 3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 ETS86762.1 - 4.9e-07 29.1 0.0 6.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 ETS86762.1 - 5.2e-07 29.7 0.5 1.6e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 ETS86762.1 - 1.2e-05 24.6 0.0 2.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 ETS86762.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 ETS86762.1 - 0.12 11.1 0.1 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 ETS86763.1 - 2.9e-126 421.8 0.0 3.9e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.10 ETS86764.1 - 9.7e-131 434.5 0.6 1.1e-130 434.3 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 ETS86764.1 - 0.00017 21.4 0.1 0.12 12.1 0.0 3.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 ETS86764.1 - 0.036 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Ribosomal_L6 PF00347.18 ETS86765.1 - 1.2e-27 96.1 4.9 6.6e-14 52.1 0.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Syndecan PF01034.15 ETS86766.1 - 0.43 10.2 1.3 1.1 8.9 0.9 1.6 1 0 0 1 1 1 0 Syndecan domain V-ATPase_H_N PF03224.9 ETS86767.1 - 3.8e-79 266.0 0.0 5e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 ETS86767.1 - 3e-37 127.1 0.0 7.8e-37 125.8 0.0 1.7 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 ETS86767.1 - 0.0041 17.3 1.5 0.085 13.1 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 ETS86767.1 - 0.0076 16.2 0.1 0.13 12.3 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 ETS86767.1 - 0.23 11.9 2.5 2.1 8.9 0.0 3.8 3 2 1 4 4 4 0 HEAT-like repeat RIX1 PF08167.7 ETS86767.1 - 0.3 10.7 2.8 18 4.9 0.0 4.0 3 2 2 5 5 5 0 rRNA processing/ribosome biogenesis Aldedh PF00171.17 ETS86768.1 - 4.6e-131 437.3 0.1 7.1e-131 436.7 0.1 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box PF00646.28 ETS86769.1 - 4.5e-06 26.1 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS86769.1 - 1.5e-05 24.6 0.6 3.2e-05 23.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like His_Phos_2 PF00328.17 ETS86770.1 - 3.8e-16 59.3 0.3 2.8e-12 46.6 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.1 ETS86770.1 - 0.0083 15.7 0.5 0.085 12.5 0.1 2.4 2 0 0 2 2 2 1 PDGLE domain Peptidase_C12 PF01088.16 ETS86772.1 - 1.7e-48 164.6 0.0 2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MFS_1 PF07690.11 ETS86773.1 - 2.1e-28 99.0 37.2 3.9e-28 98.1 25.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86773.1 - 4e-06 25.6 17.2 4e-06 25.6 11.9 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.6 ETS86774.1 - 1.4e-08 34.4 9.5 1.4e-08 34.4 6.6 2.0 2 0 0 2 2 2 1 CFEM domain Mucin PF01456.12 ETS86774.1 - 0.013 15.3 20.1 0.019 14.7 14.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF962 PF06127.6 ETS86777.1 - 3.8e-25 87.5 0.7 6.1e-25 86.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 ETS86778.1 - 8.4e-16 57.8 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 ETS86778.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain LAM_C PF12544.3 ETS86779.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 ETS86779.1 - 0.00084 19.5 0.2 0.0067 16.6 0.1 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 ETS86779.1 - 0.027 14.4 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1930 PF09122.5 ETS86779.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) BNR PF02012.15 ETS86782.1 - 3.4e-09 35.1 39.6 2.4 8.3 0.6 12.8 13 0 0 13 13 13 8 BNR/Asp-box repeat CP12 PF02672.10 ETS86782.1 - 0.017 15.5 0.3 0.055 13.9 0.2 1.8 1 0 0 1 1 1 0 CP12 domain WD40 PF00400.27 ETS86784.1 - 3.3e-23 80.6 17.6 2.2e-07 30.5 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 ETS86784.1 - 0.0059 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 ETS86784.1 - 0.033 13.6 0.2 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 ETS86784.1 - 0.17 10.1 0.0 0.29 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RRM_5 PF13893.1 ETS86785.1 - 4.4e-12 45.6 0.0 7.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS86785.1 - 1.9e-08 33.8 0.0 4.4e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS86785.1 - 3.3e-06 26.9 0.0 6.8e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 ETS86785.1 - 0.00037 20.1 0.2 0.0032 17.0 0.0 2.1 2 0 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 ETS86785.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 MSP1_C PF07462.6 ETS86785.1 - 2.6 6.3 5.2 3.2 6.0 3.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Autophagy_act_C PF03987.10 ETS86786.1 - 9.5e-15 54.5 0.0 1.9e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.15 ETS86787.1 - 1.9e-165 550.8 0.1 2.8e-165 550.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ost4 PF10215.4 ETS86787.1 - 3.2 7.3 4.9 6.1 6.4 3.4 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase AA_permease PF00324.16 ETS86788.1 - 7.7e-139 463.0 40.8 8.8e-139 462.9 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 ETS86788.1 - 1.3e-37 129.4 42.2 1.7e-37 128.9 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 ETS86788.1 - 0.15 10.4 0.1 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) LRR_6 PF13516.1 ETS86790.1 - 2e-12 45.8 3.7 0.02 14.9 0.0 6.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 ETS86790.1 - 1.2e-09 37.5 9.5 0.013 15.1 0.0 5.4 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS86790.1 - 1.9e-06 27.4 7.5 0.54 10.0 0.0 4.3 3 2 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 ETS86790.1 - 3.1e-06 26.4 3.7 5.1 7.5 0.0 6.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 ETS86790.1 - 0.00017 21.2 0.5 48 4.8 0.0 5.7 5 0 0 5 5 5 0 Leucine rich repeat SDA1 PF05285.7 ETS86790.1 - 0.94 8.6 17.2 1.2 8.2 11.9 1.2 1 0 0 1 1 1 0 SDA1 WBS_methylT PF12589.3 ETS86790.1 - 1.3 9.5 4.8 18 5.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Dynamin_M PF01031.15 ETS86791.1 - 9.5e-115 382.4 0.0 1.8e-114 381.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 ETS86791.1 - 3e-54 183.3 0.1 8.5e-54 181.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 ETS86791.1 - 1.3e-31 108.3 2.0 3.4e-31 106.9 1.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 ETS86791.1 - 0.0024 17.8 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 ETS86791.1 - 0.017 15.6 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 ETS86791.1 - 0.061 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 ETS86793.1 - 2.4e-13 49.4 0.8 0.16 11.8 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat UAA PF08449.6 ETS86794.1 - 2.8e-98 328.6 5.3 3.4e-98 328.3 3.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 ETS86794.1 - 7.1e-05 22.0 2.0 9.1e-05 21.6 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 ETS86794.1 - 0.0059 16.7 16.0 0.15 12.3 2.2 3.4 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 ETS86794.1 - 0.055 13.5 21.5 0.14 12.1 1.4 3.4 2 1 0 3 3 3 0 EamA-like transporter family TPT PF03151.11 ETS86794.1 - 1.6 8.3 15.2 0.099 12.2 5.7 2.5 1 1 1 2 2 2 0 Triose-phosphate Transporter family A_deaminase PF00962.17 ETS86795.1 - 1.3e-111 372.7 0.1 1.8e-111 372.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Prefoldin_2 PF01920.15 ETS86796.1 - 2.1e-16 59.6 5.5 2.5e-16 59.3 3.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit TMF_DNA_bd PF12329.3 ETS86796.1 - 0.017 14.8 1.8 0.017 14.8 1.2 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding LUC7 PF03194.10 ETS86796.1 - 0.033 13.7 3.5 0.04 13.4 2.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus FlxA PF14282.1 ETS86796.1 - 0.039 13.9 14.3 0.53 10.2 0.9 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF4455 PF14643.1 ETS86796.1 - 0.043 12.4 0.9 0.057 12.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Jnk-SapK_ap_N PF09744.4 ETS86796.1 - 0.051 13.5 0.7 0.051 13.5 0.5 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fzo_mitofusin PF04799.8 ETS86796.1 - 0.098 12.0 0.2 0.098 12.0 0.1 1.7 2 0 0 2 2 2 0 fzo-like conserved region TBPIP PF07106.8 ETS86796.1 - 0.14 11.7 6.5 0.44 10.0 0.2 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2681 PF10883.3 ETS86796.1 - 0.46 10.7 8.7 0.88 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3373 PF11853.3 ETS86796.1 - 2.4 6.5 5.6 0.39 9.2 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) GP41 PF00517.12 ETS86796.1 - 2.9 7.4 6.5 0.99 8.9 0.1 2.0 2 0 0 2 2 2 0 Retroviral envelope protein ADIP PF11559.3 ETS86796.1 - 5.3 6.9 14.0 1.4 8.8 1.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 ETS86796.1 - 5.5 7.1 8.1 0.99 9.5 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 ETS86796.1 - 5.7 6.6 8.0 1.6 8.4 1.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF16 PF01519.11 ETS86796.1 - 7.5 6.8 11.6 37 4.6 8.0 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Mito_carr PF00153.22 ETS86798.1 - 2.4e-56 187.4 2.5 6.5e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 ETS86799.1 - 2.7e-57 193.7 3.0 6.5e-45 153.0 2.1 2.2 2 0 0 2 2 2 2 Dor1-like family TRAM_LAG1_CLN8 PF03798.11 ETS86800.1 - 8.9e-48 162.4 15.3 8.9e-48 162.4 10.6 1.4 2 0 0 2 2 2 1 TLC domain DUF4611 PF15387.1 ETS86801.1 - 0.16 12.1 4.7 0.26 11.4 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cnd2 PF05786.9 ETS86801.1 - 0.33 9.4 3.1 0.4 9.1 2.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SH3_1 PF00018.23 ETS86802.1 - 4.1e-36 122.1 13.7 2.1e-13 49.4 0.1 4.6 5 0 0 5 5 5 3 SH3 domain SHD1 PF03983.7 ETS86802.1 - 4.2e-35 119.2 0.1 7.1e-35 118.4 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 ETS86802.1 - 4.2e-32 109.4 10.0 5.3e-12 45.1 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 ETS86802.1 - 6.3e-26 89.6 0.7 2.3e-09 36.5 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 ETS86802.1 - 7.8e-05 22.7 7.4 0.028 14.5 1.4 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 ETS86802.1 - 0.00013 21.9 39.4 0.00013 21.9 27.3 6.6 1 1 5 6 6 6 4 Domain of unknown function (DUF1720) Rpp20 PF12328.3 ETS86802.1 - 0.025 14.2 0.7 0.055 13.1 0.5 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Ceramidase PF05875.7 ETS86803.1 - 2.8e-87 292.2 7.4 3.2e-87 292.0 5.2 1.0 1 0 0 1 1 1 1 Ceramidase ABC2_membrane_5 PF13346.1 ETS86803.1 - 0.25 10.6 8.3 0.28 10.4 2.7 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein Virul_fac_BrkB PF03631.10 ETS86803.1 - 1.2 8.4 8.4 0.72 9.1 3.9 1.9 1 1 1 2 2 2 0 Virulence factor BrkB TMF_TATA_bd PF12325.3 ETS86804.1 - 8.5e-41 138.4 8.9 8.5e-41 138.4 6.2 6.4 3 2 4 7 7 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 ETS86804.1 - 4.1e-15 55.3 10.8 4.1e-15 55.3 7.5 9.7 4 3 6 11 11 11 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 ETS86804.1 - 0.0029 17.2 81.7 0.004 16.7 0.9 5.9 3 1 1 4 4 3 2 IncA protein HSBP1 PF06825.7 ETS86804.1 - 0.028 13.9 3.4 0.095 12.2 0.1 3.3 3 0 0 3 3 3 0 Heat shock factor binding protein 1 FlaC_arch PF05377.6 ETS86804.1 - 0.057 13.3 38.5 1.5 8.7 0.6 7.9 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 ETS86804.1 - 0.26 11.5 32.0 0.21 11.8 0.3 7.0 6 3 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 ETS86804.1 - 1 8.7 81.3 1.5 8.2 3.3 5.5 2 1 1 3 3 3 0 Intermediate filament protein GAS PF13851.1 ETS86804.1 - 1.5 7.9 76.4 0.16 11.1 9.0 5.6 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 ETS86804.1 - 1.6 7.3 70.5 0.86 8.1 11.9 4.9 2 1 1 4 4 4 0 Spc7 kinetochore protein DUF812 PF05667.6 ETS86804.1 - 5 5.5 72.9 0.36 9.2 1.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Phage_GP20 PF06810.6 ETS86804.1 - 9.4 5.6 75.9 0.018 14.4 2.9 6.5 3 2 3 6 6 6 0 Phage minor structural protein GP20 Ank_2 PF12796.2 ETS86805.1 - 6.5e-37 125.7 1.2 3.8e-12 46.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS86805.1 - 5.1e-36 121.8 1.5 1.5e-09 37.7 0.0 4.5 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 ETS86805.1 - 1.4e-33 113.0 0.5 5.4e-06 25.9 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 ETS86805.1 - 5.1e-33 112.8 2.7 8.7e-10 38.8 0.0 4.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86805.1 - 4e-27 91.5 0.0 0.0031 17.6 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.27 ETS86806.1 - 2.4e-55 182.5 10.0 1.8e-09 37.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 ETS86806.1 - 0.00085 17.5 4.2 2.8 5.9 0.1 4.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 ETS86806.1 - 0.078 13.2 0.0 6.4 7.2 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain AAA PF00004.24 ETS86807.1 - 1.5e-14 54.2 0.0 2.6e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS86807.1 - 1.4e-10 41.4 0.3 2.9e-09 37.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.13 ETS86807.1 - 1.7e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 ETS86807.1 - 1.9e-07 31.2 0.0 4.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS86807.1 - 0.00029 21.6 0.0 0.0036 18.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 ETS86807.1 - 0.0017 18.0 0.1 0.0056 16.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 ETS86807.1 - 0.0032 17.7 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 ETS86807.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 ETS86807.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 ETS86807.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 ETS86807.1 - 0.019 14.6 0.0 0.18 11.4 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 ETS86807.1 - 0.037 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 ETS86807.1 - 0.051 12.2 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 ETS86807.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RAM PF15320.1 ETS86808.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Prefoldin PF02996.12 ETS86809.1 - 2.1e-23 82.2 0.1 3.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Apolipoprotein PF01442.13 ETS86809.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CCDC155 PF14662.1 ETS86809.1 - 0.02 14.5 0.4 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Sec2p PF06428.6 ETS86809.1 - 0.023 14.5 2.9 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1041 PF06292.12 ETS86809.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) DUF1664 PF07889.7 ETS86809.1 - 0.092 12.5 1.3 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SSF PF00474.12 ETS86810.1 - 4.1e-19 68.4 28.0 5.6e-19 68.0 19.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family ABC2_membrane PF01061.19 ETS86811.1 - 2.3e-89 298.1 64.5 3.2e-48 163.6 13.7 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 ETS86811.1 - 1.3e-33 116.1 0.0 1.8e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS86811.1 - 1.3e-29 101.8 5.0 3.9e-24 84.2 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter DUF258 PF03193.11 ETS86811.1 - 5.2e-06 25.7 0.0 0.00034 19.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 ETS86811.1 - 1.8e-05 24.8 0.3 0.066 13.1 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS86811.1 - 6e-05 22.4 0.2 0.12 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain cobW PF02492.14 ETS86811.1 - 0.00012 21.6 0.3 0.00066 19.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 ETS86811.1 - 0.00013 21.3 0.0 0.032 13.6 0.0 3.2 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 ETS86811.1 - 0.00015 21.6 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 ETS86811.1 - 0.00018 21.6 0.1 0.056 13.5 0.0 3.2 3 1 1 4 4 2 1 AAA domain FtsK_SpoIIIE PF01580.13 ETS86811.1 - 0.00021 20.8 0.1 0.25 10.8 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_33 PF13671.1 ETS86811.1 - 0.00028 20.7 1.2 0.011 15.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 ETS86811.1 - 0.00037 20.5 0.2 0.0013 18.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 ETS86811.1 - 0.00062 19.7 0.6 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_trans_N PF14510.1 ETS86811.1 - 0.0007 19.6 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_17 PF13207.1 ETS86811.1 - 0.0011 19.8 0.0 0.027 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS86811.1 - 0.0024 18.1 0.0 0.031 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 ETS86811.1 - 0.0026 17.0 0.6 0.034 13.3 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 ETS86811.1 - 0.0031 17.1 1.0 0.84 9.1 0.2 2.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETS86811.1 - 0.0042 16.7 1.0 0.074 12.6 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 ETS86811.1 - 0.0086 16.5 0.0 0.31 11.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 ETS86811.1 - 0.0087 15.7 0.2 0.098 12.3 0.1 2.3 2 0 0 2 2 2 1 NACHT domain GBP PF02263.14 ETS86811.1 - 0.0093 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain NB-ARC PF00931.17 ETS86811.1 - 0.01 14.6 1.1 0.76 8.5 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.1 ETS86811.1 - 0.032 13.8 0.1 0.34 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETS86811.1 - 0.033 13.6 0.1 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 ETS86811.1 - 0.044 12.5 0.1 2.2 6.9 0.1 2.5 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 ETS86811.1 - 0.048 12.7 1.1 0.17 10.9 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 ETS86811.1 - 0.05 13.1 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 ETS86811.1 - 0.059 13.1 0.7 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 ETS86811.1 - 0.069 12.1 0.8 0.15 11.0 0.1 1.8 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.1 ETS86811.1 - 0.089 12.7 0.1 1.5 8.7 0.0 2.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 ETS86811.1 - 0.15 12.2 1.5 6.3 7.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 ETS86811.1 - 0.17 10.8 0.0 15 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 ETS86811.1 - 0.2 10.8 0.5 0.43 9.8 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Kinesin PF00225.18 ETS86812.1 - 6.1e-64 215.8 0.0 2.4e-63 213.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 ETS86812.1 - 0.047 13.8 0.0 0.047 13.8 0.0 2.5 3 1 0 3 3 3 0 AAA domain PspB PF06667.7 ETS86812.1 - 0.42 10.5 2.8 0.35 10.8 0.3 2.1 2 0 0 2 2 2 0 Phage shock protein B FAD_binding_3 PF01494.14 ETS86813.1 - 4.6e-28 98.2 0.1 3e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS86813.1 - 1.1e-10 40.9 4.3 8e-06 24.9 2.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS86813.1 - 9.1e-07 28.8 0.4 2.4e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 ETS86813.1 - 4.4e-06 27.0 0.1 0.00035 20.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS86813.1 - 2.4e-05 24.3 1.0 5.3e-05 23.1 0.7 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS86813.1 - 0.00014 20.4 0.1 0.00026 19.6 0.1 1.4 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 ETS86813.1 - 0.00026 19.9 2.4 0.0005 19.0 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 ETS86813.1 - 0.00034 19.6 0.6 0.00047 19.1 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS86813.1 - 0.00043 19.8 0.1 0.00097 18.7 0.0 1.5 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 ETS86813.1 - 0.00089 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 ETS86813.1 - 0.0025 17.4 0.7 0.0053 16.4 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 ETS86813.1 - 0.0039 17.2 0.1 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 ETS86813.1 - 0.0041 16.8 0.1 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Rossmann-like domain Thi4 PF01946.12 ETS86813.1 - 0.0058 15.7 0.1 0.014 14.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 ETS86813.1 - 0.0065 15.1 1.6 0.11 11.1 0.2 2.7 2 1 1 3 3 3 1 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 ETS86813.1 - 0.007 15.7 1.1 0.0098 15.2 0.3 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 ETS86813.1 - 0.019 13.8 0.6 0.098 11.5 0.4 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 ETS86813.1 - 0.033 13.9 0.2 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 ETS86813.1 - 0.06 13.1 0.5 0.25 11.0 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 ETS86813.1 - 0.12 11.3 0.8 0.24 10.4 0.6 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Glyco_transf_28 PF03033.15 ETS86814.1 - 3e-22 78.8 0.0 1.5e-21 76.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 ETS86814.1 - 2.3e-06 26.4 0.0 3.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 ETS86814.1 - 0.0037 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Peroxidase_2 PF01328.12 ETS86815.1 - 4.4e-34 117.5 0.1 5.7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EcKinase PF02958.15 ETS86816.1 - 2.3e-18 66.3 0.0 3.5e-10 39.5 0.0 2.6 2 1 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 ETS86816.1 - 1.2e-10 41.6 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS86816.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 ETS86816.1 - 0.054 12.1 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SR-25 PF10500.4 ETS86816.1 - 1.1 8.6 12.2 0.16 11.4 5.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 ETS86817.1 - 2.9e-46 157.7 40.1 2.9e-46 157.7 27.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86817.1 - 1.1e-11 43.9 22.8 8.4e-11 41.1 16.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS86817.1 - 0.0033 15.6 3.4 0.005 15.0 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 ETS86817.1 - 0.076 11.1 11.1 0.0061 14.7 4.4 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector Arylesterase PF01731.15 ETS86818.1 - 0.008 16.1 0.0 0.1 12.6 0.0 2.9 2 1 0 2 2 2 1 Arylesterase Peptidase_C48 PF02902.14 ETS86819.1 - 4.9e-19 68.8 0.1 7.9e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.1 ETS86820.1 - 1.6e-31 109.2 9.2 2.4e-31 108.6 6.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF2011 PF09428.5 ETS86820.1 - 0.16 11.8 5.7 0.29 11.0 4.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) IncA PF04156.9 ETS86820.1 - 0.83 9.2 5.9 1.7 8.1 3.7 1.5 1 1 0 1 1 1 0 IncA protein ThiF PF00899.16 ETS86821.1 - 1.7e-42 144.5 0.0 2.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 ETS86821.1 - 1e-24 85.9 0.1 1.8e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 ETS86821.1 - 5.6e-11 42.7 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 ETS86821.1 - 0.00029 20.9 0.4 0.011 15.7 0.3 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 ETS86821.1 - 0.077 13.2 0.0 0.31 11.3 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 ETS86821.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 ETS86821.1 - 0.39 9.7 1.7 0.6 9.1 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pam17 PF08566.5 ETS86822.1 - 7.6e-63 211.3 0.0 1e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.19 ETS86823.1 - 1.1e-11 44.2 1.1 5.9e-10 38.6 0.2 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FMN_dh PF01070.13 ETS86825.1 - 3.2e-108 361.7 0.0 4.4e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS86825.1 - 1.4e-21 76.0 0.0 2.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS86825.1 - 1.6e-05 24.0 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS86825.1 - 0.00017 20.5 0.2 0.0041 16.0 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 ETS86825.1 - 0.0039 16.2 0.0 0.61 9.1 0.0 2.8 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 ETS86825.1 - 0.02 14.0 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Glyco_hydro_16 PF00722.16 ETS86826.1 - 6.7e-13 48.3 0.6 1.2e-12 47.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 ETS86826.1 - 0.031 14.1 0.8 0.36 10.6 0.5 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Laminin_G_3 PF13385.1 ETS86826.1 - 0.45 10.7 10.9 0.056 13.6 4.1 2.0 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Dynamin_N PF00350.18 ETS86827.1 - 3.8e-16 59.3 2.4 1.8e-15 57.1 0.0 3.0 2 2 0 2 2 1 1 Dynamin family MMR_HSR1 PF01926.18 ETS86827.1 - 2.9e-06 27.2 0.0 3.3e-05 23.8 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 ETS86827.1 - 0.00033 19.8 0.0 0.006 15.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 ETS86827.1 - 0.0022 16.8 0.1 0.0068 15.2 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 ETS86827.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 3.0 2 1 0 2 2 1 1 ABC transporter Miro PF08477.8 ETS86827.1 - 0.0067 16.9 0.1 0.036 14.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 ETS86827.1 - 0.01 16.0 0.1 1.8 8.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 ETS86827.1 - 0.01 16.6 1.5 0.071 13.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 ETS86827.1 - 0.021 14.8 0.6 0.32 10.9 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 ETS86827.1 - 0.095 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 ETS86827.1 - 0.34 10.8 3.3 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4011 PF13195.1 ETS86827.1 - 6.1 6.8 15.1 12 5.8 8.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4011) DUF2427 PF10348.4 ETS86828.1 - 3 7.4 10.5 1.6 8.3 4.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2306 PF10067.4 ETS86828.1 - 4.8 7.3 11.6 0.07 13.2 1.4 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Thioredoxin_7 PF13899.1 ETS86829.1 - 3.3e-12 46.2 0.0 8.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 ETS86829.1 - 2e-11 43.2 0.1 7e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 ETS86829.1 - 8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 ETS86829.1 - 2e-05 24.4 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 ETS86829.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain UIM PF02809.15 ETS86829.1 - 3 7.6 7.0 1.6 8.5 1.1 3.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Ecm29 PF13001.2 ETS86830.1 - 3.4e-100 335.9 0.5 6.4e-100 335.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 ETS86830.1 - 3e-08 33.0 3.6 1.9 8.7 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 ETS86830.1 - 3.3e-05 24.2 10.0 0.44 11.0 0.0 8.8 10 0 0 10 10 10 2 HEAT-like repeat RRM_1 PF00076.17 ETS86831.1 - 1.6e-46 155.7 0.0 1.6e-16 59.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS86831.1 - 4e-27 93.9 0.0 6.5e-10 38.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS86831.1 - 1.3e-23 82.6 0.0 1.4e-08 34.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 ETS86831.1 - 8.5e-07 28.7 0.0 0.00016 21.5 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 ETS86831.1 - 4.7e-05 23.0 0.0 0.0036 17.0 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 ETS86832.1 - 1.4e-69 234.1 0.0 2.1e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86832.1 - 4.3e-50 170.2 0.0 6.9e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS86832.1 - 0.0074 15.2 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Vps23_core PF09454.5 ETS86832.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Vps23 core domain Methyltransf_23 PF13489.1 ETS86833.1 - 2.7e-20 72.7 0.1 4.4e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86833.1 - 2.7e-11 43.2 0.0 1.8e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86833.1 - 4.2e-10 39.9 0.0 9.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86833.1 - 2.7e-09 37.6 0.0 3.9e-08 33.8 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86833.1 - 2.2e-07 31.2 0.0 8.5e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 ETS86833.1 - 0.0038 17.2 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 ETS86833.1 - 0.0041 16.1 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 ETS86833.1 - 0.007 15.5 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 ETS86833.1 - 0.011 16.1 0.0 0.063 13.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain GidB PF02527.10 ETS86833.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.4 ETS86833.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 ETS86833.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 ETS86833.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS86833.1 - 0.052 12.6 0.0 0.23 10.5 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 ETS86833.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Esterase_phd PF10503.4 ETS86834.1 - 8.9e-24 83.9 0.2 1.2e-23 83.5 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 ETS86834.1 - 1.6e-08 34.0 1.6 2.7e-08 33.2 1.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS86834.1 - 2.3e-08 33.9 0.3 3.4e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS86834.1 - 0.0032 17.3 0.8 0.0057 16.5 0.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 ETS86834.1 - 0.078 12.5 0.1 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.17 ETS86835.1 - 3e-15 56.8 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS86835.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain BolA PF01722.13 ETS86835.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein Sugar_tr PF00083.19 ETS86836.1 - 1.6e-78 264.3 24.2 1.9e-78 264.1 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86836.1 - 1.4e-16 60.1 34.4 1.4e-16 60.1 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.15 ETS86836.1 - 0.00014 20.6 1.7 0.00014 20.6 1.2 2.1 2 0 0 2 2 2 1 Phosphate transporter family Fungal_trans PF04082.13 ETS86837.1 - 2.7e-19 69.0 0.1 3.5e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86837.1 - 0.57 10.1 14.3 5.1 7.0 9.9 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.13 ETS86838.1 - 1.3e-34 119.5 0.0 2.5e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 ETS86838.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 TPR_19 PF14559.1 ETS86840.1 - 8.3e-05 22.8 0.7 0.13 12.5 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS86840.1 - 0.012 15.7 0.0 0.057 13.5 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 ETS86840.1 - 0.013 15.1 2.2 0.044 13.4 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 ETS86840.1 - 0.15 12.0 3.6 88 3.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 ETS86840.1 - 0.47 11.2 6.5 15 6.5 0.6 4.6 4 2 2 6 6 6 0 Tetratricopeptide repeat Adaptin_N PF01602.15 ETS86841.1 - 1e-94 317.7 6.5 1.8e-94 317.0 4.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 ETS86841.1 - 2.4e-63 211.6 0.0 7.8e-63 209.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 ETS86841.1 - 8.2e-63 210.2 0.3 1.7e-62 209.2 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 ETS86841.1 - 4.2e-12 46.1 5.7 1.9e-07 31.2 0.0 4.7 1 1 2 3 3 3 3 HEAT repeats Cnd1 PF12717.2 ETS86841.1 - 7.8e-05 22.5 7.5 0.0039 17.0 0.0 3.7 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 ETS86841.1 - 0.00082 19.2 0.2 1.3 9.2 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 ETS86841.1 - 0.0049 17.3 3.0 1.2 9.7 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat RE_Alw26IDE PF09665.5 ETS86841.1 - 0.047 12.3 1.6 0.4 9.3 0.3 2.5 2 1 0 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 ETS86842.1 - 4.5e-73 243.6 0.2 5.2e-73 243.4 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 ETS86843.1 - 3.1e-68 228.7 0.2 4.3e-68 228.2 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.13 ETS86844.1 - 2.5e-10 40.2 0.0 4.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 ETS86844.1 - 1.9e-08 34.3 0.0 9.7e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 ETS86844.1 - 0.032 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2779 PF11074.3 ETS86844.1 - 0.071 13.1 0.1 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Ribonuc_P_40 PF08584.6 ETS86845.1 - 3e-64 216.7 0.0 4.5e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.1 ETS86846.1 - 5.7e-11 42.3 0.4 5.5e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS86846.1 - 5.4e-10 39.5 0.0 3e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS86846.1 - 6e-05 23.3 0.1 0.00013 22.2 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86846.1 - 0.00044 19.9 0.1 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 ETS86846.1 - 0.001 19.0 0.1 0.005 16.9 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeat DnaG_DnaB_bind PF08278.6 ETS86846.1 - 0.079 13.1 1.6 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding VP9 PF09625.5 ETS86846.1 - 0.19 11.5 0.4 0.52 10.1 0.0 1.9 2 1 1 3 3 3 0 VP9 protein Glycos_transf_3 PF00591.16 ETS86847.1 - 3.3e-64 216.7 0.0 5.4e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 ETS86847.1 - 7.3e-11 41.5 0.0 2e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain RNA_lig_T4_1 PF09511.5 ETS86848.1 - 4.8e-79 264.9 0.0 8e-79 264.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 ETS86848.1 - 4.7e-73 245.5 0.1 6.5e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 ETS86848.1 - 1.3e-56 191.0 0.2 2.4e-56 190.1 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 ETS86848.1 - 0.0035 17.2 0.8 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain PK PF00224.16 ETS86848.1 - 0.03 12.9 0.0 0.049 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ABC_tran PF00005.22 ETS86848.1 - 0.076 13.3 0.7 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Ribosomal_L10 PF00466.15 ETS86849.1 - 0.00059 19.7 0.0 0.0068 16.3 0.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L10 Tic20 PF09685.5 ETS86850.1 - 1.6e-07 31.2 1.1 2.2e-07 30.8 0.8 1.1 1 0 0 1 1 1 1 Tic20-like protein Imm_superinfect PF14373.1 ETS86850.1 - 0.34 10.5 4.4 0.61 9.7 3.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein Rad60-SLD PF11976.3 ETS86851.1 - 6.8e-06 25.6 0.0 1.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 ETS86851.1 - 0.0001 22.3 0.4 0.00027 21.0 0.3 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 ETS86851.1 - 0.00021 20.6 0.0 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Bin3 PF06859.7 ETS86853.1 - 8.6e-28 96.5 0.0 1.3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 ETS86853.1 - 8.8e-12 45.6 0.0 1.3e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86853.1 - 1.2e-11 44.6 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86853.1 - 4.5e-09 36.0 0.0 5.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86853.1 - 1.5e-08 35.0 0.0 2.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86853.1 - 1.1e-06 28.7 0.1 2.6e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86853.1 - 3e-06 27.6 0.0 5.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS86853.1 - 3.3e-05 23.3 0.0 6.9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 ETS86853.1 - 5.2e-05 23.5 0.0 8.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 ETS86853.1 - 0.0066 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 ETS86853.1 - 0.017 13.8 0.1 0.033 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.8 ETS86853.1 - 0.035 13.2 0.0 0.085 11.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 ETS86853.1 - 0.053 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) SET PF00856.23 ETS86854.1 - 9.7e-21 74.7 0.3 1.4e-19 71.0 0.0 2.6 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 ETS86854.1 - 1.1e-20 73.7 5.1 2.4e-20 72.7 2.1 2.2 2 0 0 2 2 2 1 Pre-SET motif Metallothio_2 PF01439.13 ETS86854.1 - 6.7 7.3 17.9 3 8.4 8.7 2.7 2 1 1 3 3 3 0 Metallothionein ADH_N PF08240.7 ETS86856.1 - 5.2e-07 29.4 0.0 2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS86856.1 - 2.7e-06 26.9 0.3 0.0011 18.4 0.0 2.5 3 0 0 3 3 3 2 Zinc-binding dehydrogenase SurE PF01975.12 ETS86858.1 - 3.1e-39 134.3 0.1 4.1e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE Kinesin PF00225.18 ETS86859.1 - 6.3e-58 196.0 0.0 1.3e-57 195.0 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain RIX1 PF08167.7 ETS86859.1 - 0.12 12.0 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis PKI PF02827.11 ETS86859.1 - 0.52 10.4 5.0 0.43 10.7 0.2 3.1 3 0 0 3 3 3 0 cAMP-dependent protein kinase inhibitor Jnk-SapK_ap_N PF09744.4 ETS86859.1 - 2.9 7.8 12.1 0.15 12.0 3.7 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Bac_rhamnosid PF05592.6 ETS86861.1 - 3e-161 537.1 0.0 4e-161 536.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 ETS86861.1 - 1.2e-52 177.8 0.3 2.4e-52 176.9 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.13 ETS86861.1 - 0.0095 15.5 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_31 PF01055.21 ETS86862.1 - 5.8e-124 414.2 0.4 7e-124 414.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 ETS86862.1 - 8.4e-05 22.3 2.1 0.00035 20.3 0.0 2.9 3 1 0 3 3 3 1 Galactose mutarotase-like ADH_N PF08240.7 ETS86863.1 - 1e-05 25.2 0.0 2.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS86863.1 - 6.2e-05 22.5 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 ETS86863.1 - 0.00023 22.0 0.0 0.0011 19.8 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF4054 PF13262.1 ETS86863.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) RTA1 PF04479.8 ETS86864.1 - 1.9e-45 155.1 2.8 2.4e-45 154.8 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 ETS86864.1 - 0.029 13.6 0.1 0.055 12.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Nop52 PF05997.7 ETS86865.1 - 2.1e-46 158.1 0.1 2.6e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 PBP1_TM PF14812.1 ETS86865.1 - 2.1 8.6 10.7 1.8 8.8 4.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DAGK_cat PF00781.19 ETS86866.1 - 1.6e-24 85.8 0.0 1.3e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain POC1 PF10450.4 ETS86866.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 POC1 chaperone zf-CHY PF05495.7 ETS86867.1 - 8.8e-14 51.4 11.9 1.3e-13 50.8 8.2 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-rbx1 PF12678.2 ETS86867.1 - 0.18 11.9 9.1 0.36 10.9 6.3 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zinc_ribbon_5 PF13719.1 ETS86867.1 - 0.56 9.8 8.2 2.7 7.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 ETS86867.1 - 0.81 9.4 8.8 3.8 7.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 ETS86867.1 - 3.9 7.3 13.0 1e+02 2.8 9.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon Ish1 PF10281.4 ETS86868.1 - 1.6e-78 258.3 30.3 7.1e-13 48.3 0.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 ETS86868.1 - 4.4e-11 42.0 0.0 0.27 10.7 0.0 8.3 10 0 0 10 10 10 2 SAP domain HeH PF12949.2 ETS86868.1 - 1.9e-07 30.4 0.0 5.7 6.5 0.0 6.3 6 0 0 6 6 6 3 HeH/LEM domain Slx4 PF09494.5 ETS86868.1 - 1.4e-06 27.9 2.6 6.7 6.5 0.0 6.6 7 0 0 7 7 7 1 Slx4 endonuclease APC2 PF08672.6 ETS86868.1 - 0.00055 20.1 4.6 17 5.7 0.0 6.2 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 DUF3612 PF12268.3 ETS86868.1 - 0.0085 15.8 0.3 22 4.7 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3612) Thioredoxin_6 PF13848.1 ETS86868.1 - 0.12 12.1 0.0 9.7 5.9 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like domain TrbI PF03743.9 ETS86868.1 - 2.2 7.7 5.2 0.31 10.5 0.2 2.0 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein Aa_trans PF01490.13 ETS86870.1 - 1.8e-28 99.1 20.9 3.1e-28 98.4 14.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF604 PF04646.7 ETS86871.1 - 1.5e-07 30.9 0.1 8.3e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 ETS86871.1 - 1.1e-05 24.7 0.0 2.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Glyco_transf_25 PF01755.12 ETS86872.1 - 7.6e-06 25.7 0.0 0.00081 19.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Herpes_gE PF02480.11 ETS86873.1 - 0.0003 19.2 0.5 0.0009 17.6 0.3 1.6 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 ETS86873.1 - 0.0071 16.5 0.4 0.0071 16.5 0.3 2.3 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 ETS86873.1 - 0.08 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) gpUL132 PF11359.3 ETS86873.1 - 0.13 11.6 8.3 0.19 11.0 5.8 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Mucin PF01456.12 ETS86873.1 - 0.13 11.9 27.4 0.04 13.6 17.1 1.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Pol_alpha_B_N PF08418.5 ETS86873.1 - 0.21 11.0 6.7 0.33 10.4 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal VSP PF03302.8 ETS86873.1 - 0.47 9.0 11.2 0.91 8.0 7.8 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein Macoilin PF09726.4 ETS86873.1 - 1.7 6.8 6.1 2.1 6.5 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M13 PF01431.16 ETS86874.1 - 1.5e-37 128.7 2.4 9.9e-37 126.1 1.7 2.2 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 ETS86874.1 - 1.3e-28 100.1 0.2 5.9e-28 97.9 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M13 Mannosyl_trans3 PF11051.3 ETS86875.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative SPA PF08616.5 ETS86876.1 - 0.13 11.9 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Stabilization of polarity axis DUF913 PF06025.7 ETS86876.1 - 5.3 5.6 6.6 2 7.0 2.7 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) ORC6 PF05460.8 ETS86876.1 - 6.4 5.7 11.1 10 5.1 7.4 1.7 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF1857 PF08982.6 ETS86877.1 - 8.2e-40 135.8 0.0 9.2e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Aldo_ket_red PF00248.16 ETS86878.1 - 9.2e-40 136.2 0.0 1.4e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 ETS86880.1 - 3.4e-24 85.3 0.0 9.9e-23 80.6 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86880.1 - 1.1e-05 24.6 0.0 0.081 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETS86880.1 - 0.012 15.3 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hydrophobin_2 PF06766.6 ETS86881.1 - 2.8e-23 81.3 11.1 3.6e-23 81.0 7.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin zf-C3Hc3H PF13891.1 ETS86881.1 - 7 6.7 6.9 12 6.0 1.1 2.3 1 1 0 2 2 2 0 Potential DNA-binding domain NARP1 PF12569.3 ETS86882.1 - 5e-198 659.0 30.9 1.7e-197 657.3 13.6 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 ETS86882.1 - 5.1e-25 87.5 33.6 2.6e-05 24.7 0.0 8.8 7 2 1 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 ETS86882.1 - 5.9e-23 80.3 36.2 1.9e-06 27.3 0.1 7.9 5 1 2 8 8 8 6 TPR repeat TPR_19 PF14559.1 ETS86882.1 - 2.9e-21 75.5 38.3 0.00013 22.2 0.1 8.1 7 2 2 9 9 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 ETS86882.1 - 1.2e-20 72.0 26.0 0.00031 21.0 0.0 11.1 7 3 5 12 12 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 ETS86882.1 - 1.4e-16 58.9 49.6 2e-06 27.2 0.1 12.4 12 2 0 12 12 11 5 Tetratricopeptide repeat TPR_9 PF13371.1 ETS86882.1 - 2.1e-16 59.5 8.1 3.2e-05 23.7 0.2 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 ETS86882.1 - 2.5e-15 55.3 30.5 1.2e-06 27.9 0.1 9.9 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 ETS86882.1 - 9.7e-12 44.6 37.6 0.00089 19.1 0.0 7.6 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 ETS86882.1 - 1.7e-11 43.3 22.5 0.034 14.3 0.0 9.9 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 ETS86882.1 - 1.1e-09 37.7 21.1 0.0023 17.0 3.3 5.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS86882.1 - 8.6e-09 34.5 26.4 3.4e-05 23.3 0.0 9.6 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 ETS86882.1 - 1.3e-07 30.8 18.4 0.0098 15.6 0.0 8.2 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 ETS86882.1 - 0.00012 22.1 1.0 0.65 10.5 0.3 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 ETS86882.1 - 0.031 14.7 43.6 0.13 12.7 0.1 10.8 13 0 0 13 13 11 0 Tetratricopeptide repeat TPR_10 PF13374.1 ETS86882.1 - 0.23 11.4 19.5 22 5.1 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 ETS86882.1 - 0.45 10.7 18.4 0.78 9.9 0.4 4.8 5 0 0 5 5 5 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.1 ETS86882.1 - 2.1 8.2 20.8 7.6 6.5 0.1 6.1 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.4 ETS86883.1 - 2.6e-48 163.9 0.4 3.1e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AAA PF00004.24 ETS86884.1 - 9.1e-40 135.9 0.0 1.8e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS86884.1 - 0.00014 21.6 1.5 0.0008 19.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS86884.1 - 0.00015 21.7 0.5 0.013 15.5 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 ETS86884.1 - 0.0003 19.9 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 ETS86884.1 - 0.0014 18.5 0.3 0.0091 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 ETS86884.1 - 0.003 17.6 3.3 0.019 15.1 0.0 2.9 3 1 1 4 4 3 1 AAA domain PhoH PF02562.11 ETS86884.1 - 0.0046 16.2 0.3 0.045 12.9 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 ETS86884.1 - 0.0067 15.6 0.1 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 ETS86884.1 - 0.0085 15.0 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 ETS86884.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS86884.1 - 0.018 14.7 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 ETS86884.1 - 0.023 14.1 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 ETS86884.1 - 0.038 13.3 1.5 0.35 10.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 ETS86884.1 - 0.045 14.5 2.2 0.087 13.6 0.1 2.5 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 ETS86884.1 - 0.049 13.2 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF2115 PF09888.4 ETS86884.1 - 0.12 12.4 0.7 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) AAA_11 PF13086.1 ETS86884.1 - 0.43 10.1 2.7 0.85 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain Cyclin PF08613.6 ETS86885.1 - 5.7e-12 46.2 0.0 9.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 ETS86885.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain APC_CDC26 PF10471.4 ETS86885.1 - 0.11 13.2 0.2 11 6.8 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PHD PF00628.24 ETS86886.1 - 1.7e-07 30.8 9.2 2.8e-07 30.1 6.4 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 ETS86886.1 - 0.0021 17.7 5.1 0.0021 17.7 3.5 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 ETS86886.1 - 0.011 15.0 10.7 0.069 12.4 7.4 2.2 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 ETS86886.1 - 0.08 12.8 4.3 0.14 12.0 3.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 ETS86886.1 - 0.13 12.0 4.3 0.29 10.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AT_hook PF02178.14 ETS86886.1 - 0.67 9.8 15.4 0.37 10.6 4.2 3.4 2 0 0 2 2 2 0 AT hook motif zf-PHD-like PF15446.1 ETS86886.1 - 1.9 7.7 11.5 0.32 10.2 4.0 2.3 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_hydro_17 PF00332.13 ETS86887.1 - 0.0012 17.9 0.8 0.0064 15.5 0.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 ETS86887.1 - 0.0027 16.5 0.1 0.0042 15.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Isochorismatase PF00857.15 ETS86888.1 - 6.3e-25 88.0 0.0 7.3e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Sulfatase PF00884.18 ETS86889.1 - 4.1e-56 190.4 1.3 5.6e-56 189.9 0.9 1.2 1 0 0 1 1 1 1 Sulfatase Aminotran_3 PF00202.16 ETS86890.1 - 4.4e-47 160.5 0.3 4.3e-46 157.3 0.2 2.0 1 1 0 1 1 1 1 Aminotransferase class-III EutQ PF06249.7 ETS86890.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ YtfJ_HI0045 PF09695.5 ETS86890.1 - 0.065 12.5 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) adh_short PF00106.20 ETS86891.1 - 1.5e-15 57.4 1.1 2.6e-15 56.7 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS86891.1 - 1.4e-07 31.3 0.4 2.1e-07 30.7 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS86891.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CRC_subunit PF08624.5 ETS86892.1 - 4.5e-56 188.6 0.0 6.4e-56 188.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Glyco_hydro_18 PF00704.23 ETS86893.1 - 7.9e-22 78.1 1.3 7.9e-22 78.1 0.9 2.7 2 1 0 3 3 3 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 ETS86893.1 - 1.4e-09 37.3 12.4 1.4e-09 37.3 8.6 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain TauD PF02668.11 ETS86894.1 - 8.8e-25 87.8 0.3 1.1e-24 87.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cys_rich_CPCC PF14206.1 ETS86894.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC DUF2749 PF10907.3 ETS86895.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Arylsulfotran_2 PF14269.1 ETS86896.1 - 2.7e-98 328.8 2.6 3.6e-98 328.4 1.8 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RHS PF03527.9 ETS86896.1 - 0.03 14.0 1.0 1.5 8.6 0.0 3.3 3 0 0 3 3 3 0 RHS protein DUF2088 PF09861.4 ETS86898.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) Cyclase PF04199.8 ETS86899.1 - 5.9e-33 113.9 0.2 7.3e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase HET PF06985.6 ETS86900.1 - 1.4e-22 80.3 0.2 2.9e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS86903.1 - 3.5e-37 127.6 0.1 9.5e-37 126.2 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 ETS86904.1 - 5.4e-60 203.2 0.0 7.2e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PQQ_3 PF13570.1 ETS86905.1 - 0.0072 16.5 1.1 1.8 8.9 0.0 4.3 5 2 1 6 6 6 1 PQQ-like domain DUF4394 PF14339.1 ETS86905.1 - 0.029 13.6 0.0 4.2 6.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4394) PQQ PF01011.16 ETS86905.1 - 0.13 11.8 0.1 30 4.3 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat FAD_binding_3 PF01494.14 ETS86906.1 - 1.2e-25 90.3 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS86906.1 - 1.6e-07 30.5 0.0 0.00044 19.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS86906.1 - 7.1e-07 29.5 0.1 0.00037 20.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 ETS86906.1 - 7.3e-05 21.5 0.8 1.1 7.8 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 ETS86906.1 - 0.00018 21.4 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS86906.1 - 0.00037 19.4 0.3 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 ETS86906.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 ETS86906.1 - 0.009 15.9 0.1 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 ETS86906.1 - 0.018 13.8 0.0 0.041 12.6 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 ETS86906.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS86906.1 - 0.034 13.7 0.1 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETS86906.1 - 0.052 12.6 0.2 0.15 11.0 0.0 1.8 2 1 1 3 3 3 0 Thi4 family 3HCDH_N PF02737.13 ETS86906.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 ETS86906.1 - 0.083 11.9 0.5 0.24 10.4 0.1 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Tyrosinase PF00264.15 ETS86907.1 - 2.5e-47 161.9 0.0 3.5e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.17 ETS86908.1 - 1.6e-71 241.2 0.0 1.9e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF637 PF04830.8 ETS86908.1 - 0.26 10.9 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) Acetyltransf_1 PF00583.19 ETS86910.1 - 1.9e-06 27.8 0.1 4.4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS86910.1 - 8.5e-05 22.6 0.0 0.00025 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 ETS86910.1 - 0.00043 20.1 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS86910.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 ETS86911.1 - 2.5e-30 104.6 7.4 1.7e-10 41.0 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86911.1 - 5.1e-20 70.2 2.3 0.055 13.2 0.0 8.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 ETS86911.1 - 1.1e-14 53.0 0.3 2 8.9 0.0 8.9 9 0 0 9 9 8 3 Ankyrin repeat Ank_4 PF13637.1 ETS86911.1 - 4.7e-12 46.0 1.8 0.018 15.5 0.0 6.4 3 3 4 7 7 7 3 Ankyrin repeats (many copies) NACHT PF05729.7 ETS86911.1 - 5.9e-12 45.5 0.2 1.7e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.1 ETS86911.1 - 4.1e-08 33.2 3.4 1.2 9.4 0.0 6.7 3 2 4 7 7 7 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 ETS86911.1 - 1.1e-06 28.7 0.1 6.9e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS86911.1 - 0.00052 20.1 0.6 0.0025 17.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 ETS86911.1 - 0.0011 18.0 0.2 0.2 10.6 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain Syntaxin PF00804.20 ETS86911.1 - 0.011 15.8 1.0 0.049 13.7 0.7 2.1 1 0 0 1 1 1 0 Syntaxin AFG1_ATPase PF03969.11 ETS86911.1 - 0.025 13.4 0.0 0.047 12.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Shigella_OspC PF06128.6 ETS86911.1 - 0.029 13.8 0.2 0.17 11.3 0.0 2.3 2 1 0 2 2 2 0 Shigella flexneri OspC protein PALP PF00291.20 ETS86911.1 - 0.049 12.8 2.1 0.33 10.1 0.3 2.4 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme AAA_14 PF13173.1 ETS86911.1 - 0.06 13.2 0.0 0.29 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 ETS86913.1 - 2.2e-25 88.7 0.9 2.9e-25 88.3 0.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS86913.1 - 1.2e-18 67.1 1.4 1.7e-18 66.7 0.9 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 ETS86913.1 - 0.0005 19.8 1.0 0.0006 19.5 0.1 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 ETS86913.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 ETS86913.1 - 0.12 12.6 1.4 0.2 11.9 0.2 1.9 1 1 1 2 2 2 0 Cold shock protein DEAD box A CENP-H PF05837.7 ETS86914.1 - 1.3e-27 95.9 12.8 2e-26 92.2 4.9 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) IncA PF04156.9 ETS86914.1 - 0.095 12.2 8.9 0.021 14.4 1.1 2.1 2 0 0 2 2 2 0 IncA protein DUF1192 PF06698.6 ETS86914.1 - 0.19 11.5 4.7 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) AATF-Che1 PF13339.1 ETS86914.1 - 0.57 10.3 7.5 1.8 8.7 1.0 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TMF_TATA_bd PF12325.3 ETS86914.1 - 7.2 6.3 12.6 0.42 10.3 4.2 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 ETS86914.1 - 9.4 5.8 15.4 0.72 9.3 0.3 3.3 2 2 0 3 3 3 0 Septum formation initiator Bap31 PF05529.7 ETS86914.1 - 9.6 5.6 7.2 1.5 8.2 2.3 1.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like ATG11 PF10377.4 ETS86915.1 - 1.3e-37 128.5 0.1 1.3e-37 128.5 0.1 3.3 3 0 0 3 3 3 1 Autophagy-related protein 11 AAA_13 PF13166.1 ETS86915.1 - 1.2 7.4 48.2 0.14 10.6 14.9 3.8 3 1 1 4 4 4 0 AAA domain DUF869 PF05911.6 ETS86915.1 - 3.9 5.5 64.9 0.0065 14.7 15.1 3.6 1 1 3 4 4 4 0 Plant protein of unknown function (DUF869) Ribosomal_L9_N PF01281.14 ETS86916.1 - 5.9e-09 35.0 0.0 1.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 ETS86916.1 - 0.016 15.2 0.3 0.85 9.7 0.2 2.6 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain ABC_tran PF00005.22 ETS86917.1 - 2e-33 115.6 0.0 5.1e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 ETS86917.1 - 2e-19 70.0 12.0 2e-19 70.0 8.3 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 ETS86917.1 - 5.7e-08 32.2 2.8 3.2e-05 23.2 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS86917.1 - 9.3e-07 29.0 0.1 0.00092 19.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETS86917.1 - 0.00042 19.7 0.1 0.0011 18.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 ETS86917.1 - 0.0029 17.1 0.0 0.0077 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 ETS86917.1 - 0.0033 17.5 0.4 0.021 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS86917.1 - 0.019 14.9 0.2 0.073 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 ETS86917.1 - 0.029 13.8 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 ETS86917.1 - 0.038 13.9 0.4 0.64 9.9 0.3 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 ETS86917.1 - 0.046 12.9 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 ETS86917.1 - 0.053 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETS86917.1 - 0.12 12.1 0.5 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Chitin_bind_1 PF00187.14 ETS86918.1 - 0.00021 21.1 18.0 0.00036 20.4 12.5 1.4 1 0 0 1 1 1 1 Chitin recognition protein NADH_Oxid_Nqo15 PF11497.3 ETS86918.1 - 1.2 8.8 3.6 5.4 6.7 0.0 3.6 3 0 0 3 3 3 0 NADH-quinone oxidoreductase chain 15 ECH PF00378.15 ETS86919.1 - 1.3e-18 67.0 0.0 1.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 ETS86919.1 - 0.035 13.8 0.0 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 PGM_PMM_I PF02878.11 ETS86920.1 - 3.8e-34 117.1 0.0 5.7e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 ETS86920.1 - 2.9e-25 88.5 0.0 6e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 ETS86920.1 - 8.8e-15 54.9 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 ETS86920.1 - 3.1e-09 36.6 0.0 7.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 ETS86921.1 - 9.6e-29 100.7 0.2 1.1e-28 100.5 0.1 1.0 1 0 0 1 1 1 1 Exonuclease Tim54 PF11711.3 ETS86923.1 - 2.2e-119 398.5 4.2 4.5e-119 397.4 2.9 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Glyco_hydro_3 PF00933.16 ETS86924.1 - 2.2e-85 286.2 0.0 3e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS86924.1 - 1.2e-41 142.7 0.0 1.5e-40 139.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS86924.1 - 1.8e-22 79.0 0.3 7.5e-22 77.0 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain p450 PF00067.17 ETS86925.1 - 5.7e-38 130.6 0.0 7.3e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M56 PF05569.6 ETS86926.1 - 1.4 7.8 8.8 0.21 10.5 0.8 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 FAD-oxidase_C PF02913.14 ETS86927.1 - 9.5e-29 100.4 0.0 1.6e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 ETS86927.1 - 2.9e-28 98.0 0.0 5.2e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HET PF06985.6 ETS86928.1 - 1.7e-28 99.5 3.0 2.8e-28 98.8 2.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COPI_C PF06957.6 ETS86928.1 - 0.063 11.8 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus GST_N_3 PF13417.1 ETS86930.1 - 1.5e-10 41.1 0.1 1.7e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS86930.1 - 4.8e-08 32.8 0.0 1.4e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS86930.1 - 0.0081 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyr_redox_3 PF13738.1 ETS86931.1 - 3.8e-21 76.0 0.0 5.6e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS86931.1 - 8.3e-18 63.8 0.7 4.5e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 ETS86931.1 - 2.4e-09 36.5 0.1 1.3e-08 34.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS86931.1 - 5.7e-09 35.8 0.0 1.1e-06 28.5 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS86931.1 - 1.7e-08 34.6 0.0 6e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS86931.1 - 6.8e-05 21.9 1.2 0.11 11.3 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS86931.1 - 0.00034 20.9 0.1 0.67 10.4 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 ETS86931.1 - 0.00053 19.7 1.1 14 5.4 0.0 4.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.12 ETS86931.1 - 0.0032 16.5 0.0 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 ETS86931.1 - 0.0078 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 ETS86931.1 - 0.017 13.6 0.7 0.085 11.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 ETS86931.1 - 0.073 11.9 1.0 0.11 11.3 0.0 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 ETS86931.1 - 0.21 11.6 0.1 39 4.3 0.0 3.5 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase CAP PF00188.21 ETS86932.1 - 9.8e-12 45.4 1.1 1.2e-11 45.1 0.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ank_2 PF12796.2 ETS86934.1 - 4.6e-12 46.1 0.1 0.00022 21.4 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 ETS86934.1 - 3.6e-06 27.3 0.0 0.39 11.2 0.0 4.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86934.1 - 6.1e-06 25.9 3.6 50 4.5 0.0 7.6 7 1 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.1 ETS86934.1 - 0.00029 20.9 0.4 47 4.4 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank PF00023.25 ETS86934.1 - 0.00064 19.4 1.3 28 4.7 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat F-box PF00646.28 ETS86934.1 - 0.16 11.6 1.7 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 ETS86934.1 - 0.28 10.9 3.0 0.26 11.0 0.1 2.5 2 0 0 2 2 2 0 F-box-like Methyltransf_2 PF00891.13 ETS86935.1 - 4e-33 114.5 0.0 5.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 ETS86935.1 - 0.0077 16.7 0.0 0.025 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 ETS86936.1 - 3.3e-49 167.6 0.0 8.5e-49 166.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 ETS86940.1 - 5.9e-17 61.3 9.4 8.2e-13 47.7 4.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS86940.1 - 2.2e-06 26.6 17.1 4.9e-06 25.4 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 ETS86941.1 - 3.7e-22 79.0 0.0 6.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86941.1 - 1e-14 54.9 0.0 1.3e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86941.1 - 1.1e-09 38.2 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 ETS86941.1 - 4.3e-09 35.9 0.0 0.00034 19.8 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 ETS86941.1 - 2.4e-08 34.2 0.2 8.5e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 ETS86941.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 ETS86941.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 ETS86941.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family YchF-GTPase_C PF06071.8 ETS86943.1 - 1.1e-32 111.6 0.1 3.2e-32 110.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 ETS86943.1 - 1.1e-12 47.9 0.0 4.6e-12 45.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 ETS86943.1 - 0.00047 19.4 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 ETS86943.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain MobB PF03205.9 ETS86943.1 - 0.028 14.1 0.6 4 7.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 ETS86943.1 - 0.035 14.0 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 ETS86943.1 - 0.042 13.6 0.1 5.8 6.7 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_17 PF13207.1 ETS86943.1 - 0.066 14.0 0.1 0.5 11.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain CsrA PF02599.11 ETS86943.1 - 0.1 12.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Global regulator protein family PPAK PF02818.10 ETS86943.1 - 0.13 12.2 4.2 0.39 10.6 2.9 1.9 1 0 0 1 1 1 0 PPAK motif AAA_23 PF13476.1 ETS86943.1 - 0.89 9.8 6.6 11 6.3 4.6 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.9 ETS86944.1 - 1.2e-33 116.0 0.0 1.5e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 ETS86944.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.14 ETS86945.1 - 2.2e-12 47.1 0.7 3.9e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 DUF4160 PF13711.1 ETS86945.1 - 0.51 10.2 4.5 2.2 8.1 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4160) Tim44 PF04280.10 ETS86946.1 - 4.4e-33 114.3 0.0 2.9e-32 111.6 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain CT47 PF15623.1 ETS86946.1 - 0.0048 16.6 14.0 0.12 12.0 3.7 2.5 2 0 0 2 2 2 2 Cancer/testis gene family 47 DUF1768 PF08719.6 ETS86947.1 - 1.4e-46 158.0 0.0 2.3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NST1 PF13945.1 ETS86947.1 - 1 9.3 5.6 1.9 8.5 3.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2190 PF09956.4 ETS86948.1 - 0.016 14.9 0.4 0.037 13.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) Sugar_tr PF00083.19 ETS86950.1 - 2.2e-66 224.2 34.1 2.5e-66 224.0 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS86950.1 - 1.4e-22 79.9 58.6 1.7e-21 76.3 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS86950.1 - 6.5e-05 21.5 41.1 0.00018 20.0 6.6 3.7 2 2 2 4 4 4 2 MFS/sugar transport protein Glyco_hydro_3 PF00933.16 ETS86951.1 - 3.8e-63 213.2 0.0 6.1e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 ETS86951.1 - 6.4e-60 202.5 0.0 2.1e-59 200.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 ETS86951.1 - 7.8e-23 80.2 0.2 1.7e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS86951.1 - 1.7e-07 30.9 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF2188 PF09954.4 ETS86951.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2188) Methyltransf_18 PF12847.2 ETS86953.1 - 1.4e-12 48.1 0.1 3.8e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86953.1 - 8.8e-12 45.3 0.0 2.7e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86953.1 - 8.8e-12 45.0 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS86953.1 - 4.1e-11 43.2 0.0 1.9e-10 41.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86953.1 - 1.9e-10 40.5 0.0 7.4e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86953.1 - 1.6e-06 28.3 0.0 1.6e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86953.1 - 1.8e-05 24.7 0.1 3.2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS86953.1 - 3.5e-05 23.0 0.0 0.0004 19.5 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 ETS86953.1 - 6.9e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS86953.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 ETS86953.1 - 0.00069 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 ETS86953.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) 3HCDH_N PF02737.13 ETS86953.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_32 PF13679.1 ETS86953.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 ETS86954.1 - 1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS86954.1 - 2.4e-17 63.1 0.0 4.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS86954.1 - 3.4e-17 62.6 0.0 5.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS86954.1 - 3.5e-11 43.6 0.0 5.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS86954.1 - 4.9e-11 42.1 0.0 3.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 ETS86954.1 - 5.6e-11 42.0 0.0 6.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 ETS86954.1 - 6e-11 42.6 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS86954.1 - 4.4e-10 39.8 0.0 7.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS86954.1 - 6.9e-10 38.9 0.1 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETS86954.1 - 4.4e-06 26.2 0.0 8.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 ETS86954.1 - 1.5e-05 24.4 0.0 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 ETS86954.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 ETS86954.1 - 0.00019 20.2 0.0 0.00027 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 ETS86954.1 - 0.0002 21.0 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 ETS86954.1 - 0.0041 16.4 0.0 0.0077 15.5 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 ETS86954.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LCM PF04072.9 ETS86954.1 - 0.019 14.5 0.0 0.079 12.5 0.0 1.8 2 0 0 2 2 2 0 Leucine carboxyl methyltransferase NodS PF05401.6 ETS86954.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.13 ETS86954.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Nefa_Nip30_N PF10187.4 ETS86956.1 - 1.9e-21 76.1 8.9 1.9e-21 76.1 6.1 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 HAUS6_N PF14661.1 ETS86956.1 - 0.74 9.1 6.8 1.2 8.3 4.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Draxin PF15550.1 ETS86956.1 - 1.4 8.5 9.2 1.8 8.1 6.4 1.3 1 1 0 1 1 1 0 Draxin IpaD PF06511.6 ETS86956.1 - 2.8 6.8 15.0 0.76 8.7 6.5 1.9 1 1 0 2 2 2 0 Invasion plasmid antigen IpaD Bud13 PF09736.4 ETS86956.1 - 3.5 7.8 15.9 3.2 7.9 6.6 2.2 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex Ank_2 PF12796.2 ETS86957.1 - 3.7e-86 283.5 27.3 3.5e-20 72.1 0.5 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86957.1 - 1.4e-56 185.5 19.7 5.8e-06 25.8 0.0 10.6 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 ETS86957.1 - 2.2e-51 171.3 18.3 6.6e-10 39.2 0.0 8.1 2 1 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86957.1 - 5.4e-47 153.0 4.3 0.00041 20.3 0.0 10.7 10 0 0 10 10 10 10 Ankyrin repeat HET PF06985.6 ETS86957.1 - 7.6e-39 133.0 0.1 1.6e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 ETS86957.1 - 5.6e-35 118.5 14.3 8.1e-05 22.7 0.0 9.0 2 2 8 10 10 10 7 Ankyrin repeats (many copies) HET PF06985.6 ETS86958.1 - 3.2e-23 82.4 0.0 5.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Keratin_matx PF04579.7 ETS86959.1 - 0.38 11.0 4.1 0.37 11.0 2.1 1.6 1 1 0 1 1 1 0 Keratin, high-sulphur matrix protein Ank_2 PF12796.2 ETS86960.1 - 2.3e-51 172.0 6.1 6.5e-14 52.0 0.2 8.3 3 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 ETS86960.1 - 5.1e-34 114.3 22.1 4.5e-06 26.2 0.1 14.1 14 1 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 ETS86960.1 - 2.1e-33 114.0 8.3 3.7e-07 30.4 0.0 10.4 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS86960.1 - 7e-31 103.2 14.1 1.1e-05 25.1 0.0 14.5 15 1 1 16 16 16 8 Ankyrin repeat Ank_5 PF13857.1 ETS86960.1 - 4.8e-21 74.3 10.1 0.035 14.3 0.0 11.8 9 3 4 13 13 13 6 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 ETS86960.1 - 0.011 15.2 0.0 1 8.8 0.0 3.7 3 1 1 4 4 4 0 Shigella flexneri OspC protein Methyltransf_6 PF03737.10 ETS86961.1 - 5.7e-27 94.4 0.0 9.2e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase SGL PF08450.7 ETS86961.1 - 5.6e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Amidohydro_2 PF04909.9 ETS86962.1 - 2.2e-17 63.5 0.3 1.7e-16 60.6 0.2 2.0 1 1 0 1 1 1 1 Amidohydrolase Mycobact_memb PF05423.8 ETS86962.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein Mito_carr PF00153.22 ETS86963.1 - 1.5e-49 165.6 5.1 4.6e-17 61.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4574 PF15141.1 ETS86963.1 - 0.025 14.2 0.1 0.073 12.8 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4574) PT-VENN PF04829.8 ETS86963.1 - 1.5 8.4 12.7 5.3 6.6 0.2 3.4 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Fungal_trans PF04082.13 ETS86964.1 - 3.1e-12 45.9 0.2 1.1e-11 44.1 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86964.1 - 9.1e-10 38.2 8.9 1.6e-09 37.5 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.15 ETS86965.1 - 3.1e-145 484.2 0.0 1.3e-144 482.2 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 ETS86965.1 - 1.2e-36 125.7 0.0 2.3e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Mu-like_Com PF10122.4 ETS86965.1 - 0.015 14.3 0.4 0.079 12.0 0.1 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF521 PF04412.8 ETS86965.1 - 0.037 12.5 0.0 0.063 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MFS_1 PF07690.11 ETS86966.1 - 3.3e-38 131.3 19.8 3.3e-38 131.3 13.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.19 ETS86966.1 - 0.21 10.9 0.1 0.21 10.9 0.0 2.9 2 1 1 3 3 3 0 Fatty acid desaturase HATPase_c PF02518.21 ETS86967.1 - 2e-20 72.5 0.0 4.2e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS86967.1 - 1.1e-17 63.9 0.0 5.9e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 ETS86967.1 - 1.7e-13 50.3 0.1 5.4e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 ETS86967.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MIG-14_Wnt-bd PF06664.7 ETS86970.1 - 0.044 12.6 1.0 0.049 12.4 0.1 1.4 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Alg14 PF08660.6 ETS86971.1 - 0.092 12.7 1.7 0.11 12.5 1.2 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Lig_chan PF00060.21 ETS86971.1 - 1.1 8.9 5.5 2.1 8.0 3.8 1.5 1 1 0 1 1 1 0 Ligand-gated ion channel DUF1628 PF07790.6 ETS86971.1 - 1.3 9.8 4.7 3.3 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) MerC PF03203.9 ETS86971.1 - 3.4 8.0 9.3 1.4 9.2 1.7 2.1 1 1 1 2 2 2 0 MerC mercury resistance protein FAD_binding_4 PF01565.18 ETS86972.1 - 6.6e-23 80.7 1.1 8.4e-23 80.3 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 ETS86972.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Fungal_trans_2 PF11951.3 ETS86973.1 - 0.00016 20.4 0.4 0.00022 19.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3808 PF10300.4 ETS86973.1 - 0.044 12.3 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) AstB PF04996.7 ETS86973.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase DUF4481 PF14800.1 ETS86974.1 - 4.2 6.1 5.2 6.9 5.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Sulfatase PF00884.18 ETS86975.1 - 4.7e-64 216.5 2.5 6.1e-64 216.1 1.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS86975.1 - 1.3e-05 24.7 3.7 0.00012 21.5 2.6 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 ETS86975.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily MFS_1 PF07690.11 ETS86976.1 - 1.6e-42 145.4 49.7 2.9e-34 118.3 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS86976.1 - 3.6e-09 35.7 10.0 3.6e-09 35.7 6.9 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 ETS86976.1 - 0.00012 20.3 12.7 0.00012 20.3 8.8 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3188 PF11384.3 ETS86976.1 - 7.4 6.2 8.2 17 5.0 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) Fungal_trans PF04082.13 ETS86977.1 - 1.3e-19 70.1 0.6 1.8e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86977.1 - 9.8e-05 22.1 11.1 0.00021 21.1 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P3A PF08727.6 ETS86977.1 - 0.1 11.9 0.0 8.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Poliovirus 3A protein like MFS_1 PF07690.11 ETS86978.1 - 3.4e-26 91.8 28.7 3.4e-26 91.8 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UCR_UQCRX_QCR9 PF05365.7 ETS86978.1 - 0.038 13.6 1.1 0.086 12.4 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Fungal_trans PF04082.13 ETS86979.1 - 1.1e-22 80.1 3.7 1.5e-22 79.6 1.7 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS86979.1 - 6.4e-06 25.9 5.0 1.2e-05 25.1 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_trans_3N PF02885.12 ETS86979.1 - 0.12 12.0 0.2 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Amidase PF01425.16 ETS86980.1 - 2.9e-88 296.6 0.1 4.3e-88 296.0 0.1 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 ETS86980.1 - 9.7e-83 277.5 0.0 1.5e-82 276.9 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 ETS86980.1 - 6.1e-63 211.9 0.1 1.1e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 ETS86980.1 - 1.1e-36 125.2 0.0 2.5e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 ETS86980.1 - 4.2e-34 117.7 0.0 1.3e-33 116.2 0.0 1.8 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 ETS86980.1 - 7.1e-34 116.0 0.0 1.7e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 ETS86980.1 - 2.4e-13 49.5 0.2 6.2e-13 48.1 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 ETS86980.1 - 6.4e-13 48.5 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 ETS86980.1 - 6.8e-13 48.7 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 ETS86980.1 - 1.9e-12 46.5 0.0 2.5e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 ETS86980.1 - 3.2e-08 33.1 0.1 0.00041 19.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 ETS86980.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 ETS86980.1 - 0.00041 19.7 0.0 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 ETS86980.1 - 0.0014 17.9 0.1 0.0071 15.6 0.0 2.0 1 1 0 1 1 1 1 HlyD family secretion protein HlyD_3 PF13437.1 ETS86980.1 - 0.0034 17.7 0.0 0.18 12.1 0.1 2.8 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 ETS86980.1 - 0.35 9.9 0.0 0.74 8.9 0.0 1.5 1 1 0 1 1 1 0 HlyD family secretion protein WSC PF01822.14 ETS86981.1 - 2e-57 191.0 82.2 3.1e-19 68.6 12.4 9.6 6 1 2 9 9 9 5 WSC domain PAN_4 PF14295.1 ETS86981.1 - 1.1e-16 60.2 13.5 2e-07 30.5 0.4 8.8 8 1 1 9 9 9 3 PAN domain Abhydrolase_5 PF12695.2 ETS86981.1 - 2.4e-06 27.3 0.1 8.6e-06 25.5 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAN_3 PF08277.7 ETS86981.1 - 4.2e-05 23.0 40.3 0.0017 17.9 0.6 7.2 7 1 0 7 7 7 3 PAN-like domain Abhydrolase_6 PF12697.2 ETS86981.1 - 0.00033 20.5 0.0 0.00079 19.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aa_trans PF01490.13 ETS86982.1 - 9.1e-60 202.2 35.5 1e-59 202.0 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CD99L2 PF12301.3 ETS86982.1 - 0.17 11.5 0.4 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 PgaD PF13994.1 ETS86982.1 - 0.41 10.1 3.9 1.3 8.5 2.7 1.9 1 0 0 1 1 1 0 PgaD-like protein DUF1282 PF06930.7 ETS86983.1 - 0.023 14.3 0.3 0.032 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DcuC PF03606.10 ETS86983.1 - 0.15 10.2 1.1 0.17 10.0 0.0 1.5 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier CorA PF01544.13 ETS86983.1 - 1.3 8.0 5.7 3.5 6.5 3.9 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 ETS86984.1 - 6e-39 133.7 0.0 5.3e-34 117.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86984.1 - 2.8e-22 79.0 0.0 3.7e-21 75.3 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 ETS86984.1 - 0.0015 18.3 0.1 0.018 14.8 0.1 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS86984.1 - 0.012 15.2 0.0 0.048 13.2 0.0 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase TPR_10 PF13374.1 ETS86985.1 - 1.5e-57 190.0 3.0 6.5e-08 32.2 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 ETS86985.1 - 3.2e-52 174.3 12.0 6.8e-11 41.9 0.0 6.7 2 1 4 7 7 7 7 Tetratricopeptide repeat Pkinase PF00069.20 ETS86985.1 - 4.5e-21 75.1 0.0 8.6e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS86985.1 - 7.5e-16 57.9 0.0 2.1e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 ETS86985.1 - 2.8e-11 42.9 0.5 0.0087 15.6 0.0 5.6 3 2 2 5 5 5 3 TPR repeat TPR_7 PF13176.1 ETS86985.1 - 2.7e-09 36.1 10.0 0.55 10.1 0.0 7.2 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 ETS86985.1 - 1.9e-08 33.5 8.6 0.92 9.5 0.3 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS86985.1 - 7.2e-08 32.4 4.3 4.8 8.0 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS86985.1 - 2e-07 31.2 2.5 0.17 12.2 0.1 4.7 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 ETS86985.1 - 1.3e-06 27.7 4.4 3.2 7.7 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 ETS86985.1 - 4.3e-06 26.0 6.7 0.95 9.1 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 ETS86985.1 - 2.4e-05 24.3 7.2 0.75 10.4 0.1 6.2 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 ETS86985.1 - 2.7e-05 24.2 0.0 0.52 10.4 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 ETS86985.1 - 0.00015 22.3 4.9 2.3 8.9 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 ETS86985.1 - 0.0011 19.0 1.4 41 4.7 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Kdo PF06293.9 ETS86985.1 - 0.0085 15.1 0.0 0.024 13.7 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_3 PF07720.7 ETS86985.1 - 0.74 9.6 4.0 8 6.3 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Glyco_transf_25 PF01755.12 ETS86986.1 - 0.003 17.2 0.2 0.02 14.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Podoplanin PF05808.6 ETS86987.1 - 0.00061 19.3 5.1 0.0013 18.3 3.5 1.4 1 0 0 1 1 1 1 Podoplanin Yip1 PF04893.12 ETS86987.1 - 0.012 15.1 0.5 0.022 14.2 0.3 1.4 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 ETS86987.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_YMGG PF13441.1 ETS86987.1 - 0.31 10.5 6.1 0.66 9.5 4.2 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Phage_Coat_B PF05356.6 ETS86987.1 - 3.3 7.4 7.7 1 9.1 1.8 2.4 1 1 1 2 2 2 0 Phage Coat protein B HET PF06985.6 ETS86990.1 - 6.5e-24 84.6 0.0 1.5e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1765 PF08578.5 ETS86994.1 - 5.2e-43 146.1 3.6 8.7e-43 145.3 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Brix PF04427.13 ETS86995.1 - 2.5e-36 125.1 0.2 3.4e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain EURL PF06937.6 ETS86995.1 - 0.018 14.5 0.3 0.025 14.0 0.2 1.2 1 0 0 1 1 1 0 EURL protein MscS_TM PF12794.2 ETS86996.1 - 0.0052 15.4 0.0 0.0099 14.5 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 DUF1772 PF08592.6 ETS86996.1 - 0.04 13.6 0.8 0.15 11.8 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Sulfate_transp PF00916.15 ETS86996.1 - 0.054 12.5 0.2 0.096 11.6 0.2 1.4 1 0 0 1 1 1 0 Sulfate transporter family VKOR PF07884.9 ETS86996.1 - 0.22 11.3 2.8 0.54 10.1 1.9 1.6 1 1 0 1 1 1 0 Vitamin K epoxide reductase family adh_short PF00106.20 ETS86997.1 - 2.1e-21 76.5 0.5 2.7e-21 76.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86997.1 - 2.1e-20 73.5 0.0 2.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86997.1 - 4.5e-08 32.9 1.9 2.7e-07 30.4 1.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS86997.1 - 0.014 14.8 0.2 0.033 13.6 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS86997.1 - 0.024 14.6 1.0 0.67 9.9 0.4 2.3 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 ETS86997.1 - 0.086 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 ETS86998.1 - 3.4e-28 98.6 2.9 8.4e-28 97.3 2.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS86998.1 - 1.7e-13 50.8 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS86998.1 - 2.7e-11 43.4 2.5 3.1e-10 40.0 1.7 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS86998.1 - 4.1e-07 30.1 0.1 1.1e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS86998.1 - 4.8e-06 26.1 0.2 1.9e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS86998.1 - 0.0076 15.1 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.8 ETS86998.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) 3Beta_HSD PF01073.14 ETS86998.1 - 0.0089 14.7 0.1 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 ETS86998.1 - 0.032 13.8 0.3 0.05 13.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 ETS86998.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 ETS86998.1 - 0.077 11.9 0.5 3.3 6.5 0.1 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 ETS86998.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 ETS86998.1 - 0.25 11.1 0.9 0.45 10.3 0.6 1.4 1 0 0 1 1 1 0 ThiF family Crystall PF00030.14 ETS86999.1 - 0.07 13.0 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 Beta/Gamma crystallin Indigoidine_A PF04227.7 ETS87001.1 - 3e-102 341.7 0.1 5e-102 341.0 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 ETS87001.1 - 7.1e-26 91.0 0.0 8.7e-25 87.4 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.27 ETS87002.1 - 2.1e-08 33.7 0.0 0.031 14.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat AICARFT_IMPCHas PF01808.13 ETS87004.1 - 8e-111 370.1 0.0 1.1e-110 369.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 ETS87004.1 - 1.1e-23 82.9 0.0 2.3e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Sld5 PF05916.6 ETS87005.1 - 2.9e-12 46.8 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.15 ETS87006.1 - 1.2e-32 113.0 1.2 2.7e-32 111.8 0.8 1.6 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 ETS87006.1 - 3.3e-19 68.4 0.0 1.2e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.16 ETS87006.1 - 4.8e-09 35.6 0.0 9.2e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain GST_C PF00043.20 ETS87007.1 - 0.00025 20.9 0.2 0.00054 19.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 ETS87008.1 - 9.9e-48 162.6 21.2 9.9e-48 162.6 14.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS87008.1 - 3.7e-14 52.1 18.4 1.6e-13 50.0 12.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 ETS87008.1 - 0.0066 14.5 0.1 0.0066 14.5 0.1 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family SAYSvFN PF10260.4 ETS87008.1 - 0.026 14.2 1.9 0.97 9.2 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) BT1 PF03092.11 ETS87008.1 - 0.03 13.0 1.0 0.04 12.6 0.7 1.2 1 0 0 1 1 1 0 BT1 family DUF1144 PF06610.8 ETS87009.1 - 0.017 14.9 0.9 0.022 14.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1144) Aa_trans PF01490.13 ETS87009.1 - 0.037 12.5 3.1 0.048 12.1 2.1 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Halogen_Hydrol PF10112.4 ETS87009.1 - 0.21 10.9 2.5 0.26 10.6 1.7 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Filament PF00038.16 ETS87011.1 - 0.0008 18.9 12.0 0.0008 18.9 8.3 6.6 4 2 0 4 4 4 3 Intermediate filament protein PLAC9 PF15205.1 ETS87011.1 - 0.0047 17.1 0.1 0.029 14.6 0.0 2.5 1 0 0 1 1 1 1 Placenta-specific protein 9 IncA PF04156.9 ETS87011.1 - 0.0081 15.7 7.3 0.0081 15.7 5.1 7.0 5 2 2 7 7 7 3 IncA protein Baculo_PEP_C PF04513.7 ETS87011.1 - 1.3 8.8 29.7 0.28 11.0 1.8 6.0 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 ETS87011.1 - 3.3 6.7 30.9 1.4 7.9 0.8 5.2 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Hydantoinase_A PF01968.13 ETS87012.1 - 1.9e-85 286.4 8.0 2.2e-84 283.0 1.8 2.5 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 ETS87012.1 - 8.3e-66 222.2 0.0 1.4e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 ETS87012.1 - 1.8e-47 161.0 0.3 1.1e-44 151.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 ETS87012.1 - 3.6e-05 22.2 2.7 0.0073 14.6 0.3 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 ETS87012.1 - 0.0084 15.4 0.5 0.39 9.9 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.12 ETS87012.1 - 0.11 12.2 0.1 3.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Transposase DUF3871 PF12987.2 ETS87012.1 - 0.13 10.9 0.0 0.28 9.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) DUF4051 PF13260.1 ETS87013.1 - 0.62 9.4 2.9 1.1 8.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) UPF0370 PF13980.1 ETS87013.1 - 1.3 8.8 5.2 2 8.2 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) hDGE_amylase PF14701.1 ETS87015.1 - 9.3e-177 588.1 0.0 1.2e-176 587.7 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 ETS87015.1 - 2.8e-115 384.9 0.2 7.3e-115 383.6 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 ETS87015.1 - 2.8e-86 288.9 0.0 5.2e-86 288.0 0.0 1.5 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 ETS87015.1 - 1.5e-26 92.0 0.0 3.6e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 ETS87015.1 - 0.00062 19.2 0.1 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain 2-Hacid_dh PF00389.25 ETS87015.1 - 0.071 12.5 0.0 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RIX1 PF08167.7 ETS87015.1 - 0.096 12.3 0.1 14 5.2 0.0 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis NAD_Gly3P_dh_N PF01210.18 ETS87016.1 - 3.7e-46 156.7 0.0 7.1e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 ETS87016.1 - 1.6e-40 138.2 0.2 2.3e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.1 ETS87017.1 - 0.0048 16.9 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family TPP_enzyme_N PF02776.13 ETS87018.1 - 1e-55 187.8 0.1 3.2e-55 186.2 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 ETS87018.1 - 1.3e-49 167.7 0.5 3.2e-48 163.1 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 ETS87018.1 - 5.4e-37 126.5 0.3 2.4e-36 124.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 ETS87018.1 - 0.037 13.5 0.1 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NeA_P2 PF12312.3 ETS87019.1 - 0.011 15.0 1.0 0.011 15.0 0.7 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Carb_kinase PF01256.12 ETS87020.1 - 6.7e-56 189.2 0.1 8.3e-56 188.9 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 ETS87020.1 - 0.0042 16.3 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 ETS87020.1 - 0.039 13.1 0.0 0.073 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.20 ETS87021.1 - 5.5e-70 235.2 0.0 8e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 ETS87021.1 - 1.5e-26 93.1 1.0 3.3e-26 91.9 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 ETS87021.1 - 1e-15 57.6 2.7 2.7e-15 56.3 1.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 ETS87021.1 - 0.0057 16.5 0.8 0.018 14.8 0.6 1.9 1 1 0 1 1 1 1 HAS barrel domain Rax2 PF12768.2 ETS87022.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 ETS87022.1 - 0.032 13.5 0.5 0.12 11.6 0.3 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Proteasom_Rpn13 PF04683.8 ETS87024.1 - 6.3e-27 93.4 0.0 9.6e-27 92.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 ETS87025.1 - 1.2e-36 125.2 0.2 1.2e-36 125.2 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.10 ETS87026.1 - 2.4e-226 752.1 0.0 2.8e-226 751.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 ETS87026.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 2C_adapt PF08793.5 ETS87026.1 - 0.15 11.9 1.1 0.31 10.9 0.8 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain SKI PF01202.17 ETS87027.1 - 1.4e-12 47.8 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 ETS87027.1 - 9.1e-12 45.8 0.0 1.6e-11 45.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS87027.1 - 1.1e-11 44.7 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS87027.1 - 1.4e-09 38.3 0.1 5.4e-09 36.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain Rad17 PF03215.10 ETS87027.1 - 2.3e-05 23.2 0.0 3.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 ETS87027.1 - 0.00047 20.1 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 ETS87027.1 - 0.00057 20.0 0.0 0.0048 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS87027.1 - 0.0009 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 ETS87027.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 ETS87027.1 - 0.0013 18.6 0.6 0.049 13.5 0.0 2.7 2 1 0 3 3 2 1 Cytidylate kinase-like family Mg_chelatase PF01078.16 ETS87027.1 - 0.0021 17.2 0.1 0.0051 16.0 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 ETS87027.1 - 0.0024 18.0 0.1 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS87027.1 - 0.0042 17.0 0.0 0.0072 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 ETS87027.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 ETS87027.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 ETS87027.1 - 0.0092 15.5 0.1 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS87027.1 - 0.0098 16.1 0.0 0.025 14.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.15 ETS87027.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase T2SE PF00437.15 ETS87027.1 - 0.016 14.1 0.1 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 ETS87027.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 ETS87027.1 - 0.023 14.6 0.0 0.073 12.9 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETS87027.1 - 0.033 13.7 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 ETS87027.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 ETS87027.1 - 0.037 13.4 0.2 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 MutS domain V CoaE PF01121.15 ETS87027.1 - 0.041 13.2 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase NTPase_1 PF03266.10 ETS87027.1 - 0.052 13.2 0.1 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 ETS87027.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 ETS87027.1 - 0.059 12.5 0.1 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 ETS87027.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 ETS87027.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain 2-oxoacid_dh PF00198.18 ETS87028.1 - 2e-78 262.8 0.8 2.8e-78 262.3 0.5 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 ETS87028.1 - 1.9e-16 59.4 0.1 3.5e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 ETS87028.1 - 6.1e-12 44.9 0.1 1.7e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain BEX PF04538.7 ETS87028.1 - 0.02 15.0 1.4 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Brain expressed X-linked like family ATP-synt_10 PF05176.9 ETS87029.1 - 2.7e-79 266.0 0.0 3.5e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein zf-CCHC PF00098.18 ETS87031.1 - 4.7e-06 26.2 1.0 7.4e-06 25.6 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 ETS87031.1 - 0.0086 15.7 0.5 0.018 14.7 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DDHD PF02862.12 ETS87031.1 - 0.011 15.6 19.9 0.014 15.1 13.8 1.4 1 0 0 1 1 1 0 DDHD domain PPP4R2 PF09184.6 ETS87031.1 - 0.018 14.5 36.9 0.021 14.4 25.6 1.0 1 0 0 1 1 1 0 PPP4R2 SprA-related PF12118.3 ETS87031.1 - 0.022 14.1 40.0 0.028 13.7 27.7 1.2 1 0 0 1 1 1 0 SprA-related family RskA PF10099.4 ETS87031.1 - 0.026 14.2 0.9 0.034 13.8 0.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.5 ETS87031.1 - 0.033 12.4 36.8 0.032 12.4 25.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CENP-T PF15511.1 ETS87031.1 - 0.058 12.6 20.1 0.062 12.5 14.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 ETS87031.1 - 0.13 10.1 31.2 0.14 10.0 21.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 ETS87031.1 - 0.15 11.2 23.4 0.16 11.1 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCDC71L PF15374.1 ETS87031.1 - 0.18 11.0 16.9 0.2 10.9 11.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L FLO_LFY PF01698.11 ETS87031.1 - 0.25 10.1 25.6 0.28 9.9 17.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 ETS87031.1 - 0.34 10.2 42.1 0.39 10.0 29.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF913 PF06025.7 ETS87031.1 - 0.36 9.5 12.4 0.45 9.2 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.7 ETS87031.1 - 0.37 9.8 34.2 0.54 9.3 23.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC27 PF09507.5 ETS87031.1 - 0.53 9.4 35.9 0.6 9.2 24.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2201_N PF13203.1 ETS87031.1 - 0.59 9.2 26.8 0.67 9.0 18.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CAF-1_p150 PF11600.3 ETS87031.1 - 1 8.7 51.6 1.2 8.4 35.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4175 PF13779.1 ETS87031.1 - 1.2 6.7 47.5 1.2 6.7 32.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1501 PF07394.7 ETS87031.1 - 1.4 7.6 16.8 1.6 7.4 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sporozoite_P67 PF05642.6 ETS87031.1 - 1.4 6.6 14.1 1.7 6.4 9.8 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 ETS87031.1 - 1.5 7.2 40.4 1.7 7.0 28.0 1.0 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 ETS87031.1 - 1.5 6.9 37.6 1.6 6.8 26.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 ETS87031.1 - 3 7.6 34.6 3.7 7.3 24.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pilt PF15453.1 ETS87031.1 - 3.5 7.2 28.3 4.1 7.0 19.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions IncA PF04156.9 ETS87031.1 - 3.8 7.0 36.3 4.5 6.8 25.2 1.2 1 0 0 1 1 1 0 IncA protein RNase_H2-Ydr279 PF09468.5 ETS87031.1 - 4.2 6.4 21.2 5.8 6.0 14.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Cyclin_C PF02984.14 ETS87031.1 - 5.3 6.9 10.4 7 6.6 7.2 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Peptidase_S64 PF08192.6 ETS87031.1 - 6 5.0 17.3 6.2 5.0 12.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.9 ETS87031.1 - 6.3 4.7 30.6 9.1 4.1 21.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Gag_spuma PF03276.9 ETS87031.1 - 6.9 4.8 30.0 8.3 4.5 20.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PIH1 PF08190.7 ETS87031.1 - 7.9 5.8 30.8 9.2 5.5 21.4 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Med19 PF10278.4 ETS87031.1 - 7.9 6.1 26.9 11 5.6 18.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AAA_11 PF13086.1 ETS87031.1 - 8.3 5.9 26.7 10 5.6 18.5 1.1 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 ETS87033.1 - 7.1e-22 78.0 8.1 9.5e-22 77.6 5.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87033.1 - 2.4e-13 50.4 0.2 2.9e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87033.1 - 2.1e-06 27.5 5.4 3.4e-06 26.8 3.7 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS87033.1 - 1.3e-05 25.2 0.3 1.8e-05 24.7 0.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 ETS87033.1 - 8.2e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 ETS87033.1 - 0.0035 16.8 0.3 0.011 15.2 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.8 ETS87033.1 - 0.013 14.7 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Clusterin PF01093.12 ETS87034.1 - 0.0065 15.3 0.0 0.0076 15.0 0.0 1.0 1 0 0 1 1 1 1 Clusterin PAP2 PF01569.16 ETS87035.1 - 1.3e-21 76.5 7.1 1.5e-21 76.4 2.5 2.7 2 1 0 2 2 2 1 PAP2 superfamily Rhomboid PF01694.17 ETS87035.1 - 1.4 8.9 13.1 1.7 8.6 0.1 3.0 4 0 0 4 4 4 0 Rhomboid family Polysacc_deac_1 PF01522.16 ETS87036.1 - 5.6e-28 97.0 0.0 9.2e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 ETS87036.1 - 3.2e-16 59.0 36.2 2.1e-08 33.9 13.5 2.5 2 0 0 2 2 2 2 Chitin recognition protein Med3 PF11593.3 ETS87036.1 - 7.5 5.6 21.4 14 4.7 14.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal STT3 PF02516.9 ETS87038.1 - 7.8e-130 434.0 41.4 1.2e-124 417.0 27.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF1772 PF08592.6 ETS87039.1 - 1.9e-18 66.5 4.5 8.4e-18 64.4 3.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) CDC45 PF02724.9 ETS87042.1 - 1.5 6.7 6.2 1.6 6.6 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pro_racemase PF05544.6 ETS87043.1 - 2.5e-122 407.7 1.1 2.8e-122 407.6 0.7 1.0 1 0 0 1 1 1 1 Proline racemase Spc7 PF08317.6 ETS87044.1 - 0.0072 15.0 10.2 0.0084 14.8 7.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1202 PF06717.6 ETS87044.1 - 0.0093 15.2 0.7 0.021 14.0 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1202) AAA_13 PF13166.1 ETS87044.1 - 0.012 14.0 4.2 0.013 13.9 2.9 1.0 1 0 0 1 1 1 0 AAA domain DUF2608 PF11019.3 ETS87044.1 - 0.014 14.4 0.6 0.015 14.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF1664 PF07889.7 ETS87044.1 - 0.016 15.0 1.3 0.016 15.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 ETS87044.1 - 0.018 14.8 10.4 0.032 14.0 7.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ORF6N PF10543.4 ETS87044.1 - 0.03 14.3 1.6 0.053 13.5 1.1 1.5 1 0 0 1 1 1 0 ORF6N domain DUF869 PF05911.6 ETS87044.1 - 0.068 11.3 11.1 0.078 11.1 7.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Fez1 PF06818.10 ETS87044.1 - 0.08 12.9 9.5 0.098 12.6 6.6 1.2 1 0 0 1 1 1 0 Fez1 Atg14 PF10186.4 ETS87044.1 - 0.1 11.5 9.2 0.12 11.2 6.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 ETS87044.1 - 0.13 12.0 10.2 0.18 11.5 2.3 2.6 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.8 ETS87044.1 - 0.26 10.3 3.7 0.29 10.1 2.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 ETS87044.1 - 0.27 10.8 9.8 0.4 10.2 6.8 1.3 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 ETS87044.1 - 0.33 10.7 4.7 0.74 9.5 3.2 1.7 1 1 0 1 1 1 0 Laminin Domain II Rop-like PF05082.8 ETS87044.1 - 0.85 9.1 8.3 0.39 10.2 2.5 2.4 3 0 0 3 3 2 0 Rop-like CENP-Q PF13094.1 ETS87044.1 - 1 9.3 11.0 0.81 9.7 6.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_MT_bd PF06657.8 ETS87044.1 - 1 9.3 12.2 46 4.0 8.4 3.2 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF2018 PF09442.5 ETS87044.1 - 1.9 9.1 6.4 0.71 10.4 1.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2018) Med28 PF11594.3 ETS87044.1 - 2.3 8.5 11.1 8.5 6.6 7.7 1.8 1 1 0 1 1 1 0 Mediator complex subunit 28 YlbD_coat PF14071.1 ETS87044.1 - 2.4 8.2 5.0 4 7.5 2.5 1.9 1 1 1 2 2 2 0 Putative coat protein Sec8_exocyst PF04048.9 ETS87044.1 - 2.8 7.5 7.5 2.4 7.7 0.4 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Spc24 PF08286.6 ETS87044.1 - 3.7 7.2 8.7 1.6 8.4 2.0 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Lge1 PF11488.3 ETS87044.1 - 5.4 7.2 10.1 72 3.6 7.0 2.6 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 UPF0242 PF06785.6 ETS87044.1 - 5.9 5.4 12.0 7 5.2 8.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Fib_alpha PF08702.5 ETS87044.1 - 7.5 6.6 11.9 24 5.0 0.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 ETS87044.1 - 8.4 6.3 9.3 1.5 8.7 1.3 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.9 ETS87044.1 - 8.7 5.9 14.1 6.4 6.3 8.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) zf-Tim10_DDP PF02953.10 ETS87045.1 - 0.016 14.4 2.0 0.016 14.4 1.4 2.5 1 1 2 3 3 3 0 Tim10/DDP family zinc finger Aldolase_II PF00596.16 ETS87046.1 - 3.4e-40 137.6 0.0 4.3e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 ETS87047.1 - 1.7e-159 530.3 19.1 2.1e-159 530.0 13.2 1.1 1 0 0 1 1 1 1 Calreticulin family Aminotran_1_2 PF00155.16 ETS87048.1 - 9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 ETS87048.1 - 6.5e-07 28.2 0.0 1.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Med14 PF08638.6 ETS87050.1 - 5.1e-67 224.9 0.0 1.3e-66 223.5 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit MED14 MFS_1 PF07690.11 ETS87052.1 - 1.4e-27 96.4 30.5 6.6e-27 94.1 21.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 ETS87053.1 - 2.1e-41 141.2 2.6 3.3e-41 140.6 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 COX8 PF02285.10 ETS87053.1 - 0.048 13.1 1.0 0.36 10.4 0.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DUF2135 PF09906.4 ETS87053.1 - 0.086 12.8 0.3 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) LysM PF01476.15 ETS87054.1 - 6.6e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain RCR PF12273.3 ETS87054.1 - 2.6 8.6 6.8 17 5.9 2.2 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red tRNA-synt_His PF13393.1 ETS87055.1 - 1.2e-41 142.7 0.0 2.5e-35 122.0 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 ETS87055.1 - 1.9e-19 69.8 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS87055.1 - 1.9e-14 53.3 0.0 3.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 ETS87055.1 - 0.00017 20.5 0.2 0.0068 15.2 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 ETS87057.1 - 5.7e-71 238.7 0.0 7.5e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87057.1 - 2.7e-34 118.4 0.1 6.1e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS87057.1 - 4.5e-05 22.5 0.0 6.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS87057.1 - 0.00057 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 ETS87057.1 - 0.0015 17.9 0.0 0.0042 16.4 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 ETS87057.1 - 0.15 11.7 0.9 1.1 8.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family UQ_con PF00179.21 ETS87058.1 - 2.5e-27 95.0 0.0 2.9e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 ETS87058.1 - 4.1e-08 33.0 0.0 5.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 ETS87058.1 - 1.2e-05 25.1 0.1 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 ETS87058.1 - 0.00045 19.8 0.1 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.6 ETS87058.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 CBM_4_9 PF02018.12 ETS87058.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain Sec1 PF00995.18 ETS87059.1 - 1.5e-142 476.1 0.0 1.7e-142 475.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3772 PF12607.3 ETS87059.1 - 0.41 10.3 3.3 4.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Amino_oxidase PF01593.19 ETS87061.1 - 2.1e-84 284.1 0.5 1.3e-83 281.5 0.3 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS87061.1 - 1.6e-08 34.4 0.2 3.7e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.12 ETS87061.1 - 6.8e-08 32.5 0.1 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain HMG_box_2 PF09011.5 ETS87061.1 - 2.2e-06 27.9 5.3 2.2e-06 27.9 3.7 2.1 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.14 ETS87061.1 - 3.2e-06 27.2 6.0 3.2e-06 27.2 4.2 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 ETS87061.1 - 0.011 14.6 0.7 0.051 12.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS87061.1 - 0.015 15.0 0.3 1.5 8.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding ATP-synt PF00231.14 ETS87062.1 - 1e-69 235.1 0.2 1.2e-69 234.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 ETS87063.1 - 3e-97 324.1 5.4 3e-97 324.1 3.7 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 ETS87063.1 - 8.6e-83 277.0 1.2 8.6e-83 277.0 0.8 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 ETS87063.1 - 4.5e-31 106.3 0.4 1.6e-30 104.5 0.3 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain CorA PF01544.13 ETS87064.1 - 6.2e-42 143.6 2.8 1e-40 139.6 2.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 ETS87065.1 - 1.6e-29 101.8 0.2 1.6e-29 101.8 0.1 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 ETS87065.1 - 9.7e-22 76.3 0.0 1.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87065.1 - 6.1e-16 58.1 0.0 1.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87065.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 ETS87065.1 - 8e-08 31.4 8.8 2.3e-07 29.9 6.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.1 ETS87065.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 Band_7 PF01145.20 ETS87066.1 - 3.8e-24 85.5 1.5 5.6e-24 85.0 1.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 ETS87066.1 - 0.021 14.3 0.2 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus ubiquitin PF00240.18 ETS87067.1 - 5.4e-25 86.5 0.2 6e-25 86.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 ETS87067.1 - 1.8e-15 56.3 0.2 2e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 ETS87067.1 - 0.00011 22.4 0.1 0.00031 20.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 ETS87068.1 - 2e-21 76.3 0.1 4.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SMP PF04927.7 ETS87069.1 - 7.8e-05 22.5 2.4 0.00011 22.0 1.7 1.2 1 0 0 1 1 1 1 Seed maturation protein Elf1 PF05129.8 ETS87070.1 - 0.028 14.0 8.7 0.037 13.7 1.4 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like RRN7 PF11781.3 ETS87070.1 - 0.098 12.1 6.3 0.34 10.4 4.4 1.9 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 ETS87070.1 - 1.6 8.6 12.0 0.43 10.4 2.5 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Rad21_Rec8_N PF04825.8 ETS87072.1 - 5e-39 132.6 0.0 9e-39 131.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 ETS87072.1 - 8.2e-09 34.5 0.2 1.8e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 ETS87072.1 - 0.00064 19.3 0.1 0.017 14.7 0.0 2.6 3 0 0 3 3 3 1 ScpA/B protein E1-E2_ATPase PF00122.15 ETS87073.1 - 4.2e-73 245.1 0.4 9.1e-73 244.0 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS87073.1 - 1.3e-44 151.9 2.4 2.9e-44 150.7 1.7 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS87073.1 - 1e-33 117.6 0.0 1.4e-32 113.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 ETS87073.1 - 9.5e-19 66.6 0.0 2.1e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS87073.1 - 1.9e-14 54.3 0.0 4.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS87073.1 - 1e-13 51.0 0.0 1.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 ETS87073.1 - 0.00016 21.3 0.5 0.0013 18.4 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rsd_AlgQ PF04353.8 ETS87074.1 - 0.022 14.4 2.4 0.094 12.4 0.8 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2541 PF10807.3 ETS87074.1 - 0.036 13.8 0.1 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) DUF1664 PF07889.7 ETS87074.1 - 0.58 9.9 5.2 0.75 9.6 3.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) G-patch PF01585.18 ETS87075.1 - 3.5e-06 26.7 0.0 1.1e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 G-patch domain Utp14 PF04615.8 ETS87075.1 - 0.0015 16.8 45.3 0.0019 16.4 31.4 1.2 1 0 0 1 1 1 1 Utp14 protein Asp-B-Hydro_N PF05279.6 ETS87075.1 - 0.17 11.6 35.9 0.23 11.2 24.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1427 PF07235.6 ETS87075.1 - 0.19 11.8 0.1 0.19 11.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1427) MIP-T3 PF10243.4 ETS87075.1 - 0.44 8.9 59.8 0.66 8.3 41.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 ETS87075.1 - 0.46 9.6 53.1 0.69 9.0 36.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.6 ETS87075.1 - 0.53 8.4 38.9 0.65 8.1 27.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.8 ETS87075.1 - 1.3 8.1 41.1 2.9 7.0 28.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIF_alpha PF05793.7 ETS87075.1 - 2.6 6.2 59.4 4.2 5.6 41.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PLRV_ORF5 PF01690.12 ETS87075.1 - 9.1 5.2 31.3 15 4.6 21.7 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Zn_clus PF00172.13 ETS87077.1 - 9.8e-07 28.5 9.5 2.5e-06 27.2 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol3_chi PF04364.8 ETS87077.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC HeLo PF14479.1 ETS87078.1 - 2.9e-32 112.1 0.0 9.2e-31 107.2 0.0 2.4 1 1 1 2 2 2 2 Prion-inhibition and propagation DUF3632 PF12311.3 ETS87080.1 - 1.9e-05 24.5 0.4 4.3e-05 23.4 0.2 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3632) SURF4 PF02077.10 ETS87081.1 - 2.5e-96 322.1 6.4 2.9e-96 321.9 4.4 1.0 1 0 0 1 1 1 1 SURF4 family Tyrosinase PF00264.15 ETS87082.1 - 2.9e-32 112.6 4.5 4e-32 112.1 3.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BRO1 PF03097.13 ETS87083.1 - 1.2e-06 27.5 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.10 ETS87084.1 - 9.2e-129 430.2 26.7 4.4e-81 273.0 7.1 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family IBR PF01485.16 ETS87085.1 - 5e-07 29.4 22.5 1.2e-05 25.1 9.6 3.6 3 1 0 3 3 3 2 IBR domain FAA_hydrolase PF01557.13 ETS87086.1 - 1.6e-60 204.2 0.0 2.1e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Exo_endo_phos PF03372.18 ETS87087.1 - 2.6e-12 47.2 0.0 3.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 ETS87087.1 - 0.0001 21.8 0.0 0.00029 20.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase AAA_22 PF13401.1 ETS87088.1 - 0.00014 22.0 0.1 0.0064 16.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 ETS87088.1 - 0.00022 20.9 0.1 0.00098 18.8 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 ETS87088.1 - 0.0024 18.6 0.1 0.031 15.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS87088.1 - 0.0038 16.7 0.4 0.029 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 ETS87088.1 - 0.0056 16.9 0.4 0.04 14.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 ETS87088.1 - 0.0066 16.4 1.3 0.023 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 ETS87088.1 - 0.021 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 ETS87088.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 ETS87088.1 - 0.07 12.5 0.1 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 ETS87088.1 - 0.086 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 ETS87088.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 ETS87088.1 - 0.13 12.5 2.3 1.7 8.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NPV_P10 PF05531.7 ETS87088.1 - 0.18 12.0 2.9 27 5.0 0.9 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein KAP_NTPase PF07693.9 ETS87088.1 - 0.36 9.7 4.4 3.7 6.4 0.1 2.4 1 1 0 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.1 ETS87088.1 - 0.5 10.6 5.2 2 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain BOP1NT PF08145.7 ETS87089.1 - 4.8e-104 347.6 9.1 7.6e-104 347.0 6.3 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 ETS87089.1 - 7.7e-33 111.1 0.8 5.7e-12 45.0 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3312 PF11768.3 ETS87089.1 - 0.01 14.1 0.0 0.57 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 ETS87089.1 - 0.15 10.7 0.0 0.74 8.5 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 ETS87089.1 - 0.16 10.0 0.0 0.28 9.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lipase_GDSL_2 PF13472.1 ETS87090.1 - 5.3e-21 75.5 1.3 9.2e-21 74.7 0.6 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 ETS87090.1 - 1e-12 48.4 0.2 3.1e-12 46.8 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAM104 PF15434.1 ETS87091.1 - 4.9 7.3 5.8 0.99 9.6 1.0 1.9 2 0 0 2 2 2 0 Family 104 Prok-RING_1 PF14446.1 ETS87094.1 - 1.7 8.4 5.0 15 5.4 0.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 ETS87094.1 - 1.9 8.2 5.2 6.3 6.5 1.1 2.5 2 1 1 3 3 3 0 PHD-finger PP2C PF00481.16 ETS87095.1 - 1.2e-56 192.0 0.0 2.8e-56 190.7 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 ETS87095.1 - 1.9e-54 180.5 48.8 6.8e-08 31.9 0.3 12.4 7 5 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS87095.1 - 2.8e-40 135.8 53.0 1.2e-08 34.5 3.4 9.2 5 2 5 10 10 10 10 Leucine rich repeat Guanylate_cyc PF00211.15 ETS87095.1 - 8.2e-29 100.2 0.0 2.2e-28 98.8 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 ETS87095.1 - 2.1e-23 78.7 53.0 0.19 11.8 0.0 19.6 20 1 0 20 20 20 9 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 ETS87095.1 - 7e-19 66.9 1.1 1.8e-18 65.6 0.8 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 ETS87095.1 - 2.4e-12 44.9 51.2 0.64 10.4 0.1 16.8 16 2 2 18 18 17 2 Leucine rich repeat RA PF00788.18 ETS87095.1 - 2.6e-08 34.2 0.1 7.5e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 ETS87095.1 - 0.0018 18.1 53.9 6.6 7.1 0.0 15.4 17 2 2 19 19 17 2 Leucine Rich repeat LRR_5 PF13306.1 ETS87095.1 - 0.24 11.1 0.5 11 5.7 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) LRR_9 PF14580.1 ETS87095.1 - 0.32 10.5 12.8 2.9 7.3 0.1 4.1 2 1 2 4 4 4 0 Leucine-rich repeat RTC4 PF14474.1 ETS87096.1 - 1.2e-33 115.6 0.0 2.5e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 ETS87097.1 - 2.1e-33 115.7 13.2 1.6e-25 89.7 0.1 3.5 1 1 1 2 2 2 2 Dynamitin FH2 PF02181.18 ETS87097.1 - 0.00056 18.9 2.3 0.19 10.5 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Laminin_II PF06009.7 ETS87097.1 - 0.00061 19.5 9.7 0.13 11.9 0.2 4.2 2 1 2 4 4 4 2 Laminin Domain II Sipho_Gp157 PF05565.6 ETS87097.1 - 0.00076 19.0 7.6 0.1 12.1 0.0 3.2 3 0 0 3 3 3 2 Siphovirus Gp157 BLOC1_2 PF10046.4 ETS87097.1 - 0.002 18.2 8.7 0.38 10.9 0.1 3.8 2 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.8 ETS87097.1 - 0.0072 15.2 0.4 0.0072 15.2 0.3 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 Spore_III_AB PF09548.5 ETS87097.1 - 0.017 14.9 4.4 0.022 14.5 0.3 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PspA_IM30 PF04012.7 ETS87097.1 - 0.021 14.1 12.7 0.62 9.3 2.2 3.3 3 0 0 3 3 3 0 PspA/IM30 family YkyA PF10368.4 ETS87097.1 - 0.054 12.8 8.0 0.19 11.0 0.8 3.1 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Herpes_UL25 PF01499.11 ETS87097.1 - 0.063 11.5 7.9 0.095 10.9 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus UL25 family STAT_alpha PF01017.15 ETS87097.1 - 0.12 12.0 2.5 0.19 11.4 0.7 2.0 2 1 0 2 2 2 0 STAT protein, all-alpha domain V_ATPase_I PF01496.14 ETS87097.1 - 0.13 10.1 4.4 3.3 5.4 0.6 2.6 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.6 ETS87097.1 - 0.14 11.9 17.2 0.21 11.4 1.7 3.3 3 1 1 4 4 3 0 Protein of unknown function (DUF1192) DUF904 PF06005.7 ETS87097.1 - 0.18 12.0 8.2 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF948 PF06103.6 ETS87097.1 - 0.19 11.5 1.0 24 4.8 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 ETS87097.1 - 0.2 11.7 1.6 4.1 7.5 0.1 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 ETS87097.1 - 0.26 10.8 13.5 1.8 8.1 1.0 3.5 3 0 0 3 3 3 0 Septum formation initiator ATP-synt_E PF05680.7 ETS87097.1 - 0.27 11.2 0.1 0.27 11.2 0.0 2.7 3 0 0 3 3 2 0 ATP synthase E chain CENP-F_leu_zip PF10473.4 ETS87097.1 - 0.29 10.9 10.3 2.1 8.1 0.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.6 ETS87097.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Phage_int_SAM_2 PF12834.2 ETS87097.1 - 0.34 11.3 2.0 1.8 9.0 0.4 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal TPR_MLP1_2 PF07926.7 ETS87097.1 - 0.36 10.5 14.6 12 5.6 0.1 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 ETS87097.1 - 0.99 9.1 11.7 4.5 7.0 0.8 3.6 3 0 0 3 3 3 0 Prefoldin subunit DUF4201 PF13870.1 ETS87097.1 - 1.2 8.5 9.7 1.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Phasin PF05597.6 ETS87097.1 - 1.6 8.4 9.5 7.7 6.2 0.3 3.7 4 1 0 4 4 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Myosin_tail_1 PF01576.14 ETS87097.1 - 2.3 5.7 16.2 0.38 8.3 0.7 2.8 3 0 0 3 3 3 0 Myosin tail Spectrin PF00435.16 ETS87097.1 - 2.8 8.2 12.4 8.3 6.7 1.3 3.9 3 1 1 4 4 3 0 Spectrin repeat Phage_GP20 PF06810.6 ETS87097.1 - 3 7.2 11.6 0.17 11.3 0.6 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 GrpE PF01025.14 ETS87097.1 - 3.3 7.2 10.7 1.7 8.1 0.4 3.2 2 1 1 3 3 3 0 GrpE Spc24 PF08286.6 ETS87097.1 - 4.4 7.0 11.4 2.2 8.0 0.4 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 AAA_13 PF13166.1 ETS87097.1 - 5.2 5.4 10.6 68 1.7 7.5 2.3 1 1 1 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 ETS87097.1 - 5.3 6.8 18.0 1.1 9.0 0.9 3.4 4 0 0 4 4 3 0 Tropomyosin like Syntaxin-6_N PF09177.6 ETS87097.1 - 6.9 7.1 9.6 12 6.3 0.3 3.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF4140 PF13600.1 ETS87097.1 - 7.1 7.1 14.2 3 8.3 0.5 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF3449 PF11931.3 ETS87097.1 - 7.9 5.9 7.1 5.4 6.4 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) DUF4337 PF14235.1 ETS87097.1 - 8.1 6.2 11.1 4.3 7.1 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) VSP PF03302.8 ETS87098.1 - 0.033 12.8 0.1 0.033 12.8 0.1 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein Granulin PF00396.13 ETS87098.1 - 0.56 10.3 6.4 0.84 9.7 1.3 2.3 2 0 0 2 2 2 0 Granulin Ribosomal_S28e PF01200.13 ETS87099.1 - 3e-34 116.5 2.6 3.3e-34 116.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.15 ETS87100.1 - 1.5e-07 31.6 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family NACHT PF05729.7 ETS87101.1 - 5.2e-12 45.7 0.1 8e-07 28.8 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 ETS87101.1 - 7.7e-06 26.0 0.0 4.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS87101.1 - 0.0001 22.3 0.3 0.0015 18.5 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 ETS87101.1 - 0.0015 18.8 0.0 0.0056 16.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 ETS87101.1 - 0.0022 18.1 0.0 0.0078 16.3 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 ETS87101.1 - 0.005 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 ETS87101.1 - 0.041 14.6 0.0 0.35 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 ETS87101.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS87101.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 ETS87101.1 - 0.094 12.1 0.6 0.49 9.7 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 ETS87101.1 - 0.095 13.0 0.0 0.53 10.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain Aldolase_II PF00596.16 ETS87102.1 - 7.7e-48 162.5 0.1 9.3e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.13 ETS87103.1 - 2.5e-22 79.0 0.3 3.9e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87103.1 - 1.4e-09 37.6 8.9 3.5e-09 36.4 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 ETS87104.1 - 4.4e-24 85.0 0.1 5.9e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS87104.1 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain FAD_binding_3 PF01494.14 ETS87105.1 - 1.8e-11 43.6 0.0 2e-09 37.0 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 ETS87105.1 - 0.0009 19.3 0.0 0.0022 18.0 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS87105.1 - 0.072 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS87105.1 - 0.086 11.7 0.2 0.78 8.5 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase NmrA PF05368.8 ETS87106.1 - 3.6e-27 95.1 0.0 4.3e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 ETS87106.1 - 0.00077 19.7 0.0 0.0025 18.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 ETS87106.1 - 0.00081 19.4 0.2 0.0015 18.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS87106.1 - 0.00095 18.6 0.0 0.0063 15.9 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 ETS87106.1 - 0.0062 15.2 0.3 0.0095 14.6 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribul_P_3_epim PF00834.14 ETS87106.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family LigB PF02900.13 ETS87107.1 - 1.4e-47 161.9 0.0 1.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 ETS87108.1 - 1.4e-10 40.4 0.6 2.2e-10 39.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87108.1 - 3.2e-08 33.3 9.1 6.7e-08 32.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 ETS87109.1 - 1.3e-36 125.3 0.0 2.4e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS87109.1 - 1.9e-23 82.3 0.0 2.3e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 ETS87109.1 - 0.0002 21.6 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 2 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 ETS87109.1 - 0.0066 16.0 1.1 0.57 9.7 0.3 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain OCD_Mu_crystall PF02423.10 ETS87109.1 - 0.034 12.9 0.1 0.049 12.3 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Clr5 PF14420.1 ETS87110.1 - 1.2e-08 34.7 0.3 3.4e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 Clr5 domain Uso1_p115_head PF04869.9 ETS87110.1 - 0.0032 16.2 0.1 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Flavodoxin_1 PF00258.20 ETS87111.1 - 1e-11 45.0 0.4 2.8e-11 43.5 0.3 2.0 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 ETS87111.1 - 5.9e-10 38.8 0.0 7.6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 ETS87111.1 - 3.8e-06 26.5 0.0 4.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 ETS87111.1 - 0.0015 18.5 0.0 0.042 13.8 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 ETS87111.1 - 0.0035 16.6 0.1 0.036 13.4 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin MORN PF02493.15 ETS87111.1 - 0.0084 15.7 3.9 0.82 9.5 0.4 2.5 2 0 0 2 2 2 2 MORN repeat DUF4575 PF15143.1 ETS87112.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) AT_hook PF02178.14 ETS87112.1 - 0.1 12.3 7.7 0.33 10.7 5.3 1.9 1 0 0 1 1 1 0 AT hook motif DNA_pol3_theta PF06440.6 ETS87113.1 - 0.14 11.7 0.4 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, theta subunit GFA PF04828.9 ETS87114.1 - 1.5e-09 37.6 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 ETS87114.1 - 0.0023 17.3 0.1 0.0023 17.3 0.1 2.4 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.8 ETS87114.1 - 0.33 10.5 3.8 0.89 9.1 1.0 2.3 2 0 0 2 2 2 0 CSL zinc finger Ribosomal_L37e PF01907.14 ETS87114.1 - 0.38 10.5 8.9 5 7.0 0.1 3.3 2 1 1 3 3 3 0 Ribosomal protein L37e p450 PF00067.17 ETS87115.1 - 2.6e-26 92.1 0.0 6e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 SpvB PF03534.8 ETS87117.1 - 1.1e-74 251.1 0.0 2.1e-74 250.2 0.0 1.5 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 ETS87117.1 - 5.7e-35 120.3 15.1 2.8e-31 108.2 0.1 6.8 5 2 2 8 8 8 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 ETS87117.1 - 3.1e-23 82.0 0.4 6.9e-23 80.9 0.3 1.6 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.1 ETS87117.1 - 0.0043 17.3 0.4 0.0043 17.3 0.3 5.5 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 ETS87117.1 - 0.097 12.3 12.0 1 9.1 0.0 4.6 4 0 0 4 4 4 0 FG-GAP repeat ISG65-75 PF11727.3 ETS87118.1 - 3.2 6.7 8.2 0.27 10.2 0.5 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein adh_short PF00106.20 ETS87120.1 - 8.5e-13 48.5 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87120.1 - 0.00019 21.3 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87120.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.14 ETS87120.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipase_GDSL PF00657.17 ETS87122.1 - 6.8e-10 39.1 1.9 9.1e-10 38.7 1.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HET PF06985.6 ETS87123.1 - 1.4e-16 60.9 0.2 3.2e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 ETS87124.1 - 0.0028 18.1 0.5 0.44 11.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 ETS87124.1 - 0.011 16.0 0.2 0.071 13.4 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) p450 PF00067.17 ETS87125.1 - 3.1e-47 161.1 0.0 4.5e-47 160.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3632 PF12311.3 ETS87126.1 - 2e-19 70.1 0.6 3.2e-19 69.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Amidase PF01425.16 ETS87127.1 - 6.7e-33 114.1 0.3 1.7e-32 112.8 0.1 1.6 2 0 0 2 2 2 1 Amidase Cas_Cas6 PF01881.11 ETS87128.1 - 0.039 14.1 0.5 0.076 13.2 0.3 1.4 1 1 0 1 1 1 0 CRISPR associated protein Cas6 DnaB_2 PF07261.6 ETS87128.1 - 0.099 12.2 0.6 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment Arginase PF00491.16 ETS87129.1 - 1.7e-87 293.2 0.0 2e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Sugar_tr PF00083.19 ETS87130.1 - 9.6e-103 344.1 31.2 1.1e-102 343.9 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS87130.1 - 5.8e-33 114.0 31.2 5.8e-33 114.0 21.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 ETS87131.1 - 6.4e-106 346.9 6.6 7e-18 64.7 0.0 5.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87131.1 - 2.1e-73 238.6 18.0 4.7e-07 29.2 0.0 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 ETS87131.1 - 5.9e-52 173.1 2.0 2.8e-09 37.2 0.0 8.9 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS87131.1 - 2.6e-51 170.5 9.8 8.4e-09 35.3 0.0 10.5 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS87131.1 - 1.2e-44 145.7 0.8 8.2e-05 22.4 0.0 11.5 11 0 0 11 11 11 7 Ankyrin repeat NACHT PF05729.7 ETS87131.1 - 7e-08 32.3 0.2 5.9e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS87131.1 - 4.8e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 ETS87131.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 ETS87131.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 ETS87131.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 ETS87131.1 - 0.027 13.3 0.0 0.092 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 ETS87131.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 ETS87131.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 ETS87131.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PIF1 PF05970.9 ETS87131.1 - 0.21 10.4 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RVP PF00077.15 ETS87131.1 - 0.85 9.5 5.9 73 3.3 0.0 4.5 3 2 2 5 5 4 0 Retroviral aspartyl protease HET PF06985.6 ETS87132.1 - 1e-18 67.8 13.6 2.7e-17 63.2 2.2 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 ETS87133.1 - 1.7e-22 80.0 5.3 3.4e-20 72.6 3.7 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 ETS87133.1 - 7.4e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87133.1 - 0.00012 21.7 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 ETS87133.1 - 0.00019 21.5 0.0 0.041 14.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS87133.1 - 0.00028 20.8 0.0 0.014 15.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 ETS87133.1 - 0.00059 20.2 0.0 0.016 15.7 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) APH PF01636.18 ETS87134.1 - 8.1e-13 48.6 0.0 3.1e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 ETS87134.1 - 6.4e-07 29.1 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 ETS87134.1 - 0.021 13.8 0.0 0.062 12.2 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 ETS87134.1 - 0.034 12.7 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 ETS87134.1 - 0.044 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF2119 PF09892.4 ETS87134.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) DAO PF01266.19 ETS87135.1 - 3.1e-35 121.7 0.0 4.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS87135.1 - 2.7e-07 30.5 0.0 7.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS87135.1 - 0.0005 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS87135.1 - 0.0028 18.0 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 ETS87135.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 ETS87135.1 - 0.0088 15.1 0.0 0.019 14.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 ETS87135.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 ETS87135.1 - 0.018 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 ETS87135.1 - 0.039 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 ETS87135.1 - 0.054 13.4 0.0 0.3 11.1 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_2 PF03446.10 ETS87135.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 ETS87135.1 - 0.1 12.6 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS87135.1 - 0.14 10.6 0.2 0.57 8.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Amidase PF01425.16 ETS87136.1 - 5.9e-34 117.6 0.3 9.4e-34 117.0 0.2 1.2 1 0 0 1 1 1 1 Amidase Amino_oxidase PF01593.19 ETS87137.1 - 5.1e-29 101.6 0.6 4.5e-18 65.5 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS87137.1 - 4.9e-08 32.8 0.0 1.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 ETS87137.1 - 0.002 18.1 0.1 0.008 16.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 ETS87137.1 - 0.0085 15.0 0.2 0.014 14.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 ETS87137.1 - 0.012 14.6 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 ETS87137.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 ETS87138.1 - 2e-44 151.7 47.6 7.1e-42 143.3 32.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS87138.1 - 2.3e-14 52.8 10.9 2.3e-14 52.8 7.6 3.7 3 1 1 4 4 4 3 Sugar (and other) transporter PALP PF00291.20 ETS87139.1 - 2.1e-28 99.4 0.0 4.4e-28 98.3 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 ETS87139.1 - 7.5e-07 29.4 0.0 2.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain 2-Hacid_dh_C PF02826.14 ETS87140.1 - 2.1e-44 150.8 0.1 3.8e-44 149.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS87140.1 - 9.5e-21 73.6 0.0 1.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 ETS87140.1 - 0.0029 17.4 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 ETS87140.1 - 0.0035 16.7 0.1 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 ETS87140.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 ETS87140.1 - 0.046 13.0 0.4 0.12 11.7 0.2 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 ETS87140.1 - 0.054 13.3 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 ETS87141.1 - 8.7e-18 64.1 28.1 6.4e-16 58.0 20.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 ETS87141.1 - 1.4 7.8 4.4 0.21 10.5 0.3 1.8 2 0 0 2 2 2 0 Peptidase family M50 Ank_2 PF12796.2 ETS87142.1 - 5.9e-54 180.3 13.5 7.8e-18 64.5 0.3 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87142.1 - 7.8e-40 132.7 11.9 4.2e-08 32.5 0.3 8.4 8 0 0 8 8 8 7 Ankyrin repeat HET PF06985.6 ETS87142.1 - 3.7e-37 127.5 1.2 3.7e-37 127.5 0.9 2.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.1 ETS87142.1 - 4.1e-33 110.1 0.8 9.5e-06 25.3 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 ETS87142.1 - 9.4e-27 92.9 3.9 2.5e-08 34.2 0.1 7.5 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS87142.1 - 9.8e-27 92.3 6.0 9.2e-08 32.0 0.2 7.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Nop14 PF04147.7 ETS87142.1 - 0.71 7.7 7.6 1 7.1 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 ETS87142.1 - 4 5.3 12.7 5.9 4.7 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 ETS87142.1 - 4.8 6.2 15.7 8 5.4 10.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glyco_hydro_43 PF04616.9 ETS87143.1 - 9.1e-68 228.4 3.4 1.4e-67 227.8 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Stress-antifung PF01657.12 ETS87143.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Salt stress response/antifungal Abhydrolase_6 PF12697.2 ETS87144.1 - 2.2e-18 67.0 0.0 2.6e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87144.1 - 4.7e-06 26.4 0.0 6.2e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family REF PF05755.7 ETS87144.1 - 0.009 15.7 0.4 0.62 9.7 0.1 2.2 2 0 0 2 2 2 2 Rubber elongation factor protein (REF) Acyl-CoA_dh_N PF02771.11 ETS87144.1 - 0.085 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Mob1_phocein PF03637.12 ETS87145.1 - 1.3e-37 129.1 2.6 8.3e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 ETS87146.1 - 2.7e-28 98.8 0.1 2.7e-28 98.8 0.1 1.8 2 0 0 2 2 2 1 Leo1-like protein DUF3716 PF12511.3 ETS87147.1 - 1.3e-10 40.6 7.9 2.3e-10 39.9 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3840 PF12944.2 ETS87147.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Vfa1 PF08432.5 ETS87147.1 - 1.1 9.2 7.1 3.7 7.5 4.9 1.9 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 ETS87147.1 - 7.5 5.6 9.2 11 5.0 6.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3336 PF11815.3 ETS87148.1 - 1.9e-34 118.2 1.6 5.2e-34 116.8 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 ETS87148.1 - 1.2e-13 51.5 1.0 4.5e-13 49.6 0.7 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF336 PF03928.9 ETS87149.1 - 0.062 13.1 0.0 0.096 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF336) DUF4360 PF14273.1 ETS87150.1 - 0.044 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) IBR PF01485.16 ETS87150.1 - 5.3 6.9 6.7 1.4 8.8 0.1 2.3 2 1 0 2 2 2 0 IBR domain zf-H2C2_2 PF13465.1 ETS87152.1 - 2.5e-14 52.7 8.4 5.1e-08 32.8 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETS87152.1 - 1.7e-12 46.8 11.1 7.8e-06 25.9 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS87152.1 - 2.2e-11 43.2 11.2 3.7e-05 23.7 1.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 ETS87152.1 - 0.00073 19.6 7.7 0.013 15.6 0.2 4.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS87152.1 - 0.001 19.1 16.1 0.029 14.5 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 ETS87152.1 - 0.2 11.9 0.4 0.46 10.7 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 ETS87152.1 - 0.55 10.3 3.4 4.7 7.3 2.4 2.2 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 ETS87152.1 - 5.1 7.1 11.8 11 6.1 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger AOX PF01786.12 ETS87153.1 - 2.3e-83 278.6 0.2 2.8e-83 278.4 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase eIF3_subunit PF08597.5 ETS87154.1 - 1.3e-67 227.8 28.2 1.5e-67 227.7 19.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.6 ETS87154.1 - 0.19 10.9 3.8 0.38 10.0 2.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Vpu PF00558.14 ETS87154.1 - 0.63 9.6 5.2 1.6 8.3 3.6 1.7 1 0 0 1 1 1 0 Vpu protein PAN_4 PF14295.1 ETS87155.1 - 0.00059 19.4 5.4 0.013 15.1 0.5 3.0 2 0 0 2 2 2 2 PAN domain MDM31_MDM32 PF08118.6 ETS87156.1 - 1.6e-178 594.2 0.5 5.7e-177 589.1 0.0 2.5 2 1 0 2 2 2 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2360 PF10152.4 ETS87156.1 - 0.018 15.3 5.8 0.099 12.9 0.4 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_60s PF00428.14 ETS87156.1 - 0.033 14.5 10.9 0.23 11.8 0.1 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 ETS87156.1 - 0.75 10.3 0.0 0.75 10.3 0.0 3.2 3 1 0 3 3 3 0 Chorion family 2 KH_1 PF00013.24 ETS87157.1 - 2.3e-05 23.9 2.2 5.1e-05 22.8 1.6 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 ETS87157.1 - 0.056 13.1 0.6 0.14 11.8 0.4 1.7 1 0 0 1 1 1 0 KH domain Rad60-SLD PF11976.3 ETS87158.1 - 5.7e-15 54.7 0.6 7.1e-14 51.2 0.2 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETS87158.1 - 0.044 13.1 0.1 0.14 11.5 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin family Atg8 PF02991.11 ETS87158.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like LSM PF01423.17 ETS87159.1 - 3.8e-19 68.0 0.1 4.8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 ETS87159.1 - 0.00064 19.5 0.1 0.00085 19.1 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain IceA2 PF05862.6 ETS87159.1 - 0.087 12.5 0.9 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Methyltransf_11 PF08241.7 ETS87160.1 - 1.4e-12 47.9 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS87160.1 - 3.5e-07 30.0 0.0 5.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87160.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87160.1 - 1.8e-05 25.3 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS87160.1 - 5.4e-05 22.4 0.0 8.3e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 ETS87160.1 - 0.00025 21.4 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS87160.1 - 0.00028 20.8 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87160.1 - 0.00053 20.2 0.0 0.00097 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS87160.1 - 0.018 14.1 0.0 0.71 8.8 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 ETS87160.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CAP59_mtransfer PF11735.3 ETS87161.1 - 9.4e-74 247.6 0.0 1.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tim17 PF02466.14 ETS87162.1 - 1.6e-26 92.8 0.7 2.2e-26 92.4 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Abhydrolase_3 PF07859.8 ETS87164.1 - 7.3e-30 104.1 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS87164.1 - 2e-06 26.8 0.0 3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS87164.1 - 0.0078 15.9 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 ETS87165.1 - 8.2e-07 27.9 0.1 1.1e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3253 PF11625.3 ETS87166.1 - 1.9e-23 82.1 0.1 2.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) DUF2766 PF10964.3 ETS87166.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) zf-RING_2 PF13639.1 ETS87167.1 - 9e-10 38.2 8.1 9e-10 38.2 5.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 ETS87167.1 - 8.2e-08 31.7 7.9 8.2e-08 31.7 5.5 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS87167.1 - 1.5e-06 27.8 5.8 1.5e-06 27.8 4.0 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS87167.1 - 7.5e-06 25.8 8.4 7.5e-06 25.8 5.8 2.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 ETS87167.1 - 2.6e-05 24.2 8.4 2.6e-05 24.2 5.8 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 ETS87167.1 - 5.8e-05 22.8 3.6 5.8e-05 22.8 2.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 ETS87167.1 - 0.0028 17.3 2.2 0.0063 16.2 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_3 PF14369.1 ETS87167.1 - 0.0066 16.4 3.5 0.02 14.8 2.4 1.8 1 0 0 1 1 1 1 zinc-finger SMN PF06003.7 ETS87167.1 - 0.053 12.6 0.5 0.097 11.7 0.3 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-Nse PF11789.3 ETS87167.1 - 0.18 11.3 10.3 0.063 12.8 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit YABBY PF04690.8 ETS87167.1 - 0.19 11.9 2.4 0.28 11.4 1.7 1.3 1 0 0 1 1 1 0 YABBY protein zf-Apc11 PF12861.2 ETS87167.1 - 0.46 10.3 13.3 0.029 14.2 5.3 1.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETS87167.1 - 2.4 7.7 16.9 0.03 13.9 4.4 2.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 ETS87167.1 - 3.2 7.6 7.2 9 6.1 4.5 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.7 ETS87167.1 - 9.2 6.1 16.5 0.43 10.3 2.3 3.0 1 1 0 2 2 2 0 zinc-ribbons zf-MYND PF01753.13 ETS87169.1 - 4.1e-10 39.3 16.3 6.6e-10 38.7 11.3 1.3 1 0 0 1 1 1 1 MYND finger Siva PF05458.7 ETS87169.1 - 0.78 9.2 10.8 1.2 8.6 7.5 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3844 PF12955.2 ETS87169.1 - 0.89 9.6 8.1 1.4 9.0 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) HET PF06985.6 ETS87170.1 - 3.9e-19 69.1 0.1 1.4e-18 67.4 0.1 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EGF_2 PF07974.8 ETS87171.1 - 0.00023 21.2 7.7 0.00044 20.3 5.3 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 ETS87171.1 - 0.0039 17.1 5.2 0.012 15.6 3.6 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF EB PF01683.13 ETS87171.1 - 0.065 13.3 1.5 0.13 12.3 1.0 1.4 1 0 0 1 1 1 0 EB module Sugar_tr PF00083.19 ETS87172.1 - 2.6e-97 326.2 29.1 2.9e-97 326.0 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS87172.1 - 2.1e-28 99.0 31.4 5.2e-21 74.7 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS87172.1 - 0.00025 19.5 34.7 0.011 14.1 5.3 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein FAD_binding_4 PF01565.18 ETS87173.1 - 4.1e-22 78.1 1.5 6.2e-22 77.5 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.2 ETS87174.1 - 9.7e-17 61.6 0.2 1.7e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87174.1 - 7.2e-07 29.0 0.0 1.2e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS87174.1 - 1.3e-05 24.9 0.5 5.7e-05 22.8 0.3 2.0 1 1 0 1 1 1 1 Putative lysophospholipase 7TMR-DISM_7TM PF07695.6 ETS87175.1 - 0.008 15.8 10.4 0.008 15.8 7.2 1.7 2 0 0 2 2 2 1 7TM diverse intracellular signalling DUF4083 PF13314.1 ETS87175.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) WBS_methylT PF12589.3 ETS87177.1 - 3.3e-17 62.7 4.6 6.3e-17 61.8 3.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 ETS87177.1 - 5.9e-11 42.7 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87177.1 - 3.6e-07 30.4 0.0 9.2e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87177.1 - 4.1e-06 26.4 0.0 6.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87177.1 - 0.0002 21.7 0.0 0.00092 19.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87177.1 - 0.0007 20.1 0.0 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS87177.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS87177.1 - 0.0025 17.4 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 ETS87177.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 ETS87177.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Erv26 PF04148.8 ETS87178.1 - 5.7e-85 283.9 5.5 6.6e-85 283.7 3.8 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 ABC_tran PF00005.22 ETS87179.1 - 6.3e-55 185.2 0.1 1.4e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 ETS87179.1 - 6.1e-22 78.1 50.6 1.8e-19 69.9 16.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 ETS87179.1 - 1.4e-21 77.7 0.0 7.2e-06 26.1 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 ETS87179.1 - 3.3e-09 36.2 0.1 0.21 10.7 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 ETS87179.1 - 1.8e-06 28.4 0.8 0.012 15.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 ETS87179.1 - 1.8e-05 24.8 0.7 0.09 12.7 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS87179.1 - 2e-05 24.7 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 ETS87179.1 - 9.2e-05 21.3 0.0 0.035 12.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 ETS87179.1 - 0.00013 21.4 7.6 0.0079 15.6 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 ETS87179.1 - 0.0002 20.8 0.1 0.55 9.6 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 ETS87179.1 - 0.00022 20.3 0.3 0.38 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 ETS87179.1 - 0.00045 19.9 2.4 0.56 9.9 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 ETS87179.1 - 0.00064 19.3 0.9 0.33 10.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 ETS87179.1 - 0.00082 18.3 0.6 2 7.2 0.1 4.1 3 1 0 3 3 3 1 NB-ARC domain DUF258 PF03193.11 ETS87179.1 - 0.0015 17.7 0.8 0.14 11.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 ETS87179.1 - 0.0057 16.8 0.3 3.8 7.7 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 ETS87179.1 - 0.018 14.6 0.4 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 ETS87179.1 - 0.025 14.2 0.3 1.8 8.2 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_PrkA PF08298.6 ETS87179.1 - 0.029 13.0 0.1 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_14 PF13173.1 ETS87179.1 - 0.031 14.1 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 ETS87179.1 - 0.037 13.9 0.0 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 ETS87179.1 - 0.038 13.4 0.7 33 3.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 ETS87179.1 - 0.039 13.4 0.9 5.8 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 ETS87179.1 - 0.046 12.6 0.8 1.6 7.5 0.1 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein MutS_V PF00488.16 ETS87179.1 - 0.046 13.1 0.1 30 3.9 0.0 3.2 3 0 0 3 3 3 0 MutS domain V AAA_15 PF13175.1 ETS87179.1 - 0.054 12.5 0.0 17 4.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 ETS87179.1 - 0.055 12.8 0.2 11 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS87179.1 - 0.06 13.0 0.2 6.3 6.4 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 ETS87179.1 - 0.099 12.2 0.2 6.5 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 ETS87179.1 - 0.13 12.1 0.3 13 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 ETS87179.1 - 0.38 9.3 0.1 1.5 7.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.1 ETS87179.1 - 4.6 5.5 2.3 20 3.4 0.1 2.3 3 0 0 3 3 3 0 AAA domain Aldedh PF00171.17 ETS87180.1 - 2.8e-152 507.2 0.0 3.1e-152 507.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS87180.1 - 2.2e-05 23.3 0.0 3.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 ETS87180.1 - 0.021 14.0 0.1 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GMC_oxred_N PF00732.14 ETS87181.1 - 7.1e-61 205.9 0.0 8.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS87181.1 - 7e-39 133.3 0.6 8.4e-38 129.9 0.0 2.4 3 0 0 3 3 3 1 GMC oxidoreductase DAO PF01266.19 ETS87181.1 - 3.4e-07 29.4 0.1 0.00036 19.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS87181.1 - 4.3e-05 23.4 0.2 0.00011 22.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS87181.1 - 0.00039 19.4 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 ETS87181.1 - 0.0013 17.6 1.7 0.36 9.6 0.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 ETS87181.1 - 0.029 12.8 0.5 0.11 10.9 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 ETS87181.1 - 0.065 12.0 3.6 0.2 10.4 1.7 2.2 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 ETS87181.1 - 0.11 12.4 0.2 0.54 10.1 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS87181.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 ETS87181.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 ETS87181.1 - 0.31 11.4 2.2 0.55 10.6 0.3 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 ETS87182.1 - 7.1e-08 32.2 13.7 1.2e-07 31.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 ETS87183.1 - 1.4e-05 24.8 4.2 4.8e-05 23.0 2.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 ETS87183.1 - 0.00025 20.6 0.1 0.00057 19.4 0.0 1.6 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 ETS87184.1 - 5.8e-22 77.8 0.1 8.3e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87184.1 - 7.5e-10 38.5 7.8 1.3e-09 37.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T2SJ PF11612.3 ETS87184.1 - 0.0081 15.9 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J FAD_binding_3 PF01494.14 ETS87185.1 - 4.5e-25 88.4 0.2 3.6e-24 85.4 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS87185.1 - 5.1e-05 23.2 2.6 0.00014 21.8 1.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 ETS87185.1 - 0.00012 21.0 4.5 0.00044 19.2 2.4 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS87185.1 - 0.00093 18.1 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 ETS87185.1 - 0.0021 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 ETS87185.1 - 0.0026 17.6 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS87185.1 - 0.0058 15.7 0.0 0.0093 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETS87185.1 - 0.0062 16.9 3.3 0.011 16.0 1.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 ETS87185.1 - 0.012 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 ETS87185.1 - 0.012 14.1 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 ETS87185.1 - 0.019 14.7 1.6 0.64 9.7 0.6 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS87185.1 - 0.064 13.3 1.9 0.18 11.8 0.6 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS87185.1 - 0.067 12.2 0.9 3.8 6.4 0.2 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Asp_Glu_race PF01177.17 ETS87186.1 - 3.9e-18 66.1 0.2 4.6e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase MFS_1 PF07690.11 ETS87187.1 - 2.5e-21 75.8 40.2 2e-20 72.8 27.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 ETS87188.1 - 0.092 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger MutS_V PF00488.16 ETS87189.1 - 1.8e-78 263.2 0.0 3.4e-78 262.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS87189.1 - 7.6e-37 127.0 2.8 1.5e-36 126.1 1.9 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 ETS87189.1 - 2.1e-27 95.4 0.0 4.4e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 ETS87189.1 - 5.5e-09 36.2 0.1 2.7e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 ETS87189.1 - 2.6e-06 27.5 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV Glyco_hydro_11 PF00457.12 ETS87190.1 - 3e-78 261.3 22.0 3.5e-78 261.1 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_S8 PF00082.17 ETS87191.1 - 2.5e-42 144.9 10.2 3.5e-42 144.4 7.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 ETS87191.1 - 4.2e-06 27.2 0.0 7.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2668 PF10873.3 ETS87192.1 - 4.2e-05 23.7 1.9 9e-05 22.6 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF3481 PF11980.3 ETS87192.1 - 0.02 14.7 0.0 0.077 12.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Glycophorin_A PF01102.13 ETS87192.1 - 0.1 12.3 9.9 0.066 12.9 3.2 2.7 3 0 0 3 3 3 0 Glycophorin A MGC-24 PF05283.6 ETS87192.1 - 1.8 8.3 19.5 0.28 10.9 0.5 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Tannase PF07519.6 ETS87193.1 - 1.3e-90 304.3 5.5 5.2e-90 302.4 3.8 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 ETS87193.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAF1_ABF1 PF04684.8 ETS87194.1 - 2.7 6.7 5.5 3.3 6.4 3.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF221 PF02714.10 ETS87195.1 - 1.1e-92 310.3 18.7 1.6e-92 309.8 13.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS87195.1 - 8.2e-41 139.1 1.3 8.2e-41 139.1 0.9 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 ETS87195.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 ETS87195.1 - 0.00025 19.8 1.0 0.00025 19.8 0.7 1.7 2 0 0 2 2 2 1 Calcium-activated chloride channel RRM_6 PF14259.1 ETS87195.1 - 0.041 13.8 0.0 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1910 PF08928.5 ETS87195.1 - 0.18 11.8 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) O-FucT PF10250.4 ETS87196.1 - 2.3e-11 43.3 0.0 6.3e-09 35.3 0.0 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cupin_2 PF07883.6 ETS87198.1 - 0.00011 21.6 0.1 0.00018 20.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Zn_clus PF00172.13 ETS87199.1 - 3.8e-07 29.9 6.0 6.2e-07 29.2 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAK_assoc PF14380.1 ETS87199.1 - 0.15 12.6 4.6 0.12 12.9 1.8 1.9 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal WD40 PF00400.27 ETS87200.1 - 4.2e-79 257.8 26.2 8.9e-16 57.0 0.4 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 ETS87200.1 - 2.8e-07 29.0 6.4 0.023 12.8 0.0 4.6 3 2 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETS87200.1 - 5.6e-07 29.4 0.7 0.0024 17.5 0.0 3.5 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 ETS87200.1 - 0.00063 19.2 6.9 0.00083 18.8 0.1 2.7 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 ETS87200.1 - 0.001 18.6 1.6 2 8.1 0.0 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat NLE PF08154.7 ETS87200.1 - 0.0044 17.0 0.1 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 ETS87200.1 - 0.021 14.7 0.1 1.6 8.7 0.0 2.8 2 1 1 3 3 3 0 Siderophore-interacting FAD-binding domain Nbas_N PF15492.1 ETS87200.1 - 0.025 13.6 0.3 7.2 5.6 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 ETS87200.1 - 0.23 10.8 1.0 15 4.9 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature MutS_V PF00488.16 ETS87201.1 - 3.6e-73 245.8 0.1 5.9e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS87201.1 - 4.5e-24 85.3 0.1 3.4e-23 82.4 0.0 2.4 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 ETS87201.1 - 7.9e-08 32.4 0.3 2.5e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 ETS87201.1 - 7e-07 29.3 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Glyco_transf_20 PF00982.16 ETS87202.1 - 1.6e-161 537.9 0.1 2.1e-161 537.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 ETS87202.1 - 5.5e-42 143.2 0.0 9.3e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 ETS87202.1 - 0.00052 19.6 0.0 0.0065 16.0 0.0 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.14 ETS87203.1 - 6.3e-80 268.8 0.0 8.2e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS87203.1 - 2.5e-06 26.6 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS87203.1 - 1.9e-05 24.6 0.0 9.1e-05 22.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS87203.1 - 0.0001 21.3 0.0 0.064 12.1 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS87203.1 - 0.00035 20.6 0.2 0.0016 18.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS87203.1 - 0.0026 18.1 0.1 0.87 10.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS87203.1 - 0.016 14.0 0.0 0.92 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 ETS87203.1 - 0.021 14.5 0.2 0.11 12.2 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 ETS87203.1 - 0.028 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Optomotor-blind PF11078.3 ETS87203.1 - 0.055 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region FAD_oxidored PF12831.2 ETS87203.1 - 0.1 11.6 1.6 0.93 8.4 1.1 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase HET PF06985.6 ETS87204.1 - 1e-19 71.0 0.1 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 ETS87205.1 - 6.2e-21 74.7 0.0 8.2e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87205.1 - 4.8e-10 38.9 0.0 6.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 ETS87205.1 - 0.065 12.0 0.0 0.25 10.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase TMF_TATA_bd PF12325.3 ETS87206.1 - 0.88 9.3 4.5 9.7 5.9 1.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding M-factor PF03855.8 ETS87206.1 - 4.1 7.4 10.1 4.2 7.4 3.2 2.5 2 0 0 2 2 2 0 M-factor Peptidase_S8 PF00082.17 ETS87207.1 - 1.9e-30 105.9 0.0 3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family CorA PF01544.13 ETS87209.1 - 5e-05 22.4 12.6 0.0036 16.3 8.7 2.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein APG6 PF04111.7 ETS87209.1 - 0.0023 17.0 3.6 0.0033 16.5 2.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4200 PF13863.1 ETS87209.1 - 0.0062 16.4 9.0 0.01 15.7 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) 60KD_IMP PF02096.15 ETS87209.1 - 0.075 12.6 7.0 1.2 8.7 2.5 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein YwiC PF14256.1 ETS87209.1 - 0.091 12.8 1.0 0.17 11.9 0.7 1.4 1 0 0 1 1 1 0 YwiC-like protein DUF342 PF03961.8 ETS87209.1 - 0.19 10.1 3.8 0.27 9.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sugarporin_N PF11471.3 ETS87209.1 - 3.6 7.2 10.1 7.8 6.2 7.0 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension IncA PF04156.9 ETS87209.1 - 5.4 6.5 6.4 9.3 5.7 4.5 1.4 1 0 0 1 1 1 0 IncA protein HTH_Tnp_Tc5 PF03221.11 ETS87210.1 - 5.8e-08 32.4 0.2 4.1e-07 29.7 0.4 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ABC_tran PF00005.22 ETS87211.1 - 4.2e-43 146.9 0.3 3.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS87211.1 - 1.6e-36 126.1 26.1 8.4e-24 84.4 5.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 ETS87211.1 - 2.5e-12 47.3 0.6 0.021 14.7 0.0 4.4 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 ETS87211.1 - 3.5e-10 39.4 4.0 0.00024 20.3 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 ETS87211.1 - 2.5e-07 30.1 1.9 0.015 14.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS87211.1 - 5.6e-07 29.7 0.7 0.00078 19.4 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 ETS87211.1 - 2.8e-05 24.2 0.4 0.047 13.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 ETS87211.1 - 7.6e-05 23.1 1.4 0.014 15.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 ETS87211.1 - 0.00027 19.9 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 ETS87211.1 - 0.00041 20.2 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 ETS87211.1 - 0.00091 19.1 0.3 1.8 8.5 0.0 3.0 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 ETS87211.1 - 0.00091 19.7 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 ETS87211.1 - 0.0023 18.2 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS87211.1 - 0.0088 15.4 0.6 3.8 6.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 ETS87211.1 - 0.017 14.8 1.8 0.25 11.1 0.2 3.2 3 0 0 3 3 3 0 Part of AAA domain Zeta_toxin PF06414.7 ETS87211.1 - 0.023 13.7 0.1 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 ETS87211.1 - 0.027 13.6 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 ETS87211.1 - 0.027 15.2 4.5 5 7.9 0.1 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 ETS87211.1 - 0.028 14.1 0.1 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 ETS87211.1 - 0.032 14.1 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 ETS87211.1 - 0.037 13.9 0.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 ETS87211.1 - 0.068 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 ETS87211.1 - 0.11 12.2 2.3 10 5.7 0.5 2.6 2 0 0 2 2 2 0 NTPase MobB PF03205.9 ETS87211.1 - 0.11 12.2 0.7 9 5.9 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 ETS87211.1 - 0.11 11.9 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 ETS87211.1 - 0.15 12.2 0.7 29 4.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS87211.1 - 0.16 11.3 4.8 13 5.1 0.1 3.2 2 1 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 ETS87211.1 - 0.2 11.4 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 ETS87211.1 - 4.3 6.7 4.7 1.5 8.1 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 ETS87212.1 - 0 1991.3 0.0 1.7e-87 293.5 0.0 7.5 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.15 ETS87212.1 - 0 1489.6 7.8 3.4e-51 173.8 0.0 11.6 11 0 0 11 11 11 11 Condensation domain PP-binding PF00550.20 ETS87212.1 - 3.1e-77 254.7 17.7 8.2e-14 51.6 0.0 9.1 9 0 0 9 9 9 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 ETS87212.1 - 2.5e-45 153.2 3.5 5.6e-07 30.4 0.0 8.2 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain Transferase PF02458.10 ETS87212.1 - 2e-08 33.0 0.0 0.33 9.3 0.0 5.6 7 0 0 7 7 7 4 Transferase family AATase PF07247.7 ETS87212.1 - 0.0001 21.0 0.2 2 6.8 0.0 6.1 7 0 0 7 7 7 1 Alcohol acetyltransferase DivIC PF04977.10 ETS87212.1 - 0.35 10.3 0.5 1.2 8.6 0.3 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF600 PF04634.7 ETS87212.1 - 9.8 6.1 0.2 65 3.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Aminotran_4 PF01063.14 ETS87213.1 - 1.9e-22 79.8 0.0 2.4e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Peroxidase_2 PF01328.12 ETS87214.1 - 4.4e-11 42.0 0.4 2.9e-10 39.3 0.3 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 K_trans PF02705.11 ETS87216.1 - 1.3e-182 607.8 15.1 1.6e-182 607.6 10.5 1.0 1 0 0 1 1 1 1 K+ potassium transporter WSC PF01822.14 ETS87217.1 - 6.1e-10 38.8 18.6 2.8e-06 27.1 9.5 3.1 2 1 0 2 2 2 2 WSC domain SpoVAD PF07451.6 ETS87217.1 - 0.025 13.0 0.0 0.039 12.3 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) WSC PF01822.14 ETS87218.1 - 3.1e-06 27.0 11.0 3.1e-06 27.0 7.6 2.7 2 0 0 2 2 2 1 WSC domain WSC PF01822.14 ETS87220.1 - 8.7e-09 35.1 12.2 8.7e-09 35.1 8.4 2.5 3 0 0 3 3 3 1 WSC domain EBV-NA1 PF02905.9 ETS87221.1 - 0.0039 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Epstein Barr virus nuclear antigen-1, DNA-binding domain UCH PF00443.24 ETS87222.1 - 1.7e-61 207.7 0.0 1.7e-61 207.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 ETS87222.1 - 5.9e-31 108.0 3.4 2.6e-23 82.9 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.1 ETS87222.1 - 3.9 6.3 9.8 6.5 5.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 ETS87222.1 - 7.5 4.7 19.4 13 3.9 13.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.5 ETS87223.1 - 2.5e-14 53.0 0.0 4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 ETS87224.1 - 2.5e-41 142.0 17.7 3.6e-41 141.5 12.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Phospholip_A2_3 PF09056.6 ETS87225.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 RFX1_trans_act PF04589.8 ETS87226.1 - 0.74 9.5 4.6 0.21 11.3 1.0 1.6 2 0 0 2 2 2 0 RFX1 transcription activation region Fungal_trans PF04082.13 ETS87227.1 - 5.1e-20 71.4 3.3 7.6e-20 70.8 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87227.1 - 1.5e-07 31.1 9.6 2.3e-07 30.5 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS87228.1 - 8.2e-19 67.4 0.0 1.2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87228.1 - 4.6e-06 26.4 13.4 7.1e-06 25.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.6 ETS87229.1 - 1.2e-99 334.2 1.2 3.5e-99 332.6 0.9 1.6 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 ETS87229.1 - 1.8e-06 28.0 0.5 6.7e-06 26.1 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 ETS87229.1 - 0.0047 16.3 0.1 0.0089 15.4 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 ETS87229.1 - 0.0072 16.0 2.6 0.75 9.5 1.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87229.1 - 0.014 14.9 0.1 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2855 PF11017.3 ETS87230.1 - 7.7e-51 173.0 0.0 8.9e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Inositol_P PF00459.20 ETS87232.1 - 1.9e-40 138.8 0.2 5.1e-40 137.4 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family FAD_binding_3 PF01494.14 ETS87233.1 - 4.4e-20 72.0 0.1 3.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS87233.1 - 6.6e-09 35.1 0.6 1.7e-06 27.2 0.3 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS87233.1 - 2.4e-07 31.0 0.1 7.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS87233.1 - 1.9e-05 24.6 0.1 0.00015 21.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS87233.1 - 0.00019 21.3 0.0 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS87233.1 - 0.0077 14.9 0.0 0.1 11.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 ETS87233.1 - 0.0088 14.9 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS87233.1 - 0.0097 14.8 0.1 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 ETS87233.1 - 0.01 14.9 0.1 0.044 12.8 0.0 1.8 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 ETS87233.1 - 0.016 14.8 0.4 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 ETS87233.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 ETS87233.1 - 0.03 13.7 0.1 0.081 12.3 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Tir_receptor_N PF07490.6 ETS87233.1 - 0.036 13.6 0.1 0.1 12.1 0.0 1.6 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) N-terminus FAD_oxidored PF12831.2 ETS87233.1 - 0.046 12.8 0.1 0.17 10.9 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 ETS87233.1 - 0.051 14.0 0.3 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 ETS87233.1 - 0.066 12.0 0.2 0.1 11.4 0.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 ETS87233.1 - 0.077 13.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS87233.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 ETS87233.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 ETS87233.1 - 0.33 9.8 1.1 0.35 9.7 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase HsbA PF12296.3 ETS87234.1 - 2.9e-24 85.2 8.7 5.1e-24 84.5 6.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Sec10 PF07393.6 ETS87234.1 - 0.035 12.3 0.2 0.042 12.0 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 SNF5 PF04855.7 ETS87235.1 - 3.2e-84 282.2 0.0 4.4e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 ETS87235.1 - 6.7e-05 22.1 3.1 0.0002 20.6 2.2 1.9 1 0 0 1 1 1 1 GATA zinc finger Mito_carr PF00153.22 ETS87236.1 - 7.9e-47 156.9 9.2 3.1e-18 65.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4142 PF13628.1 ETS87236.1 - 0.017 15.1 0.3 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) vATP-synt_E PF01991.13 ETS87236.1 - 0.61 9.3 2.6 0.85 8.8 1.8 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Clr5 PF14420.1 ETS87237.1 - 7.9e-20 70.5 0.9 1.4e-19 69.6 0.6 1.4 1 0 0 1 1 1 1 Clr5 domain CBS PF00571.23 ETS87238.1 - 0.00011 21.9 0.0 0.021 14.5 0.0 3.0 2 1 0 2 2 2 1 CBS domain DUF4165 PF13752.1 ETS87238.1 - 0.035 13.8 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Tricorn_C1 PF14684.1 ETS87238.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain Epimerase PF01370.16 ETS87240.1 - 4.8e-20 71.9 0.0 6.8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 ETS87240.1 - 6.4e-11 41.6 0.0 1.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 ETS87240.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS87240.1 - 0.00018 21.5 0.0 0.00047 20.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS87240.1 - 0.00081 18.1 0.0 0.0064 15.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 ETS87240.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Saccharop_dh PF03435.13 ETS87240.1 - 0.043 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 ETS87240.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 ETS87240.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain F_actin_cap_B PF01115.12 ETS87241.1 - 6.8e-106 352.8 0.0 7.9e-106 352.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 ETS87241.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like F-actin_cap_A PF01267.12 ETS87241.1 - 0.14 11.1 0.1 0.58 9.1 0.0 1.9 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Ferric_reduct PF01794.14 ETS87242.1 - 5.5e-16 58.8 10.5 5.5e-16 58.8 7.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS87242.1 - 2.9e-10 40.2 0.0 6.6e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS87242.1 - 6.1e-10 38.9 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 ETS87242.1 - 0.0022 18.5 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GST_N_3 PF13417.1 ETS87244.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 ETS87244.1 - 2.2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 ETS87244.1 - 3.8e-06 26.7 0.0 6.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 ETS87244.1 - 0.00026 20.9 0.1 0.00076 19.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS87244.1 - 0.00041 20.1 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS87244.1 - 0.0084 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADC PF06314.6 ETS87245.1 - 0.0018 17.6 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans PF04082.13 ETS87246.1 - 2.1e-17 62.8 0.4 3.4e-17 62.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87246.1 - 5.8e-09 35.7 8.3 1.3e-08 34.6 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-3c_N PF05470.7 ETS87246.1 - 2.2 6.2 3.7 3.2 5.7 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RXT2_N PF08595.6 ETS87246.1 - 5.3 6.8 10.0 3 7.6 1.8 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal MFS_1 PF07690.11 ETS87248.1 - 9.8e-48 162.6 42.0 9.8e-48 162.6 29.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS87248.1 - 1.7e-13 49.9 28.3 5.5e-13 48.3 19.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 ETS87248.1 - 1.6e-06 26.6 4.3 1.6e-06 26.6 3.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 ETS87248.1 - 0.00096 17.9 2.6 0.0015 17.3 1.8 1.2 1 0 0 1 1 1 1 BT1 family OATP PF03137.15 ETS87248.1 - 0.0011 17.0 10.6 0.021 12.9 0.2 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 ETS87249.1 - 1.4e-13 50.3 0.0 2.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HrpF PF06266.7 ETS87250.1 - 0.071 13.2 3.2 0.5 10.5 0.1 3.3 3 1 1 4 4 4 0 HrpF protein adh_short PF00106.20 ETS87251.1 - 1.8e-14 54.0 0.4 3.8e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS87251.1 - 1.5e-06 28.0 0.2 1.5e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 ETS87251.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sulfatase PF00884.18 ETS87252.1 - 4.5e-61 206.7 0.0 6.4e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 ETS87252.1 - 3.5e-05 23.3 0.0 9.7e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 ETS87253.1 - 4.2e-44 150.6 34.3 4.2e-44 150.6 23.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS87253.1 - 2.1e-11 43.0 12.1 2.1e-11 43.0 8.4 3.9 3 2 0 3 3 3 2 Sugar (and other) transporter UPF0233 PF06781.7 ETS87253.1 - 0.016 14.7 0.2 0.29 10.7 0.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Folate_carrier PF01770.13 ETS87253.1 - 0.02 13.4 1.8 0.26 9.7 0.2 2.7 3 0 0 3 3 3 0 Reduced folate carrier DUF1275 PF06912.6 ETS87254.1 - 1.5e-40 138.6 15.4 1.8e-40 138.3 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.17 ETS87255.1 - 3.1e-30 104.5 0.0 1.8e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 ETS87255.1 - 9.8e-28 95.4 1.2 1.1e-14 53.6 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 ETS87255.1 - 3.5e-08 32.7 0.0 0.00083 18.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 ETS87255.1 - 2.4e-07 30.5 0.3 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 ETS87255.1 - 0.00041 20.0 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase FdtA PF05523.6 ETS87255.1 - 0.012 15.0 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 WxcM-like, C-terminal ARD PF03079.9 ETS87255.1 - 0.024 14.6 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.2 ETS87255.1 - 0.052 13.3 0.3 0.44 10.4 0.1 2.5 2 1 1 3 3 3 0 ChrR Cupin-like domain 3-HAO PF06052.7 ETS87255.1 - 0.062 12.7 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 ETS87255.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Sulfate_transp PF00916.15 ETS87256.1 - 1.4e-54 185.0 5.7 2.7e-54 184.0 4.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETS87256.1 - 2.2e-28 97.7 1.9 2.2e-28 97.7 1.3 3.5 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 ETS87256.1 - 4.5e-06 26.0 0.0 9.8e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain 2-Hacid_dh_C PF02826.14 ETS87257.1 - 1.5e-55 187.1 0.1 3.3e-55 185.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 ETS87257.1 - 1.8e-31 108.3 0.0 2.5e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 ETS87257.1 - 3.7e-05 23.6 0.2 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 ETS87257.1 - 0.0017 17.7 0.1 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 ETS87257.1 - 0.021 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CompInhib_SCIN PF11546.3 ETS87257.1 - 0.066 13.0 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN FMO-like PF00743.14 ETS87258.1 - 1e-14 53.6 0.0 7.6e-14 50.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 ETS87258.1 - 2.5e-12 47.3 0.0 1.7e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 ETS87258.1 - 1.4e-06 27.4 0.0 5.6e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 ETS87258.1 - 0.0002 21.3 0.2 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS87258.1 - 0.00063 19.5 0.6 0.022 14.5 0.1 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS87258.1 - 0.0051 16.7 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 ETS87259.1 - 1.5e-31 109.4 33.4 2.6e-31 108.6 23.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Dicty_CAR PF05462.6 ETS87260.1 - 2.8e-10 39.6 9.5 5.2e-10 38.7 6.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 ETS87260.1 - 1.4e-05 24.8 14.1 2.3e-05 24.0 9.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Abhydrolase_3 PF07859.8 ETS87261.1 - 7.7e-46 156.3 0.0 1.6e-45 155.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 ETS87261.1 - 0.0018 17.0 0.5 0.0063 15.2 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 ETS87261.1 - 0.056 13.1 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAP3 PF10236.4 ETS87262.1 - 3.2e-83 279.2 0.0 4.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DSBA PF01323.15 ETS87262.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_16 PF13191.1 ETS87262.1 - 0.075 13.0 0.2 0.23 11.4 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain RRS1 PF04939.7 ETS87263.1 - 4.1e-47 159.7 2.0 4.6e-47 159.5 1.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 ETS87264.1 - 4.2e-28 97.8 0.0 6.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 ETS87265.1 - 1.4e-59 197.2 5.6 1e-13 50.5 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS87265.1 - 3.6e-41 140.0 0.0 3.2e-14 53.3 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS87265.1 - 2.7e-12 46.6 0.0 0.00016 21.6 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like MFS_1 PF07690.11 ETS87266.1 - 3.4e-18 65.4 37.4 3.4e-18 65.4 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4387 PF14330.1 ETS87268.1 - 8.4e-33 112.6 0.0 5.2e-32 110.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 ETS87268.1 - 1e-12 47.2 0.0 6.5e-12 44.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Phosphoprotein PF00922.12 ETS87268.1 - 0.098 11.8 1.4 0.49 9.5 0.3 2.1 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 ETS87269.1 - 2.2e-31 108.8 26.0 2.2e-31 108.8 18.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 ETS87269.1 - 0.002 18.1 10.2 0.23 11.4 0.5 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) RseC_MucC PF04246.7 ETS87269.1 - 0.4 10.2 5.5 0.41 10.2 1.8 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MCM PF00493.18 ETS87270.1 - 1.2e-134 448.3 0.0 1.8e-134 447.7 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS87270.1 - 3.2e-23 82.5 0.4 8.4e-23 81.1 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 ETS87270.1 - 1.6e-07 30.7 0.0 1.5e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 ETS87270.1 - 3.6e-06 26.7 0.0 1.7e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 ETS87270.1 - 0.0023 18.2 0.5 0.011 16.1 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS87270.1 - 0.018 14.6 0.0 0.067 12.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS87270.1 - 0.11 12.4 5.8 1.9 8.4 0.2 3.6 3 1 0 4 4 4 0 AAA ATPase domain CHASE2 PF05226.6 ETS87270.1 - 0.16 11.1 2.5 0.16 11.1 0.6 1.8 2 0 0 2 2 2 0 CHASE2 domain AAA PF00004.24 ETS87271.1 - 3e-56 189.2 0.0 3.1e-43 147.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 ETS87271.1 - 4.6e-28 97.0 0.1 9.7e-28 96.0 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 ETS87271.1 - 1.1e-10 41.7 3.2 2.1e-05 24.5 0.0 4.3 3 1 1 4 4 4 2 AAA ATPase domain NACHT PF05729.7 ETS87271.1 - 3.6e-07 29.9 0.4 0.00059 19.5 0.0 3.8 4 0 0 4 4 4 1 NACHT domain AAA_2 PF07724.9 ETS87271.1 - 1.4e-05 25.1 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 ETS87271.1 - 2.7e-05 24.0 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 ETS87271.1 - 2.9e-05 23.2 0.3 0.052 12.6 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_22 PF13401.1 ETS87271.1 - 3e-05 24.1 0.7 0.53 10.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 ETS87271.1 - 4.1e-05 23.4 0.0 0.49 10.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 ETS87271.1 - 5.8e-05 23.9 0.0 0.26 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 ETS87271.1 - 6.2e-05 22.1 0.0 0.012 14.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 ETS87271.1 - 0.00031 21.0 0.0 0.2 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 ETS87271.1 - 0.0012 18.4 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 ETS87271.1 - 0.0015 18.0 0.1 2 7.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 ETS87271.1 - 0.0018 18.3 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 ETS87271.1 - 0.0022 17.7 0.0 3.8 7.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 ETS87271.1 - 0.0022 16.8 0.0 1.4 7.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 ETS87271.1 - 0.0055 16.4 0.1 2.2 8.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 ETS87271.1 - 0.014 15.5 0.0 7.8 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 ETS87271.1 - 0.016 14.3 0.7 0.85 8.7 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 ETS87271.1 - 0.016 14.6 0.0 0.78 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 ETS87271.1 - 0.017 15.0 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 ETS87271.1 - 0.022 14.4 0.2 2.9 7.5 0.0 3.1 2 2 1 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 ETS87271.1 - 0.025 13.4 0.0 6.2 5.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 ETS87271.1 - 0.036 13.4 3.5 9.2 5.6 0.2 4.0 2 2 2 4 4 4 0 AAA domain AAA_28 PF13521.1 ETS87271.1 - 0.055 13.4 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 ETS87271.1 - 0.067 12.1 0.3 5.6 5.8 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.21 ETS87271.1 - 0.073 12.5 0.0 2.7 7.4 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain Pkinase PF00069.20 ETS87272.1 - 4.9e-53 179.9 0.0 6.4e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87272.1 - 6.1e-39 133.6 0.0 8.7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS87272.1 - 3.4e-05 22.9 0.0 8.6e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETS87272.1 - 0.0016 18.2 0.0 0.021 14.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 ETS87272.1 - 0.031 13.3 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2934 PF11154.3 ETS87272.1 - 0.19 11.1 0.1 0.41 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Telomere_reg-2 PF10193.4 ETS87273.1 - 1.2e-36 125.4 0.0 4.1e-36 123.7 0.0 1.9 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.16 ETS87274.1 - 4.1e-39 133.5 0.2 1.1e-38 132.1 0.1 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 ETS87274.1 - 8.7e-26 89.5 0.1 1.9e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 ETS87274.1 - 4.7e-24 83.7 0.1 9.6e-24 82.7 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 ETS87274.1 - 1.4e-12 46.7 1.6 1.4e-12 46.7 1.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 ETS87274.1 - 0.00013 21.4 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 ETS87274.1 - 0.00049 20.2 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 ETS87274.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 ETS87274.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Complex1_49kDa PF00346.14 ETS87276.1 - 1e-134 447.7 0.0 1.4e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Cys_Met_Meta_PP PF01053.15 ETS87279.1 - 3.3e-22 78.3 0.0 6.7e-22 77.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS87279.1 - 3.2e-06 26.3 0.0 5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II VTC PF09359.5 ETS87280.1 - 1.4e-97 326.1 0.6 2.2e-97 325.5 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 ETS87280.1 - 3.7e-22 79.4 9.9 2e-12 47.5 2.2 3.3 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 ETS87280.1 - 1.8e-12 47.2 1.1 4.3e-12 46.0 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ank_2 PF12796.2 ETS87281.1 - 7.5e-06 26.1 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 ETS87281.1 - 0.0097 16.0 0.0 3.6 8.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Nop14 PF04147.7 ETS87281.1 - 7.1 4.4 8.0 8.6 4.1 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 ETS87281.1 - 8.6 4.9 11.4 12 4.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hexokinase_2 PF03727.11 ETS87282.1 - 5.1e-89 297.6 0.0 6.4e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 ETS87282.1 - 4.3e-65 218.8 0.0 3.3e-64 216.0 0.0 1.9 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 ETS87283.1 - 1e-05 24.9 0.2 1.3e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Hexokinase DUF2884 PF11101.3 ETS87283.1 - 0.02 14.2 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) GMP_synt_C PF00958.17 ETS87283.1 - 0.059 13.0 0.0 0.087 12.5 0.0 1.5 1 1 0 1 1 1 0 GMP synthase C terminal domain Aldolase_II PF00596.16 ETS87283.1 - 0.071 12.7 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Ribophorin_I PF04597.9 ETS87284.1 - 3.2e-147 490.5 0.1 3.6e-147 490.3 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 ETS87285.1 - 4.1e-98 327.8 4.2 8.5e-98 326.8 2.9 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 ETS87285.1 - 0.18 11.9 2.3 6.2 7.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) FAD_binding_3 PF01494.14 ETS87286.1 - 1.6e-24 86.6 0.0 1.2e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS87286.1 - 5.8e-05 22.1 0.4 0.00041 19.3 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 ETS87286.1 - 7.2e-05 21.8 0.0 0.0062 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 ETS87286.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS87286.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 ETS87286.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 ETS87286.1 - 0.033 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase K_oxygenase PF13434.1 ETS87286.1 - 0.034 13.0 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 ETS87286.1 - 0.038 13.0 0.0 0.083 11.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family RNA_pol_A_bac PF01000.21 ETS87287.1 - 4.4e-24 84.7 0.0 9.7e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 ETS87287.1 - 1.9e-13 49.2 0.0 2.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MIT PF04212.13 ETS87288.1 - 0.0065 16.3 0.2 3 7.7 0.0 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Chitin_synth_1 PF01644.12 ETS87290.1 - 2.3e-65 219.3 0.0 3.9e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 ETS87290.1 - 8.8e-30 103.5 0.2 2.9e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 ETS87290.1 - 2.2e-24 84.9 0.0 4.2e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 ETS87290.1 - 2.8e-13 50.0 2.1 2.8e-13 50.0 1.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS87290.1 - 3.1e-09 36.9 0.0 7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 BTB PF00651.26 ETS87290.1 - 0.0024 17.8 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_2_N PF02837.13 ETS87291.1 - 5.1e-23 81.4 0.0 8.6e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 ETS87291.1 - 7.3e-15 54.6 0.0 1.9e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 ETS87291.1 - 3.1e-08 34.0 0.0 7.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MCM PF00493.18 ETS87292.1 - 1.7e-140 467.5 0.1 2.4e-140 467.0 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 ETS87292.1 - 5.5e-26 91.4 0.0 3.9e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 ETS87292.1 - 2e-06 27.5 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS87292.1 - 2e-05 23.8 0.0 0.00083 18.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 ETS87292.1 - 0.002 17.6 0.0 0.0069 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 ETS87292.1 - 0.31 9.6 7.6 0.022 13.4 1.1 1.9 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.15 ETS87293.1 - 2.3e-15 56.5 1.6 5.8e-15 55.2 1.1 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 ETS87294.1 - 5.3e-53 178.9 0.0 1.1e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 ETS87294.1 - 2.3e-28 98.7 0.0 4.4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.7 ETS87295.1 - 2.1e-95 319.2 0.0 2.9e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HAUS-augmin3 PF14932.1 ETS87295.1 - 0.063 12.4 0.4 0.13 11.4 0.2 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Imm15 PF15590.1 ETS87295.1 - 0.78 8.8 3.2 0.47 9.5 0.1 2.3 3 0 0 3 3 3 0 Immunity protein 15 THOC7 PF05615.8 ETS87296.1 - 1.2e-27 96.9 4.1 1.2e-27 96.9 2.9 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 ALIX_LYPXL_bnd PF13949.1 ETS87296.1 - 0.1 11.5 6.9 0.18 10.7 4.8 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CTD PF12815.2 ETS87296.1 - 0.25 11.7 20.4 0.38 11.1 9.9 2.4 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Atg14 PF10186.4 ETS87296.1 - 0.62 8.9 8.1 0.37 9.6 4.3 1.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mto2_bdg PF12808.2 ETS87296.1 - 0.96 9.6 8.3 0.4 10.8 0.4 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FUSC PF04632.7 ETS87296.1 - 1.6 7.0 7.7 2.1 6.6 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.6 ETS87296.1 - 1.7 8.4 9.1 1.5 8.6 3.6 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_DNA_bd PF12329.3 ETS87296.1 - 4.2 7.2 7.3 31 4.4 2.1 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 ETS87296.1 - 5.4 6.8 13.4 4.9 6.9 0.1 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.10 ETS87296.1 - 7.5 6.1 7.0 12 5.5 0.1 3.2 2 1 1 3 3 3 0 Septum formation initiator Med21 PF11221.3 ETS87296.1 - 7.6 6.5 12.6 2 8.3 0.3 2.9 2 1 1 3 3 3 0 Subunit 21 of Mediator complex TBCA PF02970.11 ETS87297.1 - 8.4e-17 61.0 8.6 1.7e-16 60.0 6.0 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Tropomyosin PF00261.15 ETS87297.1 - 0.014 14.5 7.9 0.017 14.2 5.5 1.1 1 0 0 1 1 1 0 Tropomyosin RasGAP_C PF03836.10 ETS87297.1 - 0.14 11.8 4.9 0.14 11.8 1.7 1.8 1 1 1 2 2 2 0 RasGAP C-terminus Cor1 PF04803.7 ETS87297.1 - 0.14 11.8 3.6 0.19 11.4 2.5 1.2 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region IncA PF04156.9 ETS87297.1 - 0.16 11.5 5.1 0.21 11.1 3.5 1.2 1 0 0 1 1 1 0 IncA protein Bacillus_HBL PF05791.6 ETS87297.1 - 0.2 11.0 4.2 1.5 8.1 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.1 ETS87297.1 - 0.3 9.9 9.1 0.32 9.8 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1151 PF06625.6 ETS87297.1 - 1 9.1 6.7 1.2 8.8 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) ISG65-75 PF11727.3 ETS87297.1 - 1.1 8.2 6.6 1.3 7.9 4.6 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein ATP-synt_B PF00430.13 ETS87297.1 - 2.6 7.8 12.0 5.9 6.7 7.4 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) XhlA PF10779.4 ETS87297.1 - 4.3 7.3 7.1 7.4 6.5 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.7 ETS87297.1 - 4.7 6.9 12.0 28 4.4 8.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 ETS87297.1 - 6.1 6.4 9.2 24 4.5 6.3 1.8 1 1 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 ETS87297.1 - 8.5 6.2 11.3 0.63 9.8 0.6 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Dynamin_N PF00350.18 ETS87298.1 - 1.8e-29 102.6 1.7 3.2e-29 101.9 0.5 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 ETS87298.1 - 1e-16 60.5 0.0 3.4e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 ETS87298.1 - 0.00014 21.8 0.0 0.0036 17.2 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 ETS87298.1 - 0.00044 20.7 0.2 0.0025 18.2 0.0 2.2 1 1 0 2 2 2 1 Miro-like protein Methyltransf_23 PF13489.1 ETS87299.1 - 1.6e-21 76.6 0.0 2.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87299.1 - 4.1e-12 45.9 0.0 6.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87299.1 - 5.1e-11 43.1 0.0 4.3e-10 40.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS87299.1 - 2.5e-08 34.2 0.0 5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87299.1 - 4.8e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87299.1 - 9.1e-05 22.7 0.0 0.00044 20.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 ETS87299.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 ETS87299.1 - 0.0018 17.6 0.0 0.004 16.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 ETS87299.1 - 0.0046 16.1 0.0 0.038 13.1 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 ETS87299.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 ETS87299.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 ETS87299.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 ETS87299.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW COX17 PF05051.8 ETS87300.1 - 4.6e-20 71.3 6.3 5.5e-20 71.1 4.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) adh_short PF00106.20 ETS87301.1 - 1.5e-31 109.5 0.6 2.4e-31 108.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87301.1 - 4.7e-20 72.3 0.5 5.8e-20 72.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87301.1 - 2.3e-11 43.7 0.4 4.4e-11 42.7 0.3 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 ETS87301.1 - 0.0017 17.4 0.1 0.03 13.3 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 ETS87301.1 - 0.011 15.1 1.1 0.088 12.2 0.7 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 ETS87301.1 - 0.032 14.0 0.2 0.08 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAD PF12710.2 ETS87301.1 - 0.032 14.3 0.2 0.14 12.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NAD_binding_2 PF03446.10 ETS87301.1 - 0.044 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HHH_5 PF14520.1 ETS87301.1 - 0.12 12.5 0.7 4.8 7.4 0.5 2.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain CBM_4_9 PF02018.12 ETS87302.1 - 8.5e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain Cutinase PF01083.17 ETS87304.1 - 1.9e-48 164.5 10.4 2.2e-48 164.3 7.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 ETS87304.1 - 0.00011 21.7 0.5 0.00019 20.9 0.1 1.6 1 1 1 2 2 2 1 PE-PPE domain Abhydrolase_1 PF00561.15 ETS87304.1 - 0.049 13.1 0.4 0.068 12.7 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS87304.1 - 0.066 13.0 0.6 0.083 12.7 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FrhB_FdhB_N PF04422.8 ETS87304.1 - 0.091 12.6 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DIOX_N PF14226.1 ETS87305.1 - 3.5e-20 72.6 0.0 8.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS87305.1 - 1e-11 44.9 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 ETS87305.1 - 0.067 12.6 0.1 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 ETS87306.1 - 4.8e-30 104.4 27.7 4.8e-30 104.4 19.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 ETS87306.1 - 3 8.0 10.9 0.1 12.7 0.3 3.5 3 0 0 3 3 3 0 PepSY-associated TM helix TPR_11 PF13414.1 ETS87307.1 - 2.9e-18 65.2 6.5 3e-15 55.6 2.3 2.5 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 ETS87307.1 - 6.3e-13 47.5 5.5 0.002 17.9 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 ETS87307.1 - 5.6e-12 44.7 4.2 0.0024 17.4 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 ETS87307.1 - 1e-09 38.7 10.5 6e-05 23.6 1.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 ETS87307.1 - 8.2e-08 31.8 0.5 0.0084 16.2 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 ETS87307.1 - 9e-07 29.0 8.8 0.04 14.5 2.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS87307.1 - 3.4e-05 23.6 4.3 0.00057 19.7 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS87307.1 - 4.4e-05 22.9 0.5 1.7 8.6 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 ETS87307.1 - 0.00018 21.7 3.4 0.0011 19.2 1.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 ETS87307.1 - 0.00045 20.5 2.8 0.65 10.2 1.0 2.2 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 ETS87307.1 - 0.00052 19.8 4.2 0.0077 16.0 1.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 ETS87307.1 - 0.0017 17.7 6.9 0.0017 17.7 4.7 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_10 PF13374.1 ETS87307.1 - 0.024 14.5 2.5 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 ETS87307.1 - 0.035 14.5 4.7 4.2 8.0 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 ETS87307.1 - 0.054 13.2 1.3 3 7.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4398 PF14346.1 ETS87307.1 - 5.6 7.0 11.9 41 4.3 7.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Acetyltransf_2 PF00797.12 ETS87308.1 - 1.8e-35 122.6 0.1 5e-35 121.2 0.0 1.7 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 ETS87308.1 - 0.067 13.3 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily ABC_tran PF00005.22 ETS87309.1 - 5.8e-31 107.6 0.2 1.4e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 ETS87309.1 - 8.8e-15 54.8 3.2 8.8e-15 54.8 2.2 2.0 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.1 ETS87309.1 - 9.6e-06 25.7 0.0 0.00049 20.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain PAM2 PF07145.10 ETS87309.1 - 9.7e-05 21.6 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_25 PF13481.1 ETS87309.1 - 0.017 14.5 0.1 0.07 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETS87309.1 - 0.02 14.3 0.1 0.049 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 ETS87309.1 - 0.035 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 ETS87309.1 - 0.039 13.5 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 ETS87309.1 - 0.046 14.5 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 ETS87309.1 - 0.08 12.8 0.1 0.41 10.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 ETS87309.1 - 0.096 12.6 0.2 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RINGv PF12906.2 ETS87310.1 - 1.5e-05 24.9 5.7 2.4e-05 24.2 3.9 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 ETS87310.1 - 0.00026 20.8 3.8 0.0005 19.9 2.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 ETS87310.1 - 0.00068 19.4 6.5 0.0011 18.7 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS87310.1 - 0.0068 16.4 3.4 0.012 15.6 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS87310.1 - 0.05 13.4 1.1 0.084 12.7 0.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 ETS87310.1 - 0.081 12.6 3.3 0.14 11.8 2.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 ETS87310.1 - 0.17 11.4 3.8 0.29 10.7 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.2 ETS87313.1 - 9.9e-49 163.6 0.4 3e-17 62.7 0.0 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87313.1 - 1.9e-43 144.1 0.2 4.7e-06 26.1 0.3 8.1 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 ETS87313.1 - 1.8e-30 104.2 2.7 8.3e-09 35.4 0.0 7.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS87313.1 - 2.1e-30 101.6 0.0 0.00052 19.9 0.1 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 ETS87313.1 - 2.2e-23 82.1 1.9 0.00012 22.5 0.0 7.5 2 1 5 7 7 7 5 Ankyrin repeats (many copies) HET PF06985.6 ETS87313.1 - 3.8e-22 78.9 8.8 1.9e-20 73.4 6.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 ETS87313.1 - 5.1e-09 36.0 0.1 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS87313.1 - 1.2e-05 25.3 0.1 9.5e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS87313.1 - 0.00063 19.8 0.0 0.0057 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS87313.1 - 0.008 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 ETS87313.1 - 0.033 13.1 0.0 0.9 8.4 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 ETS87313.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Annexin PF00191.15 ETS87314.1 - 1.1e-70 233.4 2.2 1.7e-20 72.6 0.0 4.4 4 1 0 4 4 4 4 Annexin ABC_tran PF00005.22 ETS87315.1 - 9.2e-46 155.5 0.0 8.7e-27 94.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 ETS87315.1 - 1.4e-29 103.3 28.2 5.2e-14 52.3 0.4 3.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 ETS87315.1 - 1.4e-14 53.8 0.0 0.00016 20.9 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 ETS87315.1 - 7.6e-08 32.6 0.1 0.028 14.4 0.0 4.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 ETS87315.1 - 3.1e-07 30.5 3.4 0.0068 16.4 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 ETS87315.1 - 1.2e-06 27.9 2.3 0.007 15.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 ETS87315.1 - 4.1e-06 27.2 1.8 0.00051 20.4 0.4 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 ETS87315.1 - 1.1e-05 25.5 0.1 0.14 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 ETS87315.1 - 3e-05 23.7 0.2 0.017 14.8 0.0 3.1 3 1 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 ETS87315.1 - 3.2e-05 23.4 0.0 0.082 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 ETS87315.1 - 0.00014 21.3 0.0 0.62 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 ETS87315.1 - 0.00017 20.8 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 ETS87315.1 - 0.0016 18.3 0.0 0.62 10.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 ETS87315.1 - 0.0054 16.4 0.1 0.071 12.7 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 ETS87315.1 - 0.015 14.2 1.4 1.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.1 ETS87315.1 - 0.017 14.9 0.0 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 ETS87315.1 - 0.03 14.0 1.2 2.2 8.1 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 ETS87315.1 - 0.034 13.6 0.3 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 ETS87315.1 - 0.054 13.3 2.0 0.14 11.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 ETS87315.1 - 0.073 12.5 1.7 0.49 9.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 ETS87315.1 - 0.08 12.8 0.0 12 5.9 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 ETS87315.1 - 0.14 12.4 0.0 23 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 ETS87315.1 - 0.18 12.3 0.0 4.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 ETS87315.1 - 0.23 11.2 0.1 35 4.1 0.0 3.3 3 0 0 3 3 3 0 Dynamin family NTPase_1 PF03266.10 ETS87315.1 - 0.23 11.1 0.1 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 ETS87315.1 - 0.32 11.2 0.0 40 4.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.1 ETS87315.1 - 0.36 10.3 0.3 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 ETS87315.1 - 0.36 9.4 0.9 1.1 7.8 0.0 2.1 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_15 PF13175.1 ETS87315.1 - 0.88 8.5 0.0 1.5 7.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 ETS87316.1 - 4.6e-18 64.3 2.4 7.5e-08 31.9 0.1 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat VIT1 PF01988.14 ETS87316.1 - 1.1 8.6 2.1 1.9 7.9 1.4 1.3 1 0 0 1 1 1 0 VIT family ATP-synt_E PF05680.7 ETS87317.1 - 7.8e-21 73.8 0.2 8e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3186 PF11382.3 ETS87317.1 - 0.015 14.4 0.1 0.018 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) GOLD_2 PF13897.1 ETS87317.1 - 0.043 14.0 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking ABC_trans_N PF14510.1 ETS87317.1 - 0.14 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Nucleoporin_FG PF13634.1 ETS87318.1 - 0.001 19.2 10.4 0.001 19.2 7.2 7.3 4 1 1 5 5 5 2 Nucleoporin FG repeat region WD40 PF00400.27 ETS87318.1 - 0.036 13.9 0.0 0.16 11.9 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat Daxx PF03344.10 ETS87318.1 - 0.16 10.3 11.8 0.4 9.1 8.2 1.6 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 ETS87318.1 - 0.25 9.1 13.6 0.53 8.1 9.4 1.4 1 0 0 1 1 1 0 Nop14-like family KxDL PF10241.4 ETS87318.1 - 3.1 7.7 5.8 19 5.2 1.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Proteasome PF00227.21 ETS87319.1 - 3.1e-43 147.2 0.1 4.1e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 ETS87319.1 - 8.3e-14 50.5 0.4 2.2e-13 49.2 0.3 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Acetyltransf_3 PF13302.1 ETS87320.1 - 1.6e-27 96.4 0.0 1.9e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS87320.1 - 1.3e-13 51.1 0.0 1.5e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS87320.1 - 2.2e-07 30.9 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS87320.1 - 1.7e-06 27.9 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family COPIIcoated_ERV PF07970.7 ETS87321.1 - 1.9e-71 240.2 0.1 1.1e-47 162.5 0.1 2.2 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 ETS87321.1 - 1.1e-34 118.2 0.0 3.8e-34 116.5 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 ETS87322.1 - 1.4e-13 50.9 8.2 0.002 18.7 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat CVNH PF08881.5 ETS87323.1 - 3.9e-07 30.2 0.1 8.7e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 CVNH domain zf-UBP PF02148.14 ETS87323.1 - 0.79 9.8 4.6 0.78 9.9 2.0 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Glyco_transf_17 PF04724.8 ETS87324.1 - 1.3e-50 172.3 1.4 2e-50 171.8 1.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Beta_elim_lyase PF01212.16 ETS87325.1 - 3.1e-70 236.6 0.0 5.2e-70 235.8 0.0 1.3 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 ETS87325.1 - 0.00058 18.2 0.0 0.001 17.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 ETS87325.1 - 0.06 12.3 0.1 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_2 PF12796.2 ETS87326.1 - 1.4e-53 179.1 0.0 3.5e-16 59.3 0.0 8.4 3 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87326.1 - 1.2e-41 138.4 11.3 1e-06 28.1 0.0 13.0 15 1 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.1 ETS87326.1 - 4.9e-35 118.7 2.9 0.00055 20.1 0.1 11.2 10 1 2 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS87326.1 - 8.5e-35 118.5 1.6 2e-06 28.1 0.0 11.5 9 3 4 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS87326.1 - 8.6e-31 102.9 1.9 0.0004 20.3 0.0 11.9 13 0 0 13 13 13 5 Ankyrin repeat Myc_N PF01056.13 ETS87326.1 - 0.0045 16.2 0.6 0.0045 16.2 0.4 2.8 3 0 0 3 3 3 1 Myc amino-terminal region Trehalase PF01204.13 ETS87327.1 - 1.7e-113 379.9 10.4 2e-112 376.4 7.2 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 ETS87327.1 - 8.3e-06 24.7 0.4 0.0001 21.1 0.1 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Sterol_MT_C PF08498.5 ETS87327.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal MMS19_N PF14500.1 ETS87328.1 - 1.2e-48 165.6 0.1 2.9e-48 164.3 0.1 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 ETS87328.1 - 1.8e-11 43.4 1.3 3.3e-09 35.9 0.0 3.8 2 2 1 4 4 4 1 RNAPII transcription regulator C-terminal THF_DHG_CYH PF00763.18 ETS87329.1 - 8e-20 71.0 0.1 1.1e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 ETS87329.1 - 1.9e-13 49.7 0.1 7.9e-09 34.7 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 ETS87329.1 - 0.054 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SPC25 PF06703.6 ETS87330.1 - 2.3e-54 183.3 0.3 2.7e-54 183.1 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 ETS87331.1 - 2.2e-52 177.0 0.8 3.2e-52 176.4 0.5 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Ni_hydr_CYTB PF01292.15 ETS87331.1 - 0.061 12.7 0.8 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 RNA_pol_Rbc25 PF08292.7 ETS87332.1 - 9.4e-33 112.9 0.3 1.3e-32 112.5 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 ETS87332.1 - 1.5e-14 53.8 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 ETS87332.1 - 0.036 14.1 0.0 0.074 13.1 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain EnY2 PF10163.4 ETS87332.1 - 0.1 12.5 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Transcription factor e(y)2 NUFIP1 PF10453.4 ETS87333.1 - 1.5e-07 30.8 0.1 1.5e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 ETS87333.1 - 0.018 14.7 2.8 0.032 13.9 2.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S8e PF01201.17 ETS87334.1 - 1.8e-35 121.9 6.5 1e-34 119.4 4.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 ETS87334.1 - 2 8.6 7.4 3.7 7.7 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Pkinase PF00069.20 ETS87336.1 - 9.1e-45 152.8 0.0 1.5e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87336.1 - 1.2e-19 70.4 0.0 2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS87336.1 - 0.00021 20.3 0.0 0.00047 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS87336.1 - 0.00049 19.9 0.0 0.61 9.7 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family PsaA_PsaB PF00223.14 ETS87336.1 - 0.036 12.1 0.0 0.052 11.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Flagellin_D3 PF08884.6 ETS87336.1 - 0.038 14.1 1.4 0.088 12.9 1.0 1.6 1 0 0 1 1 1 0 Flagellin D3 domain Ribosomal_60s PF00428.14 ETS87337.1 - 1.3e-28 99.2 13.0 1.5e-28 99.0 9.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.12 ETS87337.1 - 0.21 11.1 0.1 0.21 11.1 0.0 1.4 2 0 0 2 2 2 0 RibD C-terminal domain Sigma70_r1_1 PF03979.9 ETS87337.1 - 0.47 10.4 0.1 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SPT2 PF08243.6 ETS87338.1 - 1.4e-11 44.7 25.7 2.7e-10 40.5 17.9 2.3 1 1 0 1 1 1 1 SPT2 chromatin protein adh_short PF00106.20 ETS87339.1 - 3.3e-17 62.9 0.3 1.1e-16 61.1 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87339.1 - 1.4e-08 34.8 0.1 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87339.1 - 2.4e-06 27.3 0.4 4.1e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 KR domain PARP PF00644.15 ETS87340.1 - 1.4e-61 207.5 0.0 3.7e-61 206.1 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 ETS87340.1 - 9.4e-41 138.6 1.1 1.3e-40 138.1 0.7 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 ETS87340.1 - 2.3e-22 78.7 0.1 5.6e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 WGR domain Transp_cyt_pur PF02133.10 ETS87341.1 - 1.9e-148 494.6 35.5 2.2e-148 494.4 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box PF00646.28 ETS87342.1 - 0.0023 17.5 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS87342.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like Abhydrolase_6 PF12697.2 ETS87343.1 - 2.2e-21 76.8 0.2 3.1e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87343.1 - 9.7e-12 44.8 0.0 1.8e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 ETS87343.1 - 0.019 14.8 0.1 0.063 13.1 0.1 1.9 1 1 0 1 1 1 0 Putative lysophospholipase Cys_Met_Meta_PP PF01053.15 ETS87344.1 - 2.9e-138 460.3 0.1 3.3e-138 460.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS87344.1 - 3.1e-08 32.9 0.3 4.6e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 ETS87344.1 - 3.3e-06 26.0 1.0 6e-06 25.2 0.3 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 ETS87344.1 - 5.6e-06 25.6 2.6 8.6e-06 25.0 1.8 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 ETS87344.1 - 0.0077 15.3 1.1 0.02 14.0 0.8 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Terpene_synth_C PF03936.11 ETS87345.1 - 2.7e-19 69.4 0.1 2.8e-17 62.8 0.0 2.0 1 1 1 2 2 2 2 Terpene synthase family, metal binding domain Carbpep_Y_N PF05388.6 ETS87345.1 - 0.056 13.6 0.4 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide F-box-like PF12937.2 ETS87346.1 - 9.7e-06 25.2 0.1 2.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS87346.1 - 0.018 14.6 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.14 ETS87347.1 - 9.7e-16 57.7 0.1 7.4e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tubulin PF00091.20 ETS87348.1 - 7.4e-65 218.7 0.0 9.8e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 ETS87348.1 - 1.1e-43 148.3 0.0 1.6e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 ETS87348.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 ETS87349.1 - 1.1e-11 44.2 0.0 1.4e-08 34.2 0.0 3.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87349.1 - 1.6e-08 34.2 0.0 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87349.1 - 3.2e-08 33.4 0.0 7.1e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 ETS87350.1 - 6.5e-26 91.1 2.1 6.5e-26 91.1 1.4 4.5 3 2 0 3 3 3 1 Sds3-like DUF3452 PF11934.3 ETS87350.1 - 0.21 10.8 0.1 0.42 9.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) CLPTM1 PF05602.7 ETS87350.1 - 0.36 9.4 3.2 0.13 10.9 0.2 1.6 2 0 0 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Coiled-coil_56 PF09813.4 ETS87351.1 - 0.004 17.1 0.0 0.0041 17.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 ETS87352.1 - 2.7e-63 213.5 0.3 4.2e-63 212.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Erg28 PF03694.8 ETS87352.1 - 0.11 12.4 0.3 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Erg28 like protein Macoilin PF09726.4 ETS87353.1 - 0.036 12.3 29.6 0.032 12.5 19.4 1.5 1 1 0 1 1 1 0 Transmembrane protein WH2 PF02205.15 ETS87355.1 - 6.2e-10 38.3 1.2 6.2e-10 38.3 0.9 2.9 4 0 0 4 4 4 1 WH2 motif Virul_fac_BrkB PF03631.10 ETS87357.1 - 0.001 18.5 4.6 0.0014 18.0 3.2 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF1282 PF06930.7 ETS87357.1 - 0.001 18.7 3.5 0.0014 18.3 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Per1 PF04080.8 ETS87357.1 - 0.0011 18.4 3.3 0.0013 18.2 1.8 1.4 1 1 0 1 1 1 1 Per1-like DUF4010 PF13194.1 ETS87357.1 - 0.0015 17.9 2.2 0.026 13.8 1.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4010) DUF3169 PF11368.3 ETS87357.1 - 0.009 15.2 1.4 0.019 14.2 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3169) DUF2189 PF09955.4 ETS87357.1 - 0.0095 15.8 0.2 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2189) PRA1 PF03208.14 ETS87357.1 - 0.14 11.4 2.4 0.4 10.0 1.7 1.7 1 0 0 1 1 1 0 PRA1 family protein Yip1 PF04893.12 ETS87357.1 - 0.16 11.4 5.9 0.3 10.5 4.1 1.5 1 1 0 1 1 1 0 Yip1 domain DUF1774 PF08611.5 ETS87357.1 - 0.7 10.0 3.9 0.46 10.6 0.5 2.2 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1774) CHORD PF04968.7 ETS87358.1 - 3.1e-52 174.6 17.5 5.6e-26 90.5 3.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 ETS87358.1 - 1.1e-11 45.0 0.1 1.8e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 ETS87359.1 - 3.6e-15 55.9 0.0 4.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 ETS87359.1 - 1.7e-05 24.7 0.1 8e-05 22.5 0.0 2.1 1 1 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 ETS87359.1 - 0.02 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Aurora-A_bind PF09041.5 ETS87359.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aurora-A binding HpcH_HpaI PF03328.9 ETS87360.1 - 3.1e-38 130.8 0.0 3.6e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 ETS87360.1 - 0.0023 17.2 0.3 1.1 8.4 0.0 3.0 3 0 0 3 3 3 2 Phosphoenolpyruvate phosphomutase DUF2156 PF09924.4 ETS87360.1 - 0.034 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Sugar_tr PF00083.19 ETS87361.1 - 3e-78 263.4 24.1 3.8e-78 263.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS87361.1 - 1.5e-32 112.7 37.8 1.8e-23 82.8 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 ETS87361.1 - 0.00015 20.0 7.0 0.029 12.4 0.0 2.8 2 2 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 ETS87361.1 - 7.4 6.4 10.2 0.49 10.2 0.1 3.2 4 0 0 4 4 4 0 MFS_1 like family Zn_clus PF00172.13 ETS87362.1 - 2.2e-08 33.8 8.7 3.4e-08 33.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 ETS87362.1 - 4.6e-07 28.7 0.1 1e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 ETS87363.1 - 6.4e-23 81.0 0.0 1.1e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 ETS87363.1 - 6.1e-21 74.3 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 ETS87363.1 - 7.8e-18 64.2 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain PsaM PF07465.8 ETS87363.1 - 0.14 11.7 0.1 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) AAA_22 PF13401.1 ETS87364.1 - 5.6e-12 45.9 0.2 1.8e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS87364.1 - 2.1e-11 44.1 0.1 1.4e-10 41.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 ETS87364.1 - 1.9e-10 41.0 0.0 5.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 ETS87364.1 - 1.8e-05 24.3 0.4 0.00013 21.5 0.1 2.6 2 1 0 2 2 1 1 CDC6, C terminal NACHT PF05729.7 ETS87364.1 - 0.00045 19.9 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 ETS87364.1 - 0.00086 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 ETS87364.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS87364.1 - 0.0024 17.5 0.0 0.24 11.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 ETS87364.1 - 0.0026 17.5 0.1 0.011 15.4 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 ETS87364.1 - 0.0031 18.0 0.1 0.013 16.0 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 ETS87364.1 - 0.0046 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 ETS87364.1 - 0.0065 15.4 0.1 0.015 14.3 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain PPR_1 PF12854.2 ETS87364.1 - 0.011 15.1 0.1 0.052 13.0 0.0 2.1 2 0 0 2 2 2 0 PPR repeat AAA_32 PF13654.1 ETS87364.1 - 0.017 13.7 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETS87364.1 - 0.023 14.3 0.0 0.072 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain SseB_C PF14581.1 ETS87364.1 - 0.023 14.5 0.0 0.069 13.0 0.0 1.9 1 0 0 1 1 1 0 SseB protein C-terminal domain AAA_5 PF07728.9 ETS87364.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 ETS87364.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA12 PF10443.4 ETS87364.1 - 0.08 11.4 0.5 0.68 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein Arrestin_N PF00339.24 ETS87365.1 - 1.3e-16 60.7 0.0 1.6e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 ETS87365.1 - 2.1e-07 31.1 0.0 0.0047 17.0 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 ETS87365.1 - 0.06 12.1 0.0 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Ribosomal_L2_C PF03947.13 ETS87366.1 - 3.9e-45 152.8 1.8 3.9e-45 152.8 1.3 2.6 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 ETS87366.1 - 2.3e-26 91.5 0.4 4.5e-26 90.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 ETS87367.1 - 4.6e-45 152.2 0.1 2.1e-44 150.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 ETS87367.1 - 5.1e-33 113.5 0.1 1e-32 112.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Herpes_capsid PF06112.6 ETS87370.1 - 4.7 7.2 8.0 4.9 7.1 5.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ion_trans PF00520.26 ETS87371.1 - 9.7e-98 325.3 91.6 2e-32 112.0 10.5 5.2 4 1 0 4 4 4 4 Ion transport protein JSRP PF15312.1 ETS87371.1 - 1.5 8.8 6.1 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein PHD PF00628.24 ETS87372.1 - 6.8e-08 32.0 9.0 1.2e-07 31.2 6.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 ETS87372.1 - 0.0012 18.0 5.7 0.0024 17.1 4.0 1.5 1 0 0 1 1 1 1 PHD-finger HMG_box PF00505.14 ETS87373.1 - 8.1e-11 42.0 0.6 1.7e-10 40.9 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS87373.1 - 0.0013 19.0 0.5 0.0029 17.9 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Sec20 PF03908.8 ETS87374.1 - 7.2e-13 48.0 0.1 7.2e-13 48.0 0.1 2.4 4 0 0 4 4 4 1 Sec20 Mod_r PF07200.8 ETS87374.1 - 0.13 12.1 7.8 0.13 12.1 1.9 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3877 PF12993.2 ETS87374.1 - 0.14 11.7 0.6 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Muted PF14942.1 ETS87374.1 - 1.6 8.5 8.8 0.22 11.4 0.4 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein IncA PF04156.9 ETS87374.1 - 3.5 7.1 27.1 0.42 10.1 11.8 2.7 3 0 0 3 3 3 0 IncA protein DUF972 PF06156.8 ETS87374.1 - 8.5 6.7 8.2 17 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MRP_L53 PF10780.4 ETS87375.1 - 3.3e-17 62.2 0.1 4.5e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 ETS87376.1 - 1.8e-53 180.1 0.1 2.3e-53 179.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 ETS87377.1 - 2.8e-43 147.9 0.5 6.9e-43 146.6 0.4 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Abhydrolase_6 PF12697.2 ETS87378.1 - 2.6e-20 73.2 1.5 3.9e-20 72.7 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87378.1 - 4.6e-10 39.4 0.2 7.1e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87378.1 - 0.0019 17.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 ETS87378.1 - 0.0027 17.9 0.3 0.015 15.5 0.2 1.9 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 ETS87378.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Sld5 PF05916.6 ETS87379.1 - 1.5e-06 28.4 0.1 2.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein FMN_dh PF01070.13 ETS87380.1 - 2.3e-117 391.8 0.0 2.7e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 ETS87380.1 - 0.0001 21.3 0.1 0.0002 20.4 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 ETS87380.1 - 0.00024 20.2 0.4 0.21 10.6 0.0 2.9 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 ETS87380.1 - 0.0006 18.7 0.6 0.013 14.4 0.1 2.5 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS87380.1 - 0.0006 19.0 0.4 0.001 18.3 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS87380.1 - 0.026 13.7 0.0 0.066 12.4 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein IGPS PF00218.16 ETS87380.1 - 0.095 11.7 0.0 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Fungal_trans_2 PF11951.3 ETS87381.1 - 3.8e-56 190.3 0.0 5.4e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH PF00465.14 ETS87381.1 - 0.26 9.8 0.7 0.53 8.8 0.2 1.6 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Pro_isomerase PF00160.16 ETS87382.1 - 1.6e-50 171.3 0.1 4.6e-50 169.8 0.1 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 ETS87382.1 - 1.6e-13 49.9 0.1 9e-08 31.7 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4661 PF15576.1 ETS87383.1 - 0.82 9.2 5.5 0.94 9.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) IpaD PF06511.6 ETS87383.1 - 1.2 8.1 7.1 1.3 7.9 4.9 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD DEAD PF00270.24 ETS87384.1 - 4.8e-45 153.0 0.0 5.6e-44 149.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87384.1 - 1.1e-23 82.8 0.0 3e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 ETS87384.1 - 0.0012 17.6 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 ETS87384.1 - 0.042 13.6 0.0 0.69 9.7 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HMG_box_2 PF09011.5 ETS87385.1 - 4.2e-10 39.8 3.4 2.5e-07 30.9 0.4 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 ETS87385.1 - 5.7e-05 23.3 0.6 5.7e-05 23.3 0.4 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box Methyltransf_11 PF08241.7 ETS87387.1 - 1.1e-10 41.9 0.0 2.6e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS87387.1 - 0.00014 21.6 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87387.1 - 0.023 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87387.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain EF1_GNE PF00736.14 ETS87390.1 - 7.7e-31 105.6 2.7 1.3e-30 104.8 1.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 ETS87390.1 - 2.4e-09 37.1 10.4 2.4e-09 37.1 7.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cnd2 PF05786.9 ETS87390.1 - 0.076 11.5 1.9 0.1 11.1 1.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PRT_C PF08372.5 ETS87390.1 - 0.37 10.2 1.4 12 5.4 0.1 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FMN_dh PF01070.13 ETS87391.1 - 9.1e-130 432.6 0.2 1e-129 432.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 ETS87391.1 - 6.7e-09 35.0 0.0 1.7e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 ETS87391.1 - 9.4e-08 31.5 0.6 9.4e-08 31.5 0.4 1.9 2 1 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 ETS87391.1 - 1.8e-05 23.9 0.4 0.0011 18.1 0.1 2.6 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 ETS87391.1 - 2.7e-05 23.5 0.1 0.011 15.0 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.12 ETS87391.1 - 9.2e-05 21.5 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 ETS87391.1 - 0.00028 19.9 0.1 0.00083 18.3 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 ETS87391.1 - 0.031 13.5 1.0 6.6 5.8 0.0 3.0 2 1 0 3 3 3 0 PcrB family AAA_2 PF07724.9 ETS87392.1 - 1.2e-44 152.2 0.0 7.3e-44 149.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 ETS87392.1 - 1.5e-24 85.7 1.8 1.8e-24 85.4 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 ETS87392.1 - 1.1e-19 70.9 0.0 1.8e-10 41.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 ETS87392.1 - 1.4e-12 47.5 0.0 9.6e-09 35.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 ETS87392.1 - 1.4e-12 47.9 8.3 0.00024 21.1 0.0 5.2 3 2 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 ETS87392.1 - 2.7e-10 40.4 1.8 0.00036 20.6 0.0 3.5 3 2 1 4 4 2 2 AAA domain Sigma54_activat PF00158.21 ETS87392.1 - 2.6e-07 30.2 0.2 7.7e-05 22.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 ETS87392.1 - 1.5e-06 28.9 3.0 0.0051 17.6 0.0 4.0 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 ETS87392.1 - 3.4e-06 26.9 7.7 0.035 13.7 0.2 4.6 3 2 0 3 3 3 2 Archaeal ATPase AAA_14 PF13173.1 ETS87392.1 - 4.5e-06 26.5 0.0 0.05 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 ETS87392.1 - 5.7e-06 26.0 0.1 0.12 12.0 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 ETS87392.1 - 1.8e-05 25.0 3.0 0.062 13.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 ETS87392.1 - 6.6e-05 22.5 0.1 0.02 14.6 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain MobB PF03205.9 ETS87392.1 - 0.00011 21.9 0.0 0.021 14.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 ETS87392.1 - 0.00055 19.3 0.0 0.9 8.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 ETS87392.1 - 0.0019 18.1 0.5 6.2 6.7 0.0 3.8 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 ETS87392.1 - 0.002 18.2 0.0 0.29 11.3 0.0 2.9 2 1 0 2 2 2 1 RNA helicase SRP54 PF00448.17 ETS87392.1 - 0.002 17.5 0.0 0.08 12.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 ETS87392.1 - 0.0062 16.1 0.3 0.95 9.0 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 ETS87392.1 - 0.0079 16.0 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 ETS87392.1 - 0.0088 15.5 0.0 0.15 11.4 0.0 3.0 2 2 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 ETS87392.1 - 0.009 16.3 1.6 0.86 9.8 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 ETS87392.1 - 0.013 14.7 0.0 3.2 6.8 0.0 3.0 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 ETS87392.1 - 0.013 14.6 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 ETS87392.1 - 0.016 13.8 0.0 3.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.8 ETS87392.1 - 0.019 13.8 0.3 0.88 8.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 ETS87392.1 - 0.026 13.9 0.3 3.5 6.9 0.0 2.8 2 2 0 2 2 2 0 AAA domain ResIII PF04851.10 ETS87392.1 - 0.027 14.3 2.4 5.9 6.6 0.0 3.6 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit PhoH PF02562.11 ETS87392.1 - 0.027 13.7 0.0 0.82 8.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 ETS87392.1 - 0.029 13.9 0.0 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 ETS87392.1 - 0.032 13.5 3.9 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 ETS87392.1 - 0.038 12.9 0.0 0.98 8.2 0.0 2.6 3 0 0 3 3 3 0 PIF1-like helicase PduV-EutP PF10662.4 ETS87392.1 - 0.053 13.0 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 ETS87392.1 - 0.098 12.2 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 ETS87392.1 - 0.12 11.9 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CENP-F_leu_zip PF10473.4 ETS87392.1 - 0.12 12.1 17.4 0.85 9.4 12.1 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OEP PF02321.13 ETS87392.1 - 0.41 10.2 12.0 0.9 9.1 8.3 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein APG6 PF04111.7 ETS87392.1 - 0.49 9.3 8.9 0.83 8.6 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 ETS87392.1 - 1.1 8.8 13.7 2.1 7.9 9.5 1.4 1 0 0 1 1 1 0 Mnd1 family DUF2968 PF11180.3 ETS87392.1 - 1.3 8.3 11.7 2.9 7.2 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Bacillus_HBL PF05791.6 ETS87392.1 - 2 7.7 7.1 1.2 8.4 3.4 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 ETS87392.1 - 2.2 7.1 10.4 4.1 6.2 7.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4349 PF14257.1 ETS87392.1 - 5.5 6.1 15.3 5.5 6.1 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) OmpH PF03938.9 ETS87392.1 - 5.9 6.8 11.5 19 5.1 8.0 1.8 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 ETS87392.1 - 6.9 4.3 4.9 9.8 3.8 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 ETS87392.1 - 9 6.5 19.2 3.1e+02 1.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 ETS87392.1 - 9.2 5.8 14.7 24 4.4 10.2 1.6 1 0 0 1 1 1 0 IncA protein ATP11 PF06644.6 ETS87393.1 - 2.5e-72 243.6 0.0 2.9e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein AMP-binding PF00501.23 ETS87394.1 - 4.4e-90 302.0 0.0 5.7e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 ETS87394.1 - 6.9e-12 46.1 0.1 1.3e-11 45.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydro_lipase PF04083.11 ETS87395.1 - 2.7e-20 71.4 0.0 5.7e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 ETS87395.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 ETS87396.1 - 2.4e-51 173.3 0.0 4.9e-43 146.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 ETS87396.1 - 8.7e-07 29.7 0.0 0.00044 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 ETS87396.1 - 2.4e-06 27.0 0.1 0.00037 19.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS87396.1 - 0.00021 20.4 0.0 0.00058 18.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 ETS87396.1 - 0.0003 20.9 0.1 0.0046 17.0 0.0 2.8 2 2 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 ETS87396.1 - 0.00066 18.6 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 ETS87396.1 - 0.0007 19.6 6.5 0.024 14.6 0.0 4.4 4 1 1 5 5 5 1 AAA ATPase domain IstB_IS21 PF01695.12 ETS87396.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 ETS87396.1 - 0.0012 19.0 0.0 0.033 14.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 ETS87396.1 - 0.0029 17.5 0.0 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 ETS87396.1 - 0.0034 17.1 0.0 0.017 14.8 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 ETS87396.1 - 0.0039 17.0 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 ETS87396.1 - 0.0087 14.8 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 ETS87396.1 - 0.02 14.6 0.0 0.082 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 ETS87396.1 - 0.021 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 ETS87396.1 - 0.03 13.4 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 ETS87396.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 ETS87396.1 - 0.039 13.8 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 ETS87396.1 - 0.048 13.9 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 ETS87396.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 ETS87396.1 - 0.082 11.8 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 ETS87396.1 - 0.22 10.4 0.0 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PPV_E1_C PF00519.12 ETS87396.1 - 0.25 9.8 0.0 0.43 9.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Abhydrolase_6 PF12697.2 ETS87398.1 - 7.6e-07 29.2 0.0 4.5e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87398.1 - 3e-06 27.0 0.0 8.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87398.1 - 3.2e-06 26.8 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS87398.1 - 4.4e-05 22.7 0.0 0.00079 18.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 ETS87398.1 - 0.045 13.1 0.0 0.17 11.2 0.0 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3329 PF11808.3 ETS87399.1 - 0.082 12.9 4.4 3.5 7.7 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) CwfJ_C_1 PF04677.10 ETS87400.1 - 3.9e-26 91.0 0.0 6.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 ETS87400.1 - 8e-21 74.3 0.1 1.6e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 ETS87401.1 - 2e-41 140.7 0.0 8e-41 138.7 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT_2 PF13646.1 ETS87401.1 - 7.4e-07 29.3 15.6 0.031 14.5 0.1 9.1 11 1 0 11 11 11 2 HEAT repeats HEAT PF02985.17 ETS87401.1 - 3.2e-05 23.6 12.2 0.46 10.6 0.0 9.0 9 0 0 9 9 9 2 HEAT repeat Arm PF00514.18 ETS87401.1 - 0.0058 16.4 1.6 56 3.7 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 ETS87401.1 - 0.029 14.8 13.4 28 5.3 0.0 8.6 9 0 0 9 9 9 0 HEAT-like repeat zf-DNL PF05180.7 ETS87402.1 - 6.5e-27 93.0 0.2 1e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 ETS87402.1 - 0.00085 18.7 0.3 0.0018 17.7 0.2 1.5 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.8 ETS87402.1 - 0.073 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cullin PF00888.17 ETS87403.1 - 1.1e-119 400.7 0.3 1.3e-119 400.3 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 ETS87403.1 - 3e-24 84.6 1.7 7.7e-24 83.3 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Ndc80_HEC PF03801.8 ETS87404.1 - 0.21 11.0 2.4 0.32 10.4 1.7 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family CAF-1_p150 PF11600.3 ETS87404.1 - 0.85 8.9 10.7 1.5 8.1 7.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 ETS87404.1 - 1.8 8.1 6.5 2.9 7.4 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Corona_nucleoca PF00937.13 ETS87404.1 - 6.9 5.5 12.3 9.2 5.0 8.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2413 PF10310.4 ETS87404.1 - 7.2 5.2 7.6 1.1 7.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Polysacc_deac_1 PF01522.16 ETS87407.1 - 3.2e-13 49.4 0.0 6.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DPPIV_N PF00930.16 ETS87408.1 - 3.9e-106 354.5 0.4 5e-106 354.2 0.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 ETS87408.1 - 7.5e-54 182.1 2.4 1.3e-53 181.4 1.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS87408.1 - 3.6e-09 36.5 0.2 7.8e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS87408.1 - 4e-05 23.6 0.2 0.0005 20.0 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 ETS87408.1 - 0.00011 21.7 7.4 0.00024 20.6 1.8 2.7 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 ETS87408.1 - 0.1 11.8 0.1 0.47 9.7 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family ICMT PF04140.9 ETS87409.1 - 2.5e-10 40.4 0.2 2e-08 34.3 0.1 2.3 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 ETS87409.1 - 3.3e-07 30.3 0.3 1.4e-05 25.0 0.1 2.4 1 1 0 2 2 2 1 Phospholipid methyltransferase Cu-oxidase_3 PF07732.10 ETS87410.1 - 1.6e-40 137.5 5.1 1.8e-39 134.1 1.7 3.4 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 ETS87410.1 - 2e-39 134.2 13.7 2.8e-39 133.8 0.7 3.4 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 ETS87410.1 - 1.5e-37 128.9 0.2 1.5e-37 128.9 0.1 2.2 2 1 1 3 3 3 1 Multicopper oxidase Rhamnogal_lyase PF06045.6 ETS87411.1 - 0.04 13.2 0.1 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family Pkinase PF00069.20 ETS87414.1 - 4.8e-09 35.7 0.0 9.2e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87414.1 - 2.2e-05 23.6 0.0 0.015 14.3 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 ETS87414.1 - 0.00034 20.4 0.1 0.013 15.2 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_2 PF00703.16 ETS87415.1 - 3e-10 40.5 0.1 1e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 ETS87415.1 - 4e-08 32.9 0.1 8.4e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 ETS87415.1 - 0.00041 19.3 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain SpoIIIAH PF12685.2 ETS87417.1 - 0.08 12.4 2.6 0.2 11.1 1.8 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein DnaJ PF00226.26 ETS87418.1 - 1.4e-11 43.9 0.0 2.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.17 ETS87419.1 - 5.1e-72 242.8 0.0 6.5e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 ETS87420.1 - 2.7e-20 71.8 2.2 4.6e-20 71.1 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 ETS87420.1 - 0.00041 20.3 0.4 0.00061 19.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF1183 PF06682.7 ETS87420.1 - 2.6 7.5 10.5 7.8 6.0 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 ETS87420.1 - 2.9 7.5 9.6 0.26 10.9 2.7 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 ETS87420.1 - 3.8 7.7 10.6 3 8.0 3.9 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF1509 PF07420.6 ETS87421.1 - 3.5 6.8 6.6 4.9 6.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PRA1 PF03208.14 ETS87422.1 - 7.8e-35 119.4 2.0 7.8e-35 119.4 1.4 1.8 2 0 0 2 2 2 1 PRA1 family protein IncA PF04156.9 ETS87422.1 - 1.6 8.2 10.2 8.4 5.9 7.1 2.0 1 1 0 1 1 1 0 IncA protein Methyltransf_23 PF13489.1 ETS87423.1 - 5.4e-15 55.4 0.0 8.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 ETS87423.1 - 1.7e-14 53.5 0.0 2.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 ETS87423.1 - 8.5e-08 32.5 0.0 3.3e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87423.1 - 1.1e-05 25.7 0.0 3.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87423.1 - 1.4e-05 25.6 0.0 3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87423.1 - 1.8e-05 25.0 0.0 5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87423.1 - 1.9e-05 24.2 0.0 0.00016 21.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS87423.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETS87423.1 - 0.0018 17.6 0.0 0.019 14.3 0.0 2.3 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW MTS PF05175.9 ETS87423.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PITH PF06201.8 ETS87424.1 - 3.4e-43 147.0 0.2 4.6e-43 146.5 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 ETS87424.1 - 4.5e-25 87.3 0.0 7.4e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 ETS87424.1 - 3.4e-07 30.2 0.0 0.00071 19.6 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS87424.1 - 7e-06 26.2 0.2 3.8e-05 23.8 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 ETS87424.1 - 0.017 14.7 0.2 0.94 9.1 0.0 2.4 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.1 ETS87424.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 ETS87424.1 - 0.023 14.2 0.1 0.13 11.8 0.0 2.0 1 1 1 2 2 2 0 Redoxin Thioredoxin_7 PF13899.1 ETS87424.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_61 PF03443.9 ETS87426.1 - 9.9e-75 251.0 2.7 1.1e-74 250.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 ETS87426.1 - 2.6e-06 26.9 9.5 7.6e-06 25.4 6.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF936 PF06075.7 ETS87426.1 - 0.1 11.5 11.0 0.13 11.1 7.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) TFIIA PF03153.8 ETS87426.1 - 2.8 7.7 10.0 3.8 7.3 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M14 PF00246.19 ETS87427.1 - 2.6e-68 230.6 0.0 3.2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 ETS87427.1 - 0.00025 20.6 0.9 0.00055 19.5 0.1 2.1 3 0 0 3 3 3 1 Carboxypeptidase activation peptide adh_short_C2 PF13561.1 ETS87428.1 - 6.2e-18 65.4 0.1 4e-17 62.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS87428.1 - 1.3e-17 64.2 2.6 1.2e-16 61.0 1.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS87428.1 - 8.2e-09 35.3 0.2 1.9e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 ETS87428.1 - 0.00056 19.9 0.5 0.0025 17.8 0.2 1.9 2 0 0 2 2 2 1 NADH(P)-binding YjeF_N PF03853.10 ETS87428.1 - 0.046 13.3 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Saccharop_dh PF03435.13 ETS87428.1 - 0.057 12.3 0.3 0.1 11.5 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 ETS87428.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.7 ETS87429.1 - 2.2e-24 85.2 1.0 3.9e-24 84.5 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 ETS87429.1 - 2.3e-22 78.9 0.1 3.4e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 ETS87429.1 - 0.001 18.2 0.1 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 ETS87429.1 - 0.0064 17.3 0.0 0.014 16.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 ETS87429.1 - 0.015 15.0 0.3 0.015 15.0 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 ETS87429.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.13 ETS87429.1 - 0.13 12.3 0.2 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_3_C PF01915.17 ETS87430.1 - 3.9e-54 183.5 0.0 5.9e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 ETS87430.1 - 2.9e-52 177.5 0.0 4.3e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 ETS87430.1 - 3.4e-11 42.9 0.0 7.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 ETS87430.1 - 7.7e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 ETS87430.1 - 0.048 13.7 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 CARDB Fungal_trans PF04082.13 ETS87431.1 - 8.1e-07 28.1 0.0 1.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87431.1 - 3.3e-05 23.6 12.2 5.7e-05 22.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 ETS87431.1 - 0.32 10.3 1.1 2.8 7.3 0.6 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin T2SM PF04612.7 ETS87431.1 - 1.3 8.8 3.9 3.2 7.5 2.5 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Abhydrolase_6 PF12697.2 ETS87433.1 - 8e-18 65.1 6.3 8e-18 65.1 4.4 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87433.1 - 2.2e-10 40.4 0.0 4.6e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87433.1 - 3.2e-09 36.6 0.1 4.3e-08 33.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS87433.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 ETS87433.1 - 0.017 14.8 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 ETS87433.1 - 0.044 13.0 0.2 0.45 9.7 0.1 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 ETS87433.1 - 0.13 12.1 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein NAS PF03059.11 ETS87434.1 - 3.5e-64 216.6 0.0 1.1e-63 215.0 0.0 1.6 1 1 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_18 PF12847.2 ETS87434.1 - 0.0021 18.6 0.0 0.0042 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87434.1 - 0.0046 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TFIIF_alpha PF05793.7 ETS87434.1 - 0.57 8.4 7.5 0.83 7.9 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.7 ETS87434.1 - 4.5 6.4 7.7 7.2 5.7 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein RhoGAP PF00620.22 ETS87435.1 - 1.8e-40 138.0 0.1 7.9e-40 135.9 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 ETS87435.1 - 7.3e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 ETS87435.1 - 0.00019 21.6 0.0 0.00048 20.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 ETS87435.1 - 0.011 14.9 0.8 0.022 14.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PX PF00787.19 ETS87435.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 PX domain PH_8 PF15409.1 ETS87435.1 - 0.058 13.4 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PAT1 PF09770.4 ETS87437.1 - 3.9 5.5 14.3 4.5 5.3 9.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 ETS87440.1 - 0.00038 20.2 0.2 0.00074 19.2 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 Adeno_E3_CR2 PF02439.10 ETS87440.1 - 0.00042 19.7 1.9 0.00075 18.9 1.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 ETS87440.1 - 0.028 13.7 2.6 0.065 12.5 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neur_chan_memb PF02932.11 ETS87440.1 - 0.061 13.1 0.1 0.31 10.9 0.1 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rifin_STEVOR PF02009.11 ETS87440.1 - 0.095 12.3 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Herpes_gE PF02480.11 ETS87440.1 - 0.17 10.1 2.9 0.12 10.6 0.3 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 ETS87440.1 - 0.28 11.5 1.6 0.5 10.7 1.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 ETS87440.1 - 0.88 9.7 6.9 0.11 12.7 0.6 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PLRV_ORF5 PF01690.12 ETS87441.1 - 0.87 8.6 14.9 1.3 8.0 10.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Lamp PF01299.12 ETS87441.1 - 3.3 6.7 5.9 4.1 6.4 4.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF605 PF04652.11 ETS87441.1 - 3.4 6.9 14.4 3.4 6.9 10.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF1593 PF07632.6 ETS87443.1 - 2.6e-80 269.4 0.0 3.5e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 ETS87443.1 - 6.6e-05 21.4 0.0 8.9e-05 20.9 0.0 1.1 1 0 0 1 1 1 1 REJ domain Lactamase_B_2 PF12706.2 ETS87444.1 - 2.2e-20 73.0 0.0 3.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 ETS87444.1 - 7.4e-14 51.7 0.5 9.2e-13 48.2 0.4 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 ETS87444.1 - 0.025 14.2 10.3 0.15 11.6 3.1 3.5 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily Abhydrolase_6 PF12697.2 ETS87446.1 - 2e-17 63.8 0.0 2.5e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87446.1 - 5.2e-06 26.2 0.1 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87446.1 - 1.8e-05 24.3 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Acetyltransf_7 PF13508.1 ETS87447.1 - 4.4e-08 33.1 0.0 1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS87447.1 - 4.7e-07 29.7 0.1 1e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 ETS87447.1 - 1.8e-06 27.8 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS87447.1 - 1.4e-05 25.2 0.1 5.1e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain PD40 PF07676.7 ETS87448.1 - 2.5e-48 161.0 19.2 2.8e-09 36.4 0.6 9.8 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 ETS87448.1 - 3.3e-13 48.9 1.5 0.0043 15.7 0.0 6.6 4 2 2 7 7 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipocalin_3 PF12702.2 ETS87448.1 - 0.012 15.6 0.0 15 5.6 0.0 4.1 3 1 1 4 4 4 0 Lipocalin-like MscS_TM PF12794.2 ETS87449.1 - 0.015 13.9 0.2 0.021 13.4 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MFS_1 PF07690.11 ETS87450.1 - 1.5e-53 181.7 32.2 1.5e-53 181.7 22.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS87450.1 - 1.4e-09 37.1 18.5 1.4e-09 37.1 12.8 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 ETS87450.1 - 0.056 11.5 14.8 0.64 8.0 4.9 3.4 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 ETS87451.1 - 2.3e-50 171.4 0.2 3.4e-50 170.9 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 ETS87452.1 - 8.7e-08 31.1 1.2 1.3e-07 30.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tme5_EGF_like PF09064.5 ETS87453.1 - 0.0034 16.9 1.4 0.0089 15.6 1.0 1.7 1 0 0 1 1 1 1 Thrombomodulin like fifth domain, EGF-like DUF1680 PF07944.7 ETS87454.1 - 2.3e-25 88.8 0.0 3.5e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_32C PF08244.7 ETS87455.1 - 5.1e-18 65.2 0.1 1.1e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 ETS87455.1 - 3.4e-12 46.3 0.0 5.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.6 ETS87456.1 - 6.6e-25 87.8 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dimer_Tnp_hAT PF05699.9 ETS87457.1 - 1.6e-12 46.8 0.0 4.2e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 ETS87457.1 - 0.00072 19.5 0.1 0.0022 17.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) BSP_II PF05432.6 ETS87457.1 - 0.041 13.1 10.3 0.073 12.3 7.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2457 PF10446.4 ETS87457.1 - 0.093 11.4 15.2 0.0065 15.2 7.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) ShK PF01549.19 ETS87458.1 - 0.29 11.5 6.4 0.13 12.6 2.7 1.8 2 0 0 2 2 2 0 ShK domain-like Nairovirus_M PF07948.6 ETS87459.1 - 0.13 10.3 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DDE_1 PF03184.14 ETS87460.1 - 3.5e-38 130.9 0.0 6.4e-35 120.2 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease ABC2_membrane PF01061.19 ETS87461.1 - 2.3e-84 281.7 38.1 2e-43 147.9 7.2 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 ETS87461.1 - 2.1e-38 131.7 0.0 1.6e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 ETS87461.1 - 1.5e-21 75.9 0.0 4.1e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.1 ETS87461.1 - 1.1e-06 28.2 1.3 0.00044 19.7 0.1 3.3 4 0 0 4 4 3 1 AAA domain ABC2_membrane_3 PF12698.2 ETS87461.1 - 1.1e-06 27.9 30.5 0.0004 19.5 6.7 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 ETS87461.1 - 1.2e-05 25.2 0.0 4.8e-05 23.3 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 ETS87461.1 - 1.6e-05 24.1 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 ETS87461.1 - 8.4e-05 22.8 0.1 0.68 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS87461.1 - 0.00017 21.0 0.7 0.011 15.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS87461.1 - 0.00026 21.0 1.0 0.019 14.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 ETS87461.1 - 0.00066 19.1 1.0 0.18 11.2 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 ETS87461.1 - 0.00086 19.4 0.2 0.24 11.5 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 ETS87461.1 - 0.0019 17.8 0.6 1.5 8.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 ETS87461.1 - 0.0023 17.9 0.3 0.3 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 ETS87461.1 - 0.0026 17.7 0.0 0.35 10.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 ETS87461.1 - 0.0058 17.4 0.0 1.2 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 ETS87461.1 - 0.011 15.2 0.2 0.63 9.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 ETS87461.1 - 0.02 14.6 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase SMC_N PF02463.14 ETS87461.1 - 0.022 13.9 0.0 2.5 7.2 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 ETS87461.1 - 0.031 13.9 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 ETS87461.1 - 0.039 13.8 0.0 0.68 9.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 ETS87461.1 - 0.065 13.2 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 ETS87461.1 - 0.15 11.7 0.4 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 ETS87461.1 - 0.35 10.6 0.6 0.93 9.2 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF87 T2SE PF00437.15 ETS87461.1 - 0.37 9.6 0.3 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 ETS87461.1 - 0.57 10.4 0.0 1 9.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 ETS87462.1 - 2.7e-09 36.2 0.3 4.7e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87463.1 - 5.4 7.0 22.4 0.026 14.4 8.5 2.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 ETS87464.1 - 1.6e-57 195.0 23.0 1.9e-57 194.7 15.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 ETS87465.1 - 2.5e-32 111.8 0.0 3.7e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS87465.1 - 8.3e-23 80.5 0.0 1.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 ETS87466.1 - 2e-33 116.1 0.1 2.3e-33 115.9 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87466.1 - 7.8e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS87466.1 - 3.2e-18 65.8 0.8 1.2e-17 64.0 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 ETS87466.1 - 1.4e-07 30.2 0.0 1.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 ETS87466.1 - 8.7e-05 22.3 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 ETS87466.1 - 0.00082 18.8 0.2 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 ETS87466.1 - 0.0019 18.4 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 ETS87466.1 - 0.002 17.7 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 ETS87466.1 - 0.0025 17.4 0.1 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.7 ETS87466.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 ETS87466.1 - 0.018 14.5 0.8 0.037 13.5 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase DUF915 PF06028.6 ETS87466.1 - 0.023 13.7 0.4 0.12 11.3 0.0 2.1 1 1 2 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 ETS87466.1 - 0.034 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pro_CA PF00484.14 ETS87466.1 - 0.042 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase LIP PF03583.9 ETS87466.1 - 0.086 12.0 0.1 0.99 8.5 0.1 2.2 2 0 0 2 2 2 0 Secretory lipase Peptidase_S9 PF00326.16 ETS87466.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family 2OG-FeII_Oxy PF03171.15 ETS87467.1 - 2.2e-18 66.3 0.0 3.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 ETS87467.1 - 1.2e-15 58.0 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3435 PF11917.3 ETS87468.1 - 4.3e-16 58.6 0.0 1.5e-15 56.9 0.0 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3435) DJ-1_PfpI PF01965.19 ETS87469.1 - 1.3e-18 66.8 0.0 2e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 ETS87469.1 - 9.2e-10 37.8 0.0 1.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family NmrA PF05368.8 ETS87470.1 - 3e-05 23.3 0.0 4.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family SAP PF02037.22 ETS87471.1 - 1.3e-07 30.9 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 SAP domain Sulfatase PF00884.18 ETS87472.1 - 4.1e-61 206.8 0.0 5.5e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 ETS87472.1 - 2.3e-09 37.6 0.0 5.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 ETS87472.1 - 4.1e-06 26.3 0.0 0.00084 18.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 ETS87473.1 - 1e-28 100.0 22.0 1.5e-28 99.5 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HrpB7 PF09486.5 ETS87474.1 - 0.064 13.1 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Fungal_trans PF04082.13 ETS87475.1 - 9.1e-34 116.4 0.3 3.2e-33 114.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87475.1 - 1.3e-06 28.2 13.2 2e-06 27.6 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC32 PF14989.1 ETS87475.1 - 0.11 12.2 0.3 0.34 10.7 0.2 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing 32 Tyrosinase PF00264.15 ETS87476.1 - 3.9e-22 79.5 5.2 4.6e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase DUF3541 PF12060.3 ETS87476.1 - 0.1 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) LPAM_1 PF08139.7 ETS87476.1 - 1.6 9.1 4.3 3.2 8.1 3.0 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Dioxygenase_C PF00775.16 ETS87477.1 - 3.1e-10 39.6 2.1 1.7e-09 37.1 1.5 2.0 1 1 0 1 1 1 1 Dioxygenase Inhibitor_I53 PF11714.3 ETS87477.1 - 0.18 11.8 1.1 1.3 9.1 0.7 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DJ-1_PfpI PF01965.19 ETS87478.1 - 8.7e-10 38.2 0.0 1.4e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family HET PF06985.6 ETS87480.1 - 3.6e-22 79.0 0.1 7.6e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.13 ETS87481.1 - 5.6e-12 45.4 0.1 7.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1214 PF06742.6 ETS87482.1 - 5.9e-15 55.5 0.1 9.7e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) CBFD_NFYB_HMF PF00808.18 ETS87483.1 - 3.6e-10 39.7 0.1 8.2e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS87483.1 - 1.3e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RNB PF00773.14 ETS87484.1 - 2.1e-93 313.1 0.1 3.1e-93 312.6 0.1 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 ETS87484.1 - 1.8e-09 37.7 0.8 7e-09 35.8 0.2 2.3 2 0 0 2 2 2 1 PIN domain OB_RNB PF08206.6 ETS87484.1 - 0.066 12.7 1.0 0.39 10.2 0.0 2.6 3 0 0 3 3 3 0 Ribonuclease B OB domain CRC_subunit PF08624.5 ETS87485.1 - 5.7e-54 181.7 0.0 1e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DnaJ_CXXCXGXG PF00684.14 ETS87486.1 - 0.51 10.4 4.1 0.76 9.8 2.4 1.7 1 1 0 1 1 1 0 DnaJ central domain HAD PF12710.2 ETS87487.1 - 2.5e-17 63.6 0.2 3.2e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS87487.1 - 0.00083 19.6 2.0 0.002 18.3 0.6 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS87487.1 - 0.049 13.1 0.8 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIF_beta PF02270.10 ETS87488.1 - 1.9e-58 198.4 0.0 2.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit CBF PF03914.12 ETS87489.1 - 1.3e-46 158.0 1.2 2.9e-46 156.9 0.1 2.0 2 0 0 2 2 2 1 CBF/Mak21 family bZIP_1 PF00170.16 ETS87490.1 - 0.00012 21.9 10.8 0.00012 21.9 7.5 2.6 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 ETS87490.1 - 0.00017 21.3 8.9 0.00017 21.3 6.2 3.4 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.12 ETS87490.1 - 0.00033 20.8 8.7 0.00033 20.8 6.0 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor Sel1 PF08238.7 ETS87491.1 - 1e-21 76.8 7.2 1.7e-07 31.6 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat SRP-alpha_N PF04086.8 ETS87491.1 - 0.0032 16.8 3.1 0.005 16.2 2.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal TPR_6 PF13174.1 ETS87491.1 - 0.32 11.5 2.0 8.4 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 ETS87492.1 - 4.3e-33 114.4 41.0 4.3e-33 114.4 28.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Transferase PF02458.10 ETS87493.1 - 6e-23 80.9 0.0 5.7e-22 77.7 0.0 1.9 2 0 0 2 2 2 2 Transferase family zf-CCCH PF00642.19 ETS87494.1 - 5e-12 45.1 20.2 3.6e-05 23.3 0.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mt_ATP-synt_B PF05405.9 ETS87495.1 - 3.5e-53 179.3 4.7 4.6e-53 179.0 3.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 ETS87495.1 - 0.046 13.5 1.2 0.054 13.3 0.2 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) HECT_2 PF09814.4 ETS87496.1 - 2.5e-61 207.3 0.0 2.9e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 ETS87496.1 - 0.01 15.8 0.2 0.094 12.7 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4243 PF14027.1 ETS87497.1 - 5.1e-84 282.5 0.4 6.3e-84 282.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AgrB PF04647.10 ETS87497.1 - 0.69 8.9 3.7 0.26 10.3 0.8 1.4 2 0 0 2 2 2 0 Accessory gene regulator B Rad17 PF03215.10 ETS87498.1 - 1e-56 192.7 0.0 1.7e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 ETS87498.1 - 2.4e-05 24.5 0.0 9.8e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 ETS87498.1 - 0.00092 18.9 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 ETS87498.1 - 0.0049 17.0 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 ETS87498.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS87498.1 - 0.033 14.1 0.1 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 ETS87498.1 - 0.038 12.8 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 ETS87498.1 - 0.044 14.6 0.0 0.17 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 ETS87498.1 - 0.08 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 ETS87498.1 - 0.092 12.3 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 ETS87498.1 - 0.11 12.0 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 ETS87498.1 - 0.13 11.4 0.0 0.38 9.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 ETS87498.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Herpes_Helicase PF02689.9 ETS87498.1 - 0.47 8.1 0.0 0.7 7.5 0.0 1.1 1 0 0 1 1 1 0 Helicase TPT PF03151.11 ETS87499.1 - 1.4e-34 118.9 6.8 1.4e-34 118.9 4.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 ETS87499.1 - 0.00011 21.3 12.0 0.00011 21.3 8.3 1.4 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 ETS87499.1 - 0.0017 18.3 32.9 0.018 15.1 8.5 3.0 2 1 0 2 2 2 2 EamA-like transporter family CD99L2 PF12301.3 ETS87499.1 - 0.0064 16.1 2.9 0.0064 16.1 2.0 2.2 2 0 0 2 2 2 1 CD99 antigen like protein 2 Nucleo_P87 PF07267.6 ETS87499.1 - 0.18 10.4 6.4 0.25 9.9 4.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DAGAT PF03982.8 ETS87500.1 - 2.6e-95 318.5 0.0 3.3e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Peptidase_M22 PF00814.20 ETS87501.1 - 2.5e-47 161.6 0.0 3.3e-24 85.8 0.0 3.5 2 2 0 2 2 2 2 Glycoprotease family YycC PF14174.1 ETS87501.1 - 0.033 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein Proteasome PF00227.21 ETS87502.1 - 8.7e-50 168.6 0.3 1e-49 168.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit MFS_1 PF07690.11 ETS87503.1 - 3.7e-30 104.8 39.1 3.7e-30 104.8 27.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ctr PF04145.10 ETS87504.1 - 3.8e-14 52.9 0.0 5.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.14 ETS87505.1 - 3.1e-18 66.0 12.7 3.1e-18 66.0 8.8 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 ETS87505.1 - 2.6e-14 53.4 0.0 3.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 ETS87505.1 - 8.4e-12 44.9 0.0 2.2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 ETS87505.1 - 0.016 15.3 7.9 0.2 11.7 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Abhydrolase_1 PF00561.15 ETS87506.1 - 5e-07 29.5 0.0 7.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS87506.1 - 5.5e-07 29.6 0.3 9.6e-06 25.6 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87506.1 - 4.6e-05 23.2 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 ETS87506.1 - 0.05 12.1 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RRM_1 PF00076.17 ETS87507.1 - 6.3e-17 60.9 0.0 9.5e-17 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87507.1 - 8.8e-10 38.4 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87507.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 ETS87507.1 - 0.028 13.9 0.3 0.052 13.0 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PAT1 PF09770.4 ETS87507.1 - 0.19 9.9 10.3 0.22 9.7 7.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 6PGD PF00393.14 ETS87508.1 - 1.9e-134 447.4 0.0 2.3e-134 447.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 ETS87508.1 - 8.7e-41 139.4 0.0 1.3e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 ETS87508.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 ETS87508.1 - 0.089 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase SWI-SNF_Ssr4 PF08549.5 ETS87509.1 - 2.3e-188 627.6 22.2 4.1e-188 626.8 15.4 1.3 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Metal_resist PF13801.1 ETS87509.1 - 0.038 13.9 3.5 0.23 11.4 0.0 2.7 2 0 0 2 2 2 0 Heavy-metal resistance PI-PLC-X PF00388.14 ETS87512.1 - 1.6e-12 47.0 0.0 2.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SET PF00856.23 ETS87513.1 - 2.6e-12 47.3 0.1 9.6e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 SET domain ComZ PF10815.3 ETS87513.1 - 0.013 15.2 0.2 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 ComZ Apq12 PF12716.2 ETS87514.1 - 3.7e-07 29.7 10.3 5.6e-07 29.1 7.2 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 ETS87515.1 - 1.2e-72 244.2 0.0 2.9e-72 243.0 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 ETS87515.1 - 1.3e-05 25.9 0.0 3.8e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 ETS87515.1 - 0.00045 20.1 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 ETS87515.1 - 0.0029 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 ETS87515.1 - 0.0035 17.2 0.0 0.0092 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 ETS87515.1 - 0.0053 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 ETS87515.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 ETS87515.1 - 0.02 14.8 0.0 0.06 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 ETS87515.1 - 0.022 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 ETS87515.1 - 0.024 14.0 0.0 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 ETS87515.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 ETS87515.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 ETS87515.1 - 0.037 13.9 0.0 0.095 12.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 ETS87515.1 - 0.039 12.9 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain GTP_EFTU PF00009.22 ETS87515.1 - 0.039 13.3 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 ETS87515.1 - 0.043 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 ETS87515.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 ETS87515.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain PPV_E1_C PF00519.12 ETS87515.1 - 0.052 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.22 ETS87515.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 ETS87515.1 - 0.072 12.5 0.1 6.8 6.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 ETS87515.1 - 0.096 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 ETS87515.1 - 0.098 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 ETS87515.1 - 0.11 11.9 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 ETS87515.1 - 0.12 12.7 0.0 0.55 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain S-AdoMet_synt_C PF02773.11 ETS87516.1 - 2.1e-74 247.7 0.8 4e-74 246.8 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 ETS87516.1 - 4.8e-46 155.6 0.0 8.5e-46 154.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 ETS87516.1 - 3.6e-42 142.6 0.2 8.6e-42 141.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Myb_DNA-bind_6 PF13921.1 ETS87517.1 - 5.9e-05 23.0 0.2 0.0001 22.3 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 ETS87517.1 - 0.0025 17.8 0.7 0.0063 16.5 0.5 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain HTH_28 PF13518.1 ETS87517.1 - 0.063 13.2 0.3 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.1 ETS87519.1 - 1.3e-25 90.5 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS87519.1 - 8.2e-25 87.6 0.0 1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS87519.1 - 8.9e-10 38.5 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 ETS87519.1 - 0.00059 19.5 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 ETS87519.1 - 0.0034 16.8 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 ETS87519.1 - 0.019 14.0 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1282 PF06930.7 ETS87521.1 - 0.013 15.1 0.1 0.014 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) MscS_TM PF12794.2 ETS87521.1 - 0.077 11.5 0.1 0.091 11.3 0.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sod_Cu PF00080.15 ETS87522.1 - 2.1e-14 53.8 0.3 3.7e-14 53.0 0.2 1.6 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.14 ETS87523.1 - 2.5e-21 75.8 0.0 6.6e-13 48.1 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.13 ETS87524.1 - 5e-08 32.7 8.5 8e-08 32.0 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.10 ETS87525.1 - 0.013 15.6 6.8 0.025 14.8 2.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Trp_Tyr_perm PF03222.8 ETS87525.1 - 0.015 14.1 0.8 0.024 13.4 0.3 1.4 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family Herpes_UL20 PF04544.7 ETS87525.1 - 0.059 13.1 1.5 0.078 12.8 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Flg_bbr_C PF06429.8 ETS87525.1 - 0.14 12.1 0.7 5.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal DUF1469 PF07332.6 ETS87525.1 - 0.21 11.3 1.8 1.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) zf-C2H2 PF00096.21 ETS87526.1 - 8.1e-06 25.8 23.9 0.00087 19.4 0.5 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 ETS87526.1 - 0.0015 18.5 5.5 0.03 14.4 2.9 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 ETS87526.1 - 0.012 15.9 0.3 0.012 15.9 0.2 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS87526.1 - 0.037 13.9 0.2 0.037 13.9 0.1 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger TRP PF06011.7 ETS87527.1 - 1.8e-122 409.0 18.0 2.3e-122 408.7 12.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 ETS87527.1 - 6.3e-39 133.2 7.3 6.3e-39 133.2 5.1 1.7 2 0 0 2 2 2 1 ML-like domain TMEM154 PF15102.1 ETS87527.1 - 0.019 14.7 6.1 1.2 8.8 0.7 2.8 2 0 0 2 2 2 0 TMEM154 protein family RRM_1 PF00076.17 ETS87529.1 - 3.7e-06 26.4 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 ETS87529.1 - 3.8e-05 24.0 13.3 4e-05 23.9 8.1 1.9 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 ETS87529.1 - 0.00036 20.3 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87529.1 - 0.0011 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 ETS87530.1 - 2.1e-17 63.5 3.1 3.1e-17 63.0 1.7 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS87530.1 - 5.3e-10 39.2 1.0 9.6e-10 38.4 0.7 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 ETS87530.1 - 4.3e-05 23.3 0.7 6.7e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 ETS87530.1 - 0.0019 17.9 0.4 0.0053 16.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 ETS87530.1 - 0.044 12.6 0.0 0.19 10.5 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.13 ETS87531.1 - 1.6e-07 31.0 12.9 1.6e-07 31.0 9.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3446 PF11928.3 ETS87531.1 - 0.12 12.6 5.3 2.6 8.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 ETS87531.1 - 2.3 7.6 6.6 0.39 10.1 0.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PAN_1 PF00024.21 ETS87532.1 - 3.8e-05 23.3 2.9 3.8e-05 23.3 2.0 2.5 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 ETS87532.1 - 0.0021 17.7 0.7 0.0048 16.5 0.5 1.6 1 0 0 1 1 1 1 PAN domain Choline_kinase PF01633.15 ETS87533.1 - 1.8e-53 181.2 0.0 2.8e-52 177.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 ETS87533.1 - 2e-08 34.2 0.2 4.4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS87533.1 - 0.00029 20.1 0.0 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 ETS87533.1 - 0.049 12.2 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 ETS87534.1 - 0.0018 18.4 32.9 0.086 13.2 0.0 7.0 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS87534.1 - 0.03 14.2 0.4 0.24 11.3 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS87534.1 - 1.4 9.4 31.7 4.2 7.9 0.0 7.3 7 0 0 7 7 7 0 Zinc finger, C2H2 type CorA PF01544.13 ETS87535.1 - 5.5e-09 35.4 1.6 1.2e-08 34.3 0.7 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.19 ETS87536.1 - 7.9e-10 38.6 0.8 1.5e-09 37.7 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS87536.1 - 5.1e-07 29.7 0.0 6.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS87536.1 - 6.7e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 ETS87536.1 - 6.9e-05 22.9 1.4 0.00012 22.1 1.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS87536.1 - 0.0031 17.6 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS87536.1 - 0.0079 16.0 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS87536.1 - 0.019 14.8 0.2 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 ETS87536.1 - 0.019 14.8 0.3 0.066 13.0 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2190 PF09956.4 ETS87536.1 - 0.088 12.5 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Neur_chan_memb PF02932.11 ETS87537.1 - 0.089 12.6 1.1 0.14 12.0 0.7 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MutS_V PF00488.16 ETS87538.1 - 7.8e-56 189.1 0.1 1.3e-55 188.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 ETS87538.1 - 2.5e-23 82.9 0.8 3.9e-23 82.3 0.1 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 ETS87538.1 - 0.073 13.2 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV MMgT PF10270.4 ETS87539.1 - 4.4e-31 107.4 0.0 5.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF1418 PF07214.7 ETS87539.1 - 0.054 13.1 0.2 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) TolB_N PF04052.8 ETS87540.1 - 0.052 13.6 0.1 0.098 12.7 0.0 1.5 1 1 0 1 1 1 0 TolB amino-terminal domain Clathrin_lg_ch PF01086.12 ETS87540.1 - 3.9 7.3 7.8 13 5.6 5.2 1.8 1 1 0 1 1 1 0 Clathrin light chain AAA PF00004.24 ETS87541.1 - 9.6e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS87541.1 - 3.6e-06 27.1 0.0 0.00059 19.9 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 ETS87541.1 - 2.3e-05 24.1 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 ETS87541.1 - 0.00018 21.4 0.0 0.00071 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 ETS87541.1 - 0.00028 20.9 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 ETS87541.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 ETS87541.1 - 0.0045 17.7 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 ETS87541.1 - 0.0072 16.0 0.1 0.021 14.5 0.1 1.7 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 ETS87541.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 ETS87541.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 ETS87541.1 - 0.02 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS87541.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 ETS87541.1 - 0.041 13.4 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 ETS87541.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 ETS87541.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 ETS87541.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 ETS87541.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 ETS87541.1 - 0.083 11.9 0.1 5.2 6.1 0.0 2.5 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 ETS87541.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 ETS87541.1 - 0.11 12.1 0.3 11 5.6 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 ETS87541.1 - 0.15 11.4 0.2 0.42 9.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 ETS87542.1 - 9e-137 456.6 15.1 1.1e-136 456.2 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 ETS87542.1 - 0.026 13.9 0.0 0.07 12.6 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X DUF3661 PF12400.3 ETS87544.1 - 2.1e-42 144.2 6.1 3.3e-42 143.6 4.2 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein PsbN PF02468.10 ETS87544.1 - 0.041 13.4 0.2 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) RRM_1 PF00076.17 ETS87545.1 - 1.7e-16 59.6 0.1 3.5e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87545.1 - 2.6e-13 49.7 0.0 5.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87545.1 - 5.4e-09 35.7 0.1 9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_S2 PF01601.11 ETS87546.1 - 2.6 6.0 20.1 3.7 5.5 13.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Macoilin PF09726.4 ETS87547.1 - 0.44 8.7 9.8 0.5 8.5 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein RCR PF12273.3 ETS87552.1 - 1.6e-24 86.9 8.4 2.6e-24 86.2 5.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 ETS87552.1 - 0.0076 15.8 1.6 0.0076 15.8 1.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) WBP-1 PF11669.3 ETS87552.1 - 0.018 15.0 0.1 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 PgaD PF13994.1 ETS87552.1 - 0.074 12.5 1.1 0.1 12.0 0.8 1.2 1 0 0 1 1 1 0 PgaD-like protein Hum_adeno_E3A PF05393.6 ETS87552.1 - 0.075 12.7 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Herpes_gE PF02480.11 ETS87552.1 - 0.098 10.9 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RNA_pol_Rpb2_6 PF00562.23 ETS87553.1 - 3.2e-114 381.6 0.1 4.2e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 ETS87553.1 - 2.8e-29 101.5 0.0 4.2e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 ETS87553.1 - 2.6e-25 87.9 0.0 7.1e-25 86.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 ETS87553.1 - 5.3e-24 84.6 0.0 9.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 ETS87553.1 - 8.1e-21 73.7 0.0 2.1e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 ETS87553.1 - 5.3e-15 55.4 0.0 3.9e-14 52.6 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 ETS87553.1 - 0.0021 17.9 0.1 0.0048 16.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 ETS87553.1 - 0.019 14.8 0.7 0.047 13.5 0.5 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 ETS87553.1 - 0.25 11.1 0.8 0.54 10.1 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Tyrosinase PF00264.15 ETS87554.1 - 1.9e-53 181.9 3.2 3.1e-53 181.2 2.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Ammonium_transp PF00909.16 ETS87555.1 - 1.4e-113 379.4 28.8 1.6e-113 379.2 20.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 ETS87556.1 - 2.9e-33 114.2 0.0 6.1e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 ETS87556.1 - 2.5e-21 75.1 0.0 5e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 ETS87556.1 - 2.2e-19 68.7 0.2 5.8e-19 67.3 0.1 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 ETS87556.1 - 1.9e-17 63.2 0.1 5.6e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 ETS87556.1 - 0.0031 17.6 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 ETS87556.1 - 0.013 15.8 0.2 0.031 14.5 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Lum_binding PF00677.12 ETS87557.1 - 6.8e-37 125.2 0.0 3.9e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 ETS87558.1 - 4.3e-31 107.5 0.1 7.4e-31 106.8 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 ETS87558.1 - 7.6e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transferase PF00483.18 ETS87558.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase PadR PF03551.9 ETS87558.1 - 0.045 13.5 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PGM_PMM_I PF02878.11 ETS87559.1 - 8.1e-17 61.0 0.2 1.3e-07 31.1 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 ETS87559.1 - 1.4e-15 57.4 0.5 1.6e-14 54.0 0.0 2.9 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 ETS87559.1 - 2.9e-10 39.9 0.2 9.5e-10 38.3 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 ETS87559.1 - 0.00053 19.9 0.1 0.0023 17.9 0.1 2.2 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CheX PF13690.1 ETS87559.1 - 0.03 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX DUF2392 PF10288.4 ETS87559.1 - 0.14 12.5 0.0 0.44 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Methyltransf_31 PF13847.1 ETS87560.1 - 3.2e-13 49.5 0.1 4.9e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 ETS87560.1 - 2.7e-10 39.8 0.0 4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 ETS87560.1 - 6.5e-09 36.3 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS87560.1 - 1.1e-08 35.1 0.0 2.7e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 ETS87560.1 - 1.3e-08 34.2 0.0 2.9e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 ETS87560.1 - 4.1e-08 33.5 0.0 8.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87560.1 - 2.4e-06 27.8 0.0 7.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 ETS87560.1 - 6.3e-06 25.0 0.1 9.4e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 ETS87560.1 - 5.5e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87560.1 - 0.00019 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS87560.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 ETS87560.1 - 0.0009 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 ETS87560.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 ETS87560.1 - 0.015 14.4 0.2 0.026 13.6 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 ETS87560.1 - 0.044 13.3 0.2 0.064 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 ETS87560.1 - 0.14 11.6 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Per1 PF04080.8 ETS87561.1 - 8.3e-108 359.8 11.7 1e-107 359.5 8.1 1.1 1 0 0 1 1 1 1 Per1-like zf-C2H2 PF00096.21 ETS87562.1 - 0.011 16.0 2.8 0.011 16.0 1.9 3.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS87562.1 - 0.13 12.6 21.2 0.071 13.4 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger HET PF06985.6 ETS87565.1 - 2.5e-25 89.2 0.2 4e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.16 ETS87566.1 - 6.8e-39 132.3 0.0 8e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YchF-GTPase_C PF06071.8 ETS87566.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF933) PMT PF02366.13 ETS87567.1 - 2.6e-79 266.0 16.8 4.2e-79 265.3 11.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 ETS87567.1 - 2.5e-19 69.5 0.4 7.1e-19 68.0 0.1 1.7 1 1 1 2 2 2 2 MIR domain Fascin PF06268.8 ETS87567.1 - 0.13 12.3 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Fascin domain FAA_hydrolase PF01557.13 ETS87568.1 - 1.9e-45 154.9 0.0 2.5e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Borealin PF10512.4 ETS87569.1 - 0.099 12.5 4.6 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 Cell division cycle-associated protein 8 UBA PF00627.26 ETS87569.1 - 0.15 11.9 1.1 1 9.3 1.1 2.2 2 1 0 2 2 2 0 UBA/TS-N domain PWI PF01480.12 ETS87570.1 - 1.7e-27 95.3 0.0 2.7e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 PWI domain NuA4 PF09340.5 ETS87571.1 - 6.3e-22 77.0 0.1 6.3e-22 77.0 0.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4637 PF15470.1 ETS87571.1 - 0.57 9.7 4.5 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Myosin_HC-like PF07058.6 ETS87571.1 - 5.1 6.0 9.1 0.5 9.4 0.1 2.1 1 1 0 2 2 2 0 Myosin II heavy chain-like Peptidase_S9 PF00326.16 ETS87572.1 - 1.8e-56 190.7 0.1 4.3e-56 189.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 ETS87572.1 - 4.1e-12 46.0 0.0 8.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS87572.1 - 6.7e-08 32.6 0.2 1.7e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 ETS87572.1 - 0.0004 18.9 0.1 0.012 14.1 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2721 PF11026.3 ETS87573.1 - 0.0081 15.7 0.1 0.0081 15.7 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2721) MCPsignal PF00015.16 ETS87573.1 - 0.021 14.4 9.7 0.21 11.0 0.8 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IL34 PF15036.1 ETS87573.1 - 0.12 11.8 1.4 0.28 10.7 0.2 2.0 1 1 1 2 2 2 0 Interleukin 34 DUF1664 PF07889.7 ETS87573.1 - 0.41 10.4 11.0 0.079 12.7 1.9 3.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Ammonium_transp PF00909.16 ETS87574.1 - 1.5e-116 389.2 28.9 1.7e-116 389.0 20.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF373 PF04123.8 ETS87574.1 - 0.071 12.1 0.4 0.15 11.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SieB PF14163.1 ETS87574.1 - 0.48 9.9 0.0 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF2207 PF09972.4 ETS87574.1 - 3.6 6.0 7.4 8.9 4.7 0.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CRT10 PF08728.5 ETS87575.1 - 9e-17 60.3 0.0 2.1e-08 32.6 0.0 2.8 3 1 0 3 3 3 2 CRT10 Pkinase PF00069.20 ETS87576.1 - 0.0053 15.9 0.0 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Zn_clus PF00172.13 ETS87577.1 - 0.067 13.1 6.0 0.14 12.1 4.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EcsB PF05975.7 ETS87577.1 - 0.2 10.0 0.1 0.29 9.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB TauD PF02668.11 ETS87578.1 - 3.8e-21 75.9 0.3 5e-21 75.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 ETS87578.1 - 0.016 14.1 0.1 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 CsiD MCLC PF05934.6 ETS87580.1 - 0.0091 14.3 2.7 0.021 13.1 1.9 1.5 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) SOG2 PF10428.4 ETS87581.1 - 0.19 10.3 19.0 0.23 10.1 13.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Rifin_STEVOR PF02009.11 ETS87581.1 - 5.5 6.5 7.4 6.5 6.3 5.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF3144 PF11342.3 ETS87583.1 - 0.004 17.1 1.2 0.015 15.3 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3144) DUF1771 PF08590.5 ETS87584.1 - 1.3e-13 50.7 10.9 2.7e-13 49.6 7.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 ETS87584.1 - 2.4e-10 40.4 0.0 8e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 ETS87584.1 - 2.8e-06 26.8 1.6 0.0077 15.8 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 ETS87584.1 - 0.014 15.4 0.3 0.039 14.0 0.0 1.8 2 0 0 2 2 2 0 HBS1 N-terminus Cupin_8 PF13621.1 ETS87585.1 - 1e-17 64.4 0.0 9.1e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 ETS87585.1 - 8.5e-11 42.1 0.0 2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 ETS87585.1 - 1.5e-07 30.9 0.1 7.2e-06 25.6 0.1 2.8 3 0 0 3 3 3 1 F-box-like Cupin_4 PF08007.7 ETS87585.1 - 7.9e-05 22.0 0.0 0.00018 20.8 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein F-box PF00646.28 ETS87585.1 - 0.0017 17.9 0.1 0.0048 16.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 ETS87585.1 - 0.057 13.8 0.3 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DEAD PF00270.24 ETS87586.1 - 4.3e-44 149.9 1.9 6.1e-44 149.4 0.8 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87586.1 - 1.1e-27 95.7 0.2 6.2e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS87586.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 ETS87586.1 - 0.0055 16.3 0.1 0.017 14.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 ETS87586.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 ETS87586.1 - 0.025 14.7 0.2 0.11 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 ETS87586.1 - 0.029 14.0 0.1 0.099 12.4 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 ETS87586.1 - 0.074 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 ETS87586.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein tRNA-synt_1 PF00133.17 ETS87587.1 - 5.4e-218 724.8 0.2 5.4e-218 724.8 0.2 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 ETS87587.1 - 3.2e-37 127.6 0.5 8.8e-37 126.2 0.3 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 ETS87587.1 - 1.8e-14 53.2 0.2 0.00011 20.9 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 ETS87587.1 - 4.3e-10 39.1 0.2 4.8e-09 35.7 0.0 3.7 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 ETS87587.1 - 0.0022 18.0 5.4 0.0022 18.0 3.7 3.6 4 0 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm Fusion_gly PF00523.13 ETS87587.1 - 0.028 12.5 0.2 0.049 11.6 0.2 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 EMP24_GP25L PF01105.19 ETS87587.1 - 0.059 13.0 0.3 0.18 11.5 0.2 1.8 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OmpH PF03938.9 ETS87587.1 - 2.2 8.1 21.2 0.039 13.8 1.0 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Metallophos PF00149.23 ETS87588.1 - 5.1e-06 26.0 2.2 1.2e-05 24.7 1.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nop14 PF04147.7 ETS87588.1 - 7.2e-05 20.9 20.4 7.2e-05 20.9 14.2 1.5 2 0 0 2 2 2 1 Nop14-like family YL1 PF05764.8 ETS87588.1 - 0.006 16.2 24.3 0.006 16.2 16.9 3.3 3 0 0 3 3 3 1 YL1 nuclear protein CDC45 PF02724.9 ETS87588.1 - 0.016 13.2 15.7 0.035 12.1 10.9 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 ETS87588.1 - 0.019 13.7 25.5 0.049 12.3 17.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glypican PF01153.14 ETS87588.1 - 0.36 9.3 4.5 0.57 8.7 3.1 1.2 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 ETS87588.1 - 0.76 8.1 19.7 1.7 6.9 13.7 1.5 1 0 0 1 1 1 0 Daxx Family Suf PF05843.9 ETS87588.1 - 1.5 8.4 5.7 0.37 10.4 1.2 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CobT PF06213.7 ETS87588.1 - 3.9 6.5 19.0 7.7 5.5 13.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT His_Phos_1 PF00300.17 ETS87589.1 - 2.1e-08 34.3 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Stk19 PF10494.4 ETS87590.1 - 2.4e-62 210.6 0.0 2.8e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Kinesin PF00225.18 ETS87591.1 - 8.2e-97 323.9 0.1 8.2e-97 323.9 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Spore_coat_CotO PF14153.1 ETS87591.1 - 0.63 9.4 7.7 1.8 7.9 5.4 1.7 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 ETS87591.1 - 9.1 6.2 15.2 1.1 9.2 4.5 3.0 2 1 1 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Cytochrom_NNT PF03264.9 ETS87592.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region CAAD PF14159.1 ETS87592.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SH3BGR PF04908.10 ETS87593.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein SNARE_assoc PF09335.6 ETS87594.1 - 2.3e-13 50.4 7.5 2.3e-13 50.4 5.2 2.4 2 1 2 4 4 4 1 SNARE associated Golgi protein DUF202 PF02656.10 ETS87594.1 - 0.0077 16.4 0.2 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HAMP PF00672.20 ETS87594.1 - 3.5 7.8 6.9 11 6.2 0.0 3.4 3 0 0 3 3 3 0 HAMP domain Abhydrolase_6 PF12697.2 ETS87595.1 - 2.5e-34 119.1 1.6 3.3e-34 118.7 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS87595.1 - 2.8e-14 53.0 0.0 5.9e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87595.1 - 2e-09 37.3 0.4 1.6e-07 31.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 ETS87595.1 - 3.1e-05 23.7 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase p450 PF00067.17 ETS87597.1 - 2.8e-73 247.0 0.0 3.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3074 PF11274.3 ETS87598.1 - 9.9e-37 126.3 0.0 1.3e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ofd1_CTDD PF10637.4 ETS87599.1 - 2.3e-102 341.6 0.0 6.9e-94 313.9 0.1 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 ETS87599.1 - 2.9e-15 56.5 0.0 9.1e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 ETS87599.1 - 0.02 14.5 0.0 0.062 12.9 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 ETS87600.1 - 2.2e-61 207.6 0.0 3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 ETS87600.1 - 1.2e-05 23.8 0.0 1.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 ETS87600.1 - 0.0023 16.9 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 ETS87600.1 - 0.048 12.6 0.0 0.099 11.6 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribul_P_3_epim PF00834.14 ETS87601.1 - 4.2e-65 218.6 0.0 2e-64 216.4 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 ETS87601.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 ETS87601.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.14 ETS87601.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain eIF-3_zeta PF05091.7 ETS87602.1 - 4.7e-199 662.3 0.0 5.5e-199 662.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 ETS87602.1 - 0.01 15.2 0.1 0.032 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF569) CDC48_2 PF02933.12 ETS87602.1 - 0.039 13.6 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 PAP1 PF08601.5 ETS87603.1 - 0.00018 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 ETS87604.1 - 0.0011 18.8 10.4 0.0029 17.5 7.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor DUF2205 PF10224.4 ETS87604.1 - 0.017 14.6 1.7 0.029 13.9 1.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 ETS87604.1 - 0.042 14.1 1.2 0.042 14.1 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TSC22 PF01166.13 ETS87604.1 - 0.096 12.6 0.5 0.19 11.7 0.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.10 ETS87604.1 - 1.4 8.8 11.9 11 5.9 8.2 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Pol_alpha_B_N PF08418.5 ETS87604.1 - 1.4 8.3 11.2 1.8 8.0 7.4 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Acyltransferase PF01553.16 ETS87605.1 - 5.4e-13 48.5 0.0 7.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NUFIP1 PF10453.4 ETS87605.1 - 0.0035 16.8 0.4 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Pkinase PF00069.20 ETS87606.1 - 5.9e-61 205.8 0.0 2.6e-39 134.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87606.1 - 3.3e-27 95.2 0.0 4.9e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 ETS87606.1 - 1.4e-12 47.6 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 ETS87606.1 - 6.5e-08 31.8 0.0 6e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 ETS87606.1 - 2.4e-06 27.4 0.2 0.0028 17.4 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family PAS PF00989.19 ETS87606.1 - 0.011 15.5 0.0 0.041 13.6 0.0 2.0 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 ETS87606.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 ETS87606.1 - 0.02 15.2 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.6 ETS87606.1 - 0.023 13.5 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.19 ETS87606.1 - 0.11 13.0 2.4 1.1 9.8 0.0 3.9 3 0 0 3 3 3 0 Protein kinase C terminal domain HLH PF00010.21 ETS87607.1 - 1.8e-17 62.7 0.3 4e-17 61.6 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 ETS87607.1 - 0.086 12.4 6.0 0.35 10.4 1.0 2.5 2 0 0 2 2 2 0 IncA protein DUF904 PF06005.7 ETS87607.1 - 2.2 8.6 11.9 0.38 11.0 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) MSC PF09402.5 ETS87608.1 - 3.2e-102 341.6 0.0 4.5e-102 341.2 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 ETS87608.1 - 3.5e-16 58.4 0.0 6.5e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 ETS87608.1 - 0.0017 18.3 0.5 3.2 7.8 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3350) Thymopoietin PF08198.6 ETS87608.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Thymopoietin protein Endonuc-dimeris PF09124.5 ETS87608.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Rifin_STEVOR PF02009.11 ETS87609.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 ETS87609.1 - 0.016 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family TrbL PF04610.9 ETS87609.1 - 8.1 6.0 7.7 2.6 7.7 3.0 1.8 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein TAP_C PF03943.8 ETS87610.1 - 9.5e-13 47.3 0.2 2.3e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 ETS87610.1 - 0.00021 20.8 4.3 0.0052 16.3 2.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 ETS87610.1 - 0.0032 17.8 0.8 0.049 13.9 0.6 2.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 ETS87610.1 - 0.042 13.3 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain LRR_6 PF13516.1 ETS87610.1 - 0.12 12.5 1.5 10 6.5 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeat ResIII PF04851.10 ETS87611.1 - 3.7e-22 79.0 0.0 8.5e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 ETS87611.1 - 6.3e-22 77.8 0.0 7.2e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87611.1 - 3.3e-20 71.7 0.2 1.1e-19 69.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 ETS87611.1 - 0.0003 20.9 0.0 0.0012 19.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2002 PF09400.5 ETS87611.1 - 0.13 12.0 0.1 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) RNB PF00773.14 ETS87613.1 - 1.8e-57 195.0 0.0 3.1e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain Glyco_hydro_17 PF00332.13 ETS87615.1 - 0.012 14.7 0.1 0.063 12.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 WD40 PF00400.27 ETS87616.1 - 9.3e-09 34.8 0.0 1.1e-07 31.4 0.1 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 ETS87616.1 - 0.14 11.8 0.0 0.43 10.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.10 ETS87618.1 - 1.1e-291 967.8 0.8 1.4e-291 967.5 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 ETS87618.1 - 1.9e-16 60.3 0.9 7.2e-16 58.4 0.6 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 ETS87618.1 - 3.9e-14 52.9 0.1 3.9e-12 46.4 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 ETS87618.1 - 7.2e-10 38.5 0.1 6.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 ETS87618.1 - 0.00011 21.6 0.1 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 ETS87618.1 - 0.032 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sel1 PF08238.7 ETS87619.1 - 1.6e-38 130.2 28.3 4.9e-06 27.0 0.2 7.5 6 1 1 7 7 7 7 Sel1 repeat Pkinase PF00069.20 ETS87620.1 - 1.4e-65 221.0 0.0 2e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87620.1 - 5.7e-42 143.5 0.1 9.1e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 ETS87620.1 - 6e-08 32.5 0.2 0.00016 21.5 0.0 2.9 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 ETS87620.1 - 1.1e-07 31.1 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 ETS87620.1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 ETS87621.1 - 5.9e-38 129.6 1.1 9e-38 129.0 0.8 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med21 PF11221.3 ETS87621.1 - 0.007 16.3 2.4 0.007 16.3 1.7 2.0 2 0 0 2 2 2 1 Subunit 21 of Mediator complex BBP1_C PF15272.1 ETS87621.1 - 0.033 13.7 0.3 0.033 13.7 0.2 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4140 PF13600.1 ETS87621.1 - 0.098 13.1 0.2 0.098 13.1 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TAF4 PF05236.9 ETS87621.1 - 1.5 8.0 10.5 0.061 12.5 0.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CAF-1_p150 PF11600.3 ETS87621.1 - 8.1 5.7 19.0 7.7 5.8 4.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SBDS PF01172.13 ETS87623.1 - 2e-27 94.8 0.4 2.5e-27 94.5 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NB-ARC PF00931.17 ETS87623.1 - 0.053 12.3 0.1 0.099 11.4 0.0 1.5 1 1 1 2 2 2 0 NB-ARC domain RhoGEF PF00621.15 ETS87624.1 - 5.6e-24 85.0 0.0 9.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 ETS87624.1 - 0.065 13.4 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 PH domain Activin_recp PF01064.18 ETS87624.1 - 0.11 13.1 0.8 0.27 11.8 0.0 2.0 2 1 0 2 2 2 0 Activin types I and II receptor domain GRASP55_65 PF04495.9 ETS87625.1 - 4.4e-05 23.4 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 ETS87625.1 - 4.9e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 ETS87625.1 - 0.00044 20.3 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 ETS87626.1 - 3.6e-49 166.2 0.0 4.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 ETS87626.1 - 1.7e-15 57.5 0.0 3.5e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 ETS87626.1 - 7.5e-11 41.5 0.0 9.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 ETS87626.1 - 0.00037 20.6 0.1 0.0031 17.6 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 ETS87626.1 - 0.0023 17.1 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 ETS87626.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 ETS87626.1 - 0.021 13.5 2.6 0.41 9.2 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 ETS87626.1 - 0.046 13.8 0.3 0.25 11.4 0.1 2.1 2 1 0 3 3 3 0 AAA domain SRPRB PF09439.5 ETS87626.1 - 0.051 12.7 0.0 0.089 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 ETS87626.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS87626.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Septin PF00735.13 ETS87626.1 - 0.22 10.4 0.9 0.28 10.1 0.1 1.5 2 0 0 2 2 2 0 Septin E1-E2_ATPase PF00122.15 ETS87627.1 - 1.1e-63 214.3 6.7 2.5e-63 213.1 3.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS87627.1 - 2.8e-46 157.3 6.9 2.8e-46 157.3 4.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS87627.1 - 1.5e-31 110.4 0.0 1.5e-30 107.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS87627.1 - 3.1e-23 81.5 0.0 6.1e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 ETS87627.1 - 2.2e-19 68.6 0.0 6.1e-19 67.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS87627.1 - 8e-17 62.0 0.0 3e-16 60.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS87627.1 - 1.4e-08 34.6 1.1 3.3e-06 26.8 0.7 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 ETS87627.1 - 0.015 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 ETS87628.1 - 1.8e-35 121.9 0.0 2e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 ETS87629.1 - 4.4e-24 84.1 0.1 8.3e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Rad60-SLD PF11976.3 ETS87629.1 - 1.4e-05 24.7 0.1 9.9e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.18 ETS87629.1 - 0.00021 21.7 0.1 0.00079 19.8 0.2 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain RBD PF02196.10 ETS87629.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain DUF4205 PF13898.1 ETS87629.1 - 0.086 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) FERM_N PF09379.5 ETS87629.1 - 0.088 12.8 0.0 0.42 10.7 0.0 2.4 1 1 0 1 1 1 0 FERM N-terminal domain Lipase_3 PF01764.20 ETS87631.1 - 1.1e-31 109.3 0.0 1.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 ETS87631.1 - 0.00033 20.4 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 ETS87631.1 - 0.00063 19.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 ETS87631.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 ETS87631.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein 14-3-3 PF00244.15 ETS87632.1 - 2.5e-106 354.0 0.9 3.1e-106 353.7 0.6 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.14 ETS87632.1 - 0.2 12.0 11.7 0.21 11.9 4.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF3_subunit PF08597.5 ETS87633.1 - 0.093 12.2 1.2 0.17 11.3 0.8 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Syja_N PF02383.13 ETS87634.1 - 1.6e-86 289.9 0.0 2.7e-86 289.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 ETS87634.1 - 1.8e-23 83.7 0.0 3.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_16 PF13432.1 ETS87635.1 - 6.5e-06 26.6 0.0 0.00042 20.9 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.9 ETS87635.1 - 3.6e-05 23.6 6.0 0.021 14.5 0.0 3.2 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 ETS87635.1 - 0.00086 19.7 6.0 1.3 9.8 0.0 5.6 6 1 1 7 7 7 2 Tetratricopeptide repeat peroxidase PF00141.18 ETS87636.1 - 3.9e-50 170.4 0.0 8e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 Peroxidase zf-LYAR PF08790.6 ETS87637.1 - 7.2e-08 31.9 0.6 1.6e-07 30.8 0.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Abhydrolase_5 PF12695.2 ETS87638.1 - 2.9e-22 78.9 0.0 4.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 ETS87638.1 - 4.9e-16 59.2 0.0 3.6e-14 53.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS87638.1 - 6.7e-07 29.0 0.0 0.00064 19.3 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF818 PF05677.7 ETS87638.1 - 7.4e-06 24.9 0.1 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.7 ETS87638.1 - 9.1e-06 24.3 0.1 0.0066 14.9 0.1 2.8 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 ETS87638.1 - 9.4e-05 21.9 0.0 0.12 11.7 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 ETS87638.1 - 9.4e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 ETS87638.1 - 0.00014 21.2 0.0 0.0023 17.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 ETS87638.1 - 0.00022 20.7 0.0 0.00058 19.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.13 ETS87638.1 - 0.00058 19.2 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 ETS87638.1 - 0.00083 19.1 0.0 0.048 13.3 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 ETS87638.1 - 0.017 14.7 0.4 0.079 12.5 0.2 2.0 1 1 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 ETS87638.1 - 0.022 13.0 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.3 ETS87638.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 ETS87638.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.7 ETS87638.1 - 0.14 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S15 PF02129.13 ETS87638.1 - 0.16 11.3 0.0 1.7 7.9 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) R3H PF01424.17 ETS87639.1 - 5.4e-13 48.4 0.1 1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-RING_2 PF13639.1 ETS87641.1 - 4.1e-05 23.3 5.1 6.3e-05 22.7 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 ETS87641.1 - 0.00036 20.1 7.6 0.00058 19.4 5.3 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 ETS87641.1 - 0.00036 20.1 3.9 0.003 17.2 1.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 ETS87641.1 - 0.037 14.0 6.5 0.07 13.1 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 ETS87641.1 - 0.069 12.8 7.5 0.045 13.4 2.7 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 ETS87641.1 - 0.093 12.8 4.3 0.16 12.0 3.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 ETS87641.1 - 0.095 12.6 5.3 0.16 11.9 3.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Rep_fac-A_C PF08646.5 ETS87641.1 - 0.11 12.2 3.4 0.1 12.2 1.3 1.6 1 1 1 2 2 2 0 Replication factor-A C terminal domain RINGv PF12906.2 ETS87641.1 - 0.29 11.1 9.1 0.48 10.4 6.3 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Sec23_Sec24 PF04810.10 ETS87641.1 - 1.8 8.1 8.0 30 4.2 0.0 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DUF2175 PF09943.4 ETS87641.1 - 5.1 7.1 6.7 3.1 7.9 3.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-MIZ PF02891.15 ETS87641.1 - 6.2 6.4 12.2 0.61 9.6 0.3 2.6 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger WSC PF01822.14 ETS87642.1 - 1.5e-83 274.7 101.8 7.1e-19 67.5 12.1 6.1 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.6 ETS87642.1 - 4.6e-25 88.1 0.0 5.6e-24 84.5 0.0 2.7 4 0 0 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 ETS87642.1 - 1e-21 76.8 0.0 4e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF221 PF02714.10 ETS87643.1 - 5.5e-93 311.3 16.5 8.4e-93 310.7 11.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 ETS87643.1 - 5.9e-42 142.8 1.1 5.9e-42 142.8 0.8 2.7 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 ETS87643.1 - 8.9e-17 61.3 0.1 2.1e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2244 PF10003.4 ETS87643.1 - 0.014 14.7 2.6 1.8 7.9 0.0 2.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Glyco_hydro_6 PF01341.12 ETS87644.1 - 8.5e-96 320.8 1.1 1.1e-95 320.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SLD3 PF08639.5 ETS87645.1 - 1.4e-107 360.3 12.1 1.4e-107 360.3 8.4 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 Pkinase PF00069.20 ETS87646.1 - 2.9e-67 226.5 0.0 4.9e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87646.1 - 7e-37 126.8 0.0 1.3e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS87646.1 - 4.2e-08 32.5 0.0 7.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 ETS87646.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS87646.1 - 0.05 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HCV_NS1 PF01560.12 ETS87646.1 - 0.24 9.8 0.0 0.37 9.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 GN3L_Grn1 PF08701.6 ETS87647.1 - 5.1e-26 90.3 17.1 1.2e-25 89.2 11.8 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 ETS87647.1 - 3e-19 69.0 0.0 3e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 ETS87647.1 - 4.5e-06 26.5 3.7 0.19 11.5 0.1 3.9 4 0 0 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 ETS87647.1 - 8.7e-06 25.2 0.0 0.09 12.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PGA2 PF07543.7 ETS87647.1 - 1.8e-05 24.5 8.6 1.8e-05 24.5 6.0 2.3 2 0 0 2 2 2 1 Protein trafficking PGA2 cobW PF02492.14 ETS87647.1 - 0.00013 21.5 0.0 0.13 11.7 0.0 2.9 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 ETS87647.1 - 0.00026 20.2 0.1 0.00044 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 ETS87647.1 - 0.0005 19.3 0.1 0.0085 15.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 ETS87647.1 - 0.0074 16.7 0.1 1.5 9.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 ETS87647.1 - 0.014 15.3 0.3 0.014 15.3 0.2 2.3 3 0 0 3 3 3 0 AAA ATPase domain ArgK PF03308.11 ETS87647.1 - 0.017 13.9 0.1 0.017 13.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 ETS87647.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 ETS87647.1 - 0.61 10.9 0.0 0.61 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.1 ETS87648.1 - 2e-16 60.7 0.0 2.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 ETS87648.1 - 2.9e-09 37.6 0.0 7.1e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 ETS87648.1 - 1.2e-08 34.4 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 ETS87648.1 - 0.0028 17.8 0.0 0.0074 16.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 ETS87648.1 - 0.079 12.8 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 ETS87648.1 - 0.083 12.9 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Homeobox PF00046.24 ETS87649.1 - 1.9e-16 59.3 1.1 4e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ETS87649.1 - 3.5e-06 26.5 0.2 9e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HMG14_17 PF01101.13 ETS87649.1 - 0.043 14.4 5.3 0.11 13.2 3.7 1.8 1 1 0 1 1 1 0 HMG14 and HMG17 COesterase PF00135.23 ETS87650.1 - 7.8e-95 318.5 0.0 1.1e-94 318.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS87650.1 - 2.1e-06 27.4 0.1 1.5e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold HLH PF00010.21 ETS87651.1 - 7.8e-13 47.9 0.2 1.8e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HlyIII PF03006.15 ETS87653.1 - 0.16 11.3 4.2 0.29 10.5 3.0 1.5 1 1 0 1 1 1 0 Haemolysin-III related Med16 PF11635.3 ETS87654.1 - 4.6e-100 335.7 1.0 6.2e-100 335.2 0.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3819 PF12842.2 ETS87654.1 - 0.091 12.4 0.2 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) SIR2 PF02146.12 ETS87655.1 - 3.7e-28 98.4 0.1 4.6e-27 94.8 0.1 2.1 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.18 ETS87656.1 - 5.5e-66 222.3 0.0 1.1e-65 221.3 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 ETS87656.1 - 3.4e-21 74.6 10.5 1.3e-14 53.5 0.3 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 ETS87656.1 - 1.6e-13 50.2 0.0 5.1e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FF PF01846.14 ETS87657.1 - 7.6e-52 173.0 10.3 2.7e-13 49.6 0.1 7.0 6 0 0 6 6 6 6 FF domain WW PF00397.21 ETS87657.1 - 1.5e-17 63.0 16.8 1.3e-10 40.9 2.1 2.9 3 0 0 3 3 3 2 WW domain Trs65 PF12735.2 ETS87658.1 - 6.3e-74 249.0 0.0 1.1e-73 248.2 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 E1-E2_ATPase PF00122.15 ETS87660.1 - 4.4e-64 215.6 3.3 8.8e-64 214.6 2.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 ETS87660.1 - 5.8e-32 110.6 5.0 5.8e-32 110.6 3.5 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 ETS87660.1 - 6.6e-27 95.3 0.0 1.1e-25 91.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 ETS87660.1 - 4.8e-22 77.7 0.0 1.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 ETS87660.1 - 1.3e-17 62.9 0.0 6.6e-17 60.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 ETS87660.1 - 2.8e-11 43.9 0.1 6.3e-11 42.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 ETS87660.1 - 3.8e-07 29.9 0.5 1.1e-05 25.2 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PrpF PF04303.8 ETS87661.1 - 3e-96 322.4 0.9 3.8e-96 322.0 0.6 1.1 1 0 0 1 1 1 1 PrpF protein Acyl_transf_3 PF01757.17 ETS87662.1 - 0.013 14.3 0.9 0.016 14.0 0.6 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF2955 PF11168.3 ETS87662.1 - 0.053 13.1 4.0 0.08 12.6 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2955) Herpes_LAMP2 PF06126.6 ETS87662.1 - 0.1 11.0 0.3 0.11 10.9 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Fungal_trans_2 PF11951.3 ETS87663.1 - 1.6e-20 73.0 2.3 5.7e-20 71.2 1.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 ETS87664.1 - 1.4e-164 547.7 0.0 1.8e-164 547.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS87664.1 - 4.3e-18 65.2 0.3 1e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 ETS87664.1 - 3.1e-14 52.7 0.0 6.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MFS_1 PF07690.11 ETS87665.1 - 2.7e-30 105.2 9.2 2.7e-30 105.2 6.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Tetraspannin PF00335.15 ETS87665.1 - 0.43 9.8 0.0 0.43 9.8 0.0 3.8 4 1 0 4 4 4 0 Tetraspanin family Amidohydro_3 PF07969.6 ETS87666.1 - 2.4e-59 201.6 1.2 2.8e-59 201.3 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 ETS87666.1 - 9.6e-11 41.8 0.9 2.3e-06 27.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 ETS87666.1 - 5.6e-08 32.4 0.1 1.9e-07 30.7 0.1 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 ETS87666.1 - 1.4e-06 28.5 6.0 0.00067 19.7 0.1 3.0 3 1 1 4 4 4 2 Amidohydrolase Asp PF00026.18 ETS87667.1 - 2.1e-38 132.3 1.0 2.8e-38 131.9 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 ETS87667.1 - 4e-07 30.1 1.4 9.9e-07 28.8 0.4 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 ETS87667.1 - 0.12 12.9 0.2 29 5.2 0.1 3.1 2 1 0 2 2 2 0 Aspartyl protease Acetyltransf_3 PF13302.1 ETS87668.1 - 1.4e-36 125.7 0.0 1.6e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS87668.1 - 5.2e-07 29.6 0.1 7.4e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS87668.1 - 9.3e-07 28.9 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS87668.1 - 1.3e-05 25.0 0.0 2.1e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 ETS87668.1 - 0.0054 16.8 0.0 0.0077 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GST_C_3 PF14497.1 ETS87669.1 - 4.8e-11 43.0 0.0 7.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS87669.1 - 6.8e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 ETS87669.1 - 2.1e-05 24.4 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS87669.1 - 0.00038 20.5 0.0 0.0018 18.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 ETS87669.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Xpo1 PF08389.7 ETS87669.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Exportin 1-like protein RRM_1 PF00076.17 ETS87670.1 - 6.4e-13 48.1 0.0 7.8e-05 22.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87670.1 - 3.7e-12 46.0 0.0 5.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87670.1 - 9.8e-05 22.1 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 ETS87670.1 - 3.1 8.1 9.0 0.18 12.1 0.5 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pex14_N PF04695.8 ETS87670.1 - 5.8 6.9 7.7 1.1 9.3 0.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3405 PF11885.3 ETS87672.1 - 9.4e-206 683.8 3.1 1.1e-205 683.5 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LRR_9 PF14580.1 ETS87672.1 - 0.27 10.7 0.0 0.5 9.9 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat EMP24_GP25L PF01105.19 ETS87673.1 - 9.2e-45 152.5 0.1 1.1e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 ETS87673.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase Arf PF00025.16 ETS87674.1 - 8.4e-80 266.0 0.3 9.7e-80 265.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 ETS87674.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 ETS87674.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 ETS87674.1 - 1.8e-12 46.6 1.8 2.3e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 ETS87674.1 - 3.7e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 ETS87674.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 ETS87674.1 - 2.5e-06 27.4 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 ETS87674.1 - 0.0089 15.1 0.7 0.02 13.9 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 ETS87674.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 ETS87674.1 - 0.039 13.8 0.2 0.095 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain GCV_T PF01571.16 ETS87675.1 - 9.3e-65 217.9 0.0 1.3e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 ETS87675.1 - 4.3e-25 87.5 0.7 8.7e-25 86.5 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 ETS87675.1 - 0.035 14.0 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus DUF3659 PF12396.3 ETS87675.1 - 0.043 13.5 0.2 0.094 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) V-SNARE_C PF12352.3 ETS87676.1 - 7.3e-14 51.5 0.4 7.3e-14 51.5 0.3 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.15 ETS87676.1 - 0.098 12.3 4.1 0.96 9.1 0.4 2.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain Not3 PF04065.10 ETS87676.1 - 0.21 10.8 2.9 0.3 10.3 0.9 1.8 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF3683 PF12447.3 ETS87676.1 - 0.8 9.5 4.2 4.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) YgaB PF14182.1 ETS87676.1 - 2.1 8.6 5.4 1.6 9.0 0.4 2.8 3 1 1 4 4 4 0 YgaB-like protein Atg14 PF10186.4 ETS87676.1 - 2.5 6.9 8.9 0.57 9.0 4.2 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 ETS87676.1 - 5.2 7.0 9.5 1.1 9.2 2.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Ribosomal_L29 PF00831.18 ETS87677.1 - 2.6e-18 65.4 3.9 1.5e-17 62.9 0.8 2.4 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 ETS87677.1 - 0.084 13.1 1.5 0.11 12.7 1.1 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF2450 PF10475.4 ETS87677.1 - 0.12 11.2 1.3 0.14 11.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) zf-H2C2_2 PF13465.1 ETS87678.1 - 2.7e-26 90.5 33.0 3.8e-08 33.2 0.3 6.6 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 ETS87678.1 - 3.4e-22 77.3 37.3 0.00023 21.3 1.0 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS87678.1 - 1.2e-14 53.4 34.7 0.031 14.5 0.3 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 ETS87678.1 - 2.9e-09 36.5 26.0 0.0034 17.2 0.2 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 ETS87678.1 - 0.0006 19.9 15.6 0.014 15.5 0.3 5.2 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS87678.1 - 0.012 15.7 27.0 0.095 12.8 0.1 6.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Arc_trans_TRASH PF08394.5 ETS87678.1 - 0.023 14.8 0.7 0.023 14.8 0.5 3.5 4 0 0 4 4 4 0 Archaeal TRASH domain BolA PF01722.13 ETS87678.1 - 0.7 9.8 3.5 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 BolA-like protein Pkinase PF00069.20 ETS87679.1 - 8.7e-62 208.6 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87679.1 - 1.8e-28 99.3 0.0 3.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 ETS87679.1 - 1.6e-08 34.5 0.6 8.5e-08 32.2 0.2 2.3 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 ETS87679.1 - 0.0065 15.4 0.0 0.017 14.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 ETS87679.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 ETS87679.1 - 0.092 12.0 0.3 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 RIO1 family PQ-loop PF04193.9 ETS87681.1 - 1.5e-27 94.8 0.3 8.2e-18 63.7 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat Zn_clus PF00172.13 ETS87682.1 - 0.065 13.1 14.5 0.14 12.1 10.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IcmL PF11393.3 ETS87682.1 - 0.15 11.9 0.3 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein Ppx-GppA PF02541.11 ETS87683.1 - 5e-35 121.0 0.0 8.2e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family O-FucT PF10250.4 ETS87684.1 - 1.1e-08 34.6 0.0 4.7e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CENP-B_dimeris PF09026.5 ETS87686.1 - 0.036 14.2 1.1 0.036 14.2 0.7 2.6 2 1 1 3 3 3 0 Centromere protein B dimerisation domain BTB PF00651.26 ETS87686.1 - 0.063 13.2 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Nucleoplasmin PF03066.10 ETS87686.1 - 0.93 9.0 4.8 0.39 10.2 1.5 1.7 2 0 0 2 2 2 0 Nucleoplasmin Oxidored_FMN PF00724.15 ETS87687.1 - 1.1e-75 254.8 0.0 1.1e-72 244.8 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C15 PF01470.12 ETS87689.1 - 0.00036 20.4 0.0 0.0021 17.9 0.0 1.9 1 1 0 1 1 1 1 Pyroglutamyl peptidase HhH-GPD PF00730.20 ETS87691.1 - 4.8e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein BAF1_ABF1 PF04684.8 ETS87691.1 - 1.5 7.6 23.7 3.8 6.2 16.4 1.7 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cytochrom_C1 PF02167.10 ETS87692.1 - 6.9e-82 274.3 0.0 8.4e-82 274.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 ETS87692.1 - 0.0043 17.1 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 ETS87692.1 - 0.025 15.3 0.0 0.099 13.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c DAHP_synth_1 PF00793.15 ETS87693.1 - 6.8e-98 326.6 0.0 8.5e-98 326.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COBRA1 PF06209.8 ETS87693.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) DUF2029 PF09594.5 ETS87695.1 - 0.0048 16.4 0.7 0.0048 16.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) Transferase PF02458.10 ETS87696.1 - 6.5e-16 57.8 0.0 8.7e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_3 PF01494.14 ETS87697.1 - 6.4e-21 74.7 0.1 1.7e-20 73.3 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 ETS87697.1 - 0.0087 15.1 0.4 0.13 11.3 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 ETS87697.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 ETS87697.1 - 0.025 13.2 0.2 0.083 11.5 0.0 1.7 1 1 1 2 2 2 0 Tryptophan halogenase DAO PF01266.19 ETS87697.1 - 0.041 12.7 0.1 4 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 ETS87697.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Far-17a_AIG1 PF04750.9 ETS87698.1 - 2.6e-55 186.7 3.9 3e-55 186.5 2.7 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein p450 PF00067.17 ETS87699.1 - 1.8e-78 264.1 0.0 3.2e-78 263.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3640 PF12342.3 ETS87699.1 - 0.14 11.7 0.2 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) DUF1932 PF09130.6 ETS87700.1 - 1.4e-17 63.1 1.0 2.9e-17 62.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 ETS87700.1 - 5.3e-08 33.1 0.2 1.5e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 ETS87700.1 - 6.3e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 ETS87700.1 - 0.00052 20.0 1.4 0.034 14.1 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding 3HCDH_N PF02737.13 ETS87700.1 - 0.0057 16.3 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 ETS87700.1 - 0.013 14.6 0.1 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.10 ETS87700.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Sugar_tr PF00083.19 ETS87701.1 - 3.6e-31 108.2 26.1 1.6e-20 73.1 4.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 ETS87701.1 - 6.8e-25 87.5 18.8 3.4e-18 65.4 7.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 ETS87701.1 - 0.0019 16.6 5.5 0.0019 16.6 3.8 2.4 2 1 1 3 3 3 3 MFS/sugar transport protein DUF2238 PF09997.4 ETS87701.1 - 5.5 6.3 10.3 2.8 7.3 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Acetate_kinase PF00871.12 ETS87703.1 - 2.9e-94 315.7 0.0 3.6e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family zf-C2H2_4 PF13894.1 ETS87704.1 - 1.2e-05 25.2 9.0 0.00063 19.8 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 ETS87704.1 - 0.00015 21.9 11.6 0.004 17.4 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS87704.1 - 0.0018 18.4 2.7 0.0018 18.4 1.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.7 ETS87704.1 - 0.0087 16.4 0.9 0.016 15.6 0.3 1.7 1 1 0 1 1 1 1 Integrin beta tail domain zf-met PF12874.2 ETS87704.1 - 0.099 12.8 6.8 1.3 9.2 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FAM217 PF15344.1 ETS87704.1 - 1.5 8.2 11.7 2.6 7.5 8.1 1.4 1 0 0 1 1 1 0 FAM217 family zf-TRAF PF02176.13 ETS87704.1 - 2.3 8.6 6.4 5.2 7.5 1.0 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger Prp31_C PF09785.4 ETS87705.1 - 2e-42 144.5 0.5 4.2e-42 143.4 0.4 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 ETS87705.1 - 2.3e-41 140.5 0.6 5e-41 139.4 0.1 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 ETS87705.1 - 1.6e-20 72.6 0.0 1.8e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain HobA PF12163.3 ETS87705.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator HAT PF02184.11 ETS87706.1 - 3.5e-23 81.0 71.1 3.7e-14 52.1 1.4 14.1 15 0 0 15 15 14 7 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 ETS87706.1 - 7e-23 80.7 12.2 0.012 16.2 0.0 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 ETS87706.1 - 5.8e-22 77.7 3.7 0.00097 19.4 0.0 7.2 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS87706.1 - 6.7e-22 75.9 29.7 0.0031 18.0 0.0 11.8 7 4 7 14 14 13 6 Tetratricopeptide repeat Suf PF05843.9 ETS87706.1 - 8.4e-13 48.6 17.2 0.023 14.4 0.6 6.7 4 1 3 7 7 7 4 Suppressor of forked protein (Suf) TPR_2 PF07719.12 ETS87706.1 - 1.7e-10 39.9 17.8 0.49 10.4 0.1 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 ETS87706.1 - 1.3e-08 34.3 7.6 0.41 10.3 0.1 6.9 5 2 2 7 7 7 3 TPR repeat TPR_17 PF13431.1 ETS87706.1 - 1.4e-08 34.2 5.8 0.04 14.1 0.0 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 ETS87706.1 - 9.5e-08 31.8 25.3 0.1 12.5 0.0 8.1 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 ETS87706.1 - 3.8e-07 29.4 4.6 3 7.8 0.2 7.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 ETS87706.1 - 6.8e-07 28.6 15.5 2.5 8.1 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS87706.1 - 0.00031 20.9 26.0 4.1 8.0 0.1 8.9 10 0 0 10 10 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 ETS87706.1 - 0.032 14.1 7.4 5 7.0 0.1 5.9 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.6 ETS87706.1 - 0.11 12.3 23.0 0.05 13.3 2.7 5.8 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.23 ETS87706.1 - 0.71 9.5 10.1 26 4.6 0.2 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 ETS87706.1 - 2.2 8.4 7.9 6.4 6.9 0.0 4.3 4 0 0 4 4 4 0 c-SKI Smad4 binding domain WD40 PF00400.27 ETS87708.1 - 2.3e-30 103.3 8.5 1.9e-08 33.8 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 ETS87708.1 - 0.00015 20.0 1.7 0.029 12.4 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 ETS87708.1 - 0.00024 20.8 1.7 0.32 10.6 0.3 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.1 ETS87708.1 - 0.013 14.4 0.0 0.033 13.1 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 DUF1513 PF07433.6 ETS87708.1 - 0.025 13.4 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) RIC1 PF07064.8 ETS87709.1 - 2.5e-89 299.1 0.3 3.8e-89 298.5 0.2 1.3 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 ETS87709.1 - 7.1e-05 22.5 6.8 1.2 9.0 0.2 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat CK_II_beta PF01214.13 ETS87710.1 - 2.9e-72 242.0 0.2 3.7e-72 241.6 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4611 PF15387.1 ETS87710.1 - 0.091 12.9 2.1 0.16 12.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GST_N_3 PF13417.1 ETS87711.1 - 6.9e-21 74.2 1.5 2e-19 69.5 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS87711.1 - 1.8e-14 53.5 0.7 6.4e-13 48.5 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS87711.1 - 0.00014 21.6 0.2 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 ETS87711.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin TspO_MBR PF03073.10 ETS87712.1 - 4.7e-44 149.4 5.7 5.8e-44 149.1 3.9 1.1 1 0 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.22 ETS87713.1 - 1.3e-62 207.4 0.4 6.6e-22 77.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4110 PF13422.1 ETS87714.1 - 4.5e-29 100.1 0.6 4.5e-29 100.1 0.4 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 ETS87714.1 - 1.1e-26 92.2 14.9 2e-08 34.1 0.0 6.7 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 ETS87714.1 - 7.6e-20 70.4 11.9 1.7e-05 24.4 0.0 6.7 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 ETS87714.1 - 1.3e-19 69.6 2.3 8e-08 32.0 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 ETS87714.1 - 1.5e-14 53.4 3.0 0.00014 21.8 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 ETS87714.1 - 1.1e-11 44.0 0.9 2.3e-06 27.0 0.1 5.3 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 ETS87714.1 - 6.2e-09 35.2 5.7 0.0011 18.6 0.1 5.1 5 1 0 5 5 5 2 Kelch motif WLM PF08325.5 ETS87715.1 - 3.4e-50 170.4 0.3 3.4e-50 170.4 0.2 2.1 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 ETS87715.1 - 1.5e-07 31.4 1.6 1.5e-07 31.4 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 Rubredoxin PF00301.15 ETS87715.1 - 0.25 11.2 3.9 0.84 9.5 1.0 2.8 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.2 ETS87715.1 - 0.39 10.5 7.0 1.3 8.8 4.8 2.0 1 0 0 1 1 1 0 Double zinc ribbon Acetyltransf_3 PF13302.1 ETS87717.1 - 1e-29 103.4 0.0 1.7e-29 102.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ETS87717.1 - 0.053 13.4 0.0 0.49 10.3 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ETS87717.1 - 0.055 13.3 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS87717.1 - 0.069 12.9 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein GTP_EFTU PF00009.22 ETS87718.1 - 8e-38 129.7 0.1 1.3e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 ETS87718.1 - 1.4e-36 124.3 0.2 3e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 ETS87718.1 - 2.6e-10 40.2 0.3 5.6e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 ETS87718.1 - 0.0087 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3329 PF11808.3 ETS87719.1 - 0.007 16.4 0.9 0.29 11.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3329) OATP PF03137.15 ETS87719.1 - 0.035 12.1 2.3 0.042 11.8 0.3 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ninjurin PF04923.7 ETS87719.1 - 0.043 13.5 0.3 0.043 13.5 0.2 2.1 2 1 0 2 2 2 0 Ninjurin DUF2721 PF11026.3 ETS87719.1 - 0.051 13.2 1.5 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Tetraspannin PF00335.15 ETS87719.1 - 0.11 11.7 8.1 0.21 10.8 5.6 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.10 ETS87719.1 - 0.41 10.8 6.9 0.36 11.0 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) MARVEL PF01284.18 ETS87719.1 - 0.77 9.5 12.2 0.98 9.2 7.9 1.6 1 1 0 1 1 1 0 Membrane-associating domain ADK PF00406.17 ETS87721.1 - 6.7e-44 149.3 0.1 1.2e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 ETS87721.1 - 1e-06 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS87721.1 - 1.1e-06 29.4 0.0 1.8e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 ETS87721.1 - 3.7e-05 23.1 0.2 0.087 12.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 ETS87721.1 - 0.00031 20.6 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain PCI PF01399.22 ETS87722.1 - 3.2e-12 46.6 0.4 3.2e-11 43.4 0.0 2.7 3 1 0 3 3 3 1 PCI domain BCAS2 PF05700.6 ETS87722.1 - 0.027 13.9 1.2 0.059 12.8 0.8 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Baculo_ME53 PF06061.6 ETS87723.1 - 0.035 13.0 0.2 0.056 12.4 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 zf-C2H2 PF00096.21 ETS87723.1 - 2.3 8.7 5.6 13 6.4 1.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type HLH PF00010.21 ETS87724.1 - 0.017 14.8 0.2 0.053 13.2 0.2 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DEAD PF00270.24 ETS87726.1 - 2.1e-41 141.2 0.0 4.5e-40 136.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87726.1 - 1.5e-25 88.8 0.1 3.6e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 ETS87726.1 - 0.0015 18.7 4.7 0.0015 18.7 3.2 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 ETS87726.1 - 0.0053 16.3 1.4 0.16 11.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3334) ResIII PF04851.10 ETS87726.1 - 0.0074 16.1 0.2 0.091 12.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDK5_activator PF03261.10 ETS87726.1 - 2.9 7.1 6.1 5.4 6.2 4.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein ATP_bind_4 PF01902.12 ETS87727.1 - 0.069 12.5 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 ATP-binding region zf-CSL PF05207.8 ETS87728.1 - 4.9e-14 51.5 1.1 9.2e-14 50.6 0.8 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 ETS87728.1 - 5e-13 48.5 0.3 9.6e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3403 PF11883.3 ETS87728.1 - 0.07 13.4 0.2 1.3 9.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) DUF2039 PF10217.4 ETS87728.1 - 4.6 7.3 6.7 8.2 6.5 0.5 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) 14-3-3 PF00244.15 ETS87729.1 - 5.5e-116 385.6 3.6 6.4e-116 385.4 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 ETS87729.1 - 0.1 12.3 2.4 0.14 11.9 0.0 2.4 3 1 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain IATP PF04568.7 ETS87730.1 - 4.6e-21 74.7 1.4 4.9e-21 74.6 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF1003 PF06210.6 ETS87730.1 - 0.29 11.0 1.1 0.44 10.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.8 ETS87731.1 - 5.2e-37 126.0 0.8 1.1e-36 124.9 0.6 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 ETS87731.1 - 8.9e-22 77.4 196.3 1.4e-07 31.7 29.9 6.8 2 1 5 7 7 7 5 Nucleoporin FG repeat region Myosin_tail_1 PF01576.14 ETS87731.1 - 0.023 12.4 8.6 0.34 8.5 5.9 1.9 1 1 0 1 1 1 0 Myosin tail PV-1 PF06637.6 ETS87731.1 - 0.13 10.8 1.5 0.27 9.7 1.0 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Cortex-I_coil PF09304.5 ETS87731.1 - 0.21 11.6 4.6 0.083 12.9 0.9 1.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil Laminin_II PF06009.7 ETS87731.1 - 0.32 10.7 5.2 2.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF972 PF06156.8 ETS87731.1 - 0.33 11.3 0.8 0.81 10.0 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 ETS87731.1 - 1.3 7.9 5.5 2.1 7.3 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 ETS87731.1 - 1.7 8.2 4.3 6.2 6.3 3.0 1.9 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 ETS87731.1 - 5.9 5.2 7.0 2.5 6.4 0.4 2.0 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 ETS87731.1 - 7.6 5.0 8.2 0.22 10.1 0.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Peptidase_M1 PF01433.15 ETS87733.1 - 1.4e-138 462.2 0.0 1.9e-138 461.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 ETS87733.1 - 3.5e-88 295.9 0.4 6.9e-88 294.9 0.2 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 ETS87733.1 - 1.2e-19 70.5 0.3 2.2e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 ETS87733.1 - 0.13 11.9 0.2 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Sugar_tr PF00083.19 ETS87735.1 - 4.1e-22 78.3 28.5 2.3e-21 75.9 19.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3611 PF12263.3 ETS87735.1 - 0.0099 15.2 0.3 0.022 14.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) AP_endonuc_2 PF01261.19 ETS87736.1 - 2.5e-26 92.2 2.1 5.1e-26 91.2 1.4 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 ETS87737.1 - 1.9e-42 144.0 0.1 3.1e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 ETS87737.1 - 9.4e-12 44.6 0.0 3.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.6 ETS87737.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 ETS87737.1 - 0.0018 17.4 0.0 0.0048 16.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Podoplanin PF05808.6 ETS87737.1 - 0.2 11.1 1.0 0.44 10.0 0.7 1.5 1 0 0 1 1 1 0 Podoplanin Enolase_C PF00113.17 ETS87738.1 - 8.3e-155 514.1 0.1 1.1e-154 513.7 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 ETS87738.1 - 1.2e-58 196.7 0.4 2.2e-58 195.8 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 ETS87738.1 - 0.071 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like MAAL_C PF07476.6 ETS87738.1 - 0.082 11.8 0.1 0.81 8.5 0.1 2.2 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DRMBL PF07522.9 ETS87739.1 - 4.7e-33 113.5 0.0 9.2e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 ETS87739.1 - 1.9e-11 43.9 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CBFB_NFYA PF02045.10 ETS87740.1 - 6.8e-30 103.3 4.3 1.4e-29 102.3 3.0 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.8 ETS87740.1 - 0.26 11.1 13.5 0.37 10.6 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GFO_IDH_MocA PF01408.17 ETS87741.1 - 1.1e-17 64.7 0.4 2.4e-17 63.5 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 ETS87741.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 ETS87741.1 - 0.096 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.13 ETS87742.1 - 3.3e-06 26.9 13.5 6.7e-06 25.9 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.17 ETS87743.1 - 1.8e-21 76.8 0.0 3.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 ETS87743.1 - 9.8e-06 25.9 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 ETS87743.1 - 0.0053 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 ETS87743.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 ETS87744.1 - 2.9e-81 273.3 26.5 3.4e-81 273.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS87744.1 - 8.4e-31 106.9 48.1 8.1e-24 83.9 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2754 PF10953.3 ETS87744.1 - 0.029 14.4 0.5 0.16 12.0 0.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) MFS_1_like PF12832.2 ETS87744.1 - 0.076 12.8 0.0 0.076 12.8 0.0 3.7 5 0 0 5 5 5 0 MFS_1 like family DUF4655 PF15548.1 ETS87745.1 - 0.067 12.0 5.9 0.074 11.9 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) CBM_4_9 PF02018.12 ETS87745.1 - 0.074 13.0 2.0 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain Ub-Mut7C PF14451.1 ETS87745.1 - 0.12 11.9 1.4 0.16 11.4 0.7 1.5 2 0 0 2 2 2 0 Mut7-C ubiquitin Zn_clus PF00172.13 ETS87747.1 - 1.5e-07 31.1 10.5 2.7e-07 30.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_c3_2 PF14537.1 ETS87747.1 - 0.61 10.4 8.4 1.3 9.3 5.8 1.5 1 0 0 1 1 1 0 Cytochrome c3 FAD_binding_3 PF01494.14 ETS87748.1 - 4e-22 78.7 0.0 3.7e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS87748.1 - 1.1e-11 44.3 0.2 6.1e-07 28.6 0.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS87748.1 - 1.8e-07 31.4 0.6 5.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS87748.1 - 2.6e-07 30.5 0.3 8.1e-07 28.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 ETS87748.1 - 4.5e-06 25.4 0.2 0.0048 15.4 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 ETS87748.1 - 1.2e-05 25.2 0.1 0.00016 21.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 ETS87748.1 - 2.4e-05 23.6 0.3 0.023 13.7 0.5 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 ETS87748.1 - 7.1e-05 21.8 1.4 0.00014 20.8 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 ETS87748.1 - 0.00049 19.1 0.1 0.21 10.4 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 ETS87748.1 - 0.0008 19.5 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 ETS87748.1 - 0.0034 16.8 0.2 0.006 16.0 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 ETS87748.1 - 0.006 15.7 0.2 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 ETS87748.1 - 0.0062 15.4 0.4 0.009 14.9 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 ETS87748.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 ETS87748.1 - 0.013 14.1 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_10 PF13460.1 ETS87748.1 - 0.025 14.6 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding FAD_oxidored PF12831.2 ETS87748.1 - 0.034 13.2 0.0 0.083 11.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS87748.1 - 0.037 13.8 0.1 0.085 12.6 0.0 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 ETS87748.1 - 0.11 11.8 0.1 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 ETS87748.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 ETS87748.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 ETS87749.1 - 1.8e-65 221.2 0.0 2.2e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 ETS87750.1 - 1.9e-17 62.9 1.0 3.8e-17 62.0 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UbiA PF01040.13 ETS87751.1 - 6.2e-28 97.7 16.6 8.2e-28 97.3 11.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Shadoo PF14999.1 ETS87751.1 - 0.015 15.1 0.1 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Cupin_6 PF12852.2 ETS87752.1 - 0.059 12.9 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 ETS87753.1 - 6.5e-12 45.6 0.4 2.3e-11 43.8 0.2 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87753.1 - 8.5e-09 35.5 0.2 1.1e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87753.1 - 8.1e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS87753.1 - 0.0015 18.0 0.5 0.017 14.5 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lyase_aromatic PF00221.14 ETS87754.1 - 2.3e-159 530.8 4.4 2.9e-159 530.5 3.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Peroxidase_2 PF01328.12 ETS87756.1 - 2.3e-42 144.8 1.2 2.7e-42 144.5 0.8 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 F-box PF00646.28 ETS87757.1 - 0.00046 19.7 0.1 0.00099 18.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS87757.1 - 0.00095 18.8 0.2 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like Clr5 PF14420.1 ETS87758.1 - 1.3e-16 60.1 1.1 3e-16 59.0 0.8 1.6 1 0 0 1 1 1 1 Clr5 domain UPF0158 PF03682.8 ETS87758.1 - 0.13 11.8 0.6 0.3 10.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Acyl_transf_1 PF00698.16 ETS87760.1 - 5.3e-60 203.4 0.7 1.1e-59 202.3 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 ETS87760.1 - 1.1e-56 192.1 0.0 1.8e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 ETS87760.1 - 1.2e-51 174.9 0.1 3.3e-51 173.5 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS87760.1 - 1.2e-37 129.3 1.4 2.4e-37 128.4 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 ETS87760.1 - 2.1e-36 124.3 0.0 5e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 ETS87760.1 - 1.5e-16 60.6 0.0 3.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 ETS87760.1 - 1.2e-15 57.2 0.1 1e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 ETS87760.1 - 2.7e-10 40.2 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87760.1 - 1.1e-09 37.9 0.0 3.7e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87760.1 - 8.3e-08 32.8 0.0 2.3e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 ETS87760.1 - 2.2e-07 30.5 0.1 7.6e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 ETS87760.1 - 8.4e-07 29.4 0.0 2.9e-06 27.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 ETS87760.1 - 1.1e-06 28.2 0.1 3.5e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.20 ETS87760.1 - 3e-06 27.3 0.0 1.6e-05 25.0 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 ETS87761.1 - 1.6e-31 109.1 0.0 2.3e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 ETS87761.1 - 6e-22 77.6 0.0 1.5e-21 76.3 0.0 1.6 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 ETS87761.1 - 3e-10 39.9 0.0 4.1e-09 36.2 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 ETS87761.1 - 1.1e-05 25.6 0.3 4.4e-05 23.6 0.2 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 ETS87761.1 - 9.4e-05 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 ETS87761.1 - 0.0024 16.6 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 ETS87761.1 - 0.0026 16.6 0.0 0.16 10.8 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 ETS87761.1 - 0.02 14.8 0.0 5.8 6.8 0.0 2.7 3 0 0 3 3 3 0 NADH(P)-binding RmlD_sub_bind PF04321.12 ETS87761.1 - 0.081 11.8 0.0 1.4 7.7 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain SPC25 PF06703.6 ETS87762.1 - 3.4 7.2 7.8 0.88 9.1 0.7 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ank_2 PF12796.2 ETS87763.1 - 8.1e-65 215.1 12.5 2.2e-17 63.1 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87763.1 - 1.3e-43 144.7 13.0 5e-07 29.2 0.0 10.7 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 ETS87763.1 - 8e-38 124.6 0.3 0.00025 20.9 0.0 10.3 10 0 0 10 10 10 8 Ankyrin repeat HET PF06985.6 ETS87763.1 - 2.8e-31 108.5 0.8 4.9e-31 107.7 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 ETS87763.1 - 7.1e-29 99.1 8.6 2.1e-08 34.1 0.0 8.6 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS87763.1 - 1.8e-28 98.3 1.4 3.7e-07 30.4 0.0 7.8 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Nitro_FeMo-Co PF02579.12 ETS87763.1 - 0.002 18.1 0.2 0.051 13.6 0.0 2.9 3 0 0 3 3 3 1 Dinitrogenase iron-molybdenum cofactor Isochorismatase PF00857.15 ETS87764.1 - 2.1e-07 31.0 0.3 3e-05 24.0 0.1 2.1 1 1 1 2 2 2 2 Isochorismatase family HET PF06985.6 ETS87765.1 - 3.1e-23 82.4 1.4 4.4e-23 81.9 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 ETS87766.1 - 1.9e-22 79.7 0.0 2.5e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS87766.1 - 3.1e-09 37.0 0.0 1.3e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS87766.1 - 0.0003 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 ETS87766.1 - 0.003 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 ETS87766.1 - 0.024 13.6 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyoxalase PF00903.20 ETS87767.1 - 2.7e-12 46.7 0.0 4.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 ETS87767.1 - 1.5e-06 28.8 0.0 2.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1330 PF07045.6 ETS87767.1 - 0.12 12.2 0.1 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) SnoaL_3 PF13474.1 ETS87768.1 - 5.3e-08 32.9 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 ETS87768.1 - 5.6e-06 26.5 0.1 4e-05 23.7 0.0 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 ETS87768.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association p450 PF00067.17 ETS87770.1 - 1.6e-62 211.5 0.0 1.9e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 ETS87771.1 - 1.9e-70 237.6 0.0 2.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 ETS87771.1 - 5.3e-05 23.5 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS87771.1 - 0.00011 20.8 0.0 0.0026 16.3 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS87771.1 - 0.0004 19.4 0.4 0.0055 15.6 0.3 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 ETS87771.1 - 0.0015 17.5 0.0 0.013 14.3 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS87771.1 - 0.0049 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS87771.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 ETS87771.1 - 0.022 13.8 0.2 0.072 12.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 ETS87771.1 - 0.023 14.4 0.4 13 5.5 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 ETS87771.1 - 0.064 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS87771.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 ETS87771.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 ETS87772.1 - 8.9e-17 61.5 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87772.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS87772.1 - 0.0006 19.5 0.1 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 KR domain PA PF02225.17 ETS87772.1 - 0.014 15.0 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 PA domain Epimerase PF01370.16 ETS87772.1 - 0.044 13.2 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS87772.1 - 0.06 13.3 0.1 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 ETS87773.1 - 0.0018 16.8 0.0 0.002 16.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 ETS87774.1 - 6.7e-42 143.5 0.0 8.5e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 ETS87775.1 - 6.7e-16 58.2 0.1 1.4e-15 57.2 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS87775.1 - 1.1e-09 37.7 0.3 9e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 ETS87775.1 - 3.3e-05 24.1 0.1 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 ETS87775.1 - 0.00021 21.2 0.1 0.0008 19.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 ETS87775.1 - 0.00096 19.1 0.1 0.003 17.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 ETS87775.1 - 0.0011 17.8 0.4 0.012 14.4 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 ETS87775.1 - 0.0012 18.9 0.1 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS87775.1 - 0.0024 16.3 0.2 1.2 7.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 ETS87775.1 - 0.003 16.4 0.1 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 ETS87775.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 ETS87775.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 ETS87776.1 - 5.4e-22 77.9 0.5 1.1e-21 76.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 ETS87777.1 - 6.2e-62 208.8 0.0 7.5e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4201 PF13870.1 ETS87779.1 - 0.00047 19.6 10.0 0.00054 19.4 6.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF2968 PF11180.3 ETS87779.1 - 0.01 15.2 13.6 0.012 15.0 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 ETS87779.1 - 0.015 14.4 11.7 0.016 14.2 8.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 LETM1 PF07766.8 ETS87779.1 - 0.021 13.8 4.0 0.025 13.6 2.7 1.1 1 0 0 1 1 1 0 LETM1-like protein NPV_P10 PF05531.7 ETS87779.1 - 0.025 14.8 1.0 0.042 14.1 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 ETS87779.1 - 0.036 12.2 9.3 0.042 12.0 6.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3186 PF11382.3 ETS87779.1 - 0.065 12.3 0.7 0.067 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Paramyxo_P PF01806.12 ETS87779.1 - 0.066 12.4 3.8 0.076 12.2 2.6 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Sec8_exocyst PF04048.9 ETS87779.1 - 0.099 12.2 3.8 0.16 11.6 2.6 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain ADIP PF11559.3 ETS87779.1 - 0.12 12.2 13.6 0.14 12.0 9.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 ETS87779.1 - 0.13 10.9 8.4 0.14 10.8 5.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.7 ETS87779.1 - 0.13 12.0 3.9 0.18 11.5 2.5 1.4 1 1 0 1 1 1 0 Laminin Domain II FliD_N PF02465.13 ETS87779.1 - 0.14 12.5 2.1 0.17 12.2 1.4 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Fmp27_WPPW PF10359.4 ETS87779.1 - 0.16 10.3 7.6 0.18 10.2 5.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2857 PF11198.3 ETS87779.1 - 0.16 11.4 6.2 0.19 11.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Latarcin PF10279.4 ETS87779.1 - 0.16 12.1 6.6 0.24 11.6 4.6 1.2 1 0 0 1 1 1 0 Latarcin precursor DUF87 PF01935.12 ETS87779.1 - 0.27 11.0 1.7 0.31 10.8 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 Jnk-SapK_ap_N PF09744.4 ETS87779.1 - 0.27 11.2 8.8 0.31 11.0 6.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.3 ETS87779.1 - 0.32 10.7 13.3 0.13 12.0 6.4 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MitMem_reg PF13012.1 ETS87779.1 - 0.34 11.0 5.4 0.39 10.7 3.7 1.3 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF607 PF04678.8 ETS87779.1 - 0.66 9.8 5.3 0.8 9.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 V_ATPase_I PF01496.14 ETS87779.1 - 0.68 7.7 6.8 0.65 7.7 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 ETS87779.1 - 0.71 9.4 12.6 0.86 9.1 8.7 1.1 1 0 0 1 1 1 0 IncA protein DUF416 PF04222.7 ETS87779.1 - 0.82 8.7 7.1 0.95 8.5 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) TMPIT PF07851.8 ETS87779.1 - 1 8.3 6.9 1.2 8.1 4.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4446 PF14584.1 ETS87779.1 - 1.3 8.8 5.2 1.7 8.4 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Sec20 PF03908.8 ETS87779.1 - 1.5 8.5 4.0 2.8 7.7 2.8 1.5 1 1 0 1 1 1 0 Sec20 Atg14 PF10186.4 ETS87779.1 - 1.5 7.6 10.5 1.8 7.4 7.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 ETS87779.1 - 2 8.8 9.4 4.3 7.8 6.5 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 ETS87779.1 - 2 8.1 5.1 2.8 7.7 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3847 PF12958.2 ETS87779.1 - 2.1 8.1 13.3 0.63 9.8 7.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF948 PF06103.6 ETS87779.1 - 2.4 8.0 4.4 3.7 7.4 3.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 ETS87779.1 - 2.7 7.3 10.8 4.1 6.8 7.5 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 Mnd1 PF03962.10 ETS87779.1 - 3.8 7.1 13.0 5.5 6.6 9.0 1.4 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 ETS87779.1 - 3.8 7.3 8.4 4.4 7.1 2.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF342 PF03961.8 ETS87779.1 - 4.7 5.5 7.7 5.3 5.3 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 ETS87779.1 - 5.7 6.6 11.4 9.7 5.9 7.9 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3632 PF12311.3 ETS87780.1 - 8.6e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Aminotran_4 PF01063.14 ETS87781.1 - 3e-33 115.2 0.0 3.6e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans PF04082.13 ETS87782.1 - 7.3e-24 84.0 0.1 1e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS87783.1 - 4.5e-30 104.5 33.3 4.5e-30 104.5 23.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily 60KD_IMP PF02096.15 ETS87783.1 - 0.32 10.6 4.3 0.076 12.6 0.4 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein Dioxygenase_C PF00775.16 ETS87784.1 - 8.2e-13 48.0 2.7 2.2e-12 46.6 1.9 1.7 1 1 0 1 1 1 1 Dioxygenase MG1 PF11974.3 ETS87784.1 - 0.024 15.1 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain 2OG-FeII_Oxy PF03171.15 ETS87785.1 - 0.0075 16.5 0.0 0.062 13.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 ETS87785.1 - 0.035 14.6 0.1 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Dioxygenase_C PF00775.16 ETS87786.1 - 1.9e-10 40.3 1.1 5.1e-10 38.8 0.7 1.8 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.16 ETS87787.1 - 1.3e-14 53.8 1.3 3.2e-14 52.5 0.8 1.7 1 1 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 ETS87788.1 - 3.7e-35 122.0 5.3 5.6e-35 121.5 3.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NmrA PF05368.8 ETS87789.1 - 1.2e-26 93.3 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS87789.1 - 6e-07 29.6 0.0 8.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 ETS87789.1 - 0.0011 19.2 0.1 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 ETS87789.1 - 0.0029 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 ETS87789.1 - 0.09 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Tannase PF07519.6 ETS87790.1 - 5.3e-71 239.7 0.0 8.2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 ETS87790.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 ETS87790.1 - 0.027 14.3 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PA14_2 PF10528.4 ETS87791.1 - 9e-20 70.7 4.2 9e-20 70.7 2.9 3.3 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.7 ETS87791.1 - 3.2e-05 23.6 2.5 0.00014 21.5 0.5 2.7 2 0 0 2 2 2 1 PA14 domain NACHT PF05729.7 ETS87793.1 - 4.6e-11 42.6 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 ETS87793.1 - 1.7e-06 28.1 0.0 1.1e-05 25.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 ETS87793.1 - 0.00028 20.9 0.6 0.0017 18.3 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 ETS87793.1 - 0.0021 17.5 0.0 0.01 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 ETS87793.1 - 0.0028 17.0 0.1 0.0078 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS87793.1 - 0.0028 18.4 0.0 0.025 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 ETS87793.1 - 0.013 15.7 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 ETS87793.1 - 0.025 14.7 0.2 0.074 13.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Cas_Csy4 PF09618.5 ETS87793.1 - 0.029 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) AAA_18 PF13238.1 ETS87793.1 - 0.03 14.6 0.0 0.095 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 ETS87793.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 ETS87793.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 ETS87793.1 - 0.044 13.3 0.7 5.3 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 ETS87793.1 - 0.11 12.0 0.2 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 ETS87793.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Pec_lyase_C PF00544.14 ETS87795.1 - 1.6e-11 44.0 2.2 4e-11 42.7 1.5 1.6 1 1 0 1 1 1 1 Pectate lyase DUF3176 PF11374.3 ETS87796.1 - 1.7e-30 105.1 1.6 4.2e-30 103.8 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.6 ETS87797.1 - 1.3e-27 96.6 0.4 2.6e-27 95.6 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUR7 PF06687.7 ETS87798.1 - 4.2e-21 75.4 8.7 6.7e-21 74.8 6.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 ETS87798.1 - 0.00049 19.0 2.7 0.00049 19.0 1.9 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) Tyrosinase PF00264.15 ETS87799.1 - 4.5e-43 147.9 2.2 6.5e-43 147.4 1.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF872 PF05915.7 ETS87800.1 - 0.2 11.5 5.9 0.69 9.7 1.4 2.4 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Pmp3 PF01679.12 ETS87800.1 - 4.3 7.1 7.8 0.77 9.5 1.0 2.8 2 1 1 3 3 3 0 Proteolipid membrane potential modulator C2 PF00168.25 ETS87801.1 - 2.5e-69 229.1 0.5 4.1e-21 74.6 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 ETS87801.1 - 0.031 14.3 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) SprT-like PF10263.4 ETS87802.1 - 0.0079 15.8 1.9 0.018 14.6 1.2 1.7 1 1 0 1 1 1 1 SprT-like family Nodulin_late PF07127.6 ETS87802.1 - 0.17 12.0 1.5 0.39 10.8 1.0 1.5 1 0 0 1 1 1 0 Late nodulin protein WLM PF08325.5 ETS87802.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.7 3 0 0 3 3 3 0 WLM domain FAD_binding_3 PF01494.14 ETS87803.1 - 5.5e-19 68.4 0.0 1.4e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS87803.1 - 3.2e-11 42.7 1.2 8.2e-10 38.1 0.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS87803.1 - 1e-08 35.0 0.3 2.3e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 ETS87803.1 - 1e-06 28.8 0.9 2e-06 27.8 0.4 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 ETS87803.1 - 2.2e-06 27.9 0.3 6.4e-06 26.4 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 ETS87803.1 - 9.9e-06 24.6 3.2 2.9e-05 23.0 1.4 2.0 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 ETS87803.1 - 4.2e-05 22.8 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 ETS87803.1 - 0.0002 20.5 0.1 0.033 13.2 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 ETS87803.1 - 0.00022 19.8 0.5 0.00034 19.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 ETS87803.1 - 0.00027 19.9 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 ETS87803.1 - 0.00097 18.1 0.9 0.0014 17.5 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 ETS87803.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 ETS87803.1 - 0.0067 15.5 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 ETS87803.1 - 0.025 14.2 0.3 0.045 13.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 ETS87803.1 - 0.035 13.4 0.1 0.11 11.8 0.1 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 ETS87803.1 - 0.038 13.7 0.2 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 ETS87803.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 ETS87803.1 - 0.13 12.2 0.2 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 ETS87804.1 - 1.1e-11 44.1 0.1 2.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87804.1 - 1.1e-05 25.1 12.6 2.1e-05 24.2 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.20 ETS87805.1 - 6.4e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 ETS87805.1 - 2.1e-08 34.2 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 ETS87805.1 - 8.2e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 ETS87805.1 - 8.4e-07 29.4 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 ETS87805.1 - 1e-05 25.2 0.2 7.8e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 ETS87805.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3602 PF12223.3 ETS87806.1 - 2.2e-15 56.8 22.4 3.1e-11 43.4 4.4 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glyco_hydro_10 PF00331.15 ETS87807.1 - 3.8e-105 351.4 0.2 4.3e-105 351.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 ETS87807.1 - 0.023 15.1 0.0 0.33 11.4 0.0 2.4 1 1 1 2 2 2 0 Sugar-binding cellulase-like DUF4339 PF14237.1 ETS87807.1 - 0.046 13.3 0.1 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) ATG22 PF11700.3 ETS87808.1 - 3.9e-202 671.9 12.7 4.5e-202 671.7 8.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 ETS87808.1 - 0.00098 17.9 47.9 0.058 12.1 6.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily BAH PF01426.13 ETS87809.1 - 6.8e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 ETS87809.1 - 0.00014 21.4 2.6 0.00036 20.1 1.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 ETS87809.1 - 0.019 15.1 0.1 0.099 12.7 0.0 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 ETS87809.1 - 0.024 14.6 0.3 0.053 13.5 0.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 ETS87809.1 - 0.06 13.3 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.3 ETS87809.1 - 0.13 12.1 1.7 0.28 11.1 1.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain p450 PF00067.17 ETS87810.1 - 1.2e-46 159.2 0.0 1.5e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEAT_PBS PF03130.11 ETS87810.1 - 0.13 12.8 0.2 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Bac_luciferase PF00296.15 ETS87811.1 - 7.8e-60 202.5 1.5 1e-59 202.1 1.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Oxidored_FMN PF00724.15 ETS87812.1 - 2.1e-73 247.3 0.0 2.9e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 ETS87812.1 - 0.00086 18.2 0.0 0.056 12.2 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF1848 PF08902.6 ETS87812.1 - 0.058 12.9 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) TMP-TENI PF02581.12 ETS87812.1 - 0.061 12.4 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Fungal_trans PF04082.13 ETS87813.1 - 1.1e-23 83.4 0.0 2.3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87813.1 - 1.7e-08 34.2 9.2 2.8e-08 33.5 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.7 ETS87815.1 - 9.5e-23 80.5 0.0 3.8e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87815.1 - 2.3e-17 63.0 0.0 3.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS87815.1 - 4.7e-17 62.1 0.0 7.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87815.1 - 2.7e-13 50.2 0.0 5.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87815.1 - 8.4e-12 45.6 0.0 3.4e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87815.1 - 1.3e-11 44.7 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS87815.1 - 7.8e-11 41.5 0.0 1.7e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 ETS87815.1 - 5.1e-09 35.6 0.0 7.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 ETS87815.1 - 7.5e-08 32.4 0.0 2.3e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 ETS87815.1 - 1.5e-06 27.7 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 ETS87815.1 - 7.2e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 ETS87815.1 - 0.00099 18.1 0.0 0.028 13.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 ETS87815.1 - 0.0014 17.8 0.0 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase RrnaAD PF00398.15 ETS87815.1 - 0.0043 16.1 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 ETS87815.1 - 0.0047 16.0 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 ETS87815.1 - 0.0063 15.4 0.0 0.018 13.9 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 ETS87815.1 - 0.02 14.5 0.0 0.5 9.9 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.12 ETS87815.1 - 0.021 13.8 0.0 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 ETS87815.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 ETS87815.1 - 0.022 13.9 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 ETS87815.1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.18 ETS87816.1 - 3.7e-06 26.8 0.4 7.4e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3716 PF12511.3 ETS87817.1 - 1.6e-18 66.0 1.2 2.8e-18 65.2 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.7 ETS87817.1 - 0.00076 18.8 0.2 0.019 14.3 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 ETS87817.1 - 0.0033 16.8 0.0 0.0083 15.6 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.3 ETS87817.1 - 0.0036 17.2 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like DAO PF01266.19 ETS87817.1 - 0.035 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pirin_C PF05726.8 ETS87817.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Pirin C-terminal cupin domain ADH_zinc_N PF00107.21 ETS87818.1 - 4.4e-11 42.4 0.6 1.1e-10 41.1 0.4 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS87818.1 - 2.9e-05 23.8 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 ETS87818.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase COesterase PF00135.23 ETS87819.1 - 6.7e-80 269.3 0.3 8.6e-80 268.9 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS87819.1 - 5.2e-05 22.9 0.1 0.00018 21.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold AAA_10 PF12846.2 ETS87822.1 - 6e-08 32.4 0.0 4.3e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.12 ETS87822.1 - 0.0011 18.8 0.2 0.0085 15.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 ETS87822.1 - 0.032 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 ETS87822.1 - 0.036 13.5 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 ETS87822.1 - 0.042 13.3 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_22 PF13401.1 ETS87822.1 - 0.11 12.6 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RXT2_N PF08595.6 ETS87822.1 - 0.38 10.5 3.0 0.76 9.5 2.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal MFS_1 PF07690.11 ETS87823.1 - 1.6e-31 109.3 28.7 4e-31 108.0 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.6 ETS87824.1 - 1.8e-86 290.7 1.1 5.8e-86 289.0 0.8 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 ETS87824.1 - 0.0068 16.1 0.1 4 7.1 0.0 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family PAN_4 PF14295.1 ETS87826.1 - 0.00092 18.8 2.0 0.0015 18.2 1.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 ETS87826.1 - 0.0052 16.3 1.0 0.012 15.2 0.7 1.6 1 0 0 1 1 1 1 PAN-like domain RskA PF10099.4 ETS87826.1 - 0.023 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2162 PF09930.4 ETS87826.1 - 0.027 13.6 0.4 0.037 13.1 0.3 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FtsX PF02687.16 ETS87826.1 - 0.055 13.2 1.0 0.077 12.7 0.7 1.2 1 0 0 1 1 1 0 FtsX-like permease family PAN_1 PF00024.21 ETS87826.1 - 0.062 13.0 0.3 0.062 13.0 0.2 1.8 2 0 0 2 2 2 0 PAN domain PAN_2 PF08276.6 ETS87826.1 - 0.12 12.2 1.5 0.23 11.3 1.1 1.5 1 0 0 1 1 1 0 PAN-like domain Herpes_capsid PF06112.6 ETS87826.1 - 0.22 11.5 2.7 0.36 10.8 1.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SBP_bac_10 PF07596.6 ETS87826.1 - 0.29 11.1 6.4 0.37 10.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Sporozoite_P67 PF05642.6 ETS87826.1 - 5.1 4.8 11.2 6.7 4.4 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.14 ETS87827.1 - 8.1e-78 261.9 0.0 1e-77 261.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 ETS87827.1 - 2.6e-05 23.3 0.0 0.00038 19.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS87827.1 - 4.5e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 ETS87827.1 - 6.8e-05 22.1 0.0 0.093 11.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 ETS87827.1 - 0.00028 20.0 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 ETS87827.1 - 0.0014 19.0 0.0 0.0062 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS87827.1 - 0.0025 16.3 0.0 0.0051 15.3 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 ETS87827.1 - 0.003 17.4 0.0 0.034 14.0 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS87827.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 ETS87827.1 - 0.0072 15.2 0.2 0.042 12.7 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 ETS87827.1 - 0.012 14.5 0.0 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 ETS87827.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_zinc_N PF00107.21 ETS87828.1 - 8.1e-26 90.1 0.2 1.3e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 ETS87828.1 - 3.2e-12 46.1 0.0 1.3e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS87828.1 - 1.2e-09 39.1 0.2 2.7e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 ETS87828.1 - 0.00037 20.4 0.8 0.00088 19.2 0.5 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 ETS87828.1 - 0.00044 20.3 1.0 0.00087 19.3 0.7 1.5 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 ETS87829.1 - 1e-15 57.3 0.4 1.7e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS87830.1 - 3.7e-25 88.3 18.1 3.7e-25 88.3 12.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS87830.1 - 1 9.1 9.0 0.043 13.5 0.8 2.8 3 0 0 3 3 3 0 MFS_1 like family adh_short PF00106.20 ETS87831.1 - 8.1e-20 71.3 0.0 1.1e-17 64.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87831.1 - 8.3e-12 45.3 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 ETS87831.1 - 0.0046 16.4 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS87831.1 - 0.0055 16.3 0.0 0.75 9.4 0.0 2.4 1 1 1 2 2 2 2 KR domain NAD_binding_10 PF13460.1 ETS87831.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS87831.1 - 0.12 12.1 0.0 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pro-kuma_activ PF09286.6 ETS87832.1 - 7e-29 100.7 0.3 1.4e-28 99.6 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF1593 PF07632.6 ETS87833.1 - 5.1e-82 275.0 0.8 7.1e-82 274.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) CorA PF01544.13 ETS87834.1 - 1e-05 24.7 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF608 PF04685.8 ETS87834.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 DUF1903 PF08991.5 ETS87836.1 - 1.2e-06 28.5 0.7 1.7e-06 28.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 ETS87836.1 - 3.3e-05 23.6 2.8 0.00013 21.8 1.8 1.9 1 1 1 2 2 2 1 CHCH domain Pet191_N PF10203.4 ETS87836.1 - 0.04 13.9 3.3 0.078 13.0 2.3 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 ETS87836.1 - 0.078 12.8 4.6 0.51 10.2 3.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF4110 PF13422.1 ETS87836.1 - 0.11 12.3 1.3 0.13 12.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) COX17 PF05051.8 ETS87836.1 - 0.53 10.3 3.0 1.5 8.9 1.5 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 ETS87836.1 - 0.59 9.9 6.0 0.85 9.4 0.5 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NatB_MDM20 PF09797.4 ETS87837.1 - 2.6e-37 128.4 0.3 4.3e-37 127.6 0.2 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4363 PF14276.1 ETS87837.1 - 0.084 12.5 1.3 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Ilm1 PF10311.4 ETS87838.1 - 6.4e-48 162.3 0.2 7.4e-48 162.1 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF3165 PF11364.3 ETS87838.1 - 0.063 13.4 3.4 0.45 10.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) SecD_SecF PF02355.11 ETS87838.1 - 0.18 10.9 1.0 0.34 10.0 0.1 1.8 1 1 1 2 2 2 0 Protein export membrane protein Prenyltrans PF00432.16 ETS87839.1 - 4.3e-38 128.5 0.1 2.1e-08 33.5 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 ETS87839.1 - 1e-24 87.1 0.0 6.3e-15 55.5 0.0 3.5 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 ETS87839.1 - 7e-08 32.4 0.0 0.018 15.0 0.0 3.6 3 1 0 3 3 3 2 Prenyltransferase-like Pyr_redox_3 PF13738.1 ETS87840.1 - 4.1e-19 69.4 0.0 7.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS87840.1 - 1.8e-11 42.9 0.2 1.1e-10 40.4 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS87840.1 - 3.4e-10 39.7 0.0 1e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS87840.1 - 1.3e-05 24.3 0.1 0.00043 19.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS87840.1 - 0.00063 19.5 0.0 0.048 13.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 ETS87840.1 - 0.0097 14.8 0.0 0.65 8.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 ETS87840.1 - 0.03 13.4 1.2 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 ETS87840.1 - 0.41 9.6 1.0 0.71 8.8 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 ETS87841.1 - 1.4e-23 83.1 34.3 1.4e-23 83.1 23.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2636 PF11120.3 ETS87841.1 - 1.1 8.7 4.1 2.3 7.8 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2636) Bac_luciferase PF00296.15 ETS87842.1 - 1.7e-63 214.6 0.2 2.4e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 ETS87843.1 - 4.5e-60 203.3 0.7 5.8e-60 203.0 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TRAPPC10 PF12584.3 ETS87844.1 - 1.6e-20 73.1 0.0 2.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 ETS87844.1 - 0.00019 20.9 1.0 0.00032 20.2 0.7 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.12 ETS87845.1 - 4.2e-76 255.6 1.2 4.9e-76 255.4 0.8 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3620 PF12281.3 ETS87845.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) M20_dimer PF07687.9 ETS87846.1 - 1.7e-22 79.2 0.0 6.4e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 ETS87846.1 - 1.2e-19 70.5 0.3 1.6e-19 70.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 ETS87846.1 - 0.0046 16.7 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Dioxygenase_C PF00775.16 ETS87847.1 - 6.5e-11 41.8 3.9 5.7e-10 38.7 2.7 2.1 1 1 0 1 1 1 1 Dioxygenase MG1 PF11974.3 ETS87847.1 - 0.07 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Lactonase PF10282.4 ETS87849.1 - 1.3e-06 27.7 0.0 0.0073 15.4 0.0 2.9 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Me-amine-dh_H PF06433.6 ETS87849.1 - 0.14 10.7 0.0 0.42 9.2 0.0 1.8 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Pkinase PF00069.20 ETS87850.1 - 9.5e-67 224.8 0.0 1.4e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87850.1 - 1.6e-40 138.8 0.0 2.6e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 ETS87850.1 - 7.5e-09 34.9 0.0 1.9e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 ETS87850.1 - 0.0065 15.5 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS87850.1 - 0.025 14.3 2.0 0.07 12.8 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 ETS87850.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M28 PF04389.12 ETS87851.1 - 8.5e-40 136.3 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Pectate_lyase_3 PF12708.2 ETS87852.1 - 1.2e-14 55.0 0.2 1.4e-14 54.7 0.1 1.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein RE_NgoPII PF09521.5 ETS87852.1 - 0.024 13.4 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease End_N_terminal PF12218.3 ETS87852.1 - 0.033 13.6 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase p450 PF00067.17 ETS87853.1 - 1.4e-66 224.9 0.0 1.7e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RecO_C PF02565.10 ETS87853.1 - 0.09 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Recombination protein O C terminal Oxidored_FMN PF00724.15 ETS87855.1 - 8.8e-45 153.1 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 ETS87856.1 - 4.8e-37 127.4 52.7 4.8e-37 127.4 36.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fig1 PF12351.3 ETS87856.1 - 3.3 7.5 12.0 1 9.2 1.2 2.6 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Methyltransf_23 PF13489.1 ETS87857.1 - 3.7e-12 46.2 0.0 5.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS87857.1 - 6.9e-10 38.7 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS87857.1 - 9.1e-08 32.6 0.0 5.2e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS87857.1 - 3.1e-07 30.8 0.0 8.4e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS87857.1 - 1.3e-05 25.1 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS87857.1 - 4.8e-05 23.6 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS87857.1 - 5.8e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 ETS87857.1 - 0.00057 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 ETS87857.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 ETS87857.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 ETS87857.1 - 0.0047 16.1 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 ETS87857.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 ETS87857.1 - 0.017 14.1 0.0 0.081 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 ETS87857.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3181 PF11378.3 ETS87857.1 - 0.06 13.3 0.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3181) SE PF08491.5 ETS87857.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase IDO PF01231.13 ETS87858.1 - 4.3e-15 55.0 0.0 1.6e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aldo_ket_red PF00248.16 ETS87859.1 - 2e-46 158.0 0.0 2.4e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2608 PF11019.3 ETS87859.1 - 0.045 12.7 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) p450 PF00067.17 ETS87861.1 - 2.4e-18 65.8 0.0 1.2e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF3944 PF13099.1 ETS87861.1 - 0.0011 18.4 0.1 0.0028 17.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3944) CoxIIa PF08113.6 ETS87861.1 - 2.2 8.0 6.0 4.1 7.1 4.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Amidoligase_2 PF12224.3 ETS87862.1 - 1.7e-18 67.1 0.1 4.5e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Dscam_C PF12355.3 ETS87863.1 - 0.58 10.4 3.8 0.93 9.7 2.6 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Nitroreductase PF00881.19 ETS87865.1 - 9.7e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PQ-loop PF04193.9 ETS87866.1 - 8.2e-12 44.4 19.4 2.9e-07 29.9 0.6 3.7 3 1 0 3 3 3 2 PQ loop repeat DUF1469 PF07332.6 ETS87866.1 - 0.018 14.7 0.1 0.018 14.7 0.1 2.8 3 1 0 4 4 4 0 Protein of unknown function (DUF1469) Fungal_trans PF04082.13 ETS87867.1 - 8.2e-14 51.1 0.8 8.2e-14 51.1 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain bZIP_2 PF07716.10 ETS87867.1 - 0.059 13.1 2.7 0.16 11.8 1.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.13 ETS87867.1 - 0.14 12.0 6.4 0.32 10.9 4.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 ETS87868.1 - 3.9e-06 26.9 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 ETS87868.1 - 0.00028 20.6 0.0 0.00084 19.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 ETS87868.1 - 0.0014 19.0 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MBOAT_2 PF13813.1 ETS87869.1 - 4.6e-21 74.6 7.6 4.1e-20 71.6 2.8 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family adh_short PF00106.20 ETS87871.1 - 3.7e-13 49.7 0.0 2.8e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 ETS87871.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 ETS87871.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 ETS87871.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 ETS87871.1 - 0.021 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 ETS87871.1 - 0.098 12.4 0.6 0.71 9.7 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HET PF06985.6 ETS87873.1 - 6.7e-38 129.9 0.1 8.1e-37 126.4 0.1 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 ETS87873.1 - 2.4e-10 39.6 0.2 2.3e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 ETS87873.1 - 7.9e-10 38.9 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 ETS87873.1 - 6.3e-08 32.6 4.1 0.00017 21.7 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 ETS87873.1 - 8.8e-07 29.2 0.0 2.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 ETS87873.1 - 5.1e-06 26.2 0.1 0.00053 19.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Fungal_trans PF04082.13 ETS87875.1 - 1.1e-20 73.6 0.0 3.5e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87875.1 - 1.9e-06 27.6 8.0 3.9e-06 26.6 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3573 PF12097.3 ETS87875.1 - 0.6 8.6 1.8 0.92 8.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FAA_hydrolase PF01557.13 ETS87876.1 - 2.9e-51 174.0 0.0 3.8e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 ETS87876.1 - 8.2e-26 90.0 0.0 1.6e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 ETS87877.1 - 8e-183 607.6 0.0 9.1e-183 607.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.1 ETS87878.1 - 5.9e-58 196.3 46.6 7.9e-58 195.9 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS87878.1 - 8.1e-27 93.6 42.6 1.1e-26 93.2 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 ETS87879.1 - 8.1e-69 232.3 0.0 9.1e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 ETS87880.1 - 2.5e-21 76.0 5.0 3.9e-21 75.4 3.5 1.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 ETS87880.1 - 0.00018 21.2 17.4 0.0032 17.2 12.0 2.4 1 1 0 1 1 1 1 Right handed beta helix region NmrA PF05368.8 ETS87881.1 - 2.6e-24 85.7 1.9 3.2e-24 85.4 1.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 ETS87881.1 - 1.2e-18 67.7 1.8 1.8e-18 67.2 1.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 ETS87881.1 - 9e-08 31.8 0.4 1.9e-07 30.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 ETS87881.1 - 4.1e-06 26.0 0.4 6.6e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 ETS87881.1 - 0.00023 21.4 0.6 0.00023 21.4 0.4 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 ETS87881.1 - 0.00082 18.3 1.4 0.0023 16.8 0.1 2.2 3 0 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 ETS87881.1 - 0.00092 17.9 0.1 0.0028 16.3 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 ETS87881.1 - 0.0032 17.3 0.4 0.0032 17.3 0.3 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 ETS87881.1 - 0.0067 16.5 2.7 0.0095 16.0 0.6 2.0 2 0 0 2 2 2 1 CoA binding domain 2-Hacid_dh_C PF02826.14 ETS87881.1 - 0.031 13.4 0.1 0.07 12.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 ETS87881.1 - 0.086 11.9 1.7 0.15 11.1 0.3 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sybindin PF04099.7 ETS87881.1 - 0.1 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Sybindin-like family TrkA_N PF02254.13 ETS87881.1 - 0.16 11.9 1.9 0.39 10.7 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 ETS87881.1 - 0.31 10.6 4.2 0.12 12.0 0.5 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dabb PF07876.7 ETS87882.1 - 9.8e-14 51.5 0.1 1.1e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldedh PF00171.17 ETS87883.1 - 3.3e-160 533.4 0.0 3.8e-160 533.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS87883.1 - 0.0085 14.8 0.0 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Rhodanese PF00581.15 ETS87885.1 - 2.6e-08 34.1 0.0 3.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain H_lectin PF09458.5 ETS87887.1 - 2e-29 101.0 0.6 6e-11 41.8 0.5 3.7 3 0 0 3 3 3 3 H-type lectin domain Tannase PF07519.6 ETS87888.1 - 5.2e-99 332.0 1.5 4.3e-98 329.0 1.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase BSMAP PF12280.3 ETS87889.1 - 1 9.2 7.6 0.63 9.9 0.8 2.2 1 1 1 2 2 2 0 Brain specific membrane anchored protein Pro-kuma_activ PF09286.6 ETS87890.1 - 6.4e-30 104.0 0.1 1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 ETS87890.1 - 0.002 17.3 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family HET PF06985.6 ETS87891.1 - 3.6e-31 108.1 0.0 6.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 ETS87892.1 - 1.5e-18 67.3 0.2 2.2e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 ETS87892.1 - 6.8e-11 42.1 0.2 1.1e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 ETS87892.1 - 0.0018 17.2 0.1 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 ETS87892.1 - 0.0043 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 ETS87892.1 - 0.011 15.7 0.2 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 ETS87892.1 - 0.041 13.3 0.1 0.09 12.1 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CRS1_YhbY PF01985.16 ETS87892.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain MFS_1 PF07690.11 ETS87893.1 - 1.8e-31 109.1 42.6 2.2e-31 108.8 29.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily IGPD PF00475.13 ETS87893.1 - 0.034 14.0 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Aldo_ket_red PF00248.16 ETS87894.1 - 2.7e-37 128.1 0.0 3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 ETS87895.1 - 1.1e-63 215.3 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 ETS87896.1 - 7.6e-55 186.1 55.8 9.5e-55 185.8 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 ETS87896.1 - 7e-20 70.8 45.5 9.6e-20 70.3 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease Hum_adeno_E3A PF05393.6 ETS87896.1 - 0.21 11.3 5.3 3.4 7.3 0.1 3.6 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Aminotran_3 PF00202.16 ETS87897.1 - 2.3e-93 312.7 0.0 2.8e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.17 ETS87898.1 - 4.4e-171 569.2 0.0 5e-171 569.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.15 ETS87899.1 - 4.7e-166 552.6 0.0 5.8e-166 552.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 ETS87899.1 - 3.3e-18 65.6 0.0 8.1e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 ETS87899.1 - 1.7e-12 47.2 0.0 3.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.17 ETS87900.1 - 4.9e-46 157.2 0.0 9.7e-46 156.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 ETS87901.1 - 2.6e-23 81.9 0.0 3e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.4 ETS87901.1 - 1.7e-06 27.6 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.10 ETS87901.1 - 3.8e-05 22.7 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 AAT PF03417.11 ETS87902.1 - 3.4e-30 105.1 0.0 4.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 ETS87902.1 - 8.8e-05 22.7 0.0 0.00023 21.4 0.0 1.7 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans_2 PF11951.3 ETS87903.1 - 3.5e-45 154.2 5.8 9e-45 152.8 4.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS87903.1 - 7.5e-07 28.9 9.2 1.5e-06 28.0 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 ETS87904.1 - 1.7e-71 240.8 0.0 2.7e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS87904.1 - 9.1e-29 100.5 0.0 1.5e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 ETS87904.1 - 2.5e-08 33.2 1.2 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 ETS87904.1 - 5.6e-07 28.7 0.2 0.0015 17.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 ETS87904.1 - 0.00015 21.6 1.9 0.00025 20.9 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS87904.1 - 0.0067 15.3 0.2 0.0098 14.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS87904.1 - 0.011 15.6 0.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 ETS87904.1 - 0.014 15.5 0.4 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS87904.1 - 0.042 12.9 0.1 0.33 9.9 0.1 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 ETS87904.1 - 0.057 11.8 0.4 0.19 10.1 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Ribonuc_L-PSP PF01042.16 ETS87905.1 - 5e-11 42.4 0.0 6.6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.17 ETS87906.1 - 9.8e-136 452.7 0.1 1.1e-135 452.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 ETS87906.1 - 0.00083 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ABC2_membrane PF01061.19 ETS87907.1 - 7.5e-74 247.4 65.2 1.8e-39 135.1 12.4 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 ETS87907.1 - 1.6e-36 125.6 0.0 1.2e-16 61.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 ETS87907.1 - 2e-34 117.3 13.4 5.4e-33 112.7 0.0 4.0 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 ETS87907.1 - 1.9e-19 69.5 0.0 4.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 ETS87907.1 - 3.5e-09 36.3 0.0 3.3e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 ETS87907.1 - 0.00012 21.5 1.2 0.022 14.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 ETS87907.1 - 0.00015 21.7 1.4 0.02 14.8 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 ETS87907.1 - 0.00024 21.0 0.1 0.0046 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS87907.1 - 0.00063 19.4 0.5 1.2 8.8 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain DUF258 PF03193.11 ETS87907.1 - 0.00095 18.3 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 ETS87907.1 - 0.0043 16.5 1.9 0.028 13.8 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 ETS87907.1 - 0.0087 16.8 0.0 0.17 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 ETS87907.1 - 0.011 15.9 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 ETS87907.1 - 0.013 15.6 0.1 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 ETS87907.1 - 0.018 15.0 0.1 0.43 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 ETS87907.1 - 0.021 13.7 0.1 5.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 ETS87907.1 - 0.026 14.1 1.2 2.8 7.5 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 ETS87907.1 - 0.041 13.8 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 ETS87907.1 - 0.045 12.7 54.2 0.088 11.8 15.5 3.3 2 1 0 2 2 2 0 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 ETS87907.1 - 0.062 12.7 0.1 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 ETS87907.1 - 0.066 13.5 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 ETS87907.1 - 0.17 11.5 1.6 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 ETS87907.1 - 0.2 10.8 0.0 9.2 5.4 0.0 2.8 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 ETS87907.1 - 0.35 10.2 1.3 7.6 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain PDR_assoc PF08370.6 ETS87907.1 - 1.5 8.4 13.0 0.11 12.0 0.9 3.3 3 0 0 3 3 2 0 Plant PDR ABC transporter associated Fungal_trans PF04082.13 ETS87908.1 - 1.6e-18 66.5 0.1 3.1e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.17 ETS87910.1 - 3.4e-76 257.0 0.3 4.7e-76 256.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PNP_UDP_1 PF01048.15 ETS87911.1 - 5.1e-11 42.0 0.2 4.9e-10 38.7 0.2 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Myco_19_kDa PF05481.7 ETS87911.1 - 0.026 14.3 0.2 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Ank_2 PF12796.2 ETS87912.1 - 3e-59 197.3 4.4 2.7e-15 56.4 0.0 5.4 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 ETS87912.1 - 5.4e-25 85.9 6.4 0.00056 19.5 0.1 9.4 7 1 1 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 ETS87912.1 - 1.4e-18 65.0 2.2 0.16 12.2 0.0 9.2 7 1 1 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 ETS87912.1 - 7.3e-18 64.5 4.8 4e-05 24.0 0.0 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 ETS87912.1 - 1.4e-14 54.0 0.0 3.1e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 ETS87912.1 - 1.6e-13 50.3 1.6 0.022 14.9 0.0 8.0 2 2 7 9 9 9 5 Ankyrin repeats (many copies) DUF249 PF03158.8 ETS87912.1 - 0.00016 21.2 0.0 0.098 12.1 0.0 3.9 4 0 0 4 4 4 1 Multigene family 530 protein AAA_16 PF13191.1 ETS87912.1 - 0.00021 21.3 0.3 0.0011 18.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS87912.1 - 0.0091 16.1 0.0 0.039 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 ETS87912.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Arch_ATPase PF01637.13 ETS87912.1 - 0.044 13.4 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 ETS87912.1 - 0.088 11.7 0.2 0.25 10.2 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain PIF1 PF05970.9 ETS87912.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Proteasome PF00227.21 ETS87914.1 - 5.6e-44 149.7 0.4 3.1e-30 104.8 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 ETS87914.1 - 1.4e-11 43.4 0.9 1.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Glyco_hydro_61 PF03443.9 ETS87915.1 - 1.1e-46 159.4 0.0 1.1e-46 159.4 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 ETS87915.1 - 5.9e-08 32.2 7.7 5.9e-08 32.2 5.4 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DNA_pol_phi PF04931.8 ETS87916.1 - 3.1e-44 150.9 30.8 2.8e-43 147.7 21.3 2.3 1 1 0 1 1 1 1 DNA polymerase phi Uteroglobin PF01099.12 ETS87916.1 - 0.017 14.8 1.2 0.098 12.4 0.0 2.9 2 0 0 2 2 2 0 Uteroglobin family Vmethyltransf PF01660.12 ETS87916.1 - 0.026 13.2 0.1 0.045 12.4 0.1 1.3 1 0 0 1 1 1 0 Viral methyltransferase Rhodanese PF00581.15 ETS87917.1 - 1.9e-12 47.5 0.0 4.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain COesterase PF00135.23 ETS87918.1 - 1.1e-65 222.4 0.4 4e-65 220.5 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS87918.1 - 6.4e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold BTB PF00651.26 ETS87919.1 - 9.1e-06 25.6 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.24 ETS87920.1 - 2.6e-18 66.0 0.1 2e-17 63.1 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87920.1 - 1.1e-08 34.7 0.0 5.5e-08 32.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 ETS87920.1 - 0.001 19.1 0.0 0.0058 16.7 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 ETS87920.1 - 0.0033 17.2 0.0 0.042 13.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-HC5HC2H_2 PF13832.1 ETS87921.1 - 3.4e-21 75.3 15.3 1.6e-19 69.9 1.6 4.1 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 ETS87921.1 - 1.4e-16 60.3 4.0 1.4e-16 60.3 2.8 5.0 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.13 ETS87921.1 - 3.9e-16 58.8 0.1 7.7e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 ETS87921.1 - 1.4e-13 50.2 53.5 1.4e-07 31.1 4.1 6.1 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 ETS87921.1 - 7.3e-10 37.9 4.0 7.3e-10 37.9 2.8 5.3 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 ETS87921.1 - 2.9e-05 23.7 39.2 0.033 13.9 0.7 4.9 4 0 0 4 4 4 3 Prokaryotic RING finger family 1 C1_1 PF00130.17 ETS87921.1 - 0.00028 20.5 0.6 0.00028 20.5 0.4 4.8 5 0 0 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) dCMP_cyt_deam_1 PF00383.17 ETS87922.1 - 6.8e-24 83.4 0.0 9.6e-24 82.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 ETS87922.1 - 6e-05 22.9 2.4 0.056 13.2 1.6 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 ETS87922.1 - 0.0015 18.2 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase HCNGP PF07818.8 ETS87926.1 - 1.1e-28 99.0 0.1 1.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein AAA PF00004.24 ETS87927.1 - 5e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 ETS87927.1 - 8.5e-08 32.3 0.1 6.4e-06 26.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 ETS87927.1 - 9.6e-07 28.8 0.0 7.7e-06 25.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 ETS87927.1 - 1.8e-06 27.7 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 ETS87927.1 - 2.5e-06 27.6 0.0 0.001 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 ETS87927.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 ETS87927.1 - 0.00016 20.7 0.0 0.00058 18.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 ETS87927.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 ETS87927.1 - 0.00059 20.6 0.8 0.002 18.9 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS87927.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 ETS87927.1 - 0.0016 18.3 0.0 0.0063 16.3 0.0 2.0 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 ETS87927.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 ETS87927.1 - 0.0023 18.2 0.1 0.0081 16.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 ETS87927.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 ETS87927.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 ETS87927.1 - 0.0041 17.2 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 ETS87927.1 - 0.0051 15.9 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 ETS87927.1 - 0.0074 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 ETS87927.1 - 0.0089 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 ETS87927.1 - 0.0093 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4200 PF13863.1 ETS87927.1 - 0.01 15.8 1.3 0.01 15.8 0.9 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) AAA_24 PF13479.1 ETS87927.1 - 0.018 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 ETS87927.1 - 0.02 14.0 0.5 0.11 11.5 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 ETS87927.1 - 0.021 14.8 0.0 0.064 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 ETS87927.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 ETS87927.1 - 0.025 14.2 0.1 0.14 11.8 0.0 2.3 2 1 0 2 2 1 0 Archaeal ATPase ResIII PF04851.10 ETS87927.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 ETS87927.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 ETS87927.1 - 0.032 13.8 0.5 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 ETS87927.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 ETS87927.1 - 0.046 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 eIF-1a PF01176.14 ETS87927.1 - 0.047 13.1 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_30 PF13604.1 ETS87927.1 - 0.07 12.7 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 ETS87927.1 - 0.08 12.3 0.0 1.4 8.2 0.0 2.5 3 0 0 3 3 2 0 Thymidylate kinase Parvo_NS1 PF01057.12 ETS87927.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 ETS87927.1 - 0.32 11.2 5.1 2.7 8.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain SIS PF01380.17 ETS87928.1 - 4.7e-56 187.9 0.0 4.5e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 ETS87928.1 - 3.9e-27 94.8 0.0 2.3e-18 66.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 ETS87928.1 - 2.3e-20 72.8 0.0 5.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 ETS87928.1 - 1.2e-11 44.4 0.0 2.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 ETS87928.1 - 2.9e-06 26.1 0.0 4.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 ETS87928.1 - 0.028 14.1 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 0 SIS domain Proteasome PF00227.21 ETS87929.1 - 7.6e-32 110.1 0.0 9.2e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit KAR9 PF08580.5 ETS87931.1 - 1e-139 466.9 0.0 1.8e-139 466.1 0.0 1.3 1 0 0 1 1 1 1 Yeast cortical protein KAR9 DNA_photolyase PF00875.13 ETS87931.1 - 0.0088 15.7 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 DNA photolyase Syntaxin-6_N PF09177.6 ETS87931.1 - 0.013 15.9 7.3 2 8.8 0.2 3.9 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF3024 PF11225.3 ETS87931.1 - 0.25 11.2 0.3 0.57 10.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DEAD PF00270.24 ETS87932.1 - 7.5e-20 71.0 0.0 2.1e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 ETS87932.1 - 1.1e-17 63.6 0.0 3.8e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 ETS87932.1 - 1.8e-14 53.2 1.8 4.4e-14 52.0 0.3 2.3 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 ETS87932.1 - 1.8e-05 24.3 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF1275 PF06912.6 ETS87933.1 - 1.4e-47 161.5 15.8 1.6e-47 161.3 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Kinocilin PF15033.1 ETS87933.1 - 0.14 11.6 2.5 0.15 11.5 0.8 1.7 1 1 0 1 1 1 0 Kinocilin protein MFS_1 PF07690.11 ETS87934.1 - 4.6e-26 91.3 34.0 1.3e-20 73.4 6.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.4 ETS87935.1 - 3.6e-22 78.6 2.7 3.6e-22 78.6 1.8 3.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 ETS87935.1 - 6.6e-05 22.4 0.3 0.00015 21.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_BLLF1 PF05109.8 ETS87935.1 - 1.3 6.8 36.8 1.7 6.4 25.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Rifin_STEVOR PF02009.11 ETS87935.1 - 1.8 8.1 5.6 2.4 7.7 3.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family KH_1 PF00013.24 ETS87936.1 - 9.6e-41 137.2 7.2 1.3e-16 59.9 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 ETS87936.1 - 1.3e-30 104.4 14.7 2.6e-11 42.8 2.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 ETS87936.1 - 4.5e-12 45.3 4.4 0.0075 15.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 ETS87936.1 - 6.7e-05 22.4 0.4 0.84 9.3 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 ETS87936.1 - 0.0045 16.7 7.8 0.79 9.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 ETS87937.1 - 1.2e-10 41.0 0.7 0.00015 21.1 1.1 2.2 2 0 0 2 2 2 2 Centromere-associated protein K DUF2004 PF09406.5 ETS87937.1 - 0.0015 18.5 0.6 0.062 13.3 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2004) Peptidase_S49 PF01343.13 ETS87937.1 - 0.073 12.8 0.7 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 Prefoldin_2 PF01920.15 ETS87937.1 - 0.49 10.1 13.3 0.97 9.2 1.1 3.6 3 0 0 3 3 3 0 Prefoldin subunit MAT1 PF06391.8 ETS87937.1 - 1.5 8.3 8.3 0.17 11.4 0.9 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PNPase PF03726.9 ETS87937.1 - 8.8 6.6 8.1 2.8 8.2 0.4 3.3 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Filament PF00038.16 ETS87937.1 - 10 5.5 15.9 1.5 8.2 6.9 2.4 2 1 1 3 3 3 0 Intermediate filament protein dUTPase PF00692.14 ETS87938.1 - 1.6e-42 143.9 0.0 2.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase SSP160 PF06933.6 ETS87938.1 - 2.1 6.2 13.2 2.9 5.7 9.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Phos_pyr_kin PF08543.7 ETS87939.1 - 1.2e-10 41.0 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 ETS87939.1 - 4.3e-09 35.9 2.0 1.4e-07 30.9 0.3 2.6 2 1 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_C PF02747.10 ETS87940.1 - 1.4e-52 176.9 0.0 3.2e-52 175.8 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 ETS87940.1 - 2.1e-51 172.7 4.7 2.1e-51 172.7 3.3 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 ETS87940.1 - 3.3e-11 42.8 0.1 3.8e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 ETS87940.1 - 2.4e-08 33.0 0.8 1.1e-06 27.6 0.6 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 ETS87940.1 - 5e-05 22.4 0.3 0.00067 18.6 0.1 2.1 1 1 1 2 2 2 1 Hus1-like protein Vezatin PF12632.2 ETS87941.1 - 1.7e-18 66.6 3.1 2.5e-18 66.1 2.1 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes SAP PF02037.22 ETS87941.1 - 0.14 11.6 0.7 5.2 6.6 0.0 3.2 3 0 0 3 3 3 0 SAP domain Rab5ip PF07019.7 ETS87942.1 - 5.4e-22 77.7 5.8 6.4e-22 77.4 4.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PspC PF04024.7 ETS87942.1 - 1.6 8.2 4.7 3.6 7.1 0.0 2.8 2 1 0 2 2 2 0 PspC domain GTP_EFTU PF00009.22 ETS87943.1 - 4.8e-08 32.6 0.0 1.5e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 ETS87943.1 - 0.013 15.7 0.1 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 ETS87943.1 - 0.016 14.7 0.4 2 7.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 ETS87943.1 - 0.068 12.8 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 ETS87943.1 - 0.077 11.8 0.2 0.14 11.0 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SNARE PF05739.14 ETS87944.1 - 1.4e-05 24.6 0.9 1.4e-05 24.6 0.7 3.5 4 1 1 5 5 5 1 SNARE domain DUF3072 PF11272.3 ETS87944.1 - 0.96 9.1 7.2 0.24 11.1 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3072) Complex1_LYR PF05347.10 ETS87945.1 - 6.2e-07 29.1 0.2 1.4e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 ETS87945.1 - 1e-05 25.6 1.4 2.4e-05 24.4 0.1 2.2 3 0 0 3 3 3 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 ETS87945.1 - 1.5e-05 25.4 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like OB_NTP_bind PF07717.11 ETS87946.1 - 1.8e-18 66.4 0.0 4.3e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 ETS87946.1 - 1.8e-16 60.0 0.0 4.4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 ETS87946.1 - 1.9e-13 50.0 0.0 6.3e-13 48.4 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 ETS87946.1 - 8.7e-08 31.8 0.0 2.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 ETS87946.1 - 0.0012 19.0 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 ETS87946.1 - 0.0031 17.0 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 ETS87946.1 - 0.0046 17.2 0.1 0.021 15.1 0.0 2.2 3 0 0 3 3 3 1 ABC transporter FtsK_SpoIIIE PF01580.13 ETS87946.1 - 0.008 15.6 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 ETS87946.1 - 0.019 13.8 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 ETS87946.1 - 0.043 13.8 0.7 0.33 10.8 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 ETS87946.1 - 0.082 13.2 0.4 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 ETS87946.1 - 0.084 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 ETS87946.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.6 1 0 0 1 1 1 0 KaiC Methyltransf_16 PF10294.4 ETS87947.1 - 0.0041 16.5 0.0 0.046 13.1 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Pyr_redox_3 PF13738.1 ETS87948.1 - 5.5e-20 72.3 0.0 1.5e-19 70.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 ETS87948.1 - 3.6e-10 38.6 0.0 2.2e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 ETS87948.1 - 1.5e-08 34.5 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 ETS87948.1 - 9.1e-07 28.0 0.0 0.00078 18.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 ETS87948.1 - 0.0018 18.0 0.1 0.047 13.4 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 ETS87948.1 - 0.012 15.5 0.0 0.17 11.7 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.4 ETS87949.1 - 4.7e-14 52.6 2.5 4.7e-14 52.6 1.7 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.5 ETS87949.1 - 0.54 9.8 16.4 0.74 9.4 11.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SpoIIE PF07228.7 ETS87950.1 - 9e-11 41.8 0.1 5.6e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 ETS87950.1 - 5.3e-10 39.1 0.8 0.00042 19.7 0.0 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 ETS87950.1 - 1.3e-08 34.5 0.1 2.3e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Prenyltrans PF00432.16 ETS87950.1 - 0.052 13.1 0.5 0.55 9.8 0.2 2.5 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Fer2_3 PF13085.1 ETS87951.1 - 3.5e-33 113.7 0.0 5.4e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 ETS87951.1 - 3.1e-09 37.0 5.8 3.1e-09 37.0 4.0 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 ETS87951.1 - 5.5e-09 35.9 4.1 5.5e-09 35.9 2.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 ETS87951.1 - 0.00012 22.4 1.4 0.00012 22.4 1.0 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 ETS87951.1 - 0.00013 22.2 3.4 0.031 14.5 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 ETS87951.1 - 0.00025 20.8 6.0 0.00025 20.7 2.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 ETS87951.1 - 0.0014 18.9 4.2 0.0014 18.9 2.9 2.4 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 ETS87951.1 - 0.0023 17.6 3.1 0.0025 17.5 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 ETS87951.1 - 3.3 8.3 6.4 1.2 9.7 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Glyco_transf_9 PF01075.12 ETS87952.1 - 0.039 13.1 0.4 0.066 12.4 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) zf-CCCH PF00642.19 ETS87952.1 - 0.05 13.2 7.4 0.091 12.4 5.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Phage_Mu_Gam PF07352.7 ETS87952.1 - 0.19 11.2 1.4 0.43 10.0 1.0 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein CAP_GLY PF01302.20 ETS87953.1 - 9.6e-21 73.2 0.1 2.7e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.2 ETS87953.1 - 2.4e-15 55.7 6.9 9.1e-05 21.9 0.0 5.4 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 ETS87953.1 - 6.6e-12 45.0 4.5 1.9e-05 24.2 1.4 4.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 ETS87953.1 - 3e-06 26.5 9.2 0.45 10.7 0.0 6.6 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 ETS87953.1 - 0.00027 20.6 6.4 22 5.8 0.1 6.1 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 ETS87953.1 - 0.00078 19.2 9.8 1.6 9.0 0.0 6.5 7 0 0 7 7 7 1 Leucine Rich repeat MaoC_dehydratas PF01575.14 ETS87954.1 - 4.5e-22 77.7 0.0 7.3e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain FMN_dh PF01070.13 ETS87956.1 - 1.4e-103 346.4 0.0 1.8e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 ETS87956.1 - 1e-21 76.4 0.1 5.4e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 ETS87956.1 - 9.6e-07 28.0 0.1 1.4e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 ETS87956.1 - 2.9e-05 23.1 0.1 0.00033 19.6 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 ETS87956.1 - 0.0036 16.8 0.1 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 ETS87956.1 - 0.0095 15.1 0.3 0.017 14.2 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 ETS87956.1 - 0.025 13.8 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 ETS87956.1 - 0.048 12.6 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF3712 PF12505.3 ETS87957.1 - 6.9e-19 68.0 3.4 6.9e-19 68.0 2.4 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF805 PF05656.9 ETS87957.1 - 0.013 15.2 0.2 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Prominin PF05478.6 ETS87957.1 - 0.07 10.6 0.0 0.099 10.1 0.0 1.1 1 0 0 1 1 1 0 Prominin LEA_2 PF03168.8 ETS87957.1 - 0.083 13.2 3.1 5.8 7.3 0.1 3.5 2 2 0 2 2 2 0 Late embryogenesis abundant protein UPF0370 PF13980.1 ETS87957.1 - 0.59 9.9 2.0 1.1 9.1 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) HLH PF00010.21 ETS87958.1 - 7e-13 48.0 1.4 1.8e-12 46.7 1.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1875 PF08961.5 ETS87958.1 - 0.00014 21.2 2.1 0.00024 20.4 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) DUF904 PF06005.7 ETS87958.1 - 0.027 14.7 5.4 1 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) NifQ PF04891.7 ETS87958.1 - 0.12 12.5 3.4 0.2 11.8 2.4 1.3 1 0 0 1 1 1 0 NifQ RRM_1 PF00076.17 ETS87959.1 - 1.2e-38 130.5 0.0 3.7e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS87959.1 - 4.8e-30 103.3 0.0 1.6e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS87959.1 - 4.2e-14 52.1 0.0 2.3e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 ETS87959.1 - 0.0067 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TPR_1 PF00515.23 ETS87960.1 - 3.1e-23 80.3 2.3 6.7e-08 31.8 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 ETS87960.1 - 9.1e-23 79.6 8.5 1.1e-10 41.0 0.5 4.4 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 ETS87960.1 - 1.3e-20 71.5 7.4 5.2e-06 25.9 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 ETS87960.1 - 6.6e-15 54.2 9.5 0.00014 22.1 0.1 6.7 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 ETS87960.1 - 1.1e-14 54.6 9.9 6.3e-07 29.9 0.1 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 ETS87960.1 - 8.2e-14 51.7 2.5 0.00032 20.9 0.8 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 ETS87960.1 - 1.1e-12 47.0 1.8 0.026 14.6 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 ETS87960.1 - 4.6e-12 45.7 7.9 2.4e-08 33.7 0.2 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS87960.1 - 1.2e-10 40.3 2.6 0.003 17.2 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 ETS87960.1 - 4.4e-09 36.0 1.8 0.00059 19.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 ETS87960.1 - 1.2e-08 34.0 0.6 0.00081 19.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 ETS87960.1 - 1.7e-08 34.4 2.4 0.026 14.6 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 ETS87960.1 - 2.5e-06 27.5 1.6 0.0054 16.8 0.3 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 ETS87960.1 - 0.00093 19.0 2.1 3.9 7.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat HlyD PF00529.15 ETS87960.1 - 0.0032 16.8 1.2 0.0032 16.8 0.9 2.2 3 0 0 3 3 3 1 HlyD family secretion protein MIT PF04212.13 ETS87960.1 - 0.0035 17.1 3.1 12 5.8 0.8 4.7 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 ETS87960.1 - 0.0045 16.7 0.2 6 6.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 ETS87960.1 - 0.0057 17.0 11.1 8.5 7.0 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DED PF01335.16 ETS87960.1 - 0.048 13.7 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Death effector domain RNase_T PF00929.19 ETS87961.1 - 3.9e-23 82.5 0.0 7.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF1664 PF07889.7 ETS87962.1 - 0.00014 21.6 0.9 0.00014 21.6 0.6 6.2 2 1 5 7 7 7 2 Protein of unknown function (DUF1664) Apolipoprotein PF01442.13 ETS87962.1 - 0.065 12.7 49.7 0.031 13.8 10.9 4.6 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain DUF3584 PF12128.3 ETS87962.1 - 0.29 8.4 53.5 0.016 12.6 10.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) WEMBL PF05701.6 ETS87962.1 - 0.33 9.3 53.6 0.37 9.2 20.9 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Rootletin PF15035.1 ETS87962.1 - 0.44 10.5 59.5 0.25 11.2 11.0 4.2 2 2 3 5 5 5 0 Ciliary rootlet component, centrosome cohesion DUF2580 PF10824.3 ETS87962.1 - 1.4 9.3 11.8 2.9 8.2 0.3 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2580) HAUS-augmin3 PF14932.1 ETS87962.1 - 1.9 7.6 44.6 2.7 7.1 6.6 4.2 1 1 1 4 4 4 0 HAUS augmin-like complex subunit 3 Lectin_N PF03954.9 ETS87962.1 - 4.4 6.6 28.1 0.48 9.8 2.0 5.7 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 ETS87962.1 - 8.8 6.6 15.4 0.42 10.8 0.1 5.1 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein zf-MYND PF01753.13 ETS87963.1 - 8.6e-10 38.3 11.9 8.6e-10 38.3 8.2 2.1 2 0 0 2 2 2 1 MYND finger SET PF00856.23 ETS87963.1 - 3.2e-07 30.7 0.0 8.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 SET domain Dioxygenase_C PF00775.16 ETS87964.1 - 3.6e-07 29.6 0.1 7.2e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 ETS87965.1 - 1.1e-33 117.3 6.6 2.7e-33 115.9 4.6 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Acetyltransf_10 PF13673.1 ETS87966.1 - 0.056 13.5 0.2 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FolB PF02152.13 ETS87967.1 - 9.6e-17 61.1 0.0 8.7e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase DUF3605 PF12239.3 ETS87968.1 - 2.4e-58 196.4 1.0 2.9e-58 196.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.13 ETS87969.1 - 5.2e-184 611.6 0.2 6e-184 611.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 ETS87969.1 - 0.009 14.6 0.5 0.15 10.6 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4301) Phage_prot_Gp6 PF05133.9 ETS87969.1 - 0.026 13.1 0.1 0.041 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like ING PF12998.2 ETS87970.1 - 1.1e-17 64.2 1.4 1.5e-17 63.7 1.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 ETS87970.1 - 7.4e-09 35.1 9.6 7.4e-09 35.1 6.6 1.8 2 0 0 2 2 2 1 PHD-finger Hist_deacetyl PF00850.14 ETS87971.1 - 4e-79 266.1 0.1 5.9e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.11 ETS87972.1 - 1.3e-18 66.8 9.2 1.3e-18 66.8 6.3 2.4 1 1 1 3 3 3 1 Major Facilitator Superfamily Apolipoprotein PF01442.13 ETS87972.1 - 0.0053 16.2 0.1 0.0076 15.7 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SUN PF03856.8 ETS87973.1 - 3.2e-86 288.6 12.8 4.5e-86 288.1 8.9 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Alpha_GJ PF03229.8 ETS87973.1 - 0.87 9.9 14.9 0.4 11.0 8.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J AF-4 PF05110.8 ETS87973.1 - 0.95 7.2 10.9 1.2 6.8 7.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.4 ETS87973.1 - 1.9 6.6 4.9 2.3 6.3 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_16 PF00722.16 ETS87974.1 - 6.5e-12 45.1 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-H2C2_2 PF13465.1 ETS87975.1 - 1.3e-13 50.5 19.3 6.7e-08 32.4 1.8 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 ETS87975.1 - 2.1e-10 40.3 22.8 0.004 17.4 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS87975.1 - 1.2e-07 31.4 20.3 0.0081 16.4 4.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Vps5 PF09325.5 ETS87975.1 - 0.0056 15.9 0.1 0.0087 15.3 0.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like zf-C2H2_6 PF13912.1 ETS87975.1 - 0.011 15.6 12.0 0.42 10.5 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger PyrI_C PF02748.10 ETS87975.1 - 0.041 13.3 0.0 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 ETS87975.1 - 0.048 13.7 11.2 0.22 11.6 4.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 ETS87975.1 - 0.19 11.6 6.8 1.6 8.6 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger domain zf-RING_3 PF14369.1 ETS87975.1 - 0.48 10.4 4.8 9.7 6.2 0.1 2.9 2 1 0 2 2 2 0 zinc-finger zf-CHY PF05495.7 ETS87975.1 - 0.56 10.4 7.2 1.3 9.2 5.0 1.6 1 0 0 1 1 1 0 CHY zinc finger GAGA PF09237.6 ETS87975.1 - 0.85 9.2 6.2 0.8 9.3 0.3 2.8 1 1 2 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.3 ETS87975.1 - 0.93 9.7 12.6 1.3 9.2 2.9 3.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 ETS87975.1 - 2 8.3 6.8 24 4.8 4.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon Striatin PF08232.7 ETS87975.1 - 2 8.7 6.8 0.16 12.2 0.6 2.2 2 0 0 2 2 1 0 Striatin family zf-C2HC_2 PF13913.1 ETS87975.1 - 2.5 7.8 8.0 0.087 12.5 0.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_S19 PF00203.16 ETS87976.1 - 1.3e-33 114.4 0.3 2e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 V-ATPase_H_N PF03224.9 ETS87978.1 - 0.067 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Herpes_US9 PF06072.6 ETS87979.1 - 0.45 10.3 1.5 1.1 9.1 1.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ribosomal_60s PF00428.14 ETS87980.1 - 0.12 12.8 7.7 1.3 9.4 0.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein NUDIX PF00293.23 ETS87981.1 - 9.4e-15 54.4 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ctr PF04145.10 ETS87982.1 - 2.7e-36 124.7 5.4 3.2e-36 124.5 3.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4190 PF13828.1 ETS87982.1 - 0.1 12.1 1.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF962 PF06127.6 ETS87982.1 - 0.63 9.9 4.2 0.68 9.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF962) 3-HAO PF06052.7 ETS87983.1 - 4.3e-64 214.4 0.0 4.9e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 ETS87983.1 - 9.4e-07 28.2 0.1 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 ETS87983.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 ETS87983.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_4 PF08007.7 ETS87983.1 - 0.16 11.1 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein DZR PF12773.2 ETS87983.1 - 0.2 11.4 2.1 0.4 10.5 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-CCHC_6 PF15288.1 ETS87983.1 - 0.25 11.0 2.0 0.45 10.2 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 ETS87984.1 - 7.2e-76 254.7 0.0 1.1e-75 254.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS87984.1 - 7.4e-37 126.8 0.0 9.9e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 ETS87984.1 - 4.7e-18 65.0 0.3 1.2e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 ETS87984.1 - 7.1e-10 38.3 0.0 6.4e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 ETS87984.1 - 0.0014 17.5 0.1 0.0027 16.5 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 ETS87984.1 - 0.0041 16.2 0.1 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 ETS87984.1 - 0.13 12.0 0.0 0.68 9.6 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family ArfGap PF01412.13 ETS87985.1 - 1.7e-33 114.8 0.0 6e-33 113.1 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 ETS87985.1 - 2.1e-12 47.1 0.1 5.1e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 PH domain TF_Zn_Ribbon PF08271.7 ETS87985.1 - 0.16 11.3 0.2 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding EMP24_GP25L PF01105.19 ETS87985.1 - 0.45 10.2 3.1 0.86 9.2 1.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Membr_traf_MHD PF10540.4 ETS87986.1 - 2.8e-22 79.0 0.1 8.4e-22 77.4 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 ETS87986.1 - 1.4e-18 66.4 0.0 3.8e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 ETS87986.1 - 7.9e-05 21.1 0.1 0.00012 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF810) HAMP PF00672.20 ETS87987.1 - 2.4e-48 162.1 16.7 8.9e-09 35.4 0.1 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 ETS87987.1 - 7.3e-30 102.9 0.1 2e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 ETS87987.1 - 5.5e-29 100.4 3.7 7.3e-27 93.5 0.2 3.1 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 ETS87987.1 - 6e-18 64.5 0.4 6e-18 64.5 0.3 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 ETS87987.1 - 2.2e-06 26.4 9.3 0.01 14.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain Pox_A_type_inc PF04508.7 ETS87987.1 - 0.0021 17.6 0.8 0.44 10.4 0.1 4.8 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat DUF2365 PF10157.4 ETS87987.1 - 0.01 15.7 13.4 3.1 7.6 0.0 6.8 5 1 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) HMG_box PF00505.14 ETS87988.1 - 6.9e-11 42.2 0.8 1.2e-10 41.5 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 ETS87988.1 - 5.7e-10 39.4 0.9 9e-10 38.7 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain Unstab_antitox PF09720.5 ETS87988.1 - 0.09 12.4 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative addiction module component HMG_box_5 PF14887.1 ETS87988.1 - 0.7 9.7 4.8 2.3 8.0 0.6 2.2 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Cnd2 PF05786.9 ETS87989.1 - 7.2e-207 689.3 9.7 8.5e-207 689.0 6.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Gag_p15 PF08723.5 ETS87989.1 - 0.11 12.4 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Gag protein p15 Na_Ca_ex PF01699.19 ETS87990.1 - 3.8e-33 114.0 32.2 1.8e-24 85.9 9.9 3.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3810 PF12725.2 ETS87990.1 - 0.22 10.3 0.2 0.5 9.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WW PF00397.21 ETS87992.1 - 1.6e-09 37.4 1.2 3.1e-09 36.5 0.1 2.2 2 0 0 2 2 2 1 WW domain PhoD PF09423.5 ETS87992.1 - 0.014 13.9 0.3 0.053 12.0 0.1 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase HSP20 PF00011.16 ETS87993.1 - 2.1e-10 40.3 0.1 3.7e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pcc1 PF09341.5 ETS87994.1 - 9.2e-26 89.7 0.4 1.5e-25 88.9 0.3 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 ETS87995.1 - 6.9e-44 149.2 0.0 4.2e-40 137.0 0.0 3.3 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 ETS87995.1 - 4.5e-16 58.6 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 ETS87995.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 ETS87995.1 - 0.065 13.2 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate COesterase PF00135.23 ETS87996.1 - 1.9e-85 287.6 0.0 2.4e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 ETS87996.1 - 4.6e-06 26.3 0.2 1e-05 25.2 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.21 ETS87997.1 - 4e-13 48.8 11.5 6e-07 29.4 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS87997.1 - 8.4e-10 38.2 10.0 0.0004 20.5 3.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 ETS87997.1 - 2.4e-05 24.3 3.9 0.0026 17.9 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 ETS87997.1 - 0.00026 21.1 14.5 0.00035 20.7 4.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 ETS87997.1 - 0.0015 18.6 6.7 0.03 14.4 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS87997.1 - 0.025 14.4 0.3 0.025 14.4 0.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.17 ETS87997.1 - 0.95 9.5 4.2 1.8 8.6 2.9 1.5 1 0 0 1 1 1 0 LIM domain zf-trcl PF13451.1 ETS87997.1 - 1 9.0 4.2 0.79 9.4 0.3 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain ATP_bind_4 PF01902.12 ETS87998.1 - 4.6e-21 75.2 0.0 2.2e-08 33.7 0.0 4.0 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 ETS87998.1 - 2.8e-07 30.3 0.3 0.0012 18.6 0.0 4.5 4 1 0 4 4 4 2 Endoribonuclease L-PSP Prophage_tail PF06605.6 ETS87998.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail DUF202 PF02656.10 ETS87999.1 - 3.9e-25 87.8 1.5 3.9e-25 87.8 1.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B_N PF00033.14 ETS87999.1 - 0.019 14.3 3.2 0.029 13.7 2.2 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Rax2 PF12768.2 ETS87999.1 - 0.18 10.9 1.5 0.32 10.1 1.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity AAA_11 PF13086.1 ETS88000.1 - 3.4e-58 197.0 0.2 1e-57 195.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 ETS88000.1 - 9.1e-48 162.2 0.0 9.2e-47 159.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 ETS88000.1 - 1.1e-13 50.6 0.1 1.4e-12 47.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 ETS88000.1 - 1.7e-10 40.8 0.0 1.2e-08 34.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 ETS88000.1 - 6.5e-08 31.9 0.2 3.3e-07 29.6 0.2 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 ETS88000.1 - 6.9e-08 32.5 0.0 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 ETS88000.1 - 6.9e-06 25.5 0.1 1.8e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 ETS88000.1 - 3.8e-05 23.8 0.1 0.0012 18.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 ETS88000.1 - 0.00034 20.2 0.0 0.58 9.6 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 ETS88000.1 - 0.00097 18.6 0.0 0.0062 16.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 ETS88000.1 - 0.0012 18.1 0.0 0.041 13.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 ETS88000.1 - 0.0014 18.0 0.0 0.0059 16.0 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein Flavi_DEAD PF07652.9 ETS88000.1 - 0.0017 18.1 0.1 0.016 14.9 0.0 2.4 2 0 0 2 2 2 1 Flavivirus DEAD domain Zot PF05707.7 ETS88000.1 - 0.0021 17.5 0.1 0.019 14.4 0.0 2.5 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) Helicase_RecD PF05127.9 ETS88000.1 - 0.0023 17.6 0.0 0.043 13.4 0.0 2.4 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 ETS88000.1 - 0.004 16.5 0.1 0.034 13.5 0.0 2.3 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.1 ETS88000.1 - 0.0047 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 ETS88000.1 - 0.0051 15.7 0.0 0.0097 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 ETS88000.1 - 0.013 15.7 0.1 0.15 12.2 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 ETS88000.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 ETS88000.1 - 0.013 14.0 0.0 0.027 13.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 ETS88000.1 - 0.048 13.3 0.1 0.4 10.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B 4HB_MCP_1 PF12729.2 ETS88000.1 - 0.057 12.7 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction FtsK_SpoIIIE PF01580.13 ETS88000.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 ETS88000.1 - 0.076 13.3 0.1 0.31 11.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter CbiA PF01656.18 ETS88000.1 - 0.084 12.2 1.4 0.36 10.2 0.3 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C PF13361.1 ETS88000.1 - 0.098 12.0 0.1 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 ETS88000.1 - 0.11 13.2 1.3 0.34 11.7 0.3 2.4 2 1 0 2 2 1 0 AAA domain Ribosomal_L30_N PF08079.7 ETS88000.1 - 0.23 11.4 3.8 0.53 10.3 2.7 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain MbeD_MobD PF04899.7 ETS88001.1 - 0.032 14.1 0.2 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 MbeD/MobD like NACHT PF05729.7 ETS88002.1 - 1.7e-08 34.2 0.0 7.5e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 ETS88002.1 - 0.0012 18.8 2.0 0.0054 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 ETS88002.1 - 0.0053 16.8 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 ETS88002.1 - 0.011 14.7 0.6 0.27 10.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain zf-MYND PF01753.13 ETS88003.1 - 3.4e-09 36.4 17.0 3.4e-09 36.4 11.8 1.6 2 0 0 2 2 2 1 MYND finger DUF2235 PF09994.4 ETS88004.1 - 1.7e-67 227.7 0.0 2.1e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_47 PF01532.15 ETS88005.1 - 3.2e-168 560.0 0.0 3.8e-168 559.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 ETS88005.1 - 0.024 12.9 0.0 0.83 7.8 0.0 2.4 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) SHR3_chaperone PF08229.6 ETS88006.1 - 1.5e-71 239.3 0.0 1.7e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 UDG PF03167.14 ETS88006.1 - 0.069 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily EphA2_TM PF14575.1 ETS88007.1 - 0.0013 19.1 0.1 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 ETS88007.1 - 0.0017 17.9 2.2 0.0039 16.7 1.5 1.6 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.8 ETS88007.1 - 0.0027 18.0 14.3 0.0027 18.0 9.9 2.8 2 1 1 3 3 3 1 Alphavirus glycoprotein J Syndecan PF01034.15 ETS88007.1 - 0.0027 17.3 0.2 0.0053 16.3 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Rifin_STEVOR PF02009.11 ETS88007.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF1180 PF06679.7 ETS88007.1 - 0.012 15.4 0.9 0.025 14.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1191 PF06697.7 ETS88007.1 - 0.013 14.3 0.1 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 ETS88007.1 - 0.068 12.4 6.1 0.18 11.1 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 ETS88007.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4328 PF14219.1 ETS88007.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) TMEM154 PF15102.1 ETS88007.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Fungal_trans_2 PF11951.3 ETS88008.1 - 4.3e-77 259.2 0.0 5.4e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS88008.1 - 1.9e-06 27.6 9.1 3.2e-06 26.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 ETS88009.1 - 1e-07 31.7 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 ETS88009.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 ETS88009.1 - 0.0008 19.5 0.1 0.013 15.7 0.0 2.8 2 2 0 2 2 2 1 PH domain Ste50p-SAM PF09235.5 ETS88009.1 - 0.044 13.8 0.1 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.11 ETS88009.1 - 0.049 13.4 0.2 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Sod_Fe_C PF02777.13 ETS88010.1 - 2.2e-12 46.7 0.0 0.00014 21.6 0.0 3.0 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Zn_clus PF00172.13 ETS88011.1 - 0.00031 20.5 12.2 0.00031 20.5 8.5 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.14 ETS88012.1 - 9.7e-20 70.2 7.4 1.4e-19 69.7 5.1 1.2 1 0 0 1 1 1 1 WSC domain AAA PF00004.24 ETS88013.1 - 8.1e-18 64.8 0.1 3.5e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 ETS88013.1 - 0.00035 20.7 0.3 0.013 15.5 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 ETS88013.1 - 0.0006 19.4 1.1 0.00095 18.7 0.3 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 ETS88013.1 - 0.00064 19.6 0.1 0.037 13.9 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 ETS88013.1 - 0.00072 19.5 0.0 0.0048 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 ETS88013.1 - 0.0026 17.4 0.1 0.0089 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 ETS88013.1 - 0.005 17.6 0.0 0.018 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS88013.1 - 0.011 16.0 0.3 0.034 14.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 ETS88013.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 ETS88013.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 ETS88013.1 - 0.03 14.4 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Zot PF05707.7 ETS88013.1 - 0.037 13.4 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ArgK PF03308.11 ETS88013.1 - 0.037 12.7 0.0 0.057 12.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 ETS88013.1 - 0.13 11.7 0.3 1.1 8.5 0.1 2.7 2 1 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 ETS88013.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 ETS88013.1 - 0.16 11.3 1.7 0.28 10.5 0.1 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.1 ETS88013.1 - 0.62 10.3 3.2 0.49 10.6 0.7 2.0 2 1 0 2 2 1 0 AAA domain DivIC PF04977.10 ETS88014.1 - 0.03 13.7 2.1 0.033 13.6 0.3 1.9 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M3 PF01432.15 ETS88015.1 - 1.4e-121 406.7 0.0 1.8e-121 406.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.4 ETS88015.1 - 0.0005 19.2 0.1 0.0047 16.0 0.0 2.2 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF3123 PF11321.3 ETS88015.1 - 0.024 14.8 0.1 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Peptidase_M91 PF14891.1 ETS88015.1 - 0.029 14.4 3.4 3.8 7.5 0.2 2.8 3 0 0 3 3 3 0 Effector protein Peptidase_M50B PF13398.1 ETS88015.1 - 0.22 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 ETS88016.1 - 3e-44 150.4 0.0 6.5e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Mito_carr PF00153.22 ETS88017.1 - 4.3e-65 215.4 3.1 4.6e-22 77.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1b PF00579.20 ETS88019.1 - 9.7e-61 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) IMS PF00817.15 ETS88020.1 - 1e-38 132.4 0.0 2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 ETS88020.1 - 5.6e-16 58.6 0.0 1.2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 ETS88020.1 - 5.6e-13 48.7 5.6 1.7e-07 31.1 1.0 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 ETS88020.1 - 5.8e-05 22.9 0.9 0.00074 19.4 0.0 3.0 3 0 0 3 3 3 1 IMS family HHH motif BRCT PF00533.21 ETS88020.1 - 0.0007 19.7 0.0 0.0034 17.4 0.0 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 ETS88020.1 - 0.001 19.2 0.1 0.0064 16.6 0.1 2.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain MgtE_N PF03448.12 ETS88020.1 - 0.0048 17.1 3.7 3.6 7.9 0.0 4.6 4 0 0 4 4 4 1 MgtE intracellular N domain PTCB-BRCT PF12738.2 ETS88020.1 - 0.032 14.0 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain RED_N PF07808.8 ETS88021.1 - 7.9e-09 35.0 7.2 7.9e-09 35.0 5.0 2.1 2 1 0 2 2 2 1 RED-like protein N-terminal region IU_nuc_hydro PF01156.14 ETS88022.1 - 2.6e-81 273.2 0.0 3e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4286 PF14114.1 ETS88023.1 - 1.1e-05 25.5 0.0 0.00044 20.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) EthD PF07110.6 ETS88023.1 - 0.0018 19.1 0.0 0.25 12.3 0.0 2.3 2 0 0 2 2 2 1 EthD domain Mvb12 PF09452.5 ETS88023.1 - 0.088 12.9 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Mago-bind PF09282.5 ETS88024.1 - 1.7e-13 49.8 3.2 3.3e-13 48.9 2.2 1.5 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 ETS88024.1 - 0.55 10.0 14.3 0.72 9.7 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 ETS88024.1 - 0.65 9.1 9.1 0.88 8.6 6.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF913 PF06025.7 ETS88024.1 - 0.71 8.5 4.3 0.94 8.1 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.12 ETS88024.1 - 1.8 8.3 6.4 2.3 7.9 4.5 1.2 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.6 ETS88024.1 - 2.6 6.2 13.9 3 5.9 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Menin PF05053.8 ETS88024.1 - 4.1 5.4 6.8 4.5 5.3 4.7 1.1 1 0 0 1 1 1 0 Menin MRL1 PF13003.2 ETS88024.1 - 8.7 6.1 7.5 25 4.6 5.2 1.8 1 1 0 1 1 1 0 Ribosomal protein L1 V_ATPase_I PF01496.14 ETS88024.1 - 9.2 3.9 5.7 11 3.7 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UCR_UQCRX_QCR9 PF05365.7 ETS88025.1 - 3e-17 61.9 0.7 3.3e-17 61.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 ETS88026.1 - 4.1e-18 64.8 14.7 5.3e-18 64.5 8.2 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 ETS88026.1 - 2.2e-07 30.5 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 ETS88026.1 - 0.0018 18.0 4.3 0.0018 18.0 3.0 4.2 4 1 0 4 4 4 1 Ring finger domain CAP_N PF01213.14 ETS88026.1 - 0.58 9.3 4.1 1.2 8.3 2.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Exo_endo_phos PF03372.18 ETS88027.1 - 2.9e-20 73.2 0.6 4e-20 72.7 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 ETS88028.1 - 1.8e-58 192.4 19.2 2.5e-12 46.1 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 ETS88028.1 - 9.8e-07 28.6 0.0 0.02 14.5 0.0 3.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETS88028.1 - 0.0004 19.2 1.5 0.0074 15.0 0.0 3.0 2 2 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 ETS88028.1 - 0.025 12.8 0.2 3.5 5.8 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain Secretin_N_2 PF07655.8 ETS88028.1 - 7.8 6.9 28.4 0.19 12.1 4.6 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.20 ETS88029.1 - 3.6e-51 173.8 0.0 6.4e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 ETS88029.1 - 5.4e-24 84.6 0.0 2.4e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 ETS88029.1 - 0.0053 16.5 0.8 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 ETS88029.1 - 0.016 14.1 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 ETS88029.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FKBP_C PF00254.23 ETS88030.1 - 1.1e-31 108.6 0.1 3.4e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIF_alpha PF05793.7 ETS88030.1 - 6.7 4.9 59.7 0.075 11.3 17.7 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 ETS88030.1 - 9.5 4.2 39.6 3 5.8 12.6 2.1 2 0 0 2 2 2 0 Utp14 protein DUF4066 PF13278.1 ETS88031.1 - 7.4e-10 38.3 0.0 1.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 ETS88031.1 - 1.3e-07 31.2 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_trans_2_3 PF13632.1 ETS88032.1 - 1e-17 64.4 0.6 2.3e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FimP PF09766.4 ETS88033.1 - 1e-27 97.2 12.9 1.2e-27 96.9 8.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 ETS88033.1 - 0.0024 17.6 0.2 0.0024 17.6 0.1 3.0 2 1 1 3 3 3 1 K-box region SusD PF07980.6 ETS88033.1 - 0.074 12.5 1.4 0.11 12.0 1.0 1.2 1 0 0 1 1 1 0 SusD family CENP-F_leu_zip PF10473.4 ETS88033.1 - 0.096 12.5 13.6 1.6 8.6 4.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BBS2_C PF14782.1 ETS88033.1 - 0.51 8.8 10.5 0.018 13.6 0.8 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Cortex-I_coil PF09304.5 ETS88033.1 - 1.9 8.5 13.1 0.94 9.5 3.6 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil FtsL PF04999.8 ETS88033.1 - 5.6 6.7 6.5 0.79 9.4 1.3 2.0 2 0 0 2 2 2 0 Cell division protein FtsL HlyIII PF03006.15 ETS88034.1 - 1.5e-59 201.1 19.8 1.8e-59 200.8 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 ETS88034.1 - 0.02 14.6 0.8 0.056 13.2 0.5 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.8 ETS88034.1 - 0.056 12.4 2.5 0.085 11.8 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) EspB PF05802.6 ETS88034.1 - 0.15 10.9 1.2 0.26 10.1 0.7 1.4 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF883 PF05957.8 ETS88034.1 - 0.33 11.3 10.3 0.92 9.9 1.8 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 ETS88034.1 - 1.5 9.3 9.4 1.7 9.0 1.8 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term YfhO PF09586.5 ETS88034.1 - 7.3 4.4 8.9 9.4 4.1 6.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RabGAP-TBC PF00566.13 ETS88036.1 - 1.5e-30 106.2 0.0 2.9e-25 89.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 ETS88037.1 - 1.7e-70 237.2 10.5 2.9e-70 236.4 7.3 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 ETS88037.1 - 4e-31 106.5 3.5 4e-31 106.5 2.4 3.8 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 ETS88037.1 - 9.5e-09 34.7 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 ETS88037.1 - 2.2 8.0 9.0 0.15 11.7 1.4 2.9 2 0 0 2 2 2 0 Stannin transmembrane SWIM PF04434.12 ETS88038.1 - 0.017 14.6 0.1 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 SWIM zinc finger Glyco_hydro_16 PF00722.16 ETS88039.1 - 2.6e-13 49.6 0.0 7.4e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.7 ETS88041.1 - 2.5e-65 220.3 3.2 3.3e-65 219.9 2.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Fungal_trans PF04082.13 ETS88043.1 - 3.9e-13 48.8 0.0 6.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS88043.1 - 2.9e-08 33.4 7.9 5.3e-08 32.6 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 ETS88043.1 - 0.019 13.8 8.3 0.038 12.8 5.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor URO-D PF01208.12 ETS88045.1 - 2.9e-115 384.8 0.0 3.3e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FR47 PF08445.5 ETS88046.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 ETS88046.1 - 0.00038 20.6 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS88046.1 - 0.014 15.5 0.0 0.054 13.6 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 ETS88046.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 ETS88046.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 ETS88046.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF3602 PF12223.3 ETS88047.1 - 5e-18 65.2 12.8 3.9e-15 55.9 0.9 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Velvet PF11754.3 ETS88048.1 - 1.5e-68 230.4 0.0 2e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Velvet factor RhoGEF PF00621.15 ETS88049.1 - 1.2e-32 113.1 1.5 1.6e-32 112.8 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 ETS88049.1 - 3e-10 39.9 1.9 3e-10 39.9 1.3 3.0 3 0 0 3 3 3 1 BAR domain Telomerase_RBD PF12009.3 ETS88050.1 - 1.8e-41 141.2 0.8 3.9e-41 140.1 0.5 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 ETS88050.1 - 1.6e-16 60.2 0.0 2e-15 56.7 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MT PF12777.2 ETS88050.1 - 0.056 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor MFS_2 PF13347.1 ETS88051.1 - 3.7e-13 48.6 10.0 3.7e-13 48.6 7.0 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 ETS88051.1 - 5.7e-05 22.0 3.4 0.00011 21.0 2.3 1.4 1 0 0 1 1 1 1 PUCC protein MFS_1_like PF12832.2 ETS88051.1 - 0.0045 16.7 2.0 0.13 12.0 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family DUF1228 PF06779.9 ETS88051.1 - 5.5 7.0 11.3 1.5 8.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) HisG PF01634.13 ETS88052.1 - 8.6e-51 171.7 0.8 2.3e-40 137.8 0.1 2.2 1 1 1 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 ETS88052.1 - 8.1e-26 89.7 0.3 1.7e-25 88.7 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain BCHF PF07284.6 ETS88053.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) MBOAT_2 PF13813.1 ETS88054.1 - 3.3e-18 65.5 4.9 3.3e-18 65.5 3.4 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 7tm_2 PF00002.19 ETS88055.1 - 1.3e-05 24.4 14.6 2.9e-05 23.2 10.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cellulase PF00150.13 ETS88056.1 - 2.4e-37 128.6 0.0 2.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_15 PF00723.16 ETS88057.1 - 7.9e-53 179.6 0.0 1.1e-47 162.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 F-box-like PF12937.2 ETS88058.1 - 0.00013 21.5 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 ETS88058.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain Bromo_TP PF07524.8 ETS88059.1 - 9.5e-06 25.2 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF2164 PF09932.4 ETS88059.1 - 0.0031 17.2 0.0 0.0083 15.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2164) TAFII55_N PF04658.8 ETS88060.1 - 2.1e-44 150.8 0.1 3.8e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region CENP-T PF15511.1 ETS88060.1 - 0.0066 15.7 32.8 0.054 12.7 16.2 2.2 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T ParBc_2 PF08857.6 ETS88060.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Putative ParB-like nuclease DUF3450 PF11932.3 ETS88060.1 - 0.023 13.9 2.4 0.039 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cwf_Cwc_15 PF04889.7 ETS88060.1 - 0.5 10.0 27.9 0.047 13.4 7.3 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L37 PF08561.5 ETS88061.1 - 6.5e-28 96.1 4.9 3.8e-21 74.4 0.3 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 ETS88062.1 - 0.00052 20.1 0.1 0.0006 19.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 ETS88062.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.17 ETS88063.1 - 2.9e-38 129.3 0.9 2.1e-18 65.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS88063.1 - 1.2e-27 95.6 0.0 1.9e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS88063.1 - 3.9e-08 33.0 0.0 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 ETS88063.1 - 0.00068 18.2 43.5 0.00088 17.8 30.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SET_assoc PF11767.3 ETS88063.1 - 0.19 11.0 0.1 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF605 PF04652.11 ETS88063.1 - 0.2 11.0 35.0 0.31 10.3 24.3 1.2 1 0 0 1 1 1 0 Vta1 like DUF1752 PF08550.5 ETS88064.1 - 1.6e-07 30.7 6.0 3e-07 29.8 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.11 ETS88065.1 - 2.6e-76 255.6 0.0 3.5e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 ETS88065.1 - 0.068 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 ETS88066.1 - 7.1e-28 97.7 0.0 1.3e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.14 ETS88067.1 - 1.2e-07 31.1 0.0 2.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Herpes_US12 PF05363.7 ETS88067.1 - 0.0026 18.2 0.7 12 6.5 0.2 3.2 3 0 0 3 3 3 2 Herpesvirus US12 family Rad10 PF03834.9 ETS88067.1 - 0.17 11.6 0.7 0.4 10.4 0.5 1.7 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Sec10 PF07393.6 ETS88068.1 - 9e-221 734.8 0.9 1.1e-220 734.6 0.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Hpt PF01627.18 ETS88068.1 - 0.036 14.0 1.5 1.5 8.8 0.0 3.5 2 0 0 2 2 2 0 Hpt domain DUF1564 PF07600.6 ETS88068.1 - 0.051 12.9 0.9 0.12 11.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) Homeobox PF00046.24 ETS88069.1 - 1.6e-14 53.2 2.1 4.3e-14 51.8 1.4 1.8 1 0 0 1 1 1 1 Homeobox domain NAD_kinase PF01513.16 ETS88070.1 - 2e-71 240.1 0.0 3.3e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 ETS88071.1 - 2.5e-12 47.2 0.1 7.5e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 3' exoribonuclease family, domain 1 HrpF PF06266.7 ETS88071.1 - 0.013 15.6 2.3 1.5 9.0 0.0 2.4 1 1 1 2 2 2 0 HrpF protein RNase_PH_C PF03725.10 ETS88071.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.10 ETS88072.1 - 9e-113 376.3 0.0 1.1e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Rod-binding PF10135.4 ETS88072.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Rod binding protein Glyco_hydro_2_C PF02836.12 ETS88073.1 - 2.5e-99 331.9 0.0 3.4e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 ETS88073.1 - 1.5e-60 204.5 0.0 3e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 ETS88073.1 - 2.9e-54 183.0 0.8 9e-54 181.5 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 ETS88073.1 - 2.4e-13 50.4 0.0 7.8e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 ETS88073.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Erg28 PF03694.8 ETS88074.1 - 1.6e-18 66.7 0.1 1.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein IBR PF01485.16 ETS88075.1 - 1.4e-10 40.8 6.9 1.4e-10 40.8 4.8 4.1 3 1 1 4 4 4 2 IBR domain OPT PF03169.10 ETS88076.1 - 2.7e-180 600.9 59.2 3.1e-180 600.7 41.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 ETS88076.1 - 0.36 9.8 0.8 1.3 7.9 0.6 2.0 1 0 0 1 1 1 0 E1-E2 ATPase CorA PF01544.13 ETS88077.1 - 1.1e-08 34.4 0.5 1.1e-08 34.4 0.4 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 ETS88078.1 - 3.7e-42 144.4 17.7 5.1e-42 143.9 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 ETS88078.1 - 1.3e-33 116.2 29.4 1.5e-33 115.9 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 ETS88078.1 - 0.00019 21.1 0.6 0.037 13.8 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family Aldolase_II PF00596.16 ETS88080.1 - 1.6e-45 154.9 0.2 1.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TauD PF02668.11 ETS88081.1 - 3.1e-50 171.2 0.0 4.5e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 ETS88081.1 - 0.12 12.9 0.3 0.8 10.2 0.0 2.3 2 1 1 3 3 3 0 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.3 ETS88082.1 - 6e-15 54.7 7.5 1e-11 44.0 1.8 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS88082.1 - 1.3e-07 31.3 11.8 3.3e-07 30.1 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 ETS88083.1 - 0.033 13.8 0.3 0.091 12.5 0.2 1.8 1 0 0 1 1 1 0 F-box-like DIOX_N PF14226.1 ETS88084.1 - 1.1e-25 90.4 0.0 1.5e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 ETS88084.1 - 5.4e-19 68.3 0.0 8.3e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 ETS88085.1 - 9.7e-47 159.5 14.4 1.2e-46 159.1 10.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OPT PF03169.10 ETS88086.1 - 1.2e-125 420.4 48.3 1.4e-125 420.1 33.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CorA PF01544.13 ETS88087.1 - 2.4e-06 26.8 1.3 1.6e-05 24.1 0.2 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 ETS88088.1 - 2.2e-21 76.1 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS88088.1 - 2.3e-07 30.1 0.0 4.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 ETS88089.1 - 1.5e-25 89.8 0.0 2.9e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 ETS88089.1 - 6.9e-13 48.2 0.0 2.9e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ABC_membrane_2 PF06472.10 ETS88090.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AT_hook PF02178.14 ETS88090.1 - 0.65 9.8 17.8 3.6 7.5 2.8 3.4 2 0 0 2 2 2 0 AT hook motif V-ATPase_C PF03223.10 ETS88091.1 - 4.2e-117 391.1 0.1 5.1e-117 390.9 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.15 ETS88092.1 - 9.6e-72 239.7 0.0 1.2e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 ETS88092.1 - 2.2e-07 30.8 0.0 4.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 ETS88092.1 - 2.1e-06 28.5 0.0 3.5e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 ETS88092.1 - 7.6e-05 23.0 0.0 0.00013 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 ETS88092.1 - 0.00015 21.1 0.0 0.00029 20.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 ETS88092.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 ETS88092.1 - 0.029 13.4 0.0 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 ETS88092.1 - 0.082 11.9 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin RNA_pol_L_2 PF13656.1 ETS88092.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain AAA_26 PF13500.1 ETS88092.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 ETS88092.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peroxidase_2 PF01328.12 ETS88094.1 - 4.9e-41 140.4 0.2 6.1e-41 140.1 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Cep57_MT_bd PF06657.8 ETS88095.1 - 0.14 12.0 0.1 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CLAG PF03805.8 ETS88096.1 - 0.15 9.3 0.0 0.19 9.0 0.0 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein 4HBT PF03061.17 ETS88097.1 - 2.4e-12 46.8 0.0 4.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF3945 PF13101.1 ETS88097.1 - 0.008 15.4 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3945) HupF_HypC PF01455.13 ETS88097.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 HupF/HypC family CBF PF03914.12 ETS88099.1 - 1.7e-46 157.6 0.1 1.7e-46 157.6 0.1 2.6 3 0 0 3 3 3 1 CBF/Mak21 family tRNA-synt_2b PF00587.20 ETS88100.1 - 1.9e-33 115.4 0.0 3.3e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 ETS88100.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DnaJ PF00226.26 ETS88101.1 - 3.4e-24 84.3 0.2 8.4e-16 57.4 0.0 3.1 2 1 0 2 2 2 2 DnaJ domain PepSY_TM PF03929.11 ETS88102.1 - 0.28 11.6 10.8 4.4 7.9 1.3 3.2 2 0 0 2 2 2 0 PepSY-associated TM helix Ribosomal_L5_C PF00673.16 ETS88104.1 - 4.3e-22 77.6 0.0 6.2e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 ETS88104.1 - 1.5e-21 75.9 0.1 4.4e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 ETS88105.1 - 5.5e-17 61.0 0.0 8.4e-17 60.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain CPSase_L_D2 PF02786.12 ETS88106.1 - 1.8e-81 272.4 0.6 3e-81 271.7 0.4 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 ETS88106.1 - 2.2e-66 223.0 0.0 4.5e-66 222.0 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 ETS88106.1 - 8.1e-34 116.0 0.0 1.8e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 ETS88106.1 - 3.3e-30 104.2 0.0 8.5e-30 102.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 ETS88106.1 - 3.1e-26 92.5 0.1 7.2e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 HMGL-like ATP-grasp_4 PF13535.1 ETS88106.1 - 6.1e-19 68.4 0.2 1.3e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 ETS88106.1 - 1.3e-18 66.4 3.9 1.4e-18 66.2 1.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 ETS88106.1 - 1.2e-15 57.0 0.0 5.7e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 ETS88106.1 - 5.3e-10 39.0 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 ETS88106.1 - 6.3e-10 38.5 0.8 6.5e-07 28.9 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 ETS88106.1 - 2.6e-07 30.3 0.0 2.7e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 ETS88106.1 - 5.7e-07 29.0 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 ETS88106.1 - 2.2e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 ETS88106.1 - 0.00016 20.9 0.1 0.043 12.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 ETS88106.1 - 0.00026 20.4 0.1 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 ETS88106.1 - 0.0016 18.7 0.1 1.9 8.8 0.0 3.4 2 1 0 3 3 3 1 HlyD family secretion protein MPC PF03650.8 ETS88107.1 - 3.1e-18 65.8 0.1 3.4e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Clathrin PF00637.15 ETS88108.1 - 3.6e-197 645.8 26.9 4.4e-32 110.6 1.1 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 ETS88108.1 - 2.5e-30 104.1 0.2 1.4e-29 101.7 0.1 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 ETS88108.1 - 4.9e-29 98.5 0.3 0.00075 19.6 0.0 7.9 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_12 PF13424.1 ETS88108.1 - 4.4e-06 26.5 3.5 1.8 8.5 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 ETS88108.1 - 0.0012 18.5 12.4 0.82 9.6 0.1 7.4 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF2191 PF09957.4 ETS88108.1 - 0.032 14.0 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_1 PF00515.23 ETS88108.1 - 0.035 13.7 4.9 14 5.4 0.3 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_3 PF13606.1 ETS88108.1 - 0.067 13.4 0.1 5.3 7.5 0.0 3.6 3 0 0 3 3 2 0 Ankyrin repeat TPR_14 PF13428.1 ETS88108.1 - 0.072 13.7 22.5 1.6 9.6 0.0 9.2 11 1 1 12 12 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 ETS88108.1 - 0.29 11.4 15.9 28 5.1 0.1 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 ETS88108.1 - 9.5 6.4 17.1 43 4.3 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1640 PF07798.6 ETS88109.1 - 2e-65 220.1 8.0 2.3e-65 219.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HCaRG PF07258.9 ETS88109.1 - 0.016 14.7 1.8 0.068 12.7 0.0 2.3 1 1 1 2 2 2 0 HCaRG protein Lzipper-MIP1 PF14389.1 ETS88109.1 - 0.017 15.2 3.9 3.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 cwf21 PF08312.7 ETS88109.1 - 0.023 14.5 2.1 0.081 12.7 1.5 2.0 1 1 0 1 1 1 0 cwf21 domain Syntaxin PF00804.20 ETS88109.1 - 0.17 12.0 10.3 0.05 13.7 2.6 2.8 1 1 1 3 3 3 0 Syntaxin Metal_resist PF13801.1 ETS88109.1 - 0.21 11.5 9.3 0.021 14.7 2.6 2.2 1 1 0 1 1 1 0 Heavy-metal resistance Mod_r PF07200.8 ETS88110.1 - 8.6e-09 35.4 8.1 2.8e-08 33.8 5.6 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein MerR PF00376.18 ETS88110.1 - 0.013 15.0 0.1 0.035 13.6 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein F-box PF00646.28 ETS88112.1 - 2.7e-05 23.6 0.1 6.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 ETS88112.1 - 0.00093 18.8 0.8 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like NAD_binding_10 PF13460.1 ETS88113.1 - 3.8e-08 33.5 0.2 2e-07 31.2 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS88113.1 - 0.00037 19.2 0.0 0.00049 18.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 ETS88113.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 ETS88113.1 - 0.073 11.9 0.0 0.34 9.7 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 ETS88113.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus XPA_C PF05181.7 ETS88114.1 - 0.014 14.9 0.7 3.8 7.1 0.1 2.7 3 0 0 3 3 3 0 XPA protein C-terminus YLP PF02757.12 ETS88114.1 - 0.97 9.3 9.2 43 4.3 0.2 4.0 3 0 0 3 3 3 0 YLP motif DUF2729 PF10870.3 ETS88114.1 - 7.4 6.3 12.4 27 4.5 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2729) DUF3328 PF11807.3 ETS88115.1 - 1.3e-47 162.3 3.7 1.5e-47 162.1 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS88116.1 - 5.6e-24 85.0 4.3 8.5e-24 84.4 3.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS88117.1 - 2.4e-30 105.8 0.0 2.9e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS88118.1 - 6.4e-38 130.6 0.2 8.5e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 ETS88119.1 - 3.6e-05 23.5 0.1 4.2e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.6 ETS88120.1 - 2.7e-26 92.3 3.9 3.6e-25 88.7 2.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CDC45 PF02724.9 ETS88120.1 - 0.0072 14.4 12.0 0.012 13.7 8.3 1.3 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 ETS88120.1 - 0.54 9.6 10.6 0.84 9.0 7.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TraH_2 PF06871.6 ETS88120.1 - 1.5 8.2 4.6 0.74 9.2 1.7 1.5 1 1 0 1 1 1 0 TraH_2 RRN3 PF05327.6 ETS88120.1 - 1.7 6.6 9.7 3.2 5.7 6.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 ETS88120.1 - 1.9 7.0 6.4 2.8 6.4 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 ETS88120.1 - 2 6.0 5.2 2.7 5.5 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 ETS88120.1 - 3.2 6.6 8.7 5.3 5.9 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 ETS88120.1 - 3.9 6.5 27.1 10 5.1 18.8 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 ETS88120.1 - 5.9 4.6 33.1 8.2 4.2 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family Nup84_Nup100 PF04121.8 ETS88121.1 - 2.1e-65 220.7 0.0 1.2e-64 218.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.3 ETS88122.1 - 4.4e-20 71.1 0.1 5.5e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 ETS88122.1 - 2e-08 33.4 0.1 2.4e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 ETS88122.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain LIM PF00412.17 ETS88123.1 - 2.2e-25 88.4 19.7 4.1e-08 33.1 0.8 3.3 3 0 0 3 3 3 3 LIM domain MFS_1 PF07690.11 ETS88124.1 - 3e-21 75.5 51.5 7.9e-14 51.1 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NPR3 PF03666.8 ETS88125.1 - 1.2e-128 429.5 0.0 1.7e-128 429.0 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HLH PF00010.21 ETS88126.1 - 5.3e-13 48.4 0.0 3.3e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 ETS88126.1 - 0.055 13.6 0.8 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Patatin phospholipase Got1 PF04178.7 ETS88127.1 - 6.9e-31 106.8 15.8 8.8e-31 106.4 11.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.12 ETS88128.1 - 3e-13 49.3 0.0 5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 La domain Fungal_trans PF04082.13 ETS88129.1 - 2e-21 76.0 0.1 4.9e-21 74.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS88129.1 - 1.3e-09 37.8 9.8 3.8e-09 36.3 6.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ligase_CoA PF00549.14 ETS88130.1 - 3.7e-34 117.5 3.4 1.8e-18 66.6 0.2 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 ETS88130.1 - 1.5e-16 60.6 0.6 6.4e-16 58.6 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 ETS88130.1 - 4.4e-10 39.3 0.1 1.6e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain Lipoprotein_15 PF03640.10 ETS88130.1 - 0.18 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function CHCH PF06747.8 ETS88131.1 - 0.00072 19.4 0.6 0.001 18.8 0.4 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 ETS88131.1 - 0.075 13.0 1.9 0.36 10.9 1.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Granulin PF00396.13 ETS88132.1 - 1.8 8.7 21.7 29 4.8 0.2 4.5 2 1 1 3 3 3 0 Granulin DUF3546 PF12066.3 ETS88133.1 - 3.6e-25 88.1 3.2 3.6e-25 88.1 2.2 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 ETS88133.1 - 1.1e-24 85.7 0.1 2.6e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 ETS88133.1 - 2.8e-11 44.0 1.5 6.1e-11 42.9 1.0 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Rax2 PF12768.2 ETS88134.1 - 3.1e-85 285.8 30.0 6.8e-81 271.5 0.1 5.7 3 2 2 6 6 6 4 Cortical protein marker for cell polarity SNase PF00565.12 ETS88135.1 - 1.2e-24 86.5 0.0 1.7e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue OGG_N PF07934.7 ETS88137.1 - 2.9e-34 117.5 0.1 5.3e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 ETS88137.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 ETS88137.1 - 0.00051 19.6 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Adeno_VII PF03228.9 ETS88137.1 - 0.11 13.0 1.0 0.71 10.4 0.6 2.4 2 1 0 2 2 2 0 Adenoviral core protein VII RRM_1 PF00076.17 ETS88138.1 - 3.5e-26 90.6 0.1 4.4e-12 45.4 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS88138.1 - 5.2e-18 64.7 0.0 1.2e-05 25.1 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS88138.1 - 6.3e-15 54.7 0.1 1.2e-07 31.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 ETS88139.1 - 1.7e-41 142.5 0.0 2.8e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 ETS88139.1 - 1.7e-05 24.1 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 ETS88139.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 ETS88139.1 - 0.076 11.6 0.1 0.3 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) PGA_cap PF09587.5 ETS88140.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap p450 PF00067.17 ETS88141.1 - 4.6e-57 193.5 0.0 6.2e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT_3 PF13622.1 ETS88142.1 - 2e-29 103.1 1.8 2.5e-29 102.7 1.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 ETS88142.1 - 5.5e-10 38.9 0.0 2.5e-08 33.6 0.0 2.4 2 1 1 3 3 3 1 Acyl-CoA thioesterase Fungal_trans PF04082.13 ETS88143.1 - 3.7e-08 32.5 0.4 6.5e-08 31.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 ETS88143.1 - 1.2e-07 31.4 8.8 2.3e-07 30.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMEI PF04043.10 ETS88143.1 - 0.16 11.8 2.7 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Flavoprotein PF02441.14 ETS88144.1 - 1.1e-29 102.7 0.3 1.5e-29 102.2 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein RFX1_trans_act PF04589.8 ETS88144.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 RFX1 transcription activation region UbiD PF01977.11 ETS88145.1 - 9e-135 449.2 0.0 1e-134 449.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ADH_N PF08240.7 ETS88146.1 - 1.4e-12 47.3 0.0 3.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 ETS88146.1 - 9.7e-10 39.4 0.0 2.2e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 ETS88146.1 - 4.7e-07 29.4 0.5 9.3e-07 28.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3176 PF11374.3 ETS88147.1 - 2e-32 111.3 0.8 4.2e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Ank_2 PF12796.2 ETS88148.1 - 8.5e-30 102.9 2.4 7.9e-07 29.3 0.0 8.2 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 ETS88148.1 - 3.3e-20 70.7 22.3 0.00017 21.2 0.6 11.3 12 0 0 12 12 12 5 Ankyrin repeat Ank_3 PF13606.1 ETS88148.1 - 8.7e-18 62.6 14.9 0.093 13.0 0.0 11.3 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.1 ETS88148.1 - 6.3e-16 58.4 9.2 0.0023 18.3 0.0 7.9 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 ETS88148.1 - 6.2e-15 54.8 14.3 0.16 12.3 0.0 8.9 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Clr5 PF14420.1 ETS88148.1 - 2e-06 27.5 0.1 4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain Zn_clus PF00172.13 ETS88150.1 - 1.7e-09 37.4 8.4 2.8e-09 36.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.8 ETS88150.1 - 0.011 15.6 0.8 18 5.3 0.0 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.11 ETS88151.1 - 4.1e-21 75.0 20.0 4.9e-21 74.8 13.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS88151.1 - 8e-10 37.8 6.3 9e-10 37.7 4.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 ETS88151.1 - 1.9e-05 22.9 2.2 3.5e-05 22.0 1.6 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 ETS88152.1 - 8.1e-06 24.7 37.5 8.1e-06 24.7 26.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Myco_arth_vir_N PF09610.5 ETS88152.1 - 0.041 13.8 0.2 0.041 13.8 0.1 2.4 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) BRCT PF00533.21 ETS88152.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Dioxygenase_C PF00775.16 ETS88153.1 - 4e-08 32.7 0.1 6.6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Abhydrolase_6 PF12697.2 ETS88154.1 - 2.6e-34 119.1 0.0 3e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 ETS88154.1 - 8.2e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS88154.1 - 1.1e-06 28.3 0.0 0.0043 16.6 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase PF07224.6 ETS88154.1 - 0.003 16.4 0.0 0.0066 15.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 ETS88154.1 - 0.021 13.7 0.0 0.13 11.1 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 ETS88154.1 - 0.037 13.2 0.0 10 5.3 0.0 2.7 3 0 0 3 3 3 0 Dienelactone hydrolase family UPF0150 PF03681.10 ETS88154.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) PGAP1 PF07819.8 ETS88154.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Phage_RpbA PF10789.4 ETS88154.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Phage RNA polymerase binding, RpbA DUF4122 PF13498.1 ETS88154.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4122) Pec_lyase_C PF00544.14 ETS88155.1 - 8.4e-22 77.6 2.7 1.4e-21 76.8 1.9 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 ETS88155.1 - 0.00054 19.7 18.0 0.15 11.7 0.3 3.0 1 1 0 2 2 2 2 Right handed beta helix region Acyl-CoA_dh_1 PF00441.19 ETS88156.1 - 5.3e-26 91.5 0.1 7.8e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 ETS88156.1 - 7.1e-12 45.9 0.0 2.3e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 ETS88156.1 - 2.9e-08 33.0 0.2 6.4e-08 31.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.11 ETS88157.1 - 9.8e-39 133.0 27.0 9.8e-39 133.0 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS88157.1 - 3e-13 49.1 8.3 3e-13 49.1 5.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 ETS88158.1 - 1.5e-07 31.2 8.1 3.4e-07 30.0 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 ETS88158.1 - 1.6e-07 30.4 0.4 4.7e-07 28.9 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPAP3_C PF13877.1 ETS88158.1 - 0.021 14.8 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Cyt-b5 PF00173.23 ETS88160.1 - 5.4e-12 45.3 0.0 8.3e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_15 PF01793.11 ETS88161.1 - 5.1e-117 390.5 5.7 6.4e-117 390.1 4.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.9 ETS88162.1 - 2.1e-103 346.0 8.4 2.4e-103 345.8 5.8 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 ETS88163.1 - 1.6e-42 145.4 3.6 2.2e-42 145.0 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 ETS88163.1 - 2.6e-12 46.3 8.3 4.9e-12 45.4 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 ETS88163.1 - 1e-11 44.6 8.0 1.9e-11 43.7 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS88163.1 - 3.1e-10 39.5 6.8 6.3e-10 38.5 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS88163.1 - 6.1e-09 35.4 9.1 9.7e-09 34.7 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ETS88163.1 - 2.5e-08 33.4 5.7 4.3e-08 32.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 ETS88163.1 - 2.3e-06 27.3 8.1 4.1e-06 26.5 5.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 ETS88163.1 - 8e-05 22.6 7.4 0.00026 21.0 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 ETS88163.1 - 0.00075 19.2 4.6 0.0015 18.2 3.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 ETS88163.1 - 0.0012 18.5 6.8 0.0027 17.4 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 ETS88163.1 - 0.0028 17.1 1.5 0.0051 16.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 ETS88163.1 - 0.3 10.9 6.4 0.82 9.5 4.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 ETS88163.1 - 0.33 10.5 11.3 0.6 9.7 7.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 ETS88163.1 - 2.1 8.2 8.0 7.2 6.5 5.5 1.8 1 1 0 1 1 1 0 IBR domain Dioxygenase_C PF00775.16 ETS88164.1 - 1.2e-09 37.7 0.0 1.5e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase PALP PF00291.20 ETS88165.1 - 2e-53 181.6 0.1 3.4e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 ETS88165.1 - 3.2e-27 95.2 0.0 5.8e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 ETS88165.1 - 2.9e-19 68.8 0.0 7.7e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_hydro_18 PF00704.23 ETS88166.1 - 8.4e-67 226.0 2.3 1.9e-66 224.8 1.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 ETS88166.1 - 6e-10 38.9 12.5 6e-10 38.9 8.7 6.1 6 0 0 6 6 6 1 Chitin recognition protein DNase_NucA_NucB PF14040.1 ETS88166.1 - 0.0045 17.1 0.2 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 ETS88167.1 - 2e-06 27.5 0.6 0.016 15.0 0.0 3.4 3 0 0 3 3 3 2 LysM domain LysM PF01476.15 ETS88169.1 - 4.6e-21 74.4 0.0 6.8e-05 22.6 0.0 4.3 4 0 0 4 4 4 4 LysM domain W_rich_C PF07483.6 ETS88169.1 - 0.059 13.0 0.4 0.84 9.3 0.0 2.8 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain SapB_2 PF03489.12 ETS88169.1 - 0.12 12.4 0.2 3.7 7.6 0.1 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 2 Mucin PF01456.12 ETS88169.1 - 0.94 9.2 49.6 0.044 13.5 5.4 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein Phosphoprotein PF00922.12 ETS88169.1 - 6 5.9 6.3 3.2 6.9 0.5 2.3 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Rubella_E2 PF05749.6 ETS88169.1 - 10 5.3 31.4 0.29 10.3 3.4 3.2 1 1 1 3 3 3 0 Rubella membrane glycoprotein E2 Fungal_trans PF04082.13 ETS88171.1 - 5.4e-22 77.9 0.5 8.1e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 ETS88172.1 - 8.2e-57 192.7 0.0 1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 ETS88172.1 - 8.3e-07 29.3 0.2 2.1e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 ETS88172.1 - 0.011 15.1 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 ETS88173.1 - 2.6e-38 131.6 25.3 6.5e-37 127.0 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_1 PF01979.15 ETS88174.1 - 1.9e-38 132.9 0.7 2.3e-38 132.6 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS88174.1 - 7.6e-16 58.9 5.8 1.4e-15 58.1 4.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 ETS88174.1 - 3.8e-10 39.4 0.9 9.3e-10 38.1 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS88174.1 - 1.7e-09 37.4 7.5 2.5e-08 33.5 1.3 2.3 2 0 0 2 2 2 2 Amidohydrolase family NACHT PF05729.7 ETS88175.1 - 1.1e-06 28.4 0.0 3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 ETS88175.1 - 0.00056 19.9 0.0 0.0023 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 ETS88175.1 - 0.0015 18.3 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 ETS88175.1 - 0.06 13.4 0.0 0.77 9.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 ETS88175.1 - 0.076 12.9 0.0 0.41 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 ETS88175.1 - 0.08 12.3 0.0 0.37 10.1 0.0 2.1 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 ETS88175.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.2 ETS88175.1 - 0.16 12.3 0.0 0.51 10.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NDUF_B8 PF05821.6 ETS88176.1 - 2.6e-05 23.9 0.1 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 ETS88177.1 - 9.9e-74 247.8 0.5 1.8e-73 246.9 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 ETS88177.1 - 5.4e-15 55.0 0.1 2e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 ETS88177.1 - 3.9e-08 33.3 0.7 7.9e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.8 ETS88177.1 - 0.0035 17.1 7.4 0.0035 17.1 5.1 2.7 1 1 2 3 3 3 1 HSA SCAN PF02023.12 ETS88177.1 - 0.02 14.3 2.5 0.1 12.0 0.7 2.6 2 0 0 2 2 2 0 SCAN domain DUF367 PF04034.8 ETS88177.1 - 0.058 13.0 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF367) zf-HIT PF04438.11 ETS88178.1 - 1.2e-09 37.5 4.7 1.8e-09 37.0 3.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Nicastrin PF05450.10 ETS88179.1 - 0.011 14.9 1.1 0.62 9.2 0.1 2.2 2 0 0 2 2 2 0 Nicastrin KAR9 PF08580.5 ETS88179.1 - 9.5 4.3 9.8 11 4.1 6.8 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 VRR_NUC PF08774.6 ETS88180.1 - 3.3e-17 62.3 0.0 7.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain MFS_1 PF07690.11 ETS88181.1 - 5.8e-37 127.2 47.9 3.9e-28 98.1 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Dpy-30 PF05186.8 ETS88183.1 - 3.4e-15 55.2 0.0 5.1e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif TFIIA PF03153.8 ETS88183.1 - 0.0062 16.4 7.4 0.0064 16.4 5.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4150 PF13665.1 ETS88183.1 - 0.074 12.9 5.8 0.081 12.8 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4150) Ribosomal_S13_N PF08069.7 ETS88184.1 - 1.2e-29 101.9 0.1 2.4e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 ETS88184.1 - 6.8e-23 80.2 0.0 1.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 ETS88184.1 - 0.016 14.9 0.1 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain WD40 PF00400.27 ETS88185.1 - 3.2e-67 220.1 23.6 4.1e-09 35.9 0.1 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 ETS88185.1 - 2.6e-21 75.5 0.8 4.8e-21 74.7 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 ETS88185.1 - 3.4e-05 22.1 2.6 0.091 10.8 0.0 4.9 5 1 0 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 ETS88185.1 - 9.5e-05 22.1 4.4 5.7 6.7 0.0 6.8 4 3 3 7 7 7 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 ETS88185.1 - 0.00053 19.7 0.2 0.41 10.3 0.0 3.7 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 ETS88185.1 - 0.00054 18.8 3.5 2 7.0 0.1 4.5 1 1 1 3 3 3 1 Nup133 N terminal like UTP15_C PF09384.5 ETS88185.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal P34-Arc PF04045.9 ETS88186.1 - 1.5e-10 40.7 0.0 2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc P34-Arc PF04045.9 ETS88187.1 - 5.6e-78 261.5 1.7 6.5e-78 261.3 1.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 ETS88187.1 - 0.054 12.8 0.4 0.097 12.0 0.3 1.3 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.16 ETS88187.1 - 0.12 12.5 0.1 0.37 10.9 0.0 1.7 1 1 1 2 2 2 0 Radical SAM superfamily Hemerythrin PF01814.18 ETS88187.1 - 0.14 12.3 2.2 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain SF3b1 PF08920.5 ETS88188.1 - 8.1e-31 107.0 1.0 2.9e-30 105.2 0.0 2.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 ETS88188.1 - 3.2e-15 56.1 3.0 0.011 16.0 0.0 7.5 6 3 3 9 9 9 6 HEAT repeats HEAT_EZ PF13513.1 ETS88188.1 - 5.6e-11 42.5 0.3 0.33 11.5 0.0 7.5 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.17 ETS88188.1 - 3.2e-10 39.2 8.5 0.96 9.7 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 ETS88188.1 - 3.6e-05 24.0 0.2 0.9 9.9 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 ETS88188.1 - 0.00016 20.1 0.1 0.085 11.1 0.0 3.1 2 2 0 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 ETS88188.1 - 0.0017 16.8 0.0 0.003 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 ETS88188.1 - 0.018 14.4 0.3 0.91 8.8 0.0 3.4 4 0 0 4 4 4 0 CLASP N terminal NUC173 PF08161.7 ETS88188.1 - 0.019 14.3 0.4 9 5.5 0.0 3.7 4 0 0 4 4 4 0 NUC173 domain Dopey_N PF04118.9 ETS88188.1 - 0.18 10.5 0.0 37 2.9 0.0 3.5 4 0 0 4 4 4 0 Dopey, N-terminal DUF2890 PF11081.3 ETS88188.1 - 0.37 10.8 10.4 1.1 9.3 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-C2H2 PF00096.21 ETS88189.1 - 3.2e-10 39.7 12.5 2.2e-05 24.5 3.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 ETS88189.1 - 5.8e-09 35.8 17.1 2e-05 24.6 0.3 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 ETS88189.1 - 1.5e-06 28.1 9.5 0.00022 21.3 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 ETS88189.1 - 7.1e-06 26.0 1.5 2.2e-05 24.4 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 ETS88189.1 - 7.7e-05 22.7 5.1 0.00013 21.9 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 ETS88189.1 - 0.00081 19.2 6.6 0.0044 16.8 1.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 ETS88189.1 - 0.044 13.8 1.0 0.044 13.8 0.7 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 ETS88189.1 - 2.7 7.8 5.9 21 4.9 4.1 2.2 1 1 0 1 1 1 0 BED zinc finger RAP1 PF07218.6 ETS88189.1 - 3.1 5.7 7.2 4 5.4 5.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-H2C2_5 PF13909.1 ETS88189.1 - 5.6 7.3 7.8 5.2 7.5 0.9 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Methyltransf_26 PF13659.1 ETS88191.1 - 6.2e-15 55.2 1.5 8.7e-15 54.7 1.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF1269 PF06897.7 ETS88191.1 - 0.023 14.6 0.0 0.071 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) MTS PF05175.9 ETS88191.1 - 0.032 13.6 0.0 0.19 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 ETS88192.1 - 0.0045 16.5 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF2763 PF10961.3 ETS88192.1 - 0.89 9.9 6.7 1.2 9.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) FXR1P_C PF12235.3 ETS88192.1 - 3.3 7.7 10.1 4.3 7.4 7.0 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Pkr1 PF08636.5 ETS88193.1 - 1.3e-34 118.1 4.4 1.6e-34 117.7 3.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 ETS88193.1 - 0.002 16.5 0.0 0.0022 16.4 0.0 1.0 1 0 0 1 1 1 1 FHIPEP family DUF3429 PF11911.3 ETS88193.1 - 0.0034 17.3 0.6 0.0044 16.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) OAD_gamma PF04277.8 ETS88193.1 - 0.0076 16.6 0.6 0.026 14.8 0.4 2.0 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain VIT1 PF01988.14 ETS88193.1 - 0.078 12.4 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 VIT family Phage_Gp23 PF10669.4 ETS88193.1 - 0.2 11.7 0.9 2.5 8.2 0.6 2.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-C2H2 PF00096.21 ETS88194.1 - 0.0013 18.9 3.8 0.22 11.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ETS88194.1 - 0.0014 18.8 4.5 0.28 11.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ETS88194.1 - 0.021 15.1 0.8 0.061 13.6 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 ETS88194.1 - 0.26 11.2 2.8 12 6.0 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Cullin PF00888.17 ETS88195.1 - 1.5e-49 169.0 0.1 5e-49 167.3 0.0 1.8 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 ETS88195.1 - 9.5e-21 73.8 0.2 2.6e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-RING_2 PF13639.1 ETS88196.1 - 4.5e-12 45.5 3.2 7.9e-12 44.8 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 ETS88196.1 - 1.4e-11 44.3 0.4 2.3e-11 43.6 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 ETS88196.1 - 1.4e-07 31.2 0.2 2.6e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 ETS88196.1 - 4.4e-06 26.3 1.9 7.6e-06 25.5 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 ETS88196.1 - 8e-06 25.7 2.8 2.2e-05 24.3 1.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 ETS88196.1 - 9.2e-05 22.0 3.1 0.00016 21.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS88196.1 - 0.00031 20.3 1.2 0.00065 19.3 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 ETS88196.1 - 0.00039 20.0 1.1 0.00095 18.8 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 ETS88196.1 - 0.016 14.7 0.4 0.039 13.4 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 ETS88196.1 - 0.017 14.9 0.1 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 ETS88196.1 - 0.069 13.1 6.7 0.59 10.1 3.3 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 ETS88196.1 - 0.47 10.3 3.1 0.22 11.3 0.4 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Metallophos_2 PF12850.2 ETS88197.1 - 1.1e-10 41.6 0.1 2.8e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 ETS88197.1 - 4.5e-08 32.7 1.7 0.0054 16.1 0.2 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase ABC2_membrane_3 PF12698.2 ETS88197.1 - 0.024 13.6 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MAD PF05557.8 ETS88198.1 - 0.0034 15.5 93.8 0.04 12.0 5.1 4.6 1 1 4 5 5 5 3 Mitotic checkpoint protein ADIP PF11559.3 ETS88198.1 - 0.0092 15.8 1.4 0.0092 15.8 1.0 7.9 2 1 6 9 9 9 2 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 ETS88198.1 - 0.075 11.2 83.1 0.047 11.9 38.6 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 ETS88198.1 - 0.097 12.5 105.3 0.1 12.4 9.8 7.6 1 1 6 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFP_35_N PF07334.8 ETS88198.1 - 0.5 10.3 11.6 1.2 9.1 0.3 4.6 3 1 1 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GAS PF13851.1 ETS88198.1 - 0.82 8.8 90.8 0.079 12.1 10.6 6.1 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 ETS88198.1 - 3.6 7.1 102.0 0.86 9.1 10.3 6.2 1 1 6 7 7 7 0 IncA protein Reo_sigmaC PF04582.7 ETS88198.1 - 4.4 6.3 37.8 3.1 6.8 5.4 5.2 1 1 4 6 6 6 0 Reovirus sigma C capsid protein Methyltransf_11 PF08241.7 ETS88199.1 - 7.1e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS88199.1 - 1.3e-17 63.7 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 ETS88199.1 - 1.2e-16 60.5 0.0 1.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 ETS88199.1 - 4.4e-14 52.6 0.0 7.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS88199.1 - 8.7e-12 45.3 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 ETS88199.1 - 8.1e-10 38.6 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS88199.1 - 1.1e-08 35.6 0.0 1.7e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 ETS88199.1 - 3.2e-06 25.7 0.0 6.6e-06 24.7 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 ETS88199.1 - 6.5e-06 26.1 0.1 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 ETS88199.1 - 0.00026 20.5 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 ETS88199.1 - 0.00028 19.9 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 ETS88199.1 - 0.00057 19.5 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase MetW PF07021.7 ETS88199.1 - 0.0019 17.6 0.0 0.0054 16.1 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 ETS88199.1 - 0.0043 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 ETS88199.1 - 0.01 15.1 0.0 0.83 8.9 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 ETS88199.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CFEM PF05730.6 ETS88200.1 - 2.9e-12 46.2 13.0 5.1e-12 45.4 9.0 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 ETS88200.1 - 0.047 13.7 1.2 0.1 12.5 0.8 1.6 1 0 0 1 1 1 0 Gamma-thionin family MFS_1 PF07690.11 ETS88202.1 - 5.3e-39 133.9 49.9 5.3e-39 133.9 34.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily OMP_b-brl PF13505.1 ETS88204.1 - 0.038 13.9 1.0 0.06 13.2 0.7 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain HET PF06985.6 ETS88205.1 - 5.4e-21 75.2 8.3 1.5e-18 67.2 1.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mito_fiss_reg PF05308.6 ETS88206.1 - 0.004 16.5 1.4 0.0052 16.1 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 ETS88206.1 - 0.036 13.3 5.0 0.052 12.8 3.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Staph_haemo PF05480.6 ETS88207.1 - 0.087 12.5 6.2 0.29 10.8 0.6 3.5 2 1 1 3 3 3 0 Staphylococcus haemolytic protein Mastoparan_2 PF08251.6 ETS88207.1 - 0.29 11.2 1.2 38 4.7 0.1 3.1 2 0 0 2 2 2 0 Mastoparan peptide Toxin_40 PF15520.1 ETS88207.1 - 1.3 8.4 9.8 0.038 13.4 0.8 2.3 2 0 0 2 2 2 0 Putative toxin 40 HET PF06985.6 ETS88208.1 - 7.1e-19 68.3 2.4 2.9e-18 66.3 1.7 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.18 ETS88209.1 - 9.8e-09 35.1 0.0 3.7e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 ETS88209.1 - 1.4e-08 34.0 0.0 1.4e-08 34.0 0.0 2.0 1 1 0 2 2 2 1 AIG1 family DUF258 PF03193.11 ETS88209.1 - 5.2e-05 22.4 0.1 0.00019 20.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 ETS88209.1 - 0.00031 19.8 0.8 0.0008 18.5 0.0 2.0 2 0 0 2 2 2 1 Septin Miro PF08477.8 ETS88209.1 - 0.0012 19.3 1.2 0.0045 17.4 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 ETS88209.1 - 0.0016 18.2 13.2 0.24 11.2 0.0 3.6 2 2 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 ETS88209.1 - 0.0083 16.4 7.8 0.28 11.4 5.4 2.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 ETS88209.1 - 0.022 14.3 0.0 0.06 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 ETS88209.1 - 0.048 12.9 0.2 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 ETS88209.1 - 0.13 12.1 1.3 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF342 PF03961.8 ETS88209.1 - 0.32 9.3 9.6 0.48 8.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_17 PF13207.1 ETS88209.1 - 0.34 11.7 2.5 0.44 11.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 ETS88209.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.2 2 1 0 2 2 1 0 AAA domain Caldesmon PF02029.10 ETS88209.1 - 0.53 8.6 17.6 0.72 8.2 12.2 1.1 1 0 0 1 1 1 0 Caldesmon DUF87 PF01935.12 ETS88209.1 - 0.57 9.9 0.1 0.57 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 ETS88209.1 - 0.77 8.4 5.1 1.1 7.9 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 ETS88209.1 - 0.81 9.9 0.0 0.81 9.9 0.0 2.4 2 1 0 2 2 1 0 AAA domain GTP_EFTU PF00009.22 ETS88209.1 - 1.3 8.3 5.1 6.9 6.0 0.2 3.0 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF755 PF05501.6 ETS88209.1 - 2.4 8.2 6.6 4.4 7.3 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AAA_18 PF13238.1 ETS88209.1 - 5 7.4 7.9 4.1 7.7 0.3 2.7 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 ETS88209.1 - 7.2 6.1 17.0 12 5.4 11.8 1.4 1 0 0 1 1 1 0 IncA protein CENP-H PF05837.7 ETS88209.1 - 9.7 6.4 18.1 12 6.0 1.9 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HET PF06985.6 ETS88210.1 - 2.4e-20 73.0 0.0 4.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Patatin PF01734.17 ETS88211.1 - 2.5e-14 53.6 0.0 6.7e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-B_box PF00643.19 ETS88211.1 - 7.3e-06 25.7 4.7 7.3e-06 25.7 3.3 2.7 3 0 0 3 3 2 1 B-box zinc finger ABC_tran PF00005.22 ETS88211.1 - 0.0031 17.7 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter zf-RING_UBOX PF13445.1 ETS88211.1 - 0.011 15.4 0.3 0.011 15.4 0.2 2.1 2 0 0 2 2 1 0 RING-type zinc-finger DUF258 PF03193.11 ETS88211.1 - 0.021 14.0 0.0 0.058 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 ETS88211.1 - 0.04 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 ETS88211.1 - 0.046 13.6 0.1 0.34 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 ETS88211.1 - 0.058 12.9 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-C3HC4_2 PF13923.1 ETS88211.1 - 0.1 12.6 21.6 0.039 13.9 4.5 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 ETS88211.1 - 0.12 12.0 21.1 0.075 12.7 4.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 ETS88211.1 - 0.13 12.1 0.0 0.67 9.9 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.12 ETS88211.1 - 0.14 11.9 0.2 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 ETS88211.1 - 0.21 11.2 0.1 0.43 10.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RING_5 PF14634.1 ETS88211.1 - 1 9.1 22.2 0.4 10.4 4.7 2.6 2 0 0 2 2 2 0 zinc-RING finger domain PA14_2 PF10528.4 ETS88213.1 - 4.2e-21 75.0 0.4 4.2e-21 75.0 0.3 2.7 4 0 0 4 4 4 1 GLEYA domain PA14 PF07691.7 ETS88213.1 - 0.00049 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 PA14 domain GMC_oxred_N PF00732.14 ETS88214.1 - 8.3e-62 209.0 0.0 1.1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 ETS88214.1 - 1.5e-39 135.5 0.2 3.4e-39 134.3 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 ETS88214.1 - 7.4e-06 25.1 0.0 5.8e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 ETS88214.1 - 1.4e-05 24.1 0.1 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 ETS88214.1 - 4e-05 23.5 0.1 0.00011 22.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 ETS88214.1 - 0.00026 20.0 0.1 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 ETS88214.1 - 0.00067 19.5 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 ETS88214.1 - 0.0023 17.0 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 ETS88214.1 - 0.0091 16.0 0.1 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 ETS88214.1 - 0.051 12.0 0.0 0.084 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 ETS88214.1 - 0.089 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4038 PF13204.1 ETS88215.1 - 1.5e-55 188.5 2.2 4.2e-33 114.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.2 ETS88215.1 - 6.1e-13 48.3 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase MFS_1 PF07690.11 ETS88216.1 - 1.1e-37 129.5 30.1 1.1e-37 129.5 20.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.25 ETS88217.1 - 3e-09 36.5 0.1 2.2e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 C2 domain Methyltransf_23 PF13489.1 ETS88219.1 - 4.1e-18 65.6 0.0 7.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 ETS88219.1 - 1.6e-11 44.0 0.0 4.1e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 ETS88219.1 - 8.9e-09 35.7 0.0 2.2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 ETS88219.1 - 6.4e-08 32.9 0.0 4.6e-07 30.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 ETS88219.1 - 2.1e-07 31.5 0.0 9.9e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 ETS88219.1 - 3.3e-05 24.1 0.0 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 ETS88219.1 - 0.00069 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 ETS88219.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 ETS88219.1 - 0.0047 15.9 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 ETS88219.1 - 0.026 13.7 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 ETS88219.1 - 0.05 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short_C2 PF13561.1 ETS88220.1 - 7.6e-26 91.3 0.1 8.9e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 ETS88220.1 - 3.5e-25 88.8 0.1 1e-24 87.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 ETS88220.1 - 1.5e-06 28.0 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 ETS88220.1 - 0.00096 18.6 0.1 0.0045 16.4 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 ETS88220.1 - 0.0059 16.6 0.0 0.0099 15.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 ETS88220.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1445 PF07286.7 ETS88220.1 - 0.042 13.4 0.1 9.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) Polysacc_synt_2 PF02719.10 ETS88220.1 - 0.047 12.5 0.0 0.097 11.5 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_18 PF12847.2 ETS88220.1 - 0.089 13.3 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Evr1_Alr PF04777.8 ETS88221.1 - 6.3e-26 90.1 0.1 9.3e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family AA_permease PF00324.16 ETS88221.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Proteasome PF00227.21 ETS88222.1 - 6.1e-50 169.1 0.2 7.1e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 ETS88223.1 - 1.3e-39 135.9 1.6 4.4e-23 82.3 0.1 2.6 2 0 0 2 2 2 2 Cyclin DUF605 PF04652.11 ETS88223.1 - 7.2 5.9 38.2 8 5.7 0.5 2.2 2 0 0 2 2 2 0 Vta1 like MFS_1 PF07690.11 ETS88226.1 - 5.1e-28 97.7 66.4 2.9e-27 95.3 43.9 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 ETS88226.1 - 2.8e-10 39.3 18.2 2.8e-10 39.3 12.6 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter YrhK PF14145.1 ETS88226.1 - 0.02 14.5 2.1 0.02 14.5 1.5 3.4 4 0 0 4 4 4 0 YrhK-like protein Beta-lactamase PF00144.19 ETS88227.1 - 1.1e-33 116.6 0.8 1.9e-33 115.8 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 ETS88227.1 - 4.1e-10 39.3 0.0 9.5e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Delta_lysin PF05372.6 ETS88227.1 - 0.04 13.2 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family p450 PF00067.17 ETS88230.1 - 2.6e-63 214.1 0.0 3.2e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 ETS88231.1 - 6.6e-13 48.9 0.0 1.3e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 ETS88231.1 - 0.0025 17.2 0.0 0.087 12.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 ETS88231.1 - 0.0046 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.17 ETS88232.1 - 1.2e-07 31.2 0.0 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 ETS88232.1 - 2.8e-06 27.2 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS88232.1 - 0.062 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1_C PF07462.6 ETS88232.1 - 6.9 4.9 5.1 9.6 4.4 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Thioredoxin PF00085.15 ETS88234.1 - 3.2e-65 216.3 6.2 1.9e-32 111.0 0.1 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 ETS88234.1 - 3.9e-56 189.7 5.0 3.7e-41 140.9 0.6 3.4 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 ETS88234.1 - 1.3e-13 50.7 0.2 7.2e-06 25.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 ETS88234.1 - 1.4e-13 50.7 0.8 0.00013 22.0 0.0 5.0 4 2 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 ETS88234.1 - 1.6e-12 47.6 6.2 1.7e-05 24.9 0.1 4.6 2 2 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.12 ETS88234.1 - 4.9e-10 38.7 0.8 4.9e-10 38.7 0.6 1.6 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 ETS88234.1 - 4.6e-09 36.0 1.8 0.0021 17.7 0.1 3.6 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 ETS88234.1 - 3.4e-08 33.1 3.4 0.0015 18.0 0.0 3.4 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.8 ETS88234.1 - 0.00042 20.2 0.9 0.93 9.4 0.0 3.8 3 2 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 ETS88234.1 - 0.0013 18.8 2.5 4.1 7.3 0.1 4.4 3 2 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 ETS88234.1 - 0.0021 17.8 1.4 0.018 14.8 0.1 2.9 3 0 0 3 3 3 1 Thioredoxin domain DSBA PF01323.15 ETS88234.1 - 0.0052 16.3 0.2 14 5.1 0.0 4.0 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Leuk-A4-hydro_C PF09127.6 ETS88234.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Amidohydro_1 PF01979.15 ETS88235.1 - 2.6e-24 86.5 0.3 3.3e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 ETS88235.1 - 5.5e-10 39.7 4.8 3e-08 34.0 3.3 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 ETS88235.1 - 1.1e-07 31.4 0.6 1.2e-06 28.0 0.2 2.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 ETS88235.1 - 0.00051 19.8 0.3 0.053 13.3 0.0 2.8 2 0 0 2 2 2 1 Amidohydrolase Mon1 PF03164.9 ETS88237.1 - 4.1e-115 384.6 0.0 5.3e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 ETS88238.1 - 3.1e-120 400.6 0.1 2.6e-119 397.5 0.0 2.4 2 0 0 2 2 2 1 Dopey, N-terminal S1-P1_nuclease PF02265.11 ETS88239.1 - 0.048 13.2 2.0 0.088 12.4 1.2 1.4 1 1 0 1 1 1 0 S1/P1 Nuclease Methyltransf_15 PF09445.5 ETS88240.1 - 1.5e-38 131.9 0.0 2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 ETS88240.1 - 3.5e-07 30.0 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 ETS88240.1 - 6.8e-07 29.8 0.0 9.9e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 ETS88240.1 - 2.3e-05 24.4 0.0 3.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 ETS88240.1 - 0.0004 19.8 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 ETS88240.1 - 0.00053 19.5 0.0 0.00091 18.8 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 ETS88240.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 ETS88240.1 - 0.0016 17.4 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 ETS88240.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 ETS88240.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.9 ETS88241.1 - 1.2e-43 148.3 0.0 6.7e-43 145.9 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain DAD PF02109.11 ETS88242.1 - 1.6e-48 163.4 1.0 2.1e-48 163.0 0.7 1.1 1 0 0 1 1 1 1 DAD family TrbL PF04610.9 ETS88242.1 - 0.0036 17.0 0.9 0.0058 16.3 0.6 1.5 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Acetyltransf_4 PF13420.1 ETS88242.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RDD PF06271.7 ETS88242.1 - 0.023 14.5 0.7 0.039 13.8 0.5 1.5 1 1 0 1 1 1 0 RDD family PhageMin_Tail PF10145.4 ETS88242.1 - 0.45 10.1 4.7 0.65 9.6 3.2 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein Tmemb_14 PF03647.8 ETS88243.1 - 8.4e-21 74.1 7.3 9.5e-21 74.0 5.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 ETS88243.1 - 0.0013 18.9 1.0 0.0025 18.0 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Cmc1 PF08583.5 ETS88244.1 - 2.3e-14 52.9 3.7 2.3e-14 52.9 2.6 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NYD-SP28 PF14772.1 ETS88244.1 - 0.091 12.8 3.6 4.8 7.3 1.3 2.1 2 0 0 2 2 2 0 Sperm tail Ribosomal_L30_N PF08079.7 ETS88244.1 - 0.48 10.4 6.0 0.67 10.0 4.1 1.1 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Prefoldin_2 PF01920.15 ETS88245.1 - 2.1e-26 91.7 6.9 2.4e-26 91.5 4.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 ETS88245.1 - 0.0048 17.2 1.1 0.49 10.8 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Prefoldin PF02996.12 ETS88245.1 - 0.011 15.4 5.7 1.5 8.5 3.9 2.2 1 1 0 1 1 1 0 Prefoldin subunit Mnd1 PF03962.10 ETS88245.1 - 0.012 15.2 3.5 0.02 14.5 2.4 1.4 1 1 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 ETS88245.1 - 0.013 15.3 2.4 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2205 PF10224.4 ETS88245.1 - 0.017 14.6 6.3 0.037 13.5 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Tho2 PF11262.3 ETS88245.1 - 0.026 13.5 1.5 0.73 8.8 0.0 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TMP_2 PF06791.8 ETS88245.1 - 0.028 14.0 0.1 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein ALIX_LYPXL_bnd PF13949.1 ETS88245.1 - 0.035 13.0 2.2 0.079 11.9 1.5 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DASH_Dad3 PF08656.5 ETS88245.1 - 0.061 13.0 3.7 0.075 12.7 0.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 GAS PF13851.1 ETS88245.1 - 0.066 12.3 7.7 0.14 11.2 5.3 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 ETS88245.1 - 0.1 12.5 4.4 0.31 10.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Peptidase_M75 PF09375.5 ETS88245.1 - 0.15 11.3 1.4 8.1 5.6 0.1 2.0 2 0 0 2 2 2 0 Imelysin V_ATPase_I PF01496.14 ETS88245.1 - 0.15 9.8 0.8 0.19 9.5 0.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 ETS88245.1 - 0.21 11.3 8.1 0.87 9.3 0.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 ETS88245.1 - 0.32 11.0 9.5 1.2 9.2 1.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Cytochrom_B562 PF07361.6 ETS88245.1 - 0.34 11.3 5.8 0.86 10.0 0.8 2.1 2 0 0 2 2 2 0 Cytochrome b562 IncA PF04156.9 ETS88245.1 - 0.41 10.2 6.2 1.1 8.8 4.3 1.6 1 1 0 1 1 1 0 IncA protein Syntaxin PF00804.20 ETS88245.1 - 0.95 9.6 4.2 8 6.6 2.8 2.0 1 1 0 1 1 1 0 Syntaxin TMF_DNA_bd PF12329.3 ETS88245.1 - 1.1 9.0 9.2 0.21 11.3 1.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 ETS88245.1 - 3.3 8.0 5.9 14 6.0 1.3 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor PspA_IM30 PF04012.7 ETS88245.1 - 4 6.7 8.8 1.6 8.0 1.1 2.0 2 0 0 2 2 2 0 PspA/IM30 family CBFD_NFYB_HMF PF00808.18 ETS88246.1 - 1.3e-25 89.2 1.1 2.3e-25 88.4 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 ETS88246.1 - 6e-07 29.4 0.1 1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 ETS88246.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 ETS88246.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 ETS88246.1 - 0.1 12.8 0.1 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RRN3 PF05327.6 ETS88247.1 - 3.4e-168 560.2 0.1 3.4e-168 560.2 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF2205 PF10224.4 ETS88248.1 - 0.00017 21.1 0.6 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 ETS88248.1 - 0.19 11.6 16.5 4.2 7.4 10.9 2.3 1 1 0 1 1 1 0 bZIP transcription factor Atg14 PF10186.4 ETS88248.1 - 0.49 9.2 7.1 0.78 8.6 4.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 ETS88248.1 - 2.2 7.7 7.8 3.3 7.1 5.4 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_13 PF13166.1 ETS88248.1 - 6 5.1 7.8 8.3 4.7 5.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3500 PF12006.3 ETS88249.1 - 5.6e-101 337.5 0.0 6.9e-101 337.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF2914 PF11141.3 ETS88249.1 - 0.035 13.6 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) IU_nuc_hydro PF01156.14 ETS88250.1 - 8.8e-36 123.6 0.1 1.2e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase NACHT PF05729.7 ETS88251.1 - 4.2e-08 33.0 1.1 1.7e-06 27.7 0.2 3.0 2 1 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 ETS88251.1 - 0.00014 21.4 0.3 0.0061 16.0 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 ETS88251.1 - 0.00038 20.5 3.8 0.01 15.9 0.0 3.4 3 3 0 3 3 3 1 AAA domain ABC_tran PF00005.22 ETS88251.1 - 0.001 19.4 0.0 0.0051 17.1 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 ETS88251.1 - 0.0013 19.0 4.4 0.06 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 ETS88251.1 - 0.0015 17.4 0.0 0.0054 15.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 ETS88251.1 - 0.0019 18.2 0.2 0.015 15.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 ETS88251.1 - 0.017 15.9 1.6 0.051 14.4 0.2 2.6 2 2 0 2 2 1 0 AAA domain Miro PF08477.8 ETS88251.1 - 0.019 15.4 0.0 0.062 13.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 ETS88251.1 - 0.031 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 ETS88251.1 - 0.035 13.8 0.4 0.25 11.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 ETS88251.1 - 0.047 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Imm8 PF15560.1 ETS88251.1 - 0.05 13.2 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 8 AAA_33 PF13671.1 ETS88251.1 - 0.074 12.9 0.0 0.24 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 ETS88251.1 - 0.078 13.2 0.7 0.49 10.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 ETS88251.1 - 0.079 12.7 2.4 0.19 11.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 ETS88251.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 ETS88251.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 ETS88251.1 - 0.11 12.6 0.7 4.5 7.4 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CFEM PF05730.6 ETS88252.1 - 1.3e-12 47.3 11.2 2.2e-12 46.6 7.8 1.4 1 0 0 1 1 1 1 CFEM domain AMP-binding PF00501.23 ETS88253.1 - 3.9e-79 265.9 0.0 7.9e-79 264.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 ETS88253.1 - 2.9e-62 209.8 0.1 3.3e-61 206.3 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 ETS88253.1 - 1.3e-32 113.0 7.2 4.7e-31 107.9 1.8 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 ETS88253.1 - 1.8e-23 83.2 0.3 2.7e-12 46.6 0.0 3.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 ETS88253.1 - 6.4e-21 75.2 0.7 1.4e-20 74.0 0.5 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 ETS88253.1 - 2.2e-17 63.3 5.5 6e-15 55.3 1.4 2.7 2 0 0 2 2 2 2 KR domain PP-binding PF00550.20 ETS88253.1 - 4.6e-12 46.0 0.0 1.4e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 ETS88253.1 - 5.5e-09 36.2 1.7 4e-06 26.9 1.1 3.4 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 ETS88253.1 - 2.7e-07 29.5 0.3 0.0085 14.8 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 ETS88253.1 - 5.2e-07 28.8 2.0 0.00095 18.1 0.0 2.8 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 ETS88253.1 - 3.1e-06 26.3 1.6 0.00095 18.1 0.2 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 ETS88253.1 - 5.3e-06 27.2 1.9 0.00014 22.7 0.1 3.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NmrA PF05368.8 ETS88253.1 - 0.0011 18.3 2.8 0.039 13.2 0.8 3.0 3 0 0 3 3 3 1 NmrA-like family THF_DHG_CYH_C PF02882.14 ETS88253.1 - 0.0036 16.4 0.2 0.01 14.8 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 ETS88253.1 - 0.012 15.2 1.5 0.033 13.7 0.4 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 ETS88253.1 - 0.023 14.4 2.8 0.023 14.4 0.8 1.8 2 0 0 2 2 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Wax2_C PF12076.3 ETS88253.1 - 0.26 10.9 0.0 0.51 10.0 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain Acetyltransf_1 PF00583.19 ETS88254.1 - 1.4e-16 60.2 0.1 2e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 ETS88254.1 - 2.7e-11 43.6 0.0 3.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 ETS88254.1 - 4.7e-11 42.8 0.0 6.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 ETS88254.1 - 5.4e-09 36.1 0.0 7.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ETS88254.1 - 1e-07 31.5 0.1 2.1e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 ETS88254.1 - 1.4e-07 31.5 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 ETS88254.1 - 5.2e-07 29.9 0.0 6.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ETS88254.1 - 2.8e-06 27.0 0.1 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 ETS88254.1 - 0.00023 21.0 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3323 PF11796.3 ETS88254.1 - 0.039 13.2 0.1 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Abhydrolase_6 PF12697.2 ETS88255.1 - 2.6e-11 43.8 0.0 3.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 ETS88255.1 - 6.3e-06 25.9 0.0 9.2e-05 22.1 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS88255.1 - 0.095 12.4 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4411 PF14367.1 ETS88256.1 - 0.22 11.2 3.1 0.53 9.9 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) FAR1 PF03101.10 ETS88257.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Ammonium_transp PF00909.16 ETS88258.1 - 2e-69 234.0 21.9 2.3e-69 233.7 15.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1212 PF06738.7 ETS88258.1 - 1 8.8 8.7 11 5.3 6.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Fungal_trans_2 PF11951.3 ETS88259.1 - 7.8e-14 51.0 0.3 3e-10 39.2 0.4 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 ETS88260.1 - 1.1e-37 129.6 24.1 1.5e-37 129.1 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 ETS88261.1 - 3.3e-57 193.4 0.0 4e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 ETS88261.1 - 7.1e-09 35.5 0.1 9.9e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 ETS88261.1 - 7.3e-09 35.1 0.0 5.8e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 ETS88261.1 - 6.9e-08 32.6 1.7 1e-07 32.0 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 ETS88261.1 - 2e-05 23.5 0.7 5.6e-05 22.0 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 ETS88261.1 - 4.9e-05 22.7 0.0 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 ETS88261.1 - 0.024 14.0 0.0 0.094 12.1 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 ETS88261.1 - 0.035 12.6 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AATase PF07247.7 ETS88262.1 - 1.2e-13 50.4 0.0 6.1e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase DUF3445 PF11927.3 ETS88263.1 - 1.1e-65 221.5 0.0 1.3e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF604 PF04646.7 ETS88266.1 - 1.4e-07 31.0 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 ETS88266.1 - 9.1e-05 21.7 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_90 PF05686.7 ETS88268.1 - 1.7e-16 59.9 0.4 7.5e-12 44.6 0.0 3.6 3 1 0 3 3 3 3 Glycosyl transferase family 90 Cpn60_TCP1 PF00118.19 ETS88269.1 - 6e-132 440.7 11.2 7.1e-132 440.4 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3071 PF11268.3 ETS88269.1 - 0.039 13.6 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) GARS_C PF02843.11 ETS88269.1 - 0.058 13.5 0.5 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain eIF2A PF08662.6 ETS88270.1 - 2.9e-36 125.0 6.6 6.6e-36 123.8 0.9 3.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 ETS88270.1 - 3.1e-06 27.0 0.0 8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ETS88270.1 - 8.5e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 ETS88270.1 - 3.8e-05 23.2 0.0 9.9e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 ETS88270.1 - 0.0011 18.7 0.0 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2458 PF10454.4 ETS88272.1 - 0.66 9.8 6.9 0.2 11.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) RabGAP-TBC PF00566.13 ETS88273.1 - 8e-33 113.7 0.0 1.3e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FA_desaturase PF00487.19 ETS88277.1 - 3e-25 89.1 11.8 4.8e-25 88.4 8.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 ETS88277.1 - 1.1e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Git3 PF11710.3 ETS88279.1 - 3.8e-16 59.2 6.9 1.4e-15 57.3 4.8 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 ETS88279.1 - 8.8e-08 31.5 6.6 1.4e-07 30.9 3.8 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 ETS88279.1 - 0.00065 18.6 4.0 0.0014 17.6 2.8 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 ETS88279.1 - 0.0093 15.7 0.4 0.028 14.1 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pkinase PF00069.20 ETS88280.1 - 3e-43 147.8 0.0 4.5e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 ETS88280.1 - 1.3e-36 125.2 0.0 2.5e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 ETS88280.1 - 7.4e-21 74.3 0.0 3.2e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 ETS88280.1 - 0.0013 18.2 0.2 0.25 10.9 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 ETS88280.1 - 0.0021 17.1 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.1 ETS88280.1 - 0.014 14.8 0.1 3.9 6.8 0.0 3.1 2 1 1 3 3 3 0 PQQ-like domain YrbL-PhoP_reg PF10707.4 ETS88280.1 - 0.029 13.7 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SWIB PF02201.13 ETS88281.1 - 1e-27 95.5 0.2 3.1e-27 94.0 0.1 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 ETS88281.1 - 1.4e-13 50.3 2.0 3.8e-13 48.9 0.6 2.1 2 0 0 2 2 2 1 DEK C terminal domain DUF3801 PF12687.2 ETS88281.1 - 0.003 17.1 1.9 0.0039 16.8 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3801)